1-year follow-up of autologous muscle-derived stem cell injection pilot study to treat stress urinary incontinence.
We hereby report a 1-year follow-up on eight women in the first North America trial in which stress urinary incontinence (SUI) was treated with muscle-derived stem cell injections. Mean and median follow-up in this group was 16.5 and 17 months (range 3-24 months). Improvement in SUI was seen in five of eight women, with one achieving total continence. Onset of improvement was between 3 and 8 months after injection. Cure or improvement continued at a median of 10 months. No serious adverse events were reported.
Carr
L K
LK
Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.
Steele
D
D
Steele
S
S
Wagner
D
D
Pruchnic
R
R
Jankowski
R
R
Erickson
J
J
Huard
J
J
Chancellor
M B
MB
D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D032446:Myoblasts / Q000637:transplantation*; D010865:Pilot Projects; D033581:Stem Cell Transplantation; D014182:Transplantation, Autologous; D014550:Urinary Incontinence, Stress / Q000628:therapy*