title: [Elective single embryo transfer (eSET)--the way to decrease the risk for multiple pregnancy].
abstract: OBJECTIVE
  To present an overview of trials and discussion focused on the method of single embryo transfer leading to reduction of multiple pregnancy rate.
  
  
  METHODS
  Review article.
  
  
  METHODS
  Centre of Assisted Reproduction SANUS, Hradec Králové.
  
  
  METHODS
  Transfer of two embryos after IVF results in high multiple birth (25%) associated with increased morbidity for mother and children. Results of randomized controlled trials show that SET offers live birth rate approximately 35% with minimizing the risk of twins. The trials suggest to perform SET in a group of young women (< or = 36 years old), in the first or second cycle and only with sufficient number of good quality embryos.
  
  
  CONCLUSIONS
  Data demonstrates that a single embryo transfer strategy, currently including one fresh single embryo transfer and one addition frozen-thawed SET, results in a live birth rate comparable with double embryo transfer and significantly reduces multiple birth rate.
authors.affiliation: Centrum asistované reprodukce SANUS, Hradec Králové. rstreda@seznam.cz
authors.forename: Robert
authors.initials: R
authors.lastname: Streda
mesh_terms: D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011272:Pregnancy, Multiple