Samarium(II)-mediated linker cleavage-cyclization in fluorous synthesis: reactions of samarium enolates.
SmI2 has been used to cleave a sulfur linker and trigger cyclizations in strategies for the traceless fluorous synthesis of N-heterocycles. The studies give further insights into the reactivity of samarium enolates.
James
Karen M
KM
The School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Willetts
Nigel
N
Procter
David J
DJ
D003500:Cyclization; D005461:Fluorine / Q000737:chemistry*; D012493:Samarium / Q000737:chemistry*
D005461:Fluorine; D012493:Samarium