Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents.
Improved LIPOCEST MRI contrast agents with highly shifted intraliposomal water protons were prepared by entrapping neutral polynuclear Tm(III)-based paramagnetic shift reagents in phospholipidic vesicles.
Terreno
Enzo
E
Department of Chemisry IFM and Molecular Imaging Center, University of Torino, Via P. Giuria 7, I-10125, Torino, Italy.
Barge
Alessandro
A
Beltrami
Lorena
L
Cravotto
Giancarlo
G
Castelli
Daniela Delli
DD
Fedeli
Franco
F
Jebasingh
Bhagavathsingh
B
Aime
Silvio
S
D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards*; D008280:Magnetics; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012015:Reference Standards; D013932:Thulium / Q000737:chemistry*
D003287:Contrast Media; D009942:Organometallic Compounds; D013932:Thulium