title: Small multidrug resistance plasmids in Actinobacillus porcitonsillarum.
abstract: The complete nucleotide sequences of six Actinobacillus porcitonsillarum plasmids pKMA202 (13.425-kb), pKMA1467 (11.115-kb), pKMA5 (9.549-kb), pIMD50 (8.751-kb), pKMA505 (8.632-kb) and pKMA757 (4.556-kb) and three Actinobacillus pleuropneumoniae plasmids pPSAS1522 (4.244-kb), pARD3079 (3.884-kb) and pKMA2425 (3.156-kb) were determined. All the plasmids contain the sulfonamide resistance gene sul2. One A. pleuropneumoniae plasmid and five A. porcitonsillarum plasmids also have the streptomycin resistance gene strA. Among these latter five A. porcitonsillarum plasmids, four also harbor the beta-lactam resistance gene bla(ROB-1). This study is the first report of multidrug resistance plasmids in the non-pathogenic A. porcitonsillarum.
authors.affiliation: Institute of Veterinary Bacteriology, University of Berne, Länggass-Strasse 122, Postfach, CH-3001 Bern, Switzerland.
authors.forename: Denise
authors.initials: D
authors.lastname: Matter
authors.forename: Alexandra
authors.initials: A
authors.lastname: Rossano
authors.forename: Sandra
authors.initials: S
authors.lastname: Sieber
authors.forename: Vincent
authors.initials: V
authors.lastname: Perreten
mesh_terms: D000188:Actinobacillus / Q000235:genetics* / Q000378:metabolism*; D001483:Base Sequence; D016000:Cluster Analysis; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D020161:Physical Chromosome Mapping; D010957:Plasmids / Q000235:genetics / Q000378:metabolism*