title: [Interventions to enhance adherence of patients with HIV on ART: a literature review].
abstract: The introduction of potent antiretroviral therapy led to a reduction of mortality and morbidity associated with HIV in industrial countries. HIV infection has changed from a lethal disease to a chronic illness that can be treated effectively. It can be assumed, that people who receive correct treatment now have a normal life expectancy. However, one of the most crucial predictors to ensure the effectiveness of ART is a nearly perfect adherence to the medication regime. This literature review summarizes the evidence resulting from randomised controlled trials which were conducted to enhance medication adherence to antiretroviral therapy. It shows that effective programs need to combine several methods. Generalized short-term interventions are easier to be tested by randomized controlled trials. However, for nursing guidelines we suggest long-term programs which are tailored to the patient's needs.
authors.affiliation: Abteilung Klinische Pflegewissenschaft, Universitätsspital Basel, Schweiz. Sabine.Bigler@stud.unibas.ch
authors.forename: Sabine
authors.initials: S
authors.lastname: Bigler
authors.forename: Dunja
authors.initials: D
authors.lastname: Nicca
authors.forename: Rebecca
authors.initials: R
authors.lastname: Spirig
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage*; D015400:Clinical Nursing Research; D019317:Evidence-Based Medicine; D015658:HIV Infections / Q000451:nursing*; D006801:Humans; D010349:Patient Compliance; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents