Chemical and genetic diversity of Ligularia vellerea in Yunnan, China.
Intra-specific diversity in Liularia vellerea growing in the northwestern to central Yunnan province of China was studied by chemical and genetic approaches. Samples collected in the Jianchuan, Lijiang, and Zhongdian areas contained 6,15-dioxygenated furanoeremophilanes as their major components (type A); whereas samples from the Luguhu area accumulated 1,6-dioxygenated furanoeremophilanes (type B); a sample from near Kunming, however, contained 6,15-dioxygenated eremophilanolides (type C). 11 beta H- and 11 alpha H-6 beta-angeloyloxy-15-carboxyeremophil-7-en-12,8-olides (eremofarfugins D and E) were also isolated and their structures were determined. A correlation between the composition and the DNA sequence was observed in the ITSs.
Tori
Motoo
M
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. tori@ph.bunri-u.ac.jp
Nakamizo
Hiromi
H
Mihara
Kanako
K
Sato
Masahiko
M
Okamoto
Yasuko
Y
Nakashima
Katsuyuki
K
Tanaka
Masami
M
Saito
Yoshinori
Y
Sono
Masakazu
M
Gong
Xun
X
Shen
Yuemao
Y
Hanai
Ryo
R
Kuroda
Chiaki
C
D019659:Asteraceae / Q000737:chemistry* / Q000235:genetics*; D002681:China; D014644:Genetic Variation; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry / Q000235:genetics; D000081223:Polycyclic Sesquiterpenes; D017422:Sequence Analysis, DNA / Q000379:methods; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D013045:Species Specificity; D013237:Stereoisomerism
C530521:11alpha H-6 beta-angeloyloxy-15-carboxyeremophil-7-en-12,8-olide; D009281:Naphthalenes; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds