title: Metastatic brain tumor surgery using fluorescein sodium: technical note.
abstract: As for the surgical treatment of glioma, the recent employment of fluorescence-guided resection using 5-aminolevulinic acid (5-ALA) or high-dose fluorescein sodium has increased the rate of radical tumor resection. On the other hand, there is no specific technique for metastatic brain tumor surgery. We have used a fluorescence-guided tumor resection procedure with the aid of high-dose fluorescein sodium in surgery for metastatic brain tumor. Fluorescein sodium has been used in 13 cases, and achieved effective stainability in all cases. Fluorescein sodium is inexpensive, highly safe, and comparatively easy to use, and does not require any special equipment. We believe that the use of fluorescein sodium is beneficial for resection of the metastatic brain tumor.
authors.affiliation: Department of Neurosurgery, Kinki University School of Medicine, Osaka, Japan. okuda@neuro-s.med.kindai.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Okuda
authors.forename: K
authors.initials: K
authors.lastname: Kataoka
authors.forename: M
authors.initials: M
authors.lastname: Taneda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery*; D002277:Carcinoma / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery*; D004396:Coloring Agents; D005260:Female; D019793:Fluorescein; D005456:Fluorescent Dyes; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods*; D009778:Occipital Lobe / Q000473:pathology / Q000601:surgery; D010777:Photochemistry; D011237:Predictive Value of Tests; D013194:Staining and Labeling / Q000379:methods; D016896:Treatment Outcome
chemical_list: D004396:Coloring Agents; D005456:Fluorescent Dyes; D019793:Fluorescein