title: Laryngeal carcinoma in a non-smoker female patient with thyroid carcinoma: report of a case.
abstract: Laryngeal carcinoma is usually encountered in smoker men, and thyroid carcinoma is sometimes discovered incidentally during treatment for these patients. However, this coexistence of malignancies could occur in non-smoker female. We report an unusual case of multiple primary malignancies in the larynx and the thyroid gland. The laryngeal carcinoma was suspected to be related to the malignant transformation of the papillomas. The case suggests the importance of meticulous examination in the head and neck region for treatment of cervical metastatic lymph nodes with negative cytology in non-smoker female.
authors.affiliation: Department of Otorhinolaryngology, Yamato Takada Municipal Hospital, 1-1 Isonokita, Yamatotakada, Nara 635-8501, Japan. naokish@naramed-u.ac.jp
authors.forename: Naoki
authors.initials: N
authors.lastname: Shimizu
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Okamoto
authors.forename: Shinji
authors.initials: S
authors.lastname: Koyama
authors.forename: Katsunari
authors.initials: K
authors.lastname: Yane
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hosoi
authors.forename: Ryuji
authors.initials: R
authors.lastname: Okamura
mesh_terms: D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D007830:Larynx / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D010212:Papilloma / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012907:Smoking / Q000009:adverse effects; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D013965:Thyroidectomy