title: Phenotypic peculiarities of batumin-resistant staphylococci.
abstract: Batumin-resistant variants of two clinical strains of Staphylococcus (S.) aureus and of strain ATCC 6538 P (209 P) were produced in vitro by continuous subculture in the presence of batumin. Their phenotypic characteristics differed substantially from the parent strains properties and did not correspond to those of S. aureus or of the genus Staphylococcus, since the colonies were small and colourless and not haemolytic, since the cells did not produce phosphatase, catalase, lecithinase, coagulase and acid from some carbohydrates and since the thickness of the cell wall and the cellular fatty acid composition were altered. On the other hand, tRNA-intergenic length polymorphism analysis and amplification of the femB gene confirmed an identification as S. aureus and AFLP-analysis and mecA gene amplification did not reveal genetic differences between batumin-susceptible and resistant strains.
authors.affiliation: Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
authors.forename: Larisa
authors.initials: L
authors.lastname: Churkina
authors.forename: Zinaida
authors.initials: Z
authors.lastname: Vasyurenko
authors.forename: Svetlana
authors.initials: S
authors.lastname: Bidnenko
authors.forename: Mario
authors.initials: M
authors.lastname: Vaneechoutte
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects*; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D009930:Organic Chemicals / Q000494:pharmacology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D009930:Organic Chemicals; C088306:batumin