Human herpesvirus-6 DNAemia in immunosuppressed adult patients with leukemia at risk for mold infection.
Little is known about human herpesvirus-6 (HHV-6) in leukemia patients. We prospectively followed 37 leukemia patients at risk for mold infection. HHV-6 DNA was detected from whole blood specimens in 11 patients (30%). History of granulocyte transfusions (p=0.05) and prior relapse of leukemia (p=0.07) were the only independent predictors of HHV-6 DNAemia.
Chemaly
Roy F
RF
Torres
Harrys A
HA
Hachem
Ray
R
Kontoyiannis
Dimitrios P
DP
Safdar
Amar
A
Raad
Issam I
II
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000821:virology*; D001230:Aspergillus / Q000378:metabolism; D001803:Blood Transfusion; D004279:DNA, Viral / Q000097:blood*; D006098:Granulocytes / Q000378:metabolism; D015654:Herpesvirus 6, Human / Q000235:genetics*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007938:Leukemia / Q000097:blood* / Q000276:immunology / Q000821:virology*; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D013997:Time Factors
D004279:DNA, Viral; D007166:Immunosuppressive Agents