title: [Periodic fever--two children with periodic fever, aphthous stomatitis pharyngitis, adenitis syndrome].
abstract: PFAPA (periodic fever, aphthous stomatitis, pharyngitis, adenitis) syndrome is characterised by episodes of fever (>40 degrees C), lasting 4-5 days and recurring every 3-6 weeks, accompanied by aphthous stomatitis, pharyngitis or cervical adenitis. Between the episodes of fever there are no symptoms. Glucocorticoids are highly effective in controlling the symptoms, while tonsillectomy results in remission. We describe two children with PFAPA syndrome. Early diagnosis can significantly improve the patients' quality of life.
authors.affiliation: Sygehus Vendsyssel Hjørring, Paediatrisk Afdeling. torbenmikkelsen2003@yahoo.dk
authors.forename: Torben Stamm
authors.initials: TS
authors.lastname: Mikkelsen
authors.forename: Karen A
authors.initials: KA
authors.lastname: Tilma
mesh_terms: D005334:Fever / Q000175:diagnosis / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008199:Lymphadenitis / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D010507:Periodicity; D010612:Pharyngitis / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013281:Stomatitis, Aphthous / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013577:Syndrome; D014068:Tonsillectomy
chemical_list: D005938:Glucocorticoids