title: Detection of new arr-4 and arr-5 gene cassettes in clinical Pseudomonas aeruginosa and Klebsiella pneumoniae strains from Brazil.
abstract: New arr alleles emerged in class 1 integrons from a clinical Pseudomonas aeruginosa strain (arr-4) and four Klebsiella pneumoniae strains (arr-5) in Brazil/American continent. arr-4 was preceded by aacA7-catB3, whereas arr-5 was the unique cassette. The putative proteins shared 75% (Arr-5) and 78% (Arr-4) identities with Arr-2.
authors.affiliation: Instituto Oswaldo Cruz/FIOCRUZ, Laboratório de Genética Molecular de Microrganismos, Avenida Brasil 4365, P.O. Box 926, CEP 21045-900, Manguinhos, Rio de Janeiro, Brazil. ericafon@ioc.fiocruz.br
authors.forename: Erica Lourenço
authors.initials: EL
authors.lastname: da Fonseca
authors.forename: Fernanda dos Santos
authors.initials: Fdos S
authors.lastname: Freitas
authors.forename: José Carlos
authors.initials: JC
authors.lastname: de Amorim
authors.forename: Ana Carolina Paulo
authors.initials: AC
authors.lastname: Vicente
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D001938:Brazil; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D032023:Integrons / Q000235:genetics*; D007710:Klebsiella Infections / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000235:genetics*; D008969:Molecular Sequence Data; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D004269:DNA, Bacterial