Development of the human cerebral cortex: Boulder Committee revisited.
In 1970 the Boulder Committee described the basic principles of the development of the CNS, derived from observations on the human embryonic cerebrum. Since then, numerous studies have significantly advanced our knowledge of the timing, sequence and complexity of developmental events, and revealed important inter-species differences. We review current data on the development of the human cerebral cortex and update the classical model of how the structure that makes us human is formed.
Bystron
Irina
I
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, OX1 3PT, UK. irina.bystron@dpag.ox.ac.uk
Blakemore
Colin
C
Rakic
Pasko
P
D000818:Animals; D019521:Body Patterning / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology*; D019070:Cell Lineage / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology; D002540:Cerebral Cortex / Q000166:cytology* / Q000196:embryology* / Q000502:physiology; D006801:Humans; D009434:Neural Pathways / Q000166:cytology / Q000196:embryology / Q000502:physiology; D009457:Neuroglia / Q000166:cytology* / Q000378:metabolism; D009474:Neurons / Q000166:cytology* / Q000378:metabolism; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism