[Studies on chemical constituents in the buds of Tussilago farfara].
OBJECTIVE
To study the chemical constituents in the buds of Tussilago farfara.


METHODS
The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.


RESULTS
Eleven compounds were obtained and identified as methyl 3, 4-O-dicaffeoylquinate (1), methyl 3, 5-O-dicaffeoylquinate (2), methyl 4, 5-O-dicaffeoylquinate (3), 3, 5-O-dicaffeoylquinic acid (4), methyl 3-O-caffeoylquinate (5), 3-O-caffeoylquinic acid (6), hyperoside (7), rutin (8), kaempferol 3-O-beta-D-glucopyranoside (9), quercetin (10), and kaempferol (11).


CONCLUSIONS
Compounds 2-5 were isolated from the genus for the first time.
Liu
Yu-feng
YF
Department of Natural Medicines, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Yang
Xiu-wei
XW
Wu
Bin
B
D035264:Flowers / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D011801:Quinic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D012431:Rutin / Q000737:chemistry / Q000302:isolation & purification; D031207:Tussilago / Q000737:chemistry*
C472707:caffeoylquinic acid; C538691:methyl 3, 5-O-dicaffeoylquinate; C538692:methyl 3-O-caffeoylquinate; D011801:Quinic Acid; D012431:Rutin; C021304:hyperoside; D011794:Quercetin