Non-heme hydroxylase engineering for simple enzymatic synthesis of L-threo-hydroxyaspartic acid.
Strieker
Matthias
M
Chemistry and Biochemistry Department, Philipps-University Marburg, Hans-Meerwein-Strasse, 35032 Marburg, Germany.
Essen
Lars-Oliver
LO
Walsh
Christopher T
CT
Marahiel
Mohamed A
MA
D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D017931:DNA Primers; D006900:Hydroxylation; D013058:Mass Spectrometry; D006899:Mixed Function Oxygenases / Q000235:genetics / Q000378:metabolism*; D016297:Mutagenesis, Site-Directed; D015202:Protein Engineering; D013237:Stereoisomerism; D013379:Substrate Specificity
D017931:DNA Primers; C011274:3-hydroxyaspartic acid; D001224:Aspartic Acid; D006899:Mixed Function Oxygenases