Association of gluten enteropathy and irritable bowel syndrome in adult Turkish population.
OBJECTIVE
Irritable bowel syndrome is generally diagnosed according to the symptoms of the patient, and gluten enteropathy can also be presented with similar symptoms (diarrhea and/or constipation) of irritable bowel syndrome. Aimed to assess the association and the frequency of gluten enteropathy in a group of Turkish patients diagnosed as irritable bowel syndrome.


RESULTS
Found anti-gliadin IgA positivity only in four patients among patients with irritable bowel syndrome. However, none of these four patients had anti-endomycium positivity or any histopathological findings specific for gluten enteropathy. All these four patients had normal histology in their small bowel biopsies.


CONCLUSIONS
Irritable bowel syndrome is a common problem in the population, but gluten enteropathy is not associated with the vast majority of subjects with irritable bowel syndrome as expected. The need for screening gluten enteropathy among these patients is still unclear, and screening with serology only without small bowel biopsy may lead to false positive results.
Ozdil
Kamil
K
Gastroenterology, Sisli etfal education and research hospital, Istanbul 80260, Turkey.
Sokmen
Mehmet
M
Ersoy
Ozdal
O
Demirsoy
Huseyin
H
Kesici
Besir
B
Karaca
Cetin
C
Akbayir
Nihat
N
Erdem
Levent
L
Alkim
Canan
C
Sakiz
Damlanur
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002446:Celiac Disease / Q000150:complications* / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005983:Glutens; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014421:Turkey / Q000453:epidemiology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D005983:Glutens