title: Staphylococcus aureus and MRSA colonization rates among gravidas admitted to labor and delivery: a pilot study.
abstract: OBJECTIVE
  To determine colonization rates of Staphylococcus aureus given the potential for future intervention trials aimed at reducing surgical-site infectious morbidity, and to estimate methicillin-resistant Staphylococcus aureus (MRSA) rates in our patient population.
  
  
  METHODS
  Prospective pilot investigation comprising data from 104 gravidas admitted to an urban labor and delivery unit. All underwent anterior nares culture collection with a subset also undergoing vaginal culture collection.
  
  
  RESULTS
  Twenty-two percent of women were colonized in the anterior nares. Of the 28 women who had vaginal cultures collected, 4/28 (14.2%) demonstrated Staphylococcus aureus colonization. There was 82% concordance between the nares and vagina. Nine percent of isolates were MRSA strains. Overall, 2/96 (2.1%) of women were MRSA-colonized.
  
  
  CONCLUSIONS
  Rates of Staphylococcus aureus colonization among gravidas entering labor and delivery are modest and consistent with the general population. MRSA rates among gravidas appear to be reassuringly low in this pilot study.
authors.affiliation: Department of Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. rbeigi@mail.magee.edu
authors.forename: R
authors.initials: R
authors.lastname: Beigi
authors.forename: J
authors.initials: J
authors.lastname: Hanrahan
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D016106:Methicillin Resistance; D009666:Nose / Q000382:microbiology; D009820:Ohio / Q000453:epidemiology; D010865:Pilot Projects; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology*; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D014505:Urban Population; D014621:Vagina / Q000382:microbiology