title: Rhodium-catalyzed kinetic resolution of tertiary homoallyl alcohols via stereoselective carbon-carbon bond cleavage.
abstract: A nonenzymatic kinetic resolution of tertiary homoallyl alcohols has been developed through a rhodium-catalyzed retro-allylation reaction under simple conditions. Selectivity factors of up to 12 have been achieved by employing (R)-H8-binap as the ligand, and the reaction can be conducted on a preparative scale.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. shintani@kuchem.kyoto-u.ac.jp
authors.forename: Ryo
authors.initials: R
authors.lastname: Shintani
authors.forename: Keishi
authors.initials: K
authors.lastname: Takatsu
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D007700:Kinetics; D020005:Propanols / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D020005:Propanols; C006463:allyl alcohol; D002244:Carbon; D012238:Rhodium