title: [Antibacterial activity and property of the fermentation product of marine Streptomyces sp. GB-2].
abstract: Marine Streptomyces GB-2, isolated from marine samples collected in the intel tidal zone of Lianyungang, was found to produce antibacterial substance which exhibited significant inhibitory effects on 11 Gram-positive bacteria and 4 Gram-negative bacteria. The antibacterial substance was proved to be neutral and water-soluble according to paper chromatogram analysis, and its production was significantly associated with aritificial seawater. The stability analysis of the fermentation broth of Streptomyces GB-2 showed that it was very stable at pH1 and pH12 under 121 degrees C and changed very little under ultraviolet treatment. The substance produced by strain GB-2 exhibited potential use in the areas of bio-control, food and medical application.
authors.affiliation: College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
authors.forename: Shu
authors.initials: S
authors.lastname: Liu
authors.forename: Ying-Jian
authors.initials: YJ
authors.lastname: Lu
authors.forename: Zhao-Xin
authors.initials: ZX
authors.lastname: Lu
authors.forename: Feng-Xia
authors.initials: FX
authors.lastname: Lü
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Bie
authors.forename: Yao-Wei
authors.initials: YW
authors.lastname: Fang
authors.forename: Zhong-Yang
authors.initials: ZY
authors.lastname: Ding
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D012623:Seawater / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents