[Acute renal failure due to thrombotic microangiopathy associated with Castleman's disease].
We report a case of a 30-year-old man presenting with abdominal pain, fever, homodynamic instability, hepatosplenomegaly, acute renal failure, cervical lymph nodes, anaemia and thrombocytopenia. The patient was treated with empiric antibiotics, high dose corticosteroids, gammaglobulins, noradrenalin and diary intermittent haemodialysis, with an excellent response. The renal biopsy showed a thrombotic microangiopathy, the lymph node biopsy showed a Castleman s disease. Castleman s disease (also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia) is a clinicopathological entity of unknown aetiology. A number of renal alterations have been described in association with the Castleman s disease.
López Montes
A
A
Seccíon de Nefrología, Hospital General Universitario, Albacete, Spain. auroralmontes@hotmail.com
Andrés Mompeán
E
E
Martínez Villaescusa
M
M
Llamas Fuente
F
F
García-Mauriño Guelbenzu
M L
ML
D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D005871:Castleman Disease / Q000150:complications*; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000150:complications*