title: Intraocular lens staining associated with Prosed/DS.
abstract: A 59-year-old pseudophakic woman with a history of Prosed/DS use demonstrated a discolored Tecnis Z9001 (AMO) silicone intraocular lens (IOL). Polymethyl methacrylate (PMMA), hydrophobic acrylic, silicone, and Collamer IOLs were submerged in a physiologic concentration of methylene blue at 35 degrees C for 8 weeks and evaluated. No staining was noted in PMMA or hydrophobic acrylic IOLs, variable staining was noted in silicone IOLs, and intense staining was noted in Collamer IOLs. This is the first report of IOL staining with systemic use of methylene blue and of Collamer lens staining characteristics.
authors.affiliation: Commonwealth Eye Surgery, Lexington, Kentucky 40504, USA. lferguson@commonwealtheyes.com
authors.forename: Lance S
authors.initials: LS
authors.lastname: Ferguson
mesh_terms: D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects*; D003556:Cystitis / Q000188:drug therapy; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008751:Methylene Blue / Q000009:adverse effects*; D008875:Middle Aged; D018918:Phacoemulsification; D017797:Prosthesis Coloring; D011475:Prosthesis Failure; D012826:Silicone Elastomers
chemical_list: D000892:Anti-Infective Agents, Urinary; D012826:Silicone Elastomers; D008751:Methylene Blue