title: "Candidatus Cloacamonas acidaminovorans": genome sequence reconstruction provides a first glimpse of a new bacterial division.
abstract: Many microorganisms live in anaerobic environments. Most of these microorganisms have not yet been cultivated. Here, we present, from a metagenomic analysis of an anaerobic digester of a municipal wastewater treatment plant, a reconstruction of the complete genome of a bacterium belonging to the WWE1 candidate division. In silico proteome analysis indicated that this bacterium might derive most of its carbon and energy from the fermentation of amino acids, and hence, it was provisionally classified as "Candidatus Cloacamonas acidaminovorans." "Candidatus Cloacamonas acidaminovorans" is probably a syntrophic bacterium that is present in many anaerobic digesters. This report highlights how environmental sequence data might provide genomic and functional information about a new bacterial clade whose members are involved in anaerobic digestion.
authors.affiliation: CEA/Genoscope, CNRS-UMR8030, Université d'Evry Val d'Essonne, 91057 Evry, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Pelletier
authors.forename: Annett
authors.initials: A
authors.lastname: Kreimeyer
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Bocs
authors.forename: Zoé
authors.initials: Z
authors.lastname: Rouy
authors.forename: Gábor
authors.initials: G
authors.lastname: Gyapay
authors.forename: Rakia
authors.initials: R
authors.lastname: Chouari
authors.forename: Delphine
authors.initials: D
authors.lastname: Rivière
authors.forename: Akila
authors.initials: A
authors.lastname: Ganesan
authors.forename: Patrick
authors.initials: P
authors.lastname: Daegelen
authors.forename: Abdelghani
authors.initials: A
authors.lastname: Sghir
authors.forename: Georges N
authors.initials: GN
authors.lastname: Cohen
authors.forename: Claudine
authors.initials: C
authors.lastname: Médigue
authors.forename: Jean
authors.initials: J
authors.lastname: Weissenbach
authors.forename: Denis
authors.initials: D
authors.lastname: Le Paslier
mesh_terms: D000693:Anaerobiosis; D001419:Bacteria / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D016680:Genome, Bacterial; D023281:Genomics / Q000379:methods*; D008954:Models, Biological; D008957:Models, Genetic; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial