Drug-associated histiocytoid Sweet's syndrome: a true neutrophilic maturation arrest variant.
Histiocytoid Sweet's syndrome is a recently described entity which has clinical features identical to typical Sweet's syndrome but is distinguished by a dermal cellular infiltrate composed not of mature neutrophils but of immature granulocytes. Herein, we report a case of bone marrow granulocytic maturation arrest and a histological histiocytoid Sweet's-like reaction pattern following trimethoprim-sulfamethoxazole therapy.
Wu
Angela J
AJ
Department of Pathology, University of Michigan Medical Center, Ann Arbor, MI 48109-0602, USA.
Rodgers
Timothy
T
Fullen
Douglas R
DR
D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002454:Cell Differentiation; D005260:Female; D005434:Flow Cytometry; D015614:Histiocytosis / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D017403:In Situ Hybridization; D009504:Neutrophils / Q000166:cytology* / Q000473:pathology; D012852:Sinusitis / Q000188:drug therapy; D016463:Sweet Syndrome / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination