title: Noninvasive ventilation for acute respiratory failure near the end of life.
abstract: BACKGROUND
  For patients with acute respiratory failure who have declined intubation and resuscitation or have chosen comfort measures only, noninvasive ventilation (NIV) may help them achieve important health or personal goals, or merely prolong the dying process.
  
  
  OBJECTIVE
  To determine clinicians' attitudes to and stated use of NIV for these patients.
  
  
  METHODS
  We developed an instrument to assess the attitudes of intensivists, pulmonologists, and respiratory therapists (RTs) toward the use of NIV for patients with acute respiratory failure near or at the end of life. After assessing its psychometric properties, we mailed the survey to these clinicians at 18 Canadian and two U.S. hospitals. We analyzed factors associated with stated use of NIV for do-not-resuscitate and comfort-measures-only patients.
  
  
  RESULTS
  Overall, 104 of 183 (57%) physicians and 290 of 473 (61%) RTs participated. Two thirds of physicians include NIV during life support discussions with do-not-resuscitate patients at least sometimes, and 87% of RTs stated that NIV should be included in such discussions. For patients choosing comfort measures only, almost half of physicians reported including NIV as an option in their discussions at least sometimes, while fewer than half of RTs stated that these discussions should be conducted. Most (>80%) physicians use NIV and most (>80%) RTs are asked to initiate NIV for do-not-resuscitate patients with chronic obstructive pulmonary disease or cardiogenic pulmonary edema. Fewer clinicians report using NIV for do-not-resuscitate patients with underlying malignancy (59% of physicians, 69% of RTs) or for patients choosing comfort measures only (40% of physicians, 51% of RTs; p < .001).
  
  
  CONCLUSIONS
  For patients with do-not-resuscitate orders, many physicians use NIV, and many RTs are asked to initiate NIV, most often to treat chronic obstructive pulmonary disease and cardiogenic pulmonary edema. Further study is needed on the goals of NIV near the end of life, whether these goals are understood by all stakeholders, and how well they are achieved in practice.
authors.affiliation: Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. taz.sinuff@sunnybrook.ca
authors.forename: Tasnim
authors.initials: T
authors.lastname: Sinuff
authors.forename: Deborah J
authors.initials: DJ
authors.lastname: Cook
authors.forename: Sean P
authors.initials: SP
authors.lastname: Keenan
authors.forename: Karen E A
authors.initials: KE
authors.lastname: Burns
authors.forename: Neill K J
authors.initials: NK
authors.lastname: Adhikari
authors.forename: Graeme M
authors.initials: GM
authors.lastname: Rocker
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Mehta
authors.forename: Robert
authors.initials: R
authors.lastname: Kacmarek
authors.forename: Kevin
authors.initials: K
authors.lastname: Eva
authors.forename: Nicholas S
authors.initials: NS
authors.lastname: Hill
mesh_terms: D001291:Attitude of Health Personnel; D006801:Humans; D010818:Practice Patterns, Physicians'; D012121:Respiration, Artificial / Q000706:statistics & numerical data*; D012128:Respiratory Distress Syndrome / Q000628:therapy*; D013727:Terminal Care