title: Dengue and dengue hemorrhagic fever in the State of Pernambuco, 1995-2006.
abstract: In Pernambuco, the first dengue cases occurred in 1987. After a seven-year interval without autochthonous cases, a new epidemic occurred in 1995. Important aspects of the dengue epidemics during the period 1995-2006 have been analyzed here, using epidemiological, clinical and laboratory data. A total of 378,374 cases were notified, with 612 confirmed cases of dengue hemorrhagic fever and 33 deaths. The mortality rate was 5.4%. The incidence rate increased from 134 to 1,438/100,000 inhabitants, corresponding to the epidemics due to serotypes 2 and 3, in 1995 and 2002, respectively. Dengue mainly affected adults (20-49 years); 40.7% were male and 59.3% were female. From 2003 onwards, the number of cases among individuals younger than 15 years old increased. Out of 225 dengue hemorrhagic fever cases, 42.7% primary and 57.3% secondary infections were identified (p = 0.0279). Neurological manifestations were also observed. From 2002 onwards, serotypes 1, 2 and 3 were circulating; serotype 3 was predominant.
authors.affiliation: Laboratório Central de Saúde de Pública, Secretaria de Saúde do Estado de Pernambuco, Recife, PE, Brasil. marli@cpqam.fiocruz.br
authors.forename: Marli Tenório
authors.initials: MT
authors.lastname: Cordeiro
authors.forename: Hermann Gonçalves
authors.initials: HG
authors.lastname: Schatzmayr
authors.forename: Rita Maria Ribeiro
authors.initials: RM
authors.lastname: Nogueira
authors.forename: Valdete Felix de
authors.initials: VF
authors.lastname: Oliveira
authors.forename: Wellinton Tavares de
authors.initials: WT
authors.lastname: Melo
authors.forename: Eduardo Freese de
authors.initials: EF
authors.lastname: Carvalho
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D019595:Severe Dengue / Q000453:epidemiology