title: The cell cycle DB: a systems biology approach to cell cycle analysis.
abstract: The cell cycle database is a biological resource that collects the most relevant information related to genes and proteins involved in human and yeast cell cycle processes. The database, which is accessible at the web site http://www.itb.cnr.it/cellcycle, has been developed in a systems biology context, since it also stores the cell cycle mathematical models published in the recent years, with the possibility to simulate them directly. The aim of our resource is to give an exhaustive view of the cell cycle process starting from its building-blocks, genes and proteins, toward the pathway they create, represented by the models.
authors.affiliation: Istituto di Tecnologie Biomediche-Consiglio Nazionale delle Ricerche, via F.lli Cervi 93, Segrate, Milano, Italy. roberta.alfieri@itb.cnr.it
authors.forename: Roberta
authors.initials: R
authors.lastname: Alfieri
authors.forename: Ivan
authors.initials: I
authors.lastname: Merelli
authors.forename: Ettore
authors.initials: E
authors.lastname: Mosca
authors.forename: Luciano
authors.initials: L
authors.lastname: Milanesi
mesh_terms: D002453:Cell Cycle / Q000235:genetics; D018797:Cell Cycle Proteins / Q000378:metabolism*; D030541:Databases, Genetic; D018816:Genes, cdc; D006801:Humans; D020407:Internet; D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D049490:Systems Biology; D014584:User-Computer Interface
chemical_list: D018797:Cell Cycle Proteins; D029701:Saccharomyces cerevisiae Proteins