title: [A case of long-term survival of 5 years after operation and chemotherapy for type 4 gastric cancer with peritoneal dissemination].
abstract: We report a case of long-term survival of 5 years after operation and chemotherapy for type 4 gastric cancer with peritoneal dissemination. A 41-year-old woman underwent total gastrectomy for type 4 gastric cancer with peritoneal dissemination and pancreas invasion. After operation, chemotherapy with S-1 plus PSK therapy, S-1 plus CDDP, and S-1 plus DOC was performed. The regimen of S-1 plus CDDP included S-1 on day 1-5, 8-12, 15-19, 22-26 and 2 weeks rest and PSK daily. After S-1 plus PSK therapy(34th course), peritoneal recurrence caused ileus, so a right hemicolonectomy was performed. Now the patient is undergoing weekly paclitaxel. The S-1 plus PSK therapy is able to prolong time to progression and has fewer adverse effects.
authors.affiliation: Dept. of Surgery, Yokohama City University, School of Medicine.
authors.forename: Takanobu
authors.initials: T
authors.lastname: Yamada
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Rino
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Wada
authors.forename: Norio
authors.initials: N
authors.lastname: Yukawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Saeki
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Arai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kanari
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakayama
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
authors.forename: Hisashi
authors.initials: H
authors.lastname: Oshiro
authors.forename: Toshio
authors.initials: T
authors.lastname: Imada
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D013997:Time Factors