title: [Severe thrombocytosis and leukocytosis associated with iron deficiency anaemia: a case-report].
abstract: Reactive thrombocytosis (secondary thrombocytosis) is frequent and typically moderate. We report a case of extreme thrombocytosis and leukocytosis secondary to an iron deficiency anemia. A 21-year-old woman is admitted in emergency department for acute headache. Biological assessment reveals a severe microcytic anaemia (5.4 g/dL) with thrombocytosis (2500 giga/L) and leukocytosis (35 giga/L) leading to multiple diagnosis hypotheses. Finally, biological evaluation concludes to a diagnosis of iron deficiency anaemia related to insufficient oral intake and menorrhagia. Reactive hyperleukocytosis and thrombocytosis rapidly resolved with iron supplementation. This case is a reminder that iron deficiency-related thrombocytosis can sometimes be severe. However, the associated reactive leukocytosis is quite exceptional.
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France.
authors.forename: F
authors.initials: F
authors.lastname: Bernard
authors.forename: V
authors.initials: V
authors.lastname: Baccini
authors.forename: D
authors.initials: D
authors.lastname: Bagneres
authors.forename: P
authors.initials: P
authors.lastname: Rossi
authors.forename: A L
authors.initials: AL
authors.lastname: Demoux
authors.forename: S
authors.initials: S
authors.lastname: Bonin-Guillaume
authors.forename: Y
authors.initials: Y
authors.lastname: Frances
authors.forename: B
authors.initials: B
authors.lastname: Granel
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000150:complications*; D005260:Female; D006801:Humans; D007964:Leukocytosis / Q000209:etiology*; D012720:Severity of Illness Index; D013922:Thrombocytosis / Q000209:etiology*