Tin-free Giese reaction and the related radical carbonylation using alkyl iodides and cyanoborohydrides.
Tin-free Giese reaction and the related radical carbonylation process proceeded efficiently in the presence of sodium cyanoborohydride and tetrabutylammonium cyanoborohydride. The reaction took place chemoselectively at the carbon-iodine bond but not at the carbon-bromine and carbon-chlorine bonds. The iodine atom transfer followed by hydride reduction of the resulting carbon-iodine bond is proposed as a possible mechanism.
Ryu
Ilhyong
I
Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. ryu@c.s.osakafu-u.ac.jp
Uehara
Shohei
S
Hirao
Hidefumi
H
Fukuyama
Takahide
T