[A case of sclerosing cholangitis showing response to prednisolone].
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive fibrosis and destruction of intra- and extrahepatic bile ducts resulting in hepatic failure and death. Only the liver transplantation is the possible treatment for patients to survive. There has been a few reports that steroid is an effective treatment in autoimmune variant sclerosing cholangitis, which is thought to be a familial diseases with different etiology, and steroid responsive biliary strictures be named as immunoglobulin G4 (IgG4)-associated cholangitis (IAC). There is no reliable data regarding effective steroid treatment in autoimmune variant sclerosing cholangitis in Korea. We report a case of 32-year-old male with sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and liver biopsy, showing favorable response to prednisolone therapy.
Shin
Yo Sig
YS
Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea.
Jang
Yong Seok
YS
Kang
Min Kyoung
MK
Jang
Byoung Kuk
BK
Park
Kyung Sik
KS
Hwang
Jae Seok
JS
Kwon
Jung Hyeok
JH
Kang
Yu Na
YN
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D011239:Prednisolone