Primary laryngeal natural killer/T-cell lymphoma--report of a rare case.
BACKGROUND
Natural killer (NK)/T-cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described.


RESULTS
A 73-year-old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T-cell lymphoma. This patient died of the disease despite the use of chemotherapy.


CONCLUSIONS
To the best of our knowledge, this is the second case of primary laryngeal NK/T-cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor-like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations.
Monobe
Hiroko
H
Department of Otolaryngology, Hitachi General Hospital, Ibaraki, Japan. hiroko.monobe.rw@hitachi.com
Nakashima
Masato
M
Tominaga
Kunihiko
K
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D007694:Killer Cells, Natural; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male