title: Rapid intrahepatic tumor seeding after percutaneous ethanol injection therapy for hepatocellular carcinoma.
abstract: A 73-year-old man with hepatocellular carcinoma (HCC) had been treated repeatedly with transcatheter arterial embolization (TAE) and percutaneous ethanol injection therapy (PEIT) since 2000. HCC recurrence near the intrahepatic left portal vein was treated by PEIT in 2004. The patient complained of fatigue and upper abdominal pain 28 days later. Abdominocentesis and abdominal computed tomography demonstrated rupture of the recurrent HCC and multiple intrahepatic recurrences. We successfully performed emergency TAE, but the patient died of liver failure. Rapid seeding of multiple intrahepatic tumors after PEIT is a rare event, but such a possibility must be kept in mind.
authors.affiliation: The Third Department of Internal Medicine, Wakayama Medical University.
authors.forename: Hiroto
authors.initials: H
authors.lastname: Tanaka
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ueda
authors.forename: Yohei
authors.initials: Y
authors.lastname: Kida
authors.forename: Hiroko
authors.initials: H
authors.lastname: Fukuchi
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ichinose
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects* / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage / Q000009:adverse effects*; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy*; D053783:Magnetic Resonance Imaging, Interventional; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000970:Antineoplastic Agents; D000431:Ethanol