title: Synthesis of (-)-Indolizidine 167B based on domino hydroformylation/cyclization reactions.
abstract: The synthesis of (-)-Indolizidine 167B has been achieved from optically active (R)-3-(pyrrol-1-yl)hex-1-ene. The key step is a highly regioselective hydroformylation reaction and a one-pot intramolecular cyclization providing a general approach to the indolizine nucleus.
authors.affiliation: ICCOM-CNR, Sezione di Pisa, Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Via Risorgimento 35, 56126 Pisa, Italy. Giuditta.Guazzelli@manchester.ac.uk
authors.forename: Giuditta
authors.initials: G
authors.lastname: Guazzelli
authors.forename: Raffaello
authors.initials: R
authors.lastname: Lazzaroni
authors.forename: Roberta
authors.initials: R
authors.lastname: Settambolo