title: Progressive macular hypomelanosis in a 16-year old.
abstract: Progressive macular hypomelanosis of the trunk is a disease of unclear etiology that often goes unrecognized in the clinical setting. We present a Caucasian adolescent girl with hypopigmented macules coalescing into patches on her trunk, initially diagnosed as tinea versicolor. Upon further evaluation, the patient was found to have progressive macular hypomelanosis that demonstrated improvement with sunlight exposure and doxycycline. We report this patient to make physicians more aware of this entity and discuss the literature.
authors.affiliation: Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, Ohio 45229, USA.
authors.forename: Marissa
authors.initials: M
authors.lastname: Perman
authors.forename: Pranav
authors.initials: P
authors.lastname: Sheth
authors.forename: Anne W
authors.initials: AW
authors.lastname: Lucky
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D018450:Disease Progression; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017496:Hypopigmentation / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D007150:Immunohistochemistry; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000473:pathology; D012720:Severity of Illness Index; D012867:Skin / Q000378:metabolism* / Q000473:pathology; D014010:Tinea Versicolor / Q000175:diagnosis* / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D008543:Melanins; D004318:Doxycycline