title: Thyroid microcarcinoma during thyroidectomy.
abstract: BACKGROUND
  We aimed to retrospectively assess the prevalence of microcarcinoma in thyroidectomy specimens from a Greek population and the role of histopathology in determining management of these patients.
  
  
  METHODS
  We used histopathological reports of thyroidectomies performed in a Greek general district hospital. The samples consisted of 191 thyroidectomies performed between January 1997 and July 2001. The female:male ratio was approximately 2:1 and the follow-up period was 327 weeks.
  
  
  RESULTS
  There were 29 microcarcinomas (15.2 percent) with a female:male ratio of 6:1. The prevalence rate in cases with Hashimoto's thyroiditis was significantly higher compared to cases with other benign thyroid pathology (26.8 percent versus 11.9 percent, p-value equals 0.02). Eight microcarcinomas (27.6 percent) were multifocal. The histological type was that of papillary tumour in ten cases (34.5 percent) and follicular in 18 cases (62.1 percent). There were no deaths, recurrences or metastases during the follow-up period.
  
  
  CONCLUSIONS
  Our results suggest that incidental microcarcinomas are low-risk tumours that do not require routine further intervention. The latter may be necessary for tumours with poor differentiation or for non-incidental microcarcinomas.
authors.affiliation: Department of Obstetrics and Gynaecology, Southmead University Hospital, Westbury-on-Trym, Bristol BS10 5NB, The United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Siassakos
authors.forename: S
authors.initials: S
authors.lastname: Gourgiotis
authors.forename: P
authors.initials: P
authors.lastname: Moustafellos
authors.forename: N
authors.initials: N
authors.lastname: Dimopoulos
authors.forename: E
authors.initials: E
authors.lastname: Hadjiyannakis
mesh_terms: D001707:Biopsy, Needle; D002277:Carcinoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D050031:Hashimoto Disease / Q000175:diagnosis; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008495:Medical Oncology / Q000379:methods*; D012306:Risk; D013964:Thyroid Neoplasms / Q000175:diagnosis*; D013965:Thyroidectomy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome