title: Atrophy of the intrinsic musculature of the hands associated with the use of botulinum toxin-A injections for hyperhidrosis: a case report and review of the literature.
abstract: Botulinum toxin type A (BTX-A) has been used therapeutically for the treatment of spastic disorders for many years. More recently, the therapeutic utility of BTX-A in the treatment of hyperhidrosis has been recognised. While studies have reported on the efficacy of BTX-A in managing hyperhidrosis, long term data are required in order for the treatment implications to be fully appreciated. We report on a case of severe atrophy of the intrinsic muscles of the hands in a patient treated with intra-palmar BTX-A (Dysport, Speywood, UK) injections for hyperhidrosis. To our knowledge this has not been described in the literature before.
authors.affiliation: Department of Plastic and Reconstructive Surgery, St. Georges Hospital, Tooting, London SW17 0QT, UK. graemeglass@hotmail.com
authors.forename: G E
authors.initials: GE
authors.lastname: Glass
authors.forename: M
authors.initials: M
authors.lastname: Hussain
authors.forename: A N M
authors.initials: AN
authors.lastname: Fleming
authors.forename: B W E M
authors.initials: BW
authors.lastname: Powell
mesh_terms: D000293:Adolescent; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy*; D007271:Injections, Intradermal; D009133:Muscular Atrophy / Q000139:chemically induced*; D009498:Neurotoxins / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D009498:Neurotoxins; D019274:Botulinum Toxins, Type A