title: OCT findings in macular hole formation in eyes with complete vitreofoveal separation.
abstract: The current study describes the morphologic macular features in two eyes that developed full-thickness macular holes in the setting of documented vitreofoveal separation. Using third-generation optical coherence tomography, complete vitreofoveal separation associated with the disruption of the inner foveal retina was documented in both cases. Five months after presentation, decreased vision and epiretinal membrane formation associated with development of a full-thickness macular hole were observed in the first patient. In the second patient, a full-thickness macular hole was demonstrated by optical coherence tomography 6 weeks after presentation. These findings suggest that full-thickness macular holes may develop in eyes with vitreofoveal separation. Evidence of the disturbance of the inner foveal architecture on optical coherence tomography indicates the potential role of factors other than anteroposterior or oblique vitreoretinal tractional forces in the genesis of some full-thickness macular holes.
authors.affiliation: Centro Avancado de Retina e Catarata, Fortaleza, CE, Brazil.
authors.forename: Abelardo
authors.initials: A
authors.lastname: Targino
authors.forename: Rogério A
authors.initials: RA
authors.lastname: Costa
authors.forename: Daniela
authors.initials: D
authors.lastname: Calucci
authors.forename: José A
authors.initials: JA
authors.lastname: Cardillo
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Jorge
authors.forename: Ingrid U
authors.initials: IU
authors.lastname: Scott
mesh_terms: D000328:Adult; D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D020255:Vitreous Detachment / Q000150:complications / Q000175:diagnosis*