Novel approach for the synthesis of Fe3O4@TiO2 core-shell microspheres and their application to the highly specific capture of phosphopeptides for MALDI-TOF MS analysis.
A novel approach is proposed to synthesize Fe(3)O(4)@TiO(2) microspheres with a well-defined core-shell structure, and the synthesized Fe(3)O(4)@TiO(2) core-shell microspheres were successfully applied for the simple and fast enrichment of phosphopeptides via direct MALDI-TOF mass spectrometry analysis.
Li
Yan
Y
Department of Chemistry, Fudan University, Shanghai 200433, China.
Wu
Jinsong
J
Qi
Dawei
D
Xu
Xiuqing
X
Deng
Chunhui
C
Yang
Pengyuan
P
Zhang
Xiangmin
X
D052203:Ferrosoferric Oxide / Q000737:chemistry*; D008863:Microspheres; D010316:Particle Size; D010748:Phosphopeptides / Q000737:chemistry* / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D013499:Surface Properties; D053719:Tandem Mass Spectrometry / Q000379:methods; D014025:Titanium / Q000737:chemistry*
D010748:Phosphopeptides; C009495:titanium dioxide; D014025:Titanium; D052203:Ferrosoferric Oxide