[Validation the haplotype polymorphisms of the DXS7424-DXS101 on X-chromosome].
OBJECTIVE
To validate the genetic characteristics and distribution of DXS7424-DXS101 on X chromosome in Han population.


METHODS
DXS7424 and DXS101 loci were genotyped by PCR, PAGE and silvers stain methods. Their genetic parameters were analyzed by Arlequin software.


RESULTS
There were 37 haplotypes detected in 151 Han unrelated males. The frequencies ranged from 0.0066 to 0.1391, with a GD value of 0.9453 and a DP value of 0.9389. Haplotypes 16-23 were the most common haplotypes in Han population.


CONCLUSIONS
Analysis of combined DXS7424 and DXS101 haplotypes appears to be a powerful means in population genetics and forensic practice for determination of identity and paternity.
Yu
Bing
B
Key Laboratory of Forensic Sciences, National Ministry of Health, Xi'an Jiaotong University, Xi'an, 710061 China. yubing@mail.xjtu.edu.cn
Tuo
Ya
Y
Gui
Hong-sheng
HS
Li
Sheng-bin
SB
D000483:Alleles; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D005787:Gene Frequency; D008040:Genetic Linkage / Q000235:genetics; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences