title: A long-term durable remission with high-dose therapy and autologous stem cell transplant for stage IVB HIV-associated Hodgkins disease.
abstract: A 44-year-old man with relapsed HIV-associated stage IV nodular sclerosing Hodgkin's disease underwent high-dose therapy with autologous stem cell transplantation. The transplant was uncomplicated and the patient remains in complete remission at 59 months. Autologous stem cell transplantation is safe in HIV patients and can achieve long-term durable remissions in Hodgkin's disease.
authors.affiliation: Department of Clinical Haematology, Hammersmith Hospital, London, UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Gabriel
authors.forename: Jane
authors.initials: J
authors.lastname: Apperley
authors.forename: Mark
authors.initials: M
authors.lastname: Bower
authors.forename: Aristeidis
authors.initials: A
authors.lastname: Chaidos
authors.forename: Brian
authors.initials: B
authors.lastname: Gazzard
authors.forename: Chrissy
authors.initials: C
authors.lastname: Giles
authors.forename: Andrea
authors.initials: A
authors.lastname: Kew
authors.forename: Mark
authors.initials: M
authors.lastname: Nelson
authors.forename: Ed
authors.initials: E
authors.lastname: Kanfer
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D023241:Antiretroviral Therapy, Highly Active; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D008130:Lomustine / Q000008:administration & dosage; D016483:Lymphoma, AIDS-Related / Q000628:therapy*; D008297:Male; D012074:Remission Induction / Q000379:methods; D014182:Transplantation, Autologous
chemical_list: D003561:Cytarabine; D005047:Etoposide; D008130:Lomustine; D003520:Cyclophosphamide