title: Insecticidal activity of major lichen compounds, (-)- and (+)-usnic acid, against the larvae of house mosquito, Culex pipiens L.
abstract: In this research, (-)-usnic acid and (+)-usnic acid, commonly encountered lichen secondary metabolites, were evaluated for their insecticidal effects against the larvae of Culex pipiens L. (Diptera: Culicidae) under laboratory conditions. Both compounds showed strong larvicidal activity and caused 100% mortality on third-fourth larval stages of the species at 24 h at the doses of 5 and 10 ppm. Bioassays with (-)- and (+)-usnic acids against larvae of C. pipiens revealed that the LC50 values were 0.8 and 0.9 ppm, respectively. The results suggest that lichen compounds could be useful in the search of new insecticides.
authors.affiliation: Department of Biology, Faculty of Arts and Science, Akdeniz University, 07070 Antalya, Turkey. hcetin@akdeniz.edu.tr
authors.forename: Huseyin
authors.initials: H
authors.lastname: Cetin
authors.forename: Ozge
authors.initials: O
authors.lastname: Tufan-Cetin
authors.forename: Ayse Ozdemir
authors.initials: AO
authors.lastname: Turk
authors.forename: Turgay
authors.initials: T
authors.lastname: Tay
authors.forename: Mehmet
authors.initials: M
authors.lastname: Candan
authors.forename: Atila
authors.initials: A
authors.lastname: Yanikoglu
authors.forename: Huseyin
authors.initials: H
authors.lastname: Sumbul
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000494:pharmacology*; D003465:Culex / Q000187:drug effects*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D008011:Lichens / Q000737:chemistry*; D015394:Molecular Structure; D016019:Survival Analysis
chemical_list: D001572:Benzofurans; D007306:Insecticides; C073339:usnic acid