title: [Long-term results of surgical treatment of thymomas at the patients with generalized myasthenia].
abstract: Results of diagnosis and treatment of 150 patients with thymoma and generalized myasthenia are analyzed. The results of examination were registered before surgery, and also in 1, 3, 5 and 10 years after one. It is demonstrated that thymoma is potentially malignant tumor with risk of recurrence and requires long follow-up of patient after operation. Morphologic type and stage of tumor, severity of myasthenia are the main predictors in the prognosis of surgical treatment. Thymomectomy with excision of fatty tissue of anterior mediastinum is absolutely indicated for this severe category of patients, and it decreases the risk of tumor progression. Mortality of patients depends not only on tumor growth or recurrence but also on concomitant myasthenic disorders.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Shevchenko
authors.forename: P S
authors.initials: PS
authors.lastname: Vetshev
authors.forename: A G
authors.initials: AG
authors.lastname: Sanadze
authors.forename: L I
authors.initials: LI
authors.lastname: Ippolitov
authors.forename: D V
authors.initials: DV
authors.lastname: Sidnev
authors.forename: O V
authors.initials: OV
authors.lastname: Abdalova
authors.forename: A S
authors.initials: AS
authors.lastname: Fat'ianova
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000209:etiology / Q000601:surgery*; D016019:Survival Analysis; D013945:Thymoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D013953:Thymus Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome