title: Testing protocols in the intensive care unit: complex trials of complex interventions for complex patients.
authors.forename: Jean-Daniel
authors.initials: JD
authors.lastname: Chiche
authors.forename: Derek C
authors.initials: DC
authors.lastname: Angus
mesh_terms: D002986:Clinical Trials as Topic; D016638:Critical Illness / Q000628:therapy*; D006801:Humans; D007362:Intensive Care Units; D011175:Positive-Pressure Respiration; D012128:Respiratory Distress Syndrome / Q000628:therapy*