title: Pregnancy and active Huntington disease: a rare combination.
abstract: We describe the complicated course of a rare pregnant woman with symptomatic Huntington disease (HD) and discuss multidisciplinary care issues that may be encountered. A 31-year-old gravida 2, para 1 with advanced HD was admitted at 30 weeks gestation for preterm labor. Her course was complicated by progressive cognitive and physical impairment, dysphagia, malnutrition, diabetes insipidus, aspiration pneumonia, chorioamnionitis, preterm delivery and pyelonephritis. Pregnant women with symptomatic HD may present multiple challenges requiring extensive multidisciplinary input.
authors.affiliation: Department of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL 35249-7333, USA. kelly.hoskins@obgyn.uab.edu
authors.forename: K E
authors.initials: KE
authors.lastname: Hoskins
authors.forename: A T N
authors.initials: AT
authors.lastname: Tita
authors.forename: J R
authors.initials: JR
authors.lastname: Biggio
authors.forename: P S
authors.initials: PS
authors.lastname: Ramsey
mesh_terms: D000328:Adult; D002821:Chorioamnionitis / Q000453:epidemiology; D003919:Diabetes Insipidus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000453:epidemiology; D007751:Labor, Induced; D018529:Nutritional Support; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011704:Pyelonephritis / Q000453:epidemiology