title: Genes and structure of selected cytokines involved in pathogenesis of psoriasis.
abstract: Psoriasis is a common skin disease involving 1-4% of human population worldwide, of strong genetic background. The following cytokines are directly involved in psoriasis: TNF, IL-1, IL-2, IL-6, IL-7, IL-8, IL-15, IL-18, IL-19, IL-20, IL-23 whereas IL-4, IL-10, IL-12 as well as IL-11, IL-17 and IFN-gamma are rather indirectly engaged. This work is a review of some genetic factors and structure of selected cytokines and receptors and their genes location.
authors.affiliation: Department of Dermatology, Medical University of Lublin, Poland.
authors.forename: Aldona
authors.initials: A
authors.lastname: Pietrzak
authors.forename: Anna
authors.initials: A
authors.lastname: Zalewska
authors.forename: Grazyna
authors.initials: G
authors.lastname: Chodorowska
authors.forename: Piotr
authors.initials: P
authors.lastname: Nockowski
authors.forename: Anna
authors.initials: A
authors.lastname: Michalak-Stoma
authors.forename: Paweł
authors.initials: P
authors.lastname: Osemlak
authors.forename: Dorota
authors.initials: D
authors.lastname: Krasowska
mesh_terms: D000818:Animals; D016207:Cytokines / Q000737:chemistry* / Q000235:genetics*; D006801:Humans; D011565:Psoriasis / Q000235:genetics* / Q000473:pathology*; D018121:Receptors, Cytokine / Q000737:chemistry / Q000235:genetics
chemical_list: D016207:Cytokines; D018121:Receptors, Cytokine