[A case of squamous cell carcinoma of esophagus with mediastinal lymph node recurrence after surgical resection treated with systemic chemotherapy and chemoradiotherapy].
The patient was a 58-year-old man with a mediastinal lymph node recurrence 26 months after surgical resection of squamous cell carcinoma of esophagus. We started a treatment with systemic chemotherapy (FAP chemotherapy) on the supposition of systemic recurrence. Next, chemoradiotherapy with docetaxel (DOC) was chosen for the expectation of powerful local control. Then bi-weekly DOC chemotherapy was chosen for the third-line therapy at an outpatient clinic. A complete response (CR) was observed after the sixth course and the treatment was finished at the twelfth course. CT showed CR after the treatment for six months. The prognosis of the cases with post-operative recurrences was poor, and its formation of recurrence varied. The strategy of the treatment should be considered a case-by-case.
Matsuyama
Jin
J
Dept. of Surgery, Yao Municipal Hospital.
Fukushima
Yukio
Y
Hashimoto
Kazuhiko
K
Morita
Shunji
S
Morimoto
Takashi
T
Nishishou
Isamu
I
Sasaki
Yo
Y
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed