From furans to anilines: toward one-pot two-step amination/diels-alder sequences.
Selective metal-free amination and Diels-Alder reactions are described in the furan series, leading to polysubstituted anilines or to stable oxabicyclic adducts in high yield. Interestingly, anilines are conveniently prepared through a novel one-pot, two-step amination/Diels-Alder procedure from commercially available 5-bromo-2-furaldehyde.
Medimagh
Raouf
R
Institut Lavoisier de Versailles (ILV) UMR CNRS 8180, Université de Versailles-Saint-Quentin-en-Yvelines, 45 Avenue des Etats-Unis, 78 035 Versailles, Cedex, France.
Marque
Sylvain
S
Prim
Damien
D
Chatti
Saber
S
Zarrouk
Hédi
H
D000586:Amination; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D005662:Furaldehyde / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods
D000814:Aniline Compounds; D005663:Furans; D005662:Furaldehyde