title: Neonatal onset of hot water reflex seizures in monozygotic twins subsequently manifesting episodes of alternating hemiplegia.
abstract: We report on monozygotic twins with neonatal onset of daily reflex seizures triggered by hot water. Video record during the hot water bathing showed clinical signs consistent with a reflex seizure. The numbers of episodes were markedly reduced when the mother began bathing the children with reduced temperature bath water. At the age of 20 months, the twins developed episodes of paroxysmal disturbances including alternating hemiplegia. These two patients are the youngest reported cases of reflex hot water seizures, and the only reported cases in which reflex hot water seizures subsequently manifested episodes of alternating hemiplegia.
authors.affiliation: Department of Paediatrics, University of Catania, Italy.
authors.forename: Gemma
authors.initials: G
authors.lastname: Incorpora
authors.forename: Piero
authors.initials: P
authors.lastname: Pavone
authors.forename: Martino
authors.initials: M
authors.lastname: Ruggieri
authors.forename: Mariadonatella
authors.initials: M
authors.lastname: Cocuzza
authors.forename: Luigi
authors.initials: L
authors.lastname: Mazzone
authors.forename: Enrico
authors.initials: E
authors.lastname: Parano
authors.forename: Michael
authors.initials: M
authors.lastname: Privitera
mesh_terms: D003221:Confusion / Q000209:etiology / Q000523:psychology; D004569:Electroencephalography; D020195:Epilepsy, Reflex / Q000150:complications / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006429:Hemiplegia / Q000209:etiology* / Q000523:psychology; D006358:Hot Temperature; D006801:Humans; D007231:Infant, Newborn; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics; D014430:Twins, Monozygotic; D014867:Water
chemical_list: D014867:Water; C498531:ATP1A2 protein, human; D000254:Sodium-Potassium-Exchanging ATPase