title: Vincristine-induced peripheral neuropathy and urinary bladder paralysis in a child with rhabdomyosarcoma.
abstract: Vincristine commonly induces peripheral neuropathy but rarely causes voiding dysfunction. In this report, we describe a case of neurogenic bladder and peripheral neuropathy caused by the neurotoxic effect of vincristine and documented by urodynamic testing and electromyography. Neurologic evaluation aided in monitoring and understanding this problem.
authors.affiliation: Department of Pediatric Oncology, Gazi University Faculty of Medicine, Besevler, Ankara, Turkey. caglarcitak@yahoo.com
authors.forename: Elvan Caglar
authors.initials: EC
authors.lastname: Citak
authors.forename: Aynur
authors.initials: A
authors.lastname: Oguz
authors.forename: Ceyda
authors.initials: C
authors.lastname: Karadeniz
authors.forename: Belgin
authors.initials: B
authors.lastname: Karaoglan
authors.forename: Mustafa Ozgur
authors.initials: MO
authors.lastname: Tan
authors.forename: Visal
authors.initials: V
authors.lastname: Okur
authors.forename: Ali
authors.initials: A
authors.lastname: Cansu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D003609:Dactinomycin / Q000008:administration & dosage / Q000009:adverse effects; D004576:Electromyography; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D010243:Paralysis / Q000139:chemically induced*; D012208:Rhabdomyosarcoma / Q000150:complications* / Q000188:drug therapy; D001750:Urinary Bladder, Neurogenic / Q000139:chemically induced*; D014563:Urodynamics; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide