Therapy-resistant skin ulcers on hypoplastic leg associated with neurofibromatosis type 1.
We describe a case of therapy-resistant skin ulcers in sporadic neurofibromatosis type 1. A 40-year-old woman had suffered from neurofibromata on her trunk and extremities since 30 years prior. She suffered from hypoplasia of her right leg from a young age and had a 1-year history of therapy-resistant skin ulcers on the leg and inguinal region. Magnetic resonance angiography disclosed a narrowed femoral artery at the level of the upper thigh with poor root in the inner side corresponding to the ulcerated lesions. The vascular changes were thought to be the cause of the skin ulcers.
Fujimura
Taku
T
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Okuyama
Ryuhei
R
Aiba
Setsuya
S
D000328:Adult; D004351:Drug Resistance; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology* / Q000473:pathology / Q000628:therapy*; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology