title: Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects.
abstract: In this study we aimed to investigate the relationship between anhedonia, craving and temperament and character dimensions in a sample of 50 patients with alcohol and opiate dependence recruited after a period of detoxification. The following scales were applied: Snaith-Hamilton Pleasure Scale (SHAPS), Bech-Rafaelsen Melancholia Scale (BRMS), Scale for the Assessment of Negative Symptoms (SANS), Visual Analogue Scales (VAS) for craving, and Temperament and Character Inventory (TCI). The temperament dimension of Novelty Seeking was positively correlated to craving and anhedonia (p < .01), with a higher score of Novelty Seeking in the subsample of anhedonic subjects with respect to both non-anhedonic and control subjects. In our study, the possibility that difficulty in experiencing pleasure in psychiatric disorders can lead to the use of psychoactive substances in an attempt to decrease anhedonia, is extended to subjects without psychiatric disorders who may try substances to counterbalance a tonic state of anhedonia.
authors.affiliation: Department of Psychiatry, Drug Addiction Unit, Catholic University Medical School, Rome, Italy. giovanni.martinotti@libero.it
authors.forename: G
authors.initials: G
authors.lastname: Martinotti
authors.forename: C R
authors.initials: CR
authors.lastname: Cloninger
authors.forename: L
authors.initials: L
authors.lastname: Janiri
mesh_terms: D000328:Adult; D000342:Affective Symptoms; D000437:Alcoholism / Q000523:psychology* / Q000534:rehabilitation; D016739:Behavior, Addictive / Q000523:psychology*; D016022:Case-Control Studies; D002605:Character; D005260:Female; D006801:Humans; D008658:Inactivation, Metabolic; D008297:Male; D016555:Matched-Pair Analysis; D009293:Opioid-Related Disorders / Q000523:psychology* / Q000534:rehabilitation; D055502:Secondary Prevention; D013694:Temperament