Characteristics and outcomes of patients with seizures according to the time of onset in relation to stroke.
OBJECTIVE
Although most late-onset seizures (LS) appear within 2 years after stroke, some of them occur later and their characteristics are unknown. The aim of this study was to compare the characteristics of patients with very-late-onset seizures (VLS) to those with early-onset seizures (ES) and those with LS.


METHODS
The study group consisted of 204 patients with stroke-related seizures (29 ES, 128 LS and 47 VLS).


RESULTS
Intracranial haemorrhage was a more frequent cause of ES than of LS and no cause at all of VLS. On the other hand, 25% of the VLS were related to lacunar strokes. Status epilepticus occurred in 20.7% of the ES, in 11.7% of the LS and in 2.1% of the VLS patients. Seizure recurrences were 13.8% in the ES, 54.7% in the LS and 34.0% in the VLS group. Neurological impairment, at stroke onset, and the degree of disability were more severe in patients with ES compared to those with LS and were very mild in the VLS group. The EEG findings as a whole did not show significant differences between the three groups, although a normal EEG was more frequent in the VLS group.


CONCLUSIONS
VLS occur in patients with minor ischaemic strokes with good recovery and benign disease course.
De Reuck
J
J
Department of Neurology, University Hospital, Ghent, Belgium. dereuck.j@gmail.com
Sieben
A
A
Van Maele
G
G
D000368:Aged; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D020127:Recovery of Function; D012640:Seizures / Q000453:epidemiology* / Q000209:etiology*; D020521:Stroke / Q000150:complications*; D013995:Time