Multiwalled carbon nanotube-doxorubicin supramolecular complexes for cancer therapeutics.
Multiwalled carbon nanotube aqueous dispersions using block copolymers are able to form supramolecular complexes with the aromatic chromophore and anticancer agent doxorubicin via pi-pi stacking and enhance its cytotoxic activity.
Ali-Boucetta
Hanene
H
Nanomedicine Laboratory, Centre for Drug Delivery, The School of Pharmacy, University of London, London, UK.
Al-Jamal
Khuloud T
KT
McCarthy
David
D
Prato
Maurizio
M
Bianco
Alberto
A
Kostarelos
Kostas
K
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology*; D004317:Doxorubicin / Q000627:therapeutic use*; D006801:Humans; D046529:Microscopy, Electron, Transmission; D037742:Nanotubes, Carbon; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D037742:Nanotubes, Carbon; D004317:Doxorubicin