Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA.
A DNAzyme-based label-free method for the colorimetric detection of DNA is introduced, with a supramolecular hemin-G-quartet complex as the sensing element and a 36-mer single-strand DNA as the analyte that is detected at 10 nM.
Li
Tao
T
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
Dong
Shaojun
S
Wang
Erkang
E
D052160:Benzothiazoles; D003124:Colorimetry / Q000379:methods; D004247:DNA / Q000032:analysis*; D021881:DNA, Catalytic / Q000737:chemistry*; D006147:Guanine / Q000737:chemistry; D006427:Hemin / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry; D010084:Oxidation-Reduction; D012680:Sensitivity and Specificity; D013451:Sulfonic Acids / Q000737:chemistry; D013844:Thiazoles / Q000737:chemistry; D013997:Time Factors
D052160:Benzothiazoles; D021881:DNA, Catalytic; D013451:Sulfonic Acids; D013844:Thiazoles; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D006147:Guanine; D006427:Hemin; D004247:DNA; D006861:Hydrogen Peroxide