title: Clinical features, polysomnography and outcome in patients with hypnic headache.
abstract: Hypnic headache is rarely reported in Asians, and the proposed International Classification of Headache Disorders (ICHD)-2 criteria have never been field-tested. We studied 17 consecutive Taiwanese patients (M/F: 9/8, mean age at onset 69.6 years) with hypnic headache from a headache clinic. Fifteen patients (88%) reported >15 headache attack days per month. Polysomnography studies done on 11 patients recorded 12 attacks in seven patients: two during rapid eye movement (REM) sleep, three during non-REM sleep and two having both. Five of the seven patients reported their headache profile during polysomnography studies. The clinical course was mostly episodic without recurrence (n = 9, 53%), followed by relapsing/remitting (n = 5) and chronic (n = 3). The ICHD-2 criteria were not fulfilled in 35% (6/17) patients based on patient recall or 60% (3/5) patients based on direct questioning during polysomnography studies. The major reason was the presence of pulsatile rather than dull headache in our patients. Unlike previous studies, our study showed hypnic headache occurred equally in both REM and non-REM sleep, and most patients ran an episodic course.
authors.affiliation: Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan.
authors.forename: J-F
authors.initials: JF
authors.lastname: Liang
authors.forename: J-L
authors.initials: JL
authors.lastname: Fuh
authors.forename: H-Y
authors.initials: HY
authors.lastname: Yu
authors.forename: C-Y
authors.initials: CY
authors.lastname: Hsu
authors.forename: S-J
authors.initials: SJ
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D051270:Headache Disorders, Primary / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D018020:Lithium Compounds / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000379:methods; D012894:Sleep Stages; D016896:Treatment Outcome
chemical_list: D018020:Lithium Compounds