title: Aneurysmal bone cysts recur at juxtaphyseal locations in skeletally immature patients.
abstract: Aneurysmal bone cysts are associated with a high rate of recurrence. Many aneurysmal bone cysts arise near open physes or articular cartilage in skeletally immature patients. Fear of damaging these structures could cause surgeons to curette the tumors less aggressively. We hypothesized location of an aneurysmal bone cyst in a periarticular or juxtaphyseal location would increase the risk of recurrence. We retrospectively studied 53 patients with aneurysmal bone cysts treated between 1989 and 2004. All patients had primary disease, and all patients underwent curettage of the lesion. Ten patients (18.9%) had local recurrence. Gender, race, and size did not predict recurrence; however 12 years of age or younger was associated with recurrence. Of the 19 juxtaphyseal cysts directly adjacent to an open physis, eight developed recurrence. Of the five periarticular cysts, two developed recurrence. The data suggest the risk of recurrence is highest in pediatric patients with juxtaphyseal or periarticular aneurysmal bone cysts. Meticulous treatment of these cysts is necessary, but we believe an overly aggressive approach that destroys the physis or articular cartilage is not warranted. Preservation of these structures remains a high priority of treatment.
authors.affiliation: Department of Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA. plin@mdanderson.org
authors.forename: Patrick P
authors.initials: PP
authors.lastname: Lin
authors.forename: Christopher
authors.initials: C
authors.lastname: Brown
authors.forename: A Kevin
authors.initials: AK
authors.lastname: Raymond
authors.forename: Michael T
authors.initials: MT
authors.lastname: Deavers
authors.forename: Alan W
authors.initials: AW
authors.lastname: Yasko
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017824:Bone Cysts, Aneurysmal / Q000000981:diagnostic imaging / Q000601:surgery*; D002357:Cartilage Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003475:Curettage / Q000009:adverse effects; D018483:Diaphyses / Q000000981:diagnostic imaging / Q000254:growth & development / Q000601:surgery*; D018572:Disease-Free Survival; D004838:Epiphyses / Q000000981:diagnostic imaging / Q000254:growth & development / Q000601:surgery*; D005260:Female; D006132:Growth Plate / Q000601:surgery; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome