title: Determination methods for biologically active compounds by ultra-performance liquid chromatography coupled with mass spectrometry: application to the analyses of pharmaceuticals, foods, plants, environments, metabonomics, and metabolomics.
abstract: This review summarizes the determination methods for biologically active compounds, such as pharmaceuticals, agrochemicals, and biogenic amines, by ultra-performance liquid chromatography coupled with mass spectrometry. The typical applications using the method are also described in this study, together with the characteristics of the methods.
authors.affiliation: Division of Bio-Analytical Chemistry, School of Pharmaceutical Sciences, and Global COE Program, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. toyooka@u-shizuoka-ken.ac.jp
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Toyo'oka
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D005504:Food Analysis / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000378:metabolism; D028321:Plant Preparations / Q000032:analysis; D010944:Plants / Q000737:chemistry* / Q000378:metabolism
chemical_list: D004364:Pharmaceutical Preparations; D028321:Plant Preparations