Growth hormone therapy in boy with panhypopituitarism may induce pilomatricoma recurrence: case report.
Pilomatricoma is usually a solitary subcutaneous nodule. Recurrence of the nodule after surgical excision is very rare. Pilomatricoma occurrence in patients with growth hormone (GH) deficiency has not been reported, yet. We report a 14-year-old boy with pilomatricoma and panhypopituitarism. After GH therapy had been started, we observed two relapses of previously completely excised pilomatricoma in the same location and a new pilomatricoma formation on the chin.
Oswiecimska
Joanna M
JM
Department of Paediatrics, Silesian Medical University in Zabrze, Poland. smina@poczta.onet.pl
Ziora
Katarzyna T
KT
Ziora
Karolina N
KN
Pindycka-Piaszczynska
Malgorzata
M
Zajecki
Wojciech
W
Pikiewicz-Koch
Anna
A
Stojewska
Małgorzata
M
D000293:Adolescent; D004305:Dose-Response Relationship, Drug; D013006:Growth Hormone / Q000009:adverse effects* / Q000627:therapeutic use*; D006201:Hair Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007018:Hypopituitarism / Q000188:drug therapy*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000139:chemically induced* / Q000175:diagnosis; D018296:Pilomatrixoma / Q000139:chemically induced* / Q000175:diagnosis; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000175:diagnosis
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone