Highly enantioselective aldol reactions catalyzed by a recyclable fluorous (S) pyrrolidine sulfonamide on water.
Fluorous (S) pyrrolidine sulfonamide serves as an efficient promoter for highly enantioselective aldol reactions of ketones and aldehydes with aromatic aldehydes on water. A notable feature of the organocatalyst is that it can be recovered from the reaction mixtures by simple fluorous solid-phase extraction and subsequently reused (up to seven cycles) without a significant loss of catalytic activity and stereoselectivity.
Zu
Liansuo
L
Department of Chemistry & Chemical Biology, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA.
Xie
Hexin
H
Li
Hao
H
Wang
Jian
J
Wang
Wei
W