title: New fluorogenic dansyl-containing calix[4]arene in the partial cone conformation for highly sensitive and selective recognition of lead(II).
abstract: A new efficient and highly selective fluorescent chemosensor for determination of Pb (2+) has been obtained by covalent attachment of two pendent proton-ionizable dansylcarboxamide groups to the calix[4]arene preorganized in the partial cone conformation. This geometry of the calixarene moiety was chosen on the basis of the prior (1)H NMR study of conformations adopted by the flexible dansyl-containing prototype upon complexation with lead ion. In acidic MeCN-H2O (1:1 v/v) solutions, the partial cone fluoroionophore allowed for detection of Pb (2+) at the levels as low as 2.5 ppb, which is totally compatible with the regulations of the U.S. Environmental Protection Agency and the World Health Organization on the limiting content of this hazardous pollutant in drinking water.
authors.affiliation: Department of Chemistry, Howard University, 525 College Street NW, Washington, D.C. 20059, USA.
authors.forename: Nicole M
authors.initials: NM
authors.lastname: Buie
authors.forename: Vladimir S
authors.initials: VS
authors.lastname: Talanov
authors.forename: Raymond J
authors.initials: RJ
authors.lastname: Butcher
authors.forename: Galina G
authors.initials: GG
authors.lastname: Talanova
mesh_terms: D047250:Calixarenes / Q000737:chemistry*; D002413:Cations, Divalent / Q000737:chemistry; D018360:Crystallography, X-Ray; D003619:Dansyl Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007854:Lead / Q000032:analysis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010636:Phenols / Q000737:chemistry*
chemical_list: D002413:Cations, Divalent; D003619:Dansyl Compounds; D005456:Fluorescent Dyes; D010636:Phenols; C121325:calix(4)arene; D047250:Calixarenes; D007854:Lead