A new phenolic amide from the roots of Paris verticillata.
A new phenolic amide 8, together with the nine known phenolic compounds 1-7, 9 and 10 were isolated from the MeOH extract of the roots of Paris verticillata. The structure of the new compound 8 was determined to be 1-N-feruloylaminobutyl-4-rho-hydroxybenzamide by spectroscopic methods. The isolated compounds were tested for cytotoxicity against four human tumor cell lines using the SRB assay.
Lee
Kyu Ha
KH
Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University, Suwon 440-746, S. Korea.
Yang
Min Cheol
MC
Kim
Ki Hyun
KH
Kwon
Hak Cheol
HC
Choi
Sang Un
SU
Lee
Kang Ro
KR
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D019668:Liliaceae / Q000737:chemistry* / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry* / Q000187:drug effects
D000577:Amides; D000972:Antineoplastic Agents, Phytogenic; D010636:Phenols