Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress.
Modified haemoglobin levels were quantified in 21 Type 1 and 21 Type 2 diabetic patients and two groups of 17 non-diabetic subjects. Glycated haemoglobin levels were increased in diabetes but glutathionyl haemoglobin (HbSSG) levels did not differ between groups, nor by complications; nor correlate with haemoglobin glycation or vascular risk factors.
Hoffmann
Peter
P
St. Vincent's Institute of Medical Research, Fitzroy, Melbourne, Australia. Peter.Hoffmann@adelaide.edu.au
Woon
Jade
J
Rowley
Kevin G
KG
Karschimkus
Connie
C
Nelson
Craig L
CL
Dragicevic
George
G
O'Neal
David
D
Wilson
Andrew
A
Croft
Kevin D
KD
Mori
Trevor A
TA
Kemp
Bruce E
BE
Best
James D
JD
Jenkins
Alicia J
AJ
D001786:Blood Glucose / Q000378:metabolism*; D048909:Diabetes Complications / Q000097:blood*; D003920:Diabetes Mellitus / Q000097:blood*; D050171:Dyslipidemias / Q000097:blood*; D005978:Glutathione / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000097:blood*; D018384:Oxidative Stress
D001786:Blood Glucose; D006454:Hemoglobins; C404464:glutathionyl hemoglobin; D005978:Glutathione