Synthetic approaches to the 2006 new drugs.
New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 16 NCEs marketed in 2006.
Liu
Kevin K-C
KK
Pfizer Inc, La Jolla, CA 92037, USA. Kevin.k.liu@pfizer.com
Sakya
Subas M
SM
Li
Jin
J
D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000145:classification
D004364:Pharmaceutical Preparations