title: Site isolated base and acid catalyzed azaspirocyclization cascades.
abstract: A one-pot, site isolated base (PS-BEMP) and acid (Si-TsOH) catalyzed cyclization cascade to azaspirocyclic molecules is reported; the reaction is simple to perform, atom efficient (water is the only byproduct) and broad in its scope to a diverse range of azaspirocyclic products.
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, UK.
authors.forename: Adam W
authors.initials: AW
authors.lastname: Pilling
authors.forename: Jutta
authors.initials: J
authors.lastname: Böhmer
authors.forename: Darren J
authors.initials: DJ
authors.lastname: Dixon