title: Endocrine disruptors affect developmental programming of HOX gene expression.
abstract: HOX gene expression determines the differential developmental identity of the Müllerian duct. Diethylstilbestrol and several environmental xenoestrogens disrupt the development of the female reproductive tract by altering HOX gene expression, leading to structural and functional defects.
authors.affiliation: Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520, USA. hugh.taylor@yale.edu
authors.forename: Hugh S
authors.initials: HS
authors.lastname: Taylor
mesh_terms: D000818:Animals; D052244:Endocrine Disruptors / Q000633:toxicity*; D005260:Female; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects*; D005836:Genitalia, Female / Q000002:abnormalities* / Q000502:physiology; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans
chemical_list: D052244:Endocrine Disruptors; D018398:Homeodomain Proteins