Treatment and outcome of intestinal failure secondary to enteric neuromuscular disease.
The clinical management of intestinal pseudoobstructive syndromes has, in the broadest of terms, 2 management strategies: optimisation of underlying gastrointestinal motor and absorptive function and, when this is inadequate, adequate nutritional support using enteral and intravenous nutrition to restore and maintain a good nutritional state and growth. With such support, a 10-year survival rate of >80% can be achieved in the most severely affected individuals without recourse to intestinal transplantation.
Hill
Susan
S
Gastroenterology Department, Great Ormond Street Hospital for Children National Health Service Trust, London, UK. hills1@gosh.nhs.uk
D002648:Child; D002664:Child Nutritional Physiological Phenomena / Q000502:physiology*; D002675:Child, Preschool; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000601:surgery / Q000628:therapy*; D009468:Neuromuscular Diseases / Q000601:surgery / Q000628:therapy*; D009751:Nutritional Requirements; D009752:Nutritional Status; D010288:Parenteral Nutrition; D016896:Treatment Outcome