title: Cholesterol granuloma of the breast with unusual ossification features (osseous metaplasia).
abstract: Cholesterol granuloma of the breast is a rare benign condition that can be mistaken for breast cancer. We present a case of a 42-year-old woman who presented with a 1-year history of asymptomatic palpable nodule in the upper external quadrant of the right breast. Mammography and ultrasonography suggested carcinoma, but excisional biopsy revealed cholesterol granuloma with unusual osseous metaplasia. Although reported to occur more frequently in the middle ear and mastoid process, we believe that better awareness of this rare benign condition is most important to avoid misdiagnosis and unnecessary surgery.
authors.affiliation: Department of Pathology, Medical Faculty, Federico II University, Naples, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Garofalo
authors.forename: Carmela
authors.initials: C
authors.lastname: Casolino
authors.forename: Antonello
authors.initials: A
authors.lastname: Accurso
authors.forename: Jessica
authors.initials: J
authors.lastname: Falleti
mesh_terms: D000328:Adult; D001706:Biopsy; D001941:Breast Diseases / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D002784:Cholesterol; D003951:Diagnostic Errors / Q000517:prevention & control*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000473:pathology*; D006801:Humans; D008327:Mammography; D008679:Metaplasia; D009999:Ossification, Heterotopic; D016217:Ultrasonography, Mammary
chemical_list: D002784:Cholesterol