Successful pregnancy in a patient with Landesman's Group C autosomal dominant polycystic kidney disease.
BACKGROUND
A female with autosomal dominant polycystic kidney disease was followed up over the course of four pregnancies. Her first three pregnancies were unsuccessful. Her fourth pregnancy resulted in a live birth, but at what expense?


METHODS
The diagnosis of autosomal dominant polycystic kidney disease was confirmed by ultrasound imaging. Physical examination, blood pressure measurement, and urine and blood analyses were performed at each follow-up visit.


METHODS
Deterioration of renal function following multiple complicated pregnancies.


RESULTS
Attention to blood pressure and proteinuria delayed initiation of dialysis, but effects of the number of pregnancies took their toll. The patient was started on hemodialysis and underwent renal transplantation.
Mohteshamzadeh
Mobin
M
Royal Berkshire NHS Foundation Trust, Reading, UK.
Coutinho
Andrew
A
Erekosima
Ibi
I
Rustom
Rana
R
Wong
Christopher F
CF
D000026:Abortion, Habitual; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003376:Counseling; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000145:classification / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D011256:Pregnancy Outcome; D006435:Renal Dialysis; D016216:Ultrasonography, Prenatal
D000959:Antihypertensive Agents; D003404:Creatinine