title: Comparison of optic disc margin identified by color disc photography and high-speed ultrahigh-resolution optical coherence tomography.
abstract: OBJECTIVE
  To determine the correspondence between optic disc margins evaluated using disc photography (DP) and optical coherence tomography (OCT).
  
  
  METHODS
  From May 1, 2005, through November 10, 2005, 17 healthy volunteers (17 eyes) had raster scans (180 frames, 501 samplings per frame) centered on the optic disc taken with stereo-optic DP and high-speed ultrahigh-resolution OCT (hsUHR-OCT). Two image outputs were derived from the hsUHR-OCT data set: an en face hsUHR-OCT fundus image and a set of 180 frames of cross-sectional images. Three ophthalmologists independently and in a masked, randomized fashion marked the disc margin on the DP, hsUHR-OCT fundus, and cross-sectional images using custom software. Disc size (area and horizontal and vertical diameters) and location of the geometric disc center were compared among the 3 types of images.
  
  
  RESULTS
  The hsUHR-OCT fundus image definition showed a significantly smaller disc size than the DP definition (P <.001, mixed-effects analysis). The hsUHR-OCT cross-sectional image definition showed a significantly larger disc size than the DP definition (P <.001). The geometric disc center location was similar among the 3 types of images except for the y-coordinate, which was significantly smaller in the hsUHR-OCT fundus images than in the DP images.
  
  
  CONCLUSIONS
  The optic disc margin as defined by hsUHR-OCT was significantly different than the margin defined by DP.
authors.affiliation: UPMC Eye Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
authors.forename: Anita
authors.initials: A
authors.lastname: Manassakorn
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Jong S
authors.initials: JS
authors.lastname: Kim
authors.forename: Gadi
authors.initials: G
authors.lastname: Wollstein
authors.forename: Richard A
authors.initials: RA
authors.lastname: Bilonick
authors.forename: Larry
authors.initials: L
authors.lastname: Kagemann
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Gabriele
authors.forename: Kyung Rim
authors.initials: KR
authors.lastname: Sung
authors.forename: Tarkan
authors.initials: T
authors.lastname: Mumcuoglu
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
authors.forename: Joel S
authors.initials: JS
authors.lastname: Schuman
mesh_terms: D000328:Adult; D019412:Anatomy, Cross-Sectional; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000033:anatomy & histology*; D010781:Photography / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*