title: Disseminated juvenile xanthogranulomatosis in a newborn resulting in liver transplantation.
abstract: Juvenile xanthogranuloma is a histiocytic tumor that usually appears at birth or during the first year of life. Although most patients have solitary lesions, some have multiple cutaneous lesions, associated visceral lesions, or both. Although juvenile xanthogranulomas are usually confined to the skin; visceral involvement does occur in a small subset of patients and can be life threatening. We describe a newborn girl initially described as a "blueberry muffin baby" with multiple juvenile xanthogranulomas of the skin and liver that were complicated by progressive cholestasis and portal hypertension necessitating a liver transplantation.
authors.affiliation: Island Dermatology, Long Beach, New York, USA.
authors.forename: Adrienne M
authors.initials: AM
authors.lastname: Haughton
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Horii
authors.forename: Lei
authors.initials: L
authors.lastname: Shao
authors.forename: James
authors.initials: J
authors.lastname: Daniel
authors.forename: Amy Jo
authors.initials: AJ
authors.lastname: Nopper
mesh_terms: D002675:Child, Preschool; D002779:Cholestasis / Q000209:etiology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000601:surgery*; D008103:Liver Cirrhosis / Q000209:etiology / Q000601:surgery; D016031:Liver Transplantation; D014972:Xanthogranuloma, Juvenile / Q000150:complications / Q000601:surgery*