[Treatment and results of therapy in autoimmune hemolytic anemia].
Basic principles in the therapy of idiopathic autoimmune hemolytic anemia induced by warm antibody were glucocorticoides and splenectomy. Immunosupresive drugs, plasmaferesis and intravenous high doses gamma globulin therapy are also useful. In secundary autoimmune hemolytic anemia induced by warm antibody we treated basic illness. During the period of 1990-1992 we treated 21 patients with primary autoimmune hemolytic anemia and 6 patients with secondary /4 CLL and 2 Non-Hodgkin's lymphoma/. Complete remission we found as a normalisation of reticulocites and hemoglobin level respectively. Complete remission by corticoides we got in 14/21 patients, partial response in 2/21 respectively. Complete response by splenectomy we got in 2/3 splenoctomized patients (idiopathic type). For successful treatment secondary hemolytic anemias we treated primary diseases (CLL and malignant lymphoma) and we got in 4/6 patients complete remission. Our results were standard in both type of autoimmune hemolytic anaemias induced by warm antibody.
Tasić
J
J
Macukanović
L
L
Pavlović
M
M
Koraćević
S
S
Govedarević
N
N
Kitić
Lj
Lj
Tijanić
I
I
Bakić
M
M
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged