Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects.
Murkin
Andrew S
AS
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA.
Tyler
Peter C
PC
Schramm
Vern L
VL
D001667:Binding, Competitive; D006801:Humans; D007288:Inosine / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D011684:Purine Nucleosides / Q000737:chemistry / Q000378:metabolism; D011683:Purine-Nucleoside Phosphorylase / Q000737:chemistry* / Q000378:metabolism*; D011744:Pyrimidinones / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics; D014316:Tritium
D011684:Purine Nucleosides; D011744:Pyrimidinones; D014316:Tritium; C113101:forodesine; D007288:Inosine; D011683:Purine-Nucleoside Phosphorylase