title: A review of anti-septic agents for pre-operative skin preparation.
abstract: Pre-operative skin preparation of the surgical site using appropriate anti-septic product is recognized by the Centers for Disease Control and Prevention Guideline for Prevention of Surgical Site Infection, 1999, as a strongly recommended intervention to prevent surgical site infection. This article reviews anti-septic surgical skin preparation products according to the Food and Drug Administration classifications, efficacy, and safety. It also examines pertinent research regarding anti-septic products. This information provides the peri-operative registered nurse with information to make appropriate decisions when choosing anti-septic skin preparation products for surgical patients.
authors.affiliation: marydigison@texashealth.org
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Digison
mesh_terms: D019840:2-Propanol / Q000627:therapeutic use; D000279:Administration, Cutaneous; D000891:Anti-Infective Agents, Local / Q000009:adverse effects / Q000145:classification / Q000627:therapeutic use*; D001207:Asepsis / Q000379:methods / Q000592:standards; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D004338:Drug Combinations; D006801:Humans; D017053:Infection Control / Q000379:methods / Q000592:standards; D007466:Iodophors / Q000627:therapeutic use; D018579:Patient Selection; D013527:Perioperative Nursing; D011206:Povidone-Iodine / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D011300:Preoperative Care / Q000379:methods* / Q000451:nursing / Q000592:standards; D012449:Safety; D017592:Skin Care / Q000379:methods* / Q000451:nursing / Q000592:standards; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D014486:United States Food and Drug Administration; D014992:Xylenes / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D007466:Iodophors; D014992:Xylenes; C007027:chloroxylenol; D011206:Povidone-Iodine; C010882:chlorhexidine gluconate; D019840:2-Propanol; D002710:Chlorhexidine