Clinicopathologic correlation in IgA nephropathy.
IgA nephropathy is the most common biopsy-proven pattern of glomerulonephritis in the world. Many factors, both clinical and histologic, have been suggested to impact on prognosis. We review the wide variations in how patients with immunoglobulin A nephropathy can present and the important differences derived from the clinical pathologic setting through the description of 4 cases. These include the clinical scenarios of modest proteinuria, acute kidney injury, and the nephrotic syndrome.
Philibert
David
D
University Health Network, Toronto General Research Institute, Toronto, Canada.
Cattran
Daniel
D
Cook
Terence
T
D000328:Adult; D001707:Biopsy, Needle; D018450:Disease Progression; D005260:Female; D005920:Glomerular Mesangium / Q000473:pathology*; D005922:Glomerulonephritis, IGA / Q000473:pathology* / Q000503:physiopathology*; D006417:Hematuria; D006801:Humans; D008297:Male; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000473:pathology; D009404:Nephrotic Syndrome / Q000473:pathology; D011507:Proteinuria