title: Cationic palladium(II)-catalyzed stereoselective glycosylation with glycosyl trichloroacetimidates.
abstract: The development of a new method for stereoselective glycosylation with glycosyl trichloroacetimidate donors employing cationic palladium(II), Pd(CH(3)CN)(4)(BF(4))(2), is described. This process employs Pd(CH(3)CN)(4)(BF(4))(2) as an efficient activator, providing access to a variety of disaccharides and glycopeptides. This reaction is highly stereoselective and proceeds under mild conditions with low catalyst loading. Interestingly, this palladium catalysis directs beta-glucosylations in the absence of classical neighboring group participation.
authors.affiliation: Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, USA.
authors.forename: Jaemoon
authors.initials: J
authors.lastname: Yang
authors.forename: Colleen
authors.initials: C
authors.lastname: Cooper-Vanosdell
authors.forename: Enoch A
authors.initials: EA
authors.lastname: Mensah
authors.forename: Hien M
authors.initials: HM
authors.lastname: Nguyen