Progressive ataxia in a captive North American river otter (Lontra canadensis) associated with brain stem spheroid formation.
Progressive ataxia, particularly of the hind limbs, developed in a paretic female juvenile captive North American river otter (Lontra canadensis). Severe bilaterally symmetrical axonal degeneration in the medulla oblongata (nucleus gracilis and nucleus cuneatus) and multiple scattered spheroids in the region of the pons were detected microscopically. This is the first description of ataxia associated with axonal degeneration in otters.
Schettler
Elvira
E
Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke Strasse 17, D-10315 Berlin, Germany.
Müller
Kerstin
K
Fritsch
Guido
G
Kaiser
Stefan
S
Brunnberg
Leo
L
Frölich
Kai
K
Wibbelt
Gudrun
G
D000818:Animals; D000836:Animals, Zoo; D001259:Ataxia / Q000209:etiology / Q000662:veterinary*; D001921:Brain / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D010041:Otters; D018874:Spheroids, Cellular