title: [The treatment of psychotic depression in patients insufficiently responsive to conventional medication and electroconvulsive therapy; what are the options?].
abstract: Two patients with a psychotic depression showed insufficient response to pharmacotherapy and electroconvulsive therapy. The problem therefore was which alternative treatment options should be considered at this stage. On the bases of the available literature the most suitable options seemed to be clozapine, a monoamine oxidase inhibitor and lithium addition. Patient A responded well to clozapine and the condition of patient B improved during treatment with tranylcypromine, lithium and quetiapine.
authors.affiliation: Werkzaam als psychiater in opleiding in het Universitair Medisch Centrum Groningen. Hij is momenteel werkzaam als psychiater in opleiding bij de Dr. S. van Mesdagkliniek in Groningen.
authors.forename: M R
authors.initials: MR
authors.lastname: Koerhuis
authors.forename: A
authors.initials: A
authors.lastname: Wunderink
authors.forename: W A
authors.initials: WA
authors.lastname: Nolen
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003024:Clozapine / Q000627:therapeutic use; D003866:Depressive Disorder / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D018020:Lithium Compounds / Q000627:therapeutic use; D008875:Middle Aged; D011618:Psychotic Disorders / Q000628:therapy*; D013812:Therapeutics; D014191:Tranylcypromine / Q000627:therapeutic use
chemical_list: D014150:Antipsychotic Agents; D018020:Lithium Compounds; D014191:Tranylcypromine; D003024:Clozapine