title: C-ME: a 3D community-based, real-time collaboration tool for scientific research and training.
abstract: The need for effective collaboration tools is growing as multidisciplinary proteome-wide projects and distributed research teams become more common. The resulting data is often quite disparate, stored in separate locations, and not contextually related. Collaborative Molecular Modeling Environment (C-ME) is an interactive community-based collaboration system that allows researchers to organize information, visualize data on a two-dimensional (2-D) or three-dimensional (3-D) basis, and share and manage that information with collaborators in real time. C-ME stores the information in industry-standard databases that are immediately accessible by appropriate permission within the computer network directory service or anonymously across the internet through the C-ME application or through a web browser. The system addresses two important aspects of collaboration: context and information management. C-ME allows a researcher to use a 3-D atomic structure model or a 2-D image as a contextual basis on which to attach and share annotations to specific atoms or molecules or to specific regions of a 2-D image. These annotations provide additional information about the atomic structure or image data that can then be evaluated, amended or added to by other project members.
authors.affiliation: Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA.
authors.forename: Anand
authors.initials: A
authors.lastname: Kolatkar
authors.forename: Kevin
authors.initials: K
authors.lastname: Kennedy
authors.forename: Dan
authors.initials: D
authors.lastname: Halabuk
authors.forename: Josh
authors.initials: J
authors.lastname: Kunken
authors.forename: Dena
authors.initials: D
authors.lastname: Marrinucci
authors.forename: Kelly
authors.initials: K
authors.lastname: Bethel
authors.forename: Rodney
authors.initials: R
authors.lastname: Guzman
authors.forename: Tim
authors.initials: T
authors.lastname: Huckaby
authors.forename: Peter
authors.initials: P
authors.lastname: Kuhn
mesh_terms: D003195:Computer Communication Networks; D003196:Computer Graphics; D003299:Cooperative Behavior; D016208:Databases, Factual; D021621:Imaging, Three-Dimensional; D016247:Information Storage and Retrieval; D020407:Internet; D008958:Models, Molecular; D014584:User-Computer Interface