Review of methodological developments in laser Doppler flowmetry.
Laser Doppler flowmetry is a non-invasive method of measuring microcirculatory blood flow in tissue. In this review the technique is discussed in detail. The theoretical and experimental developments to improve the technique are reviewed. The limitations of the method are elaborated upon, and the research done so far to overcome these limitations is critically assessed.
Rajan
Vinayakrishnan
V
Institute of Biomedical Technology, Biophysical Engineering Group, University of Twente, P.O. Box 217, 7500AE, Enschede, The Netherlands. v.rajan@tnw.utwente.nl
Varghese
Babu
B
van Leeuwen
Ton G
TG
Steenbergen
Wiendelt
W
D001783:Blood Flow Velocity / Q000502:physiology*; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation / Q000379:methods*; D054023:Lasers, Semiconductor; D008833:Microcirculation / Q000502:physiology*; D012542:Scattering, Radiation