Selective benzylic C-C coupling catalyzed by a bioinspired dicopper complex.
A highly preorganized bioinspired dicopper complex with imidazole ligation catalyzes the selective benzylic para-C-H activation of 2,4,6-trimethylphenol under aerobic conditions, yielding either the stilbenequinone or 4-methoxymethyl-2,6-dimethylphenol depending on the solvent used.
Prokofieva
Angelina
A
Institut für Anorganische Chemie, Georg-August-Universität, Tammannstrasse 4, D-37077, Göttingen, Germany.
Prikhod'ko
Alexander I
AI
Dechert
Sebastian
S
Meyer
Franc
F
D040761:Biomimetic Materials / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003408:Cresols / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry; D011809:Quinones / Q000138:chemical synthesis / Q000737:chemistry; D012997:Solvents / Q000737:chemistry
C528655:4-methoxymethyl-2,6-dimethylphenol; D003408:Cresols; D007093:Imidazoles; D008024:Ligands; D009942:Organometallic Compounds; D010636:Phenols; D011809:Quinones; D012997:Solvents; D003300:Copper; C505148:2,4,6-trimethylphenol