Meta-analysis of tacrolimus ointment for atopic dermatitis in pediatric patients.
We evaluated the efficacy and safety of tacrolimus ointment in the treatment of the pediatric patients with atopic dermatitis. Tacrolimus ointment therapy resulted in the remission of atopic dermatitis, this effect of tacrolimus ointment strengths 0.03% and 0.1% were better than those of 1% hydrocortisone acetate and 1% pimecrolimus. Difference between the 0.03% tacrolimus group and the 0.1% tacrolimus group was not statistically significant.
Yan
Jun
J
School of Pharmacy, Shandong University, and Jinan City Hospital for Skin Diseases Prevention and Treatment, Jinan, China.
Chen
Sheng-Li
SL
Wang
Xiao-Lin
XL
Zhou
Wen
W
Wang
Feng-shan
FS
D000287:Administration, Topical; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000188:drug therapy*; D019317:Evidence-Based Medicine; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009824:Ointments / Q000627:therapeutic use; D010372:Pediatrics / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D016559:Tacrolimus / Q000627:therapeutic use*; D016896:Treatment Outcome
D009824:Ointments; D016559:Tacrolimus