title: Enriched enrolment with randomised withdrawal (EERW): Time for a new look at clinical trial design in chronic pain.
authors.affiliation: Pain Research, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK Institut Gustave-Roussy, Département de Interdisciplinaire de Soins de Support, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Laboratoires Grunenthal, 100-102 rue de Villiers, 92309 Levallois-Perret, France.
authors.forename: Henry J
authors.initials: HJ
authors.lastname: McQuay
authors.forename: Sheena
authors.initials: S
authors.lastname: Derry
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Moore
authors.forename: Philippe
authors.initials: P
authors.lastname: Poulain
authors.forename: Valérie
authors.initials: V
authors.lastname: Legout
mesh_terms: D000700:Analgesics / Q000008:administration & dosage*; D002908:Chronic Disease / Q000628:therapy; D003627:Data Interpretation, Statistical; D006801:Humans; D010148:Intractable Pain / Q000188:drug therapy* / Q000503:physiopathology* / Q000523:psychology; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000379:methods* / Q000592:standards*; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology* / Q000523:psychology; D016896:Treatment Outcome; D028761:Withholding Treatment / Q000592:standards
chemical_list: D000700:Analgesics