Rhipicephalus (Boophilus) microplus: distinct acute phase proteins vary during infestations according to the genetic composition of the bovine hosts, Bos taurus and Bos indicus.
Tick bites may trigger acute phase responses. Positive and negative acute phase proteins were measured in infested cattle genetically resistant and susceptible to ticks. During heavier infestations levels of haptoglobin increased significantly in susceptible bovines; levels of serum amyloid A increased in resistant bovines; levels of alpha-1-acid glycoprotein decreased significantly in resistant bovines; levels of transferrin decreased significantly in susceptible bovines. In conclusion, tick infestations trigger acute phase responses and enhancement of specific acute phase proteins differs according to the genetic composition of hosts. Acute phase proteins may constitute useful biological signatures for monitoring the stress induced by tick infestations.
Carvalho
Wanessa Araújo
WA
Department of Veterinary Pathology, School of Agricultural and Veterinary Sciences, São Paulo State University, Jaboticabal, São Paulo, Brazil.
Bechara
Gervasio Henrique
GH
Moré
Daniela Dantas
DD
Ferreira
Beatriz Rossetti
BR
da Silva
João Santana
JS
de Miranda Santos
Isabel K Ferreira
IK
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000210:Acute-Phase Reaction / Q000235:genetics / Q000276:immunology; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000235:genetics / Q000276:immunology* / Q000469:parasitology; D005260:Female; D006242:Haptoglobins / Q000378:metabolism; D006790:Host-Parasite Interactions / Q000235:genetics* / Q000276:immunology; D007113:Immunity, Innate / Q000235:genetics / Q000276:immunology; D008297:Male; D009961:Orosomucoid / Q000378:metabolism; D048494:Rhipicephalus / Q000276:immunology / Q000502:physiology*; D000685:Serum Amyloid A Protein / Q000378:metabolism; D013984:Tick Infestations / Q000235:genetics / Q000276:immunology / Q000662:veterinary*; D014168:Transferrin / Q000378:metabolism
D000209:Acute-Phase Proteins; D006242:Haptoglobins; D009961:Orosomucoid; D000685:Serum Amyloid A Protein; D014168:Transferrin