title: Anthelmintic activities of three medicinal plants from Nigeria.
abstract: Aqueous extracts of the leaf, stem bark and root bark from Canna bidentata, Spondias mombin and Commiphora africana were examined for anthelmintic activity against earthworm. All the extracts demonstrated a concentration-dependent activity at tested concentrations of 10-80 mg/ml. Higher activities were observed at the higher concentrations, 40-80 mg/ml for all the plant extracts. C. bidentata with a paralysis time of 3-5 min and death time of 5-18 min at these concentrations for the stem bark, and S. mombin which exhibited comparatively higher efficacy (34-44 min paralysis time and 105 min death time for the leaf) at lower concentrations of 10-20 mg/ml were adjudged the outstanding anthelmintics of plant origin accordingly.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria. adegbolade@yahoo.com
authors.forename: A A
authors.initials: AA
authors.lastname: Gbolade
authors.forename: A A
authors.initials: AA
authors.lastname: Adeyemi
mesh_terms: D027926:Anacardiaceae; D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D029744:Commiphora; D006801:Humans; D019684:Magnoliopsida; D016488:Medicine, African Traditional; D009549:Nigeria; D009835:Oligochaeta / Q000187:drug effects*; D021261:Parasitic Sensitivity Tests; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D018517:Plant Roots; D010946:Plants, Medicinal
chemical_list: D000871:Anthelmintics; D010936:Plant Extracts