Synthesis and X-ray crystal structures of two transition metal complexes based on functionalised 1,5-anhydro-2-deoxy-D-galactitol and methyl 2-deoxy-alpha-D-galactopyranoside.
Two new ligands of transition metal cations based on galactose-derived scaffolds were synthesised: 1,5-anhydro-2-deoxy-3,4,6-tri-O-(2-picolyl)-D-galactitol and methyl 2-deoxy-3,4,6-tri-O-(2-picolyl)-alpha-D-galactopyranoside. These ligands permitted the isolation as single crystals of a Co(II) and a Ni(II) complex, respectively. The structures of both complexes were determined by X-ray crystallography showing a coordination sphere including sugar-bound oxygen atoms. The sugar-derived ligands were found to be in both cases in high energy conformations in the crystal structures of the complexes. These conformations contain an arrangement of sugar-bound oxygen atoms similar to those observed in polyol-metal and carbohydrate-metal complexes.
Cisnetti
Federico
F
Equipe de Chimie Bioorganique et Bioinorganique, ICMMO, UMR CNRS 8182, Université Paris-Sud 11, Bât. 420, 91405 Orsay, France.
Guillot
Régis
R
Ibrahim
Nada
N
Lambert
François
F
Thérisod
Michel
M
Policar
Clotilde
C
D002236:Carbohydrate Conformation; D003460:Crystallization; D018360:Crystallography, X-Ray; D003837:Deoxy Sugars; D004376:Galactitol / Q000737:chemistry*; D005690:Galactose / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D028561:Transition Elements
D003837:Deoxy Sugars; D008024:Ligands; D009942:Organometallic Compounds; D028561:Transition Elements; D004376:Galactitol; D005690:Galactose