title: [Surface pretreatment of endoprostheses by silica/silane to optimise the hydrolytic stability between bone cement and metal. Total hip and knee arthroplasty].
abstract: BACKGROUND
  The aseptic loosening of cemented total hip and knee arthroplasties is still an unsolved problem. In this regard, the hydrolytic resistance in the metal-to-bone cement interface is of major importance.
  
  
  METHODS
  Cemented pretreated femur stems and tibia components coated by means of a silica/silane interlayer system were dynamically loaded with the help of a hip and knee simulator similar to DIN ISO Norm. After loading, the components were microscopically analysed concerning both debonding in the metal-to-bone cement interface and cement mantle defects. These data were matched with uncoated components. Unloaded coated and uncoated femur and tibia components acted as controls.
  
  
  RESULTS
  Compared with uncoated components, the pretreated and coated ones yielded a significant reduction in cement defects as well as of debonding in the metal-to-bone cement interface.
  
  
  CONCLUSIONS
  Using the silica/silane interlayer system for cemented femur and tibia components, hydrolytic debonding in the metal-to-bone cement interface with following cement mantle failure can be reduced. This could help increase the long-term stability of the metal-to-bone cement compound, with decreased aseptic loosening.
authors.affiliation: Orthopädische Klinik, Universitätsklinikum, Pauwelsstrasse 30, 52074, Aachen, Germany. torsten.mumme@gmx.de
authors.forename: T
authors.initials: T
authors.lastname: Mumme
authors.forename: R
authors.initials: R
authors.lastname: Marx
authors.forename: R
authors.initials: R
authors.lastname: Müller-Rath
authors.forename: S
authors.initials: S
authors.lastname: Gravius
authors.forename: S
authors.initials: S
authors.lastname: Andereya
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
mesh_terms: D001696:Biomechanical Phenomena; D020099:Coated Materials, Biocompatible; D017076:Computer-Aided Design; D019544:Equipment Failure Analysis; D006622:Hip Prosthesis; D006801:Humans; D007720:Knee Prosthesis; D019904:Polymethyl Methacrylate; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012821:Silanes; D012822:Silicon Dioxide; D013499:Surface Properties; D016474:Weight-Bearing
chemical_list: D020099:Coated Materials, Biocompatible; D012821:Silanes; D012822:Silicon Dioxide; D019904:Polymethyl Methacrylate