title: Hematopoietic stem cell transplantation for autoimmune diseases: what have we learned?
abstract: Numerous individuals and institutions throughout the world have contributed to the development of hematopoietic stem cell transplantation (HSCT) for autoimmune diseases. In this review, we will summarize what we have learned at our own institution (Northwestern University), and how it has guided our therapy. An emphasis will be placed on both the scientific basis for the development of autologous hematopoietic stem cell transplantation and a summary of the data in a variety of human diseases.
authors.affiliation: Division of Immunotherapy, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. rburt@northwestern.edu
authors.forename: Richard K
authors.initials: RK
authors.lastname: Burt
authors.forename: Alessandro
authors.initials: A
authors.lastname: Testori
authors.forename: Alessandro
authors.initials: A
authors.lastname: Testor
authors.forename: Robert
authors.initials: R
authors.lastname: Craig
authors.forename: Bruce
authors.initials: B
authors.lastname: Cohen
authors.forename: Robert
authors.initials: R
authors.lastname: Suffit
authors.forename: Walter
authors.initials: W
authors.lastname: Barr
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology / Q000628:therapy*; D016207:Cytokines / Q000276:immunology / Q000378:metabolism; D006086:Graft vs Host Disease; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D036102:Peripheral Blood Stem Cell Transplantation; D019172:Transplantation Conditioning; D014182:Transplantation, Autologous
chemical_list: D016207:Cytokines; D007166:Immunosuppressive Agents