Diethylene-triamine-penta-acetate administration protocol for radiological emergency medicine in nuclear fuel reprocessing plants.
Inhalation therapy of diethylene-triamine-penta-acetate (DTPA) should be initiated immediately to workers who have significant incorporation of plutonium, americium or curium in the nuclear fuel reprocessing plant. A newly designed electric mesh nebulizer is a small battery-operated passive vibrating mesh device, in which vibrations in an ultrasonic horn are used to force drug solution through a mesh of micron-sized holes. This nebulizer enables DTPA administration at an early stage in the event of a radiation emergency from contamination from the above radioactive metals.
Jin
Yutaka
Y
Japan Nuclear Fuel Limited Clinic, Aomori, Japan. yutaka.jin@jnfl.co.jp
D000280:Administration, Inhalation; D000576:Americium / Q000633:toxicity; D002614:Chelating Agents / Q000008:administration & dosage*; D002985:Clinical Protocols; D003476:Curium / Q000633:toxicity; D006801:Humans; D009330:Nebulizers and Vaporizers; D004369:Pentetic Acid / Q000008:administration & dosage*; D011005:Plutonium / Q000633:toxicity; D011210:Power Plants; D011832:Radiation Injuries / Q000188:drug therapy*; D018788:Radioactive Hazard Release; D011848:Radioactive Pollutants / Q000633:toxicity
D002614:Chelating Agents; D011848:Radioactive Pollutants; D011005:Plutonium; D004369:Pentetic Acid; D003476:Curium; D000576:Americium