title: Infantile pyoderma gangrenosum.
abstract: Pyoderma gangrenosum (PG) is rare in infants. There have been 12 cases of PG in infants (<12 months old) reported in the past 25 years, to our knowledge. Six of these cases have been successfully controlled with systemic steroids, and one case with topical steroids alone. We report a case of an 8-month-old infant whose PG was aggressive and unresponsive to systemic steroids. Adjuvant treatment with cyclosporine was required to achieve healing. We review the previous cases of infantile PG and the therapeutic options in this age group.
authors.affiliation: Regional Centre of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland. maeve_mc_aleer@hotmail.com
authors.forename: Maeve A
authors.initials: MA
authors.lastname: McAleer
authors.forename: Frank C
authors.initials: FC
authors.lastname: Powell
authors.forename: Deirdre
authors.initials: D
authors.lastname: Devaney
authors.forename: Brigid F
authors.initials: BF
authors.lastname: O'Donnell
mesh_terms: D001623:Betamethasone / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D005672:Fusidic Acid / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000188:drug therapy*; D012837:Silver Sulfadiazine / Q000627:therapeutic use
chemical_list: D005672:Fusidic Acid; D016572:Cyclosporine; D001623:Betamethasone; D011239:Prednisolone; D012837:Silver Sulfadiazine