title: [Multifactor stress-echocardiography in the diagnostics of coronary artery disease at the pre-hospital stage].
abstract: The aim of the study was to assess tolerance to and the appropriateness of multi-factor stress-echoCG for the diagnostics of initial stages of coronary artery disease (CAD) in out-patient practice. The subjects of the study were 25 men aged 32 to 51 (mean age 43.2 +/- 4.9 years). Of these patients, 10 men with heartache were suspected to have CAD, and 15 suffered from stage II essential hypertension (EH). In five patients (including four with stage II EH) chest pain which was untypical for stenocardia, was observed, and in five other patients rare attacks of class lexertional stenocardia took place. All the patients underwent stress-echoCG with a combination of two stress agents: transesophageal left ventricular cardiostimulation (TEES) and dipiridamol test (DP). Stress echoCG was positive in eight (32%) of the patients including seven subjects with stenoses of less than 50% of anterior interventricular artery (AIVA) diameter and one patient with stenoses of 50 to 70% of AIVA diameter. Of these patients, 20% (n = 5) had stage II EH. There were no complications or undesirable reactions. The method of multifactor stress-echoCG allowed for the early diagnosis of CAD in 32% of patients, in whom conventional functional diagnostic techniques were of little informative value, including the 20% of patients with stage II EH. Thus, multifactor stress-echoCG (DP+ TEES) is an approachable, informative, and safe method of early CAD diagnostics, which may be recommended for wide application in outpatient departments for a rational selection of patients for further CG and planning therapeutic tactics in CAD patients.
authors.forename: G F
authors.initials: GF
authors.lastname: Tursunova
authors.forename: V I
authors.initials: VI
authors.lastname: Baksheev
authors.forename: N M
authors.initials: NM
authors.lastname: Kolomoets
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003937:Diagnosis, Differential; D025401:Echocardiography, Stress / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D015203:Reproducibility of Results; D013997:Time Factors