title: Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth.
abstract: OBJECTIVE
  The objective of this study was to investigate the association among adiposity, insulin resistance, and inflammatory markers [high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-alpha] and adiponectin and to study the effects of exercise training on adiposity, insulin resistance, and inflammatory markers among obese male Korean adolescents.
  
  
  METHODS
  Twenty-six obese and 14 lean age-matched male adolescents were studied. We divided the obese subjects into two groups: obese exercise group (N = 14) and obese control group (N = 12). The obese exercise group underwent 6 weeks of jump rope exercise training (40 min/d, 5 d/wk). Adiposity, insulin resistance, lipid profile, hs-CRP, IL-6, TNF-alpha, and adiponectin were measured before and after the completion of exercise training.
  
  
  RESULTS
  The current study demonstrated higher insulin resistance, total cholesterol, LDL-C levels, triglyceride, and inflammatory markers and lower adiponectin and HDL-C in obese Korean male adolescents. Six weeks of increased physical activity improved body composition, insulin sensitivity, and adiponectin levels in obese Korean male adolescents without changes in TNF-alpha, IL-6, and hs-CRP.
  
  
  CONCLUSIONS
  Obese Korean male adolescents showed reduced adiponectin levels and increased inflammatory cytokines. Six weeks of jump rope exercise improved triglyceride and insulin sensitivity and increased adiponectin levels.
authors.affiliation: Department of Sport and Leisure Studies, Yonsei University, Seodaemun-Gu Shinchon-Dong 134, Seoul, Korea.
authors.forename: Eun Sung
authors.initials: ES
authors.lastname: Kim
authors.forename: Jee-Aee
authors.initials: JA
authors.lastname: Im
authors.forename: Kyoung Chul
authors.initials: KC
authors.lastname: Kim
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Park
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Suh
authors.forename: Eun Seok
authors.initials: ES
authors.lastname: Kang
authors.forename: So Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Yoonsuk
authors.initials: Y
authors.lastname: Jekal
authors.forename: Chul Won
authors.initials: CW
authors.lastname: Lee
authors.forename: Yong-Jin
authors.initials: YJ
authors.lastname: Yoon
authors.forename: Hyun Chul
authors.initials: HC
authors.lastname: Lee
authors.forename: Justin Y
authors.initials: JY
authors.lastname: Jeon
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D002097:C-Reactive Protein / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D015850:Interleukin-6 / Q000097:blood; D007723:Korea; D008297:Male; D009765:Obesity / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D014280:Triglycerides / Q000097:blood; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D052242:Adiponectin; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015850:Interleukin-6; D014280:Triglycerides; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein