title: Periapical tissue healing after post space preparation with or without use of a protection plug and root canal exposure to the oral environment. Study in dogs.
abstract: The purpose of this study was to evaluate the influence of coronal leakage on the healing of dogs' periapical tissues after root canal filling, post space preparation and protection or not with a temporary sealer plug. Forty root canals of dogs' teeth were instrumented and filled by the lateral condensation technique with gutta-percha points and Endomethasone or CRCS sealers. After post space preparation, the remaining filling material was protected or not with a plug of temporary Coltosol sealer and exposed to the oral environment for 90 days. Thereafter, the animals were sacrificed and the specimens were removed and prepared for histomorphological and histobacteriological analysis. The findings revealed 35% of microbial leakage in the groups without plugs and 15% of leakage in the groups with plugs. Statistical analysis showed that the use of a Coltosol plug improved significantly the histomorphological results regardless of the type of root canal sealer (p=0.05) and that CRCS and Endomethasone sealers showed similar results (p>0.05).
authors.affiliation: Department of Restorative Dentistry, School of Dentistry of Araçatuba, São Paulo State University, Araçatuba, SP, Brazil. rholland@foa.unesp.br
authors.forename: Roberto
authors.initials: R
authors.lastname: Holland
authors.forename: Luciana Noronha
authors.initials: LN
authors.lastname: Manne
authors.forename: Valdir
authors.initials: V
authors.lastname: de Souza
authors.forename: Sueli Satomi
authors.initials: SS
authors.lastname: Murata
authors.forename: Eloi
authors.initials: E
authors.lastname: Dezan Júnior
mesh_terms: D000818:Animals; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002133:Calcium Sulfate / Q000627:therapeutic use; D003739:Dental Cementum / Q000473:pathology; D003763:Dental Leakage / Q000382:microbiology; D003782:Dental Pulp / Q000473:pathology; D003786:Dental Pulp Cavity / Q000473:pathology*; D003804:Dentin / Q000473:pathology; D003907:Dexamethasone / Q000627:therapeutic use; D004285:Dogs; D004338:Drug Combinations; D005557:Formaldehyde / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006171:Gutta-Percha / Q000627:therapeutic use; D006854:Hydrocortisone / Q000627:therapeutic use; D010486:Periapical Tissue / Q000473:pathology*; D010513:Periodontal Ligament / Q000473:pathology; D011176:Post and Core Technique; D020011:Protective Agents / Q000627:therapeutic use*; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D012389:Root Canal Obturation / Q000379:methods*; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods; D013943:Thymol / Q000031:analogs & derivatives / Q000627:therapeutic use; D019227:Tooth Apex / Q000473:pathology; D014945:Wound Healing / Q000502:physiology; D015034:Zinc Oxide / Q000627:therapeutic use; D019287:Zinc Sulfate / Q000627:therapeutic use
chemical_list: C504942:Coltosol F; D004338:Drug Combinations; D020011:Protective Agents; D012387:Root Canal Filling Materials; C011244:corticosteroid methanetriol mixture; C075563:Calcibiotic Root Canal Sealer; D005557:Formaldehyde; D013943:Thymol; D019287:Zinc Sulfate; D003907:Dexamethasone; D006171:Gutta-Percha; D002126:Calcium Hydroxide; D015034:Zinc Oxide; D002133:Calcium Sulfate; D006854:Hydrocortisone