title: Composition, and anti-inflammatory and antioxidant activities of the volatile oil from the fruit peel of Garcinia brasiliensis.
abstract: The composition of the volatile oil obtained by hydrodistillation from the fruit peel of Garcinia brasiliensis (Mart.) Planch. et Triana was determined by GC/MS. A total of 38 components were identified, including gamma-muurolene (10.3%), spathulenol (8.7%), delta-cadinene (8.3%), torreyol (8.0%), alpha-cadinol (7.0%), cadalene (6.3%), and gamma-cadinene (5.3%). Oxygenated sesquiterpenes (43%) were the main group of compounds. The anti-inflammatory activity of the volatile oil was evaluated through the rat-paw edema model induced by carrageenan. Inhibition of the inflammatory process was noticed 3 h after carrageenan administration. In addition, the volatile oil showed poor antioxidant activity.
authors.affiliation: Laboratório de Cristalografia, Departamento de Ciências Exatas, Universidade Federal de Alfenas - UNIFAL-MG, Rua Gabriel Monteiro da Silva, 714, Alfenas - MG, 37130-000, Brazil. felipetmartins@yahoo.com.br
authors.forename: Felipe T
authors.initials: FT
authors.lastname: Martins
authors.forename: Antônio C
authors.initials: AC
authors.lastname: Doriguetto
authors.forename: Thiago C
authors.initials: TC
authors.lastname: de Souza
authors.forename: Kamila R D
authors.initials: KR
authors.lastname: de Souza
authors.forename: Marcelo H
authors.initials: MH
authors.lastname: Dos Santos
authors.forename: Maria E C
authors.initials: ME
authors.lastname: Moreira
authors.forename: Luiz C A
authors.initials: LC
authors.lastname: Barbosa
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002351:Carrageenan / Q000008:administration & dosage; D004195:Disease Models, Animal; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D029760:Garcinia / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D051381:Rats; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D016166:Free Radical Scavengers; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; D002351:Carrageenan