title: Stenosis at the area of transposition - an under-recognized complication of transposed brachiobasilic fistulas.
abstract: BACKGROUND
  With an increased focus on native AV fistula creation in hemodialysis patients, a transposed brachiobasilic fistula (tBBF) is becoming an increasingly utilized option. This study describes the outcomes of tBBFs in a chronic hemodialysis population. In particular, we focus on the incidence and location of stenosis, and review the impact of angioplasty on these lesions.
  
  
  METHODS
  A retrospective cohort study using all patients with a tBBF created between January 2001 and December 2004.
  
  
  RESULTS
  Of the 543 fistulas created during the study period, 93 were tBBFs. The mean age of patients was 65 years, 56% were male and 55% were diabetic. Stenosis occurred in 54% (46/85) of fistulas; the location of stenosis in the majority (74%) was at or near the area of basilic vein transposition and 50% of fistulas with stenosis in this location required three or more angioplasties. Primary (unassisted) patency was 42% at one year in this cohort. Secondary patency was 68% at 1 year and 58% and 53% at 2 and 3 years respectively.
  
  
  CONCLUSIONS
  In a cohort of hemodialysis patients who received a tBBF, we describe a reasonable primary and secondary patency rate and a high rate of stenosis at the point of transposition of the basilic vein. Such stenosis usually requires multiple percutaneous or surgical interventions to ensure or reestablish conduit patency. Further study is required regarding the optimal surgical technique, monitoring, and treatment of stenosis of this fistula type including the utility of repeat angioplasty.
authors.affiliation: Division of Nephrology, St. Paul's Hospital, Vancouver, British Columbia, Canada. monicabe@interchange.ubc.ca
authors.forename: M C
authors.initials: MC
authors.lastname: Beaulieu
authors.forename: C
authors.initials: C
authors.lastname: Gabana
authors.forename: C
authors.initials: C
authors.lastname: Rose
authors.forename: P S
authors.initials: PS
authors.lastname: MacDonald
authors.forename: J
authors.initials: J
authors.lastname: Clement
authors.forename: M
authors.initials: M
authors.lastname: Kiaii
mesh_terms: D000368:Aged; D017130:Angioplasty; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects* / Q000706:statistics & numerical data; D001916:Brachial Artery / Q000503:physiopathology / Q000601:surgery*; D015331:Cohort Studies; D003251:Constriction, Pathologic; D005260:Female; D006083:Graft Occlusion, Vascular / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D015994:Incidence; D008297:Male; D006435:Renal Dialysis / Q000706:statistics & numerical data; D012086:Reoperation; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency; D014680:Veins / Q000503:physiopathology / Q000601:surgery*