title: Biliary complications after liver transplantation from maastricht category-2 non-heart-beating donors.
abstract: BACKGROUND
  There are unresolved issues regarding the security of liver transplantation with non-heart-beating donors (NHBDs). Recently, an increased incidence of biliary complications, mainly intrahepatic ischemic-type biliary strictures, has been described after controlled NHBDs.
  
  
  METHODS
  We studied the incidence and risk factors for biliary complications among uncontrolled NHBDs recipients compared with a large population of HBD recipients.
  
  
  RESULTS
  Overall, 16.8% of patients in the HBD group and 41.7% of patients in the NHBD group suffered any type of biliary complication (P=0.66). However, the incidence of nonanastomotic biliary strictures was significantly greater in the NHBD group (P<0.001). Multivariate analysis showed that independent risk factors for nonanastomotic strictures were hepatic artery thrombosis (relative risk; 98.7) and receiving a liver from a NHBD (relative risk; 47.1).
  
  
  CONCLUSIONS
  If this type of donors is accepted as a source of liver organs, the high incidence of biliary complications should be considered and efforts should be made to decrease ischemic injury.
authors.affiliation: Liver Transplant Unit, Hospital Juan Canalejo, Xubias de Arriba, A Coruña.
authors.forename: Francisco
authors.initials: F
authors.lastname: Suárez
authors.forename: Alejandra
authors.initials: A
authors.lastname: Otero
authors.forename: Miguel
authors.initials: M
authors.lastname: Solla
authors.forename: Francisco
authors.initials: F
authors.lastname: Arnal
authors.forename: Maria Jose
authors.initials: MJ
authors.lastname: Lorenzo
authors.forename: Milagros
authors.initials: M
authors.lastname: Marini
authors.forename: José L
authors.initials: JL
authors.lastname: Vázquez-Iglesias
authors.forename: Manuel
authors.initials: M
authors.lastname: Gómez
mesh_terms: D000328:Adult; D000368:Aged; D002780:Cholestasis, Intrahepatic / Q000209:etiology*; D006085:Graft Survival; D006323:Heart Arrest; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000145:classification*