title: [Effects of garlic allicor tablets on lipid metabolism and risk of fatal cardiovascular complications in patients with atherogenic dyslipoproteinemia].
abstract: The aim of investigation was to assess an effect of allicor at a lipid metabolism and a free radical oxidation of blood lipids, anthropometic values, and arterial blood pressure at patients with atherogenic dislipoproteidemy. 112 patients (47 men and 65 women) 40 to 60 years of age were examined. 56 patients had ischemic heart disease and/or equal disorders. Another 56 patients were free of any signs of atherosclerosis, but had one or more risk factor of cardiovascular pathology. Six month therapy using allicor results in moderate hypolipidemic and antioxidative effect. A dosage of 600 mg per day decreases individual ten-year chance of fatal cardiovascular complications at patients with clinical signs of atherosclerosis, whereas at patients who have no signs of atherosclerosis the complications are decreased with dosage of 300 mg per day.
authors.forename: N I
authors.initials: NI
authors.lastname: Gromnatskiĭ
authors.forename: Zh E
authors.initials: ZhE
authors.lastname: Sereditskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Lazareva
authors.forename: A V
authors.initials: AV
authors.lastname: Sereditskiĭ
authors.forename: G V
authors.initials: GV
authors.lastname: Annenkova
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D018752:Diet, Fat-Restricted; D004305:Dose-Response Relationship, Drug; D050171:Dyslipidemias / Q000150:complications / Q000178:diet therapy / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D005737:Garlic; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D028321:Plant Preparations / Q000627:therapeutic use*; D011379:Prognosis; D018570:Risk Assessment; D012737:Sex Factors; D013607:Tablets
chemical_list: D008055:Lipids; D028321:Plant Preparations; D013607:Tablets