Specific detection of cysteine and homocysteine: recognizing one-methylene difference using fluorosurfactant-capped gold nanoparticles.
Aggregation of fluorosurfactant-capped gold nanoparticles could be induced selectively by cysteine and homocysteine and, when solution ionic strength was low, the kinetics of homocysteine-induced aggregation of large size nanoparticles (approximately 40 nm) was much faster than that induced by cysteine, leading to specific detection of homocysteine in the presence of excess cysteine.
Lu
Chao
C
Department of Chemistry, The University of Hong Kong, Pokfulam, Hong Kong, China.
Zu
Yanbing
Y
D003545:Cysteine / Q000032:analysis / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006710:Homocysteine / Q000032:analysis / Q000737:chemistry*; D006860:Hydrogen Bonding; D007700:Kinetics; D053758:Nanoparticles / Q000737:chemistry*; D009994:Osmolar Concentration; D012965:Sodium Chloride / Q000737:chemistry; D012996:Solutions / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry*; D013997:Time Factors
D012996:Solutions; D013501:Surface-Active Agents; D006710:Homocysteine; D012965:Sodium Chloride; D006046:Gold; D003545:Cysteine