title: Electrocardiographic findings of acute organophosphate poisoning.
abstract: In this study, we evaluated 85 patients who presented to our Emergency Department with organophosphate (OP) poisoning and discuss their associated electrocardiographic (ECG) abnormalities. Over a period of 3 years, 85 patients with OP poisoning were included in this retrospective study. ECG analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. The mean age was 32.2 +/- 14.9 years. Sixty percent of the patients were female. The mean corrected QT interval (QTc interval) was 0.435 +/- 0.052 s. Prolongation of the QTc interval (55.5%) was the most common ECG abnormality, followed by sinus tachycardia (31.8%). Elevation of the ST segment and low amplitude T waves were seen in 15 cases (17.6%). Patients with OP poisoning might reveal ECG abnormalities such as QTc interval prolongation or non-specific ST-T changes. QTc interval prolongation cannot be used as a unique predictive factor in determining short-term prognosis in OP poisoning. We found no clear relation between OP poisoning-related malignant ventricular dysrhythmia and QTc interval.
authors.affiliation: Department of Emergency Medicine, Kocatepe University Medical Faculty, Afyonkarahisar, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yurumez
authors.forename: Yucel
authors.initials: Y
authors.lastname: Yavuz
authors.forename: Hayrettin
authors.initials: H
authors.lastname: Saglam
authors.forename: Polat
authors.initials: P
authors.lastname: Durukan
authors.forename: Seda
authors.initials: S
authors.lastname: Ozkan
authors.forename: Okhan
authors.initials: O
authors.lastname: Akdur
authors.forename: Murat
authors.initials: M
authors.lastname: Yucel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000382:Agricultural Workers' Diseases / Q000139:chemically induced* / Q000503:physiopathology*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology*; D002800:Cholinesterase Inhibitors / Q000506:poisoning; D015331:Cohort Studies; D004562:Electrocardiography; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning; D012189:Retrospective Studies; D014421:Turkey; D055815:Young Adult
chemical_list: D002800:Cholinesterase Inhibitors; D007306:Insecticides