title: Autoimmunity and celiac disease.
abstract: In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions. We review the most recent studies on CD pathogenesis and the possibilities to modulate immune dysfunction in CD.
authors.affiliation: Institute of Food Sciences of CNR, Avellino, Italy.
authors.forename: Carmen
authors.initials: C
authors.lastname: Gianfrani
authors.forename: Riccardo
authors.initials: R
authors.lastname: Troncone
authors.forename: Antonio
authors.initials: A
authors.lastname: La Cava
mesh_terms: D000595:Amino Acid Sequence; D015551:Autoimmunity / Q000276:immunology*; D002446:Celiac Disease / Q000188:drug therapy / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D004847:Epithelial Cells / Q000276:immunology / Q000473:pathology; D019204:GTP-Binding Proteins; D005983:Glutens / Q000737:chemistry / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D008969:Molecular Sequence Data; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011503:Transglutaminases / Q000276:immunology
chemical_list: D005983:Glutens; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011503:Transglutaminases; D019204:GTP-Binding Proteins