Nevirapine-induced Stevens-Johnson syndrome in a pediatric patient.
Nevirapine is a non-nucleoside reverse transcriptase inhibitor commonly used in human immunodeficiency virus-1 multidrug regimens and associated with life-threatening cutaneous reactions. Here, we report the successful use of intravenous immunoglobulin in a pediatric patient with Stevens-Johnson syndrome and highlight the risk of nevirapine usage in human immunodeficiency virus postexposure prophylaxis.
Mason
Ashley R
AR
Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Cortes
Gil Y
GY
Pollack
Ross B
RB
D000293:Adolescent; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006679:HIV Seropositivity; D006801:Humans; D019829:Nevirapine / Q000009:adverse effects* / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy
D019380:Anti-HIV Agents; D019829:Nevirapine