title: Phytochemical and biological investigation of Hymenocallis littoralis SALISB.
abstract: A phytochemical investigation of the bulbs and flowers of Hymenocallis littoralis SALISB., cultivated in Egypt, was carried out, which resulted in the isolation of four alkaloids, lycorine (1), hippeastrine (2), 11-hydroxyvittatine (3), and (+)-8-O-demethylmaritidine (4), and of two flavonoids, quercetin 3'-O-glucoside (5), and rutin (6). The volatile constituents of the plant flowers were analyzed for the first time by GC/MS, which led to the identification of 26 known compounds (Table 1). Finally, the antimicrobial activity of the petroleum ether extract of the flowers of H. littoralis was investigated.
authors.affiliation: Faculty of Pharmacy, Pharmacognosy Department, University of Alexandria, Alexandria 21521, Egypt.
authors.forename: Amina H
authors.initials: AH
authors.lastname: Abou-Donia
authors.forename: Soad M
authors.initials: SM
authors.lastname: Toaima
authors.forename: Hala M
authors.initials: HM
authors.lastname: Hammoda
authors.forename: Eman
authors.initials: E
authors.lastname: Shawky
authors.forename: Eri
authors.initials: E
authors.lastname: Kinoshita
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takayama
mesh_terms: D047151:Amaryllidaceae Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D035264:Flowers / Q000737:chemistry; D005960:Glucosides; D019684:Magnoliopsida / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010617:Phenanthridines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011794:Quercetin / Q000031:analogs & derivatives; D012431:Rutin / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: C532084:11-hydroxyvittatine; C459635:8-demethylmaritidine; D047151:Amaryllidaceae Alkaloids; D000900:Anti-Bacterial Agents; D005419:Flavonoids; D005960:Glucosides; D010617:Phenanthridines; C532085:quercetin 3'-O-glucoside; C060577:hippeastrine; D012431:Rutin; D011794:Quercetin; C015330:lycorine