title: Replacement of right coronary leaflet with bovine pericardium.
abstract: Bovine pericardium was used to replace the right coronary leaflet to manage aortic insufficiency resulting from ventricular septal defect in 6 patients aged 15 to 34 years. Aortic insufficiency was severe in 5 patients and moderate in one. In all patients, the ventricular septal defect was repaired before aortic valvuloplasty. They were followed up for 5 to 6 months. No mortality was observed. Three patients had relief of aortic insufficiency, 2 had mild residual aortic insufficiency, and one had minor insufficiency not requiring re-operation. Replacement of the right coronary leaflet with bovine pericardium is a promising technique for young patients. The short-term outcomes are encouraging, but longer follow-up is required to assess the durability and function of bovine pericardium in the aortic position.
authors.affiliation: Department of Cardiac Surgery, Wuhan Asia Heart Hospital, Wuhan, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Tao
authors.forename: Xiang-Jun
authors.initials: XJ
authors.lastname: Zeng
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D001705:Bioprosthesis; D002417:Cattle; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000601:surgery; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation*; D006801:Humans; D008297:Male; D010496:Pericardium / Q000637:transplantation*; D011474:Prosthesis Design; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome