title: An approach to the core skeleton of lancifodilactone F.
abstract: Two cycloaddition reactions were utilized for the construction of the 5,6,7-tricyclic skeleton of lancifodilactone F and buxapentalactone. A [2+2] ketene cycloaddition reaction was first used to set their adjacent all-carbon quaternary centers at the 5,6-ring junction. An arene-olefin meta-photocycloaddition reaction was then used to install the 6- and 7-membered rings concurrently.
authors.affiliation: Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA.
authors.forename: Qiaoling
authors.initials: Q
authors.lastname: Wang
authors.forename: Chuo
authors.initials: C
authors.lastname: Chen
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D014315:Triterpenes; C506846:lancifodilactone F