[Drug treatment of hypertension in hemodialysed patients].
A fraction of the dialyzed patients remains hypertensive despite achievement of the "dry weight" and will eventually require a pharmacological antihypertensive treatment. There is only scarce randomized intervention trials available in those patients so it is difficult to estimate whether the cardiovascular benefit of the treatment is related to blood pressure lowering per se or to class or drug specific properties. This paper reviews the different class of antihypertensive drugs focusing on their advantages and disadvantages in dialysis patients. On a practical ground, prescription will be driven by pharmacokinetics considerations and mostly according to specific indications pertinent to cardiovascular complications associated with hypertension.
Hannedouche
T
T
Service de Néphrologie, Hôpitaux Universitaires de Strasbourg, 67091 Strasbourg cedex, France.
Krumme
T
T
Benaicha
A
A
Bazin
D
D
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic; D006435:Renal Dialysis; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics