title: Heat production by skeletal muscles of rats and rabbits and utilization of glucose 6-phosphate as ATP regenerative system by rats and rabbits heart Ca2+-ATPase.
abstract: This report is divided in two parts. The first section shows that vesicles derived from the sarcoplasmic reticulum of rats skeletal muscle can cleave ATP at a faster rate and produce more heat that the vesicles derived from rabbit skeletal muscle. In the second part, we compared the rates of Ca(2+) transport and ATP hydrolysis by rats and rabbits heart sarcoplasmic reticulum. It is shown that the two vesicles preparations are able to use glucose 6-phosphate and hexokinase as an ATP regenerative system. The rates of Ca(2+)-uptake and ATP hydrolysis measured with glucose 6-phosphate and hexokinase is four to six times slower than that measured with phosphoenolpyruvate and pyruvate kinase as ATP regenerative system.
authors.affiliation: Instituto de Bioquímica Médica, Prédio do CCS, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, RJ 21941-590, Brazil.
authors.forename: Luisa Andrea
authors.initials: LA
authors.lastname: Ketzer
authors.forename: Leopoldo
authors.initials: L
authors.lastname: de Meis
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002478:Cells, Cultured; D004734:Energy Metabolism / Q000502:physiology*; D019298:Glucose-6-Phosphate / Q000378:metabolism*; D066298:In Vitro Techniques; D018482:Muscle, Skeletal / Q000502:physiology*; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D012519:Sarcoplasmic Reticulum / Q000502:physiology*; D022722:Thermogenesis / Q000502:physiology*
chemical_list: D019298:Glucose-6-Phosphate; D000255:Adenosine Triphosphate; D000252:Calcium-Transporting ATPases