The anti-inflammatory effects of nebivolol in human coronary smooth muscle cells: clinical implications.
Given that the majority of hypertensives require more than one drug to control blood pressure, the pleitropic effects (especially anti-inflammatory effects) and favourable metabolic profile of nebivolol could make it an alternative drug regimen for hypertensives requiring beta-blocker treatment. Although standard beta-blockers seem to have a hard time at present, we are convinced that perhaps the new generation beta-blockers such as nebivolol might yet 'rescue' the reputation of beta blockers in the near-future.
Celik
Turgay
T
Iyisoy
Atila
A
Kardesoglu
Ejder
E
Fici
Francesco
F
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D001578:Benzopyrans / Q000494:pharmacology* / Q000627:therapeutic use; D003331:Coronary Vessels / Q000187:drug effects* / Q000502:physiology; D004983:Ethanolamines / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000502:physiology; D032389:Myocytes, Smooth Muscle / Q000187:drug effects* / Q000502:physiology; D000068577:Nebivolol
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001578:Benzopyrans; D004983:Ethanolamines; D000068577:Nebivolol