PGEToolbox: A Matlab toolbox for population genetics and evolution.
Assessing genetic diversity within populations is vital for understanding the nature of evolutionary processes at the molecular level. PGEToolbox is a Matlab-based open-sourced software package for data analysis in population genetics. The main features of this software are as follows: 1) capability for handling both DNA sequence polymorphisms and single nucleotide polymorphisms (SNPs), which include genotype and haplotype data; 2) exhaustive population genetic analyses and neutrality tests based on the coalescent theory; 3) extendibility and scalability for complex and large genome-wide datasets; 4) simple yet effective graphic user interfaces and sophisticated visualization of data and results. For academic uses, PGEToolbox is available free of charge at http://bioinformatics.org/pgetoolbox.
Cai
James J
JJ
Department of Biology, Stanford University, 371 Serra Mall, Stanford, CA 94305, USA. jamescai@stanford.edu
D000818:Animals; D019143:Evolution, Molecular; D005828:Genetics, Population / Q000379:methods*; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D012984:Software