title: One step cascade synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles.
abstract: A Lewis base-catalyzed three-component cascade reaction was developed for the synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles. More than 25 new (NH)-triazoles were prepared in good to excellent yields under mild conditions. The availability of the C-4 vinyl group allows easy conversion into other triazole derivatives.
authors.affiliation: C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.
authors.forename: Sujata
authors.initials: S
authors.lastname: Sengupta
authors.forename: Haifeng
authors.initials: H
authors.lastname: Duan
authors.forename: Weibing
authors.initials: W
authors.lastname: Lu
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Petersen
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi