title: Ictal/interictal EEG patterns and functional neuroimaging findings in subcortical band heterotopia: report of three cases and review of the literature.
abstract: Subcortical band heterotopia (SBH) is a rare, genetic disorder of neuronal migration, which is seen almost exclusively in females. Little is known about the functionality of the band heterotopia, in terms of both physiology and pathology, in this malformation. Patients are reported to have several different types of seizures, which are usually drug resistant. Interictal EEG findings are known to correlate with the type of seizures, however less is known about the ictal EEG patterns. We present 3 female patients who were investigated at our center with video-scalp EEG monitoring, interictal single photon emission computed tomography (SPECT), functional magnetic resonance (MR) imaging (fMRI) and MR spectroscopy (MRS) besides routine MR imaging. They had several different types of seizures, and one of them reported also having circling seizures that have not been reported previously in patients with SBH. Ictal EEG recordings were remarkable for their unusual patterns of propagation. The findings in structural and functional neuroradiological investigations are discussed in light of the literature.
authors.affiliation: Hacettepe University School of Medicine, Department of Neurology, Ankara, Turkey. nesedericioglu@yahoo.com
authors.forename: Nese
authors.initials: N
authors.lastname: Dericioglu
authors.forename: Kader Karli
authors.initials: KK
authors.lastname: Oguz
authors.forename: Eser Lay
authors.initials: EL
authors.lastname: Ergun
authors.forename: Fadime Irsel
authors.initials: FI
authors.lastname: Tezer
authors.forename: Serap
authors.initials: S
authors.lastname: Saygi
mesh_terms: D000328:Adult; D054221:Classical Lissencephalies and Subcortical Band Heterotopias / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D015899:Tomography, Emission-Computed, Single-Photon