Serum alpha-1-antitriypsin levels in patients with pseudoexfolative syndrome.
OBJECTIVE
To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX.


METHODS
Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry.


RESULTS
The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001).


CONCLUSIONS
Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
Cumurcu
Tongabay
T
Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. tongabay@superonline.com
Ozyurt
Huseyin
H
Demir
Helin Deniz
HD
Yardim
Huseyin
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017889:Exfoliation Syndrome / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D000515:alpha 1-Antitrypsin / Q000097:blood*
C043392:SERPINA1 protein, human; D000515:alpha 1-Antitrypsin