title: Susceptibility of immature stages of Aedes (Stegomyia) aegypti; vector of dengue and chikungunya to insecticides from India.
abstract: Susceptibility of Aedes aegypti to some insecticides in different geographic areas was conducted during dengue and chikungunya outbreak. At present, the only method of preventing dengue and chikungunya is to control the vector, which is the weakest link in vector-borne diseases. In our study, the susceptibility of A. aegypti collected from urban areas of Delhi, Mumbai, Jodhpur, Chennai and Coimbatore was evaluated against temephos, fenthion, malathion and DDT. The A. aegypti from different locations exhibited 0.33-7.11, 0.36-3.00, 0.65-2.84 and 2.16-20.8 fold more lethal concentration value of 50% (LC50) to temephos, fenthion, malathion and DDT, respectively, compared to susceptible reference strain. The result reveals that A. aegypti from various locations studied are still susceptible to temephos, fenthion and malathion, whereas low level of DDT resistance was noticed in field-collected A. aegypti. Amongst the insecticides tested, temephos was found to be relatively more effective in controlling A. aegypti, followed by fenthion, malathion and DDT.
authors.affiliation: Defence Research and Development Establishment, Defence R&D Organization, Jhansi Road, Gwalior 474002, India. sachinntikar@yahoo.co.in
authors.forename: S N
authors.initials: SN
authors.lastname: Tikar
authors.forename: M J
authors.initials: MJ
authors.lastname: Mendki
authors.forename: K
authors.initials: K
authors.lastname: Chandel
authors.forename: B D
authors.initials: BD
authors.lastname: Parashar
authors.forename: Shri
authors.initials: S
authors.lastname: Prakash
mesh_terms: D000330:Aedes / Q000187:drug effects / Q000254:growth & development / Q000821:virology; D018354:Alphavirus Infections / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D000818:Animals; D002646:Chikungunya virus; D003634:DDT / Q000494:pharmacology; D003715:Dengue / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D003716:Dengue Virus; D005284:Fenthion / Q000494:pharmacology; D007194:India; D007303:Insect Vectors / Q000187:drug effects / Q000254:growth & development / Q000821:virology; D007305:Insecticide Resistance; D007306:Insecticides / Q000494:pharmacology*; D008294:Malathion / Q000494:pharmacology; D021261:Parasitic Sensitivity Tests / Q000379:methods; D000002:Temefos / Q000494:pharmacology; D014504:Urban Health
chemical_list: D007306:Insecticides; D005284:Fenthion; D003634:DDT; D000002:Temefos; D008294:Malathion