Fatal neonatal stroke from a prenatal cardiac thrombus.
Despite careful investigation, the etiology of many perinatal arterial strokes is unknown. We report on a 5-day-old boy with a cardiac thrombus of prenatal origin resulting in a fatal postnatal stroke. The thrombus was discovered only at autopsy, challenging the assumption of a placental source of embolus in perinatal strokes in the absence of macroscopic and microscopic examination of the heart.
Amlie-Lefond
Catherine M
CM
Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. Klefond@mcw.edu
Basir
Mir A
MA
Franciosi
Ralph A
RA
D000138:Acidosis / Q000209:etiology; D001344:Autopsy; D001929:Brain Edema / Q000151:congenital / Q000473:pathology; D003328:Coronary Thrombosis / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D005315:Fetal Diseases; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009206:Myocardium / Q000473:pathology; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology; D020521:Stroke / Q000151:congenital* / Q000209:etiology* / Q000473:pathology; D013610:Tachycardia / Q000209:etiology; D014057:Tomography, X-Ray Computed