Meningitis resulting in hearing loss and labyrinthitis ossificans - does the causative organism matter?
Our aim was to demonstrate whether one causative agent of meningitis is more likely to cause profound hearing loss and labyrinthitis ossificans. We obtained data from the New South Wales health department for cases of meningitis between 1995 and 2005 (1568 cases) and the Sydney Cochlear Implant Centre for cochlear implant patients with hearing loss secondary to meningitis from 1984 to 2005 (70 ears in 59 patients). The aetiological agents were compared with regard to their ability to cause profound hearing loss and cochlear ossification. Neisseria meningitidis resulted in 56.9% of cases of meningitis and 11.4% of the cases of profound hearing loss resulting in cochlear implantation (incidence of profound hearing loss of 0.4%). Streptococcus pneumoniae, however, caused 41.1% of meningitis but 85.7% of cochlear implantation (incidence of 4.6%). Labyrinthitis ossificans was more common after infection with Streptococcus pneumoniae but there was no statistically significant difference between Streptococcus pneumoniae, Haemophilus influenzae or Neisseria meningitidis for labyrinthitis ossificans (p = 0.45, chi-squared test). In conclusion Neisseria meningitidis meningitis carries a very low risk of profound hearing loss but Streptococcus pneumoniae meningitis a significantly higher risk.
Douglas
Susan A
SA
The Sydney Cochlear Implant Centre, University of Sydney, Sydney Australia. SusanADouglas@gmail.com
Sanli
Halit
H
Gibson
William P R
WP
D000293:Adolescent; D000328:Adult; D001315:Australia; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000473:pathology; D019929:Cochlear Implantation; D005260:Female; D006193:Haemophilus influenzae; D034381:Hearing Loss / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007223:Infant; D007762:Labyrinthitis / Q000382:microbiology* / Q000473:pathology; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications / Q000382:microbiology*; D009345:Neisseria meningitidis; D009999:Ossification, Heterotopic / Q000382:microbiology / Q000473:pathology; D012189:Retrospective Studies; D013296:Streptococcus pneumoniae