Acute eosinophilic pneumonia with intramuscular progesterone after in vitro fertilization.
OBJECTIVE
To report an unusual case of acute eosinophilic pneumonia that was associated with IM P in oil after IVF.


METHODS
Case report.


METHODS
Academic teaching hospital.


METHODS
A 35-year-old primigravid female who developed acute eosinophilic pneumonia after administration of IM P in oil as luteal-phase support after IVF.


METHODS
Corticosteroid therapy; replacement of IM P with intravaginal preparation.


METHODS
Evaluation of blood eosinophil counts along with clinical symptoms and chest radiograph findings at initial presentation and throughout the hospital course.


RESULTS
After the noted interventions, there was a marked improvement of clinical symptoms, chest radiograph findings, and eosinophilia.


CONCLUSIONS
Although allergic reactions to IM P-in-oil administration are exceedingly rare, clinicians caring for patients using these products should be aware of potential adverse reactions and subsequent management.
Khan
Amir M
AM
Department of Pulmonary Medicine, Pulmonary and Critical Care Center, Bronx, New York 10463, USA. dramirkhan@hotmail.com
Jariwala
Sunit
S
Lieman
Harry Jay
HJ
Klapper
Philip
P
D000208:Acute Disease; D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D007273:Injections, Intramuscular; D011374:Progesterone / Q000009:adverse effects*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis*
D011374:Progesterone