[The feasibility study of endovascular reconstruction of aortic arch with modular branched stent-graft system in canine].
OBJECTIVE
To design and manufacture a modular branched stent-graft system of endovascular reconstruction of the aortic arch in canine, and to investigate the feasibility of endovascular repair.


METHODS
After the length and the diameter of ascending aorta, aortic arch and super-arch branched vessel measurement, a modular branched stent-graft system, including two pieces bifurcated stent-graft and one piece straight stent-graft, was designed and manufactured. Under X-ray fluorescope, these three modulars were accessed from right subclavian, left subclavian and femoral artery respectively and connected one by one to reconstruct the aortic arch. The shape and structure of stent-grafts, haemodynamics in aortic arch and endoleak were observed.


RESULTS
Eight of ten operations were completed successfully. Two dogs died of obstruction of coronary artery and artery rupture of left subclavian respectively during operation. In the eight successful cases, two proximal type I endoleaks were observed, and no other type endoleak occurred. The shape and the localization of stent-grafts were fine, and the coronary artery and carotid artery were unobstructed.


CONCLUSIONS
It is feasible to reconstruct aortic arch of canine by modular branched stent-graft, and it is significant to direct the research of reconstruction of human aortic arch.
Yang
Dai-hua
DH
Department of Vascular Surgery, the General Hospital of People's Liberation Army, Beijing 100853, China.
Guo
Wei
W
Liu
Xiao-ping
XP
Yin
Tai
T
Jia
Xin
X
Zhang
Hong-peng
HP
Wang
Wei
W
Zhang
Guo-hua
GH
Liang
Fa-qi
FQ
D000818:Animals; D001013:Aorta, Thoracic / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D004285:Dogs; D005240:Feasibility Studies; D008297:Male; D011474:Prosthesis Design; D015607:Stents