title: Mitral valve replacement and tricuspid valve repair in a patient with sickle cell disease.
abstract: Sickle cell disease is a rare entity for the European cardiac surgeon to encounter. Low oxygen tension, acidosis and hypothermia may induce sickling and pose a great risk in this population during open heart surgery. We report the management of a 57-year-old Greek woman with homozygous sickle cell disease and rheumatoid arthritis, who underwent preoperative partial exchange transfusion and subsequent mitral valve replacement and tricuspid valve repair at normothermia.
authors.affiliation: Department of Cardiac Surgery, Athens Medical Center, Athens, Greece. lazopoulosg@ath.forthnet.gr
authors.forename: G
authors.initials: G
authors.lastname: Lazopoulos
authors.forename: M M
authors.initials: MM
authors.lastname: Kantartzis
authors.forename: M
authors.initials: M
authors.lastname: Kantartzis
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D001172:Arthritis, Rheumatoid / Q000150:complications; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000601:surgery*; D014262:Tricuspid Valve Insufficiency / Q000601:surgery*