Antimalarial drugs - what is in use and what is in the pipeline.
Malaria continues to be a potentially fatal threat to almost half of the world's population. In light of this threat, the armory to fight this disease is rather limited. Resistance against the most common and affordable antimalarials is widespread. Only few new drugs are in clinical development, most of them belong to long used classes of antimalarial drugs. This review will concisely cover the drugs which are currently in use, and describe the drug candidates which are in clinical evaluation.
Schlitzer
Martin
M
Philipps-Universität, Institut für Pharmazeutische Chemie, Marburg, Germany. martin.schlitzer@staff.uni-marburg.de
D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D015195:Drug Design; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000188:drug therapy*
D000962:Antimalarials; D004338:Drug Combinations