Polyglandular autoimmunity with macrophagic myofasciitis.
We report a man with chronic fatigue, multiple autoimmune disorders, and a muscle biopsy consistent with macrophagic myofasciitis. This rare and recently described muscle disorder is seen in patients exposed to vaccinations with aluminum hydroxide adjuvant. This case highlights the relationship between macrophagic myofasciitis and autoimmunity.
Theeler
Brett J
BJ
Department of Neurology, Madigan Army Medical Center, 9040A Fitzsimmons Dr., Tacoma, WA 98431, USA. btheeler@hotmail.com
Simper
Novae B
NB
Ney
John P
JP
D000276:Adjuvants, Immunologic / Q000009:adverse effects; D000328:Adult; D000536:Aluminum Hydroxide / Q000009:adverse effects; D005208:Fasciitis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008264:Macrophages / Q000473:pathology*; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology*; D009220:Myositis / Q000209:etiology* / Q000276:immunology; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications* / Q000473:pathology
D000276:Adjuvants, Immunologic; D000536:Aluminum Hydroxide