title: Assessment of healing kinetics through true color image processing.
abstract: A quantitative method of skin healing assessment using true color image processing is presented. The method was developed during a clinical trial using healthy volunteers, the goal of which was to study a drug for accelerating healing. Photographic images of the skin were sequentially acquired between day 1 and day 12 after pure painless epidermal wounds. The images were digitized in controlled conditions using a color video camera connected to a computer system. A color threshold based segmentation was developed to provide an operator-independent delineation of the wound. Two healing indexes were built measuring, the wound area and the wound color. The method was implemented in a software system allowing a fully automated determination of the healing indexes. The method provides a new quantitative global assessment of healing kinetics. It is noninvasive and well suited for multicentric clinical trials.
authors.affiliation: ECLIMED, Hoptial Cochin, Paris.
authors.forename: M
authors.initials: M
authors.lastname: Herbin
authors.forename: F X
authors.initials: FX
authors.lastname: Bon
authors.forename: A
authors.initials: A
authors.lastname: Venot
authors.forename: F
authors.initials: F
authors.lastname: Jeanlouis
authors.forename: M L
authors.initials: ML
authors.lastname: Dubertret
authors.forename: L
authors.initials: L
authors.lastname: Dubertret
authors.forename: G
authors.initials: G
authors.lastname: Strauch