Investigation of in vitro anthelmintic activities of Pycnanthus angolensis and Sphenocentrum jollyanum.
Extracts from Pycnanthus angolensis stem bark, and fruits and seeds of Sphenocentrum jollyanum, when tested in vitro, showed potent anthelmintic activity on the earthworm, Eudrilus eugeniae. Methanolic extract of P. angolensis was more active than its chloroform extract (P<0.001), while fruit ethanolic extract of S. jollyanum was also more potent than the seed extract. When compared with other worms, S. jollyanum fruit extract showed the greatest activity on wireworms when tested at 80 mg/ml.
Gbolade
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Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, Nigeria. adegbolade@yahoo.com
Adeyemi
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D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D005638:Fruit; D006188:Haemonchiasis / Q000188:drug therapy; D006189:Haemonchus / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D029583:Menispermaceae; D026324:Myristicaceae; D009835:Oligochaeta / Q000187:drug effects; D021261:Parasitic Sensitivity Tests; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012639:Seeds; D013621:Taenia / Q000187:drug effects
D000871:Anthelmintics; D010936:Plant Extracts