title: Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.
abstract: A 72 year-old man. He was diagnosed with rheumatoid arthritis in 2002. In January 2005 he noted productive cough and fever; he was diagnosed as eosinophilic pneumonia (EP). We discontinued administration of bucillamine and methotrexate and started to treat with oral prednisolone 30 mg daily. To rule out drug-induced EP, prednisolone was tapered by 10 mg per week. Consolidation occurred in the right lower lobe when prednisolone was decreased to 5 mg daily. After increasing the dose of prednisolone to 30 mg daily again, consolidation was promptly resolved. It was considered to be important to rule out drug-induced EP.
authors.affiliation: Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine. tanbo@med3.m.kanazawa-u.ac.jp
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tambo
authors.forename: Masaki
authors.initials: M
authors.lastname: Fujimura
authors.forename: Masahide
authors.initials: M
authors.lastname: Yasui
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kasahara
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Nakatsumi
authors.forename: Shinji
authors.initials: S
authors.lastname: Nakao
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D003545:Cysteine / Q000031:analogs & derivatives / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000139:chemically induced / Q000175:diagnosis* / Q000209:etiology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D005938:Glucocorticoids; D011239:Prednisolone; D003545:Cysteine; C026535:bucillamine; D008727:Methotrexate