title: [Study on chemical constituents from rhizomes of Actaea asiatica].
abstract: OBJECTIVE
  To investigate the chemical constituents of the rhizomes of Actaea asiatica in order to obtain a more comprehensive understanding of its effective components.
  
  
  METHODS
  Compounds were separated by silica gel chromatography, RP-C18 chromatography and semi-preparative high performance liquid chromatography, and their structures were established by spectral analysis and chemical evidence.
  
  
  RESULTS
  Six compounds were isolated from the ethyl acetate extract. Their structures were identified as 25-O-acetylcimigenol (1), 12beta-hydroxycimigenol (2), 23-epi-26-deoxyactein (3), 27-deoxyacetylacteol (4), 26-deoxycimicifugenin (5) and beta-sitosterol (6).
  
  
  CONCLUSIONS
  All these compounds mentioned above were isolated from the plant for the first time.
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100094, China.
authors.forename: Jing-Chun
authors.initials: JC
authors.lastname: Gao
authors.forename: Jin-Chao
authors.initials: JC
authors.lastname: Zhang
authors.forename: Yao
authors.initials: Y
authors.lastname: Chen
authors.forename: Meng-Su
authors.initials: MS
authors.lastname: Yang
authors.forename: Pei-Gen
authors.initials: PG
authors.lastname: Xiao
mesh_terms: D031842:Actaea / Q000737:chemistry*; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012503:Saponins; D012855:Sitosterols; D014315:Triterpenes; D007810:Lanosterol; C457248:23-epi-26-deoxyactein; C025473:gamma-sitosterol