Homobenzotetramisole: an effective catalyst for kinetic resolution of aryl-cycloalkanols.
Homobenzotetramisole (HBTM), a ring-expanded analogue of the previously reported catalyst BTM, displays higher catalytic activity and a different structure-selectivity profile. It displays good enantioselectivities in kinetic resolution of secondary benzylic alcohols but is particularly effective for 2-aryl-substituted cycloalkanols.
Birman
Vladimir B
VB
Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, MO 63130, USA. birman@wustl.edu
Li
Ximin
X
D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D007700:Kinetics; D013329:Structure-Activity Relationship; D013696:Temperature; D013773:Tetramisole / Q000031:analogs & derivatives* / Q000737:chemistry
D000473:Alkanes; C515434:benzotetramisole; D013773:Tetramisole