Total synthesis of (+/-)-5,14-bis-epi-spirovibsanin A.
The total synthesis of (+/-)-5,14-bis-epi-spirovibsanin A was achieved in 18 steps. Physical data obtained from (+/-)-5,14-bis-epi-spirovibsanin A lends strong support to the proposed connectivity and relative stereochemistry of spirovibsanin A.
Gallen
Michael J
MJ
School of Molecular and Microbial Sciences, University of Queensland, Brisbane 4072, Queensland, Australia.
Williams
Craig M
CM
D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D027925:Viburnum / Q000737:chemistry
C527608:5,14-bis-epi-spirovibsanin A; D004224:Diterpenes; D013141:Spiro Compounds; C527607:spirovibsanin A