Temperature-controlled synthesis of substituted pyridine derivatives via the [5C + 1N] annulation of 1,1-bisalkylthio-1,4-pentanedienes and ammonium acetate.
A novel temperature-controlled one-pot synthesis of substituted pyridine derivatives via [5C + 1N] annulation of 1,1-bisalkylthio-1,4-pentanedienes and ammonium acetate is developed, and possible mechanisms leading to the divergent formation of the two types of pyridines are discussed.
Hu
Jianglei
J
Department of Chemistry, Northeast Normal University, Changchun 130024, China.
Zhang
Qian
Q
Yuan
Hongjuan
H
Liu
Qun
Q
D000085:Acetates / Q000737:chemistry*; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D010420:Pentanes / Q000737:chemistry*; D011090:Polyenes / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis*; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013696:Temperature
D000085:Acetates; D010420:Pentanes; D011090:Polyenes; D011725:Pyridines; D013438:Sulfhydryl Compounds; C018824:ammonium acetate