title: Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region.
abstract: We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male individuals.
authors.affiliation: Kursk State Medical University.
authors.forename: V P
authors.initials: VP
authors.lastname: Ivanov
authors.forename: M A
authors.initials: MA
authors.lastname: Solodilova
authors.forename: A V
authors.initials: AV
authors.lastname: Polonnikov
authors.forename: D A
authors.initials: DA
authors.lastname: Belugin
authors.forename: A M
authors.initials: AM
authors.lastname: Shestakov
authors.forename: D V
authors.initials: DV
authors.lastname: Ushachev
authors.forename: I V
authors.initials: IV
authors.lastname: Khoroshaya
authors.forename: L N
authors.initials: LN
authors.lastname: Katargina
authors.forename: M A
authors.initials: MA
authors.lastname: Kozhukhov
authors.forename: O E
authors.initials: OE
authors.lastname: Kolesnikova
mesh_terms: D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D012426:Russia; D053773:Transforming Growth Factor beta1 / Q000235:genetics*
chemical_list: D053773:Transforming Growth Factor beta1