title: Littoral-cell angioma of the spleen: a case report.
abstract: Littoral-cell angioma (LCA) is a primary splenic vascular tumor that arises from the normal littoral cells lining the sinus channels of the splenic red pulp. We report a case of LCA of the spleen, which has been infrequently communicated in the literature. A 76-year-old man with a 2-wk history of weight loss, abdominal pain and changes in bowel habits was admitted to our hospital. Imaging studies (CT and MRI) showed multiple lesions in the spleen. Splenectomy was performed. Lining cells were positive for CD31/CD68 markers. Our case was associated with a serrated colonic adenoma. LCA is a benign vascular tumor of the spleen that needs to be included in the differential diagnosis of multiple splenic nodules.
authors.affiliation: Department of Gastroenterology, Hospital Donostia, Paseo Beguiristain, s/n, 20014, San Sebastian (Gipuzkoa), Spain. acosme@chdo.osakidetza.net
authors.forename: Angel
authors.initials: A
authors.lastname: Cosme
authors.forename: Angel
authors.initials: A
authors.lastname: Tejada
authors.forename: Luis
authors.initials: L
authors.lastname: Bujanda
authors.forename: Manuel
authors.initials: M
authors.lastname: Vaquero
authors.forename: José Luis
authors.initials: JL
authors.lastname: Elorza
authors.forename: Evelia
authors.initials: E
authors.lastname: Ojeda
authors.forename: Unai
authors.initials: U
authors.lastname: Goikoetxea
mesh_terms: D000368:Aged; D015703:Antigens, CD / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D006391:Hemangioma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism; D013154:Spleen / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D015415:Biomarkers; D019408:Platelet Endothelial Cell Adhesion Molecule-1; C067980:CD68 antigen, human; D000097382:CD68 Molecule