Opposite effects of angiotensin II and angiotensin (1-7) on impulse propagation, excitability and cardiac arrhythmias. Is the overexpression of ACE2 arrhythmogenic?
De Mello
Walmor C
WC
Department of Pharmacology, School of Medicine Medical Sciences Campus, UPR, San Juan, PR 00936-5067, USA. wmello@rcm.upr.edu
D000200:Action Potentials / Q000187:drug effects*; D000803:Angiotensin I / Q000494:pharmacology*; D000804:Angiotensin II / Q000494:pharmacology*; D000085962:Angiotensin-Converting Enzyme 2; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000378:metabolism*; D006801:Humans; D010446:Peptide Fragments / Q000494:pharmacology*; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
D010446:Peptide Fragments; D000804:Angiotensin II; D000803:Angiotensin I; D007703:Peptidyl-Dipeptidase A; C000705307:ACE2 protein, human; D000085962:Angiotensin-Converting Enzyme 2; C118790:angiotensin I (1-7)