title: Angiomyofibroblastoma of the vulva.
abstract: Angiomyofibroblastoma is a benign well-circumscribed tumor characterized by alternating hypocellular and hypercellular areas with abundant thin-walled blood vessels. The tumor cells are bland and spindle-shaped or epitheloid and tend to concentrate around the vessels or cluster in small nests. Herein, we report a case of angiomyofibroblastoma of the left labia major in a 50-year-old female. The tumor measured 18 x 16 x 11 cm and appeared as an ulcerated rubbery vulvar mass with rapid enlargement during one month. Ultrasonography demonstrated a soft tissue tumor with homogeneous echo and normal vascularity. Histologically, cells were positive for vimentine, desmin, and estrogen and progesterone receptors but negative for cytokeratin; all in favor of the diagnosis of angiomyofibroblastoma.
authors.affiliation: Department of Gynecology, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Shahnaz
authors.initials: S
authors.lastname: Barat
authors.forename: Soudabeh
authors.initials: S
authors.lastname: Tirgar-Tabari
authors.forename: Shahryar
authors.initials: S
authors.lastname: Shafaee
mesh_terms: D018322:Angiofibroma / Q000175:diagnosis* / Q000601:surgery; D018229:Angiomyoma / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000601:surgery