Foveal crowding in posterior cortical atrophy: a specific early-visual-processing deficit affecting word reading.
Visual crowding is a form of masking in which single-letter identification is compromised by the presence of additional letters or other simple visual forms in close proximity. This behavioural phenomenon has been studied most frequently in the context of amblyopic and normal peripheral vision. In the current study, we investigate this phenomenon in the context of two patients with peripheral dyslexia and a third with visual disorientation consequent to bilateral posterior cortical atrophy. In one case, reading showed the effects of word length typical of letter-by-letter reading, whereas the second case was unable to read any whole words. In a series of letter identification tasks, recognition accuracy was shown to decrease significantly in the presence of a range of flanking stimuli (e.g., letters, digits, letter fragments). Compatible with previous reports of the crowding phenomenon, the flanking effect was strengthened by increasing flanker proximity but was unaffected by target or flank size, flank contrast, target-flank lexicality, or flank category. One patient also showed amelioration of the flanking effect when the target and flankers were of opposite contrast polarity. To the best of our knowledge, this is the first demonstration of visual crowding in individuals with posterior cortical atrophy. We consider the relevance of these empirical findings to accounts of the letter-by-letter reading form of peripheral dyslexia. In particular, we suggest that crowding constitutes one specific form of early-visual-processing deficit, which impairs the reading process.
Crutch
Sebastian J
SJ
Dementia Research Centre, Department of Neurodegeneration, Institute of Neurology, University College London, London, UK. s.crutch@dementia.ion.ucl.ac.uk
Warrington
Elizabeth K
EK
D000368:Aged; D000513:Alpha Rhythm; D000544:Alzheimer Disease / Q000175:diagnosis / Q000503:physiopathology*; D001284:Atrophy; D001288:Attention / Q000502:physiology; D002540:Cerebral Cortex / Q000473:pathology*; D004192:Discrimination, Psychological / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology; D004411:Dyslexia, Acquired / Q000175:diagnosis / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D005584:Fovea Centralis / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology; D010296:Parietal Lobe / Q000473:pathology; D010364:Pattern Recognition, Visual / Q000502:physiology; D010470:Perceptual Masking / Q000502:physiology*; D013826:Theta Rhythm; D014794:Visual Fields / Q000502:physiology