A facile one-pot preparation of potassium hydroxyaryl- and (hydroxyalkyl)aryltrifluoroborates.
Potassium hydroxyaryl- and (hydroxyalkyl)aryltrifluoroborates have been prepared in a simple one-pot process from the corresponding hydroxy-substituted aryl halides in 51-98% yields through an in situ protection of the free hydroxyl group with t-BuLi. Also, we successfully performed a microwave-promoted Suzuki-Miyaura cross-coupling reaction of these substrates with aryl- and alkenyl bromides in the presence of 0.5 mol % of Pd(OAc)2 catalyst without ligands.
Park
Young Hee
YH
Korea Institute of Science and Technology, 290 Daejeon-dong, Gangneung 210-340, Korea.
Ahn
Hong Ryul
HR
Canturk
Belgin
B
Jeon
Sang Il
SI
Lee
Seokjoon
S
Kang
Heonjoong
H
Molander
Gary A
GA
Ham
Jungyeob
J
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D011188:Potassium / Q000737:chemistry*
D001897:Boronic Acids; D011188:Potassium