Biomimetic trifunctional organocatalyst showing a great acceleration for the transesterification between vinyl ester and alcohol.
Trifunctional organocatalysts and mimicking the active site of serine hydrolases showed high catalytic activity with up to a 3,700,000-fold acceleration for the acyl-transfer reactions from vinyl trifluoroacetate to alcohol.
Ema
Tadashi
T
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Okayama 700-8530, Japan. ema@cc.okayama-u.ac.jp
Tanida
Daisuke
D
Matsukawa
Tatsuya
T
Sakai
Takashi
T
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D001665:Binding Sites; D040761:Biomimetic Materials / Q000138:chemical synthesis / Q000737:chemistry*; D032701:Biomimetics; D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D006860:Hydrogen Bonding; D008968:Molecular Conformation; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D013890:Thiourea / Q000737:chemistry*; D013997:Time Factors; D014753:Vinyl Compounds / Q000737:chemistry*
D000438:Alcohols; D004952:Esters; D011725:Pyridines; D014753:Vinyl Compounds; C528648:vinyl trifluoroacetate; D013890:Thiourea