title: Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of beta-glucuronides.
abstract: The glycosynthase derived from E. coli beta-glucuronidase catalyzes the glucuronylation of a range of primary, secondary, and aryl alcohols with moderate to excellent yields. The procedure provides an efficient, stereoselective, and scalable single-step synthesis of beta-glucuronides under mild conditions.
authors.affiliation: School of Chemistry, University of Sydney, NSW 2006, Australia.
authors.forename: Shane M
authors.initials: SM
authors.lastname: Wilkinson
authors.forename: Chu W
authors.initials: CW
authors.lastname: Liew
authors.forename: Joel P
authors.initials: JP
authors.lastname: Mackay
authors.forename: Hamzah M
authors.initials: HM
authors.lastname: Salleh
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Withers
authors.forename: Malcolm D
authors.initials: MD
authors.lastname: McLeod
mesh_terms: D004926:Escherichia coli / Q000201:enzymology*; D020719:Glucuronides / Q000096:biosynthesis*; D014453:Glucuronosyltransferase / Q000737:chemistry / Q000378:metabolism*; D015202:Protein Engineering
chemical_list: D020719:Glucuronides; D014453:Glucuronosyltransferase