title: Temporal patterns of recovery across eating disorder subtypes.
abstract: OBJECTIVE
  To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN).
  
  
  METHODS
  Using Kaplan-Meier methods and Cox proportional hazards models, comparisons were conducted that were conditional on duration of eating disorder from onset and included a conservative recovery criterion of 3 asymptomatic years. Data collection was retrospective and from two of the international Price Foundation genetic studies on 901 individuals with eating disorders.
  
  
  RESULTS
  Using Kaplan-Meier methods, 11% of those with index AN and 10% of those with index BN met recovery criteria at 10 years. At 15 years, 16% of those with index AN and 25% of those with index BN met recovery criteria. In a Cox proportional hazards model the index BN group had three times the rate of recovery at 10-14 years (p=0.01) than the index AN group.
  
  
  CONCLUSIONS
  Initially the probability of recovery was greater for those with index AN, but as the duration of the eating disorder lengthened those with BN had higher probabilities of recovery. Replication of these results with prospective data using similarly stringent recovery criteria and methods is required to confirm trends.
authors.affiliation: Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599-7160, USA.
authors.forename: Ann
authors.initials: A
authors.lastname: Von Holle
authors.forename: Andréa Poyastro
authors.initials: AP
authors.lastname: Pinheiro
authors.forename: Laura M
authors.initials: LM
authors.lastname: Thornton
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Klump
authors.forename: Wade H
authors.initials: WH
authors.lastname: Berrettini
authors.forename: Harry
authors.initials: H
authors.lastname: Brandt
authors.forename: Steven
authors.initials: S
authors.lastname: Crawford
authors.forename: Scott
authors.initials: S
authors.lastname: Crow
authors.forename: Manfred M
authors.initials: MM
authors.lastname: Fichter
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Halmi
authors.forename: Craig
authors.initials: C
authors.lastname: Johnson
authors.forename: Allan S
authors.initials: AS
authors.lastname: Kaplan
authors.forename: Pamela
authors.initials: P
authors.lastname: Keel
authors.forename: Maria
authors.initials: M
authors.lastname: La Via
authors.forename: James
authors.initials: J
authors.lastname: Mitchell
authors.forename: Michael
authors.initials: M
authors.lastname: Strober
authors.forename: D Blake
authors.initials: DB
authors.lastname: Woodside
authors.forename: Walter H
authors.initials: WH
authors.lastname: Kaye
authors.forename: Cynthia M
authors.initials: CM
authors.lastname: Bulik
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis; D052018:Bulimia Nervosa / Q000175:diagnosis; D001068:Feeding and Eating Disorders / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors