Persistence of vaccinia at the site of smallpox vaccination.
Persistence of vaccinia at vaccination sites may help determine the risk associated with secondary transmission. Culture, PCR, and antigen detection were performed on serial vaccination site swab specimens. On day 21 after vaccination, 37% of volunteers were culture positive, most of whom had received vaccine for the first time. Vaccinia is detectable at least through day 21 after vaccination.
Cummings
James F
JF
Infectious Diseases Service, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
Polhemus
Mark E
ME
Hawkes
Clifton
C
Klote
Mary
M
Ludwig
George V
GV
Wortmann
Glenn
G
D006801:Humans; D011446:Prospective Studies; D012899:Smallpox / Q000517:prevention & control* / Q000821:virology; D012900:Smallpox Vaccine / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D014616:Vaccinia virus / Q000276:immunology / Q000302:isolation & purification* / Q000378:metabolism
D012900:Smallpox Vaccine