[Clinical application of xenogenic (porcine) acellular dermal atrix (ADM) in scar treatment].
OBJECTIVE
To investigate the role of xenogenic (porcine) ADM as dermal substitute in scar treatment.


METHODS
After scar excision, the wounds were covered with composite grafts of DR procine ADM and autologous thin split-thickness grafts in one stage or in two stages.


RESULTS
22 out of 47 cases were treated in two-staged procedure. After the ADMs were applied to the wound, the autologous thin split-thickness grafts were implanted 7 days later. 25 cases were treated in one-staged procedure. The survival rates of composite grafts were (88.3 +/- 3.7)% for subcutaneous recipient bed and (89.7 +/- 3.4)% for deep fascia recipient bed in group with two-staged procedure, compared with (92.5 +/- 4.1)% and (93.2 +/- 5.2)%, respectively, in group with one-staged procedure. Early after grafts taken, the grafts had a pink colour and smooth surface. The patients were followed up for 90 days at most. The survived composite grafts were durable, elastic, smooth and soft with good function and appearance like normal skin. They could even be pinched up. The scar along the edge of the grafts was slightly hypertrophic.


CONCLUSIONS
The survival rate of composite graft is higher in patients with one-staged procedure. The elasticity and textural of the taken grafts are better on subcutaneous recipient bed than on deep fascia recipient bed, though the function has no difference. Xenogenic (porcine) ADM can be an optimal dermal substitute for wound coverage after scar excision.
Feng
Xiang-sheng
XS
Department of Plastic and Burn Surgery, the First People's Hospital of Foshan, Foshan, China.
Chen
Xiao-dong
XD
Tan
Jia-ju
JJ
Pan
Ying-gen
YG
Wu
Qiu-he
QH
Ruan
Shu-bin
SB
Shen
Rui
R
Zhang
Feng-gang
FG
Lin
Ze-peng
ZP
Wang
Xiao-ping
XP
Zen
Ying-hong
YH
Lin
Yan
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002921:Cicatrix / Q000601:surgery*; D020405:Dermis / Q000166:cytology / Q000637:transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D017768:Skin, Artificial; D013552:Swine; D014183:Transplantation, Heterologous; D055815:Young Adult