title: [Prognostic-factor-related survival in a series of patients with renal cell carcinoma].
abstract: OBJECTIVE
  To analyze the survival rate in a series of patients with the diagnosis of renal cell carcinoma over a 19 year period based on prognostic factors usually employed in clinical practice.
  
  
  METHODS
  Retrospective study of 259 consecutive patients with the diagnosis of renal cell carcinoma undergoing surgery in our department between 1988 and 2006. From clinical, pathological, and follow-up data we performed a survival study comparing the impact of usual prognostic factors: stage, tumor size, nuclear grade, etc.
  
  
  RESULTS
  264 surgical procedures were performed in 259 patients, with a mean age of 6 1.91 yr. The most frequent way of diagnosis was incidental finding (52.12% of the cases); radical nephrectomy was performed in 72.97% of the cases in comparison with 26.25% partial nephrectomies. Clear cell carcinoma was the most frequent histological diagnosis (69.88%). Patients with clear cell carcinoma, symptomatic tumors, bigger size, and greater Fuhrman nuclear grade presented worse survivals, mainly in tumors with stage >pT3a. The presence of involved lymph nodes or distant metastases is associated with a much lower cancer-specific survival. Global five-year cancer-specific survival was over 80%.
  
  
  CONCLUSIONS
  The classical prognostic factors used to predict survival in renal cancer are still useful, mainly pathological stage pT. We observed a better survival in comparison with older series, but this kind of tumors continue generating important morbidity-mortality.
authors.affiliation: Servicio de Urología, Complejo Hospitalario Universitario de Albacete, Albacete, España. gbjosem@sescam.jccm.es
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Giménez Bachs
authors.forename: Ma José
authors.initials: MJ
authors.lastname: Donate Moreno
authors.forename: Antonio S
authors.initials: AS
authors.lastname: Salinas Sánchez
authors.forename: Héctor
authors.initials: H
authors.lastname: Pastor Navarro
authors.forename: Pedro
authors.initials: P
authors.lastname: Carrión López
authors.forename: José María
authors.initials: JM
authors.lastname: Pastor Guzmán
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Polo Ruíz
authors.forename: Mariano
authors.initials: M
authors.lastname: Martínez Martín
authors.forename: Rafael
authors.initials: R
authors.lastname: Ruíz Mondéjar
authors.forename: Julio A
authors.initials: JA
authors.lastname: Virseda Rodríguez
mesh_terms: D002292:Carcinoma, Renal Cell / Q000401:mortality* / Q000473:pathology; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate