title: [Pregnancy and delivery in a patient with Willebrand's disease. Apropos of a case].
abstract: Willebrand's disease is the most frequent inborn coagulopathy and type 3 is its most severe form. Pregnancy and delivery are critical events in women with Willebrand's disease of type 3. Prophylactic treatment for delivery and early postpartum period is recommended. We report the management of pregnancy and successful delivery of a 32-year-old woman with type 3. Prophylactic treatment with 2000 IU of Willebrand's disease factor (WdF) was given twice a day during the delivery day and the day after, and 1000 IU per day during the next three days. The patient did not show any spontaneous metrorrhagia but anemia. No bleeding was observed in the newborn.
authors.affiliation: Laboratoire d'hématologie, CHU Ibn Rochd, Casablanca, Maroc. sihamc@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Cherkaoui
authors.forename: A
authors.initials: A
authors.lastname: Laaloui
authors.forename: S
authors.initials: S
authors.lastname: Faiz
authors.forename: N
authors.initials: N
authors.lastname: Benchemsi
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002585:Cesarean Section; D003241:Consanguinity; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010923:Placenta Previa / Q000601:surgery; D010974:Platelet Aggregation; D006473:Postpartum Hemorrhage / Q000517:prevention & control*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy* / Q000235:genetics; D014592:Uterine Hemorrhage / Q000517:prevention & control*; D014842:von Willebrand Diseases / Q000150:complications / Q000188:drug therapy*; D014841:von Willebrand Factor / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014841:von Willebrand Factor; D003894:Deamino Arginine Vasopressin