title: [Lactic acidosis associated with propofol during general anaesthesia for neurosurgery].
abstract: Propofol infusion syndrome (PRIS) is a new clinical entity reported in critically ill patients. Lactic acidosis, cardiac failure and rhabdomyolysis are the features. Lactic acidosis related to short-term propofol administration has been described during general anaesthesia. Lactic acidosis could be an early marker of PRIS. We report here a case of very early lactic acidosis in a 66-year-old-man receiving propofol during a neurosurgery. The outcome was good after discontinuation of propofol.
authors.affiliation: Département d'anesthésie-réanimation, HIA Sainte-Anne, boulevard Sainte-Anne, 83800 Toulon, France. bordes.julien@neuf.fr
authors.forename: J
authors.initials: J
authors.lastname: Bordes
authors.forename: E
authors.initials: E
authors.lastname: Meaudre
authors.forename: Y
authors.initials: Y
authors.lastname: Asencio
authors.forename: A
authors.initials: A
authors.lastname: Montcriol
authors.forename: E
authors.initials: E
authors.lastname: Kaiser
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced*; D000368:Aged; D000768:Anesthesia, General / Q000379:methods; D018686:Anesthetics, Intravenous / Q000009:adverse effects*; D001932:Brain Neoplasms / Q000601:surgery*; D005909:Glioblastoma / Q000601:surgery*; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced; D008297:Male; D015742:Propofol / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol