title: [Esophageal manometry and 24-hour pH monitoring in the remnant esophagus after esophagectomy and esophagogastric anastomosis following esophageal bed].
abstract: OBJECTIVE
  To investigate the motility function of remnant esophagus and stomach, and the gastroesophageal reflux after esophagectomy and esophagogastric anastomosis following esophageal bed.
  
  
  METHODS
  Esophageal manometry and 24-hour pH monitoring were performed in 10 healthy volunteers and 20 patients who underwent esophagectomy and esophagogastric anastomosis through esophageal bed as a treatment for mid-esophageal carcinoma. These 20 patients, received examinations within 3 to 6 months after operations, were defined as study group, and 10 healthy volunteers as control group.
  
  
  RESULTS
  (1) All the pH monitoring indexes in study group were significantly higher than those in control group (P<0.01). (2) Rest pressures of stomach, remnant esophagus and upper esophageal sphincter significantly increased in comparison with control group(P<0.01). (3) The contracting pressure, amplitude of primary peristalsis and amplitude of swallow peristalsis of remnant esophagus were reduced as compared to control group(P<0.01). (4) The contraction pressure of upper esophageal sphincter was obviously higher than that of control group (P<0.01). (5) There were no significant differences among stomach rest pressure, anastomosis rest pressure and remnant esophagus rest pressure in study group (F=3.08, P>0.05).
  
  
  CONCLUSIONS
  After esophagectomy and esophagogastric anastomosis through esophageal bed in upper aortic site, the peristalsis function of remnant esophagus is poor, the function of acid clearance is reduced, no high pressure zone at the anastomosis orifice is found, the anastomosis orifice has no anti-reflux effect, and gastroesophageal reflux exists in the postoperative patients prevalently.
authors.affiliation: Department of Thoracic Cardiovascular Surgery, Zhongshan Hospital, Dalian University, Dalian 116001, China. JZL-0405@sohu.com
authors.forename: Zhi-liang
authors.initials: ZL
authors.lastname: Jiang
authors.forename: Ji-wu
authors.initials: JW
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.forename: Jian-xin
authors.initials: JX
authors.lastname: Li
mesh_terms: D000714:Anastomosis, Surgical; D016022:Case-Control Studies; D004938:Esophageal Neoplasms / Q000503:physiopathology* / Q000601:surgery; D016629:Esophagectomy; D004947:Esophagus / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005764:Gastroesophageal Reflux; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010528:Peristalsis; D011312:Pressure