title: Active management of incipient caries and choice of materials.
abstract: Evidence of the effects of various sealant and fluoride materials in stabilizing or reversing incipient caries lesions has been reported. However, a knowledge gap still exists as to what material yields the best results. Thus, the objective of this study was to find the most effective material by comparing the effects of a resin-based sealant (sealant), a fluoride-containing sealant (F-sealant), a fluoride varnish (F-varnish), and a glass-ionomer cement (GIC) on de-remineralization of incipient artificial caries and adjacent intact enamel on proximal surfaces of posterior teeth. The 4 materials were applied to lesions created on proximal surfaces. Areas of intact enamel 0.5 mm adjacent to the materials were also studied. The specimens were thermo- and pH-cycled. Cross-sections of the two areas were analyzed under polarized light microscope and quantified with Image-Pro plus. The most effective material in reducing the carious areas was GIC, followed by F-varnish, F-sealant, and sealants. GIC followed by F-varnish was most efficient in inhibiting new caries lesions 0.5 mm adjacent to the materials.
authors.affiliation: Department of Pediatric Dentistry, Chulalongkorn University, 34 Henri Dunant Road, Pathumwan, Bangkok 10330, Thailand. ctrairat@yahoo.com
authors.forename: C
authors.initials: C
authors.lastname: Trairatvorakul
authors.forename: S
authors.initials: S
authors.lastname: Kladkaew
authors.forename: S
authors.initials: S
authors.lastname: Songsiripradabboon
mesh_terms: D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use; D003731:Dental Caries / Q000473:pathology / Q000517:prevention & control / Q000628:therapy*; D003743:Dental Enamel / Q000187:drug effects / Q000473:pathology; D003764:Dental Materials; D005459:Fluorides / Q000627:therapeutic use; D005460:Fluorides, Topical / Q000627:therapeutic use; D005899:Glass Ionomer Cements; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007091:Image Processing, Computer-Assisted; D008859:Microscopy, Polarization; D010895:Pit and Fissure Sealants / Q000627:therapeutic use; D012464:Saliva, Artificial; D012969:Sodium Fluoride; D013696:Temperature; D014089:Tooth Remineralization
chemical_list: D002327:Cariostatic Agents; D003764:Dental Materials; D005460:Fluorides, Topical; C493186:Fuji VII; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; D012464:Saliva, Artificial; C023807:sodium fluoride topical preparation; C099291:teethmate-FTM; D017438:Bisphenol A-Glycidyl Methacrylate; D012969:Sodium Fluoride; D005459:Fluorides