title: [Hormone therapy with estrogens and gestagens in peri- and post-menopause].
abstract: Hormone therapy with estrogens (combined with progestin for women who have not been hysterectomized) is the most efficacious treatment for climacteric symptoms. A few years ago hormone therapy was considered to be an ideal prevention for cardio-vascular disease, osteoporosis, dementia and other diseases. Large prospective randomized trials have changed this paradigm. Hormone therapy should only be used with a clear indication (moderate to severe climacteric symptoms and - with limitations - prevention of osteoporosis). The lowest effective dose should be used for the shortest possible time.
authors.affiliation: Universitäts-Frauenklinik, Robert-Koch-Strasse 40, 37075, Göttingen, Deutschland. emons@med.uni-goettingen.de
authors.forename: G
authors.initials: G
authors.lastname: Emons
mesh_terms: D015914:Estrogen Replacement Therapy / Q000379:methods* / Q000639:trends*; D004967:Estrogens / Q000008:administration & dosage*; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000517:prevention & control*; D011372:Progestins / Q000008:administration & dosage*
chemical_list: D004967:Estrogens; D011372:Progestins