title: Occupation and lymphoid malignancies: results from a French case-control study.
abstract: OBJECTIVE
  Investigating relationships between potential occupational risk factors and lymphoid malignancy (LM).
  
  
  METHODS
  We conducted a multicenter hospital-based case-control study in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma, and "lymphoproliferative syndrome" and 752 frequency-matched controls. Data were collected through face-to-face standardized and detailed interviews.
  
  
  RESULTS
  Farming was significantly associated with NHL (odds ratio [OR] = 1.4 [1.0 to 2.0]) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR = 1.8 [1.2 to 2.7]) and HL (OR = 2.2 [1.0 to 4.7]). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association.
  
  
  CONCLUSIONS
  The results support the hypothesis that farming plays a role in most types of LM.
authors.affiliation: INSERM, U754, Villejuif Cedex, France. orsi@vjf.inserm.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: Orsi
authors.forename: Xavier
authors.initials: X
authors.lastname: Troussard
authors.forename: Alain
authors.initials: A
authors.lastname: Monnereau
authors.forename: Christian
authors.initials: C
authors.lastname: Berthou
authors.forename: Pierre
authors.initials: P
authors.lastname: Fenaux
authors.forename: Gerald
authors.initials: G
authors.lastname: Marit
authors.forename: Pierre
authors.initials: P
authors.lastname: Soubeyran
authors.forename: Françoise
authors.initials: F
authors.lastname: Huguet
authors.forename: Noel
authors.initials: N
authors.lastname: Milpied
authors.forename: Michel
authors.initials: M
authors.lastname: Leporrier
authors.forename: Denis
authors.initials: D
authors.lastname: Hemon
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Clavel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004651:Employment / Q000706:statistics & numerical data; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008223:Lymphoma / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000453:epidemiology*; D016273:Occupational Exposure / Q000706:statistics & numerical data*; D009790:Occupations / Q000706:statistics & numerical data*; D012307:Risk Factors