title: Oncocytoma in the mandibular salivary gland of a cat.
abstract: A cat was referred for investigation of a soft tissue mass caudal to the left mandible. Initial investigations suggested a malignant salivary gland tumour, and the mass was removed by extracapsular resection of the mandibular gland. Histopathology showed an oncocytoma within the salivary gland. An oncocytoma is a neoplastic transformation of oncocytes. Oncocytes are cells with a small nucleus and intense eosinophilic granular cytoplasm due to numerous mitochondria, which proliferate during ageing in exocrine and endocrine glandular tissues. Physiological proliferation occurs next to oncocytosis, oncocytoma, and oncocytic carcinoma. This is the first report of an oncocytoma in a feline mandibular salivary gland, and the first report of long-term survival after surgical removal.
authors.affiliation: b.a.w.brocks@vet.uu.nl <b.a.w.brocks@vet.uu.nl>
authors.forename: Bouvien A
authors.initials: BA
authors.lastname: Brocks
authors.forename: Marijke E
authors.initials: ME
authors.lastname: Peeters
authors.forename: Simon
authors.initials: S
authors.lastname: Kimpfler
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000601:surgery; D002415:Cats; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome