title: Novel isocyanide-based three-component synthesis of 3,4-dihydroquinoxalin-2-amine derivatives.
abstract: Synthesis of a novel class of highly substituted 3,4-dihydroquinoxalin-2-amine derivatives including spirocyclic compounds from three-component condensation reaction of o-phenylenediamines, diverse carbonyl compounds, and isocyanides in the presence of a catalytic amount of p-toluenesulfonic acid in good to excellent yields at room temperature is described.
authors.affiliation: Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran. ashaabani@cc.sbu.ac.ir
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shaabani
authors.forename: Ali
authors.initials: A
authors.lastname: Maleki
authors.forename: Hamid
authors.initials: H
authors.lastname: Mofakham
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Khavasi
mesh_terms: D002855:Chromatography, Thin Layer; D018360:Crystallography, X-Ray; D003486:Cyanides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003486:Cyanides; D011810:Quinoxalines