Dedifferentiated liposarcoma presenting as jejunal polyp. Case report.
We report a case of primary jejunal dedifferentiated liposarcoma presenting as a submucosal polyp mimicking a benign neoplasm. This is an extremely rare presentation. The histological feature of interest was the spindle cell lipoma-like appearance of the well-differentiated component. The use of MDM2 immunostaining in differentiating benign lipomatous tumours from well-differentiated liposarcomas is mentioned, which is of value especially in lipomatous tumours of the gut where ulcerated benign tumours can show varying degrees of atypia.
Manipadam
Marie Therese
MT
Department of General Pathology, Christian Medical College, Vellore, India. mtm2005@cmcvellore.ac.in
Singh
Reecha
R
Vijay
Abraham
A
D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D007417:Intestinal Polyps / Q000473:pathology*; D007580:Jejunal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008080:Liposarcoma / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D051736:Proto-Oncogene Proteins c-mdm2 / Q000378:metabolism
C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2