Application of tissue microarrays in placental research.
A complementary tool to gene-based arrays are tissue microarrays, which allow the validation of DNA/RNA-derived profiling results on the protein level and offer the possibility of exact location within the tissue structures. Here we describe the technical details of the application of tissue microarray in placental research. Although the placenta represents a very inhomogeneous organ, this technique is also usable in placental research.
Horn
Lars-Christian
LC
Division of Gynecologic and Perintatal Pathology, Institute of Pathology, University of Leipzig, D-04103 Leipzig, Germany. hornl@medizin.uni-leipzig.de
Purz
Sandra
S
Leo
Cornelia
C
Stepan
Holger
H
D000328:Adult; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D010920:Placenta / Q000473:pathology*; D010922:Placenta Diseases / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D011247:Pregnancy; D046888:Tissue Array Analysis / Q000379:methods*