Plant-derived compounds in clinical trials.
Plants remain an important source of new drugs, new drug leads and new chemical entities. The plant-based drug discovery resulted mainly in the development of anticancer and anti-infectious agents and continues to contribute to the new leads in clinical trials. A total of 91 plant-derived compounds in clinical trials as of September 2007 are described in this review. A summary of the plant-based drugs launched during 2000-2006 is given.
Saklani
Arvind
A
Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sector-67, SAS Nagar 160062, Punjab, India. asaklani@nicholaspiramal.co.in
Kutty
Samuel K
SK
D002986:Clinical Trials as Topic; D015195:Drug Design; D006801:Humans; D015394:Molecular Structure; D008517:Phytotherapy / Q000379:methods* / Q000639:trends; D028321:Plant Preparations / Q000737:chemistry / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000737:chemistry*; D013997:Time Factors
D028321:Plant Preparations