Overview of membrane rafts.
Transient lateral microdomains (rafts) in cell membranes have been postulated to perform a number of important functions in normal cells, and are also thought to be critically involved in several pathological conditions. However, there are still a number of fundamental unanswered questions concerning the composition, size, dynamics, and stability of membrane rafts. These questions are currently being addressed by a number of sophisticated biophysical, biochemical, and computational methodologies.
McIntosh
Thomas J
TJ
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
D001671:Biochemistry / Q000379:methods; D001703:Biophysics / Q000379:methods; D003198:Computer Simulation; D008051:Lipid Bilayers / Q000378:metabolism; D021962:Membrane Microdomains / Q000737:chemistry* / Q000378:metabolism*; D008954:Models, Biological
D008051:Lipid Bilayers