title: Liver transplant in an infant with bilateral cystic neuroblastoma complicated by hepatic metastases and life-threatening consumption coagulopathy.
abstract: Here we report a patient with stage-4 bilateral cystic adrenal neuroblastomas with disseminated liver metastases and consumption coagulopathy who underwent liver transplant. Our patient was initially diagnosed with infantile hepatic hemangioendothelioma and bleeding into the adrenal glands secondary to consumption coagulopathy (Kasabach-Merritt syndrome). Liver transplant was performed as a life-saving procedure under this diagnosis. We discuss this unique patient because of the diagnostic pitfalls of this rare disease and the successful clinical outcome after LT and subsequent chemotherapy for neuroblastoma.
authors.affiliation: Department of General Surgery and Transplantation, Baskent University, Ankara, Turkey. rektorluk@baskent-ank.edu.tr
authors.forename: Mehmet
authors.initials: M
authors.lastname: Haberal
authors.forename: Figen
authors.initials: F
authors.lastname: Ozcay
authors.forename: Sinasi
authors.initials: S
authors.lastname: Sevmis
authors.forename: Hamdi
authors.initials: H
authors.lastname: Karakayali
authors.forename: Gokhan
authors.initials: G
authors.lastname: Moray
authors.forename: Adnan
authors.initials: A
authors.lastname: Torgay
authors.forename: Mehmet
authors.initials: M
authors.lastname: Coskun
authors.forename: Beyhan
authors.initials: B
authors.lastname: Demirhan
authors.forename: Faik
authors.initials: F
authors.lastname: Sarialioglu
authors.forename: Gulnaz
authors.initials: G
authors.lastname: Arslan
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D000311:Adrenal Glands / Q000473:pathology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents