[Reactive oxygen species and vascular hyporeactivity in septic shock. Part I--reactive oxygen species and vascular hyporeactivity].
Reactive oxygen species (ROS) are formed as a result of physiologic cellular metabolism and although they are essential for signalization they also, when produced in excess, contribute to the pathogenesis of many diseases. This paper is an attempt to summarize the role of ROS in the development of vascular hyporeactivity. At the beginning the sources of ROS are discussed. The next part deals with the mechanisms leading to vascular hyporeactivity.
Gendzwiłł
Anna
A
Akademia Medyczna w Gdańsku, Katedra i Zakład Farmakologii. Matylda1908@op.pl
D004730:Endothelium, Vascular / Q000378:metabolism*; D006439:Hemodynamics; D006801:Humans; D010100:Oxygen / Q000378:metabolism* / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D012772:Shock, Septic / Q000378:metabolism*
D017382:Reactive Oxygen Species; D010100:Oxygen