Green and efficient synthesis of quinoxaline derivatives via ceric ammonium nitrate promoted and in situ aerobic oxidation of alpha-hydroxy ketones and alpha-keto oximes in aqueous media.
The direct conversion of alpha-hydroxy ketones and alpha-keto oximes into quinoxaline derivatives in the presence of a catalytic amount of ceric ammonium nitrate via metal-catalyzed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines in water as a green and efficient reaction media, is reported.
Shaabani
Ahmad
A
Department of Chemistry, Shahid Beheshti University, Tehran, Iran. a-shaabani@cc.sbu.ac.ir
Maleki
Ali
A
D002563:Cerium / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010091:Oximes / Q000737:chemistry*; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry
D007659:Ketones; D010091:Oximes; D011810:Quinoxalines; D014867:Water; D002563:Cerium; C004653:ceric ammonium nitrate