title: [Analysis on the proportion of reported hepatitis B cases through pilot surveillance in China during 2006].
abstract: OBJECTIVE
  To better understand the proportions of reported hepatitis B cases in pilot surveillance cites through investigation and laboratory testing.
  
  
  METHODS
  To confirm the reported cases of hepatitis B by collecting blood specimen and laboratory testing on HBsAg, IgM of Anti-HBc, Anti-HAV in 18 pilot surveillance counties.
  
  
  RESULTS
  Among 2858 cases of hepatitis B reported in 2006, 23.97% of them were reported as suspected acute cases, 14.87% as acute cases, 20.33% as suspected chronic cases, 34.67% as chronic cases, 4.09% as cirrhosis and 2.06% as HCC. Among 1681 reported hepatitis B cases confirmed by laboratory testing, results showed that 24.16% of them were diagnosed as acute hepatitis B, but only 15.37% were confirmed as acute hepatitis B. Although the proportion confirmed as hepatitis B kept consistent as before, misclassification was found.
  
  
  CONCLUSIONS
  In current surveillance system, reported hepatitis B cases were mainly chronic, only up to one third belonged to acute hepatitis B. The reported incidence of hepatitis B did not reflect the real incidence due to misclassification. To better define the burden on hepatitis B disease, it was necessary and urgent to revise the diagnostic criteria and to conduct surveillance on hepatitis B, under separate reporting categories which including acute and chronic cases of the disease.
authors.affiliation: National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Fu-Qiang
authors.initials: FQ
authors.lastname: Cui
authors.forename: Yong
authors.initials: Y
authors.lastname: Lu
authors.forename: Fu-Zhen
authors.initials: FZ
authors.lastname: Wang
authors.forename: Yuan-Sheng
authors.initials: YS
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Zheng
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Gong
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Han
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Dong
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.forename: Luo-Ya
authors.initials: LY
authors.lastname: Ling
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Lin-Qi
authors.initials: LQ
authors.lastname: Diao
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Shao
authors.forename: Gang
authors.initials: G
authors.lastname: Fang
authors.forename: Li
authors.initials: L
authors.lastname: Gao
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Liang
mesh_terms: D002681:China / Q000453:epidemiology; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006801:Humans; D015994:Incidence; D010865:Pilot Projects; D011159:Population Surveillance
chemical_list: D006510:Hepatitis B Antibodies