title: [Development of on-line sample preparation coupled with liquid chromatography-mass spectrometry for analysis of small molecules in biofluids].
abstract: On-line liquid chromatography-mass spectrometry (LC-MS) is a highly sensitive, highly selective and high throughput method for the analysis of small molecules in biofluids. The developments, characterizations and applications of pre-column, on-line LC-MS method and its configuration in the recent five years are reviewed.
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, the Chinese Academy of Sciences, Beijing 100085, China. sundy6670@163.com
authors.forename: Min
authors.initials: M
authors.lastname: Liu
authors.forename: Lixia
authors.initials: L
authors.lastname: Zhao
authors.forename: Baoyuan
authors.initials: B
authors.lastname: Guo
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Lin
mesh_terms: D000818:Animals; D002853:Chromatography, Liquid / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*