title: Benzothiazines in synthesis: studies directed toward the synthesis of erogorgiaene.
abstract: The use of benzothiazenes for the formal total synthesis of erogorgiaene and stereoselective total syntheses of two diastereomers of this natural product is described. In particular, the stereochemical course of a radical cyclization anticipated to give the correct relative stereochemistry for the synthesis of erogorgiaene is discussed utilizing both experimental and computational data.
authors.affiliation: Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA. harmatam@missouri.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Harmata
authors.forename: Xuechuan
authors.initials: X
authors.lastname: Hong
authors.forename: Peter R
authors.initials: PR
authors.lastname: Schreiner
mesh_terms: D004224:Diterpenes / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013843:Thiazines / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D013843:Thiazines; C428183:erogorgiaene