title: Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma.
abstract: We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.
authors.affiliation: Laboratory of Immunoregulation and Microbiology, Centro de Pesquisa Conçalo Moniz-Fundação Oswaldo Cruz, Bahia, Brazil. lourdesfarre@hotmail.com
authors.forename: Lourdes
authors.initials: L
authors.lastname: Farre
authors.forename: Maria de Fátima Paim
authors.initials: Mde F
authors.lastname: de Oliveira
authors.forename: Janeusa
authors.initials: J
authors.lastname: Primo
authors.forename: Anne-Mieke
authors.initials: AM
authors.lastname: Vandamme
authors.forename: Johan
authors.initials: J
authors.lastname: Van Weyenbergh
authors.forename: Achiléa L
authors.initials: AL
authors.lastname: Bittencourt
mesh_terms: D002648:Child; D003872:Dermatitis / Q000134:cerebrospinal fluid / Q000821:virology*; D005260:Female; D015481:HTLV-I Antibodies / Q000134:cerebrospinal fluid; D015368:Human T-lymphotropic virus 1 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000134:cerebrospinal fluid / Q000821:virology*; D015493:Paraparesis, Tropical Spastic / Q000134:cerebrospinal fluid / Q000821:virology*; D016133:Polymerase Chain Reaction
chemical_list: D015481:HTLV-I Antibodies