title: Nephrotic syndrome due to focal segmental glomerulosclerosis: long-term outcomes.
abstract: Lessons learned over 25 years from treating focal segmental glomerulosclerosis (FSGS) in a regional pediatric nephrology program will be reviewed. In a cohort of children with biopsy-proven FSGS, consisting of a large percentage of African-American patients, the clinical characteristics and long-term outcomes are different from previously published data on mostly white children with the same condition. Because Asian and African children with nephrotic syndrome have the same higher incidence of FSGS, it is possible that Chinese children with FSGS have clinical characteristics, therapeutic responses, and long-term outcomes similar to African-American children as reviewed in this article.
authors.affiliation: College of Medicine, University of Vermont, The Barbara Bush Children's Hospital, Maine Medical Center, Portland, Maine 04102-3175, USA. chanj@mmc.org
authors.forename: James Cm
authors.initials: JC
authors.lastname: Chan
mesh_terms: D001741:Black or African American; D002648:Child; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009404:Nephrotic Syndrome / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis