title: [Study on preparation of phenols gastric floating tablet].
abstract: OBJECTIVE
  To study the preparation of phenols gastric floating tablet.
  
  
  METHODS
  The tablets which were prepared using Eudragit IV, HPMC(K4M), MCC101 and Octadecanol as excipients were evaluated by vitro floatation and releasing performance. The pressure of preparationg was also study to select the optimal preparation.
  
  
  RESULTS
  The tablets were successfully prepared in which the drug, Eudragit IV, Octadecanol were 31% respectively,and MCC101 was 7%. And 3-4 kg was found to be the eligible pressure.
  
  
  CONCLUSIONS
  The study was found to be effective in the process of phenols gastric floating tablet.
authors.affiliation: Beijing University of Traditional Chinese Medicine, Beijing 100102, China.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Zhai
authors.forename: Jian
authors.initials: J
authors.lastname: Ni
authors.forename: Yu-Long
authors.initials: YL
authors.lastname: Gu
mesh_terms: D004337:Drug Carriers; D005079:Excipients / Q000737:chemistry; D005765:Gastrointestinal Agents / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D011109:Polymethacrylic Acids / Q000737:chemistry; D013607:Tablets; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004337:Drug Carriers; D005079:Excipients; D005765:Gastrointestinal Agents; D010636:Phenols; D011109:Polymethacrylic Acids; D013607:Tablets; C038300:methylmethacrylate-methacrylic acid copolymer