Lysis of cyanobacteria with volatile organic compounds.
One of bacteria collected from Lake Sagami, Japan, Brevibacillus sp., was found to have a lytic activity of cyanobacteria, but did not produce active compounds. Instead, the co-culturing of Microcystis with the Brevibacillus sp. enhanced the production of two volatile compounds, beta-cyclocitral and 3-methyl-1-butanol, and the former had a characteristic lytic activity. It was confirmed that these volatile compounds were derived from the cyanobacteria themselves. beta-Ionone, geosmin and 2-methylisoborneol derived from cyanobacteria and similar volatile compounds, terpenoids, produced by plants also had a lytic activity. The minimum inhibitory concentration values of the cyanobacterial metabolites were estimated to be higher than those of compounds from plants except for a few compounds. Among them, beta-cyclocitral only produced a characteristic color change of culture broth from green to blue. This color change is similar to the phenomenon observed when a sudden decline in growth of cyanobacteria begins in a natural environment.
Ozaki
Keiko
K
Graduate School of Environmental and Human Science, Meijo University, Tempaku, Nagoya 468-8503, Japan. q0491502@ccmailg.meijo-u.ac.jp
Ohta
Akemi
A
Iwata
Chieko
C
Horikawa
Aki
A
Tsuji
Kiyomi
K
Ito
Emiko
E
Ikai
Yoshitomo
Y
Harada
Ken-Ichi
K
D000447:Aldehydes / Q000737:chemistry / Q000494:pharmacology; D001433:Bacteriolysis / Q000187:drug effects*; D001892:Camphanes / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000458:Cyanobacteria / Q000187:drug effects* / Q000378:metabolism; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology; D007564:Japan; D015394:Molecular Structure; D009284:Naphthols / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D045792:Norisoprenoids / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D009930:Organic Chemicals / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000439:Pentanols / Q000737:chemistry / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D014835:Volatilization
D000447:Aldehydes; D001892:Camphanes; D004224:Diterpenes; D009284:Naphthols; D045792:Norisoprenoids; D009930:Organic Chemicals; D000439:Pentanols; D013729:Terpenes; C005536:2-methylisoborneol; C516118:beta-cyclocitral; C008157:beta-ionone; C029683:isopentyl alcohol; C001278:geosmin