title: [Retrospective analysis of three cases of pulmonary mucormycosis].
abstract: OBJECTIVE
  To describe the clinical characteristics of pulmonary mucormycosis and to evaluate the approaches to its diagnosis and treatment.
  
  
  METHODS
  Three cases of pulmonary mucormycosis were successfully diagnosed by histopathologic examination of infected tissues obtained by fiberoptic bronchoscopy in this hospital. The clinical features of the cases were analyzed and the literature reviewed.
  
  
  RESULTS
  Three patients were all farmers and two of them had had diabetic ketoacidosis. The first patient died from massive hemoptysis one day after the diagnosis was confirmed. The second patient was cured by large doses of intravenous amphotericin B (total dosage 2 g). The third patient presented with right middle bronchial stenosis after right upper lobectomy because of squamous carcinoma, and was cured by amphotericin B (1.5 g) combined with interventional therapy under fiberoptic bronchoscopy. The two patients were followed for 0.5 - 1 year without relapse.
  
  
  CONCLUSIONS
  The mortality of pulmonary mucormycosis is high. Fiberoptic bronchoscopy is a useful diagnostic method for histopathologic examination. Successful treatment of pulmonary mucormycosis includes early diagnosis, control of underlying diseases and surgical intervention of isolated lesions combined with large dosage of amphotericin B.
authors.affiliation: Department of Respiratory Medicine, Peking University First Hospital, Beijing 100034, China.
authors.forename: Xiang-dong
authors.initials: XD
authors.lastname: Mu
authors.forename: Guang-fa
authors.initials: GF
authors.lastname: Wang
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Diao
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Hai-chao
authors.initials: HC
authors.lastname: Li
authors.forename: Gui-lian
authors.initials: GL
authors.lastname: Li
authors.forename: Cheng-li
authors.initials: CL
authors.lastname: Que
authors.forename: Bing
authors.initials: B
authors.lastname: He
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis / Q000628:therapy