title: A randomized crossover trial of conservative snoring treatments: mandibular repositioning splint and nasal CPAP.
abstract: OBJECTIVE
  To compare the effectiveness of a mandibular repositioning splint (MRS) and nasal continuous positive airway pressure (CPAP) device as first-line treatments for disruptive snoring.
  
  
  METHODS
  Prospective randomized crossover trial.
  
  
  METHODS
  Twenty snorers received 3 months of treatment with both an MRS and nasal CPAP. Snoring Outcomes Survey (SOS), Snoring Bed Partner Survey, and Epworth questionnaires were completed serially. Changes in questionnaire scores were analyzed with a general linear statistical model and by analysis of variance.
  
  
  RESULTS
  There was a significant difference between the three preference outcomes for the mean SOS changes (P = 0.003). The mean SOS change was significantly greater for those who preferred MRS to CPAP (mean score difference, 27.15). Eight snorers chose final long-term MRS treatment, five chose nasal CPAP, and seven chose neither.
  
  
  CONCLUSIONS
  The majority of disruptive snorers can be managed effectively with conservative treatments and therefore avoid surgery.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Crosshouse Hospital, Kilmarnock, Scotland, UK. stuart@glasgow.org
authors.forename: Stuart
authors.initials: S
authors.lastname: Robertson
authors.forename: Maria
authors.initials: M
authors.lastname: Murray
authors.forename: David
authors.initials: D
authors.lastname: Young
authors.forename: Richard
authors.initials: R
authors.lastname: Pilley
authors.forename: John
authors.initials: J
authors.lastname: Dempster
mesh_terms: D045422:Continuous Positive Airway Pressure; D018592:Cross-Over Studies; D004867:Equipment Design; D006801:Humans; D008334:Mandible; D017090:Occlusal Splints; D011446:Prospective Studies; D012913:Snoring / Q000517:prevention & control*; D016896:Treatment Outcome