Antibacterial and antifungal activities of andrachne cordifolia muell.
The crude methanolic extract of Andrachne cordifolia Muell. (Euphorbiaceae) and its various fractions in different solvent systems (chloroform, ethyl acetate and n-butanol) were screened for antibacterial and antifungal activities. Crude extract and subsequent fractions demonstrated moderate to excellent antibacterial activities against the tested pathogens. Highest antibacterial activity was displayed by both chloroform and ethyl acetate fractions (100%) followed by the crude extract (68%) against Salmonella typhi. Similarly, crude extract and its subsequent fractions showed mild to excellent activities in antifungal bioassay with maximum (76%) antifungal activity against Microsporum canis by the chloroform fraction followed by the crude extract (65%).
Ahmad
Bashir
B
Department of Pharmacy, University of Peshawar, Pakistan. Bashirdr2001@yahoo.com
Hassan Shah
S M
SM
Bashir
Shumaila
S
Nisar
Muhammad
M
Chaudry
M Iqbal
MI
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D019684:Magnoliopsida / Q000737:chemistry*; D050296:Microbial Viability / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts