title: An efficient enantioselective method for asymmetric Michael addition of nitroalkanes to alpha,beta-unsaturated aldehydes.
abstract: The addition of nitroalkanes to alpha,beta-unsaturated aldehydes under the catalysis of (S)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine and lithium acetate as additive afforded gamma-nitroaldehydes in good yield and up to 97% ee.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Science, 457 Zhongshan Road, Dalian 116023, China.
authors.forename: Yongcan
authors.initials: Y
authors.lastname: Wang
authors.forename: Pengfei
authors.initials: P
authors.lastname: Li
authors.forename: Xinmiao
authors.initials: X
authors.lastname: Liang
authors.forename: Tony Y
authors.initials: TY
authors.lastname: Zhang
authors.forename: Jinxing
authors.initials: J
authors.lastname: Ye
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000473:Alkanes / Q000737:chemistry*; D017672:Nitrogen Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000473:Alkanes; D017672:Nitrogen Compounds