[Clinical study on treatment of chronic simple lichen by Qiangyue Cream].
OBJECTIVE
To explore the efficacy and safety of Qiangyue Cream (QYC) for treatment of chronic simple lichen (CSL).


METHODS
A randomized, double-blinded, parallel controlled clinical trial was performed in 80 patients with CSL allocated in two groups, the 40 locally treated with QYC as the tested group, and the 40 treated with halometasone cream as the control group, with the treatment lasted for 2 successive weeks.


RESULTS
A better effect in improving the scores of clinical symptoms, degree of itching and lichenoid change was shown in the tested group than that in the control group (P < 0.05), but insignificant difference was found between the two groups in the cure rate and the total effective rate. The occurrence of adverse reaction in both groups was in 1 case.


CONCLUSIONS
QYC is a safe and effective external drug for CSL treatment, its efficacy might approach that of halometasone cream, with a better effect for relieving itching and milder adverse reactions.
Zhang
Xu
X
Department of Dermatology, Huaian First Hospital Affiliated to Nanjing Medical University, Jiangsu. hapfkyszhx@sina.com
Sun
Wei-Guo
WG
Sun
Jun
J
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D008517:Phytotherapy; D016896:Treatment Outcome; D055815:Young Adult
D004365:Drugs, Chinese Herbal; D009824:Ointments; C533466:qiangyue