title: Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects.
authors.affiliation: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Murkin
authors.forename: Peter C
authors.initials: PC
authors.lastname: Tyler
authors.forename: Vern L
authors.initials: VL
authors.lastname: Schramm
mesh_terms: D001667:Binding, Competitive; D006801:Humans; D007288:Inosine / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D011684:Purine Nucleosides / Q000737:chemistry / Q000378:metabolism; D011683:Purine-Nucleoside Phosphorylase / Q000737:chemistry* / Q000378:metabolism*; D011744:Pyrimidinones / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics; D014316:Tritium
chemical_list: D011684:Purine Nucleosides; D011744:Pyrimidinones; D014316:Tritium; C113101:forodesine; D007288:Inosine; D011683:Purine-Nucleoside Phosphorylase