title: Secondary amyloidosis associated with histiocytosis X.
abstract: We report a 34-year-old man diagnosed with Langerhans cell histiocytosis (LCH) or histiocytosis X in 1980. He had multiple focal osseous lesions, difficult control of the disease activity and was treated many times with chemo- and radiotherapy for symptomatic control. His kidney disease started 20 years after the diagnosis with progressive renal failure and increasing non-nephrotic proteinuria, coinciding with two flares of LCH. A percutaneous renal biopsy demonstrated amyloidosis. There is only one case described in the amyloidosis literature associated with LCH.
authors.forename: J
authors.initials: J
authors.lastname: Pérez-Martínez
authors.forename: M
authors.initials: M
authors.lastname: Marques
authors.forename: L
authors.initials: L
authors.lastname: Kilmurray
authors.forename: I
authors.initials: I
authors.lastname: Medina
authors.forename: S H
authors.initials: SH
authors.lastname: Nam-Cha
authors.forename: F
authors.initials: F
authors.lastname: Llamas
authors.forename: C
authors.initials: C
authors.lastname: Gómez
authors.forename: A
authors.initials: A
authors.lastname: Barrientos
authors.forename: J
authors.initials: J
authors.lastname: Blanco
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D001706:Biopsy; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D011507:Proteinuria / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D051437:Renal Insufficiency / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy