title: Involvement of the serotoninergic system in the mechanism of action of ultralow dose antibodies to S-100 protein.
abstract: The involvement of the serotoninergic system in the realization of anxiolytic and antidepressant activities of antibodies to S-100 protein in ultralow doses is proven. Administration of ultralow-dose antibodies to S-100 protein in combination with serotoninergic agents (ketanserin and 5-hydroxytryptophan) reduced the anxiolytic and antidepressant effects of antibodies.
authors.affiliation: Materia Medica Holding, Moscow, Russia. heifezia@materiamedica.ru
authors.forename: I A
authors.initials: IA
authors.lastname: Kheifets
authors.forename: Yu L
authors.initials: YL
authors.lastname: Dugina
authors.forename: T A
authors.initials: TA
authors.lastname: Voronina
authors.forename: G M
authors.initials: GM
authors.lastname: Molodavkin
authors.forename: A V
authors.initials: AV
authors.lastname: Martyushev-Poklad
authors.forename: S A
authors.initials: SA
authors.lastname: Sergeeva
authors.forename: O I
authors.initials: OI
authors.lastname: Epstein
mesh_terms: D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D007650:Ketanserin / Q000494:pharmacology; D008297:Male; D051381:Rats; D009418:S100 Proteins / Q000276:immunology*; D012701:Serotonin / Q000502:physiology*; D012702:Serotonin Antagonists / Q000494:pharmacology
chemical_list: D009418:S100 Proteins; D012702:Serotonin Antagonists; D012701:Serotonin; D007650:Ketanserin