The effects of boron administration on plasma leptin and lactate levels in ovariectomized rats which had acute swimming exercise.
OBJECTIVE
The aim of this study was to investigate the effects of intraperitoneal (IP) boron administration on leptin and lactate levels in swimming exercise in ovariectomized rats.


METHODS
Eighty adult female rats were equally allocated into 8 groups. Group 1; Control, Group 2; exercise control, Group 3; ovariectomized control, Group 4; Boron control (2 mg/kg/day), Group 5; ovariectomized plus exercise, Group 6; exercise plus IP boron, Group 7; ovariectomized and exercise group plus IP boron, Group 8; ovariectomized plus boron.


RESULTS
Leptin levels in Group 1 were higher than those in Groups 2, 3 and 4 and lower than those in groups 5, 6, 7 and 8 (p<0.01). Leptin levels were higher in Group 3 than in Groups 2 and 4 and significantly lower than in all other groups (p<0.01). Lactate levels in Groups 2 and 4 were higher than those in all other groups (p<0.01). Lactate levels were significantly lower in Groups 1, 3, 5 and 8 than in all other groups (p<0.01). Lactate levels in Groups 6 and 7 were significantly lower than those in Groups 2 and 4 (p<0.01) and higher than those in groups 1, 3 and 5 (p<0.01).


CONCLUSIONS
The present findings demonstrate that ovariectomy and acute swimming exercise in rats led to a significant decrease in leptin levels and a significant increase in lactate levels and that boron administration prevented the increased in circulating lactate concentration induced by swimming exercise.
Yazici
Zubeyde
Z
Department of Physical Education and Sports Sciences, Selcuk University, Konya-Turkey, Turkey.
Kaya
Yalcin
Y
Baltaci
Abdulkerim Kasim
AK
Mogulkoc
Rasim
R
Oztekin
Esma
E
D000818:Animals; D001895:Boron / Q000494:pharmacology*; D005260:Female; D007773:Lactates / Q000097:blood*; D020738:Leptin / Q000097:blood*; D010052:Ovariectomy; D010805:Physical Conditioning, Animal / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013550:Swimming / Q000502:physiology*; D014131:Trace Elements / Q000494:pharmacology*
D007773:Lactates; D020738:Leptin; D014131:Trace Elements; D001895:Boron