Recent trends in the surgical management of inflammatory bowel disease.
Surgery is required in the vast majority of patients with Crohn's disease (CD) and in approximately one-third of patients with ulcerative colitis (UC). Similar to medical treatments for IBD, significant advances have occurred in surgery. Advances in CD include an emphasis upon conservatism as exemplified by more limited resections, strictureplasties, and laparoscopic resections. The use of probiotics in selected patients has improved the outcome in patients with pouchitis following restorative proctocolectomy for UC. It is anticipated that ongoing discoveries in the molecular basis of IBD will in turn identify those patients who will best respond to surgery.
Roses
Robert E
RE
University of Pennsylvania School of Medicine, Philadelphia, PA 19140, USA.
Rombeau
John L
JL
D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000473:pathology / Q000601:surgery*; D016737:Proctocolectomy, Restorative