[Effect of baicalin on in vivo anti-virus].
OBJECTIVE
This study is about the in vivo antivirus effect of baicalin.


METHODS
Adopting in vivo experiment, we administered one group of mice 2 days before infected with influenza virus (A/FM/1/47) , while administer the other group with baicalin one day after infected, to observe the effect of baicalin in protecting and curing mice against influenza virus.


RESULTS
Baicalin can obviously prolong the survival time of mice infected with influenza virus (A/FM/1/47) (P <0.01), eliminate the influenza virus in lung, reduce the hemagglutination tite and infectivity in pulmo, and reverse mice's pneumonic pathological changes.


CONCLUSIONS
Baicalin can obviously counteract influenza virus.
Chu
Zheng-yun
ZY
Pharmacy department, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China. chuzhengyun@163.com
Chu
Ming
M
Teng
Yu
Y
D000818:Animals; D000998:Antiviral Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D005419:Flavonoids / Q000302:isolation & purification / Q000627:therapeutic use*; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects*; D008168:Lung / Q000187:drug effects / Q000473:pathology / Q000821:virology; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000188:drug therapy* / Q000821:virology; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D011024:Pneumonia, Viral / Q000188:drug therapy / Q000821:virology; D011897:Random Allocation; D031364:Scutellaria baicalensis / Q000737:chemistry; D016896:Treatment Outcome
D000998:Antiviral Agents; D005419:Flavonoids; C038044:baicalin