title: MR-guided prostate interventions.
abstract: In this article the current issues of diagnosis and detection of prostate cancer are reviewed. The limitations for current techniques are highlighted and some possible solutions with MR imaging and MR-guided biopsy approaches are reviewed. There are several different biopsy approaches under investigation. These include transperineal open magnet approaches to closed-bore 1.5T transrectal biopsies. The imaging, image processing, and tracking methods are also discussed. In the arena of therapy, MR guidance has been used in conjunction with radiation methods, either brachytherapy or external delivery. The principles of the radiation treatment, the toxicities, and use of images are outlined. The future role of imaging and image-guided interventions lie with providing a noninvasive surrogate for cancer surveillance or monitoring treatment response. The shift to minimally invasive focal therapies has already begun and will be very exciting when MR-guided focused ultrasound surgery reaches its full potential.
authors.affiliation: Department of Radiology, Brigham & Women's Hospital, Boston, MA 02115, USA. ctempany@bwh.havard.edu
authors.forename: Clare
authors.initials: C
authors.lastname: Tempany
authors.forename: Sarah
authors.initials: S
authors.lastname: Straus
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Hata
authors.forename: Steven
authors.initials: S
authors.lastname: Haker
mesh_terms: D001706:Biopsy / Q000295:instrumentation / Q000379:methods; D001918:Brachytherapy / Q000379:methods; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000628:therapy; D018615:Ultrasonography, Doppler, Color / Q000379:methods