title: BrainProfileDB - a platform for integration of functional genomics data.
abstract: BrainProfileDB is a database system for integrating large sets of high throughput functional genomics data of the Human Brain Proteome Project (HBPP). Within HBPP (http://www.smp-proteomics.de/) the molecular pathology of neurodegenerative diseases is investigated, using complementary methods from transcriptomics, proteomics, toponomics and interaction measurements. Aim of the database system is to provide a broad spectrum of scientific users joined in the consortium with a practical integrated view on their data. Employing appropriate mapping techniques and levels of data representation the user is relieved from technical details of gene identification or experimental measurement technique.
authors.affiliation: MicroDiscovery GmbH, Berlin, Germany. johannes.schuchhardt@microdiscovery.de
authors.forename: Johannes
authors.initials: J
authors.lastname: Schuchhardt
authors.forename: Alexander
authors.initials: A
authors.lastname: Glintschert
authors.forename: Daniela
authors.initials: D
authors.lastname: Hartl
authors.forename: Martin
authors.initials: M
authors.lastname: Irmler
authors.forename: Johannes
authors.initials: J
authors.lastname: Beckers
authors.forename: Christian
authors.initials: C
authors.lastname: Stephan
authors.forename: Katrin
authors.initials: K
authors.lastname: Marcus
authors.forename: Joachim
authors.initials: J
authors.lastname: Klose
authors.forename: Helmut E
authors.initials: HE
authors.lastname: Meyer
authors.forename: Arif
authors.initials: A
authors.lastname: Malik
mesh_terms: D001921:Brain / Q000378:metabolism*; D019295:Computational Biology / Q000379:methods; D003628:Database Management Systems; D030541:Databases, Genetic; D023281:Genomics / Q000379:methods*; D006801:Humans; D019636:Neurodegenerative Diseases / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D020543:Proteome / Q000032:analysis* / Q000235:genetics; D040901:Proteomics / Q000379:methods*
chemical_list: D020543:Proteome