The synthesis of unsubstituted cyclic imides using hydroxylamine under microwave irradiation.
Unsubstituted cyclic imides were synthesized from a series of cyclic anhydrides, hydroxylamine hydrochloride (NH2OH.HCl), and 4-N,N-dimethylamino-pyridine (DMAP, base catalyst) under microwave irradiation in monomode and multimode microwaves. This novel microwave synthesis produced high yields of the unsubstituted cyclic imides for both the monomode (61 - 81%) and multimode (84 - 97%) microwaves.
Benjamin
Ellis
E
Department of Chemistry and Physics, Arkansas State University, AR 72467, USA. ellisbenjamin@astate.edu
Hijji
Yousef
Y
D003500:Cyclization; D019811:Hydroxylamine / Q000737:chemistry*; D007094:Imides / Q000138:chemical synthesis*; D008872:Microwaves; D008958:Models, Molecular; D011725:Pyridines / Q000737:chemistry
C417980:4-(dimethylamine)pyridine; D007094:Imides; D011725:Pyridines; D019811:Hydroxylamine