A squamous metaplasia in a gastric ulcer scar of the antrum.
An 81-year-old man presented with epigastric pain and weight loss for one month. He had a past history of pulmonary tuberculosis, 10 years ago. We performed a gastroscopy, which showed a linear depressed whitish gastric ulcer scar (0.8 cm in length) in the posterior wall of the prepyloric antrum. The result of biopsy was reported as squamous epithelium. Immunohistochemical staining using an antibody to high molecular weight cytokeratin (HMC) revealed positive staining in the squamous epithelium. Two years later, the lesion was followed up. The lesion remained at same site endoscopically, but no squamous epithelium could be seen microscopically.
Cho
Young-Seok
YS
Department of Internal Medicine Uijeongbu St. Mary's Hospital, 65-1 Geumo-dong, Uijeongbu 480-717, Korea.
Kim
Jin-Soo
JS
Kim
Hyung-Keun
HK
Ji
Jeong-Seon
JS
Kim
Byung-Wook
BW
Chae
Hiun-Suk
HS
Han
Sok-Won
SW
Choi
Kyu-Yong
KY
Chung
In-Sik
IS
D015746:Abdominal Pain; D000369:Aged, 80 and over; D001706:Biopsy; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007633:Keratins / Q000378:metabolism; D008297:Male; D008679:Metaplasia / Q000175:diagnosis*; D008970:Molecular Weight; D013276:Stomach Ulcer / Q000473:pathology*; D016896:Treatment Outcome; D014456:Ulcer / Q000473:pathology*
D007633:Keratins