title: Verification of the Mismatch Negativity (MMN) responses in normal adult subjects.
abstract: Mismatch Negativity (MMN) is used to evaluate the central auditory system.
  
  
  OBJECTIVE
  to characterize the MMN, in normal subjects.
  
  
  METHODS
  prospective study, 12 subjects, six males and six females, between the ages of 18 and 24. "Mann-Whytnei" test. EXAMS: Pure Tone Audiometry (PTA), Tympanometry, Otoacoustic Emissions and Short and Long Latency Auditory Potentials (MMN).
  
  
  RESULTS
  in MMN variable amplitude, the mean value was of -2.757 microV and -3.548 microV, CZA1 and CZA2; of 1.435 microV and -1.867 microV, CZA1 and CZA2. In variable and medium latency, we found in 150.7ms and 153.2ms, CZA1 and CZA2; in 170.4ms and 184.0ms, CZA1 and CZA2 - for females and males respectively.
  
  
  CONCLUSIONS
  related to latency, there was significant statistical difference between the genders in relation to CZA1 and CZA2; and it was lower for females and higher for males.
authors.affiliation: Speech and Hearing Therapist.
authors.forename: Adriana
authors.initials: A
authors.lastname: Bortoleto Brossi
authors.affiliation: Speech and Hearing Therapist.
authors.forename: Karen
authors.initials: K
authors.lastname: Cristina Borba
authors.affiliation: M.S in Public Health - USP; PhD - Department of Otorhinolaryngology, Ophthalmology, Head and Neck Surgery - Medical School of Ribeirão Preto/SP-USP, Professor of Speech and Hearing Therapy - Franca - Unifran.
authors.forename: Cristiane Fregonesi
authors.initials: CF
authors.lastname: Dutra Garcia
authors.affiliation: PhD in Human Communication Disorders - UNIFESP/EPM, Professor of Speech and Hearing Therapy - Universidade de Franca - Unifran.
authors.forename: Ana Cláudia
authors.initials: AC
authors.lastname: Mirândola Barbosa Reis
authors.affiliation: PhD of Pediatrics - Medical School of Ribeirão Preto/SP - University of São Paulo, USP., ENT. Professor of Otorhinolaryngology - Department of Otorhinolaryngology, Ophthalmology and Head and Neck Surgery - Ribeirão Preto Medical School/SP -USP; Curso de Fonoaudiologia - Universidade de Franca Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço da Faculdade de Medicina de Ribeirão Preto/SP - USP.
authors.forename: Myriam de
authors.initials: M
authors.lastname: Lima Isaac
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D001301:Audiometry, Pure-Tone; D001307:Auditory Perception / Q000502:physiology*; D003430:Cross-Sectional Studies; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D011446:Prospective Studies; D012737:Sex Factors