Long-term effectiveness of antiseptic cream for recurrent epistaxis in childhood: five-year follow up of a randomised, controlled trial.
OBJECTIVE
To determine the long-term outcome for children treated for recurrent epistaxis, and to compare the efficacy of antiseptic cream treatment and nasal cautery.


METHODS
Retrospective analytical cohort study of 88 children treated for recurrent epistaxis in 2001.


METHODS
Five-year data on chlorhexidine-neomycin cream usage, nasal cautery, current epistaxis frequency and emergency room attendance was collected by telephone interview and case record review.


RESULTS
During their first clinic visit, 51 per cent of the children had been treated with cautery and cream and 35 per cent with cream alone; 14 per cent had received no treatment. Five years later, 65 per cent of these children were still having ongoing epistaxis. Those who had undergone cautery and received cream had the highest ongoing bleeding rate (77 per cent).


CONCLUSIONS
The majority of children treated at our clinic for recurrent epistaxis had ongoing bleeding five years later. Despite the proven short-term efficacy of chlorhexidine-neomycin cream, few patients receive further courses of cream or are referred back to the clinic.
Robertson
S
S
Department of Paediatric Otolaryngology, Royal Hospital for Sick Children, Glasgow, Scotland, UK. stuart@glasgow.org
Kubba
H
H
D000293:Adolescent; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002425:Cautery; D002648:Child; D002710:Chlorhexidine / Q000627:therapeutic use*; D004338:Drug Combinations; D004643:Emollients; D004844:Epistaxis / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009355:Neomycin / Q000627:therapeutic use*; D012008:Recurrence; D012189:Retrospective Studies; D016037:Single-Blind Method
D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D004643:Emollients; D009355:Neomycin; D002710:Chlorhexidine