CT-guided permanent brachytherapy for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC).
Seven patients with early stage T1N0M0 NSCLC who had medical contraindications for surgical resection were treated with CT-guided percutaneous implantation of (103)Pd or (125)I seeds. After the procedure, two patients developed pneumothorax and hemo/pneumothorax that was managed with aspirative drainage. One patient developed a focal pneumonitis 3 months after the procedure. After a median follow-up of 13 months (4.6-41.0+ months), no patient has developed local or regional failure.
Martínez-Monge
Rafael
R
Department of Oncology, Clínica Universitaria de Navarra, University of Navarra, Avda Pío XII s/n, Pamplona, Navarre, Spain. rmartinezm@unav.es
Pagola
María
M
Vivas
Isabel
I
López-Picazo
José María
JM
D000279:Administration, Cutaneous; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D000075202:Contraindications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007457:Iodine Radioisotopes; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010165:Palladium; D011183:Postoperative Complications / Q000601:surgery; D011868:Radioisotopes; D019616:Thoracic Surgical Procedures; D015898:Tomography Scanners, X-Ray Computed
D007457:Iodine Radioisotopes; D011868:Radioisotopes; D010165:Palladium