title: Rapid control of malaria by means of indoor residual spraying of alphacypermethrin in the Democratic Republic of São Tomé and Príncipe.
abstract: A nationwide yearly cycle of indoor residual spraying (IRS) with a pyrethroid, alphacypermethrin, at a dosage of 50 mg/m(2) was instituted in 2004 in the Democratic Republic of São Tomé and Príncipe. Rates of IRS acceptance were high, varying from 82% to 95% for dwellings and outhouses. Epidemiologic surveys of the children < 9 years of age before and after the first IRS cycle revealed a rapid reduction in malaria. Overall prevalence of malaria parasitemia for all districts was lowered from 20.1% to 2.8% at 12 months after the first IRS and reached 0.7% at 8 months after the second IRS. Longer insecticidal persistence was found on wood than on cement with alphacypermethrin.
authors.affiliation: The Anti-Malaria Team of Taiwan, Medical Mission to São Tomé and Príncipe, São Tomé and Príncipe.
authors.forename: Lien Fen
authors.initials: LF
authors.lastname: Tseng
authors.forename: Wen Chun
authors.initials: WC
authors.lastname: Chang
authors.forename: Maria Conceição
authors.initials: MC
authors.lastname: Ferreira
authors.forename: Cheng Hua
authors.initials: CH
authors.lastname: Wu
authors.forename: Herodes Sacramento
authors.initials: HS
authors.lastname: Rampão
authors.forename: Jih Ching
authors.initials: JC
authors.lastname: Lien
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology; D001266:Atlantic Islands / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006798:Housing; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D007306:Insecticides; D008288:Malaria / Q000453:epidemiology / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods*; D018512:Parasitemia / Q000453:epidemiology / Q000517:prevention & control; D010961:Plasmodium / Q000302:isolation & purification; D011722:Pyrethrins; D013997:Time Factors; D014934:Wood
chemical_list: D007306:Insecticides; D011722:Pyrethrins; C017160:cypermethrin