title: [Chemoradiotherapy of unresectable and recurrent cholangiocarcinoma].
abstract: This study is for chemoradiotherapy of unresectable and recurrent cholangiocarcinoma (CCC).
  
  
  METHODS
  Between April 2005 and March 2007, 5 patients were evaluated for unresectable and recurrent CCC. All patients were performed percutaneous transhepatic biliary drainage (PTBD) and treated with chemoradiotherapy. The radiation method was an external beam radiotherapy (EBRT) and remote after loading system (RALS). The chemotherapy was 5-FU and gemcitabine by intravenous injection.
  
  
  RESULTS
  Three patients had unresectable and 2 had recurrent CCC. As for the side effects, 4 patients had a slight neutropenia and 1 had an uncontrollable gastric bleeding. No patient had cholangitis. The mean survival time for unresectable and recurrent CCC was 13.7 months and 17 months, respectively.
  
  
  CONCLUSIONS
  Our results indicated that chemoradiotherapy had been consistent with efficacy in patients with unresectable and recurrent CCC.
authors.affiliation: Dept. of Surgery, Ohmuta Municipal General Hospital.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Horiuchi
authors.forename: Mitsutoshi
authors.initials: M
authors.lastname: Ureshino
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Yoshimura
authors.forename: Satoru
authors.initials: S
authors.lastname: Matono
authors.forename: Takamasa
authors.initials: T
authors.lastname: Fukumitsu
authors.forename: Yukiya
authors.initials: Y
authors.lastname: Kishimoto
authors.forename: Hiroko
authors.initials: H
authors.lastname: Sasahara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kubota
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Takada
authors.forename: Kazunori
authors.initials: K
authors.lastname: Noguchi
authors.forename: Yuuichirou
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kawahara
authors.forename: Hiroto
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Tohru
authors.initials: T
authors.lastname: Hisaka
authors.forename: Takenori
authors.initials: T
authors.lastname: Sakai
authors.forename: Shinji
authors.initials: S
authors.lastname: Uchida
authors.forename: Hisafumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D018281:Cholangiocarcinoma / Q000097:blood / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D014408:Biomarkers, Tumor