Low amplitude daily changes in reflex ventilatory response to progressive isocapnic hypoxia.
Daily changes in reflex ventilatory responses to hypoxia were studied in 56 young healthy men participated. A rebreathing technique--progressive isocapnic hypoxia--was used to measure hypoxic chemoreflex reactivity. The measurements were repeated every 3 hours during a 24-hour period. The ventilatory response to hypoxia--analyzed as the relationships (slope) MV/SaO2 (minute ventilation/arterial oxygen blood saturation) and P0.1/SaO2 (mouth occlusion pressure/oxygen arterial blood saturation) remained relatively stable throughout the examined period exhibiting low-amplitude differences from one another with the maximum variation at 12:00 hours.
Siekierka
M
M
Department of Physiology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Tafil-Klawe
M
M
Adamczyk
W
W
Klawe
J J
JJ
Złomańczuk
P
P
D000328:Adult; D000399:Air Pressure; D002940:Circadian Rhythm; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010100:Oxygen / Q000097:blood; D012018:Reflex / Q000502:physiology*; D012129:Respiratory Function Tests / Q000379:methods*; D015656:Respiratory Mechanics / Q000502:physiology*
D010100:Oxygen