[Severe thrombocytosis and leukocytosis associated with iron deficiency anaemia: a case-report].
Reactive thrombocytosis (secondary thrombocytosis) is frequent and typically moderate. We report a case of extreme thrombocytosis and leukocytosis secondary to an iron deficiency anemia. A 21-year-old woman is admitted in emergency department for acute headache. Biological assessment reveals a severe microcytic anaemia (5.4 g/dL) with thrombocytosis (2500 giga/L) and leukocytosis (35 giga/L) leading to multiple diagnosis hypotheses. Finally, biological evaluation concludes to a diagnosis of iron deficiency anaemia related to insufficient oral intake and menorrhagia. Reactive hyperleukocytosis and thrombocytosis rapidly resolved with iron supplementation. This case is a reminder that iron deficiency-related thrombocytosis can sometimes be severe. However, the associated reactive leukocytosis is quite exceptional.
Bernard
F
F
Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France.
Baccini
V
V
Bagneres
D
D
Rossi
P
P
Demoux
A L
AL
Bonin-Guillaume
S
S
Frances
Y
Y
Granel
B
B
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000150:complications*; D005260:Female; D006801:Humans; D007964:Leukocytosis / Q000209:etiology*; D012720:Severity of Illness Index; D013922:Thrombocytosis / Q000209:etiology*