Surgical ablation devices for atrial fibrillation.
The introduction of ablation technology has revolutionized the surgical treatment of atrial fibrillation (AF). It has greatly simplified surgical approaches and has significantly increased the number of procedures being performed. Various energy sources have been used clinically, including cryoablation, radiofrequency, microwave, laser, and high-frequency ultrasound. The goal of these devices is to create conduction block to either block activation wavefronts or to isolate the triggers of AF. All present devices have been shown to have clinical efficacy in some patients. The devices each have their unique advantages and disadvantages. It is important that surgeons develop accurate dose-response curves for new devices in clinically relevant models on both the arrested and beating heart. This will allow the appropriate use of technology to facilitate AF surgery.
Lall
Shelly C
SC
Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, MO, USA.
Damiano
Ralph J
RJ
D055011:Ablation Techniques / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D001281:Atrial Fibrillation / Q000601:surgery*; D004867:Equipment Design; D006329:Heart Conduction System / Q000601:surgery*; D006801:Humans; D010818:Practice Patterns, Physicians' / Q000639:trends*