title: Cutaneous manifestations of chikungunya fever: observations made during a recent outbreak in south India.
abstract: BACKGROUND; Chikungunya fever is an Aedes mosquito-borne Arbo viral illness with significant morbidity.
  
  
  METHODS
  In a recent outbreak of the disease in south India, the dermatologic manifestations of 145 patients attending a tertiary care hospital were recorded.
  
  
  RESULTS
  All age groups were affected, including newborns. Some of the cutaneous features were observed during the acute stage of the illness, and others during convalescence or thereafter. Pigmentary changes were found to be the most common cutaneous finding (42%), followed by maculopapular eruption (33%) and intertriginous aphthous-like ulcers (21.37%). Lesions with significant morbidity were generalized vesiculobullous eruptions (2.75%), found only in infants, lymphedema, and intertriginous aphthous-like ulcers. Exacerbation of existing dermatoses, such as psoriasis, and unmasking of undiagnosed Hansen's disease were observed. A perivascular lymphocytic infiltrate was a consistent histopathologic finding in all types of skin lesions. All patients responded well to symptomatic, conservative treatment.
  
  
  CONCLUSIONS
  The cutaneous findings hitherto not reported may be the result of the African genotype of the virus detected during this outbreak in India.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, BLDEA's SBMP Medical College, Hospital and Research Center, Bijapur, Karnataka, India. aruninamadar@rediffmail.com
authors.forename: Arun C
authors.initials: AC
authors.lastname: Inamadar
authors.forename: Aparna
authors.initials: A
authors.lastname: Palit
authors.forename: V V
authors.initials: VV
authors.lastname: Sampagavi
authors.forename: S
authors.initials: S
authors.lastname: Raghunath
authors.forename: N S
authors.initials: NS
authors.lastname: Deshmukh
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018354:Alphavirus Infections / Q000453:epidemiology*; D018771:Arthralgia / Q000821:virology; D002646:Chikungunya virus; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D005334:Fever / Q000821:virology; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000453:epidemiology / Q000821:virology*