title: Serum creatinine stabilization following renal artery stenting.
abstract: The impact of renal artery stenting on renal function in a subgroup of consecutive de novo patients with atherosclerotic renal artery stenosis from the single operator, single center, retrospective renal stent trial is defined. Patients with inadequate preprocedure and/or follow-up renal function studies were excluded. Abnormal baseline serum creatinine (sCr) was defined as > or = 1.5 mg/dL. Follow-up sCr was improved, unchanged, or worsened if the variance from baseline decreased by >20%, stayed within 20%, or increased >20%, respectively. For the total cohort (194 patients), renal function stabilized or improved in 72% of patients. Plotting 1/sCr demonstrated a decline in renal function before the procedure that stabilized following renal artery stenting. Bilateral renal artery stenting predicted normal follow-up sCr, and baseline sCr >2.1 mg/dL was associated with improvement in sCr long-term. In conclusion, renal artery stenting results in overall stabilization of renal function, and bilateral renal artery stenting seems to have added benefit.
authors.affiliation: Vascular Center of Excellence, Charleston Area Medical Center Research Institute, Charleston, WV, USA. mbates@camc.org
authors.forename: Mark C
authors.initials: MC
authors.lastname: Bates
authors.forename: John E
authors.initials: JE
authors.lastname: Campbell
authors.forename: Mike
authors.initials: M
authors.lastname: Broce
authors.forename: Philip S
authors.initials: PS
authors.lastname: Lavigne
authors.forename: Mary A
authors.initials: MA
authors.lastname: Riley
mesh_terms: D000368:Aged; D016009:Chi-Square Distribution; D003404:Creatinine / Q000097:blood*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D012078:Renal Artery Obstruction / Q000097:blood / Q000601:surgery*; D012189:Retrospective Studies; D015607:Stents
chemical_list: D003404:Creatinine