Complications associated with transcatheter closure of perimembranous ventricular septal defects.
OBJECTIVE
To identify the complications associated with transcatheter closure of perimembranous ventricular septal defects (PmVSD) using the Amplazter PmVSD occluder (AGA Medical, USA).


METHODS
Between October 2002 and November 2006, transcatheter closure PmVSD was attempted in 210 patients and performed in 206 patients. Those patients were followed-up for 6-24 months (mean, 10.6 +/- 3.9 months) to identify the complications.


RESULTS
Device implantation was successfully accomplished in 206 of the 210 patients (98%). Serious complications such as high degree atrioventricular block (AV block), infective endocarditis, and device embolization occurred in eight cases (3.8%). Other complications including mild aortic or tricuspid regurgitation, femoral pseudoaneurysm, and femoral arteriovenous fistula occurred in four cases.


CONCLUSIONS
Transcatheter closure of PmVSD can be performed safely and successfully. But further studies should continue to evaluate the potential complications associated with this procedure.
Zhou
Tao
T
Department of Cardiology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China. zhoutao6240@yahoo.com
Shen
Xiang-Qian
XQ
Zhou
Sheng-Hua
SH
Fang
Zhen-Fei
ZF
Hu
Xin-Qun
XQ
Zhao
Yan-Shu
YS
Qi
Shu-Shan
SS
Li
Jiang
J
Lv
Xiao-Lin
XL
D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization / Q000009:adverse effects*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D018618:Echocardiography, Doppler, Color; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome