Rat prefrontal response and prestimulation local field potential power in vivo.
To determine whether spontaneous local field potential (LFP) activities in the rat medial prefrontal cortex influence the responses evoked by hippocampal stimulation, we investigated the relationship between the evoked responses and the LFP powers immediately before the stimulation using anesthetized rats. We demonstrated that the degrees of evoked response showed significant inverse correlations with the prefrontal LFP powers in a specific frequency band (including the gamma band) immediately before the stimulation. The results indicate that the specific frequency band activities in the prefrontal LFPs may be involved in prefrontal responsiveness. Spontaneous LFP activities may have a role in information processing in the hippocampus-prefrontal cortex pathway.
Izaki
Yoshinori
Y
Department of Physiology, St Marianna University School of Medicine, Kawasaki, Japan. yizaki@marianna-u.ac.jp
Fujiwara
Sei-etsu
SE
Akema
Tatsuo
T
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001683:Biological Clocks / Q000502:physiology; D004558:Electric Stimulation; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D006624:Hippocampus / Q000033:anatomy & histology / Q000502:physiology*; D008297:Male; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009474:Neurons / Q000502:physiology; D017397:Prefrontal Cortex / Q000033:anatomy & histology / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D009435:Synaptic Transmission / Q000502:physiology