[Human genome project: a federator program of genomic medicine].
The Human Genome Project improves our understanding of the molecular genetics basis of the inherited and complex diseases such as diabetes, schizophrenia, and cancer. Information from the human genome sequence is essential for several antenatal and neonatal screening programmes. The new genomic tools emerging from this project have revolutionized biology and medicine and have transformed our understanding of health and the provision of healthcare. Its implications pervade all areas of medicine, from disease prediction and prevention to the diagnosis and treatment of all forms of disease. Increasingly, it will be possible to drive predisposition testing into clinical practice, to develop new treatments or to adapt available treatments more specifically to an individual's genetic make-up. This genomic information should transform the traditional medications that are effective for every members of the population to personalized medicine and personalized therapy. The pharmacogenomics could give rise to a new generation of highly effective drugs that treat causes, not just symptoms.
Sfar
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Laboratoire d'immuno-oncologie moléculaire, faculté de médecine de Monastir, avenue Avicenne, Monastir, Tunisia. sfarsana@yahoo.fr
Chouchane
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D030342:Genetic Diseases, Inborn / Q000235:genetics* / Q000628:therapy; D020022:Genetic Predisposition to Disease; D005826:Genetics, Medical; D016045:Human Genome Project; D006801:Humans