Poly(beta-aminosulfonamides) as gene delivery vectors: synthesis and in vitro screening.
A series of poly(beta-aminosulfonamides) was synthesized and demonstrated to be efficient in vitro transfection reagents.
Gan
Lin
L
Department of Chemistry and James Franck Institute, University of Chicago, CIS E419A, 929 E. 57th St., Chicago, IL 60637, USA.
Olson
Jennifer L
JL
Ragsdale
Clifton W
CW
Yu
Luping
L
D000818:Animals; D019556:COS Cells; D002522:Chlorocebus aethiops; D004247:DNA / Q000737:chemistry / Q000235:genetics*; D018014:Gene Transfer Techniques; D006863:Hydrogen-Ion Concentration; D008156:Luciferases / Q000235:genetics / Q000378:metabolism; D015394:Molecular Structure; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
D011108:Polymers; D013449:Sulfonamides; D004247:DNA; D008156:Luciferases