title: Endoclipping-assisted resection of large colorectal polyps.
abstract: BACKGROUND
  The use of endoclipping may minimize the risk of bleeding after endoscopic polypectomy of large pedunculated polyps. The aim of this study was to assess the safety and efficacy of endoclipping of the stalk before resection of large pedunculated colorectal polyps, drawing particular attention to the cases in which the use of this method could be very useful.
  
  
  METHODS
  This retrospective study included 17 patients [10 men, 7 women; median age: 62 y (range 38 to 79)] with 18 large pedunculated colorectal polyps, who underwent endoclipping-assisted endoscopic polypectomy between March 2003 and May 2006. The outcome of the technique and the technique-related complications were evaluated.
  
  
  RESULTS
  Application of the clips was possible in all patients. In 4 patients (23.5%), the endoclipping was performed via the more flexible gastroscope. En bloc resection of colon polyps was achieved in all patients. No immediate or late bleeding or perforation occurred. One patient (5.9%) developed postcoagulation syndrome and was successfully treated conservatively. Histologic examination showed in situ carcinoma in 6 polyps (33.3%). Follow-up colonoscopy demonstrated no recurrence of polyps or cancer development.
  
  
  CONCLUSIONS
  Endoclipping, followed by snare transection, may be safer than conventional polypectomy in large pedunculated colorectal polyps. Special attention is needed not to cut very close to clips to avoid thermal injury of colonic wall.
authors.affiliation: Department of Endoscopy, Central Hospital, Thessaloniki, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Katsinelos
authors.forename: Grigoris
authors.initials: G
authors.lastname: Chatzimavroudis
authors.forename: Basilis
authors.initials: B
authors.lastname: Papaziogas
authors.forename: Christos
authors.initials: C
authors.lastname: Zavos
authors.forename: George
authors.initials: G
authors.lastname: Paroutoglou
authors.forename: Ioannis
authors.initials: I
authors.lastname: Pilpilidis
authors.forename: Themistoklis
authors.initials: T
authors.lastname: Vasiliadis
authors.forename: Jannis
authors.initials: J
authors.lastname: Kountouras
mesh_terms: D000328:Adult; D000368:Aged; D003111:Colonic Polyps / Q000473:pathology / Q000601:surgery*; D003113:Colonoscopy / Q000379:methods; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies