[Successful treatment of primary peritoneal carcinoma with paclitaxel and carboplatin combination chemotherapy].
BACKGROUND
A standard treatment for primary peritoneal carcinoma has not been established to date. We report three patients with primary peritoneal carcinoma who were successfully treated with paclitaxel and carboplatin combination chemotherapy.


METHODS
Three patients, 66-, 73-, and 71-year-old women who presented with abdominal swelling, were referred to our hospital. Following detailed physical examination, they underwent exploratory laparotomy and were diagnosed with primary peritoneal carcinoma. Postoperatively, the sole treatment was comprised of combination chemotherapy of paclitaxel and carboplatin following which the tumor marker(CA125)levels normalized. Moreover, there was no evidence of tumors on CT scan, and the patients showed good recovery.


CONCLUSIONS
Paclitaxel and carboplatin combination chemotherapy are effective for treatment of primary peritoneal carcinoma and can be considered one of the medical treatment options.
Tohya
Toshimitsu
T
Dept. of Obstetrics and Gynecology, Kumamoto Rosai Hospital.
Ujioka
Takeshi
T
Yamaguchi
Munekage
M
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage / Q000627:therapeutic use*; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
D016190:Carboplatin; D017239:Paclitaxel