Apoptosis of leukocytes as a marker of neutrophil-endotheliocyte interaction in coronary heart disease.
We studied the mechanism of interaction of peripheral blood neutrophils with endothelial cells (expression of cell adhesion molecules and production of NO) and the role of neutrophil apoptosis in the development of endothelial dysfunction. The effects of mitochondrial dysfunction of neutrophils on the development of apoptosis of these cells after their interaction with endothelial cells were analyzed.
Salmina
A B
AB
Department of Biochemistry with a Course of Medical Chemistry, Krasnoyarsk State Medical Academy, Federal Agency for Health Care and Social Development.
Shul'man
V A
VA
Nikulina
S Yu
SY
Trufanova
L V
LV
Fursov
A A
AA
But'yanov
P A
PA
Kuskaev
A P
AP
Bol'shakova
E V
EV
Kotlovskii
M Yu
MY
D017209:Apoptosis; D002450:Cell Communication / Q000502:physiology*; D003327:Coronary Disease / Q000097:blood* / Q000503:physiopathology; D042783:Endothelial Cells / Q000502:physiology*; D006801:Humans; D007962:Leukocytes / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000502:physiology*; D009569:Nitric Oxide / Q000097:blood*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000096:biosynthesis
D019408:Platelet Endothelial Cell Adhesion Molecule-1; D009569:Nitric Oxide