Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery.
Meyer
Martin
M
Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, Germany.
Philipp
Alexander
A
Oskuee
Reza
R
Schmidt
Claudia
C
Wagner
Ernst
E
D000818:Animals; D002460:Cell Line; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D011992:Endosomes / Q000187:drug effects / Q000378:metabolism; D018014:Gene Transfer Techniques; D006863:Hydrogen-Ion Concentration; D008299:Maleic Anhydrides / Q000737:chemistry; D008555:Melitten / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D009447:Neuroblastoma; D011073:Polyamines / Q000737:chemistry*; D000071228:Polyelectrolytes; D011092:Polyethylene Glycols / Q000737:chemistry*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000737:chemistry* / Q000494:pharmacology
D004337:Drug Carriers; D008299:Maleic Anhydrides; D008555:Melitten; D011073:Polyamines; D000071228:Polyelectrolytes; D011092:Polyethylene Glycols; D034741:RNA, Small Interfering