title: Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.
abstract: A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.
authors.affiliation: Gustaf H. Carlson School of Chemsitry and Biochemistry, Clark University , Worcester, Massachusetts 01610, USA.
authors.forename: Mary R
authors.initials: MR
authors.lastname: Brennan
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Costello
authors.forename: Simin D
authors.initials: SD
authors.lastname: Maleknia
authors.forename: George R
authors.initials: GR
authors.lastname: Pettit
authors.forename: Karen L
authors.initials: KL
authors.lastname: Erickson
mesh_terms: D000818:Animals; D015394:Molecular Structure; D010219:Papua New Guinea; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification*; D011161:Porifera / Q000737:chemistry*; D011392:Proline / Q000737:chemistry
chemical_list: D010456:Peptides, Cyclic; C529038:stylopeptide 2; D011392:Proline