Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes.
Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.
Engström
Pär G
PG
Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate, N-5008 Bergen, Norway. par.engstrom@bccs.uib.no
Fredman
David
D
Lenhard
Boris
B
D000818:Animals; D030541:Databases, Genetic; D018507:Gene Expression Regulation, Developmental; D050437:Genes, Developmental; D005809:Genes, Regulator; D016678:Genome; D006801:Humans; D020407:Internet; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D020506:Untranslated Regions / Q000235:genetics*
D020506:Untranslated Regions