No association between histo-blood group antigens and susceptibility to clinical infections with genogroup II norovirus.
Noroviruses (NoVs) are a leading cause of viral gastroenteritis in humans. In the present study, the association between NoV susceptibility and the ABO histo-blood group was studied during 2 outbreaks of acute gastroenteritis in military units in Israel caused by genogroup II (GII) NoVs. The findings demonstrate that, unlike for genogroup I of NoV, there is no association between the ABO histo-blood group and clinical infection with GII NoVs. This is the largest study to test the association between NoVs, proven clinical infection with GII, and the ABO histo-blood group.
Halperin
Tamar
T
Koret School of Veterinary Medicine, Faculty of Agricultural, Food, and Environmental Sciences, The Hebrew University, Rehovot, Israel.
Vennema
Harry
H
Koopmans
Marion
M
Kahila Bar-Gal
Gila
G
Kayouf
Raid
R
Sela
Tamar
T
Ambar
Ruhama
R
Klement
Eyal
E
D000017:ABO Blood-Group System / Q000235:genetics*; D017250:Caliciviridae Infections / Q000145:classification / Q000453:epidemiology / Q000235:genetics*; D004196:Disease Outbreaks; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D007557:Israel / Q000453:epidemiology; D029322:Norovirus / Q000145:classification* / Q000472:pathogenicity; D010802:Phylogeny
D000017:ABO Blood-Group System