Can surgeons improve survival in stage IV melanoma?
Successful systemic management of stage IV melanoma continues to be elusive because of the paucity of effective therapies. This has fueled the continued interest in surgical resection. Several single-institution studies and a current, large, multi-institutional phase III trial have demonstrated a survival benefit for patients who underwent surgical resection for melanoma metastases. Incorporating these results into new approaches using multimodality treatment may enhance survival in patients with stage IV melanoma.
Mosca
Paul J
PJ
Department of Surgery, Lehigh Valley Hospital, Allentown, PA, USA.
Teicher
Erik
E
Nair
Suresh P
SP
Pockaj
Barbara A
BA
D002986:Clinical Trials as Topic; D006801:Humans; D008545:Melanoma / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery*; D020360:Neoadjuvant Therapy; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*; D016019:Survival Analysis