Silencing of the transcription factor KLF6 by siRNA leads to cell cycle arrest and sensitizes cells to apoptosis induced by DNA damage.
D'Astolfo
D S
DS
Gehrau
R C
RC
Bocco
J L
JL
Koritschoner
N P
NP
D000818:Animals; D017209:Apoptosis; D019556:COS Cells; D002453:Cell Cycle; D045744:Cell Line, Tumor; D002522:Chlorocebus aethiops; D004249:DNA Damage; D000075723:Kruppel-Like Factor 6; D051741:Kruppel-Like Transcription Factors / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000378:metabolism
C105465:KLF6 protein, human; D000075723:Kruppel-Like Factor 6; D051741:Kruppel-Like Transcription Factors; D011518:Proto-Oncogene Proteins; D034741:RNA, Small Interfering