Recent advances in azasteroids chemistry.
Modified steroids have attracted a great deal of attention these last years. Their preparation is a stimulating challenge to the organic chemist, often demanding development of new and generally useful reactions. Moreover, the biological properties of modified steroids have proved to be of interest. The recent development in the partial and total syntheses of azasteroids is herein described.
Ibrahim-Ouali
Malika
M
UMR 6180 CNRS and Universite d'Aix Marseille III: Chirotechnologies: catalyse et biocatalyse, Laboratoire de Synthese Organique associe au CNRS, Faculte des Sciences et Techniques de Saint Jerome, Marseille Cedex 20, France. malika.ibrahim@univ-cezanne.fr
Rocheblave
Luc
L
D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000378:metabolism; D058891:5-alpha Reductase Inhibitors; D001378:Azasteroids / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008956:Models, Chemical; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D058891:5-alpha Reductase Inhibitors; D001378:Azasteroids; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase