title: [Preparation for colonoscopy using 1,000 ml Magcorol P isotonic solution in the absence of dietary restrictions or use of purgatives on the preceding day].
abstract: Colonic lavage using about 2,000 mL of solution is performed routinely in Japan. However, consumption of such large amounts of fluid may be difficult for elderly individuals. From personal experience, it was observed that in European countries, the Modified Brown Method is mainly used, where patients are instructed to take 3,000 to 5,000 mL of water and a purgative on the day preceding colonoscopy. In the present study, dietary restrictions and use of purgatives on the preceding day were omitted, to reduce the burden on patients. The volume of lavage solution was limited to 1,000 mL, which was taken on the day of colonoscopy. This study included four groups, receiving various drugs, based on examination of 882 responses from 786 patients, to a questionnaire. Group1: 1 pack Niflec (Polyethylene glycol)+ 50g Magcorol(Citrate magnesium); group 2: 50g Magcorol + 10mL laxoberon (sodium picosulfate); Group 3; 60g Magcorol + 10mL laxoberon and Group 4 55g Magcorol + 20mL laxoberon . The results of Evaluation of Colonoscopic Cleansing showed, the satisfactory level of subjects on the 1000 mL method was similar to those on the 2,000 mL method. In addition, 796 (96%) of 882 subjects answered that the 1,000-mL lavage method was tolerable. The final group received a lavage solution prepared by dissolving 55 g of Magcorol P and 20 mL of Laxoberon in 1,000 mL of water. On the day of colonoscopy at 8:30 in the morning, patients took 3 Gasmotin tablets and lavage solution ingestion was induced at 09:00 and completed within 15 minutes. Cleansing efficacy in this group was 95%. A Glycerine enema was used when necessary, since its cleansing effect in patients (13%) was comparable to patients without enema. Moreover, in the questionnaire patients indicated that enemas were more acceptable than additional consumption of lavage solution. The following advantages were observed with the 1,000 mL lavage method: a) sufficient sleep on the preceding day due to the absence of dietary restrictions or use of purgatives; b) lesser concern regarding urge to evacuate on the way to the hospital and c) feeling of security in taking the lavage solution at the hospital.
authors.affiliation: Department of Diagnostic & Therapeutic Endoscopy, Yamagata Tokushuhkai General Hospital.
authors.forename: Matatoshi
authors.initials: M
authors.lastname: Dohmoto
mesh_terms: D002400:Cathartics / Q000008:administration & dosage*; D002951:Citrates; D019343:Citric Acid / Q000008:administration & dosage*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007552:Isotonic Solutions; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage*; D010847:Picolines / Q000008:administration & dosage*; D007507:Therapeutic Irrigation; D013997:Time Factors
chemical_list: D002400:Cathartics; D002951:Citrates; D007552:Isotonic Solutions; D009942:Organometallic Compounds; D010847:Picolines; D019343:Citric Acid; C005701:picosulfate sodium; C110422:magnesium citrate