title: Pattern of hepatitis C virus genotypes in HIV infected patients in RIMS, Hospital, Imphal, Manipur.
abstract: The present study was carried out to find the pattern of genotype distribution of Hepatitis C virus. Twenty-three Hepatitis C virus positive serum samples in various age-groups of both sexes attending, Microbiology Department, RIMS during the period from September 2002 to December 2004 were studied for Hepatitis C genotype. These HCV positive serum samples were sent to National Institute of Cholera and Enteric Diseases, Kolkata. The serum samples were tested for HCV-RNA by qualitative RT-PCR test and then genotyped by type specific RT-PCR. Out of 23 serum samples, 22 were males. All the 23 HCV positive serum samples were also tested positive for HCV-RNA by qualitative RT-PCR. Majority of the cases belonged to the age group of 31-40 years. Higher percentage of Hepatitis C cases were Injecting Drug Users and next to it were patients with multiple sexual contacts. Among the IDUs, Hepatitis C virus 3a type was the commonest genotype (61.1%) followed by 1b (22.2%) and 3b (16.7%) respectively. Hepatitis C genotype 3a was predominant (52.2%) followed by 1b (26%) and 3b (21.8%). HCV genotype 3a occurred most commonly in the age group of 21-40 years.
authors.affiliation: Department of Microbiology, Regional Institute of Medical Sciences, Imphal Manipur.
authors.forename: Pratita Devi
authors.initials: PD
authors.lastname: Pukhrambam
authors.forename: Ng Brajachand
authors.initials: NB
authors.lastname: Singh
authors.forename: Lokhendro H
authors.initials: LH
authors.lastname: Singh
authors.forename: Kh Sulochana
authors.initials: KhS
authors.lastname: Devi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood / Q000235:genetics; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000821:virology
chemical_list: D012367:RNA, Viral