title: Quantized current blockade and hydrodynamic correlations in biopolymer translocation through nanopores: evidence from multiscale simulations.
abstract: We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent using an innovative multiscale methodology that treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding up the translocation process.
authors.affiliation: Istituto Applicazioni Calcolo, CNR, Viale del Policlinico 137, 00161 Roma, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Bernaschi
authors.forename: Simone
authors.initials: S
authors.lastname: Melchionna
authors.forename: Sauro
authors.initials: S
authors.lastname: Succi
authors.forename: Maria
authors.initials: M
authors.lastname: Fyta
authors.forename: Efthimios
authors.initials: E
authors.lastname: Kaxiras