Spathoside, a cerebroside and other antibacterial constituents of the stem bark of Spathodea campanulata.
Spathoside, a new cerebroside was isolated from the stem bark of Spathodea campanulata, besides known compounds (n-alkanes, linear aliphatic alcohols, sitosterol and their esters, beta-sitosterol-3-O-beta-D-glucopyranoside, oleanolic acid, pomolic acid, p-hydroxybenzoic acid and phenylethanol esters). The structures of the isolated compounds were established by spectroscopic studies. The antibacterial activity of the isolated compounds against a wide range of microorganisms was examined. They inhibited significantly the growth of some gram-positive and -negative bacteria.
Mbosso
Emmanuel Jean Teinkela
EJ
Faculté des Sciences, Laboratoire de Substances Naturelles et Synthèse Organique, Département de Chimie Organique, Université de Yaoundé I, BP 812 Yaoundé, Cameroun.
Ngouela
Silvère
S
Nguedia
Jules Clément Assob
JC
Penlap
Véronique
V
Rohmer
Michel
M
Tsamo
Etienne
E
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D029402:Bignoniaceae / Q000737:chemistry*; D002554:Cerebrosides / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry
D000900:Anti-Bacterial Agents; D002554:Cerebrosides; C532686:spathoside