title: [Prevention of prosthesis infections].
abstract: Prosthetic infection is a feared complication to surgery with alloplastics and has a high degree of comorbidity. Prophylaxis is concentrated on commonly-accepted hygienic behaviour, optimization of the patient's general health status, peri-operative antibiotics (one dose before surgery and three doses during the first 24 hours postoperatively) and antibiotic loaded cement. Laminary flow reduces the risk of prosthesis infection but there is no clear evidence of any effect to concomitant antibiotic prophylaxis.
authors.affiliation: Arhus Universitetshospital, Arhus Sygehus, Ortopaedkirurgisk Afdeling, Tumor-infektionssektoren, Arhus C. phjor@as.aaa.dk
authors.forename: Peter Holmberg
authors.initials: PH
authors.lastname: Jørgensen
authors.forename: Kirill
authors.initials: K
authors.lastname: Gromov
authors.forename: Kjeld
authors.initials: K
authors.lastname: Søballe
mesh_terms: D000391:Air Microbiology; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D019072:Antibiotic Prophylaxis; D019643:Arthroplasty, Replacement; D001843:Bone Cements; D004780:Environment, Controlled; D006801:Humans; D017053:Infection Control / Q000379:methods; D009873:Operating Rooms; D011300:Preoperative Care / Q000379:methods; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D012307:Risk Factors; D014691:Ventilation
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements