[New approaches to brain protection against global ischemia].
Three pathways to increase tolerance to global cerebral ischemia have been worked out: (1) the use of inhibitory neurotransmitters and their analogues; (2) injection of neuroleptics; (3) hypoxic preconditioning. We revealed the importance of receptors, K(ATP) channels and induction of hypothermia in neuroprotective mechanisms of these influences.
Kulinskiĭ
V I
VI
Minakina
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LN
D000818:Animals; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002545:Brain Ischemia / Q000517:prevention & control*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004195:Disease Models, Animal; D019194:Ischemic Preconditioning / Q000379:methods*; D051379:Mice; D018377:Neurotransmitter Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D018377:Neurotransmitter Agents