title: Synthesis of carbamoyl azides from primary amines and carbon dioxide under mild conditions.
abstract: Treatment of amines under a carbon dioxide atmosphere with tetramethylphenylguanidine (PhTMG) and diphenylphosphoryl azide (DPPA) in acetonitrile below 0 degrees C provides carbamoyl azides in high to excellent yields. In addition, epimerization is not observed when optically pure alpha-amino esters are used as substrates.
authors.affiliation: Departamento de Química OrgAnica, Universidade de Vigo, E-36310 Vigo, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: García-Egido
authors.forename: Miryam
authors.initials: M
authors.lastname: Fernandez-Suarez
authors.forename: Luis
authors.initials: L
authors.lastname: Muñoz
mesh_terms: D000588:Amines / Q000737:chemistry*; D001386:Azides / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D015394:Molecular Structure; D013696:Temperature
chemical_list: D000588:Amines; D001386:Azides; D002245:Carbon Dioxide