title: [Surface-enhanced Raman spectra of natural tissue and cancerous tissue of lung].
abstract: Surface-enhanced Raman spectra of natural tissue and cancerous tissue of lung from 300 to 1700 cm(-1) were measured. In the cancerous tissue of lung, the orderly conformations of amides III and amides I of the main chains in protein such as alpha-helix, beta-corner and no rules curly were damaged seriously; conversely, the extendable vibration of skeleton C-N and skeleton C-C increased. Side chains change became complicated. In general, the content of nucleic acids increases in the cancer tissue of lung. The lengthways conformations of lecithoid chains is out-of-order in the cancerous tissue of lung compared with the natural ones.
authors.affiliation: Photonics Center of School of Physics, Nankai University, Tianjin 300071, China. nklyn@mail.nankai.edu.cn
authors.forename: Yan-nan
authors.initials: YN
authors.lastname: Liu
authors.forename: Zu-quan
authors.initials: ZQ
authors.lastname: Zou
authors.forename: Yan-qing
authors.initials: YQ
authors.lastname: Liu
authors.forename: Xiao-xuan
authors.initials: XX
authors.lastname: Xu
authors.forename: Gang
authors.initials: G
authors.lastname: Yu
authors.forename: Cun-zhou
authors.initials: CZ
authors.lastname: Zhang
mesh_terms: D000588:Amines / Q000032:analysis; D006801:Humans; D008168:Lung / Q000737:chemistry* / Q000473:pathology; D008175:Lung Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D000588:Amines; D011506:Proteins