title: Research on coagulation of unwashed shed blood after total knee replacement in Chinese patients.
abstract: To evaluate quality of unwashed but filtered wound shed blood through ConstaVac blood conservation system (Stryker Company) after total knee replacement, we selected 30 patients who underwent total knee replacement consecutively from July 2003 to July 2004 and received retransfusion of wound shed blood. Pre- and postoperative coagulative factors of peripheral vein blood and wound shed blood were measured, such as fibrinogen, AT-III, D-dimer, plasminogen, and PT, APTT were also measured. No clinical evidence of coagulation and DIC appeared in these patients. There is significant change of coagulative factors in unwashed but filtered wound shed blood and it may cause a potential risk of coagulopathy to retransfuse wound shed blood, but retransfusion of unwashed but filtered shed blood appeared to be relative safe clinically.
authors.affiliation: Arthritis Clinic & Research Center, Peking University People's Hospital, Beijing, China.
authors.forename: Zhen-Peng
authors.initials: ZP
authors.lastname: Guan
authors.forename: Jun
authors.initials: J
authors.lastname: Jiang
authors.forename: Hou-Shan
authors.initials: HS
authors.lastname: Lv
authors.forename: Ning
authors.initials: N
authors.lastname: Wang
mesh_terms: D019645:Arthroplasty, Replacement, Knee; D001777:Blood Coagulation / Q000502:physiology*; D016063:Blood Loss, Surgical / Q000503:physiopathology*; D001803:Blood Transfusion; D001810:Blood Volume; D002681:China; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D010314:Partial Thromboplastin Time; D010958:Plasminogen / Q000032:analysis; D011517:Prothrombin Time
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005340:Fibrinogen; D010958:Plasminogen