title: Photoselective potassium titanyl phosphate (KTP) laser vaporization versus transurethral resection of the prostate for prostates larger than 70 mL: a short-term prospective randomized trial.
abstract: OBJECTIVE
  To compare the short term outcomes of photoselective vaporization (PVP) and transurethral resection of the prostate (TURP) for glands larger than 70 mL in a prospective randomized trial.
  
  
  METHODS
  Seventy-six consecutive patients with enlarged prostatic adenomas of 70 to 100 mL were randomly assigned for surgical treatment with TURP (n = 37) or PVP (n = 39). International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF-5) scores, maximum flow rates (Qmax), postvoid urine residues (PVR), and transrectal ultrasound (TRUS) volumes were recorded. Operative data, complications, catheter removal, and hospitalization periods were also recorded. Patients were reassessed at 3 and 6 months.
  
  
  RESULTS
  Baseline characteristics of both groups were similar. Mean preoperative TRUS volume was 88 +/- 9.2 mL in the TURP group and 86.1 +/- 8.8 mL in the PVP group. The procedure was significantly shorter for the TURP group (51 +/- 17.2 minutes versus 87 +/- 18.3 minutes, P <0.05), catheter removal (3.9 +/- 1.2 days and 1.7 +/- 0.8 days, P <0.05), and hospital stay (4.8 +/- 1.2 days versus 2 +/- 0.7 days, P <0.05) were shorter in the PVP group. A significant difference in IPSS, Qmax and PVR values was observed within the follow-up period in favor of the TURP. The percentage volume reduction was significantly higher in TURP group. Reoperation was necessary in 7 patients in PVP but none in TURP group.
  
  
  CONCLUSIONS
  Although PVP offers advantageous over TURP with regard to intraoperative and perioperative safety, early functional results of TURP are superior to PVP in patients with enlarged prostates larger than 70 mL.
authors.affiliation: Department of 2nd Urology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.
authors.forename: Kaya
authors.initials: K
authors.lastname: Horasanli
authors.forename: Mesrur Selcuk
authors.initials: MS
authors.lastname: Silay
authors.forename: Bulent
authors.initials: B
authors.lastname: Altay
authors.forename: Orhan
authors.initials: O
authors.lastname: Tanriverdi
authors.forename: Kemal
authors.initials: K
authors.lastname: Sarica
authors.forename: Cengiz
authors.initials: C
authors.lastname: Miroglu
mesh_terms: D000368:Aged; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000473:pathology* / Q000601:surgery*; D013997:Time Factors; D020728:Transurethral Resection of Prostate