title: Numb chin syndrome: the presenting symptom of a metastatic prostate carcinoma.
abstract: Numb chin syndrome is a sensory neuropathy characterized by numbness involving the distribution of the mental nerve that could be an uncommon manifestation of metastatic malignancy. Bony metastases are common in patients with advanced prostate carcinoma and involving preferentially vertebrae, sternum, pelvic bones, ribs and femurs. We report a case in an 82-year-old man presenting a history of mental neuropathy as the isolated presenting symptom of a widespread metastatic prostate cancer Numb chin syndrome was describe in some reviews as a late component of a previously diagnosed disease but this report underline the importance of this neuropathy as the isolated presenting symptom of a widespread metastatic prostate cancer. This event is very rare and enumerates four cases in the world literature.
authors.affiliation: Urology Department, San Gerardo Hospital, Monza, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Viganò
authors.forename: Stefano Carlo Maria
authors.initials: SC
authors.lastname: Picozzi
authors.forename: Alfio
authors.initials: A
authors.lastname: Giuberti
authors.forename: Marilena
authors.initials: M
authors.lastname: Casu
authors.forename: Vittorio
authors.initials: V
authors.lastname: Manganini
authors.forename: Luciano
authors.initials: L
authors.lastname: Mazza
authors.forename: Guido Raffaele
authors.initials: GR
authors.lastname: Strada
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000556:secondary*; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000150:complications* / Q000556:secondary*; D005155:Facial Nerve Diseases / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male