title: Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry.
abstract: This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions.
authors.affiliation: Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, UK. M.Baker-2@postgrad.manchester.ac.uk
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Baker
authors.forename: Michael D
authors.initials: MD
authors.lastname: Brown
authors.forename: Ehsan
authors.initials: E
authors.lastname: Gazi
authors.forename: Noel W
authors.initials: NW
authors.lastname: Clarke
authors.forename: John C
authors.initials: JC
authors.lastname: Vickerman
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Lockyer
mesh_terms: D045744:Cell Line, Tumor; D016002:Discriminant Analysis; D006801:Humans; D008297:Male; D025341:Principal Component Analysis / Q000379:methods; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D018629:Spectrometry, Mass, Secondary Ion / Q000379:methods*