The MMP2 rs243865-T allele is not a major genetic factor for rheumatoid arthritis in the French Caucasian population.
The MMP2 rs243865-T allele was recently suggested to be associated with rheumatoid arthritis (RA) in a case-control study. MMP2 is a positional RA candidate gene. Our aim was to test rs243865 in a French family based study. No significant result was shown. The MMP2 rs243865-T allele is not a major rheumatoid arthritis genetic factor in this population.
Jacq
L
L
GenHotel-EA3886, Evry-Paris VII Universities, Evry-Genopole Cedex, France. laurent@polyarthrite.net
Teixeira
V H
VH
Garnier
S
S
Petit-Teixeira
E
E
Cornélis
F
F
D000483:Alleles; D001172:Arthritis, Rheumatoid / Q000235:genetics*; D005260:Female; D005602:France; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D020778:Matrix Metalloproteinase 2 / Q000235:genetics*; D044465:White People
C522361:MMP2 protein, human; D020778:Matrix Metalloproteinase 2