title: Enhanced rate of resting energy expenditure in women using hormone-replacement therapy: preliminary results.
abstract: Hormone-replacement therapy (HRT) attenuates the menopause-associated alterations in body composition. It is not known, however, whether this effect is a result of a concomitant increase in energy expenditure. The authors examined whether women submitted to a long-term HRT treatment presented greater energy expenditure than women who had never used HRT. We compared 13 postmenopausal women using HRT (>1 yr) with 13 age- (+/-2 yr) and body-mass-index-matched (BMI; +/-1.5 kg/m2) postmenopausal women not using HRT. Resting energy expenditure (REE; indirect calorimetry), body composition, and daily (DEE) and physical activity (PAEE) energy expenditure (accelerometry) were obtained. Although BMI, fat mass, fat-free mass, DEE, and PAEE were similar between groups, the HRT group displayed a significantly greater REE than the no-HRT group (Delta +222 kcal/day). In conclusion, the authors observed that a long-term treatment with HRT is associated with a greater REE in postmenopausal women. These results need to be confirmed.
authors.affiliation: Research Centre on Aging, Faculty of Physical Education and Sports, University of Sherbrooke, Sherbrooke, QC, Canada.
authors.forename: Mylène
authors.initials: M
authors.lastname: Aubertin-Leheudre
authors.forename: Eric D B
authors.initials: ED
authors.lastname: Goulet
authors.forename: Isabelle J
authors.initials: IJ
authors.lastname: Dionne
mesh_terms: D000368:Aged; D001823:Body Composition / Q000502:physiology; D002153:Calorimetry, Indirect; D003627:Data Interpretation, Statistical; D004734:Energy Metabolism / Q000502:physiology*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008593:Menopause / Q000502:physiology; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology