[Tertiary peritonitis: aspects of prophylaxis].
Thirteen patients with generalized purulent peritonitis were treated with multiple staging sanation of abdominal cavity and special bacteriophages with high activity to 4 nosocomial bacterium strains. The phages permitted to prevent infection with these nosocomial strains. Three new phages with high bacteriolytic activity were identified. Antibacterial activity "in vitro" of all phages was higher than antibiotic susceptibility. It is concluded that bacteriophages are promising method of treatment and prevention of complications associated with nosocomial infection at surgical patients with long-time purulent processes.
Gostishchev
V K
VK
Stanoevich
U S
US
Aleshkin
V A
VA
Afanas'ev
S S
SS
Voropaeva
E A
EA
Shkrob
L O
LO
Matvievskaia
N S
NS
Popov
D V
DV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000378:metabolism; D001435:Bacteriophages / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D012680:Sensitivity and Specificity
D000890:Anti-Infective Agents