Hashimoto's encephalopathy masquerading as acute psychosis.
Hashimoto's encephalopathy (HE) is a relapsing, but exquisitely corticosteroid-responsive encephalopathy associated with autoimmune thyroiditis. Although a rare disease, with just over 100 cases reported, it may be under-recognised. Its presentation can be protean with prominent neuropsychiatric features, stroke-like episodes, seizures and myoclonic jerks. Prompt corticosteroid treatment usually leads to rapid recovery. Here we report a patient with HE, initially presenting with florid neuropsychiatric symptoms. Recent developments in the understanding of this condition are discussed.
Wilcox
R A
RA
Department of Neurology, Level 2, Flinders Medical Centre, Bedford Park, Adelaide 5042, South Australia, Australia.
To
T
T
Koukourou
A
A
Frasca
J
J
D000208:Acute Disease; D000328:Adult; D001927:Brain Diseases / Q000150:complications* / Q000473:pathology; D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000379:methods; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D011618:Psychotic Disorders / Q000209:etiology*