title: Foreign-body granulomas in the trunk and extremities may simulate malignant soft-tissue tumors: report of three cases.
abstract: Three cases of foreign-body granulomas arising from soft tissues of the extremities or trunk are reported. All patients had a history of having undergone surgery 19 to 35 years ago. It was difficult to distinguish these granulomas from malignant soft-tissue tumors preoperatively by magnetic resonance (MR) images, as the tumors were over 10 cm in diameter and degenerated foreign bodies could not be detected on MR images. Finally, a histological diagnosis of foreign-body granuloma was made by preoperative or intraoperative biopsy in all cases. A palpable tumor adjacent to a previous surgery scar is therefore a warning that it might represent a granuloma, in spite of various image findings.
authors.affiliation: Department of Orthopedic Surgery, Mie University Faculty of Medicine, Tsu, Mie, Japan. tomoki66@clin.medic.mie-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Kusuzaki
authors.forename: T
authors.initials: T
authors.lastname: Matsubara
authors.forename: A
authors.initials: A
authors.lastname: Matsumine
authors.forename: A
authors.initials: A
authors.lastname: Uchida
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002081:Buttocks / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005121:Extremities / Q000473:pathology*; D019786:Gadolinium DTPA; D015745:Granuloma, Foreign-Body / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*; D013848:Thigh / Q000473:pathology; D013995:Time
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA