title: Ulceration of gingival mucosa after topical application of EMLA: report of four cases.
abstract: This study reports four cases of mucosa ulceration after a 30-minute application of EMLA (0.3 g) as a topical anaesthetic in dentistry. The subjects returned the next day with a white ulceration and desquamation on the application site. EMLA cream should not be applied to the oral mucosa for 30 minutes.
authors.affiliation: Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Franz-Montan
authors.forename: J
authors.initials: J
authors.lastname: Ranali
authors.forename: J C
authors.initials: JC
authors.lastname: Ramacciato
authors.forename: E D
authors.initials: ED
authors.lastname: de Andrade
authors.forename: M C
authors.initials: MC
authors.lastname: Volpato
authors.forename: F C
authors.initials: FC
authors.lastname: Groppo
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D000077442:Lidocaine, Prilocaine Drug Combination; D009061:Mouth Mucosa / Q000187:drug effects*; D019226:Oral Ulcer / Q000139:chemically induced*; D011318:Prilocaine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000779:Anesthetics, Local; D000077442:Lidocaine, Prilocaine Drug Combination; D011318:Prilocaine; D008012:Lidocaine