Gold-catalyzed intermolecular hetero-dehydro-diels-alder cycloaddition of captodative dienynes with nitriles: a new reaction and regioselective direct access to pyridines.
For the first time, nitriles are used as 2pi electron component in a gold-catalyzed intermolecular hetero-dehydro-Diels-Alder cycloaddition with captodative enynes leading to the regioselective formation of pyridines.
Barluenga
José
J
Instituto Universitario de Química OrganometAlica "Enrique Moles", Unidad Asociada al CSIC, Universidad de Oviedo, 33006-Oviedo, Spain. barluenga@uniovi.es
Fernandez-Rodríguez
Manuel Angel
MA
García-García
Patricia
P
Aguilar
Enrique
E
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003460:Crystallization; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000480:Alkynes; D009570:Nitriles; D009942:Organometallic Compounds; D011725:Pyridines; D006046:Gold