Animal models of renal disease.
Mice have become a favored species to model disease. Many mouse strains have proven relatively resistant to some manipulations that have generated renal disease in other species. Kirchhoff et al. describe a means of producing hypertension, proteinuria, and glomerular sclerosis in a mouse strain.
Susztak
K
K
Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Bitzer
M
M
Meyer
T W
TW
Hostetter
T H
TH
D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics* / Q000503:physiopathology*; D051379:Mice; D008815:Mice, Inbred Strains