title: Increased rates of obesity in first-presentation adults with mood disorders over the course of four-year follow-up.
abstract: BACKGROUND
  Patients with mood disorders have higher rates of obesity than the general population. With respect to this, little is known regarding how patient look like prior to treatment or the rates of change.
  
  
  OBJECTIVE
  To identify changes in the rates of obesity in never-treated patients with mood disorder over 4 years of follow-up.
  
  
  METHODS
  Sixty-six never-treated patients with mood disorders were evaluated via clinical interview, symptom assessment and body mass index (BMI). Patients were followed 4 years. Population attributable risk (PAR%) was calculated.
  
  
  RESULTS
  Patients in underweight and normal weight groups fell by nearly 29%, with a corresponding increase in patients entering overweight and obese groups. Rates of PAR% increased to 16.0, a significant 5-point increase over baseline.
  
  
  CONCLUSIONS
  This study had a small sample size and the population was ethnically homogenous. BMI was used as a maker of weight and not waist circumference.
  
  
  CONCLUSIONS
  Over 4 years there was a significant increase in BMI and the risk conferred by obesity. Shift from normal weight to overweight and obese is a significant risk for patients with a mood disorder and clinical programs should consider interventions that might ameliorate risk of this shift early in the course of the illness.
authors.affiliation: McMaster University, Hamilton, ON, Canada.
authors.forename: Valerie
authors.initials: V
authors.lastname: Taylor
authors.forename: Kathryn
authors.initials: K
authors.lastname: Macdonald
authors.forename: Margaret C
authors.initials: MC
authors.lastname: McKinnon
authors.forename: Russell T
authors.initials: RT
authors.lastname: Joffe
authors.forename: Glenda M
authors.initials: GM
authors.lastname: MacQueen
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D009765:Obesity / Q000453:epidemiology* / Q000401:mortality; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires