title: SAFE--the Special Non-invasive Advances in Fetal and Neonatal Evaluation Network: aims and achievements.
abstract: In this short review, the objectives and work of SAFE--the Special Non-invasive Advances in Fetal and Neonatal Evaluation Network, a European Union Framework VI network of excellence is described. We demonstrate how this network facilitates the implementation of non-invasive prenatal diagnosis (NIPD) for single gene disorders, fetal rhesus typing, aneuploidy and pregnancy complications.
authors.affiliation: Clinical and Molecular Genetics Unit, Institute of Child Health and Fetal Medicine Unit, University College London NHS Foundation Trust, London, UK. l.chitty@ich.ucl.ac.uk
authors.forename: Lyn S
authors.initials: LS
authors.lastname: Chitty
authors.forename: C Ellen
authors.initials: CE
authors.lastname: van der Schoot
authors.forename: Sinuhe
authors.initials: S
authors.lastname: Hahn
authors.forename: Neil D
authors.initials: ND
authors.lastname: Avent
mesh_terms: D004247:DNA / Q000097:blood / Q000235:genetics*; D005260:Female; D005315:Fetal Diseases / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000235:genetics*; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D012204:Rh-Hr Blood-Group System; D019849:Sex Determination Processes
chemical_list: D012204:Rh-Hr Blood-Group System; D004247:DNA