[Effects of different compressive stress on biological characteristics of condylar chondrocytes of neonatal SD rats].
OBJECTIVE
To investigate the effects of different static compressive stress on the biological characteristics of the mandibular condylar chondrocytes (MCC).


METHODS
The static compressive stress with a magnitude of 12, 24, 36 kPa were exerted on the third passage of MCC for one hour. The MCC was dyed by immunohisto-chemical method. The changes of the expression of collagen type I , II , III and proteoglycan (PG) were evaluated by a pathologic portraits analytic system.


RESULTS
The static compressive stress with a magnitude from 12 to 24 kPa can enforce the expression of collagen type I , II, III and PG of MCC. However, the decrease of expression of collagen type I and PG of MCC was detected when exerted by the static compressive stress with a magnitude from 24 kPa to 36 kPa.


CONCLUSIONS
The static stress of proper magnitude can make MCC more differentiate. However, the static stress of over-magnitude may make the biological characteristics of MCC weaken and express some characteristics of dedifferentiation.
Guo
Wei-Hua
WH
Dept of Orthodontics, College of Stomatology, Kunming Medical College, Kunming 650031, China.
Li
Song
S
Xu
Yun
Y
D000818:Animals; D002478:Cells, Cultured; D019902:Chondrocytes; D024042:Collagen Type I; D008335:Mandibular Condyle; D051381:Rats; D017207:Rats, Sprague-Dawley; D013314:Stress, Mechanical
D024042:Collagen Type I