title: Necrotizing enterocolitis and death in a goat kid associated with enterotoxin (CPE)-producing Clostridium perfringens type A.
abstract: A goat kid died after being depressed for several days. No significant gross abnormalities were observed at postmortem examination, while histopathological analysis revealed diffuse necrotizing enterocolitis. Isolation of Clostridium perfringens type A secreting enterotoxin (CPE) and presence of CPE in the small intestine suggest that CPE contributed to the death of this kid.
authors.affiliation: California Animal Health and Food Safety Laboratory System, University of California-Davis, San Bernardino Branch, Calfornia 92408, USA.
authors.forename: Mariano E Fernandez
authors.initials: ME
authors.lastname: Miyakawa
authors.forename: Julian
authors.initials: J
authors.lastname: Saputo
authors.forename: Judy St
authors.initials: JS
authors.lastname: Leger
authors.forename: Birgit
authors.initials: B
authors.lastname: Puschner
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Fisher
authors.forename: Bruce A
authors.initials: BA
authors.lastname: McClane
authors.forename: Francisco A
authors.initials: FA
authors.lastname: Uzal
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D003015:Clostridium Infections / Q000473:pathology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification* / Q000378:metabolism; D020345:Enterocolitis, Necrotizing / Q000473:pathology / Q000662:veterinary*; D004768:Enterotoxins / Q000096:biosynthesis*; D017809:Fatal Outcome; D015511:Goat Diseases / Q000473:pathology*; D006041:Goats; D008297:Male
chemical_list: D004768:Enterotoxins; C035598:enterotoxin, Clostridium