title: In vitro selection of RNA aptamers to a protein target by filter immobilization.
abstract: In vitro selection of RNA aptamers that bind to a protein target is detailed in the protocols presented in this unit. Aptamers generated from these types of selection experiments can potentially function as protein inhibitors, and are often used as diagnostic or therapeutic reagents.
authors.affiliation: University of Texas, Austin, Texas, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Jhaveri
authors.forename: A D
authors.initials: AD
authors.lastname: Ellington
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000235:genetics; D018076:DNA, Complementary / Q000235:genetics; D005374:Filtration; D007202:Indicators and Reagents; D016296:Mutagenesis; D011506:Proteins / Q000235:genetics*; D012313:RNA / Q000235:genetics*; D012995:Solubility; D014158:Transcription, Genetic
chemical_list: D018076:DNA, Complementary; D007202:Indicators and Reagents; D011506:Proteins; D012313:RNA; D004247:DNA