[Semen biochemical markers and their significance in the patients with premature ejaculation].
OBJECTIVE
To detect the changes of biochemical markers in the semen of premature ejaculation patients and investigate the correlation of the markers with premature ejaculation.


METHODS
Fifty-six premature ejaculation patients and 60 males with normal sexual behavior were enrolled in this experiment. Acid phosphatase, alpha- glucosidase and fructose were assayed by the methods of glucose oxidase, disodium phenyl phosphate and disodium phenyl phosphate respectively.


RESULTS
The contents of acid phosphatase, alpha-glucosidase and fructose were (36.37 +/- 31.33) U/ml, (39.97 +/- 22. 09) U/ml and (3.40 +/- 1.92) mg/ml in the premature ejaculation patients and (54. 27 +/- 20. 96) U/ml, (55.71 +/- 16.19) U/ml and (2.55 +/- 1.12) mg/ml in the normal control, respectively, with significant differences in the former two markers between the two groups. The rate of the abnormal content of both acid phosphatase and alpha- glucosidase was 31% and 13% (P < 0.05) , while that of the normal content of the three markers was 10% and 33% in premature ejaculation group and the control, respectively (P < 0. 05 ).


CONCLUSIONS
The abnormality of both acid phosphatase and alpha-glucosidase is one of the causes of premature ejaculation. Because acid phosphatase and alpha- glucosidase reflect the functions of the prostate and epididymis, we should pay attention to the status of these two organs in the treatment of premature ejaculation.
Yao
Bing
B
PLA Research Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu 210002, China. yaobingliang@yahoo.com.cn
Li
Xi-Ying
XY
Zhao
Zhi-Ming
ZM
Cai
Yong-Lin
YL
Shao
Yong
Y
Ge
Yi-Feng
YF
Cui
Ying-Xia
YX
Xia
Xin-Yi
XY
Huang
Yu-Feng
YF
D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D015415:Biomarkers / Q000032:analysis*; D004542:Ejaculation / Q000502:physiology*; D005632:Fructose / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012661:Semen / Q000737:chemistry*; D012735:Sexual Dysfunction, Physiological / Q000378:metabolism* / Q000503:physiopathology; D000520:alpha-Glucosidases / Q000032:analysis
D015415:Biomarkers; D005632:Fructose; D000135:Acid Phosphatase; D000520:alpha-Glucosidases