title: [Rehabilitation on functional amblyopia in Morning Glory Syndrome].
abstract: BACKGROUND
  Morning Glory syndrome, characterized by an enlarged dysplasic optic disc with glial tissue, is one of the congenital anomalies of the optic nerve. This syndrome is rare, prevalent in the girls, and generally unilateral. It can be revealed with nystagmus, strabismus, or amblyopia.
  
  
  METHODS
  We report the clinical observation of a 2.5-year-old girl, referred for the diagnosis of Morning Glory syndrome in the left eye with severe amblyopia (1/10 Rossano 1/20) and esotropia. This syndrome has associated central nervous system anomalies with a basal encephalocele. Treated with functional amblyopia therapy, visual acuity was 7/10 Rossano 1/2 after 1 year.
  
  
  CONCLUSIONS
  Rehabilitation on functional amblyopia in organic optic nerve anomalies is essential. A child with a Morning Glory syndrome, detected during the period of sensory maturation, must be treated with occlusion therapy, followed by maintenance treatment. This part of the treatment can prevent deep amblyopia. Moreover, regular ophthalmologic follow-up to detect complications of retinal detachment and multidisciplinary follow-up to detect a cytogenetic disease, CHARGE syndrome, or association with endocrine and central nervous system anomalies are necessary.
  
  
  CONCLUSIONS
  The author recommends occlusion therapy for children with Morning Glory syndrome or other organic asymmetric optic nerve anomalies, during the period of amblyopia reversibility. Most patients' vision improves after treatment. This case is an illustration.
authors.affiliation: Service d'ophtalmologie, Hôpital Nord, Marseille. coralielo@aol.com
authors.forename: C
authors.initials: C
authors.lastname: Loudot
authors.forename: C
authors.initials: C
authors.lastname: Fogliarini
authors.forename: C
authors.initials: C
authors.lastname: Baeteman
authors.forename: J
authors.initials: J
authors.lastname: Mancini
authors.forename: N
authors.initials: N
authors.lastname: Girard
authors.forename: D
authors.initials: D
authors.lastname: Denis
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000534:rehabilitation; D000550:Amblyopia / Q000151:congenital* / Q000175:diagnosis / Q000534:rehabilitation; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004677:Encephalocele / Q000150:complications / Q000175:diagnosis; D004948:Esotropia / Q000151:congenital* / Q000175:diagnosis / Q000534:rehabilitation; D005004:Ethmoid Bone / Q000002:abnormalities / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000002:abnormalities / Q000473:pathology; D005911:Gliosis / Q000151:congenital*; D006801:Humans; D008279:Magnetic Resonance Imaging; D020417:Nystagmus, Congenital / Q000175:diagnosis / Q000534:rehabilitation*; D009898:Optic Disk / Q000002:abnormalities*; D009900:Optic Nerve / Q000002:abnormalities*; D012683:Sensory Deprivation; D013577:Syndrome; D014792:Visual Acuity / Q000502:physiology