title: Effect of sepsis therapies on health-related quality of life.
abstract: Sepsis is one of the most common conditions encountered in the intensive care unit and is the 10th leading cause of death overall in the United States. Both long-term survival and health-related quality of life are reduced in survivors of sepsis, yet there is little knowledge of the effect of sepsis-specific interventions on either long-term survival or health-related quality of life. The present article discusses the importance of studying health-related quality of life as it relates to sepsis management strategies, particularly in the context of pharmacologic therapy with recombinant human activated protein C.
authors.forename: Sara E
authors.initials: SE
authors.lastname: Erickson
authors.forename: Greg S
authors.initials: GS
authors.lastname: Martin
mesh_terms: D018806:APACHE; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D006801:Humans; D011486:Protein C / Q000627:therapeutic use*; D011788:Quality of Life; D011994:Recombinant Proteins / Q000627:therapeutic use; D018805:Sepsis / Q000145:classification / Q000188:drug therapy* / Q000401:mortality; D015996:Survival Rate
chemical_list: D000890:Anti-Infective Agents; D011486:Protein C; D011994:Recombinant Proteins; C421124:drotrecogin alfa activated