title: Endocrine-related reproductive effects in molluscs.
abstract: Research on endocrine disruption has been a major topic of the past decade. Although most studies concentrated on vertebrate species, invertebrates are now gaining more attention. In particular, data on molluscs is increasing. One of the best-documented and more relevant examples of endocrine disruption is the imposex phenomenon affecting some gastropod species. But the increasing interest is also due to the fact that molluscs, especially bivalves, are good bioindicators used for decades in environmental studies and that progress have been made in the understanding of the physiology and endocrinology of some mollusc species. Recent results suggest that molluscs can be adversely affected by compounds that alter their reproduction and that vertebrate-type sex-steroids metabolism or mechanism of action could be involved in these effects. Nevertheless, the endocrine system of molluscs appears to be dissimilar in many aspects to those of vertebrates and sex-steroids might not have the same importance in all mollusc species. This diversity constitutes an important opportunity to examine and understand new and alternative mechanisms for endocrine disruption.
authors.affiliation: Ecotoxicologie Marine, UR 09-03, Université de Sfax, IPEIS, BP 805, 3018 Sfax, Tunisia.
authors.forename: Imen
authors.initials: I
authors.lastname: Ketata
authors.forename: Xavier
authors.initials: X
authors.lastname: Denier
authors.forename: Amel
authors.initials: A
authors.lastname: Hamza-Chaffai
authors.forename: Christophe
authors.initials: C
authors.lastname: Minier
mesh_terms: D000818:Animals; D052244:Endocrine Disruptors / Q000633:toxicity*; D004703:Endocrine System / Q000187:drug effects* / Q000378:metabolism; D004784:Environmental Monitoring / Q000379:methods; D005260:Female; D008297:Male; D008974:Mollusca / Q000187:drug effects* / Q000378:metabolism; D012098:Reproduction / Q000187:drug effects*
chemical_list: D052244:Endocrine Disruptors