A coumarin-derived fluorescence probe selective for magnesium.
Two different coumarin derivatives have been connected via an imine linkage to obtain a new fluorescence signaling system. This compound itself does not show any emission due to rapid isomerization around the C[double bond]N bond. However, in the presence of a Mg(II) ion, this isomerization is stopped because of bonding to the metal ion resulting in high-intensity (approximately 550-fold) emission. Other metal ions like Li(I), Ca(II), and Zn(II) show very little emission, while biologically relevant transition-metal ions do not show any emission. In this way, the Mg(II) ion can be detected in the presence of these ions.
Ray
Debdas
D
Department of Chemistry, Indian Institute of Technology, Kanpur 208016, India.
Bharadwaj
P K
PK
D003374:Coumarins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
D003374:Coumarins; D005456:Fluorescent Dyes; C030123:coumarin; D008274:Magnesium