title: Schizophrenia and beta-thalassemia: a genetic link?
abstract: This report of two cases in which schizophrenia and beta-thalassemia occurred simultaneously in several family members may suggest that a genetic link exists between these two disorders. A known genetic disease (beta-thalassemia) could help confirm the presence, on the short arm of chromosome 11, of a genetic susceptibility factor for schizophrenia.
authors.affiliation: University Hospitals of Geneva, Department of Psychiatry, Division of Adult Psychiatry, Rue du 31 Décembre 36, 1207 Geneva, Switzerland. Laurence.Borras@hcuge.ch
authors.forename: Laurence
authors.initials: L
authors.lastname: Borras
authors.forename: Philippe
authors.initials: P
authors.lastname: Huguelet
mesh_terms: D000328:Adult; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000150:complications / Q000235:genetics*; D014365:Tryptophan Hydroxylase / Q000235:genetics*; D017086:beta-Thalassemia / Q000150:complications / Q000235:genetics*
chemical_list: C497467:TPH1 protein, human; D014365:Tryptophan Hydroxylase