Palladium-catalyzed three-component arylcyanation of internal alkynes with aryl bromides and K4[Fe(CN)6].
The one-pot, palladium-catalyzed, three-component coupling of aryl bromides, internal alkynes, and environmentally friendly K4[Fe(CN)6] provides an efficient and direct method for the preparation of beta-arylalkenylnitriles.
Cheng
Yi-nan
YN
Chemistry Department, Key Lab of Chemical Biology and Organic Chemistry of Henan Province, Zhengzhou University, Zhengzhou 450052, P.R. China.
Duan
Zheng
Z
Yu
Liujian
L
Li
Zhongxian
Z
Zhu
Yu
Y
Wu
Yangjie
Y
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
D000480:Alkynes; D006842:Hydrocarbons, Brominated; D009570:Nitriles; D010165:Palladium