Consumption of fruit and vegetables and risk of lung cancer: a case-control study in Galicia, Spain.
OBJECTIVE
We analyzed the effect of fruit and vegetable intake on lung cancer risk in a population in northwest Spain.


METHODS
We analyzed data from a hospital-based case-control study including 295 histologically confirmed cases and 322 controls. Controls were patients attending the hospital for minor surgery. There was a minimum age limit of 35 y and sampling was carried out on a sex-frequency basis.


RESULTS
After adjustment for sex, age, tobacco use, and occupation, no protective effect of overall consumption of fruit was present (odds ratio 1.49, 95% confidence interval 0.81-2.73). Green leafy vegetables conferred a protective effect (odds ratio 0.50, 95% confidence interval 0.30-0.83).


CONCLUSIONS
These findings indicate that green leafy vegetables, rather than fruit, might have a genuine protective effect against lung cancer.
Dosil-Díaz
Olga
O
Galician Public Foundation for Health Emergencies-061, Santiago de Compostela, Spain.
Ruano-Ravina
Alberto
A
Gestal-Otero
Juan J
JJ
Barros-Dios
Juan M
JM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D016001:Confidence Intervals; D005260:Female; D005638:Fruit; D006801:Humans; D016015:Logistic Models; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012907:Smoking; D013030:Spain / Q000453:epidemiology; D014675:Vegetables