title: Congenital and acquired brain injury. 1. Epidemiology, pathophysiology, prognostication, innovative treatments, and prevention.
abstract: This self-directed learning module reviews the current epidemiology of traumatic brain injury (TBI), its pathophysiology, prognostication after injury, currently available innovative early approaches to diagnosis and treatment, and effective methods of prevention. It is intended to provide the rehabilitation clinician with current knowledge to accurately inform patients, families, significant others, referring physicians, and payers and to aid in clinical decision making while caring for patients after TBI.
  
  
  OBJECTIVE
  To describe current knowledge in traumatic brain injury epidemiology, pathophysiology, prognostication, acute treatment, and prevention.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Rochester, MN, USA. brown.allen@mayo.edu.
authors.forename: Allen W
authors.initials: AW
authors.lastname: Brown
authors.forename: Elie P
authors.initials: EP
authors.lastname: Elovic
authors.forename: Sunil
authors.initials: S
authors.lastname: Kothari
authors.forename: Steven R
authors.initials: SR
authors.lastname: Flanagan
authors.forename: Christina
authors.initials: C
authors.lastname: Kwasnica
mesh_terms: D001930:Brain Injuries / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D015994:Incidence; D009043:Motor Activity / Q000502:physiology*; D010810:Physical and Rehabilitation Medicine / Q000379:methods*; D017410:Practice Guidelines as Topic; D014193:Trauma Centers; D014481:United States / Q000453:epidemiology