beta(1)-adrenoceptor polymorphisms: deviation of clinical outcome with use of beta-blockers in ventricular dysfunction.
While the debate continues regarding the role of polymorphisms of beta(1)-adrenoceptors on the clinical outcomes and beneficial effects of beta-blockers in patients with heart failure, we need to step back and examine the evidence in the peer-reviewed literature more closely.
Tabrizchi
Reza
R
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D006801:Humans; D011110:Polymorphism, Genetic; D018342:Receptors, Adrenergic, beta-1 / Q000235:genetics*; D016896:Treatment Outcome; D018754:Ventricular Dysfunction / Q000188:drug therapy* / Q000235:genetics*
D000319:Adrenergic beta-Antagonists; D018342:Receptors, Adrenergic, beta-1