title: [Pseudomembranous supraglottitis with airway compromise in a patient with recurrent tonsillar carcinoma].
abstract: OBJECTIVE
  In this report, we discuss a patient with acute pseudomembranous supraglottitis complicating recurrent tonsillar carcinoma and describe the ramifications of these disorders on perioperative management.
  
  
  METHODS
  The patient was an acutely ill man with a history of right tonsillar carcinoma originally treated with chemoradiation therapy and a radical neck dissection who presented with a brief history of fever, dyspnea, and stridor. The soft tissue of his neck was very stiff, his neck mobility was limited, and his mouth opening was restricted by pain and radiation-induced fibrosis. A nasal flexible fibreoptic laryngoscopy revealed a very large, indurated epiglottis almost completely obstructing the glottis. The aryepiglottic folds and false cords were edematous, and a gray pseudomembranous exudate was observed on the glottic surface, epiglottis, and true vocal cords. An elective tracheostomy was performed in the operating room using local anesthesia, and conscious sedation was avoided because of the potential for complete airway obstruction. General anesthesia was induced after the airway was secured, but trismus and tissue edema resulting from the acute infection made the glottis and surrounding structures nearly impossible to visualize during direct laryngoscopy. The patient was treated with intravenous antibiotics, and a subsequent direct laryngoscopy demonstrated tumour recurrence.
  
  
  CONCLUSIONS
  The case emphasizes that the perioperative management of imminent airway obstruction by acute supraglottitis complicating recurrent oropharyngeal cancer may optimally be approached by establishing a surgical airway under controlled operating conditions.
authors.affiliation: Clement J. Zablocki Veterans Affairs Medical Center, Anesthesia Service, 5000 W. National Avenue, Milwaukee, Wisconsin 53295, USA.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Klein
authors.forename: David G
authors.initials: DG
authors.lastname: Parkins
authors.forename: Sweeta D
authors.initials: SD
authors.lastname: Gandhi
authors.forename: Zafar
authors.initials: Z
authors.lastname: Iqbal
authors.forename: William T
authors.initials: WT
authors.lastname: Schmeling
authors.forename: Paul S
authors.initials: PS
authors.lastname: Pagel
mesh_terms: D000208:Acute Disease; D000402:Airway Obstruction / Q000209:etiology* / Q000601:surgery; D000768:Anesthesia, General; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002100:Cachexia / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D004417:Dyspnea / Q000209:etiology; D004825:Epiglottis / Q000000981:diagnostic imaging; D004826:Epiglottitis / Q000150:complications* / Q000188:drug therapy; D005334:Fever / Q000209:etiology; D005931:Glottis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications* / Q000175:diagnosis; D014066:Palatine Tonsil / Q000000981:diagnostic imaging; D012135:Respiratory Sounds / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014067:Tonsillar Neoplasms / Q000150:complications*; D014139:Tracheostomy
chemical_list: D000900:Anti-Bacterial Agents