Current status and future potential of MRI-guided focused ultrasound surgery.
The combination of the imaging abilities of magnetic resonance imaging (MRI) with the ability to delivery energy to targets deep in the body noninvasively with focused ultrasound presents a disruptive technology with the potential to significantly affect healthcare. MRI offers precise targeting, visualization, and quantification of temperature changes and the ability to immediately evaluate the treatment. By exploiting different mechanisms, focused ultrasound offers a range of therapies, ranging from thermal ablation to targeted drug delivery. This article reviews recent preclinical and tests clinical of this technology.
Jolesz
Ferenc A
FA
Department of Radiology, Harvard Medical School, Boston, MA 02115, USA.
McDannold
Nathan
N
D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000639:trends*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods / Q000639:trends; D014464:Ultrasonic Therapy / Q000379:methods* / Q000639:trends*