title: Ten-membered lactones from Phomopsis sp., an endophytic fungus of Azadirachta indica.
abstract: Four new 10-membered lactones ( 1- 4) and one known one ( 5) were isolated from the broth extract of an endophytic fungus, Phomopsis sp., obtained from the stem of Azadirachta indica. Their structures were assigned by analysis of spectroscopic data, and the structures of 1 and 4 were also confirmed by X-ray analysis. Compounds 1- 5 were tested for antifungal activity against several plant pathogens. Compound 4 demonstrated antifungal activity in the MIC value range 31.25-500 microg/mL.
authors.affiliation: Yunnan Institute of Microbiology and Laboratory Center, Yunnan University, Kunming 650091, People's Republic of China. shwu123@126.com.
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Wu
authors.forename: You-Wei
authors.initials: YW
authors.lastname: Chen
authors.forename: Shi-Cheng
authors.initials: SC
authors.lastname: Shao
authors.forename: Li-Dong
authors.initials: LD
authors.lastname: Wang
authors.forename: Zhi-Ying
authors.initials: ZY
authors.lastname: Li
authors.forename: Li-Yuan
authors.initials: LY
authors.lastname: Yang
authors.forename: Shao-Lan
authors.initials: SL
authors.lastname: Li
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
mesh_terms: D031601:Azadirachta / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure
chemical_list: D007783:Lactones