[Chest pain in a woman previously treated with irradiation].
A 34-year-old woman developed chest pain during exercise. She had been treated for Hodgkin lymphoma with irradiation (mantle field) and cytotoxic drugs (ABVD) 15 years earlier, and had risk factors for coronary artery disease (smoker status and family history). An exercise ECG showed significant ST depressions and an echocardiogram was normal. She underwent coronary angiography, which revealed three vessel disease (including stenosis of the left main stem); bypass grafting was successfully performed. This case illustrates the fact that even young women may develop extensive coronary disease and that development of coronary artery disease may be accelerated after irradiation of the thorax.
Hovland
Anders
A
Kardiologisk seksjon, Medisinsk avdeling, Nordlandssykehuset Bodø, 8092 Bodø. a-hovlan@online.no
Bjørnstad
Hanne
H
Ytre-Arne
Kjetil
K
Maisenholder
Martin
M
Vik-Mo
Harald
H
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002637:Chest Pain / Q000175:diagnosis*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D023921:Coronary Stenosis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D003937:Diagnosis, Differential; D004452:Echocardiography; D005080:Exercise Test; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D011878:Radiotherapy / Q000009:adverse effects*; D012307:Risk Factors