[A case of long-term survival of 5 years after operation and chemotherapy for type 4 gastric cancer with peritoneal dissemination].
We report a case of long-term survival of 5 years after operation and chemotherapy for type 4 gastric cancer with peritoneal dissemination. A 41-year-old woman underwent total gastrectomy for type 4 gastric cancer with peritoneal dissemination and pancreas invasion. After operation, chemotherapy with S-1 plus PSK therapy, S-1 plus CDDP, and S-1 plus DOC was performed. The regimen of S-1 plus CDDP included S-1 on day 1-5, 8-12, 15-19, 22-26 and 2 weeks rest and PSK daily. After S-1 plus PSK therapy(34th course), peritoneal recurrence caused ileus, so a right hemicolonectomy was performed. Now the patient is undergoing weekly paclitaxel. The S-1 plus PSK therapy is able to prolong time to progression and has fewer adverse effects.
Yamada
Takanobu
T
Dept. of Surgery, Yokohama City University, School of Medicine.
Rino
Yasushi
Y
Wada
Nobuyuki
N
Yukawa
Norio
N
Saeki
Hiroyuki
H
Arai
Hiromasa
H
Kanari
Masahiro
M
Nakayama
Takahiro
T
Masuda
Munetaka
M
Oshiro
Hisashi
H
Imada
Toshio
T
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D013997:Time Factors