Detecting and localizing the foci in human epileptic seizures.
We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to analyze the interictal phase synchrony between such electrodes is introduced and developed with the aim of detecting and localizing the foci of the epileptic seizures. We evaluate the method by comparing the results of surgery to the localization predicted here. We find an indication of good correspondence between the success or failure in the surgery and the agreement between our identification and the regions actually operated on.
Ben-Jacob
Eshel
E
School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel.
Boccaletti
Stefano
S
Pomyalov
Anna
A
Procaccia
Itamar
I
Towle
Vernon L
VL
D000293:Adolescent; D001921:Brain / Q000473:pathology; D002648:Child; D004566:Electrodes; D004569:Electroencephalography / Q000295:instrumentation* / Q000379:methods; D004594:Electrophysiology / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis*; D004867:Equipment Design; D005260:Female; D006801:Humans; D009991:Oscillometry / Q000379:methods; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013997:Time Factors