title: [Risk factors for death from severe malaria in children at the Charles de Gaulle pediatric hospital of Ouagadougou (Burkina Faso)].
abstract: To determine the risk factors for death from severe malaria in children in Burkina Faso, we conducted a retrospective case-control study covering a period of 24 months from January 2004 through December 2005, at the Charles de Gaulle Pediatric Hospital in Ouagadougou. Cases (n=72) were defined as all children hospitalized for and dying of confirmed severe malaria. The control subjects (n=72), matched for age, sex and date of hospitalization; were children hospitalized for confirmed severe malaria who were discharged after recovery. Risk factors assessed included: place of residence, socioeconomic level, self-medication, promptness of hospitalization, nutritional status, temperature and parasitemia. Case and control children were compared with pairwise tests. Low socioeconomic level (OR=5.4), late care (OR=15.5), poor nutritional status (OR=7.9) and a parasitemia greater than or equal to 5% (OR=2.8) were associated with a significant increase in the risk of death. In contrast, the malaria deaths were not associated with place of residence (OR=0.5), self-medication (OR=1) or fever of 41 degrees C or higher (OR=1.1). These results show the need for more health education to encourage early care-seeking in the event of fever, community-based interventions, and strengthening of the technical support centers for health facilities, as part of a national poverty reduction program.
authors.affiliation: Unité de formation et de recherche en sciences de la santé (UFR/SDS), Université de Ouagadougou, Service de pédiatrie médicale du CHUP-CDG, BP 1198 BP 01, Ouagadougou 01, Burkina Faso. kouetafla@yahoo.com
authors.forename: Fla
authors.initials: F
authors.lastname: Kouéta
authors.forename: Lassina
authors.initials: L
authors.lastname: Dao
authors.forename: Diarra
authors.initials: D
authors.lastname: Yé
authors.forename: Alice
authors.initials: A
authors.lastname: Zoungrana
authors.forename: Aïssata
authors.initials: A
authors.lastname: Kaboré
authors.forename: Alphonse
authors.initials: A
authors.lastname: Sawadogo
mesh_terms: D000293:Adolescent; D002050:Burkina Faso / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D005260:Female; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000453:epidemiology / Q000401:mortality*; D008297:Male; D015999:Multivariate Analysis; D009752:Nutritional Status; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors