Case of unilateral focal dermal hypoplasia (Goltz syndrome).
Focal dermal hypoplasia (FDH) is a rare multisystem condition in which developmental defects of the skin are associated with ocular, dental and skeletal abnormalities. Herein, we report an 8-year-old girl with FDH. Her body halves were asymmetric and she had linear cutaneous atrophy with yellow nodules on her extremities. Syndactylies of the third and fourth fingers of the right hand and second and third toes of the right foot were also observed. Histological examination revealed dermal hypoplasia and upward extension of the adipose tissue. Based on these observations, she was diagnosed with unilateral FDH.
Aoyama
Masako
M
Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. ccb41800@nyc.odn.ne.jp
Sawada
Hiroo
H
Shintani
Yoichi
Y
Isomura
Iwao
I
Morita
Akimichi
A
D002648:Child; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000235:genetics / Q000473:pathology*; D006801:Humans; D009030:Mosaicism; D012867:Skin / Q000473:pathology*; D050151:Subcutaneous Fat / Q000473:pathology*; D013576:Syndactyly / Q000473:pathology