title: Attitude to nephrolithiasis in the potential living kidney donor: a survey of the German kidney transplant centers and review of the literature.
abstract: Living donor kidney transplantation (LD-KTX) is increasing worldwide. With the prevalence of urolithiasis ranging between 4% and 15%, the number of donors with current nephrolithiasis or a history of the disease will increase as well. A questionnaire was sent to all German centers with LD-KTX programs (urologists and general surgeons). Answers were compared for differences between urological and surgical kidney transplant centers. Response rate was 74%. Nephrolithiasis at the time of KTX is an exclusion criterion at 36% of the German centers (58% urological/19% surgical, chi(2) = 4.65, p = 0.03, Fishers exact p = 0.05), 96% of the centers accept kidney donors with a history of nephrolithiasis. The length of the stone-free episode is regarded as relevant by 42% of all centers (58% urological vs. 32% surgical centers, p = ns). Stone composition is a criterion for 54% of centers (66% vs. 44%, p = ns). More than half of the centers accept a history of cystine stones, almost all centers of struvite and urate stones. Donors with current nephrolithiasis were less commonly accepted by urologists than by general surgeons. For almost all centers history of nephrolithiasis does not preclude living kidney donation. Stone composition proved to be of little relevance for decision making.
authors.affiliation: Department of Urology, Charité-Universitätsmedizin Berlin, Germany. markus.giessing@charite.de
authors.forename: Markus
authors.initials: M
authors.lastname: Giessing
authors.forename: Florian
authors.initials: F
authors.lastname: Fuller
authors.forename: Max
authors.initials: M
authors.lastname: Tuellmann
authors.forename: Lutz
authors.initials: L
authors.lastname: Liefeld
authors.forename: Torsten
authors.initials: T
authors.lastname: Slowinski
authors.forename: Klemens
authors.initials: K
authors.lastname: Budde
authors.forename: Stefan A
authors.initials: SA
authors.lastname: Loening
mesh_terms: D001291:Attitude of Health Personnel; D046148:Donor Selection; D006306:Health Surveys; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D053040:Nephrolithiasis / Q000175:diagnosis*; D017410:Practice Guidelines as Topic; D011795:Surveys and Questionnaires; D009927:Tissue and Organ Procurement