Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model.
Xue
Feng
F
Organ Transplantation Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Zhang
Jian-jun
JJ
Qiu
Feng
F
Zhang
Ming
M
Chen
Xiao-song
XS
Li
Qi-gen
QG
Han
Long-zhi
LZ
Xi
Zhi-feng
ZF
Xia
Qiang
Q
D000199:Actins / Q000737:chemistry; D000577:Amides / Q000627:therapeutic use*; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D003599:Cytoskeleton / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005260:Female; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D011725:Pyridines / Q000627:therapeutic use*; D018631:ras Proteins / Q000032:analysis; D054460:rho-Associated Kinases / Q000032:analysis / Q000037:antagonists & inhibitors*; D020742:rhoA GTP-Binding Protein / Q000032:analysis; D000075024:rhoC GTP-Binding Protein
D000199:Actins; D000577:Amides; D004791:Enzyme Inhibitors; D011725:Pyridines; C108830:Y 27632; D054460:rho-Associated Kinases; C512911:Rhoc protein, mouse; D018631:ras Proteins; D020742:rhoA GTP-Binding Protein; D000075024:rhoC GTP-Binding Protein