title: [Efficacy of dapsone in disseminated granuloma annulare: a case report and review of the literature\].
abstract: Granuloma annulare is a dermatosis of unknown cause that is generally self-limiting and has several clinical forms of presentation. It may be associated with pruritus or present asymptomatically. The disseminated variant of the disease accounts for 15 % of all cases. Most authors consider that the duration of this form is longer and that treatment response is worse than for localized forms. A range of therapeutic options have been tried for this disease with a wide range of outcomes. We present a patient with disseminated granuloma annulare who started treatment with dapsone after several therapeutic failures. With dapsone therapy, her cutaneous symptoms showed a clear improvement without any relevant side effects. We then review reports in the literature of cases of disseminated granuloma annulare treated with dapsone.
authors.affiliation: Servicio de Dermatología. Hospital Universitario Ramón y Cajal. Madrid. España. jestherichia@yahoo.es
authors.forename: E
authors.initials: E
authors.lastname: Martín-Sáez
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Guarino
authors.forename: R
authors.initials: R
authors.lastname: Carrillo-Gijón
authors.forename: E
authors.initials: E
authors.lastname: Muñoz-Zato
authors.forename: P
authors.initials: P
authors.lastname: Jaén-Olasolo
mesh_terms: D000368:Aged; D003622:Dapsone / Q000627:therapeutic use*; D005260:Female; D016460:Granuloma Annulare / Q000188:drug therapy*; D006801:Humans
chemical_list: D003622:Dapsone