Plasma concentrations of ascorbic acid in parturients from a hospital in Southeast Brazil.
OBJECTIVE
Pregnancy is a period characterized by high metabolic requirements and physiological changes in the female organism. During this period, low body stores of vitamins and minerals including antioxidants can have adverse effects on the mother and foetus. This cross-sectional study assessed plasma concentrations of ascorbic acid (AA) in 117 parturients admitted into a university hospital in São Paulo city, Brazil.


METHODS
The concentrations of AA were determined by the high performance liquid chromatographic method. Data concerning socioeconomic, demographic, obstetric and nutritional characteristics of the parturients were collected by a standardized questionnaire.


RESULTS
The prevalence of AA deficiency (<22.7 micromol/L) among the parturients was 30.8%. Mean plasma AA concentrations were lower in single/divorced women (27.84+/-3.48 micromol/L) compared with married/single with partner women (34.78+/-1.85 micromol/L) (p=0.047). Blood AA concentrations were significantly correlated with per capita income (r=0.36, p<0.001) and vitamin C-rich food intake score (r=0.42, p<0.001).


CONCLUSIONS
The high prevalence of hypovitaminosis C detected in this study is probably due to an inadequate intake of foods rich in vitamin C and low income. We alert to the need for increasing the intake of vitamin C-rich foods through educational programs, especially for low income populations.
Madruga de Oliveira
Andréia
A
Department of Nutrition, School of Public Health, University of Sao Paulo, Avenida Dr Arnaldo 715, Sao Paulo-SP, CEP-01246-904, Brazil. andmo@usp.br
Rondó
Patrícia Helen C
PH
Mastroeni
Silmara Silva
SS
Oliveira
Julicristie M
JM
D000328:Adult; D001205:Ascorbic Acid / Q000008:administration & dosage* / Q000097:blood*; D001206:Ascorbic Acid Deficiency / Q000453:epidemiology*; D001938:Brazil / Q000453:epidemiology; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D006801:Humans; D007182:Income; D017533:Marital Status; D009751:Nutritional Requirements; D009752:Nutritional Status; D036801:Parturition / Q000097:blood / Q000502:physiology; D011247:Pregnancy; D039401:Prenatal Nutritional Physiological Phenomena; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014815:Vitamins / Q000008:administration & dosage / Q000097:blood
D014815:Vitamins; D001205:Ascorbic Acid