Stabilizing effect of Silene pectin polysaccharide on electrical activity of the sinoatrial area in frog heart.
Silenan, a pectin polysaccharide from common catchfly (Silene vulgaris), corrects disorders in the conduction of action potentials between cells of the sinoatrial area of frog heart forming a functional syncytium. Recovery of action potential conduction in the sinoatrial cells was recorded in long-term experiments (>8 h). The effect of silenan manifested mainly against the background of arrhythmic generation and impaired propagation of action potentials.
Golovko
V A
VA
Institute of Physiology, Komi Research Center, the Ural Branch of Russian Academy of Sciences, Syktyvkar. golovko@physiol.komisc.ru
Bushneva
O A
OA
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002240:Carbohydrate Sequence; D004594:Electrophysiology; D066298:In Vitro Techniques; D008969:Molecular Sequence Data; D009200:Myocardial Contraction / Q000187:drug effects; D010368:Pectins / Q000737:chemistry / Q000494:pharmacology*; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology*; D011896:Rana temporaria / Q000502:physiology*; D029751:Silene / Q000737:chemistry; D012849:Sinoatrial Node / Q000187:drug effects* / Q000502:physiology*
D011134:Polysaccharides; D010368:Pectins; C491985:silenan