Fecal viral concentration and diarrhea in norovirus gastroenteritis.
Fecal viral concentrations of 40 patients infected with norovirus genogroup GII.4 correlated with diarrhea duration and frequency of vomiting. Higher viral concentration and older age were independently associated with prolonged diarrhea (> or =4 days). These findings provide information on the pathogenesis and transmission of norovirus infections.
Lee
Nelson
N
Prince of Wales Hospital, Hong Kong Special Administrative Region, People's Republic of China.
Chan
Martin C W
MC
Wong
Bonnie
B
Choi
K W
KW
Sin
Winnie
W
Lui
Grace
G
Chan
Paul K S
PK
Lai
Raymond W M
RW
Cockram
C S
CS
Sung
Joseph J Y
JJ
Leung
Wai K
WK
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017250:Caliciviridae Infections / Q000821:virology*; D018076:DNA, Complementary / Q000302:isolation & purification; D004279:DNA, Viral / Q000302:isolation & purification; D003967:Diarrhea / Q000821:virology*; D005243:Feces / Q000821:virology*; D005260:Female; D005759:Gastroenteritis / Q000821:virology*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000235:genetics / Q000302:isolation & purification*
D018076:DNA, Complementary; D004279:DNA, Viral