title: Photorefractive keratectomy for refractory laser in situ keratomileusis flap striae.
abstract: Photorefractive keratectomy (PRK) with mitomycin-C (MMC) was performed in 2 patients with visually significant, complicated laser in situ keratomileusis flap striae. These striae had been resistant to multiple treatments, including stretching, suturing, and PRK. The visual symptoms in both patients resolved after PRK with MMC, and both patients were stable 1 year later. Wavefront-guided PRK with MMC may be a viable treatment for patients who have complicated flap striae resistant to standard measures.
authors.affiliation: Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21236, USA. ickuo@jhmi.edu
authors.forename: Irene C
authors.initials: IC
authors.lastname: Kuo
authors.forename: Nada S
authors.initials: NS
authors.lastname: Jabbur
authors.forename: Terrence P
authors.initials: TP
authors.lastname: O'Brien
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003316:Corneal Diseases / Q000209:etiology / Q000601:surgery*; D003319:Corneal Stroma / Q000473:pathology / Q000601:surgery*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D018903:Photorefractive Keratectomy; D013524:Surgical Flaps; D014792:Visual Acuity
chemical_list: D016685:Mitomycin