title: The Cutaneous Lupus Erythematosus Disease Activity and Severity Index: expansion for rheumatology and dermatology.
abstract: OBJECTIVE
  To evaluate the validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) for use by rheumatologists via reliability testing, and to extend the validation for dermatologists.
  
  
  METHODS
  Fourteen subjects with cutaneous lupus erythematosus (CLE; n = 10), a mimicker skin disease only (a cutaneous lesion that may appear clinically similar to CLE; n = 1), or both (n = 3) were rated with the CLASI by academic-based dermatologists (n = 5) and rheumatologists (n = 5).
  
  
  RESULTS
  The dermatology intraclass correlation coefficient (ICC) was 0.92 for activity and 0.82 for damage; for rheumatology the ICC was 0.83 for activity and 0.86 for damage. For intrarater reliability, the dermatology Spearman's rho was 0.94 for activity and 0.97 for damage; for rheumatology the Spearman's rho was 0.91 for activity and 0.99 for damage.
  
  
  CONCLUSIONS
  Our data confirm the reliability of the CLASI when used by dermatologists and support the CLASI as a reliable instrument for use by rheumatologists.
authors.affiliation: University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Krathen
authors.forename: J
authors.initials: J
authors.lastname: Dunham
authors.forename: E
authors.initials: E
authors.lastname: Gaines
authors.forename: J
authors.initials: J
authors.lastname: Junkins-Hopkins
authors.forename: E
authors.initials: E
authors.lastname: Kim
authors.forename: S L
authors.initials: SL
authors.lastname: Kolasinski
authors.forename: C
authors.initials: C
authors.lastname: Kovarik
authors.forename: J
authors.initials: J
authors.lastname: Kwan-Morley
authors.forename: J
authors.initials: J
authors.lastname: Okawa
authors.forename: K
authors.initials: K
authors.lastname: Propert
authors.forename: N
authors.initials: N
authors.lastname: Rogers
authors.forename: M
authors.initials: M
authors.lastname: Rose
authors.forename: P
authors.initials: P
authors.lastname: Thomas
authors.forename: A B
authors.initials: AB
authors.lastname: Troxel
authors.forename: A
authors.initials: A
authors.lastname: Van Voorhees
authors.forename: J Von
authors.initials: JV
authors.lastname: Feldt
authors.forename: A L
authors.initials: AL
authors.lastname: Weber
authors.forename: V P
authors.initials: VP
authors.lastname: Werth
mesh_terms: D000293:Adolescent; D000328:Adult; D003880:Dermatology; D003882:Dermatomyositis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012219:Rheumatology; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index