title: [Asymptomatic bacteruiria frequency in pregnant women and uropathogen in vitro antimicrobial sensitivity].
abstract: OBJECTIVE
  To estimate the frequency of asymptomatic bacteriuria in pregnant women attended in Family Medicine Units of the Instituto Mexicano del Seguro Social and to determine the in vitro sensitivity rate of the microorganisms to ampicillin, trimethoprim-sulfamethoxazole, nitrofurantoin and amikacin.
  
  
  METHODS
  We carried out an observational, prospective and transversal study at Family Medicine Units 62 and 64 of the Mexico State Delegation, located in the urban area of Mexico City. Women with lesser than 32 weeks of pregnancy without urinary tract symptoms were included. Urine culture of a midstream urine specimen with > or = 10(5) colony forming units/mL urine of an only germen was used as the gold standard. The in vitro antimicrobial sensitivity was established according to the Bauer Kirby technique.
  
  
  RESULTS
  874 pregnant women were included and 73 had a positive urine culture, with a frequency of 8.4%, IC 95% = 6.6 - 10.2%, of asymptomatic bacteriuria. Escherichia coil was the most frequent isolated agent (77%). In vitro sensitivity to ampicillin of the microorganisms isolated was of 27%, IC 95% = 16 - 38%; to trimethoprim-sulfamethoxazole of 40%, IC95% = 29 - 51%; to amikacin of 68%, IC 95% = 57 - 79%, and to nitrofurantoin of 79%, IC 95% = 70 - 88%.
  
  
  CONCLUSIONS
  The frequency of asymptomatic bacteriuria in the studied population is similar to the reported by the literature. The in vitro sensitivity rates of E. coil to ampicillin and to trimethoprim-sulfamethoxazole are very low. The best sensitivity corresponded to the nitrofurantoin. The treatment of the asymptomatic bacteriuria must be based on the local patterns of antimicrobial sensitivity and resistance.
authors.affiliation: Unidad de Medicina Familiar número 62, Delegación Estado de México Oriente del Instituto Mexicano del Seguro Social.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Hernández Blas
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: López Carmona
authors.forename: José Raymundo
authors.initials: JR
authors.lastname: Rodríguez Moctezuma
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Peralta Pedrero
authors.forename: Román Salvador
authors.initials: RS
authors.lastname: Rodríguez Gutiérrez
authors.forename: Alma Rosa
authors.initials: AR
authors.lastname: Ortiz Aguirre
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects*; D001437:Bacteriuria / Q000188:drug therapy* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D015994:Incidence; D010507:Periodicity; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D000890:Anti-Infective Agents