title: [Survival and complications in remote period of follow-up in patients with Marfan syndrome after correction of aneurism of the ascending aorta and aortic insufficiency].
abstract: Patients with Marfan syndrome (n=44) and ascending aorta aneurism combined with aortic insufficiency were followed up for 1 month - 16 years after graft repair of the ascending aorta aneurysm and replacement of aortic valve. Patients were divided into two groups: with dissecting aneurism (n=25) and chronic nondissecting aneurism (n=19). In remote postoperative period 11 patients had 13 complications (2 patients had 2 complications each - graft dysfunction and arterial thromboembolism). Repetitive surgery was carried out in 5 patients after 67.2 +/- 19.4 months because of expansion of dissection to the abdominal aorta, dysfunction of mitral valve prosthesis. In remote period of follow up 15 patients (34.1%) died. Causes of death were graft dysfunction, extension of aortic dissection, myocardial failure. Total survival was 80, 54 and 46% for 1 month, 10 and 15 years, respectively.
authors.forename: R
authors.initials: R
authors.lastname: Cypiene
authors.forename: A
authors.initials: A
authors.lastname: Grebelis
authors.forename: P
authors.initials: P
authors.lastname: Semeniene
authors.forename: G
authors.initials: G
authors.lastname: Nogiene
mesh_terms: D001011:Aorta / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000209:etiology / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis; D016019:Survival Analysis; D016896:Treatment Outcome