[Clinical analysis of 206 pregnant patients with multiple organ dysfunction syndrome].
OBJECTIVE
To analyze 206 cases of pregnant women with multiple organ dysfunction syndrome (MODS) due to different primary diseases and the prognosis.


METHODS
A retrospective study was conducted of 206 cases of pregnant women with MODS who were treated during January 2000 to December 2006 in the Third Affiliated Hospital of Guangzhou Medical College, regarding their primary disease and prognosis.


RESULTS
Fourty-four cases among the 206 pregnant women with MODS died. The main primary causes were postpartum hemorrhage in 63 cases (30.6%), severe preeclampsia or eclampsia 60 cases (29.1%), pregnancy with hepatitis C in 23 cases (11.2%), pregnancy with heart disease in 11 cases (5.3%), 12 cases of ectopic pregnancy (5.8%). The mortality was mainly because of pregnancy complicated with heart disease (63.6%), ectopic pregnancy (41.7%), pregnancy with hepatitis (22.7%), of postpartum hemorrhage (17.5%) and severe preeclampsia-eclampsia (11.7%). The difference was statistically significant (P < 0.05).


CONCLUSIONS
Primary diseases leading to pregnancy complicated with MODS are mainly due to obstetric factors, accounting for 65.05%. However, dysfunction of different organs can result in a significant difference in mortality, mortality from primary diseases of the heart and brain were higher. It is suggested that preventative and therapeutic measures should be taken according to different primary disease organs.
Chen
Dun-Jin
DJ
Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou, China. chendunjin@hotmail.com
Wang
Xiao-Yi
XY
D000328:Adult; D002423:Cause of Death; D005260:Female; D006801:Humans; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality*; D006473:Postpartum Hemorrhage / Q000401:mortality; D011225:Pre-Eclampsia / Q000401:mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality*; D011249:Pregnancy Complications, Cardiovascular / Q000401:mortality; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate