title: [Photodynamic therapy in severe chronic central serous chorioretinopaty].
abstract: OBJECTIVE
  To determine the efficacy of Photodynamic Therapy (PDT) in chronic Central Serous Chorioretinopathy (CSC).
  
  
  METHODS
  Patients diagnosed with chronic CSC, with clinical evidence of activity and treated with Photodynamic Therapy, are included in this report. All were assessed by a complete ophthalmological examination, including assessment of the best corrected visual acuity (BCVA) using an ETDRS chart, fluorescein and indocyanine angiography and optical coherence tomography (OCT). The main objective of the study was to determine the mean visual acuity change.
  
  
  RESULTS
  11 eyes of 11 patients were included in the study, which had a mean follow-up period of 11 months. The mean BCVA increased from 20/76 to 20/64. 35% of eyes improved their BCVA by 2 lines or more, 45% remained stable and 18% lost 2 lines or more. Choroidal hyperpermeability was reduced in every case. Neurosensorial retinal detachment decreased in 80% of cases. Only one eye received a second PDT treatment due to choroidal neovascularization. An increase of atrophy over the Retinal Pigment Epithelium (RPE) was observed in another patient.
  
  
  CONCLUSIONS
  PDT can reduce the clinical signs of activity, such as choroidal hyperpermeability or neurosensorial retinal detachment, in patients affected by chronic CSC. However, the increase in visual acuity is variable, probably due to the extent of RPE damage.
authors.affiliation: Sección de Retina, Servicio de Oftalmología, Hospital Clínico San Carlos, Madrid, España. rechejuan@yahoo.es
authors.forename: J
authors.initials: J
authors.lastname: Reche-Frutos
authors.forename: C
authors.initials: C
authors.lastname: Calvo-González
authors.forename: J
authors.initials: J
authors.lastname: Donate-López
authors.forename: F
authors.initials: F
authors.lastname: Sáenz-Francés-San-Baldomero
authors.forename: I
authors.initials: I
authors.lastname: Cerván-López
authors.forename: J
authors.initials: J
authors.lastname: García-Feijoó
authors.forename: J
authors.initials: J
authors.lastname: García-Sánchez
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000150:complications / Q000188:drug therapy*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D012164:Retinal Diseases / Q000150:complications / Q000188:drug therapy*; D012720:Severity of Illness Index