title: Association of gluten enteropathy and irritable bowel syndrome in adult Turkish population.
abstract: OBJECTIVE
  Irritable bowel syndrome is generally diagnosed according to the symptoms of the patient, and gluten enteropathy can also be presented with similar symptoms (diarrhea and/or constipation) of irritable bowel syndrome. Aimed to assess the association and the frequency of gluten enteropathy in a group of Turkish patients diagnosed as irritable bowel syndrome.
  
  
  RESULTS
  Found anti-gliadin IgA positivity only in four patients among patients with irritable bowel syndrome. However, none of these four patients had anti-endomycium positivity or any histopathological findings specific for gluten enteropathy. All these four patients had normal histology in their small bowel biopsies.
  
  
  CONCLUSIONS
  Irritable bowel syndrome is a common problem in the population, but gluten enteropathy is not associated with the vast majority of subjects with irritable bowel syndrome as expected. The need for screening gluten enteropathy among these patients is still unclear, and screening with serology only without small bowel biopsy may lead to false positive results.
authors.affiliation: Gastroenterology, Sisli etfal education and research hospital, Istanbul 80260, Turkey.
authors.forename: Kamil
authors.initials: K
authors.lastname: Ozdil
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sokmen
authors.forename: Ozdal
authors.initials: O
authors.lastname: Ersoy
authors.forename: Huseyin
authors.initials: H
authors.lastname: Demirsoy
authors.forename: Besir
authors.initials: B
authors.lastname: Kesici
authors.forename: Cetin
authors.initials: C
authors.lastname: Karaca
authors.forename: Nihat
authors.initials: N
authors.lastname: Akbayir
authors.forename: Levent
authors.initials: L
authors.lastname: Erdem
authors.forename: Canan
authors.initials: C
authors.lastname: Alkim
authors.forename: Damlanur
authors.initials: D
authors.lastname: Sakiz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002446:Celiac Disease / Q000150:complications* / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005983:Glutens; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014421:Turkey / Q000453:epidemiology
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D005983:Glutens