title: From homicide to happiness--a commentary on omega-3 fatty acids in human society. Cleave Award Lecture.
abstract: The field of omega-3 fatty acid deficiencies as reversible risk factors in major psychiatric disorders has flourished in the last decade. Treatment recommendations of the American Psychiatric Association may be considered for application to more normative states of psychiatric health. Considered here is the proposition that an increased risk of personality disorders, and an increased sense of despair in normative populations, might be considered as symptoms of deficiencies of omega-3 fatty acids. The major changes in the essential fatty acid composition of the food supply, including increased availability of the omega-6 linoleic acid, may be correlated not only with increased risks of homicide, but also increased risks of suicide and suboptimal social cohesion.
authors.affiliation: Section on Nutritional Neurosciences, Laboratory of Membrane Biochenmistr and Biophysics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892-2088, USA. jhibbeln@mail.nih.gov
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Hibbeln
mesh_terms: D001363:Awards and Prizes; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D003863:Depression / Q000453:epidemiology / Q000209:etiology; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage* / Q000502:physiology; D006708:Homicide / Q000523:psychology / Q000706:statistics & numerical data; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D009751:Nutritional Requirements; D009752:Nutritional Status; D013405:Suicide / Q000523:psychology / Q000706:statistics & numerical data
chemical_list: D015525:Fatty Acids, Omega-3