Relationship between thyroid status and renal function in a general population of unselected outpatients.
OBJECTIVE
To investigate the relationship between thyroid and kidney function.


METHODS
13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory.


RESULTS
When compared with euthyroid subjects, those with TSH <0.2 mIU/L and >2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR.


CONCLUSIONS
A mutual relationship was observed between kidney and thyroid status.
Lippi
Giuseppe
G
Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università di Verona, Italy. ulippi@tin.it
Montagnana
Martina
M
Targher
Giovanni
G
Salvagno
Gian Luca
GL
Guidi
Gian Cesare
GC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care / Q000379:methods; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000502:physiology*; D007677:Kidney Function Tests / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013961:Thyroid Gland / Q000502:physiology*; D013972:Thyrotropin / Q000097:blood
D013972:Thyrotropin; D003404:Creatinine