title: Characterization of nanogap chemical reactivity using peptide-capped gold nanoparticles and electrical detection.
abstract: Nanogaps are usually combined with synthetic or biological molecules to produce nanodevices having novel properties. This combination is better realized by controlling the chemical properties of the nanogap. We show here that the presence of a specific chemical group inside nanogaps (30-90 nm) can be probed electrically using 10 nm gold nanoparticles derivatized by complementary functional groups. 100-10(4)-fold current increases were observed following the site-specific insertion of gold nanoparticles into the nanogap.
authors.affiliation: Institut d'Electronique de Microélectronique et de Nanotechnologie, UMR CNRS 8520, Dpt ISEN, 41 Bd Vauban, 59046 Lille Cedex, France.
authors.forename: Lionel
authors.initials: L
authors.lastname: Marcon
authors.forename: Didier
authors.initials: D
authors.lastname: Stiévenard
authors.forename: Oleg
authors.initials: O
authors.lastname: Melnyk
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D004563:Electrochemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D000447:Aldehydes; D010455:Peptides; D006046:Gold