title: Time-dependent contrast functions for quantitative imaging in time-resolved transillumination experiments.
abstract: We have developed a methodology that can be used in reconstruction algorithms to quantify the optical coefficients and the geometrical cross section of a weakly abnormal optical target embedded in an otherwise homogeneous medium. This novel procedure uses differenttime-dependent point-spread functions to analyze the diffusive and absorptive contrasts obtained from time-of-flight measurements. Data obtained from time-resolved transillumination of a tissuelike phantom are used to test the accuracy of this new deconvolution methodology.
authors.forename: A H
authors.initials: AH
authors.lastname: Gandjbakhche
authors.forename: V
authors.initials: V
authors.lastname: Chernomordik
authors.forename: J C
authors.initials: JC
authors.lastname: Hebden
authors.forename: R
authors.initials: R
authors.lastname: Nossal