[Diagnosis of hepatic failure at the patients with abdominal sepsis].
Results of prospective study of 398 patients with abdominal sepsis are analyzed. It is demonstrated that acute hepatic failure occurs at 45% of these patients and it is direct cause of death at 28% of them. Blood level of triglycerides and alkaline phosphatase are reliable markers of hepatic dysfunction at abdominal sepsis. Concentrations of these markers are associated with severity of patients and systemic inflammation syndrome, and also with the number of performed laparotomies.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017114:Liver Failure, Acute / Q000175:diagnosis* / Q000209:etiology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000150:complications*; D011446:Prospective Studies; D012372:ROC Curve; D018805:Sepsis / Q000150:complications*