title: Spathoside, a cerebroside and other antibacterial constituents of the stem bark of Spathodea campanulata.
abstract: Spathoside, a new cerebroside was isolated from the stem bark of Spathodea campanulata, besides known compounds (n-alkanes, linear aliphatic alcohols, sitosterol and their esters, beta-sitosterol-3-O-beta-D-glucopyranoside, oleanolic acid, pomolic acid, p-hydroxybenzoic acid and phenylethanol esters). The structures of the isolated compounds were established by spectroscopic studies. The antibacterial activity of the isolated compounds against a wide range of microorganisms was examined. They inhibited significantly the growth of some gram-positive and -negative bacteria.
authors.affiliation: Faculté des Sciences, Laboratoire de Substances Naturelles et Synthèse Organique, Département de Chimie Organique, Université de Yaoundé I, BP 812 Yaoundé, Cameroun.
authors.forename: Emmanuel Jean Teinkela
authors.initials: EJ
authors.lastname: Mbosso
authors.forename: Silvère
authors.initials: S
authors.lastname: Ngouela
authors.forename: Jules Clément Assob
authors.initials: JC
authors.lastname: Nguedia
authors.forename: Véronique
authors.initials: V
authors.lastname: Penlap
authors.forename: Michel
authors.initials: M
authors.lastname: Rohmer
authors.forename: Etienne
authors.initials: E
authors.lastname: Tsamo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D029402:Bignoniaceae / Q000737:chemistry*; D002554:Cerebrosides / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D002554:Cerebrosides; C532686:spathoside