title: EPACT II: project and methods.
abstract: Building on the first European Panel on the Appropriateness of Crohn's Disease Treatment (EPACT I) which was held in Lausanne at the beginning of March 2004, a new panel will be convened in Switzerland (EPACT II, November to December 2007) to update this work. A combined evidence- and panel-based method (RAND) will be applied to assess the appropriateness of therapy for Crohn's disease (CD). In preparation for the meeting of experts, reviews of evidence-based literature were prepared for major clinical presentations of CD. During the meeting, an international multidis- ciplinary panel that includes gastroenterologists, surgeons and general practitioners weigh the strength of evidence and apply their clinical experience when assessing the appropriateness of therapy for 569 specific indications (clinical scenarios). This chapter describes in detail the process of updating the literature review and the systematic approach of the RAND Appropriateness Method used during the expert panel meeting.
authors.affiliation: Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland. pascal.juillerat@chuv.ch
authors.forename: Pascal
authors.initials: P
authors.lastname: Juillerat
authors.forename: Florian
authors.initials: F
authors.lastname: Froehlich
authors.forename: Christian
authors.initials: C
authors.lastname: Felley
authors.forename: Valérie
authors.initials: V
authors.lastname: Pittet
authors.forename: Christian
authors.initials: C
authors.lastname: Mottet
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Gonvers
authors.forename: Pierre
authors.initials: P
authors.lastname: Michetti
authors.forename: John-Paul
authors.initials: JP
authors.lastname: Vader
mesh_terms: D003424:Crohn Disease / Q000628:therapy*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005060:Europe; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D016730:Program Development; D011785:Quality Assurance, Health Care / Q000379:methods*; D013557:Switzerland