Temporal regulation of the first mitosis in Xenopus and mouse embryos.
Cell cycle regulation in Eukaryotes is based on common molecular actors and mechanisms. However, the canonical cell cycle is modified in certain cells. Such modifications play a key role in oocyte maturation and embryonic development. They can be achieved either by introduction of new components, pathways, substrates, changed interactions between them, or by elimination of some factors inherited by the cells from previous developmental stages. Here we discuss a particular temporal regulation of the first embryonic M-phase of Xenopus and mouse embryos. These two examples help to understand better the general regulation of M-phase of the cell cycle.
Kubiak
Jacek Z
JZ
CNRS/University of Rennes 1, Institute of Genetics & Development, UMR 6061, Mitosis & Meiosis Group, Faculty of Medicine, 2 Ave. Prof. Léon Bernard, CS 34317, 35043 Rennes Cedex, France. jacek.kubiak@univ-rennes1.fr
Chesnel
Franck
F
Richard-Parpaillon
Laurent
L
Bazile
Franck
F
Pascal
Aude
A
Polanski
Zbigniew
Z
Sikora-Polaczek
Marta
M
Maciejewska
Zuzanna
Z
Ciemerych
Maria A
MA
D000818:Animals; D002453:Cell Cycle / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D019926:Cyclin B / Q000502:physiology; D004622:Embryo, Mammalian / Q000502:physiology; D047108:Embryonic Development / Q000502:physiology*; D048049:Extracellular Signal-Regulated MAP Kinases / Q000502:physiology; D051379:Mice; D008938:Mitosis / Q000502:physiology*; D014981:Xenopus
D019926:Cyclin B; D048049:Extracellular Signal-Regulated MAP Kinases