title: Quantitative analysis on tongue inspection in traditional Chinese medicine using optical coherence tomography.
abstract: Tongue inspection (TI) is an important and unique diagnostic method in traditional Chinese medicine (TCM), because significant connections between various viscerae diseases and abnormalities in the tongue have been verified. In TCM, TI is simple and non invasive, but in clinical applications, TI is subjectively based on the experience and technique of physicians. To avoid this problem, optical coherence tomography (OCT) imaging is introduced here for TI. We study OCT imaging in rats in vivo from chronic gastritis group (model) and normal group (control) and quantitatively analyze the relative parameters, such as the thickness and the moisture degree of TI. Our results show that OCT images properly demonstrate the thickness of the tongue coating and the moisture degree of the tongue in both groups, and the thickness is increased in the model group from that in the normal group, while the moisture degree decreases. As a result, OCT technology has the potential to provide physicians with an objective diagnostic standard for visual TI in TCM clinical practice and research.
authors.affiliation: South China Normal University, Ministry of Education Key Laboratory of Laser Life Science, Laboratory of Photonic Traditional Chinese Medicine, Guangzhou 510631, China.
authors.forename: Haixin
authors.initials: H
authors.lastname: Dong
authors.forename: Zhouyi
authors.initials: Z
authors.lastname: Guo
authors.forename: Changchun
authors.initials: C
authors.lastname: Zeng
authors.forename: Huiqing
authors.initials: H
authors.lastname: Zhong
authors.forename: Yonghong
authors.initials: Y
authors.lastname: He
authors.forename: Ruikang K
authors.initials: RK
authors.lastname: Wang
authors.forename: Songhao
authors.initials: S
authors.lastname: Liu
mesh_terms: D000818:Animals; D005260:Female; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008516:Medicine, Chinese Traditional / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D041623:Tomography, Optical Coherence / Q000379:methods*; D014059:Tongue / Q000473:pathology*; D014060:Tongue Diseases / Q000473:pathology*