Neurogenesis and depression: breakthrough or blind alley?
Pieces of evidence are emerging in support of the startling idea that the birth of new neurones in the adult brain in some way underlies major depression. Although there are intriguing parallels between factors that regulate neurogenesis and those predicting depression or its recovery, at this point, we should remain sceptical but allow cautious hope that more effective therapies may be suggested.
Herbert
Joe
J
Department of Physiology, Development & Neuroscience, Cambridge Centre for Brain Repair, University of Cambridge, UK.
D000928:Antidepressive Agents / Q000494:pharmacology; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology*; D003865:Major Depressive Disorder / Q000209:etiology*; D006801:Humans; D006854:Hydrocortisone / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*
D000928:Antidepressive Agents; D006854:Hydrocortisone