[Study on extraction and drying of Ligusticum chuanxiong in Gan-ning Granule].
OBJECTIVE
To find out the optimum extract process for Ligusticum chuanxiong in Gan-ning Granule, and studyed the methods of concentration and dry for the extract.


METHODS
With the yield of ferulic acid as the assessment index, to optimize the 80% alcohol totalling, extracting times and circumfluence time for extract process by the orthogonal design, to optimize the inlet-air temperature, feed speed and density of feed for spry drying by the orthogonal design.


RESULTS
The optimum procedure was the ferulic acid were extracted for 1 hour with 3 times of 80% alcohol. While extracting times effected it most porminently. The optimal processing conditions of spry drying were inlet-air temperature 120 degrees C, feed speed 8.5 mL x min(-1) and density of feed 1.15, While feed speed effected it most porminently.


CONCLUSIONS
The experimental results provide the basis for the extraction process and drying process of the ferulic acid in ligusticum chuanxiong.
Ding
Yuan-Quan
YQ
Medical Technical Stuff Training Base of Shenyang Military Area, Liaoning dalian 116017, China. 187dyq@163.com
Wan
Shao-Hui
SH
Xu
Qi-Tai
QT
Kang
Ting-Guo
TG
D003373:Coumaric Acids / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D003890:Desiccation / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D030004:Ligusticum / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods
D003373:Coumaric Acids; D004365:Drugs, Chinese Herbal; C004999:ferulic acid