title: Cytokine elevations in acute coronary syndrome and ovarian cancer: a mechanism for the up-regulation of the acute phase proteins in these different disease etiologies.
abstract: OBJECTIVE
  To identify if a common set of cytokines is elevated in both ovarian cancer and acute coronary syndrome (ACS).
  
  
  METHODS
  A cytokine array (Randox Ltd) was measured in healthy women (n=33), women with ACS (n=21) and ovarian cancer (n=45).
  
  
  RESULTS
  Women with ACS or ovarian cancer had higher concentrations of IL-6, IL-8, VEGF, MCP-1, and EGF as compared to healthy volunteers.
  
  
  CONCLUSIONS
  Common cytokine elevations are present in both ACS and ovarian cancer.
authors.affiliation: Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. kavsakp@mcmaster.ca
authors.forename: Peter A
authors.initials: PA
authors.lastname: Kavsak
authors.forename: Agnes
authors.initials: A
authors.lastname: Lee
authors.forename: Hal
authors.initials: H
authors.lastname: Hirte
authors.forename: Ed
authors.initials: E
authors.lastname: Young
authors.forename: Jack
authors.initials: J
authors.lastname: Gauldie
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000209:etiology; D000209:Acute-Phase Proteins / Q000096:biosynthesis*; D000328:Adult; D016207:Cytokines / Q000096:biosynthesis* / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood* / Q000209:etiology; D015854:Up-Regulation / Q000502:physiology*
chemical_list: D000209:Acute-Phase Proteins; D016207:Cytokines