Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis.
Melioidosis is an infectious disease endemic to northern Australia and Southeast Asia. In response to clinical confusion regarding the appropriate dose of amoxicillin-clavulanate, we have developed guidelines for the appropriate dosing of this second-line agent. For eradication therapy for melioidosis, we recommend 20/5 mg/kg orally, three times daily.
Cheng
Allen C
AC
Department of Medicine, University of Melbourne, Melbourne, Australia. allen.cheng@menzies.edu.au
Chierakul
Wirongrong
W
Chaowagul
Wipada
W
Chetchotisakd
Ploenchan
P
Limmathurotsakul
Direk
D
Dance
David A B
DA
Peacock
Sharon J
SJ
Currie
Bart J
BJ
D000284:Administration, Oral; D000328:Adult; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002648:Child; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008554:Melioidosis / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D019980:Amoxicillin-Potassium Clavulanate Combination