Fearful faces selectively increase corticospinal motor tract excitability: a transcranial magnetic stimulation study.
Fearful facial expressions are danger signals that rapidly trigger a cascade of neurobiological processes defensibly associated with action preparation. However, direct evidence for the activating effects of fearful facial expressions on the motor system is absent. The current transcranial magnetic stimulation (TMS) study investigated whether fearful facial expressions selectively increase corticospinal motor tract (CST) excitability. Focal TMS was applied over the left primary motor cortex during the exposure of fearful, happy, and neutral facial expressions in 12 healthy right-handed volunteers. Changes in CST excitability using the motor evoked potential (MEP) were recorded. Results showed significant selective increases in MEP to fearful facial expressions. These findings provide the first direct evidence for selective increases in CST excitability to threat and contribute to evolutionary views on emotion and action preparedness.
Schutter
Dennis J L G
DJ
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands. d.schutter@uu.nl
Hofman
Dennis
D
Van Honk
Jack
J
D000328:Adult; D003627:Data Interpretation, Statistical; D004525:Efferent Pathways / Q000502:physiology*; D004576:Electromyography; D019054:Evoked Potentials, Motor / Q000502:physiology; D005149:Facial Expression; D005239:Fear / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011712:Pyramidal Tracts / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation