[Effect of nano-hydroxyapatite to glass ionomer cement].
OBJECTIVE
To investigate the mechanical character, microleakage and mineralizing potential of nano-hydroxyapatite (nano-HAP)-added glass ionomer cement(GIC).


METHODS
8% nano-HAP were incorporated into GIC as composite, and pure GIC as control. Both types of material were used to make 20 cylinders respectively in order to detect three-point flexural strength and compressive strength. Class V cavities were prepared in 120 molars extracted for orthodontic treatment, then were filled by two kinds of material. The microleakage at the composite-dentine interface was observed with confocal laser scanning microscope (CLSM) after stained with 1% rhodamin-B-isothiocyanate for 24 hours. Class V cavities were prepared in the molars of 4 healthy dogs, filled with composite, and the same molars in the other side were filled with GIC as control. The teeth were extracted to observe the mineralizing property with polarimetric microscope in 8 weeks after filling.


RESULTS
Three-point flexural strength and compressive of nano-HAP-added GIC were increased compared with pure GIC (P < 0.001, P < 0.05). The nanoleakages and microleakages appeared at the material-dentine interface in the two groups, but there were more microleakages in control group than in experiment group (P = 0.004). New crystals of hydroxyapatite were formed into a new mineralizing zone at the interface of tooth and nano-HAP-added GIC, while there was no hydroxyapatite crystals formed at the interface of tooth and pure GIC.


CONCLUSIONS
8% nano-HAP-added GIC can tightly fill tooth and have mineralizing potential, and can be used as liner or filling material for prevention.
Mu
Ya-Bing
YB
Dept of Conservative Dentistry, School of Stomatology, Jilin University, Changchun 130041, China.
Zang
Guang-Xiang
GX
Sun
Hong-Chen
HC
Wang
Cheng-Kun
CK
D000818:Animals; D003804:Dentin; D004285:Dogs; D017886:Durapatite; D005899:Glass Ionomer Cements
D005899:Glass Ionomer Cements; D017886:Durapatite