title: Raloxifene effects on thyroid gland morphology in ovariectomized rats.
abstract: We aimed to analyze the effects of raloxifene and estrogen on thyroid gland morphology of ovariectomized rats. Raloxifene treatment led to effects similar to those of estrogen on thyroid glands from ovariectomized rats, so that both were able to normalize the changes detected after ovariectomy.
authors.affiliation: Laboratório de Fisiologia Endócrina, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil. lfbita@gmail.com
authors.forename: Luiz Felipe Bittencourt
authors.initials: LF
authors.lastname: de Araujo
authors.forename: Renata
authors.initials: R
authors.lastname: Grozovsky
authors.forename: Mônica
authors.initials: M
authors.lastname: de Campos Pinheiro
authors.forename: Jorge José
authors.initials: JJ
authors.lastname: de Carvalho
authors.forename: Mário
authors.initials: M
authors.lastname: Vaisman
authors.forename: Denise P
authors.initials: DP
authors.lastname: Carvalho
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D009929:Organ Size / Q000187:drug effects; D010052:Ovariectomy; D020849:Raloxifene Hydrochloride / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D020845:Selective Estrogen Receptor Modulators / Q000008:administration & dosage; D013961:Thyroid Gland / Q000033:anatomy & histology* / Q000187:drug effects*
chemical_list: D004967:Estrogens; D020845:Selective Estrogen Receptor Modulators; D020849:Raloxifene Hydrochloride