title: New-onset seizures: a possible association with clonidine?
abstract: Clonidine is used as second-line medication for the treatment of attention deficit hyperactivity disorder in children. Product information concerning clonidine reported seizures only after overdosage of clonidine, and the prescription of clonidine has not been contraindicated in patients with known epilepsy. The present case report discusses a possible association of clonidine with new-onset seizures, in the context of status epilepticus in a 9-year-old girl.
authors.affiliation: Youth Health Care Division, Regional Public Health Institute Maastricht, Department of Child Neurology, University Hospital Maastricht, The Netherlands. frans.feron@ggdzl.nl
authors.forename: Frans J M
authors.initials: FJ
authors.lastname: Feron
authors.forename: Jos G M
authors.initials: JG
authors.lastname: Hendriksen
authors.forename: Joost
authors.initials: J
authors.lastname: Nicolai
authors.forename: Johan S H
authors.initials: JS
authors.lastname: Vles
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000188:drug therapy / Q000209:etiology; D002547:Cerebral Palsy / Q000150:complications; D002648:Child; D003000:Clonidine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D012640:Seizures / Q000139:chemically induced* / Q000188:drug therapy; D013226:Status Epilepticus / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D000316:Adrenergic alpha-Agonists; D000927:Anticonvulsants; D003000:Clonidine