Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women.
Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens > or = 95% of the time (AOR = 1.39, 95% CI = 1.01-1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.
Kapadia
Farzana
F
Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, New York, USA.
Vlahov
David
D
Wu
Yingfeng
Y
Cohen
Mardge H
MH
Greenblatt
Ruth M
RM
Howard
Andrea A
AA
Cook
Judith A
JA
Goparaju
Lakshmi
L
Golub
Elizabeth
E
Richardson
Jean
J
Wilson
Tracey E
TE
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D015999:Multivariate Analysis; D010349:Patient Compliance; D011446:Prospective Studies; D012044:Regression Analysis; D015819:Substance Abuse, Intravenous / Q000453:epidemiology / Q000534:rehabilitation*; D014481:United States / Q000453:epidemiology