title: Histological analysis of microbleed after surgical resection in a patient with moyamoya disease.
abstract: A 65-year-old male with moyamoya disease underwent surgical resection of a microbleed simultaneously with revascularization surgery. Histological examination identified several fragile arteries surrounding the microbleed. Microbleeds detected by T2*-weighted magnetic resonance imaging are considered to be a general marker of vascular vulnerability in cerebral angiopathy with a tendency to bleeding. The microbleeds observed in patients with moyamoya disease probably originate in bleeding from the fragile arteries.
authors.affiliation: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, Japan. kikuta@kuhp.kyoto-u.ac.jp
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Kikuta
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takagi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nozaki
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Okada
authors.forename: Nobuo
authors.initials: N
authors.lastname: Hashimoto
mesh_terms: D000368:Aged; D006801:Humans; D020300:Intracranial Hemorrhages / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008833:Microcirculation; D009072:Moyamoya Disease / Q000150:complications* / Q000601:surgery