title: Imaging findings of upper abdominal involvement by acute megakaryoblastic leukaemia.
abstract: Acute megakaryoblastic leukaemia (AMKL), a relatively rare type of acute myeloid leukaemia, is characterized by frequent involvement of the liver, spleen and lymph nodes in addition to myelofibrosis in children. Diagnosis is difficult both clinically and pathologically, and the hepatic or lymph node involvement is not uncommonly misinterpreted as solid tumour. We report the imaging findings of upper abdominal involvement by AMKL in an infant. The hepatic lesion, initially suspected to be hepatoblastoma, showed a distinctive appearance on MRI suggesting its infiltrative nature. With the association of splenic lesion and lymphadenopathy, the imaging findings were considered indicative of a haematological disorder.
authors.affiliation: Department of Radiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. amemiya-tky@umin.ac.jp
authors.forename: Shiori
authors.initials: S
authors.lastname: Amemiya
authors.forename: Masaaki
authors.initials: M
authors.lastname: Akahane
authors.forename: Junko
authors.initials: J
authors.lastname: Takita
authors.forename: Takashi
authors.initials: T
authors.lastname: Igarashi
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
mesh_terms: D003287:Contrast Media; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007947:Leukemia, Megakaryoblastic, Acute / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media