title: THA using metal-on-metal articulation in active patients younger than 50 years.
abstract: The main concern of patients with longer life expectancies and of patients who are younger and more active is the longevity of their total hip arthroplasty. We retrospectively reviewed 83 cementless total hip arthroplasties in 73 patients implanted with metal-on-metal articulation. All patients were younger than 50 years old (average age, 41 years) at the time of the index procedure, and 80% of the patients had an activity level graded 4 or 5 when measured with the system of Devane et al. A 28-mm Metasul articulation was used with three different cementless titanium acetabular components. At the most recent followup (average, 7.3 years), the average Merle d'Aubigné-Postel score improved from a preoperative 11.1 points to 17.4 points. We observed no radiographic evidence of component loosening. Ten acetabular components had lucency limited to one zone. The 10-year survivorship with the end point of revision (ie, exchange of at least one prosthetic or bearing component) was 100% (95% confidence interval, 90%-100%). Metasul bearings with cementless acetabular components remain promising in this high-risk younger patient population. However, additional followup strategies are recommended to determine any possible long-term deleterious effects associated with the dissemination of metallic ions.
  
  
  METHODS
  Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
authors.affiliation: Department of Orthopaedic Surgery, Clinique de l'Yvette, 67-71 route de Corbeil, 91160 Longjumeau, France. c.delaunay@clinique-yvette.com
authors.forename: Christian P
authors.initials: CP
authors.lastname: Delaunay
authors.forename: François
authors.initials: F
authors.lastname: Bonnomet
authors.forename: Philippe
authors.initials: P
authors.lastname: Clavert
authors.forename: Philippe
authors.initials: P
authors.lastname: Laffargue
authors.forename: Henri
authors.initials: H
authors.lastname: Migaud
mesh_terms: D000077:Acetabulum / Q000601:surgery; D000328:Adult; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging / Q000601:surgery*; D011475:Prosthesis Failure; D011859:Radiography; D012189:Retrospective Studies; D014025:Titanium; D016896:Treatment Outcome
chemical_list: D014025:Titanium