title: Antimicrobial prophylaxis for wounds and procedures in the emergency department.
abstract: Emergency physicians are often confronted with situations in which a patient with an acute injury is at high risk for an infection. Although most traumatic wounds have a low risk for developing infection, certain types of high-risk trauma justify antimicrobial prophylaxis. This article reviews antimicrobial wound infection prophylaxis for high-risk traumatic wounds, including the prevention of rabies and tetanus. Prophylaxis to prevent infections related to invasive procedures in the emergency department is also addressed.
authors.affiliation: David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA. gmoran@ucla.edu
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Moran
authors.forename: David A
authors.initials: DA
authors.lastname: Talan
authors.forename: Fredrick M
authors.initials: FM
authors.lastname: Abrahamian
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control*; D004635:Emergency Medicine / Q000379:methods*; D006801:Humans; D011818:Rabies / Q000188:drug therapy; D013742:Tetanus / Q000188:drug therapy / Q000517:prevention & control; D013745:Tetanus Toxoid / Q000627:therapeutic use; D014947:Wounds and Injuries / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D013745:Tetanus Toxoid