[Antimicrobial effect of 4-(adamantyl-1)-1-(1-aminobutyl)benzol].
Antimicrobial activity in vitro of adamantine derivative in respect of aerobic and anaerobic microorganisms has been studied. In these conditions Gram-positive bacteria and some representatives of Gram-negative microorganisms (Shigella flexneri, S. newvcastle, Enterobacter aerogenes etc.) had maximal sensitivity (MIC 0.6-5.0 and 0.1-5.0 mg/ml, respectively). Pseudomonas aeruginosa were resistant to this substance (MIC >1 mg/ml).
Vrynchanu
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D000218:Adamantane / Q000031:analogs & derivatives* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006088:Gram-Negative Aerobic Bacteria / Q000187:drug effects; D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects; D006095:Gram-Positive Cocci / Q000187:drug effects; D016987:Gram-Positive Rods / Q000187:drug effects; D008826:Microbial Sensitivity Tests
C526861:4-(adamantyl-1)-1-(1-aminobutyl)benzol; D000900:Anti-Bacterial Agents; D000218:Adamantane