title: Capnellenes from the Formosan soft coral Capnella imbricata.
abstract: Three anti-inflammatory sesquiterpenes, Delta (9(12))-capnellene-8beta,10alpha-diol ( 1), 8alpha-acetoxy-Delta (9(12))-capnellene-10alpha-ol ( 2), and Delta (9(12))-capnellene-10alpha-ol-8-one ( 3), five new sesquiterpenes, Delta (9(12))-capnellene-8beta,15-diol ( 4), Delta (9(12))-capnellene-8beta,10alpha,13-triol ( 5), Delta (9(10))-capnellene-12-ol-8-one ( 6), 8beta,10alpha-diacetoxy-Delta (9(12))-capnellene ( 7), and 8beta-acetoxy-Delta (9(12))-capnellene ( 8), and a known sesquiterpene, Delta (9(12))-capnellene-8beta-ol ( 9), were isolated from the acetone/methylene chloride extracts of the Formosan soft coral Capnella imbricata. The structures of these compounds were elucidated by extensive spectroscopic analysis.
authors.affiliation: Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China.
authors.forename: Chin-Hsiang
authors.initials: CH
authors.lastname: Chang
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Wen
authors.forename: Shang-Kwei
authors.initials: SK
authors.lastname: Wang
authors.forename: Chang-Yih
authors.initials: CY
authors.lastname: Duh
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D051379:Mice; D015394:Molecular Structure; D052247:Nitric Oxide Synthase Type II / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013624:Taiwan
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D008070:Lipopolysaccharides; D012717:Sesquiterpenes; D052247:Nitric Oxide Synthase Type II