Transient encephalopathy with reversible white matter lesions: a case report.
We report on a boy with bilateral optic nerve hypoplasia and mild psychomotor retardation. At 1 year and 9 months of age, he was admitted to hospital with a cluster of febrile convulsions and unconsciousness. Magnetic resonance imaging (MRI) revealed widespread areas of high signal intensity on diffusion-weighted imaging of the deep cerebral white matter and corpus callosum. This imaging disappeared at five days of illness. No atrophy or abnormalities were noted on the 6-month follow-up MRI. Despite full recovery after the acute episode, the patient showed retarded developmental progress. We discuss the differential diagnosis for this case.
Yokoyama
Atsushi
A
Department of Pediatrics, Shimane Prefectural Central Hospital, Himehara 4-1-1, Izumo, Shimane 693-8555, Japan. atsushiy@grape.med.tottori-u.ac.jp
Saito
Yoshiaki
Y
Kato
Fumihide
F
Asai
Koichi
K
Maegaki
Yoshihiro
Y
Ohno
Kousaku
K
D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D007223:Infant; D008297:Male; D019957:Motor Skills Disorders / Q000150:complications / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000150:complications / Q000473:pathology*