Giant cell reparative granuloma of the cranial vault-case report and review of literature.
BACKGROUND
Giant cell reparative granuloma is a condition commonly found in the facial bones. It has been reported in the skull bones, predominantly the bones comprising the skull base. Giant cell reparative granuloma of the cranial vault is exceedingly rare. Its distinction from a neoplastic lesion is difficult clinically and radiologically.


METHODS
Only the third case of a GCRG of the skull vault, the first in an adult, is described. Its pathophysiology and differential diagnoses influencing management are discussed.


CONCLUSIONS
It is not possible to diagnose this condition definitively on a clinical or radiologic basis, and given its differential diagnoses, an excision biopsy should be offered.
Mukerji
Nitin
N
Department of Neurosurgery, St Bartholomew's and The Royal London Hospital, E1 1BB Whitechapel, London. nitinmukerji@hotmail.com
Willmott
Henry
H
Joy
Anthony
A
Sutter
Reto
R
Wadley
John
J
D000328:Adult; D003399:Craniotomy / Q000379:methods; D004388:Dura Mater / Q000473:pathology / Q000601:surgery; D005260:Female; D006101:Granuloma, Giant Cell / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D016489:Head Injuries, Closed / Q000150:complications*; D006801:Humans; D010294:Parietal Bone / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology*; D019736:Prostheses and Implants; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000295:instrumentation / Q000379:methods; D012886:Skull / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology*; D014025:Titanium / Q000627:therapeutic use; D016896:Treatment Outcome
D014025:Titanium