New cycloartane glycosides from Camptosorus sibiricus Rupr.
Two new cycloartane glycosides were isolated from the whole herbs of Camptosorus sibiricus Rupr. By means of chemical and spectroscopic methods (IR, 1D and 2D NMR, HRMS, ESI MS), the structures were established as (24R)-3beta, 7beta, 24, 25-tetrahydroxycycloartane 3-O-beta-D-glucopyranosyl-24-O-beta-D-glucopyranoside (1) and (24R)-3beta, 7beta, 24, 25-tetrahydroxycycloartane 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-24-O-beta-D-glucopyranoside (2). At the same time, two new compounds were tested for their cytotoxicities in vitro against human tumor cell lines (A375-S2, Hela).
Li
Ning
N
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Li
Xian
X
Li
Xue-Zheng
XZ
Zhang
Peng
P
Meng
Da-Li
DL
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D029624:Ferns / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
C517937:3beta,7beta,24beta,25,30-pentahydroxycycloartane-3-O-beta-D-glucopyranoside-24-O-beta-D-glucopyranosyl(1-2)-D-glucopyranoside; D000972:Antineoplastic Agents, Phytogenic; D006027:Glycosides; D012503:Saponins; D014315:Triterpenes