title: Subdural hematoma associated with dural metastasis of gastric carcinoma: report of two cases.
abstract: We treated two cases of a subdural hematoma associated with dural metastasis of gastric cancer, from which both patients died. Case 1: A 60-year-old female patient was hospitalized with a diagnosis of type 4 gastric cancer of the antrum. The patient suddenly collapsed, and, subsequently, left hemiplegia and a depressed level of consciousness were noted. A head computed tomography (CT) scan revealed a subdural hematoma with midline shift. The patient was diagnosed with chronic subdural hematoma and underwent emergency burr hole irrigation. Case 2: A 73-year-old man was diagnosed with type 4 gastric cancer and a total gastrectomy plus splenectomy were performed together with dissection of the N1 and N2 lymph node groups (D2 dissection) in March 2006 (T3, N2, P0, H0, INFgamma, ly3, v0, por2). Postoperative adjuvant chemotherapy was performed using oral TS-1; following tests revealed no recurrence in the abdomen. In December 2006, gingival bleeding was noted with disseminated intravascular coagulation (DIC) and 10 days later, the patient was hospitalized with chief complaints of impaired consciousness and anorexia. CT scan revealed a right subdural hematoma with a midline shift. The patient was diagnosed with chronic subdural hematoma and underwent emergency burr hole irrigation and drainage. The dural biopsy of the two cases revealed adenocarcinoma noted in the dural blood vessel. Special staining revealed CEA-positive adenocarcinoma, and a diagnosis of the dural metastasis of gastric cancer was made. These patients' level of consciousness significantly improved postoperatively. However, DIC developed concurrently, and the patients died on the 13th and 14th postoperative day, respectively.
authors.affiliation: Department of Surgery, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Katsube
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kikuchi
authors.forename: Soichi
authors.initials: S
authors.lastname: Konnno
authors.forename: Minoru
authors.initials: M
authors.lastname: Murayama
authors.forename: Rie
authors.initials: R
authors.lastname: Kobayashi
authors.forename: Kotaro
authors.initials: K
authors.lastname: Kuhara
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshimatsu
authors.forename: Shunnichi
authors.initials: S
authors.lastname: Shiozawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimakawa
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Naritaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Ogawa
authors.forename: Shinnji
authors.initials: S
authors.lastname: Hagiwara
authors.forename: Motohiko
authors.initials: M
authors.lastname: Aiba
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D004388:Dura Mater / Q000473:pathology*; D005260:Female; D046648:Hematoma, Subdural, Intracranial / Q000209:etiology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000556:secondary*; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed