[Prognosis of metabolic syndrome in coronary artery disease patients of different genders].
OBJECTIVE
To analyze the prevalence and characteristics of metabolic syndrome (MS) in the patients with coronary artery disease (CAD) of different genders who underwent revascularization.


METHODS
The clinical data of 2596 patients in the DESIRE (Drug-eluting Stent Impact on Revascularization) study who underwent percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) were analyzed and the patients were followed up till death. MS was diagnosed based on the Chinese standard (modified ATP III).


RESULTS
The mean follow-up time was 828.8 +/- 373.2 days. 1139 of the 2596 patients were diagnosed as with MS. The prevalence of MS in the female patients was 50.9%, significantly higher than that in the male patients (41.8%, P < 0.0001). Complication of MS was the only predictive factor of poor prognosis in female CAD patients (OR = 2.019, 95% CI = 1.751 - 2.506, P = 0.023). Fasting blood glucose >or= 110 mg/dl was responsible for most of the increased risk associated with MS (adjusted OR 2.511, 95% CI 1.396 approximately 4.511, P = 0.002).


CONCLUSIONS
In comparison with the male patients the female patients undergoing revascularization have a higher he prevalence of MS and worse prognosis. In the 4 elements of MS hyperglycemia is directly associated with prognosis.
Hu
Rong
R
Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China.
Ma
Chang-sheng
CS
Nie
Shao-ping
SP
Lü
Qiang
Q
Kang
Jun-ping
JP
DU
Xin
X
Zhang
Ying
Y
Gao
Ying-chun
YC
He
Li-qun
LQ
Jia
Chang-qi
CQ
Liu
Xin-min
XM
Dong
Jian-zeng
JZ
Liu
Xiao-hui
XH
Chen
Fang
F
Zhou
Yu-jie
YJ
Lü
Shu-zheng
SZ
Wu
Xue-si
XS
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002681:China / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000150:complications* / Q000378:metabolism / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008659:Metabolic Diseases / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012737:Sex Factors; D015607:Stents; D016019:Survival Analysis; D013577:Syndrome