title: A novel simple hemoglobin dilution technique to measure hemodialysis vascular access flow.
abstract: Measurement of the vascular access flow rate (Q(a)) is a widely accepted method for surveillance and predicting access failure. Among current practical methods, the ultrasound dilution technique is standard, but this requires a costly device available in few hemodialysis (HD) centers. Here, we devised a simple hemoglobin dilution technique to accurately measure Q(a) without the need for any special machines. Before HD, values of Q(a) were determined in each of 30 patients by hemoglobin dilution and then, in the same session, by ultrasound dilution. There was a significant correlation between the two techniques using automated hemoglobin and hematocrit or centrifuge-measured hematocrit levels to calculate HD fluid-derived Q(a) values. Our study shows that the HD dilution technique, using no special device, is economical, highly accurate, and easy to perform, and can be used as an alternative to standard ultrasound dilution for vascular access surveillance.
authors.affiliation: Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: K
authors.initials: K
authors.lastname: Tiranathanagul
authors.forename: P
authors.initials: P
authors.lastname: Katavetin
authors.forename: P
authors.initials: P
authors.lastname: Injan
authors.forename: A
authors.initials: A
authors.lastname: Leelahavanichkul
authors.forename: N
authors.initials: N
authors.lastname: Techawathanawanna
authors.forename: K
authors.initials: K
authors.lastname: Praditpornsilpa
authors.forename: N
authors.initials: N
authors.lastname: Srisawat
authors.forename: K
authors.initials: K
authors.lastname: Tungsanga
authors.forename: S
authors.initials: S
authors.lastname: Eiam-Ong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002408:Catheters, Indwelling; D005260:Female; D006454:Hemoglobins; D006801:Humans; D007201:Indicator Dilution Techniques; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D006454:Hemoglobins