title: [A long-term survival case of unresectable hepatohilar bile duct cancer treated with radiotherapy and hepatic arterial infusion chemotherapy ].
abstract: The patient, a 79-year-old woman, underwent distal gastrectomy for gastric cancer in November 2002. The lesion was judged to be T1 N0H0POM0 and fStage IA. A hepatohilar tumor was found 1 year after gastrectomy by CT scan. Radiological examinations revealed a presence of right portal vein stenosis and left portal vein obstruction due to hepatohilar bile duct cancer. Surgical treatment was considered to be difficult because of the consequence of the tumor involved in the right hepatic artery. We performed hepatic arterial infusion chemotherapy of 5-fluorouracil 1000 mg/body/week for 8 courses through the reservoir catheter. Radiation therapy was delivered concurrently with hepatic arterial infusion. The condition of the patient was good after receiving 40 Gy, Three months after the additional 20 Gy radiation, the tumor was markedly reduced in size, and was not detected 7 months thereafter. MRI showed no recurrence for three and a half years since chemo-radiation.
authors.affiliation: Dept. of Gastroenterological Surgery, Kansai Rousai Hospital.
authors.forename: Keishi
authors.initials: K
authors.lastname: Sugimoto
authors.forename: Shin
authors.initials: S
authors.lastname: Nakahira
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Miki
authors.forename: Ken
authors.initials: K
authors.lastname: Nakata
authors.forename: Shu
authors.initials: S
authors.lastname: Okamura
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okada
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Miyake
authors.forename: Mio
authors.initials: M
authors.lastname: Yoshimura
authors.forename: Kumiko
authors.initials: K
authors.lastname: Uji
authors.forename: Atsuko
authors.initials: A
authors.lastname: Yoshida
authors.forename: Rei
authors.initials: R
authors.lastname: Suzuki
authors.forename: Masato
authors.initials: M
authors.lastname: Komori
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Tamura
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D008279:Magnetic Resonance Imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D005472:Fluorouracil