title: Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin.
authors.affiliation: Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
authors.forename: Yushi
authors.initials: Y
authors.lastname: Futamura
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Sawa
authors.forename: Yoji
authors.initials: Y
authors.lastname: Umezawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Igarashi
authors.forename: Hikaru
authors.initials: H
authors.lastname: Nakamura
authors.forename: Kimiko
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Mikio
authors.initials: M
authors.lastname: Yamasaki
authors.forename: Etsu
authors.initials: E
authors.lastname: Tashiro
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Akamatsu
authors.forename: Masaya
authors.initials: M
authors.lastname: Imoto
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004317:Doxorubicin / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008968:Molecular Conformation; D012015:Reference Standards; D013302:Streptomyces / Q000187:drug effects*; D051020:bcl-X Protein / Q000037:antagonists & inhibitors* / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; C494811:BCL2L1 protein, human; D004187:Disaccharides; D007769:Lactams; D051020:bcl-X Protein; C527896:incednine; D004317:Doxorubicin