title: Bisphosphonate-related osteonecrosis of the jaws (ONJ): a report of two cases.
abstract: Osteonecrosis of thejaw (ONJ) is strongly associated with the use of aminobisphosphonates. Herein, the authors report two cases of ONJ after intravenous bisphosphonate therapy including clinical presentations, X-ray, and pathological findings. Since there is no definite treatment for ONJ, the focus should be on prevention with a dental evaluation for all patients before starting bisphosphonates.
authors.affiliation: Department of Medicine, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. pchatl@kku.ac.th
authors.forename: Chatlert
authors.initials: C
authors.lastname: Pongchaiyakul
authors.forename: Krittinant
authors.initials: K
authors.lastname: Auraiwan
authors.forename: Praew
authors.initials: P
authors.lastname: Kotruchin
authors.forename: Churairat
authors.initials: C
authors.lastname: Kularbkaew
mesh_terms: D000328:Adult; D004164:Diphosphonates / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007568:Jaw / Q000187:drug effects / Q000473:pathology*; D008297:Male; D008334:Mandible / Q000187:drug effects / Q000473:pathology*; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced*
chemical_list: D004164:Diphosphonates