Phenome connections.
Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct, suggesting that they share a genetic basis. Their results imply that the human phenome can be viewed as a landscape of interrelated diseases, reflecting overlapping molecular causation.
Oti
Martin
M
Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.
Huynen
Martijn A
MA
Brunner
Han G
HG
D030342:Genetic Diseases, Inborn / Q000235:genetics; D005820:Genetic Testing; D014644:Genetic Variation; D023281:Genomics; D005838:Genotype; D006801:Humans; D010641:Phenotype