title: An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systems.
abstract: A novel design of solid dynamic phantom with tissue-like optical properties is presented, which contains variable regions of contrast which are activated electrically. Reversible changes in absorption are produced by localized heating of targets impregnated with thermochromic pigment. A portable, battery-operated prototype has been constructed, and its optical and temporal characteristics have been investigated. The phantom has been developed as a means of assessing the performance of diffuse optical imaging systems, such as those used to monitor haemodynamic changes in the brain and other tissues. Images of the phantom have been reconstructed using data acquired with a continuous wave optical topography system.
authors.affiliation: Department of Medical Physics & Bioengineering, University College London, Gower Street, London WC1E 6BT, UK.
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Hebden
authors.forename: Joanna
authors.initials: J
authors.lastname: Brunker
authors.forename: Teresa
authors.initials: T
authors.lastname: Correia
authors.forename: Ben D
authors.initials: BD
authors.lastname: Price
authors.forename: Adam P
authors.initials: AP
authors.lastname: Gibson
authors.forename: N L
authors.initials: NL
authors.lastname: Everdell
mesh_terms: D004574:Electromagnetic Fields; D004867:Equipment Design; D019544:Equipment Failure Analysis; D019047:Phantoms, Imaging; D041622:Tomography, Optical / Q000295:instrumentation* / Q000379:methods; D051598:Whole Body Imaging / Q000295:instrumentation* / Q000379:methods