A near-infrared-fluorescence-quenched gold-nanoparticle imaging probe for in vivo drug screening and protease activity determination.
Lee
Seulki
S
Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791, Korea.
Cha
Eui-Joon
EJ
Park
Kyeongsoon
K
Lee
Seung-Young
SY
Hong
Jin-Ki
JK
Sun
In-Cheol
IC
Kim
Sang Yoon
SY
Choi
Kuiwon
K
Kwon
Ick Chan
IC
Kim
Kwangmeyung
K
Ahn
Cheol-Hee
CH
D000818:Animals; D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor / Q000295:instrumentation* / Q000379:methods*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D051379:Mice; D008819:Mice, Nude; D046529:Microscopy, Electron, Transmission; D010447:Peptide Hydrolases / Q000032:analysis / Q000378:metabolism*; D011480:Protease Inhibitors / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared
D000970:Antineoplastic Agents; D011480:Protease Inhibitors; D006046:Gold; D010447:Peptide Hydrolases