Aminobromination of olefins with TsNH(2) and NBS as the nitrogen and bromine sources mediated by hypervalent iodine in a ball mill.
A series of olefins including alpha,beta-unsaturated ketones, cinnamates, cinnamides and styrenes have been aminobrominated with good yields and excellent diastereoselectivities under mechanical milling conditions, using TsNH(2) and NBS as the nitrogen and bromine sources, promoted by (diacetoxyiodo)benzene.
Wu
Xue-Liang
XL
Hefei National Laboratory for Physical Sciences, Hefei, Anhui, People's Republic of China.
Xia
Jing-Jing
JJ
Wang
Guan-Wu
GW