title: Preoperative embolization of the splenic artery in patients that underwent splenectomy for immune thrombocytopenic purpura.
abstract: Transfusion of platelets, red blood cells, or both is usually necessary immediately after splenic artery ligature in patients with immune thrombocytopenic purpura who undergo splenectomy.
  
  
  OBJECTIVE
  To investigate whether preoperative embolization of the splenic artery reduced the need for transfusion of platelets, red blood cells, or both.
  
  
  METHODS
  Twenty- seven consecutive patients that underwent splenectomy for purpura between October 1999 and March 2006 performed by the same surgical team were enrolled. The first 17 patients did not undergo embolization and were compared with the next 10 patients, who composed the embolization group.
  
  
  RESULTS
  The platelet count in the embolization group rose from a mean 7000 u/microl before to 75000 u/microl after the procedure. There was no need for platelet or red blood cell transfusion in the embolization group; in the group without preoperative embolization, 11 patients (p=0.001) required platelet transfusion and 8 (p=0.01), red blood cell transfusion.
  
  
  CONCLUSIONS
  Embolization of the splenic artery before splenectomy is a safe method to avoid blood transfusions in patients with ITP.
authors.affiliation: Department of Surgery, PUCRS, São Paulo, Brazil. pliniobau@via-rs.net
authors.forename: Plínio Carlos
authors.initials: PC
authors.lastname: Baú
authors.forename: Sílvio Adriano
authors.initials: SA
authors.lastname: Cavazolla
authors.forename: Hamilton Petry
authors.initials: HP
authors.lastname: Souza
authors.forename: Bernardo
authors.initials: B
authors.lastname: Garicochea
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D015331:Cohort Studies; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D017713:Platelet Transfusion; D011300:Preoperative Care; D011696:Purpura, Thrombocytopenic / Q000601:surgery / Q000628:therapy*; D013156:Splenectomy; D013157:Splenic Artery; D055815:Young Adult