[Advance in differentiation of embryonic stem cells into osteoblasts in vitro].
OBJECTIVE
To review the progress, methods and obstacles in the differentiation of embryonic stem cells (ESCs) into osteoblasts in vitro.


METHODS
The recent literature concerned with the differentiation of ESCs into the osteoblasts was extensively reviewed and briefly summarized.


RESULTS
ESCs was a good tool for derivation of obsteoblasts.


CONCLUSIONS
The study on the induction of ESCs into the osteogenic lineage provides a model for analyzing the molecular processes of osteoblasts development in vivo and establishes the foundation for the use of ESCs in skeletal tissue repair.
Sun
Yadong
Y
Vocation College of Shenyang Agriculture University, Shenyang Liaoning, 110122, PR China. sydlsh@163.com
Zhang
Hongyu
H
Hua
Jinlian
J
D000818:Animals; D018929:Cell Culture Techniques / Q000379:methods; D002454:Cell Differentiation; D049109:Cell Proliferation; D002478:Cells, Cultured; D018920:Coculture Techniques; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D051379:Mice; D010006:Osteoblasts / Q000166:cytology* / Q000502:physiology; D010012:Osteogenesis; D023822:Tissue Engineering / Q000379:methods*