[Surface-enhanced Raman spectra of natural tissue and cancerous tissue of lung].
Surface-enhanced Raman spectra of natural tissue and cancerous tissue of lung from 300 to 1700 cm(-1) were measured. In the cancerous tissue of lung, the orderly conformations of amides III and amides I of the main chains in protein such as alpha-helix, beta-corner and no rules curly were damaged seriously; conversely, the extendable vibration of skeleton C-N and skeleton C-C increased. Side chains change became complicated. In general, the content of nucleic acids increases in the cancer tissue of lung. The lengthways conformations of lecithoid chains is out-of-order in the cancerous tissue of lung compared with the natural ones.
Liu
Yan-nan
YN
Photonics Center of School of Physics, Nankai University, Tianjin 300071, China. nklyn@mail.nankai.edu.cn
Zou
Zu-quan
ZQ
Liu
Yan-qing
YQ
Xu
Xiao-xuan
XX
Yu
Gang
G
Zhang
Cun-zhou
CZ
D000588:Amines / Q000032:analysis; D006801:Humans; D008168:Lung / Q000737:chemistry* / Q000473:pathology; D008175:Lung Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods*
D000588:Amines; D011506:Proteins