Multiple aggressive squamous skin cancers in association with nonbullous congenital ichthyosiform erythroderma.
Nonbullous congenital ichthyosiform erythroderma (NBCIE) is one of the autosomal recessive inherited non-syndromic ichthyoses and is currently diagnosed on clinical grounds alone. Skin cancer is not a recognized complication of NBCIE. We report here two NBCIE patients who have developed multiple aggressive nonmelanoma skin cancers, predominantly cutaneous squamous cell carcinoma. NBCIE may be a risk factor for skin cancer development.
Brown
V L
VL
Department of Dermatology, Churchill Hospital, Old Road, Headington, Oxford OX3 7LJ, UK. vbrown@doctors.org.uk
Farrant
P B J
PB
Turner
R J
RJ
Price
M L
ML
Burge
S M
SM
D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology*; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*