title: Calcium intake and metabolic bone disease after eight years of Roux-en-Y gastric bypass.
abstract: BACKGROUND
  Roux-en-Y gastric bypass (RYGBP) has been found to be the most efficient way to lose weight and maintain the weight loss in morbid obesity. However, with the formation of a new stomach and the modification of intestinal anatomy, there are significant changes on physiological properties of these organs that lead to nutrient deficiency, including calcium. The objectives of this study were to evaluate calcium intake, bone metabolism, and prevalence of metabolic bone disease in women subjected to RYGBP after 8 years.
  
  
  METHODS
  Food frequency questionnaire and 3-day dietary recall, laboratory tests of bone metabolism and bone mineral density were accessed.
  
  
  RESULTS
  Calcium intake was below the recommendation in all women. Serum PTH and alkaline phosphatase were elevated, whereas vitamin D and urinary calcium were significantly lower. Also, a higher prevalence of metabolic bone disease than the one expected for the normal population at the same age was noted.
  
  
  CONCLUSIONS
  These data suggest that metabolic bone disease could be a complication of this type of surgery.
authors.affiliation: Obesity Division, Department of Endocrinology, University of São Paulo School of Medicine, São Paulo, Brazil. camila.duran@ig.com.br
authors.forename: Camila
authors.initials: C
authors.lastname: Duran de Campos
authors.forename: Lorença
authors.initials: L
authors.lastname: Dalcanale
authors.forename: Denis
authors.initials: D
authors.lastname: Pajecki
authors.forename: Arthur B
authors.initials: AB
authors.lastname: Garrido
authors.forename: Alfredo
authors.initials: A
authors.lastname: Halpern
mesh_terms: D000328:Adult; D000368:Aged; D001851:Bone Diseases, Metabolic / Q000453:epidemiology*; D016723:Bone Remodeling / Q000502:physiology*; D002136:Calcium, Dietary; D004032:Diet; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D006801:Humans; D008875:Middle Aged; D009752:Nutritional Status; D009767:Obesity, Morbid / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D010349:Patient Compliance; D013997:Time Factors
chemical_list: D002136:Calcium, Dietary