title: [Comparison of the oncological results of laparoscopic and open surgical total nephroureterectomy].
abstract: OBJECTIVE
  To analyse the medium-term oncological results of total nephroureterectomy for upper tract urothelial tumour according to the surgical approach: laparoscopy or open surgery.
  
  
  METHODS
  Retrospective study including 38 consecutive patients undergoing total nephroureterectomy for upper tract urothelial tumour in our department. Patients were classified into 2 groups according to the surgical approach: Group 1 (19 patients) laparoscopic release of the kidney +/- distal ureter and Group 2 (19 patients) open surgery of the kidney and ureter.
  
  
  RESULTS
  The two groups were comparable in terms of clinical context and histology. The mean follow-up was 27 +/- 22 months (range: 3-77 months). During this follow-up, 9 patients (23.7%) died from progression of their urothelial tumour. A local recurrence was observed in 6 cases (15.8%), a bladder recurrence was observed in 14 cases (36.8%) and metastatic recurrence was observed in 4 cases (11.4%). The operative technique (laparoscopy versus open surgery) did not influence overall survival (p = 0.5339), or local (p = 0.4503), bladder (p = 0.8224) or metastatic (p = 0.8932) recurrence-free survival.
  
  
  CONCLUSIONS
  The medium-term oncological results oflaparoscopic total nephroureterectomy for upper tract urothelial tumour were comparable to those of open surgery.
authors.affiliation: Clinique Urologique, Hôtel-Dieu, Nantes, France. brice.muller@tele2.fr
authors.forename: Brice
authors.initials: B
authors.lastname: Müller
authors.forename: Guillaume
authors.initials: G
authors.lastname: Braud
authors.forename: Xavier
authors.initials: X
authors.lastname: Tillou
authors.forename: Georges
authors.initials: G
authors.lastname: Karam
authors.forename: Olivier
authors.initials: O
authors.lastname: Bouchot
authors.forename: Jérôme
authors.initials: J
authors.lastname: Rigaud
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000556:secondary / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D016609:Neoplasms, Second Primary / Q000453:epidemiology; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014513:Ureter / Q000601:surgery*; D014516:Ureteral Neoplasms / Q000601:surgery*