[Dyslipidemia and abdominal obesity: mechanisms and characteristics (Part I)].
The dyslipidemia classically associated with abdominal obesity is characterised by a metabolic atherogenic triad including an elevation of triglycerides, a low HDL-cholesterol and an excess of small dense LDL fractions. All of these lipid anomalies contribute to an increased cardio-metabolic risk, and are engendered by an excess of visceral adipose tissue. This excess adipose tissue seems to be the direct origin of the dyslipidemia associated with abdominal obesity, causing more free fatty acids to flow into the liver and contributing to insulin resistance.
Farnier
M
M
Point Médical, dijon. michelfarnier@nerim.net
D002318:Cardiovascular Diseases / Q000503:physiopathology; D050171:Dyslipidemias / Q000503:physiopathology*; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D009765:Obesity / Q000503:physiopathology*; D012307:Risk Factors