title: [Clinical application of beta-blockers with particular reference to hypertension].
abstract: Beta-blockers are effective in reducing the blood pressure of many patients with systemic hypertension. They differ in terms of the presence or absence of partial agonistic activity, membrane-stabilizing activity, beta-1 selectivity, alfa-blocking properties and relative potency and duration of action. All beta-blockers appear to have blood pressure lowering effects. The choice of beta-blocker in individual patient is determined by the pharmacodynamic and pharmacokinetic differences between the drugs in conjunction with the patient's other medical conditions. This review discusses the practical use of beta-blockers and provides rational suggestions for these drugs to be used in various clinical situations.
authors.forename: M
authors.initials: M
authors.lastname: Kocijancić
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*
chemical_list: D000319:Adrenergic beta-Antagonists