[Clinical research on the treatment of patients with cervical carcinoma using three-dimensional conformal radiotherapy].
OBJECTIVE
To explore the clinical treatment effect of three-dimensional conformal radiotherapy (3DCRT) in cervical carcinoma in comparison with traditional radiotherapy.


METHODS
Totally 50 cases of cervical carcinoma were treated with 3DCRT, and another 30 cases treated with routine radiotherapy were selected during the same period as the control group. The short-term treatment effect and acute reaction in both groups were observed.


RESULTS
The short-term effective rates of the treatment group and the control group were respectively 96% (27/28) and 97% (29/30), with no significant difference (P > 0.05). The effective rates of patients with recurrence or metastasis were respectively 92% (12/13) and 7/9. The rate of acute radiation reaction of the rectum between the treatment group and control group were respectively 46% (13/28) and 80% (24/30), with a significant difference (P < 0.05). The rate of bone marrow depression of the two groups were respectively 71% (20/28) and 63% (19/30), with no significant difference (P > 0.05), while the rate of severe bone marrow depression between two groups showed a significant difference (0 and 13%, P < 0.05). The rates of acute radiation reaction of the bladder between two groups were respectively 7% (2/28) and 3% (1/30), with no significant difference (P > 0.05).


CONCLUSIONS
The therapeutic effect of 3DCRT is similar to that of traditional radiotherapy in the treatment of cervical carcinoma, but the former treatment method has a lower rate of acute complications.
Che
Shao-min
SM
Department of Radiotherapy, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China. chersm@126.com
Liu
Zi
Z
Chen
Hong-wei
HW
Zheng
Wei
W
Su
Jin
J
Gao
Ying
Y
Yang
Yun-yi
YY
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology / Q000528:radiation effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy*