title: Sinus thrombosis in idiopathic hypereosinophilic syndrome causing fatal cerebral haemorrhage.
abstract: Idiopathic hypereosinophilic syndrome (HES) is a leukoproliferative disorder that is characterized by sustained overproduction of eosinophils and a trend towards damage to specific organs, usually the cardiovascular system. We report the case of a 76-year-old woman who was affected by idiopathic HES, which had an unusual and rapidly fatal course. Sinus thrombosis in the transverse and sigmoid sinuses was evident on cranial CT and CT angiography. In our review of the English-language literature we were unable to find any previously published direct images of sinus thrombosis in idiopathic HES.
authors.affiliation: Department of Neurosurgery, Aomori Prefectural Central Hospital, 2-1-1 Higashitsukurimichi, Aomori City, Aomori 030-0913, Japan. numa@jeans.ocn.ne.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Numagami
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tomita
authors.forename: Kensuke
authors.initials: K
authors.lastname: Murakami
authors.forename: Iwasaki
authors.initials: I
authors.lastname: Masaki
authors.forename: Komei
authors.initials: K
authors.lastname: Kubo
authors.forename: Nishijima
authors.initials: N
authors.lastname: Michiharu
mesh_terms: D000368:Aged; D002543:Cerebral Hemorrhage / Q000209:etiology*; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000209:etiology*; D014057:Tomography, X-Ray Computed / Q000379:methods