A new eudesmane sesquiterpene lactone from Curcuma wenyujin.
The aim of the study was to investigate the sesquiterpene constituents from the rhizomes of Curcuma wenyujin Y. H. Chen et C. Ling. The isolation and purification of the constituents from the 50% EtOH extracts of the rhizomes were performed with repeated column chromatography over sillica gel and macroporous resin. Eight sesquiterpenes were obtained and identified as wenyujinlactone A (1), neolitamone A (2), zedoarondiol (3), isozedoarondiol (4), aerugidiol (5), curcumol (6), curdione (7) and (1R, 10R)-epoxy-(-)-1, 10-dihydrocurdine (8) by means of spectral analysis. Among them, compound 1 was found to be a new eudesmane sesquiterpene lactone, whilst compounds 2-5 were obtained from this plant for the first time.
Wang
Shi-sheng
SS
State Key Laboratory of Fine Chemical Engineering, Dalian University of Technology, Dalian 116012, China. wangssg@sina.com
Zhang
Jin-mei
JM
Guo
Xiu-han
XH
Song
Qi-ling
QL
Zhao
Wei-jie
WJ
D030024:Curcuma / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*
D045787:Sesquiterpenes, Eudesmane; C542806:wenyujinlactone A