title: Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells.
abstract: The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a significant decrease in most of the intestinal endocrine cells (p < 0.01) compared with the control group. The significant quantitative changes in the intestinal endocrine cell density might contribute to the development of the gastrointestinal symptoms commonly encountered in cancer patients.
authors.affiliation: Department of Radiological Science, College of Health Science, Catholic University of Daegu, Daegu 712-702, Korea.
authors.forename: Kwang-Ho
authors.initials: KH
authors.lastname: Cho
authors.forename: Hyeung-Sik
authors.initials: HS
authors.lastname: Lee
authors.forename: Sae-Kwang
authors.initials: SK
authors.lastname: Ku
mesh_terms: D000818:Animals; D019858:Enteroendocrine Cells / Q000378:metabolism / Q000473:pathology*; D005260:Female; D041981:Gastrointestinal Tract / Q000473:pathology; D005934:Glucagon / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000378:metabolism / Q000473:pathology*; D010191:Pancreatic Polypeptide / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D012844:Sincalide / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism
chemical_list: D012701:Serotonin; D013004:Somatostatin; D010191:Pancreatic Polypeptide; D005934:Glucagon; D012844:Sincalide