title: [Methicillin-resistant Staphylococcus aureus-induced pyomyositis that emerged during recovery from drug-induced pancytopenia].
abstract: Pyomyositis is a purulent infection of skeletal muscle characterized by fever, localized muscle pain and stiffness, swelling and tenderness. Hematological disorder is one of the predisposing conditions for the development of pyomyositis. A 54-year-old man developed methicillin-resistant Staphylococcus aureus pyomyositis during drug-induced pancytopenia. Debridement of the infection foci combined with antimicrobial agents proved effective even in the advanced stage of the disease. In patients with hematological disorders, pyomyositis should be considered when evaluating local myalgia and high fever because this disease can be very difficult to identify and can become rapidly progressive under a myelosuppressive condition.
authors.affiliation: Division of Hematology, Department of Internal Medicine, National Defense Medical College.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Kimura
authors.forename: Kazuto
authors.initials: K
authors.lastname: Ogura
authors.forename: Ayako
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Hiroki
authors.initials: H
authors.lastname: Torikai
authors.forename: Takashi
authors.initials: T
authors.lastname: Ikeda
authors.forename: Ken
authors.initials: K
authors.lastname: Sato
authors.forename: Katsu
authors.initials: K
authors.lastname: Saionji
authors.forename: Teruyo
authors.initials: T
authors.lastname: Ito
authors.forename: Daizo
authors.initials: D
authors.lastname: Saito
authors.forename: Kazuo
authors.initials: K
authors.lastname: Motoyoshi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D010198:Pancytopenia / Q000139:chemically induced* / Q000150:complications*; D052880:Pyomyositis / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D012307:Risk Factors; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus; D016896:Treatment Outcome; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin