The importance of left ventricular function for long-term outcome after primary percutaneous coronary intervention.
BACKGROUND
In the present study we sought to determine the long-term prognostic value of left ventricular ejection fraction (LVEF), assessed by planar radionuclide ventriculography (PRV), after ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI).


METHODS
In total 925 patients underwent PRV for LVEF assessment after PPCI for myocardial infarction before discharge from the hospital. PRV was performed with a standard dose of 500 Mbq of 99mTc-pertechnetate. Average follow-up time was 2.5 years.


RESULTS
Mean (+/- SD) age was 60 +/- 12 years. Mean (+/- SD) LVEF was 45.7 +/- 12.2 %. 1 year survival was 97.3 % and 3 year survival was 94.2 %. Killip class, multi vessel-disease, previous cardiovascular events, peak creatin kinase and its MB fraction, age and LVEF proved to be univariate predictors of mortality. When entered in a forward conditional Cox regression model age and LVEF were independent predictors of 1 and 3 year mortality.


CONCLUSIONS
LVEF assessed by PRV is a powerful independent predictor of long term mortality after PPCI for STEMI.
van der Vleuten
Pieter A
PA
Thoraxcentre, Department of Cardiology, University Medical Centre Groningen, The Netherlands. p.a.van.der.vleuten@thorax.umcg.nl
Rasoul
Saman
S
Huurnink
Willem
W
van der Horst
Iwan Cc
IC
Slart
Riemer Hja
RH
Reiffers
Stoffer
S
Dierckx
Rudi A
RA
Tio
René A
RA
Ottervanger
Jan Paul
JP
De Boer
Menko-Jan
MJ
Zijlstra
Felix
F
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000401:mortality* / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D016016:Proportional Hazards Models; D015635:Radionuclide Ventriculography; D012042:Registries; D012307:Risk Factors; D013318:Stroke Volume; D016277:Ventricular Function, Left