Resolution of primary acquired melanosis with atypia after minimal mitomycin C treatment.
The most effective dose of mitomycin C (MMC) in the treatment of primary acquired melanosis (PAM) with atypia of the conjunctiva and cornea has yet to be established. This case report describes successful treatment of PAM with atypia with a single four day cycle of 0.02% MMC.
Chen
Jern Yee
JY
Chappell
Angela J
AJ
Klebe
Sonja
S
Mills
Richard A
RA
D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003228:Conjunctiva / Q000473:pathology; D003229:Conjunctival Diseases / Q000188:drug therapy* / Q000473:pathology*; D003315:Cornea / Q000473:pathology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008548:Melanosis / Q000188:drug therapy* / Q000473:pathology*; D016685:Mitomycin / Q000008:administration & dosage / Q000627:therapeutic use*
D000477:Alkylating Agents; D016685:Mitomycin