title: Survival rate and prognostic factors for patients who underwent surgical procedures for invasive carcinoma of the vulva in Serbia.
abstract: OBJECTIVE
  To determine five-year survival rate and prognostic factors for patients who underwent radical surgery for carcinoma of the vulva.
  
  
  METHODS
  94 women were operated on from 1989 to 1996 at the Clinical Centre of Serbia.
  
  
  RESULTS
  Five-year survival was 78.56% for Stage I, 73.5% for Stage II, for Stage III--14.28%, and for Stage IV--7.14%. Five-year survival rate for tumor size between 2 cm and 5 cm was 57.14%, and for tumors larger than 5 cm, 28.57%. Five-year survival rate was 64.28% if no lymph nodes were involved, 21.43% if there were unilateral metastatic lymph nodes and 14.28% if bilateral lymph nodes had metastatic disease. Histologic grades of the tumor showed that for grade 1, five-year survival was 64.28%, for grade 2, 35.71% and there were no survivors five years after surgery among patients with grade 3 tumor.
  
  
  CONCLUSIONS
  FIGO stage, size of tumor, lymph node involvement and grade of tumor are significant prognostic factors for survival of patients after surgery.
authors.affiliation: Institute of Gynecology and Obstetrics, Clinical Centre of Serbia, Belgrade, Serbia.
authors.forename: T
authors.initials: T
authors.lastname: Bozanovic
authors.forename: A
authors.initials: A
authors.lastname: Ljubic
authors.forename: P
authors.initials: P
authors.lastname: Momcilov
authors.forename: S
authors.initials: S
authors.lastname: Milicevic
authors.forename: T
authors.initials: T
authors.lastname: Mostic
authors.forename: S
authors.initials: S
authors.lastname: Petkovic
mesh_terms: D000368:Aged; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D011379:Prognosis; D015996:Survival Rate; D014846:Vulvar Neoplasms / Q000473:pathology / Q000601:surgery*