title: Infectious arthritis as the single manifestation of sporotrichosis: serology from serum and synovial fluid samples as an aid to diagnosis.
abstract: Sporotrichosis is a generally cutaneous, granulomatous, chronic and benign infection. Less frequently the disease may affect the joints. Articular involvement is usually characterized by monoarthritis in the absence of systemic symptoms, generally preceded by skin lesions, and frequently affects immunosuppressed individuals. We describe here the case of a healthy patient presenting knee arthritis without skin lesions, diagnosed as sporotrichosis, and treated with oral itraconazole. Serology used in this case was an invaluable tool for the diagnosis of sporotrichosis arthritis lacking skin lesions.
authors.affiliation: Serviço de Dermatologia, Laboratório de Micologia, Hospital Universitário Pedro Ernesto, UERJ, Rio de Janeiro, Brazil. rosaneorofino@globo.com
authors.forename: Rosane Orofino
authors.initials: RO
authors.lastname: Costa
authors.forename: Karlos Celso
authors.initials: KC
authors.lastname: de Mesquita
authors.forename: Patrícia S
authors.initials: PS
authors.lastname: Damasco
authors.forename: Andréa Reis
authors.initials: AR
authors.lastname: Bernardes-Engemann
authors.forename: Claudia Maria P
authors.initials: CM
authors.lastname: Dias
authors.forename: Ione C
authors.initials: IC
authors.lastname: Silva
authors.forename: Leila M
authors.initials: LM
authors.lastname: Lopes-Bezerra
mesh_terms: D000369:Aged, 80 and over; D000908:Antibodies, Fungal / Q000032:analysis*; D000935:Antifungal Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D001182:Arthroscopy; D001706:Biopsy; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D007719:Knee Joint / Q000382:microbiology*; D013175:Sporothrix / Q000276:immunology / Q000302:isolation & purification*; D013174:Sporotrichosis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D013582:Synovial Fluid / Q000276:immunology / Q000382:microbiology
chemical_list: D000908:Antibodies, Fungal; D000935:Antifungal Agents; D017964:Itraconazole