Antimicrobials as a contributory factor in oral candidosis--a brief overview.
The advent of the human immunodeficiency virus infection and the increasing prevalence of compromised individuals in the community due to modern therapeutic advances have resulted in a resurgence of opportunistic infections, including oral candidosis, which is by far the most common oral fungal infection in man. Broad-spectrum antibiotics used in the treatment of a wide range of disease conditions have also been attributed as a predisposing factor of oral candidosis. In this mini review we discuss the research findings on the relationship between antibiotics and oral candidosis and possible mechanisms of pathogenicity following such therapy.
Soysa
N S
NS
Division of Pharmacology, Department of Oral Medicine and Periodontology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka. niroshanis@pdn.ac.lk
Samaranayake
L P
LP
Ellepola
A N B
AN
D000818:Animals; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002180:Candidiasis, Oral / Q000139:chemically induced* / Q000382:microbiology; D004195:Disease Models, Animal; D006801:Humans; D016867:Immunocompromised Host; D009894:Opportunistic Infections / Q000139:chemically induced* / Q000382:microbiology
D000890:Anti-Infective Agents