title: Nonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.
abstract: OBJECTIVE
  To assess the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on bleeding for pediatric adenotonsillectomy in a retrospective study, based on the common practices at 2 different tertiary care facilities.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  Two different tertiary care facilities.
  
  
  METHODS
  Children up to 16 years of age, who underwent elective adenotonsillectomy or tonsillectomy, were included in the study. All indications for adenotonsillectomy, and all surgical techniques were included. Children with a bleeding tendency, and those with contraindications to the use of NSAIDs (eg, because of allergy), were excluded from the study.
  
  
  METHODS
  Nonsteroidal anti-inflammatory drugs.
  
  
  METHODS
  Postoperative bleeding in patients.
  
  
  RESULTS
  A total of 1160 patients were selected who met the criteria: 673 patients underwent an adenotonsillectomy or tonsillectomy and did not receive any preoperative and postoperative ibuprofen, and 487 patients underwent routine adenotonsillectomy or tonsillectomy and were given postoperative ibuprofen. We noted a 0.7% postoperative bleeding rate in patients who were not allowed to take ibuprofen perioperatively. There was a 1.0% postoperative bleeding rate in patients who were allowed to take ibuprofen perioperatively (P = .75).
  
  
  CONCLUSIONS
  Ibuprofen is not a contraindication to adenotonsillectomy or tonsillectomy and should be used in the control of postoperative pain if it is indicated in the patient.
authors.affiliation: Department of Otolaryngology, Washington University School of Medicine, St Louis, MO 63110, USA. jeyakumara@ent.wustl.edu
authors.forename: Anita
authors.initials: A
authors.lastname: Jeyakumar
authors.forename: Todd M
authors.initials: TM
authors.lastname: Brickman
authors.forename: Mary E
authors.initials: ME
authors.lastname: Williamson
authors.forename: Keiko
authors.initials: K
authors.lastname: Hirose
authors.forename: Paul
authors.initials: P
authors.lastname: Krakovitz
authors.forename: Kenneth
authors.initials: K
authors.lastname: Whittemore
authors.forename: Christopher
authors.initials: C
authors.lastname: Discolo
mesh_terms: D000233:Adenoidectomy; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010149:Postoperative Pain / Q000517:prevention & control; D019106:Postoperative Hemorrhage / Q000139:chemically induced*; D012189:Retrospective Studies; D014068:Tonsillectomy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal