title: Effects of Lactobacillus acidophilus 43121 and a mixture of Lactobacillus casei and Bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs.
abstract: The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.
authors.affiliation: Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea.
authors.forename: Yoo Heon
authors.initials: YH
authors.lastname: Park
authors.forename: Jong Gun
authors.initials: JG
authors.lastname: Kim
authors.forename: Young Won
authors.initials: YW
authors.lastname: Shin
authors.forename: Hyung Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Young-Jun
authors.initials: YJ
authors.lastname: Kim
authors.forename: Taehoon
authors.initials: T
authors.lastname: Chun
authors.forename: Sae Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Kwang Youn
authors.initials: KY
authors.lastname: Whang
mesh_terms: D000818:Animals; D001644:Bifidobacterium / Q000502:physiology*; D002784:Cholesterol / Q000097:blood*; D005243:Feces; D006937:Hypercholesterolemia / Q000097:blood / Q000378:metabolism / Q000382:microbiology*; D007779:Lactobacillus acidophilus / Q000502:physiology*; D007780:Lacticaseibacillus casei / Q000502:physiology*; D013261:Sterols / Q000378:metabolism*; D013552:Swine
chemical_list: D013261:Sterols; D002784:Cholesterol