The atypical small GTPase RhoH : a novel role in T cell development.
Small GTPases (G-proteins) play important roles in various signal transduction pathways by working as molecular switches. Among them, some of these GTPases don't have functional features of typical GTPases, therefore they are called "atypical GTPases". Recently, these less known atypical Rho GTPases have received increased attention. This review will focus on the novel aspects of biological function of atypical Rho GTPases, especially a newly found function of RhoH on signal transduction in T cell development.
Suzuki
Harumi
H
Department of Pathology, Research Institute, International Medical Center of Japan.
Oda
Hiroyo
H
D000818:Animals; D051379:Mice; D015398:Signal Transduction / Q000502:physiology*; D013601:T-Lymphocytes / Q000502:physiology*; D020741:rho GTP-Binding Proteins / Q000502:physiology*
D020741:rho GTP-Binding Proteins