Neurological presentation of Wilson's disease in a patient after liver transplantation.
We report of a 32-year-old man who showed dystonic symptoms within few days after liver transplantation (LT). The clinical, biochemical, and, finally, genetic evaluation confirmed Wilson's disease diagnosis in this patient. We suspect that extrapyramidal signs in this case could be a result of acute brain injury because of the massive copper release from liver to the circulation just before and during LT.
Litwin
Tomasz
T
2nd Department of Neurology, Institute Psychiatry and Neurology, Warsaw, Poland.
Gromadzka
Grazyna
G
Członkowska
Anna
A
D000328:Adult; D003300:Copper / Q000097:blood / Q000652:urine; D018450:Disease Progression; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D011149:Pons / Q000473:pathology; D012074:Remission Induction; D019287:Zinc Sulfate / Q000627:therapeutic use
D019287:Zinc Sulfate; D003300:Copper