title: Incidence and risk factors for non-nucleoside reverse transcriptase inhibitors (NNRTI)-related rash in Thai children with HIV infection.
abstract: The present study evaluated the incidence and risk factors that correlated with the development of non-nucleoside reverse transcriptase inhibitor (NNRTI) related rash in 69 Thai children followed prospectively. The overall incidence of NNRTI-related rash was 16% (22% for NVP and 4% for EFV rash). The only significant predictive factor that correlated with the development of NNRTI-related rash in a multivariate logistic regression model was a CD4% decrease at week 12.
authors.affiliation: Washington University, St. Louis, USA.
authors.forename: Sunitha
authors.initials: S
authors.lastname: Vemula
authors.forename: Stephen
authors.initials: S
authors.lastname: Kerr
authors.forename: Chitsanu
authors.initials: C
authors.lastname: Pancharoen
authors.forename: Arida
authors.initials: A
authors.lastname: Siripong
authors.forename: Pope
authors.initials: P
authors.lastname: Kosalaraksa
authors.forename: Chulapan
authors.initials: C
authors.lastname: Engchanil
authors.forename: Arpa
authors.initials: A
authors.lastname: Chuamchaitrakool
authors.forename: Jintana
authors.initials: J
authors.lastname: Intasan
authors.forename: Pagakrong
authors.initials: P
authors.lastname: Lumbiganond
authors.forename: Praphan
authors.initials: P
authors.lastname: Phanuphak
authors.forename: Jintanat
authors.initials: J
authors.lastname: Ananworanich
mesh_terms: D019380:Anti-HIV Agents / Q000009:adverse effects*; D044966:Anti-Retroviral Agents / Q000009:adverse effects; D018791:CD4 Lymphocyte Count; D002648:Child; D002675:Child, Preschool; D005076:Exanthema / Q000139:chemically induced* / Q000453:epidemiology / Q000209:etiology; D005260:Female; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors* / Q000187:drug effects; D006801:Humans; D008297:Male; D011446:Prospective Studies; D018894:Reverse Transcriptase Inhibitors / Q000009:adverse effects*; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents; D044966:Anti-Retroviral Agents; D018894:Reverse Transcriptase Inhibitors; C514824:reverse transcriptase, Human immunodeficiency virus 1; D054303:HIV Reverse Transcriptase