title: Prescription medication misuse and substance use disorder in VA primary care patients with chronic pain.
abstract: OBJECTIVE
  The goal of this paper was to examine the relationship between history of substance use disorder (SUD) and self-reported prescription medication misuse in 127 primary care patients who receive opioid medications for treatment of chronic pain.
  
  
  METHODS
  Participants completed measures of pain location, pain intensity, disability due to pain, and misuse of prescription medications. Other measures included demographic characteristics, psychiatric symptomatology and quality of life.
  
  
  RESULTS
  Seventy-eight percent of participants reported at least one indicator of medication misuse in the prior year. After adjusting for age and clinical factors (pain severity, depression severity, current alcohol or substance use disorder), participants with SUD history were significantly more likely than participants without SUD history to report borrowing pain medications from others (OR=6.62, 95% CI=1.4-30.7) and requesting an early refill of pain medication (OR=3.86, 95% CI=1.5-9.6).
  
  
  CONCLUSIONS
  Misuse of prescription medications is a concern among primary care patients with chronic pain. Participants with a lifetime history of SUD are more likely to endorse some aberrant medication-related behaviors. Patients with SUD histories should be carefully evaluated for medication misuse potential and may require more intense assessment and follow-up.
authors.affiliation: Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97219, USA. benjamin.morasco@va.gov
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Morasco
authors.forename: Steven K
authors.initials: SK
authors.lastname: Dobscha
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects; D002908:Chronic Disease; D011307:Drug Prescriptions; D005260:Female; D006787:Hospitals, Veterans; D006801:Humans; D008297:Male; D008875:Middle Aged; D009922:Oregon / Q000453:epidemiology; D010146:Pain / Q000188:drug therapy*; D004364:Pharmaceutical Preparations; D011320:Primary Health Care; D019966:Substance-Related Disorders / Q000453:epidemiology*; D011795:Surveys and Questionnaires
chemical_list: D000701:Analgesics, Opioid; D004364:Pharmaceutical Preparations