title: Successful conservative treatment of endocervical adenocarcinoma stage Ib1 diagnosed early in pregnancy.
abstract: Traditionally when cervical cancer is diagnosed during the first trimester of pregnancy, oncological treatment is given priority despite the pregnant state. A 32-year-old primigravida was diagnosed with invasive endocervical adenocarcinoma stage Ib1 at 8 weeks' gestation. As the patient wanted to preserve the pregnancy, an amputation of the anterior cervix and retroperitoneal pelvic lymphadenectomy were performed. Based on favourable prognostic markers, we decided to maintain the pregnancy with careful cytological and histological follow-up. The patient gave birth at term to a healthy boy, and 18 months after the delivery there is no evidence of recurrent disease. In the absence of poor prognostic markers, we decided to adopt a conservative approach for cervical adenocarcinoma in a pregnant patient at 8 weeks' gestation.
authors.affiliation: Gynecologic Oncology, Leuven Cancer Institute (LKI), Department of Obstetrics and Gynecology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Belgium.
authors.forename: Kristel
authors.initials: K
authors.lastname: Van Calsteren
authors.forename: Myriam
authors.initials: M
authors.lastname: Hanssens
authors.forename: Philippe
authors.initials: P
authors.lastname: Moerman
authors.forename: Guy
authors.initials: G
authors.lastname: Orye
authors.forename: Didier
authors.initials: D
authors.lastname: Bielen
authors.forename: Ignace
authors.initials: I
authors.lastname: Vergote
authors.forename: Frederic
authors.initials: F
authors.lastname: Amant
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000601:surgery*; D000328:Adult; D002584:Cervix Uteri / Q000601:surgery; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000601:surgery*; D011261:Pregnancy Trimester, First; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000601:surgery*