title: Aneurysmal bone cyst recurrence in children: a review of 56 patients.
abstract: BACKGROUND
  Aneurysmal bone cysts (ABCs) are benign lesions that are usually treated with intralesional procedures. The clinical behavior of ABCs is reported to be more aggressive in younger patients, with high recurrence rates after surgical treatment by several authors. The purpose of this study was to review longitudinally the demographic data and outcome of current surgical techniques in children with ABC treated at a single institution and to determine the possible risk factors for recurrence, which may be detected at initial examination, including age, presenting complaint, and radiological characteristics.
  
  
  METHODS
  The authors performed a retrospective, pediatric population-based (< or =16 years) analysis of 56 cases of ABCs with more than 2 years' follow-up. The subjects were studied and classified on the basis of their age group (< or =5, 5-10, and >10 years of age). The possible risk factors for recurrence were analyzed initially with Student t test and Pearson chi2 test, then a logistic regression analysis model was used for multivariate analysis.
  
  
  RESULTS
  Nine patients were younger than 5 years, 17 were between 5 and 10 years old, and 30 were older than 10 years. The most frequent location of the lesion was the humerus (11 cases) followed by proximal femur and fibula. Curettage was the most common treatment modality followed by resection. Recurrence of the lesion occurred in 5 children in the younger age group and in 4 children in the older age group. The difference in persistence or recurrence rates based on age (< or =5 years) and previous surgery was statistically significant. In addition, we have found no significant implication of physeal contact and size of the lesion on recurrence.
  
  
  CONCLUSIONS
  The recurrence rates of primary ABC seemed to be higher in younger children. Considering the high cure rates with intralesional procedures even after recurrence, we suggest less aggressive intralesional procedures even in patients with mentioned risk factors; however, the patients' family should be informed about the high probability of recurrence.
authors.affiliation: Department of Orthopedics and Traumatology, Ankara University Medicine Faculty, Ankara, Turkey.
authors.forename: Kerem
authors.initials: K
authors.lastname: Başarir
authors.forename: Ahmet
authors.initials: A
authors.lastname: Pişkin
authors.forename: Berk
authors.initials: B
authors.lastname: Güçlü
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yildiz
authors.forename: Yener
authors.initials: Y
authors.lastname: Sağlik
mesh_terms: D000293:Adolescent; D017824:Bone Cysts, Aneurysmal / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome