Multi-target-directed ligands to combat neurodegenerative diseases.
Cavalli
Andrea
A
Department of Pharmaceutical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy. andrea.cavalli@unibo.it
Bolognesi
Maria Laura
ML
Minarini
Anna
A
Rosini
Michela
M
Tumiatti
Vincenzo
V
Recanatini
Maurizio
M
Melchiorre
Carlo
C
D000110:Acetylcholinesterase / Q000378:metabolism; D000544:Alzheimer Disease / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000378:metabolism; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D001665:Binding Sites; D002121:Calcium Channel Blockers / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D002614:Chelating Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D006816:Huntington Disease / Q000188:drug therapy / Q000378:metabolism; D008024:Ligands; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000378:metabolism; D019636:Neurodegenerative Diseases / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D016874:Neurofibrillary Tangles / Q000378:metabolism / Q000473:pathology; D018377:Neurotransmitter Agents / Q000378:metabolism; D010300:Parkinson Disease / Q000188:drug therapy / Q000378:metabolism; D058225:Plaque, Amyloid / Q000378:metabolism / Q000473:pathology
D016229:Amyloid beta-Peptides; D000975:Antioxidants; D002121:Calcium Channel Blockers; D002614:Chelating Agents; D002800:Cholinesterase Inhibitors; D008024:Ligands; D018377:Neurotransmitter Agents; D000110:Acetylcholinesterase