Effect of tetrapeptide pancragene on functional morphology of the pancreas in rats with experimental diabetes mellitus.
The regulatory effect of tetrapeptide pancragene on the morphology and function of pancreatic tissues was shown in rats with diabetes mellitus, which suggests good prospects of this drug.
Kvetnoi
I M
IM
St. Petersburg Institute of Bioregulation and Gerontology, NorthWestern Branch of the Russian Academy of Medical Sciences.
Ryzhak
A P
AP
Kostyuchek
I N
IN
Tafeev
Yu A
YA
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D005934:Glucagon / Q000096:biosynthesis; D007328:Insulin / Q000096:biosynthesis; D009842:Oligopeptides / Q000494:pharmacology*; D010179:Pancreas / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism; D051381:Rats; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
D007328:Insulin; D009842:Oligopeptides; D018809:Proliferating Cell Nuclear Antigen; D016159:Tumor Suppressor Protein p53; C511188:lysyl-glutamyl-aspartyl-tryptophan; D005934:Glucagon