A novel HLA-DRB1 allele, HLA-DRB1*0465, was identified in a Hodgkin's lymphoma cell line.
The new human leucocyte antigen-DRB1*0465 allele was identified in the Hodgkin's lymphoma cell line KM-H2. This novel allele differs from the DRB1*0406 allele by a single nucleotide exchange at position 288 (211) (A-->T), which results in an arginine to tryptophan amino acid replacement at codon 90 in the new allele.
Witter
K
K
Laboratory of Immunogenetics, University Munich, Munich, Germany. klaus.witter@med.uni-muenchen.de
Mautner
J
J
Volgger
A
A
Zahn
R
R
Kauke
T
T
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D045744:Cell Line, Tumor; D017931:DNA Primers / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006650:Histocompatibility Testing; D006689:Hodgkin Disease / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide; D009626:Terminology as Topic
D017931:DNA Primers; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains