title: Patterns of fatigue and its correlates over the first 2 years after traumatic brain injury.
abstract: This study used a prospective longitudinal design to quantify fatigue and associated factors during the first 2 years after traumatic brain injury (TBI). Fifty-one individuals were assessed at 3 time points: within the first 6, 12, and 18-24 months after TBI. Self-reported fatigue improved during the first year, as did pain, sleep quality, cognitive independence, and involvement in productive activity. Further changes up to 2 years after TBI were not observed. The subset of individuals who reported significant increases in fatigue over the first 2 years demonstrated poorer outcomes in cognition, motor symptoms, and general functioning than those with decreased or stable fatigue.
authors.affiliation: Rehabilitation Research Center, Santa Clara Valley Medical Center, San Jose, Calif 95128, USA. tamara@tbi-sci.org
authors.forename: Tamara
authors.initials: T
authors.lastname: Bushnik
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Englander
authors.forename: Jerry
authors.initials: J
authors.lastname: Wright
mesh_terms: D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003072:Cognition Disorders / Q000209:etiology; D005221:Fatigue / Q000209:etiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D010146:Pain / Q000209:etiology; D011446:Prospective Studies; D012893:Sleep Wake Disorders / Q000209:etiology; D013997:Time Factors