title: Using a deformable surface model to obtain a shape representation of the cortex.
abstract: This paper examines the problem of obtaining a mathematical representation of the outer cortex of the human brain, which is a key problem in several applications, including morphological analysis of the brain, and spatial normalization and registration of brain images. A parameterization of the outer cortex is first obtained using a deformable surface algorithm which, motivated by the structure of the cortex, is constructed to find the central layer of thick surfaces. Based on this parameterization, a hierarchical representation of the outer cortical structure is proposed through its depth map and its curvature maps at various scales. Various experiments on magnetic resonance data are presented.
authors.affiliation: Dept. of Radiol. & Radiol. Sci., Johns Hopkins Univ., Baltimore, MD.
authors.forename: C
authors.initials: C
authors.lastname: Davatzikos
authors.forename: N
authors.initials: N
authors.lastname: Bryan