Assessment of myocardial viability: comparison of echocardiography versus cardiac magnetic resonance imaging in the current era.
Detecting viable myocardium, whether hibernating or stunned, is of clinical significance in patients with coronary artery disease and left ventricular dysfunction. Echocardiographic assessments of myocardial thickening and endocardial excursion during dobutamine infusion provide a highly specific marker for myocardial viability, but with relatively less sensitivity. The additional modalities of myocardial contrast echocardiography and tissue Doppler have recently been proposed to provide further, quantitative measures of myocardial viability assessment. Cardiac magnetic resonance (CMR) has become popular for the assessment of myocardial viability as it can assess cardiac function, volumes, myocardial scar, and perfusion with high-spatial resolution. Both 'delayed enhancement' CMR and dobutamine stress CMR have important roles in the assessment of patients with ischaemic cardiomyopathy. This article reviews the recent advances in both echocardiography and CMR for the clinical assessment of myocardial viability. It attempts to provide a pragmatic approach toward the patient-specific assessment of this important clinical problem.
Tomlinson
David R
DR
Department of Cardiology, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Becher
Harald
H
Selvanayagam
Joseph B
JB
D004452:Echocardiography / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000473:pathology*; D012680:Sensitivity and Specificity