title: Different pattern of fluid loss from the lower extremities in normohydrated and overhydrated stage 5 chronic-kidney-disease patients after haemodialysis.
abstract: OBJECTIVE
  It is unclear whether fluid is lost from each body segment in a similar manner during haemodialysis (HD) in normohydrated (NH) and overhydrated (OH) patients.
  
  
  METHODS
  The authors measured changes in regional-body fluid compartments using segmental multifrequency bioelectrical impedance analysis before and after HD in 26 stage 5 chronic-kidney-disease patients. Patients were divided into NH and OH groups. Correlation between ultrafiltration (UF) amount and per cent changes in extracellular fluid (ECF)/total body water (TBW) ratios measured in five body segments were analysed in NH and OH groups.
  
  
  RESULTS
  No differences were found between the two groups with respect to per cent decreases in body weight, TBW, or intracellular fluid levels. Correlation coefficients between UF amounts and per cent decreases in TBW, intracellular fluid and ECF were higher in the NH group than in the OH group. UF amounts were found to be correlated with per cent ECF/TBW decreases in all body segments in the NH group but, to be only correlated with per cent decreases in ECF/TBW(Left arm) and ECF/TBW(Trunk) in the OH group. Positive correlations were found between UF amounts and per cent ECF/TBW(Right leg) decreases (r = 0.66, P = 0.01), regardless of age in the NH group only.
  
  
  CONCLUSIONS
  NH and OH patients show different patterns of fluid loss from regional-body fluid compartments. This may be useful for determining patient hydration status.
authors.affiliation: Division of Nephrology and Hypertension, Department of Internal Medicine, Kidney Disease Research Group, Inha University College of Medicine, Inchon, Korea.
authors.forename: Seoung Woo
authors.initials: SW
authors.lastname: Lee
authors.forename: Geun Ho
authors.initials: GH
authors.lastname: Park
authors.forename: Seung Won
authors.initials: SW
authors.lastname: Lee
authors.forename: Wook Hyun
authors.initials: WH
authors.lastname: Um
authors.forename: Su Hyun
authors.initials: SH
authors.lastname: Kwon
authors.forename: Joon Ho
authors.initials: JH
authors.lastname: Song
authors.forename: Moon-Jae
authors.initials: MJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001823:Body Composition; D001825:Body Fluid Compartments; D001834:Body Water / Q000378:metabolism; D001835:Body Weight; D003430:Cross-Sectional Studies; D017097:Electric Impedance; D045604:Extracellular Fluid / Q000378:metabolism; D005260:Female; D017583:Hemodiafiltration; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014882:Water-Electrolyte Balance