title: Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes.
abstract: Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.
authors.affiliation: Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate, N-5008 Bergen, Norway. par.engstrom@bccs.uib.no
authors.forename: Pär G
authors.initials: PG
authors.lastname: Engström
authors.forename: David
authors.initials: D
authors.lastname: Fredman
authors.forename: Boris
authors.initials: B
authors.lastname: Lenhard
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D018507:Gene Expression Regulation, Developmental; D050437:Genes, Developmental; D005809:Genes, Regulator; D016678:Genome; D006801:Humans; D020407:Internet; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D020506:Untranslated Regions / Q000235:genetics*
chemical_list: D020506:Untranslated Regions