Diagnosis and management of lipomatous tumors.
Lipomatous tumors range from benign lipomas to high-grade liposarcomas. Liposarcomas are classified into five histologic subtypes: well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic, which differ in outcomes and patterns of recurrence. Surgical resection is the mainstay of curative treatment; however, large, high grade liposarcomas may benefit from multimodality treatment with chemotherapy and radiation. A histologic-subtype specific nomogram provides accurate survival predictions. Prospective randomized clinical trials will continue to improve our care of patients with liposarcoma.
Dalal
Kimberly Moore
KM
Department of Surgery, David Grant United States Air Force Medical Center, Travis Air Force Base, California 94535, USA. kimberlydalal@yahoo.com
Antonescu
Cristina R
CR
Singer
Samuel
S
D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D008067:Lipoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D011379:Prognosis