title: Prevalence of peptic ulcer in dyspeptic patients and the influence of age, sex, and Helicobacter pylori infection.
abstract: We investigated the prevalence of peptic ulcer in dyspeptic patients in China to analyze the influence of age, sex, and Helicobacter pylori (H. pylori) infection. The results showed that the prevalence of gastric and duodenal ulcer increased with age. In patients under 60 years old, the prevalence of duodenal and gastric ulcers in females was markedly lower than that in males, especially the prevalence of duodenal ulcer. The prevalence of duodenal ulcer and gastric ulcer in H. pylori-infected patients was markedly higher than in patients without H. pylori infection. In the patients under 60 years old, sex differences were still seen in both H. pylori-positive and H. pylori-negative patients. The prevalence of gastric and duodenal ulcers was markedly increased with age in both H. pylori-positive and H. pylori-negative patients. Multivariate logistic regression analysis showed that age, male sex, and H. pylori infection were three independent risk factors for gastric and duodenal ulcers.
authors.affiliation: Department of Gastroenterology, Affiliated Hospital, Zunyi Medical College, Zunyi, 563003, China.
authors.forename: Hui-Chao
authors.initials: HC
authors.lastname: Wu
authors.forename: Bi-Guang
authors.initials: BG
authors.lastname: Tuo
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Wu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Xu
authors.forename: Kui
authors.initials: K
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002681:China / Q000453:epidemiology; D004415:Dyspepsia / Q000150:complications*; D005260:Female; D006306:Health Surveys; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors