title: Rocky Mountain spotted fever, Panama.
abstract: We describe a fatal pediatric case of Rocky Mountain spotted fever in Panama, the first, to our knowledge, since the 1950s. Diagnosis was established by immunohistochemistry, PCR, and isolation of Rickettsia rickettsii from postmortem tissues. Molecular typing demonstrated strong relatedness of the isolate to strains of R. rickettsii from Central and South America.
authors.affiliation: Hospital del Niño, Panama City, Panama.
authors.forename: Dora
authors.initials: D
authors.lastname: Estripeaut
authors.forename: María Gabriela
authors.initials: MG
authors.lastname: Aramburú
authors.forename: Xavier
authors.initials: X
authors.lastname: Sáez-Llorens
authors.forename: Herbert A
authors.initials: HA
authors.lastname: Thompson
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Dasch
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Paddock
authors.forename: Sherif
authors.initials: S
authors.lastname: Zaki
authors.forename: Marina E
authors.initials: ME
authors.lastname: Eremeeva
mesh_terms: D000818:Animals; D001483:Base Sequence; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008969:Molecular Sequence Data; D010176:Panama / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D012284:Rickettsia rickettsii / Q000235:genetics / Q000302:isolation & purification*; D012373:Rocky Mountain Spotted Fever / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy