title: [Role of epidermal growth factor and its receptor family in ocular surface wound healing].
abstract: The epidermal growth factor (EGF) and its receptor (ErbB) family have been shown to be involved in cell differentiation, proliferation and migration. EGF family members are expressed in the tear constantly and ErbB is expressed in ocular surface tissues. EGFR activation and subsequent intracellular signaling are required for corneal wound healing. They are important for the maintenance of the integrity of the ocular surface. The purpose of this review was to provide an overview of the role of EGF in the healing process of corneal epithelial cells after trauma.
authors.affiliation: Eye Institution of Xiamen University, Xiamen, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Zu-Guo
authors.initials: ZG
authors.lastname: Liu
mesh_terms: D004815:Epidermal Growth Factor; D066246:ErbB Receptors; D005131:Eye Injuries; D006801:Humans; D014945:Wound Healing / Q000502:physiology
chemical_list: D004815:Epidermal Growth Factor; D066246:ErbB Receptors