title: Should excised keloid scars be sent for routine histologic analysis?
abstract: BACKGROUND
  Keloid scarring is a clinical diagnosis, usually preceded by a history of localized trauma. Significant variation exists as to whether excised specimens are sent for routine histologic analysis. We aimed to review the histology of all clinically diagnosed keloids at our unit.
  
  
  METHODS
  All keloids diagnosed clinically and excised were identified between April 1995 and April 2006. The subsequent histology results were analyzed.
  
  
  RESULTS
  Five hundred sixty-eight specimens were sent for pathologic investigation over an 11-year period. Four hundred fifty-eight (81%) were reported as "keloid," 60 (11%) as "acne keloidalis," 35 (6%) as "hypertrophic scar," and 14 (2%) as "normal scar." There were no reported malignancies or dysplasias.
  
  
  CONCLUSIONS
  These histology results suggest that, given a good clinical suspicion of keloid, it may be unnecessary to send specimens at excision for routine histology.
authors.affiliation: Department of Plastic Surgery, St George's Hospital, London, England. nadimgulam@gmail.com
authors.forename: Nadim
authors.initials: N
authors.lastname: Gulamhuseinwala
authors.forename: Simon
authors.initials: S
authors.lastname: Mackey
authors.forename: Peter
authors.initials: P
authors.lastname: Meagher
authors.forename: Barry
authors.initials: B
authors.lastname: Powell
mesh_terms: D003955:Diagnostic Tests, Routine; D006801:Humans; D007627:Keloid / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery