title: Beta-arrestins: multifunctional cellular mediators.
abstract: Initially thought to play a role only in G-protein-coupled receptor desensitization, beta-arrestins are ascribed with new roles such as scaffolding and signaling proteins by their own right. This review explores the many functions of beta-arrestins, with an emphasis on their recently identified role as regulators of receptor signaling.
authors.affiliation: Department of Biology, University of Haifa, Israel.
authors.forename: Liza
authors.initials: L
authors.lastname: Barki-Harrington
authors.forename: Howard A
authors.initials: HA
authors.lastname: Rockman
mesh_terms: D000818:Animals; D019390:Arrestins / Q000378:metabolism*; D004705:Endocytosis; D054768:G-Protein-Coupled Receptor Kinases / Q000378:metabolism; D006801:Humans; D008024:Ligands; D009206:Myocardium / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D021381:Protein Transport; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*; D015398:Signal Transduction; D000071557:beta-Arrestins
chemical_list: D019390:Arrestins; D008024:Ligands; D043562:Receptors, G-Protein-Coupled; D000071557:beta-Arrestins; D054768:G-Protein-Coupled Receptor Kinases