title: [Secretome: definitions and biomedical interest].
abstract: BACKGROUND
  The secretome, or secretomics refers to the global study of proteins that are secreted by a cell, a tissue or an organism.
  
  
  METHODS
  The secretome is an important class of proteins that control many biological and physiological processes. Many secretion pathways are implicated in the release of these proteins.
  
  
  CONCLUSIONS
  The secretome is a potential source suitable for the discovery of new therapeutic targets or biomarker candidates.
authors.affiliation: Centre de recherche Inserm/UJF U823, équipe 5 - cibles diagnostiques ou thérapeutiques et vectorisation des drogues dans le cancer du poumon, institut Albert-Bonniot, 38042 Grenoble, France.
authors.forename: J
authors.initials: J
authors.lastname: Chenau
authors.forename: S
authors.initials: S
authors.lastname: Michelland
authors.forename: M
authors.initials: M
authors.lastname: Seve
mesh_terms: D006801:Humans; D008967:Molecular Biology / Q000379:methods; D011506:Proteins / Q000378:metabolism*; D020543:Proteome; D040901:Proteomics
chemical_list: D011506:Proteins; D020543:Proteome