Models for non-alcoholic fatty liver disease: a link with vascular risk.
Non alcoholic fatty liver disease (NAFLD) is often part of the metabolic syndrome which includes central obesity, dyslipidaemia, insulin resistance/type 2 diabetes mellitus and hypertension. In turn, NAFLD may be associated with an increased vascular risk. Several experimental models which express histological steatosis or steatohepatitis with fibrosis have been described. This review identifies those models of NAFLD with features of vascular risk.
Xirouchakis
E
E
The Sheila Sherlock Hepatobiliary Pancreatic and Liver Transplantation Unit, Royal Free Hospital, London, UK.
Sigalas
A
A
Manousou
P
P
Calvaruso
V
V
Pleguezuelo
M
M
Corbani
A
A
Maimone
S
S
Patch
D
D
Burroughs
A K
AK
D000818:Animals; D004195:Disease Models, Animal; D005234:Fatty Liver / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D006801:Humans; D018836:Inflammation Mediators / Q000378:metabolism; D012307:Risk Factors; D014652:Vascular Diseases / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology
D018836:Inflammation Mediators