Metabolic syndrome in females with polycystic ovary syndrome and International Diabetes Federation criteria.
OBJECTIVE
To find out the incidence of metabolic syndrome (MS) in females with polycystic ovary syndrome (PCOS) and to assess the metabolic risk factors as per the definition of International Diabetes Federation.


METHODS
One hundred and seventeen females (39 adolescents and 78 adults) diagnosed with PCOS underwent assessments clinically and by appropriate laboratory tests for the evidence of MS, as per the criteria laid down by International Diabetes Federation.


RESULTS
MS was diagnosed in 54 cases (46.2%), of which 43.6% were adolescents and 47.4% were adults (difference not statistically significant). MS in females with PCOS had significantly higher body mass index compared to those who did not have MS, irrespective of age. Abnormalities in both the lipids were more common than fasting glucose abnormalities.


CONCLUSIONS
MS was found in 46.2% of females with PCOS, with both adolescents and adults being similarly affected. Dyslipidaemia is more common than impaired fasting glucose and finding one risk factor should prompt the clinician to search for other risk factors. All females with PCOS should undergo periodic screening for MS.
Bhattacharya
Sudhindra M
SM
Sri Aurobinda Seva Kendra, Kolkata, India. sudhin@vsnl.net
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001786:Blood Glucose; D001794:Blood Pressure; D015992:Body Mass Index; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D012955:Societies, Medical
D001786:Blood Glucose; D008055:Lipids