6th international symposium on retroviral nucleocapsid.
Retroviruses and LTR-retrotransposons are widespread in all living organisms and, in some instances such as for HIV, can be a serious threat to the human health. The retroviral nucleocapsid is the inner structure of the virus where several hundred nucleocapsid protein (NC) molecules coat the dimeric, genomic RNA. During the past twenty years, NC was found to play multiple roles in the viral life cycle (Fig. 1), notably during the copying of the genomic RNA into the proviral DNA by viral reverse transcriptase and integrase, and is therefore considered to be a prime target for anti-HIV therapy. The 6th NC symposium was held in the beautiful city of Amsterdam, the Netherlands, on the 20th and 21st of September 2007. All aspects of NC biology, from structure to function and to anti-HIV vaccination, were covered during this meeting.
Berkhout
Ben
B
LaboRetro INSERM #758, Ecole Normale Supérieure de Lyon, IFR 128 Biosciences Lyon-Gerland, 69364 Lyon Cedex 07, France. b.berkhout@amc.uva.nl
Gorelick
Robert
R
Summers
Michael F
MF
Mély
Yves
Y
Darlix
Jean-Luc
JL
D006801:Humans; D008958:Models, Molecular; D019251:Nucleocapsid / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D019590:Nucleocapsid Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D012190:Retroviridae / Q000235:genetics / Q000502:physiology*; D012192:Retroviridae Infections
D019590:Nucleocapsid Proteins