title: Cathepsin E: a mini review.
abstract: Cathepsin E is a major intracellular aspartic protease which is predominantly present in the cells of immune system and is frequently implicated in antigen processing via the MHC class II pathway. In the present review some of the known features of cathepsin E such as tissue distribution, subcellular localization, enzymatic properties, intracellular trafficking, gene regulation and associated physiological conditions are highlighted.
authors.affiliation: Medical and Natural Sciences Research Centre, University of Tübingen, Ob dem Himmelreich 7, 72074 Tuebingen, Germany.
authors.forename: Nousheen
authors.initials: N
authors.lastname: Zaidi
authors.forename: Hubert
authors.initials: H
authors.lastname: Kalbacher
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000502:physiology; D020059:Cathepsin E / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D004790:Enzyme Induction / Q000502:physiology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D009928:Organ Specificity / Q000502:physiology; D011499:Protein Processing, Post-Translational; D013379:Substrate Specificity / Q000502:physiology
chemical_list: D004791:Enzyme Inhibitors; D020059:Cathepsin E