title: Persistent Bordetella bronchiseptica pneumonia in an immunocompetent infant and genetic comparison of clinical isolates with kennel cough vaccine strains.
abstract: An infant who experienced recurrent episodes of respiratory failure received a diagnosis of pertussis on the basis of immunofluorescence testing, but culture revealed macrolide-resistant Bordetella bronchiseptica. Genetic analysis demonstrated that the child was not infected with a kennel cough vaccine strain, although the family's dog had recently been vaccinated. The infection cleared with imipenem therapy.
authors.affiliation: Department of Pediatrics, Division of Infectious Diseases, Tulane University Health Sciences Center, New Orleans, Louisiana, USA. Barbara.Rath@gmail.com
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Rath
authors.forename: Karen B
authors.initials: KB
authors.lastname: Register
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Wall
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Sokol
authors.forename: Russell B
authors.initials: RB
authors.lastname: Van Dyke
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D001428:Bacterial Vaccines / Q000145:classification / Q000235:genetics; D001431:Bacteriological Techniques; D001885:Bordetella Infections / Q000382:microbiology; D016950:Bordetella bronchiseptica / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D003371:Cough / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D003470:Culture Media; D004283:Dog Diseases / Q000382:microbiology / Q000517:prevention & control*; D004285:Dogs; D006801:Humans; D007121:Immunocompetence; D007223:Infant; D018410:Pneumonia, Bacterial / Q000382:microbiology*
chemical_list: D001428:Bacterial Vaccines; D003470:Culture Media