title: [Effect of dosed normobaric hypoxia on the bone tissue physiological regeneration].
abstract: We investigated the effect of dosed normobaric hypoxic gas mixtures with reduced oxygen partial pressure in the different modes on stimulation of the physiological bone tissue regeneration process in adult rats. It is shown that nitrogen and oxygen gas mixture (Po2 = 76 mm Hg) application in the modes 10 min deoxygenation--10 min reoxygenation during 4 hours daily or during 1 hour continuously is the optimum for an increase of biochemical markers of physiological regeneration of bone tissue.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Berezovs'kyĭ
authors.forename: I H
authors.initials: IH
authors.lastname: Litovka
authors.forename: O S
authors.initials: OS
authors.lastname: Kostiuchenko
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001861:Bone Regeneration / Q000502:physiology*; D001842:Bone and Bones / Q000378:metabolism / Q000502:physiology*; D013006:Growth Hormone / Q000378:metabolism; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010281:Parathyroid Hormone / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
chemical_list: D015415:Biomarkers; D010281:Parathyroid Hormone; D013006:Growth Hormone