title: Meningitis caused by Alcaligenes xylosoxidans in a patient with HIV/AIDS.
abstract: The purpose of the present work was to inform about the first case of meningitis associated to the bacteria Alcaligenes xylosoxidans in a patient with HIV/AIDS. The patient was a 46-year-old male, with the antecedent of have been diagnosed for HIV/ AIDS, who attended in the Hospital Universitario de Colima, Mexico, with fever, shock and meningismus. The study of the cerebrospinal fluid showed pleocytosis, elevated protein levels and hypoglycorrhachia. The culture yielded the presence of Alcaligenes xylosoxidans with sensitivity to ciprofloxacin. After 14 days of treatment with this antibiotic, the patient showed neurologic improvement and was able to continue with his outpatient antiretroviral treatment. The present case shows the importance of the inclusion of this bacterium in the differential diagnosis of the neurological infections in HIV/AIDS patients and emphasizes the importance of considering the bacterial meningitis in this population.
authors.affiliation: Hospital Regional Universitario, Secretaría de Salud y Bienestar Social del Estado de Colima, Colima, Mexico. fespin@cgic.ucol.mx
authors.forename: F
authors.initials: F
authors.lastname: Espinoza-Gómez
authors.forename: O A
authors.initials: OA
authors.lastname: Newton-Sánchez
authors.forename: V
authors.initials: V
authors.lastname: Melnikov
authors.forename: O
authors.initials: O
authors.lastname: Virgen-González
authors.forename: J
authors.initials: J
authors.lastname: Unrau
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000421:Alcaligenes / Q000302:isolation & purification*; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin