Smoking cessation in clinical practice: predictors of six-month continuous abstinence in a sample of Greek smokers.
OBJECTIVE
To identify the predictors of six-month continuous abstinence among Greek smokers treated in a Smoking Cessation Clinic, emphasising the role of sleep disturbance on the outcome.


METHODS
A nested case-control design was used. Patients who attended the Smoking Cessation Clinic between November 2004 and October 2005, and who completed six months of follow-up, constituted the final study population (N=285). The patients were separated into two groups - those who managed to quit smoking and those who didn't. The cessation method included pharmacotherapy, one-to- one behavioral counselling, and follow-up by telephone communication.


RESULTS
Among various baseline characteristics examined, multivariate regression analysis indicated that the time to first cigarette after awakening, and use of bupropion, independently predicted abstinence, while awakening during the night was negatively associated with abstinence.


CONCLUSIONS
These multivariate factors, which can positively or negatively affect the outcome, should be taken into account so that smoking cessation treatment can be individualised.
Boutou
Afroditi K
AK
Respiratory Failure Unit, Aristotle University, G Papanikolaou Hospital, Thessaloniki, Greece. afboutou@yahoo.com
Tsiata
Eleni A
EA
Pataka
Athanasia
A
Kontou
Paschalina K
PK
Pitsiou
Georgia G
GG
Argyropoulou
Paraskevi
P
D000328:Adult; D016642:Bupropion / Q000627:therapeutic use*; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006115:Greece; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000009:adverse effects* / Q000627:therapeutic use; D018722:Nicotinic Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced; D012907:Smoking / Q000188:drug therapy*; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D016896:Treatment Outcome
D018722:Nicotinic Agonists; D016642:Bupropion; D009538:Nicotine