title: Clinical utility of hybrid SPECT-CT in endocrine neoplasia.
abstract: OBJECTIVE
  Imaging of endocrine neoplasms often involves a combination of anatomic and functional techniques including sonography, CT, MRI, and scintigraphy. Recent technologic advances have enabled hybrid imaging using SPECT-CT, which combines anatomic and functional techniques to allow accurate localization of tumors, increased detection of recurrent and metastatic disease, and exclusion of physiologic uptake.
  
  
  CONCLUSIONS
  SPECT-CT provides improved specificity and diagnostic confidence helping to guide conventional management and assess suitability for targeted radionuclide therapy.
authors.affiliation: Department of Radiology, St. James' University Hospital, Beckett St., Leeds LS9 7TF, United Kingdom. chirag.patel@leedsth.nhs.uk
authors.forename: Chirag N
authors.initials: CN
authors.lastname: Patel
authors.forename: Fahmid U
authors.initials: FU
authors.lastname: Chowdhury
authors.forename: Andrew F
authors.initials: AF
authors.lastname: Scarsbrook
mesh_terms: D004701:Endocrine Gland Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D009377:Multiple Endocrine Neoplasia; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed