title: STIR MRI to direct muscle biopsy in suspected idiopathic inflammatory myopathy.
abstract: Successful management of the idiopathic inflammatory myopathies requires an early and accurate diagnosis. The muscle biopsy remains the definitive test. However, false-negative biopsy results are common, as the disease is typically patchy in distribution. The advent of short tau inversion recovery sequences now allows rapid magnetic resonance imaging of the whole body to be performed, enabling identification of the muscles most suitable for biopsy. It also provides further diagnostic information through the form and anatomic distribution of the pathology. We report 2 cases illustrating the advantages of whole-body short tau inversion recovery magnetic resonance imaging before muscle biopsy. We encourage clinicians to use the technique in this context.
authors.affiliation: Department of Medicine, University of Otago School of Medicine, Dunedin Public Hospital, Dunedin, New Zealand. andrewconnor1974@hotmail.co.uk
authors.forename: Andrew
authors.initials: A
authors.lastname: Connor
authors.forename: Simon
authors.initials: S
authors.lastname: Stebbings
authors.forename: Noelyn
authors.initials: N
authors.lastname: Anne Hung
authors.forename: Graeme
authors.initials: G
authors.lastname: Hammond-Tooke
authors.forename: Grant
authors.initials: G
authors.lastname: Meikle
authors.forename: John
authors.initials: J
authors.lastname: Highton
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D018482:Muscle, Skeletal / Q000473:pathology*; D009220:Myositis / Q000175:diagnosis* / Q000188:drug therapy; D015203:Reproducibility of Results
chemical_list: D005938:Glucocorticoids