title: [Cardiogenic shock after ingestion of amphetamines on a ground of Mycoplasma myocarditis].
abstract: Amphetamines are considered as narcotics in France. Their use induces modifications of the central nervous system and of the cardiovascular, respiratory and urinary systems by a sympathomimetic indirect effect. Here is reported the observation of a young woman who absorbed amphetamines causing a cardiogenic shock on a ground of acute myocarditis. The constitution of haemodynamic, respiratory and neurologic distresses lead to the endotracheal intubation of the patient. The haemodynamic status remaining shaky, despite the use of vasoactive drugs, a circulatory assistance by intra-aortic counter pulsation balloon was carried out. The initial echocardiography showed a left ventricular ejection fraction lower than 20%. Amphetamine's toxicity mechanisms still remain complicated; on cardiovascular plan, some cases of coronary artery spasm have been described. The coronarography, not accomplished immediately, was normal. Toxicological samples revealed an abnormally high amphetamines concentration. The severity of the cardiac attack was amplified by a Mycoplasma pneumoniae myocarditis. There was a positive evolution in eight days. Intoxication and infection can difficultly be dissociated in this case of cardiogenic shock.
authors.affiliation: Service de réanimation polyvalente chirurgicale, centre hospitalier de Grenoble, B.P. 217, 38043 Grenoble cedex 9, France. karineberger_2000@yahoo.fr
authors.forename: K
authors.initials: K
authors.lastname: Berger
authors.forename: M-C
authors.initials: MC
authors.lastname: Hérault
authors.forename: V
authors.initials: V
authors.lastname: Danel
authors.forename: F
authors.initials: F
authors.lastname: Vincent
authors.forename: C
authors.initials: C
authors.lastname: Jacquot
mesh_terms: D000328:Adult; D000662:Amphetamines / Q000097:blood / Q000506:poisoning* / Q000652:urine; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D009175:Mycoplasma Infections / Q000150:complications*; D012770:Shock, Cardiogenic / Q000139:chemically induced* / Q000150:complications; D016896:Treatment Outcome
chemical_list: D000662:Amphetamines