[Quantitative electroencephalogram analysis confirms the presence of frontal lobe deficit among attention deficit disorder with hyperactivity children].
BACKGROUND
[corrected] The Attention Deficit Disorder with Hyperactivity (ADDH) Barkley model predicts concomitant deficits in working memory and in the development of a sense of time as a consequence of poor behavioral inhibition.


OBJECTIVE
To evaluate electrophysiologically Barkley's theory (1997).


METHODS
We studied the electroencephalogram (EEG) of fifteen right-handed, normal limit IQ ADDH children (inattentive subtype), aged 7-11 years, and a control group. Subjects were studied at rest, with the eyes open (RO) while performing a time estimation task (ET). Forty-two data matrices were analyzed in three conditions: RO, ET and ET-RO, to assess broad-band spectral parameters; the anteriority, temporal-referenced and laterality quotients (Aq, Aqt and Lq, respectively); and the theta/alpha and theta/beta ratios.


RESULTS
Analyses of variance revealed significant differences for ES-RA, in absolute (Aq &Aqt) and relative powers (Aq). Discriminant function analysis was able to predict group membership with an accuracy over 80%, but it decreased slightly when the leave-one-out method was applied Linear discrimination based on right hemisphere Aqt values showed the highest discrimination accuracy.


CONCLUSIONS
These results support Barkley's theory, suggesting further evaluation of the temporal-referenced anteriority quotient as a promising electrophysiological tool for the diagnosis and follow up of ADDH children.
Madera-Carrillo
Humberto
H
Instituto de Neurociencias, Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Guadalajara, Jal., México. hmadera@cucba.udg.mx
González-Garrido
Andrés Antonio
AA
Gómez-Velázquez
Fabiola R
FR
Enríquez-de Rivera
Daniel Zarabozo
DZ
D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis* / Q000503:physiopathology*; D002648:Child; D004569:Electroencephalography / Q000379:methods*; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans