Synthesis of an original oxygenated taxuspine X analogue: a versatile "non-natural" natural product with remarkable P-gp modulating activity.
Avramova
Stanislava I
SI
Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Alcide de Gasperi 2, 53100 Siena, Italy.
Galletti
Elena
E
Renzulli
Michela L
ML
Giorgi
Gianluca
G
Sgaragli
Gianpietro
G
Alderighi
Daniela
D
Ghiron
Chiara
C
Corelli
Federico
F
Radi
Marco
M
Botta
Maurizio
M
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors*; D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018432:Drug Resistance, Multiple / Q000187:drug effects; D006801:Humans; D043823:Taxoids / Q000138:chemical synthesis* / Q000737:chemistry
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000970:Antineoplastic Agents; D043823:Taxoids; D000251:Adenosine Triphosphatases