title: Modeling photon propagation in biological tissues using a generalized Delta-Eddington phase function.
abstract: Photon propagation in biological tissue is commonly described by the radiative transfer equation, while the phase function in the equation represents the scattering characteristics of the medium and has significant influence on the precision of solution and the efficiency of computation. In this work, we present a generalized Delta-Eddington phase function to simplify the radiative transfer equation to an integral equation with respect to photon fluence rate. Comparing to the popular diffusion approximation model, the solution of the integral equation is highly accurate to model photon propagation in the biological tissue over a broad range of optical parameters. This methodology is validated by Monte Carlo simulation.
authors.affiliation: Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Drive, Suite 2000, Blacksburg, Virginia 24061, USA.
authors.forename: W
authors.initials: W
authors.lastname: Cong
authors.forename: H
authors.initials: H
authors.lastname: Shen
authors.forename: A
authors.initials: A
authors.lastname: Cong
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: G
authors.initials: G
authors.lastname: Wang
mesh_terms: D000818:Animals; D003198:Computer Simulation; D003238:Connective Tissue / Q000502:physiology*; D006801:Humans; D008027:Light; D008954:Models, Biological; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D017785:Photons; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012031:Refractometry / Q000379:methods*