title: [Measures to prevent or delay type 2 diabetes mellitus].
abstract: --The incidence of type 2 diabetes mellitus is increasing, as is the rate of related long-term complications. --Increased body weight and lack of exercise are the major non-genetic factors that are responsible for the increased incidence of type 2 diabetes mellitus. --People predisposed to developing type 2 diabetes mellitus can be identified easily by taking a patient history (e.g. genetic predisposition, gestational diabetes, medication), performing a physical examination (e.g. body-mass index, fat distribution) and laboratory tests (e.g. impaired fasting and post-load blood glucose levels). --Intensive lifestyle modifications reduce the risk of type 2 diabetes mellitus by 42-58%. --Drug therapy is less effective than lifestyle modifications in the prevention of type 2 diabetes mellitus. Moreover, the disease course after treatment is discontinued is unknown. --Successful intervention resulting in a sustained effect is expected to have a preventive effect on the long-term complications of type 2 diabetes mellitus.
authors.affiliation: Leids Universitair Medisch Centrum, afd. Algemene Interne Geneeskunde, Leiden. i.m.jazet@lumc.nl
authors.forename: I M
authors.initials: IM
authors.lastname: Jazet
authors.forename: A E
authors.initials: AE
authors.lastname: Meinders
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D015994:Incidence; D008019:Life Style; D009765:Obesity / Q000150:complications* / Q000378:metabolism; D012307:Risk Factors