[Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction].
OBJECTIVE
Optimize the technic condition of Duzhong Jiangya prescription with Semi-bionic Extraction.


METHODS
Using homogeneous design, under the same materials granularity, decoction temperature, consumption of water, filtration, concentration, and taking aucubin, hydrochloric acid stachydrine, maloicacid, baicalin, ethanol extract, dry extract as the indexes, the results were comprehensive considered to optimize the semi-bionic extraction condtions.


RESULTS
The optimized SBE extraction conditions are the following: pH values of the water for the thrice extraction is 5.845 3, 7.496 1, 8.011 7, and the total extraction time is 3.418 0 h.


CONCLUSIONS
Considering the fact of manufacture, the SBE extraction conditions are the following: pH values of the water for the thrice extraction is 6.0, 7.5, 8.0, and the thrice extraction time is 1.5, 1.0, 1.0 h.
Zhao
Xue-Mei
XM
Shangdong Provincial Hospital, Jinan 250021, China. zxm_vip@yahoo.com.cn
Sun
Xiu-Mei
XM
Zhang
Zhao-Wang
ZW
Hui
Jian-Guo
JG
D000959:Antihypertensive Agents / Q000737:chemistry / Q000302:isolation & purification; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D031283:Eucommiaceae / Q000737:chemistry*; D005419:Flavonoids / Q000032:analysis; D005960:Glucosides / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D057888:Iridoid Glucosides; D039823:Iridoids / Q000032:analysis; D031332:Leonurus / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives / Q000032:analysis; D031347:Prunella / Q000737:chemistry; D031364:Scutellaria baicalensis / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors; D014315:Triterpenes / Q000032:analysis; D032070:Uncaria / Q000737:chemistry; D000097245:Ursolic Acid
D000959:Antihypertensive Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D005960:Glucosides; D057888:Iridoid Glucosides; D039823:Iridoids; D011392:Proline; D014315:Triterpenes; D000097245:Ursolic Acid; C006650:aucubin; C038044:baicalin; C003342:stachydrine