title: Versatile and expeditious synthesis of aurones via Au I-catalyzed cyclization.
abstract: Aurones are conveniently formed in a three-step procedure including a goldI-catalyzed cyclization of 2-(1-hydroxyprop-2-ynyl)phenols as a highly regio- and stereoselective key step. A wide diversity of derivatives can be obtained starting from substituted salicylaldehydes. Synthesis of natural 4,6,3',4'-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4'-chloroaurone) were achieved.
authors.affiliation: Laboratoire de Synthèse et Réactivité Organique, associé au CNRS, Institut de Chimie, Université Louis Pasteur, 4 rue Blaise Pascal, 67000 Strasbourg, France.
authors.forename: Hassina
authors.initials: H
authors.lastname: Harkat
authors.forename: Aurélien
authors.initials: A
authors.lastname: Blanc
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Weibel
authors.forename: Patrick
authors.initials: P
authors.lastname: Pale
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis*; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D001572:Benzofurans; C486837:aurone; D006046:Gold