5-Phenyluridine trihydrate.
In the title compound, C(15)H(16)N(2)O(6).approximately 3H(2)O, the substituted uracil ring is oriented in the anti position relative to the ribose ring, and the phenyl and uracil rings are oriented in a noncoplanar fashion. The furanose ring adopts a conformation close to 3'-endo, in contrast to the furanose conformation seen in the crystal structure of the synthetic precursor 5-bromouridine, which is close to 2'-endo. The molecule is involved in an extensive hydrogen-bonding network with several water molecules, some of which are disordered.
Pesnot
Thomas
T
School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich NR4 7TJ, England.
Hughes
David L
DL
Wagner
Gerd K
GK
D018360:Crystallography, X-Ray; D015394:Molecular Structure; D014529:Uridine / Q000031:analogs & derivatives* / Q000737:chemistry*
C527809:5-phenyluridine; D014529:Uridine