title: New extensometer to measure in vivo uniaxial mechanical properties of human skin.
abstract: Biomechanical properties of skin are important for clinical decision making as well as clinical intervention. Measuring these properties in vivo is critical for estimating dimensional behaviour of skin flap or graft after harvest. However, existing methodologies and devices often suffer from lack of standardisation and unwanted peripheral force contribution due to the deformation of surrounding tissues during measurement. This naturally leads to measurement inaccuracies and lack of reproducibility. In order to improve the measurement accuracy, a new portable extensometer, which measures the non-invasive in vivo biomechanical properties of skin, has been designed and constructed. This design incorporates three pads that attach to the skin, including a C-shaped pad to shield the force sensor from peripheral forces. Such design produces data that are significantly closer to in vitro measurements. The results have been verified by finite element analysis, and experiments on rubber sheets and pig skins. This device can be used to obtain biomechanical properties of skin that will aid doctors in measuring skin elasticity and surgical planning, especially in skin flap surgery.
authors.affiliation: Digital Medicine Laboratory, National University Hospital, Singapore 119260, Singapore. Lkenghui@nus.edu.sg
authors.forename: K H
authors.initials: KH
authors.lastname: Lim
authors.forename: C M
authors.initials: CM
authors.lastname: Chew
authors.forename: P C Y
authors.initials: PC
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Jeyapalina
authors.forename: H N
authors.initials: HN
authors.lastname: Ho
authors.forename: J K
authors.initials: JK
authors.lastname: Rappel
authors.forename: B H
authors.initials: BH
authors.lastname: Lim
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena / Q000295:instrumentation* / Q000592:standards; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D012408:Rubber; D012867:Skin / Q000033:anatomy & histology*; D013314:Stress, Mechanical; D034421:Sus scrofa / Q000033:anatomy & histology; D013718:Tensile Strength / Q000502:physiology
chemical_list: D012408:Rubber