Enhanced Fe ion-uptake activity in Helicobacter pylori strains isolated from patients with iron-deficiency anemia.
Recent studies have suggested a link between iron-deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron-deficiency anemia showed enhanced Fe ion uptake and Fe ion-dependent rapid growth compared with those from patients with non-iron-deficiency anemia. H. pylori with enhanced Fe ion-uptake ability may be a causative factor for iron-deficiency anemia.
Yokota
Shin-ichi
S
Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Konno
Mutsuko
M
Mino
Emi
E
Sato
Kohei
K
Takahashi
Michiko
M
Fujii
Nobuhiro
N
D000293:Adolescent; D018798:Anemia, Iron-Deficiency / Q000150:complications* / Q000209:etiology; D002648:Child; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification* / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008297:Male
D007501:Iron