title: Successful treatment of pulmonary mucormycosis in a renal transplant recipient with limited pulmonary reserve by combined medical and surgical therapy.
abstract: Mucormycosis is a rare opportunistic fungal infection in renal transplant recipients which is associated with exceedingly high mortality when inadequately treated. Risk factors for this infection include diabetes, neutropaenia and immunosuppression. We report a case of pulmonary mucormycosis in a renal allograft recipient with type 2 diabetes and limited pulmonary reserve. The patient was successfully treated with lobectomy and liposomal amphotericin B with preservation of pulmonary and allograft functions. Early recognition of this infection is warranted before dissemination, which carries a poor prognosis.
authors.affiliation: Department of Nephrology and Transplantation Services, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia. jordan.li@fmc.sa.gov.au
authors.forename: Jordan Y Z
authors.initials: JY
authors.lastname: Li
authors.forename: Tuck Y
authors.initials: TY
authors.lastname: Yong
authors.forename: Craig A
authors.initials: CA
authors.lastname: Jurisevic
authors.forename: Graeme R
authors.initials: GR
authors.lastname: Russ
authors.forename: David I
authors.initials: DI
authors.lastname: Grove
authors.forename: P Toby H
authors.initials: PT
authors.lastname: Coates
authors.forename: Alex P S
authors.initials: AP
authors.lastname: Disney
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000276:immunology*; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000276:immunology / Q000601:surgery*; D008875:Middle Aged; D009091:Mucormycosis / Q000188:drug therapy / Q000276:immunology / Q000601:surgery*; D011013:Pneumonectomy; D020127:Recovery of Function
chemical_list: D000935:Antifungal Agents