Gaussian representation of high-intensity focused ultrasound beams.
A method for fast numerical simulation of high-intensity focused ultrasound beams is derived. The method is based on the frequency-domain representation of the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation, and assumes for each harmonic a Gaussian transverse pressure distribution at all distances from the transducer face. The beamwidths of the harmonics are constrained to vary inversely with the square root of the harmonic number, and as such this method may be viewed as an extension of a quasilinear approximation. The technique is capable of determining pressure or intensity fields of moderately nonlinear high-intensity focused ultrasound beams in water or biological tissue, usually requiring less than a minute of computer time on a modern workstation. Moreover, this method is particularly well suited to high-gain simulations since, unlike traditional finite-difference methods, it is not subject to resolution limitations in the transverse direction. Results are shown to be in reasonable agreement with numerical solutions of the full KZK equation in both tissue and water for moderately nonlinear beams.
Soneson
Joshua E
JE
Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland 20993, USA. joshua.soneson@fda.hhs.gov
Myers
Matthew R
MR
D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D008962:Models, Theoretical; D016011:Normal Distribution; D014464:Ultrasonic Therapy