A new, simple approach to confer permanent antimicrobial properties to hydroxylated surfaces by surface functionalization.
A new, simple method to obtain ultrathin polycationic monolayers on hydroxylated surfaces is described which uses a bifunctional copolymer comprising a reactive part (trimethoxysilane) and positive charges (quaternary ammonium salts) to confer antimicrobial properties.
Bouloussa
Othman
O
Institut Curie, Laboratoire de Physicochimie, 26 rue d'Ulm, 75248 Paris Cedex 05, France.
Rondelez
Francis
F
Semetey
Vincent
V
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008567:Membranes, Artificial; D008826:Microbial Sensitivity Tests; D008856:Microscopy, Fluorescence; D015394:Molecular Structure; D011073:Polyamines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D000071228:Polyelectrolytes; D000644:Quaternary Ammonium Compounds / Q000737:chemistry* / Q000494:pharmacology; D012492:Salts / Q000737:chemistry / Q000494:pharmacology; D012821:Silanes / Q000737:chemistry* / Q000494:pharmacology; D013212:Staphylococcus epidermidis / Q000187:drug effects; D013295:Streptococcus mutans / Q000187:drug effects; D013499:Surface Properties
D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial; D011073:Polyamines; D000071228:Polyelectrolytes; D000644:Quaternary Ammonium Compounds; D012492:Salts; D012821:Silanes; C071717:trimethoxysilane