[Study on changes of CT performance and pulmonary function in renal transplant recipients with pneumocystis pneumonia].
OBJECTIVE
To investigate dynamic changes of CT performance and pulmonary function in renal transplant recipients with pneumocystis pneumonia.


METHODS
A retrospective analysis was made upon the clinic data of chest CT, arterial blood gas and pulmonary function in renal transplant recipients with pneumocystis pneumonia from 2002 to 2006 in the first affiliated hospital of Wenzhou Medical College.


RESULTS
16 cases were enrolled, followed by average age (36 +/- 11) years, mean duration after transplantation (4.3 +/- 2.1) months, mean course of disease (4.5 +/- 1.8) days. CT performance after admission revealed diffuse alveolar exudates and consolidation in all patients, and others still showed focal emphysema. With effective treatment, CT performance showed resolution of lung opacities completely until the second month, just little fiber remained. The pulmonary dysfunction showed apparent restrictive ventilatory abnormal and decreased DLco. Pulmonary dysfunction improved in the coming 3 - 4 weeks, and all dysfunction became complete resolution by the third month.


CONCLUSIONS
The characteristic CT performance was focused on the alveolar, with exudates, consolidation and focal emphysema. The main pulmonary dysfunction showed restrictive ventilatory abnormality and decreased DLco. Under effective therapy, these abnormalities would improve significantly by the third month.
Li
Yu-Ping
YP
Department of Respiration, First Affiliated Hospital to Wenzhou Medical College, Wenzhou 325000, China.
Chen
Cheng-Shui
CS
Ye
Min
M
Zhen
Shao-Ling
SL
Zhou
Ying
Y
Chen
Shao-Xian
SX
D000328:Adult; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011184:Postoperative Period; D012123:Pulmonary Ventilation; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed / Q000379:methods*