[Chaemotaxic activity of neutrophils and monocytes in patients with vulgar psoriasis].
In consideration of confirmed disturbances of some functional activities of neutrophils and monocytes in patients with psoriasis vulgaris, this work had a purpose to investigate chaemotactic activity of neutrophils and monocytes in patients with psoriasis vulgaris. Totaly were examined 100 patients with psoriasis vulgaris, which were devidede in three hroups: acute exanthematic (A) forme of disease (20 patients), chronic stable (H) form of disease (16 patients) and acute phase of chronic (AH) form of disease (64 patients). Controle group were composed of 50 healthy persons, chaemotactic activity of neutrophils and monocytes were examined by the "skin windows test", method by Eitzman. Results indicate that cellular migration is significant higher in all groups of patients, significantly disturbances of procentual amount of neutrophils and monosytes in compose of cellular infiltrate, were not confirm in neither group of examinees. Significant differens were not confirm in comparasion of the obtaind results. On the base of results, we can conclude that chaemotactic activity of neutrophils and monocytes in higher in patients of psoriasis vulgaris independent from the exudation, infiltration, duration and course of disease.
Poljacki
M
M
Jovanović
M
M
Budakov
M
M
Djuran
V
V
Subotić
M
M
D002634:Chemotaxis, Leukocyte; D006801:Humans; D009000:Monocytes / Q000502:physiology*; D009504:Neutrophils / Q000502:physiology*; D011565:Psoriasis / Q000473:pathology / Q000503:physiopathology*