[Chemical constituents in unsaponifiable matter from seeds of Trichosanthes hupehensis].
OBJECTIVE
To study the chemical constituents of unsaponifiable matter from the seed oil of Trichosanthes hupehensis.


METHODS
The fatty oil from the seeds of T. hupehensis was extracted with petroleum ether. The saponification was carried out with potassium hydroxide. The unsaponifiable matter was isolated and purified by silica gel column chromatography. Their structures were elucidated by means of MS, IR, UV, and 1H-NMR.


RESULTS
Karounidiol, isokarounidiol, 5-dehydrokarounidiol, 7-oxodihydrokarounidiol, stigmast-7-en-3beta-ol, stigmast-7, 22-dien-3beta-ol, 10alpha-Cucurbitadienol, beta-sitosterol, stigmast-7, 22-dien-3beta-O-beta-D-glucoside were elucidated.


CONCLUSIONS
All of these compounds were found in this plant for the first time.
Xi
Yan-Bin
YB
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Chao
Zhi-Mao
ZM
Wang
Jin
J
D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D029778:Trichosanthes / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification
D010938:Plant Oils; D012855:Sitosterols; D014315:Triterpenes; C088116:karounidiol; C076913:7-oxodihydrokarounidiol; C025473:gamma-sitosterol; D009828:Oleanolic Acid