title: [Evaluation of the efficacy of wiferon and arbidol in adult influenza].
abstract: The therapeutic efficacy of wiferon (recombinant alpha2beta-interferon) versus arbidol was studied in a double-blind controlled study in patients with laboratorily verified influenza. Within the first 24-36 hours after the onset of the disease, wiferon and arbidol reduced the duration of fever, intoxication, and the catarrhal symptoms of the disease as a whole. The agents were shown to have an immunomodulating effect.
authors.forename: L V
authors.initials: LV
authors.lastname: Kolobukhina
authors.forename: V V
authors.initials: VV
authors.lastname: Malinovskaia
authors.forename: R Z
authors.initials: RZ
authors.lastname: Gatich
authors.forename: L N
authors.initials: LN
authors.lastname: Merkulova
authors.forename: E I
authors.initials: EI
authors.lastname: Burtseva
authors.forename: E I
authors.initials: EI
authors.lastname: Isaeva
authors.forename: O V
authors.initials: OV
authors.lastname: Parshina
authors.forename: T S
authors.initials: TS
authors.lastname: Guseva
authors.forename: T G
authors.initials: TG
authors.lastname: Orlova
authors.forename: F V
authors.initials: FV
authors.lastname: Voronina
mesh_terms: D000285:Administration, Rectal; D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003371:Cough / Q000188:drug therapy; D004311:Double-Blind Method; D005334:Fever / Q000188:drug therapy; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007251:Influenza, Human / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage / Q000627:therapeutic use*; D007372:Interferons / Q000096:biosynthesis / Q000097:blood; D007962:Leukocytes / Q000276:immunology / Q000378:metabolism; D018655:Lymphocyte Count; D008875:Middle Aged; D011994:Recombinant Proteins; D012220:Rhinitis / Q000188:drug therapy; D013488:Suppositories / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D013440:Sulfides
chemical_list: D000998:Antiviral Agents; D007211:Indoles; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007372:Interferons; D011994:Recombinant Proteins; D013488:Suppositories; C086979:umifenovir; D013440:Sulfides