title: In vitro enhancement by CpG ODN of phagocytic activity of rainbow trout head kidney phagocytes against fish pathogen Vibrio ordalii, but not against polystyrene particles.
abstract: Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity against Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.
authors.affiliation: Laboratory of Veterinary Immunology, Course of Veterinary Science, Graduate School of Life and Environmental Science, Osaka Prefecture University, Sakai, Osaka, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakatani
authors.forename: Tadashi
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Shinobu
authors.initials: S
authors.lastname: Watarai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kodama
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005393:Fish Diseases / Q000382:microbiology; D007668:Kidney / Q000166:cytology; D009838:Oligodeoxyribonucleotides / Q000494:pharmacology*; D017686:Oncorhynchus mykiss; D010586:Phagocytes / Q000187:drug effects*; D010587:Phagocytosis / Q000187:drug effects*; D011137:Polystyrenes; D014733:Vibrio
chemical_list: D000900:Anti-Bacterial Agents; C408982:CPG-oligonucleotide; D009838:Oligodeoxyribonucleotides; D011137:Polystyrenes