[Effects of scalp catgut embedding on SOD, NO, MDA in the rat with Parkinson's disease].
OBJECTIVE
To explore the mechanism of scalp catgut embedding for treatment of Parkinson's disease.


METHODS
Parkinson's disease model rats were prepared, and randomly divided into a model group, scalp acupuncture group, medication group, with a control group set up. The scalp acupuncture group were treated with catgut embedding at "the chorea-trembling conroued area" lateral to "Baihui" (GV 20) and the medication group with intra-gastric perfusion of L-dopa suspension. After treatment for 30 days, behavior indexes were investigated and malondialdehyde (MDA) and nitric oxide (NO) contents and superoxide dismutase (SOD) activity in the brain were detected.


RESULTS
MDA content in the brain of the model rats were significantly decreased (P < 0.01), NO level significantly increased (P < 0.05) by scalp catgut embedding, with no significant change of SOD activity (P > 0.05); and the behavior indexes and tissue and form of the brain had significant improvement.


CONCLUSIONS
Scalp catgut embedding has regulative action on anti-oxidant enzyme system in the Parkinson's disease rats, has significant improvement of cells, tissues and form of the brain.
Xie
Xiao-Xia
XX
Gansu Hospital of Health Care of Cadres, Lanzhou 730020, China. xie6761@126.com
Kou
Suo-Tang
ST
Pu
Zhi-Hong
ZH
Hou
Chun-Ying
CY
Tian
Yong-Ping
YP
D015670:Acupuncture Therapy / Q000379:methods*; D000818:Animals; D002398:Catgut; D005260:Female; D008297:Male; D008315:Malondialdehyde / Q000032:analysis*; D009569:Nitric Oxide / Q000032:analysis*; D010300:Parkinson Disease / Q000378:metabolism / Q000628:therapy*; D051381:Rats; D017208:Rats, Wistar; D012535:Scalp; D013482:Superoxide Dismutase / Q000378:metabolism*
D009569:Nitric Oxide; D008315:Malondialdehyde; D013482:Superoxide Dismutase