title: Treatment of acne scars using the plasma skin regeneration (PSR) system.
abstract: OBJECTIVE
  Acne scarring is a common and difficult to treat condition. The plasma skin regeneration (PSR) system is a novel device that causes delayed ablation of the epidermis and controlled thermal modification to the underlying dermis. PSR has previously been shown to be a safe and effective treatment for facial rhytides and benign skin lesions. In this study, we investigated the safety and efficacy of single-treatment, high-energy, double-pass PSR for the treatment of acne scarring.
  
  
  METHODS
  Ten patients with acne scarring and Fitzpatrick skin types I-III were included in the study. All patients underwent a single PSR treatment with two high-energy passes (3.5-4.0 J). Treatments were performed in an outpatient clinic setting. Nine patients completed 6 months of follow-up. Improvement was determined by patient questionnaires and physician evaluation of digital photographs taken prior to treatment and at 3 and 6 months post-treatment.
  
  
  RESULTS
  On average, patients reported 34% improvement in their acne scarring at 3 months and 33% improvement at 6 months. Blinded physician ratings of patient photos demonstrated 19% improvement at 3 months and 34% at 6 months. Re-epithelialization was complete by 4-6 days after treatment, and no serious adverse events were encountered.
  
  
  CONCLUSIONS
  PSR appears to provide a safe and effective single treatment, minimal downtime alternative for the treatment of acne scarring. Additional studies are warranted to further demonstrate the safety and efficacy of this device.
authors.affiliation: Dermatology Department, Naval Medical Center San Diego, San Diego, California, USA.
authors.forename: Michele J
authors.initials: MJ
authors.lastname: Gonzalez
authors.forename: William H
authors.initials: WH
authors.lastname: Sturgill
authors.forename: E Victor
authors.initials: EV
authors.lastname: Ross
authors.forename: Nathan S
authors.initials: NS
authors.lastname: Uebelhoer
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000328:Adult; D002921:Cicatrix / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D017060:Patient Satisfaction; D010865:Pilot Projects; D013997:Time Factors; D016896:Treatment Outcome