title: Comparative antioxidant and cytotoxic effects of lignins from different sources.
abstract: The potential antioxidant activity of industrial lignins obtained from different sources and their potential cytotoxic effect on two immortalized cell lines is studied. In addition the stability of aqueous preparations of these lignins is studied together with the effect on them of ultraviolet irradiation. The lignins studied show a high antioxidant capacity over a range of concentrations that are not harmful to normal human cells. The stability of the lignin solutions when they are exposed to UVA light is confirmed. These findings suggest new uses for lignins in cosmetic and topical medical formulations. This study aims to demonstrate the antioxidant activity and stability of several lignins from different sources. It assesses their suitability for new commercial applications, mainly in cosmetics and pharmaceuticals, by discarding any possible cytotoxic properties.
authors.affiliation: Department of Physiology, Faculty of Pharmacy, Universitat de Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Ugartondo
authors.forename: Montserrat
authors.initials: M
authors.lastname: Mitjans
authors.forename: María Pilar
authors.initials: MP
authors.lastname: Vinardell
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002460:Cell Line; D003358:Cosmetics; D006801:Humans; D008031:Lignin / Q000494:pharmacology*; D051379:Mice; D014466:Ultraviolet Rays
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D008031:Lignin