title: Segmental early relaxation phenomenon as determined by tissue Doppler imaging.
abstract: BACKGROUND
  The early diastolic peak velocity of left ventricular (LV) wall segment has always been thought to appear in the rapid filling phase. However, we find a segmental early relaxation phenomenon (SERP), characterized by an early diastolic peak velocity lying in the isovolumic relaxation (IVR) period. The present study aimed to investigate the characteristics of SERP segments with tissue Doppler imaging (TDI) echocardiography.
  
  
  METHODS
  TDI was performed in 119 patients with known or suspected coronary heart disease (CHD) and 60 normal subjects. The segmental early diastolic velocity pattern was classified as normal pattern (NP), postsystolic shortening (PSS) and SERP.
  
  
  RESULTS
  Segmental early diastolic velocity pattern was significantly associated with actual coronary diameter stenosis, relative coronary stenosis, wall motion score, and segmental location in LV wall. Compared with other segments, SERP segments had a higher IVR velocity and lower early diastolic peak velocity.
  
  
  CONCLUSIONS
  SERP most frequently occurs in the distribution of artery with the relatively mildest stenosis, and is more likely accompanied by simultaneous PSS elsewhere in LV wall, which occurs most frequently in the distribution of artery with the relatively most severe stenosis. A decreased early diastolic peak velocity of SERP segment dose not necessarily mean impaired myocardial relaxation.
authors.affiliation: Department of Physiology, Xijing Hospital, Fourth Military Medical Unviersity, Xi'an, China. fmmuzhanghaibin@hotmail.com
authors.forename: Haibin
authors.initials: H
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Song
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Zhu
authors.forename: Hongling
authors.initials: H
authors.lastname: Li
authors.forename: Ting
authors.initials: T
authors.lastname: Zhu
authors.forename: Yunqiu
authors.initials: Y
authors.lastname: Qian
authors.forename: Liwen
authors.initials: L
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zhou
authors.forename: Miaozhang
authors.initials: M
authors.lastname: Zhu
mesh_terms: D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003971:Diastole; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D015203:Reproducibility of Results; D016277:Ventricular Function, Left