An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae).
The limonoid derivative, methyl uguenenoate, the azole, uguenenazole, and the amide, uguenenonamide, together with the known furoquinoline alkaloids flindersiamine and maculosidine, and syringaldehyde have been isolated from the root of the East African Rutaceae Vepris uguenensis. While methyl uguenenoate and the furoquinoline alkaloids displayed mild antimalarial activity, the azole and amide were completely inactive.
Cheplogoi
Peter K
PK
School of Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa.
Mulholland
Dulcie A
DA
Coombes
Philip H
PH
Randrianarivelojosia
Milijaona
M
D000577:Amides / Q000737:chemistry*; D001393:Azoles / Q000737:chemistry*; D036701:Limonins / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*
D000577:Amides; D001393:Azoles; D036701:Limonins; C532543:methyl uguenenoate; C532545:uguenenazole; C532546:uguenenonamide