[Impact of subclinical hypothyroidism in cardiopulmonary response during effort and its recovery].
In order to identify the characteristics of subclinical hypothyroidism (SH) during physical stress and its recovery, 15 SH patients and 16 healthy women were compared by a treadmill cardiopulmonary test. Means of variables were analyzed by the Mann-Whitney U test. Patients obtained lower values for peak expired fraction of O2 (14.90+/-1.05 x 16+/-1.14%; p = 0.014); systolic blood pressure variation (34.33+/-17.92 x 52.50+/-17.22; p = 0.009); exercise duration (8.83+/-2.91 x 14.5+/-5.63 min; p = 0.0005), maximal test load (11.6+/-4.22 x 18.94+/-5.45%; p = 0.0004), as well as tendencies in gas exchange ratio and peak heart rate. Between the first and the third recovery minutes, there was a reduction of only 0.71 mmHg in the diastolic blood pressure, whereas there was a 5.33-mmHg reduction to control group (p = 0.0009) (slower recovery of patients). It is presumable that SH may cause cardiopulmonary dysfunctions, with higher sensibility to the parameters previously cited.
Mainenti
Míriam R M
MR
Programa de Pós-Graduação em Endocrinologia, Escola de Educação Física e Desportos (Laboratório de Fisiologia do Exercício), Universidade Federal do Rio de Janeiro, RJ. miriam.mainenti@hotmail.com
Teixeira
Patrícia F S
PF
Oliveira
Fátima P
FP
Vaisman
Mário
M
D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007037:Hypothyroidism / Q000503:physiopathology*; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D018709:Statistics, Nonparametric