Non-hormone-induced mixed epithelial and stromal tumor of kidney in a man: description of a rare case.
Mixed epithelial and stromal tumor of the kidney is a recently recognized category of lesions occurring mostly in adult, middle-age women with a history of hormonal treatment. We present a rare case of a 58-year-old asymptomatic man without a history of hormonal treatment with a tumor characterized by proliferation of multiple cysts lined by single layers of epithelial cells and hypercellular stroma of spindle "ovarian-like" cells. Immunohistochemically, the stromal cells reacted against estrogen and progesterone receptors, vimentin, desmin, and CD34. A follow-up computed tomography scan performed 8 months after surgical enucleation of the lesion showed no signs of recurrence.
Colombo
Piergiuseppe
P
Department of Pathology, Istituto Clinico Humanitas-IRCCS, University of Milan School of Medicine, Rozzano Milan, Italy. piergiuseppe.colombo@humanitas.it
Naspro
Richard
R
Vallieri
Lucia
L
Vavassori
Ivano
I
Valenti
Sergio
S
Galli
Carlo
C
Roncalli
Massimo
M
D018952:Antigens, CD34 / Q000378:metabolism; D003893:Desmin / Q000378:metabolism; D005629:Frozen Sections; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D017154:Stromal Cells / Q000473:pathology*
D018952:Antigens, CD34; D003893:Desmin