Surface-induced dissociation of small molecules, peptides, and non-covalent protein complexes.
This article provides a perspective on collisions of ions with surfaces, including surface-induced dissociation (SID) and reactive ion scattering spectrometry (RISS). The content is organized into sections on surface-induced dissociation of small ions, surface characterization of organic thin films by collision of well-characterized ions into surfaces, the use of SID to probe peptide fragmentation, and the dissociation of large non-covalent complexes by SID. Examples are given from the literature with a focus on experiments from the authors' laboratory. The article is not a comprehensive review but is designed to provide the reader with an overview of the types of results possible by collisions of ions into surfaces.
Wysocki
Vicki H
VH
Department of Chemistry, University of Arizona, Tucson, Arizona 85721-0041, USA. vwysocki@email.arizona.edu
Joyce
Karen E
KE
Jones
Christopher M
CM
Beardsley
Richard L
RL
D001363:Awards and Prizes; D013058:Mass Spectrometry; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis* / Q000737:chemistry*; D011506:Proteins / Q000032:analysis* / Q000737:chemistry*; D013499:Surface Properties
D010455:Peptides; D011506:Proteins