The repair effects of Achyranthes bidentata extract on the crushed common peroneal nerve of rabbits.
In this study the effect of the Achyranthes bidentata root aqueous extract on regeneration of the crushed common peroneal nerve in rabbits by using a combination of electrophysiological assessment and histological aspect were investigated. The examined functional and morphological parameters suggest that A. bidentata extract could accelerate peripheral nerve regeneration in a dose-dependent manner (10-20 microg/kg, i.v.).
Ding
Fei
F
Jiangsu Key Laboratory of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong, JS 226001, PR China. shengdd@public.nt.js.cn
Cheng
Qiong
Q
Gu
Xiaosong
X
D029044:Achyranthes; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D003444:Crush Syndrome / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D004594:Electrophysiology; D007262:Infusions, Intravenous; D009416:Nerve Regeneration / Q000187:drug effects*; D010543:Peroneal Nerve / Q000293:injuries* / Q000503:physiopathology / Q000648:ultrastructure; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D011817:Rabbits
D000700:Analgesics; D010936:Plant Extracts