Second meiotic arrest and exit in frogs and mice.
Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus, and compare and contrast them with their counterparts in mice.
Perry
Anthony C F
AC
Laboratory of Mammalian Molecular Embryology, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan. perry135@aol.com
Verlhac
Marie-Hélène
MH
D000818:Animals; D001001:Anura / Q000378:metabolism*; D020013:Calcium Signaling; D006706:Homeostasis; D008297:Male; D008540:Meiosis; D008677:Metaphase; D051379:Mice; D013094:Spermatozoa / Q000166:cytology