[Results of myasthenia gravis treated with thymectomy].
OBJECTIVE
To evaluate the effectiveness of thymectomy for myasthenia gravis (MG) and the relative risk factors for postoperative myasthenic crisis.


METHODS
The clinic data of 78 cases with MG who underwent thymectomy from June 1985 to June 2005 were analyzed retrospectively. The relative risk factors of postoperative myasthenic crisis were analyzed and the differences between new and old region of perioperative management were compared.


RESULTS
The symptom of MG was complete remission in 21 cases, significantly improved in 38 cases, improved in 11 cases and unchanged in 8 cases, respectively. The symptom duration before operation, preoperative serum level of anti-acetylcholine receptor antibody, Osserman stage and pathological type of thymoma were independent relative risk factors for postoperative myasthenic crisis. The new region of perioperative management was significant better than the old one.


CONCLUSIONS
Surgical treatment shows significant clinical benefits for patients with MG.
Zhang
Hai-tao
HT
Department of Thoracic Surgery, China-Japan Friendship Hospital, Beijing 100029, China.
Liu
De-ruo
DR
Guo
Yong-qing
YQ
Ge
Bing-sheng
BS
Tian
Yan-chu
YC
Shi
Bin
B
Liang
Chao-yang
CY
D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology / Q000517:prevention & control; D009157:Myasthenia Gravis / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D012189:Retrospective Studies; D013934:Thymectomy / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome