title: Hyperthyroidism-associated coronary vasospasm with myocardial infarction and subsequent euthyroid angina.
abstract: A 40-year-old African-American woman presented with atypical chest pain, an acute non-ST segment elevation myocardial infarction, and angiographic evidence for severe ostial vasospasm of the left main and right coronary arteries. Subsequently, she was diagnosed with hyperthyroidism and treated with antithyroid therapy and oral nitrates. Repeat angiography revealed resolution of the vasospasm; however, the chest pain recurred in the euthyroid state. Hyperthyroidism-associated coronary vasospasm is a rare disorder that characteristically causes angina in young Asian women and resolves with correction of hyperthyroidism. We present an atypical case of an African-American woman presenting with a myocardial infarction who developed recurrent angina while euthyroid.
authors.affiliation: Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9066, USA.
authors.forename: Rupa
authors.initials: R
authors.lastname: Patel
authors.forename: Gail
authors.initials: G
authors.lastname: Peterson
authors.forename: Anand
authors.initials: A
authors.lastname: Rohatgi
authors.forename: Hans K
authors.initials: HK
authors.lastname: Ghayee
authors.forename: Ellen C
authors.initials: EC
authors.lastname: Keeley
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Auchus
authors.forename: Alice Y
authors.initials: AY
authors.lastname: Chang
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000328:Adult; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D013956:Antithyroid Agents / Q000627:therapeutic use; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D005067:Euthyroid Sick Syndromes / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D013956:Antithyroid Agents; D014665:Vasodilator Agents