title: Intramolecular acid-base catalysis of a phosphate diester: modeling the ribonuclease mechanism.
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil.
authors.forename: Elisa S
authors.initials: ES
authors.lastname: Orth
authors.forename: Tiago A S
authors.initials: TA
authors.lastname: Brandão
authors.forename: Humberto M S
authors.initials: HM
authors.lastname: Milagre
authors.forename: Marcos N
authors.initials: MN
authors.lastname: Eberlin
authors.forename: Faruk
authors.initials: F
authors.lastname: Nome
mesh_terms: D000143:Acids / Q000737:chemistry*; D001665:Binding Sites; D002384:Catalysis; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007093:Imidazoles / Q000737:chemistry*; D007700:Kinetics; D008954:Models, Biological; D008958:Models, Molecular; D015394:Molecular Structure; D010755:Organophosphates / Q000737:chemistry*; D009943:Organophosphorus Compounds; D010710:Phosphates / Q000737:chemistry*; D012259:Ribonuclease, Pancreatic / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D013237:Stereoisomerism; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D000143:Acids; D007093:Imidazoles; D010755:Organophosphates; D009943:Organophosphorus Compounds; D010710:Phosphates; C527956:bis(2-(1-methyl-1H-imidazolyl)phenyl)phosphate; D012259:Ribonuclease, Pancreatic