title: Treatment of postdermabrasion facial hypertrophic and keloid scars with intralesional 5-Fluorouracil injections.
abstract: Hypertrophic and keloid scarring is a known complication of dermabrasion facial resurfacing, although only a very small fraction of patients experience it. Treatment with intralesional corticosteroid injections and flashed pumped vascular dye laser is recommended in the literature. The treatment of keloid and hypertrophic scars using intralesional 5-fluorouracil (5-FU) injections has been well described, but there is no literature regarding use of the same treatment for postdermabrasion hypertrophic and keloid scars. In this case report, we describe a 67-year-old woman with persistent postdermabrasion facial hypertrophic and keloid scars that were treated at our scar clinic using intralesional 5-FU injections.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Sheba Medical Center, Tel-hashomer (affiliated with Sackler School of Medicine, Tel-Aviv University, Israel), Ramat Gan 52620, Israel. orengoldan@gmail.com
authors.forename: O
authors.initials: O
authors.lastname: Goldan
authors.forename: O
authors.initials: O
authors.lastname: Weissman
authors.forename: E
authors.initials: E
authors.lastname: Regev
authors.forename: J
authors.initials: J
authors.lastname: Haik
authors.forename: E
authors.initials: E
authors.lastname: Winkler
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D017439:Cicatrix, Hypertrophic / Q000188:drug therapy*; D005145:Face; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015552:Injections, Intralesional; D007627:Keloid / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil