title: Diagnosis and management of lipomatous tumors.
abstract: Lipomatous tumors range from benign lipomas to high-grade liposarcomas. Liposarcomas are classified into five histologic subtypes: well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic, which differ in outcomes and patterns of recurrence. Surgical resection is the mainstay of curative treatment; however, large, high grade liposarcomas may benefit from multimodality treatment with chemotherapy and radiation. A histologic-subtype specific nomogram provides accurate survival predictions. Prospective randomized clinical trials will continue to improve our care of patients with liposarcoma.
authors.affiliation: Department of Surgery, David Grant United States Air Force Medical Center, Travis Air Force Base, California 94535, USA. kimberlydalal@yahoo.com
authors.forename: Kimberly Moore
authors.initials: KM
authors.lastname: Dalal
authors.forename: Cristina R
authors.initials: CR
authors.lastname: Antonescu
authors.forename: Samuel
authors.initials: S
authors.lastname: Singer
mesh_terms: D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D008067:Lipoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D011379:Prognosis