title: Autoimmunity and glaucoma.
abstract: Elevated intraocular pressure does not explain glaucoma in all patients, but there is information that autoimmune mechanisms may be involved in this disorder. This review attempts to reveal the findings about specific changes in autoantibody profiles in glaucoma patients and their possible role in glaucoma. Considering that these changes in natural autoimmunity can be found consistently among different study populations, it might be a promising new tool for glaucoma detection.
authors.affiliation: Experimental Ophthalmology, Department of Ophthalmology, Johannes Gutenberg University, Mainz, Germany. grus@eye-research.org
authors.forename: Franz H
authors.initials: FH
authors.lastname: Grus
authors.forename: Stephanie C
authors.initials: SC
authors.lastname: Joachim
authors.forename: Diana
authors.initials: D
authors.lastname: Wuenschig
authors.forename: Jochen
authors.initials: J
authors.lastname: Rieck
authors.forename: Norbert
authors.initials: N
authors.lastname: Pfeiffer
mesh_terms: D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology; D015551:Autoimmunity / Q000502:physiology*; D005901:Glaucoma / Q000276:immunology*; D006801:Humans; D007429:Intraocular Pressure
chemical_list: D001323:Autoantibodies