title: Dynamics of hydration of cicatricial tissue during local therapy with collagenase preparations.
abstract: The components of complex dielectric permeability of cicatricial tissue at the frequency of 55 GHz were studied during local therapy of cicatrices with Fermenkol (a complex of collagenolytic proteases). Electrical characteristics of tissues in the microwave range were interpreted in terms of hydration parameters (total content of water in tissues and the ratio of structured and free water). The rightfulness of interpretations is discussed on the basis of the results of measurements of cell suspension models (native blood and its fractions brought to a standard hematocrit). The results attest to a relationship between hydration of the cicatricial tissue and its morphology and function.
authors.affiliation: Vysokie Tekhnologii Research-and-Production Complex, St Petersburg, Russia.
authors.forename: A N
authors.initials: AN
authors.lastname: Kuznetsov
authors.forename: I I
authors.initials: II
authors.lastname: Turkovsky
authors.forename: B A
authors.initials: BA
authors.lastname: Paramonov
authors.forename: A A
authors.initials: AA
authors.lastname: Panferov
authors.forename: O A
authors.initials: OA
authors.lastname: Klimova
authors.forename: A V
authors.initials: AV
authors.lastname: Zhadaev
mesh_terms: D002921:Cicatrix / Q000188:drug therapy* / Q000378:metabolism; D017364:Collagenases / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D010539:Permeability; D014867:Water / Q000378:metabolism*
chemical_list: D014867:Water; D017364:Collagenases