title: Case of cheilitis granulomatosa associated with apical periodontitis.
abstract: The etiology of cheilitis granulomatosa is unknown. In some cases, rapid improvement and/or complete elimination of swelling of the lips after dental treatment has been reported. Here, we describe another case of improvement following dental treatment. A 57-year-old woman had developed asymptomatic swelling of the lower lip 2 months previously. Histological examination revealed non-caseous giant cell granulomas. Neither facial nerve palsy nor fissuring of the tongue was present. Patch testing for metal allergy revealed only mild irritation to zinc ion. Although topical corticosteroid ointment and oral tranilast for 4 months were ineffective, rapid and remarkable improvement of the swelling was noted soon after treatment of two lesions of apical periodontitis. Thorough examination for foci of infection is necessary when treating a patient with cheilitis granulomatosa.
authors.affiliation: Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kawakami
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Fukai
authors.forename: Junko
authors.initials: J
authors.lastname: Sowa
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Ishii
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Teramae
authors.forename: Koutetsu
authors.initials: K
authors.lastname: Kanazawa
mesh_terms: D005260:Female; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D010485:Periapical Periodontitis / Q000150:complications* / Q000628:therapy