Versatile biologically inspired electronic neuron.
We present a biologically inspired electronic neuron based on a conductance model. The channels are constructed using linearly voltage controlled field effect transistors. A two channel and a three channel circuit is developed. The dynamical behavior of this system is studied, showing for the two channel circuit either class-I or class-II excitability and for the three channel circuit bursting and spike frequency adaptation. Voltage-clamp-type measurements, similar to the ones frequently used in neuroscience, are employed in order to determine the conductance characteristics of the electronic channels. We develop an empirical model based on these measurements that reproduces the different dynamical behaviors of the electronic neuron. We found that post-inhibitory rebound is present in the two channel circuit. Reliability and precision of spike timing is induced in the three channel circuit by injecting noise in the control variable of the slow channel that provides a negative feedback. The circuit is appropriate for the design of large scale electronic neural devices that can be used in mixed electronic-biological systems.
Sitt
Jacobo D
JD
Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón I, (1428) Buenos Aires, Argentina. jaco@df.uba.ar
Aliaga
J
J
D000200:Action Potentials / Q000502:physiology*; D040761:Biomimetic Materials; D004056:Differential Threshold / Q000502:physiology; D004581:Electronics / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D015640:Ion Channel Gating / Q000502:physiology; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D009435:Synaptic Transmission / Q000502:physiology*
D007473:Ion Channels