title: Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype.
abstract: Inflammatory breast cancer (IBC) is the most aggressive and distinct form of primary breast cancer with a peculiar clinical presentation and dismal clinical outcome. This review addresses the pathologic aspects of this entity and discusses the molecular alterations involved in the highly malignant phenotype of IBC.
authors.affiliation: Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. yungong@mdanderson.org
authors.forename: Yun
authors.initials: Y
authors.lastname: Gong
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D001943:Breast Neoplasms / Q000235:genetics / Q000276:immunology* / Q000473:pathology*; D002277:Carcinoma / Q000150:complications / Q000209:etiology* / Q000235:genetics / Q000473:pathology*; D015815:Cell Adhesion Molecules / Q000502:physiology; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007249:Inflammation / Q000235:genetics / Q000473:pathology*; D042583:Lymphangiogenesis / Q000502:physiology; D009361:Neoplasm Invasiveness; D009389:Neovascularization, Pathologic / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D015815:Cell Adhesion Molecules