title: A homemade high-resolution orthogonal-injection time-of-flight mass spectrometer with a heated capillary inlet.
abstract: We describe a homemade high-resolution orthogonal-injection time-of-flight (O-TOF) mass spectrometer combing a heated capillary inlet. The O-TOF uses a heated capillary tube combined with a radio-frequency only quadrupole (rf-only quadrupole) as an interface to help the ion transmission from the atmospheric pressure to the low-pressure regions. The principle, configuration of the O-TOF, and the performance of the instrument are introduced in this paper. With electrospray ion source, the performances of the mass resolution, the sensitivity, the mass range, and the mass accuracy are described. We also include our results obtained by coupling atmospheric pressure matrix-assisted laser deporption ionization with this instrument.
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, People's Republic of China.
authors.forename: Changjuan
authors.initials: C
authors.lastname: Guo
authors.forename: Zhengxu
authors.initials: Z
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.forename: Huiqing
authors.initials: H
authors.lastname: Nian
authors.forename: Huayong
authors.initials: H
authors.lastname: Chen
authors.forename: Junguo
authors.initials: J
authors.lastname: Dong
authors.forename: Guoying
authors.initials: G
authors.lastname: Shen
authors.forename: Jiamo
authors.initials: J
authors.lastname: Fu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhou
mesh_terms: D002197:Capillary Action; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006361:Heating / Q000295:instrumentation*; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation* / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000295:instrumentation*