title: Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report.
abstract: BACKGROUND
  Dementia is one of the most important neurological disorders in the elderly. Dementia of tumoral origin is rare and parkinsonism of neoplastic origin is unusual. We herein report a case of gliomatosis cerebri, a very rare brain tumor seldom affecting the elderly, which presented as rapidly progressive dementia and parkinsonism.
  
  
  METHODS
  An 82-year-old woman very rapidly developed progressive dementia and akineto-rigid parkinsonism. Brain CT scan was normal. Cerebral magnetic resonance imaging (MRI) with gadolinium injection highlighted a diffuse tumor-related infiltration involving both lobes, the putamen, the pallidum, the substantia nigra, and the brainstem, corresponding to the specific description and definition of gliomatosis cerebri.
  
  
  CONCLUSIONS
  This atypical presentation of a gliomatosis cerebri, and the infiltration of the substantia nigra by the tumor, merits attention.
authors.affiliation: Department of Geriatrics, University René Descartes, Broca Hospital, AP-HP, France. emmanuelle.duron@brc.aphp.fr
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Duron
authors.forename: Anne
authors.initials: A
authors.lastname: Lazareth
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Gaubert
authors.forename: Carole
authors.initials: C
authors.lastname: Raso
authors.forename: Olivier
authors.initials: O
authors.lastname: Hanon
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Rigaud