Enzyme inhibition activities of Teucrium royleanum.
The crude methanolic extract and chloroform, ethyl acetate and n-butanol fractions of Teucrium royleanum were examined as inhibitors of actylcholinesterase, butyrylcholinesterase, lipoxygenase and urease. A significant enzyme inhibition activity (52-83%) was shown by the crude methanolic extract and its fractions against acetylcholinesterase, while low to outstanding enzyme inhibitory activity was shown (19-93%) against butyrylcholinesterase. The crude methanolic extract and its various fractions demonstrated low activity against lipoxygenase and inactive against urease.
Ahmad
Bashir
B
Center for Biotechnology, University of Peshawar, NWFP, Pakistan. bashirdr2001@yahoo.com
Mukarram Shah
S M
SM
Khan
Haroon
H
Hassan Shah
S M
SM
D000110:Acetylcholinesterase / Q000378:metabolism*; D002265:Carboxylic Ester Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D031367:Teucrium / Q000737:chemistry*
D004791:Enzyme Inhibitors; D010936:Plant Extracts; D002265:Carboxylic Ester Hydrolases; C021487:butyrylesterase; D000110:Acetylcholinesterase