title: Deep venous thrombosis in adolescents due to anatomic causes.
abstract: Aberrant or anomalous anatomy is an under appreciated risk for venous thromboembolic events (VTE). Five adolescents with VTE and predisposing anatomic abnormalities are presented. In three cases, knowledge of the underlying anatomic abnormalities resulted in changes in treatment and management. In two other cases, failure to consider or correct the underlying defect resulted in recurrent thrombosis or post-thrombotic complications. Few case reports are found in the pediatric literature, but a MEDLINE search across all age groups suggests these anomalies are frequently found when appropriate radiological imaging is obtained.
authors.affiliation: Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Bruins
authors.forename: Margaret
authors.initials: M
authors.lastname: Masterson
authors.forename: Richard A
authors.initials: RA
authors.lastname: Drachtman
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Michaels
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010690:Phlebography; D018608:Ultrasonography, Doppler; D014680:Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*