title: Aggressive angiomyxoma of supraclavicular fossa: a case report.
abstract: BACKGROUND
  Aggressive angiomyxoma (AAM) is a rare myxoid mesenchymal tumor that occurs almost exclusively in the adult pelvic-perineal region and predominantly in females. Only 1 case of AAM occurring outside this region has been reported. Here we report another such case.
  
  
  METHODS
  The patient was referred for evaluation of a firm nonmovable mass of the supraclavicular fossa that had progressively enlarged within the previous year. MRI showed an infiltrative growth pattern with adhesion to adjacent anatomic structures. Wide excision was attempted, but a clear margin could not be achieved.
  
  
  RESULTS
  The histopathology revealed characteristic features of AAM, including stellate to spindle-shaped tumor cells set in a myxoid background, with hyalinizing thick-walled vessels and characteristic immunophenotype.
  
  
  CONCLUSIONS
  Accurate diagnosis and a definite surgical margin are crucial because AAM is locally aggressive and easily recurrent. Our case deserves attention because it shows that AAM may exist in the head and neck.
authors.affiliation: Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
authors.forename: Chien-Yu
authors.initials: CY
authors.lastname: Pai
authors.forename: Shin
authors.initials: S
authors.lastname: Nieh
authors.forename: Jih-Chin
authors.initials: JC
authors.lastname: Lee
authors.forename: Chung-Ping
authors.initials: CP
authors.lastname: Lo
authors.forename: Herng-Sheng
authors.initials: HS
authors.lastname: Lee
mesh_terms: D002968:Clavicle; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D011859:Radiography