Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma.
We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.
Farre
Lourdes
L
Laboratory of Immunoregulation and Microbiology, Centro de Pesquisa Conçalo Moniz-Fundação Oswaldo Cruz, Bahia, Brazil. lourdesfarre@hotmail.com
de Oliveira
Maria de Fátima Paim
Mde F
Primo
Janeusa
J
Vandamme
Anne-Mieke
AM
Van Weyenbergh
Johan
J
Bittencourt
Achiléa L
AL
D002648:Child; D003872:Dermatitis / Q000134:cerebrospinal fluid / Q000821:virology*; D005260:Female; D015481:HTLV-I Antibodies / Q000134:cerebrospinal fluid; D015368:Human T-lymphotropic virus 1 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000134:cerebrospinal fluid / Q000821:virology*; D015493:Paraparesis, Tropical Spastic / Q000134:cerebrospinal fluid / Q000821:virology*; D016133:Polymerase Chain Reaction
D015481:HTLV-I Antibodies