title: Treatment outcome in endodontics: the Toronto study--phases 3 and 4: orthograde retreatment.
abstract: Outcome 4-6 years after retreatment was assessed for Phases 3 and 4 of the Toronto Study. Of 477 teeth retreated, 333 were lost to follow-up, 18 were extracted, and 126 (41% recall, excluding 124 discontinuers) were examined for outcome of healed (periapical index score, < or = 2; no signs or symptoms) or diseased. When pooled with Phases 1 and 2, 187 of 229 teeth (82%) were healed. Logistic regression identified significant (P < or = .05) preoperative outcome predictors: root filling quality (odds ratio [OR], 4.18; confidence interval [CI], 1.72-10.12; healed: inadequate, 88%; adequate, 66%), perforation (OR, 4.01; CI, 1.28-12.62; healed: absent, 87%; present, 56%), and radiolucency (OR, 3.33; CI, 1.19-9.36; healed: absent, 93%; present, 80%). In teeth with radiolucency, outcome predictors were number of treatment sessions (OR, 12.08; CI, 1.84-infinity; healed: one, 100%; > or = 2, 77%) and previous root filling quality (OR, 7.68; CI, 2.36-26.89; healed: inadequate, 86%; adequate, 50%). Outcome was better in teeth with inadequate previous root filling, without perforation and radiolucency. Suggested significance of number of treatment sessions in teeth with radiolucency requires validation from randomized controlled trials.
authors.affiliation: Discipline of Endodontics, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Cristian
authors.initials: C
authors.lastname: de Chevigny
authors.forename: Thuan T
authors.initials: TT
authors.lastname: Dao
authors.forename: Bettina R
authors.initials: BR
authors.lastname: Basrani
authors.forename: Vincent
authors.initials: V
authors.lastname: Marquis
authors.forename: Mahsa
authors.initials: M
authors.lastname: Farzaneh
authors.forename: Sarah
authors.initials: S
authors.lastname: Abitbol
authors.forename: Shimon
authors.initials: S
authors.lastname: Friedman
mesh_terms: D015331:Cohort Studies; D003442:Crowns / Q000706:statistics & numerical data; D003786:Dental Pulp Cavity / Q000000981:diagnostic imaging / Q000293:injuries; D003793:Dental Restoration, Permanent / Q000706:statistics & numerical data; D003794:Dental Restoration, Temporary / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario; D010485:Periapical Periodontitis / Q000145:classification / Q000000981:diagnostic imaging / Q000628:therapy; D011176:Post and Core Technique / Q000706:statistics & numerical data; D011859:Radiography; D019233:Retreatment; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D012389:Root Canal Obturation / Q000592:standards / Q000706:statistics & numerical data; D018915:Root Canal Preparation / Q000592:standards / Q000706:statistics & numerical data; D012390:Root Canal Therapy / Q000592:standards* / Q000706:statistics & numerical data; D014081:Tooth Extraction / Q000706:statistics & numerical data; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology
chemical_list: D012387:Root Canal Filling Materials