title: Giant cell reparative granuloma of the cranial vault-case report and review of literature.
abstract: BACKGROUND
  Giant cell reparative granuloma is a condition commonly found in the facial bones. It has been reported in the skull bones, predominantly the bones comprising the skull base. Giant cell reparative granuloma of the cranial vault is exceedingly rare. Its distinction from a neoplastic lesion is difficult clinically and radiologically.
  
  
  METHODS
  Only the third case of a GCRG of the skull vault, the first in an adult, is described. Its pathophysiology and differential diagnoses influencing management are discussed.
  
  
  CONCLUSIONS
  It is not possible to diagnose this condition definitively on a clinical or radiologic basis, and given its differential diagnoses, an excision biopsy should be offered.
authors.affiliation: Department of Neurosurgery, St Bartholomew's and The Royal London Hospital, E1 1BB Whitechapel, London. nitinmukerji@hotmail.com
authors.forename: Nitin
authors.initials: N
authors.lastname: Mukerji
authors.forename: Henry
authors.initials: H
authors.lastname: Willmott
authors.forename: Anthony
authors.initials: A
authors.lastname: Joy
authors.forename: Reto
authors.initials: R
authors.lastname: Sutter
authors.forename: John
authors.initials: J
authors.lastname: Wadley
mesh_terms: D000328:Adult; D003399:Craniotomy / Q000379:methods; D004388:Dura Mater / Q000473:pathology / Q000601:surgery; D005260:Female; D006101:Granuloma, Giant Cell / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D016489:Head Injuries, Closed / Q000150:complications*; D006801:Humans; D010294:Parietal Bone / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology*; D019736:Prostheses and Implants; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000295:instrumentation / Q000379:methods; D012886:Skull / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology*; D014025:Titanium / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D014025:Titanium