title: Central nervous system relapse occurs in about 5% of cases of acute promyelocytic leukaemia.
abstract: In this report, we present images from a patient with acute promyelocytic leukemia who experienced several central nervous system relapses.
authors.affiliation: Divisione di Ematologia, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy. castagnola@smatteo.pv.it
authors.forename: Carlo
authors.initials: C
authors.lastname: Castagnola
authors.forename: Chiara
authors.initials: C
authors.lastname: Elena
authors.forename: Michele
authors.initials: M
authors.lastname: Merli
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D002467:Cell Nucleus / Q000473:pathology*; D016543:Central Nervous System Neoplasms / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D015255:Idarubicin; D015473:Leukemia, Promyelocytic, Acute / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D015514:Oncogene Proteins, Fusion / Q000134:cerebrospinal fluid / Q000235:genetics; D012334:RNA, Neoplasm / Q000134:cerebrospinal fluid / Q000235:genetics; D012008:Recurrence; D012074:Remission Induction; D014212:Tretinoin
chemical_list: D015514:Oncogene Proteins, Fusion; D012334:RNA, Neoplasm; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein; D014212:Tretinoin; D015255:Idarubicin