title: [Loss of metastatic deposits in breast sentinel lymph nodes during intra-operative frozen section analysis].
abstract: The intraoperative evaluation of sentinel lymph nodes is an ongoing debated issue. In this review we discuss different approaches to sentinel lymph node processing in an intra operative setting and in the consecutive embedding in paraffin. We propose a method, which uses routine intra operative examination of lymph nodes with stereo microscopy with selected frozen section analysis. We demonstrate preliminary data on a larger patient collective along with data on a control group. We could show in our study that a higher rate of metastates can be achieved avoiding intra operative frozen sections on grossly inconspicuous sentinel lymph nodes.
authors.affiliation: Institut für Klinische Pathologie, UniversitätsSpital Zürich.
authors.forename: Z
authors.initials: Z
authors.lastname: Varga
authors.forename: C
authors.initials: C
authors.lastname: Rageth
authors.forename: E
authors.initials: E
authors.lastname: Saurenmann
authors.forename: C
authors.initials: C
authors.lastname: Honegger
authors.forename: S
authors.initials: S
authors.lastname: von Orelli
authors.forename: M
authors.initials: M
authors.lastname: Fehr
authors.forename: D
authors.initials: D
authors.lastname: Fink
authors.forename: B
authors.initials: B
authors.lastname: Seifert
authors.forename: H
authors.initials: H
authors.lastname: Moch
authors.forename: R
authors.initials: R
authors.lastname: Caduff
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D016343:Monitoring, Intraoperative; D009362:Neoplasm Metastasis / Q000473:pathology*; D021701:Sentinel Lymph Node Biopsy