title: [Bronchiolo-alveolar cell carcinoma of the lung presenting as spontaneous pneumothorax].
abstract: A 30-year old man visited a local clinic complaining of dyspnea and chest pain. He had a history of hepatocystadenocarcinoma 10 years before. Pneumothorax was diagnosed. Immediately, the patient was referred to us and underwent a tube thoracostomy. Cytologic examination of pleural effusion specimens revealed malignant cells. Because pleural drainage and pleurodesis using anti-cancer agents were not effective, we performed a thoracotomy. A tumor with accompanying bulla was detected in the right S6 region and a right lower lobectomy was performed. Histologic examination of tumor specimens disclosed bronchiolo-alveolar cell carcinoma. We speculated that bullae formed by tumor invasion, had burst, resulting in pneumothorax. This was a case of asynchronous double cancer in a relatively young patient, and the first report in Japan of bronchiolo-alveolar cell carcinoma presenting with spontaneous pneumothorax as an initial symptom.
authors.affiliation: Division of Internal Medicine, Kure Kyosai Hospital, 2-3-28 Nishichuou Kure, Hiroshima, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Hiyama
authors.forename: A
authors.initials: A
authors.lastname: Hiraki
authors.forename: H
authors.initials: H
authors.lastname: Ueoka
authors.forename: K
authors.initials: K
authors.lastname: Kanazawa
authors.forename: M
authors.initials: M
authors.lastname: Marukawa
authors.forename: Y
authors.initials: Y
authors.lastname: Shiota
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000150:complications*; D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D011030:Pneumothorax / Q000209:etiology*