title: Hypertension due to co-existing paraganglioma and unilateral adrenal cortical hyperplasia.
abstract: A rare case of combined unilateral adrenal hyperplasia and paraganglioma is reported. A 27-year-old woman presented with hypertension, palpitation, dizziness, and headache for about 3 months. Elevated plasma aldosterone with low renin and a high level of urine vanillylmandelic acid (VMA) were found. Computed tomography showed a microadenoma of the left adrenal gland and a well demarcated left retroperitoneal para-aortic mass. Adrenal vein sampling for aldosterone and renin levels suggested left adrenal lesion. Surgical removal of the left adrenal gland and para-aortic mass was performed. Pathologic examination of the resected left adrenal gland showed adrenal cortical hyperplasia and the left retroperitoneal para-aortic mass showed a paraganglioma. Postoperatively, blood pressure, plasma renin, aldosterone and urine VMA all returned to within normal ranges. The possible relationship of these two diseases is discussed.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
authors.forename: Kuo-Hsuan
authors.initials: KH
authors.lastname: Chiang
authors.forename: Jer-Young
authors.initials: JY
authors.lastname: Liou
authors.forename: Kou-Gi
authors.initials: KG
authors.lastname: Shyu
authors.forename: Chung-Hsin
authors.initials: CH
authors.lastname: Yeh
authors.forename: Chin-Chu
authors.initials: CC
authors.lastname: Wu
authors.forename: Tong-Jong
authors.initials: TJ
authors.lastname: Chen
authors.forename: Huey-Ming
authors.initials: HM
authors.lastname: Lo
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications*; D006973:Hypertension / Q000209:etiology*; D010236:Paraganglioma, Extra-Adrenal / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010673:Pheochromocytoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012186:Retroperitoneal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed