title: Brucellosis: a retrospective evaluation of 99 cases and review of brucellosis treatment.
abstract: This retrospective study was performed in two university hospitals between January 2002 and 2006. Ninety-nine brucellosis patients were included in the study. These patients were classified as acute (91), chronic (4) and relapse (4) according to their clinical presentations and serological tests. Brucella bacteria were isolated in the blood of 17 (17.2%) cases. The most frequent symptom and clinical sign was fever. The osteoarticular complications were found in 17 patients (17.2%). Four of them were complicated with epidural abscess the same time. Two (2.2%) had meningitis, two (2.2%) had epididymoorchitis, three (3.3%) had skin rashes and one (1.1%) had hepatitis. Three of the acute brucellosis patients were pregnant. Rifampin and doxycycline combination therapy had been administered to most of the patients with acute and relapse brucellosis. However, complicated and chronic brucellosis cases were given different treatment combinations. This study reviews brucellosis therapy choices.
authors.affiliation: Department of Infectious Disease and Clinical Microbiology, Kocatepe University, Afyon, Turkey. nesed60@hotmail.com
authors.forename: Neşe
authors.initials: N
authors.lastname: Demirtürk
authors.forename: Tuna
authors.initials: T
authors.lastname: Demirdal
authors.forename: Nurettin
authors.initials: N
authors.lastname: Erben
authors.forename: Serap
authors.initials: S
authors.lastname: Demir
authors.forename: Zerrin
authors.initials: Z
authors.lastname: Asci
authors.forename: Turkan Pasali
authors.initials: TP
authors.lastname: Kilit
authors.forename: Elif Doyuk
authors.initials: ED
authors.lastname: Kartal
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000635:transmission; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents