title: Blunt trauma: feasibility and clinical utility of pelvic CT angiography performed with 64-detector row CT.
abstract: OBJECTIVE
  To retrospectively evaluate the integration of pelvic computed tomographic (CT) angiography into the thoracoabdominal CT examination of blunt trauma by using 64-detector row CT to differentiate active arterial from active venous hemorrhage.
  
  
  METHODS
  This study was institutional review board approved and HIPAA compliant; the requirement for informed patient consent was waived. Fifty-three patients (30 male, 23 female; mean age, 42 years) with multiple blunt trauma underwent pelvic CT angiography with 64-detector row CT at admission. Arterial phase and portal venous phase pelvic CT angiograms were evaluated for evidence of vascular injury. In patients with active extravasation, the size of the hemorrhaging area was measured on arterial, portal venous, and delayed phase images. The Fisher exact test was used to correlate presence of vascular injury with subsequent clinical management. The Wilcoxon rank sum test was used to test the association between size of active hemorrhage during the vascular enhancement phases and subsequent clinical outcome. Finally, the Fisher exact test was used to correlate presence of vascular injury with severity of osseous injury.
  
  
  RESULTS
  At pelvic CT angiography, 21 of the 53 patients had evidence of vascular injury: 10 isolated active arterial extravasations, three isolated arterial occlusions, three cases of both arterial extravasation and occlusion, two cases of arterial and venous extravasations, and three isolated venous extravasations. Eleven of the 21 patients also underwent conventional angiography, with subsequent embolization performed in seven of these 11 patients. The remaining 10 patients were successfully treated conservatively. When the foci of active arterial extravasation were compared on arterial, portal venous, and delayed phase images, the mean areas of hemorrhage across all three phases were larger in patients who required conventional angiography than in those successfully treated with conservative management.
  
  
  CONCLUSIONS
  With use of 64-detector row scanning, pelvic CT angiography was successfully integrated into the authors' CT protocols and enabled differentiation between active arterial and active venous hemorrhage, which may influence clinical management.
authors.affiliation: Department of Radiology, Boston University Medical Center, 88 E Newton St, 2nd Floor, Boston, MA 02215, USA. Stephan.anderson@bmc.org
authors.forename: Stephan W
authors.initials: SW
authors.lastname: Anderson
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Soto
authors.forename: Brian C
authors.initials: BC
authors.lastname: Lucey
authors.forename: Peter A
authors.initials: PA
authors.lastname: Burke
authors.forename: Erwin F
authors.initials: EF
authors.lastname: Hirsch
authors.forename: James T
authors.initials: JT
authors.lastname: Rhea
mesh_terms: D000328:Adult; D000792:Angiography / Q000379:methods*; D001808:Blood Vessels / Q000293:injuries*; D005240:Feasibility Studies; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D010388:Pelvis / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014949:Wounds, Nonpenetrating / Q000000981:diagnostic imaging*