Development of a National TMJ Implant Registry and Repository-- NIDCR's TIRR.
OBJECTIVE
To provide a national systematic program to collect removed TMJ implants and biological tissues, make them available to researchers, and study them in conjunction with long-term clinical follow-up, with the ultimate goal of stimulating research toward understanding the safety and outcomes of TMJ implants.


METHODS
Two synchronized divisions: The Registry, recruiting clinicians and/or surgeons and patients, and collecting comprehensive clinical patient data over time; the Repository, procuring and archiving high quality, well characterized biological specimens and retrieved implants for dissemination.


METHODS
Clinicians, surgeons, patients, researchers, pilot studies.


RESULTS
October 2002-present: Recruited 34 TMJ surgeons, 34 TMJ clinicians; registered 723 surgical/non-surgical TMJD patients and control subjects; collected 542 specimens, blood, saliva; initiated 19 projects using TIRR resources; produced 60 publications and presentations nationally and internationally; sent ten grants into review, with more being developed.
Continuing collection of long-term data for the development of new and improved implant designs and materials and investigation into understanding pathological mechanisms of TMJD.
Myers
Sandra
S
NIDCR's TIRR Laboratory, Department of Diagnostic & Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, Minnesota 55455, USA.
Kaimal
Shanti
S
Springsteen
Jennifer
J
Ferreira
Joao
J
Ko
Ching-Chang
CC
Fricton
James
J
D019992:Databases as Topic; D018865:Dental Research; D020878:Device Removal; D004869:Equipment Safety; D005500:Follow-Up Studies; D006801:Humans; D007595:Joint Prosthesis; D008137:Longitudinal Studies; D008910:Minnesota; D054584:National Institute of Dental and Craniofacial Research (U.S.); D010865:Pilot Projects; D011475:Prosthesis Failure; D012042:Registries; D012575:Schools, Dental; D013704:Temporomandibular Joint / Q000601:surgery; D013705:Temporomandibular Joint Disorders / Q000601:surgery; D016896:Treatment Outcome; D014481:United States