Two cases of post-radiation osteosarcoma of the sacrum after pelvic irradiation for uterine cervical cancer.
BACKGROUND
Post-radiation pelvic bone sarcoma can result as a long-term sequela of pelvic irradiation for uterine cervical cancer.


METHODS
A 59-year-old woman who had received pelvic irradiation for Stage IIB uterine cervical cancer 16 years before was diagnosed as having post-radiation osteosarcoma of the sacrum. Another 66-year-old woman who had received pelvic irradiation for Stage IIIB uterine cervical cancer seven years previously was also diagnosed as having pleomorphic sarcoma of the sacrum.


CONCLUSIONS
When a bone lesion is observed at a previously irradiated field, post-radiation sarcoma should be considered and differentiated from bone metastases.
Noh
J M
JM
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Huh
S J
SJ
D000368:Aged; D001859:Bone Neoplasms / Q000209:etiology / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D012516:Osteosarcoma / Q000209:etiology / Q000473:pathology / Q000556:secondary*; D011878:Radiotherapy / Q000009:adverse effects; D012447:Sacrum / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy*