Mechanical response of brain to mechanical stimuli--animal model investigation.
OBJECTIVE
Conventional neurosurgical procedures give surgeons both tactile and visual feedback. Unlike conventional procedures, minimally invasive surgery is devoid of haptic feedback. Incorporation of tactile feedback into neurosurgical robotic systems can greatly enhance the results of minimally invasive procedures. Hence, the ultimate goal of the research presented here is to define the force response of the brain to different types of mechanical stimuli (short- and long-term). The experimental results describe the force responses of brain during indentation tests.


METHODS
Seven ovine head specimens with exposed brain were fixed to an MTS Synergie 100 testing machine using a rigid clamp--metallic frame with sharp-end screws. Four regions were loaded by a hemispherically-ended cylindrical indentor. Each of the indentations applied to the brain was divided into two general stages: insertion and hold which was constant for 180 s. Measurements for the following 3 loading velocities were conducted. The force response of brain to mechanical stimulus was acquired for each case.


RESULTS
The force response of brain to short-term mechanical stimulus depends on both loading velocities and regions of indentation, whereas the long-term force response depends on the history of loadings.


CONCLUSIONS
The development of minimally invasive neurosurgical systems requires estimation of the mechanical response of brain to contact with surgical devices. For this reason, investigation of the force response of brain employing different boundary conditions is necessary.
Szotek
Sylwia
S
Division of Biomedical Engineering and Experimental Mechanics, Institute of Machine Design and Operation, Faculty of Mechanical Engineering, Wrocław University of Technology, Wrocław, Poland. sylwia.szotek@pwr.wroc.pl
Kobielarz
Magdalena
M
Maksymowicz
Krzysztof
K
D000818:Animals; D001696:Biomechanical Phenomena; D001921:Brain / Q000503:physiopathology* / Q000601:surgery*; D004548:Elasticity; D005246:Feedback; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D023421:Models, Animal; D008959:Models, Neurological; D010812:Physical Stimulation / Q000379:methods; D012371:Robotics; D012756:Sheep; D013314:Stress, Mechanical; D013525:Surgical Instruments; D013718:Tensile Strength