title: Aortic valve replacement with simultaneous chest wall reconstruction for radiation-induced sarcoma.
abstract: Sarcomas, a rare complication of radiotherapy for breast carcinoma, have a poor prognosis. We describe a lady with previous mantle radiotherapy exposure, who developed a radiation-induced chest wall sarcoma. She underwent simultaneous aortic valve replacement (AVR) for severe aortic stenosis and excision of the sarcoma. Chest wall reconstruction was achieved with a composite marlex cement plate and a pedicled latissimus dorsi muscle flap.
authors.affiliation: Department of Cardiothoracic Surgery, Queen Elizabeth Hospital, University Hospital Birmingham NHS Trust, United Kingdom.
authors.forename: Anand
authors.initials: A
authors.lastname: Sachithanandan
authors.forename: Uday
authors.initials: U
authors.lastname: Dandekar
authors.forename: Robert
authors.initials: R
authors.lastname: Grimer
authors.forename: Francis
authors.initials: F
authors.lastname: Peart
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Rooney
mesh_terms: D001024:Aortic Valve Stenosis / Q000601:surgery*; D001943:Breast Neoplasms / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000628:therapy; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D009381:Neoplasms, Radiation-Induced / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods; D012509:Sarcoma / Q000209:etiology / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000209:etiology / Q000601:surgery*; D013899:Thoracic Neoplasms / Q000601:surgery; D035441:Thoracic Wall / Q000601:surgery*; D016896:Treatment Outcome