title: [Childhood hypoglycemia: results of prospective evaluation protocols in children with up to 1 year of age].
abstract: The aim of this study is to present the experience of applying hypoglycemia evaluation protocol. We performed a prospective study with 13 children with hypoglycemia symptoms at the Hospital of Clinicas of Porto Alegre, with range age 5.3+/-4.5 months and eight patients are female. The patients had been submitted to glucagon fasting test and blood glucose, lactate, pH, C peptide, insulin, fatty acids, TSH, GH, cortisol, and urine ketones were measured. Eight patients presented persistent hypoglycemia and five presented transitory hypoglycemia. The most frequent diagnosis was persistent hyperinsulinism. We suggest the use of a simple protocol for the evaluation of hypoglycemia, which contemplates the identifications of the main etiologies in children and facilitates the handling of these patients.
authors.affiliation: Serviço de Endocrinologia, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS. tcostarodrigues@terra.com.br
authors.forename: Ticiana C
authors.initials: TC
authors.lastname: Rodrigues
authors.forename: Maikel
authors.initials: M
authors.lastname: Colli
authors.forename: Mauro A
authors.initials: MA
authors.lastname: Czepielewski
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D005215:Fasting; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006863:Hydrogen-Ion Concentration; D006946:Hyperinsulinism / Q000175:diagnosis* / Q000209:etiology; D007003:Hypoglycemia / Q000175:diagnosis* / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D007328:Insulin / Q000097:blood; D007657:Ketone Bodies / Q000652:urine; D007773:Lactates / Q000097:blood; D008297:Male; D010455:Peptides / Q000097:blood; D011446:Prospective Studies; D013972:Thyrotropin / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D007657:Ketone Bodies; D007773:Lactates; D010455:Peptides; C050632:polypeptide C; D013972:Thyrotropin; D006854:Hydrocortisone