title: Cardiovascular therapy of neurosurgical patients.
abstract: The causes of postoperative cardiovascular disturbances in neurosurgical patients include direct cardiac neurogenic effects, clinical situations where brain tissue is underperfused, and hyperdynamic states. EKG and echographic abnormalities are common in subarachnoid hemorrhage where cardiac troponin I is the most useful predictor of cardiac risk after SAH. Neurogenic pulmonary edema is short lived and often resolves with resolution of the neurologic problem. In traumatic brain injury, where areas of ischemia co-exist with luxury perfusion, advanced hemodynamic monitoring and prevention of jugular venous desaturation best avoid secondary brain injury and achieve optimal neurologic outcome. Induced hypertension improves blood flow through vessels compromised by cerebral stenting, angioplasty, microcatheters, thrombolysis, carotid clamping, intracranial bypass and cerebral vasospasm. Hyperdynamic lesions include vascular breakthrough after elimination of cerebral arteriovenous malformations, but also emergence hypertension and hyperemia. Pharmacologic agents and adjunctive measures are effective in controlling both the systemic and the cerebral circulation.
authors.affiliation: Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of General Anesthesiology, Cleveland Clinic, 9500 Euclid Avenue/E31, Cleveland, Ohio 44195, USA. schubea@ccf.org
authors.forename: Armin
authors.initials: A
authors.lastname: Schubert
mesh_terms: D001794:Blood Pressure; D001930:Brain Injuries / Q000503:physiopathology / Q000601:surgery; D002318:Cardiovascular Diseases / Q000209:etiology / Q000628:therapy*; D002560:Cerebrovascular Circulation; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000628:therapy; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D011182:Postoperative Care; D011654:Pulmonary Edema / Q000209:etiology / Q000628:therapy; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology / Q000601:surgery