title: Sickle cell nephropathy with diffuse proliferative lupus nephritis: a case report.
abstract: BACKGROUND
  Sickle cell nephropathy (SCN) is an important cause of mortality in patients with sickle cell disease. SCA with systemic lupus erythematosus (SLE) is known in children and less common in adults, however diffuse proliferative lupus nephritis (DPLN) with SCN has rarely been reported in adults. It requires early diagnosis and aggressive management.
  
  
  METHODS
  We present here a 35 years old lady with sickle cell disease who presented with edema, dyspnoea on exertion, pyuria and had raised s. creatinine of 7 mg%. Her biopsy revealed SCN with DPLN. She is on maintenance hemodialysis after 2 months of diagnosis.
  
  
  CONCLUSIONS
  DPLN with SCN is a rare entity with poor prognosis, which may be overlooked and needs aggressive management.
authors.affiliation: Department of Pathology, Laboratory Medicine and Transfusion Services, and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre and Dr. H. L. Trivedi Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad, India. kamalkanodia@yahoo.com
authors.forename: Kamal V
authors.initials: KV
authors.lastname: Kanodia
authors.forename: Aruna V
authors.initials: AV
authors.lastname: Vanikar
authors.forename: Kamal R
authors.initials: KR
authors.lastname: Goplani
authors.forename: Sonia B
authors.initials: SB
authors.lastname: Gupta
authors.forename: Hargovind L
authors.initials: HL
authors.lastname: Trivedi