[Antibacterial activity and property of the fermentation product of marine Streptomyces sp. GB-2].
Marine Streptomyces GB-2, isolated from marine samples collected in the intel tidal zone of Lianyungang, was found to produce antibacterial substance which exhibited significant inhibitory effects on 11 Gram-positive bacteria and 4 Gram-negative bacteria. The antibacterial substance was proved to be neutral and water-soluble according to paper chromatogram analysis, and its production was significantly associated with aritificial seawater. The stability analysis of the fermentation broth of Streptomyces GB-2 showed that it was very stable at pH1 and pH12 under 121 degrees C and changed very little under ultraviolet treatment. The substance produced by strain GB-2 exhibited potential use in the areas of bio-control, food and medical application.
Liu
Shu
S
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Lu
Ying-Jian
YJ
Lu
Zhao-Xin
ZX
Lü
Feng-Xia
FX
Bie
Xiao-Mei
XM
Fang
Yao-Wei
YW
Ding
Zhong-Yang
ZY
D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D012623:Seawater / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D013302:Streptomyces / Q000737:chemistry*
D000900:Anti-Bacterial Agents