Autism in adults with severe intellectual disability: an empirical study of symptom presentation.
BACKGROUND
Autism is one of the most intriguing and highly studied conditions in the field of mental health. However, most research has been carried out with young children to the exclusion of adults, particularly adults with intellectual disability (ID). The present study represents a first attempt to describe symptom patterns of autism for adults with severe ID.


METHODS
Fifty-seven adults with ID who met DSM-IV-TR and ICD-10 diagnostic criteria for autism were compared to 57 matched controls with ID only (no Axis I diagnosis).


RESULTS
Marked differences were noted in a range of symptoms, particularly with respect to impairments in social interaction and restricted or repetitive behaviours and interests. These items were able to predict the presence or absence of autism at a high rate of diagnostic accuracy.


CONCLUSIONS
Based on these findings, it appears that adults with ID and autism evince a distinct pattern of impairment when compared to controls with ID alone.
Matson
Johnny L
JL
Department of Psychology, Louisiana State University, Baton Rouge, LA 70803, USA. johnmatson@aol.com
Wilkins
Jonathan
J
Ancona
Martin
M
D000328:Adult; D000368:Aged; D020817:Asperger Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D001321:Autistic Disorder / Q000175:diagnosis* / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis* / Q000453:epidemiology; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D018187:Personal Construct Theory; D012920:Social Behavior Disorders / Q000175:diagnosis* / Q000453:epidemiology; D012951:Socialization; D013239:Stereotyped Behavior