Hepatectomy for metastatic liver tumor in patients with liver dysfunction.
OBJECTIVE
In the present study, we evaluated the safety and long-term outcome of liver resection for metastatic liver tumor in patients with liver dysfunction.


METHODS
Sixty-one patients, who underwent liver resection for metastatic liver tumor, were retrospectively divided into two groups, based on the retention rate of indocyanine green at 15 minutes (ICGR15). Group 1: ICGR15 < 10% (n = 34), Group 2: ICG R15 > 10% (n = 27). Patient background, perioperative data (operation time, blood loss, duration of Pringle's maneuver, volume of resected liver), duration of postoperative hospital stay, and three-year survival rate were compared between the two groups. All data were expressed as median values.


RESULTS
There were no differences in patient backgrounds between the two groups. No significant differences were observed betweens Group 1 and 2 for operation time (383.5 vs. 345.0 min), blood loss (390 vs. 296mL), duration of Pringle's maneuver (55 vs. 42 min), volume of resected liver (402.5 vs. 110.0 mL), or duration of postoperative hospital stay (26 vs. 26 days). The three-year survival rates in Groups 1 and 2 were 72.9% and 87.8%, respectively (p = 0.937).


CONCLUSIONS
Liver resection for metastatic liver tumor in patients with liver dysfunction can be performed safely, and the long-term outcome is comparable to that in patients with normal function.
Sawada
Tokihiko
T
Second Department of Surgery, Dokkyo University School of Medicine, Tochigi, Japan. tsawada@dokkyomed.ac.jp
Kita
Junji
J
Nagata
Hitoshi
H
Shimoda
Mitsugi
M
Kubota
Keiichi
K
D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome