title: A study into the characteristics and outcome of variceal bleeding in a tertiary hospital in Southeast Asia.
abstract: This retrospective study evaluated patients admitted to the Department of Gastroenterology, Singapore General Hospital for variceal bleeding in the year 2004. Improvement in outcome of variceal bleeding has been reported in the West. There is no regional data on this condition. This study aims to determine the characteristics and outcome of variceal bleeding in a tertiary hospital in Southeast Asia. Twenty-two patients were eligible. The main aetiologies of liver cirrhosis were chronic hepatitis B (38%) and alcohol (33%). Child's A, B and C were 29%, 48% and 24% respectively. Nineteen patients (86%) had bleeding oesophageal varices (band ligation performed). The remaining three patients (14%) had bleeding gastric varices (N-butyl-2-cyanoacrylate injection performed). Detailed description of certain endoscopic findings was absent in up to 18 patients (82%). All patients received antibiotics and vasoactive drug. In-hospital mortality and rebleeding were 9% and 18% respectively. We conclude that the relatively low in-hospital mortality and rebleeding rates in our series are most probably due to the smaller proportion of patients with severe liver dysfunction and management which adhered to recommendations. Documentation of endoscopic findings needs to be improved to facilitate the continuation of care.
authors.affiliation: Department of Gastroenterology and Hepatology, Singapore General Hospital, Outram Road, Singapore 169608.
authors.forename: B S
authors.initials: BS
authors.lastname: Yew
authors.forename: W C
authors.initials: WC
authors.lastname: Ong
authors.forename: W C
authors.initials: WC
authors.lastname: Chow
authors.forename: H F
authors.initials: HF
authors.lastname: Lui
mesh_terms: D000368:Aged; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D008103:Liver Cirrhosis; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012846:Singapore / Q000453:epidemiology