title: Disseminated Mycobacterium avium-intracellulare infection in a person with AIDS with cutaneous and CNS lesions.
abstract: We present the case of a 55-year-old-man with AIDS who had disseminated Mycobacterium avium-intracellulare (MAI) infection who was nonadherent to antiretroviral treatment and prophylaxis for opportunistic infections. The patient acquired HIV via intravenous drug sue; he had a CD4+ cell count of 4/microL (1%) and an HIV RNA level of 114,000 copies/mL at the time of his HIV diagnosis. He presented with MAI bacteremia and had rapidly evolving and resolving cutaneous lesions caused by MAI. Concomitant nonspecific brain lesions presented a diagnostic challenge, but they improved with MAI treatment. In persons with HIV/AIDS who have cutaneous lesions, biopsy of superficial lesions has proved helpful. MAI infection should be considered in the differential diagnosis of cutaneous and brain lesions in persons with HIV/AIDS.
authors.affiliation: Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
authors.forename: Richa
authors.initials: R
authors.lastname: Tandon
authors.forename: Kye S
authors.initials: KS
authors.lastname: Kim
authors.forename: Richard
authors.initials: R
authors.lastname: Serrao
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000134:cerebrospinal fluid / Q000635:transmission*; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000209:etiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex / Q000472:pathogenicity; D015270:Mycobacterium avium-intracellulare Infection / Q000134:cerebrospinal fluid / Q000635:transmission*; D012367:RNA, Viral / Q000097:blood*; D012883:Skin Ulcer / Q000209:etiology* / Q000473:pathology
chemical_list: D044966:Anti-Retroviral Agents; D012367:RNA, Viral