title: Fine-needle aspiration biopsy of disseminated sporotrichosis: a case report.
abstract: In this report, we describe a case of disseminated sporotrichosis that was diagnosed by fine-needle aspiration biopsy (FNAB). The cytologic smears exhibited a large number of macrophages, few polymorphonuclear neutrophils and numerous round or oval, sometimes elongated, isolated and scattered yeast-like structures localized extracellularly or inside macrophages. These structures were clearly visualized by Giemsa and Papanicolaou methods. Cultures from skin biopsy material revealed fungal colonies which were subsequently identified as Sporothrix schenckii. The cytologic aspects, the correlation with histologic findings and the differential cytologic diagnosis were reviewed.
authors.affiliation: Department of Pathology, Hospital das Clínicas, University of São Paulo, São Paulo, Brazil. regerhard@terra.com.br
authors.forename: Renê
authors.initials: R
authors.lastname: Gerhard
authors.forename: Patrícia Carrasco
authors.initials: PC
authors.lastname: de Moscoso
authors.forename: Tatiana Villas Boas
authors.initials: TV
authors.lastname: Gabbi
authors.forename: Neusa Yuriko Sakai
authors.initials: NY
authors.lastname: Valente
mesh_terms: D017088:AIDS-Related Opportunistic Infections; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013175:Sporothrix / Q000302:isolation & purification*; D013174:Sporotrichosis / Q000175:diagnosis* / Q000188:drug therapy; D013194:Staining and Labeling
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B