title: Advances and challenges in the use of biomarkers in clinical trials.
authors.affiliation: Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.
authors.forename: Bruce
authors.initials: B
authors.lastname: Chabner
mesh_terms: D000970:Antineoplastic Agents / Q000191:economics / Q000627:therapeutic use; D054316:Biomarkers, Pharmacological / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002986:Clinical Trials as Topic / Q000379:methods; D015195:Drug Design; D006801:Humans; D007155:Immunologic Factors / Q000191:economics / Q000627:therapeutic use; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000970:Antineoplastic Agents; D054316:Biomarkers, Pharmacological; D014408:Biomarkers, Tumor; D007155:Immunologic Factors