Vanadium uptake by biomass of Coprinus comatus and their effect on hyperglycemic mice.
The Vanadium uptake by Coprinus comatus and their co-effect on hyperglycemic mice were studied. By fermentation and AAS analysis, the optimal concentration of vanadium in medium was 0.4%, and the content of vanadium accumulated in the mycelia was 3,528.0 microg/g. At the concentration of 0.4%, the vanadium-associated toxicity was reduced, and its anti-diabetic effects were maintained.
Han
Chunchao
C
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, People's Republic of China. sdscipaper@126.com
Cui
Bo
B
Wang
Yingzi
Y
D000818:Animals; D018533:Biomass; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000187:drug effects; D003302:Coprinus / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D005285:Fermentation; D051379:Mice; D008820:Mice, Obese; D014639:Vanadium / Q000378:metabolism* / Q000494:pharmacology* / Q000633:toxicity
D001786:Blood Glucose; D014639:Vanadium