[Pathophysiology of biliary lithiasis].
Gallstones affect about 15% of adults in Europe. Cholesterol gallstone is the common form of the disease. Pigment stones, resulting from bilirubin precipitation feature particular clinical settings such as chronic hemolysis, intestinal malabsorption and various biliary tract diseases. Supersaturation of bile with cholesterol, increased formation of deoxycholic acid and gallbladder hypomotility are the main factors involved in gallstones pathogenesis.
Poupon
Raoul
R
Service d'hépatologie, hôpital Saint-Antoine, 75571 Paris Cedex 12. raoul.poupon@sat.aphp.paris.fr
D002769:Cholelithiasis / Q000737:chemistry / Q000503:physiopathology*; D002784:Cholesterol / Q000032:analysis; D006801:Humans
D002784:Cholesterol