title: Laser in situ keratomileusis following the implantation of iris-fixated phakic intraocular lenses.
abstract: OBJECTIVE
  This study aims to assess the safety, efficacy, predictability, stability and complications associated with laser in situ keratomileusis (LASIK) for the correction of residual refractive errors following implantation of iris-fixated phakic intraocular lenses (pIOLs).
  
  
  METHODS
  In this retrospective interventional case series of 92 eyes, an iris-fixated pIOL (Artisan) was implanted to correct myopia and myopic astigmatism. In 10 eyes, a residual refractive error was treated using LASIK. Visual acuity testing, subjective refraction, slitlamp examination and tonometry were all performed preoperatively, then 3 months following pIOL implantation and 1 year after LASIK treatment. The endothelial cell density was measured both prior to pIOL implantation and following LASIK therapy.
  
  
  RESULTS
  Comparison of preoperative and postoperative best-corrected visual acuity revealed that none of the combined operated eyes forfeited > or =2 lines of visual acuity after LASIK. Uncorrected visual acuity for all 10 eyes after LASIK was > or =0.8. LASIK made a 61.5% mean reduction in astigmatism possible. Compared to the initial examination, the mean endothelial cell loss after LASIK treatment was 4.1%.
  
  
  CONCLUSIONS
  For correction of residual refractive errors following iris-fixated phakic IOL implantation, LASIK appears to be a safe and effective procedure. Larger numbers of patients are required to verify this conclusion.
authors.affiliation: Department of Ophthalmology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Meltendorf
authors.forename: Magdalena
authors.initials: M
authors.lastname: Cichocki
authors.forename: Thomas
authors.initials: T
authors.lastname: Kohnen
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000209:etiology / Q000601:surgery*; D002452:Cell Count; D015331:Cohort Studies; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D007498:Iris; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008137:Longitudinal Studies; D008875:Middle Aged; D009216:Myopia / Q000209:etiology / Q000601:surgery*; D011184:Postoperative Period; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity