title: Pulmonary thrombectomy in a patient with hemoglobin Nottingham.
abstract: A 36-year-old female with hemoglobin Nottingham (betaFG 5(98) Val --> Gly) causing severe hemolytic anemia and chronic thromboembolic pulmonary hypertension presented with symptomatic subacute right lower lobar pulmonary arterial thrombosis requiring surgical pulmonary thrombectomy. We describe a successful, multidisciplinary approach to the problems associated with this disease, particularly with the use of cardiopulmonary bypass and deep hypothermic circulatory arrest.
authors.affiliation: Department of Anesthesiology, Perioperative and Pain Medicine, Division of Cardiac Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Stavros G
authors.initials: SG
authors.lastname: Memtsoudis
authors.forename: Robert W
authors.initials: RW
authors.lastname: Lekowski
authors.forename: Peter
authors.initials: P
authors.lastname: Rosenberger
authors.forename: Zain
authors.initials: Z
authors.lastname: Khalpey
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: FitzGerald
authors.forename: Valorie
authors.initials: V
authors.lastname: Claypoole
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Courtney
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Landzberg
authors.forename: H Franklin
authors.initials: HF
authors.lastname: Bunn
authors.forename: Prem S
authors.initials: PS
authors.lastname: Shekar
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass; D050792:Circulatory Arrest, Deep Hypothermia Induced; D005260:Female; D006453:Hemoglobinopathies / Q000150:complications*; D006455:Hemoglobins, Abnormal; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D011655:Pulmonary Embolism / Q000150:complications / Q000601:surgery*; D017131:Thrombectomy
chemical_list: D006455:Hemoglobins, Abnormal; C075791:hemoglobin Nottingham