Sclerosing pancreatitis presenting as a periampullary tumour.
BACKGROUND
Sclerosing lesions of the pancreatic duct are rare and may be secondary to primary sclerosing cholangitis (PSC) or the result of a primary sclerosing process (the recently described lymphoplasmacystic sclerosing pancreatitis, LSP). Occasionally this process may present as a mass lesion.


METHODS
A 21 -year-old man presented with abdominal pain and jaundice, giving a high index of suspicion for a periampullary malignancy. There were minimal symptoms suggestive of PSC. The resected head of the pancreas demonstrated changes of chronic pancreatitis with a fibro-inflammatory process of the pancreatic duct suggesting an underlying ductal sclerosing process.


CONCLUSIONS
Clinical presentation and imaging characteristics of PSC involving the pancreas are often misleading and may suggest a neoplasm as the underlying disorder. Conclusive diagnosis is usually not determined until after surgical intervention. Although racial differences in pancreatic duct involvement have been suggested, the underlying histopathology is the same as in PSC involving the biliary ducts.
Sahajpal
A K
AK
University of Toronto, Mount Sinai Hospital, Suite 1225, 600 University Avenue, Toronto, Ontario, M5G 1X5 Canada.
Vollmer
C M
CM
Pollett
A
A
Gallinger
S
S