title: [Squamous cell carcinoma of the anal canal in the elderly showing complete response following radiotherapy--a case report].
abstract: We reported an elderly case of squamous cell carcinoma of the anal canal which showed complete response following radiotherapy alone. An 86-year-old man complaining of anal bleeding and pain was admitted. Colonoscopy showed a type 1 tumor just above the dentate line. Biopsy revealed squamous cell carcinoma. Serum SCC Level before treatment was elevated (8.4 ng/mL). Magnetic resonance imaging did not show any metastatic lesions. Since the patient and his family members refused a surgical intervension and chemotherapy, he received an external radiotherapy (total dose: 60 Gy) to the pelvic space and showed complete response after radiotherapy. He is alive without evidence of recurrence about three years after the radiation, although serum SCC is slightly elevated.
authors.affiliation: Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Amano
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakada
authors.forename: Norimichi
authors.initials: N
authors.lastname: Okada
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Miyazaki
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Gonda
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
authors.forename: Takeo
authors.initials: T
authors.lastname: Takahashi
mesh_terms: D000369:Aged, 80 and over; D001005:Anus Neoplasms / Q000097:blood / Q000473:pathology* / Q000532:radiotherapy*; D014408:Biomarkers, Tumor / Q000097:blood; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000473:pathology* / Q000532:radiotherapy*; D003113:Colonoscopy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor