Lipid abnormalities and cardiovascular risk in the elderly.
The relationship between dyslipidaemia and cardiovascular disease is well documented. However, it is relevant to consider that cholesterol levels vary with age. Moreover, there is some controversy regarding the ability of lipid levels to predict vascular risk beyond the age of 70 years. In general, raised low-density lipoprotein cholesterol (LDL-C) and triglyceride levels as well as reduced levels of high-density lipoprotein cholesterol (HDL-C) predict risk in the elderly. There is evidence supporting the use of statins in the elderly. It is also likely that these drugs are under-used in this population.
Milionis
Haralampos J
HJ
Elisaf
Moses S
MS
Mikhailidis
Dimitri P
DP
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000097:blood* / Q000209:etiology* / Q000517:prevention & control; D008076:Cholesterol, HDL / Q000187:drug effects; D008078:Cholesterol, LDL / Q000187:drug effects; D050171:Dyslipidemias / Q000097:blood* / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors