Early and late endophthalmitis following trabeculectomy in a Chinese population.
OBJECTIVE
To investigate the rate of bleb-related endophthalmitis over 5 years in a Chinese population. METHODS.:Retrospective chart review.


RESULTS
Of 988 trabeculectomies performed over 5 years, one case (0.1%) developed early endophthalmitis caused by Morganella morganii, which was rarely reported in the literature. Six cases (0.6%) developed late-onset endophthalmitis. Mitomycin C significantly increased the risk of late-onset endophthalmitis (p=0.0002).


CONCLUSIONS
Physicians should weigh the benefits against the risks of mitomycin C application in performing trabeculectomies.
Kuang
T-M
TM
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Lin
Y-C
YC
Liu
C Jui-Ling
CJ
Hsu
W-M
WM
Chou
C-K
CK
D000328:Adult; D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D044466:Asian People / Q000208:ethnology; D002681:China / Q000453:epidemiology; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology*; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D020613:Morganella morganii / Q000302:isolation & purification; D011183:Postoperative Complications; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013290:Streptococcal Infections / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology; D014130:Trabeculectomy; D034363:Viridans Streptococci / Q000302:isolation & purification; D014822:Vitreous Body / Q000382:microbiology
D000477:Alkylating Agents; D000900:Anti-Bacterial Agents; D016685:Mitomycin