title: Persistence of vaccinia at the site of smallpox vaccination.
abstract: Persistence of vaccinia at vaccination sites may help determine the risk associated with secondary transmission. Culture, PCR, and antigen detection were performed on serial vaccination site swab specimens. On day 21 after vaccination, 37% of volunteers were culture positive, most of whom had received vaccine for the first time. Vaccinia is detectable at least through day 21 after vaccination.
authors.affiliation: Infectious Diseases Service, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
authors.forename: James F
authors.initials: JF
authors.lastname: Cummings
authors.forename: Mark E
authors.initials: ME
authors.lastname: Polhemus
authors.forename: Clifton
authors.initials: C
authors.lastname: Hawkes
authors.forename: Mary
authors.initials: M
authors.lastname: Klote
authors.forename: George V
authors.initials: GV
authors.lastname: Ludwig
authors.forename: Glenn
authors.initials: G
authors.lastname: Wortmann
mesh_terms: D006801:Humans; D011446:Prospective Studies; D012899:Smallpox / Q000517:prevention & control* / Q000821:virology; D012900:Smallpox Vaccine / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D014616:Vaccinia virus / Q000276:immunology / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D012900:Smallpox Vaccine