title: [Studies on chemical constituents in the buds of Tussilago farfara].
abstract: OBJECTIVE
  To study the chemical constituents in the buds of Tussilago farfara.
  
  
  METHODS
  The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.
  
  
  RESULTS
  Eleven compounds were obtained and identified as methyl 3, 4-O-dicaffeoylquinate (1), methyl 3, 5-O-dicaffeoylquinate (2), methyl 4, 5-O-dicaffeoylquinate (3), 3, 5-O-dicaffeoylquinic acid (4), methyl 3-O-caffeoylquinate (5), 3-O-caffeoylquinic acid (6), hyperoside (7), rutin (8), kaempferol 3-O-beta-D-glucopyranoside (9), quercetin (10), and kaempferol (11).
  
  
  CONCLUSIONS
  Compounds 2-5 were isolated from the genus for the first time.
authors.affiliation: Department of Natural Medicines, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
authors.forename: Yu-feng
authors.initials: YF
authors.lastname: Liu
authors.forename: Xiu-wei
authors.initials: XW
authors.lastname: Yang
authors.forename: Bin
authors.initials: B
authors.lastname: Wu
mesh_terms: D035264:Flowers / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D011801:Quinic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D012431:Rutin / Q000737:chemistry / Q000302:isolation & purification; D031207:Tussilago / Q000737:chemistry*
chemical_list: C472707:caffeoylquinic acid; C538691:methyl 3, 5-O-dicaffeoylquinate; C538692:methyl 3-O-caffeoylquinate; D011801:Quinic Acid; D012431:Rutin; C021304:hyperoside; D011794:Quercetin