title: Landscape elements and Hantaan virus-related hemorrhagic fever with renal syndrome, People's Republic of China.
abstract: Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in the People's Republic of China, accounting for 90% of human cases reported globally. In this study, a landscape epidemiologic approach, combined with geographic information system and remote sensing techniques, was applied to increase our understanding of HFRS due to Hantaan virus and its relationship with landscape elements in China. The landscape elements considered were elevation, normalized difference vegetation index (NDVI), precipitation, annual cumulative air temperature, land surface temperature, soil type, and land use. Multivariate logistic regression analysis showed that HFRS incidence was remarkably associated with elevation, NDVI, precipitation, annual cumulative air temperature, semihydromorphic soils, timber forests, and orchards. These findings have important applications for targeting HFRS interventions in mainland China.
authors.affiliation: State Key Laboratory of Remote Sensing Science, IRSA/CAS, Beijing, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Yan
authors.forename: Li-Qun
authors.initials: LQ
authors.lastname: Fang
authors.forename: Hua-Guo
authors.initials: HG
authors.lastname: Huang
authors.forename: Long-Qi
authors.initials: LQ
authors.lastname: Zhang
authors.forename: Dan
authors.initials: D
authors.lastname: Feng
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Zhao
authors.forename: Wen-Yi
authors.initials: WY
authors.lastname: Zhang
authors.forename: Xiao-Wen
authors.initials: XW
authors.lastname: Li
authors.forename: Wu-Chun
authors.initials: WC
authors.lastname: Cao
mesh_terms: D000531:Altitude; D000818:Animals; D002681:China / Q000453:epidemiology; D002980:Climate; D017753:Ecosystem; D018063:Hantaan virus; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D051189:Murinae / Q000821:virology; D011891:Rain; D051381:Rats; D012307:Risk Factors; D013696:Temperature