title: [A case of primary hepatic epithelioid hemangioendothelioma mimicking metastatic carcinoma].
abstract: Epithelioid hemangioendothelioma is a rare vascular origin tumor which usually occurs in soft tissues, liver, and lung. It usually affects adult women and presents as multiple hepatic nodules with mainly peripheral distribution. It is difficult to diagnose and treat because of non-specific clinical manifestations and findings on the imaging study. Moreover, pathological misdiagnosis is common. We report a case of this rare tumor that was detected incidentally. Final diagnosis was based on histological evidence. A 52-years old man suffered from right upper quadrant abdominal pain for 3 months, and was initially misdiagnosed as a metastatic carcinoma. Physical examination revealed superior cervical lymphadenopathy with mild hepatomegaly. Finally, hepatic epithelioid hemangioendothelioma was diagnosed on the basis of positive immunohistochemical staining for factor VIII, CD34, and VEGF. Our case highlights the importance of a histological diagnosis to avoid misdiagnosis.
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Sang Gi
authors.initials: SG
authors.lastname: Kim
authors.forename: Min Kyu
authors.initials: MK
authors.lastname: Jung
authors.forename: Seong Woo
authors.initials: SW
authors.lastname: Jeon
authors.forename: Chang Min
authors.initials: CM
authors.lastname: Cho
authors.forename: Won Young
authors.initials: WY
authors.lastname: Tak
authors.forename: Young Oh
authors.initials: YO
authors.lastname: Kweon
authors.forename: Sung Kook
authors.initials: SK
authors.lastname: Kim
authors.forename: Yong Hwan
authors.initials: YH
authors.lastname: Choi
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis / Q000276:immunology; D002277:Carcinoma / Q000556:secondary; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography
chemical_list: D018952:Antigens, CD34; D005169:Factor VIII