title: Look who's talking: nuclear receptors in the liver and gastrointestinal tract.
abstract: The Nuclear Receptors in Liver and Digestive Diseases research workshop was held in Rockville, Maryland, on November 7 and 8, 2007, under the auspices of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. Over 130 researchers from around the world gathered to assess the pathophysiology of nuclear receptors in the liver and gastrointestinal tract and to explore their potential use as therapeutic targets. This review covers some of the highlights of the meeting, including important areas of future investigation.
authors.affiliation: Howard Hughes Medical Institute, Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Downes
authors.forename: Christopher
authors.initials: C
authors.lastname: Liddle
mesh_terms: D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D002779:Cholestasis / Q000188:drug therapy / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D005215:Fasting / Q000378:metabolism; D005234:Fatty Liver / Q000188:drug therapy / Q000378:metabolism; D005346:Fibroblast Growth Factors / Q000378:metabolism; D005765:Gastrointestinal Agents / Q000494:pharmacology / Q000627:therapeutic use; D041981:Gastrointestinal Tract / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D056953:Nuclear Receptor Subfamily 1, Group D, Member 1; D019518:Postprandial Period; D018160:Receptors, Cytoplasmic and Nuclear / Q000187:drug effects / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D001647:Bile Acids and Salts; D004268:DNA-Binding Proteins; D005765:Gastrointestinal Agents; C064353:NR1D1 protein, human; D056953:Nuclear Receptor Subfamily 1, Group D, Member 1; D018160:Receptors, Cytoplasmic and Nuclear; D005346:Fibroblast Growth Factors; D002784:Cholesterol