title: Effect of selenium and copper supplementation on blood metabolic profile in male buffalo (Bubalus bubalis) calves.
abstract: Twenty male buffalo calves (8-9 months, 112.1 +/- 7.69 kg) were divided into four groups of five animals in each and fed diets without (T1) or supplemented with 0.3 ppm selenium (Se) (T2), 0.3 ppm Se + 10 ppm copper (Cu) (T3), and 10 ppm Cu (T4) for 120 days during which blood samples were collected on day 0, 40, 80, and 120. Concentrations of glucose, total protein, urea, uric acid, and creatinine were similar in all the four groups, but the level of globulin was significantly (P < 0.01) increased in groups T2 and T3, leading to reduced levels of albumin and A:G ratio (P < 0.01) in these groups. The level of different serum enzymes viz. lactate dehydrogenase (LDH), alkaline phosphatase (ALP), glutamate pyruvate transaminase (SGPT), and glutamate oxaloacetate transaminase (SGOT) and hormones viz. T3, T4, testosterone and insulin and T4:T3 ratio were similar (P > 0.05) among the four groups. It was deduced that supplementation of 0.3 ppm Se and/or 10.0 ppm of Cu had no effect on blood metabolic profile in buffalo calves, except for an increased globulin level, indicating improved immunity status of these animals.
authors.affiliation: Mineral and Vitamin Nutrition Laboratory, Center of Advanced Studies in Animal Nutrition, Indian Veterinary Research Institute, Izatnagar, -243122, UP, India.
authors.forename: Vishal
authors.initials: V
authors.lastname: Mudgal
authors.forename: Anil Kumar
authors.initials: AK
authors.lastname: Garg
authors.forename: Ram Sharan
authors.initials: RS
authors.lastname: Dass
authors.forename: Vijay Prakash
authors.initials: VP
authors.lastname: Varshney
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001774:Blood Chemical Analysis; D001786:Blood Glucose / Q000187:drug effects; D001798:Blood Proteins / Q000187:drug effects; D002020:Buffaloes / Q000097:blood*; D003300:Copper / Q000494:pharmacology*; D006728:Hormones / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D012643:Selenium / Q000494:pharmacology*
chemical_list: D001786:Blood Glucose; D001798:Blood Proteins; D006728:Hormones; D003300:Copper; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D012643:Selenium