title: Metal vinylidenes as catalytic species in organic reactions.
abstract: Organic vinylidene species have found limited use in organic synthesis owing to their inaccessibility. In contrast, metal vinylidenes are much more stable and may be readily accessed through transition-metal activation of terminal alkynes. These electrophilic species may be trapped by a number of nucleophiles. Additionally, metal vinylidenes can participate in pericyclic reactions and processes that involve migration of a metal ligand to the vinylidene species. This Focus Review addresses the reactions and applications of metal vinylidenes in organic synthesis.
authors.affiliation: Department of Chemistry, Stanford University, Stanford, CA 94305, USA. bmtrost@stanford.edu
authors.forename: Barry M
authors.initials: BM
authors.lastname: Trost
authors.forename: Andrew
authors.initials: A
authors.lastname: McClory
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000737:chemistry*
chemical_list: D005030:Ethylenes; D008024:Ligands; D008670:Metals; D002244:Carbon