Electrocardiographic findings of acute organophosphate poisoning.
In this study, we evaluated 85 patients who presented to our Emergency Department with organophosphate (OP) poisoning and discuss their associated electrocardiographic (ECG) abnormalities. Over a period of 3 years, 85 patients with OP poisoning were included in this retrospective study. ECG analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. The mean age was 32.2 +/- 14.9 years. Sixty percent of the patients were female. The mean corrected QT interval (QTc interval) was 0.435 +/- 0.052 s. Prolongation of the QTc interval (55.5%) was the most common ECG abnormality, followed by sinus tachycardia (31.8%). Elevation of the ST segment and low amplitude T waves were seen in 15 cases (17.6%). Patients with OP poisoning might reveal ECG abnormalities such as QTc interval prolongation or non-specific ST-T changes. QTc interval prolongation cannot be used as a unique predictive factor in determining short-term prognosis in OP poisoning. We found no clear relation between OP poisoning-related malignant ventricular dysrhythmia and QTc interval.
Yurumez
Yusuf
Y
Department of Emergency Medicine, Kocatepe University Medical Faculty, Afyonkarahisar, Turkey.
Yavuz
Yucel
Y
Saglam
Hayrettin
H
Durukan
Polat
P
Ozkan
Seda
S
Akdur
Okhan
O
Yucel
Murat
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000382:Agricultural Workers' Diseases / Q000139:chemically induced* / Q000503:physiopathology*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology*; D002800:Cholinesterase Inhibitors / Q000506:poisoning; D015331:Cohort Studies; D004562:Electrocardiography; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning; D012189:Retrospective Studies; D014421:Turkey; D055815:Young Adult
D002800:Cholinesterase Inhibitors; D007306:Insecticides