Duration of antibody responses after severe acute respiratory syndrome.
Among 176 patients who had had severe acute respiratory syndrome (SARS), SARS-specific antibodies were maintained for an average of 2 years, and significant reduction of immunoglobulin G-positive percentage and titers occurred in the third year. Thus, SARS patients might be susceptible to reinfection >or=3 years after initial exposure.
Wu
Li-Ping
LP
Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, People's Republic of China.
Wang
Nai-Chang
NC
Chang
Yi-Hua
YH
Tian
Xiang-Yi
XY
Na
Dan-Yu
DY
Zhang
Li-Yuan
LY
Zheng
Lei
L
Lan
Tao
T
Wang
Lin-Fa
LF
Liang
Guo-Dong
GD
D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D000917:Antibody Formation / Q000276:immunology*; D002681:China; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008137:Longitudinal Studies; D045473:Severe acute respiratory syndrome-related coronavirus / Q000276:immunology*; D045169:Severe Acute Respiratory Syndrome / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G