title: [Common variable immunodeficiency: a 7 cases reported].
abstract: BACKGROUND
  Common variable immunodeficiency (CVID) is an immune defect characterized by primary hypogammaglobulinemia. The most clinical manifestations are recurrent infection of respiratory tract.
  
  
  OBJECTIVE
  We reported seven cases of DICV which showed
  
  
  METHODS
  We reported seven cases of CVID between 1994 and 2004, included six women and one man.
  
  
  RESULTS
  The mean age at the first clinical symptoms is 23 years and the mean age at diagnosis is 38. Six patients presented recurrent bacterial infection particularly of the upper and the lower respiratory tract, these infections can lead to chronic diseases such as bronchiectasis. Two patients had chronic diarrhea caused by nodular lymphoid hyperplasia, we showed two cases of granulomatous: spleen tuberculosis and pulmonary sarcoidosis. The diagnostic was confirmed by protein electrophoresis and serum levels of immunoglobulin. All patients received treatment with intravenous immunoglobulin, with a decrease in frequency and severity of infection episodes.
  
  
  CONCLUSIONS
  Protein electrophoresis must be done in a young adult with recurrent low respiratory tract infections and/or diffuse bronchectasis.
authors.affiliation: Service de Pneumologie, centre hospitalo-universitaire Farhat Hached de Sousse, Tunisie.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Abdelghani
authors.forename: Mabrouk
authors.initials: M
authors.lastname: Khalifa
authors.forename: Sonia
authors.initials: S
authors.lastname: Mezghani
authors.forename: Abdelaziz
authors.initials: A
authors.lastname: Hayouni
authors.forename: Fethi
authors.initials: F
authors.lastname: Bahri
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Garrouche
authors.forename: Néji
authors.initials: N
authors.lastname: Klabi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Benzarti
authors.forename: Mohamed
authors.initials: M
authors.lastname: Jerray
mesh_terms: D000328:Adult; D017074:Common Variable Immunodeficiency / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies