title: Absolute configurations of isoflavan-4-ol stereoisomers.
abstract: Isoflavan-4-ol has been synthesized quantitatively from the reduction of isoflavone in the presence of Pd/C and ammonium formate under N(2) atmosphere. Isolation of cis- and trans-isomers was achieved by flash column chromatography and each enantiomer was separated by Sumi-Chiral column chromatography. Absolute configurations of four stereoisomers were determined by circular dichroism spectroscopy.
authors.affiliation: Metalloenzyme Research Group and Department of Biotechnology, Chung-Ang University, Gyeonggi, Anseong 456-756, Republic of Korea.
authors.forename: Dongho
authors.initials: D
authors.lastname: Won
authors.forename: Bok-Kyu
authors.initials: BK
authors.lastname: Shin
authors.forename: Suil
authors.initials: S
authors.lastname: Kang
authors.forename: Hor-Gil
authors.initials: HG
authors.lastname: Hur
authors.forename: Mihyang
authors.initials: M
authors.lastname: Kim
authors.forename: Jaehong
authors.initials: J
authors.lastname: Han
mesh_terms: D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D007529:Isoflavones / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
chemical_list: D007529:Isoflavones