title: Sequencing and alignment of mitochondrial genomes of Tibetan chicken and two lowland chicken breeds.
abstract: Tibetan chicken lives in high-altitude area and has adapted well to hypoxia genetically. Shouguang chicken and Silky chicken are both lowland chicken breeds. In the present study, the complete mitochondrial genome sequences of the three chicken breeds were all sequenced. The results showed that the mitochondrial DNAs (mtDNAs) of Shouguang chicken and Silky chicken consist of 16784 bp and 16785 bp respectively, and Tibetan chicken mitochondrial genome varies from 16784 bp to 16786 bp. After sequence analysis, 120 mutations, including 4 single nucleotide polymorphisms (SNPs) in tRNA genes, 9 SNPs and 1 insertion in rRNA genes, 38 SNPs and 1 deletion in D-LOOP, 66 SNPs in protein-coding genes, were found. This work will provide clues for the future study on the association between mitochondrial genes and the adaptation to hypoxia.
authors.affiliation: College of Animal Science and Technology, China Agricultural University, Beijing 100094, China.
authors.forename: HaiGang
authors.initials: H
authors.lastname: Bao
authors.forename: ChunJiang
authors.initials: C
authors.lastname: Zhao
authors.forename: JunYing
authors.initials: J
authors.lastname: Li
authors.forename: ChangXin
authors.initials: C
authors.lastname: Wu
mesh_terms: D000818:Animals; D001483:Base Sequence; D002645:Chickens / Q000235:genetics*; D054629:Genome, Mitochondrial / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D016415:Sequence Alignment; D018609:Tibet
chemical_list: D012335:RNA, Ribosomal; D012343:RNA, Transfer