Bisphosphonate-related osteonecrosis of the jaws (ONJ): a report of two cases.
Osteonecrosis of thejaw (ONJ) is strongly associated with the use of aminobisphosphonates. Herein, the authors report two cases of ONJ after intravenous bisphosphonate therapy including clinical presentations, X-ray, and pathological findings. Since there is no definite treatment for ONJ, the focus should be on prevention with a dental evaluation for all patients before starting bisphosphonates.
Pongchaiyakul
Chatlert
C
Department of Medicine, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. pchatl@kku.ac.th
Auraiwan
Krittinant
K
Kotruchin
Praew
P
Kularbkaew
Churairat
C
D000328:Adult; D004164:Diphosphonates / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007568:Jaw / Q000187:drug effects / Q000473:pathology*; D008297:Male; D008334:Mandible / Q000187:drug effects / Q000473:pathology*; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced*
D004164:Diphosphonates