Geographic linkage and variation in Cryptosporidium hominis.
UK Cryptosporidium hominis isolates have previously shown slight PCR fragment length polymorphism at multiple loci. To further investigate transmission, we conducted a case-control study and sequenced the GP60 locus from 115 isolates. Nine subtypes were identified; IbA10G2 predominated. Having a non-IbA10G2 subtype was significantly linked to recent travel outside Europe.
Chalmers
Rachel M
RM
National Public Health Service Microbiology, Swansea, Wales, UK. rachel.chalmers@nphs.wales.nhs.uk
Hadfield
Stephen J
SJ
Jackson
Colin J
CJ
Elwin
Kristin
K
Xiao
Lihua
L
Hunter
Paul
P
D000818:Animals; D003457:Cryptosporidiosis / Q000453:epidemiology* / Q000469:parasitology*; D003458:Cryptosporidium / Q000235:genetics*; D005060:Europe; D006801:Humans; D007630:Kenya; D009520:New Zealand; D010154:Pakistan; D014195:Travel; D014416:Tunisia; D014421:Turkey