title: [Reconstruction of maxillary defect by prefabricated titanium mesh combined with pedicled buccal fat pad flap and bone autograft].
abstract: OBJECTIVE
  To introduce individualized 3-dimensional (3-D) reconstruction of maxillary defect by prefabricated titanium mesh combined with pedicled buccal fat pad flap (PBFPF) and bone autograft.
  
  
  METHODS
  Since May, 2001, 16 patients with maxillary defect resulted from tumor or trauma were treated. The 3-D models were created through 3-D CT and rapid prototype technique. The maxilla on the unaffected side was copied to the affected side by CAD/CAM. Then the titanium mesh was prefabricated accurately on the 3-D model. The PBFPF served as lining of the titanium mesh and the autogenous bone graft was used to reconstruct the shape and function of maxilla.
  
  
  RESULTS
  The duration of follow-up was 6 to 36 months. All the wounds healed primarily with good facial symmetry. No food reflux to nasal cavity was observed. The dentitions in 8 of 16 cases were restored with good function by removable partial denture. They could have normal diet and were articulate. Nasopharyngoscopy showed normal tissue lining of the titanium mesh 5-12 months after operation in 3 cases.
  
  
  CONCLUSIONS
  Satisfactory aesthetic and functional result can be achieved with this 3-D reconstruction method for maxilla defect. The PBFPF was insert better titanium mesh and mucous of maxilla sinus to avoid exposure of titanium mesh. The fat pad flap with blood supply promotes wound healing and helps partially restoring the function of the maxillary sinus.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, College of Medicine Zhejiang University, Hangzhou 310009, China.
authors.forename: Jun-lie
authors.initials: JL
authors.lastname: Yan
authors.forename: Guan-fu
authors.initials: GF
authors.lastname: Chen
authors.forename: Yan-ming
authors.initials: YM
authors.lastname: Liu
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Zhang
authors.forename: Song
authors.initials: S
authors.lastname: Zhao
authors.forename: Chen
authors.initials: C
authors.lastname: Jiang
authors.forename: Le
authors.initials: L
authors.lastname: Chen
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation; D002610:Cheek; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla / Q000002:abnormalities / Q000601:surgery*; D008441:Maxillary Neoplasms / Q000601:surgery; D008875:Middle Aged; D013524:Surgical Flaps; D014025:Titanium / Q000627:therapeutic use; D014182:Transplantation, Autologous; D055815:Young Adult
chemical_list: D014025:Titanium