title: Prevalence of patent foramen ovale in patients with migraine.
abstract: Recent evidence supports that the prevalence of patent foramen ovale is higher in patients with migraine with aura. We conducted a case-control study and searched for intra-atrial right to left shunt in 53 patients with migraine. PFO was detected by means of transthoracic echocardiography with administration of contrast medium during valsalva maneuver and the results were compared with age and sex matched 27 healthy controls. Patent foramen ovale was more frequent in the migraine group (p<.01). The percentages of PFO in migraine patients with aura, without aura and the control group were 66.7%, 47.4% and 22.2%, respectively. Our results are supportive of an association between PFO and migraine, especially with aura.
authors.affiliation: Sişli Etfal Training and Research Hospital, Neurology Clinic, Istanbul, Turkey.
authors.forename: Asli Demirtaş
authors.initials: AD
authors.lastname: Tatlidede
authors.forename: Buket
authors.initials: B
authors.lastname: Oflazoğlu
authors.forename: Seden Erten
authors.initials: SE
authors.lastname: Celik
authors.forename: Ulker
authors.initials: U
authors.lastname: Anadol
authors.forename: Hulki
authors.initials: H
authors.lastname: Forta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D017548:Echocardiography, Transesophageal; D005260:Female; D054092:Foramen Ovale, Patent / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020325:Migraine with Aura / Q000150:complications*; D015995:Prevalence; D014421:Turkey / Q000453:epidemiology