New constructions of one- and two-stage pooling designs.
The study of gene functions requires a DNA library of high quality, such a library is obtained from a large mount of testing and screening. Pooling design is a very helpful tool for reducing the number of tests for DNA library screening. In this paper, we present new one- and two-stage pooling designs, together with new probabilistic pooling designs. The approach in this paper works for both error-free and error-tolerance scenarios.
Cheng
Yongxi
Y
Institute for Theoretical Computer Science, Tsinghua University, Beijing, China. cyx@mails.tsinghua.edu.cn
Du
Ding-Zhu
DZ
D000465:Algorithms; D019295:Computational Biology; D015723:Gene Library; D008433:Mathematics; D008962:Models, Theoretical; D017422:Sequence Analysis, DNA