title: Successful salvage treatment of disseminated cutaneous fusariosis with liposomal amphotericin B and terbinafine after allogeneic stem cell transplantation.
abstract: Fusarium infections are associated with high mortality after allogeneic stem cell transplantation. We report on successful treatment of a disseminated cutaneous Fusarium proliferatum infection using liposomal amphotericin B and terbinafine. In vitro susceptibility tests of antifungal drugs suggest that terbinafine is a potent additional antifungal drug for disseminated cutaneous fusariosis.
authors.affiliation: Department of Hematology and Oncology, Charité University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany. stefan.neuburger@charite.de
authors.forename: S
authors.initials: S
authors.lastname: Neuburger
authors.forename: G
authors.initials: G
authors.lastname: Massenkeil
authors.forename: M
authors.initials: M
authors.lastname: Seibold
authors.forename: C
authors.initials: C
authors.lastname: Lutz
authors.forename: I
authors.initials: I
authors.lastname: Tamm
authors.forename: P
authors.initials: P
authors.lastname: le Coutre
authors.forename: B
authors.initials: B
authors.lastname: Graf
authors.forename: B
authors.initials: B
authors.lastname: Doerken
authors.forename: R
authors.initials: R
authors.lastname: Arnold
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology; D004359:Drug Therapy, Combination; D005260:Female; D005670:Fusarium / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D009503:Neutropenia / Q000150:complications; D016879:Salvage Therapy; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D000077291:Terbinafine; D014184:Transplantation, Homologous / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; C068538:liposomal amphotericin B; D000666:Amphotericin B; D000077291:Terbinafine