Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma.
OBJECTIVE
To assess the efficacy of percutaneous cementoplasty for painful bone metastasis from hepatocellular carcinoma (HCC).


METHODS
Cementoplasty was performed for 22 metastatic bone tumors in 13 patients. All patients had intractable pain and were diagnosed as metastatic bone tumor from HCC. The ostyneedle was inserted in the center of the site of bone metastasis under CT guidance. VAS score, Tokuhashi score and Frankel score were used for assessment of the efficacy of cementoplasty. We also assessed the response to treatment, adverse events and prognosis.


RESULTS
Only the VAS score, but not Tokuhashi and Frankel scores, improved after cementoplasty. Cementoplasty for painful bone metastasis provided relief of severe pain but did not improve prognosis, neurological function or survival. Eleven of 13 (85%) patients showed CR or PR and the mean pain-free period was 5 months, including a 10-month pain-free period in one case. No major complications were encountered.


CONCLUSIONS
Percutaneous cementoplasty can provide pain relief and improvement of quality of life, though without survival benefits, for HCC patients with painful bone metastasis.
Kodama
Hideaki
H
Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Science, Hiroshima University, Minami-ku, Hiroshima, Japan.
Aikata
Hiroshi
H
Uka
Kiminori
K
Takaki
Shintaro
S
Mori
Nami
N
Waki
Koji
K
Jeong
Soo Cheol
SC
Kawakami
Yoshiiku
Y
Shirakawa
Hiroo
H
Takahashi
Shoichi
S
Toyota
Naoyuki
N
Ito
Katsuhide
K
Chayama
Kazuaki
K
D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary / Q000628:therapy*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000556:secondary / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D059408:Pain Management; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome
D001843:Bone Cements