title: Repellent from traditional Chinese medicine, Periploca sepium Bunge.
abstract: By using a new bioassay-guided method, 2-hydroxy-4-methoxybenzaldehyde isolated from the root bark of Periploca sepium, a traditional Chinese medicine, showed repellent activity against the olive weevil (Dyscerus perforatus) at 62.5, 125, 250 and 500 microg/disc, respectively. In addition, it also exhibited antinematodal activity against Bursaphelenchus xylophilus at a minimum effective dose of 200 microg/ball. The three related compounds obtained were also evaluated for the above-mentioned bioactivities.
authors.affiliation: Graduate School of Natural Science and Technology, Department of Applied Bioscience and Biotechnology, Laboratory of Natural Products Chemistry, Okayama University, Japan.
authors.forename: Jianxiao
authors.initials: J
authors.lastname: Shi
authors.forename: Tomoko
authors.initials: T
authors.lastname: Yamashita
authors.forename: Ayumi
authors.initials: A
authors.lastname: Todo
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Nitoda
authors.forename: Minoru
authors.initials: M
authors.lastname: Izumi
authors.forename: Naomichi
authors.initials: N
authors.lastname: Baba
authors.forename: Shuhei
authors.initials: S
authors.lastname: Nakajima
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000295:instrumentation / Q000379:methods; D002681:China; D007302:Insect Repellents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008516:Medicine, Chinese Traditional; D009348:Nematoda / Q000187:drug effects; D031109:Periploca / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013329:Structure-Activity Relationship; D048889:Weevils / Q000187:drug effects
chemical_list: D007302:Insect Repellents; D010938:Plant Oils