title: Bioactive compounds of the volatile oil of Dracocephalum kotschyi.
abstract: Trypanocidal activity was found in the volatile oil of dried Dracocephalum kotschyi. GC-MS analysis determined that the major constituents of the oil were geranial (35.8%), C10H14O (26.6%), limonene (15.8%) and 1,1-dimethoxy decane (14.5%). In order to isolate the unknown biologically active monoterpene, fractionation of the volatile oil was carried out by silica gel column chromatography. The structure of the oxygenated compound was confirmed to be limonene-10-al (C10H14O) by analysis of physical and spectroscopic data (1H NMR, 13C NMR, HMBC and HMQC).
authors.affiliation: Medicinal Plants Research Center, Faculty of Pharmacy, Medical Sciences/University of Tehran, Iran. soodabehsaeidnia@hotmail.com
authors.forename: Soodabeh
authors.initials: S
authors.lastname: Saeidnia
authors.forename: Ahmad Reza
authors.initials: AR
authors.lastname: Gohari
authors.forename: Abbas
authors.initials: A
authors.lastname: Hadjiakhoondi
authors.forename: Abbas
authors.initials: A
authors.lastname: Shafiee
mesh_terms: D000080462:Acyclic Monoterpenes; D053138:Cyclohexenes / Q000032:analysis; D019686:Lamiaceae / Q000737:chemistry*; D000077222:Limonene; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification; D013729:Terpenes / Q000032:analysis*
chemical_list: D000080462:Acyclic Monoterpenes; D053138:Cyclohexenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils; D013729:Terpenes; D000077222:Limonene; C007076:citral