title: Pericardial hemorrhage due to acetylsalicylic acid in a patient with essential thrombocythemia.
abstract: Essential thrombocythemia is a clonal myeloproliferative disorder that causes thrombocytosis. Essential thrombocythemia is characterized by increased incidence of thrombosis with arterial event more than venous events and hemorrhagic complications. Acetylsalicylic acid enhances both minor and major bleedings. The authors describe pericardial hemorrhage, which is related to the use of low-dose acetylsalicylic acid in a patient with essential thrombocythemia. The patient was successfully managed with clopidogrel therapy during the 16 months follow-up without recurrent thrombotic or hemorrhagic events.
authors.affiliation: Department of Cardiology, Selcuk University Meram Faculty of Medicine, Konya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kayrak
authors.forename: Kadir
authors.initials: K
authors.lastname: Acar
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yazici
authors.forename: Coskun
authors.initials: C
authors.lastname: Kaya
authors.forename: S Selim
authors.initials: SS
authors.lastname: Ayhan
authors.forename: Hasan
authors.initials: H
authors.lastname: Gok
mesh_terms: D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D000077144:Clopidogrel; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000139:chemically induced*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D013920:Thrombocythemia, Essential / Q000188:drug therapy*; D013927:Thrombosis / Q000517:prevention & control; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin