Central nervous system relapse occurs in about 5% of cases of acute promyelocytic leukaemia.
In this report, we present images from a patient with acute promyelocytic leukemia who experienced several central nervous system relapses.
Castagnola
Carlo
C
Divisione di Ematologia, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy. castagnola@smatteo.pv.it
Elena
Chiara
C
Merli
Michele
M
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D002467:Cell Nucleus / Q000473:pathology*; D016543:Central Nervous System Neoplasms / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D015255:Idarubicin; D015473:Leukemia, Promyelocytic, Acute / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D015514:Oncogene Proteins, Fusion / Q000134:cerebrospinal fluid / Q000235:genetics; D012334:RNA, Neoplasm / Q000134:cerebrospinal fluid / Q000235:genetics; D012008:Recurrence; D012074:Remission Induction; D014212:Tretinoin
D015514:Oncogene Proteins, Fusion; D012334:RNA, Neoplasm; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein; D014212:Tretinoin; D015255:Idarubicin