Content of beta-casomorphins in milk of women with a history of allergy.
The prevalence of food allergies increased over the past decade. Most symptoms of food allergy appear during the first 2 yr of life. The aim of this study was to determine the beta-casomorphin-5 and -7 (BCMs) in colostrum and milk of 12 breast-feeding women with a history and clinical manifestation of food allergy. The results were compared with the data obtained from a control group of healthy age-matched breast-feeding women. The level of BCM in women with food allergy was constant during lactation, whereas the highest level of opioid peptides was found in colostrums of healthy women with a subsequent rapid decrease in mature milk. These differences in BCMs profile between allergic and healthy breast-feeding women suggest that BCM content in the human milk may be an indicator of allergic conditions.
Sidor
Katarzyna
K
Third Department of Paediatric Diseases, Medical University, Bialystok, Poland.
Jarmołowska
Beata
B
Kaczmarski
Maciej
M
Kostyra
Elzbieta
E
Iwan
Matgorzata
M
Kostyra
Henryk
H
D000328:Adult; D001942:Breast Feeding; D003126:Colostrum / Q000737:chemistry / Q000276:immunology*; D004723:Endorphins / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D006801:Humans; D016269:Milk Hypersensitivity / Q000276:immunology*; D008895:Milk, Human / Q000737:chemistry* / Q000276:immunology; D011247:Pregnancy
D004723:Endorphins; C021968:beta-casomorphins