title: A novel nano-micro structured octacalcium phosphate/protein composite coating on titanium by using an electrochemically induced deposition.
abstract: In this study, a novel nano-micro structured octacalcium phosphate/protein (OCP/protein) composite coating has been successfully constructed on titanium substrate by using an electrochemically induced deposition technique. The structure and composition of the composite coating were investigated by XRD, XPS, SEM and FTIR. It is shown that the composite coating consists of OCP and protein with a highly ordered and hierarchically porous structure in nano-micro scale, similar to the naturalbone structure. The nanoindentation experiment proves a good mechanical property for the OCP/protein composite coating on titanium substrate. In the osteoblast cell culture in vitro, the cell adhesion for the OCP/protein composite coating is observed to be greatly improved.
authors.affiliation: State Key Laboratory for Physical Chemistry of Solid Surfaces, Department of Chemistry, Xiamen University, Xiamen, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Chang-Jian
authors.initials: CJ
authors.lastname: Lin
authors.forename: Ren
authors.initials: R
authors.lastname: Hu
authors.forename: Fan
authors.initials: F
authors.lastname: Zhang
authors.forename: Li-Wen
authors.initials: LW
authors.lastname: Lin
mesh_terms: D000818:Animals; D018786:Bone Substitutes / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D002478:Cells, Cultured; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis*; D004563:Electrochemistry / Q000379:methods; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures / Q000737:chemistry; D010006:Osteoblasts; D016062:Porosity; D051381:Rats; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; C022045:octacalcium phosphate; D014025:Titanium