title: Prevalence and risk factors for Chlamydia trachomatis infection in young women in north-west of Italy.
abstract: OBJECTIVE
  The aim of the study was to estimate the prevalence of Chlamydia trachomatis infection, risk factors and best predictors of infection in young sexually active women in north-west of Italy.
  
  
  METHODS
  One thousand one hundred and eighty 18-24 years old women of family planning clinics and three STI Clinics over Turin city area underwent vaginal swabs to detect infection and completed a questionnaire. Logistic regression and multivariate analysis identified risk factors and a receiver operating characteristic (ROC) curve was used to assess the model accuracy.
  
  
  RESULTS
  Overall prevalence of infection was 10.4% 2.71 times higher (P<0.001) among women afferent to STI clinics than family planning clinics. Higher among women of Eastern European, Asian and South American ethnic origin (P=0.012) compared to Western European or African ethnic origin. Age at first intercourse (P=0.006), absence of a stable partner (P<0.001) partner with urogenital complaints (P<0.001), number of lifetime partners (P<0.001) number of partners in the last 6 months (P<0.001) history of occasional intercourse (P<0.001) and of IST (P<0.007) resulted associated with chlamydial infection. Multivariate analysis showed setting, partner with urogenital complaints and number of lifetime partners as best predictors of infection. ROC curve on variables from multivariate analysis showed an AUC of 0.732.
  
  
  CONCLUSIONS
  The study showed high rates of Chlamydial infection among sexually active women between 18-24 years in north-west area of Italy. Predictors of infection are related to sexual activity and to population sub-groups. Selective screening protocols should be supported by wider and more representative studies in order to increase knowledge and involve public opinion.
authors.affiliation: Department of Bacteriology, OIRM Sant'Anna Hospital, Turin, Italy.
authors.forename: M A
authors.initials: MA
authors.lastname: Latino
authors.forename: A
authors.initials: A
authors.lastname: Caneparo
authors.forename: C
authors.initials: C
authors.lastname: Rosso
authors.forename: D
authors.initials: D
authors.lastname: De Maria
authors.forename: G
authors.initials: G
authors.lastname: De Intinis
authors.forename: P
authors.initials: P
authors.lastname: Intorcia
authors.forename: M
authors.initials: M
authors.lastname: Petrinco
mesh_terms: D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000453:epidemiology*; D002692:Chlamydia trachomatis; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D016015:Logistic Models; D015999:Multivariate Analysis; D015995:Prevalence; D012372:ROC Curve; D012307:Risk Factors; D012725:Sexual Behavior