Cathepsin E: a mini review.
Cathepsin E is a major intracellular aspartic protease which is predominantly present in the cells of immune system and is frequently implicated in antigen processing via the MHC class II pathway. In the present review some of the known features of cathepsin E such as tissue distribution, subcellular localization, enzymatic properties, intracellular trafficking, gene regulation and associated physiological conditions are highlighted.
Zaidi
Nousheen
N
Medical and Natural Sciences Research Centre, University of Tübingen, Ob dem Himmelreich 7, 72074 Tuebingen, Germany.
Kalbacher
Hubert
H
D000818:Animals; D017951:Antigen Presentation / Q000502:physiology; D020059:Cathepsin E / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D004790:Enzyme Induction / Q000502:physiology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D009928:Organ Specificity / Q000502:physiology; D011499:Protein Processing, Post-Translational; D013379:Substrate Specificity / Q000502:physiology
D004791:Enzyme Inhibitors; D020059:Cathepsin E