title: Circumferential mucosal dissection and esophageal perforation in a patient with eosinophilic esophagitis.
abstract: A young man with a previous history of episodes of mild solid food dysphagia was admitted with a total dysphagia. The esophagogastroduodenoscopy (EGDS) showed an extensive disruption of mucosal layer with a cul-de-sac in the lower part of the esophagus. Soon after the procedure, the patient suffered from an acute chest pain and subsequent CT scan demonstrated an intramural circumferential dissection of thoracic esophagus, and a mediastinal emphysema. An emergency right thoracotomy was performed, followed by a total esophagectomy with esophagogastroplasty and jejunostomy. The histopathology confirmed that mucosal and submucosal layers were circumferentially detached from muscular wall and showed an eosinophilic infiltration of the whole organ with necrosis and erosions of mucosal, submucosal and muscular layers. The diagnosis was esophageal perforation in eosinophilic esophagitis.
authors.affiliation: Department of General and Thoracic Surgery, Cattinara Hospital, Strada di Fiume 447, Trieste 34149, Italy. g.liguori@fmc.units.it
authors.forename: Gennaro
authors.initials: G
authors.lastname: Liguori
authors.forename: Maurizio
authors.initials: M
authors.lastname: Cortale
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Cimino
authors.forename: Michele
authors.initials: M
authors.lastname: Sozzi
mesh_terms: D000328:Adult; D016145:Endoscopy, Digestive System / Q000009:adverse effects*; D004802:Eosinophilia / Q000473:pathology*; D004939:Esophageal Perforation / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D004941:Esophagitis / Q000473:pathology*; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000473:pathology