title: 10-year case review of nutritional rickets in Children's Hospital of Michigan.
abstract: Nutritional rickets has been on the rise in the United States. A chart review of patients with nutritional rickets from April 1995 to May 2005 was performed. Fifty-eight subjects were studied (62% males, 38% females, with an age range between 2 and 132 months). Of the subjects, 81% were African Americans and 14% were Arabic; 33% were Christians and 19% were Muslims. An increasing number of cases of nutritional rickets have been noted since 2000. Seventy-nine percent of patients with nutritional rickets presented at the emergency department, and in 69% of the cases, rickets was an incidental finding; 96% of patients were exclusively breast-fed, and none received multivitamin supplements. 25-OH vitamin D levels were below 5 ng/mL in 42% of the patients, all of whom were African Americans. We could document complete resolution of nutritional rickets in only 8 patients, and 3 of these patients showed sequelae of rickets.
authors.affiliation: Pittsburgh Children's Hospital, Pittsburgh, Pennsylvania, USA.
authors.forename: Judith P
authors.initials: JP
authors.lastname: Lazol
authors.forename: Nedim
authors.initials: N
authors.lastname: Cakan
authors.forename: Deepak
authors.initials: D
authors.lastname: Kamat
mesh_terms: D001942:Breast Feeding / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D019587:Dietary Supplements; D005260:Female; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data*; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D007223:Infant; D008297:Male; D008824:Michigan / Q000453:epidemiology; D010361:Patients / Q000706:statistics & numerical data; D012279:Rickets / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D014807:Vitamin D / Q000008:administration & dosage / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000150:complications*; D014815:Vitamins / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D006887:Hydroxycholecalciferols; D014815:Vitamins; D014807:Vitamin D