Vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa.
Among African immigrants in Melbourne, Victoria, Australia, we demonstrated lower geometric mean vitamin D levels in immigrants with latent tuberculosis infection than in those with no Mycobacterium tuberculosis infection (P=.007); such levels were also lower in immigrants with tuberculosis or past tuberculosis than in those with latent tuberculosis infection (P=.001). Higher vitamin D levels were associated with lower probability of any M. tuberculosis infection (P=.001) and lower probability of tuberculosis or past tuberculosis (compared with latent tuberculosis infection; P=.001).
Gibney
Katherine B
KB
Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, Victoria, Australia. katherinegibney@hotmail.com
MacGregor
Lachlan
L
Leder
Karin
K
Torresi
Joseph
J
Marshall
Caroline
C
Ebeling
Peter R
PR
Biggs
Beverley-Ann
BA
D000293:Adolescent; D000328:Adult; D017954:Africa South of the Sahara / Q000208:ethnology; D000368:Aged; D001315:Australia / Q000453:epidemiology; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D012189:Retrospective Studies; D012307:Risk Factors; D014376:Tuberculosis / Q000453:epidemiology / Q000378:metabolism* / Q000382:microbiology; D014808:Vitamin D Deficiency / Q000453:epidemiology / Q000382:microbiology*