F-18 FDG PET/CT demonstration of thymoma followed by development of lung cancer.
It is well-known that thymoma can be associated with diverse extrathymic malignancies. The authors present a case of a 72-year-old man with myasthenia gravis in which F-18 FDG PET/CT demonstrated high FDG uptake in both an anterior mediastinal mass and a lung nodule. The FDG uptake in the lung nodule was significantly higher than that of the thymic lesion, which might suggest the possibility of a second development of lung cancer in this thymoma patient. Surgical resection was done for the 2 tumors, and histologic examination revealed anterior mediastinal thymoma and primary adenocarcinoma of the lung. This case demonstrates the potential usefulness of PET/CT in detecting and assessing the second extrathymic malignancy in a patient with thymoma.
Choi
Jae Jeong
JJ
Department of Radiology and Nuclear Medicine, St. Vincent's Hospital, The Catholic University of Korea, 93 Ji-dong, Paidal-gu, Suwon, Korea.
Ahn
Myeong Im
MI
Park
Michael Yong
MY
Jeon
Jae Soo
JS
Park
Young Ha
YH
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary; D000368:Aged; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D049268:Positron-Emission Tomography; D011859:Radiography; D019275:Radiopharmaceuticals; D013945:Thymoma / Q000000981:diagnostic imaging* / Q000473:pathology; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18