title: Inefficacy of the cementation of femoral head collapse in glucocorticoid-induced osteonecrosis.
abstract: The objective of this paper was to assess the efficacy of cementation of the femoral head in stage III glucocorticoid-induced osteonecrosis. Ten hips (nine patients) were treated by the injection of low-viscosity cement to reduce the collapse. The follow up included clinical and radiological assessments preoperatively and at 3, 6 and 12 months after surgery. The visual analogue scale (VAS) score, the Lequesne index and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score did not show any significant improvement. Eight of the ten hips showed a worsening of the collapse and required total hip arthroplasty during follow up. The mean time before total hip replacement was 8.6 +/- 7 months. The other two hips did not show any relapse of collapse nor functional worsening at the maximum follow up of 5 years. Our results suggest that cement injection is not a treatment that should be proposed for glucocorticoid-induced osteonecrosis.
authors.affiliation: Department of Rheumatology, Erasme University Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium.
authors.forename: Valérie
authors.initials: V
authors.lastname: Gangji
authors.forename: Marcel
authors.initials: M
authors.lastname: Rooze
authors.forename: Viviane
authors.initials: V
authors.lastname: De Maertelaer
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Hauzeur
mesh_terms: D000328:Adult; D000368:Aged; D001843:Bone Cements; D002484:Cementation / Q000379:methods*; D005260:Female; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000473:pathology / Q000601:surgery*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D010014:Osteolysis / Q000139:chemically induced / Q000473:pathology / Q000601:surgery*; D012720:Severity of Illness Index; D055815:Young Adult
chemical_list: D001843:Bone Cements; D005938:Glucocorticoids