title: Unusual detritylation of tritylated tetrazole in Sartan molecules.
abstract: Tritylated tetrazole of 2a underwent unusual detritylation under basic reaction condition during the synthesis of methyl ether of olmesartan medoxomil 1. The unusual detritylation was found to be a common feature in the case of all tetrazole containing Sartan molecules (3-7).
authors.affiliation: Department of Process Chemistry, Advinus Therapeutics, Bangalore-560058, India.
authors.forename: Sankareswaran
authors.initials: S
authors.lastname: Srimurugan
authors.forename: Paulsamy
authors.initials: P
authors.lastname: Suresh
authors.forename: Balaji
authors.initials: B
authors.lastname: Babu
authors.forename: Salmara Ganeshbhat
authors.initials: SG
authors.lastname: Hiriyanna
authors.forename: Hari Narayan
authors.initials: HN
authors.lastname: Pati
mesh_terms: D047228:Angiotensin II Type 1 Receptor Blockers / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D007093:Imidazoles / Q000737:chemistry; D007553:Isotope Labeling; D013777:Tetrazoles / Q000737:chemistry*; D014316:Tritium / Q000737:chemistry
chemical_list: D047228:Angiotensin II Type 1 Receptor Blockers; D007093:Imidazoles; D013777:Tetrazoles; D014316:Tritium; C437965:olmesartan