title: [The use of fluorescent liposomal immunoanalysis for the diagnostics and indication of glanders and melioidosis].
abstract: The authors have developed a homogenous method for the detection of the cells, surface antigen, and Ag8 of glanders and melioidosis pathogens and antibodies to them, based on the compliment-dependent lysis of Ag8-sensitized liposomes. The method is highly specific; its sensitivity to antibodies to glanders and melioidosis pathogens is 24 to 440 times higher than that of RID: its sensitivity to Ag8 is 100 ng/ml corresponding to 1.25x10-10 M, and its sensitivity to cells is 10(5) to 10(6) cells/ml).
authors.forename: S N
authors.initials: SN
authors.lastname: Skopinskaia
authors.forename: S P
authors.initials: SP
authors.lastname: Iarkov
authors.forename: E N
authors.initials: EN
authors.lastname: Khramov
authors.forename: N P
authors.initials: NP
authors.lastname: Khrapova
authors.forename: N N
authors.initials: NN
authors.lastname: Piven'
authors.forename: E V
authors.initials: EV
authors.lastname: Prokhvatilova
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D042726:Burkholderia mallei / Q000276:immunology*; D016957:Burkholderia pseudomallei / Q000276:immunology*; D015200:Fluoroimmunoassay / Q000379:methods*; D005896:Glanders / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008554:Melioidosis / Q000175:diagnosis* / Q000382:microbiology; D015203:Reproducibility of Results
chemical_list: D000942:Antigens, Bacterial