title: First A2-to-O renal transplantation in the 21st Century: a step in the transplantation history of Turkey.
abstract: Renal transplantation is the best treatment modality for patients with end-stage renal disease. Turkey is a country with limited cadaveric donor organ programs. Herein we have reported the first A2-to-O living donor kidney transplantation in Turkey. A 20-year-old female patient was admitted for a living related renal transplantation from her only potential donor her mother. She was blood group O and her mother was blood group A2. Three plasmapheresis sessions followed by intravenous immunoglobulin (IVIG) were performed every other day in the week prior to transplantation. Daclizumab was administered at the time of transplantation with an additional four doses every 2 weeks after the procedure. The immunsuppressive regimen included tacrolimus, mycophenolate mofetil, and prednisolone. Eight plasmapheresis sessions followed by IVIG were performed in the first 2 weeks posttransplant. Six months after transplantation, the serum creatinine was 1 mg/dL. Our experience showed that A2-to-O renal transplantation can be safely performed and may expand the pool of living kidney donors in Turkey.
authors.affiliation: Department of Nephrology, Ondokuz Mayis University School of Medicine, Samsun, Turkey. dilekmelda@yahoo.com
authors.forename: M
authors.initials: M
authors.lastname: Dilek
authors.forename: B
authors.initials: B
authors.lastname: Kocak
authors.forename: N
authors.initials: N
authors.lastname: Guler
authors.forename: Z
authors.initials: Z
authors.lastname: Adibelli
authors.forename: S
authors.initials: S
authors.lastname: Sarikaya
authors.forename: T
authors.initials: T
authors.lastname: Akpolat
mesh_terms: D000017:ABO Blood-Group System; D006650:Histocompatibility Testing; D049674:History, 21st Century; D006801:Humans; D007676:Kidney Failure, Chronic / Q000266:history / Q000601:surgery; D016030:Kidney Transplantation / Q000266:history / Q000639:trends*; D010956:Plasmapheresis; D014421:Turkey
chemical_list: D000017:ABO Blood-Group System