title: The complete CDS of the prion protein (PRNP) gene of African lion (Panthera leo).
abstract: We provide the complete PRNP CDS sequence for the African lion, which is different from the previously published sequence and more similar to other carnivore sequences. The newly obtained prion protein sequence differs from the domestic cat sequence at three amino acid positions and contains only four octapeptide repeats. We recommend that this sequence be used as the reference sequence for future studies of the PRNP gene for this species.
authors.affiliation: Center for the Conservation of Biological Resources, Black Hills State University, 1200 University Street Unit 9053, Spearfish, SD 57799, USA.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Maj
authors.forename: Garth M
authors.initials: GM
authors.lastname: Spellman
authors.forename: Shane K
authors.initials: SK
authors.lastname: Sarver
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005796:Genes; D008045:Lions / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D011328:Prions / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment
chemical_list: D011328:Prions