title: Embryonal rhabdomyosarcoma secondary to an open fracture of the tibia: a case report and review of literature.
abstract: Embryonal rhabdomyosarcoma (ERMS) is a highly malignant tumor in children and adolescents. It rarely occurs in adults. A 47-year-old patient presented with ERMS of the muscle flap transplant 20 years after an open type III-comminuted fracture of the lower leg. The affected leg was amputated. The patient refused adjuvant chemotherapy and one year after surgery remains disease-free and in good general condition.
authors.affiliation: Department of Internal Medicine, University Hospital Bonn, Bonn, Germany. ogressner@ukaachen.de
authors.forename: Olav
authors.initials: O
authors.lastname: Gressner
authors.forename: Tilman
authors.initials: T
authors.lastname: Saurbruch
mesh_terms: D000671:Amputation, Surgical; D005593:Fracture Fixation, Internal; D018460:Fractures, Comminuted / Q000150:complications* / Q000601:surgery; D005597:Fractures, Open / Q000150:complications* / Q000601:surgery; D006801:Humans; D007866:Leg; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D017169:Neoplasms, Post-Traumatic / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D018233:Rhabdomyosarcoma, Embryonal / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013978:Tibial Fractures / Q000150:complications* / Q000601:surgery; D013997:Time Factors