Hyper-reactive malarial splenomegaly in a patient with human immunodeficiency virus.
Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.
De Iaco
G
G
Infectious and Tropical Medicine Institute, University of Brescia, Italy.
Saleri
N
N
Perandin
F
F
Gulletta
M
M
Ravizzola
G
G
Manca
N
N
Signorini
L
L
Matteelli
A
A
Prestini
K
K
Castelli
F
F
D000818:Animals; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000913:Antibodies, Protozoan / Q000097:blood; D000962:Antimalarials / Q000627:therapeutic use; D002163:Cameroon / Q000208:ethnology; D003937:Diagnosis, Differential; D005260:Female; D006678:HIV / Q000302:isolation & purification; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007558:Italy; D008288:Malaria / Q000150:complications* / Q000175:diagnosis*; D015767:Mefloquine / Q000627:therapeutic use; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D013163:Splenomegaly / Q000175:diagnosis / Q000209:etiology*
D019380:Anti-HIV Agents; D000913:Antibodies, Protozoan; D000962:Antimalarials; D012337:RNA, Ribosomal, 18S; D015767:Mefloquine