title: Rapid in vivo musculoskeletal MR with parallel imaging at 7T.
abstract: The purpose of this work was to implement autocalibrating GRAPPA-based parallel imaging (PI) for in vivo high-resolution (HR) MRI of cartilage and trabecular bone micro-architecture at 7T and to evaluate its performance based on comparison of MR-derived morphology metrics between accelerated and conventional images and comparison of geometry factor measures between 3T and 7T. Using an eight channel coil array for trabecular MRI at the ankle, a higher maximum feasible acceleration (R) = 6 and lower geometry factor values than that at 3T were observed. The advantages of two-dimensional acceleration were also demonstrated. In knee cartilage and bone acquisitions, feasibility of PI with a dual-channel quadrature coil was investigated. Robust quantification of bone and cartilage metrics could be derived from accelerated ankle and knee acquisitions. PI can enhance the clinical feasibility of in vivo bone and cartilage HR-MRI for osteoporosis and osteoarthritis at 7T.
authors.affiliation: Radiology, University of California, San Francisco, San Francisco, California 94158, USA. suchandrima.banerjee@radiology.ucsf.edu
authors.forename: Suchandrima
authors.initials: S
authors.lastname: Banerjee
authors.forename: Roland
authors.initials: R
authors.lastname: Krug
authors.forename: Julio
authors.initials: J
authors.lastname: Carballido-Gamio
authors.forename: Douglas A C
authors.initials: DA
authors.lastname: Kelley
authors.forename: Duan
authors.initials: D
authors.lastname: Xu
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Vigneron
authors.forename: Sharmila
authors.initials: S
authors.lastname: Majumdar
mesh_terms: D000843:Ankle Joint / Q000033:anatomy & histology*; D016477:Artifacts; D001842:Bone and Bones / Q000033:anatomy & histology; D002358:Cartilage, Articular / Q000033:anatomy & histology; D005240:Feasibility Studies; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D007719:Knee Joint / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D009141:Musculoskeletal System / Q000033:anatomy & histology*