Viral load as predictor of Crimean-Congo hemorrhagic fever outcome.
We used quantitative real-time reverse transcription-PCR to measure viral load in serum from 24 patients in Kosovo who had acute Crimean-Congo hemorrhagic fever. Viral load correlated with clinical disease and antibodies and could be used as a predictor of disease outcome.
Duh
Darja
D
Institute of Microbiology and Immunology, Ljubljana, Slovenia.
Saksida
Ana
A
Petrovec
Miroslav
M
Ahmeti
Salih
S
Dedushaj
Iusuf
I
Panning
Marcus
M
Drosten
Christian
C
Avsic-Zupanc
Tatjana
T
D004797:Enzyme-Linked Immunosorbent Assay; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000302:isolation & purification*; D006479:Hemorrhagic Fever, Crimean / Q000276:immunology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019562:Viral Load; D015022:Yugoslavia
D007074:Immunoglobulin G; D007075:Immunoglobulin M