title: Engineering design methodology for bio-mechatronic products.
abstract: Four complex biotechnology products/product systems (a protein purification system, a bioreactor system, a surface plasmon resonance biosensor, and an enzymatic glucose analyzer) are analyzed using conceptual design principles. A design model well-known in mechanical system design, the Hubka-Eder (HE) model, is adapted to biotechnology products that exemplify combined technical systems of mechanical, electronic, and biological components, here referred to as bio-mechatronic systems. The analysis concludes that an extension of the previous HE model with a separate biological systems entity significantly contributes to facilitating the functional and systematic analyses of bio-mechatronic systems.
authors.affiliation: Division of Assembly Technology/IEI, Linköping University, 581 83 Linköping, Sweden.
authors.forename: Micael
authors.initials: M
authors.lastname: Derelöv
authors.forename: Jonas
authors.initials: J
authors.lastname: Detterfelt
authors.forename: Mats
authors.initials: M
authors.lastname: Björkman
authors.forename: Carl-Fredrik
authors.initials: CF
authors.lastname: Mandenius
mesh_terms: D019149:Bioreactors; D015374:Biosensing Techniques; D001709:Biotechnology / Q000295:instrumentation* / Q000379:methods*; D008962:Models, Theoretical; D020349:Surface Plasmon Resonance