title: [Effects of immunotherapy with infantile recurrent respiratory tract infection by Chinese materia medica].
abstract: OBJECTIVE
  To explore the effect of Chinese materia medica on immune intervention of infantile recurrent respiratory tract infection.
  
  
  METHODS
  Thirty-one children of recurrent respiratory tract infection were randomly divided into two groups: therapy group was treated with oral Chinese materia medica (b. i. d), control group was only treated with oral carboxymethyl liquor (< 4 years, 3 mL; 4-7 years, 5 mL; > 7 years, 7 mL, t. i. d). The change of IL-12,TNF-alpha, IL-6, IL-13, IL-6 and IL-4 in different time were observed and analyzes.
  
  
  RESULTS
  Compared with the control group, the level of IL-12 and IL-2 was significantly increased after treatment of oral Chinese materia medica (P < 0.01), however, the level of TNF-alpha, IL-13, IL-4, and IL-6 was decreased after treatment (P < 0.01). During one years follow-up study, the frequency of respiratory infection every year of therapy group was significantly decreased than that of control group.
  
  
  CONCLUSIONS
  Chinese materia medica could prevent infantile recurrent respiratory tract infection effectively, increase humoral immunity function and ensure normal growth in children.
authors.affiliation: Medical College of Jinhua College of Profession & Technology College, Jinhua 321000, China. ghh53021@163.com
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Hu
authors.forename: Jing-He
authors.initials: JH
authors.lastname: Wang
authors.forename: Jing-Chan
authors.initials: JC
authors.lastname: Yao
authors.forename: Xun-Tong
authors.initials: XT
authors.lastname: Shi
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008419:Materia Medica / Q000627:therapeutic use*; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000628:therapy*
chemical_list: D008419:Materia Medica