Aggressive angiomyxoma of supraclavicular fossa: a case report.
BACKGROUND
Aggressive angiomyxoma (AAM) is a rare myxoid mesenchymal tumor that occurs almost exclusively in the adult pelvic-perineal region and predominantly in females. Only 1 case of AAM occurring outside this region has been reported. Here we report another such case.


METHODS
The patient was referred for evaluation of a firm nonmovable mass of the supraclavicular fossa that had progressively enlarged within the previous year. MRI showed an infiltrative growth pattern with adhesion to adjacent anatomic structures. Wide excision was attempted, but a clear margin could not be achieved.


RESULTS
The histopathology revealed characteristic features of AAM, including stellate to spindle-shaped tumor cells set in a myxoid background, with hyalinizing thick-walled vessels and characteristic immunophenotype.


CONCLUSIONS
Accurate diagnosis and a definite surgical margin are crucial because AAM is locally aggressive and easily recurrent. Our case deserves attention because it shows that AAM may exist in the head and neck.
Pai
Chien-Yu
CY
Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
Nieh
Shin
S
Lee
Jih-Chin
JC
Lo
Chung-Ping
CP
Lee
Herng-Sheng
HS
D002968:Clavicle; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D011859:Radiography