title: Impact of anti-tuberculosis therapy on plasma zinc status in childhood tuberculosis.
abstract: This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis (71.7 microg/dL) were not significantly different than the other 2 groups (72.5 and 76.9 microg/dL). The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment.
authors.affiliation: National Research Institute of Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors.forename: M R
authors.initials: MR
authors.lastname: Boloorsaz
authors.forename: S
authors.initials: S
authors.lastname: Khalilzadeh
authors.forename: A R
authors.initials: AR
authors.lastname: Milanifar
authors.forename: A
authors.initials: A
authors.lastname: Safavi
authors.forename: A A
authors.initials: AA
authors.lastname: Velayati
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects*; D001798:Blood Proteins / Q000378:metabolism; D016022:Case-Control Studies; D002648:Child; D015362:Child Nutrition Disorders / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D002675:Child, Preschool; D023801:Directly Observed Therapy / Q000009:adverse effects; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D007223:Infant; D007492:Iran; D008297:Male; D015596:Nutrition Assessment; D009752:Nutritional Status; D012709:Serum Albumin / Q000378:metabolism; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy*; D015032:Zinc / Q000097:blood / Q000172:deficiency
chemical_list: D000995:Antitubercular Agents; D001798:Blood Proteins; D012709:Serum Albumin; D015032:Zinc