[Changes of QT-interval duration in children and adolescents suffering from type 1 diabetes mellitus].
We measured QT interval in 43 children and adolescents with type 1 diabetes mellitus and studied its dependence on age, disease duration, metabolic control, and dose of insulin. Control group consisted of 37 healthy children and adolescents. Duration of QT during 24 hours was longer in patients as compared with controls. Patients also more often had prolonged QT. Both in patients and controls there was no relation between age and QRc. There was no interrelationship in patients between glycated hemoglobin, diabetes duration and lenght of QTc. Moderate correlation was revealed between dose of insulin administered in 24 hours and length of QTc.
Riabykina
G V
GV
Laptev
D N
DN
Seid-Guseĭnov
A A
AA
D000293:Adolescent; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D015716:Electrocardiography, Ambulatory; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000378:metabolism; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007328:Insulin / Q000008:administration & dosage; D008297:Male; D012720:Severity of Illness Index
D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin