title: Neuropsychological results in pediatric patients with epilepsy surgery in the parietal cortex.
abstract: This study evaluated pre- and postoperatively cognitive functions in 15 pediatric patients with surgically treated parietal lobe epilepsy (PLE). Seizure outcome was very satisfying with 87% seizure-free patients 1 year after surgery, and 82% in the long-term follow-up. Preoperative intelligence was in the subaverage range. Impairments in specific cognitive functions (memory, attention, executive functions) were evident preoperatively for 39-66% of patients. Behavioral disorders were rare. No side differences (left versus right PLE) were indicated pre- or postoperatively. Postoperative improvements were found in behavior and attention; other cognitive functions were unchanged. All in all, this preliminary study indicated a satisfactory neuropsychological outcome in pediatric patients with PLE.
authors.affiliation: Department of Epileptology, University of Bonn, Bonn, Germany. ulrike.gleissner@ukb.uni-bonn.de
authors.forename: Ulrike
authors.initials: U
authors.lastname: Gleissner
authors.forename: Stefan
authors.initials: S
authors.lastname: Kuczaty
authors.forename: Hans
authors.initials: H
authors.lastname: Clusmann
authors.forename: Christian E
authors.initials: CE
authors.lastname: Elger
authors.forename: Christoph
authors.initials: C
authors.lastname: Helmstaedter
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis* / Q000503:physiopathology; D018572:Disease-Free Survival; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007361:Intelligence Tests / Q000706:statistics & numerical data; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D017063:Outcome Assessment, Health Care; D010296:Parietal Lobe / Q000503:physiopathology*; D011300:Preoperative Care; D016896:Treatment Outcome