Oral administration of the antiobesity drugs, sibutramine and rimonabant, increases acetylcholine efflux selectively in the medial prefrontal cortex of the rat.
Davis
R J
RJ
Nomikos
G G
GG
D000109:Acetylcholine / Q000378:metabolism*; D000284:Administration, Oral; D000704:Analysis of Variance; D000818:Animals; D001067:Appetite Depressants / Q000008:administration & dosage*; D003503:Cyclobutanes / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D008297:Male; D017551:Microdialysis / Q000379:methods; D009714:Nucleus Accumbens / Q000187:drug effects; D010880:Piperidines / Q000008:administration & dosage*; D017397:Prefrontal Cortex / Q000187:drug effects* / Q000378:metabolism; D011720:Pyrazoles / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D000077285:Rimonabant
D001067:Appetite Depressants; D003503:Cyclobutanes; D010880:Piperidines; D011720:Pyrazoles; D000109:Acetylcholine; D000077285:Rimonabant; C058254:sibutramine