title: Influence of esophageal motility on the outcome of laparoscopic total fundoplication.
abstract: The aim of this study is to evaluate if esophageal dysmotility can influence the outcome of laparoscopic total fundoplication for gatro-esophageal reflux disease (GERD). The advent of laparoscopic fundoplication has greatly reduced the morbidity of antireflux surgery and by now, it should be considered the surgical treatment of choice for GERD. Some authors assert that total versus partial fundoplication should improve the rate of postoperative dysphagia or gas bloat syndrome, particularly in patients with esophageal dysmotility. From September 1992 to December 2005, 420 consecutive patients 171 male and 249 female, mean age 42.8 years (range 12-80) underwent laparoscopic Nissen-Rossetti fundoplication. At manometric evaluation, we divided patients into two groups: group A (163/420; 38.8%) with impaired esophageal peristalsis (peristaltic waves with a pressure < 30 mmHg), and group B (257/420; 61.2%) without impaired peristalsis. We followed up clinically 406 out of 420 (96.7%) patients, 156/163 patients (95.7%) in group A and 250/257 patients (97.3%) in group B. An excellent outcome was observed in 143/156 (91.7%) group A patients and in 234/250 (93.6%) group B patients (P = NS). Both groups showed significant improvement in clinical symptom score with no statistically significant difference between patients with normal and impaired peristalsis. Thus, preoperative defective esophageal peristalsis is not a contraindication to total laparoscopic fundoplication.
authors.affiliation: I Division of Surgery, Second University of Naples, Naples, Italy. francesco_pizza@libero.it
authors.forename: F
authors.initials: F
authors.lastname: Pizza
authors.forename: G
authors.initials: G
authors.lastname: Rossetti
authors.forename: G
authors.initials: G
authors.lastname: Rosetti
authors.forename: G
authors.initials: G
authors.lastname: Del Genio
authors.forename: V
authors.initials: V
authors.lastname: Maffettone
authors.forename: L
authors.initials: L
authors.lastname: Brusciano
authors.forename: A
authors.initials: A
authors.lastname: Del Genio
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D050782:Esophageal pH Monitoring; D004941:Esophagitis / Q000601:surgery; D004947:Esophagus / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008365:Manometry; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010528:Peristalsis / Q000502:physiology*; D012720:Severity of Illness Index