A case with euprolactinemic galactorrhea induced by escitalopram.
Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is only rarely mentioned among SSRI-related side effects. Perhaps through suppression of dopamine neurotransmission releasing prolactin from tonic inhibitor control of dopamine, serotonin-enhancing antidepressants may result in a rise in prolactin levels. However, we here describe a case of euprolactinemic galactorrhea induced by the SSRI escitalopram and discuss potential mechanisms of action.
Gulsun
Murat
M
Isparta Military Hospital, Psychiatry Service, Turkey. mgulsun@gmail.com
Algul
Ayhan
A
Semiz
Umit Basar
UB
Ates
Mehmet Alpay
MA
Doruk
Ali
A
Ebrinc
Servet
S
Basoglu
Cengiz
C
Cetin
Mesut
M
D000328:Adult; D015283:Citalopram / Q000009:adverse effects* / Q000627:therapeutic use; D015897:Comorbidity; D004334:Drug Administration Schedule; D005260:Female; D005687:Galactorrhea / Q000097:blood / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D006966:Hyperprolactinemia / Q000453:epidemiology; D016584:Panic Disorder / Q000097:blood / Q000188:drug therapy*; D011388:Prolactin / Q000097:blood*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
D015283:Citalopram; D011388:Prolactin; D017367:Selective Serotonin Reuptake Inhibitors