title: [Anesthetic management of parturients with pre-eclampsia and eclampsia].
abstract: Preeclampsia is a pregnancy-associated illness affecting multiple organ systems. Symptoms typically occur after the 20th week of gestation and consist of hypertension (>140/90 mmHg) and proteinuria (>300 mg/day). It is one of the leading causes of premature birth worldwide and early diagnosis and treatment are essential for both fetal and maternal health. Therapy is aimed at lowering blood pressure sufficiently to prevent the most severe complications such as intracranial hemorrhages. At the same time attention must be paid to the possible untoward effects of blood pressure medications on uteroplacental perfusion and fetal well being. Magnesium is the cornerstone for both prevention and control of eclamptic cerebrovascular events. In cases of severe preeclampsia and eclampsia prompt delivery is indicated, often carried out by Cesarean section (>34 weeks of gestation). Compared to general anesthesia, regional anesthesia techniques offer certain advantages to both mother and fetus and in the absence of contraindications are the methods of choice.
authors.affiliation: Klinik für Anästhesiologie, Ludwig-Maximilians-Universität, Klinikum Innenstadt, München, Deutschland.
authors.forename: N I
authors.initials: NI
authors.lastname: Fetsch
authors.forename: D H
authors.initials: DH
authors.lastname: Bremerich
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D001241:Aspirin / Q000627:therapeutic use; D001810:Blood Volume / Q000502:physiology; D002585:Cesarean Section; D004461:Eclampsia / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D011247:Pregnancy
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin