Studying autophagy's relationship to cell death.
Depending on the circumstances, autophagy can prevent, cause or regulate the kinetics of cell death. Consequently, it is particularly important that experimental strategies to study these responses are designed carefully. Here, I discuss some of the issues to be considered when designing such experiments.
Thorburn
Andrew
A
Department of Pharmacology, University of Colorado, Denver, School of Medicine, Aurora, Colorado, USA. Andrew.Thorburn@uchsc.edu
D000818:Animals; D001343:Autophagy / Q000502:physiology*; D016923:Cell Death / Q000502:physiology; D006801:Humans