[Studies on chemical constituents from roots of Mirabilis jalapa].
OBJECTIVE
To investigate the anti-HIV constituents from the root of Mirabilis jalapa.


METHODS
The compounds were isolated by column chromatography on silica gel, Sephadex LH - 20, MCI-gel CHP-20P and RP-18. The structure were identified by means of NMR and MS analyses (1H-NMR, 13C-NMR, MS).


RESULTS
Eleven compounds were isolated and identified as astragaloside II (1), astragaloside II (2), astragaloside IV (3), astragaloside VI (4), flazin (5), 4'-hydroxy-2, 3-dihydroflavone 7-beta-D-glucopyranoside (6), gingerglycolipid A (7), 3, 4-dihydroxybenzaldehyd (8), p-hydroxybenzaldehyde (9), beta-sitosterol (10) and daucosterol (11).


CONCLUSIONS
Compounds 1-9 were obtained from this genus for the first time.
Lai
Guo-Fang
GF
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
Luo
Shi-De
SD
Cao
Jian-Xin
JX
Wang
Yi-Fen
YF
D001547:Benzaldehydes / Q000032:analysis / Q000737:chemistry; D002243:Carbolines / Q000032:analysis / Q000737:chemistry; D002850:Chromatography, Gel; D005663:Furans / Q000032:analysis / Q000737:chemistry; D038983:Galactolipids / Q000032:analysis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D039282:Mirabilis / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D012855:Sitosterols / Q000032:analysis / Q000737:chemistry
D001547:Benzaldehydes; D002243:Carbolines; D005663:Furans; D038983:Galactolipids; D012855:Sitosterols; C055780:flazin; C089057:gingerglycolipid A; C025473:gamma-sitosterol; C011483:4-hydroxybenzaldehyde; C011015:lyoniside