title: Evaluation of sources of uncertainty in risk assessments conducted for the US Army using a case study approach.
abstract: We identify, categorize, and score sources of uncertainty in human health and ecological risk assessments conducted for several US Army sites to identify better analytical practices and opportunities for targeted research to improve risk estimates. The reviewed assessments are from reports completed within the past 8 y and were obtained from the US Army Environmental Technical Information Center (ETIC) at Aberdeen Proving Ground, Maryland, USA. Most of the risk assessments incorporated only qualitative uncertainty analysis to demonstrate the conservatism of selected data and predictive models. Food chain transfer (e.g., concentrations of contaminants across trophic levels) dominated quantifiable sources of uncertainty across the risk assessments evaluated. Factors related to dermal exposures ranked high for human health, and effects assessment for ecological endpoints.
authors.affiliation: Harvard Center for Risk Analysis, Harvard School of Public Health, 401 Park Drive, PO Box 15677, Boston, Massachusetts 02215, USA. kvon@hsph.harvard.edu
authors.forename: Katherine
authors.initials: K
authors.lastname: von Stackelberg
authors.forename: Donna
authors.initials: D
authors.lastname: Vorhees
authors.forename: Dwayne
authors.initials: D
authors.lastname: Moore
authors.forename: Jerome
authors.initials: J
authors.lastname: Cura
authors.forename: Todd
authors.initials: T
authors.lastname: Bridges
mesh_terms: D000818:Animals; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D004785:Environmental Pollutants / Q000032:analysis / Q000633:toxicity*; D056890:Eukaryota; D006801:Humans; D010944:Plants; D018570:Risk Assessment; D035501:Uncertainty; D014481:United States
chemical_list: D004785:Environmental Pollutants