Do stem cells exist in the adult kidney?
Adult stem cells exist in many organs and play a critical role in normal cell turnover and the response to injury. The existence of adult stem cells in the mammalian kidney remains controversial. Kidney stem cells have been isolated and characterized by many groups, often with discrepant results. This article will review the current state of knowledge regarding adult kidney stem cells and discuss future directions for kidney stem cell research.
Gupta
Sandeep
S
Department of Medicine and Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA. gupta024@umn.edu
Rosenberg
Mark E
ME
D058186:Acute Kidney Injury / Q000473:pathology; D000328:Adult; D053687:Adult Stem Cells / Q000166:cytology*; D000818:Animals; D015415:Biomarkers / Q000032:analysis; D002478:Cells, Cultured; D006801:Humans; D007668:Kidney / Q000166:cytology*; D012038:Regeneration / Q000502:physiology
D015415:Biomarkers