Pulmonary thrombectomy in a patient with hemoglobin Nottingham.
A 36-year-old female with hemoglobin Nottingham (betaFG 5(98) Val --> Gly) causing severe hemolytic anemia and chronic thromboembolic pulmonary hypertension presented with symptomatic subacute right lower lobar pulmonary arterial thrombosis requiring surgical pulmonary thrombectomy. We describe a successful, multidisciplinary approach to the problems associated with this disease, particularly with the use of cardiopulmonary bypass and deep hypothermic circulatory arrest.
Memtsoudis
Stavros G
SG
Department of Anesthesiology, Perioperative and Pain Medicine, Division of Cardiac Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Lekowski
Robert W
RW
Rosenberger
Peter
P
Khalpey
Zain
Z
FitzGerald
Daniel J
DJ
Claypoole
Valorie
V
Courtney
Kevin D
KD
Landzberg
Michael J
MJ
Bunn
H Franklin
HF
Shekar
Prem S
PS
D000328:Adult; D002315:Cardiopulmonary Bypass; D050792:Circulatory Arrest, Deep Hypothermia Induced; D005260:Female; D006453:Hemoglobinopathies / Q000150:complications*; D006455:Hemoglobins, Abnormal; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D011655:Pulmonary Embolism / Q000150:complications / Q000601:surgery*; D017131:Thrombectomy
D006455:Hemoglobins, Abnormal; C075791:hemoglobin Nottingham