[Genetic risks of intracytoplasmic sperm injection for male infertility].
Recently, intracytoplasmic sperm injection (ICSI) has been extremely successful in the treatment of male infertility. However, the consequent transmission of sperm cytogenetic defects and genetic defects to the offspring has aroused considerable concern. Among infertile men, those with severe spermatogenic defects, including oligozoospermia and azoospermia, are mostly the subjects for ICSI. Therefore it is very important to obtain cytogenetic and chromosomal information on these infertile patients and prevent the inheritance of these genetic defects. This review offers an analysis on the genetic defects among infertile men.
Shao
Fa-Ming
FM
Department of Urology, Affiliated Hospital of Ningbo University School of Medicine, Ningbo, Zhejiang 315020, China. ybchenjian@126.com
Zhu
Xiao-Bin
XB
Li
Zheng
Z
D041322:Chromosomes, Human, Y / Q000235:genetics; D056426:Genetic Loci; D006801:Humans; D007248:Infertility, Male / Q000235:genetics* / Q000628:therapy*; D008297:Male; D029589:Seminal Plasma Proteins / Q000235:genetics*; D020554:Sperm Injections, Intracytoplasmic
D029589:Seminal Plasma Proteins