title: Chemical and genetic diversity of Ligularia vellerea in Yunnan, China.
abstract: Intra-specific diversity in Liularia vellerea growing in the northwestern to central Yunnan province of China was studied by chemical and genetic approaches. Samples collected in the Jianchuan, Lijiang, and Zhongdian areas contained 6,15-dioxygenated furanoeremophilanes as their major components (type A); whereas samples from the Luguhu area accumulated 1,6-dioxygenated furanoeremophilanes (type B); a sample from near Kunming, however, contained 6,15-dioxygenated eremophilanolides (type C). 11 beta H- and 11 alpha H-6 beta-angeloyloxy-15-carboxyeremophil-7-en-12,8-olides (eremofarfugins D and E) were also isolated and their structures were determined. A correlation between the composition and the DNA sequence was observed in the ITSs.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. tori@ph.bunri-u.ac.jp
authors.forename: Motoo
authors.initials: M
authors.lastname: Tori
authors.forename: Hiromi
authors.initials: H
authors.lastname: Nakamizo
authors.forename: Kanako
authors.initials: K
authors.lastname: Mihara
authors.forename: Masahiko
authors.initials: M
authors.lastname: Sato
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Nakashima
authors.forename: Masami
authors.initials: M
authors.lastname: Tanaka
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Saito
authors.forename: Masakazu
authors.initials: M
authors.lastname: Sono
authors.forename: Xun
authors.initials: X
authors.lastname: Gong
authors.forename: Yuemao
authors.initials: Y
authors.lastname: Shen
authors.forename: Ryo
authors.initials: R
authors.lastname: Hanai
authors.forename: Chiaki
authors.initials: C
authors.lastname: Kuroda
mesh_terms: D019659:Asteraceae / Q000737:chemistry* / Q000235:genetics*; D002681:China; D014644:Genetic Variation; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry / Q000235:genetics; D000081223:Polycyclic Sesquiterpenes; D017422:Sequence Analysis, DNA / Q000379:methods; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D013045:Species Specificity; D013237:Stereoisomerism
chemical_list: C530521:11alpha H-6 beta-angeloyloxy-15-carboxyeremophil-7-en-12,8-olide; D009281:Naphthalenes; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds