[Polarization and asymmetric division of stem cells].
Asymmetric cell division observed in many groups of organisms has similar mechanisms suggesting conservatism of the process. Asymmetric division of stem cells that reside in their niches is aimed to regulation of cell proliferation and genome stability maintenance. But stem cells may also divide symmetrically depending on situation. Alteration of mechanisms of asymmetric division might be one of the factors of neoplasm growth.
Terskikh
V V
VV
Vasil'ev
A V
AV
Voroteliak
E A
EA
D000818:Animals; D002455:Cell Division; D019070:Cell Lineage; D016764:Cell Polarity; D006801:Humans; D014411:Neoplastic Stem Cells / Q000473:pathology; D013234:Stem Cells / Q000166:cytology* / Q000473:pathology / Q000502:physiology*