title: Cardiac output and other hemodynamic variables in anesthetized dogs undergoing laparotomy because of abdominal neoplasia.
abstract: OBJECTIVE
  To measure cardiac output and other hemodynamic variables in anesthetized dogs undergoing laparotomy because of abdominal neoplasia.
  
  
  METHODS
  Prospective case series.
  
  
  METHODS
  8 dogs with splenic or hepatic tumors.
  
  
  METHODS
  Dogs were anesthetized and underwent abdominal laparotomy. End-tidal isoflurane concentration, heart rate, arterial blood pressures, cardiac output, arterial pH, blood gas partial pressures, PCV, and plasma total protein concentration were measured at set intervals before, during, and after surgery. Cardiac index, stroke index, and systemic vascular resistance index were calculated.
  
  
  RESULTS
  End-tidal isoflurane concentration was lowest before and after surgery. Heart rate did not change significantly throughout the anesthetic period. Arterial blood pressures and systemic vascular resistance index were highest shortly after surgery began; cardiac index and stroke volume index did not change significantly during surgery but increased significantly after surgery ended.
  
  
  CONCLUSIONS
  Results suggested that in dogs undergoing laparotomy because of abdominal neoplasia, changes in arterial blood pressures were not necessarily indicative of qualitatively similar changes in cardiac index.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
authors.forename: Ann E
authors.initials: AE
authors.lastname: Wagner
authors.forename: Yukari
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000097:blood; D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary; D001794:Blood Pressure / Q000502:physiology*; D002248:Carbon Monoxide / Q000097:blood; D002302:Cardiac Output / Q000187:drug effects; D006348:Cardiac Surgical Procedures / Q000662:veterinary; D004283:Dog Diseases / Q000601:surgery; D004285:Dogs / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D007530:Isoflurane / Q000008:administration & dosage / Q000097:blood; D007813:Laparotomy / Q000379:methods / Q000662:veterinary*; D008113:Liver Neoplasms / Q000601:surgery / Q000662:veterinary; D011184:Postoperative Period; D011446:Prospective Studies; D013160:Splenic Neoplasms / Q000601:surgery / Q000662:veterinary; D014655:Vascular Resistance / Q000187:drug effects / Q000502:physiology
chemical_list: D018685:Anesthetics, Inhalation; D002248:Carbon Monoxide; D007530:Isoflurane