Cutaneous epithelioid hemangioendothelioma.
Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of endothelial cell origin. We describe an EHE arising on the plantar surface of the foot that was treated as verruca vulgaris for several years before a biopsy showed EHE. We discuss the clinical and histopathologic differential diagnoses for these tumors and review additional cases in which EHE has been mistaken for benign entities clinically.
Clarke
Loren E
LE
Department of Pathology, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA. lclarke@hmc.psu.edu
Lee
Robert
R
Militello
Giuseppe
G
Elenitsas
Rosalie
R
Junkins-Hopkins
Jacqueline
J
D003218:Condylomata Acuminata / Q000473:pathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005534:Foot Diseases / Q000473:pathology*; D005549:Foreign-Body Reaction / Q000473:pathology; D018323:Hemangioendothelioma, Epithelioid / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009463:Neuroma / Q000473:pathology; D012559:Schizophrenia / Q000473:pathology; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*; D019966:Substance-Related Disorders; D014008:Tinea Pedis / Q000473:pathology; D014860:Warts / Q000473:pathology