Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation.
BACKGROUND
There is little information about the efficacy of ticlopidine plus aspirin after sirolimus-eluting stent (SES) implantation.


RESULTS
The incidence of stent thrombosis was evaluated in 1,029 patients receiving ticlopidine and aspirin after SES deployment. Clinical follow-up was obtained in 98.9% (mean follow-up 17.0+/-7.9 months). Early stent thrombosis was observed in 5 patients (0.49%). There was 1 case each of late (0.1%) and very late stent thrombosis (0.1%).


CONCLUSIONS
Late and very late stent thrombosis in Japanese patients receiving ticlopidine and aspirin after SES deployment occurs infrequently.
Kitahara
Hideki
H
Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Kobayashi
Yoshio
Y
Fujimoto
Yoshihide
Y
Nakamura
Yoshitake
Y
Nakayama
Takashi
T
Kuroda
Nakabumi
N
Himi
Toshiharu
T
Miyazaki
Akira
A
Komuro
Issei
I
D000368:Aged; D001241:Aspirin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D020123:Sirolimus / Q000008:administration & dosage; D013927:Thrombosis / Q000209:etiology*; D013988:Ticlopidine / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome
D013988:Ticlopidine; D001241:Aspirin; D020123:Sirolimus