Case report: Borrelia valaisiana infection in a Japanese man associated with traveling to foreign countries.
A 78-year-old Japanese man who had clinical symptoms and a flu-like illness with fever, chills, diarrhea, and arthralgia had traveled to Cambodia and Khabarovsk, Russia, before the onset of symptoms and illness. He had been bitten by an Ixodes persulcatus tick in which the DNA of Borrelia valaisiana was detected. The patient's symptoms improved rapidly after treatment with minocycline. Serologic examination detected antibodies to Lyme disease Borrelia. An flaB polymerase chain reaction with the patient's plasma amplified a DNA fragment similar to that of B. valaisiana.
Saito
Kan
K
Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.
Ito
Takafumi
T
Asashima
Nobuko
N
Ohno
Minoru
M
Nagai
Ryozo
R
Fujita
Hiromi
H
Koizumi
Nobuo
N
Takano
Ai
A
Watanabe
Haruo
H
Kawabata
Hiroki
H
D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001898:Borrelia / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D001899:Borrelia Infections / Q000175:diagnosis / Q000382:microbiology*; D005408:Flagellin / Q000235:genetics; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood / Q000378:metabolism; D018884:Ixodes / Q000145:classification / Q000235:genetics; D007564:Japan; D008297:Male; D008911:Minocycline / Q000008:administration & dosage; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D014195:Travel; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D007075:Immunoglobulin M; D012336:RNA, Ribosomal, 16S; D005408:Flagellin; C416532:flaB flagellin; D008911:Minocycline