[Quantitative determination of adrenaline by visible spectrophotometric method].
A sensible and rapid spectrophotometric assay for adrenaline was developed.


METHODS
The method is based on the reaction with ammonium molybdate and sodium nitrite in acid medium.


RESULTS
The obtained compound is stable, soluble in water and has the absorbtion maximum at 405 nm. Beer's law is valid within a concentration range of 20-160 microg/mL. The validity of the method was tested by statistical analysis of the experimental data using the linearity, the scale's calibration factor, the detection limit, the quantification limit and the precision.


CONCLUSIONS
A new method for the assay of adrenaline in pharmaceutical products has been developed.
Bibire
Nela
N
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Farmacie, Disciplina de Chimie Analitică.
Christopoulos
L
L
Apostu
M
M
Dorneanu
V
V
D000322:Adrenergic Agonists / Q000032:analysis*; D004837:Epinephrine / Q000032:analysis*; D006801:Humans; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*
D000322:Adrenergic Agonists; D004837:Epinephrine