title: Clinical course and outcomes of methamphetamine-dependent adults with psychosis.
abstract: Little is known about the association between psychosis and treatment outcomes in methamphetamine (MA) users. Using data from 526 adults in the largest psychosocial clinical trial of MA users conducted to date, this study examined psychiatric, substance use, and functional outcomes of MA users with concomitant psychotic illness 3 years after treatment. The presence of a psychotic disorder was associated with increased health service utilization and higher levels of psychiatric symptomatology across multiple domains over time. MA users with co-occurring psychotic illness may therefore benefit from early psychosocial and/or pharmacologic interventions to address psychiatric symptoms.
authors.affiliation: Integrated Substance Abuse Programs, David Geffen School of Medicine at UCLA, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, USA. sglasner@ucla.edu
authors.forename: Suzette
authors.initials: S
authors.lastname: Glasner-Edwards
authors.forename: Larissa J
authors.initials: LJ
authors.lastname: Mooney
authors.forename: Patricia
authors.initials: P
authors.lastname: Marinelli-Casey
authors.forename: Maureen
authors.initials: M
authors.lastname: Hillhouse
authors.forename: Alfonso
authors.initials: A
authors.lastname: Ang
authors.forename: Richard
authors.initials: R
authors.lastname: Rawson
mesh_terms: D000328:Adult; D019969:Amphetamine-Related Disorders / Q000150:complications / Q000534:rehabilitation*; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008605:Mental Health Services / Q000706:statistics & numerical data; D008694:Methamphetamine / Q000009:adverse effects*; D011618:Psychotic Disorders / Q000150:complications*; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D008694:Methamphetamine