title: Olefin cross-metathesis reactions at room temperature using the nonionic amphiphile "PTS": just add water.
abstract: The first examples of unsymmetrical olefin cross-metathesis reactions in water, involving water-insoluble substrates, at room temperature and using commercially available catalysts are reported. The key to success is to include small percentages of the nonionic, vitamin E-based amphiphile "PTS". The nanometer micelles formed accommodate water-insoluble substrates, along with a readily available Ru-based metathesis catalyst. Reactions proceed at ambient temperatures with high efficiency and very high E-selectivity, and products are easily isolated.
authors.affiliation: Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106, USA. lipshutz@chem.ucsb.edu
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
authors.forename: Grant T
authors.initials: GT
authors.lastname: Aguinaldo
authors.forename: Subir
authors.initials: S
authors.lastname: Ghorai
authors.forename: Karl
authors.initials: K
authors.lastname: Voigtritter