title: A case of chylothorax treated curatively with Sapylin, a streptococcus preparation.
abstract: Chylothorax is an uncommon disease where fatty fluid accumulates within the chest cavity. Conservative management, including repeated thoracentesis or pleurodesis, seems to be suitable to most cases. Herein, we present a case of efficacious pleurodesis by intrapleural injection of Sapylin, a streptococcus preparation, for the treatment of chylothorax. A 52-year-old non-smoking female farmer was diagnosed as idiopathic chylothorax after we ruled out possible causes including chest trauma, lymphoma, lung cancer, filariasis, tuberculosis, and etc. Two-time intra-thoracic injection of 3 Klinische Einheit (KE) Sapylin achieved rapid and effective control of chylothorax with no severe side effects. Sapylin may facilitate pleurodesis by producing a strong inflammatory response.
authors.affiliation: Department of Respiratory Diseases, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Zhi-hao
authors.initials: ZH
authors.lastname: Xu
authors.forename: Chun-fu
authors.initials: CF
authors.lastname: Wang
authors.forename: Yue-qin
authors.initials: YQ
authors.lastname: Zhang
authors.forename: Hua-hao
authors.initials: HH
authors.lastname: Shen
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
mesh_terms: D001428:Bacterial Vaccines / Q000627:therapeutic use*; D001688:Biological Products / Q000627:therapeutic use*; D002916:Chylothorax / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D013291:Streptococcus / Q000737:chemistry*; D014057:Tomography, X-Ray Computed
chemical_list: D001428:Bacterial Vaccines; D001688:Biological Products; C569879:streptococcal preparation 722