Portable X-band system for solution state dynamic nuclear polarization.
This paper concerns instrumental approaches to obtain large dynamic nuclear polarization (DNP) enhancements in a completely portable system. We show that at fields of 0.35 T under ambient conditions and at X-band frequencies, 1H enhancements of >100-fold can be achieved using nitroxide radical systems, which is near the theoretical maximum for 1H polarization using the Overhauser effect at this field. These large enhancements were obtained using a custom built microwave transmitter and a commercial TE102 X-band resonant cavity. The custom built microwave transmitter is compact, so when combined with a permanent magnet it is readily transportable. Our commercial X-band resonator was modified to be tunable over a range of approximately 9.5-10 GHz, giving added versatility to our fixed field portable DNP system. In addition, a field adjustable Halbach permanent magnet has also been employed as another means for matching the electron spin resonance condition. Both portable setups provide large signal enhancements and with improvements in design and engineering, greater than 100-fold 1H enhancements are feasible.
Armstrong
Brandon D
BD
Department of Physics, University of California, Santa Barbara, CA 93106, USA.
Lingwood
Mark D
MD
McCarney
Evan R
ER
Brown
Elliott R
ER
Blümler
Peter
P
Han
Songi
S
D004867:Equipment Design; D019544:Equipment Failure Analysis; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation* / Q000379:methods; D008872:Microwaves; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity