Hippocampal sclerosis and status epilepticus: cause or consequence? A MRI study.
Transient imaging abnormalities, including changes on diffusion-weighted imaging (DWI), may be seen in status epilepticus. These abnormalities can be followed by hippocampal sclerosis.



We report a 15-year-old lady with focal non convulsive status epilepticus (NCSE) and focal slowing on EEG. DWI exhibited abnormal hyperintense signals in bilateral temporal and insular cortices. After 3 weeks, MRI performed a localizated hippocampal atrophy.



The MRI findings indicated vasogenic and cytotoxic edema during seizure activity and subsequent loss of brain parenchyma.
Kuster
Gustavo Wruck
GW
Department of Neurology, University of São Paulo, São Paulo, SP, Brazil. gwkuster@hotmail.com
Braga-Neto
Pedro
P
Santos-Neto
Denizart
D
Garcia Santana
Maria Teresa
MT
Maia
Antonio Carlos Martins
AC
Povoas Barsottini
Orlando Graziani
OG
D000293:Adolescent; D001284:Atrophy / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D005260:Female; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D012598:Sclerosis / Q000150:complications / Q000473:pathology; D013226:Status Epilepticus / Q000150:complications / Q000473:pathology*