Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.
A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.
Brennan
Mary R
MR
Gustaf H. Carlson School of Chemsitry and Biochemistry, Clark University , Worcester, Massachusetts 01610, USA.
Costello
Catherine E
CE
Maleknia
Simin D
SD
Pettit
George R
GR
Erickson
Karen L
KL
D000818:Animals; D015394:Molecular Structure; D010219:Papua New Guinea; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification*; D011161:Porifera / Q000737:chemistry*; D011392:Proline / Q000737:chemistry
D010456:Peptides, Cyclic; C529038:stylopeptide 2; D011392:Proline