title: Discovery of chromone-based inhibitors of the transcription factor STAT5.
authors.affiliation: Max Planck Institute of Biochemistry, Department of Molecular Biology, Am Klopferspitz 18, 82152 Martinsried, Germany.
authors.forename: Judith
authors.initials: J
authors.lastname: Müller
authors.forename: Bianca
authors.initials: B
authors.lastname: Sperl
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Reindl
authors.forename: Anke
authors.initials: A
authors.lastname: Kiessling
authors.forename: Thorsten
authors.initials: T
authors.lastname: Berg
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D002867:Chromones / Q000737:chemistry / Q000494:pharmacology*; D004247:DNA / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D006835:Hydrazones / Q000737:chemistry / Q000494:pharmacology*; D008024:Ligands; D015394:Molecular Structure; D050799:STAT5 Transcription Factor / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects; D054852:Small Molecule Libraries; D013329:Structure-Activity Relationship; D018909:src Homology Domains / Q000187:drug effects
chemical_list: D000447:Aldehydes; D002867:Chromones; D006835:Hydrazones; D008024:Ligands; D050799:STAT5 Transcription Factor; D054852:Small Molecule Libraries; D004247:DNA