A metal-complex-tolerant CuAAC 'click' protocol exemplified through the preparation of homo- and mixed-metal-coordinated [2]rotaxanes.
A series of mono- and bis-metallated [2]rotaxanes has been prepared using a CuAAC 'click' protocol that is compatible with metal-coordinated building blocks and ligands; the methodology provides a general means for appending a metal ion or complex to an organic scaffold via Cu(I)-catalysed 'click' chemistry, even when the molecule contains redox-active or kinetically labile metals or vacant ligand sites.
González Cabrera
Diego
D
School of Chemistry, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh, UK.
Koivisto
Bryan D
BD
Leigh
David A
DA
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D012015:Reference Standards; D043862:Rotaxanes / Q000737:chemistry*; D013237:Stereoisomerism
D008024:Ligands; D009942:Organometallic Compounds; D043862:Rotaxanes; D003300:Copper