title: [Clinical significance of rapid increase of heart rate at onset of treadmill exercise test].
abstract: OBJECTIVE
  To analyze the correlation between rapid increase of heart rate at onset of electrocardiogram treadmill exercise test and coronary artery lesion.
  
  
  METHODS
  We selected 245 patients who underwent electrocardiogram treadmill exercise and coronary angiography. The patients were divided into a coronary heart disease (CHD) group and a non-CHD group according to the Results of coronary angiography. The patients of the CHD group were divided into a single-vessel disease group, a double-vessel disease group, and a triplet-vessel disease group. The increased heart rate during the first minute (DeltaHR 1minute) of treadmill exercise test and the extent of coronary artery lesion were analyzed.
  
  
  RESULTS
  DeltaHR 1minute in the CHD group was significantly higher than that in the non-CHD group(P<0.01). DeltaHR 1minute had an increasing trend with the severity of coronary artery lesion. DeltaHR 1minute was positively correlated to the depression of ST segment and the severity of coronary artery lesion(r=0.252,0.470, P<0.01).
  
  
  CONCLUSIONS
  Patients with CHD have an increased DeltaHR 1minute. DeltaHR 1minute can be one of the indexes to estimate the extent of myocardial ischemia and coronary artery lesion.
authors.affiliation: Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha, China. luolin5168@yahoo.com.cn
authors.forename: Lin
authors.initials: L
authors.lastname: Luo
authors.forename: Shui-ping
authors.initials: SP
authors.lastname: Zhao
authors.forename: Yang
authors.initials: Y
authors.lastname: Cao
authors.forename: Hui-jun
authors.initials: HJ
authors.lastname: Ye
mesh_terms: D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000175:diagnosis* / Q000503:physiopathology; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged