title: Evaluation the Clinitek status automated dipstick analysis device for semiquantitative testing of canine urine.
abstract: The aim of this prospective study was to evaluate the Clinitek status analyser using Multistix10SG/Microalbustix dipsticks (all: Siemens Dx) for canine urine (n=101) compared to reference methods: visual reading (Combur9 dipstick, Roche), refractometry, microscopy, and quantitative protein/creatinine analysis (Pentra400, AxonLab). The automated analyses were done twice and visual tests were performed by two examiners. An excellent to good concordance was demonstrated between the first/second analysis with the Multistix10SG and the Combur9 dipstick, respectively with Cohen's kappa-values ranging from 0.776 to 1.000. Agreement between both dipsticks was good for glucose (kappa=0.753), blood (kappa=0.793), protein (kappa=0.788), and moderate for bilirubin (kappa=0.431) and ketones (kappa=0.540). In 6/101 specimens, false positive ketone reactions were obtained with the Multistix10SG. Multistix10SG could not be used for determination of pyuria or specific gravity. Semiquantitative/quantitative protein results correlated well (rho=0.90) and creatinine measurements moderately (rho=0.76). Due to automated data transmission to the laboratory information system, the Clinitek status is of advantage in veterinary laboratories/clinics.
authors.affiliation: Department of Veterinary Clinical Sciences, Justus-Liebig University Giessen, Frankfurterstrasse 129, 35392 Giessen, Germany. Natalie.Bauer@vetmed.uni-giessen.de
authors.forename: N
authors.initials: N
authors.lastname: Bauer
authors.forename: S
authors.initials: S
authors.lastname: Rettig
authors.forename: A
authors.initials: A
authors.lastname: Moritz
mesh_terms: D000818:Animals; D001331:Automation; D004283:Dog Diseases / Q000175:diagnosis / Q000652:urine; D004285:Dogs / Q000652:urine*; D006029:Glycosuria / Q000175:diagnosis / Q000662:veterinary; D006417:Hematuria / Q000175:diagnosis / Q000662:veterinary; D011934:Reagent Strips; D012680:Sensitivity and Specificity; D016482:Urinalysis / Q000295:instrumentation / Q000379:methods / Q000662:veterinary*
chemical_list: D011934:Reagent Strips