Green laser light (532nm) activates a chloride current in the C1 neuron of Helix aspersa.
Five hundred and thirty-two nanometers laser light evokes neuron-specific electrical responses in identified neurons of Helix ganglia. Such responses are intensity-dependent over the range 25-1500 mW, readily reversible and repeatable. Detailed experiments on the C1 neuron, which is inhibited by 532 nm light, showed that inhibition results from a selective increase in transmembrane Cl(-) ion conductance. Experiments with calcium-sensitive microelectrodes suggest that the response does not result from an increase in [Ca(2+)](i). The change in Cl(-) ion conductance probably occurs in the extensive plasmalemma infoldings of the proximal axon.
Reece
Peter J
PJ
SUPA, Department of Physics and Astronomy, University of St Andrews, KY16 9SS, UK.
Dholakia
Kishan
K
Thomas
Roger C
RC
Cottrell
Glen A
GA
D000200:Action Potentials / Q000502:physiology / Q000528:radiation effects; D000818:Animals; D001369:Axons / Q000378:metabolism / Q000528:radiation effects; D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects*; D018118:Chloride Channels / Q000378:metabolism / Q000528:radiation effects*; D002712:Chlorides / Q000378:metabolism; D017952:Ganglia, Invertebrate / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects; D006372:Helix, Snails / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D007834:Lasers; D008027:Light; D008564:Membrane Potentials / Q000502:physiology / Q000528:radiation effects; D009420:Nervous System / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D009433:Neural Inhibition / Q000502:physiology / Q000528:radiation effects; D009474:Neurons / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D010775:Photic Stimulation; D009435:Synaptic Transmission / Q000502:physiology / Q000528:radiation effects
D018118:Chloride Channels; D002712:Chlorides