title: Tracking and prediction of arterial blood pressure from childhood to young adulthood in 868 patients with type 1 diabetes: a multicenter longitudinal survey in Germany and Austria.
abstract: OBJECTIVE
  Arterial blood pressure was followed in 868 patients with type 1 diabetes aged 6.0-19.9 years in 95 centers in Germany and Austria.
  
  
  METHODS
  European blood pressure reference data for 28,043 children and adolescents were used with respect to age and sex. Data were stratified into three groups: prepubertal, pubertal, and postpubertal.
  
  
  RESULTS
  Up to 4% of the participants in the younger age-groups and 13.9% of the postpubertal patients exhibited blood pressure values >97th centile. Blood pressure levels correlated with A1C level and BMI Z score. Tracking of blood pressure revealed that children with elevated blood pressure had higher blood pressure in adolescence and young adulthood.
  
  
  CONCLUSIONS
  Patients with higher blood pressure in childhood showed elevated blood pressure later in life. We need to focus on the diagnosis of hypertension in children with type 1 diabetes and to study the efficacy of early intervention.
authors.affiliation: Children's and Adolescents' Hospital, University of Erlangen-Nuremberg, D-91054 Erlangen, Germany. ina.knerr@uk-erlangen.de
authors.forename: Ina
authors.initials: I
authors.lastname: Knerr
authors.forename: Axel
authors.initials: A
authors.lastname: Dost
authors.forename: Rudolf
authors.initials: R
authors.lastname: Lepler
authors.forename: Klemens
authors.initials: K
authors.lastname: Raile
authors.forename: Edith
authors.initials: E
authors.lastname: Schober
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Rascher
authors.forename: Reinhard W
authors.initials: RW
authors.lastname: Holl
mesh_terms: D000293:Adolescent; D000328:Adult; D001317:Austria / Q000453:epidemiology; D001794:Blood Pressure / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000453:epidemiology*; D003971:Diastole; D005260:Female; D005500:Follow-Up Studies; D005858:Germany / Q000453:epidemiology; D006306:Health Surveys; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D011237:Predictive Value of Tests; D013599:Systole