Disseminated histoplasmosis manifesting as a soft-tissue chest wall mass in a heart transplant recipient.
Soft-tissue masses are rarely associated with Histoplasma capsulatum infection. We describe a heart transplant patient who presented with a large right-sided chest wall mass as a manifestation of disseminated histoplasmosis. A successful clinical outcome was achieved upon recognition of the fungal pathogen.
Koo
H L
HL
Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA. koo@bcm.tmc.edu
Hamill
R J
RJ
Gentry
L O
LO
D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D003646:Debridement; D003937:Diagnosis, Differential; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006084:Graft Rejection / Q000517:prevention & control; D016027:Heart Transplantation / Q000009:adverse effects*; D006658:Histoplasma; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D018461:Soft Tissue Infections / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D016559:Tacrolimus / Q000008:administration & dosage; D035441:Thoracic Wall / Q000382:microbiology / Q000473:pathology; D014057:Tomography, X-Ray Computed; D019172:Transplantation Conditioning / Q000009:adverse effects*
D000935:Antifungal Agents; D007166:Immunosuppressive Agents; C068538:liposomal amphotericin B; D017964:Itraconazole; D000666:Amphotericin B; D009173:Mycophenolic Acid; D016559:Tacrolimus