Facile synthesis of high-density poly(octadecyl acrylate)-grafted silica for reversed-phase high-performance liquid chromatography by surface-initiated atom transfer radical polymerization.
To introduce high-density polymeric organic phase onto silica, initiator-modified silica was prepared and then surface-initiated atom transfer radical polymerization (ATRP) ("grafting-from" method) was carried out with octadecyl acrylate. The resultant polymer-grafted silica was characterized by diffuse reflectance infrared Fourier transform, suspension-state (1)H NMR, solid-state (13)C cross-polarization magic angle spinning nuclear magnetic resonance (CP-MAS-NMR), solid-state (29)Si-CP-MAS-NMR spectroscopies, elemental analysis and differential scanning calorimetry measurements. ATRP-based poly(octadecyl acrylate)-grafted silica (Sil-ODA(n)-1), was used as a stationary phase in high-performance liquid chromatography (HPLC) and the chromatographic behavior was evaluated by the retention studies of polycyclic aromatic hydrocarbons (PAHs) and aromatic positional isomers. Compared with previous poly(octadecyl acrylate)-grafted silica (Sil-ODA(n)), which was prepared by the "grafting-to" method, we have observed longer retention and greater selectivity for Sil-ODA(n)-1 towards PAHs event at higher temperature.
Mallik
Abul K
AK
Department of Applied Chemistry and Biochemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan.
Rahman
M Mizanur
MM
Czaun
Miklos
M
Takafuji
Makoto
M
Ihara
Hirotaka
H
D000179:Acrylates / Q000138:chemical synthesis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D011084:Polycyclic Aromatic Hydrocarbons / Q000302:isolation & purification; D012822:Silicon Dioxide / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature
D000179:Acrylates; D011084:Polycyclic Aromatic Hydrocarbons; C513222:poly(octadecylacrylate); D012822:Silicon Dioxide