title: The evaluation incidence and risk factors of mortality among patients with end stage renal disease in southeast Turkey.
abstract: OBJECTIVE
  End stage renal disease (ESRD) presents with higher morbidity and mortality with respect to the general population. In recent study, the causes of mortality and associated risk factors in ESRD have been evaluated.
  
  
  METHODS
  In this study, 1538 patients diagnosed with ESRD in 10-year period were evaluated retrospectively. The patients were divided as dead (group 1) and alive (group 2). The patients' demographic features, causes of death, comorbidity at hospitalization, hematological and biochemical analyses, creatinine clearance at the beginning of hospitalization, daily urine volume, blood gas results, CRP value as inflammatory marker, ejection fraction, interventricular septum diameter, left ventricle posterior wall end-diastolic diameter, and left atrium diameter determined with echocardiography were recorded.
  
  
  RESULTS
  Mortality ratio of ESRD patients in a 10-year period was 14.1%. While the general mean age of all patients was 54.7 +/- 16.6 and male/female ratio was 781/757, these ratios were 66.3 +/- 21.8 and 114/103 in Group 1 and 52.8 +/- 21.7 and 667/654 in Group 2. One or more comorbid pathologies were present in 82.9% of Group 1. The most common cause of mortality was cardiovascular diseases (CVD), and the most common cause of comorbidity was infections. Older age, anemia, absence of residual renal function, hypoalbuminemia, inflammation, impaired Ca and P metabolism, and left ventricular hypertrophy were significantly higher in Group 1 than in Group 2.
  
  
  CONCLUSIONS
  CVD are the most important preventable causes of morbidity and mortality in all stages of chronic kidney disease. Taking precaution against CVD and the associated complications will provide a positive contribution in reducing morbidity and mortality among ESRD patients.
authors.affiliation: Department of Nephrology, Medicine Faculty in Dicle University, Diyarbakir, Turkey. drdede75@gmail.com
authors.forename: Dede
authors.initials: D
authors.lastname: Sit
authors.forename: Ali Kemal
authors.initials: AK
authors.lastname: Kadiroglu
authors.forename: Hasan
authors.initials: H
authors.lastname: Kayabasi
authors.forename: Ismail Hamdi
authors.initials: IH
authors.lastname: Kara
authors.forename: Zulfukar
authors.initials: Z
authors.lastname: Yilmaz
authors.forename: M Emin
authors.initials: ME
authors.lastname: Yilmaz
mesh_terms: D002423:Cause of Death; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000150:complications / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology