Variable presentation of post-traumatic hypopituitarism.
Post-traumatic hypopituitarism (PTHP) is defined as pituitary hormonal deficiency occurring after head injury. PTHP has recently been increasingly recognised as an important medical condition among survivors of head trauma. It can be fatal if undiagnosed, and may contribute to the morbidity and mortality associated with traumatic brain injury (TBI). Although about 75% of PTHP cases are diagnosed within a year of TBI,1 delayed development of PTHP can also occur.
Nirmalaraj
Kingsley
K
Department of Endocrinology, Greenlane Clinical Centre, Auckland, New Zealand.
Holdaway
Ian
I
D000063:Accidents, Traffic; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006259:Craniocerebral Trauma / Q000150:complications*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D013974:Thyroxine / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D013974:Thyroxine; D006854:Hydrocortisone