title: [Optimal extraction of Dingxiang jiangqi granules].
abstract: OBJECTIVE
  To screen and optimize the extraction of Dingxiangjiangqi granules.
  
  
  METHODS
  The extraction route was screened by using pharmacodynamic experiment and the extraction conditions were optimized by orthogonal design and taking extract yield, content of naringin and tetrahydropalmatine as indexes.
  
  
  RESULTS
  The pharmacodynamic result showed that aqueous extract had the best effect to cure the esophagitis of rats and the optimized extraction technique was adding 12 times water, extracting 0. 5 hour for 3 times.
  
  
  CONCLUSIONS
  The optimum extraction was simple, reasonable, stable and useful for further development.
authors.affiliation: Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 200032, China.
authors.forename: Li-Hong
authors.initials: LH
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Fu
authors.forename: Zhi-Rong
authors.initials: ZR
authors.lastname: Zhang
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Wang
authors.forename: Shu-Ying
authors.initials: SY
authors.lastname: Ma
authors.forename: Sheng-Liang
authors.initials: SL
authors.lastname: Zhu
mesh_terms: D000818:Animals; D001600:Berberine Alkaloids / Q000032:analysis; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004942:Esophagitis, Peptic / Q000188:drug therapy / Q000473:pathology; D004947:Esophagus / Q000187:drug effects / Q000473:pathology; D044950:Flavanones / Q000032:analysis; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D027842:Syzygium / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D001600:Berberine Alkaloids; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D044950:Flavanones; C014215:tetrahydropalmatine; C005274:naringin