title: Erythema multiforme after radiotherapy with aromatase inhibitor administration in breast-conservation treatment for breast cancer.
abstract: Generalized eruptions associated with radiotherapy such as erythema multiforme (EM), Steven-Johnson syndrome and toxic epidermal necrolysis are uncommon reactions. A few cases of generalized eruptions during and after radiotherapy have been reported with the use of anticonvulsants and anticancer drugs. However, no reports have described mucocutaneous reactions associated with radiotherapy and concurrent use of anastrozole, an aromatase inhibitor. This report describes EM occurring after radiotherapy performed during breast-conserving treatment for breast cancer in a patient who was taking oral anastrozole.
authors.affiliation: Department of Diagnostic Radiology and Radiation Oncology, Medical School, Kochi University, Nankoku, Kochi 783-8505, Japan. jm-nakakimi@kochi-u.ac.jp
authors.forename: Kimiko
authors.initials: K
authors.lastname: Nakatani
authors.forename: Masaaki
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Hironobu
authors.initials: H
authors.lastname: Ue
authors.forename: Akihito
authors.initials: A
authors.lastname: Nishioka
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Hajime
authors.initials: H
authors.lastname: Kodama
authors.forename: Shiro
authors.initials: S
authors.lastname: Sasaguri
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ogawa
mesh_terms: D000284:Administration, Oral; D000077384:Anastrozole; D047072:Aromatase Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D004892:Erythema Multiforme / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009570:Nitriles / Q000008:administration & dosage* / Q000009:adverse effects; D011878:Radiotherapy / Q000009:adverse effects*; D014230:Triazoles / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole