Distribution of slow muscle fiber of muscle spindle in postnatal rat masseter muscle.
We investigated the properties of the muscle spindle in the masseter muscle at an immunohistochemical level in rats fed for 6 weeks. Slow myosin heavy chain (MyHC) isoforms were measured and intrafusal fibers in the muscle spindle were studied to determine the relationship between the superficial and deep regions of rat masseter muscle after alternated feeding pattern. However, muscle spindles were found in both regions, mainly in the deep region of the posterior superficial region of masseter muscle. The total number of the slow fiber in the intrafusal fiber and number of muscle spindle in the deep region were high from 5 to 8 weeks old in spite of various dimensions of data such as diameter and the compositions of the intrafusal fiber. The relationship of the protein expression of slow MyHC in the two regions at 5 weeks old reversed five weeks later (10 weeks old). This period is an important stage because the mastication system in masseter muscle with muscle spindle may be changed during the alternated feeding pattern of suckling to mastication. The changes may be a marker of the feeding system and of the control by the tension receptor of muscle spindle in this stage of masseter muscle after postnatal development.
Sato
Iwao
I
Department of Anatomy, School of Life Dentistry at Tokyo, the Nippon Dental University, 1-9-20 Fujimi Chiyoda-Ku, Tokyo, 102-8159 Japan. iwaoa1@tokyo.ndu.ac.jp
Imura
Kosuke
K
Miwa
Yoko
Y
Ide
Yoshiaki
Y
Murata
Megumi
M
Sunohara
Masataka
M
D000375:Aging / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D002452:Cell Count; D002454:Cell Differentiation / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D007150:Immunohistochemistry; D008297:Male; D008406:Masseter Muscle / Q000254:growth & development* / Q000294:innervation*; D008409:Mastication / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology; D018657:Muscle Fibers, Slow-Twitch / Q000166:cytology / Q000378:metabolism*; D009470:Muscle Spindles / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D018995:Myosin Heavy Chains / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013391:Sucking Behavior / Q000502:physiology
D018995:Myosin Heavy Chains