title: Outcome of one-visit and two-visit endodontic treatment of necrotic teeth with apical periodontitis: a randomized controlled trial with one-year evaluation.
abstract: The choice of one-visit versus two-visit root canal therapy for necrotic teeth with apical periodontitis is a source of current debate. The primary objective of this randomized controlled clinical trial was to compare radiographic evidence of periapical healing after root canal therapy completed in one visit or two visits with an interim calcium hydroxide/chlorhexidine paste dressing. Ninety-seven patients met the inclusion criteria and consented to participate in this study. Patients were randomly assigned to either the one-visit or two-visit group, and root canal therapy was performed with a standardized protocol. Patients in the two-visit group received an intracanal dressing of calcium hydroxide/chlorhexidine paste. Sixty-three patients, 33 in the one-visit group and 30 in the two-visit group, were evaluated at 12 months. The primary outcome measure was change in apical bone density by using the periapical index (PAI). Secondary outcome measures were proportion of teeth healed or improved in each group. Both groups exhibited equally favorable periapical healing at 12 months, with no statistically significant differences between groups.
authors.affiliation: Department of Endodontics, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, USA.
authors.forename: Vince A
authors.initials: VA
authors.lastname: Penesis
authors.forename: Patrick I
authors.initials: PI
authors.lastname: Fitzgerald
authors.forename: Mohamed I
authors.initials: MI
authors.lastname: Fayad
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Wenckus
authors.forename: Ellen A
authors.initials: EA
authors.lastname: BeGole
authors.forename: Bradford R
authors.initials: BR
authors.lastname: Johnson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001861:Bone Regeneration; D002126:Calcium Hydroxide; D002710:Chlorhexidine / Q000627:therapeutic use; D003790:Dental Pulp Necrosis / Q000628:therapy*; D003794:Dental Restoration, Temporary; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009819:Office Visits; D010485:Periapical Periodontitis / Q000628:therapy*; D010512:Periodontal Index; D011859:Radiography; D012387:Root Canal Filling Materials; D012390:Root Canal Therapy / Q000379:methods*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000890:Anti-Infective Agents; D012387:Root Canal Filling Materials; D002126:Calcium Hydroxide; D002710:Chlorhexidine