[HIV mother to child transmission: report of nine Cuban fatal cases in ten years].
Vertical transmission of HIV infection constitutes one of the most sensitive pillars of the current pandemic of this disease. This article carries out a report of the nine Cuban children who acquired this way the infection and died between 1986 and 2006. Prophylactic management of the cases and the clinical and anatomic pathological manifestations of those in whom autopsy was performed are described. The average gestational age was of 37.6 weeks, four of the pregnancies were captured late. Six children were born by caesarean section and in all transmission were presumably intrauterine. The average birth weight was 2786 grams. Four mother-sibling binomial received prophylaxis with AZT. The autopsy was carried out only in 4 children.
González N
Ida
I
Instituto de Medicina Tropical Pedro Kouri, La Habana, Cuba.
Díaz-Jidy
Manuel
M
Berdasquera C
Denis
D
Toledo R
M Eugenia
ME
Pérez A
Jorge
J
D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D003462:Cuba; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000473:pathology / Q000635:transmission*; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012189:Retrospective Studies; D015215:Zidovudine / Q000627:therapeutic use*
D019380:Anti-HIV Agents; D015215:Zidovudine