Biliary complications after liver transplantation from maastricht category-2 non-heart-beating donors.
BACKGROUND
There are unresolved issues regarding the security of liver transplantation with non-heart-beating donors (NHBDs). Recently, an increased incidence of biliary complications, mainly intrahepatic ischemic-type biliary strictures, has been described after controlled NHBDs.


METHODS
We studied the incidence and risk factors for biliary complications among uncontrolled NHBDs recipients compared with a large population of HBD recipients.


RESULTS
Overall, 16.8% of patients in the HBD group and 41.7% of patients in the NHBD group suffered any type of biliary complication (P=0.66). However, the incidence of nonanastomotic biliary strictures was significantly greater in the NHBD group (P<0.001). Multivariate analysis showed that independent risk factors for nonanastomotic strictures were hepatic artery thrombosis (relative risk; 98.7) and receiving a liver from a NHBD (relative risk; 47.1).


CONCLUSIONS
If this type of donors is accepted as a source of liver organs, the high incidence of biliary complications should be considered and efforts should be made to decrease ischemic injury.
Suárez
Francisco
F
Liver Transplant Unit, Hospital Juan Canalejo, Xubias de Arriba, A Coruña.
Otero
Alejandra
A
Solla
Miguel
M
Arnal
Francisco
F
Lorenzo
Maria Jose
MJ
Marini
Milagros
M
Vázquez-Iglesias
José L
JL
Gómez
Manuel
M
D000328:Adult; D000368:Aged; D002780:Cholestasis, Intrahepatic / Q000209:etiology*; D006085:Graft Survival; D006323:Heart Arrest; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000145:classification*