Persistent Bordetella bronchiseptica pneumonia in an immunocompetent infant and genetic comparison of clinical isolates with kennel cough vaccine strains.
An infant who experienced recurrent episodes of respiratory failure received a diagnosis of pertussis on the basis of immunofluorescence testing, but culture revealed macrolide-resistant Bordetella bronchiseptica. Genetic analysis demonstrated that the child was not infected with a kennel cough vaccine strain, although the family's dog had recently been vaccinated. The infection cleared with imipenem therapy.
Rath
Barbara A
BA
Department of Pediatrics, Division of Infectious Diseases, Tulane University Health Sciences Center, New Orleans, Louisiana, USA. Barbara.Rath@gmail.com
Register
Karen B
KB
Wall
Jeffrey
J
Sokol
Dawn M
DM
Van Dyke
Russell B
RB
D000818:Animals; D015373:Bacterial Typing Techniques; D001428:Bacterial Vaccines / Q000145:classification / Q000235:genetics; D001431:Bacteriological Techniques; D001885:Bordetella Infections / Q000382:microbiology; D016950:Bordetella bronchiseptica / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D003371:Cough / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D003470:Culture Media; D004283:Dog Diseases / Q000382:microbiology / Q000517:prevention & control*; D004285:Dogs; D006801:Humans; D007121:Immunocompetence; D007223:Infant; D018410:Pneumonia, Bacterial / Q000382:microbiology*
D001428:Bacterial Vaccines; D003470:Culture Media