Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.
Pallan
Pradeep S
PS
Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
Ittig
Damian
D
Héroux
Annie
A
Wawrzak
Zdzislaw
Z
Leumann
Christian J
CJ
Egli
Martin
M
D003460:Crystallization; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D015032:Zinc / Q000737:chemistry
D004247:DNA; D015032:Zinc