Diagnostic efficacy of bone scintigraphy, magnetic resonance imaging, and positron emission tomography in bone metastases of myxoid liposarcoma.
Myxoid liposarcomas (MLS) have a tendency to metastasize to unusual sites. We report an unusual case of bone metastases not detected by bone scan and neither by fluorodeoxyglucose positron emission tomography (PET-FDG) and successfully identified with magnetic resonance imaging (MRI) in a patient with metachronic MLS. Histopathological examination of the primary tumor evidenced a tumor with unfavorable prognostic markers, and the biopsy of an iliac bone lesion confirmed the diagnosis of metastatic disease. On histological grounds, the tumor showed features of a more differentiated neoplasm without foci of round cells or necrosis in the latter. MRI allowed the identification of disseminated disease compared to computed tomography (CT) and PET scans. Thus, because of the heterogeneous histological features of MLS and the biological behavior of the disease, a combined approach of FDGPET-CT and MRI, may allow a more accurate staging of soft tissue sarcomas.
Conill
Carlos
C
Department of Radiation Oncology, Musculoskeletal Oncology Unit, Institute of Hematology and Oncology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. cconill@clinic.ub.es
Setoain
Xavier
X
Colomo
Luis
L
Palacín
Antonio
A
Combalia-Aleu
Andreu
A
Pomés
Jaime
J
Marruecos
Jordi
J
Vargas
Mauricio
M
Maurel
Joan
J
D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D018208:Liposarcoma, Myxoid / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D012983:Soft Tissue Neoplasms / Q000473:pathology*
D019788:Fluorodeoxyglucose F18