title: Synthesis of functionalized oxazolones by a sequence of Cu(II)- and Au(I)-catalyzed transformations.
abstract: A study concerning a two-step sequence leading to the formation of diversely 1,5-disubstituted oxazolones is described. The mild conditions employed allow the efficient and rapid synthesis of a variety of such compounds via an initial Cu(II)-catalyzed coupling of a bromoalkyne with a secondary tert-butyloxycarbamate followed by a Au(I)-catalyzed cycloisomerization of the N-alkynyl tert-butyloxycarbamates thus obtained.
authors.affiliation: Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau, France.
authors.forename: Florin M
authors.initials: FM
authors.lastname: Istrate
authors.forename: Andrea K
authors.initials: AK
authors.lastname: Buzas
authors.forename: Igor Dias
authors.initials: ID
authors.lastname: Jurberg
authors.forename: Yann
authors.initials: Y
authors.lastname: Odabachian
authors.forename: Fabien
authors.initials: F
authors.lastname: Gagosz