title: Facile and highly stereoselective one-pot synthesis of either (E)- or (Z)-nitro alkenes.
abstract: Aliphatic aldehydes were reacted with nitro alkanes in the presence of catalytic amounts of piperidine over 4 A molecular sieves. Simply by changing reaction conditions (solvent and temperature) it is possible to control the stereochemical outcome of the reactions, obtaining pure (E)- and (Z)-nitro alkenes in high to excellent yields. The role of molecular sieves on the stereochemical control seems crucial in addition to that of piperidine, especially for the synthesis of the Z isomer.
authors.affiliation: Dipartimento di Chimica, Università degli Studi La Sapienza, P.le Aldo Moro 2, I-00185 Roma, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Fioravanti
authors.forename: Lucio
authors.initials: L
authors.lastname: Pellacani
authors.forename: Paolo A
authors.initials: PA
authors.lastname: Tardella
authors.forename: Maria Cecilia
authors.initials: MC
authors.lastname: Vergari