Advances in the understanding of allergic asthma.
This article reviews the concept of airway remodeling, through various inflammatory cells, the roles of angiogenesis, vascular endothelial cell growth factor, respiratory syncytial virus, and other biomarkers, including exhaled nitric oxide. Control of allergic asthma using immunomodulation and other strategies is addressed.
Frieri
Marianne
M
Division of Allergy and Immunology, Nassau University Medical Center, North Shore University-Long Island Jewish Health Care System, State University of New York, Stony Brook, New York 11554, USA. mfrieri@numc.edu
D000485:Allergens / Q000276:immunology* / Q000378:metabolism; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D001249:Asthma / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism / Q000821:virology; D019819:Budesonide / Q000627:therapeutic use; D016207:Cytokines / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007155:Immunologic Factors / Q000276:immunology / Q000378:metabolism; D018836:Inflammation Mediators / Q000276:immunology / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D000069444:Omalizumab; D018357:Respiratory Syncytial Virus Infections / Q000276:immunology; D012136:Respiratory Syncytial Viruses / Q000276:immunology; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
D000485:Allergens; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D016207:Cytokines; D007155:Immunologic Factors; D018836:Inflammation Mediators; D042461:Vascular Endothelial Growth Factor A; D000069444:Omalizumab; D009569:Nitric Oxide; D007073:Immunoglobulin E; D019819:Budesonide