Primary versus nonprimary cytomegalovirus infection during pregnancy, Israel.
We examined prospectively the outcome of primary and nonprimary maternal cytomegalovirus (CMV) infection during pregnancy among 88 and 120 women, respectively. The risk for vertical transmission was 1.83x higher for primary infection than for nonprimary infection. Nonetheless, congenital CMV disease was diagnosed in both infection groups at similar rates.
Rahav
Galia
G
Hadassah Medical Center-Hebrew University School of Medicine, Jerusalem, Israel. galia.rahav@sheba.health.gov.il
Gabbay
Rinat
R
Ornoy
Asher
A
Shechtman
Svetlana
S
Arnon
Judith
J
Diav-Citrin
Orna
O
D000649:Amniocentesis; D015331:Cohort Studies; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000000981:diagnostic imaging / Q000276:immunology / Q000635:transmission / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D018445:Infectious Disease Transmission, Vertical; D007557:Israel; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000821:virology*; D011256:Pregnancy Outcome; D011446:Prospective Studies; D014463:Ultrasonography
D007074:Immunoglobulin G; D007075:Immunoglobulin M