title: Bronchus-associated lymphoid tissue lymphomas: an update of a rare extranodal maltoma.
abstract: Mucosa-associated lymphoid tissue (MALT) lymphomas were first described by Isaacson and Wright in 1983 in a small series of patients with low-grade B-cell gastrointestinal lymphomas. Although MALT lymphomas occur most frequently in the stomach, they have also been described in various non-gastrointestinal sites, such as the salivary gland, conjunctiva, thyroid, orbit, lung, breast, kidney, skin, liver, uterus, and prostate. The risk of a diagnostic dilemma is reduced by the favorable prognosis of this low-grade lymphoma and its tendency to remain localized to the primary site for a long time. On therapeutic grounds, in contrast to nodal lymphomas, low-grade MALT lymphomas also respond favorably to local treatments, such as surgery and/or local radiation therapy. The outcome and prognosis of low-grade MALT lymphomas are more favorable than those for other extranodal lymphomas. The purpose of this review is to point out the state of the art regarding bronchus-associated lymphoid tissues lymphomas in terms of etiology, pathogenesis, clinics, and therapeutics, including our single-center experience of 23 cases.
authors.affiliation: Institute of Hematology and Medical Oncology, L. & A. Seràgnoli, University of Bologna, Italy. plzinzo@med.unibo.it
authors.forename: Pier Luigi
authors.initials: PL
authors.lastname: Zinzani
authors.forename: Venerino
authors.initials: V
authors.lastname: Poletti
authors.forename: Maurizio
authors.initials: M
authors.lastname: Zompatori
authors.forename: Monica
authors.initials: M
authors.lastname: Tani
authors.forename: Lucia
authors.initials: L
authors.lastname: Spaggiari
authors.forename: Sara
authors.initials: S
authors.lastname: Tomassetti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Broccoli
authors.forename: Enrico
authors.initials: E
authors.lastname: Derenzini
authors.forename: Michele
authors.initials: M
authors.lastname: Baccarani
mesh_terms: D001980:Bronchi / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D008198:Lymph Nodes / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D009928:Organ Specificity; D017741:Survivors