Interpretation of pediatric endocrine laboratory tests: pitfalls in steroid hormone measurements and genotyping.
Accurate endocrine diagnosis depends on the integrity of laboratory determinations and appropriate interpretation of the test results in clinical context. This article will provide guidance to the pediatric endocrinologist and to the primary care provider in better understanding the selection and interpretation of laboratory tests.
Speiser
Phyllis W
PW
New York University School of Medicine, New York, NY 10016, USA. pspeiser@lij.edu
D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis; D002648:Child; D004700:Endocrine System Diseases / Q000175:diagnosis* / Q000235:genetics*; D005189:False Positive Reactions; D005260:Female; D005838:Genotype; D012739:Gonadal Steroid Hormones / Q000032:analysis* / Q000235:genetics*; D006801:Humans; D007118:Immunoassay; D007231:Infant, Newborn; D015997:Neonatal Screening; D010372:Pediatrics; D011629:Puberty, Precocious / Q000175:diagnosis; D012016:Reference Values; D012680:Sensitivity and Specificity; D013254:Steroid 17-alpha-Hydroxylase / Q000235:genetics; D013255:Steroid 21-Hydroxylase / Q000235:genetics; D013739:Testosterone / Q000097:blood
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D013255:Steroid 21-Hydroxylase; D013254:Steroid 17-alpha-Hydroxylase