title: Examining the validity of autism spectrum disorder subtypes.
abstract: The classification of autism spectrum disorders (ASDs) is a topic of debate among clinicians and researchers with many questioning the validity of the distinction among subtypes. This manuscript examines the validity of three ASD subtypes (Autism, Asperger's, and PDDNOS) by reviewing 22 studies published between 1994 and 2006. We reviewed studies that examined differences between the subtypes in terms of clinical and demographic characteristics, neuropsychological profiles, comorbidity, and prognosis. Results largely did not support differences between autism and Asperger's disorder based on current diagnostic criteria. Overall, the most salient group differences were noted when samples were categorized on IQ. Drawing definitive conclusions is difficult due to the inconsistent application of diagnostic criteria and circularity in methods.
authors.affiliation: Department of Psychology and Nisonger Center, Ohio State University, 305 McCampbell Hall, 1581 Dodd Drive, Columbus, OH 43210-1257, USA.
authors.forename: Andrea N
authors.initials: AN
authors.lastname: Witwer
authors.forename: Luc
authors.initials: L
authors.lastname: Lecavalier
mesh_terms: D020817:Asperger Syndrome / Q000175:diagnosis / Q000523:psychology; D001321:Autistic Disorder / Q000145:classification* / Q000175:diagnosis / Q000523:psychology; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology; D015897:Comorbidity; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D015203:Reproducibility of Results