Predominance of rotavirus P[4]G2 in a vaccinated population, Brazil.
We identified 21 rotaviruses in 129 patients with diarrhea in a Brazilian city with high rotavirus vaccine coverage. All rotaviruses were genotype P[4]G2 with 1 mixed infection with P[NT]G9. Although virus predominance could have occurred randomly, the vaccine may be less protective against P[4]G2. Prospective surveillance is urgently needed.
Gurgel
Ricardo Q
RQ
Federal University of Sergipe, Aracaju, Brazil. ricardoqg@infonet.com.br
Cuevas
Luis E
LE
Vieira
Sarah C F
SC
Barros
Vanessa C F
VC
Fontes
Paula B
PB
Salustino
Eduardo F
EF
Nakagomi
Osamu
O
Nakagomi
Toyoko
T
Dove
Winifred
W
Cunliffe
Nigel
N
Hart
Charles A
CA
D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004403:Dysentery / Q000276:immunology / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D032541:Mass Vaccination; D012401:Rotavirus / Q000145:classification / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology / Q000276:immunology* / Q000821:virology*; D022243:Rotavirus Vaccines / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000276:immunology*
C492457:RIX4414 vaccine; D022243:Rotavirus Vaccines; D014613:Vaccines, Attenuated