Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria.
Kobbe
Robin
R
Schreiber
Nadine
N
May
Jürgen
J
Jacobs
Thomas
T
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D015994:Incidence; D016779:Malaria, Cerebral / Q000188:drug therapy* / Q000453:epidemiology* / Q000469:parasitology; D051379:Mice; D008810:Mice, Inbred C57BL; D018512:Parasitemia / Q000188:drug therapy* / Q000453:epidemiology* / Q000469:parasitology; D010962:Plasmodium berghei / Q000187:drug effects*; D010963:Plasmodium falciparum; D019821:Simvastatin / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019821:Simvastatin