title: Effectiveness of the novel anti-diabetes medication exenatide in everyday practice: Comparison with clinical trials.
abstract: We evaluated effectiveness of exenatide in 81 unselected patients and compared the results with clinical trials. Patients achieved a similar reduction in A1C and lost more weight than patients in the clinical trials. Thirty-seven (46%) were treated off-label. Exenatide was effective on and off-label in this unselected patient group.
authors.affiliation: Department of Medicine, Union Memorial Hospital, Baltimore, MD, USA.
authors.forename: Sirisha
authors.initials: S
authors.lastname: Donekal
authors.forename: Mansur E
authors.initials: ME
authors.lastname: Shomali
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D000077270:Exenatide; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010455:Peptides / Q000627:therapeutic use*; D016896:Treatment Outcome; D014688:Venoms / Q000627:therapeutic use*
chemical_list: D007004:Hypoglycemic Agents; D010455:Peptides; D014688:Venoms; D000077270:Exenatide