[Aminoglycosides therapy in patients with bacteraemia].
Metaanalyses have questioned the use of aminoglycosides (AG). We studied the association between AG therapy, mortality and impairment of renal function among patients with bacteraemia who were given appropriate empirical antibiotic therapy with or without AG. Thirty-day mortality was similar in the two groups. AG was associated with decreased mortality in patients with a urinary tract or abdominal focus and with increased mortality in patients with pneumonia. AG therapy modestly increased the risk of rise in serum creatinine. AG therapy appears equivalent to other covering antibiotic regimens.
Freundlich
Morten
M
Arhus Universitetshospital, Aalborg Sygehus, Aalborg.
Thomsen
Reimar W
RW
Pedersen
Lars
L
West
Hans
H
Schønheyder
Henrik C
HC