Microarray comparative genomic hybridization for the analysis of bacterial population genetics and evolution.
Comparative genomic hybridization analyses have contributed greatly to our understanding of bacterial evolution, population genetics, and pathogenesis. Here, we describe a robust protocol for microarray-based comparison of genome content, which could be applied to any bacterial species of interest.
Guinane
Caitriona M
CM
Centre for Infectious Diseases, Chancellor's Building, New Royal Infirmary, University of Edinburgh, Edinburgh, Scotland, UK.
Fitzgerald
J Ross
JR
D001419:Bacteria / Q000145:classification / Q000235:genetics* / Q000254:growth & development; D019143:Evolution, Molecular; D005828:Genetics, Population / Q000379:methods; D016680:Genome, Bacterial; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*