title: [Reduced incidence of Staphylococcus isolation in nosocomial setting after introducing preoperative antibiotic prophylaxis guidelines].
abstract: We compare epidemiological data from two twelve-month periods, before and after the introduction of preoperative antibiotic prophylaxis guidelines at Carlo Poma hospital in Mantova, Italy, in June 2003. Considering the results from the microbiology laboratory and the data from the pharmacy, concerning the consumption of some antimicrobials, we noted a significant decrease in the incidence of methicillin-resistant Staphylococcus aureus (MRSA) in surgical wards, where the incidence of MRSA had previously exceeded that in medical wards. At the same time, analysis of antibiotic consumption revealed a considerable decrease in third and fourth-generation cephalosporins and an increasing use of cephazolin, in compliance with prophylaxis protocol rules. This trend was confirmed by analysis of the same data regarding the first six months of 2006.
authors.affiliation: Unità Operativa Malattie Infettive, Azienda Ospedaliera Carlo Poma Mantova, Italy.
authors.forename: Gianni
authors.initials: G
authors.lastname: Gattuso
authors.forename: Davide
authors.initials: D
authors.lastname: Berra
authors.forename: Loredana
authors.initials: L
authors.lastname: Palvarini
authors.forename: Donatella
authors.initials: D
authors.lastname: Tomasoni
authors.forename: Cristina
authors.initials: C
authors.lastname: Chiarelli
authors.forename: Raffaello
authors.initials: R
authors.lastname: Stradoni
authors.forename: Alfredo
authors.initials: A
authors.lastname: Scalzini
mesh_terms: D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data; D002511:Cephalosporins / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use*; D003428:Cross Infection / Q000453:epidemiology* / Q000517:prevention & control; D004363:Drug Utilization / Q000706:statistics & numerical data; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D016106:Methicillin Resistance; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D011229:Preanesthetic Medication / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000517:prevention & control; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data
chemical_list: D002511:Cephalosporins