Successful treatment of small cell lung cancer during pregnancy.
The incidence of malignancy associated with pregnancy is rising. This issue is of increasing importance in lung cancer given the rising number of cases of lung cancer in women, many of childbearing age. Treatment with chemotherapy in patients who are pregnant is indicated in scenarios where the malignancy is aggressive and the risk of death of the mother outweighs the risk of fetal effects from chemotherapy. We report a case of a pregnant female with limited stage small cell lung carcinoma treated at 27 weeks gestation with cisplatin and etoposide and subsequent delivery of a healthy child.
Kluetz
Paul G
PG
University of Maryland, Department of Internal Medicine, MD 21201, United States.
Edelman
Martin J
MJ
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000150:complications / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
D005047:Etoposide; D002945:Cisplatin