title: A review of the current literature on management of halitosis.
abstract: Halitosis is an unpleasant or offensive odour, emanating from the oral cavity. In approximately 80% of all cases, halitosis is caused by microbial degradation of oral organic substrates. Major degradation products are volatile sulphur-containing compounds. In this review, the available management methods of halitosis and their effectiveness and significance are presented and discussed. Undoubtedly, the basic management is mechanically reducing the amount of micro-organisms and substrates in the oral cavity. Masking products are not, and antimicrobial ingredients in oral healthcare products are only temporary effective in reducing micro-organisms or their substrates. Good short-term results were reported with chlorhexidine. Triclosan seems less effective, essential oils and cetylpyridinium chloride are only effective up to 2 or 3 h. Metal ions and oxidizing agents, such as hydrogen peroxide, chlorine dioxide and iminium are active in neutralizing volatile sulphur-containing compounds. Zinc seems to be an effective safe metal at concentrations of at least 1%. The effectiveness of active ingredients in oral healthcare products is dependent on their concentration and above a certain concentration the ingredients can have unpleasant side effects. Tonsillectomy might be indicated if (i) all other causes of halitosis are managed properly; (ii) halitosis still persists and (iii) crypts in tonsils are found to contain malodorous substrates.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Special Dental Care, Erasmus University Medical Center, Rotterdam, The Netherlands. a.vandenbroek@erasmusmc.nl
authors.forename: A M W T
authors.initials: AM
authors.lastname: van den Broek
authors.forename: L
authors.initials: L
authors.lastname: Feenstra
authors.forename: C
authors.initials: C
authors.lastname: de Baat
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001419:Bacteria / Q000378:metabolism; D015169:Colony Count, Microbial; D004338:Drug Combinations; D006209:Halitosis / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D009067:Mouthwashes / Q000627:therapeutic use; D009910:Oral Hygiene; D016877:Oxidants / Q000627:therapeutic use; D013457:Sulfur Compounds / Q000378:metabolism; D014068:Tonsillectomy
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D009067:Mouthwashes; D016877:Oxidants; D013457:Sulfur Compounds