[Experimental navigation and deuteroexhaustive exercise suppress the function of the hypothalamic-pituitary-testicle axis in rats].
OBJECTIVE
To study the effects of experimental navigation and deuteroexhaustive exercise on the serum levels of testosterone (T), corticosterone (CORT), luteinizing hormone (LH) and follicle stimulating hormone (FSH).


METHODS
Thirty-six male SD rats were randomly divided into an experimental navigation group (Group A), which underwent 180 min wearing floating with psychological stress, a deuteroexhaustive exercise group (Group B), which were subjected to 120 min intensive running on the treadmill after the accomplishment of the same procedure as Group A, and a control group (Group C). Blood samples were obtained at the end of the experiment to determine the T, CORT, LH and FSH of the rats.


RESULTS
Compared with Group C, serum T was statistically decreased in Group A and B (P < 0.05), while CORT was increased slightly in Group A and significantly in Group B (P < 0.05). A statistically lower level of serum LH was observed in Group B (P < 0.05), but no significant differences were found in serum FSH among the three groups.


CONCLUSIONS
Stresses of experimental navigation and intensive exercise suppress the function of the hypothalamic-pituitary-testicle axis in rats.
Li
Jie
J
Department of Endocrinology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.
Wang
Jian
J
Zhao
Dan
D
Hu
Lan-Ping
LP
Shao
Jia-Qing
JQ
Gu
Ping
P
Wang
Yang-Tian
YT
D000818:Animals; D003345:Corticosterone / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013315:Stress, Psychological / Q000097:blood / Q000503:physiopathology*; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D003345:Corticosterone