title: Magnetic dispersion of the late repolarization in Brugada syndrome.
abstract: BACKGROUND
  Magnetocardiography (MCG) is a new noninvasive modality for recording cardiac depolarization and repolarization and was used in the present study to evaluate abnormalities in patients with Brugada syndrome (BS).
  
  
  RESULTS
  The MCG findings of 10 BS, 21 right bundle branch block (RBBB), and 34 normal patients were compared. On the horizontal spatiotemporal activation graph (STAG), the r' waves were more frequently located on the right side in the RBBB than in the normal (p=0.001) or BS groups (p=0.001). The maximum current angles of the r' wave fell into the northwest axis in all BS patients as compared to having a right axis deviation in 19 of 21 RBBB patients (90.4%, p=0.001). In the magnetic field and current density vector maps during late repolarization, the BS group had a non-dipole pattern more frequently and a higher number of poles compared with the normal (p=0.001) and RBBB groups (p=0.001).
  
  
  CONCLUSIONS
  During depolarization, the horizontal STAG location and maximum current angle of the r' wave were beneficial in differentiating BS from RBBB and normal. The magnetic dispersion was a more frequently observed finding in BS patients than in RBBB and normal patients during late repolarization.
authors.affiliation: Cardiology Division, Department of Internal Medicine, Yonsei University Medical College.
authors.forename: Boyoung
authors.initials: B
authors.lastname: Joung
authors.forename: Kiwoong
authors.initials: K
authors.lastname: Kim
authors.forename: Yong-Ho
authors.initials: YH
authors.lastname: Lee
authors.forename: Hyukchan
authors.initials: H
authors.lastname: Kwon
authors.forename: Hyun Kyoon
authors.initials: HK
authors.lastname: Lim
authors.forename: Tae-Uen
authors.initials: TU
authors.lastname: Kim
authors.forename: Young-Guk
authors.initials: YG
authors.lastname: Ko
authors.forename: Moonhyoung
authors.initials: M
authors.lastname: Lee
authors.forename: Namsik
authors.initials: N
authors.lastname: Chung
authors.forename: Sungsoon
authors.initials: S
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D053840:Brugada Syndrome / Q000175:diagnosis*; D002037:Bundle-Branch Block / Q000175:diagnosis; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D053798:Magnetocardiography / Q000379:methods* / Q000592:standards; D008297:Male; D008875:Middle Aged