Acantholytic dyskeratotic acanthoma: a variant of a benign keratosis.
Acantholytic acanthoma was originally described as a solitary lesion displaying histologic features of acantholysis without dyskeratosis. Solitary, non-genital lesions displaying confluent acantholysis and dyskeratosis have not been well described in the literature, clinically or histologically. We screened cases at our institution over a 6-month period and found 28 such lesions. Lesions were most often found on the trunk as a solitary papule, for which the clinical diagnosis was often basal cell carcinoma. There was a slight female predominance. Confluent acantholysis and dyskeratosis is a histologic pattern that may present as a solitary keratosis.
Ko
Christine J
CJ
Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA. christine.ko@yale.edu
Barr
Ronald J
RJ
Subtil
Antonio
A
McNiff
Jennifer M
JM
D000051:Acantholysis / Q000150:complications / Q000473:pathology*; D049309:Acanthoma / Q000150:complications / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007642:Keratosis / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*