title: Balloon cells and dysmorphic neurons in the hippocampus associated with epileptic amnesic syndrome: a case report.
abstract: Recently, we encountered a 39-year-old woman with typical epileptic amnesic syndrome. The patient underwent right anterior temporal lobectomy, which removed the right hippocampus. The patient's resected hippocampus showed typical histological features of Ammon's horn sclerosis (AHS) with dysmorphic neurons. In addition, the prominent balloon cells, admixed with dysmorphic neurons, were noted in the hippocampus. To our knowledge, this is the first reported case showing AHS with balloon cells. The presence of balloon cells reinforces the hypothesis that AHS itself might be a maldevelopment disorder.
authors.affiliation: Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea.
authors.forename: Se Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Yang-Je
authors.initials: YJ
authors.lastname: Cho
authors.forename: Hyung
authors.initials: H
authors.lastname: Seok Kim
authors.forename: Kyoung
authors.initials: K
authors.lastname: Heo
authors.forename: Min-Cheol
authors.initials: MC
authors.lastname: Lee
authors.forename: Byung-In
authors.initials: BI
authors.lastname: Lee
authors.forename: Tai
authors.initials: T
authors.lastname: Seung Kim
authors.forename: Jin
authors.initials: J
authors.lastname: Woo Chang
mesh_terms: D000328:Adult; D020324:Amnesia, Anterograde / Q000473:pathology; D038481:Anterior Temporal Lobectomy; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000473:pathology* / Q000601:surgery; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D005682:Gadolinium; D006624:Hippocampus / Q000002:abnormalities / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D054220:Malformations of Cortical Development / Q000473:pathology* / Q000601:surgery; D009474:Neurons / Q000473:pathology*; D012598:Sclerosis / Q000473:pathology; D014743:Videotape Recording
chemical_list: D005682:Gadolinium