title: Integrating sensitive quantification of hepatic metabolic functions by capillary electrophoresis with laser-induced fluorescence detection.
abstract: We report the establishment of capillary electrophoresis with laser-induced fluorescence (CE-LIF) detection as a common analytical platform for sensitive quantification of both phase I and II metabolism in various hepatic in vitro models.
authors.affiliation: Institute of Biotechnology and Nanotechnology, A*STAR, The Nanos, #04-01, 31 Biopolis Way, Singapore 138669, Singapore.
authors.forename: Yi-Chin
authors.initials: YC
authors.lastname: Toh
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Yuet Mei
authors.initials: YM
authors.lastname: Khong
authors.forename: Yanan
authors.initials: Y
authors.lastname: Du
authors.forename: Wanxin
authors.initials: W
authors.lastname: Sun
authors.forename: Hanry
authors.initials: H
authors.lastname: Yu
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques; D019075:Electrophoresis, Capillary / Q000379:methods*; D005456:Fluorescent Dyes; D006801:Humans; D007834:Lasers; D008099:Liver / Q000737:chemistry / Q000378:metabolism*; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes