Neighborhood deprivation, individual socioeconomic status, and cognitive function in older people: analyses from the English Longitudinal Study of Ageing.
OBJECTIVE
To assess the relationship between cognitive function, socioeconomic status, and neighborhood deprivation (lack of local resources of all types, financial and otherwise).


METHODS
Nationally representative cross-section.


METHODS
The English Longitudinal Study of Ageing (ELSA).


METHODS
Seven thousand one hundred twenty-six community-dwelling individuals aged 52 and older and resident in urban areas.


METHODS
Individual cognitive function score and index of multiple deprivation (IMD) at the Super Output Area level, adjusting for health, lifestyle, and sociodemographic confounders. Analyses were conducted separately according to sex and age group (52-69 and > or = 70).


RESULTS
IMD affected cognitive function independent of the effects of education and socioeconomic status. For example, in fully adjusted models, women aged 70 and older had a standardized cognitive function score (z-score) that was 0.20 points (95% confidence interval (CI)=0.01-0.39) lower in the bottom 20% of wealth than the top 20%, 0.44 points (95% CI=0.20-0.69) lower in the least-educated group than in the most educated, and 0.31 points (95% CI 0.15-0.48) lower if resident lived in an area in the bottom 20% of IMD than in the top 20%.


CONCLUSIONS
In community-based older people in urban neighborhoods, neighborhood deprivation--living in a neighborhood with high levels of deprivation, compared with national levels--is associated with cognitive function independent of individual socioeconomic circumstances. The mechanisms underlying this relationship are unclear and warrant further investigation.
Lang
Iain A
IA
Epidemiology and Public Health Group, Peninsula Medical School, Exeter, United Kingdom. iain.lang@pms.ac.uk
Llewellyn
David J
DJ
Langa
Kenneth M
KM
Wallace
Robert B
RB
Huppert
Felicia A
FA
Melzer
David
D
D000368:Aged; D003072:Cognition Disorders / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D016018:Least-Squares Analysis; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011204:Poverty Areas; D012307:Risk Factors; D012923:Social Class; D006113:United Kingdom / Q000453:epidemiology; D014505:Urban Population