title: Rapid improvement of radiation-induced neovascular glaucoma and exudative retinal detachment after a single intravitreal ranibizumab injection.
abstract: Neovascular glaucoma is a serious complication arising from irradiation of uveal melanoma. Treatment options include panretinal photocoagulation, peripheral retina cryotherapy, photodynamic therapy with verteporfin, triamcinolone injections and surgical removal of the dying tumour mass. Nevertheless, enucleation of the affected eye often is inevitable. The authors describe a case report of a radiation-induced neovascular glaucoma and exudative retinal detachment caused by malignant melanoma of the uvea that was treated with intravitreal ranibizumab.
authors.forename: Roman
authors.initials: R
authors.lastname: Dunavoelgyi
authors.forename: Martin
authors.initials: M
authors.lastname: Zehetmayer
authors.forename: Christian
authors.initials: C
authors.lastname: Simader
authors.forename: Ursula
authors.initials: U
authors.lastname: Schmidt-Erfurth
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage* / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D004334:Drug Administration Schedule; D005122:Exudates and Transudates / Q000378:metabolism*; D015355:Glaucoma, Neovascular / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007267:Injections; D011832:Radiation Injuries / Q000150:complications*; D000069579:Ranibizumab; D012163:Retinal Detachment / Q000188:drug therapy* / Q000209:etiology* / Q000378:metabolism; D014822:Vitreous Body
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000069579:Ranibizumab