title: Meta-analysis of tacrolimus ointment for atopic dermatitis in pediatric patients.
abstract: We evaluated the efficacy and safety of tacrolimus ointment in the treatment of the pediatric patients with atopic dermatitis. Tacrolimus ointment therapy resulted in the remission of atopic dermatitis, this effect of tacrolimus ointment strengths 0.03% and 0.1% were better than those of 1% hydrocortisone acetate and 1% pimecrolimus. Difference between the 0.03% tacrolimus group and the 0.1% tacrolimus group was not statistically significant.
authors.affiliation: School of Pharmacy, Shandong University, and Jinan City Hospital for Skin Diseases Prevention and Treatment, Jinan, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Yan
authors.forename: Sheng-Li
authors.initials: SL
authors.lastname: Chen
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Wang
authors.forename: Wen
authors.initials: W
authors.lastname: Zhou
authors.forename: Feng-shan
authors.initials: FS
authors.lastname: Wang
mesh_terms: D000287:Administration, Topical; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000188:drug therapy*; D019317:Evidence-Based Medicine; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009824:Ointments / Q000627:therapeutic use; D010372:Pediatrics / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D016559:Tacrolimus / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D009824:Ointments; D016559:Tacrolimus