Molecular control of memory in nematode Caenorhabditis elegans.
Model invertebrate organism Caenorhabditis elegans has become an ideal model to unravel the complex processes of memory. C. elegans has three simple forms of memory: memory for thermosensation, memory for chemosensation, and memory for mechanosensation. In the form of memory for mechanosensation, short-term memory, intermediate-term memory, and long-term memory have been extensively studied. The short-term memory and intermediate-term memory may occur in the presynaptic sensory neurons, whereas the long-term memory may occur in the postsynaptic interneurons. This review will discuss the recent progress on genetic and molecular regulation of memory in C. elegans.
Ye
Hua-Yue
HY
School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Ye
Bo-Ping
BP
Wang
Da-Yong
DY
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D008568:Memory / Q000502:physiology*; D023421:Models, Animal