title: Next-generation sequencing transforms today's biology.
abstract: A new generation of non-Sanger-based sequencing technologies has delivered on its promise of sequencing DNA at unprecedented speed, thereby enabling impressive scientific achievements and novel biological applications. However, before stepping into the limelight, next-generation sequencing had to overcome the inertia of a field that relied on Sanger-sequencing for 30 years.
authors.affiliation: Pennsylvania State University, Center for Comparative Genomics and Bioinformatics, 310 Wartik Building, University Park, Pennsylvania 16802, USA. scs@bx.psu.edu
authors.forename: Stephan C
authors.initials: SC
authors.lastname: Schuster
mesh_terms: D000465:Algorithms; D001695:Biology / Q000639:trends*; D005544:Forecasting; D020411:Oligonucleotide Array Sequence Analysis / Q000639:trends*; D017422:Sequence Analysis, DNA / Q000639:trends*