title: [Advances in study on anti-tumor mechanism of andrographolide].
abstract: In recent years, more and more attention was payed to the study of andrographolide. Andrographolide has the extensive pharmacological actions, such as anti-tumor, dephlogisticate and antibiosis and anti-virus. It was dected that andrographolide had the action of anti-tumor in gastric cancer, liver cancer, lung cancer and breast cancer. The anti-tumor mechanism of andrographolide was versatile, for instance, andrographolide can induce the apoptosis of cancer cell, inhibit the cell cycle, and increase the antitumor activity of lymphocyte. The following review was about the recent progress of study on the anti-tumor mechanism of andrographolide.
authors.affiliation: School of Basic Courses of GuangDong Pharmaceutical University, Guangzhou 510006, China.
authors.forename: Cui-Ling
authors.initials: CL
authors.lastname: Qi
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Wang
authors.forename: Xin-Lei
authors.initials: XL
authors.lastname: Zhou
mesh_terms: D035685:Andrographis / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D004224:Diterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D009369:Neoplasms / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; C030419:andrographolide