Use of natural products in anticytokine therapy.
This work was designed to study direct anticytokine activity of natural products on the cell model of inflammation. We developed a combination of medicinal plants (calendula, elder, and pansy) with maximum antiinflammatory activity. This combination can be used for pathogenetic therapy of various inflammatory diseases, including atherosclerosis.
Gorchakova
T V
TV
Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences. t-gorchakova@mail.ru
Suprun
I V
IV
Sobenin
I A
IA
Orekhov
A N
AN
D050197:Atherosclerosis / Q000188:drug therapy; D002478:Cells, Cultured; D016207:Cytokines / Q000037:antagonists & inhibitors*; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D018836:Inflammation Mediators / Q000037:antagonists & inhibitors / Q000097:blood / Q000378:metabolism; D007375:Interleukin-1 / Q000037:antagonists & inhibitors / Q000097:blood / Q000378:metabolism; D009000:Monocytes / Q000187:drug effects / Q000276:immunology; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000097:blood / Q000378:metabolism
D016207:Cytokines; D018836:Inflammation Mediators; D007375:Interleukin-1; D010936:Plant Extracts; D014409:Tumor Necrosis Factor-alpha