Insecticidal activity of major lichen compounds, (-)- and (+)-usnic acid, against the larvae of house mosquito, Culex pipiens L.
In this research, (-)-usnic acid and (+)-usnic acid, commonly encountered lichen secondary metabolites, were evaluated for their insecticidal effects against the larvae of Culex pipiens L. (Diptera: Culicidae) under laboratory conditions. Both compounds showed strong larvicidal activity and caused 100% mortality on third-fourth larval stages of the species at 24 h at the doses of 5 and 10 ppm. Bioassays with (-)- and (+)-usnic acids against larvae of C. pipiens revealed that the LC50 values were 0.8 and 0.9 ppm, respectively. The results suggest that lichen compounds could be useful in the search of new insecticides.
Cetin
Huseyin
H
Department of Biology, Faculty of Arts and Science, Akdeniz University, 07070 Antalya, Turkey. hcetin@akdeniz.edu.tr
Tufan-Cetin
Ozge
O
Turk
Ayse Ozdemir
AO
Tay
Turgay
T
Candan
Mehmet
M
Yanikoglu
Atila
A
Sumbul
Huseyin
H
D000818:Animals; D001572:Benzofurans / Q000494:pharmacology*; D003465:Culex / Q000187:drug effects*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D008011:Lichens / Q000737:chemistry*; D015394:Molecular Structure; D016019:Survival Analysis
D001572:Benzofurans; D007306:Insecticides; C073339:usnic acid