title: Neural granular cell tumor. A case report.
abstract: It is presented the case of an old female with a solitary tumor at the level of the thorax. The specimen was processed using the routine histological technique and slides were stained with conventional morphologic, histochemical and immunohistochemical methods. On Hematoxylin-Eosin stained slides were noticed large cells with acidophilic cytoplasm, with granular pattern. S100 protein was intensely expressed in all tumor cells and neuron specific enolase was moderate positive. CD68 positive reaction was considered the expression of lysosomes accumulation in the cytoplasm of tumor cells. Histological and immunohistochemical findings are consistent with the diagnosis of neural granular cell tumor.
authors.affiliation: Department of Histology and Cytology, Victor Babeş University of Medicine and Pharmacy, Timisoara, Romania. cristian_suciu@yahoo.com
authors.forename: C
authors.initials: C
authors.lastname: Suciu
authors.forename: Anca Maria
authors.initials: AM
authors.lastname: Cîmpean
authors.forename: M
authors.initials: M
authors.lastname: Raica
mesh_terms: D000368:Aged; D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D006801:Humans; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D013909:Thorax / Q000473:pathology
chemical_list: D009418:S100 Proteins