title: Formal total synthesis of triptolide.
abstract: A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels-Alder reactions and a new deoxygenative aromatisation process.
authors.affiliation: Research School of Chemistry, Australian National University, Canberra, ACT 0200, Australia.
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Miller
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Willis
authors.forename: Michael S
authors.initials: MS
authors.lastname: Sherburn
mesh_terms: D004224:Diterpenes / Q000138:chemical synthesis*; D004852:Epoxy Compounds / Q000138:chemical synthesis; D010616:Phenanthrenes / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; D004852:Epoxy Compounds; D010616:Phenanthrenes; C001899:triptolide