Liver transplant in an infant with bilateral cystic neuroblastoma complicated by hepatic metastases and life-threatening consumption coagulopathy.
Here we report a patient with stage-4 bilateral cystic adrenal neuroblastomas with disseminated liver metastases and consumption coagulopathy who underwent liver transplant. Our patient was initially diagnosed with infantile hepatic hemangioendothelioma and bleeding into the adrenal glands secondary to consumption coagulopathy (Kasabach-Merritt syndrome). Liver transplant was performed as a life-saving procedure under this diagnosis. We discuss this unique patient because of the diagnostic pitfalls of this rare disease and the successful clinical outcome after LT and subsequent chemotherapy for neuroblastoma.
Haberal
Mehmet
M
Department of General Surgery and Transplantation, Baskent University, Ankara, Turkey. rektorluk@baskent-ank.edu.tr
Ozcay
Figen
F
Sevmis
Sinasi
S
Karakayali
Hamdi
H
Moray
Gokhan
G
Torgay
Adnan
A
Coskun
Mehmet
M
Demirhan
Beyhan
B
Sarialioglu
Faik
F
Arslan
Gulnaz
G
D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D000311:Adrenal Glands / Q000473:pathology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
D000970:Antineoplastic Agents