title: Primary thyroid-like papillary adenocarcinoma of the nasopharynx.
abstract: Thyroid-like papillary adenocarcinoma is an extremely rare neoplasm in the nasopharynx. We present a case with a pedunculated tumor in the nasopharyngeal vault and the preoperative biopsy revealed a thyroid-like papillary adenocarcinoma. Complete tumor resection via modified facial translocation was undergone subsequently. Postoperative histopathological examinations and immunohistochemical studies confirmed the diagnosis. Regarding the association with Epstein-Barr virus (EBV), the tumor was negative for both small EBV-encoded RNA (EBER) and EBV latent membrane protein-1 (LMP-1) oncogene. This rare neoplasm demonstrated a distinct etiology and nature from typical nasopharyngeal carcinomas and should be managed mainly by surgical resection.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Taiwan.
authors.forename: Chia-Hsiang
authors.initials: CH
authors.lastname: Fu
authors.forename: Kai-Ping
authors.initials: KP
authors.lastname: Chang
authors.forename: Shir-Hwa
authors.initials: SH
authors.lastname: Ueng
authors.forename: Chia-Chen
authors.initials: CC
authors.lastname: Wu
authors.forename: Sheng-Po
authors.initials: SP
authors.lastname: Hao
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D004724:Endoscopy; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009305:Nasopharynx / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed