Oral rehydration solution for providing water and electrolytes following laparoscopic cholecystectomy and recovery of intestinal function.
OBJECTIVE
Oral rehydration solution (OS-1: Na+ 50mEq/L, K+ 20mEq/L, Cl- 50mEq/L, and glucose 1.8%) was administered orally to patients from the early phase following laparoscopic cholecystectomy to assess its effects on water and electrolyte supplementation and recovery from postoperative intestinal paralysis.


METHODS
OS-1 group (n = 22) received OS-1 orally and KN3B group (n = 22) received KN3B (an intravenous maintenance solution) intravenously. The OS-1 group was instructed to consume approximately 1000-1500mL of OS-1 postoperatively from as soon as oral intake was possible up to before lunch on postoperative day 1.


RESULTS
The average dose in the OS-1 group (1178 +/- 319 mL) was significantly lower than that in the KN3B group (1371 +/- 196 mL), but within the target dose. The two solutions were equally effective and safe for water and electrolyte supplementation. The time for 50% of patients to pass bowel gas after surgery (indicating recovery from intestinal paralysis) was significantly shorter in the OS-1 group (14.00 hours) than in the KN3B group (23.75 hours).


CONCLUSIONS
Oral rehydration solution (OS-1), administered from the early postoperative phase, is safe and effective for the provision of water and electrolytes and promotes early recovery from intestinal paralysis as assessed by the passage of bowel gas following laparoscopic cholecystectomy.
Goseki
Narihide
N
Shuwa General Hospital, Kasukabe, Saitama, Japan. goseki@shuwa.or.jp
Hiranuma
Susumu
S
Yamazaki
Shigeru
S
Maruyama
Michio
M
Nakajima
Kazumi
K
Gen
Toukichi
T
Shirataka
Masuo
M
D000328:Adult; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006801:Humans; D007422:Intestines / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D020127:Recovery of Function; D015532:Rehydration Solutions
D015532:Rehydration Solutions