title: Human cathepsin D.
abstract: A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.
authors.affiliation: 3rd Department of Children's Diseases, Medical University, Bialystok, Poland. lukmin@mp.pl
authors.forename: Alina
authors.initials: A
authors.lastname: Minarowska
authors.forename: Marek
authors.initials: M
authors.lastname: Gacko
authors.forename: Alicja
authors.initials: A
authors.lastname: Karwowska
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Minarowski
mesh_terms: D000595:Amino Acid Sequence; D002402:Cathepsin D / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D011499:Protein Processing, Post-Translational; D013379:Substrate Specificity
chemical_list: D002402:Cathepsin D