title: [Molecular basis of microbial adherence to prosthetic materials. Role of biofilms in prosthesis-associated infection].
abstract: Adherence of microorganisms to a surface is the first step in the formation of most biofilms. Adherence can take place on both virgin material and material coated with proteins or glycoproteins generated by the host. The importance of these mechanisms depends on the type of implant. In this review we will discuss the molecular basis of bacterial adherence to inert material, the implication of adherence in biofilm formation, and the advantages of biofilm production by bacteria causing prosthesis-associated infection.
authors.affiliation: Servicio de Microbiología, Centro de Diagnóstico Biomédico, Hospital Clínico, Barcelona, España. jvila@ub.edu
authors.forename: Jordi
authors.initials: J
authors.lastname: Vila
authors.forename: Alex
authors.initials: A
authors.lastname: Soriano
authors.forename: José
authors.initials: J
authors.lastname: Mensa
mesh_terms: D018829:Adhesins, Bacterial / Q000502:physiology; D001422:Bacterial Adhesion; D001672:Biocompatible Materials / Q000737:chemistry; D018441:Biofilms; D004866:Equipment Contamination; D004926:Escherichia coli / Q000502:physiology; D016326:Extracellular Matrix Proteins / Q000502:physiology; D010861:Fimbriae, Bacterial / Q000502:physiology; D006801:Humans; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000382:microbiology* / Q000503:physiopathology; D011549:Pseudomonas / Q000502:physiology; D013210:Staphylococcus / Q000502:physiology
chemical_list: D018829:Adhesins, Bacterial; D001672:Biocompatible Materials; D016326:Extracellular Matrix Proteins