[Efficacy and safety of Fufang Biejia Ruangan tablet in patients with chronic hepatitis B complicated with hepatic fibrosis].
OBJECTIVE
To study the clinical therapeutic effects and safety of Fufang Biejia Ruangan tablet (FBRt) in patients with chronic hepatitis B complicated with hepatic fibrosis.


METHODS
Totally 420 patients were randomly divided into two groups, FBRt group (300 cases) were treated with Fufang Biejia Ruangan tablets and control group (120 cases) were treated with He Luo Shu Gan capsule, the patients in both groups were treated for 6 months.


RESULTS
The cure rate and total effective rate of FBRt group were significantly higher than those of control group (55.67 percent and 81.67 percent vs. 15.8 percent and 60.00 percent, P less than 0.01).


CONCLUSIONS
Fufang Biejia Ruangan tablet could alleviate clinical symptoms and hepatic fibrosis. Fufang Biejia Ruangan tablet is effective and safe in treatment of patients with chronic hepatitis B complicated with liver fibrosis.
Chen
Ju-mei
JM
The No. 302 Hospital of the Chinese People's Liberation Army, Beijing 100039, China.
Yang
Yong-ping
YP
Chen
De-yong
DY
Han
Jin
J
Jin
Xue-yuan
XY
Huang
Ze-xiang
ZX
Xu
Cheng-bin
CB
Shen
Yan-ming
YM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D019694:Hepatitis B, Chronic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology / Q000503:physiopathology; D008103:Liver Cirrhosis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D013607:Tablets
D013607:Tablets; D000410:Alanine Transaminase