A 46XX disorder of sex development with a prostate gland and increased level of prostate-specific antigen.
A 5-year-old child with precocious puberty and complete masculinization of the genitalia was diagnosed to have 21-hydroxylase deficiency. The patient was also found to have a prostate gland and increased prostate-specific antigen. The presence of a prostate and its relation to prostate-specific antigen and prostate adenocarcinoma are discussed in the light of the relevant literature.
Yeşilkaya
Ediz
E
Department of Pediatric Endocrinology, Gazi University Medical School, Ankara, Turkey. eyesilkaya@yahoo.co.uk
Cinaz
Peyami
P
Bideci
Aysun
A
Camurdan
Orhun
O
Boyraz
Mehmet
M
D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D002675:Child, Preschool; D012734:Disorders of Sex Development / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011467:Prostate / Q000002:abnormalities* / Q000503:physiopathology; D017430:Prostate-Specific Antigen; D011629:Puberty, Precocious; D046468:Sexual Development
D017430:Prostate-Specific Antigen