title: Cell sensitivity to reaferon in patients with renal cell cancer after reaferon therapy.
abstract: Individual sensitivity of blood neutrophils to IFN-alpha2a was studied in vitro in patients with renal cell cancer before and after the first course of reaferon therapy. Cell sensitivity changed after reaferon therapy in 85% patients. This necessitates evaluation of individual cell sensitivity not only before therapy, but also before the next course of therapy.
authors.affiliation: Krasnoyarsk Territorial Oncological Center, Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk. k_shkapova@mail.ru
authors.forename: E A
authors.initials: EA
authors.lastname: Shkapova
authors.forename: L M
authors.initials: LM
authors.lastname: Kurtasova
authors.forename: A A
authors.initials: AA
authors.lastname: Savchenko
mesh_terms: D002292:Carcinoma, Renal Cell / Q000188:drug therapy*; D006801:Humans; D007370:Interferon Type I / Q000008:administration & dosage / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000494:pharmacology*; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008163:Luminescent Measurements; D009504:Neutrophils / Q000187:drug effects*; D011994:Recombinant Proteins
chemical_list: D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins