title: Castleman's disease of the neck.
abstract: Castleman's disease is an uncommon benign disease of unknown etiology that induces reactive lymph node hyperplasia. There are 2 histologic subtypes of Castleman's disease: hyaline vascular type and plasma cell type. Tissue biopsy is necessary for a definitive diagnosis. Castleman's disease of the neck occurs rarely. On reviewing the literature, most Castleman's disease of the neck presented with a single mass. We report here an 80-year-old man with 2 neck masses of 1 year's duration. A 4-cm firm movable mass in the left submandibular area and another 2-cm firm movable mass in the left level IV area were noted. The patient was diagnosed with Castleman's disease of the neck after resection of 1 of the masses. There was no evidence of progression or recurrence of the disease after 21 months of follow-up. We suggest that this was a rare case of multicentric cervical Castleman's disease.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Taichung, Taiwan, R O C.
authors.forename: Chih-Cheng
authors.initials: CC
authors.lastname: Chen
authors.forename: Rong-San
authors.initials: RS
authors.lastname: Jiang
authors.forename: Guan
authors.initials: G
authors.lastname: Chou
authors.forename: Ching-Ping
authors.initials: CP
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005871:Castleman Disease / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009333:Neck; D014057:Tomography, X-Ray Computed