Antiretroviral therapy in the Malawi defence force: access, treatment outcomes and impact on mortality.
BACKGROUND
HIV/AIDS affects all sectors of the population and the defence forces are not exempt. A national survey was conducted in all public and private sectors in Malawi that provide antiretroviral therapy (ART) to determine the uptake of ART by army personnel, their outcomes while on treatment, and the impact of ART on mortality in the Malawi Defence Force.


RESULTS
A retrospective cohort analysis was carried out, collecting data on access and retention on treatment from all 103 public and 38 private sector ART clinics in Malawi, using standardised patient master cards and clinic registers. Observations were censored on December 31(st) 2006. Independent data on mortality trends in army personnel from all causes between 2002 and 2006 were available from army records. By December 31(st) 2006, there were 85,168 patients ever started on ART in both public and private sectors, of whom 547 (0.7%) were army personnel. Of these, 22% started ART in WHO clinical stage 1 or 2 with a CD4-lymphocyte count of <or=250/mm(3) and 78% started in stage 3 or 4. Treatment outcomes of army personnel by December 31(st) 2006 were:-365 (67%) alive and on ART at their registration facility, 98 (18%) transferred out to another facility, 71 (13%) dead, 9 (2%) lost to follow-up, and 4 (<1%) stopped treatment. The probability of being alive on ART at 6-, 12- and 18-months was 89.8%, 83.4% and 78.8% respectively. All-cause mortality in army personnel declined dramatically over the five year period from 2002-2006.


CONCLUSIONS
There has been a good access of army personnel to ART during the last five years with excellent outcomes, and this should serve as an example for other defence forces and large companies in the region.
Banda
Alfred C
AC
Malawi Defence Force, Medical Department, Lilongwe, Malawi.
Makombe
Simon D
SD
Jahn
Andreas
A
Tweya
Hannock
H
Chuka
Stuart
S
Yu
Joseph Kwong-Leung
JK
Hedt
Bethany
B
Weigel
Ralf
R
Nkhata
Amon
A
Schouten
Erik J
EJ
Kamoto
Kelita
K
Harries
Anthony D
AD
D019380:Anti-HIV Agents / Q000600:supply & distribution / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008295:Malawi; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome
D019380:Anti-HIV Agents