[Can garlic (Allium sativum) extract be used as scolocidal agent?].
Garlic (Allium sativum L.) has been used in the public health in some of treatments for years. The most important chemical compounds of garlic are sulphide (alisin, ajoen and diallysulphure) compounds. Allisin is described as antibacterial, antifungal, antiparasitic and anticarsinogenic agent and many works practice on it. But its antiscolocidal effect has not been worked yet. In our work, whether garlic extract has effects both direct and daughter vesicules to protoscolex is searched. In the study during the surgery daughter vesicules and protoscolex which are acquired from liver cyst hydatique and extracts which obtained from garlic grown in the Kastamonu region are used. Viability determination is work at using 0.1% eozin solution. In 50% mg/ml concentration garlic extract to protoscolex' in 15 minutes, in 25% mg/ml concentration 20. minutes and 12.5% mg/ml concentration in 30 minutes have full effect. While it has full effect in 20. minutes to protoscolex into the vesicules within the 50% mg/ml 12.5 mg/ml concentration, there has been 80% viability in 40 minutes.
Ozçelik
Semra
S
Cumhuriyet Universitesi Tip Fakültesi Parazitoloji Anabilim Dali, Sivas, Turkey. sozcelik@cumhuriyet.edu.tr
Sümer
Zeynep
Z
Değerli
Serpil
S
Ozan
Fatih
F
Sökmen
Atalay
A
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D002589:Cestoda / Q000187:drug effects*; D005737:Garlic / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D013440:Sulfides / Q000494:pharmacology
D000871:Anthelmintics; D010936:Plant Extracts; D013440:Sulfides