R protein activation: another player revealed.
Resistance proteins play an integral role in plant innate immunity by perceiving pathogens and triggering defense responses. In this issue of Cell Host & Microbe, Kang et al. uncover CRT1, an ATPase essential for resistance to turnip crinkle virus in Arabidopsis mediated by the Resistance (R) protein HRT. CRT1 interacts with an array of R proteins in vivo, suggesting that it plays a role in R protein activation.
Monaghan
Jacqueline
J
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Li
Xin
X
D000251:Adenosine Triphosphatases / Q000235:genetics / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism / Q000821:virology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D019184:Carmovirus / Q000472:pathogenicity*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism*
D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; C491954:HRT protein, Arabidopsis; D012097:Repressor Proteins; D000251:Adenosine Triphosphatases