Molecular diversity at the plant-pathogen interface.
Plants have evolved a robust innate immune system that exhibits striking similarities as well as significant differences with various metazoan innate immune systems. For example, plants are capable of perceiving pathogen-associated molecular patterns through pattern recognition receptors that bear structural similarities to animal Toll-like receptors. In addition, plants have evolved a second surveillance system based on cytoplasmic "NB-LRR" proteins (nucleotide-binding, leucine-rich repeat) that are structurally similar to animal nucleotide-binding and oligomerization domain (NOD)-like receptors. Plant NB-LRR proteins do not detect PAMPs; rather, they perceive effector proteins that pathogens secrete into plant cells to promote virulence. This review summarizes the current state of knowledge about the molecular functionality and evolution of these immune surveillance genes.
McDowell
John M
JM
Department of Plant Pathology, Physiology, and Weed Science, Latham Hall, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0390, USA. johnmcd@vt.edu
Simon
Stacey A
SA
D000818:Animals; D019143:Evolution, Molecular; D017353:Gene Deletion; D054884:Host-Pathogen Interactions; D010935:Plant Diseases / Q000276:immunology; D010940:Plant Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000276:immunology* / Q000378:metabolism*
D010940:Plant Proteins