title: Inherent homogenous media dispersion compensation in frequency domain optical coherence tomography by accurate k-sampling.
abstract: Depth dependent broadening of the axial point spread function due to dispersion in the imaged media, and algorithms for postprocess correction, have been previously described for both time domain and frequency domain optical coherence tomography. We show that homogeneous media dispersion artifacts disappear when frequency domain samples are acquired with uniform spacing in circular wavenumber, as opposed to uniform sampling in optical frequency. We further explicate the source of this point spread broadening and simulate its magnitude in aqueous media. We experimentally demonstrate media dispersion compensation in high dispersion glass by choosing sample frequencies at equal intervals of media index of refraction divided by vacuum wavelength, and we recover unbroadened reflections without an additional postprocessing step.
authors.affiliation: Division of Biomedical Engineering, University of Arizona, Tucson 85721, USA. tumlinsonar@cardiff.ac.uk
authors.forename: Alexandre R
authors.initials: AR
authors.lastname: Tumlinson
authors.forename: Bernd
authors.initials: B
authors.lastname: Hofer
authors.forename: Amy M
authors.initials: AM
authors.lastname: Winkler
authors.forename: Boris
authors.initials: B
authors.lastname: Povazay
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Drexler
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Barton
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D016477:Artifacts; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods; D016247:Information Storage and Retrieval; D007368:Interferometry / Q000379:methods / Q000706:statistics & numerical data; D012031:Refractometry / Q000379:methods / Q000706:statistics & numerical data; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D013057:Spectrum Analysis / Q000379:methods; D016008:Statistical Distributions; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000706:statistics & numerical data