[Sentinel lymph node mapping in colorectal cancer: study of 45 cases].
OBJECTIVE
To discuss the sentinel lymph node (SLN) mapping technique in colorectal cancer and its feasibility and utility.


METHODS
The dye lymphazurin was injected subserosally around the tumor during operation in 43 colorectal cancer, 20 males and 25 females, aged 49.5 (27 - 72) so as to find the SLNs. Fast-frozen pathology and routine pathology were performed too.


RESULTS
SLN was successfully identified in 42 of the 45 patients, with a successful biopsy rate of 93.3%. In these 45 patients, there were 250 lymph nodes examined, of which 52 nodes were identified as SLNs. The sensitivity was 90.4% (20/22), the specificity was 95.2% [(20 + 20)/42], and the false negative rate was 15% (3/20).


CONCLUSIONS
SLN mapping in colorectal cancer plays an important role in diagnosing metastasis of lymph nodes, and can be used to direct the clinical surgery.
Zhang
Yang-de
YD
National Hepatobiliary & Enteric Surgery Research Center, Central South University, Changsha 410008, China.
Tian
Bu-Ning
BN
Li
Hao
H
Zhai
Deng-Gao
DG
D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012394:Rosaniline Dyes / Q000008:administration & dosage; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*
D012394:Rosaniline Dyes; C025484:iso-sulfan blue