title: Translating the diabetes prevention program into a hospital-based weight loss program.
abstract: OBJECTIVE
  Intensive lifestyle interventions have established efficacy, but translation to real-world settings has not been well demonstrated. Using the diffusion of innovations model, we describe the adoption of the Diabetes Prevention Program (DPP) Lifestyle Intervention into a hospital-based program and report feasibility, acceptability, and outcomes.
  
  
  METHODS
  Patients (N = 118; 72% female, mean age = 48.8, mean baseline body mass index = 43.3) were enrolled into 16 weeks of DPP.
  
  
  METHODS
  Weight loss (kg) was measured at baseline and after treatment.
  
  
  RESULTS
  Mean weight loss after 16 weeks was 5.57 kg (SD = 4.6) or 4.6% of baseline weight, and 30% met the 7% weight loss goal. Outcomes are compared with those reported in the DPP trial. Most participants (90.4%) were satisfied with the service; however, only 56% were satisfied with their weight loss.
  
  
  CONCLUSIONS
  The DPP was successfully translated into a real-world clinic with some protocol modifications. Weight loss was modest among heavier patients with more comorbidities than the original DPP sample. Diffusion of innovations theory provides a useful framework for adopting evidence-based programs in the clinical setting.
authors.affiliation: Department of Medicine, Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, MA, USA. Sherry.pagoto@umassmed.edu
authors.forename: Sherry L
authors.initials: SL
authors.lastname: Pagoto
authors.forename: Lyle
authors.initials: L
authors.lastname: Kantor
authors.forename: Jamie S
authors.initials: JS
authors.lastname: Bodenlos
authors.forename: Mitchell
authors.initials: M
authors.lastname: Gitkind
authors.forename: Yunsheng
authors.initials: Y
authors.lastname: Ma
mesh_terms: D000328:Adult; D003920:Diabetes Mellitus / Q000517:prevention & control*; D004059:Diffusion of Innovation; D005260:Female; D006293:Health Promotion / Q000458:organization & administration*; D006761:Hospitals; D006801:Humans; D008297:Male; D008404:Massachusetts; D008875:Middle Aged; D040242:Risk Reduction Behavior; D015431:Weight Loss