title: Clinical and angiographic results after implantation of a passive-coated coronary stent in patients with acute myocardial infarction.
abstract: BACKGROUND
  Key insights into the role of platelets in acute myocardial infarction (AMI) and unstable angina have led to the development of the polymer-coated stent, Camouflage(R). Coating of stents is an elegant method to minimize interactions between platelets and the stent surface and the vascular response following stent implantation.
  
  
  METHODS
  This single-center prospective registry was performed to estimate the in-hospital, 30-day and 180-day event rate (death, revascularization, reinfarction and pathological stress test at 180 days) in an everyday patient population with AMI with immediate percutaneous coronary intervention. There were 44 males (65.7%) and 23 females (34.3%); 53 patients (79.1%) had hypertension, 11 (16.4%) were diabetic, and 32 (47.8%) had elevated LDL cholesterol. The mean age was 60.7 +/- 11.6 years.
  
  
  RESULTS
  Sixty-seven patients with AMI (STEMI: 56.7%, NSTEMI: 43.3%) were included. Clinical data at the 30-day and 180-day follow up were available for all but 1 of the patients. Overall, there were 3 (4.5%) deaths, 1 (1.5%) death at 30 days and 2 (3.0%) at 180 days (1 cardiogenic shock 3, 1 sudden cardiac death and 1 AMI). Three (4.5%) patients experienced subacute closure of the target vessel. At 180 days, 1 (1.5%) patient had a pathological stress test and 5 patients (7.5%) underwent target vessel revascularization.
  
  
  CONCLUSIONS
  The registry with this passive-coated stent showed good results in patients with AMI, consistent with earlier studies. Data are now available both for the development of hypotheses and for a data-based estimation of the number of cases for a comparative clinical study versus other coronary stents.
authors.affiliation: Volklingen Heart Center, Chief, Internal Medicine Clinic I, Richardstrasse 5-9 , Volklingen, 66333, Germany. oezbek@ihkf.de
authors.forename: Cem
authors.initials: C
authors.lastname: Ozbek
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Bay
authors.forename: Lorenz
authors.initials: L
authors.lastname: Jochum
authors.forename: Friedrich
authors.initials: F
authors.lastname: Jung
authors.forename: Roland
authors.initials: R
authors.lastname: Bach
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000401:mortality / Q000628:therapy*; D011108:Polymers / Q000494:pharmacology; D011446:Prospective Studies; D012042:Registries; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D015607:Stents; D016019:Survival Analysis; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D020099:Coated Materials, Biocompatible; D011108:Polymers