title: Seroprevalence of hepatitis A in thai army medical cadets and nursing students: a reflection of regional risk differences.
abstract: A cross-sectional study of 432 army college students comprising 278 medical cadets and 154 nursing students, ages ranging from 15 to 26 years, was conducted in 2001 to determine the seroprevalence of hepatitis A virus (HAV) antibody. Serum specimens were tested for HAV antibody by a commercial enzyme immunoassay method. Anti-HAV was detected in 14.0%, 17.5%, and 15.3% of medical cadets, nursing students, and the total cohort, respectively. There was no statistically significant difference in seroprevalence between medical cadets and nursing students. Increasing prevalence of HAV correlated with increasing age. Significantly higher seroprevalence was detected in students from provinces outside of Bangkok compared to those who were from Bangkok (18.7% vs. 9.8%). The highest HAV seroprevalence was observed in subjects from the northeastern region of Thailand, suggesting that this region may be associated with greater risk for infection and should be the focus of preventive health strategies.
authors.affiliation: Department of Pediatrics, RTA Medical Department, Phramongkutklao Hospital, Rajavithi Bangkok 10400, Thailand.
authors.forename: Rudiwilai
authors.initials: R
authors.lastname: Samakoses
authors.forename: Khin Saw Aye
authors.initials: KS
authors.lastname: Myint
authors.forename: Ram
authors.initials: R
authors.lastname: Rangsin
authors.forename: Wirote
authors.initials: W
authors.lastname: Areekul
authors.forename: Angkool
authors.initials: A
authors.lastname: Kerdpanich
authors.forename: Veerachai
authors.initials: V
authors.lastname: Watanaveeradej
authors.forename: Mammen P
authors.initials: MP
authors.lastname: Mammen
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005843:Geography; D006506:Hepatitis A / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D008297:Male; D008887:Military Medicine; D008889:Military Personnel; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013337:Students, Medical; D013338:Students, Nursing; D013785:Thailand / Q000453:epidemiology