[Hepatic involvement in celiac disease].
Celiac disease (CD) is an autoimmune enteropathy triggered by gluten ingestion in genetically susceptible individuals. Hypertransaminasemia has been observed in up to 40% of untreated celiac patients and is usually resolved by a gluten-free diet. The most common type of liver disease associated with CD is non-specific reactive hepatitis, while association with viral hepatitis or autoimmune-mediated liver diseases such as autoimmune hepatitis, primary biliary cirrhosis or primary sclerosing cholangitis is less frequent. Therefore, a practical recommendation would be to look for liver disfunction in patients with CD as well as to perform diagnostic tests for CD in patients with hypertransaminasemia or cholestasis of unknown etiology.
Barbero Villares
Almudena
A
Servicio de Aparato Digestivo, Unidad de Hepatología, Hospital Universitario de La Princesa, Universidad Autónoma, Madrid, España. albavi79@hotmail.com
Moreno Monteagudo
José Andrés
JA
Moreno Borque
Ricardo
R
Moreno Otero
Ricardo
R
D002446:Celiac Disease / Q000150:complications*; D006801:Humans; D008107:Liver Diseases / Q000209:etiology*