title: Synthesis and absolute configuration of hormone alpha1.
abstract: An important biological event in phytopathogens of the genus Phytophthora is sexual reproduction, which is conducted by two mating types, A1 and A2. A factor known as hormone alpha1 is secreted by the A1 mating type and induces the formation of sexual spores (oospores) in the A2 mating type. Here we describe the asymmetric synthesis and assignment of the absolute configuration of hormone alpha1 by oospore-inducing assays of the synthesized isomers.
authors.affiliation: Department of Fermentation Science, Faculty of Applied Biological Science, Tokyo University of Agriculture, Sakuragaoka 1-1-1, Setagaya-ku, Tokyo 156-8502, Japan. ayaji@nodai.ac.jp
authors.forename: Arata
authors.initials: A
authors.lastname: Yajima
authors.forename: Yong
authors.initials: Y
authors.lastname: Qin
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhou
authors.forename: Naoki
authors.initials: N
authors.lastname: Kawanishi
authors.forename: Xue
authors.initials: X
authors.lastname: Xiao
authors.forename: Jue
authors.initials: J
authors.lastname: Wang
authors.forename: Dan
authors.initials: D
authors.lastname: Zhang
authors.forename: Yi
authors.initials: Y
authors.lastname: Wu
authors.forename: Tomoo
authors.initials: T
authors.lastname: Nukada
authors.forename: Goro
authors.initials: G
authors.lastname: Yabuta
authors.forename: Jianhua
authors.initials: J
authors.lastname: Qi
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Asano
authors.forename: Youji
authors.initials: Y
authors.lastname: Sakagami
mesh_terms: D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry*; D005656:Fungal Proteins / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008968:Molecular Conformation; D010316:Particle Size; D010838:Phytophthora / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; D005656:Fungal Proteins; C504077:mating hormone alpha1, Phytophthora