title: Clostridium difficile: the increasingly difficult pathogen.
abstract: The epidemiology of Clostridium difficile infection is changing as a result of the epidemic spread of the hypervirulent North American Pulsefield type 1 strain. Clinicians are likely to encounter this disease more frequently than ever in their practice, and should be familiar with the updates in its diagnosis and treatment.
authors.forename: Aurora
authors.initials: A
authors.lastname: Pop-Vicas
authors.forename: Marguerite A
authors.initials: MA
authors.lastname: Neill
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016360:Clostridioides difficile / Q000145:classification / Q000472:pathogenicity*; D003015:Clostridium Infections / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents