Successful full-term pregnancies with assisted reproduction supported with prednisolone, acetylsalicylic acid and high progesterone doses in a lupus patient.
We present two rare cases of successful full-term pregnancies in a young woman suffering from lupus erythematosus for two years, who had subfertility problems and two missed abortions, before and after the diagnosis of lupus, with assisted reproduction. She received 10 mg of prednisolone daily from ovulation induction (with recombinant FSH--50 IU) until delivery, together with acetylsalicylic acid from ovulation induction until the 37th week of gestation and finally progesterone in high doses from the last insemination until the 12th week of gestation.
Trakakis
E
E
Third Department of Obstetrics and Gynecology, University of Athens, Attikon, University Hospital, Greece.
Loghis
C
C
Laggas
D
D
Simeonides
G
G
Vaggopoulos
V
V
Chrelias
C
C
Lambos
G
G
Kassanos
D
D
D000282:Administration, Intravaginal; D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D007315:Insemination, Artificial; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy*; D010062:Ovulation Induction; D011239:Prednisolone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications; D011374:Progesterone / Q000008:administration & dosage*; D011372:Progestins / Q000008:administration & dosage*; D047929:Term Birth
D000893:Anti-Inflammatory Agents; D011372:Progestins; D011374:Progesterone; D011239:Prednisolone; D001241:Aspirin