Application of glycosyl thioimidates in solid-phase oligosaccharide synthesis.
Two stable classes of thioimidoyl derivatives, S-benzoxazolyl (SBox) and S-thiazolinyl (STaz) glycosides, were investigated as glycosyl donors for solid-phase oligosaccharide synthesis. It was demonstrated that these derivatives are suitable for both glycosyl acceptor-bound and glycosyl donor-bound strategies, commonly employed in resin-supported oligosaccharide synthesis.
Parlato
M Cristina
MC
Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
Kamat
Medha N
MN
Wang
Haisheng
H
Stine
Keith J
KJ
Demchenko
Alexei V
AV
D007094:Imides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009844:Oligosaccharides / Q000138:chemical synthesis*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D007094:Imides; D009844:Oligosaccharides; D013438:Sulfhydryl Compounds