Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation.
Jamal
R
R
Bélisle
C
C
Lessard
M-C
MC
Hébert
J
J
Roy
D-C
DC
Levine
R
R
Busque
L
L
D006410:Hematopoiesis; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D053614:Janus Kinase 2 / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009154:Mutation; D012008:Recurrence; D018183:Transplantation Chimera; D014184:Transplantation, Homologous
C507924:JAK2 protein, human; D053614:Janus Kinase 2; D006918:Hydroxyurea