Dengue fever with ischemic stroke: a case report.
BACKGROUND
Dengue fever, especially dengue hemorrhagic fever, often presents with thrombocytopenia and hemorrhagic phenomenon. Neurologic manifestations are uncommon.


RESULTS
We report a case of dengue fever with thrombocytopenia and ischemic stroke. Only supportive treatment was instituted. The neurologic deficits of the patient were initially progressive and then improved. The platelet count correlated well with the disease severity and the neurologic deficits. The time course was compatible with the critical stage in dengue hemorrhagic fever. Some studies show that immunomodulators or immunosuppressants may reverse thrombocytopenia such that the bleeding episodes improve rapidly.


CONCLUSIONS
Dengue fever may present as ischemic stroke.
Liou
Li-Min
LM
Department of Neurology, Kaohsiung Municipal Hsiaokang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Lan
Sheng-Hsing
SH
Lai
Chiou-Lian
CL
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001831:Body Temperature / Q000502:physiology; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D003715:Dengue / Q000150:complications* / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology / Q000503:physiopathology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010976:Platelet Count; D020521:Stroke / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D013786:Thalamic Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D013788:Thalamus / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D013921:Thrombocytopenia / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D010975:Platelet Aggregation Inhibitors