[Speech rhythm disorders due to synchronization induced in coupled inhibitory neurons].
Leaked-integrate-and-fire coupled oscillators (LIFs) were used as a model of electrophysiological activity. The activity of these oscillators determines the speech rhythm, which is governed by the square-law map with inhibition as a controlling parameter. Regular rhythms of convulsive repetitions at early stuttering are changed, however, by a mixture of repetitions and neurotic pauses. This mixture is a "stumbling block" for clinicians. Due to delays, only inhibitory LIFs are capable to create the synchronic activity in-phase or in-anti-phase at medial or at low coupling. This activity has the form of slow oscillations damping to the background level. Splashes of the activity above or below the level lead to neurotic disorders or to convulsive repetitions. Really, increased due to GABA the coupling leads to a reduction of stuttering.
Skliarov
O P
OP
D000200:Action Potentials; D006801:Humans; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D010507:Periodicity; D013342:Stuttering / Q000503:physiopathology*