Evidence supporting nutritional interventions for persons in early stage Alzheimer's disease (AD).
The purpose of this paper is to grade research evidence supporting nutritional interventions for persons with early stage dementias and to report the recommendations of a consensus panel. Thirty four studies were reviewed in the areas of dietary restriction, antioxidants, and Mediterranean diet with strong support from epidemiological studies found in all three areas. The body of evidence to support nutritional interventions in the prevention and treatment of AD is growing and has potential as a treatment modality following translational studies.
Burgener
S C
SC
University North Carolina at Greensboro, Recreation, Tourism and Hospitality, HHP Building, Greensboro, NC, USA.
Buettner
L
L
Coen Buckwalter
K
K
Beattie
E
E
Bossen
A L
AL
Fick
D M
DM
Fitzsimmons
S
S
Kolanowski
A
A
Richeson
N E
NE
Rose
K
K
Schreiner
A
A
Pringle Specht
J K
JK
Testad
I
I
Yu
F
F
McKenzie
S
S
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications / Q000628:therapy*; D032921:Consensus; D004032:Diet; D018450:Disease Progression; D019317:Evidence-Based Medicine; D006801:Humans; D044342:Malnutrition / Q000209:etiology / Q000517:prevention & control*; D044623:Nutrition Therapy; D018570:Risk Assessment; D012307:Risk Factors