First time, low dose citalopram use-related serotonin syndrome.
Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-hydroxytryptamine, or 5-HT). Serotonin syndrome is a rarely observed side-effect of Citalopram use. This report discusses a case of first time, low dose citalopram use-related serotonin syndrome presenting with confusion, hyperhidrosis, hyperreflexia, myoclonus and fever.
Turedi
Suleyman
S
Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey. suleymanturedi@hotmail.com
Eraydin
Ismet
I
Gunduz
Abdulkadir
A
Kalkan
Asim
A
Hos
Ulku
U
D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage / Q000009:adverse effects*; D015283:Citalopram / Q000008:administration & dosage / Q000009:adverse effects*; D003221:Confusion / Q000139:chemically induced; D003533:Cyproheptadine / Q000627:therapeutic use; D005334:Fever / Q000139:chemically induced; D005440:Fluid Therapy; D006801:Humans; D006945:Hyperhidrosis / Q000139:chemically induced; D008297:Male; D009207:Myoclonus / Q000139:chemically induced; D012021:Reflex, Abnormal / Q000187:drug effects; D012702:Serotonin Antagonists / Q000627:therapeutic use; D020230:Serotonin Syndrome / Q000139:chemically induced* / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
D018687:Antidepressive Agents, Second-Generation; D015283:Citalopram; D003533:Cyproheptadine; D012702:Serotonin Antagonists; D017367:Selective Serotonin Reuptake Inhibitors