Transcription: a mechanism for short-term memory.
Yeast growing for a considerable time in glucose 'remember' a previous exposure to galactose, the inducer of its galactose-utilization (GAL) genes. This memory is conveyed by a cytoplasmically transmitted galactokinase working as a signal transducer.
Ptashne
Mark
M
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 595, New York, New York 10021, USA. m-ptashne@ski.mskcc.org
D044127:Epigenesis, Genetic; D005690:Galactose / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D005947:Glucose / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction; D014158:Transcription, Genetic / Q000502:physiology*
D005947:Glucose; D005690:Galactose