title: [Development of automatic analysis for dynamic renal function study using computed tomographic (CT) images].
abstract: Determination of the region of interest (ROI) for dynamic renal function has been highly discordant among operators because of the dependence on factors such as the rate of injection of radioactive medicines, constitution, and renal function. To simplify this problem, we developed a computer algorithm that provides automatic analysis for both localization of the kidney and automatic determination of ROIs using computed tomographic (CT) images. The bilateral kidneys were extracted from enhanced CT images, and the CT pixel size was adjusted to dynamic renal function images. The template-matching technique was used for these images, and the kidney renal location was analyzed on additional functional images constructed by dynamic renal function images. As a result, we were able to obtain time-activity curves of both renal function and quantified glomerular filtration rate (GFR). In conclusion, the computer algorithm we developed was considered to provide reliable results, apart from the variability among operators, because of its good reproducibility.
authors.affiliation: Center for Diagnostic Imaging, Kurume University Hospital.
authors.forename: Ryuuji
authors.initials: R
authors.lastname: Ikematsu
authors.forename: Hidemichi
authors.initials: H
authors.lastname: Kawata
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawamura
authors.forename: Hisao
authors.initials: H
authors.lastname: Miura
authors.forename: Teruo
authors.initials: T
authors.lastname: Miyagawa
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ishibashi
authors.forename: Naofumi
authors.initials: N
authors.lastname: Hayabuchi
mesh_terms: D000328:Adult; D000465:Algorithms; D001331:Automation; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D011866:Radioisotope Renography / Q000379:methods*; D016284:Technetium Tc 99m Pentetate; D014057:Tomography, X-Ray Computed
chemical_list: D016284:Technetium Tc 99m Pentetate