title: [Multimodal medical image registration using cubic spline interpolation method].
abstract: Based on the characteristic of the PET-CT multimodal image series, a novel image registration and fusion method is proposed, in which the cubic spline interpolation method is applied to realize the interpolation of PET-CT image series, then registration is carried out by using mutual information algorithm and finally the improved principal component analysis method is used for the fusion of PET-CT multimodal images to enhance the visual effect of PET image, thus satisfied registration and fusion results are obtained. The cubic spline interpolation method is used for reconstruction to restore the missed information between image slices, which can compensate for the shortage of previous registration methods, improve the accuracy of the registration, and make the fused multimodal images more similar to the real image. Finally, the cubic spline interpolation method has been successfully applied in developing 3D-CRT (3D Conformal Radiation Therapy) system.
authors.affiliation: College of Automation Science and Engineering, South China University of Technology, Guangzhou 510640, China.
authors.forename: Yuanlie
authors.initials: Y
authors.lastname: He
authors.forename: Lianfang
authors.initials: L
authors.lastname: Tian
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.forename: Lifei
authors.initials: L
authors.lastname: Wang
authors.forename: Guangchun
authors.initials: G
authors.lastname: Ye
authors.forename: Zongyuan
authors.initials: Z
authors.lastname: Mao
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000295:instrumentation / Q000379:methods; D010363:Pattern Recognition, Automated / Q000379:methods*; D049268:Positron-Emission Tomography / Q000295:instrumentation / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*