title: Association of urgency symptoms with self-rated health, mood and functioning in an older population.
abstract: OBJECTIVE
  Lower urinary tract symptoms (LUTS) with comorbidities are common in old age. The aim here was to investigate the associations of urgency symptoms with self-rated health, mood and functioning in a random older population adjusted for comorbid conditions.
  
  
  METHODS
  A population-based cross-sectional survey was made involving 343 people (159 men and 184 women) aged 70 years and over. LUTS were categorized as symptoms with or without urgency. Perceived inconvenience from LUTS, self-rated health, mood, social activity and activities of daily living (ADL), instrumental activities of daily living (IADL) and mobility disability were the outcome measures. Ageand gender-adjusted and multivariate logistic regression models were constructed in order to examine the associations of urgency and non-urgency symptoms with the outcomes. The covariates were age, gender, and self-reported cardiovascular, musculoskeletal, neurological and other chronic diseases.
  
  
  RESULTS
  Perceived inconvenience from urgency symptoms was more frequent than that from non-urgency symptoms (64% vs 20%, p<0.001). In the age- and gender-adjusted logistic regression models, LUTS with urgency were associated with poor self-rated health (OR [odds ratio] 2.35; 95% CI [confidence interval] 1.06-5.20), depressive mood (OR 7.29; 95% CI 2.91-18.30), ADL (OR 2.33; 95% CI 1.10-4.92), IADL (OR 2.16; 95% CI 1.19-3.92) and mobility disability (OR 2.44; 95% CI 1.37-4.36). LUTS without urgency were associated with depressive mood (OR 5.02; 95% CI 1.97-12.82) and mobility disability (OR 1.97; 95% CI 1.10-3.53). In the multivariate analyses in which comorbid conditions were added to the model, the associations of non-urgency and urgency symptoms persisted only with depressive mood (OR 4.00; 95% CI 1.52-10.53 and OR 6.16; 95% CI 2.39-15.84, respectively).
  
  
  CONCLUSIONS
  Urgency symptoms are associated with poor self-rated health, depressive mood and disability in older people. There is an independent association between both urgency and non-urgency LUTS and depressive mood. A careful assessment of the mental state of older individuals with LUTS is warranted.
authors.affiliation: Geriatric Unit, South-Ostrobothnia Hospital District, Seinäjoki Central Hospital, Seinäjoki, Finland. maria.nuotio@netikka.fi
authors.forename: Maria
authors.initials: M
authors.lastname: Nuotio
authors.forename: Teuvo L J
authors.initials: TL
authors.lastname: Tammela
authors.forename: Tiina
authors.initials: T
authors.lastname: Luukkaala
authors.forename: Marja
authors.initials: M
authors.lastname: Jylhä
mesh_terms: D000203:Activities of Daily Living; D000339:Affect; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D006304:Health Status; D006801:Humans; D008297:Male; D051346:Mobility Limitation; D012737:Sex Factors; D012934:Social Isolation; D014555:Urination Disorders / Q000453:epidemiology* / Q000523:psychology