title: [Association of the degree of bronchial epithelial dysplasia to the serum level of non-enzymatic antioxidants].
abstract: The serum levels of non-enzymatic antioxidants were studied in patients with chronic nonspecific lung diseases with first-to-third-degree dysplasia of the bronchial epithelium (BE) before and after therapeutic correction. The development of BE dysplastic changes was ascertained to cause a considerable reduction in the content of antioxidant vitamin A. During the therapy contributing to reversal of BE dysplastic alterations, there was an increase in the serum levels of vitamin A and uric acid in patients with simple chronic bronchitis with both first- and second-degree dysplasia. If no therapeutic effect occurred, the systemic level of the antioxidants remained unchanged.
authors.forename: I V
authors.initials: IV
authors.lastname: Kondakova
authors.forename: O V
authors.initials: OV
authors.lastname: Cheremisina
authors.forename: G V
authors.initials: GV
authors.lastname: Kakurina
authors.forename: E L
authors.initials: EL
authors.lastname: Choĭnzonov
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D001984:Bronchial Neoplasms / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D029481:Bronchitis, Chronic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D014527:Uric Acid / Q000097:blood*; D014801:Vitamin A / Q000097:blood*
chemical_list: D000975:Antioxidants; D014801:Vitamin A; D014527:Uric Acid