Sarcomatoid collecting-duct carcinoma of the kidney.
Collecting duct carcinoma is a distinct entity among renal cell carcinoma, which is characterized by an aggressive behavior. Sarcomatoid variants of this tumor are rarely described. We report the case of a 62-year-old woman who presented with a left kidney tumor. A radical nephrectomy was performed. The tumor was firm with a white appearance, located in the medulla with infiltrating margins. Pathological examination showed a biphasic tumor with carcinomatous areas consisting of a collecting-duct carcinoma and sarcomatous areas with malignant fibrous histiocytoma-like appearance. Immunohistochemical studies confirmed the diagnosis of sarcomatoid collecting-duct carcinoma. The patient died 8 months after the diagnosis.
Charfi
Slim
S
Department of Pathology, University Hospital Habib Bourguiba, Sfax, Tunisia. charfislim@gmail.com
Ayadi
Lobna
L
Ellouze
Sameh
S
Khabir
Abdelmajid
A
Chtourou
Imen
I
Gouiaa
Naourez
N
Bahri
Ibticem
I
Sellami-Boudawara
Tahya
T
D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology*; D007685:Kidney Tubules, Collecting / Q000473:pathology*; D008875:Middle Aged; D012509:Sarcoma / Q000473:pathology