Development of a 1H NMR structural-reporter-group concept for the primary structural characterisation of alpha-D-glucans.
An NMR study of proton chemical shift patterns of known linear alpha-D-glucopyranose di- and trisaccharide structures was carried out. Chemical shift patterns for (alpha1-->2)-, (alpha1-->3)-, (alpha1-->4)- and (alpha1-->6)-linked D-glucose residues were analysed and compared to literature data. Using these data, a 1H NMR structural-reporter-group concept was formulated to function as a tool in the structural analysis of alpha-D-glucans.
van Leeuwen
Sander S
SS
Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Leeflang
Bas R
BR
Gerwig
Gerrit J
GJ
Kamerling
Johannis P
JP
D004186:Disaccharidases / Q000737:chemistry; D005936:Glucans / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D014312:Trisaccharides / Q000737:chemistry
D005936:Glucans; D014312:Trisaccharides; D004186:Disaccharidases; D005947:Glucose