title: [A preliminary study of serum free testosterone and testosterone secreting index in men with erectile dysfunction].
abstract: OBJECTIVE
  To observe the changes of serum free testosterone (FT) and testosterone secreting index (TSI) in ED patients, and to assess the contribution of these two indexes to the diagnosis of ED caused by endocrine factors.
  
  
  METHODS
  We studied 120 ED patients and 30 healthy men undergoing pre-marital medical check-up in Jiangsu Province Hospital of TCM by analyzing the scores on erectile function and desire domain in IIEF, testing the serum total testosterone, luteinizing hormone by chemiluminescent enzyme immunoassay (CLIA), measuring free testosterone by radioimmunoassay( RIA), and calculating TSI.
  
  
  RESULTS
  Of the 120 ED patients, 5% and 1538% were below the reference norm of TT and FT values respectively. TT, FT and TSI decreased with age, with statistical with FT and TSI, but not with TT. FT and TSI statistically declined with lower IIEF score on ED domain, but this was not the case with TT. There were no significant differences in TI, FT and TSI among different sexual desire groups the ED patients.
  
  
  CONCLUSIONS
  FT is much more valuable than TF in the diagnosis of ED with hypogonadism. Both FT and TSI are important parameters in assessing the severity of ED.
authors.affiliation: Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China. Xuejg5199@126.com
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Xue
authors.forename: Zong-Lin
authors.initials: ZL
authors.lastname: Lu
authors.forename: Ke-Qin
authors.initials: KQ
authors.lastname: Ning
authors.forename: Ying
authors.initials: Y
authors.lastname: He
authors.forename: Liang-Yu
authors.initials: LY
authors.lastname: Ni
authors.forename: Qing
authors.initials: Q
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Huang
authors.forename: Zhi-Xing
authors.initials: ZX
authors.lastname: Sun
authors.forename: Xin-Fei
authors.initials: XF
authors.lastname: Huang
authors.forename: Yong-Qin
authors.initials: YQ
authors.lastname: She
authors.forename: Liang
authors.initials: L
authors.lastname: Ge
authors.forename: Chun-Bing
authors.initials: CB
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D007172:Erectile Dysfunction / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000097:blood* / Q000378:metabolism
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone