title: Rituximab in the treatment of primary bilateral adrenal lymphoma with adrenal crisis.
abstract: Primary adrenal lymphoma (PAL) is a rare extranodal non-Hodgkin's lymphoma. The majority of the patients are elderly men with bilateral adrenal involvements. The optimal treatment of PAL has not been well established currently. We herein report on a patient with primary bilateral adrenal lymphoma and adrenal crisis that treated with rituximab. Our case does demonstrate that rituximab could be administered without significant toxicities, and resulted in clinical improvement with disease stabilization in this critically ill patient.
authors.affiliation: Division of Hematology and Oncology, Department of Internal Medicine, Mackay Memorial Hospital, 92, Section 2, Chung Shan North Road, Taipei, 104, Taiwan.
authors.forename: Ken-Hong
authors.initials: KH
authors.lastname: Lim
authors.forename: Tzeun-Yuh
authors.initials: TY
authors.lastname: Chiou
authors.forename: Cheng-Jui
authors.initials: CJ
authors.lastname: Lin
authors.forename: Ruey-Kuen
authors.initials: RK
authors.lastname: Hsieh
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000188:drug therapy*; D000309:Adrenal Insufficiency / Q000209:etiology*; D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000627:therapeutic use*; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage; D000069283:Rituximab; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone