title: [Dimenhydrinate overdosage in a 3(1/2) year-old-girl with dilative cardiomyopathy].
abstract: Dimenhydrinate overdosage in a 3(1/2) year-old-girl with dilative cardiomyopathy. Dimenhydrinate (Vomex(R)) is frequently used in the treatment of sickness and vomiting. The symptoms of overdosage present like an anticholinergic syndrome. We report on the clinical findings of an intoxication with dimenhydrinate in a 3(1/2) year-old-girl with functional dilative cardiomyopathy following a congenital left ventricular diverticle. Especially in small children, with the application of 40 mg suppositories once or twice per day the maximum dose of 3.75 mg/kgBW/d is achieved.
authors.affiliation: Universitätsklinik für Kinder- und Jugendmedizin, Pädiatrische Intensivstation, Tübingen. monika.girisch@med.uni-tuebingen.de
authors.forename: M
authors.initials: M
authors.lastname: Girisch
authors.forename: M
authors.initials: M
authors.lastname: Hofbeck
authors.forename: R
authors.initials: R
authors.lastname: Rauch
authors.forename: C
authors.initials: C
authors.lastname: Apitz
authors.forename: L
authors.initials: L
authors.lastname: Sieverding
mesh_terms: D000932:Antiemetics / Q000008:administration & dosage / Q000506:poisoning*; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D002675:Child, Preschool; D004111:Dimenhydrinate / Q000008:administration & dosage / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D013488:Suppositories; D013997:Time Factors
chemical_list: D000932:Antiemetics; D013488:Suppositories; D004111:Dimenhydrinate