[Evidence-based medicine in urology].
The quality of a therapeutic trial depends on several parameters. The ideal trial in prostate cancer should be a high-quality trial on a well-defined and significant population. The method used to calculate the number of subjects necessary should appear in the study. There should be a single and significant evaluation criterion and follow-up should be long given the natural history of the disease. Intention to treat is also a quality terion. Finally, the therapeutic class effect does not exist; therefore, the efficacy of inoma any new drug must be proven.
Bergmann
J F
JF
Service de médecine interne A, hôpital Lariboisière, 2, rue Ambroise-Paré 75475 Paris Cedex 10, France. jf.bergmann@lrb.aphp.fr
D002986:Clinical Trials as Topic / Q000592:standards*; D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000628:therapy; D014572:Urology / Q000592:standards*