title: [Study on anticancer effect in vivo of active fraction from Nervilia fordii].
abstract: OBJECTIVE
  To determine the active fraction with anticancer effect in vivo from Nervilia fordii.
  
  
  METHODS
  The effective petroleum ether extract and ethyl acetate extract parts preliminary were selected in vitro, then anticancer experiments in vivo were done by S180-mice and H22-mice models.
  
  
  RESULTS
  Petroleum ether extract and ethyl acetate extract parts both had obvious anticancer effects to S180-mice and H22-mice, and could prolong H22-mice life. Meanwhile, they could improve the immunoloregulation of mice.
  
  
  CONCLUSIONS
  It is the first time that the petroleum ether extract and ethyl acetate extract of Nervilia foadii are proved to be the effective anticancer fractions in vivo. On this basis, the further studies are needed on active principles or principle group with anticancer effect and the characteristics of this effect in Nervilia foadii.
authors.affiliation: Guangxi College of Traditional Chinese Medicine, Nanning 530001, China. 8zhen@163.com
authors.forename: Han-shen
authors.initials: HS
authors.lastname: Zhen
authors.forename: Yan-yuan
authors.initials: YY
authors.lastname: Zhou
authors.forename: Ye-fei
authors.initials: YF
authors.lastname: Yuan
authors.forename: Zhen-guo
authors.initials: ZG
authors.lastname: Zhong
authors.forename: Chen-yan
authors.initials: CY
authors.lastname: Liang
authors.forename: Qin
authors.initials: Q
authors.lastname: Qiu
mesh_terms: D000085:Acetates; D000473:Alkanes; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000627:therapeutic use*; D005260:Female; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D008297:Male; D051379:Mice; D029595:Orchidaceae / Q000737:chemistry*; D009929:Organ Size / Q000187:drug effects; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D012510:Sarcoma 180 / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D013154:Spleen / Q000187:drug effects / Q000473:pathology; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology
chemical_list: D000085:Acetates; D000473:Alkanes; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; C007650:ethyl acetate; C004544:naphtha