title: Degradation kinetics of butylmethoxydibenzoylmethane (avobenzone) in aqueous solution.
abstract: The degradation kinetics of avobenzone in aqueous solution was studied at 60 +/- 0.2 degrees C over a pH range of 2.0-10.0. The degradation rates were determined by high performance liquid chromatography. The reaction is found to follow first-order kinetics and the rate constant for the decomposition at 25 degrees C is estimated by extrapolation. The breakdown of avobenzone is shown to be hydroxide ion catalyzed and the Arrhenius plots showed the temperature dependence of avobenzone degradation.
authors.affiliation: DMI Inc., Wharton, NJ USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Mbah
mesh_terms: D000465:Algorithms; D002021:Buffers; D047188:Chalcones / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D019999:Pharmaceutical Solutions; D011427:Propiophenones; D013696:Temperature; D014867:Water
chemical_list: D002021:Buffers; D047188:Chalcones; D019999:Pharmaceutical Solutions; D011427:Propiophenones; D014867:Water; C049935:avobenzone