title: Efficacy of Odiosoft-Rhino in assessment of nasal obstruction: a comparative study with acoustic rhinometry after treatment with budesonide nasal spray in patients with perennial allergic rhinitis.
abstract: BACKGROUND
  Odiosoft-Rhino (OR) is new software and equipment that can be used to measure changes in nasal obstruction after intranasal steroid treatment. OR is a promising method for measuring the degree of nasal obstruction. OR can precisely analyze nasal sound spectra in decibels, which is generated by nasal airflow. We studied the reliability of OR for assessing declining nasal obstruction after budesonide nasal spray treatment.
  
  
  METHODS
  Sixty-five patients with perennial allergic rhinitis (PAR) were enrolled in the study, and 52 of these patients completed the study. Nasal endoscopic examination, acoustic rhinometry (AR), and OR were performed and symptom scores were compared before and after 3 months of treatment with intranasal budesonide. All of the patients received 7 days of placebo treatment before receiving budesonide.
  
  
  RESULTS
  There was a significant difference in the visual analog scores of nasal obstruction and in the examination scores before and after the treatment for both the right and the left nasal cavities. Pretreatment AR findings and OR findings in the 2000- to 4000-Hz and 4000- to 6000-Hz intervals for both sides were significantly different from the posttreatment measurements (p = 0.000). Both AR and OR can assess the efficacy of budesonide nasal spray treatment for nasal obstruction in patients with PAR.
  
  
  CONCLUSIONS
  Both AR and OR are effective for assessing nasal obstruction and monitoring treatment efficacy but, as a simple and noninvasive test, OR can be used with confidence.
authors.affiliation: Department of Otorhinolaryngology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey. tahamiler@gmail.com
authors.forename: Rauf
authors.initials: R
authors.lastname: Tahamiler
authors.forename: Murat
authors.initials: M
authors.lastname: Yener
authors.forename: Salih
authors.initials: S
authors.lastname: Canakcioglu
mesh_terms: D000293:Adolescent; D000328:Adult; D019819:Budesonide / Q000008:administration & dosage*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000175:diagnosis*; D010147:Pain Measurement; D015203:Reproducibility of Results; D012221:Rhinitis, Allergic, Perennial; D023842:Rhinometry, Acoustic; D012680:Sensitivity and Specificity; D012984:Software
chemical_list: D005938:Glucocorticoids; D019819:Budesonide