title: [Diffusion- and perfusion-weighted magnetic resonance imaging: possibilities and perspectives].
abstract: The article addresses theoretical and practical issues of using diffusion- (DW-MRI) and perfusion-weighted (PW-MRI) magnetic resonance tomography in acute period of ischemic stroke. The authors consider prognostic value of the results obtained with both methods of MRI-diagnosis and possibilities of their usage in pathophysiological studies of ischemic stroke. Prognostic value of DW-MRI in measuring of final size of stroke used at the first day of stroke is higher compared to standard regimes. A ratio between clinical and MRI data has been analyzed. A conception comparing a ratio between the presence of lesion and its size using DW-MRI and PW-MRI is presented. A longer duration of the penumbra comparing to conventional terms was described. The results of DW-MRI and PW-MRI study are suggested to be used for prognostic purpose as well as for elaboration of an optimal treatment tactics. Some controversial issues of using DW-MRI and PW-MRI, are discussed.
authors.forename: Z A
authors.initials: ZA
authors.lastname: Suslina
authors.forename: R M
authors.initials: RM
authors.lastname: Umarova
authors.forename: M V
authors.initials: MV
authors.lastname: Krotenkova
authors.forename: R N
authors.initials: RN
authors.lastname: Konovalov
authors.forename: M M
authors.initials: MM
authors.lastname: Tanashian
authors.forename: M A
authors.initials: MA
authors.lastname: Piradov
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015203:Reproducibility of Results; D012720:Severity of Illness Index