Role of intravenous fluorescein angiography in early detection and regression of retinopathy of prematurity.
OBJECTIVE
To study the role of intravenous fluorescein angiography in early detection and regression of retinopathy of prematurity.


METHODS
The Retcam 120 (Massie Research Laboratories, Dublin, CA) was used to perform intravenous fluorescein angiography in 40 eyes of 20 children diagnosed as having treatable retinopathy of prematurity as per Early Treatment for Retinopathy of Prematurity Cooperative Group guidelines and treated with laser photocoagulation.


RESULTS
Fluorescein angiography enabled easy visualization of the retinal vasculature and helped to identify early flat neovascularization in zone 1/2 retinopathy of prematurity, detect previously missed areas of active retinopathy of prematurity in the peripheral retina, and identify skip areas following laser photocoagulation, which resulted in good management outcomes. There were no side effects related to sodium fluorescein or the procedure.


CONCLUSIONS
Retcam-assisted intravenous fluorescein angiography is safe and helps in the early diagnosis, prompt management, and complete regression of retinopathy of prematurity.
Azad
Rajvardhan
R
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Chandra
Parijat
P
Khan
Mansoor Ali
MA
Darswal
Aparna
A
D005260:Female; D019793:Fluorescein / Q000008:administration & dosage; D005451:Fluorescein Angiography / Q000379:methods*; D005456:Fluorescent Dyes / Q000008:administration & dosage; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007275:Injections, Intravenous; D017075:Laser Coagulation; D008297:Male; D011446:Prospective Studies; D012171:Retinal Vessels / Q000473:pathology*; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000601:surgery
D005456:Fluorescent Dyes; D019793:Fluorescein