[A case of primary hepatic epithelioid hemangioendothelioma mimicking metastatic carcinoma].
Epithelioid hemangioendothelioma is a rare vascular origin tumor which usually occurs in soft tissues, liver, and lung. It usually affects adult women and presents as multiple hepatic nodules with mainly peripheral distribution. It is difficult to diagnose and treat because of non-specific clinical manifestations and findings on the imaging study. Moreover, pathological misdiagnosis is common. We report a case of this rare tumor that was detected incidentally. Final diagnosis was based on histological evidence. A 52-years old man suffered from right upper quadrant abdominal pain for 3 months, and was initially misdiagnosed as a metastatic carcinoma. Physical examination revealed superior cervical lymphadenopathy with mild hepatomegaly. Finally, hepatic epithelioid hemangioendothelioma was diagnosed on the basis of positive immunohistochemical staining for factor VIII, CD34, and VEGF. Our case highlights the importance of a histological diagnosis to avoid misdiagnosis.
Kim
Sang Gi
SG
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Jung
Min Kyu
MK
Jeon
Seong Woo
SW
Cho
Chang Min
CM
Tak
Won Young
WY
Kweon
Young Oh
YO
Kim
Sung Kook
SK
Choi
Yong Hwan
YH
D018952:Antigens, CD34 / Q000032:analysis / Q000276:immunology; D002277:Carcinoma / Q000556:secondary; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography
D018952:Antigens, CD34; D005169:Factor VIII