Three-dimensional cross-linked F-actin networks: relation between network architecture and mechanical behavior.
Numerical simulations are reported for the response of three-dimensional cross-linked F-actin networks when subjected to large deformations. In addition to the physiological parameters such as actin and cross-linker concentration, the model explicitly accounts for filament properties and network architecture. Complementary to two-dimensional studies, we find that the strain-stiffening characteristics depend on network architecture through the local topology around cross-links.
Huisman
E M
EM
Micromechanics of Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, NL-9747 AG Groningen, The Netherlands.
van Dillen
T
T
Onck
P R
PR
Van der Giessen
E
E
D000199:Actins / Q000737:chemistry* / Q000378:metabolism; D001696:Biomechanical Phenomena; D055592:Biophysical Phenomena; D001703:Biophysics; D008956:Models, Chemical
D000199:Actins