[Acute renal insufficiency after flurbiprofen treatment in a patient treated with angiotensin converting enzyme inhibitor].
We report a case of acute renal insufficiency in a 77 year-old patient who took flurbiprofen as antiplatelet therapy. This is an important observation because it illustrates the potential risk of acute renal insufficiency, when using flurbiprofen before invasive medical examination or surgery in patients receiving long-term treatment with angiotensin converting enzyme inhibitors or angiotensin II inhibitors. This risk is probably underestimated in usual clinical practice.
Banal
F
F
Service de médecine interne, hôpital d'instruction des armées du Val-de-Grâce, Val-de-Grâce, 74, boulevard de Port-Royal, 75005 Paris, France. frederic.banal@neuf.fr
Lecoules
S
S
Carmoi
T
T
Thomas
L
L
Bonnefoy
S
S
Béchade
D
D
Desramé
J
J
Algayres
J P
JP
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003930:Diabetic Retinopathy; D005480:Flurbiprofen / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects; D017257:Ramipril / Q000009:adverse effects
D000806:Angiotensin-Converting Enzyme Inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000959:Antihypertensive Agents; D010975:Platelet Aggregation Inhibitors; D005480:Flurbiprofen; D017257:Ramipril