title: [Digital ischemia of a patient with undifferentiated large cell lung cancer].
abstract: A Raynaud's phenomenon with acral ischemia till necrosis is a rare form of a paraneoplasia. We report about a woman with a metastatic lung cancer, who was admitted because of pain in her left hand with necrosis of the fingertips and of the fifth right toe. We started a treatment with the intravenous vasodilator Iloprost, but the necroses progressed to gangrene. The course of a paraneoplastic syndrome is often determined by the underlying malignoma and if the antineoplastic treatment is ineffective, the chances to treat the paraneoplasia may be limited.
authors.affiliation: Stadtspital Triemli, Zürich.
authors.forename: I
authors.initials: I
authors.lastname: Schmid
authors.forename: M
authors.initials: M
authors.lastname: Fliegner
mesh_terms: D018287:Carcinoma, Large Cell / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000628:therapy; D011928:Raynaud Disease / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy