title: The STAR*D study: treating depression in the real world.
abstract: The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study evaluated feasible treatment strategies to improve clinical outcomes for real-world patients with treatment-resistant depression. Although the study found no clear-cut "winner", it does provide guidance on how to start therapy and how to proceed if initial treatment fails.
authors.affiliation: Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599, USA. bgaynes@med.unc.edu
authors.forename: Bradley N
authors.initials: BN
authors.lastname: Gaynes
authors.forename: A John
authors.initials: AJ
authors.lastname: Rush
authors.forename: Madhukar H
authors.initials: MH
authors.lastname: Trivedi
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Wisniewski
authors.forename: Donald
authors.initials: D
authors.lastname: Spencer
authors.forename: Maurizio
authors.initials: M
authors.lastname: Fava
mesh_terms: D000465:Algorithms; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015283:Citalopram / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003863:Depression / Q000188:drug therapy* / Q000628:therapy; D018450:Disease Progression; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D015283:Citalopram