title: [Case of urticaria due to cochineal dye in red-colored diet].
abstract: We herein describe a 33-year-old female who recurrently exhibited urticaria accompanied by vomiting, diarrhea and dyspnea after taking red-colored food. From her history, we suspected the cochineal dye, the commonly used natural red dye in red-colored food and beverage, to be the cause of her symptoms. Oral provocation test using cochineal dye-stained red-colored boiled-fish-paste induced urticaria and respiratory symptoms. Furthermore the prick tests and the scratch tests with cochineal dye and carminic acid, the major ingredient of cochineal dye, were also positive. These results indicate that type 1 allergy to cochineal dye caused urticaria in this patient. Thereafter, she avoided the foods containing a cochineal dye and showed a complete clinical remission. Recently, the number of literatures described about increased incidence of type 1 allergy to cochineal dye. As the usage of cochineal dye is increasing in the Japanese market, we should keep in mind that cochineal dye can be a cause of urticaria in daily practice.
authors.affiliation: Department of Dermatology, Osaka University.
authors.forename: Yorihisa
authors.initials: Y
authors.lastname: Kotobuki
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Azukizawa
authors.forename: Youko
authors.initials: Y
authors.lastname: Nishida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Murota
authors.forename: Ichiro
authors.initials: I
authors.lastname: Katayama
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Yoshikawa
mesh_terms: D000328:Adult; D002329:Carmine / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005505:Food Coloring Agents / Q000009:adverse effects*; D006801:Humans; D012882:Skin Tests; D014581:Urticaria / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
chemical_list: D005505:Food Coloring Agents; D002329:Carmine