[Unusual venous thrombosis revealing a human immunodeficiency virus infection and a protein S deficiency. Two cases and literature review].
The authors report two cases of unusual venous thrombosis associated with protein S deficiency in patients with the acquired immunodeficiency syndrome. The first case was a superior mesenteric vein thrombosis caused by HIV-1 infection associated with protein S deficiency in a 53-year-old patient. The second case was a cerebral venous thrombosis in a 34-year-old patient with HIV-1 and HIV-2 infections associated with protein S deficiency. None of the two patients were receiving antiretroviral therapy at the time of diagnosis. The evolution of thrombosis was favorable in both patients with heparin therapy and antivitamin K (AVK).
Konin
C
C
Service des soins intensifs, institut de cardiologie, B.P. V 206, Abidjan 01, Côte d'Ivoire. koninchristophe@yahoo.fr
Adoh
M
M
Adoubi
A
A
Anzouan-Kacou
J B
JB
Azagoh
R
R
N'guetta
R
R
Kramoh
E
E
Séka
R
R
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D015497:HIV-1 / Q000302:isolation & purification; D015498:HIV-2 / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008642:Mesenteric Veins / Q000000981:diagnostic imaging; D008875:Middle Aged; D018455:Protein S Deficiency / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D054063:Superior Sagittal Sinus / Q000000981:diagnostic imaging; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*
D000925:Anticoagulants