title: Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders.
authors.affiliation: Department of Dermatology, University of California, VAMC Metabolism 111F, 4150 Clement Street, San Francisco, CA 94121, USA. schmuthm@derm.ucsf.edu
authors.forename: Matthias
authors.initials: M
authors.lastname: Schmuth
authors.forename: Robert
authors.initials: R
authors.lastname: Gruber
authors.forename: Peter M
authors.initials: PM
authors.lastname: Elias
authors.forename: Mary L
authors.initials: ML
authors.lastname: Williams
mesh_terms: D004817:Epidermis / Q000502:physiology*; D000091344:Filaggrin Proteins; D006801:Humans; D007057:Ichthyosis / Q000145:classification / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology*; D007381:Intermediate Filament Proteins / Q000235:genetics / Q000502:physiology; D053556:Keratin-1 / Q000235:genetics; D053550:Keratin-10 / Q000235:genetics; D015603:Keratinocytes / Q000502:physiology*; D008565:Membrane Proteins / Q000235:genetics; D009154:Mutation; D053491:Proteinase Inhibitory Proteins, Secretory / Q000235:genetics; D000074163:Serine Peptidase Inhibitor Kazal-Type 5; D011503:Transglutaminases / Q000172:deficiency / Q000235:genetics
chemical_list: D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins; D053556:Keratin-1; D008565:Membrane Proteins; D053491:Proteinase Inhibitory Proteins, Secretory; C120650:SPINK5 protein, human; D000074163:Serine Peptidase Inhibitor Kazal-Type 5; C064554:loricrin; D053550:Keratin-10; D011503:Transglutaminases; C105804:transglutaminase 1