title: The use of 18F-fluorodeoxyglucose positron emission tomography for the diagnosis and management of invasive mould infections.
abstract: There is limited information on the utility of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for the diagnosis and management of invasive mould infections (IMIs). We retrospectively evaluated patients with IMIs who underwent FDG-PET in our institution (n = 13; December 1999 to April 2004), and reviewed the available literature (n = 9). In 16 non-neutropenic patients with available FDG-PET imaging studies (11 from our institution), FDG-PET revealed an occult IMI site (n = 3; 2 unidentified CNS involvement) and was helpful in guiding the duration of treatment (n = 8). Prospective evaluation of the role of FDG-PET in the work-up and management of IMIs is needed.
authors.affiliation: Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
authors.forename: Georgios
authors.initials: G
authors.lastname: Chamilos
authors.forename: Homer A
authors.initials: HA
authors.lastname: Macapinlac
authors.forename: Dimitrios P
authors.initials: DP
authors.lastname: Kontoyiannis
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D049268:Positron-Emission Tomography / Q000379:methods*; D012189:Retrospective Studies
chemical_list: D019788:Fluorodeoxyglucose F18