[Characteristics of the bile-acid spectrum of the bile and duodenal content in mice in drug-induced hepatitis and during correction therapy].
Medicamentous hepatitis in mice is accompanied by infringement of synthetic, conjugative and eliminative liver functions. It is experimentally proved, that chemical composition of bile and duodenal contents may be corrected by including drugs with reparation actions in the rehabilitation circuit, in particular those made on the basis of phospholipids of various origin: biologically active additive FLP-MD and preparation "Essentiale".
Hryshchenko
V A
VA
Lytvynenko
O M
OM
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D001646:Bile / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000032:analysis*; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D002855:Chromatography, Thin Layer; D004008:Diclofenac / Q000009:adverse effects; D019587:Dietary Supplements; D004386:Duodenum / Q000378:metabolism*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001647:Bile Acids and Salts; D010713:Phosphatidylcholines; C011246:essential 303 forte; D004008:Diclofenac