title: Cerebral venous thrombosis after immune thrombocytopenic purpura and anti-D immune globulin therapy.
abstract: Cerebral venous thrombosis has multiple etiologies and a wide variety of clinical manifestations. This article reports on a young girl who developed cerebral venous thrombosis after intravenous anti-D immune globulin therapy for immune thrombocytopenic purpura. In this case, venous infarction was manifested by an unusual pattern of restricted diffusion limited to the corpus callosum. The cause of cerebral venous thrombosis in this patient may be related to both immune thrombocytopenia and immunoglobulin therapy.
authors.affiliation: Department of Pediatrics, Section of Neurology, Children's Mercy Hospital and Clinics, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA.
authors.forename: Husam R
authors.initials: HR
authors.lastname: Kayyali
authors.forename: Ahmed T
authors.initials: AT
authors.lastname: Abdelmoity
authors.forename: M Craig
authors.initials: MC
authors.lastname: Morriss
authors.forename: William D
authors.initials: WD
authors.lastname: Graf
mesh_terms: D000208:Acute Disease; D020520:Brain Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D002648:Child; D003337:Corpus Callosum / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D010690:Phlebography; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications* / Q000188:drug therapy* / Q000276:immunology; D018029:Rho(D) Immune Globulin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D018029:Rho(D) Immune Globulin