[Difficult treatment of amiodarone-induced thyrotoxicosis: a case report].
Amiodarone causes changes in thyroid function tests in about 15-20% of patients, inducing either hypothyroidism or thyrotoxicosis. The iodine load and the destructive thyroiditis caused by amiodarone produce thyrotoxicosis. We report a case of amiodarone-induced thyrotoxicosis diagnosed when investigating the reason for worsening of cardiac function. Prognosis and treatment of cardiac disorder were determined by thyrotoxicosis. The management needed a closed monitoring of thyroid function. Treatment was based on high doses of propylthiouracil and dexamethasone, but they couldn t control cardiac condition and surgery was warranted. When amiodarone-induced thyrotoxicosis is refractory to medical treatment, we believe surgery should be considered earlier.
Pedro
T
T
Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario, Departamento de Medicina, Universidad de Valencia, Valencia. teresapedrofont@hotmail.com
Martínez-Hervás
S
S
Lorente
R
R
Catalá
M
M
Ortega
J
J
Real
J T
JT
Carmena
R
R
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000628:therapy*
D000638:Amiodarone