title: [Functional MRI for planning in neurosurgery].
abstract: Beside structural images from CT and MR, functional data about localization of brain activations with different tasks becomes more and more important for presurgical planning. With this method, it's possible to depict mainly primary sensory and motoric areas, but also higher functions like speech and memory. To judge this information adequately, one has to be aware of the variability of activation pattern dependent on chosen threshold. Especially, the absence of such activation at a given location does not necessary mean that this area has no function. The reliability of a measurement strongly depends on efficiency of experimental design and cooperation of the patient. Therefore, short and easy tasks which can be performed in a block design should be preferred. Information about localization of functions determined by fMRI can mainly be used for presurgical planning. Intraoperative usage in the navigation system is problematic due to the brain shift. Therefore, intraoperative imaging together with dynamic adaptation using nonlinear deformation algorithms may improve the value of fMRI in the future.
authors.affiliation: Sektion für Experimentelle Kernspinresonanz des ZNS, Abteilung Neuroradiologie, Universitätsklinikum Tübingen. michael.erb@med.uni-tuebingen.de
authors.forename: Michael
authors.initials: M
authors.lastname: Erb
authors.forename: Ralf
authors.initials: R
authors.lastname: Saur
mesh_terms: D001921:Brain / Q000473:pathology; D001931:Brain Mapping; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed