title: Neuroimaging and neurodevelopmental outcomes in preterm infants.
abstract: Imaging of the preterm infant brain has advanced dramatically beyond the earliest era of transillumination. Computed tomography (CT), a crucial innovation during the early 1970s, allowed noninvasive visualization of intracerebral lesions, particularly hemorrhage. The capability to document brain injury in the preterm infant led to better clarification of links to developmental outcomes. With the development of cranial ultrasound (CUS), and more recently, magnetic resonance imaging (MRI), CT is used rarely for imaging the brain of preterm infants. Despite extensive experience with neonatal neuroimaging, significant questions still remain. Substantial controversies exist pertaining to when and how neuroimaging should be performed and how images should be interpreted.
authors.affiliation: Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA. srhintz@stanford.edu
authors.forename: Susan R
authors.initials: SR
authors.lastname: Hintz
authors.forename: Michael
authors.initials: M
authors.lastname: O'Shea
mesh_terms: D001921:Brain / Q000196:embryology / Q000254:growth & development / Q000473:pathology*; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D002657:Child Development; D004453:Echoencephalography / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging; D007236:Infant, Small for Gestational Age; D019102:Infant, Very Low Birth Weight; D008279:Magnetic Resonance Imaging; D009424:Nervous System Physiological Phenomena