title: Tetramic and tetronic acids: an update on new derivatives and biological aspects.
abstract: Significant developments in the isolation of tetramic acids and tetronic acids, in the elucidation of their biosyntheses and their biological activities and in laboratory syntheses are reviewed with a focus on those derivatives with medicinal and pharmacological relevance. Important new members of the title compound families isolated since the year 2000 are covered as well as new biological aspects of some earlier congeners.
authors.affiliation: Organic Chemistry Laboratory, University of Bayreuth, Bayreuth, Germany. Rainer.Schobert@uni-bayreuth.de
authors.forename: Rainer
authors.initials: R
authors.lastname: Schobert
authors.forename: Andrea
authors.initials: A
authors.lastname: Schlenk
mesh_terms: D000818:Animals; D001695:Biology; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D010455:Peptides / Q000737:chemistry; D011760:Pyrrolidinones / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D005663:Furans; D010455:Peptides; D011760:Pyrrolidinones; C009435:tetramic acid; C003422:tetronic acid