title: A review and meta-analysis of the impact of intestinal worms on child growth and nutrition.
abstract: More than a half of the world's population are infected with one or more species of intestinal worms of which the nematodes Ascaris lumbricoides, Trichuris trichiura and the hookworms are the most common and important in terms of child health. This paper: (1) introduces the main species of intestinal worms with particular attention to intestinal nematodes; (2) examines how such worms may affect child growth and nutrition; (3) reviews the biological and epidemiological factors that influence the effects that worms can have on the growth and nutrition of children; (4) considers the many factors that can affect the impact of treatment with anthelmintic drugs; (5) presents the results of a meta-analysis of studies of the effect of treating worm infections on child growth and nutrition; (6) discusses the results in terms of what is reasonable to expect that deworming alone can achieve; (7) describes some important characteristics of an ideal study of the effects of deworming; and (8) comments on the implications for programmes of recommendations concerning mass deworming.
authors.affiliation: Centre for Public Health Nutrition, University of Westminster, London, UK. a.hall04@westminster.ac.uk
authors.forename: Andrew
authors.initials: A
authors.lastname: Hall
authors.forename: Gillian
authors.initials: G
authors.lastname: Hewitt
authors.forename: Veronica
authors.initials: V
authors.lastname: Tuffrey
authors.forename: Nilanthi
authors.initials: N
authors.lastname: de Silva
mesh_terms: D000871:Anthelmintics / Q000627:therapeutic use; D002648:Child; D002657:Child Development; D015362:Child Nutrition Disorders / Q000209:etiology*; D002664:Child Nutritional Physiological Phenomena / Q000502:physiology*; D002675:Child, Preschool; D003071:Cognition; D005260:Female; D006128:Growth; D006801:Humans; D007223:Infant; D007411:Intestinal Diseases, Parasitic / Q000150:complications* / Q000188:drug therapy / Q000517:prevention & control*; D008297:Male; D009752:Nutritional Status; D015430:Weight Gain
chemical_list: D000871:Anthelmintics