title: Copper-catalyzed aerobic oxidative amidation of terminal alkynes: efficient synthesis of ynamides.
abstract: A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles.
authors.affiliation: Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Hamada
authors.forename: Xuan
authors.initials: X
authors.lastname: Ye
authors.forename: Shannon S
authors.initials: SS
authors.lastname: Stahl
mesh_terms: D000332:Aerobiosis; D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000480:Alkynes; D000577:Amides; D003300:Copper