title: Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a rarely reported cause of necrotizing fasciitis. We report an unusually severe case of MRSA necrotizing fasciitis in a previously undiagnosed AIDS patient. Molecular analysis revealed that the strain had the USA300/spa1 genotype, now an abundant cause of community-acquired MRSA infection.
authors.affiliation: Department of Pathology and Laboratory Medicine, The Methodist Hospital, and Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX 77030, USA.
authors.forename: Randall J
authors.initials: RJ
authors.lastname: Olsen
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Burns
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.forename: Barry N
authors.initials: BN
authors.lastname: Kreiswirth
authors.forename: James M
authors.initials: JM
authors.lastname: Musser
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D019115:Fasciitis, Necrotizing / Q000382:microbiology*; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents