title: [Clinical characteristics of Cronkhite-Canada syndrome in Chinese: meta-analysis of 35 cases].
abstract: OBJECTIVE
  To investigate the clinical characteristics of Chinese patients with Cronkhite-Canada syndrome (CCS).
  
  
  METHODS
  Relevant data of Chinese CCS patients from 1985 to 2006 were retrieved from Medline and Chinese biomedical database and a meta-analysis was conducted.
  
  
  RESULTS
  A total of 35 CCS cases had been reported by Chinese hospitals with the clinical characteristics of gastrointestinal polyposis with ectodermal trilogy, mainly manifested as diarrhea, bellyache, weight loss, anemia, and edema. Canceration was reported in 2 patients. Some patients had symptomatic response to combination therapy. There might be racial or regional differences in CCS susceptibility; however, such information was often neglected in the medical records at home and abroad. New techniques, such as (99)Tc(m)-HSA scan, double-balloon enteroscopy and wireless capsule endoscopy provided new information on CCS.
  
  
  CONCLUSIONS
  The clinical features of Chinese CCS patients are similar to those of the European or Japanese patients. Novel appliance, case report standardization and sharing database may promote the understanding of this rare syndrome.
authors.affiliation: Department of Gastroenterology of Tianjin Medical University General Hospital, Tianjin 300052, China.
authors.forename: Xiao-Cang
authors.initials: XC
authors.lastname: Cao
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Juan-Juan
authors.initials: JJ
authors.lastname: Ding
authors.forename: Jia
authors.initials: J
authors.lastname: Lian
authors.forename: Ning
authors.initials: N
authors.lastname: Lu
authors.forename: Bang-Mao
authors.initials: BM
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D006801:Humans; D044483:Intestinal Polyposis / Q000473:pathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged