Chronic hepatitis ameliorates anaemia in haemodialysis patients.
BACKGROUND
Study for influence of chronic hepatitis (CH) on anaemia in haemodialysis (HD) patients remains inconclusive. We aim to characterize the red cell status between CH and hepatitis-free groups among the HD population.


METHODS
We retrospectively analysed 80 chronic HD patients from Taipei Medical University Hospital with monthly sampled biochemical study between December 2004 and December 2005. Data classified according to the hepatitis-free, chronic hepatitis B and C groups were expressed as mean +/- standard deviation. Student's t-test and anova were used to determine the mean difference for continuous variables.


RESULTS
Age, Kt/V, systolic or diastolic blood pressure, body mass index, total cholesterol and triglyceride were not different between CH and hepatitis-free groups. HD duration (P = 0.0002), aspartate (P < 0.0001), alanine aminotransferase (P < 0.0001), alkaline phosphatase (P = 0.04), haemoglobin (P = 0.0066) and haematocrit (P = 0.002) were significantly more elevated in the CH group demanding less erythropoietin dose than in the hepatitis-free group.


CONCLUSIONS
Our study demonstrated that lessened anaemia was observed in CH, which demanded less erythropoietin dose.
Lin
Yi-Lung
YL
Department of Internal Medicine, Division of Nephrology, Taipei Medical University and Hospital, Taipei, Taiwan.
Lin
Chi-Wei
CW
Lee
Chieh-Hua
CH
Lai
I-Chun
IC
Chen
His-Hsien
HH
Chen
Tzen-Wen
TW
D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000740:Anemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000821:virology; D001219:Aspartate Aminotransferases / Q000097:blood; D004921:Erythropoietin / Q000008:administration & dosage*; D005260:Female; D006397:Hematinics / Q000008:administration & dosage*; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D019694:Hepatitis B, Chronic / Q000097:blood / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000097:blood / Q000150:complications*; D006801:Humans; D007275:Injections, Intravenous; D007674:Kidney Diseases / Q000097:blood / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D006435:Renal Dialysis; D012189:Retrospective Studies
D006397:Hematinics; D006454:Hemoglobins; D011994:Recombinant Proteins; D004921:Erythropoietin; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase