Infantile pyoderma gangrenosum.
Pyoderma gangrenosum (PG) is rare in infants. There have been 12 cases of PG in infants (<12 months old) reported in the past 25 years, to our knowledge. Six of these cases have been successfully controlled with systemic steroids, and one case with topical steroids alone. We report a case of an 8-month-old infant whose PG was aggressive and unresponsive to systemic steroids. Adjuvant treatment with cyclosporine was required to achieve healing. We review the previous cases of infantile PG and the therapeutic options in this age group.
McAleer
Maeve A
MA
Regional Centre of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland. maeve_mc_aleer@hotmail.com
Powell
Frank C
FC
Devaney
Deirdre
D
O'Donnell
Brigid F
BF
D001623:Betamethasone / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D005672:Fusidic Acid / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000188:drug therapy*; D012837:Silver Sulfadiazine / Q000627:therapeutic use
D005672:Fusidic Acid; D016572:Cyclosporine; D001623:Betamethasone; D011239:Prednisolone; D012837:Silver Sulfadiazine