title: Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis.
abstract: Melioidosis is an infectious disease endemic to northern Australia and Southeast Asia. In response to clinical confusion regarding the appropriate dose of amoxicillin-clavulanate, we have developed guidelines for the appropriate dosing of this second-line agent. For eradication therapy for melioidosis, we recommend 20/5 mg/kg orally, three times daily.
authors.affiliation: Department of Medicine, University of Melbourne, Melbourne, Australia. allen.cheng@menzies.edu.au
authors.forename: Allen C
authors.initials: AC
authors.lastname: Cheng
authors.forename: Wirongrong
authors.initials: W
authors.lastname: Chierakul
authors.forename: Wipada
authors.initials: W
authors.lastname: Chaowagul
authors.forename: Ploenchan
authors.initials: P
authors.lastname: Chetchotisakd
authors.forename: Direk
authors.initials: D
authors.lastname: Limmathurotsakul
authors.forename: David A B
authors.initials: DA
authors.lastname: Dance
authors.forename: Sharon J
authors.initials: SJ
authors.lastname: Peacock
authors.forename: Bart J
authors.initials: BJ
authors.lastname: Currie
mesh_terms: D000284:Administration, Oral; D000328:Adult; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002648:Child; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008554:Melioidosis / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D019980:Amoxicillin-Potassium Clavulanate Combination