title: Genetic analysis of hantaviruses carried by Myodes and Microtus rodents in Buryatia.
abstract: Hantavirus genome sequences were recovered from tissue samples of Myodes rufocanus, Microtus fortis and Microtus oeconomus captured in the Baikal area of Buryatia, Russian Federation. Genetic analysis of S- and M-segment sequences of Buryatian hantavirus strains showed that Myodes-associated strains belong to Hokkaido virus (HOKV) type while Microtus-associated strains belong to Vladivostok virus (VLAV) type. On phylogenetic trees Buryatian HOKV strains were clustered together with M. rufocanus- originated strains from Japan, China and Far-East Russia (Primorsky region). Buryatian Microtus- originated strains shared a common recent ancestor with M. fortis- originated VLAV strain from Far-East Russia (Vladivostok area). Our data (i) confirm that M. rufocanus carries a hantavirus which is similar to but distinct from both Puumala virus carried by M. glareolus and Muju virus associated with M. regulus, (ii) confirm that M. fortis is the natural host for VLAV, and (iii) suggest M. oeconomus as an alternative host for VLAV.
authors.affiliation: Department of Virology, Haartman Institute, University of Helsinki, Finland. anguelina.pljusnina@helsinki.fi
authors.forename: Angelina
authors.initials: A
authors.lastname: Plyusnina
authors.forename: Juha
authors.initials: J
authors.lastname: Laakkonen
authors.forename: Jukka
authors.initials: J
authors.lastname: Niemimaa
authors.forename: Kirill
authors.initials: K
authors.lastname: Nemirov
authors.forename: Galina
authors.initials: G
authors.lastname: Muruyeva
authors.forename: Boshikto
authors.initials: B
authors.lastname: Pohodiev
authors.forename: Ake
authors.initials: A
authors.lastname: Lundkvist
authors.forename: Antti
authors.initials: A
authors.lastname: Vaheri
authors.forename: Heikki
authors.initials: H
authors.lastname: Henttonen
authors.forename: Olli
authors.initials: O
authors.lastname: Vapalahti
authors.forename: Alexander
authors.initials: A
authors.lastname: Plyusnin
mesh_terms: D000818:Animals; D016679:Genome, Viral; D006476:Orthohantavirus / Q000145:classification / Q000235:genetics*; D018778:Hantavirus Infections / Q000662:veterinary* / Q000821:virology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012376:Rodent Diseases / Q000821:virology*; D012377:Rodentia / Q000145:classification / Q000821:virology*; D012800:Siberia; D013045:Species Specificity