The controversies regarding the role of estrogens in urogynecology.
Estrogens are crucial for the proper functioning of genitourinary tract. Hypoestrogenism related to menopause could be linked to numerous disturbances of lower urinary tract. However, the results of most well designed clinical studies do not support use of estrogen or hormone replacement therapy for the treatment of genitourinary symptoms. According to evidence base medicine stress urinary incontinence, overactive bladder syndrome or pelvic organ prolapse are best treated by the surgery or non-hormonal drug therapy.
Rechberger
Tomasz
T
Chair of Gynecology, Medical University of Lublin, Lublin, Poland. rechbergt@yahoo.com
Skorupski
Pawel
P
D004967:Estrogens / Q000008:administration & dosage / Q000502:physiology* / Q000627:therapeutic use; D005260:Female; D012739:Gonadal Steroid Hormones / Q000494:pharmacology / Q000627:therapeutic use; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008297:Male; D053201:Urinary Bladder, Overactive / Q000188:drug therapy / Q000601:surgery; D014549:Urinary Incontinence / Q000188:drug therapy / Q000601:surgery; D014566:Urogenital System / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology; D013520:Urologic Surgical Procedures / Q000379:methods*; D014596:Uterine Prolapse / Q000188:drug therapy / Q000378:metabolism / Q000601:surgery
D004967:Estrogens; D012739:Gonadal Steroid Hormones