[Effects of intratumoral injection therapy of dendritic cells combined with hyperthermia for cancer patients].
We proceeded with intratumoral injection therapy of dendritic cells (DC) in combination with hyperthermia for 41 cancer patients in the past two years. We confirmed a total of two CR cases (one of them already reported). We report two successful cases in this paper. Case 1: A uterine cervical cancer patient with metastases in cervical and abdominal lymphnodes was treated with intratumoral DC injection therapy combined with hyperthermia in cervical. She showed a CR not only in cervical but also in abdominal lymph nodes. Case 2: A sialyl grand cancer patient with metastases in cervical and axillary lymphnodes was treated with intratumoral DC injection therapy combined with hyperthermia in cervical. She showed a PR.
Takeda
Tsutomu
T
Osaka Cancer Immuno-Chemotherapy Center, Keisenkai.
Dong
Xianhui
X
Takeda
Hiroko
H
Haba
Akinao
A
Takeda
Yutaka
Y
D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood; D003713:Dendritic Cells / Q000276:immunology* / Q000637:transplantation*; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007167:Immunotherapy; D015552:Injections, Intralesional; D008207:Lymphatic Metastasis / Q000276:immunology / Q000473:pathology; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012468:Salivary Gland Neoplasms / Q000276:immunology* / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000473:pathology / Q000628:therapy*
D002272:Carcinoembryonic Antigen