title: Multiple pathways to osteoarthritis and articular fractures: is subchondral bone the culprit?
abstract: Osteoarthritis and articular fractures are commonly responsible for early retirement from athletic performance. The subchondral bone (SCB) in those conditions is being recognized as an integral component in their pathophysiology. Early recognition of these potentially career-ending diseases may require understanding of the progression of changes occurring in SCB with time and exercise.
authors.affiliation: Department of Clinical Studies, Comparative Orthopaedics Research Laboratory, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. acruz@uoguelph.ca
authors.forename: Antonio M
authors.initials: AM
authors.lastname: Cruz
authors.forename: Mark B
authors.initials: MB
authors.lastname: Hurtig
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D016723:Bone Remodeling; D001842:Bone and Bones / Q000293:injuries* / Q000473:pathology*; D002358:Cartilage, Articular / Q000293:injuries / Q000473:pathology; D006734:Horse Diseases / Q000209:etiology / Q000473:pathology*; D006736:Horses / Q000293:injuries*; D007794:Lameness, Animal; D010003:Osteoarthritis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D013643:Tarsus, Animal / Q000293:injuries / Q000473:pathology