Behçet's disease complicated by IgA nephropathy with nephrotic syndrome.
A 65-year-old woman with a 48-year history of Behçet's disease associated with nephrotic syndrome is described. Immunofluorescence study revealed IgA nephropathy. Following treatment with an angiotensin II type-I receptor-blocker, an anti-platelet drug, and an HMG-CoA reductase inhibitor, accompanied by dietary restrictions of protein and sodium, proteinuria was markedly decreased. This report describes our experience with a rare entity of Behçet's disease complicated by nephrotic syndrome due to IgA nephropathy. Routine urine examination and renal biopsy are needed for the detection and diagnosis of renal problems with Behçet's disease.
Hashimoto
Tatsuo
T
Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, Kanazawa-ku, Yokohama 236-0004, Japan. tatsuo_h@med.yokohama-cu.ac.jp
Toya
Yoshiyuki
Y
Kihara
Minoru
M
Yabana
Machiko
M
Inayama
Yoshiaki
Y
Tanaka
Ken-Ichiro
K
Iwatsubo
Kousaku
K
Yanagi
Mai
M
Oshikawa
Jin
J
Kokuho
Toshiharu
T
Kuji
Tadashi
T
Yoshida
Shin-Ichiro
S
Tamura
Kouichi
K
Umemura
Satoshi
S
D000368:Aged; D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D000069059:Atorvastatin; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D001562:Benzimidazoles / Q000627:therapeutic use; D001713:Biphenyl Compounds / Q000627:therapeutic use; D004109:Dilazep / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications*; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D009404:Nephrotic Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000209:etiology; D011758:Pyrroles / Q000627:therapeutic use; D013777:Tetrazoles / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
D047228:Angiotensin II Type 1 Receptor Blockers; D001562:Benzimidazoles; D001713:Biphenyl Compounds; D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011758:Pyrroles; D013777:Tetrazoles; D014665:Vasodilator Agents; D000069059:Atorvastatin; D004109:Dilazep; C077793:candesartan cilexetil