title: Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.
abstract: The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.
authors.affiliation: Instituto Universitario de Bio-Orgánica Antonio González, La Laguna, Tenerife, Spain.
authors.forename: Jesús G
authors.initials: JG
authors.lastname: Díaz
authors.forename: Armando J
authors.initials: AJ
authors.lastname: Carmona
authors.forename: Fernando
authors.initials: F
authors.lastname: Torres
authors.forename: José
authors.initials: J
authors.lastname: Quintana
authors.forename: Francisco
authors.initials: F
authors.lastname: Estévez
authors.forename: Werner
authors.initials: W
authors.lastname: Herz
mesh_terms: D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects*; D005419:Flavonoids / Q000494:pharmacology*; D005697:Galactosides / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology*; D018922:HL-60 Cells / Q000187:drug effects; D006801:Humans; D044949:Kaempferols / Q000494:pharmacology*; D008745:Methylation; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D029626:Ranunculaceae / Q000737:chemistry*
chemical_list: D005419:Flavonoids; D005697:Galactosides; D006027:Glycosides; D044949:Kaempferols; D010936:Plant Extracts; C530019:trifolin acetate