Teichoic acid glycosylation mediated by gtcA is required for phage adsorption and susceptibility of Listeria monocytogenes serotype 4b.
An insertion mutant of gtcA, responsible for serotype-specific glycosylation of the cell wall teichoic acid in serotype 4b strains of Listeria monocytogenes, was also resistant to both Listeria genus- and serotype 4b-specific phages. The sugar substituents on teichoic acid appeared essential for the adsorption of phages A500 (serotype 4b specific) and A511 (Listeria genus specific) to serotype 4b L. monocytogenes.
Cheng
Ying
Y
North Carolina State University, Department of Food Science, Raleigh, NC 27695-7624, USA.
Promadej
Nattawan
N
Kim
Jae-Won
JW
Kathariou
S
S
D001426:Bacterial Proteins / Q000378:metabolism*; D001435:Bacteriophages / Q000502:physiology*; D001482:Base Composition; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D006031:Glycosylation; D008089:Listeria monocytogenes / Q000378:metabolism / Q000821:virology*; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D013045:Species Specificity; D013682:Teichoic Acids / Q000378:metabolism*; D053586:Virus Internalization
D001426:Bacterial Proteins; D017931:DNA Primers; D013682:Teichoic Acids; C117102:gtcA protein, Listeria monocytogenes