title: [Some notes on the history of the experimental surgery laboratory. Reflections on its relevance in education and surgical research].
abstract: The progress of medicine has largely been due to research, and for surgery, in particular, the experimental surgical laboratory has been considered fundamental to the surgeon's education. In this study, a general view of experimental surgery is given in animal models based on bioethical norms as well as to design, create and apply different surgical procedures before performing in humans. Experimental surgery also facilitates surgical teaching and promotes the surgeon's scientific reasoning. Methods. This is a retrospective and descriptive study. Data were collected from direct and indirect sources of available publications on the historical, bioethical and educational aspects of medicine, focusing on surgery. The important facts corresponding to the field of experimental surgery and applicable in Mexico were selected. Concepts of experimental surgical models and of the experimental surgery laboratory were described. Bioethical considerations are emphasized for care of experimental animals. Finally, this work focuses on the importance of surgical experimentation in current and future development of the surgical researcher. Conclusions. Experimentation with animal models in a surgical laboratory is essential for surgical teaching and promotes development of the scientific thought in the surgeon. It is necessary for surgical research and is fundamental for making progress in surgery, treatment and medicine as science.
authors.affiliation: Laboratorio de Biología de Células Madre y Virus, Departamento de Biología Molecular y Celular, Centro Médico Universitario de Leiden, Holland, UNAM. as_delagarza@hotmail.com
authors.forename: Anabel Sofía
authors.initials: AS
authors.lastname: de la Garza-Rodea
authors.forename: Luis
authors.initials: L
authors.lastname: Padilla-Sánchez
authors.forename: Javier
authors.initials: J
authors.lastname: de la Garza-Aguilar
authors.forename: Rolando
authors.initials: R
authors.lastname: Neri-Vela
mesh_terms: D000818:Animals; D001675:Bioethics / Q000266:history; D035843:Biomedical Research / Q000193:education / Q000941:ethics / Q000266:history*; D013502:General Surgery / Q000193:education / Q000266:history*; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049690:History, Ancient; D049691:History, Medieval; D023421:Models, Animal