title: Medicine. Sidestepping mutational meltdown.
authors.affiliation: Montreal Neurological Institute and Department of Human Genetics, McGill University, Montreal, Quebec H3A 2B4, Canada. eric@ericpc.mni.mcgill.ca
authors.forename: Eric A
authors.initials: EA
authors.lastname: Shoubridge
authors.forename: Timothy
authors.initials: T
authors.lastname: Wai
mesh_terms: D000818:Animals; D001343:Autophagy; D002460:Cell Line; D004272:DNA, Mitochondrial / Q000235:genetics*; D004259:DNA-Directed DNA Polymerase / Q000235:genetics; D003576:Electron Transport Complex IV / Q000235:genetics*; D053595:Embryonic Stem Cells; D005260:Female; D016368:Frameshift Mutation; D018095:Germ-Line Mutation; D008297:Male; D051379:Mice; D008928:Mitochondria / Q000502:physiology; D009245:NADH Dehydrogenase / Q000235:genetics*; D009865:Oocytes / Q000502:physiology*; D009866:Oogenesis; D012641:Selection, Genetic
chemical_list: D004272:DNA, Mitochondrial; D009245:NADH Dehydrogenase; C508029:NADH dehydrogenase subunit 6, mouse; D003576:Electron Transport Complex IV; C526871:cytochrome c oxidase subunit I, mouse; D004259:DNA-Directed DNA Polymerase