title: Brain magnetic resonance imaging findings in acute relapses of neuromyelitis optica spectrum disorders.
abstract: We studied cranial magnetic resonance imaging (MRI) lesions in three women with acute attacks of recurrent longitudinally extensive transverse myelitis (r-LETM), recurrent-optic neuritis (r-ON) and r-LETM-CNS. Neuromyelitis Optica -immunoglobulin (IgG) antibody was positive in all cases. Brain MRI (1.5 Tesla) was performed according to protocol from consortium MS centre. We described the cranial lesions in brain MRI of acute relapses. These lesions were different from MS, most had an asymptomatic course which disappeared with time, protocol from consortium of MS centre criteria for brain MRI and seropositivity of NMO-IgG are useful tools for differentiate acute lesions of NMO/MS.
authors.affiliation: International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba. cabrera.gomez@infomed.sld.cu
authors.forename: Ja
authors.initials: J
authors.lastname: Cabrera-Gómez
authors.forename: A
authors.initials: A
authors.lastname: Saiz-Hinarejos
authors.forename: F
authors.initials: F
authors.lastname: Graus
authors.forename: A
authors.initials: A
authors.lastname: González-Quevedo
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez-Rojas
authors.forename: L
authors.initials: L
authors.lastname: Quevedo-Sotolongo
authors.forename: Y
authors.initials: Y
authors.lastname: Real-González
authors.forename: D
authors.initials: D
authors.lastname: Grass-Fernández
authors.forename: M
authors.initials: M
authors.lastname: Cristófol-Corominas
authors.forename: Ml
authors.initials: M
authors.lastname: Rodríguez-Cordero
authors.forename: Ma
authors.initials: M
authors.lastname: Robinson-Agramonte
authors.forename: E
authors.initials: E
authors.lastname: Infante-Velázquez
authors.forename: A
authors.initials: A
authors.lastname: Cabrera-Núñez
authors.forename: C
authors.initials: C
authors.lastname: Ugarte-Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Jordán-González
authors.forename: Je
authors.initials: J
authors.lastname: González de la Nuez
authors.forename: J
authors.initials: J
authors.lastname: García-Lahera
authors.forename: R
authors.initials: R
authors.lastname: Tellez
authors.forename: M
authors.initials: M
authors.lastname: Baez-Martín
authors.forename: K
authors.initials: K
authors.lastname: Romero-García
mesh_terms: D000208:Acute Disease; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008279:Magnetic Resonance Imaging; D009471:Neuromyelitis Optica / Q000276:immunology / Q000473:pathology*; D012008:Recurrence
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G