title: The physical therapy clinical research network (PTClinResNet): methods, efficacy, and benefits of a rehabilitation research network.
abstract: This article describes the vision, methods, and implementation strategies used in building the infrastructure for PTClinResNet, a clinical research network designed to assess outcomes for health-related mobility associated with evidence-based physical therapy interventions across and within four different disability groups. Specific aims were to (1) create the infrastructure necessary to develop and sustain clinical trials research in rehabilitation, (2) generate evidence to evaluate the efficacy of resistance exercise-based physical interventions designed to improve muscle performance and movement skills, and (3) provide education and training opportunities for present and future clinician-researchers and for the rehabilitation community at-large in its support of evidence-based practice. We present the network's infrastructure, development, and several examples that highlight the benefits of a clinical research network. We suggest that the network structure is ideal for building research capacity and fostering multisite, multiinvestigator clinical research projects designed to generate evidence for the efficacy of rehabilitation interventions.
authors.affiliation: Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, Los Angeles, California 90089-9006, USA.
authors.forename: Carolee
authors.initials: C
authors.lastname: Winstein
authors.forename: Patricia
authors.initials: P
authors.lastname: Pate
authors.forename: Tingting
authors.initials: T
authors.lastname: Ge
authors.forename: Carolyn
authors.initials: C
authors.lastname: Ervin
authors.forename: James
authors.initials: J
authors.lastname: Baurley
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Sullivan
authors.forename: Samantha J
authors.initials: SJ
authors.lastname: Underwood
authors.forename: Eileen G
authors.initials: EG
authors.lastname: Fowler
authors.forename: Sara
authors.initials: S
authors.lastname: Mulroy
authors.forename: David A
authors.initials: DA
authors.lastname: Brown
authors.forename: Kornelia
authors.initials: K
authors.lastname: Kulig
authors.forename: James
authors.initials: J
authors.lastname: Gordon
authors.forename: Stanley P
authors.initials: SP
authors.lastname: Azen
mesh_terms: D002140:California; D003299:Cooperative Behavior; D006801:Humans; D020407:Internet; D015337:Multicenter Studies as Topic; D026761:Physical Therapy Specialty / Q000458:organization & administration*; D016032:Randomized Controlled Trials as Topic; D012106:Research / Q000458:organization & administration*; D012955:Societies, Medical / Q000458:organization & administration*