Commentary to the article "Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro".
This note summarises recent studies on skin penetration of terpinen-4-ol, which is the main component of tea tree oil [S.E. Cross, M. Russell, I. Southwell, M.S. Roberts, Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro, Eur. J. Pharm. Biopharm. doi: 10.1016/j.ejpb.2007.10.002 (in press)]. The influence of different experimental models on obtained skin penetration results is discussed.
Cal
Krzysztof
K
Department of Pharmaceutical Technology, Medical University of Gdansk, Gdansk, Poland. kcal@wp.pl
D006801:Humans; D012867:Skin / Q000378:metabolism*; D020947:Tea Tree Oil / Q000493:pharmacokinetics*; D013729:Terpenes / Q000008:administration & dosage / Q000493:pharmacokinetics*
D013729:Terpenes; C034019:terpinenol-4; D020947:Tea Tree Oil