Vincristine-induced peripheral neuropathy and urinary bladder paralysis in a child with rhabdomyosarcoma.
Vincristine commonly induces peripheral neuropathy but rarely causes voiding dysfunction. In this report, we describe a case of neurogenic bladder and peripheral neuropathy caused by the neurotoxic effect of vincristine and documented by urodynamic testing and electromyography. Neurologic evaluation aided in monitoring and understanding this problem.
Citak
Elvan Caglar
EC
Department of Pediatric Oncology, Gazi University Faculty of Medicine, Besevler, Ankara, Turkey. caglarcitak@yahoo.com
Oguz
Aynur
A
Karadeniz
Ceyda
C
Karaoglan
Belgin
B
Tan
Mustafa Ozgur
MO
Okur
Visal
V
Cansu
Ali
A
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D003609:Dactinomycin / Q000008:administration & dosage / Q000009:adverse effects; D004576:Electromyography; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D010243:Paralysis / Q000139:chemically induced*; D012208:Rhabdomyosarcoma / Q000150:complications* / Q000188:drug therapy; D001750:Urinary Bladder, Neurogenic / Q000139:chemically induced*; D014563:Urodynamics; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects*
D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide