[A cohort study on the correlation between birth weight, simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence].
OBJECTIVE
To determine the correlation between birth weight and simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence.


METHODS
A vertical sectional survey on 193 children aged 7 - 11 years was performed in 1996. A questionnaire consisting of items on environmental factors and lifestyle, physical examination and biochemical assessment was conducted at baseline and the 9th year of follow-up.


RESULTS
The incidence of obesity and over-weight in childhood in high (6.1%) and low birth-weight group (5.6%) was higher than that in normal birth-weight group (2.8%), but did not reach statistic significance; The levels of body mass index in adolescence in high and low birth-weight group were significantly higher than that in normal birth-weight group (P = 0.002 and 0.009, respectively), and the incidence of obesity and over-weight in adolescence was significantly higher in high (33.3%) and low birth-weight group (38.9%) than that in normal birth-weight group (16.2%, P = 0.025 and 0.020, respectively). There were no significant differences in the levels of blood glucose, blood lipids and blood pressure between different birth weight groups (all, P > 0.05).


CONCLUSIONS
Intrauterine growth is linked to physical growth during childhood and adolescence. Nutritional guidance in pregnant phase may help to control the increased prevalence of overweight and obesity in children and adolescent.
Hua
Qi
Q
Department of Cardiology, Xuanwu Hospital, Capital University of Medical Science, Beijing 100053, China. huaqi5371@medmail.com.cn
Tan
Jing
J
Liu
Zhao-hui
ZH
Liu
Rong-kun
RK
Yang
Zheng
Z
D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D002648:Child; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000097:blood* / Q000453:epidemiology / Q000503:physiopathology*; D011795:Surveys and Questionnaires
D001786:Blood Glucose; D008055:Lipids