Synthesis of C3-symmetric and C4-symmetric amino acid derivatives via Suzuki-Miyaura cross-coupling reaction.
Various non-natural C(3)- and C(4)-symmetric alpha-amino acid derivatives have been synthesized via Suzuki-Miyaura cross-coupling reaction between aromatic iodides or bromide and a suitably protected DL-4-boronophenylalanine derivative.
Kotha
S
S
Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai, India. srk@chem.iitb.ac.in
Shah
V R
VR
D024322:Amino Acids, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry
D024322:Amino Acids, Aromatic