Hepatocellular carcinoma associated with recreational anabolic steroid use.
A 35-year-old male bodybuilder was found to have a hepatocellular carcinoma (HCC) arising in a pre-existing hepatic adenoma following recreational anabolic steroid use. Given the widespread use of recreational anabolic steroids, another potentially life-threatening complication is highlighted in addition to the more commonly recognised hepatic adenoma. Malignant transformation to HCC from a pre-existing hepatic adenoma confirmed by immunohistochemical study has previously not been reported in athletes taking anabolic steroids. Further studies using screening programmes to identify high-risk individuals are recommended.
Gorayski
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Peter Gorayski, Department of General Medicine, Flinders Medical Centre, Flinders Drive, Bedford Park, SA, Australia. peter.gorayski@gmail.com
Thompson
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Subhash
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Thomas
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D000236:Adenoma / Q000473:pathology; D000328:Adult; D045930:Anabolic Agents / Q000009:adverse effects*; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D014891:Weight Lifting
D045930:Anabolic Agents