title: Decrease in the frequency of meningeal involvement in AIDS-related systemic lymphoma in patients receiving HAART.
abstract: We evaluated the frequency of primary central nervous system lymphoma and leptomeningeal involvement in systemic non-Hodgkin's lymphoma (NHL) in HIV-infected patients. Those receiving highly active antiretroviral therapy (HAART) showed a decrease in leptomeningeal involvement in systemic NHL (0/30 vs. 12/87; p=0.023). Therefore HAART could prevent CNS involvement in systemic NHL.
authors.forename: José-Tomás
authors.initials: JT
authors.lastname: Navarro
authors.forename: Ferran
authors.initials: F
authors.lastname: Vall-Llovera
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Mate
authors.forename: Mireia
authors.initials: M
authors.lastname: Morgades
authors.forename: Evarist
authors.initials: E
authors.lastname: Feliu
authors.forename: Josep-Maria
authors.initials: JM
authors.lastname: Ribera
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018450:Disease Progression; D005260:Female; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000517:prevention & control*; D008297:Male; D008578:Meninges / Q000473:pathology*; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors