Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients.
African histoplasmosis caused by Histoplasma capsulatum var. duboisii is an invasive fungal infection endemic in central and west Africa. Most of its ecology and pathogenesis remain unknown. H. capsulatum var. capsulatum is an AIDS-defining opportunistic infection in HIV-infected patients who are living in or have traveled to histoplasmosis-endemic areas. In contrast, reports concerning African histoplasmosis during HIV infection are rare, although both pathogens coexist in those regions. We report 3 cases of imported African histoplasmosis diagnosed in France in HIV-infected patients and a literature review on similar cases.
Loulergue
Pierre
P
University Paris V, Paris, France.
Bastides
Frédéric
F
Baudouin
Véronique
V
Chandenier
Jacques
J
Mariani-Kurkdjian
Patricia
P
Dupont
Bertrand
B
Viard
Jean-Paul
JP
Dromer
Françoise
F
Lortholary
Olivier
O
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000821:virology*; D006801:Humans; D008297:Male