Intracameral SF6 injection and anterior segment OCT-based documentation for acute hydrops management in pellucid marginal corneal degeneration.
OBJECTIVE
To report a case of acute hydrops in pellucid marginal corneal degeneration (PMCD) documented with anterior segment optical segment tomography and successfully treated with sulphur hexafluoride (SF6) intracameral injection.


METHODS
A 47-year-old female patient presented with spontaneous onset of pain, redness and decreased vision in her left eye. Clinical evaluation revealed bilateral PMCD with evidence of acute hydrops in the left eye. Anterior segment Slit lamp Adapted Optical Coherence Tomography (SL-OCT) examination revealed intrastromal clefts with Descemet's membrane detachment in the left eye. She was managed with descemetopexy with 0.2ml injection of iso-expansile SF6 (18%) intracameral.


RESULTS
The patient showed excellent early resolution of the stromal edema with reattachment of the Descemet's membrane.


CONCLUSIONS
Prompt intervention in acute hydrops in PMCD cases helps in achieving early good visual results and prevents potentially serious complications such as perforation. Newer imaging modalities like SL-OCT helps in better visualisation and also in monitoring the response to treatment.
Vanathi
M
M
Cornea Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. vanathi_g@yahoo.com
Behera
Geeta
G
Vengayil
Sujith
S
Panda
Anita
A
Khokhar
S
S
D000208:Acute Disease; D000867:Anterior Chamber / Q000187:drug effects; D000869:Anterior Eye Segment / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000150:complications*; D015715:Corneal Edema / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D013459:Sulfur Hexafluoride / Q000008:administration & dosage*; D016683:Supine Position; D041623:Tomography, Optical Coherence
D013459:Sulfur Hexafluoride