title: The probable associations for corticocapsular adhesions in patients undergoing cataract surgery: a clinic-based observational study.
abstract: BACKGROUND
  Corticocapsular adhesions (CCA) are frequently seen between lens capsule and adjacent cortical layer. During cataract surgery, in the presence of CCA, excessive efforts to rotate the nucleus can result in zonular damage. To reduce morbidity, identification of associations with CCA can be helpful in appropriately modifying the surgical procedure.
  
  
  OBJECTIVE
  To investigate probable associations with CCA in patients undergoing cataract surgery.
  
  
  METHODS
  Iladevi Cataract and IOL research center. Case-control study.
  
  
  METHODS
  A single eye of 600 patients, 200 patients with CCA (cases) and 400 patients without CCA (controls) were considered. A CCA diagnosis was based on: (i) preoperative presence of CCA on slit-lamp examination with visualization of furry surface of cortex during surgery; (ii) preoperative absence of CCA on slit-lamp examination but intraoperative visualization of furry surface of cortex. Variables such as age, gender, type of cataract, grade of cataract, high myopia, diabetes mellitus and hypertension were studied.
  
  
  METHODS
  Multivariate logistic regression was done. Results were presented as odds ratio (OR) with 95% CI.
  
  
  RESULTS
  Mean age was 64.71 +/- 9.10 years in cases and 59.27 +/- 8.79 years in controls. Presence of CCA increased with age from 22% (n = 59) in 45 to 49 years to 70% (n = 110) in 70 to 79 years. An increase in age was associated with CCA by 3.3% (OR = 3.3%, P = 0.028). The odds of CCA for females were 83% higher ( P = 0.027). Presence of anterior cortical cataract increased odds of CCA by 9.5 times ( P = 0.001), while posterior cortical cataract increased odds by 3.3 times ( P = 0.001).
  
  
  CONCLUSIONS
  Corticocapsular adhesions were strongly associated with cortical cataracts, increased age and female gender.
authors.affiliation: Iladevi Cataract and IOL Research Center, Raghudeep Eye Clinic, Memnagar, Ahmedabad - 380 052, Gujarat, India. icirc@abhayvasavada.com
authors.forename: Abhay R
authors.initials: AR
authors.lastname: Vasavada
authors.forename: Shetal M
authors.initials: SM
authors.lastname: Raj
authors.forename: M R
authors.initials: MR
authors.lastname: Praveen
authors.forename: Viraj A
authors.initials: VA
authors.lastname: Vasavada
authors.forename: Vaishali A
authors.initials: VA
authors.lastname: Vasavada
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002386:Cataract / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D007904:Lens Cortex, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D012307:Risk Factors; D012737:Sex Factors; D000267:Tissue Adhesions