Michael additions of amines to methyl acrylates promoted by microwave irradiation.
A simple and efficient protocol has been developed for the Michael addition of amines to alpha,beta-unsaturated esters under microwave irradiation. Under these conditions there was a significant decrease in the reaction time, increases in the yields and increased purity of the products.
Escalante
Jaime
J
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Col. Chamilpa, C.P. 62210 Cuernavaca, Mor., México. jaime@ciq.uaem.mx
Carrillo-Morales
Manuel
M
Linzaga
Irma
I
D000179:Acrylates / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D001596:Benzylamines / Q000737:chemistry; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D008872:Microwaves; D008956:Models, Chemical
D000179:Acrylates; D000588:Amines; D001596:Benzylamines; D004952:Esters; C035956:methyl acrylate