title: Drugs and fatal traffic accidents in the Czech Republic.
abstract: BACKGROUND
  The aim of the study was to determine the prevalence of psychotropic drug use in active participants in traffic accidents who died during the accident or shortly after it due to injuries resulting from the accident.
  
  
  METHODS
  A special mortality register containing data of all forensic autopsies was analysed. The studied sample consisted of persons who died during traffic accidents and were active participants in those ones (pedestrians, cyclists, or drivers), and were toxicologically tested during the forensic examination.
  
  
  RESULTS
  The sample consisted of 1,213 cases, 1,039 (85.7%) males and 174 (14.3%) females who died in 2003-2005. Ethanol was found in 34.7% of cases, however a significant declining trend over the years was noted. The proportion of positive detections for any psychotropic drug other than alcohol was 7.2%; benzodiazepines were found most frequently (3.6%), followed by cannabis (2.2%), and stimulants (1.7% of the sample). Positive findings of ethanol were significantly more common among males, whereas positive benzodiazepine tests were more frequent in females. Positive cases were significantly younger than negative ones for ethanol, volatile substances, stimulants, and cannabis; in cases of positive medicaments tests, the positive cases were significantly older than the negatives.
authors.affiliation: Czech National Monitoring Centre for Drugs and Drug Addiction, Prague, Czech Republic. mravcik.viktor@vlada.cz
authors.forename: Viktor
authors.initials: V
authors.lastname: Mravcík
authors.forename: Frantisek
authors.initials: F
authors.lastname: Vorel
authors.forename: Tomás
authors.initials: T
authors.lastname: Zábranský
mesh_terms: D000063:Accidents, Traffic / Q000401:mortality* / Q000706:statistics & numerical data; D000328:Adult; D000435:Alcoholic Intoxication / Q000150:complications / Q000453:epidemiology*; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D005554:Forensic Medicine / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D018986:Motor Vehicles; D011619:Psychotropic Drugs; D012042:Registries; D012189:Retrospective Studies; D015813:Substance Abuse Detection; D019966:Substance-Related Disorders / Q000150:complications / Q000453:epidemiology*
chemical_list: D011619:Psychotropic Drugs