title: Acute management of poor condition subarachnoid hemorrhage patients.
abstract: Poor condition subarachnoid hemorrhage (SAH) patients present a high mortality and morbidity. In this study, we reviewed the acute interventional (surgical and endovascular) management of 109 SAH-poor condition patients, who were treated as early as logistically possible after confirming stable circulation parameters. Patients over the age of 70 years, without clinical response to painful stimulation were excluded. We recognized at least 3 different postinterventional therapeutic approaches: (1) Norm- or hypovolemic, normotensive hemodilution in 30 patients with space-occupying intracranial hematomas as well as in 31 cases with acute cerebro-spinal-fluid obstruction. (2) Normovolemic, hypertensive hemodilution after unilateral decompressive craniotomy in 23 surgical- and 2 endovascular-treated patients with focalized space occupying lesions and reduced cerebral perfusion. (3) Hypovolemic, normo-, or hypertensive hemodilution after bilateral decompressive craniotomy in 23 cases with massive brain-swelling. We observed a reduced mortality (21%). The overall late outcome was favorable in 56% and unfavorable in 23%. Selective aggressive treatment adapted to increase the cerebral perfusion, seems to be an effective therapy to improve the survival and outcome of several poor condition SAH-patients.
authors.affiliation: Department of Neurosurgery, Städtische Kliniken Frankfurt-Höchst, Frankfurt am Main, Germany.
authors.forename: Archavlis
authors.initials: A
authors.lastname: Eleftherios
authors.forename: Mario Nazareno
authors.initials: MN
authors.lastname: Carvi y Nievas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D001929:Brain Edema / Q000628:therapy; D002560:Cerebrovascular Circulation; D002648:Child; D003399:Craniotomy; D003422:Critical Care; D019299:Decompression, Surgical; D004621:Embolization, Therapeutic; D005260:Female; D006438:Hemodilution / Q000379:methods; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013345:Subarachnoid Hemorrhage / Q000401:mortality / Q000628:therapy*; D013525:Surgical Instruments