title: My headache does not get better when I lie down: spontaneous intracranial hypotension complicated by venous thrombosis.
abstract: Two patients with spontaneous intracranial hypotension (SIH) subsequently developed cerebral venous thrombosis (CVT) when their headache lost its distinctive orthostatic characteristic. In addition to typical MRI features of tonsillar descent, subdural fluid collections, and diffuse pachymeningeal enhancement, hyperintense thrombi were detected in the dural sinuses, and filling defects on magnetic resonance venography. Knowledge of the typical neuroimaging features of SIH and CVT and change in headache characteristics are important for prompt diagnosis and treatment.
authors.affiliation: Department of Neurology, National Neuroscience Institute, Singapore.
authors.forename: Kevin
authors.initials: K
authors.lastname: Tan
authors.forename: Narayanaswamy
authors.initials: N
authors.lastname: Venketasubramanian
authors.forename: Cheng Yang
authors.initials: CY
authors.lastname: Hwang
authors.forename: C C Tchoyoson
authors.initials: CC
authors.lastname: Lim
mesh_terms: D000328:Adult; D005260:Female; D006261:Headache / Q000209:etiology* / Q000473:pathology; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods; D020246:Venous Thrombosis / Q000150:complications* / Q000473:pathology