Prognostic factors in the treatment of squamous cell carcinoma of the larynx: partial surgery x radical surgery.
The present study aimed at assessing the other sites as the carcinoma spreads, as well as therapeutic results, in larynx preservation and patient survival.


METHODS
It is a Longitudinal Historical Cohort Study, a retrospective clinical study.


METHODS
A hundred and sixty (160) patients treated at Escola Paulista de Medicina (Paulista Medical School) - São Paulo Hospital, from January 1988 to December 2004 were examined as for the spreading of their larynx carcinoma. Those patients whose evaluations were at least two years old after treatment were the only ones accepted. The parametric tests used were: Test X2, Fishers test, and Kaplan-Meiers curve.


RESULTS
The posterior commissure and the infraglottis were significant in terms of the laryngectomy: glottal tumors AC: (p=0.03) AP: (p=0.0001); AC: (p=0.0007) AP: (p<0.0001), respectively. The infraglottis was significant in G+SG tumors in AP: (p=0.04) and in death rate AP: (p=0.03).


CONCLUSIONS
total laryngectomy is the treatment of choice in the presence of total involvement of the posterior commissure and the infraglottis. The latter may compromise survival, according to local invasion, even in the presence of free surgical margins.
Graça Caminha Vidal
Maria da
MD
Graduate student from the Escola Paulista de Medicina SP, Head of the SCCP - Hospital da Universidade Federal de Santa Maria - RS.
Cervantes
Onivaldo
O
Professor of the Head and Neck Surgery Department /Otorhinolaryngology of the Escola Paulista de Medicina de São Paulo, Head of the SCCP of the Escola Paulista de Medicina - SP.
Abrah Ão
Marcio
M
Professor of the Head and Neck Surgery Department /Otorhinolaryngology of the Escola Paulista de Medicina de São Paulo, Head physician of the SCCP of the Escola Paulista de Medicina - SP.
Carneiro Hojaij
Flávio
F
PhD in Head and Neck Surgery from the Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo, Assistant Physician of the SCCP of the Escola Paulista de Medicina.
Amar
Ali
A
PhD in Head and Neck Surgery from the Escola Paulista de Medicina de São Paulo, Assistant Physician at the Hospital Heliópolis São Paulo.
D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome