title: 3-trifluoromethanesulfonamido-pyrrolidine: a general organocatalyst for anti-selective mannich reactions.
abstract: Mannich-type reactions of a glyoxylate imine with carbonyl compounds catalyzed by 3-trifluoromethanesulfonamidopyrrolidine proceed with high yields and anti-stereoselectivity. The catalyst is easily prepared and the transformation appears to be quite general accommodating aldehydes or ketones.
authors.affiliation: Laboratoire de Chimie Moléculaire et Thio-organique, ENSICAEN, Université de Caen Basse-Normandie, CNRS, 6 boulevard du Maréchal Juin, 14050 Caen, France.
authors.forename: Mickael
authors.initials: M
authors.lastname: Pouliquen
authors.forename: Jérôme
authors.initials: J
authors.lastname: Blanchet
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Lasne
authors.forename: Jacques
authors.initials: J
authors.lastname: Rouden