Hepatic resection for recurrent metastatic ovarian cancer.
BACKGROUND
The role for liver resection in metastatic ovarian cancer has not been defined. The aim of the current study was to investigate the validity of hepatic resection as a treatment option in metastatic ovarian cancer.


METHODS
Retrospective review of a single institution's experience of patients undergoing hepatic resection for metastatic ovarian cancer from 1998-2006.


RESULTS
Ten patients underwent resection for metastatic ovarian cancer. Primary tumor type included serous cystadenocarcinoma (n = 8), granulosa cell (n = 1), and yolk sac (n = 1). Median disease-free interval was 48 months. Liver resections included trisegmentectomy (n = 4), lobectomy (n = 4), and bisegmentectomy(n = 1). Additional surgeries included diaphragm resection (n = 60), bowel resection, (n = 30), and adrenalectomy (n = 10). The median overall survival following liver resection was 33 months.


CONCLUSIONS
Liver resection for metastatic ovarian cancer is safe and is associated with long-term survival in some patients. Larger analysis may lead to the identification of prognostic factors associated with improved outcomes.
Abood
Gerard
G
Division of Surgical Oncology, Department of Surgery, Loyola University Medical Center, 2160 S. First Ave., Maywood, IL 60153, USA.
Bowen
Matthew
M
Potkul
Ronald
R
Aranha
Gerard
G
Shoup
Margo
M
D000328:Adult; D000368:Aged; D003536:Cystadenocarcinoma / Q000556:secondary / Q000601:surgery; D018240:Endodermal Sinus Tumor / Q000556:secondary / Q000601:surgery; D005260:Female; D006106:Granulosa Cell Tumor / Q000556:secondary / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000556:secondary / Q000601:surgery*; D012189:Retrospective Studies