title: [Ghrelin and its influence on cardiovascular system].
abstract: Ghrelin plays an important role in regulation of feeding behavior and energy homeostasis. It stimulates the release of growth hormone (GH) from pituitary and also activates its receptors expressed e.g. in the heart, aorta and coronary arteries. Ghrelin besides its orexigenic influences also improves left ventricular function in men and rats. It inhibits both apoptosis and expression of proinflammatory cytokines by cardiomyocytes and endothelial cells. Based on the contemporary .literature we present the influence of ghrelin on cardiovascular diseases and atherosclerosis.
authors.affiliation: Powiatowego Centrum Zdrowia w Kamiennej Górze Szpitala Powiatowego Spółka z o.o. NZOZ. dolvita@mp.pl
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dubiński
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Zdrojewicz
mesh_terms: D000818:Animals; D002319:Cardiovascular System / Q000378:metabolism*; D004734:Energy Metabolism / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D054439:Ghrelin / Q000502:physiology*; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D051381:Rats
chemical_list: D054439:Ghrelin; D013006:Growth Hormone