title: Hodgkin lymphoma as a complication of primary Sjögren's syndrome.
abstract: Sjögren's syndrome (SS) is a chronic autoimmune disease that is characterized by lymphocytic infiltration of the exocrine glands, mainly the salivary and lachrymal glands, usually manifesting with xerostomia and xerophthalmia. Around 50% of patients with primary SS develop systemic complications, lymphoma being the most feared of these. The majority of these neoplasias originate from B cells and are of the non-Hodgkin type. We describe here a rare case of SS in which the patient developed a Hodgkin lymphoma. We also review the literature on this subject.
authors.affiliation: Rheumatology Service, Hospital Santa Izabel (HSI), Salvador, Bahia, Brazil.
authors.forename: Isabella
authors.initials: I
authors.lastname: Lima
authors.forename: Ana Suellen B
authors.initials: AS
authors.lastname: Carneiro
authors.forename: Caroline Alencar
authors.initials: CA
authors.lastname: Amorim
authors.forename: Mittermayer Barreto
authors.initials: MB
authors.lastname: Santiago
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use; D003606:Dacarbazine / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006689:Hodgkin Disease / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D010306:Parotid Gland / Q000473:pathology; D016539:Reed-Sternberg Cells / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000473:pathology; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D001761:Bleomycin; D014747:Vinblastine; D003606:Dacarbazine; D004317:Doxorubicin