title: Dedifferentiated liposarcoma presenting as jejunal polyp. Case report.
abstract: We report a case of primary jejunal dedifferentiated liposarcoma presenting as a submucosal polyp mimicking a benign neoplasm. This is an extremely rare presentation. The histological feature of interest was the spindle cell lipoma-like appearance of the well-differentiated component. The use of MDM2 immunostaining in differentiating benign lipomatous tumours from well-differentiated liposarcomas is mentioned, which is of value especially in lipomatous tumours of the gut where ulcerated benign tumours can show varying degrees of atypia.
authors.affiliation: Department of General Pathology, Christian Medical College, Vellore, India. mtm2005@cmcvellore.ac.in
authors.forename: Marie Therese
authors.initials: MT
authors.lastname: Manipadam
authors.forename: Reecha
authors.initials: R
authors.lastname: Singh
authors.forename: Abraham
authors.initials: A
authors.lastname: Vijay
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D007417:Intestinal Polyps / Q000473:pathology*; D007580:Jejunal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008080:Liposarcoma / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D051736:Proto-Oncogene Proteins c-mdm2 / Q000378:metabolism
chemical_list: C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2