title: Spontaneous intracranial hypotension syndrome in a patient with marfan syndrome and autosomal dominant polycystic kidney disease.
abstract: Intracranial hypotension is typically manifested by orthostatic headache. The most frequent underlying factor is cerebrospinal fluid leakage. It has been suggested that dural structural weakness in some connective tissue diseases may be responsible for dural tears and diverticula and consequently leakage. We present a case of spontaneous intracranial hypotension associated with Marfan syndrome and autosomal dominant polycystic kidney disease. The patient was treated successfully with epidural autologous blood patch. Dural involvements of these hereditary connective tissue diseases are also discussed.
authors.affiliation: Division of Neuroradiology, Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, and General Practice/Family Medicine, Haseki Education and Research Hospital, Istanbul, Turkey.
authors.forename: Sait
authors.initials: S
authors.lastname: Albayram
authors.forename: Ahmet
authors.initials: A
authors.lastname: Baş
authors.forename: Harun
authors.initials: H
authors.lastname: Ozer
authors.forename: Suleyman
authors.initials: S
authors.lastname: Dikici
authors.forename: Serap Yavuz
authors.initials: SY
authors.lastname: Gulertan
authors.forename: Adnan
authors.initials: A
authors.lastname: Yuksel
mesh_terms: D000328:Adult; D017217:Blood Patch, Epidural; D015170:Cerebrospinal Fluid Pressure; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000628:therapy; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008382:Marfan Syndrome / Q000150:complications* / Q000503:physiopathology; D007690:Polycystic Kidney Diseases / Q000150:complications*