title: Phellifuropyranone A: a new furopyranone compound isolated from fruit bodies of wild Phellinus linteus.
abstract: A new furopyranone, phellifuropyranone A, was isolated from fruit bodies of wild Phellinus linteus as well as phelligridin G, and their chemical structures were determined by various spectroscopic methods including measurement of NMR spectra. Phellifuropyranone A together with meshimakobnol A and meshimakobnol B showed antiproliferative activity against mouse melanoma cells and human lung cancer cells in vitro.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kojima
authors.forename: Takamasa
authors.initials: T
authors.lastname: Ohno
authors.forename: Makoto
authors.initials: M
authors.lastname: Inoue
authors.forename: Hajime
authors.initials: H
authors.lastname: Mizukami
authors.forename: Akito
authors.initials: A
authors.lastname: Nagatsu
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification / Q000494:pharmacology*; D001487:Basidiomycota / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D011753:Pyrones / Q000302:isolation & purification / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000903:Antibiotics, Antineoplastic; D011753:Pyrones; C527214:phellifuropyranone A