title: Fatal coxsackievirus A-16 pneumonitis in adult.
abstract: Coxsackievirus A-16 (CVA-16) is the agent of hand, foot, and mouth disease in children. We report a case of fatal pneumonitis in an adult due to a CVA-16 strain with a low (78.6%) rate of sequence homology with the reference strain. A modified, more virulent, strain of CVA-16 could be emerging.
authors.affiliation: Centre Hospitalier Universitaire Pontchaillou, Rennes, France.
authors.forename: François
authors.initials: F
authors.lastname: Legay
authors.forename: Nicolas
authors.initials: N
authors.lastname: Lévêque
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gacouin
authors.forename: Pierre
authors.initials: P
authors.lastname: Tattevin
authors.forename: Julien
authors.initials: J
authors.lastname: Bouet
authors.forename: Rémi
authors.initials: R
authors.lastname: Thomas
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Chomelt
mesh_terms: D000368:Aged; D003384:Coxsackievirus Infections / Q000175:diagnosis / Q000821:virology*; D029821:Enterovirus A, Human / Q000145:classification / Q000302:isolation & purification*; D017809:Fatal Outcome; D005602:France; D006232:Hand, Foot and Mouth Disease / Q000175:diagnosis / Q000821:virology*; D006801:Humans; D008297:Male; D010802:Phylogeny; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000821:virology*; D016133:Polymerase Chain Reaction