title: Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry.
abstract: Phase retardation of in vivo human retinal nerve fiber layer (RNFL) is quantitatively measured by two methods--polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) and scanning laser polarimetry (SLP). An en face cumulative phase retardation map is calculated from the three-dimensional (3-D) phase retardation volume of healthy and glaucomatous eyes measured by PS-SD-OCT. It is shown that the phase retardation curves around the optic nerve head measured by PS-SD-OCT and SLP have similar values except near the retinal blood vessels. PS-SD-OCT can measure the cumulative phase retardation of RNFL as well as SLP, which will allow the evaluation of RNFL for glaucomatous eyes.
authors.affiliation: University of Tsukuba, Computational Optics Group, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan. yamanari@optlab2.bk.tsukuba.ac.jp
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamanari
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
authors.forename: Shuichi
authors.initials: S
authors.lastname: Makita
authors.forename: Toyohiko
authors.initials: T
authors.lastname: Yatagai
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yasuno
mesh_terms: D000328:Adult; D005901:Glaucoma / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D018613:Microscopy, Confocal / Q000379:methods*; D008859:Microscopy, Polarization / Q000379:methods*; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*