title: Unusual coexistence of bilateral keratoconus and optic disc pit: a case report.
abstract: OBJECTIVE
  To report the unknown coexistence of bilateral optic disc pit and keratoconus.
  
  
  METHODS
  A 23-year-old man with bilateral keratoconus underwent complete ophthalmology screening, with an unexpected detection of undiagnosed optic disc pit in both eyes. Computerized corneal topography (CT), Orbscan, corneal pachometry, endothelial microscopy, and optical coherence tomography (OCT) examination were performed.
  
  
  RESULTS
  The corneal CT showed a keratoconus pattern in both eyes, evolved in the right eye with a minimum corneal pachometry of 336 micronm in the right eye and 405 micronm in the left eye. Mean endothelial cell density was 1937 cells/mm2 in the right eye and 1912 cells/mm2 in the left eye. The OCT scans showed the presence of the disc pit in both eyes with a normal macular thickness and profile in the right eye, and in the left eye an augmented retinal thickness in the nasal macular zone due to retinal oedema and schisis, with an initial detachment of the neuroepithelium in the parapapillary area starting from the optic pit.
  
  
  CONCLUSIONS
  This is the first clinical report of bilateral optic disc pit and keratoconus. Further investigations will be necessary to assess if there is a possible pathogenetic correlation between these two ocular pathologies or if this is an unusual coexistence of separate entities.
authors.affiliation: Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Roma, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Fasciani
authors.forename: L
authors.initials: L
authors.lastname: Mosca
authors.forename: M L
authors.initials: ML
authors.lastname: Giannico
authors.forename: E F
authors.initials: EF
authors.lastname: Legrottaglie
authors.forename: E
authors.initials: E
authors.lastname: Balestrazzi
mesh_terms: D000328:Adult; D019781:Corneal Topography; D005124:Eye Abnormalities / Q000150:complications* / Q000175:diagnosis; D007839:Functional Laterality; D006801:Humans; D007640:Keratoconus / Q000150:complications* / Q000175:diagnosis; D008297:Male; D009898:Optic Disk / Q000002:abnormalities*; D041623:Tomography, Optical Coherence