title: [Pathogenesis and prevention strategies of indirect injured cataract formation after vitrectomy].
abstract: Vitrectomy has been widely used in medical practice, especially in treatment of diseases such as vitreous body diseases, retinal diseases and ocular injury. Epidemiological studies have indicated that under the circumstance of injuring the lens indirectly after vitrectomy, the incidence of nuclear cataract is obviously increasing, the mechanism and the prevention as well as cure of which is still the live topic in this field. Many studies had manifested that the main mechanism of the high incidence of cataract after vitrectomy included the physical and chemical changes of vitreous body, time of operation, age of patients, diseases of the eye, and uveitis after vitrectomy, etc. The most important factor is that vitrectomy increased oxygen exposure to the lens. Therefore, the measure of decreasing oxygen concentration and the treatment of Zinc-desferrioxamine may reduce the incidence of cataract, which provides a new way for the prevention and treatment of cataract after vitrectomy.
authors.affiliation: Department of Ophthalmology, Tangdu Hospital, The 4th Military Medical University, Xi' an 710038, China.
authors.forename: Xiaocui
authors.initials: X
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Yan
mesh_terms: D002386:Cataract / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D007908:Lens, Crystalline / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D014821:Vitrectomy / Q000009:adverse effects*
chemical_list: D010100:Oxygen