Molecular motors: a surprising twist in myosin VI translocation.
A recent study has revealed an unexpected change in conformation of the myosin VI converter domain, essential for twisting the lever arm through a approximately 180 degrees rotation to achieve a large step along actin.
Spudich
James A
JA
Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA. jspudich@stanford.edu
D000199:Actins / Q000378:metabolism*; D000818:Animals; D001696:Biomechanical Phenomena; D020409:Molecular Motor Proteins / Q000378:metabolism; D018995:Myosin Heavy Chains / Q000378:metabolism*; D011487:Protein Conformation
D000199:Actins; D020409:Molecular Motor Proteins; C089785:myosin VI; D018995:Myosin Heavy Chains