Squamous cell carcinoma arising in an ovarian mature cystic teratoma complicating pregnancy: a case report.
BACKGROUND
The question of whether patients with pure stage I squamous cell carcinoma in a mature cystic teratoma (MCT) should undergo conservative surgery, or postoperative adjuvant treatment remains unresolved.


METHODS
A 33-year-old woman with a left ovarian cyst underwent laparoscopic cystectomy at 16 weeks of gestation. Histological examination confirmed squamous cell carcinoma arising in an MCT. At 18 weeks of gestation, she underwent left salpingo-oophorectomy, and was diagnosed as having stage Ic malignant transformation of the MCT, and was observed closely without postoperative adjuvant chemotherapy. She delivered a healthy baby at 41 weeks of gestation. No evidence of recurrence was observed 14 months after the initial laparoscopic surgery.


CONCLUSIONS
Although a thorough staging procedure , histopathologic evaluation, and long-term follow-up are indispensable, patients with early stage I squamous cell carcinoma in MCT may safely undergo conservative surgery.
Mekaru
Keiko
K
Department of Obstetrics and Gynecology, Faculty of Medicine, University of the Ryukyus, 207 Uehara Nishihara, Okinawa, 903-0215, Japan.
Kamiyama
Shigeru
S
Masamoto
Hitoshi
H
Yagi
Chiaki
C
Hirakawa
Makoto
M
Inamine
Morihiko
M
Nagai
Yutaka
Y
Sakumoto
Kaoru
K
Aoki
Yoichi
Y
D000328:Adult; D000951:Antigens, Neoplasm / Q000097:blood; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000473:pathology* / Q000601:surgery; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007813:Laparotomy; D010051:Ovarian Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000097:blood / Q000473:pathology* / Q000601:surgery; D013724:Teratoma / Q000097:blood / Q000473:pathology* / Q000601:surgery
D000951:Antigens, Neoplasm