The presence of erythropoietin receptor in parathyroid cells.
BACKGROUND
Effects of erythropoietin on parathyroid cell function has not been studied before.


OBJECTIVE
We aimed to demonstrate whether erythropoietin receptor present in parathyroid cells.


METHODS
The specimens of normal parathyroid gland, parathyroid adenoma and hyperplasia were retrieved from our pathology archives. The sections were stained immunohistochemically. Quantitative gene expression study was performed for erythropoietin and erythropoietin receptor.


RESULTS
Erythropoietin receptors were detected by immunohistochemical staining and by its gene expression. Its density was higher in normal parathyroid, followed by parathyroid adenoma and hyperplasia.


CONCLUSIONS
Erythropoietin receptor is present in normal parathyroid, parathyroid adenoma, and hyperplasia.
Oztürk
M
M
Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey. drmustafa@hotmail.com
Ustek
D
D
Akbas
F
F
Kösem
M
M
Abaci
N
N
Alagöl
F
F
Oztürk
G
G
Kotan
C
C
D000236:Adenoma / Q000378:metabolism* / Q000473:pathology; D004921:Erythropoietin / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D006965:Hyperplasia / Q000378:metabolism / Q000473:pathology; D010280:Parathyroid Glands / Q000378:metabolism* / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000378:metabolism* / Q000473:pathology; D017467:Receptors, Erythropoietin / Q000235:genetics / Q000378:metabolism*
D017467:Receptors, Erythropoietin; D004921:Erythropoietin