title: Coincidence of hepatocelluar carcinoma and hepatic angiomyolipomas in tuberous sclerosis complex: a case report.
abstract: Tuberous sclerosis complex (TSC) is a dominantly inherited disorder which characterized by the growth of harmatomatous in multiple organs. Unlike the common development of renal angiomyolipoma, hepatic angiomyolipoma rarely occur in patients with TSC. We report here a patient with hepatic angiomyolipomas and concurrent hepatocellular carcinoma in TSC. This represents the first reported case in English literature. In this patient, multiple hepatic angiomyolipomas were diagnosed with recognition of their fat components and typical clinical settings. Hepatocellular carcinoma in the left liver lobe was definitely diagnosed by US guided biopsy. In such clinical settings, fat containing lesions in liver can be reasonably treated as angiomyolipomas, but non fat containing lesions must be differentiated from hepatocellular carcinoma, imaging guided biopsy can be adopted to confirm the diagnosis.
authors.affiliation: Department of Radiology, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China. yb1974126@sina.com
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.forename: Wen-Hui
authors.initials: WH
authors.lastname: Chen
authors.forename: Pei-Zhi
authors.initials: PZ
authors.lastname: Shi
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Xiang
authors.forename: Ru-Jun
authors.initials: RJ
authors.lastname: Xu
authors.forename: Ji-Hong
authors.initials: JH
authors.lastname: Liu
mesh_terms: D018207:Angiomyolipoma / Q000000981:diagnostic imaging / Q000473:pathology*; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000000981:diagnostic imaging / Q000473:pathology*