title: Aging stability of complete blood count and white blood cell differential parameters analyzed by Abbott CELL-DYN Sapphire hematology analyzer.
abstract: This study presents the results of an aging stability study of complete blood count (CBC) and leukocyte differential parameters using the Abbott CELL-DYN Sapphire hematology analyzer. Stability studies showed no substantial change in CBC parameters up to 24-48 h at +23 +/- 2 degrees C (room temperature), except for optical platelet count (PLTo). For specimens aged over 24, the value of impedance platelet count yielded more reliable results than the routine PLTo. White blood cell (WBC) differential parameters, except eosinophils, were stable for up to 48 h at +23 +/- 2 degrees C. CBC parameters were stable for 72 h, except mean platelet volume, which slightly increased between 48 and 72 h, at +4 degrees C. WBC differentials were stable 48-72 h, with a slight decrease observed in absolute neutrophils and lymphocytes at +4 degrees C.
authors.affiliation: Department of Clinical Chemistry, Laboratory, Oulu University Hospital, University of Oulu, Oulu, Finland. pirjo.hedberg@ppshp.fi
authors.forename: P
authors.initials: P
authors.lastname: Hedberg
authors.forename: T
authors.initials: T
authors.lastname: Lehto
mesh_terms: D001322:Autoanalysis / Q000295:instrumentation / Q000379:methods*; D001772:Blood Cell Count / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007958:Leukocyte Count / Q000295:instrumentation / Q000379:methods*; D055550:Protein Stability; D015203:Reproducibility of Results; D013048:Specimen Handling; D013997:Time Factors