Degradation kinetics of butylmethoxydibenzoylmethane (avobenzone) in aqueous solution.
The degradation kinetics of avobenzone in aqueous solution was studied at 60 +/- 0.2 degrees C over a pH range of 2.0-10.0. The degradation rates were determined by high performance liquid chromatography. The reaction is found to follow first-order kinetics and the rate constant for the decomposition at 25 degrees C is estimated by extrapolation. The breakdown of avobenzone is shown to be hydroxide ion catalyzed and the Arrhenius plots showed the temperature dependence of avobenzone degradation.
Mbah
C J
CJ
DMI Inc., Wharton, NJ USA.
D000465:Algorithms; D002021:Buffers; D047188:Chalcones / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D019999:Pharmaceutical Solutions; D011427:Propiophenones; D013696:Temperature; D014867:Water
D002021:Buffers; D047188:Chalcones; D019999:Pharmaceutical Solutions; D011427:Propiophenones; D014867:Water; C049935:avobenzone