title: Retinal vessel diameter in normal and glaucomatous eyes: the Beijing eye study.
abstract: OBJECTIVE
  To assess retinal vessel diameter in adult Chinese with and without glaucoma.
  
  
  METHODS
  The population-based, cross-sectional study included 4439 of the 5324 subjects asked to participate (response rate 83.4%), all aged 40 years or older. This study was divided into a rural part (1973 subjects [44.4%]) and an urban part (2466 subjects [55.6%]). Colour optic disc and fundus photographs were morphometrically examined for 2418 subjects. The retinal vessel diameters were measured at the optic disc border and at a distance of 2 mm to the optic disc border. The main outcome measure was the retinal vessel diameter.
  
  
  RESULTS
  Diameters of the retinal arteries were significantly (P < 0.001) the widest in the temporal inferior region, followed by the temporal superior region (P < 0.001), the nasal superior region (P < 0.001) and finally the nasal inferior region. Except for the nasal inferior vein, the same held true for the retinal veins. The sequence of the main four vessel trunks with respect to their diameters was not associated with age, gender or hyperopia versus myopia. The artery diameters showed a tendency to decrease in older age, while the vein diameters decreased across all age groups. Eyes with glaucomatous optic nerve damage showed significantly (P < 0.001) thinner arteries while the retinal vein diameters were not different.
  
  
  CONCLUSIONS
  Diameters of the retinal arterioles and veins are the widest in the temporal inferior arcade, followed by the temporal superior arcade, the nasal superior arcade and finally the nasal inferior arcade. Retinal artery diameters decrease with glaucoma, and retinal vein diameters decrease with age.
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Yunshong
authors.initials: Y
authors.lastname: Wang
authors.forename: Yaxing
authors.initials: Y
authors.lastname: Wang
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005654:Fundus Oculi; D005901:Glaucoma / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D012161:Retinal Artery / Q000473:pathology*; D012169:Retinal Vein / Q000473:pathology*