[Succesful collaborations between three Mexican institutions for research on dislipidemias, obesity and diabetes].
OBJECTIVE
To describe the contributions ofthree Mexican institutions (Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Universidad Nacional Autónoma de México and the Centro de Encuestas Nacionales de Salud of the Instituto Nacional de Salud Pública) in the study, of chronic degenerative disorders.


RESULTS
The most relevant group contributions include: the identification of a risk allele for metabolic syndrome and diabetes, specific for the Mexican population (the R230C variant of the ABC-A1 transporter); the design and validation of a population-based definition of metabolic syndrome which is useful to predict the risk of incident diabetes; the description of the molecular epidemiology of familial hypercholesterolemia in Mexico and the identification of several loci associated with familial combined hyperlipidemia. In addition, members of these institutions have participated in the description of the epidemiology of diabetes, metabolic syndrome and lipid abnormalities.


CONCLUSIONS
The complementary approach of these research groups has facilitated successful collaborations. Our results will be useful for the future development of diagnostic tests and preventive programs.
Aguilar-Salinas
Carlos A
CA
Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México DF, México. caguilarsalinas@yahoo.com
Canizales-Quinteros
Samuel
S
Rojas-Martínez
Rosalba
R
García-García
Eduardo
E
Olaiz-Fernández
Gustavo
G
Gómez-Pérez
Francisco J
FJ
Tusié-Luna
María Teresa
MT
D000328:Adult; D000368:Aged; D003299:Cooperative Behavior; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000235:genetics; D050171:Dyslipidemias / Q000453:epidemiology / Q000235:genetics; D005260:Female; D006801:Humans; D007373:Interinstitutional Relations; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000235:genetics; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology / Q000235:genetics