Molecular recognition in homogeneous transition metal catalysis: a biomimetic strategy for high selectivity.
Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.
Das
Siddartha
S
Yale Chemistry, New Haven, CT 06520, USA.
Brudvig
Gary W
GW
Crabtree
Robert H
RH
D002384:Catalysis; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D008958:Models, Molecular; D018716:Molecular Mimicry; D028561:Transition Elements / Q000737:chemistry*
D008024:Ligands; D008670:Metals; D028561:Transition Elements