title: Influence of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai on the growth of algae and wood decay fungi.
abstract: Polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai act as antifouling and anticholinesterase agents. They also show moderate haemolytic and cytotoxic activities against different cell lines. The haemolytic activity of poly-APS is due to their detergent-like structure and behaviour in aqueous solutions. In this work, the lytic activity of poly-APS against freshwater and marine algae, and inhibitory effects on wood decay fungi, were investigated. The results show that poly-APS inhibit the proliferation and movements of susceptible algae. Effects of poly-APS were time- and concentration-dependent and differed between various algal species. No growth inhibition effects were observed towards the examined wood fungi.
authors.affiliation: National Institute of Biology, Ljubljana, Slovenia.
authors.forename: Tina
authors.initials: T
authors.lastname: Elersek
authors.forename: Gorazd
authors.initials: G
authors.lastname: Kosi
authors.forename: Tom
authors.initials: T
authors.lastname: Turk
authors.forename: Franc
authors.initials: F
authors.lastname: Pohleven
authors.forename: Kristina
authors.initials: K
authors.lastname: Sepcic
mesh_terms: D000818:Animals; D001487:Basidiomycota / Q000187:drug effects*; D056890:Eukaryota / Q000187:drug effects*; D005659:Fungicides, Industrial / Q000494:pharmacology; D011108:Polymers / Q000302:isolation & purification / Q000494:pharmacology*; D011161:Porifera / Q000378:metabolism*; D011726:Pyridinium Compounds / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D005659:Fungicides, Industrial; D011108:Polymers; D011726:Pyridinium Compounds; C115254:poly-APS