Possible mechanisms for the regulation of neutrophil apoptosis during allergic inflammation.
The neutrophil-mediated inflammatory response is regulated via activation of the apoptosis program, which decreases the degree of tissue alteration. In rabbits with allergic inflammation a significant negative correlation was revealed between the intensity of neutrophil apoptosis and blood interferon-gamma concentration.
Moiseeva
E G
EG
Department of General Pathology and Pathophysiology, Russian Peoples' Friendship University of Russia, Moscow.
Pasechnik
A V
AV
Drozdova
G A
GA
Frolov
V A
VA
D000818:Animals; D017209:Apoptosis / Q000276:immunology*; D006967:Hypersensitivity / Q000276:immunology* / Q000473:pathology*; D007249:Inflammation / Q000276:immunology* / Q000473:pathology*; D007371:Interferon-gamma / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D017737:Macrophages, Peritoneal / Q000276:immunology; D008297:Male; D009504:Neutrophils / Q000276:immunology* / Q000473:pathology*; D010587:Phagocytosis; D011817:Rabbits
D015847:Interleukin-4; D007371:Interferon-gamma