Case reports: minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy.
Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.
Soung
Jennifer
J
Department of Dermatology, Mount Sinai School of Medicine, New York, NY, USA.
Cohen
Justine
J
Phelps
Robert
R
Cohen
Steven R
SR
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D015474:Isotretinoin / Q000627:therapeutic use*; D008297:Male; D008911:Minocycline / Q000009:adverse effects*; D012867:Skin / Q000473:pathology
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D015474:Isotretinoin; D008911:Minocycline