A combinatorial approach to 2,4,6-trisubstituted triazines with potent antimalarial activity: combining conventional synthesis and microwave-assistance.
Melato
Sergio
S
Institute of Molecular Science and Technology, CNR via G. Venezian 21, 20133 Milano, Italy.
Prosperi
Davide
D
Coghi
Paolo
P
Basilico
Nicoletta
N
Monti
Diego
D
D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis / Q000494:pharmacology* / Q000528:radiation effects; D002460:Cell Line; D020650:Combinatorial Chemistry Techniques; D042783:Endothelial Cells / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D008872:Microwaves; D015394:Molecular Structure; D021261:Parasitic Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014227:Triazines / Q000138:chemical synthesis / Q000494:pharmacology* / Q000528:radiation effects
D000962:Antimalarials; D014227:Triazines