title: The clinical picture of uncomplicated versus complicated diverticulitis of the colon.
abstract: OBJECTIVE
  There is no consensus about the correct definition of uncomplicated diverticulitis (UD) in clinical practice. We evaluated therefore whether clinical picture of UD differs from complicated diverticulitis (CD). Fifty consecutive eligible patients (21 males, 29 females, mean age 63.6 years, range 47-75 years) were studied. Symptoms, the inflammatory indices, and Computerized Tomography (CT) scan of the abdomen were assessed at the time of admission.
  
  
  RESULTS
  Thirty-nine patients classified were affected by UD and 11 patients by CD. CD patients showed more severe clinical picture than UD and required urgent Hospital admission. Conversely, most of the patients affected by UD were treated as outpatients. CD patients showed higher symptom scores than UD patients, except the parameter "diarrhea". All CD patients showed increases in all inflammatory indices. Conversely, all UD patients showed increased ESR, CRP and fibrinogen, but WBC and alpha1-acid glycoprotein were increased in only a few cases. CT scan in CD patients always showed signs of severe colonic and pericolonic inflammation. Conversely, UD patients often showed moderate localized signs of inflammation without complication.
  
  
  CONCLUSIONS
  Clinical, laboratory, and radiological findings may easily differentiate uncomplicated from complicated diverticulitis of the colon. This integrated approach may be helpful in clinical settings.
authors.affiliation: Digestive Endoscopy Unit, Lorenzo Bonomo Hospital, Via Torino 49, Andria, BA, Italy. antotursi@tiscali.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Tursi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Brandimarte
authors.forename: Gianmarco
authors.initials: G
authors.lastname: Giorgetti
authors.forename: Walter
authors.initials: W
authors.lastname: Elisei
authors.forename: Michele
authors.initials: M
authors.lastname: Maiorano
authors.forename: Fabio
authors.initials: F
authors.lastname: Aiello
mesh_terms: D000368:Aged; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D003106:Colon / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004239:Diverticulitis, Colonic / Q000145:classification* / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D005340:Fibrinogen; D002097:C-Reactive Protein