Pancytopenia with bleeding tendency associated with bone marrow aplasia in a Holstein calf.
An 11-day-old Holstein calf presented with a high rectal temperature and tachypnea. Treatment with antibiotics and non-steroidal anti-inflammatory drugs did not improve the clinical signs. Bleeding tendency, with several hemorrhage spots on the body surface, appeared five days after admission. Severe pancytopenia was observed in the blood examination. The calf died on the 11th day after admission with severe bleeding from an injection site. Necropsy findings revealed that the pancytopenia had resulted from severe bone marrow aplasia. A congenital disorder was suspected to be the cause of pancytopenia associated with bone marrow aplasia.
Shimada
Asuka
A
Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
Onozato
Tomoya
T
Hoshi
Eriko
E
Togashi
Yoshihiko
Y
Matsui
Motozumi
M
Miyake
Yoh-Ichi
Y
Kobayashi
Yoshiyasu
Y
Furuoka
Hidefumi
H
Matsui
Takane
T
Sasaki
Naoki
N
Ishii
Mitsuo
M
Inokuma
Hisashi
H
D000741:Anemia, Aplastic / Q000150:complications / Q000662:veterinary*; D000818:Animals; D001855:Bone Marrow Diseases / Q000150:complications / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis*; D006470:Hemorrhage / Q000150:complications / Q000662:veterinary*; D010198:Pancytopenia / Q000150:complications / Q000662:veterinary*