A long-term durable remission with high-dose therapy and autologous stem cell transplant for stage IVB HIV-associated Hodgkins disease.
A 44-year-old man with relapsed HIV-associated stage IV nodular sclerosing Hodgkin's disease underwent high-dose therapy with autologous stem cell transplantation. The transplant was uncomplicated and the patient remains in complete remission at 59 months. Autologous stem cell transplantation is safe in HIV patients and can achieve long-term durable remissions in Hodgkin's disease.
Gabriel
Ian
I
Department of Clinical Haematology, Hammersmith Hospital, London, UK.
Apperley
Jane
J
Bower
Mark
M
Chaidos
Aristeidis
A
Gazzard
Brian
B
Giles
Chrissy
C
Kew
Andrea
A
Nelson
Mark
M
Kanfer
Ed
E
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D023241:Antiretroviral Therapy, Highly Active; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D008130:Lomustine / Q000008:administration & dosage; D016483:Lymphoma, AIDS-Related / Q000628:therapy*; D008297:Male; D012074:Remission Induction / Q000379:methods; D014182:Transplantation, Autologous
D003561:Cytarabine; D005047:Etoposide; D008130:Lomustine; D003520:Cyclophosphamide