Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals.
We have evaluated four current Food and Drug Administration-cleared rapid tests for human immunodeficiency virus (HIV)-specific antibodies with a panel of specimens from recently infected individuals. Recent infection was detected by RNA-based screening coupled with enzyme immunoassay-based testing. We found that the sensitivities of the various rapid tests vary greatly with regard to their ability to detect HIV-specific antibodies in recently infected individuals.
Louie
Brian
B
San Francisco Department of Public Health, 101 Grove St., Room 412, San Francisco, CA 94102, USA. brian.louie@sfdph.org
Wong
Ernest
E
Klausner
Jeffrey D
JD
Liska
Sally
S
Hecht
Frederick
F
Dowling
Terri
T
Obeso
Martha
M
Phillips
Susan S
SS
Pandori
Mark W
MW
D015492:AIDS Serodiagnosis / Q000379:methods*; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D007118:Immunoassay; D007124:Immunoenzyme Techniques; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013997:Time Factors; D014481:United States; D014486:United States Food and Drug Administration
D015483:HIV Antibodies; D011933:Reagent Kits, Diagnostic