title: A novel programmable pulse generator with nanosecond resolution for pulsed electron paramagnetic resonance applications.
abstract: A pulse programmer with nanosecond time resolution needed for time-domain electron paramagnetic resonance (EPR) spectroscopic applications is described. This unit uses commercially available timing and input-output port modules and control software developed in our laboratory. The pulse programmer is operated through a personal computer front panel graphic user interface (GUI) inputs to control pulse widths, delays, and the associated acquisition trigger timings. Based on these parameters, all other associated gate and trigger timings are internally generated automatically without the need to enter them explicitly. The excitation pulse widths were of nanosecond resolution while all other gate pulses can be incremented in steps of 20 ns without compromising spectrometer performance. In the current configuration, the pulse programmer permits generation of a single pulse or multiple pulse sequences for EPR imaging with minimal data entry via the front panel GUI.
authors.affiliation: Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.
authors.forename: N
authors.initials: N
authors.lastname: Devasahayam
authors.forename: S
authors.initials: S
authors.lastname: Subramanian
authors.forename: M C
authors.initials: MC
authors.lastname: Krishna
mesh_terms: D004578:Electron Spin Resonance Spectroscopy / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008838:Microcomputers; D036103:Nanotechnology / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*