Leprosy reversal reaction as immune reconstitution inflammatory syndrome in patients with AIDS.
We report 2 instances in which reactional borderline leprosy manifested itself as an immune reconstitution phenomenon in patients with acquired immunodeficiency syndrome. We discuss the clinical, laboratory-based, histopathologic, and immunohistochemical characteristics of both patients. Furthermore, we review similar reports from the literature.
Batista
Mariana D
MD
Department of Dermatology, Federal University of São Paulo, São Paulo, Brazil.
Porro
Adriana M
AM
Maeda
Solange M
SM
Gomes
Elimar E
EE
Yoshioka
Márcia C N
MC
Enokihara
Mílvia M S S
MM
Tomimori
Jane
J
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000276:immunology* / Q000503:physiopathology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D015658:HIV Infections / Q000150:complications / Q000276:immunology*; D006801:Humans; D007918:Leprosy / Q000150:complications / Q000276:immunology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009166:Mycobacterium leprae / Q000276:immunology