title: Primary Sjogren's syndrome complicated by bilateral pleural effusion.
abstract: Sjogren's syndrome can cause many organic changes, but is rarely accompanied by pleuritis. We report a 65-year-old patient with primary Sjogren's syndrome who developed bilateral pleuritis with moderately large effusions. He was diagnosed as having Sjogren's syndrome, based on xerophthalmia, xerostomia, positive results for anti-Sjogren's syndrome (anti-SS-A/SS-B) antibodies, the Schirmer test and biopsy findings in the minor salivary glands. The pleural fluid was lymphocyte rich and contained high levels of anti-SS-A/SS-B antibodies. There was no evidence of infection, malignancy or other collagen diseases which cause pleuritis. We conclude that this case adds to the eight previously published reports of primary Sjogren's syndrome complicated by pleural effusion.
authors.affiliation: Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan.
authors.forename: Katsunobu
authors.initials: K
authors.lastname: Teshigawara
authors.forename: Satoru
authors.initials: S
authors.lastname: Kakizaki
authors.forename: Madoka
authors.initials: M
authors.lastname: Horiya
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Tetsu
authors.initials: T
authors.lastname: Hashida
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tomizawa
authors.forename: Naondo
authors.initials: N
authors.lastname: Sohara
authors.forename: Ken
authors.initials: K
authors.lastname: Sato
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Takagi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Matsuzaki
authors.forename: Masatomo
authors.initials: M
authors.lastname: Mori
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D010996:Pleural Effusion / Q000209:etiology*; D010998:Pleurisy / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis*