Somnambulism induced by quetiapine: two case reports and a review of the literature.
Somnambulism, a previously unreported side effect of quetiapine, is described in two cases. Both cases involved individuals who had no prior or family history of somnambulism and had attention-deficit/hyperactivity disorder. The possible significance of this will also be discussed. Somnambulism is a common parasomnia that reflects an impairment in the normal mechanisms of arousal from sleep in which motor behaviors are activated without full consciousness. Motor behaviors are initiated during deep non-rapid eye movement or slow-wave sleep (stages 3-4), and may be limited to relatively simple manifestations, such as sitting up, fumbling with objects or bedclothes, or mumbling.
Hafeez
Zeba Hasan
ZH
Department of Psychiatry, University of Nevada School of Medicine, Las Vegas, Las Vegas, NV, USA. zebahafeez@hotmail.com
Kalinowski
Constance M
CM
D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003987:Dibenzothiazepines / Q000009:adverse effects*; D006801:Humans; D035002:Lower Extremity / Q000503:physiopathology; D008274:Magnesium; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D000069348:Quetiapine Fumarate; D012640:Seizures / Q000503:physiopathology; D013009:Somnambulism / Q000139:chemically induced*
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D008274:Magnesium