[Characteristics of respiratory disorders in acute leukemia].
OBJECTIVE
To characterize respiratory disorders and microflora in patients with acute leukemia (AL).


METHODS
Examination of the respiratory organs was made in 72 patients admitted to Hematological Center of Armenia (HCA) in 2005. Also, a retrospective analysis of the records on 126 AL patients treated in HCA during 2002-2004 was made.


RESULTS
Lesions of the lungs and mediastinum were detected in 61 (30.8%) patients. Infectious complications were found in 45 (73.8%) patients, of them 30 (48.3%) patients had pneumonia. Interstitial pneumonia, chronic bronchitis, exudative pleurisy, pulmonary tuberculosis, fungal affection of the lungs were diagnosed in 5, 5, 10, 6 and 4 patients, respectively. Bacterial flora caused pneumonia in 30 patients. Gram positive and negative flora was found in 9 out of 24 cases. In 5 patients the flora was mixed. The policy of the antibacterial treatment was proposed. Roentgenological semiography in different pulmonary affections has characteristic features. Leukemoid infiltration of the lungs occurred in 6 AL patients. Blast pleurisy was found in 6 patients.


CONCLUSIONS
The policy of correction of microbial spectrum in AL patients using optimal schemes of antibacterial therapy is proposed.
Dagbashian
S S
SS
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008875:Middle Aged; D011379:Prognosis; D013902:Radiography, Thoracic; D012141:Respiratory Tract Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012189:Retrospective Studies; D013183:Sputum / Q000382:microbiology
D000900:Anti-Bacterial Agents