An update on acute kidney injury after cardiac surgery.
Renal dysfunction following cardiac surgery is well recognised and mainly is of ischaemic origin. The spectrum varies from subclinical injuryto established renal failure requiring renal replacement therapy. Depending on definitions, acute kidney injury (AKI) may occur in up to 30% of post cardiac surgery patients. A new grading system for renal dysfunction, based on three levels of plasma creatinine and urine output, as well as the use of biomarkers may help the early identification of patients at risk and thereby hopefully improve outcome. Despite therapeutic advances, the morbidity and mortality associated with AKI have not changed markedly in the last decade.
Vaschetto
R
R
Department of Intensive Care Medicine, Vrije Universiteit Medical Centre, Amsterdam, The Netherlands.
Groeneveld
A B J
AB
D058186:Acute Kidney Injury / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control / Q000628:therapy; D000367:Age Factors; D000368:Aged; D001002:Anuria / Q000175:diagnosis; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D047549:Coronary Artery Bypass, Off-Pump; D003404:Creatinine / Q000097:blood; D004232:Diuretics / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D017582:Renal Replacement Therapy; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012737:Sex Factors; D013997:Time Factors
D004232:Diuretics; D003404:Creatinine