title: Monte Carlo studies on the influence of focal spot size and intensity distribution on spatial resolution in magnification mammography.
abstract: Magnification is a special technique applied in mammography in cases where breast complaints have already been noticed, aiming to examine a specific area of the breast. Small-sized focal spots are essential in such techniques in order to reduce the resultant geometrical unsharpness. The x-ray intensity distribution of the focal spot is another crucial parameter for such a technique as it affects the mammographic resolution. In this study a Monte Carlo simulation model is utilized, in order to examine the effect of a wide range of focal spot sizes and three representative intensity distributions on spatial resolution under magnification. A thick sharp edge consisting of lead, non-transparent to x-rays was imaged under various conditions for this purpose, and the corresponding spatial resolution was calculated through the modulation transfer function (MTF). Results demonstrate that focal spots larger than 0.10 mm can mainly be used for low degrees of magnification, especially when combined with double peak Gaussian intensity distribution of the focal spot (sum of two single peak Gaussian distributions with different centers), as the resultant spatial resolution is not as high as the corresponding from smaller foci or uniform and single peak Gaussian distributions. Moreover, for the degrees of magnification usually utilized in clinical practice they do not reach the acceptable limit of 12 lp mm(-1). The replacement of the x-ray tube when the focal spot starts being destroyed is very crucial as the possible alteration of single peak Gaussian distribution to double peak Gaussian results in the degradation of spatial resolution. A focal spot of 0.10 mm or smaller, combined with single peak Gaussian intensity distribution, can be considered appropriate even for higher degrees of magnification and its use can contribute in the effort to optimize the magnification views in mammography.
authors.affiliation: University of Patras, School of Medicine, Department of Medical Physics, 265 00 Patras, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Koutalonis
authors.forename: H
authors.initials: H
authors.lastname: Delis
authors.forename: G
authors.initials: G
authors.lastname: Spyrou
authors.forename: L
authors.initials: L
authors.lastname: Costaridou
authors.forename: G
authors.initials: G
authors.lastname: Tzanakos
authors.forename: G
authors.initials: G
authors.lastname: Panayiotakis
mesh_terms: D016477:Artifacts; D008327:Mammography / Q000379:methods*; D009010:Monte Carlo Method; D011858:Radiographic Magnification / Q000379:methods*; D015203:Reproducibility of Results