Rapid and efficient entry to vinyl silanes from aldehydes employing a novel metalation-Peterson sequence.
Bis(trimethylsilyl)chloromethane undergoes a rapid and selective metalation with s-BuLi, yielding the nucleophilic bis(trimethylsilyl)methyl anion and providing a straightforward general entry to vinyl silanes from aromatic, aliphatic and vinyl aldehydes.
McNulty
James
J
Department of Chemistry, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada. jmcnult@mcmaster.ca
Das
Priyabrata
P