title: Detecting faces in pure noise images: a functional MRI study on top-down perception.
abstract: To assess the nature of top-down perceptual processes without contamination from bottom-up input, this functional MRI study investigated face detection in pure noise images. Greater activation was revealed for face versus nonface responses in the fusiform face area, but not in the occipital face area. Across participants, positive correlations were found for the degree of greater face-detection activation between the fusiform face area and bilateral inferior frontal gyri, suggesting a top-down pathway generating perceptual expectations. In contrast, the medial frontal, parietal, supplementary motor, parahippocampal, and striatal areas produced negative correlations between degrees of greater face-detection activation and behavioral responses, suggesting a possible role for these areas in selecting and executing appropriate responses that are based on the top-down expectations.
authors.affiliation: Center for Human Development, University of California, San Diego, La Jolla, California, USA.
authors.forename: Hongchuan
authors.initials: H
authors.lastname: Zhang
authors.forename: Jiangang
authors.initials: J
authors.lastname: Liu
authors.forename: David E
authors.initials: DE
authors.lastname: Huber
authors.forename: Cory A
authors.initials: CA
authors.lastname: Rieth
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
authors.forename: Kang
authors.initials: K
authors.lastname: Lee
mesh_terms: D000328:Adult; D016477:Artifacts; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D003342:Corpus Striatum / Q000033:anatomy & histology / Q000502:physiology; D005145:Face; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008606:Mental Processes / Q000502:physiology; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology*; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology*