Predicting fluorouracil toxicity: can we finally do it?
Ezzeldin
Hany H
HH
Diasio
Robert B
RB
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D003967:Diarrhea / Q000139:chemically induced / Q000209:etiology* / Q000235:genetics; D042943:Dihydrouracil Dehydrogenase (NADP) / Q000235:genetics; D005472:Fluorouracil / Q000009:adverse effects*; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects; D007970:Leukopenia / Q000139:chemically induced / Q000209:etiology* / Q000235:genetics; D016015:Logistic Models; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics; D052016:Mucositis / Q000139:chemically induced / Q000209:etiology* / Q000235:genetics; D016017:Odds Ratio; D018579:Patient Selection; D011110:Polymorphism, Genetic; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D013940:Thymidylate Synthase / Q000235:genetics; D014803:Vitamin B Complex / Q000009:adverse effects
D000964:Antimetabolites, Antineoplastic; D014803:Vitamin B Complex; D042943:Dihydrouracil Dehydrogenase (NADP); D042965:Methylenetetrahydrofolate Reductase (NADPH2); D013940:Thymidylate Synthase; D002955:Leucovorin; D005472:Fluorouracil