Present techniques for antibody removal.
Renal transplantation into a patient with a positive cytotoxic cross-match or with an incompatible blood group inevitably results in acute humoral rejection, unless the HLA or anti-A/B antibodies have been removed before transplantation. Although there are several procedures to remove HLA and anti-A/B antibodies, plasmapheresis and immunoadsorption are the most commonly used. In this report, presently available techniques for antibody removal are briefly reviewed.
Tydén
Gunnar
G
Department of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden. gunnar.tyden@karolinska.se
Kumlien
Gunilla
G
Efvergren
Mats
M
D000017:ABO Blood-Group System; D000327:Adsorption; D000906:Antibodies / Q000737:chemistry; D001787:Blood Group Incompatibility; D006085:Graft Survival; D006801:Humans; D007074:Immunoglobulin G / Q000737:chemistry; D007075:Immunoglobulin M / Q000737:chemistry; D007164:Immunosorbents / Q000737:chemistry; D016030:Kidney Transplantation / Q000379:methods*; D008970:Molecular Weight; D010951:Plasma Exchange / Q000379:methods; D010956:Plasmapheresis / Q000379:methods
D000017:ABO Blood-Group System; D000906:Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007164:Immunosorbents