title: A non-endocrine cause of testicular enlargement mimicking precocious puberty: testicular microlithiasis.
abstract: Untimely bilateral testicular enlargement greater than 3 ml is suggestive of precocious puberty, in which an underlying organic disease is more common in boys than in girls. We describe a 7 1/2 year-old boy presenting with testicular enlargement due to testicular microlithiasis. Following hormonal tests, diagnosis was based on ultrasonographic findings. Three years follow-up of the patient revealed normal pubertal progress and no malignant evolution. Testicular microlithiasis is a rare cause of testicular enlargement and pediatricians should take this disease into account in the differential diagnosis of suspected precocious puberty.
authors.affiliation: Department of Pediatric Endocrinology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey. ece.bober@deu.edu.tr
authors.forename: Ece
authors.initials: E
authors.lastname: Bober
authors.forename: Bumin
authors.initials: B
authors.lastname: Dundar
authors.forename: Korcan
authors.initials: K
authors.lastname: Demir
authors.forename: Ayhan
authors.initials: A
authors.lastname: Abaci
authors.forename: Handan
authors.initials: H
authors.lastname: Cakmakçi
authors.forename: Atilla
authors.initials: A
authors.lastname: Buyukgebiz
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000097:blood; D006801:Humans; D006984:Hypertrophy; D020347:Lithiasis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011629:Puberty, Precocious / Q000175:diagnosis*; D013733:Testicular Diseases / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013737:Testis / Q000000981:diagnostic imaging / Q000473:pathology*; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone