title: Metabolic syndrome rates in United States adolescents, from the National Health and Nutrition Examination Survey, 1999-2002.
abstract: OBJECTIVE
  To report the prevalence rates of the metabolic syndrome in a nationally representative sample of adolescents in the United States using 4 previously reported definitions of the syndrome.
  
  
  METHODS
  Data from 12- to 19-year-old adolescents included in the National Health and Nutrition Examination Survey from 1999 to 2002 (NHANES 99-02) were analyzed by cross-sectional methods, by using 4 definitions of the metabolic syndrome previously applied to adolescents.
  
  
  RESULTS
  In NHANES 99-02, the prevalence of the metabolic syndrome in all teens varied from 2.0% to 9.4% of teens in the United States, depending on the definition used. In obese teens, these prevalence rates varied from 12.4% to 44.2%. In the group of obese teens, application of the definition by Cruz produced a metabolic syndrome prevalence rate of 12.4%; that of Caprio produced a rate of 14.1%. However, none of the normal weight or overweight teens met either definition. Application of the definition by Cook produced a prevalence rate of 7.8% in overweight teens and 44% in obese teens. The adult definition of metabolic syndrome produced a prevalence rate of 16% in overweight teens and 26% in obese teens.
  
  
  CONCLUSIONS
  In the period between 1999 and 2002, the prevalence rate of metabolic syndrome varied from just >9% to as low as 2% of adolescents overall. Different definitions of metabolic syndrome generated prevalence rates in obese adolescents that varied widely from 12% to 44%. For this syndrome to be a useful construct, a more standardized set of criteria may be needed.
authors.affiliation: Division of General Pediatrics and Strong Children's Research Center, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York.
authors.forename: Stephen
authors.initials: S
authors.lastname: Cook
authors.forename: Peggy
authors.initials: P
authors.lastname: Auinger
authors.forename: Chaoyang
authors.initials: C
authors.lastname: Li
authors.forename: Earl S
authors.initials: ES
authors.lastname: Ford
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015994:Incidence; D008075:Lipoproteins, HDL / Q000378:metabolism; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000453:epidemiology*; D009749:Nutrition Surveys; D009765:Obesity / Q000150:complications; D050177:Overweight; D010372:Pediatrics / Q000592:standards; D014481:United States
chemical_list: D008075:Lipoproteins, HDL