title: Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template.
abstract: Brain registration to a stereotaxic atlas is an effective way to report anatomic locations of interest and to perform anatomic quantification. However, existing stereotaxic atlases lack comprehensive coordinate information about white matter structures. In this paper, white matter-specific atlases in stereotaxic coordinates are introduced. As a reference template, the widely used ICBM-152 was used. The atlas contains fiber orientation maps and hand-segmented white matter parcellation maps based on diffusion tensor imaging (DTI). Registration accuracy by linear and non-linear transformation was measured, and automated template-based white matter parcellation was tested. The results showed a high correlation between the manual ROI-based and the automated approaches for normal adult populations. The atlases are freely available and believed to be a useful resource as a target template and for automated parcellation methods.
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address: susumu@mri.jhu.edu.
authors.forename: Susumu
authors.initials: S
authors.lastname: Mori
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Oishi
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Hangyi
authors.initials: H
authors.lastname: Jiang
authors.affiliation: F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Li
authors.initials: L
authors.lastname: Jiang
authors.affiliation: F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Kazi
authors.initials: K
authors.lastname: Akhter
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Kegang
authors.initials: K
authors.lastname: Hua
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Andreia V
authors.initials: AV
authors.lastname: Faria
authors.affiliation: F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Asif
authors.initials: A
authors.lastname: Mahmood
authors.affiliation: UCLA Brain Mapping Center, Department of Neurology and Radiology, University of California Los Angeles, School of Medicine, Los Angeles, CA, USA.
authors.forename: Roger
authors.initials: R
authors.lastname: Woods
authors.affiliation: McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada.
authors.forename: Arthur W
authors.initials: AW
authors.lastname: Toga
authors.affiliation: Laboratory of Neuro Imaging, Department of Neurology, University of California Los Angeles, School of Medicine, Los Angeles, CA, USA.
authors.forename: G Bruce
authors.initials: GB
authors.lastname: Pike
authors.affiliation: Laboratory of Neuro Imaging, Department of Neurology, University of California Los Angeles, School of Medicine, Los Angeles, CA, USA.
authors.forename: Pedro Rosa
authors.initials: PR
authors.lastname: Neto
authors.affiliation: Laboratory of Neuro Imaging, Department of Neurology, University of California Los Angeles, School of Medicine, Los Angeles, CA, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Evans
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Jiangyang
authors.initials: J
authors.lastname: Zhang
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Michael I
authors.initials: MI
authors.lastname: Miller
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: van Zijl
authors.affiliation: UCLA Brain Mapping Center, Department of Neurology and Radiology, University of California Los Angeles, School of Medicine, Los Angeles, CA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Mazziotta
mesh_terms: D000293:Adolescent; D000328:Adult; D001271:Atlases as Topic; D001921:Brain / Q000033:anatomy & histology*; D001931:Brain Mapping; D006801:Humans; D008875:Middle Aged