Structural changes in visual cortex area 17 in children with aftereffects of perinatal injury to the central nervous system.
Structural characteristics of the visual cortex area 17 were studied by computer morphometry on autopsied specimens of the brain from children with perinatal injury to the central nervous system and in a group of control children without symptoms of brain injury. In children with perinatal pathology, the thickness of the cortex and its individual layers (IV, V, VI+VII) increased unevenly during the 1st year of life, the density of neurons decreased, while the content of neuroglia increased. These disorders reflect nonspecific structural and functional changes in the visual cortex associated with perinatal cerebral pathology.
Sal'kov
V N
VN
Laboratory of Functional Morphochemistry, Institute of Brain Research, Russian Academy of Medical Sciences, Moscow. neurolab@yandex.ru
Khudoerkov
R M
RM
D002490:Central Nervous System / Q000293:injuries*; D002547:Cerebral Palsy / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009457:Neuroglia / Q000473:pathology; D009474:Neurons / Q000473:pathology; D014793:Visual Cortex / Q000473:pathology*