title: [Radical resection of a hilar cholangiocarcinoma. Indications and results].
abstract: OBJECTIVE
  The objective of the study is to review our experience in the surgical treatment of Klatskin tumours, after the systematic application of the current concepts of radicalism. Sixty-one patients resected using these criteria are presented.
  
  
  METHODS
  We have studied 154 patients. Surgery was ruled out in 59 (41%) of them, and a liver transplant was performed on 9; of the 86 patients operated on, 25 were resectable. Resectability was 71% (of the 86 patients operated on) and was 39% of the total patients. The results during two periods are compared, 1989-1998 (pre-99) and 1999-2007 (post-99).
  
  
  RESULTS
  On comparing the two periods, resectability increased from 26% to 53% (p = 0.01), the percentage of exploratory laparotomies decreasing (pre: 45% vs post: 22%; p = 0.04). Hepatectomy was performed in 53 cases (87%), being most frequent post-99 (pre: 66% vs post: 91%; p = 0.02). Resection of the caudate was performed in 48 cases (90%), being most frequent in the post-99 period (pre: 40% vs pos: 89%; p = 0.005). Post-operative morbidity was 77%, with 28% the patients being re-operated on, and the post-operative mortality was 16.4%, with no significant differences between the periods. Actuarial survival at 5 years increases in the post-99 period (pre: 26% vs post: 51%; p = 0.06).
  
  
  CONCLUSIONS
  Adequate staging, associated with an aggressive surgical strategy can achieve a greater than 50% resectability rate. The post-operative morbidity and mortality of this strategy is high, but the survival that it achieves justifies this.
authors.affiliation: Servicio de Cirugía, Hospital Universitario de Bellvitge, Universidad de Barcelona, L'Hospitalet de Llobregat, Barcelona, España. 31513llg@comb.es.
authors.forename: Laura
authors.initials: L
authors.lastname: Lladó
authors.forename: Emilio
authors.initials: E
authors.lastname: Ramos
authors.forename: Jaume
authors.initials: J
authors.lastname: Torras
authors.forename: Joan
authors.initials: J
authors.lastname: Fabregat
authors.forename: Rosa
authors.initials: R
authors.lastname: Jorba
authors.forename: Carles
authors.initials: C
authors.lastname: Valls
authors.forename: David
authors.initials: D
authors.lastname: Julià
authors.forename: Teresa
authors.initials: T
authors.lastname: Serrano
authors.forename: Joan
authors.initials: J
authors.lastname: Figueras
authors.forename: Antoni
authors.initials: A
authors.lastname: Rafecas
mesh_terms: D001650:Bile Duct Neoplasms / Q000601:surgery*; D018281:Cholangiocarcinoma / Q000601:surgery*; D005260:Female; D006500:Hepatic Duct, Common; D006801:Humans; D018285:Klatskin Tumor / Q000601:surgery*; D008297:Male; D008875:Middle Aged