Epithelial organization: may the force be with you.
Multicellular organization is determined by the balance of forces between cells as much as by the expression of genes. A recent study in Drosophila combines physical modeling with experimental measurements and mechanical perturbations to shed light on the processes that influence cell patterns in vivo.
Fernandez-Gonzalez
Rodrigo
R
Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.
Zallen
Jennifer A
JA
D000818:Animals; D001696:Biomechanical Phenomena; D019521:Body Patterning / Q000502:physiology*; D004330:Drosophila / Q000254:growth & development*; D004848:Epithelium / Q000254:growth & development*; D008954:Models, Biological; D014921:Wings, Animal / Q000254:growth & development