title: Pancytopenia with bleeding tendency associated with bone marrow aplasia in a Holstein calf.
abstract: An 11-day-old Holstein calf presented with a high rectal temperature and tachypnea. Treatment with antibiotics and non-steroidal anti-inflammatory drugs did not improve the clinical signs. Bleeding tendency, with several hemorrhage spots on the body surface, appeared five days after admission. Severe pancytopenia was observed in the blood examination. The calf died on the 11th day after admission with severe bleeding from an injection site. Necropsy findings revealed that the pancytopenia had resulted from severe bone marrow aplasia. A congenital disorder was suspected to be the cause of pancytopenia associated with bone marrow aplasia.
authors.affiliation: Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
authors.forename: Asuka
authors.initials: A
authors.lastname: Shimada
authors.forename: Tomoya
authors.initials: T
authors.lastname: Onozato
authors.forename: Eriko
authors.initials: E
authors.lastname: Hoshi
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Togashi
authors.forename: Motozumi
authors.initials: M
authors.lastname: Matsui
authors.forename: Yoh-Ichi
authors.initials: Y
authors.lastname: Miyake
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Furuoka
authors.forename: Takane
authors.initials: T
authors.lastname: Matsui
authors.forename: Naoki
authors.initials: N
authors.lastname: Sasaki
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Ishii
authors.forename: Hisashi
authors.initials: H
authors.lastname: Inokuma
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications / Q000662:veterinary*; D000818:Animals; D001855:Bone Marrow Diseases / Q000150:complications / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis*; D006470:Hemorrhage / Q000150:complications / Q000662:veterinary*; D010198:Pancytopenia / Q000150:complications / Q000662:veterinary*