title: Fatigue in multiple sclerosis presenting as acute relapse: subjective and objective assessment.
abstract: We report on a patient with multiple sclerosis (MS) who presented with fatigue as the only manifestation of an acute MS relapse. Fatigue was assessed by the 'Würzburg Fatigue Inventory in MS (WEIMuS)' scale and confirmed by neuropsychological testing of attention. After high-dose corticosteroid therapy, subjective symptoms were completely abolished. The improvement was corroborated by both, the WEIMuS score and neuropsychological testing. MS-related fatigue may be the only symptom of an acute MS relapse, and neuropsychological methods may be used to objectively assess and follow the time course of this common and disabling symptom.
authors.affiliation: Neurological Rehabilitation Center Quellenhof, D-75323 Bad Wildbad, Germany. peter.flachenecker@quellenhof.de
authors.forename: Peter
authors.initials: P
authors.lastname: Flachenecker
authors.forename: Heike
authors.initials: H
authors.lastname: Meissner
mesh_terms: D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005221:Fatigue / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D009483:Neuropsychological Tests; D012008:Recurrence
chemical_list: D000305:Adrenal Cortex Hormones