[A case of complete remission(CR)persisting from UFT-E in an old patient with liver metastasis of gastric cancer].
A 82-year-old woman with gastric cancer underwent distal gastrectomy with level 2 lymph node dissection(M, Less, 2.2 x 2.0 cm, type 1, fH0, fP0, fM0, fT2, fN2(+), por 1, med, INF beta, ly2, v2, fPM(-), fDM(-), fStage IIIa). At first, adjuvant chemotherapy was not given because of her advanced age, but CEA increased to 43.2 ng/mL and a CT scan showed multiple liver metastasis. After we began oral chemotherapy with UFT-E 300 mg/day, the CEA level normalized and a CT scan revealed the liver metastasis had disappeared within about 9 months. There were no side effects for a course, and she has been free from any sign of recurrence. This was a very rare case in which single administration of UFT-E caused complete remission. Even an old patient should be treated aggressively because this treatment is relatively safe.
Kazunori Ikenaga
Shojiro
S
Dept. of Surgery, Public Shichinohe Hospital.
Hirama
Kimiaki
K
Matsumoto
Rikuro
R
Maruyama
Masateru
M
Aoki
Kazunori
K
Sakamoto
Yoshiyuki
Y
Sakuraba
Hiroyasu
H
Oguro
Hiroshi
H
D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D005641:Tegafur / Q000627:therapeutic use; D015898:Tomography Scanners, X-Ray Computed; D014498:Uracil / Q000627:therapeutic use
D005641:Tegafur; D014498:Uracil