title: Serum alpha-1-antitriypsin levels in patients with pseudoexfolative syndrome.
abstract: OBJECTIVE
  To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX.
  
  
  METHODS
  Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry.
  
  
  RESULTS
  The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001).
  
  
  CONCLUSIONS
  Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
authors.affiliation: Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. tongabay@superonline.com
authors.forename: Tongabay
authors.initials: T
authors.lastname: Cumurcu
authors.forename: Huseyin
authors.initials: H
authors.lastname: Ozyurt
authors.forename: Helin Deniz
authors.initials: HD
authors.lastname: Demir
authors.forename: Huseyin
authors.initials: H
authors.lastname: Yardim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017889:Exfoliation Syndrome / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D000515:alpha 1-Antitrypsin / Q000097:blood*
chemical_list: C043392:SERPINA1 protein, human; D000515:alpha 1-Antitrypsin