title: Ruptured cerebral aneurysm and acute coronary artery dissection in the setting of multivascular fibromuscular dysplasia: a case report.
abstract: Fibromuscular dysplasia (FMD) is a segmental noninflammatory nonatherosclerotic vascular disease that has been described in almost every arterial bed, including the cerebral and coronary arteries. FMD of cerebral vessels has been associated with development of saccular aneurysms in the involved vessels. Acute dissection of coronary arteries is also a rare complication of FMD. Herein, we report the first case of both complications of FMD occurring in a single patient-a ruptured anterior communicating artery aneurysm and a right coronary artery dissection occurring in a 38-year-old woman. At autopsy, FMD was found in multiple vascular beds. Our findings reveal the potential for involvement of several vascular beds in patients with FMD, resulting in multiple vascular complications.
authors.affiliation: Department of Pathology, New York Medical College, NY, USA. sergey_brodsky@nymc.edu
authors.forename: Sergey V
authors.initials: SV
authors.lastname: Brodsky
authors.forename: Gita
authors.initials: G
authors.lastname: Ramaswamy
authors.forename: Praveen
authors.initials: P
authors.lastname: Chander
authors.forename: Alex
authors.initials: A
authors.lastname: Braun
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000209:etiology* / Q000473:pathology; D017542:Aneurysm, Ruptured / Q000209:etiology* / Q000473:pathology; D001344:Autopsy; D003323:Coronary Aneurysm / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000473:pathology; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology* / Q000473:pathology