title: A ferroxidase encoded by FOX1 contributes to iron assimilation under conditions of poor iron nutrition in Chlamydomonas.
abstract: When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway. Alternative pathways for iron assimilation, such as those involving ZIP family transporters IRT1 and IRT2, may be operational.
authors.affiliation: Department of Chemistry and Biochemistry, Box 951569, University of California-Los Angeles, Los Angeles, CA 90095-1569, USA.
authors.forename: Jen-Chih
authors.initials: JC
authors.lastname: Chen
authors.forename: Scott I
authors.initials: SI
authors.lastname: Hsieh
authors.forename: Janette
authors.initials: J
authors.lastname: Kropat
authors.forename: Sabeeha S
authors.initials: SS
authors.lastname: Merchant
mesh_terms: D000818:Animals; D027682:Cation Transport Proteins / Q000378:metabolism; D002570:Ceruloplasmin / Q000235:genetics / Q000378:metabolism*; D016825:Chlamydomonas reinhardtii / Q000201:enzymology / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000378:metabolism
chemical_list: D027682:Cation Transport Proteins; D026901:Membrane Transport Proteins; D007501:Iron; D002570:Ceruloplasmin