title: Mutations in influenza A virus (H5N1) and possible limited spread, Turkey, 2006.
abstract: We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died.
authors.affiliation: Acibadem Genetic Diagnosis Center, Istanbul, Turkey. ealtiok@asg.com.tr
authors.forename: Ender
authors.initials: E
authors.lastname: Altiok
authors.forename: Fulya
authors.initials: F
authors.lastname: Taylan
authors.forename: Osman S
authors.initials: OS
authors.lastname: Yenen
authors.forename: Gülşah
authors.initials: G
authors.lastname: Demirkeser
authors.forename: Mürvet
authors.initials: M
authors.lastname: Bozaci
authors.forename: Derya
authors.initials: D
authors.lastname: Onel
authors.forename: Birsen
authors.initials: B
authors.lastname: Akcadag
authors.forename: A Selma
authors.initials: AS
authors.lastname: Iyisan
authors.forename: Meral
authors.initials: M
authors.lastname: Ciblak
authors.forename: Emel
authors.initials: E
authors.lastname: Bozkaya
authors.forename: Sirin
authors.initials: S
authors.lastname: Yuksel
authors.forename: Selim
authors.initials: S
authors.lastname: Badur
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002645:Chickens / Q000821:virology*; D004196:Disease Outbreaks; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D007251:Influenza, Human / Q000453:epidemiology / Q000821:virology*; D009154:Mutation; D014421:Turkey / Q000453:epidemiology