title: [In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions].
abstract: ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.
authors.affiliation: SOLVO Biotechnológiai Zrt., Szeged.
authors.forename: Akos
authors.initials: A
authors.lastname: Pál
authors.forename: Emese
authors.initials: E
authors.lastname: Kis
authors.forename: Dóra
authors.initials: D
authors.lastname: Méhn
authors.forename: Hristos
authors.initials: H
authors.lastname: Glavinas
authors.forename: Tünde
authors.initials: T
authors.lastname: Nagy
authors.forename: Péter
authors.initials: P
authors.lastname: Mészaros
authors.forename: György
authors.initials: G
authors.lastname: Báthori
authors.forename: Péter
authors.initials: P
authors.lastname: Krajcsi
authors.forename: György
authors.initials: G
authors.lastname: Falkay
mesh_terms: D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D002460:Cell Line; D004347:Drug Interactions; D004358:Drug Therapy; D006801:Humans; D007313:Insecta; D009363:Neoplasm Proteins / Q000187:drug effects / Q000378:metabolism*; D015262:Xenobiotics / Q000493:pharmacokinetics
chemical_list: C116614:ABCG2 protein, human; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters; D009363:Neoplasm Proteins; D015262:Xenobiotics