title: Vancomycin use in a large teaching hospital in Shiraz, Islamic Republic of Iran, 2003.
abstract: We investigated adherence to the Hospital Infection Control Practice Advisory Committee (HICPAC) guidelines on vancomycin prescription in a large university-affiliated hospital in Shiraz. From August to December 2003, 200 hospitalized patients received vancomycin. For only 12 (6%) of these patients was vancomycin prescribed appropriately according to HICPAC guidelines. The main reasons why vancomycin use did not comply with HICPAC recommendations were: surgical prophylaxis in patients with negative cultures for resistant Gram-positive organisms, no investigation of vancomycin serum levels in patients receiving > 48 hours of vancomycin, vancomycin serum levels not repeated in patients receiving > 1 week of vancomycin, no appropriate adjustment of dosage with respect to serum levels in patients receiving vancomycin.
authors.affiliation: Department of Community Medicine, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. askariam@sums.ac.ir
authors.forename: M
authors.initials: M
authors.lastname: Askarian
authors.forename: O
authors.initials: O
authors.lastname: Assadian
authors.forename: GhR
authors.initials: G
authors.lastname: Safaee
authors.forename: A
authors.initials: A
authors.lastname: Golkar
authors.forename: S
authors.initials: S
authors.lastname: Namazi
authors.forename: M R
authors.initials: MR
authors.lastname: Movahed
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000592:standards / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D016903:Drug Monitoring / Q000592:standards; D011307:Drug Prescriptions / Q000592:standards / Q000706:statistics & numerical data; D017723:Drug Utilization Review; D005260:Female; D019983:Guideline Adherence / Q000458:organization & administration; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D017053:Infection Control / Q000458:organization & administration; D007492:Iran; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000458:organization & administration*; D014640:Vancomycin / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin