title: Imaging diagnosis of monostotic fibrous dysplasia in thoracic and lumbar spine vertebrae.
abstract: The X-ray radiograph, CT scan and MRI appearance of 5 patients with pathologically proven fibrous dysplasia in thoracic and lumbar spine vertebrae were retrospectively analyzed. Plain radiographs, CT scans and MR images showed the presentation of eccentric lesion with intact cortex bone and marginal sclerosis in vertebral bodies without involvement of vertebral appendix and extraosseous soft tissue. The lesion masses were round (one being oval-shaped) and radiolucent in plain radiographs and CT scans. Homogeneous long signal was observed on T1 weighted image and strongly enhanced when gadolinium was administered. On T2 weighted MRI, short signal was found in the anterior part of the mass, long signal in the posterior part, and short and slight long signal in the middle part, without partitioning and laminating change. There was a good correlation between radiological features and surgical findings. These findings may be useful to diagnose fibrous dysplasia in spine.
authors.affiliation: Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. yangcaihong@yahoo.com
authors.forename: Caihong
authors.initials: C
authors.lastname: Yang
authors.forename: Bo
authors.initials: B
authors.lastname: Zhu
authors.forename: Anmin
authors.initials: A
authors.lastname: Chen
mesh_terms: D000328:Adult; D005260:Female; D005358:Fibrous Dysplasia, Monostotic / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed; D055815:Young Adult