title: Maturational tempo differences in relation to the timing of the onset of puberty in girls.
abstract: OBJECTIVE
  To determine maturational tempo differences related to the timing of pubertal onset in girls.
  
  
  METHODS
  We studied longitudinally 307 prepubertal Greek schoolgirls. Age at onset of puberty (B2), peak height velocity (PHV) and age at menarche were recorded. Age at onset of puberty quartiles were determined in order to define girls as early maturers (<9.2 years) and late maturers (>10.6 years). Due to dropout from the study, results for menarche are reported for 182 girls.
  
  
  RESULTS
  Median (1st-3rd quartile) time span from B2 to PHV was longer for early maturers than for average and late maturers, 1.6 (1.0-2.2) years, 1.1 (0.7-1.7) years and 0.9 (0.3-1.1) years, respectively, p < 0.001). There was no significant difference in PHV, in the time interval from PHV to menarche and in adult height (for 75 girls) with respect to whether girls matured early, average or late.
  
  
  CONCLUSIONS
  A compensatory delay in the maturational tempo in early-maturing girls and a catch-up mechanism in late-maturing girls was shown. The maturational differences manifest as differences in the time span from the onset of puberty to PHV. Early pubertal maturation in girls does not compromise adult height and is not always followed by early menarche.
authors.affiliation: Third Department of Pediatrics, University of Athens School of Medicine, Attikon University Hospital, Athens, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Pantsiotou
authors.forename: A
authors.initials: A
authors.lastname: Papadimitriou
authors.forename: K
authors.initials: K
authors.lastname: Douros
authors.forename: K
authors.initials: K
authors.lastname: Priftis
authors.forename: P
authors.initials: P
authors.lastname: Nicolaidou
authors.forename: A
authors.initials: A
authors.lastname: Fretzayas
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001827:Body Height; D002648:Child; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008572:Menarche / Q000502:physiology; D011627:Puberty / Q000502:physiology*