Prevention of contrast-induced nephropathy with sodium bicarbonate: an evidence-based protocol.
Contrast-induced nephropathy has continued to plague interventional cardiology as an all-too-frequent complication of diagnostic and therapeutic procedures. We present an evidence-based protocol for prevention of this complication that uses infusion of NaHCO3 to effect urinary alkalinization and possibly decrease free-radical renal injury resulting from contrast exposure.
Merten
Gregory J
GJ
Division of Nephrology, Mayo Clinic, Rochester, Minnesota, USA.
Burgess
W Patrick
WP
Rittase
Robert A
RA
Kennedy
Thomas P
TP