Intramolecular acid-base catalysis of a phosphate diester: modeling the ribonuclease mechanism.
Orth
Elisa S
ES
Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil.
Brandão
Tiago A S
TA
Milagre
Humberto M S
HM
Eberlin
Marcos N
MN
Nome
Faruk
F
D000143:Acids / Q000737:chemistry*; D001665:Binding Sites; D002384:Catalysis; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007093:Imidazoles / Q000737:chemistry*; D007700:Kinetics; D008954:Models, Biological; D008958:Models, Molecular; D015394:Molecular Structure; D010755:Organophosphates / Q000737:chemistry*; D009943:Organophosphorus Compounds; D010710:Phosphates / Q000737:chemistry*; D012259:Ribonuclease, Pancreatic / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D013237:Stereoisomerism; D053719:Tandem Mass Spectrometry / Q000379:methods
D000143:Acids; D007093:Imidazoles; D010755:Organophosphates; D009943:Organophosphorus Compounds; D010710:Phosphates; C527956:bis(2-(1-methyl-1H-imidazolyl)phenyl)phosphate; D012259:Ribonuclease, Pancreatic