title: Prospective analysis of lipid profiles in persons with a spinal cord injury during and 1 year after inpatient rehabilitation.
abstract: OBJECTIVE
  To investigate the course of lipid profiles during and 1 year after inpatient rehabilitation of persons with spinal cord injury, and to determine which personal, lesion, and lifestyle characteristics influence the changes in lipid profiles over time and among subjects.
  
  
  METHODS
  Multilevel regression analysis of measurement points during and after rehabilitation.
  
  
  METHODS
  Eight rehabilitation centers in The Netherlands.
  
  
  METHODS
  People with complete and incomplete paraplegia and tetraplegia (N=180).
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG), and the TC/HDL ratio.
  
  
  RESULTS
  We found a significant decrease in TG and TC/HDL during inpatient rehabilitation and a significant increase in HDL during and after inpatient rehabilitation. TC and LDL, however, showed unfavorable increases after clinical discharge. The changes in HDL and LDL over time differed between lesion groups. An increase in the body mass index (BMI) led to an unfavorable change in all lipid profiles. Older participants showed higher TC, LDL, and HDL concentrations. Women and participants who consumed some alcohol, or who were more active 1 year after discharge, had more favorable HDL levels.
  
  
  CONCLUSIONS
  Lipid profiles improved during inpatient rehabilitation but deteriorated somewhat after clinical discharge. Controlling one's BMI seems important in diminishing the risk for unfavorable lipid profiles.
authors.affiliation: Rehabilitation Center Amsterdam, Amsterdam, The Netherlands. s.de.groot@fbw.vu.nl
authors.forename: Sonja
authors.initials: S
authors.lastname: de Groot
authors.forename: Annet J
authors.initials: AJ
authors.lastname: Dallmeijer
authors.forename: Marcel W
authors.initials: MW
authors.lastname: Post
authors.forename: Edmond L
authors.initials: EL
authors.lastname: Angenot
authors.forename: Rita J
authors.initials: RJ
authors.lastname: van den Berg-Emons
authors.forename: Luc H
authors.initials: LH
authors.lastname: van der Woude
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D015331:Cohort Studies; D006801:Humans; D015601:Injury Severity Score; D007297:Inpatients; D008019:Life Style; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D015999:Multivariate Analysis; D010264:Paraplegia / Q000097:blood / Q000534:rehabilitation; D026741:Physical Therapy Modalities; D011237:Predictive Value of Tests; D011336:Probability; D011446:Prospective Studies; D011782:Quadriplegia / Q000097:blood / Q000534:rehabilitation; D012044:Regression Analysis; D012047:Rehabilitation Centers; D013119:Spinal Cord Injuries / Q000097:blood* / Q000175:diagnosis* / Q000534:rehabilitation*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D008076:Cholesterol, HDL; D008055:Lipids