[Long latency auditory evoked potentials in adults with HIV/Aids].
BACKGROUND
Long Latency Auditory Evoked Potentials.


OBJECTIVE
to characterize the Long Latency Auditory Evoked Potentials (LLAEP) in individuals with HIV/AIDS in comparison to a control group.


METHODS
the research sample was composed by 21 individuals with HIV/AIDS - research group (14 male and 7 female), with ages ranging from 31 to 48 years, and 21 healthy individuals - control group (5 male and 16 female), with ages ranging from 19 to 36 years. The latency and amplitude values of the P300 wave were analyzed; latency of N1 and P2 waves, and amplitude N1-P2. The electrodes were placed on the following positions: A1, A2, Cz and Fpz.


RESULTS
the T-student test was used to analyze the results and the adopted significance level was of 5%. In the analyzes of P300 it was observed that the group with HIV/AIDS presented greater latency values (p-value = 0,010) and lower amplitude values (p-value = 0,021) when compared to the control group. The analysis of the N1-P2 complex revealed that the research group presented higher latency values for both, N1 wave (p-value = 0,035) and P2 wave, however for this last one, there was no significant statistical difference when compared to the control group. Concerning the amplitude analysis of the N1-P2 complex, it was verified that the control group presented significantly higher values when compared to the research group.


CONCLUSIONS
the findings of this study indicates that individuals with HIV/AIDS present alterations in the Long Latency Auditory Evoked Potentials (higher latencies and lower amplitudes of N1, P2 and P300 waves), suggesting a disorder in the cortical regions of the auditory pathway, and therefore stressing the importance of such tests in the evaluation of these individuals.
Silva
Aline Covo da
AC
Faculdade de Medicina, Universidade de São Paulo, São Paulo. aline.covo@uol.com.br
Pinto
Fernanda Rodrigues
FR
Matas
Carla Gentile
CG
D000161:Acoustic Stimulation; D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology; D000328:Adult; D001304:Auditory Diseases, Central / Q000150:complications / Q000175:diagnosis*; D016022:Case-Control Studies; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time