Respiratory training with a specific device in cystic fibrosis: a prospective study.
BACKGROUND
Chest physiotherapy (CP) is used in cystic fibrosis (CF) even if there is no robust scientific evidence of a beneficial effect. We investigated the effects of a training with a specific device (SpiroTiger) in a group of CF patients. This device, developed for respiratory training through maximal inspirations and espirations without hypocarbia, may improve respiratory function and mucus clearance. Patients where instructed and trained by a physiotherapist with individualized settings of training parameters.


METHODS
Twenty-four patients were enrolled in an open-label 1 year observational study. Baseline and post intervention measurements were determined by lung function (FVC, FEV1, FEF 25-75), patients' opinions on physiotherapy (questionnaires), need for antibiotic treatment (clinical follow-up and records) and perception of physical fitness (questionnaires) in the year before and in the year of intervention. Adherence to physiotherapy was monitored by means of a specific device software.


RESULTS
Increased lung function (FEV1 p<0.01), perception of physical fitness (p<0.001) and a reduction in the need for intravenous antibiotic treatment (p<0.001) were reported. Adherence to treatment was good/acceptable in 92% of patients.


CONCLUSIONS
This study shows an association between training through a specific device and improved lung function. Further trials are needed to confirm this report.
Sartori
R
R
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
Barbi
E
E
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
Poli
F
F
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
Ronfani
L
L
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
Marchetti
F
F
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
Amaddeo
A
A
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy. Electronic address: alessandro.amaddeo@gmail.com.
Ventura
A
A
Clinica Pediatrica, IRCCS Burlo Garofolo, University of Trieste, Via dell'Istria 65/1, 34100, Trieste Italy.
D000293:Adolescent; D000328:Adult; D001945:Breathing Exercises; D003550:Cystic Fibrosis / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012129:Respiratory Function Tests; D012138:Respiratory Therapy / Q000295:instrumentation*; D016896:Treatment Outcome; D055815:Young Adult