title: Transmission of type 1 diabetes by bone marrow transplantation: a case report.
abstract: T1D after BMT constitutes a human model of autoimmune disease transmission. This case report refers to T1D onset after allogeneic HLA-matched BMT in a six-yr-old recipient affected by aplastic anemia. The donor was his sister who had T1D. The recipient had a complication free course apart from grade 1 acute GVHD, which was resolved spontaneously. With the predictive value and significance of T1D-associated autoantibodies, we tried to consolidate the T1D transfer possibility based on our patient characteristics and a literature review.
authors.affiliation: Service d'Immuno-Hématologie pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia. melloulif@yahoo.fr
authors.forename: Fethi
authors.initials: F
authors.lastname: Mellouli
authors.forename: Habib
authors.initials: H
authors.lastname: Ksouri
authors.forename: Lamia
authors.initials: L
authors.lastname: Torjmen
authors.forename: Abderrahman
authors.initials: A
authors.lastname: Abdelkefi
authors.forename: Saloua
authors.initials: S
authors.lastname: Ladeb
authors.forename: Tarek
authors.initials: T
authors.lastname: Ben Othman
authors.forename: Assia
authors.initials: A
authors.lastname: Ben Hassen
authors.forename: Mohamed
authors.initials: M
authors.lastname: Béjaoui
mesh_terms: D000741:Anemia, Aplastic / Q000601:surgery; D001323:Autoantibodies / Q000032:analysis; D016026:Bone Marrow Transplantation / Q000276:immunology*; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D006086:Graft vs Host Disease / Q000453:epidemiology; D006801:Humans; D008297:Male; D014019:Tissue Donors
chemical_list: D001323:Autoantibodies