Autoimmunity and glaucoma.
Elevated intraocular pressure does not explain glaucoma in all patients, but there is information that autoimmune mechanisms may be involved in this disorder. This review attempts to reveal the findings about specific changes in autoantibody profiles in glaucoma patients and their possible role in glaucoma. Considering that these changes in natural autoimmunity can be found consistently among different study populations, it might be a promising new tool for glaucoma detection.
Grus
Franz H
FH
Experimental Ophthalmology, Department of Ophthalmology, Johannes Gutenberg University, Mainz, Germany. grus@eye-research.org
Joachim
Stephanie C
SC
Wuenschig
Diana
D
Rieck
Jochen
J
Pfeiffer
Norbert
N
D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology; D015551:Autoimmunity / Q000502:physiology*; D005901:Glaucoma / Q000276:immunology*; D006801:Humans; D007429:Intraocular Pressure
D001323:Autoantibodies