Identification of proteins in complex mixtures using liquid chromatography and mass spectrometry.
Liquid chromatography techniques have been successfully coupled with mass spectrometers to provide a robust method for the identification of proteins in mixtures. Chromatography can be performed in-line with the mass spectrometer and data acquisition can be directly interfaced with search algorithms for identification by correlation with databases.
Delahunty
Claire
C
The Scripps Research Institute, La Jolla, California, USA.
Yates
John R
JR
D002853:Chromatography, Liquid / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods*; D010455:Peptides / Q000032:analysis / Q000737:chemistry; D011506:Proteins / Q000032:analysis / Q000737:chemistry*
D010455:Peptides; D011506:Proteins