Groucho/Tup1 family co-repressors in plant development.
Transcription repression is emerging as a key regulatory mechanism underlying cell fate specification and body patterning in both animals and plants. In animals and fungi, the Groucho (Gro)/Tup1 family co-repressors generate the repressed chromatin state in genetic loci that control major developmental decisions ranging from dorsal-ventral patterning to eye development. In higher plants, information about the Gro/Tup1 co-repressors is beginning to emerge. Several recent publications have revealed both conserved and unique structural and mechanistic features of plant Gro/Tup1 co-repressors, including LEUNIG (LUG), TOPLESS (TPL) and WUSCHEL-INTERACTING PROTEINS (WSIPs). These co-repressors regulate key developmental processes in floral organ identity specification, embryo apical-basal fate determination, and stem cell maintenance at the shoot apex.
Liu
Zhongchi
Z
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. zhongchil@gmail.com
Karmarkar
Vidyadhar
V
D000818:Animals; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D008954:Models, Biological; D010802:Phylogeny; D063245:Plant Development; D010940:Plant Proteins / Q000145:classification / Q000235:genetics / Q000502:physiology*; D010944:Plants / Q000196:embryology / Q000235:genetics; D012097:Repressor Proteins / Q000145:classification / Q000235:genetics / Q000502:physiology*
D010940:Plant Proteins; D012097:Repressor Proteins