HIV-1 hides an Achilles' heel in virion lipids.
In this issue, Sun et al. (2008) model the interface between a neutralizing antibody and HIV-1 glycoprotein 41 (gp41) envelope peptide in lipids. This model could help overcome a roadblock in HIV-1 vaccine development.
Haynes
Barton F
BF
Duke Human Vaccine Institute, Departments of Medicine, Pathology, and Immunology, Duke University School of Medicine, Durham, NC 27710, USA. hayne002@mc.duke.edu <hayne002@mc.duke.edu>
Alam
S Munir
SM
D000818:Animals; D015497:HIV-1 / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D008055:Lipids / Q000276:immunology*; D014771:Virion / Q000276:immunology* / Q000378:metabolism
D008055:Lipids