title: Systems for applied gene control in Saccharomyces cerevisiae.
abstract: Saccharomyces cerevisiae is frequently used in biotechnology, including fermentative processes in food production, heterologous protein production and high throughput developments for biomedicine. Accurate expression of selected genes is essential for all these areas. Systems that can be regulated are particularly useful because they allow controlling the timing and levels of gene expression. We examine here new expression systems that have been described, including improvements of classical ones and new strategies of artificial gene control that have been applied in functional genomics.
authors.affiliation: Departamento de Genética, Universidad de Sevilla, Avda. Reina Mercedes 6, 41012, Seville, Spain.
authors.forename: Douglas
authors.initials: D
authors.lastname: Maya
authors.forename: María José
authors.initials: MJ
authors.lastname: Quintero
authors.forename: María
authors.initials: M
authors.lastname: de la Cruz Muñoz-Centeno
authors.forename: Sebastián
authors.initials: S
authors.lastname: Chávez
mesh_terms: D000693:Anaerobiosis; D002352:Carrier Proteins / Q000235:genetics; D005686:Galactokinase / Q000235:genetics; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D005818:Genetic Engineering; D023281:Genomics; D008668:Metallothionein; D009875:Operator Regions, Genetic; D011401:Promoter Regions, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000254:growth & development; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D014158:Transcription, Genetic; D019076:Transgenes
chemical_list: C500769:CUP1-1 protein, S cerevisiae; D002352:Carrier Proteins; D029701:Saccharomyces cerevisiae Proteins; D008668:Metallothionein; C524219:GAL1 protein, S cerevisiae; D005686:Galactokinase