title: [Long latency auditory evoked potentials in adults with HIV/Aids].
abstract: BACKGROUND
  Long Latency Auditory Evoked Potentials.
  
  
  OBJECTIVE
  to characterize the Long Latency Auditory Evoked Potentials (LLAEP) in individuals with HIV/AIDS in comparison to a control group.
  
  
  METHODS
  the research sample was composed by 21 individuals with HIV/AIDS - research group (14 male and 7 female), with ages ranging from 31 to 48 years, and 21 healthy individuals - control group (5 male and 16 female), with ages ranging from 19 to 36 years. The latency and amplitude values of the P300 wave were analyzed; latency of N1 and P2 waves, and amplitude N1-P2. The electrodes were placed on the following positions: A1, A2, Cz and Fpz.
  
  
  RESULTS
  the T-student test was used to analyze the results and the adopted significance level was of 5%. In the analyzes of P300 it was observed that the group with HIV/AIDS presented greater latency values (p-value = 0,010) and lower amplitude values (p-value = 0,021) when compared to the control group. The analysis of the N1-P2 complex revealed that the research group presented higher latency values for both, N1 wave (p-value = 0,035) and P2 wave, however for this last one, there was no significant statistical difference when compared to the control group. Concerning the amplitude analysis of the N1-P2 complex, it was verified that the control group presented significantly higher values when compared to the research group.
  
  
  CONCLUSIONS
  the findings of this study indicates that individuals with HIV/AIDS present alterations in the Long Latency Auditory Evoked Potentials (higher latencies and lower amplitudes of N1, P2 and P300 waves), suggesting a disorder in the cortical regions of the auditory pathway, and therefore stressing the importance of such tests in the evaluation of these individuals.
authors.affiliation: Faculdade de Medicina, Universidade de São Paulo, São Paulo. aline.covo@uol.com.br
authors.forename: Aline Covo da
authors.initials: AC
authors.lastname: Silva
authors.forename: Fernanda Rodrigues
authors.initials: FR
authors.lastname: Pinto
authors.forename: Carla Gentile
authors.initials: CG
authors.lastname: Matas
mesh_terms: D000161:Acoustic Stimulation; D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology; D000328:Adult; D001304:Auditory Diseases, Central / Q000150:complications / Q000175:diagnosis*; D016022:Case-Control Studies; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time