[Therapeutical efficacy of routine intra-aortic balloon pump support in patients with high-risk acute myocardial infarction undergoing percutaneous coronary intervention].
OBJECTIVE
To assess the value of routine intra-aortic balloon pump (IABP) support in patients with high-risk acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI).


METHODS
The clinical data of 41 patients with high-risk AMI undergoing emergency PCI with routine IABP support were retrospectively reviewed, and 38 patients paired with the former group receiving emergency PCI for high-risk AMI without IABP support at the same time were included as the control group. Thirty days after the operation, the two groups were compared for myocardial ischemic events, left ventricular function and major adverse cardiac events (MACE).


RESULTS
Patients receiving IABP support had a significantly lower incidence of myocardial ischemic events than those without IABP (4.9% vs 15.8%, P<0.05), and showed greater improvement in the left ventricular function. Significant differences were also observed in the mortality rate, incidence of reinfarction and revascularization rate between the two groups, but not in the rate of MACE.


CONCLUSIONS
Patients undergoing PCI for high-risk acute AMI can benefit from routine IABP support in terms of improvement of left ventricular function and reduce myocardial ischemic events and the rate of MACE. These results, however, still await further confirmation by large-scale clinical trials.
Chen
Jun
J
Department of Cardiology, Foshan First People's Hospital, Foshan 528000, China. szchenjun@medmail.com.cn
Yang
Xi-li
XL
Zhou
Zhao-lun
ZL
Li
Jian-min
JM
Tan
Hai-bin
HB
D015906:Angioplasty, Balloon, Coronary; D005260:Female; D006801:Humans; D015994:Incidence; D007423:Intra-Aortic Balloon Pumping / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D017202:Myocardial Ischemia; D012189:Retrospective Studies; D016896:Treatment Outcome; D016277:Ventricular Function, Left