title: Incidentally detected Meckel diverticulum: to resect or not to resect?
abstract: BACKGROUND
  Management of incidentally detected Meckel diverticulum (MD) remains controversial. Our aims were to establish: (1) the prevalence of MD; (2) the morbidity and (3) mortality due to MD.
  
  
  METHODS
  Systematic review: A total of 244 papers meeting defined criteria were included; there were no prospective or randomized studies. MD prevalence and mortality from autopsy studies, postoperative complications, and outcome of incidentally detected MD were extracted. Population-based data: Data were obtained from national databases on MD as cause of death, and on number of MD resections per year.
  
  
  RESULTS
  The prevalence of MD is 1.2% and historical mortality of MD was 0.01%. The current mortality from MD is 0.001%. The number of MD resections per year per 100,000 population decreased significantly after the pediatric age range (P < 0.001). Resection of incidentally detected MD has a significantly higher postoperative complication rate than leaving it in situ (P < 0.0001). The long-term outcome of patients with incidentally detected MD left in situ showed no complications. Seven-hundred fifty-eight patients would require incidentally detected MD resection to prevent 1 death from MD.
  
  
  CONCLUSIONS
  MD is present in 1.2% of the population, it is a very rare cause of mortality, and it is primarily a disease of the young. Leaving an incidentally detected MD in situ reduces the risk of postoperative complications without increasing late complications. A large number of MD resections would need to be performed to prevent 1 death from MD. The above evidence does not support the resection of incidentally detected MD.
authors.affiliation: Department of Pediatric Surgery, Institute of Child Health, London, England.
authors.forename: Augusto
authors.initials: A
authors.lastname: Zani
authors.forename: Simon
authors.initials: S
authors.lastname: Eaton
authors.forename: Clare M
authors.initials: CM
authors.lastname: Rees
authors.forename: Agostino
authors.initials: A
authors.lastname: Pierro
mesh_terms: D003657:Decision Making; D003937:Diagnosis, Differential; D004739:England / Q000453:epidemiology; D006801:Humans; D007813:Laparotomy / Q000379:methods*; D008467:Meckel Diverticulum / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D009017:Morbidity; D015996:Survival Rate