Balloon cells and dysmorphic neurons in the hippocampus associated with epileptic amnesic syndrome: a case report.
Recently, we encountered a 39-year-old woman with typical epileptic amnesic syndrome. The patient underwent right anterior temporal lobectomy, which removed the right hippocampus. The patient's resected hippocampus showed typical histological features of Ammon's horn sclerosis (AHS) with dysmorphic neurons. In addition, the prominent balloon cells, admixed with dysmorphic neurons, were noted in the hippocampus. To our knowledge, this is the first reported case showing AHS with balloon cells. The presence of balloon cells reinforces the hypothesis that AHS itself might be a maldevelopment disorder.
Kim
Se Hoon
SH
Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea.
Cho
Yang-Je
YJ
Seok Kim
Hyung
H
Heo
Kyoung
K
Lee
Min-Cheol
MC
Lee
Byung-In
BI
Seung Kim
Tai
T
Woo Chang
Jin
J
D000328:Adult; D020324:Amnesia, Anterograde / Q000473:pathology; D038481:Anterior Temporal Lobectomy; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000473:pathology* / Q000601:surgery; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D005682:Gadolinium; D006624:Hippocampus / Q000002:abnormalities / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D054220:Malformations of Cortical Development / Q000473:pathology* / Q000601:surgery; D009474:Neurons / Q000473:pathology*; D012598:Sclerosis / Q000473:pathology; D014743:Videotape Recording
D005682:Gadolinium