Smallpox virus resequencing GeneChips can also rapidly ascertain species status for some zoonotic non-variola orthopoxviruses.
We recently developed a set of seven resequencing GeneChips for the rapid sequencing of Variola virus strains in the WHO Repository of the Centers for Disease Control and Prevention. In this study, we attempted to hybridize these GeneChips with some known non-Variola orthopoxvirus isolates, including monkeypox, cowpox, and vaccinia viruses, for rapid detection.
Sulaiman
Irshad M
IM
Division of Scientific Resources, National Center for Preparedness, Detection and Control of Infectious Diseases, Coordinating Center for Infection Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. ISulaiman@cdc.gov
Sammons
Scott A
SA
Wohlhueter
Robert M
RM
D000818:Animals; D015608:Cowpox virus / Q000145:classification / Q000235:genetics; D006801:Humans; D008993:Monkeypox virus / Q000145:classification / Q000235:genetics; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D018155:Orthopoxvirus / Q000145:classification* / Q000235:genetics*; D011213:Poxviridae Infections / Q000821:virology; D017422:Sequence Analysis, DNA; D013045:Species Specificity; D013997:Time Factors; D014616:Vaccinia virus / Q000145:classification / Q000235:genetics; D012901:Variola virus / Q000145:classification / Q000235:genetics*; D014773:Virology / Q000379:methods*; D015047:Zoonoses / Q000821:virology*