Three new nardosinane Type Sesquiterpenes from an Indonesian Soft Coral Nephthea sp.
Three new sesquiterpenes, 2-deoxy-7-O-methyllemnacarnol (1), 2-deoxy-12 alpha-ethoxy-7-O-methyllemnacarnol (2), and 2-deoxy-12 alpha-methoxy-7-O-methyllemnacarnol (3), were isolated from a soft coral Nephthea sp. collected in Indonesia, together with five known sesquiterpenes. The structures of the new compounds were assigned on the basis of their spectroscopic data.
Kapojos
Magie Melanie
MM
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Minato-ku, Tokyo 108-8477, Japan.
Mangindaan
Remy Emile Petrus
RE
Nakazawa
Takahiro
T
Oda
Taiko
T
Ukai
Kazuyo
K
Namikoshi
Michio
M
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D049109:Cell Proliferation / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D007214:Indonesia; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
C528523:2-deoxy-12 alpha-ethoxy-7-O-methyllemnacarnol; C528524:2-deoxy-12 alpha-methoxy-7-O-methyllemnacarnol; C528522:2-deoxy-7-O-methyllemnacarnol; D000970:Antineoplastic Agents; D012717:Sesquiterpenes