title: Judah Folkman, a pioneer in the study of angiogenesis.
abstract: More than 30 years ago, Judah Folkman found a revolutionary new way to think about cancer. He postulated that in order to survive and grow, tumors require blood vessels, and that by cutting off that blood supply, a cancer could be starved into remission. What began as a revolutionary approach to cancer has evolved into one of the most exciting areas of scientific inquiry today. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.
authors.affiliation: Department of Human Anatomy and Histology, University of Bari Medical School, Piazza G. Cesare, 11, Policlinico, 70124, Bari, Italy. ribatti@anatomia.uniba.it
authors.forename: Domenico
authors.initials: D
authors.lastname: Ribatti
mesh_terms: D020533:Angiogenesis Inhibitors / Q000266:history* / Q000627:therapeutic use; D000818:Animals; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009369:Neoplasms / Q000098:blood supply* / Q000266:history* / Q000378:metabolism / Q000503:physiopathology; D009389:Neovascularization, Pathologic / Q000266:history* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D014481:United States
chemical_list: D020533:Angiogenesis Inhibitors