[Study on the critical value of soluble transferring receptor assessing iron deficiency anemia in Chinese child-bearing women].
OBJECTIVE
To compare soluble transferring receptor (sTfR) levels between iron deficiency anemia and normal iron status in Chinese child-bearing women and study the critical value of sTfR assessing iron deficiency anemia.


METHODS
251 normal iron status and 224 iron deficiency anemia of child-bearing women were drawn from National Nutrition and Health Survey (2002) as control group and case group respectively. The sTfR levels of two groups were determinated by enzyme linked immunosorbent assay (ELISA) and the critical value of sTfR assessing iron deficiency anemia was ascertained by ROC curve.


RESULTS
The levels of sTfR were (42.67 +/- 20.29) nmol/L and(21.08 +/- 6.70) nmol/L in case group and control group respectively and the former was higher than the latter significantly (P < 0.01). The optimal critical value of sTfR assessing iron deficiency anemia could be 25nmol/L.


CONCLUSIONS
The sTfR levels were more higher in iron deficiency anemia group of child-bearing women than those in normal iron status of child-bearing women. The critical value of sTfR assessing iron deficiency anemia may be more than 25nmol/L.
Li
Jianhong
J
Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Yang
Lichen
L
Piao
Jianhua
J
Yang
Xiaoguang
X
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000453:epidemiology; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D012372:ROC Curve; D011990:Receptors, Transferrin / Q000097:blood*; D055815:Young Adult
D011990:Receptors, Transferrin