title: Automatic detection of immature platelets for decision making regarding platelet transfusion indications for pediatric patients.
abstract: Immature or reticulated platelets are known as a clinical marker of thrombopoiesis. Recently, an automatic method was established to detect reticulated platelets as immature platelet fraction (IPF) by means of hematology analyzer XE-2100. We assessed the effects of IPF detection after chemotherapy for various pediatric malignant disorders of 16 patients. Our results indicate that IPF should be considered a useful marker of imminent platelet recovery so that unnecessary platelet transfusion can be avoided.
authors.affiliation: Blood Transfusion Division, Kobe University Hospital, Chuo-ku, Kobe 650-0017, Japan. saigo@med.kobe-u.ac.jp
authors.forename: Katsuyasu
authors.initials: K
authors.lastname: Saigo
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Sakota
authors.forename: Yukako
authors.initials: Y
authors.lastname: Masuda
authors.forename: Kyoko
authors.initials: K
authors.lastname: Matsunaga
authors.forename: Mariko
authors.initials: M
authors.lastname: Takenokuchi
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Nishimura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Kosuke
authors.initials: K
authors.lastname: Sakurai
authors.forename: Makoto
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Tomoko
authors.initials: T
authors.lastname: Yanai
authors.forename: Akira
authors.initials: A
authors.lastname: Hayakawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeshima
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nomura
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Kubota
authors.forename: Shunichi
authors.initials: S
authors.lastname: Kumagai
mesh_terms: D000293:Adolescent; D001331:Automation; D001792:Blood Platelets / Q000166:cytology* / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004867:Equipment Design; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010976:Platelet Count; D017713:Platelet Transfusion / Q000379:methods*; D012016:Reference Values; D033581:Stem Cell Transplantation; D034061:Thrombopoiesis; D013997:Time Factors