title: Sclerodermiform linear lupus erythematosus: A distinct entity or coexistence of two autoimmune diseases?
abstract: The coexistence of features of chronic cutaneous lupus erythematosus and scleroderma in the same skin lesions is very infrequent and has only been reported in 3 patients. This exceedingly rare condition has been named "sclerodermiform linear lupus erythematosus." We describe a new case of this dermatosis. Although the cause remains obscure, possible explanations include mosaicism following Blaschko's lines or the transfer of microchimerisms that mount a chronic graft-versus-host-like reaction. We suggest that these features may be a distinct clinicopathologic disorder characterized by an initial lichenoid reaction followed by the production of excessive, abnormal connective tissue.
authors.affiliation: Department of Dermatology, Hospital Clínic, University of Barcelona, Barcelona, Spain.
authors.forename: Marc
authors.initials: M
authors.lastname: Julià
authors.forename: Jose M
authors.initials: JM
authors.lastname: Mascaró
authors.forename: Antonio
authors.initials: A
authors.lastname: Guilabert
authors.forename: Esperanza
authors.initials: E
authors.lastname: Navarra
authors.forename: Juan
authors.initials: J
authors.lastname: Ferrando
authors.forename: Carmen
authors.initials: C
authors.lastname: Herrero
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000473:pathology; D012594:Scleroderma, Localized / Q000150:complications* / Q000473:pathology