Correlation of autism with temporal tubers in tuberous sclerosis complex.
Tuberous sclerosis complex (TSC) is an inherited genetic disorder commonly associated with neuropsychiatric complications like epilepsy, mental retardation, autism and other behavioral problems and constitutes about 1-4% of the autistic population. Mental retardation and seizures, particularly infantile spasms are significant risk factors for the development of autism. Patients of TSC with autism are more likely to have temporal tubers than those cases without autism. We describe clinical and neuroimaging features of two such cases of tuberous sclerosis with autism.
Kothur
Kavitha
K
Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ray
Munni
M
Malhi
Prahbhjot
P
D001321:Autistic Disorder / Q000150:complications* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D013702:Temporal Lobe / Q000473:pathology*; D014402:Tuberous Sclerosis / Q000150:complications* / Q000473:pathology*