title: Proteomic analysis of liver diseases: molecular mechanisms and biomarker discovery.
abstract: Liver diseases afflict more than 10% of the world population. Although the main risk factors are known and the population at risk is monitored, new biomarkers are urgently needed to allow early diagnosis and hence more effective therapeutic interventions. Here, we revise the contribution of proteomics to the study of liver diseases and its potential impact in the clinical practice is evaluated.
authors.affiliation: Division of Hepatology and Gene Therapy, CIMA, University of Navarra, 31008 Pamplona, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Santamaría
authors.forename: Javier
authors.initials: J
authors.lastname: Muñoz
authors.forename: Joaquín
authors.initials: J
authors.lastname: Fernández-Irigoyen
authors.forename: Laura
authors.initials: L
authors.lastname: Sesma
authors.forename: Leticia
authors.initials: L
authors.lastname: Odriozola
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Corrales
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D003300:Copper / Q000032:analysis; D006801:Humans; D007501:Iron / Q000032:analysis; D008107:Liver Diseases / Q000175:diagnosis* / Q000378:metabolism; D040901:Proteomics / Q000379:methods
chemical_list: D015415:Biomarkers; D003300:Copper; D007501:Iron