title: [Genetic variation in RXRG gene and its relationship with twinning trait in cattle].
abstract: Retinoic X receptor-gamma (RXRG) gene was studied as a candidate gene for the twinning trait of bovine. A new SNP A1941G was detected by sequencing at 3'UTR. Different genotypes were determined in Luxi monotocous cows, Luxi twinning cows, Chinese Simmental cows, Angus cows and Simmental x Mongolia cows by restriction fragment length polymorphism (RFLP). The value of polymorphism information content indicated that this was a moderate polymorphism in Luxi monotocous cows and Luxi twinning cows. The chi(2) test indicated that the polymorphic locus in Luxi twinning cows did not fit Hardy-Weinberg equilibrium (Plt;0.05). The chi(2) test of associational analysis between genotypic distribution and twinning or monotocous trait in Luxi cows showed that the difference was very significant (Plt;0.01).
authors.affiliation: College of Animal Science-technology, Northwest A &F University, Yangling 712100, China. huangmeng82@yahoo.com.cn
authors.forename: Meng
authors.initials: M
authors.lastname: Huang
authors.forename: Shang-Zhong
authors.initials: SZ
authors.lastname: Xu
authors.forename: Lin-Sen
authors.initials: LS
authors.lastname: Zan
authors.forename: Lu-Pei
authors.initials: LP
authors.lastname: Zhang
authors.forename: Xue
authors.initials: X
authors.lastname: Gao
authors.forename: Jin-Bao
authors.initials: JB
authors.lastname: Chen
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle / Q000235:genetics* / Q000502:physiology*; D004247:DNA / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D006579:Heterozygote; D016013:Likelihood Functions; D009154:Mutation; D020641:Polymorphism, Single Nucleotide; D047491:Retinoid X Receptor gamma / Q000235:genetics* / Q000378:metabolism; D014427:Twins / Q000235:genetics
chemical_list: D047491:Retinoid X Receptor gamma; D004247:DNA