Parietal activation during retrieval of abstract and concrete auditory information.
Successful memory retrieval has been associated with a neural circuit that involves prefrontal, precuneus, and posterior parietal regions. Specifically, these regions are active during recognition memory tests when items correctly identified as "old" are compared with items correctly identified as "new." Yet, as nearly all previous fMRI studies have used visual stimuli, it is unclear whether activations in posterior regions are specifically associated with memory retrieval or if they reflect visuospatial processing. We focus on the status of parietal activations during recognition performance by testing memory for abstract and concrete nouns presented in the auditory modality with eyes closed. Successful retrieval of both concrete and abstract words was associated with increased activation in left inferior parietal regions (BA 40), similar to those observed with visual stimuli. These results demonstrate that activations in the posterior parietal cortex during retrieval cannot be attributed to bottom-up visuospatial processes but instead have a more direct relationship to memory retrieval processes.
Klostermann
Ellen C
EC
Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA. Electronic address: eklostermann@berkeley.edu.
Kane
Ari J M
AJM
Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
Shimamura
Arthur P
AP
Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*