title: [Clinical value of 13N-ammonia PET in assessment of cardiac disease: meta-analysis].
abstract: The clinical value of 13N-ammonia PET is reviewed by using previously published articles with significant evidence level. This meta-analysis indicated that due to excellent myocardial blood flow images, 13N-ammonia PET permits better diagnostic accuracy of ischemic heart disease and viability assessment than myocardial perfusion SPECT. Furthermore, quantitative assessment of myocardial blood flow (MBF) in absolute units can be performed using 13N-ammonia PET. MBF measurement is a useful tool to evaluate cardiac pathophysiology and monitor therapeutic effects of cardiac disease and cardiovascular risk factors.
authors.affiliation: Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine.
authors.forename: Koichi
authors.initials: K
authors.lastname: Morita
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Inoue
authors.forename: Shozo
authors.initials: S
authors.lastname: Okamoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Hirata
authors.forename: Nagara
authors.initials: N
authors.lastname: Tamaki
mesh_terms: D000328:Adult; D000641:Ammonia; D002648:Child; D006801:Humans; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D009590:Nitrogen Radioisotopes; D049268:Positron-Emission Tomography
chemical_list: D009590:Nitrogen Radioisotopes; D000641:Ammonia