Minimizing variation due to genotype and environment.
Mouse models are increasingly popular tools to study and characterize the molecular and physiological bases for human diseases. Due to the readily available genetic tools to construct mouse models of complex diseases, the flow of efficient and vigilant mouse phenotyping has now become the bottleneck in mouse functional genomics. This unit addresses the importance of minimizing and defining confounding genetic and environmental sources of variability.
Argmann
Carmen A
CA
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
Auwerx
Johan
J
D000818:Animals; D019411:Clinical Laboratory Techniques; D004777:Environment; D014644:Genetic Variation; D005838:Genotype; D051379:Mice; D023421:Models, Animal; D012015:Reference Standards