title: [Expression of trophinin in human oocytes and preimplantation embryos].
abstract: OBJECTIVE
  To investigate the significance of trophinin expression in human oocytes and preimplantation embryos.
  
  
  METHODS
  The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.
  
  
  RESULTS
  Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).
  
  
  CONCLUSIONS
  Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.
authors.affiliation: Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Hua-Yun
authors.initials: HY
authors.lastname: Wang
authors.forename: Fu-Qi
authors.initials: FQ
authors.lastname: Xing
authors.forename: Shi-Ling
authors.initials: SL
authors.lastname: Chen
mesh_terms: D001755:Blastocyst / Q000378:metabolism*; D015815:Cell Adhesion Molecules / Q000096:biosynthesis*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D018613:Microscopy, Confocal; D009865:Oocytes / Q000378:metabolism*; D011247:Pregnancy
chemical_list: D015815:Cell Adhesion Molecules; C093649:TRO protein, human