title: Chondrosarcoma of the arytenoid cartilage: a case report and review of the literature.
abstract: We report the case of a 56-year-old black woman with a locally aggressive chondrosarcoma at an unusual tumor site: the right arytenoid cartilage. The tumor extended from the superior pole of the right arytenoid cartilage to the soft-tissue areas of the right aryepiglottic fold, piriform sinus, and interarytenoid area. We undertook a conservative surgical approach by performing an endoscopic transoral CO2 laser resection, a right arytenoidectomy with wide soft-tissue margins, and a tracheotomy in anticipation of postoperative edema. Surgical exploration revealed that the tumor extended into the cricoid cartilage. Histopathology demonstrated a low-grade chondrosarcoma of the conventional variant. Clear margins were obtained by staged procedures. Chondrosarcomas of the larynx typically exhibit low-grade histopathology, and affected patients have a low incidence of metastasis and a good prognosis. Even so, these tumors can present diagnostic and therapeutic challenges. Surgical resection provides adequate airway protection and sound oncologic safety while preserving speech and swallowing, and these should be the surgeon's goals in this setting. Options include open laryngofissure, thyrotomy, organ preservation with partial laryngectomy, and endoscopic laser resection.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Stella
authors.initials: S
authors.lastname: Lee
authors.forename: Anthony
authors.initials: A
authors.lastname: Sparano
authors.forename: Paul
authors.initials: P
authors.lastname: Zhang
authors.forename: Natasha
authors.initials: N
authors.lastname: Mirza
mesh_terms: D001193:Arytenoid Cartilage; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008875:Middle Aged