Zinc therapy for night blindness in cystic fibrosis.
This is the first report of a supplemented CF patient presenting with clinical vitamin A deficiency to be successfully treated with zinc therapy alone. Therefore in addition to retinol supplementation, normalizing serum zinc levels may be important in maintaining the vitamin A status of CF patients. The interactions and synergistic effects between the two micronutrients are discussed.
Tinley
Christopher G
CG
West of England Eye Unit, Royal Devon and Exeter Hospital (Wonford), Barrack Road, Exeter, EX2 5DW, UK. Electronic address: cgtinley@doctor.com.
Withers
Nicholas J
NJ
Royal Devon and Exeter Hospital (Wonford), UK.
Sheldon
Christopher D
CD
Royal Devon and Exeter Hospital (Wonford), UK.
Quinn
Anthony G
AG
West of England Eye Unit, Royal Devon and Exeter Hospital (Wonford), Barrack Road, Exeter, EX2 5DW, UK.
Jackson
Alan A
AA
Institute of Human Nutrition, Developmental Origins of Health and Disease Division, University of Southampton, Southampton General Hospital (MP 113), Tremona Road, Southampton, SO16 6YD, UK.
D003550:Cystic Fibrosis / Q000150:complications; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D009755:Night Blindness / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D014131:Trace Elements / Q000627:therapeutic use*; D055815:Young Adult; D015032:Zinc / Q000172:deficiency*; D019287:Zinc Sulfate / Q000627:therapeutic use*
D014131:Trace Elements; D019287:Zinc Sulfate; D015032:Zinc