Psychometric properties of WHOQOL-BREF-THAI in patients with HIV/AIDS.
OBJECTIVE
To assess reliability and validity of the Thai abbreviated version of World Health Organization quality of life (WHOQOL-BREF-THAI) in HIV/AIDS patients.


METHODS
The present study is descriptive research. Data were purposefully collected from 120 HIV/AIDS outpatients at Bamrasnaradura Infectious Disease Institute, Thailand, during September-December 2004.


RESULTS
Cronbach's alpha ranged from 0.61 to 0.81 across domains. Exploratory factor analysis identified four major domains: physical, psychological, social and environmental domains, corresponding to the four WHOQOL-BREF domains. The four domain scores correlated positively with general health satisfaction and overall quality of life questions (all p < 0.01 except general health & social domain p < 0.05), and correlated negatively with the frequency and severity of HIV symptoms (all p < 0.01). The four domain scores discriminated between patients with higher and lower frequency and severity of HIV symptoms (all p < 0.01).


CONCLUSIONS
The present study shows that WHOQOL-BREF THAI can be a good generic health-related quality of life instrument in HIV/AIDS patients.
Sakthong
Phantipa
P
Faculty of Pharmaceutical Sciences, Chulalongkorn University, Prayathai Rd, Pathumwan, Bangkok 10330, Thailand. Phantipa.S@chula.ac.th
Schommer
Jon C
JC
Gross
Cynthia R
CR
Sakulbumrungsil
Rungpetch
R
Prasithsirikul
Wisit
W
D000328:Adult; D005163:Factor Analysis, Statistical; D005260:Female; D015658:HIV Infections / Q000523:psychology*; D006304:Health Status; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D017060:Patient Satisfaction; D011581:Psychological Tests; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D013785:Thailand