title: Multitracer study in Heidenhain variant of Creutzfeldt-Jakob disease: mismatch pattern of cerebral hypometabolism and perfusion imaging.
abstract: Creutzfeldt-Jakob disease (CJD) is a subacute spongiform encephalopathy. This fatal prion disease is characterized by rapidly progressive dementia with a variety of neurological disorders. Diagnostic methods provided by nuclear medicine might be helpful for evaluation of patients with probable CJD as additional diagnostic tools to MRI and cerebro-spinal fluid evaluation. The experience with FDG-PET and brain perfusion SPECT is presented.
authors.affiliation: Institute of Nuclear Medicine, Wagner-Jauregg Hospital, Linz, Austria. robert.pichler@gespag.at
authors.forename: Robert
authors.initials: R
authors.lastname: Pichler
authors.forename: Ioana
authors.initials: I
authors.lastname: Ciovica
authors.forename: Johanna
authors.initials: J
authors.lastname: Rachinger
authors.forename: Serge
authors.initials: S
authors.lastname: Weiss
authors.forename: Franz T
authors.initials: FT
authors.lastname: Aichner
mesh_terms: D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000000981:diagnostic imaging* / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals / Q000378:metabolism; D012039:Regional Blood Flow; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18