[A method of perfluorinated organic compounds in drinking water determinated by HPLC-MS/MS].
OBJECTIVE
To establish a method of perfluorinated organic compounds (POCs) in drinking water determinated by HPLC-MS/MS.


METHODS
The contents of selected POCs (i. e., perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA) and perfluorodecanoate (PFDA)) in water samples were extracted by the C18 solid-phase extraction (SPE). The extraction samples were then identified and quantitated by high performance liquid chromatography-negative electrospray mass spectrometry (HPLC-ESI-MS/MS).


RESULTS
Linear calibration curves were obtained at the concentration ranges from 50 pg/ml to 1000 pg/ml (the correlation coefficients were above 0.99). The average recoveries for PFOA, PFOS and PFDA spiked in water ranged from 65 to 111% and their relative standard were between 3.6% and 14.6%. The limit of quantification (LOQ) of the method was 8 pg/g.


CONCLUSIONS
The method for determination of POCs in drinking water could be simple, sensitive and accurate.
Wang
Chuanxian
C
Shanghai Entry-Exit Inspection and Quarantine Bureau, Beijing 200335, China.
Guo
Dehua
D
Li
Bo
B
Wang
Min
M
D017738:Alkanesulfonic Acids / Q000032:analysis; D002210:Caprylates / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005466:Fluorocarbons / Q000032:analysis*; D007850:Lauric Acids / Q000032:analysis*; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis; D014881:Water Supply / Q000032:analysis*
D017738:Alkanesulfonic Acids; D002210:Caprylates; D005466:Fluorocarbons; D007850:Lauric Acids; D014874:Water Pollutants, Chemical; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid; C522391:perfluorododecanoic acid