title: Giant neglected ameloblastoma: single stage treatment and clinicopathological review.
abstract: Giant ameloblastomas may present with massive swelling of the jaws. We report a giant ameloblastoma of the mandible in a Nigerian patient that measured 15.1x12.2x13.6cm and was managed with a single procedure. The tumour was removed by segmental mandibulectomy and reconstructed with a fibular free flap. The excess soft tissue was treated with a bilateral commissuroplasty. Single stage treatment that establishes early functional and aesthetic recovery offers advantages over multi staged procedures, and is therefore the treatment of choice for giant ameloblastomas.
authors.affiliation: Head & Neck Unit, University College London Hospitals, 250 Euston Road, London, NW1 2PG, United Kingdom. nicholas.kalavrezos@uclh.nhs.uk
authors.forename: Nicholas
authors.initials: N
authors.lastname: Kalavrezos
authors.forename: David James
authors.initials: DJ
authors.lastname: Baldwin
authors.forename: D Murray
authors.initials: DM
authors.lastname: Walker
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000473:pathology / Q000601:surgery*; D016025:Bone Transplantation; D005260:Female; D006801:Humans; D008334:Mandible / Q000601:surgery; D008339:Mandibular Neoplasms / Q000473:pathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation; D013524:Surgical Flaps