title: [A case of sclerosing cholangitis showing response to prednisolone].
abstract: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive fibrosis and destruction of intra- and extrahepatic bile ducts resulting in hepatic failure and death. Only the liver transplantation is the possible treatment for patients to survive. There has been a few reports that steroid is an effective treatment in autoimmune variant sclerosing cholangitis, which is thought to be a familial diseases with different etiology, and steroid responsive biliary strictures be named as immunoglobulin G4 (IgG4)-associated cholangitis (IAC). There is no reliable data regarding effective steroid treatment in autoimmune variant sclerosing cholangitis in Korea. We report a case of 32-year-old male with sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and liver biopsy, showing favorable response to prednisolone therapy.
authors.affiliation: Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea.
authors.forename: Yo Sig
authors.initials: YS
authors.lastname: Shin
authors.forename: Yong Seok
authors.initials: YS
authors.lastname: Jang
authors.forename: Min Kyoung
authors.initials: MK
authors.lastname: Kang
authors.forename: Byoung Kuk
authors.initials: BK
authors.lastname: Jang
authors.forename: Kyung Sik
authors.initials: KS
authors.lastname: Park
authors.forename: Jae Seok
authors.initials: JS
authors.lastname: Hwang
authors.forename: Jung Hyeok
authors.initials: JH
authors.lastname: Kwon
authors.forename: Yu Na
authors.initials: YN
authors.lastname: Kang
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone