Diene-titanium complexes as synthetic intermediates for the construction of three- or five-membered carbocycles.
It has been shown that diene-titanium complexes exhibit substrate-dependent 1,2- or 1,4-dicarbanion reactivity. On this basis, 3-cyclopentenylamines and spiro-vinylcyclopropane lactams were easily prepared by using homoallylic Grignard reagents, Ti(O-i-Pr)4, and nitriles or cyanoesters, respectively.
Bertus
Philippe
P
ICMR - UMR 6229, CNRS - Université de Reims Champagne-Ardenne, BP 1039, 51687 Reims Cedex 2, France. philippe.bertus@univ-lemans.fr
Menant
Christine
C
Tanguy
Chloé
C
Szymoniak
Jan
J