[Hepatic resections for hepatocarcinoma in the XXI century].
Hepatic resection is today the treatment of choice for cirrhotic patients affected by hepatocellular carcinoma (HCC). Short term results are now definitely satisfactory, with a mortality rate in the referral centers lower than 5%. However, long term results are affected by a high recurrence rate, between 50% and 100%, due to the underlying cirrhosis. Notwithstanding the high recurrence rate, the hepatic resection guarantees a five years survival between 40% and 60%, comparable to the one offered by liver transplantation. The aim of this paper is to review the results of studies on resected cirrhotic patients affected by HCC.
Ramacciato
G
G
UOC Chirurgia Epatobiliopancreatica, Ospedale S. Andrea, Facoltà di Medicina e Chirurgia, Università degli Studi di Roma La Sapienza II, Roma, Italy. giovanni.ramacciato@uniroma1.it
Mercantini
P
P
Nigri
G
G
Giaccaglia
V
V
Dente
M
M
Del Gaudio
M
M
Lauro
A
A
Ercolani
G
G
Pinna
A D
AD
D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000601:surgery*; D018572:Disease-Free Survival; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008103:Liver Cirrhosis / Q000150:complications; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome