title: Waveform diversity based ultrasound system for hyperthermia treatment of breast cancer.
abstract: In this letter, we present a new waveform-diversity-based ultrasound hyperthermia technique for the treatment of breast cancer. Waveform diversity offers a new paradigm for beampattern design. By choosing a proper covariance matrix of the transmitted waveforms under the uniform elemental power constraint, the ultrasound system can provide a focal spot matched to the entire tumor region, and meanwhile, minimize the impact to the surrounding healthy breast tissues. As shown in our 2-D numerical simulations, this method has better acoustic power deposition than the existing methods, and can provide the necessary temperature gradients required for the effective hyperthermia treatment of breast cancer.
authors.affiliation: Department of Electrical and Computer Engineering, University of Florida, P.O. Box 116130, Gainesville, FL 32611 USA. guobin@dsp.ufl.edu
authors.forename: Bin
authors.initials: B
authors.lastname: Guo
authors.forename: Jian
authors.initials: J
authors.lastname: Li
mesh_terms: D001943:Breast Neoplasms / Q000628:therapy*; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation* / Q000379:methods; D008962:Models, Theoretical; D014465:Ultrasonics