title: Sister Mary Joseph's nodule as the first sign of pregnancy-associated gastric cancer: a case report.
abstract: Sister Mary Joseph's nodule is an inconspicuous and uncommon clinical sign of advanced malignant disease, especially gastric cancer. Pregnancy-associated gastric cancer is an extremely rare condition and can be difficult to diagnose, due to the absence or misinterpretation of symptoms as pregnancy-related. Diagnostic aids, such as a basic chemistry panel and imaging techniques, may not show any abnormalities. We present a case of a 37-year-old pregnant patient whose umbilical nodule was the first presenting physical sign of gastric cancer, which had metastasized throughout the abdominal and pelvic regions.
authors.affiliation: Obstetrics and Gynecology Department, Medical Faculty of Ottovon-Guericke University, Magdeburg, Germany.
authors.forename: Sara
authors.initials: S
authors.lastname: Fill
authors.forename: Andrei
authors.initials: A
authors.lastname: Taran
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Schulz
authors.forename: Stefan
authors.initials: S
authors.lastname: Kahl
authors.forename: Thomas
authors.initials: T
authors.lastname: Kalinski
authors.forename: Bobbie
authors.initials: B
authors.lastname: Smith
authors.forename: Serban-Dan
authors.initials: SD
authors.lastname: Costa
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology; D014472:Umbilicus / Q000473:pathology*