Oral malignancies associated with HIV.
Advances in the management of HIV infection have resulted in significant changes in survival and in the prevalence and incidence of oral diseases found in persons infected with HIV (as discussed in other articles in this series). HIV is associated with an increased risk of malignant disease that is related to immunosuppression and the activity of the HIV transactivator of transcription protein, coviral infection and exposure to carcinogens. The presence of oral malignancies varies with the route of the transmission of HIV and varies geographically, based on behaviour, viral cofactors, HIV therapy and genetic variation. Oral health care providers can identify these lesions early.
Epstein
Joel B
JB
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois at Chicago, Illinois 60091, USA. jepstein@uic.edu
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000209:etiology; D017742:Dental Care for Chronically Ill; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis / Q000209:etiology; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000209:etiology*; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000209:etiology; D054321:rev Gene Products, Human Immunodeficiency Virus / Q000502:physiology
D054321:rev Gene Products, Human Immunodeficiency Virus