title: Comparative study between target-controlled-infusion and continuous-infusion anesthesia in dogs treated with methotrimeprazine and treated with propofol and remifentanil.
abstract: OBJECTIVE
  To compare two propofol infusion techniques in bitches subjected to ovary histerectomy by estimating the efficiency of the propofol target-dose, evaluating the cardiorespiratory and hemogasimetric attributes, and the bispectral scale index (BIS) as well as the recovery period characteristics.
  
  
  METHODS
  Twenty anesthetized bitches were divided into two groups of 10 each (G1, G2). Animals of G1 were pre-treated with methotrimeprazine and anesthetized with target-controlled propofol infusion by means of a Harvard infusion pump combined to remifentanil through a syringe pump.
  
  
  RESULTS
  Bradycardia and light hypotension, hemogasimetric and respiratory stability besides a good myorelaxation, more evident during continuous infusion and good hypnosis.
  
  
  CONCLUSIONS
  Dosis used in both techniques, after methotrimeprazine pre-treatment and combined to the opioid, were efficient for the surgery. The target-controlled anesthesia required a smaller anesthetic consumption (propofol) with faster recovery periods.
authors.affiliation: Faculty of Medicine of Botucatu, UNESP, São Paulo, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Hatschbach
authors.forename: Fernando do Carmo
authors.initials: Fdo C
authors.lastname: Silva
authors.forename: Suzane Lílian
authors.initials: SL
authors.lastname: Beier
authors.forename: Alfredo Feio da Maia
authors.initials: AF
authors.lastname: Lima
authors.forename: Flávio
authors.initials: F
authors.lastname: Massone
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000771:Anesthesia, Intravenous / Q000379:methods*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000818:Animals; D004285:Dogs; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D007260:Infusion Pumps; D008728:Methotrimeprazine / Q000008:administration & dosage; D010052:Ovariectomy; D010880:Piperidines / Q000008:administration & dosage; D015742:Propofol / Q000008:administration & dosage; D011897:Random Allocation; D000077208:Remifentanil; D012119:Respiration / Q000187:drug effects
chemical_list: D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D010880:Piperidines; D008728:Methotrimeprazine; D000077208:Remifentanil; D015742:Propofol