title: Pneumocephalus as a complication of multidrug-resistant Klebsiella pneumoniae meningitis.
abstract: Pneumocephalus implies air inside the cranial vault, which usually results from cranio-facial trauma. Occasionally, meningitis caused by gas-forming organisms can result in pneumocephalus. Klebsiella pneumoniae meningitis can, on rare occasions, cause pneumocephalus as a complication. The drug of choice for K. pneumoniae meningitis is a third-generation cephalosporin, and resistance to these drugs is unusual. We report a case of multidrug-resistant K. pneumoniae meningitis resulting from chronic suppurative otitis media, which was later complicated by pneumocephalus. The patient was successfully managed with meropenam and amikacin, the only antibiotics to which these bacilli showed no resistance.
authors.affiliation: Department of Medicine, Kottayam Medical College, South India.
authors.forename: P
authors.initials: P
authors.lastname: Sreejith
authors.forename: V
authors.initials: V
authors.lastname: Vishad
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Pappachan
authors.forename: D C
authors.initials: DC
authors.lastname: Laly
authors.forename: R
authors.initials: R
authors.lastname: Jayaprakash
authors.forename: V T
authors.initials: VT
authors.lastname: Ranjith
mesh_terms: D000328:Adult; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications* / Q000188:drug therapy; D007711:Klebsiella pneumoniae / Q000302:isolation & purification*; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications* / Q000188:drug therapy; D011007:Pneumocephalus / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome