title: Clinical research trials: factors that influence and hinder participation.
abstract: The objective of this study was to examine factors that influence and hinder participation of African Americans in clinical research trials. Specifically, we examined and compared the perceived advantages and disadvantages to participation in clinical research trials, exposure to selected experiences prior to participation (i.e., who and what influenced the decision to participate or not), and perceptions regarding necessary preparation for participation in clinical research trials. Three hundred eighty six African Americans responded to the questionnaire that was administered in the study. As expected, African Americans who had previously participated in a clinical research trial agreed with factors perceived as advantages to participation, while respondents who had not previously participated endorsed factors perceived as potential disadvantages to participation in clinical research trials.
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA. kennedbm@pbrc.edu
authors.forename: Betty M
authors.initials: BM
authors.lastname: Kennedy
authors.forename: Michael F
authors.initials: MF
authors.lastname: Burnett
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D001741:Black or African American / Q000208:ethnology*; D000533:Altruism; D000704:Analysis of Variance; D002986:Clinical Trials as Topic / Q000523:psychology*; D005163:Factor Analysis, Statistical; D005239:Fear; D017144:Focus Groups; D007722:Health Knowledge, Attitudes, Practice; D006304:Health Status; D006801:Humans; D008145:Louisiana; D015404:Nursing Methodology Research; D010342:Patient Acceptance of Health Care / Q000208:ethnology*; D010344:Patient Advocacy; D010353:Patient Education as Topic; D018579:Patient Selection; D035842:Research Subjects / Q000523:psychology*; D011795:Surveys and Questionnaires; D035502:Trust; D035501:Uncertainty; D016526:Workload