title: Peroperative neuromonitoring during carotid endarterectomy in relation to preoperative positron emission tomography findings.
abstract: OBJECTIVE
  To compare stump pressure (SP), transcranial Doppler (TCD), electroencephalography (EEG) and selective shunting during carotid endarterectomy (CEA) with preoperative positron emission tomography (PET) parameters.
  
  
  METHODS
  Preoperative PET measurements and peroperative neuromonitoring were performed in ten patients undergoing CEA for symptomatic carotid artery disease. PET parameters measured were cerebral blood flow (CBF), oxygen extraction fraction (OEF), cerebral oxygen metabolism (CMRO(2)), cerebral blood volume (CBV), mean vascular transit time (MVTT) and cerebral perfusion pressure (CPP). Results of these measurements in ipsilateral medial cerebral artery (MCA), ipsilateral hemisphere and total cerebrum were compared with absolute mean SP, mean SP<40mmHg, TCD, EEG changes and selective shunting.
  
  
  RESULTS
  None of the PET parameters showed any significant correlations with peroperative neuromonitoring findings. There were only trends for correlations of CBF and MVTT with TCD changes and of CPP and CMRO(2) with selective shunting.
  
  
  CONCLUSIONS
  Preoperative PET examinations are not useful for predicting the need for shunting during CEA.
authors.affiliation: Department of General Surgery, Kennemer Gasthuis, Haarlem, The Netherlands. rijbroek@kg.nl
authors.forename: A
authors.initials: A
authors.lastname: Rijbroek
authors.forename: R
authors.initials: R
authors.lastname: Boellaard
authors.forename: E M
authors.initials: EM
authors.lastname: Vriens
authors.forename: A A
authors.initials: AA
authors.lastname: Lammertsma
authors.forename: J A
authors.initials: JA
authors.lastname: Rauwerda
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D001783:Blood Flow Velocity; D001794:Blood Pressure; D001795:Blood Pressure Determination; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D002560:Cerebrovascular Circulation; D003097:Collateral Circulation; D004569:Electroencephalography; D016894:Endarterectomy, Carotid / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D010101:Oxygen Consumption; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011300:Preoperative Care; D012039:Regional Blood Flow; D017585:Ultrasonography, Doppler, Transcranial