Allylation of N-heterocycles with allylic alcohols employing self-assembling palladium phosphane catalysts.
The first palladium catalyst system that allows the direct allylation of indoles with allylic alcohols as substrates with water being the only byproduct is presented. The application of self-assembling ligands based on complementary hydrogen bonding was the key to success.
Usui
Ippei
I
Institut für Organische Chemie und Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104, Freiburg, Germany.
Schmidt
Stefan
S
Keller
Manfred
M
Breit
Bernhard
B
D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006860:Hydrogen Bonding; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D020005:Propanols / Q000737:chemistry*
D006571:Heterocyclic Compounds; D010720:Phosphines; D020005:Propanols; C006463:allyl alcohol; D010165:Palladium; C044646:phosphine