Treatment of limb apraxia: moving forward to improved action.
Limb apraxia is a common disorder of skilled, purposive movement that is frequently associated with stroke and degenerative diseases such as Alzheimer disease. Despite evidence that several types of limb apraxia significantly impact functional abilities, surprisingly few studies have focused on development of treatment paradigms. Additionally, although the most disabling types of apraxia reflect damage to gesture and/or object memory systems, existing treatments have not fully taken advantage of principles of experience known to affect learning and neural plasticity. We review the current state of the art in the rehabilitation of limb apraxia, indicate possible points of contact with the learning literature, and generate suggestions for how translational principles might be applied to the development of future research on treatment of this disabling disorder.
Buxbaum
Laurel J
LJ
Moss Rehabilitation Research Institute, Philadelphia, Pennsylvania 19141, USA.
Haaland
Kathleen Y
KY
Hallett
Mark
M
Wheaton
Lewis
L
Heilman
Kenneth M
KM
Rodriguez
Amy
A
Gonzalez Rothi
Leslie J
LJ
D020240:Apraxia, Ideomotor / Q000188:drug therapy / Q000503:physiopathology* / Q000534:rehabilitation; D001072:Apraxias / Q000188:drug therapy / Q000503:physiopathology / Q000534:rehabilitation; D003071:Cognition; D003072:Cognition Disorders; D018450:Disease Progression; D006801:Humans; D009473:Neuronal Plasticity; D016896:Treatment Outcome