title: Ictal SPECT in Sturge-Weber syndrome.
abstract: We report on a patient with right-sided Sturge-Weber syndrome (SWS), in whom earlier functional hemispherectomy failed. Subtraction of ictal and interictal single-photon-emission-computed-tomography (SPECT) superimposed on individual MRI showed a right fronto-orbital hyperperfusion, with a left-sided EEG seizure pattern. Ictal SPECT supported our assumption that right frontal originated seizure pattern propagated to left hemisphere via the remaining right frontal bridge. Right orbito-frontal resection and disconnection from corpus callosum resulted in seizure freedom.
authors.affiliation: University of Munich, Klinikum Grosshadern; Department of Neurology, Germany. ozgurbilgin1@yahoo.com
authors.forename: Ozgür
authors.initials: O
authors.lastname: Bilgin
authors.forename: Christian
authors.initials: C
authors.lastname: Vollmar
authors.forename: Aurelia
authors.initials: A
authors.lastname: Peraud
authors.forename: Christian
authors.initials: C
authors.lastname: la Fougere
authors.forename: Pedro
authors.initials: P
authors.lastname: Beleza
authors.forename: Soheyl
authors.initials: S
authors.lastname: Noachtar
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D003337:Corpus Callosum / Q000601:surgery; D004351:Drug Resistance; D004569:Electroencephalography; D005625:Frontal Lobe / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures; D010291:Paresis / Q000209:etiology; D012640:Seizures / Q000000981:diagnostic imaging* / Q000209:etiology; D013341:Sturge-Weber Syndrome / Q000150:complications / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000927:Anticonvulsants