title: Bilateral posterior ischemic optic neuropathy associated with use of sildenafil.
authors.forename: Daniel Hsien-Wen
authors.initials: DH
authors.lastname: Su
authors.forename: Pei-San
authors.initials: PS
authors.lastname: Ang
authors.forename: Sharon Lee-Choon
authors.initials: SL
authors.lastname: Tow
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000368:Aged; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects; D001262:Atenolol / Q000008:administration & dosage; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004110:Diltiazem / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions / Q000502:physiology; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000737:chemistry; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology; D007022:Hypotension / Q000139:chemically induced / Q000503:physiopathology; D008297:Male; D009900:Optic Nerve / Q000098:blood supply / Q000187:drug effects* / Q000503:physiopathology; D018917:Optic Neuropathy, Ischemic / Q000139:chemically induced* / Q000503:physiopathology; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects / Q000032:analysis; D010879:Piperazines / Q000009:adverse effects* / Q000032:analysis; D011687:Purines / Q000009:adverse effects / Q000032:analysis; D012161:Retinal Artery / Q000187:drug effects* / Q000503:physiopathology; D012307:Risk Factors; D000068677:Sildenafil Citrate; D019821:Simvastatin / Q000008:administration & dosage; D013450:Sulfones / Q000009:adverse effects* / Q000032:analysis; D015354:Vision, Low / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D065607:Cytochrome P-450 Enzyme Inhibitors; D004365:Drugs, Chinese Herbal; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D001262:Atenolol; D003577:Cytochrome P-450 Enzyme System; D019821:Simvastatin; D000068677:Sildenafil Citrate; D004110:Diltiazem