title: [Assessment of efficacy of arterial infusion chemotherapy with gemcitabine for four cases of advanced pancreatic cancer].
abstract: We treated 4 cases of advanced pancreatic cancer: 2 cases were nonresectable and the other 2 cases did not choose an operation but arterial infusion chemotherapy with gemcitabine after the transcatheter peripancreatic arterial embolizaiton. One case resulted in a tumor decrease but the other 3 cases observed a tumor progress. Although we confirmed cancer pain suppression in all cases and a disappearance of tumor fever in one case, the survival period was 7 months in spite of the treatment. As for the complication of arterial infusion chemotherapy with gemcitabine, we recognized bone marrow suppression (grade 1) in 3 cases. This therapy seemed to be effective for suppression of pain and tumor fever caused from the advanced pancreatic cancer. However, we need to improve in survival period from this therapy.
authors.affiliation: Dept. of Surgery, Miyazaki Prefectural Nobeoka Hospital.
authors.forename: Koichi
authors.initials: K
authors.lastname: Doi
authors.forename: Tetsufumi
authors.initials: T
authors.lastname: Ohchi
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Ogata
authors.forename: Akinobu
authors.initials: A
authors.lastname: Matsuo
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kudoh
authors.forename: Ryu
authors.initials: R
authors.lastname: Ohtao
authors.forename: Takahiro
authors.initials: T
authors.lastname: Muranaka
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D000093542:Gemcitabine
chemical_list: D014408:Biomarkers, Tumor; D003841:Deoxycytidine; D000093542:Gemcitabine