title: Death related to pleural and pericardial effusions following chemoradiotherapy in a patient with advanced cancers of the esophagus and stomach.
abstract: Chemoradiotherapy improves therapeutic outcome in many different types of cancer. However, there is concern about the occurrence of delayed complications, as patients are surviving longer. Because patients with esophageal cancer receive a wide range of irradiation field to the mediastinum and the heart, they may have delayed complications of heart and lung functions as previously reported in Hodgkin's disease. We presented a case of death related to uncontrollable pleural and pericardial effusions in a patient with advanced cancers of the esophagus and stomach who achieved a complete remission following chemoradiotherapy and salvage gastric resection, focusing on detailed pathophysiological conditions related to concurrent chemoradiotherapy.
authors.affiliation: Department of Radiology, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. shige@rad.med.keio.ac.jp
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Shigematsu
authors.forename: Naoto
authors.initials: N
authors.lastname: Kitamura
authors.forename: Yoshirou
authors.initials: Y
authors.lastname: Saikawa
authors.forename: Eiji
authors.initials: E
authors.lastname: Ikeda
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Fukada
authors.forename: Etsuo
authors.initials: E
authors.lastname: Kunieda
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Keiichi
authors.initials: K
authors.lastname: Fukuda
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Okada
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kubo
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D004938:Esophageal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010490:Pericardial Effusion / Q000150:complications*; D010996:Pleural Effusion / Q000150:complications*; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D017211:Treatment Failure