A new method of selective intra-arterial infusion therapy via the superficial temporal artery for head and neck cancer.
OBJECTIVE
We proposed a new selective intra-arterial infusion method via the superficial temporal artery for preventing dislocation of the catheter.


METHODS
This study included 92 patients who were treated by this combination therapy between May 1999 and December 2004. Primary tumor sites included the tongue in 73 patients, base of the tongue in 6 patients, floor of mouth in 4 patients, buccal mucosa in 4 patients, and other sites in 5 patients. Seventy-three patients had untreated lesions and 19 patients had recurrent lesions. Under fluoroscopy, a catheter was inserted into the target artery through the superficial temporal artery using a catheter exchange method.


RESULTS
In 76 (83%) of 92 patients, a catheter was successfully inserted into the target artery. In 4 patients, the catheter fell out of the selected artery during treatment.


CONCLUSIONS
This selective intra-arterial method will be an important modality for advanced tongue cancer.
Fuwa
Nobukazu
N
Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan. nfuwa@aichi-cc.jp
Kodaira
Takeshi
T
Furutani
Kazuhisa
K
Tachibana
Hiroyuki
H
Nakamura
Tatsuya
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001918:Brachytherapy; D016190:Carboplatin / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D015641:Radiography, Interventional / Q000295:instrumentation / Q000379:methods*; D018714:Radiotherapy, Adjuvant; D013699:Temporal Arteries; D014062:Tongue Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy
D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; C053989:nedaplatin; D016190:Carboplatin; D005472:Fluorouracil