title: Midcycle pericoital intravaginal bee honey and royal jelly for male factor infertility.
abstract: OBJECTIVE
  To evaluate the efficacy of pericoital intravaginal applications of a mixture of Egyptian bee honey and royal jelly (H/RJ) in the midcycle for the treatment of infertility due to asthenozoospermia.
  
  
  METHODS
  Sohag University Hospital and Asyut Gynecology and Infertility Clinic conducted a crossover study of 99 couples affected by asthenozoospermia. One group used midcycle pericoital vaginal applications of H/RJ and the other underwent a standard intrauterine insemination (IUI) procedure, for 3 cycles or until conception occurred for both groups. After a washout period of 2 months, the couples for whom no pregnancy occurred were crossed over.
  
  
  RESULTS
  A total of 553 cycles were analyzed. There were 23 (8.1%) and 7 (2.6%) pregnancies per cycle, respectively, in the H/RJ and the IUI groups, and the difference was statistically significant (P<0.001).
  
  
  CONCLUSIONS
  Using H/RJ intravaginally might be a simple and reasonably effective method of treating asthenozoospermia.
authors.affiliation: Department of Gynecology and Obstetrics, Sohag University Hospital, Sohag University, Egypt. ahmedahafiz_obs@yahoo.com
authors.forename: Ahmed T
authors.initials: AT
authors.lastname: Abdelhafiz
authors.forename: Jehan A
authors.initials: JA
authors.lastname: Muhamad
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D053627:Asthenozoospermia / Q000628:therapy*; D003075:Coitus; D018592:Cross-Over Studies; D005227:Fatty Acids / Q000008:administration & dosage*; D005260:Female; D006722:Honey; D006801:Humans; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted; D000099219:Royal Jelly
chemical_list: D005227:Fatty Acids; D000099219:Royal Jelly