title: EndoCinch treatment for gastro-oesophageal reflux disease.
abstract: Gastro-oesophageal reflux disease (GORD) is a common disorder which significantly impairs the quality of life. Recently an EndoCinch system has been described, with an approach to the treatment of GORD that would obviate the need for long-term proton pump inhibitors and the cost and potential risk of laparoscopic Nissen fundoplication. We set outto evaluate the status of this new technique for the management of GORD. We review the literatures (publications and abstracts) regarding safety, efficacy, and durability of this new antireflux procedure. On the whole, this new antireflux technique produced significant improvement in GORD symptomatology and quality of life and reduced the use of antireflux medication. However, it failed to normalize acid reflux, long-term durability data are lacking, and some serious side effects have been reported. In conclusion, EndoCinch has the potential to treat patients with this common ailment. However, further studies are necessary to determine what modifications to this antireflux technique are required in order to produce the maximum clinical benefit.
authors.affiliation: Department of Gastroenterology, West Cumberland Hospital, Whitehaven, UK. zahid@zmahmood2.wanadoo.co.uk
authors.forename: Z
authors.initials: Z
authors.lastname: Mahmood
authors.forename: Y S
authors.initials: YS
authors.lastname: Ang
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects / Q000266:history / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D049673:History, 20th Century; D006801:Humans; D018579:Patient Selection