Bone apposition around two different sandblasted and acid-etched titanium implant surfaces: a histomorphometric study in canine mandibles.
OBJECTIVE
The aim of this study was to evaluate bone apposition to a modified sandblasted and acid-etched (SLA) implant surface (modSLA) in the canine mandible as compared with the standard SLA surface.


METHODS
In this experimental study, all mandibular premolars and first molars were extracted bilaterally in five foxhounds. After a healing period of 6 months, each side of the mandible received six randomly assigned dental implants alternating between the standard SLA and modSLA surface. The dogs were sacrificed at 2 weeks (n=2) or 4 weeks (n=3) after implant placement. Histologic and histomorphometric analyses were then performed for each implant.


RESULTS
The microscopic healing patterns at weeks 2 and 4 for the two implant types with the standard SLA and modSLA surfaces showed similar qualitative findings. New bone tissue had already established direct contact with implant surfaces after 2 weeks of healing. The mean percentage of newly formed bone in contact with the implant (BIC) was significantly greater for modSLA (28.2+/-7.9%) than for SLA (22.2+/-7.3%) (P<0.05). This difference was no longer evident after 4 weeks. An increase in BIC for both implant surface types occurred from weeks 2 to 4. This increase was statistically significant when compared with SLA at 2 weeks (P<0.05), but not when compared with modSLA at 2 weeks.


CONCLUSIONS
The data from the present study demonstrate significantly more bone apposition for the modSLA surface than the standard SLA surface after 2 weeks of healing. This increased bone apposition may allow a further reduction of the healing period following implant placement for patients undergoing early loading procedures.
Bornstein
Michael M
MM
Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Valderrama
Pilar
P
Jones
Archie A
AA
Wilson
Thomas G
TG
Seibl
Reinhart
R
Cochran
David L
DL
D000818:Animals; D001857:Bone Matrix / Q000098:blood supply*; D045662:Dental Etching / Q000379:methods; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D004285:Dogs; D020007:Implants, Experimental; D008297:Male; D008334:Mandible / Q000601:surgery; D009584:Nitrogen / Q000494:pharmacology; D016348:Osseointegration; D011897:Random Allocation; D012965:Sodium Chloride; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry; D017155:Wettability / Q000187:drug effects
D015921:Dental Implants; D012965:Sodium Chloride; D014025:Titanium; D009584:Nitrogen