[Implementation of cytology images classification--the Bethesda 2001 System--in a group of screened women from Podlaskie region--effect evaluation].
Increasing knowledge concerning carcinogenesis within cervical epithelium has forced us to make continues modifications of cytology classification of the cervical smears. Eventually, new descriptions of the submicroscopic cytomorphological abnormalities have enabled the implementation of Bethesda System which was meant to take place of the former Papanicolaou classification although temporarily both are sometimes used simultaneously.


OBJECTIVE
The aim of this study was to compare results of these two classification systems in the aspect of diagnostic accuracy verified by further tests of the diagnostic algorithm for the cervical lesion evaluation.


METHODS
The study was conducted in the group of women selected from general population, the criteria being the place of living and cervical cancer age risk group, in the consecutive periods of mass screening in Podlaski region. The performed diagnostic tests have been based on the commonly used algorithm, as well as identical laboratory and methodological conditions.


RESULTS
Performed assessment revealed comparable diagnostic accuracy of both analyzing classifications, verified by histological examination, although with marked higher specificity for dysplastic lesions with decreased number of HSIL results and increased diagnosis of LSILs. Higher number of performed colposcopies and biopsies were an additional consequence of TBS classification. Results based on Bethesda System made it possible to find the sources and reasons of abnormalities with much greater precision, which enabled causing agent treatment.


CONCLUSIONS
Two evaluated cytology classification systems, although not much different, depicted higher potential of TBS and better, more effective communication between cytology laboratory and gynecologist, making reasonable implementation of The Bethesda System in the daily cytology screening work.
Zbroch
Tomasz
T
Klinika Rozrodczości i Endokrynologii Ginekologicznej Samodzielnego Publicznego Szpitala Klinicznego Akademii Medycznej w Białymstoku. tzbroch@amb.edu.pl
Knapp
Paweł Grzegorz
PG
Knapp
Piotr Andrzej
PA
D000328:Adult; D000465:Algorithms; D022003:Cell Nucleus Structures / Q000000981:diagnostic imaging / Q000473:pathology; D003581:Cytodiagnosis / Q000592:standards*; D005260:Female; D006801:Humans; D019044:Image Cytometry / Q000592:standards; D008875:Middle Aged; D065006:Papanicolaou Test; D011044:Poland; D014463:Ultrasonography; D002578:Uterine Cervical Dysplasia / Q000145:classification* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000145:classification* / Q000473:pathology; D014626:Vaginal Smears