title: [Effect of baicalin on in vivo anti-virus].
abstract: OBJECTIVE
  This study is about the in vivo antivirus effect of baicalin.
  
  
  METHODS
  Adopting in vivo experiment, we administered one group of mice 2 days before infected with influenza virus (A/FM/1/47) , while administer the other group with baicalin one day after infected, to observe the effect of baicalin in protecting and curing mice against influenza virus.
  
  
  RESULTS
  Baicalin can obviously prolong the survival time of mice infected with influenza virus (A/FM/1/47) (P <0.01), eliminate the influenza virus in lung, reduce the hemagglutination tite and infectivity in pulmo, and reverse mice's pneumonic pathological changes.
  
  
  CONCLUSIONS
  Baicalin can obviously counteract influenza virus.
authors.affiliation: Pharmacy department, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China. chuzhengyun@163.com
authors.forename: Zheng-yun
authors.initials: ZY
authors.lastname: Chu
authors.forename: Ming
authors.initials: M
authors.lastname: Chu
authors.forename: Yu
authors.initials: Y
authors.lastname: Teng
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D005419:Flavonoids / Q000302:isolation & purification / Q000627:therapeutic use*; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects*; D008168:Lung / Q000187:drug effects / Q000473:pathology / Q000821:virology; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000188:drug therapy* / Q000821:virology; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D011024:Pneumonia, Viral / Q000188:drug therapy / Q000821:virology; D011897:Random Allocation; D031364:Scutellaria baicalensis / Q000737:chemistry; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D005419:Flavonoids; C038044:baicalin