title: Free tissue transfer and deep vein thrombosis.
abstract: Reconstruction of the post-oncologic defect of the lower limb frequently requires free tissue transfer and these often extensive bone and soft tissue resections can occasionally be compounded by the presence of a deep venous thrombosis (DVT). We describe two patients in whom free tissue transfer was attempted, following extensive resection of a sarcoma in the thigh. Both patients had been diagnosed with DVT prior to surgery and received therapeutic low molecular weight heparin preoperatively. In the first patient, flap failure occurred due to venous congestion initially resulting from poor flow in the reconstructed femoral vein and then thrombosis and failure of the vascular reconstruction. In the second patient the superficial venous system was used for successful microvascular anastomosis leading to survival of the flap. Therefore, patients undergoing lower extremity free tissue transfer who are at high risk of DVT, or when there is a clinical suspicion of DVT, thorough preoperative assessment of the deep and superficial venous system is warranted for reconstruction planning.
authors.affiliation: Division of Plastic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Dylan J
authors.initials: DJ
authors.lastname: Murray
authors.forename: Peter C
authors.initials: PC
authors.lastname: Neligan
authors.forename: Christine B
authors.initials: CB
authors.lastname: Novak
authors.forename: Brent
authors.initials: B
authors.lastname: Howley
authors.forename: Jay S
authors.initials: JS
authors.lastname: Wunder
authors.forename: Joan E
authors.initials: JE
authors.lastname: Lipa
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery; D005260:Female; D006084:Graft Rejection; D051677:Histiocytoma, Malignant Fibrous / Q000601:surgery; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000601:surgery; D012516:Osteosarcoma / Q000601:surgery; D011183:Postoperative Complications; D011300:Preoperative Care / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods; D013524:Surgical Flaps / Q000098:blood supply*; D020246:Venous Thrombosis / Q000209:etiology*