Vaccinations in children treated with standard-dose cancer therapy or hematopoietic stem cell transplantation.
Most children with cancer are immunocompromised during therapy and for a variable period after completion of therapy. They are at an increased risk of infections, including vaccine-preventable infections. There is a reduction in immunity to vaccine-preventable diseases after completion of standard-dose chemotherapy and after hematopoietic stem cell transplant. It is important to protect these children against vaccine-preventable diseases by reimmunization.
Patel
Soonie R
SR
Paediatric Department, Mayday University Hospital, Croydon, UK. soonie.patel@mayday.nhs.uk
Chisholm
Julia C
JC
Heath
Paul T
PT
D002648:Child; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007115:Immunization Schedule; D016867:Immunocompromised Host; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*; D012307:Risk Factors; D014611:Vaccination / Q000009:adverse effects*