title: PID-ARI.net - a pediatric infectious diseases network on acute respiratory infections and the added value of a multilevel research network.
abstract: BACKGROUND
  PID-ARI.net was one of three infectious disease epidemiological research networks funded by the German Ministry of Education and Research (BMBF). Its objectives were to strengthen the national initiative on infectious diseases epidemiology and to focus on a health care problem of high relevance.
  
  
  METHODS
  A research network on the epidemiology of ARI in children was formed to generate data on several levels. Key structure was a centrally organized active surveillance system in three areas of Germany from north to south.
  
  
  RESULTS
  In the 6 years of funding by the BMBF, an integrated research network with a known population denominator was formed. In the laboratory-based surveillance of up to 19 respiratory pathogens, 18,899 samples were analyzed. The added value is utilization of data on time, place, person and pathogen of a disease episode at several levels - from surveillance and online publication via a website to descriptive, analytical and molecular epidemiology and further specialized projects. Its wide age range including children up to 16 years of age, an extensive panel of pathogens, a known population denominator and the diversity of 3 distant geographical areas should considerably reduce vulnerability due to bias.
  
  
  CONCLUSIONS
  Active surveillance systems for ARI are superior to passive systems. If a surveillance system such as the one used in PID-ARI.net is part of a research network which can utilize the data on several levels, the expenditure for such a system should be worthwhile and such a system would be an asset to any health care system.
authors.affiliation: Pädiatrische Infektiologie, Klinik für Allgemeine Pädiatrie, Christian Albrecht Universität Kiel. weigl@pediatrics.uni-kiel.de
authors.forename: J A I
authors.initials: JA
authors.lastname: Weigl
authors.forename: W
authors.initials: W
authors.lastname: Puppe
authors.forename: C U
authors.initials: CU
authors.lastname: Meyer
authors.forename: R
authors.initials: R
authors.lastname: Berner
authors.forename: J
authors.initials: J
authors.lastname: Forster
authors.forename: H J
authors.initials: HJ
authors.lastname: Schmitt
authors.forename: F
authors.initials: F
authors.lastname: Zepp
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D035843:Biomedical Research; D002648:Child; D002675:Child, Preschool; D019992:Databases as Topic; D005858:Germany; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009862:Online Systems; D011159:Population Surveillance; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D011795:Surveys and Questionnaires