Catechol oxidase and phenoxazinone synthase activity of a manganese(II) isoindoline complex.
The mononuclear [Mn(6'Me(2)indH)(H(2)O)(2)(CH(3)CN)](ClO(4))(2) (6'Me(2)indH: 1,3-bis(6'-methyl-2'-pyridylimino)isoindoline) complex has been prepared and characterized by various techniques such as elemental analysis, IR, UV-visible and ESR spectroscopy. The title compound was suitable as catalyst for the catalytic oxidation of 3,5-di-tert-butylcatechol (3,5-DTBCH(2)) to 3,5-di-tert-butyl-1,2-benzoquinone (3,5-DTBQ) (catecholase activity), and o-aminophenol (OAPH) to 2-aminophenoxazine-3-one (APX) (phenoxazinone synthase activity) with dioxygen at ambient condition in good yields. Kinetic measurements revealed first-order dependence on the catalyst and dioxygen concentration and saturation type behavior with respect to the corresponding substrate. It was also found that the added triethylamine in both systems accelerates the reaction.
Kaizer
József
J
Department of Chemistry, University of Pannonia, H-8200 Veszprém, Hungary.
Baráth
Gábor
G
Csonka
Róbert
R
Speier
Gábor
G
Korecz
László
L
Rockenbauer
Antal
A
Párkányi
László
L
D004156:Catechol Oxidase / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D054833:Isoindoles / Q000737:chemistry / Q000494:pharmacology*; D007700:Kinetics; D008345:Manganese / Q000737:chemistry*; D008958:Models, Molecular; D010088:Oxidoreductases / Q000378:metabolism*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D054833:Isoindoles; D008345:Manganese; D010088:Oxidoreductases; D004156:Catechol Oxidase; C023944:2-aminophenol oxidase