title: Application of glycosyl thioimidates in solid-phase oligosaccharide synthesis.
abstract: Two stable classes of thioimidoyl derivatives, S-benzoxazolyl (SBox) and S-thiazolinyl (STaz) glycosides, were investigated as glycosyl donors for solid-phase oligosaccharide synthesis. It was demonstrated that these derivatives are suitable for both glycosyl acceptor-bound and glycosyl donor-bound strategies, commonly employed in resin-supported oligosaccharide synthesis.
authors.affiliation: Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Parlato
authors.forename: Medha N
authors.initials: MN
authors.lastname: Kamat
authors.forename: Haisheng
authors.initials: H
authors.lastname: Wang
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Stine
authors.forename: Alexei V
authors.initials: AV
authors.lastname: Demchenko
mesh_terms: D007094:Imides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009844:Oligosaccharides / Q000138:chemical synthesis*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D007094:Imides; D009844:Oligosaccharides; D013438:Sulfhydryl Compounds