Quantized current blockade and hydrodynamic correlations in biopolymer translocation through nanopores: evidence from multiscale simulations.
We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent using an innovative multiscale methodology that treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding up the translocation process.
Bernaschi
Massimo
M
Istituto Applicazioni Calcolo, CNR, Viale del Policlinico 137, 00161 Roma, Italy.
Melchionna
Simone
S
Succi
Sauro
S
Fyta
Maria
M
Kaxiras
Efthimios
E