title: Primary osteogenic sarcoma of breast detected on Tc-99m MIBI scintigraphy and Tc-99m MDP skeletal scintigraphy.
abstract: A 64-year-old woman presented with a painless breast mass. Tc-99m methoxyisobutylisonitrile scintigraphy of both breasts showed a local area of abnormal uptake in the left breast in 5 min and 2 h. A skeletal scan showed very intense concentration of activity in the primary breast tumor in the left breast. A left mastectomy and an axillary dissection were performed. The predominant histologic type of the mass was an osteosarcoma, and the diagnosis of a primary osteogenic sarcoma of the breast was made. Primary osteogenic sarcoma of the breast is rare and represents less than 1% of all primary breast malignancies.
authors.affiliation: Nuclear Medicine Department, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xuanwu District, Beijing, 100050, China. nmyangjigang@yahoo.com.cn
authors.forename: Ji-Gang
authors.initials: JG
authors.lastname: Yang
authors.forename: Chun-Lin
authors.initials: CL
authors.lastname: Li
authors.forename: Rui-Rui
authors.initials: RR
authors.lastname: Hao
authors.forename: Lan-Fang
authors.initials: LF
authors.lastname: Zou
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012516:Osteosarcoma / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D035583:Rare Diseases / Q000000981:diagnostic imaging; D013669:Technetium Tc 99m Medronate; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013669:Technetium Tc 99m Medronate