New anti-inflammatory steroids from the Formosan soft coral Clavularia viridis.
Four new steroids, stoloniferones R-T (1-3), and (25S)-24-methylenecholestane-3 beta,5 alpha,6 beta-triol-26-acetate (4) were isolated from the methylene chloride solubles of the soft coral Clavularia viridis. The structures of the metabolites were elucidated by extensive spectral analysis and their anti-inflammatory activity was measured in vitro.
Chang
Chin-Hsiang
CH
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, ROC.
Wen
Zhi-Hong
ZH
Wang
Shang-Kwei
SK
Duh
Chang-Yih
CY
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000893:Anti-Inflammatory Agents / Q000737:chemistry*; D006888:Hydroxycholesterols / Q000737:chemistry; D013256:Steroids / Q000737:chemistry*
D000893:Anti-Inflammatory Agents; D006888:Hydroxycholesterols; D013256:Steroids