Contribution of spinal MRI for unsuspected cobalamin deficiency in isolated sub-acute combined degeneration.
Sub-acute combined degeneration (SCD) is a rare cause of demyelination of the dorsal and lateral columns of the spinal cord and is a neurological complication due to vitamin B12 deficiency. Revealing forms of SCD without anemia are rare. We report a case of SCD of the spinal cord in a 33-year-old woman without anemia but with a 10-month history of paresthesis and urine imperiosity. Magnetic resonance imaging (MRI) of the spine showed intramedullary hyperintensity seen on T2-weighted images in the posterior column of the cervico-dorsal spinal cord, extending from C1 to D1. A diagnosis of SCD of the spinal cord was considered and confirmed by a low serum cobalamin. The patient was treated with vitamin B12 supplements and showed gradual improvement in her clinical symptoms.
Maamar
M
M
Department of Internal Medicine, Ibn Sina hospital, Rabat, Morocco.
Mezalek
Z Tazi
ZT
Harmouche
H
H
Adnaoui
M
M
Aouni
M
M
Maaouni
A
A
D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D052879:Subacute Combined Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D014805:Vitamin B 12 / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000150:complications / Q000188:drug therapy
D014805:Vitamin B 12