An electrochemical approach for the detection of HIV-1 protease.
An electrochemical biosensor with a new bioorganometallic approach for the detection of human immunodeficiency virus (HIV) type 1 protease (HIV-1 PR) using surface-bound ferrocenoyl (Fc)-pepstatin conjugates is presented.
Kerman
Kagan
K
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan, S7N 5C9, Canada.
Mahmoud
Khaled A
KA
Kraatz
Heinz-Bernhard
HB
D015374:Biosensing Techniques / Q000379:methods; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D016333:HIV Protease / Q000032:analysis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D000075163:Metallocenes; D008968:Molecular Conformation; D010436:Pepstatins / Q000737:chemistry*; D013499:Surface Properties
D005296:Ferrous Compounds; D000075163:Metallocenes; D010436:Pepstatins; D006046:Gold; D016333:HIV Protease; C514803:p16 protease, Human immunodeficiency virus 1; C004998:ferrocene; C031375:pepstatin