title: [Adherence to treatment in patients with cystic fibrosis].
abstract: OBJECTIVE
  To evaluate the self-reported degree of adherence to treatment in patients with cystic fibrosis (CF), investigating associations with characteristics of the disease and with the degree of adherence perceived by health professionals.
  
  
  METHODS
  This was a prospective, cross-sectional study involving patients with CF monitored at a Program for Adults with CF. The degree of adherence was evaluated using a questionnaire. Patients were divided into two groups: greater degree of adherence and moderate/poor degree of adherence. Clinical data, Shwachman-Kulczycki clinical score, Brasfield radiographic score and spirometry data were obtained for all patients.
  
  
  RESULTS
  Out of 38 patients studied, 31 (81.6%) were classified as presenting a greater degree of adherence and 7 (18.4%) as presenting a moderate/poor degree of adherence. The self-reported patient adherence score correlated with the clinical score (r = -0.36, p = 0.028). The self-reported patient adherence score (median = 0.79) was higher than that perceived by health professionals (median = 0.71, p = 0.003). A greater degree of adherence was self-reported for respiratory therapy (by 84.2%), exercise (by 21.1%), prescribed diet (by 65.8%), pancreatic enzymes (by 96.3%), vitamins (by 79.4%), inhaled antibiotic therapy (by 76.7%) and inhaled DNase (by 79.4%).
  
  
  CONCLUSIONS
  Self-reported adherence of patients attending a Program for Adults with CF was good. The self-reported patient adherence score correlated inversely with the clinical score. Self-reported patient adherence was greater than the adherence perceived by health professionals.
authors.affiliation: Departamento de Medicina Interna, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. pdalcin@terra.com.br
authors.forename: Paulo de Tarso Roth
authors.initials: Pde T
authors.lastname: Dalcin
authors.forename: Greice
authors.initials: G
authors.lastname: Rampon
authors.forename: Lílian Rech
authors.initials: LR
authors.lastname: Pasin
authors.forename: Gretchem Mesquita
authors.initials: GM
authors.lastname: Ramon
authors.forename: Claudine Lacerda de Oliveira
authors.initials: CL
authors.lastname: Abrahão
authors.forename: Viviane Ziebell de
authors.initials: VZ
authors.lastname: Oliveira
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003550:Cystic Fibrosis / Q000523:psychology / Q000628:therapy*; D004032:Diet / Q000706:statistics & numerical data; D005081:Exercise Therapy / Q000706:statistics & numerical data; D005260:Female; D006282:Health Personnel / Q000523:psychology; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology; D010465:Perception; D011446:Prospective Studies; D013147:Spirometry; D018709:Statistics, Nonparametric