title: Histological types of polypoid cutaneous melanoma II.
abstract: The aim of this study was to ascertain which histological types of melanoma can clinically and morphologically appear as polypoid melanomas. In 645 cases of primary cutaneous melanoma we have analyzed criteria for diagnosis of polypoid cutaneous melanoma and afterwards we have analyzed growth phase in each polypoid melanoma, histological type of atypical melanocytes, the number of epidermal ridges which are occupied by atypical melanocytes, and distribution according to age, sex and location, as well as the disease free survival. According to the criteria for polypoid melanomas we have found 147 (22.8%) polypoid cutaneous melanomas. Analyzing the growth phases, histological types of atypical melanocytes and the number of affected epidermal ridges in the group of polypoid melanomas we have ascertained 2 (1.4%) ALMs, 4 (2.8%) LMMs, 42 (28.6%) SSMs and 99 (67.2%) NMs. Our conclusion is that polypoid cutaneous melanomas are morphological forms of various histological melanoma types (ALM, LMM, SSM and NM) and they can all display polypoid morphological form. Polypoid cutaneous melanomas are most often of nodular histological type.
authors.affiliation: Department of Clinical Pathology, University Hospital for Tumors, Zagreb, Croatia.
authors.forename: Fabijan
authors.initials: F
authors.lastname: Knezević
authors.forename: Vjekoslav
authors.initials: V
authors.lastname: Duancić
authors.forename: Sanda
authors.initials: S
authors.lastname: Sitić
authors.forename: Anica
authors.initials: A
authors.lastname: Horvat-Knezević
authors.forename: Vesna
authors.initials: V
authors.lastname: Benković
authors.forename: Snjezana
authors.initials: S
authors.lastname: Ramić
authors.forename: Kresimir
authors.initials: K
authors.lastname: Kostović
authors.forename: Vesna
authors.initials: V
authors.lastname: Ramljak
authors.forename: Danko Velemir
authors.initials: DV
authors.lastname: Vrdoljak
authors.forename: Mladen
authors.initials: M
authors.lastname: Stanec
authors.forename: Angelina
authors.initials: A
authors.lastname: Bozović
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology*