Drug-induced paraparotid fat deposition in patients with HIV: case reports.
BACKGROUND
The treatment of patients with HIV is managed effectively with highly active antiretroviral therapy, but complications in the form of a lipodystrophy syndrome (LDS) often develop.


METHODS
. The authors describe two patients who had bilateral parotid area fatty swellings, which are a manifestation of the fat redistribution seen in LDS. Fat hypertrophy, fat atrophy or both in other regions; dyslipidemia; and glucose abnormalities also were present.


CONCLUSIONS
Although the LDS in patients with HIV is recognized visibly by fat redistribution, the syndrome includes dyslipidemia and insulin resistance. Dental visits give dentists the opportunity to recognize HIV-related cervicofacial fat alterations. For appropriate attention, referral to the patient's physician who is managing the HIV is indicated.
Mandel
Louis
L
Salivary Gland Center, and Division of Oral and Maxillofacial Surgery, Columbia University College of Dental Medicine, 630 West 168th Street, New York City, NY 10032, USA.
Alfi
David
D
D000273:Adipose Tissue / Q000187:drug effects*; D023241:Antiretroviral Therapy, Highly Active; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000188:drug therapy; D039682:HIV-Associated Lipodystrophy Syndrome / Q000139:chemically induced*; D006801:Humans; D006943:Hyperglycemia / Q000150:complications; D015228:Hypertriglyceridemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000139:chemically induced*; D014057:Tomography, X-Ray Computed