title: Changes in the urinary excretion of beta2-microglobulin (beta 2MG) and N-acetyl-beta-D-glucosaminidase (NAG) during treatment for lupus nephritis.
abstract: Tubulointerstitial involvement in the kidneys is frequently found but it is a less emphasized feature of lupus nephritis (LN). Recent studies have shown increases in the urinary excretion of beta2-microglobulin (beta 2MG) and N-acetyl-beta-D-glucosaminidase (NAG), which are considered to indicate the presence of tubulointerstitial damage, particularly in cases of LN. However, the changes in these urinary parameters during the clinical course of LN have not yet been fully clarified. In this report, we describe the changes in the urinary excretion of beta 2MG and NAG during immunosuppressive treatment combined with double filtration plasmapheresis in a case of LN.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Masuda
authors.forename: Tetsu
authors.initials: T
authors.lastname: Akimoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ando
authors.forename: Takahisa
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Daishi
authors.initials: D
authors.lastname: Meguro
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Muto
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Ueda
authors.forename: Wako
authors.initials: W
authors.lastname: Yumura
authors.forename: Eiji
authors.initials: E
authors.lastname: Kusano
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine*; D000368:Aged; D006801:Humans; D008181:Lupus Nephritis / Q000628:therapy* / Q000652:urine*; D008297:Male; D001613:beta 2-Microglobulin / Q000652:urine*
chemical_list: D001613:beta 2-Microglobulin; D000118:Acetylglucosaminidase