Desquamative gingivitis: retrospective analysis of disease associations of a large cohort.
BACKGROUND
Desquamative gingivitis (DG) is usually a manifestation of immunologically mediated mucocutaneous disorders, although it was previously suggested to be hormonally related.


METHODS
One hundred and eighty-seven Caucasian UK residents with clinical features of DG (126 female, median age of 51 years, range 23-93 years) were retrospectively evaluated.


RESULTS
It was established that, in this population, the largest cohort yet reported, oral lichen planus was most common (70.5%) while mucous membrane pemphigoid (14%), pemphigus vulgaris (13%), linear IgA disease (1.6%), dermatomyositis (0.5%) and mixed connective tissue disease (0.5%) were less common.


CONCLUSIONS
Oral lichen planus is the main disorder associated with DG. However, DG may be a feature of bullous disease and connective tissue disease.
Leao
J C
JC
Departamento de Clínica e Odontologia Preventiva, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Ingafou
M
M
Khan
A
A
Scully
C
C
Porter
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003882:Dermatomyositis / Q000150:complications; D005260:Female; D005891:Gingivitis / Q000209:etiology* / Q000276:immunology; D006561:Herpes Simplex / Q000150:complications; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D017676:Lichen Planus, Oral / Q000150:complications; D008297:Male; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000150:complications; D009059:Mouth Diseases / Q000276:immunology; D010390:Pemphigoid, Benign Mucous Membrane; D010392:Pemphigus / Q000150:complications; D012189:Retrospective Studies; D012872:Skin Diseases, Vesiculobullous / Q000276:immunology; D055815:Young Adult
D007070:Immunoglobulin A