title: Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community.
abstract: The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds ratio for diagnosis of major depressive disorder (4.7, 95% confidence interval [1.6, 14.5]) and panic disorder (12.9 [3.6, 46.0]) and comorbidity of major depressive disorder and panic disorder (9.7 [1.4, 69.0]) in the past 12 months suggested a strong association between restless legs syndrome and major depressive disorder and/or panic disorder.
authors.affiliation: Division of Geriatric Psychiatry and Neuropsychiartry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Hochang@jhmi.edu
authors.forename: Hochang B
authors.initials: HB
authors.lastname: Lee
authors.forename: Wayne A
authors.initials: WA
authors.lastname: Hening
authors.forename: Richard P
authors.initials: RP
authors.lastname: Allen
authors.forename: Amanda E
authors.initials: AE
authors.lastname: Kalaydjian
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Earley
authors.forename: William W
authors.initials: WW
authors.lastname: Eaton
authors.forename: Constantine G
authors.initials: CG
authors.lastname: Lyketsos
mesh_terms: D000368:Aged; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003865:Major Depressive Disorder / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016584:Panic Disorder / Q000453:epidemiology*; D012111:Residence Characteristics; D012148:Restless Legs Syndrome / Q000453:epidemiology*; D011795:Surveys and Questionnaires