Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia: a case report and review of literature.
Well differentiated villoglandular adenocarcinoma of uterine cervix is a rare tumour which usually occurs in young women. It is considered to be an indolent tumour with favorable prognosis and most of them were treated by conservative procedures. We report a 35 year old lady who came with complaints of 3 months amenorrhoea and an episode of spontaneous bleeding. Urine pregnancy test was negative. Physical examination revealed a cervical polyp. Histopathological findings were consistent with villoglandular papillary adenocarcinoma associated with high grade cervical intraepithelial neoplasia (CIN-3). Left parametrial and left ureteral involvement, proved by biopsy, causing left hydroureteronephrosis was detected. The patient was thus found to be in an advanced stage, stage- III b (FIGO). The patient is currently undergoing radiotherapy. A review of literature showed that only occasional cases showing disease spread have been reported, suggesting caution in the management and regular follow up of the patient.
Srilatha
P S
PS
Department of Pathology, Melaka Manipal Medical College Manipal, Karnataka. drsrilatha2003@hotmail.com
Roy
Alfred
A
D000231:Adenocarcinoma, Papillary / Q000150:complications* / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy; D000290:Adnexa Uteri / Q000473:pathology; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006869:Hydronephrosis; D011127:Polyps; D014513:Ureter / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy; D002578:Uterine Cervical Dysplasia / Q000150:complications* / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy
D000970:Antineoplastic Agents; D002945:Cisplatin