title: Dynamic contour tonometry in comparison to intracameral IOP measurements.
abstract: OBJECTIVE
  The purpose of the study was to examine the effect of central corneal thickness (CCT), corneal curvature, astigmatism, axial length (AL), and age on measurements with the Pascal Dynamic Contour Tonometer (DCT).
  
  
  METHODS
  In a prospective clinical trial 75 eyes of 75 patients undergoing phacoemulsification were examined. Before phacoemulsification, the anterior chamber was cannulated at the temporal corneal limbus. In a closed system the IOP was directly set to 15, 20, or 35 mm Hg with a manometric water column. IOP measurements taken by DCT were compared to intracameral measurements with a precision reference pressure sensor.
  
  
  RESULTS
  Measurements from 60 patients were suitable for statistical analysis. At IOP of 15 mm Hg, the mean difference between IOP measured by DCT and intracameral IOP was -0.02 +/- 1.32 mm Hg; at 20 mm Hg it was -0.2 +/- 1.44 mm Hg and at 35 mm Hg, -0.84 +/- 1.90 mm Hg. The concordance coefficient according to Lin was 0.9763, showing good agreement between DCT- and intracamerally measured IOP. There was a statistically significant correlation between the difference in IOP measured by DCT minus intracameral IOP and CCT (P = 0.0291, R2 = 0.00012). All other parameters had no statistically significant effect on the difference between DCT and intracameral IOP (corneal curvature, P = 0.6094, R2 = 0.00367; age, P = 0.9198, R2 = 0.000003; astigmatism, P = 0.1564, R2 = 0.08497; and axial length, P = 0.9484, R2 = 0.00008).
  
  
  CONCLUSIONS
  Measurements with the DCT showed good concordance with intracameral IOP. CCT exerted a statistically significant but clinically irrelevant effect on measurements with the DCT.
authors.affiliation: Department of Ophthalmology, University of Dresden, Dresden, Germany. boehm@uniklinkum-dresden.de
authors.forename: Andreas G
authors.initials: AG
authors.lastname: Boehm
authors.forename: Anja
authors.initials: A
authors.lastname: Weber
authors.forename: Lutz E
authors.initials: LE
authors.lastname: Pillunat
authors.forename: Rainer
authors.initials: R
authors.lastname: Koch
authors.forename: Eberhard
authors.initials: E
authors.lastname: Spoerl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000867:Anterior Chamber / Q000502:physiology*; D001251:Astigmatism / Q000503:physiopathology; D002404:Catheterization; D003315:Cornea / Q000033:anatomy & histology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D018918:Phacoemulsification; D011446:Prospective Studies; D015203:Reproducibility of Results; D014065:Tonometry, Ocular / Q000379:methods*