title: [Prevention of intrauterine adhesions after hysteroscopic surgery].
abstract: Intrauterine adhesions are the most frequent complications after hysteroscopic surgery in women of reproductive age. The prevalence of intrauterine adhesions after hysteroscopic surgery is correlated to intrauterine pathology (myoma, polyp, or adhesions). Few clinical trials have demonstrated the efficiency of barrier agents developed in order to prevent adhesions after operative hysteroscopy. Adhesion barriers are mechanic agent (intrauterine device), fluid agents (Seprafilm, Hyalobarrier) and postoperative systemic treatment (estroprogestative treatment). In this article, we evaluate the efficiency of these barrier agents for adhesion prevention in hysteroscopic surgery, undertaking a review of clinical trials published. The most frequent published studies evaluate the anatomic efficiency of antiadhesion agents after hysteroscopic surgery in order to evaluate the fertility. Data are still insufficient to evaluate them for clinical use. There is a need for other randomised controlled trials.
authors.affiliation: Service de chirurgie gynécologique et d'obstétrique, université Paris-VII, hôpital Beaujon, Assistance publique-Hôpitaux de Paris (AP-HP), 100 boulevard du Général-Leclerc, Clichy, France.
authors.forename: A
authors.initials: A
authors.lastname: Revaux
authors.forename: G
authors.initials: G
authors.lastname: Ducarme
authors.forename: D
authors.initials: D
authors.lastname: Luton
mesh_terms: D002483:Cellulose, Oxidized / Q000009:adverse effects / Q000627:therapeutic use; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000009:adverse effects / Q000627:therapeutic use; D015907:Hysteroscopy / Q000009:adverse effects*; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene / Q000009:adverse effects / Q000627:therapeutic use; D011183:Postoperative Complications / Q000517:prevention & control*; D016032:Randomized Controlled Trials as Topic; D012449:Safety; D000267:Tissue Adhesions / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D002483:Cellulose, Oxidized; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D006820:Hyaluronic Acid