title: Phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) and dusky shrew (Sorex monticolus) in the United States.
abstract: A limited search for hantaviruses in lung and liver tissues of Sorex shrews (family Soricidae, subfamily Soricinae) revealed phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) from Minnesota and in the dusky shrew (Sorex monticolus) from New Mexico and Colorado. The discovery of these shrew-borne hantaviruses, named Ash River virus and Jemez Springs virus, respectively, challenges the long-held dogma that rodents are the sole reservoir hosts and forces a re-examination of their co-evolutionary history. Also, studies now underway are aimed at clarifying the epizootiology and pathogenicity of these new members of the genus Hantavirus.
authors.affiliation: John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, Hawai'i 96813, USA.
authors.forename: Satoru
authors.initials: S
authors.lastname: Arai
authors.forename: Shannon N
authors.initials: SN
authors.lastname: Bennett
authors.forename: Laarni
authors.initials: L
authors.lastname: Sumibcay
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Cook
authors.forename: Jin-Won
authors.initials: JW
authors.lastname: Song
authors.forename: Andrew
authors.initials: A
authors.lastname: Hope
authors.forename: Cheryl
authors.initials: C
authors.lastname: Parmenter
authors.forename: Vivek R
authors.initials: VR
authors.lastname: Nerurkar
authors.forename: Terry L
authors.initials: TL
authors.lastname: Yates
authors.forename: Richard
authors.initials: R
authors.lastname: Yanagihara
mesh_terms: D000818:Animals; D004197:Disease Reservoirs / Q000821:virology; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D018778:Hantavirus Infections / Q000662:veterinary* / Q000821:virology; D008099:Liver / Q000821:virology; D008168:Lung / Q000821:virology; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D012788:Shrews / Q000821:virology*; D014481:United States