[Tumor makrers in cervical cancer].
IMeasurement of tumor markers level in human body fluids, mainly in serum may be useful for diagnosis, therapy monitoring and early recurrence detection. SCC-Ag, Cyfra 21-1, CEA, CA 125 and TPS are of a clinical value in uterine cervical cancer despite their diverse significance. Other biological markers that could be measured in serum as well as in tumor tissue are cytokines: VEGF, IL-6, IL-8, IL-4, IL-10, leptin, stromal drive factor (SDF- 1), although assessment of their importance needs further examination. Elevation of uterine cervical cancer hypoxia markers such as HIF 1a, CA 9, GLUT-1 is combined with poorer clinical outcome prognosis.
Markowska
Janina
J
Katedra Onkologii Uniwersytetu Medycznego im. K. Marcinkowskiego w Poznaniu.
D000951:Antigens, Neoplasm / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D001774:Blood Chemical Analysis / Q000379:methods; D018394:CA-125 Antigen / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000097:blood; D005260:Female; D006801:Humans; D016753:Interleukin-10 / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D016209:Interleukin-8 / Q000097:blood; D053539:Keratin-19; D007633:Keratins / Q000097:blood; D009367:Neoplasm Staging; D011379:Prognosis; D015843:Serpins / Q000097:blood; D002583:Uterine Cervical Neoplasms / Q000097:blood*; D042461:Vascular Endothelial Growth Factor A / Q000097:blood
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D002272:Carcinoembryonic Antigen; D015850:Interleukin-6; D016209:Interleukin-8; D053539:Keratin-19; D015843:Serpins; D042461:Vascular Endothelial Growth Factor A; C102012:antigen CYFRA21.1; C051072:squamous cell carcinoma-related antigen; D016753:Interleukin-10; D015847:Interleukin-4; D007633:Keratins