title: Primary laryngeal natural killer/T-cell lymphoma--report of a rare case.
abstract: BACKGROUND
  Natural killer (NK)/T-cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described.
  
  
  RESULTS
  A 73-year-old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T-cell lymphoma. This patient died of the disease despite the use of chemotherapy.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the second case of primary laryngeal NK/T-cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor-like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations.
authors.affiliation: Department of Otolaryngology, Hitachi General Hospital, Ibaraki, Japan. hiroko.monobe.rw@hitachi.com
authors.forename: Hiroko
authors.initials: H
authors.lastname: Monobe
authors.forename: Masato
authors.initials: M
authors.lastname: Nakashima
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Tominaga
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D007694:Killer Cells, Natural; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male