[A preliminary study of serum free testosterone and testosterone secreting index in men with erectile dysfunction].
OBJECTIVE
To observe the changes of serum free testosterone (FT) and testosterone secreting index (TSI) in ED patients, and to assess the contribution of these two indexes to the diagnosis of ED caused by endocrine factors.


METHODS
We studied 120 ED patients and 30 healthy men undergoing pre-marital medical check-up in Jiangsu Province Hospital of TCM by analyzing the scores on erectile function and desire domain in IIEF, testing the serum total testosterone, luteinizing hormone by chemiluminescent enzyme immunoassay (CLIA), measuring free testosterone by radioimmunoassay( RIA), and calculating TSI.


RESULTS
Of the 120 ED patients, 5% and 1538% were below the reference norm of TT and FT values respectively. TT, FT and TSI decreased with age, with statistical with FT and TSI, but not with TT. FT and TSI statistically declined with lower IIEF score on ED domain, but this was not the case with TT. There were no significant differences in TI, FT and TSI among different sexual desire groups the ED patients.


CONCLUSIONS
FT is much more valuable than TF in the diagnosis of ED with hypogonadism. Both FT and TSI are important parameters in assessing the severity of ED.
Xue
Jian-Guo
JG
Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China. Xuejg5199@126.com
Lu
Zong-Lin
ZL
Ning
Ke-Qin
KQ
He
Ying
Y
Ni
Liang-Yu
LY
Wang
Qing
Q
Huang
Jian
J
Sun
Zhi-Xing
ZX
Huang
Xin-Fei
XF
She
Yong-Qin
YQ
Ge
Liang
L
Zhang
Chun-Bing
CB
D000328:Adult; D000368:Aged; D002681:China; D007172:Erectile Dysfunction / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000097:blood* / Q000378:metabolism
D013739:Testosterone; D007986:Luteinizing Hormone