Human cathepsin D.
A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.
Minarowska
Alina
A
3rd Department of Children's Diseases, Medical University, Bialystok, Poland. lukmin@mp.pl
Gacko
Marek
M
Karwowska
Alicja
A
Minarowski
Łukasz
Ł
D000595:Amino Acid Sequence; D002402:Cathepsin D / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D011499:Protein Processing, Post-Translational; D013379:Substrate Specificity
D002402:Cathepsin D