title: Growth and nutrition: the first six months.
abstract: Today the WHO Growth Chart Standards, based on the growth of breastfed infants, are used. These growth curves solve the problem of the deviating observations for breastfed compared to non-breastfed infants using previous growth charts. Presently it is not clear how the mother's diet, especially the fat intake, influences the growth of the offspring. Animal experiments indicate that a low intake of n-3 polyunsaturated fatty acids via the milk may have short- and long-term negative consequences. There is limited information in man. It has been suggested that the mammary glands may have phylogenetically originated from glands providing innate immunity, later developing capacities for providing nutrition. This would agree with the fact that human milk contains so many major components which do not primarily function as nutrients, but seem to protect nutrition and growth. Lactoferrin, oligosaccharides, glycoproteins, secretory IgA antibodies, alpha-lactalbumin and the antisecretory factor have such functions.
authors.affiliation: Department of Clinical Immunology, Göteborg University, Göteborg, Sweden. lars.hanson@immuno.gu.se
authors.forename: Lars A
authors.initials: LA
authors.lastname: Hanson
authors.forename: Shakila
authors.initials: S
authors.lastname: Zaman
authors.forename: B
authors.initials: B
authors.lastname: Werner
authors.forename: Liliana
authors.initials: L
authors.lastname: Håversen
authors.forename: Cecilia
authors.initials: C
authors.lastname: Motas
authors.forename: Magda
authors.initials: M
authors.lastname: Moisei
authors.forename: Inger
authors.initials: I
authors.lastname: Mattsby-Baltzer
authors.forename: Stefan
authors.initials: S
authors.lastname: Lange
authors.forename: Mahnaz
authors.initials: M
authors.lastname: Banasaz
authors.forename: Tore
authors.initials: T
authors.lastname: Midtvedt
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Norin
authors.forename: Sven-Arne
authors.initials: SA
authors.lastname: Silfverdal
mesh_terms: D001903:Bottle Feeding; D001942:Breast Feeding; D002657:Child Development; D004042:Dietary Fats, Unsaturated / Q000378:metabolism*; D005260:Female; D006130:Growth Disorders / Q000178:diet therapy / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007223:Infant; D007228:Infant Nutrition Disorders / Q000178:diet therapy / Q000209:etiology / Q000517:prevention & control; D007227:Infant Nutritional Physiological Phenomena / Q000502:physiology*; D007231:Infant, Newborn / Q000254:growth & development*; D008297:Male; D008895:Milk, Human / Q000737:chemistry* / Q000276:immunology
chemical_list: D004042:Dietary Fats, Unsaturated