title: Pathophysiology of diabetic nephropathy.
abstract: Diabetic nephropathy is the primary etiology of chronic kidney disease and kidney failure. With the incidence of type 2 diabetes rapidly increasing in the United States, it is imperative for health care professionals to clearly understand the mechanism of this condition and the implications for prevention. Early recognition of the diabetic state and tight serum glucose control can help prevent the consequence of diabetic nephropathy and its associated life-altering comorbidities.
authors.affiliation: Kansas City VA Medical Center, Kansas City, MO, USA.
authors.forename: Sherril
authors.initials: S
authors.lastname: Sego
mesh_terms: D017281:Cost of Illness; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D042241:Early Diagnosis; D005919:Glomerular Filtration Rate; D017127:Glycation End Products, Advanced / Q000502:physiology; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000209:etiology; D007677:Kidney Function Tests; D007678:Kidney Glomerulus / Q000503:physiopathology; D024802:Nurse's Role; D010349:Patient Compliance; D010353:Patient Education as Topic; D011322:Primary Prevention; D012079:Renal Circulation / Q000502:physiology; D017582:Renal Replacement Therapy; D014481:United States / Q000453:epidemiology
chemical_list: D017127:Glycation End Products, Advanced