title: TMJ osteoarthritis/osteoarthrosis and immune system factors in a Japanese sample.
abstract: OBJECTIVE
  To determine whether there is an association between temporomandibular joint (TMJ) osteoarthritis/osteoarthrosis (OA) and immune system factors in a Japanese sample.
  
  
  METHODS
  The records of 41 subjects (7 men, aged 22.0 +/- 3.8 years; 34 women, aged 24.8 +/- 6.3 years) and 41 pair-matched controls (7 men, aged 22.1 +/- 2.3 years; 34 women, aged 24.8 +/- 6.4 years) based on age and gender were reviewed. Information on medical history included local or systemic diseases, details on medication type and use, and the presence of allergies and asthma. Dental history questions referred to details regarding past oral injuries. The validity of the hypothesis, defining allergies and asthma as risk factors in OA, was tested by using a logistic regression analysis.
  
  
  RESULTS
  The incidence of allergy was significantly higher in the TMJ OA (P = .008), with a mean odds ratio of 4.125 and a 95% confidence interval of 1.446-11.769.
  
  
  CONCLUSIONS
  These results suggest that allergy may be a risk factor in association with TMJ OA in this Japanese sample.
authors.affiliation: Department of Orthodontics, Kyushu University, Fukuoka, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Nishioka
authors.forename: Hideki
authors.initials: H
authors.lastname: Ioi
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Matsumoto
authors.forename: Tazuko K
authors.initials: TK
authors.lastname: Goto
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Nakata
authors.forename: Akihiko
authors.initials: A
authors.lastname: Nakasima
authors.forename: Amy L
authors.initials: AL
authors.lastname: Counts
authors.forename: Ze'ev
authors.initials: Z
authors.lastname: Davidovitch
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis; D016022:Case-Control Studies; D003876:Dermatitis, Atopic / Q000175:diagnosis; D003877:Dermatitis, Contact / Q000175:diagnosis; D004194:Disease; D004358:Drug Therapy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis; D007564:Japan; D008297:Male; D008487:Medical History Taking; D009055:Mouth / Q000293:injuries; D010003:Osteoarthritis / Q000276:immunology*; D011862:Radiography, Panoramic; D016059:Range of Motion, Articular / Q000502:physiology; D012130:Respiratory Hypersensitivity / Q000175:diagnosis; D012189:Retrospective Studies; D012307:Risk Factors; D013705:Temporomandibular Joint Disorders / Q000276:immunology*