Anterior segment biometry with 2 imaging technologies: very-high-frequency ultrasound scanning versus optical coherence tomography.
OBJECTIVE
To determine the interchangeability of 2 anterior segment imaging systems: a very-high-frequency (VHF) ultrasound scanning system (Artemis 2, Ultralink LLC) and an optical coherence tomography (OCT) system (Visante, Zeiss).


METHODS
Vissum Instituto Oftalmologico de Alicante, Alicante, Spain.


METHODS
This study comprised 20 eyes without pathology or previous surgery. The anterior chamber depth (ACD), central corneal thickness (CCT), angle-to-angle distance (ATA), and the iridocorneal angle size (IAS) at the 0-degree and 180-degree positions were measured with 2 imaging techniques: VHF ultrasound scanning and OCT. Analysis of agreement and interchangeability was performed by the Bland and Altman method. In addition, each measurement was performed 3 times consecutively to determine intrasession repeatability by means of the coefficient of variation (CV) and the intraclass correlation coefficient (ICC).


RESULTS
No statistically significant differences were found between imaging techniques in ACD, CCT, or ATA (P>.40). The ranges of agreement were 0.20 mm, 16.11 mum, and 0.80 mm for ACD, CCT, and ATA, respectively. Regarding IAS, no statistically significant differences were found in the nasal (P = .78) or temporal (P = .63) measurements between devices. However, the range of agreement for nasal (14.3 degrees) and temporal (14.90 degrees) values was relevant, indicating the 2 techniques cannot be used interchangeably for IAS measurement. Excellent intrasession repeatability scores were obtained (CV and ICC).


CONCLUSIONS
The Artemis 2 and the Visante OCT systems provide equivalent and repeatable measurements of the ACD, CCT, and ATA and can be used interchangeably for these purposes.
Piñero
David P
DP
Vissum/Instituto Oftalmológico de Alicante, Universidad Miguel Hernández, Alicante, Spain.
Plaza
Ana Belén
AB
Alió
Jorge L
JL
D000328:Adult; D000869:Anterior Eye Segment / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D001699:Biometry; D006801:Humans; D033401:Microscopy, Acoustic / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*