title: Antimicrobial potential of Glycyrrhiza glabra roots.
abstract: The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.
authors.affiliation: Genetic Resources and Biotechnology Division, Central Institute of Medicinal and Aromatic Plants (CSIR), Kukrail Picnic Spot Road, P.O. CIMAP, Lucknow 226015, India.
authors.forename: Vivek K
authors.initials: VK
authors.lastname: Gupta
authors.forename: Atiya
authors.initials: A
authors.lastname: Fatima
authors.forename: Uzma
authors.initials: U
authors.lastname: Faridi
authors.forename: Arvind S
authors.initials: AS
authors.lastname: Negi
authors.forename: Karuna
authors.initials: K
authors.lastname: Shanker
authors.forename: J K
authors.initials: JK
authors.lastname: Kumar
authors.forename: Neha
authors.initials: N
authors.lastname: Rahuja
authors.forename: Suaib
authors.initials: S
authors.lastname: Luqman
authors.forename: Brijesh S
authors.initials: BS
authors.lastname: Sisodia
authors.forename: Dharmendra
authors.initials: D
authors.lastname: Saikia
authors.forename: M P
authors.initials: MP
authors.lastname: Darokar
authors.forename: Suman P S
authors.initials: SP
authors.lastname: Khanuja
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006035:Glycyrrhiza / Q000737:chemistry*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts