title: Systolic hypertension in pregnancy and cardiovascular mortality: a 44-year follow-up study.
abstract: OBJECTIVE
  To assess role of systolic hypertension during pregnancy in long-term mortality.
  
  
  METHODS
  A total of 4,090 Finnish women who delivered in the period from 1954 to 1963 were followed up for an average of 44 years. Mortality data were obtained from the Finnish cause-of-death registry. Cox-proportional hazard models were used for analysis.
  
  
  RESULTS
  Cardiovascular mortality was significantly higher among women with systolic hypertension in early or late pregnancy. Women with systolic hypertension in early pregnancy without proteinuria had a significantly increased risk for cardiovascular death. Primiparas with systolic hypertension and proteinuria had a higher risk for cardiovascular death.
  
  
  CONCLUSIONS
  By considering women with systolic hypertension in pregnancy as being at higher risk for cardiovascular diseases, there may be an opportunity to prevent untimely mortality.
authors.affiliation: Tampere School of Public Health, University of Tampere, Tampere, Finland.
authors.forename: Riitta
authors.initials: R
authors.lastname: Luoto
authors.forename: Elham
authors.initials: E
authors.lastname: Kharazmi
authors.forename: Elise
authors.initials: E
authors.lastname: Whitley
authors.forename: Jani
authors.initials: J
authors.lastname: Raitanen
authors.forename: Mika
authors.initials: M
authors.lastname: Gissler
authors.forename: Elina
authors.initials: E
authors.lastname: Hemminki
mesh_terms: D002318:Cardiovascular Diseases / Q000401:mortality*; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology; D011507:Proteinuria; D012307:Risk Factors; D013599:Systole