A Caenorhabditis elegans genetic-interaction map wiggles into view.
Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation.
Gunsalus
Kristin C
KC
Center for Genomics and Systems Biology and Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA. kcg1@nyu.edu
D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D029742:Caenorhabditis elegans Proteins / Q000235:genetics* / Q000378:metabolism; D049751:Genome, Helminth; D025941:Protein Interaction Mapping / Q000379:methods*; D015398:Signal Transduction
D029742:Caenorhabditis elegans Proteins