[Recent progresses in studies on bioactive lignans from plants].
Lignans are widely existed in natural world with a variety of structures and bioactivities, including anti-tumor, antiinflammatory, anti-viral and hepatoprotective properties. Along with the development of new techniques in phytochemistry and application of advanced drug screening methods, a variety of lignans have been identified and their bioactivities revealed. In this review, we summarized the activities of six different types of lignans, including arylnaphthalene, dibenzylbutyrolactone, tetrahydrofuran, dibenzylbutane, dibenzocyclooctadiene and neolignan, in order to provide an updated overview of this research field.
Zhang
Guo-Liang
GL
National Center for Drug Screening, Shanghai 201203, China]
Li
Na
N
Lin
Li-Lin
LL
Wang
Ming-Wei
MW
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D034242:Cyclooctanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D000998:Antiviral Agents; D034242:Cyclooctanes; D005663:Furans; D017705:Lignans; C511097:dibenzocyclooctadiene; C018674:tetrahydrofuran