Detection of type 2 herpes simplex virus in cells of spermatogenic epithelium in infected testes of guinea pigs.
We developed a model of herpetic orchitis in guinea pigs. Intratesticular inoculation of type 2 herpes simplex virus suspension results in infection of the testicular spermatocytes and spermatides. The possibility of viral infection dissemination from infected into intact testis is proven.
Gribencha
S V
SV
D. I. Ivanovskii Institute of Virology, Russian Academy of Medical Sciences, Moscow.
Bragina
E E
EE
Abdumalikov
R A
RA
Bocharova
E N
EN
Kurilo
L F
LF
D000818:Animals; D006168:Guinea Pigs; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D008297:Male; D009920:Orchitis / Q000473:pathology / Q000821:virology*; D012670:Seminiferous Epithelium / Q000821:virology*