title: The MMP2 rs243865-T allele is not a major genetic factor for rheumatoid arthritis in the French Caucasian population.
abstract: The MMP2 rs243865-T allele was recently suggested to be associated with rheumatoid arthritis (RA) in a case-control study. MMP2 is a positional RA candidate gene. Our aim was to test rs243865 in a French family based study. No significant result was shown. The MMP2 rs243865-T allele is not a major rheumatoid arthritis genetic factor in this population.
authors.affiliation: GenHotel-EA3886, Evry-Paris VII Universities, Evry-Genopole Cedex, France. laurent@polyarthrite.net
authors.forename: L
authors.initials: L
authors.lastname: Jacq
authors.forename: V H
authors.initials: VH
authors.lastname: Teixeira
authors.forename: S
authors.initials: S
authors.lastname: Garnier
authors.forename: E
authors.initials: E
authors.lastname: Petit-Teixeira
authors.forename: F
authors.initials: F
authors.lastname: Cornélis
mesh_terms: D000483:Alleles; D001172:Arthritis, Rheumatoid / Q000235:genetics*; D005260:Female; D005602:France; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D020778:Matrix Metalloproteinase 2 / Q000235:genetics*; D044465:White People
chemical_list: C522361:MMP2 protein, human; D020778:Matrix Metalloproteinase 2