title: Glomus tumor and glomangioma of the nerve. Report of two cases.
abstract: As a rule, normal human nerve does not contain glomus bodies. Nonetheless, rare examples of glomus tumors do arise in peripheral nerves of various sizes. Their pathobiological characteristics are poorly understood, but reported examples have been small and clinically benign. The authors identified in 1 patient each a glomus tumor and a glomangioma involving nerve. Clinical histories as well as imaging and surgical findings were reviewed. All available H & E-stained slides were examined in both cases. Immunohistochemical stains and electron microscopy, as appropriate, were also performed. The lesions were subtotally and completely resected, respectively. An uneventful postoperative recovery was noted in both patients. Glomus tumors and glomangiomas can involve major nerves on rare occasions. They seem to follow a favorable clinical course, and conservative resection can be of benefit.
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA. scheithauer.bernd@mayo.edu
authors.forename: Bernd W
authors.initials: BW
authors.lastname: Scheithauer
authors.forename: Fausto J
authors.initials: FJ
authors.lastname: Rodriguez
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Spinner
authors.forename: P James
authors.initials: PJ
authors.lastname: Dyck
authors.forename: Ayman
authors.initials: A
authors.lastname: Salem
authors.forename: Fredric L
authors.initials: FL
authors.lastname: Edelman
authors.forename: Kimberly K
authors.initials: KK
authors.lastname: Amrami
authors.forename: Yao-Shi
authors.initials: YS
authors.lastname: Fu
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D005918:Glomus Tumor / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D020423:Median Neuropathy / Q000175:diagnosis* / Q000473:pathology; D009408:Nerve Compression Syndromes / Q000175:diagnosis; D009442:Neurilemmoma / Q000175:diagnosis; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology; D020426:Sciatic Neuropathy / Q000175:diagnosis* / Q000473:pathology