title: [Evaluation of the antifungal effect of a new propiconazole derivative against 64 yeast strains isolated from vaginal mycosis].
abstract: Worldwide, vaginal candidosis represents a significant health problem in women of childbearing age. The aim of this paper is to evaluate under in vitro conditions resembling the vaginal microenvironment, the antifungal activity of a new propiconazole derivative against 64 strains of yeast species isolated from vulvovaginitis. The tests exhibited low MICs for all strains and this finding may be useful in using of this new azole compound for treatment of mycotic vaginitis.
authors.affiliation: Universitatea Petre Andrei Iaşi, Facultatea de Medicină Dentară, Disciplina de Microbiologie.
authors.forename: M
authors.initials: M
authors.lastname: Mareş
authors.forename: Alina
authors.initials: A
authors.lastname: Stefanache
authors.forename: Iuliana
authors.initials: I
authors.lastname: Popovici
authors.forename: V
authors.initials: V
authors.lastname: Valica
authors.forename: D
authors.initials: D
authors.lastname: Buiuc
mesh_terms: D000465:Algorithms; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002175:Candida / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D016896:Treatment Outcome; D014230:Triazoles / Q000494:pharmacology* / Q000627:therapeutic use; D015003:Yeasts / Q000145:classification / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D014230:Triazoles; C045950:propiconazole