title: [Clinical effects of calcium hydroxide-based sealer on chronic apical periodontitis].
abstract: OBJECTIVE
  To evaluate the results of calcium hydroxide-based sealer Sealapex in the treatment of chronic apical periodontitis.
  
  
  METHODS
  A total of 100 cases with chronic apical periodontitis were included and divided into two groups, calcium hydroxide sealer (Sealapex) group and ZOE sealer group, and Sealapex and ZOE sealer were respectively used. All cases were followed up for two years after treatment and the clinical results compared between the two groups. The evaluation was based on clinical examination and radiographic assessment using periapical index (PAI) and digital subtraction radiography (DSR) technique.
  
  
  RESULTS
  There was no significant difference between the ZOE group and Sealapex group in overall healing rates and mean quantitative analysis at 3 months and 2 years after treatment (P = 0.206, 0.776). A correlation was found between PAI and DSR (P < 0.01, gamma = 0.58).
  
  
  CONCLUSIONS
  Sealapex sealer could obtain satisfactory effects for the treatment of chronic apical periodontitis. The combination of DSR and PAI methods was able to monitor the radiographic bone changes of periapical disease.
authors.affiliation: Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Yu-Hong
authors.initials: YH
authors.lastname: Liang
authors.forename: Gang
authors.initials: G
authors.lastname: Zhang
authors.forename: Jia-de
authors.initials: JD
authors.lastname: Wang
mesh_terms: D002126:Calcium Hydroxide / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010485:Periapical Periodontitis / Q000628:therapy*; D010512:Periodontal Index; D019252:Radiography, Dental, Digital; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D012387:Root Canal Filling Materials; D002126:Calcium Hydroxide