Improved outcome with multimodality therapy in primary cardiac angiosarcoma.
BACKGROUND
A 37-year-old man presented with a history of hemoptysis and associated fever, chills, night sweats, and weight loss. The patient had no other pertinent past medical history.


METHODS
Physical examination, CT scan, transesophageal echocardiogram, electrocardiogram, MRI scan, and immunohistochemical staining of tumor biopsy.


METHODS
Primary cardiac angiosarcoma of the right atrium with systemic metastases to the pericardium, superior vena cava, and lungs.


RESULTS
Neoadjuvant and adjuvant chemotherapy with doxorubicin and complete surgical resection of the tumor with reconstruction of the right atrium using bovine pericardium.
Pigott
Courtney
C
Rush Medical College, Rush University Medical Center, Chicago, IL 60612, USA.
Welker
Michael
M
Khosla
Pam
P
Higgins
Robert S D
RS
D000328:Adult; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D002417:Cattle; D017024:Chemotherapy, Adjuvant; D004317:Doxorubicin / Q000627:therapeutic use*; D006338:Heart Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D009362:Neoplasm Metastasis; D019651:Plastic Surgery Procedures
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin