The role of heparan sulfate in the glomerular basement membrane.
Recent studies, including those by van den Hoven and colleagues, have challenged the classic negative-charge theory of glomerular filtration. However, the possibility remains that heparan sulfate in the glomerular basement membrane plays a role in maintaining the glomerular filtration barrier.
Morita
H
H
Division of Nephrology, Department of Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan. morita@showa-university-fujigaoka.gr.jp
Yoshimura
A
A
Kimata
K
K
D000818:Animals; D000838:Anions / Q000378:metabolism*; D050533:Glomerular Basement Membrane / Q000378:metabolism*; D006497:Heparan Sulfate / Q000378:metabolism*; D006801:Humans
D000838:Anions; D006497:Heparan Sulfate