Dramatic improvement following interleukin 1beta blockade in tumor necrosis factor receptor-1-associated syndrome (TRAPS) resistant to anti-TNF-alpha therapy.
Sacré
Karim
K
Brihaye
Benoit
B
Lidove
Olivier
O
Papo
Thomas
T
Pocidalo
Marie-Annick
MA
Cuisset
Laurence
L
Dodé
Catherine
C
D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000235:genetics; D002097:C-Reactive Protein / Q000187:drug effects; D010505:Familial Mediterranean Fever / Q000188:drug therapy / Q000235:genetics; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D053590:Interleukin 1 Receptor Antagonist Protein / Q000627:therapeutic use*; D053583:Interleukin-1beta / Q000037:antagonists & inhibitors*; D020125:Mutation, Missense / Q000235:genetics; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000235:genetics*; D013577:Syndrome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D007155:Immunologic Factors; D053590:Interleukin 1 Receptor Antagonist Protein; D053583:Interleukin-1beta; D047888:Receptors, Tumor Necrosis Factor, Type I; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein