Peritumoral brain edema in meningiomas: correlations between magnetic resonance imaging, angiography, and pathology.
BACKGROUND
The purpose of this study was to evaluate the radiologic characteristics and pathology related to the formation of peritumoral edema in meningiomas.


METHODS
Seventy-nine patients with meningioma were examined by MRI and cerebral angiography. The predictive factors possibly related to peritumoral edema, such as patient age, sex, tumor location, tumor size, peritumoral rim (CSF cleft), shape of tumor margin, signal intensity of tumor in T2WI, pial blood supply, and pathology, were evaluated. We defined the edema-tumor volume ratio as EI and used this index to evaluate peritumoral edema.


RESULTS
Male sex (P = .009), tumor size (P = .026), signal intensity of tumor in T2WI (P = .016), atypical and malignant tumor (P = .004), and pial blood supply (P = .001) correlated with peritumoral edema on univariate analyses. However, in multivariate analyses, pial blood supply was statistically significant as a factor for peritumoral edema in meningioma (P = .029). Male sex (P = .067, P < .1) and hyperintensity in T2WI (P = .075, P < .1) might have statistical probability in peritumoral edema.


CONCLUSIONS
In our results, male sex, hyperintensity on T2WI, and pial blood supply were associated with peritumoral edema in meningioma that influence the clinical prognosis of patients.
Lee
Kyung-Jin
KJ
Department of Neurosurgery, The Catholic University of Korea, Seoul, 150-713, South Korea.
Joo
Won-Il
WI
Rha
Hyung-Kyun
HK
Park
Hae-Kwan
HK
Chough
Jung-Ki
JK
Hong
Yong-Kil
YK
Park
Chun-Keun
CK
D000328:Adult; D000368:Aged; D001929:Brain Edema / Q000209:etiology*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D008579:Meningioma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors; D047368:Tumor Burden