title: Survey of furan in heat processed foods by headspace gas chromatography/mass spectrometry and estimated adult exposure.
abstract: Furan is a suspected human carcinogen that is formed in some processed foods at low ng per g levels. Recent improvements in analytical methodology and scientific instrumentation have made it possible to accurately measure the amount of furan in a wide variety of foods. Results from analysis of more than 300 processed foods are presented. Furan was found at levels ranging from non-detectable (LOD, 0.2-0.9 ng g(-1)) to over 100 ng g(-1). Exposure estimates for several adult food types were calculated, with brewed coffee being the major source of furan in the adult diet (0.15 microg kg(-1) body weight day(-1)). Estimates of mean exposure to furan for different subpopulations were calculated. For consumers 2 years and older, the intake is estimated to be about 0.2 microg kg(-1) body weight day(-1).
authors.affiliation: Food and Drug Administration-CFSAN, College Park, MD 20740, USA. kim.morehouse@fda.hhs.gov
authors.forename: Kim M
authors.initials: KM
authors.lastname: Morehouse
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Nyman
authors.forename: Timothy P
authors.initials: TP
authors.lastname: McNeal
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Dinovi
authors.forename: Gracia A
authors.initials: GA
authors.lastname: Perfetti
mesh_terms: D000328:Adult; D002273:Carcinogens / Q000032:analysis* / Q000633:toxicity; D003069:Coffee; D005506:Food Contamination / Q000032:analysis*; D005511:Food Handling; D005663:Furans / Q000032:analysis* / Q000633:toxicity; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006358:Hot Temperature; D006801:Humans; D008461:Meat Products
chemical_list: D002273:Carcinogens; D003069:Coffee; D005663:Furans; C039281:furan