title: Prevalence of poor performance status in lung cancer patients: implications for research.
abstract: BACKGROUND
  Performance status (PS) is a standard functional classification in oncology research and practice. However, despite its widespread use, little is known about the prevalence of poor PS in lung cancer patients, in relation to other cancers, based on the assessments of health care providers and patients.
  
  
  METHODS
  Data from two quality of life studies were pooled for analysis. Analyses were performed on the subset of patients with lung cancer (n = 503) from the entire population of cancer patients (n = 2885). The prevalence of poor PS (defined as PS = 2-4 on a 0-4 scale) was determined for lung cancer patients.
  
  
  RESULTS
  Prevalence of poor PS among lung cancer patients was 34% when estimated by providers and 48% when estimated by patients themselves. Agreement between providers and patients was only fair (weighted [kappa] = 0.41). For both advanced and early stage disease, lung cancer patients were at the highest risk for poor PS compared with other common cancers.
  
  
  CONCLUSIONS
  The prevalence of poor PS is quite high in lung cancer patients. Providers tend to underestimate poor PS. Specific clinical trials and treatment guidelines for this patient population are urgently needed.
authors.affiliation: Thoracic Oncology Program, Mount Sinai Cancer Center, Miami Beach, Florida 33140, USA. Rlilenba@msmc.com
authors.forename: Rogerio C
authors.initials: RC
authors.lastname: Lilenbaum
authors.forename: John
authors.initials: J
authors.lastname: Cashy
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Hensing
authors.forename: Susan
authors.initials: S
authors.lastname: Young
authors.forename: David
authors.initials: D
authors.lastname: Cella
mesh_terms: D005260:Female; D006304:Health Status; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology / Q000473:pathology; D015995:Prevalence; D011446:Prospective Studies; D011647:Puerto Rico / Q000453:epidemiology; D011788:Quality of Life; D012306:Risk; D012720:Severity of Illness Index; D014481:United States / Q000453:epidemiology