T/NK cell lymphoma presenting as a "blocked nose".
We present the case of a 63-year-old Caucasian male who complained of persistent rhinitis and sinusitis accompanied by a total left-sided nasal blockage. The diagnosis nasal T/NK cell lymphoma was established by histopathological investigation. This case was diagnosed as stage IE lymphoma as no other sites were involved. The patient was treated with CHOP (cyclophosfamide, doxorubicin, vincristin and prednisone) chemotherapy and involved-field radiotherapy. The nasal T/NK cell lymphoma is a rare malignancy, which is known to have an extremely aggressive and destructive course. The mainstay of treatment is locoregional radiotherapy combined with chemotherapy, depending on disease stage. A high index of clinical suspicion is imperative to ensure early diagnosis and ultimately improve disease outcome.
Ketharanathan
Naomi
N
Department of Head and Neck Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, Amsterdam, The Netherlands. n.ketharanathan@gmail.com
van Kipshagen
Peter Jan
PJ
Vasmel
Wies
W
Barbé
Ellis
E
de Vries
Nico
N
D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D054391:Lymphoma, Extranodal NK-T-Cell / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor