Progesterone receptor +331G/A polymorphism in endometriosis and deep-infiltrating endometriosis.
In this study, we sought to examine the association between P receptor +331G/A polymorphism and endometriosis. We excluded any relationship between endometriosis in general and the P receptor +331G/A polymorphism but found a significant association with deep-infiltrating endometriosis, supporting a potential role of this variant in the P receptor-dependent invasive behavior of endometrial cells.
Gentilini
Davide
D
Molecular Biology Laboratory, Istituto Auxologico Italiano, Milan, Italy.
Vigano
Paola
P
Carmignani
Luca
L
Spinelli
Matteo
M
Busacca
Mauro
M
Di Blasio
Anna Maria
AM
D004715:Endometriosis / Q000145:classification / Q000453:epidemiology* / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D007558:Italy / Q000453:epidemiology; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D015995:Prevalence; D011980:Receptors, Progesterone / Q000235:genetics*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors
D011980:Receptors, Progesterone