title: Treatment of limb apraxia: moving forward to improved action.
abstract: Limb apraxia is a common disorder of skilled, purposive movement that is frequently associated with stroke and degenerative diseases such as Alzheimer disease. Despite evidence that several types of limb apraxia significantly impact functional abilities, surprisingly few studies have focused on development of treatment paradigms. Additionally, although the most disabling types of apraxia reflect damage to gesture and/or object memory systems, existing treatments have not fully taken advantage of principles of experience known to affect learning and neural plasticity. We review the current state of the art in the rehabilitation of limb apraxia, indicate possible points of contact with the learning literature, and generate suggestions for how translational principles might be applied to the development of future research on treatment of this disabling disorder.
authors.affiliation: Moss Rehabilitation Research Institute, Philadelphia, Pennsylvania 19141, USA.
authors.forename: Laurel J
authors.initials: LJ
authors.lastname: Buxbaum
authors.forename: Kathleen Y
authors.initials: KY
authors.lastname: Haaland
authors.forename: Mark
authors.initials: M
authors.lastname: Hallett
authors.forename: Lewis
authors.initials: L
authors.lastname: Wheaton
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Heilman
authors.forename: Amy
authors.initials: A
authors.lastname: Rodriguez
authors.forename: Leslie J
authors.initials: LJ
authors.lastname: Gonzalez Rothi
mesh_terms: D020240:Apraxia, Ideomotor / Q000188:drug therapy / Q000503:physiopathology* / Q000534:rehabilitation; D001072:Apraxias / Q000188:drug therapy / Q000503:physiopathology / Q000534:rehabilitation; D003071:Cognition; D003072:Cognition Disorders; D018450:Disease Progression; D006801:Humans; D009473:Neuronal Plasticity; D016896:Treatment Outcome