Reversible chronic pulmonary fibrosis associated with MMF in a pediatric patient: a case report.
We describe a case of chronic mineralizing pulmonary elastosis in a seven-yr-old boy following DD renal transplantation for Wilms tumour. Fourteen months post-transplantation he developed respiratory symptoms with lung biopsy demonstrating chronic mineralizing pulmonary elastosis thought to be secondary to immunosuppression with MMF. Symptomatic resolution occurred following MMF cessation.
Reynolds
B C
BC
Department of Renal Medicine, Royal Hospital for Sick Children, Glasgow, UK. pinkdoc@doctors.net.uk
Paton
J Y
JY
Howatson
A G
AG
Ramage
I J
IJ
D002114:Calcinosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D002908:Chronic Disease; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007223:Infant; D007668:Kidney / Q000293:injuries; D007680:Kidney Neoplasms / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D009392:Nephrectomy; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D012074:Remission Induction; D006435:Renal Dialysis; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000628:therapy
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid