[Photodynamic visudyne therapy for subretinal neovascularization].
A total of 199 sessions of photodynamic therapy (PDT) with visudine were performed in 119 patients (227 eyes) at the Laser Center, T. I. Yeroshevsky Samara eye diseases hospital. Analysis of the changes occurring in visual function in the presence of the subretinal neovascular membrane developing in age-related macular dystrophy and high complicated myopia showed an increase in visual functions in the first 3-6 months after PDT, which is, in the authors' opinion, associated with the diminution of macular edema and the resolution of hemorrhage. In the subsequent months, visual acuity tended to slightly lower. The late follow-up periods (after 1.5 years) saw visual function stabilization. Visudine PDT for subretinal neovascularization is an effective, safe, technically simple, well-tolerable procedure that makes it possible not only to stabilize, but, in many cases, to improve visual functions. A follow-up of patients for as long as 18 months demonstrated that stable visual functions were retained with a slight tendency for their reduction during continued PDT sessions.
Zolotarev
A V
AV
Malyshev
A S
AS
Fadeeva
A V
AV
Morozova
Iu V
IuV
Podsevakina
T A
TA
D000328:Adult; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D000077362:Verteporfin; D014792:Visual Acuity
D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin