title: Use of intranasal corticosteroids in the management of congestion and sleep disturbance in pediatric patients with allergic rhinitis.
abstract: Allergic rhinitis affects a large number of children and exerts a considerable socioeconomic impact. It is underdiagnosed and inadequately treated, which predisposes children to potentially serious comorbidities. Allergic rhinitis symptoms may create nighttime breathing problems and sleep disturbances and have a negative effect on a child's ability to learn in the classroom. Although antihistamines have shown efficacy in relieving many symptoms, they have little effect on nasal congestion. This article summarizes the advantages of intranasal corticosteroids, including their effectiveness against congestion and excellent safety profile. Intranasal corticosteroids with minimal systemic bioavailability provide topical drug delivery that minimizes the potential for systemic side-effects.
authors.affiliation: Division of Immunology, University of North Texas Health Science Center, Fort Worth, Texas 76132, USA. boblaniermd@askdrbob.com
authors.forename: Bob Q
authors.initials: BQ
authors.lastname: Lanier
mesh_terms: D000281:Administration, Intranasal; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D002648:Child; D006801:Humans; D015508:Nasal Obstruction / Q000188:drug therapy*; D012221:Rhinitis, Allergic, Perennial / Q000150:complications*; D012893:Sleep Wake Disorders / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones