Detection of ethyl glucuronide in dried human blood using LC-MS/MS.
Ethyl glucuronide, as a direct metabolite of ethanol degradation, has proven useful as a long-term marker in many forensic applications. The inability to determine ethyl glucuronide in dried blood left a missing link in many investigations. Here, we describe a new method based on mass spectrometry in a Pauli-type ion trap in order to determine this substance in dried blood samples.
Kaufmann
Eckhard
E
Department of General Physiology, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany. eckhard.kaufmann@uni-ulm.de
Alt
Andreas
A
D000428:Alcohol Drinking; D015415:Biomarkers / Q000032:analysis; D001774:Blood Chemical Analysis; D002853:Chromatography, Liquid / Q000379:methods*; D005260:Female; D053593:Forensic Toxicology; D005965:Glucuronates / Q000032:analysis*; D006801:Humans; D008297:Male; D053719:Tandem Mass Spectrometry / Q000379:methods*
D015415:Biomarkers; D005965:Glucuronates; C093924:ethyl glucuronide