title: [A patient who sufferred pulmonary tuberculosis with syndrome of inappropriate secretion of antidiuretic hormone, after radiotherapy for pulmonary adenocarcinoma].
abstract: A 62-year-old man presented in June 2006 with right thoracic pain, cough, and weight loss, which had persisted for 3 months. Chest X-ray showed a mass-like shadow in the right pulmonary apex, suggesting a stage IIIb adenocarcinoma which was confirmed by biopsy. We gave a total radiation dose of 60 Gy, after this which general malaise and weakness were noted. The results of endocrinological examinations suggested syndrome of inappropriate antidiuretic hormone secretion (SIADH). Thoracic CT showed ground-glass opacity (GGO) in both lungs, and we could not rule out pulmonary tuberculosis. A sputum was positive for acid-fast stain and PCR-Tb, suggesting that SIADH was associated with pulmonary tuberculosis. Water restriction, i.v. physiological saline, and antituberculosis therapy relieved hyponatremia and the symptoms.
authors.affiliation: Department of Respiratory Medicine, Fujita Health University Second Educational Hospital.
authors.forename: Kashin
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Takahiko
authors.initials: T
authors.lastname: Horiguchi
authors.forename: Hideharu
authors.initials: H
authors.lastname: Hata
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hirose
authors.forename: Mamoru
authors.initials: M
authors.lastname: Shiga
authors.forename: Rieko
authors.initials: R
authors.lastname: Kondo
authors.forename: Souichi
authors.initials: S
authors.lastname: Tachikawa
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology*; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D014397:Tuberculosis, Pulmonary / Q000150:complications*