title: Treatment of eczema.
abstract: Eczema is a chronic inflammatory skin disease that has reached nearly epidemic proportions in childhood. Moreover, it is a difficult disease to control and, with its onset in childhood, is often the first manifestation of atopy. The clinical features of eczema include itchy red skin accompanied by dryness and lichenification. In the past, treatment options consisted primarily of avoidance of soap and water. These options have considerably improved with both nonpharmacologic and pharmacologic approaches. However, eczema is still a treatment challenge. Part of the problem in developing new treatment options has been the relative failure in translating basic science information into clinical application. It is hoped that the newer biologics will help bridge this gap and lead to greater success rates.
authors.affiliation: Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, 451 E. Health Sciences Drive, Suite 6510, Davis, CA 95616, USA. cc2chang@sbcglobal.net
authors.forename: Christopher
authors.initials: C
authors.lastname: Chang
authors.forename: Carl L
authors.initials: CL
authors.lastname: Keen
authors.forename: M Eric
authors.initials: ME
authors.lastname: Gershwin
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens; D001942:Breast Feeding; D002648:Child; D002675:Child, Preschool; D000529:Complementary Therapies / Q000639:trends; D003937:Diagnosis, Differential; D004485:Eczema / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications; D005544:Forecasting; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use*; D007167:Immunotherapy; D007223:Infant; D008875:Middle Aged; D010789:Phototherapy; D008517:Phytotherapy; D012307:Risk Factors; D012915:Soaps / Q000627:therapeutic use*
chemical_list: D000305:Adrenal Cortex Hormones; D000485:Allergens; D006634:Histamine H1 Antagonists; D007155:Immunologic Factors; D012915:Soaps