title: Three-dimensional tumor localization in thick tissue with the use of diffuse photon-density waves.
abstract: A new approach to three-dimensional tumor localization in turbid media with the use of measurements in a single plane is presented. Optical diffuse photon-density waves are used to probe the turbid medium. Relative amplitudes and phases are measured in the detection plane. Lateral localization is accomplished in the detection plane. With a Fourier optics approach, the scattered wave is reconstructed throughout the volume to provide depth localization. Computer-simulation results that validate this technique are presented. Applications of this technique to multiple tumors and to optical mammography are discussed.
authors.forename: C L
authors.initials: CL
authors.lastname: Matson
authors.forename: N
authors.initials: N
authors.lastname: Clark
authors.forename: L
authors.initials: L
authors.lastname: McMackin
authors.forename: J S
authors.initials: JS
authors.lastname: Fender