[Fluorescence endoscopy of the respiratory tract].
Autofluorescence endoscopy has been used for more than 10 years in the diagnosis of early lung cancers and precancerous lesions of the bronchial tree. The technique has been extensively evaluated during the past decade and two recent large randomised studies have shown a 2 to 5 times increase in the detection of high grade pre-cancerous lesions compared with conventional white light endoscopy. This paper reviews the principal applications and results of the use of autofluorescence endoscopy in high risk individuals as well as innovative endoscopic approaches using the fluorescent properties of the respiratory tract.
Thiberville
L
L
Clinique Pneumologique, Hôpital Charles-Nicolle, Centre Hospitalier et Universitaire de Rouen, Rouen cedex, France. luc.thiberville@univ-rouen.fr
Salaün
M
M
Lachkar
S
S
D001984:Bronchial Neoplasms / Q000473:pathology*; D004724:Endoscopy / Q000379:methods; D005453:Fluorescence; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology