title: Molecular mechanisms of cerebral vasospasm following aneurysmal SAH.
abstract: Cerebral vasospasm following aneurysmal vasospasm has been the subject of intensive research. However the underlying pathophysiological mechanisms remain obscure. This article should summarize the present state concerning smooth muscle contraction, endothelial dysfunction, inflammatory changes, gene expression, in the genesis of vasospasm following aneurysmal subarachnoid hemorrhage.
authors.affiliation: Department of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. ralf.rothoerl@lrz.tum.de
authors.forename: Ralf Dirk
authors.initials: RD
authors.lastname: Rothoerl
authors.forename: Florian
authors.initials: F
authors.lastname: Ringel
mesh_terms: D000818:Animals; D002536:Cerebral Arteries / Q000378:metabolism / Q000503:physiopathology*; D042783:Endothelial Cells / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology; D018836:Inflammation Mediators / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000378:metabolism / Q000503:physiopathology*; D015398:Signal Transduction / Q000502:physiology; D013345:Subarachnoid Hemorrhage / Q000150:complications*; D020301:Vasospasm, Intracranial / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*
chemical_list: D018836:Inflammation Mediators