[Melkersson-Rosenthal syndrome treated with clofazimine].
Melkersson-Rosenthal syndrome (MRS) is a triad of facial palsy, lingua plicata and chronic orofacial swelling. Mono- and oligosymptomatic forms are common and cheilitis granulomatosa is often considered a monosymptomatic form of MRS. In advanced stages the histological findings are noncaseating granulomas. The etiology remains unclear and treatment is difficult. A few uncontrolled studies have shown corticosteroids and clofazimine to be effective. We report on a 31 year-old man with complete MRS who responded well to treatment with clofazimine.
Bygum
Anette
A
Dermato-venerologisk Afdeling I, Odense Universitetshospital, DK-5000 Odense C. anette.bygum@ouh.fyns-amt.dk.
Toft-Petersen
Marie
M
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002991:Clofazimine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000188:drug therapy*; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002991:Clofazimine