title: Secondary Amyloidosis, a Fatal Complication of Behcet's Disease: Three Case Reports.
abstract: Renal amyloidosis (RA) is known to be one of the many complications of Behcet's disease (BD) but its frequency has been often underestimated. In this paper, we report on three cases of RA in a series of 105 patients with BD. RA was clinically suspected in our patients by the presence of edema and/or hypotension. The nephrotic syndrome was present in all of them and one patient had associated renal failure. Renal biopsy showed amyloid deposits type AA in all cases.Our patients received Colchicine at doses of 1 mg per day but with disappointing results. Their prognosis was significantely impaired with our three patients dying at ten years, six months and four weeks after diagnosis of RA. We will try, through this clinical experience and based on the relevant literature to better understand this kind of morbid association.
authors.affiliation: Departments of Nephrology and Internal Medicine, Monastir Hospital, Monastir 5000, Tunisia.
authors.forename: Habib
authors.initials: H
authors.lastname: Skhiri
authors.forename: Silvia
authors.initials: S
authors.lastname: Mahjoub
authors.forename: Olfa
authors.initials: O
authors.lastname: Harzallah
authors.forename: Abdellatif
authors.initials: A
authors.lastname: Achour
authors.forename: Samia
authors.initials: S
authors.lastname: Bouraoui
authors.forename: Ameur
authors.initials: A
authors.lastname: Frih
authors.forename: Nasr Ben
authors.initials: NB
authors.lastname: Dhia
authors.forename: Mezri
authors.initials: M
authors.lastname: El May