title: Persistent pupillary membranes in 3 siblings.
abstract: We report 3 siblings from a nonconsanguineous white family with bilateral persistent pupillary membranes with dissimilar forms of severity. Two of the patients required no treatment; 1 was treated surgically for occlusion of the pupillary axis and moderate visual acuity decrease. Anterior segment examination was otherwise normal in the siblings. Although persistent pupillary membranes are usually sporadic, cases in which they are associated with other anterior chamber abnormalities might be inherited autosomal dominant. To our knowledge, this is the first report of a familial isolated persistent papillary membrane case with no other anterior chamber abnormality.
authors.affiliation: Mersin University School of Medicine, Mersin, Turkey. docayc@yahoo.com
authors.forename: Ayça
authors.initials: A
authors.lastname: Sari
authors.forename: Ufuk
authors.initials: U
authors.lastname: Adigüzel
authors.forename: Münevver
authors.initials: M
authors.lastname: Yeşilli
authors.forename: Ozlem
authors.initials: O
authors.lastname: Aydin
authors.forename: Ozay
authors.initials: O
authors.lastname: Oz
mesh_terms: D002648:Child; D002675:Child, Preschool; D005124:Eye Abnormalities / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D005260:Female; D006801:Humans; D007498:Iris / Q000002:abnormalities*; D008297:Male; D008566:Membranes / Q000473:pathology; D008648:Mesoderm / Q000196:embryology; D010857:Pigment Epithelium of Eye / Q000473:pathology; D011681:Pupil Disorders / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D035781:Siblings