title: Pharmacological mydriasis secondary to ipratropium bromide: a cause of unilateral dilated pupil.
abstract: Ipratropium bromide is a commonly used bronchodilator which has been rarely reported to cause pharmacological mydriasis. We report a 22-year-old woman using 6-hourly nebulised ipratropium from a multi-dose preparation, who presented with a unilateral dilated pupil which resolved spontaneously over 24h after discontinuation of her ill-fitting nebuliser mask which had been directing the drug toward that eye. No alternative cause was found despite extensive investigations. Greater recognition of this iatrogenic cause of reversible pupillary dilatation may avoid the need for unnecessary investigations.
authors.affiliation: Sydney Eye Hospital, Sydney, Australia.
authors.forename: Neil S
authors.initials: NS
authors.lastname: Sharma
authors.forename: Ju-Lee
authors.initials: JL
authors.lastname: Ooi
authors.forename: Daya
authors.initials: D
authors.lastname: Papalkar
authors.forename: Shanel
authors.initials: S
authors.lastname: Sharma
authors.forename: Ian C
authors.initials: IC
authors.lastname: Francis
authors.forename: Victor S C
authors.initials: VS
authors.lastname: Fung
mesh_terms: D000328:Adult; D001993:Bronchodilator Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009241:Ipratropium / Q000009:adverse effects*; D015878:Mydriasis / Q000209:etiology*
chemical_list: D001993:Bronchodilator Agents; D009241:Ipratropium