[A new coumarin glycoside from Glehnia littoralis].
To study the chemical constituents from Glehnia littoralis, macroreticular resin column chromatography, repeated column chromatography on Sephadex LH-20 and reverse phase ODS were used to isolate the compounds whose structures were elucidated based on spectroscopic data (ESI-MS, 1D and 2D NMR). A new coumarin glycoside was isolated and identified as: bergaptol 5-O-beta-D-gentiobioside (1), along with eight known compounds: (7R, 8S)-dehydrodiconiferylalcohol-4, 9-di-O-beta-D-glucoside (2), cirtrusin A (3), (-)-seco-isolariciresinol 4-O-beta-D-glucopyranoside (4), baihuaqianhuside (5), xanthotoxol 8-O-beta-D-glucopyranoside (6), 5'-methylthioadenosine (7), adenosine (8), L-tryptophan (9). Compound 1 is a new coumarin glycoside, compounds 2 and 7 were isolated from this genus for the first time.
Zhao
Ya
Y
Department of Analysis of Traditional Chinese Medicine, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yuan
Zhong
Z
D019661:Apiaceae / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D003839:Deoxyadenosines / Q000737:chemistry / Q000302:isolation & purification*; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D013872:Thionucleosides / Q000737:chemistry / Q000302:isolation & purification*
D003374:Coumarins; D003839:Deoxyadenosines; D004187:Disaccharides; D011564:Furocoumarins; D006027:Glycosides; D013872:Thionucleosides; C542807:bergaptol 5-O-gentiobioside; C008500:5'-methylthioadenosine