title: The quality of DNA extracted from liquid or dried blood is not adversely affected by storage at 4 degrees C for up to 24 h.
abstract: BACKGROUND
  A consistent and stable source of DNA is an essential requirement for many Biobanks. An important pre-analytical variable is the delay between sample collection and sample processing.
  
  
  METHODS
  Fresh blood samples (n = 80) were collected and either processed immediately or after storage for 24 h. The samples were either stored as liquid blood at 4 degrees C or as dried blood spots at ambient temperature on three types of paper-based storage media. The quality of the DNA extracted from the samples was measured.
  
  
  RESULTS
  No difference was observed between fresh and stored blood samples.
  
  
  CONCLUSIONS
  The quality of DNA extracted from liquid or dried blood is not adversely affected by storage at 4 degrees C for up to 24 h.
authors.affiliation: Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester M1 7DN, UK.
authors.forename: Antony
authors.initials: A
authors.lastname: Halsall
authors.forename: Paul
authors.initials: P
authors.lastname: Ravetto
authors.forename: Yancy
authors.initials: Y
authors.lastname: Reyes
authors.forename: Nicola
authors.initials: N
authors.lastname: Thelwell
authors.forename: Alice
authors.initials: A
authors.lastname: Davidson
authors.forename: Rupert
authors.initials: R
authors.lastname: Gaut
authors.forename: Stephen
authors.initials: S
authors.lastname: Little
mesh_terms: D001771:Blood Banks; D001793:Blood Preservation / Q000379:methods* / Q000592:standards; D001800:Blood Specimen Collection / Q000379:methods / Q000592:standards; D004247:DNA / Q000097:blood*; D006801:Humans; D017410:Practice Guidelines as Topic; D011786:Quality Control; D013696:Temperature; D013997:Time Factors; D006113:United Kingdom
chemical_list: D004247:DNA