title: A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma.
abstract: BACKGROUND
  A 39-year-old man presented with a 2-month history of abdominal pain, jaundice, non-bloody diarrhea, weakness, and weight loss. Initial evaluation revealed intrahepatic ductopenia consistent with vanishing bile duct syndrome and IBD, type unclassified. Although treatment with budesonide improved his symptoms, they worsened several months later. On repeat evaluation, he was found to have extensive lymphadenopathy and an elevated white blood cell count.
  
  
  METHODS
  Physical examination, laboratory investigations, abdominal ultrasound, CT scans, magnetic resonance cholangiopancreatography, endoscopic retrograde cholangiopancreatography, colonoscopies with biopsies, hepatic biopsy, axillary lymph node biopsy.
  
  
  METHODS
  Hodgkin's lymphoma with secondary vanishing bile duct syndrome and IBD, type unclassified.
  
  
  RESULTS
  The initial symptoms were managed with budesonide, but following recurrence, the patient's underlying lymphoma was treated with nitrogen mustard and dexamethasone.
authors.affiliation: Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan 48109-0368, USA. adebened@med.umich.edu
authors.forename: Anthony T
authors.initials: AT
authors.lastname: DeBenedet
authors.forename: Carl L
authors.initials: CL
authors.lastname: Berg
authors.forename: Kyle B
authors.initials: KB
authors.lastname: Enfield
authors.forename: Randall L
authors.initials: RL
authors.lastname: Woodford
authors.forename: Audrey K
authors.initials: AK
authors.lastname: Bennett
authors.forename: Patrick G
authors.initials: PG
authors.lastname: Northup
mesh_terms: D000328:Adult; D001649:Bile Duct Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D013577:Syndrome