Spontaneous final height in Turner's syndrome in Brazil.
Short stature is the main factor of emotional impact in girls and women with Turner's syndrome (TS). Growth hormone, alone or associated with sex steroids, allows better adult height. The results of spontaneous final height (FH) in TS can help to evaluate the real cost-benefit of any treatment to improve FH in patients from the same population. The aim of this study was to determine spontaneous FH in women TS and to look for factors which influence it. We evaluated 58 patients with TS who attained FH. Data of weight and length at birth, parents' heights, karyotype, spontaneous puberty and sex hormone replacement were obtained. Mean FH was 144.8 cm and target height 157.0 cm. FH was correlated only to maternal height. The deficit in FH was lower than that found in other Brazilian studies but similar to that described in the literature. This study may help verify the efficacy of therapeutic actions on FH of Brazilian women with TS.
de Lemos-Marini
Sofia Helena Valente
SH
Paediatric Endocrinology Unit, Department of Paediatrics/CIPED, Faculty of Medical Sciences, State University of Campinas, São Paulo, Brazil. sofia@hc.unicamp.br
Morcillo
André Moreno
AM
Baptista
Maria Tereza Matias
MT
Guerra
Gil
G
Maciel-Guerra
Andréa Trevas
AT
D000293:Adolescent; D000328:Adult; D001827:Body Height / Q000502:physiology*; D001938:Brazil / Q000453:epidemiology; D005220:Fathers; D005260:Female; D006130:Growth Disorders / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009035:Mothers; D011627:Puberty; D012307:Risk Factors; D014424:Turner Syndrome / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology