title: Effects of cardiac rehabilitation program on exercise capacity and chronotropic variables in patients with orthotopic heart transplant.
abstract: OBJECTIVE
  To evaluate the effects of home- and hospital-exercise programs on exercise capacity and chronotropic variables in patients with heart transplantation.
  
  
  METHODS
  Forty patients were randomized into two groups either hospital- or home-based exercise program. The patients were compared, before and after the rehabilitation program, with respect to maximal oxygen uptake (pVO(2)), chronotropic variables [heart rate reserve (HRR(e)), heart rate recovery (HRR(1)), and chronotropic response index (CRI)] and Duke Treadmill Score (DTS).
  
  
  RESULTS
  Hospital-based exercise group has shown a significant recovery in post-exercise pVO(2) (pre-exercise 16.73 +/- 3.9 ml/kg/min, post-exercise 19.53 +/- 3.89 ml/kg/min, P = 0.002) and DTS (pre-exercise 4.74 +/- 1.17, post-exercise 5.61 +/- 1.11, P = 0.002). A significant recovery in favor of the hospital-based exercise group was found in HRR(e) (pre-exercise 26.9 +/- 14.6, post-exercise 34.6 +/- 14.6, P = 0.01). No significant change was observed in HRR(1) (pre-exercise -1.38 +/- 1.04, post-exercise -1.21 +/- 1.89, P = 0.49) and CRI (pre-exercise 0.44 +/- 0.23, post-exercise 0.48 +/- 0.20, P = 0.15) in hospital-based exercise group. No significant change was observed in any parameters of home-based group (P > 0.05).
  
  
  CONCLUSIONS
  A significant recovery was observed both in the functional capacity and the chronotropic response in hospital-based exercise program. Exercise programs that are planned to be performed under supervision in rehabilitation units are useful for the patients with heart transplant in terms of the exercise capacity and chronotropic variables.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Ege University, 35100 Bornova, Izmir, Turkey. haleuzum76@hotmail.com
authors.forename: Hale
authors.initials: H
authors.lastname: Karapolat
authors.forename: Sibel
authors.initials: S
authors.lastname: Eyigor
authors.forename: Mehdi
authors.initials: M
authors.lastname: Zoghi
authors.forename: Tahir
authors.initials: T
authors.lastname: Yagdi
authors.forename: Sanem
authors.initials: S
authors.lastname: Nalbantgil
authors.forename: Berrin
authors.initials: B
authors.lastname: Durmaz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ozbaran
mesh_terms: D000328:Adult; D005080:Exercise Test / Q000379:methods; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D016027:Heart Transplantation / Q000502:physiology / Q000534:rehabilitation*; D018575:Home Care Services, Hospital-Based; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D016896:Treatment Outcome