Effects of bioactive tetrapeptides on free-radical processes.
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
Kozina
L S
LS
St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of Russian Academy of Medical Sciences. milarozina@mail.ru
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000097:blood; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D009842:Oligopeptides / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000097:blood
D000975:Antioxidants; D005609:Free Radicals; D009842:Oligopeptides; C431545:alanyl-glutamyl-aspartylprolyine; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; C421253:alanyl-glutamyl-aspartyl-glycine