title: Sequence-specific control of azobenzene assemblies by molecular recognition of DNA.
abstract: We investigated the molecular recognition between the amphiphile AzoAde, which is composed of azobenzene in the hydrophobic and adenine in the hydrophilic portion of the molecule, and oligonucleotides having a homogeneous base (dA30, dT30, dG30, and dC30) at the air-water interface. On the basis of the complementary base-pairing of DNA in the duplex, orderly arrangement of AzoAde on templated dT30 was examined using pi-A isotherm, UV-vis RAS, FT-IR RAS, and XPS measurements. Although there was little interaction between AzoAde and mismatched oligonucleotides (dA30, dG30, and dC30), AzoAde prepared on a dT30 subphase stoichiometrically assembled and interacted with dT30, subsequently forming a J-form assembly at the air-water interface. AFM observation of the LB films revealed the nanostructure of the J-formed AzoAde monolayer on the dT30 subphase as well as the domain structures of the H-formed monolayers on the other oligonucleotide subphases. Therefore, dT30 has a potential application as a template for assembling AzoAde at the air-water interface.
authors.affiliation: Graduate School of Science, Hokkaido University, N21W10 Kita-ku, Sapporo, Hokkaido 001-0021, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Haruta
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Matsuo
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Niikura
authors.forename: Kuniharu
authors.initials: K
authors.lastname: Ijiro
mesh_terms: D000225:Adenine / Q000737:chemistry; D000388:Air; D001391:Azo Compounds / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure; D009841:Oligonucleotides / Q000737:chemistry; D010316:Particle Size; D013499:Surface Properties; D014867:Water / Q000737:chemistry
chemical_list: D001391:Azo Compounds; D009841:Oligonucleotides; D014867:Water; D004247:DNA; C009850:azobenzene; D000225:Adenine