title: [Heparin-induced thrombocytopenia: a case of persistent thrombocytopenia].
abstract: Heparin-induced thrombocytopenia is rare. It should be considered if there is a reduction of at least 40% in the number of platelets and/or a level<100,000/mm3 in any patients who have received heparin in the previous 100 days. On stopping heparin, the rise in platelets is classically rapid, and normal levels are usually obtained in under 7 days. We report a case of heparin-induced thrombocytopenia, which was marked by a severe thrombocytopenia that only returned to normal 19 days after stopping heparin, in a patient treated initially with non-fractionated heparin for a pulmonary embolism secondary to an extensive deep venous thrombosis of the right lower limb.
authors.affiliation: CHRU de Lille Hôpital cardiologique Calmette.
authors.forename: M
authors.initials: M
authors.lastname: Jourdain
authors.forename: P-V
authors.initials: PV
authors.lastname: Ennezat
authors.forename: J
authors.initials: J
authors.lastname: Darchis
authors.forename: J-M
authors.initials: JM
authors.lastname: Aubert
authors.forename: J-J
authors.initials: JJ
authors.lastname: Bauchart
authors.forename: J-L
authors.initials: JL
authors.lastname: Auffray
authors.forename: P
authors.initials: P
authors.lastname: Asseman
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D011655:Pulmonary Embolism / Q000188:drug therapy; D013921:Thrombocytopenia / Q000139:chemically induced*; D020246:Venous Thrombosis / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D006493:Heparin