title: Formation of 4-vinyl guaiacol as an intermediate in bioconversion of ferulic acid by Schizophyllum commune.
abstract: In order to utilize phenolic compounds in unused biomass resources, the metabolic pathway of ferulic acid by way of a white-rot fungus, Schizophyllum commune, was investigated. Ferulic acid was immediately degraded, and the formation of 4-vinyl guaiacol was confirmed by GC-MS analysis. The metabolic test of ferulic acid and its degradation products indicated that S. commune converted ferulic acid into 4-vinyl guaiacol by decarboxylation. This was then oxidized to vanillin and vanillic acid. This result indicates that S. commune distinguished ferulic acid from lignins and metabolized it specifically.
authors.affiliation: Biological Function Science Course, Graduate School of Agriculture, Kyoto Prefectural University, Kyoto, Japan. oguram@scc.u-tokai.ac.jp
authors.forename: Sho-ichi
authors.initials: S
authors.lastname: Tsujiyama
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Ueno
mesh_terms: D001547:Benzaldehydes / Q000378:metabolism; D018533:Biomass; D003373:Coumaric Acids / Q000737:chemistry / Q000378:metabolism*; D006139:Guaiacol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D008958:Models, Molecular; D012567:Schizophyllum / Q000378:metabolism*; D014641:Vanillic Acid / Q000737:chemistry / Q000378:metabolism
chemical_list: D001547:Benzaldehydes; D003373:Coumaric Acids; D006139:Guaiacol; C014245:4-vinylguaiacol; C004999:ferulic acid; C100058:vanillin; D014641:Vanillic Acid