title: [Experience with high-flow nasal cannula oxygen therapy in children].
abstract: OBJECTIVE
  To analyze the efficacy of a high-flow oxygen therapy system in children with moderate respiratory failure and/or high oxygen requirements.
  
  
  METHODS
  We performed a prospective, observational clinical study of patients treated with a high-flow oxygen therapy system via nasal cannulae. The following variables were analyzed: clinical severity score, respiratory rate, heart rate, clinical improvement, oxygen saturation, blood gases, complications, and the need for ventilation after starting the treatment.
  
  
  RESULTS
  Eighteen treatments were studied in 16 patients (two girls and 14 boys) aged between 2 and 156 months. With the high-flow oxygen therapy system, respiratory rate slightly decreased from 34.5 bpm to 32.2 bpm (p<0.04) and O2 saturation increased from 90.2% to 93.5% (p<0.02). Fourteen patients showed a clinical improvement and/or tolerated the change from the previous respiratory assistance. The duration of treatment was 3 days (range: 6 hours to 25 days). Mild complications (initial irritability and excessive humidity) were observed in two patients, but treatment interruption was not required. No secondary respiratory tract infections were observed. The system was withdrawn in four patients, due to lack of improvement in two patients, deterioration after initial improvement in one patient, and failure of the system's temperature regulation in one patient.
  
  
  CONCLUSIONS
  The high-flow oxygen therapy system is effective in a large percentage of children with high oxygen requirements and/or moderate respiratory failure.
authors.affiliation: Sección de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Urbano Villaescusa
authors.forename: S
authors.initials: S
authors.lastname: Mencía Bartolomé
authors.forename: E
authors.initials: E
authors.lastname: Cidoncha Escobar
authors.forename: J
authors.initials: J
authors.lastname: López-Herce Cid
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Santiago Lozano
authors.forename: A
authors.initials: A
authors.lastname: Carrillo Alvarez
mesh_terms: D000293:Adolescent; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000628:therapy*