Re: Apnea in a child after oral codeine: a genetic variant - an ultra-rapid metabolizer [corrected].
de Wildt
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The Hospital for Sick Children, Department of Pediatrics, Division of Clinical Pharmacology and Toxicology, Toronto, ON, Canada, and Erasmus MC Sophia Children's Hospital, Departments of Pediatric Surgery and Pediatrics, Rotterdam, The Netherlands.
Koren
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D000701:Analgesics, Opioid / Q000009:adverse effects / Q000378:metabolism*; D002648:Child; D003061:Codeine / Q000009:adverse effects / Q000378:metabolism*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D006801:Humans; D009020:Morphine / Q000378:metabolism; D010597:Pharmacogenetics; D010641:Phenotype
D000701:Analgesics, Opioid; D009020:Morphine; D019389:Cytochrome P-450 CYP2D6; D003061:Codeine