title: Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units.
abstract: Resistance profiles were compared among 18 extended-spectrum-beta-lactamase-producing (ESBL) and 27 acquired AmpC beta-lactamase-producing Escherichia coli isolates collected from Canadian intensive care units from 2005 to 2006. ESBL-producing E. coli isolates were more likely to be gentamicin resistant (P < 0.03), fluoroquinolone resistant (P < 0.0001), and multidrug resistant (P < 0.0001) than AmpC-producing E. coli isolates.
authors.affiliation: Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, R3A 1R9, Manitoba, Canada. trishbaudry@hotmail.com
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Baudry
authors.forename: Kim
authors.initials: K
authors.lastname: Nichol
authors.forename: Melanie
authors.initials: M
authors.lastname: DeCorby
authors.forename: Laura
authors.initials: L
authors.lastname: Mataseje
authors.forename: Michael R
authors.initials: MR
authors.lastname: Mulvey
authors.forename: Daryl J
authors.initials: DJ
authors.lastname: Hoban
authors.forename: George G
authors.initials: GG
authors.lastname: Zhanel
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D002170:Canada; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology; D024841:Fluoroquinolones / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D024841:Fluoroquinolones; D005839:Gentamicins; C048795:AmpC beta-lactamases; D001618:beta-Lactamases