title: Cowpox infection transmitted from a domestic cat.
abstract: A 21-year-old immunocompetent woman developed a cowpox infec-tion,while working as a veterinarian's assistant in a rural area. She had never received vaccinia immunization and came in contact with a fatally-infected house cat. Under symptomatic treatment, the infection remained localized to one cheek and cleared over 3 weeks with substantial dermal-subcutaneous tissue destruction. Orthopoxvirus detection by PCR is a modern diagnostic standard, in addition to identification by negative-contrast electron microscopy. A promising therapeutic option is cidofovir, but this virostatic drug is not yet approved for the treatment of cowpox.
authors.affiliation: Department of Dermatology and Venereology, University of Magdeburg, Germany. bernd.bonnekoh@medizin.uni-magdeburg.de
authors.forename: Bernd
authors.initials: B
authors.lastname: Bonnekoh
authors.forename: Kristof
authors.initials: K
authors.lastname: Falk
authors.forename: Karl-Friedrich
authors.initials: KF
authors.lastname: Reckling
authors.forename: Susanne
authors.initials: S
authors.lastname: Kenklies
authors.forename: Andreas
authors.initials: A
authors.lastname: Nitsche
authors.forename: Beniam
authors.initials: B
authors.lastname: Ghebremedhin
authors.forename: Anna
authors.initials: A
authors.lastname: Pokrywka
authors.forename: Ingolf
authors.initials: I
authors.lastname: Franke
authors.forename: Bernd
authors.initials: B
authors.lastname: Thriene
authors.forename: Wolfgang
authors.initials: W
authors.lastname: König
authors.forename: Georg
authors.initials: G
authors.lastname: Pauli
authors.forename: Harald
authors.initials: H
authors.lastname: Gollnick
mesh_terms: D000328:Adult; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000635:transmission*; D002415:Cats; D015605:Cowpox / Q000175:diagnosis* / Q000635:transmission* / Q000662:veterinary; D005260:Female; D006801:Humans; D017193:Skin Diseases, Viral / Q000175:diagnosis* / Q000628:therapy / Q000635:transmission*