title: [Osteomyelitis of the jaw in breast cancer patients receiving bisphosphonate therapy].
abstract: Osteonecrosis of the jaw is a severe new complication in cancer patients with bone metastases receiving bisphosphonate. Currently, there is no effective treatment for bisphosphonate-related osteonecrosis of the jaw, and the pathogenesis of this complication has not been completely elucidated. It has been shown that a potential risk factor for the complication is dentoalveolar trauma including extraction of teeth during bisphosphonate therapy. Attention should be paid to dental care in patients prior to the initiation of bisphosphonate therapy, and extraction of teeth during bisphosphonate therapy should be avoided to prevent this complication. Therefore, the communication between general physicians prescribing bisphosphonate and dentists is important.
authors.affiliation: Dept. of Oral Surgery, Sapporo Medical University School of Medicine.
authors.forename: Kei
authors.initials: K
authors.lastname: Tomihara
authors.forename: Itaru
authors.initials: I
authors.lastname: Nagai
authors.forename: Akira
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Miyazaki
authors.forename: Hironari
authors.initials: H
authors.lastname: Dehari
authors.forename: Masato
authors.initials: M
authors.lastname: Abe
authors.forename: Kenji
authors.initials: K
authors.lastname: Nakamori
authors.forename: Kiyoto
authors.initials: K
authors.lastname: Komai
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Nakai
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Hiratsuka
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy*; D004164:Diphosphonates / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology*; D010019:Osteomyelitis / Q000139:chemically induced* / Q000473:pathology*; D011859:Radiography
chemical_list: D004164:Diphosphonates