Fas Bim boom!
New findings by Hughes et al. (2008), Hutcheson et al. (2008), and Weant et al. (2008) highlight the roles of apoptosis regulators Bim and Fas in the contraction phase of T cell responses and reveal consequences of failure of this process.
Green
Douglas R
DR
Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. douglas.green@stjude.org
D000818:Animals; D017209:Apoptosis; D051017:Apoptosis Regulatory Proteins / Q000276:immunology / Q000378:metabolism*; D000072224:Bcl-2-Like Protein 11; D053222:Fas Ligand Protein / Q000276:immunology / Q000378:metabolism; D006801:Humans; D008213:Lymphocyte Activation; D008565:Membrane Proteins / Q000378:metabolism*; D051379:Mice; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D016176:T-Lymphocyte Subsets / Q000276:immunology* / Q000502:physiology; D019014:fas Receptor / Q000276:immunology / Q000378:metabolism*
D051017:Apoptosis Regulatory Proteins; C000606775:BCL2L11 protein, human; D000072224:Bcl-2-Like Protein 11; C000606776:Bcl2l11 protein, mouse; D053222:Fas Ligand Protein; D008565:Membrane Proteins; D011518:Proto-Oncogene Proteins; D019014:fas Receptor