title: The repair effects of Achyranthes bidentata extract on the crushed common peroneal nerve of rabbits.
abstract: In this study the effect of the Achyranthes bidentata root aqueous extract on regeneration of the crushed common peroneal nerve in rabbits by using a combination of electrophysiological assessment and histological aspect were investigated. The examined functional and morphological parameters suggest that A. bidentata extract could accelerate peripheral nerve regeneration in a dose-dependent manner (10-20 microg/kg, i.v.).
authors.affiliation: Jiangsu Key Laboratory of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong, JS 226001, PR China. shengdd@public.nt.js.cn
authors.forename: Fei
authors.initials: F
authors.lastname: Ding
authors.forename: Qiong
authors.initials: Q
authors.lastname: Cheng
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Gu
mesh_terms: D029044:Achyranthes; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D003444:Crush Syndrome / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D004594:Electrophysiology; D007262:Infusions, Intravenous; D009416:Nerve Regeneration / Q000187:drug effects*; D010543:Peroneal Nerve / Q000293:injuries* / Q000503:physiopathology / Q000648:ultrastructure; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D011817:Rabbits
chemical_list: D000700:Analgesics; D010936:Plant Extracts