[Exogenous lipoid pneumonia associated with pulmonary and hepatic sarcoidosis].
BACKGROUND
In a patient with basal alveolar shadowing the diagnosis of exogenous lipoid pneumonia (ELP) requires a past history of chronic ingestion of liquid paraffin and the presence of numerous macrophages containing oil droplets in the bronchial lavage (BL). Additional radiological abnormalities suggest an associated disease, notably infection or cancer, as has been described in the literature.


METHODS
We report the case of a 50 year old woman presenting with alveolar shadowing in the left lung associated with ipsilateral mediastinal nodes and a pleural effusion in addition to two hepatic nodules. As the diagnosis of ELP did not explain the radiological features a thoracotomy and liver biopsies were performed. Histological examination of the hepatic, pulmonary and lymph node biopsies excluded cancer and mycobacterial disease and showed a florid granulomatous foreign body reaction associated with pulmonary and hepatic sarcoidosis. After a 3 month course of oral corticosteroids the mediastinal lymphadenopathy, pleural effusion and hepatic nodules resolved. The patient has maintained her recovery without further treatment for 4 years.


CONCLUSIONS
The final diagnosis was ELP and systemic sarcoidosis with nodular hepatic involvement.
Margery
J
J
Unité Fonctionnelle d'Oncologie Thoracique, Hôpital Tenon, Paris, France. j.margery@free.fr
Martin
C
C
Epaud
C
C
Colombat
M
M
Bazelly
B
B
Milleron
B
B
D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology / Q000473:pathology; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D008875:Middle Aged; D011017:Pneumonia, Lipid / Q000209:etiology* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications*; D017565:Sarcoidosis, Pulmonary / Q000150:complications*