[The superficial architectonics of peripheral blood lymphocytes in patients with pulmonary tuberculosis].
Peripheral blood lymphocytes were electron microscopically studied in patients with disseminated drug-sensitive and drug-resistant pulmonary tuberculosis before and during specific antituberculous chemotherapy. There was a tendency for an increase in the count of lymphocytes with membranous morphostructural changes during the therapy, which was more clearly defined in the drug-resistant type of the infectious process. It is suggested that antituberculous drugs have a damaging effect on the membrane of immunocompetent blood cells.
Novitskiĭ
V V
VV
Strelis
A K
AK
Urazov
O I
OI
Voronkova
O V
OV
Mikhalenko
A N
AN
Shevtsova
N M
NM
Sinitsyna
V A
VA
Khasanova
R R
RR
Pirogova
N P
NP
Rybakov
M A
MA
D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000276:immunology*
D000995:Antitubercular Agents