Polymer-assisted dithane hydrolysis with minimum workup.
The first solid-phase-assisted protocol for the hydrolysis of dithioacetals is described using three different functionalized ion exchange resins. The hydrolysis and the purification proceed under milder conditions than common homogeneously employed reagents so that very reactive carbonyl compounds can be prepared.
Luiken
Silke
S
Institut für Organische Chemie and Center of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, 30167 Hannover, Germany.
Kirschning
Andreas
A
D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011108:Polymers / Q000737:chemistry*; D015038:Zineb / Q000737:chemistry*
D011108:Polymers; D015038:Zineb