title: [Cognitive performance in patients with coronary heart disease and cardiovascular risk factors in Chile].
abstract: BACKGROUND
  Cardiovascular risk factors (CRF) are related to long-term cognitive impairment. Coronary heart disease (CHD) has been associated with bad cognitive performance in an inconsistent way. AIM. To measure the cognitive performance in Chilean patients with diverse CRF, with and without CHD.
  
  
  METHODS
  Cross-sectional study of the cognitive performance of three groups of patients older than sixty years, without history of stroke: with CHD and high CRF (CHD-hCRF) (n = 62), with high CRF but without CHD (hCRF) (n = 57), and non hypertensive non diabetic (NHND) (n = 25).
  
  
  RESULTS
  Higher age, lower education and been men were significantly associated with cognitive impairment in the total sample. There were no differences in the proportion of cognitive impairment and age between the groups. The CHD group had a predominance of men and a higher proportion of high cholesterol and periphery vascular disease than the other groups. The NHND group was more educated than the other groups. After adjusting for years of education and sex there were no significant differences in the neuropsychological performance and depression scales between the groups, been the coronary group significantly more functionally impaired.
  
  
  CONCLUSIONS
  Isolated CHD is not associated with worse cognitive performance in patients, but it is related with greater systemic vascular damage and functional impairment in patients without history of stroke.
authors.affiliation: Hospital Clinico Universidad de Chile, Santiago de Chile, Chile. carodede@gmail.com
authors.forename: C
authors.initials: C
authors.lastname: Delgado-Derio
authors.forename: C
authors.initials: C
authors.lastname: Vasquez-Vivar
authors.forename: P
authors.initials: P
authors.lastname: Orellana-Pineda
authors.forename: A
authors.initials: A
authors.lastname: Reccius-Meza
authors.forename: A
authors.initials: A
authors.lastname: Donoso-Sepúlveda
authors.forename: M I
authors.initials: MI
authors.lastname: Behrens-Pellegrino
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000150:complications; D002677:Chile; D003072:Cognition Disorders / Q000209:etiology*; D003327:Coronary Disease / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors