title: Cushing's Syndrome.
abstract: Cushing's syndrome is a rare endocrine disease characterized by cortisol hypersecretion, induced mainly by a pituitary tumor (Cushing's disease) or, rarely, by an adrenal or an ectopic neuroendocine tumor. Cushing's syndrome is associated with severe morbidities and an increased mortality. The major systemic complications and the main cause of death are represented by cardiovascular disease. The prognosis of the disease is mainly affected by the difficulties in the diagnosis and treatment of the disease, which remain a considerable challenge.
authors.affiliation: Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Via Sergio Pansini 5, 80131 Naples, Italy. rpivone@tin.it
authors.forename: Rosario
authors.initials: R
authors.lastname: Pivonello
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: De Martino
authors.forename: Monica
authors.initials: M
authors.lastname: De Leo
authors.forename: Gaetano
authors.initials: G
authors.lastname: Lombardi
authors.forename: Annamaria
authors.initials: A
authors.lastname: Colao
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000378:metabolism; D003480:Cushing Syndrome / Q000097:blood / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000627:therapeutic use
chemical_list: D004791:Enzyme Inhibitors; D018377:Neurotransmitter Agents; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone