title: An audit of oral diseases at a Nairobi centre, 2000-2004.
abstract: OBJECTIVE
  To describe oral diseases diagnosed in an urban referral centre in Kenya in terms of age, gender and anatomical distribution and to compare this with reports in the literature.
  
  
  METHODS
  A retrospective histopathological audit.
  
  
  METHODS
  Oral Pathology Laboratory at the University of Nairobi Dental Hospital, a tertiary referral centre in Kenya.
  
  
  RESULTS
  548 (53.83%) patients were diagnosed with oral and maxillofacial tumours. Benign tumours (mean age +/- SD = 29.93 +/- 18.27 years) peaked in the third decade and tended to affect men at a younger age (p = 0.001). The most common benign tumour was the ameloblastoma (50.23%: n = 109), which predominantly affected the mandible, and also occurred in male patients at a younger age (p = 0.023). Peak incidences for malignant disease were observed in the sixth decade (mean age +/- SD = 46.94 +/- 18.99 years). Oral squamous cell carcinoma (OSCC) was the most common malignant tumour (59.55%; n = 187); occurring in the tongue, floor of the mouth, buccal mucosa and palate. 10.30% of OSCC occurred in patients under 40 years of age. 147 patients presented with cysts, which were mainly (68.10%) of odontogenic origin. Reactive lesions, infections, salivary gland diseases and autoimmune conditions constituted 26.60% of the case load.
  
  
  CONCLUSIONS
  The tendency of oral squamous cell carcinoma to occur in younger age groups may be an indication of carcinogenic factors that could be peculiar to this population. There is an urgent need for the expansion of reporting systems for oral diseases as an integral part of development of appropriate strategies in the improvement of general health in Kenya.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Oral Pathology and Medicine, Faculty of Dental Sciences, University of Nairobi, Kenya. eaodimba@yahoo.com
authors.forename: E A O
authors.initials: EA
authors.lastname: Dimba
authors.forename: J
authors.initials: J
authors.lastname: Gichana
authors.forename: A K
authors.initials: AK
authors.lastname: Limo
authors.forename: K A
authors.initials: KA
authors.lastname: Wakoli
authors.forename: M L
authors.initials: ML
authors.lastname: Chindia
authors.forename: D O
authors.initials: DO
authors.lastname: Awange
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000564:Ameloblastoma / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003560:Cysts / Q000453:epidemiology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000453:epidemiology; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000453:epidemiology*; D009062:Mouth Neoplasms / Q000453:epidemiology; D012189:Retrospective Studies; D017678:Sex Distribution