Intermolecular Cope-type hydroamination of alkynes using hydrazines.
Metal-free, intermolecular hydroaminations are performed upon heating aryl acetylenes and MeNHNH(2) at 140 degrees C, with preferential formation of the linear, "anti-Markovnikov" hydrazones.
Cebrowski
Pamela H
PH
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, Ottawa, ON, Canada.
Roveda
Jean-Grégoire
JG
Moran
Joseph
J
Gorelsky
Serge I
SI
Beauchemin
André M
AM
D000480:Alkynes / Q000737:chemistry*; D000586:Amination; D006834:Hydrazines / Q000737:chemistry*; D013816:Thermodynamics
D000480:Alkynes; D006834:Hydrazines; C029424:hydrazine