title: An electrochemical approach for the detection of HIV-1 protease.
abstract: An electrochemical biosensor with a new bioorganometallic approach for the detection of human immunodeficiency virus (HIV) type 1 protease (HIV-1 PR) using surface-bound ferrocenoyl (Fc)-pepstatin conjugates is presented.
authors.affiliation: Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan, S7N 5C9, Canada.
authors.forename: Kagan
authors.initials: K
authors.lastname: Kerman
authors.forename: Khaled A
authors.initials: KA
authors.lastname: Mahmoud
authors.forename: Heinz-Bernhard
authors.initials: HB
authors.lastname: Kraatz
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D016333:HIV Protease / Q000032:analysis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D000075163:Metallocenes; D008968:Molecular Conformation; D010436:Pepstatins / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D005296:Ferrous Compounds; D000075163:Metallocenes; D010436:Pepstatins; D006046:Gold; D016333:HIV Protease; C514803:p16 protease, Human immunodeficiency virus 1; C004998:ferrocene; C031375:pepstatin