title: Reflux oesophagitis in Italy (Diomede project).
abstract: OBJECTIVE
  A multicentric observational study was performed to update the available information on reflux oesophagitis in Italy.
  
  
  METHODS
  In phase I, the number and severity of reflux oesophagitis diagnosed in 1 year (2003) were reported together with the associated endoscopic findings. In phase II, oesophagitis patients consecutively referred in a 3-month period were analysed. A multivariate analysis was used to identify the risk factors for severe oesophagitis.
  
  
  RESULTS
  253,992 upper endoscopies were collected. The overall prevalence of oesophagitis was 14.8% and the endoscopic findings associated with oesophagitis were hiatus hernia (46.3%), duodenal ulcer (10.7%), gastric ulcer (3.6%) and Barrett's oesophagus (2.9%). In phase II, 1542 reflux oesophagitis patients were analysed (60.3% males; mean age 50.7 +/-16.6 years). Only 53.4% of patients reported heartburn and/or regurgitation as main complaint. Severe symptoms, age > 50 years, hiatus hernia and male gender were identified as independent predictors of severe oesophagitis.
  
  
  CONCLUSIONS
  Oesophagitis is the most frequent among the peptic diseases of the upper gastro-intestinal tract. Only half of the oesophagitis patients reported typical reflux symptoms as dominant. Advanced age, male gender, severe symptoms and hiatus hernia were independent risk factors for severe disease.
authors.affiliation: Gastroenterology, S. Orsola-Malpighi Hospital, Bologna, Italy. baldi@med.unibo.it
authors.forename: F
authors.initials: F
authors.lastname: Baldi
authors.forename: C
authors.initials: C
authors.lastname: Cavoli
authors.forename: R
authors.initials: R
authors.lastname: Solimando
authors.forename: M A
authors.initials: MA
authors.lastname: Bianco
authors.forename: L
authors.initials: L
authors.lastname: Cipolletta
authors.forename: G
authors.initials: G
authors.lastname: Costamagna
authors.forename: S
authors.initials: S
authors.lastname: Passaretti
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D004942:Esophagitis, Peptic / Q000175:diagnosis* / Q000453:epidemiology*; D004945:Esophagoscopy; D005260:Female; D006551:Hernia, Hiatal / Q000150:complications*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors