title: Gastric cancer staging at isotropic MDCT including coronal and sagittal MPR images: endoscopically diagnosed early vs. advanced gastric cancer.
abstract: BACKGROUND
  The aims of this study are to evaluate and compare the accuracies of isotropic multi-detector row CT (MDCT) including multiplanar reconstruction (MPR) images for preoperative staging of endoscopically diagnosed early gastric cancer (eEGC) and advanced gastric cancer (eAGC).
  
  
  METHODS
  One hundred and five patients with endoscopically proven gastric cancer underwent isotropic MDCT. Three independent radiologists evaluated T and N staging both on transverse images only and on three orthogonal MPR images. The staging of each tumor was surgico-pathologically confirmed. The receiver operating characteristic (ROC) analysis and the Wilcoxon signed ranked test were used for statistical analyses.
  
  
  RESULTS
  In 30 eAGCs, the accuracies for T and N staging with MPR imaging were better than those with transverse imaging (each P < 0.05). In 34 eEGCs, however, only the accuracy of T2 or higher with MPR imaging was higher than that with transverse imaging (P < 0.05).
  
  
  CONCLUSIONS
  Isotropic MDCT with MPR images including coronal or sagittal reconstructions can improve the accuracies of preoperative T and N staging of eAGC, while having little impact on the accuracy for eEGC.
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-Ku, Seoul, Republic of Korea.
authors.forename: Yoo Na
authors.initials: YN
authors.lastname: Kim
authors.forename: Dongil
authors.initials: D
authors.lastname: Choi
authors.forename: Seong Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Min Ju
authors.initials: MJ
authors.lastname: Kim
authors.forename: Soon Jin
authors.initials: SJ
authors.lastname: Lee
authors.forename: Won Jae
authors.initials: WJ
authors.lastname: Lee
authors.forename: Sung
authors.initials: S
authors.lastname: Kim
authors.forename: Jae J
authors.initials: JJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D005773:Gastroscopy; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012372:ROC Curve; D018709:Statistics, Nonparametric; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide