Transmission of tropical and geographically restricted infections during solid-organ transplantation.
In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included.
Martín-Dávila
P
P
Servicio de Enfermedades Infecciosas, Hospital Ramón y Cajal, Ctra. Colmenar km. 9,100, 28034 Madrid, Spain. pmartin.hrc@salud.madrid.org
Fortún
J
J
López-Vélez
R
R
Norman
F
F
Montes de Oca
M
M
Zamarrón
P
P
González
M I
MI
Moreno
A
A
Pumarola
T
T
Garrido
G
G
Candela
A
A
Moreno
S
S
D000818:Animals; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D017408:Guidelines as Topic; D006801:Humans; D009181:Mycoses / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission; D016377:Organ Transplantation / Q000009:adverse effects / Q000592:standards*; D010272:Parasitic Diseases / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission; D014019:Tissue Donors; D014195:Travel; D014329:Tropical Climate; D014777:Virus Diseases / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission