Structures and evolutionary origins of plant-specific transcription factor DNA-binding domains.
Plant-specific transcription factors are classified according to DNA-binding domains (DBDs) that were believed to be distinct from those of prokaryotes or other lineages of eukaryotes. Recently, structures of the DBDs including WRKY, NAC, B3, and SBP, which comprise major families of transcription factors, were determined by NMR spectroscopy or X-ray crystallography. In this review, we summarize the recent progress of structural biology in this field, especially on their DNA-binding mechanism and structural similarity to DBDs from other kingdoms. Unexpected structural relationships, together with recent identifications of homologous sequences in a variety of genomes, indicated that majority of the "plant-specific" DBDs originated from non-plant species, and that they largely expanded along with the evolution of higher plants.
Yamasaki
Kazuhiko
K
Age Dimension Research Center, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba 305-8566, Japan. k-yamasaki@aist.go.jp
Kigawa
Takanori
T
Inoue
Makoto
M
Watanabe
Satoru
S
Tateno
Masaru
M
Seki
Motoaki
M
Shinozaki
Kazuo
K
Yokoyama
Shigeyuki
S
D001665:Binding Sites / Q000235:genetics; D018360:Crystallography, X-Ray; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics; D019143:Evolution, Molecular; D009682:Magnetic Resonance Spectroscopy; D010940:Plant Proteins / Q000737:chemistry* / Q000235:genetics; D011487:Protein Conformation; D017434:Protein Structure, Tertiary / Q000235:genetics; D014157:Transcription Factors / Q000737:chemistry* / Q000235:genetics
D004268:DNA-Binding Proteins; D010940:Plant Proteins; D014157:Transcription Factors