title: Hot water-promoted ring-opening of epoxides and aziridines by water and other nucleopliles.
abstract: Effective hydrolysis of epoxides and aziridines was conducted by heating them in water at 60 or 100 degrees C. Other types of nucleophile such as amines, sodium azide, and thiophenol could also efficiently open epoxides and aziridines in hot water. It was proposed that hot water acted as a modest acid catalyst, reactant, and solvent in the hydrolysis reactions.
authors.affiliation: The State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.forename: Yong-Tao
authors.initials: YT
authors.lastname: Cui
authors.forename: Zhao-Bing
authors.initials: ZB
authors.lastname: Xu
authors.forename: Jin
authors.initials: J
authors.lastname: Qu