title: [Application of brilliant x-rays in mammography. Development and perspectives of phase contrast techniques].
abstract: The early and reliable detection of breast cancer is often difficult with conventional mammography, especially within dense breast parenchyma. An alternative approach using x-rays are phase-sensitive imaging techniques, which are able to visualize the borders of tissues with different refraction indices with very high contrast. These phase contrast imaging techniques can generate projection images with much less glandular dose than conventional mammography. Even the acquisition of phase contrast CT data sets with an acceptable exposure dose is possible. As brilliant x-ray beams are required for phase contrast imaging, which up to now were only available at synchrotron facilities, these methods were restricted to only a few laboratories. However, with the advent of newly developed high intensity lasers which are also able to produce such radiation, a widespread and affordable use of this technique seems realistic. The further development of phase contrast imaging is funded by the excellence cluster MAP of the Munich universities.
authors.affiliation: Institut für Klinische Radiologie, Klinikum Ludwig-Maximilians-Universität München, München. tanja.schneider@med.uni-muenchen.de
authors.forename: T
authors.initials: T
authors.lastname: Schneider
authors.forename: P
authors.initials: P
authors.lastname: Coan
authors.forename: D
authors.initials: D
authors.lastname: Habs
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D015502:Absorptiometry, Photon / Q000639:trends*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D005544:Forecasting; D006801:Humans; D008327:Mammography / Q000639:trends*; D008403:Mass Screening / Q000639:trends*; D011856:Radiographic Image Enhancement / Q000379:methods* / Q000639:trends*; D014961:X-Ray Diffraction / Q000639:trends*; D014965:X-Rays