Brain magnetic resonance imaging findings in acute relapses of neuromyelitis optica spectrum disorders.
We studied cranial magnetic resonance imaging (MRI) lesions in three women with acute attacks of recurrent longitudinally extensive transverse myelitis (r-LETM), recurrent-optic neuritis (r-ON) and r-LETM-CNS. Neuromyelitis Optica -immunoglobulin (IgG) antibody was positive in all cases. Brain MRI (1.5 Tesla) was performed according to protocol from consortium MS centre. We described the cranial lesions in brain MRI of acute relapses. These lesions were different from MS, most had an asymptomatic course which disappeared with time, protocol from consortium of MS centre criteria for brain MRI and seropositivity of NMO-IgG are useful tools for differentiate acute lesions of NMO/MS.
Cabrera-Gómez
Ja
J
International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba. cabrera.gomez@infomed.sld.cu
Saiz-Hinarejos
A
A
Graus
F
F
González-Quevedo
A
A
Rodríguez-Rojas
R
R
Quevedo-Sotolongo
L
L
Real-González
Y
Y
Grass-Fernández
D
D
Cristófol-Corominas
M
M
Rodríguez-Cordero
Ml
M
Robinson-Agramonte
Ma
M
Infante-Velázquez
E
E
Cabrera-Núñez
A
A
Ugarte-Sánchez
C
C
Jordán-González
J
J
González de la Nuez
Je
J
García-Lahera
J
J
Tellez
R
R
Baez-Martín
M
M
Romero-García
K
K
D000208:Acute Disease; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008279:Magnetic Resonance Imaging; D009471:Neuromyelitis Optica / Q000276:immunology / Q000473:pathology*; D012008:Recurrence
D001323:Autoantibodies; D007074:Immunoglobulin G