Visceral fat and total body fat mass correlate differently with hormones in rat.
Forty-eight 67-day-old male Wistar rats (330+/-5g) were fed ad libitum either with a lipid enriched diet or a standard laboratory chow. Half of each sub-group was submitted to training. Training and difference in diet composition induced nonsignificant changes in body adiposity. Visceral fat (perirenal adipose tissue mass) was correlated with leptin (r=0.35, p=0.02) and insulin (r=0.38, p=0.01). Total body fat mass (measured by DEXA) was correlated with leptin only (r=0.58, p=0.003). Other correlations between perirenal adipose tissue or fat mass and adiponectin or insulin like growth factor 1 were nonsignificant. These results suggest that, in rat like in human, visceral fat development is linked with insulin insensitivity.
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Biologie des activités physiques et sportives (BAPS), laboratoire biologie B, Les Cézeaux, 63177 Aubière cedex, France. edmond57@caramail.com
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Michaux
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D052242:Adiponectin / Q000097:blood; D000273:Adipose Tissue / Q000033:anatomy & histology / Q000473:pathology*; D000818:Animals; D001835:Body Weight; D004041:Dietary Fats / Q000009:adverse effects; D006949:Hyperlipidemias / Q000139:chemically induced / Q000473:pathology; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D050152:Intra-Abdominal Fat / Q000033:anatomy & histology / Q000473:pathology*; D020738:Leptin / Q000097:blood*; D008297:Male; D009929:Organ Size; D010805:Physical Conditioning, Animal; D051381:Rats; D017208:Rats, Wistar / Q000033:anatomy & histology / Q000097:blood / Q000502:physiology*
D052242:Adiponectin; C499920:Adipoq protein, rat; D004041:Dietary Fats; D007328:Insulin; D020738:Leptin; D007334:Insulin-Like Growth Factor I