Assessment of risk of insect-resistant transgenic crops to nontarget arthropods.
An international initiative is developing a scientifically rigorous approach to evaluate the potential risks to nontarget arthropods (NTAs) posed by insect-resistant, genetically modified (IRGM) crops. It adapts the tiered approach to risk assessment that is used internationally within regulatory toxicology and environmental sciences. The approach focuses on the formulation and testing of clearly stated risk hypotheses, making maximum use of available data and using formal decision guidelines to progress between testing stages (or tiers). It is intended to provide guidance to regulatory agencies that are currently developing their own NTA risk assessment guidelines for IRGM crops and to help harmonize regulatory requirements between different countries and different regions of the world.
Romeis
Jörg
J
Agroscope Reckenholz-Tänikon Research Station ART, Reckenholzstr. 191, 8046 Zurich, Switzerland. joerg.romeis@art.admin.ch
Bartsch
Detlef
D
Bigler
Franz
F
Candolfi
Marco P
MP
Gielkens
Marco M C
MM
Hartley
Susan E
SE
Hellmich
Richard L
RL
Huesing
Joseph E
JE
Jepson
Paul C
PC
Layton
Raymond
R
Quemada
Hector
H
Raybould
Alan
A
Rose
Robyn I
RI
Schiemann
Joachim
J
Sears
Mark K
MK
Shelton
Anthony M
AM
Sweet
Jeremy
J
Vaituzis
Zigfridas
Z
Wolt
Jeffrey D
JD
D000818:Animals; D001181:Arthropods / Q000187:drug effects*; D001427:Bacterial Toxins / Q000235:genetics / Q000633:toxicity*; D018390:Gene Targeting / Q000379:methods; D010572:Pest Control, Biological; D030821:Plants, Genetically Modified / Q000469:parasitology / Q000633:toxicity*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors
D001427:Bacterial Toxins