title: Use of Cortoss as an alternative material in calvarial defects: the first clinical results in cranioplasty.
abstract: A clinical series of 13 patients who underwent cranioplasty using a new quick setting material, namely Cortoss, was done over 3-year period. Thus, the primary objective of this study is to evaluate the role of Cortoss in the treatment calvarial defects which were mainly due to trauma (4 patients), tumor or tumor-like lesions (5 patients), middle cerebral infarction (3 patients), and gun shot wound (1 patient). The surgical technique was found to be simple and effective. Long-term follow-up (mean 24.3 months) demonstrated satisfactory results in terms of surgical (functional) and cosmetic outcomes. None of the patients developed complications including infections, foreign body reactions or material leakage. The results led us to suggest that the use of Cortoss in the case of calvarial defects seems to be safe, effective, quick, and a feasible method for cranioplasty. We conclude that the mechanical, immunologic, and technical-grafting properties of Cortoss, together with its superior esthetic and psychological effects, probably will make it the best material for cranioplasty.
authors.affiliation: Department of Neurosurgery, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Galip Zihni
authors.initials: GZ
authors.lastname: Sanus
authors.forename: Taner
authors.initials: T
authors.lastname: Tanriverdi
authors.forename: Mustafa Onur
authors.initials: MO
authors.lastname: Ulu
authors.forename: Ali Metin
authors.initials: AM
authors.lastname: Kafadar
authors.forename: Necmettin
authors.initials: N
authors.lastname: Tanriover
authors.forename: Fatma
authors.initials: F
authors.lastname: Ozlen
mesh_terms: D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use*; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use*; D018786:Bone Substitutes / Q000627:therapeutic use*; D003399:Craniotomy / Q000379:methods; D004954:Esthetics; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000601:surgery; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D012449:Safety; D012886:Skull / Q000293:injuries / Q000601:surgery*; D012887:Skull Fractures / Q000601:surgery; D012888:Skull Neoplasms / Q000601:surgery; D016896:Treatment Outcome; D014948:Wounds, Gunshot / Q000601:surgery
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; C475778:CORTOSS; D017438:Bisphenol A-Glycidyl Methacrylate