title: Papillary tumor of the pineal region.
abstract: A 48-year-old female presented with an extremely rare primary tumor of the pineal region with papillary features manifesting as morning headaches persisting for 1 month. Magnetic resonance imaging showed a well-defined mass, with some cystic components, in the region of the pineal gland. The tumor was completely removed through an occipital transtentorial approach in the prone position. Histological examination found a distinctive papillary growth pattern in which the vessels were covered by multiple layers of tumor cells. The histological diagnosis was papillary tumor of the pineal region (PTPR), which has recently been described as a distinct clinicopathological entity requiring careful follow up because the prognosis is not well understood. Postoperatively, the patient has continued to do well, with no recurrence at the 8-month follow-up examination. PTPR should be considered in the differential diagnosis of pineal tumors. PTPR may have been frequently misinterpreted in the past as either ependymoma or choroid plexus papilloma due to the similar morphology.
authors.affiliation: Department of Neurosurgery, Nagasaki Prefectural Shimabara Hospital, Shimabara, Nagasaki, Japan. i-kwhr@umin.ac.jp
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kawahara
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Tokunaga
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yagi
authors.forename: Masachika
authors.initials: M
authors.lastname: Iseki
authors.forename: Kuniko
authors.initials: K
authors.lastname: Abe
authors.forename: Tomayoshi
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010870:Pineal Gland; D010871:Pinealoma / Q000175:diagnosis* / Q000628:therapy*