title: Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients.
abstract: METHODS
  Original article.
  
  
  OBJECTIVE
  To test the use of bornaprine in the hyperhidrosis treatment in the acute phase of spinal cord-injured patients.
  
  
  METHODS
  Patients with acute spinal cord lesions in the Spinal Unit of Pietra Ligure, Savona, Italy.
  
  
  METHODS
  In 4 years, 12 patients have been treated, for a maximum period of 75 days, with dosages ranging from 2 to 4 mg day(-1).
  
  
  RESULTS
  All of them reported long-lasting subjective benefits, without side effects, even after the interruption of the therapy.
  
  
  CONCLUSIONS
  The bornaprine treatment, at 2 or 4 mg day(-1) dosage, has been effective and safe to contrast hyperhidrosis, in the acute phase of spinal cord-injured patients. This positive experience would require additional trials and a larger number of cases to gain a more solid support.
authors.affiliation: Department of Rehabilitation, Spinal Cord Injury Unit, Santa Corona Hospital, Pietra Ligure, Savona, Italy. roberto.sergi@ospedalesantacorona.it
authors.forename: R
authors.initials: R
authors.lastname: Sergi
authors.forename: A
authors.initials: A
authors.lastname: Massone
authors.forename: S
authors.initials: S
authors.lastname: Moretto
authors.forename: C
authors.initials: C
authors.lastname: Oggerino
authors.forename: F
authors.initials: F
authors.lastname: Bertolotto
authors.forename: L
authors.initials: L
authors.lastname: Losio
authors.forename: M
authors.initials: M
authors.lastname: Ottonello
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001952:Bridged-Ring Compounds / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000209:etiology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D013119:Spinal Cord Injuries / Q000150:complications* / Q000188:drug therapy
chemical_list: D001952:Bridged-Ring Compounds; C006088:bornaprine