[Differentiated approach to the therapy of endogenous anxious depression].
The paper presents a study devoted to endogenous depression with a pronounced element of anxiety. The subjects, 66 patients, received antidepresive therapy with either amitriptyline or remeron. The study lasted 6 months, during which the symptoms were assessed using Hamilton Depression and Anxiety Scales. Three variants of anxious depressive conditions were revealed: anxious melancholic, anxious hypochondriac and anxious adynamic ones. Amitriptyline proved to be more efficient in treatment of patients with anxious melancholic depression. No difference in time to and the degree of symptom reduction was observed between amitriptyline and remeron in patients with anxious adynamic depression. Remeron proved to be more efficient in patients with anxious hypochondriac depression.
Shchukina
E P
EP
Kinkul'kina
M A
MA
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001007:Anxiety / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D002250:Carbon Radioisotopes; D003863:Depression / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D000078785:Mirtazapine; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
D000929:Antidepressive Agents, Tricyclic; D002250:Carbon Radioisotopes; D008803:Mianserin; D000078785:Mirtazapine