[A puzzling case of portal hypertension in a patient with human immunodeficiency and hepatitis C virus co-infection].
The case of a human immunodeficiency virus (HIV) and hepatitis C virus (HCV)-coinfected patient with a medical history of deep venous thrombosis is presented. A liver biopsy, performed for unexpected portal hypertension, showed vascular lesions presenting as nodular regenerative hyperplasia. Vascular liver diseases seem to be a new cause of chronic liver disease in HIV-infected patients receiving combined antiretroviral therapy. The syndrome of HIV-associated liver vasculopathy is discussed.
Mallet
Vincent
V
INSERM U567, Unité d'hépatologie, Pôle d'hépato-gastroentérologie médicochirurgical, Hôpital Cochin, 27 rue du Faubourg Saint-Jacques, Paris. vincent.mallet@cch.aphp.fr
Pol
Stanislas
S
D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D001706:Biopsy; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D006975:Hypertension, Portal / Q000150:complications*; D008099:Liver / Q000473:pathology; D008115:Liver Regeneration; D008297:Male
D044966:Anti-Retroviral Agents