Novel variant of tickborne encephalitis virus, Russia.
We isolated a novel strain of tickborne encephalitis virus (TBEV), Glubinnoe/2004, from a patient with a fatal case in Russia. We sequenced the strain, whose landmark features included 57 amino acid substitutions and 5 modified cleavage sites. Phylogenetically, Glubinnoe/2004 is a novel variant that belongs to the Eastern type of TBEV.
Ternovoi
Vladimir A
VA
State Research Center of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, Russia.
Protopopova
Elena V
EV
Chausov
Eugene V
EV
Novikov
Dmitry V
DV
Leonova
Galina N
GN
Netesov
Sergey V
SV
Loktev
Valery B
VB
D000293:Adolescent; D000595:Amino Acid Sequence; D001483:Base Sequence; D004669:Encephalitis Viruses, Tick-Borne / Q000145:classification* / Q000302:isolation & purification; D004675:Encephalitis, Tick-Borne / Q000453:epidemiology / Q000821:virology*; D017809:Fatal Outcome; D005838:Genotype; D006801:Humans; D008297:Male; D010802:Phylogeny; D012426:Russia / Q000453:epidemiology