title: A non-human primate model of acute group a Streptococcus pharyngitis.
abstract: This chapter describes methods for using non-human primates as a model of group A streptococcal (GAS) pharyngitis. This model has been used successfully to study host-pathogen interactions occurring during pharyngeal GAS infections. The protocol as described will compare two different GAS strains for their ability to cause clinical symptoms of pharyngitis.
authors.affiliation: Center for Molecular and Translational Hman Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Sumby
authors.forename: Anne H
authors.initials: AH
authors.lastname: Tart
authors.forename: James M
authors.initials: JM
authors.lastname: Musser
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D010612:Pharyngitis / Q000382:microbiology*; D011323:Primates / Q000382:microbiology*; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000254:growth & development*