title: Can surgeons improve survival in stage IV melanoma?
abstract: Successful systemic management of stage IV melanoma continues to be elusive because of the paucity of effective therapies. This has fueled the continued interest in surgical resection. Several single-institution studies and a current, large, multi-institutional phase III trial have demonstrated a survival benefit for patients who underwent surgical resection for melanoma metastases. Incorporating these results into new approaches using multimodality treatment may enhance survival in patients with stage IV melanoma.
authors.affiliation: Department of Surgery, Lehigh Valley Hospital, Allentown, PA, USA.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Mosca
authors.forename: Erik
authors.initials: E
authors.lastname: Teicher
authors.forename: Suresh P
authors.initials: SP
authors.lastname: Nair
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Pockaj
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D008545:Melanoma / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery*; D020360:Neoadjuvant Therapy; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*; D016019:Survival Analysis