title: Adamantane-resistant influenza infection during the 2004-05 season.
abstract: Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. We identified adamantane resistance in 47% of 152 influenza A virus (H3N2) isolates collected during 2005. Resistant and susceptible viruses caused similar symptoms and illness duration. The prevalence of resistance was highest in children.
authors.affiliation: Epidemiology Research Center (ML2), Marshfield Clinic Research Foundation, 1000 N. Oak Avenue, Marshfield, WI 54449, USA.
authors.forename: Mahbubur
authors.initials: M
authors.lastname: Rahman
authors.forename: Rick A
authors.initials: RA
authors.lastname: Bright
authors.forename: Burney A
authors.initials: BA
authors.lastname: Kieke
authors.forename: James G
authors.initials: JG
authors.lastname: Donahue
authors.forename: Robert T
authors.initials: RT
authors.lastname: Greenlee
authors.forename: Mary
authors.initials: M
authors.lastname: Vandermause
authors.forename: Amanda
authors.initials: A
authors.lastname: Balish
authors.forename: Angela
authors.initials: A
authors.lastname: Foust
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Cox
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Klimov
authors.forename: David K
authors.initials: DK
authors.lastname: Shay
authors.forename: Edward A
authors.initials: EA
authors.lastname: Belongia
mesh_terms: D000218:Adamantane / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004196:Disease Outbreaks; D024882:Drug Resistance, Viral / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D009981:Influenza B virus / Q000187:drug effects; D007251:Influenza, Human / Q000188:drug therapy* / Q000453:epidemiology / Q000235:genetics; D008297:Male; D008875:Middle Aged; D014922:Wisconsin / Q000453:epidemiology
chemical_list: D000998:Antiviral Agents; D000218:Adamantane