Comparative results of central corneal thickness measurements in primary open-angle glaucoma, pseudoexfoliation glaucoma, and ocular hypertension.
OBJECTIVE
As clinical measurements of corneal thickness have become widely available, several studies found a positive correlation between central corneal thickness and applanation tonometry measurements. This study evaluated central corneal thickness in different types of glaucoma.


METHODS
An observational cross-sectional study assessed central corneal thickness using a specular microscope in the following groups of patients: 60 eyes with primary open-angle glaucoma, 50 eyes with pseudoexfoliation glaucoma, 50 eyes with ocular hypertension, and 60 eyes without glaucoma or ocular hypertension (control group).


RESULTS
Central corneal thickness was significantly thinner in cases with pseudoexfoliation glaucoma (P < .0001) and significantly thicker in cases with ocular hypertension (P< .0001).


CONCLUSIONS
These results agree with the literature, strengthening the position that central corneal thickness varies in different types of glaucoma and, therefore, is a parameter that should be taken under consideration, especially when evaluating cases of pseudoexfoliative glaucoma and ocular hypertension.
Gorezis
Spiridon
S
Ophthalmology Department, University of Ioannina, Ioannina, Greece.
Christos
Gartzos
G
Stefaniotou
Maria
M
Moustaklis
Kostantinos
K
Skyrlas
Aggelos
A
Kitsos
Georgios
G
D000886:Anthropometry; D001837:Body Weights and Measures; D003315:Cornea / Q000473:pathology*; D003430:Cross-Sectional Studies; D017889:Exfoliation Syndrome / Q000175:diagnosis*; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis; D014065:Tonometry, Ocular