title: Effects of nasal surgery on sleep quality in obstructive sleep apnea syndrome with nasal obstruction.
abstract: BACKGROUND
  The purpose of this study was to evaluate the effects of nasal surgery on nasal resistance, sleep apnea, and sleep quality in adult male patients with obstructive sleep apnea syndrome (OSAS). A prospective study was performed in OSAS patients who underwent isolated nasal surgery in a tertiary referral center.
  
  
  METHODS
  During the 3-year study period, 49 OSAS patients suffering from symptomatic nasal obstruction/impaired nasal breathing underwent the standard polysomnography before and after surgery. Polysomnography along with measures of nasal resistance and daytime sleepiness (the Epworth sleepiness scale [ESS] scores) were reviewed also.
  
  
  RESULTS
  Surgery decreased the nasal resistance (0.55 +/- 0.37 Pa/cm(3) per second versus 0.17 +/- 0.19 Pa/cm(3) per second; p < 0.001) and ESS scores (11.7 +/- 4.1 versus 3.3 +/- 1.3; p < 0.001), without changes in the apnea-hypopnea index (AHI; 44.6 +/- 22.5 versus 42.5 +/- 22.0). Surgery increased nadir oxygen saturation (76.2 +/- 10.9% versus 78.8 +/- 8.1%; p < 0.01), shortened apnea-hypopnea duration (averaged/maximum; 33.5 +/- 7.3/61.1 +/- 46.0 versus 28.8 +/- 7.4/47.3 +/- 36.1 second; p < 0.05/p < 0.01), and improved sleep quality.
  
  
  CONCLUSIONS
  The results suggest that nasal surgery is useful for lowering nasal resistance, ameliorating sleep-disordered breathing, and improving sleep quality and daytime sleepiness in OSAS.
authors.affiliation: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan. seisay@med.nagoya-u.ac.jp
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nakata
authors.forename: Akiko
authors.initials: A
authors.lastname: Noda
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Yasuma
authors.forename: Mami
authors.initials: M
authors.lastname: Morinaga
authors.forename: Makoto
authors.initials: M
authors.lastname: Sugiura
authors.forename: Naomi
authors.initials: N
authors.lastname: Katayama
authors.forename: Mine
authors.initials: M
authors.lastname: Sawaki
authors.forename: Masaaki
authors.initials: M
authors.lastname: Teranishi
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakashima
mesh_terms: D000328:Adult; D000368:Aged; D004724:Endoscopy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D009666:Nose / Q000601:surgery*; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D017286:Polysomnography; D012189:Retrospective Studies; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome