Targeted antibodies in dairy-based products.
Bovine colostrum contains immunoglobulins that provide the newborn calf with protection against microbial infections until its own immune system matures. The concentration of antibodies in colostrum against pathogens can be raised by immunizing cows with pathogens or their antigens. Bovine colostrum-based immune milk products have proven efficacy in prophylaxis and treatment against various infectious diseases in humans such as diarrheal diseases caused by various pathogens like E. coli and rotavirus. Still, future attempts are needed to increase the yield and the concentration of antibodies in order to achieve full protection.
Hammarström
Lennart
L
Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, SE-141 86, Stockholm, Sweden. lennart.hammarstrom@ki.se
Weiner
Carina Krüger
CK
D000818:Animals; D000906:Antibodies / Q000276:immunology* / Q000302:isolation & purification / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000276:immunology; D003126:Colostrum / Q000276:immunology*; D018849:Controlled Clinical Trials as Topic; D003457:Cryptosporidiosis / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D012400:Rotavirus Infections / Q000188:drug therapy / Q000276:immunology
D000906:Antibodies