Advances in FIV vaccine technology.
Advances in vaccine technology are occurring in the molecular techniques used to develop vaccines and in the assessment of vaccine efficacy, allowing more complete characterization of vaccine-induced immunity correlating to protection. FIV vaccine development has closely mirrored and occasionally surpassed the development of HIV-1 vaccine, leading to first licensed technology. This review will discuss technological advances in vaccine designs, challenge infection assessment, and characterization of vaccine immunity in the context of the protection detected with prototype and commercial dual-subtype FIV vaccines and in relation to HIV-1.
Uhl
Elizabeth W
EW
Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA 30602-7388, USA.
Martin
Marcus
M
Coleman
James K
JK
Yamamoto
Janet K
JK
D000818:Animals; D002415:Cats; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000517:prevention & control / Q000821:virology; D007111:Immunity, Cellular / Q000276:immunology; D016089:Immunodeficiency Virus, Feline / Q000276:immunology*; D022223:Vaccines, Subunit / Q000737:chemistry / Q000276:immunology / Q000494:pharmacology; D014765:Viral Vaccines / Q000737:chemistry / Q000276:immunology* / Q000494:pharmacology
D022223:Vaccines, Subunit; D014765:Viral Vaccines