title: Unprecedented negishi coupling at C-br in the presence of a stannyl group as a convenient approach to pyridinylstannanes and their application in liquid crystal synthesis.
abstract: The 2-bromo-5(or 6)-tri-n-butylstannylpyridines, prepared from dibromopyridines and i-PrMgCl at room temperature, undergo Negishi coupling with either alkyl or arylzinc chlorides. The new alkyl- and aryl-substituted pyridylstannanes produced are shown to be suitable for further functionalization by Stille coupling. A group of new liquid crystalline materials with aromatic cores comprised of pyridine and thiophene rings were prepared utilizing these new pyridinylstannanes as key intermediates.
authors.affiliation: Chemistry Department, Kent State University, Kent, Ohio 44242-0001, USA.
authors.forename: Yulia A
authors.initials: YA
authors.lastname: Getmanenko
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Twieg