title: Proteomics and diagnostics: Let's Get Specific, again.
abstract: DNA array technology has changed all discussions about proteomics. Whole genome arrays allow unbiased experimentation, and the surprises that flow from those approaches. 'Whole proteome' proteomics is not possible today, and might never be possible unless experiments are guided by careful evaluation of reagent specificity. In this paper we explore some possible ways to increase the content of proteomic analysis.
authors.affiliation: SomaLogic, 1775 38th Street, Boulder, CO 80301, USA. dzichi@somalogic.com
authors.forename: Dom
authors.initials: D
authors.lastname: Zichi
authors.forename: Bruce
authors.initials: B
authors.lastname: Eaton
authors.forename: Britta
authors.initials: B
authors.lastname: Singer
authors.forename: Larry
authors.initials: L
authors.lastname: Gold
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology; D052158:Aptamers, Peptide / Q000378:metabolism; D003933:Diagnosis; D006801:Humans; D040081:Protein Array Analysis; D040901:Proteomics / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D000906:Antibodies; D052158:Aptamers, Peptide