title: A comparative study of the transhiatal laparoscopic approach versus laparoscopic gastric mobilisation and right open transthoracic esophagectomy for esophageal cancer management.
abstract: OBJECTIVE
  Regarding the surgical treatment of esophageal cancer, a question was raised by the introduction of minimally invasive surgery, because of the technical complexity of the techniques involved and its uncertain benefits. We evaluated the impact of laparoscopic esophagectomy on the surgical approach to esophageal cancer.
  
  
  METHODS
  From January 2002 to March 2006, 22 non-randomized patients were recruited to undergo esophagectomy for neoplastic disease. The esophagectomy and esophagogastroplasty were performed using the laparoscopic transhiatal technique (THE) in 9 cases, while a combined laparoscopic gastric mobilisation and right transthoracic incision (TT/LE) was performed in the other 13.
  
  
  RESULTS
  Mean follow up was 21+/-3.23 months, range 2-46 months. Overall cumulative survival was 84.0% at 12 months, 61.3% at 24 months, 51.0% at 36 months. THE achieved better results than TT/LE on the ground with regard to the time it took to complete the procedure (p=0.046) and the hospital stay times (p=0.039), and the time in ICU, postoperative oral feeding resumption, number of retrieved lymph nodes.
  
  
  CONCLUSIONS
  The clinical benefits of minimally invasive techniques regard the time it takes to complete the procedure, the time in ICU, postoperative oral feeding resumption and the hospital stay times. Minimally invasive surgery might be not less curative and effective than open surgical procedures, as found in our small non-randomzed series of patients. Larger series should confirm these results.
authors.affiliation: Department of General Surgery, School of Medicine, University of Udine, Italy, 33100 Udine, Italy. enricobenzoni@gmail.com
authors.forename: Enrico
authors.initials: E
authors.lastname: Benzoni
authors.forename: Giovanni
authors.initials: G
authors.lastname: Terrosu
authors.forename: Vittorio
authors.initials: V
authors.lastname: Bresadola
authors.forename: Alessandro
authors.initials: A
authors.lastname: Uzzau
authors.forename: Sergio
authors.initials: S
authors.lastname: Intini
authors.forename: Luigi
authors.initials: L
authors.lastname: Noce
authors.forename: Carla
authors.initials: C
authors.lastname: Cedolini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Bresadola
authors.forename: Dino
authors.initials: D
authors.lastname: De Anna
mesh_terms: D000368:Aged; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D015391:Gastroplasty / Q000379:methods*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000473:pathology; D009367:Neoplasm Staging; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D013908:Thoracotomy / Q000379:methods*; D016896:Treatment Outcome