title: [Effects of acupuncture at different Shichen (traditional twelve two-hour periods) on serum SOD and MDA in guinea pigs].
abstract: OBJECTIVE To compare anti-oxidative effects of acupuncture at different Shichen (traditional twelve two-hour periods) accordin-17:00), You (17:00-19:00), Xu (19:00-21:00), Hui (21:00-23:00) periods according to the eight methods of the intelligent turtle, once each day, for 7 consecutive days. Changes of malondialdehyde (MDA) content and superoxide dismutase (SOD) activity after treatment were observed.
  
  
  RESULTS
  SOD activities and MDA contents at the 12 periods were different in the healthy guinea pigs, SOD activity at Wu period was the highest and the lowest at Zi period; MDA content was the highest at Zi period and the lowest at Wu period. The needling method according to eight methods of the intelligent turtle could increase SOD activity in the guinea pigs. The increasing amplitude of SOD activity was the largest at Mao period and the smallest at the Wu period; it also could decreased MDA content, the decreasing amplitude of MDA was the largest at Wu period and the smallest at Hai period.
  
  
  CONCLUSIONS
  Acupuncture at different periods according to eight methods of intelligent turtle has different effects on serum SOD and MDA, which can increase SOD activity and decrease MDA content in the healthy guinea pig.
authors.affiliation: Research Institute of Acupuncture and Moxibustion, Guangxi College of TCM, Nanning 530001, China.
authors.forename: Gan-Gong
authors.initials: GG
authors.lastname: Xie
authors.forename: Cai-Jiao
authors.initials: CJ
authors.lastname: Zhao
authors.forename: Xian-Qun
authors.initials: XQ
authors.lastname: Lu
authors.forename: Yu-Shan
authors.initials: YS
authors.lastname: Fan
authors.forename: Jian-Wen
authors.initials: JW
authors.lastname: Wu
authors.forename: Sheng
authors.initials: S
authors.lastname: Wen
mesh_terms: D015670:Acupuncture Therapy; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D013482:Superoxide Dismutase / Q000097:blood*; D013997:Time Factors
chemical_list: D008315:Malondialdehyde; D013482:Superoxide Dismutase