[Blood serum osteocalcin and beta-crosslaps concentrations in patients after renal transplantation].
In 16 patients (7 males, 9 females), aged 47.2 +/- 15.9 years, blood serum concentrations of osteocalcin, beta-crosslaps, parathormone, calcium, phosphate, creatinine and urea were determined before renal transplantation and 3 and 6 months following the procedure. Three as well as six months following renal transplantation significant decrease in blood serum concentration of osteocalcin and beta-crosslaps are found. A significant positive correlation between osteocalcin and beta-crosslaps concentration was found in each investigated period. Six-months observation revealed only partial correction of bone metabolism following renal transplantation.
Zbróg
Zbigniew
Z
Oddział Nefrologii WSS im. M. Kopernika, Łódź. zbigniewzbrog@interia.pl
Tomaszek
Małgorzata
M
Szuflet
Adam
A
Pierzchalska-Mudyna
Teresa
T
Rybińska
Agnieszka
A
Skrzypek
Agnieszka
A
Matych
Józef
J
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001862:Bone Resorption / Q000097:blood / Q000209:etiology; D001842:Bone and Bones / Q000378:metabolism; D003094:Collagen / Q000097:blood*; D003404:Creatinine / Q000097:blood; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood*; D010012:Osteogenesis / Q000187:drug effects; D010446:Peptide Fragments / Q000097:blood*; D016559:Tacrolimus / Q000627:therapeutic use
D015415:Biomarkers; D007166:Immunosuppressive Agents; D010446:Peptide Fragments; C110762:glutamyl-lysyl-alanyl-histidyl-aspartyl-glycyl-glycyl-arginine; D015675:Osteocalcin; D016572:Cyclosporine; D003094:Collagen; D003404:Creatinine; D016559:Tacrolimus