title: Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome.
abstract: OBJECTIVE
  Assessment of patient-related factors contributing (1) to tooth loss and (2) to the quality of treatment outcome 10 years after initiation of anti-infective therapy.
  
  
  METHODS
  All patients who had received active periodontal treatment 10 years ago by the same examiner were recruited consecutively until a total of 100 patients were re-examined. Re-examination was performed by a second examiner and included clinical examination, test for interleukin-1 (IL-1) polymorphism, smoking history, review of patients' files (e.g. regularity of supportive periodontal therapy: SPT). Statistical analysis included Poisson and logistic regressions.
  
  
  RESULTS
  Fifty-three patients attended SPT regularly, 59 were females, 38 were IL-1 positive. Poisson regressions identified mean plaque index during SPT (p<0.0001), irregular attendance of SPT (p<0.0001), age (p<0.0001), initial diagnosis (p=0.0005), IL-1 polymorphism (p=0.0007), smoking (p=0.0053), and sex (p=0.0487) as factors significantly contributing to tooth loss. Additionally, mean plaque index during SPT (p=0.011) and irregular SPT (p=0.002) were associated with a worse periodontal status 10 years after initiation of therapy.
  
  
  CONCLUSIONS
  The following risk factors for tooth loss were identified: ineffective oral hygiene, irregular SPT, IL-1 polymorphism, initial diagnosis, smoking, age and sex.
authors.affiliation: Department of Periodontology, Center of Dental, Oral, and Maxillofacial Medicine (Carolinum), Hospital of the Johann Wolfgang Goethe-University Frankfurt/Main, Frankfurt, Germany. eickholz@med.uni-frankfurt.de
authors.forename: Peter
authors.initials: P
authors.lastname: Eickholz
authors.forename: Jens
authors.initials: J
authors.lastname: Kaltschmitt
authors.forename: Janet
authors.initials: J
authors.lastname: Berbig
authors.forename: Peter
authors.initials: P
authors.lastname: Reitmeir
authors.forename: Bernadette
authors.initials: B
authors.lastname: Pretzl
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D016301:Alveolar Bone Loss / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000235:genetics*; D008297:Male; D008336:Mandibular Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D008439:Maxillary Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D008875:Middle Aged; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D011110:Polymorphism, Genetic / Q000235:genetics*; D011859:Radiography; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D016388:Tooth Loss / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000235:genetics; D016896:Treatment Outcome
chemical_list: D007375:Interleukin-1