title: [Central serous chorioretinopathy as an extradigestive manifestation of Helicobacter pylori gastric infection].
abstract: OBJECTIVE
  Helicobacter pylori (HP) gastric infection has been implicated as an important factor in occlusive arterial pathology. Nowadays, it is suspected that central serous chorioretinopathy (CSC) is due to a multifocal vascular occlusive disease of the choriocapillaris. The aim of this study was to determine the relation between gastric HP infection and CSC.
  
  
  METHODS
  We evaluated a group of 16 patients with CSC and 20 controls. HP infection was assessed by the 13C-urea breath test (UBT). Clinical CSC diagnosis was confirmed by fundus biomicroscopy and fluorescein angiography.
  
  
  RESULTS
  Out of 16 patients with CSC, 11 (68.75%) were males and 5 (31.25%) females, with a mean age of 46.3 years. HP infection was positive in 11 patients (68.75%) and negative in 5 (31.25%). Men were HP-positive (HP+) in 72.7% of cases, compared to women who were HP+ in 60% of cases. The difference in prevalence of HP between the CSC-group (68.75%) and the control-group (30%) was found to be statistically significant (p< 0.05). HP+ patients had more gastric pain than HP negative (HP-) patients (72.73% vs 20%).
  
  
  CONCLUSIONS
  These results indicate a possible statistical association between Helicobacter pylori gastric infection and CSC. HP should thus be considered a risk factor in CSC patients.
authors.affiliation: Hospital General, Medina del Campo, Valladolid, Spain. vasensio@hmdc.sacyl.es
authors.forename: V M
authors.initials: VM
authors.lastname: Asensio-Sánchez
authors.forename: B
authors.initials: B
authors.lastname: Rodríguez-Delgado
authors.forename: E
authors.initials: E
authors.lastname: García-Herrero
authors.forename: V
authors.initials: V
authors.lastname: Cabo-Vaquera
authors.forename: C
authors.initials: C
authors.lastname: García-Loygorri
mesh_terms: D015862:Choroid Diseases / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000382:microbiology*