[Clinical observation on treatment of oligospermia and asthenospermia with Liuwu Shengjing Decoction].
OBJECTIVE
To investigate the clinical efficacy and safety of Liuwu Shengjing Decoction (LWD) in treating oligospermia and asthenospermia.


METHODS
One hundred and fourteen patients were randomized into two groups, the treated group administrated with self-formulated LWD, and the control group administrated with Wuzi Yanzong Pill (WYP). All were treated for 3 months. Patients' semen was analyzed before and after treatment, and the therapeutic efficacy was evaluated.


RESULTS
The total effective rate was 94.8% in the treated group, with a partner pregnant rate of 8.6% (5/58), while in the control group, they were 85.7% and 5.4% (3/56) respectively. The efficacy in the treated group was better (P = 0.03). Patients' sperm count and viability of sperm were improved in both groups (P < 0.05 or P < 0.01), but the improvement in the treated group was superior (P < 0.05).


CONCLUSIONS
LWD could effectively improve the condition of male infertility with oligospermia and asthenospermia.
Guo
Jun
J
Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing. guojun1126@sina.com
Song
Chun-sheng
CS
Geng
Qiang
Q
D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D009845:Oligospermia / Q000150:complications / Q000188:drug therapy*; D008517:Phytotherapy; D013081:Sperm Motility / Q000187:drug effects*; D016896:Treatment Outcome; D055815:Young Adult
D004365:Drugs, Chinese Herbal; C533488:liuwu shengjing