title: Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route.
abstract: New debromopyrrole-2-aminoimidazolones, debromodispacamide B (1) and debromodispacamide D (2) were isolated from the sponge Agelas mauritiana, collected in the Solomon Islands. A biomimetic one-step reaction from pseudopeptides 5 and 13 in presence of air oxygen and guanidine gave the chiral form of the natural product stereoselectively.
authors.affiliation: Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
authors.forename: Carine
authors.initials: C
authors.lastname: Vergne
authors.forename: Jérôme
authors.initials: J
authors.lastname: Appenzeller
authors.forename: Céline
authors.initials: C
authors.lastname: Ratinaud
authors.forename: Marie-Thérèse
authors.initials: MT
authors.lastname: Martin
authors.forename: Cécile
authors.initials: C
authors.lastname: Debitus
authors.forename: Anne
authors.initials: A
authors.lastname: Zaparucha
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Mourabit
mesh_terms: D047230:Agelas / Q000737:chemistry*; D000818:Animals; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D008386:Marine Biology; D015394:Molecular Structure; D011392:Proline / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D007093:Imidazoles; D011758:Pyrroles; C527921:debromodispacamide B; C527922:debromodispacamide D; C117197:imidazolone; D011392:Proline