title: Around-the-clock, rapid diagnosis of influenza by means of membrane chromatography antigen testing confirmed by polymerase chain reaction.
abstract: One rapid membrane chromatography test and 2 immunofluorescence tests were compared with polymerase chain reaction as tools for the diagnosis of influenza in 277 patients treated in an emergency department. The sensitivity on days 1-3 of symptoms was 71% for the rapid membrane chromatography test, 70% for the first immunofluorescence test, and 79% for the second immunofluorescence test. Rapid tests are useful for round-the-clock identification of influenza, with follow-up polymerase chain reaction used for confirmation.
authors.affiliation: Department of Clinical Sciences, Malmö Infectious Disease Research Unit, Malmö University Hospital, Lund University, Malmö, Sweden.
authors.forename: Anna C
authors.initials: AC
authors.lastname: Nilsson
authors.forename: Birgitta
authors.initials: B
authors.lastname: Alemo
authors.forename: Per
authors.initials: P
authors.lastname: Björkman
authors.forename: Lena
authors.initials: L
authors.lastname: Dillner
authors.forename: Asa
authors.initials: A
authors.lastname: Melhus
authors.forename: Berit
authors.initials: B
authors.lastname: Nilsson
authors.forename: Anders
authors.initials: A
authors.lastname: Widell
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000956:Antigens, Viral / Q000032:analysis*; D002845:Chromatography / Q000295:instrumentation*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques / Q000295:instrumentation / Q000379:methods*; D007251:Influenza, Human / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000821:virology; D009975:Orthomyxoviridae / Q000302:isolation & purification*; D010614:Pharynx / Q000821:virology; D016133:Polymerase Chain Reaction / Q000379:methods*
chemical_list: D000956:Antigens, Viral