title: Age-dependent changes of airway obstruction parameters.
abstract: The study was aimed at the assessment of the physiological range of phi and Tme/Te indices in children of up to 24 months of age, as based on noncalibrated respiratory inductive plethysmography performed in the supine position. We also examined the dependence of these indices on children's age and sex. The study was carried out in 127 healthy children. The results of the study indicate a significant decrease of phi in children aged 7-24 months in comparison with children of up to 6 months of age (P<0.001). Similarly, values of Tme/Te were found significantly higher in the group of older children (P<0.05). We did not find any appreciable sex differences in both measured parameters. The results of this study suggest that the Tme/Te index might be more stable, less age-dependent parameter of the Respitrace measurement than the phase angle j, but further research and analysis to achieve a correct verdict are warranted.
authors.affiliation: Clinic of Children and Adolescents, Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia. slavonosal@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Nosal
authors.forename: M
authors.initials: M
authors.lastname: Sutovska
authors.forename: G
authors.initials: G
authors.lastname: Nosalova
authors.forename: P
authors.initials: P
authors.lastname: Banovcin
authors.forename: J
authors.initials: J
authors.lastname: Sutovsky
authors.forename: S
authors.initials: S
authors.lastname: Franova
mesh_terms: D000375:Aging / Q000502:physiology*; D000402:Airway Obstruction / Q000503:physiopathology*; D000465:Algorithms; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010991:Plethysmography / Q000592:standards; D012015:Reference Standards; D015656:Respiratory Mechanics / Q000502:physiology; D012727:Sex Characteristics