[Revascularization of the myocardium in patients with ischemic heart disease. Experience of the use of sirolimus eluting stents].
The author presented a review of clinical research works conducted and completed in 2001 - 2005. The review contains data on clinical trials of sirolimus-eluting stents in patients with coronary artery disease. The author analyzed experimental data on the mechanism of action of rapamycin on the cell and also analyzed data of clinical trials of sirolimus-containing stents in the treatment of coronary artery stenosis and chronic occlusion. Results of clinical trials of coated stents in diabetic patients with coronary artery stenosis, as well as data on the use sirolimus-containing stents in the treatment in stent restenosis were also discussed.
Maslov
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D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000628:therapy; D023921:Coronary Stenosis / Q000628:therapy; D054855:Drug-Eluting Stents; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D020123:Sirolimus / Q000627:therapeutic use*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D002317:Cardiovascular Agents; D007166:Immunosuppressive Agents; D020123:Sirolimus