[The influence of parathyroidectomy on phagocytic capability of polymorphonuclear cells in patients on hemodialysis].
Having in mind the fact, that in patients with secondary hyperparathyroidism induced by chronic renal failure, phagocytic capability of leukocytes is supressed, we attempted to investihate the role of parathormone in it. The study included 6 hemodialysed and 5 healthy volunteers. The degree of phagocyosis was determined according to the HBT test on polymorphonuclear leukocytes (PMNL), before, and 7 and 60 days following the subtotal parathyroodectomy. In all patients, value of NBT test was highly significantly decreased. Following the surgical procedure the increase was significant, however it remained significantly lower when compared to the controls. We have concluded that inhibitory role of parathormone in PMNL phagocytosis was significant, however, in such patients the inhibition was contributed by other factors, as well.
Stosović
R
R
Djukanović
Lj
Lj
Marković
Lj
Lj
Adanja-Grujić
G
G
Tanurdzić
S
S
D000328:Adult; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology / Q000601:surgery*; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D010281:Parathyroid Hormone / Q000502:physiology; D016105:Parathyroidectomy; D010587:Phagocytosis; D006435:Renal Dialysis
D010281:Parathyroid Hormone