Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region.
We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male individuals.
Ivanov
V P
VP
Kursk State Medical University.
Solodilova
M A
MA
Polonnikov
A V
AV
Belugin
D A
DA
Shestakov
A M
AM
Ushachev
D V
DV
Khoroshaya
I V
IV
Katargina
L N
LN
Kozhukhov
M A
MA
Kolesnikova
O E
OE
D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D012426:Russia; D053773:Transforming Growth Factor beta1 / Q000235:genetics*
D053773:Transforming Growth Factor beta1