Mycosis fungoides mimicking erysipelas.
Mycosis fungoides may rarely simulate facial erysipelas. In a patient with that clinical presentation, a biopsy specimen revealed a diffuse dermal infiltrate with numerous neutrophils that also mimicked erysipelas histopathologically. The diagnosis of mycosis fungoides was made on the basis of atypical lymphocytes with focal epidermo- and folliculotropism. It was confirmed by typical findings of mycosis fungoides in a second biopsy from a clinically inconspicuous patch. An identical T-cell receptor gamma-gene rearrangement was detected in lymphocytes of both biopsy specimens.
Weyers
Wolfgang
W
Center for Dermatopathology Freiburg, Freiburg, Germany. ww@zdpf.de
Diaz-Cascajo
Carlos
C
Preinfalk
Peter
P
Löffler
Harald
H
D001706:Biopsy; D003937:Diagnosis, Differential; D004886:Erysipelas / Q000175:diagnosis*; D005153:Facial Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D005260:Female; D015334:Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D006377:T-Lymphocytes, Helper-Inducer / Q000473:pathology