Acquired zinc deficiency acrodermatitis associated with nephrotic syndrome.
We present a child with new-onset nephrotic syndrome, acrodermatitis, low serum zinc levels and decreased serum alkaline phosphatase. A diagnosis of acquired zinc deficiency acrodermatitis was made. Oral zinc supplementation led to rapid clinical resolution. The etiology of zinc deficiency in nephrotic syndrome remains unknown.
Shah
Kara N
KN
Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Yan
Albert C
AC
D000169:Acrodermatitis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D000469:Alkaline Phosphatase / Q000097:blood*; D001707:Biopsy, Needle; D002648:Child; D003677:Deficiency Diseases / Q000150:complications / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007868:Leg Dermatoses / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D015032:Zinc / Q000097:blood / Q000172:deficiency* / Q000627:therapeutic use
D000469:Alkaline Phosphatase; D015032:Zinc