title: Surgical resection of primary liposarcoma of the anterior mediastinum.
abstract: We report on the rare and surgical treatment of a case of primary mediastinal liposarcoma. A 64-year-old male complained of hoarseness for one month and was admitted to our hospital because of an abnormal shadow, which was postulated to be an anterior mediastinal tumor on a chest computed tomography (CT) scan. Horizontal T1-weighted magnetic resonance imaging (MRI) showed an anterior mediastinal round mass with a signal intensity similar to that of subcutaneous fat, which was 6.5 cm in diameter. An operation similar to extended thymectomy was perfomed through a median sternotomy. Histological examination of the resected specimen revealed that the tumor was composed of well-differentiated liposarcoma and pleomorphic malignant fibrous histiocytoma and the tumor was diagnosed as a de-differentiated liposarcoma. We discuss it with reference to a collective review of the Japanese literature for surgical cases of primary liposarcoma of the mediastinum.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Hirai
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Hamanaka
authors.forename: Norimasa
authors.initials: N
authors.lastname: Mitsui
authors.forename: Shinnosuke
authors.initials: S
authors.lastname: Uegami
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Matsuura
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed