title: Early radiation effects on tongue function for patients with nasopharyngeal carcinoma: a preliminary study.
abstract: The purpose of this study was to investigate early radiation effects on tongue function for patients with nasopharyngeal carcinoma (NPC) and to provide a scientific database for early intervention plans. Twelve subjects with NPC and 12 age- and sex-matched normal subjects were included. Tongue maximum isometric strength and endurance at 50% of maximum strength were obtained once from normal subjects with the Iowa Oral Performance Instrument (IOPI) and twice from the NPC subjects: before and 2 months after radiation treatment. No significant differences were found in tongue function evaluation for normal or NPC groups in either pre- or post-treatments. However, this study showed that significant decreases in tongue function may not start until 2 months after treatment.
authors.affiliation: Department of Otolaryngology, Speech and Hearing Center, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chin-Wen
authors.initials: CW
authors.lastname: Chang
authors.forename: Sheng Hwa
authors.initials: SH
authors.lastname: Chen
authors.forename: Jenq-Yuh
authors.initials: JY
authors.lastname: Ko
authors.forename: Yang-Hua
authors.initials: YH
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000532:radiotherapy*; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D009367:Neoplasm Staging; D010609:Pharyngeal Muscles / Q000503:physiopathology / Q000528:radiation effects; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors