Beta-cell replication by loosening the brakes of glucagon-like peptide-1 receptor signaling.
Schuit
Frans C
FC
Gene Expression Unit, Department of Molecular Cell Biology, Katholieke Universiteit Leuven, Belgium. frans.schuit@med.kuleuven.be
Drucker
Daniel J
DJ
D049109:Cell Proliferation; D003920:Diabetes Mellitus / Q000378:metabolism*; D052216:Glucagon-Like Peptide 1 / Q000378:metabolism*; D000067757:Glucagon-Like Peptide-1 Receptor; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D050417:Insulin-Secreting Cells / Q000166:cytology* / Q000187:drug effects; D034622:RNA Interference; D012333:RNA, Messenger / Q000378:metabolism; D018027:Receptors, Glucagon / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
C000593833:GLP1R protein, human; D000067757:Glucagon-Like Peptide-1 Receptor; D007004:Hypoglycemic Agents; D012333:RNA, Messenger; D018027:Receptors, Glucagon; D052216:Glucagon-Like Peptide 1