title: [Mast cells and innervation of the wall of the hyperactive urinary bladder].
abstract: Anterior urinary bladder wall biopsy specimens were examined in 24 males and 4 females, aged 52 to 76 years, who had been suffering from the hyperactive urinary bladder for 1-10 years. Increases in the number and activity of interstitial mast cells and their degranulation and the symptoms of chronic immune inflammation were revealed. Neuromuscular spastic dysfunction of the detrusor is considered to result from the activation of mast cells.
authors.forename: O B
authors.initials: OB
authors.lastname: Loran
authors.forename: V N
authors.initials: VN
authors.lastname: Shvalev
authors.forename: S A
authors.initials: SA
authors.lastname: Pisarev
authors.forename: N V
authors.initials: NV
authors.lastname: Kleĭmenova
authors.forename: V S
authors.initials: VS
authors.lastname: Sukhorukov
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000502:physiology* / Q000648:ultrastructure; D008875:Middle Aged; D001743:Urinary Bladder / Q000294:innervation* / Q000473:pathology; D053201:Urinary Bladder, Overactive / Q000473:pathology*