Tropical mayhem: a chronic viral disease with superadded parasitic infection.
Coexistence of two illnesses in the same patient may result in atypical manifestations of either or both diseases. A case of hepatitis B virus-related cirrhosis in a patient who presented with a pharyngeal mucosal mass lesion as a manifestation of superadded Leishmania infection is presented here. The clue to the diagnosis was the origin of the patient from an area highly endemic for leishmaniasis and the presence of unexplained polyclonal hypergammaglobulinaemia. The patient responded very well to therapy with amphotericin B with complete disappearance of the mucosal lesion.
Madan
Kaushal
K
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Chalamalsetty
Sreenivasa Baba
SB
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Srivastava
Siddharth
S
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Gupta
Siddhartha Datta
SD
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Mirdha
Bijay R
BR
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Makharia
Govind K
GK
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Samataray
Jyotish C
JC
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Acharya
Subrat K
SK
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D019353:Endemic Diseases; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D007896:Leishmaniasis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008103:Liver Cirrhosis / Q000150:complications / Q000175:diagnosis; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D010614:Pharynx / Q000473:pathology
D000666:Amphotericin B