title: Update for nurse anesthetists--part 5--Transfusion-related acute lung injury.
abstract: Acute onset of dyspnea, fever, hypotension, and cough during or soon after a blood or blood-product transfusion has been described in the literature since the early 1950s. Between 2003 and 2005, transfusion-related acute lung injury (TRALI) surpassed ABO incompatibility as the number one cause of transfusion-related mortality in the United States, as reported to the Food and Drug Administration. Prompt recognition and appropriate intervention are required to reduce mortality. Prevention of TRALI represents a complex challenge. There is no single intervention that will prevent every case of TRALI, but several interventions have been proposed to reduce the risk.
authors.affiliation: Wesley Long Community Hospital Division, Moses Cone Health System, Greensboro, North Carolina, USA. crnadad@yahoo.com
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Joyce
mesh_terms: D000328:Adult; D000368:Aged; D004509:Education, Nursing, Continuing; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009719:Nurse Anesthetists; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012128:Respiratory Distress Syndrome / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D065227:Transfusion Reaction