title: [Idiopathic pulmonary hemosiderosis treated with azathioprine in a child].
abstract: Idiopathic pulmonary hemosiderosis (IPH), the main cause of pulmonary hemosiderosis in children, is characterized by intermittent alveolar bleeding and hemosiderin-laden macrophages in sputum and in gastric lavage. The treatment is based on corticosteroids and cytotoxic drugs, under special conditions. We describe the case of a 7-year-old girl with IPH who achieved partial clinical remission with high doses of corticosteroids. However, the treatment had to be discontinued because the patient developed Cushing's syndrome. Treatment was started with an azathioprine-corticosteroid combination and then changed to azathioprine alone, which was maintained for four years, with excellent results.
authors.affiliation: Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. clemax@vetor.com.br
authors.forename: Clemax Couto
authors.initials: CC
authors.lastname: Sant'Anna
authors.forename: Angélica Almada
authors.initials: AA
authors.lastname: Horta
authors.forename: Mônica Tessinari Rangel
authors.initials: MT
authors.lastname: Tura
authors.forename: Maria de Fatima Bazhuni Pombo
authors.initials: Mde F
authors.lastname: March
authors.forename: Sidnei
authors.initials: S
authors.lastname: Ferreira
authors.forename: Rafaela Baroni
authors.initials: RB
authors.lastname: Aurilio
authors.forename: Débora Brandão
authors.initials: DB
authors.lastname: Vieira
mesh_terms: D001379:Azathioprine / Q000008:administration & dosage*; D002648:Child; D003480:Cushing Syndrome / Q000209:etiology; D005260:Female; D006486:Hemosiderosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography
chemical_list: D007166:Immunosuppressive Agents; D001379:Azathioprine