Survey of vaginal-flora Candida species isolates from women of different age groups by use of species-specific PCR detection.
A retrospective survey of 93,775 samples testing positive in Candida species-specific PCR tests performed on cervicovaginal swabs over a 4-year period demonstrated consistent yearly distributions of Candida albicans (89%), C. glabrata (7.9%), C. parapsilosis (1.7%), and C. tropicalis (1.4%). However, the species distributions among different age groups revealed increases in the percentages of non-albicans species with increases in age.
Vermitsky
John-Paul
JP
Antimicrobial Resistance Division, Research and Development Department, Medical Diagnostic Laboratories, L.L.C., 2439 Kuser Road, Hamilton, NJ 08690, USA. sgygax@mdlab.com
Self
Matthew J
MJ
Chadwick
Sean G
SG
Trama
Jason P
JP
Adelson
Martin E
ME
Mordechai
Eli
E
Gygax
Scott E
SE
D000328:Adult; D000367:Age Factors; D000368:Aged; D002175:Candida / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D002176:Candida albicans / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000453:epidemiology* / Q000382:microbiology*; D002584:Cervix Uteri / Q000382:microbiology; D004271:DNA, Fungal; D005260:Female; D006801:Humans; D008875:Middle Aged; D016533:Mycological Typing Techniques; D016133:Polymerase Chain Reaction / Q000379:methods; D013045:Species Specificity; D014481:United States / Q000453:epidemiology; D014621:Vagina / Q000382:microbiology*
D004271:DNA, Fungal