[Epilepsy surgery; indication and the latest treatment].
In order to obtain the optimal results (being free from seizures and functional deficits) in epilepsy surgery from the viewpoint of restorative functional neurology, it is essential to define both epileptogenic and functional zones precisely. Several important concerns are listed as follows for neurologists who care and introduce surgical candidates with intractable epilepsy from their clinic to the epilepsy surgery centers; 1) intractability of seizures, 2) decreased verbal memory after surgery in patients with left mesial temporal lobe epilepsy, 3) surgical outcome of patients with neocortical epilepsy without MRI abnormalities, 4) possible dissociation between ictal onset zone and ictal semiology, and 5) interventional neurophysiology which enhances endogenous inhibitory networks in the brain in an externally triggered or internally driven way.
Ikeda
Akio
A
Department of Neurology, Kyoto University School of Medicine.
D004827:Epilepsy / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging