title: Prevalence and prognosis of coexistent asymptomatic intracranial stenosis.
abstract: OBJECTIVE
  There are limited data on the prevalence and prognosis of asymptomatic intracranial stenosis (AIS).
  
  
  METHODS
  Baseline cerebral angiograms and MR angiograms were used to determine AIS (50% to 99%) coexistent to symptomatic intracranial stenosis for patients enrolled in the Warfarin-Aspirin Symptomatic Intracranial Disease study.
  
  
  RESULTS
  Coexisting AIS were detected in 18.9% (n=14/74) of patients undergoing 4-vessel cerebral angiography and 27.3% (n=65/238) of patients undergoing MR angiogram. During a mean follow-up period of 1.8 years, no ischemic strokes were attributable to an AIS on cerebral angiography and 5 ischemic strokes (5.9%, 95% CI: 2.1% to 12.3%) occurred in the AIS territory on MR angiogram (risk at 1 year=3.5%, 95% CI: 0.8% to 9.0%).
  
  
  CONCLUSIONS
  Whereas the prevalence of coexisting AIS (50% to 99%) in patients with symptomatic stenosis is high, the risk of stroke from these asymptomatic stenoses is low.
authors.forename: Fadi
authors.initials: F
authors.lastname: Nahab
authors.forename: George
authors.initials: G
authors.lastname: Cotsonis
authors.forename: Michael
authors.initials: M
authors.lastname: Lynn
authors.forename: Edward
authors.initials: E
authors.lastname: Feldmann
authors.forename: Seemant
authors.initials: S
authors.lastname: Chaturvedi
authors.forename: J Claude
authors.initials: JC
authors.lastname: Hemphill
authors.forename: Richard
authors.initials: R
authors.lastname: Zweifler
authors.forename: Karen
authors.initials: K
authors.lastname: Johnston
authors.forename: David
authors.initials: D
authors.lastname: Bonovich
authors.forename: Scott
authors.initials: S
authors.lastname: Kasner
authors.forename: Marc
authors.initials: M
authors.lastname: Chimowitz
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000150:complications / Q000209:etiology; D002533:Cerebral Angiography; D003251:Constriction, Pathologic; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D002537:Intracranial Arteriosclerosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D018810:Magnetic Resonance Angiography; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D018570:Risk Assessment; D020521:Stroke / Q000453:epidemiology / Q000209:etiology