title: [Molecular mechanisms for intracellular parasitisation and exclusion in macrophage infected with Mycobacterium leprae].
abstract: It was previously demonstrated that TLR2 and CORO1A (TACO, Coronin 1, p57) localize phagosome membrane of macrophage. However, the functional relationship between TLR2 and CORO1A was not known. We show here that there is a functional counteraction between TLR2 and CORO1A.
authors.affiliation: Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan. tanigawa@nih.go.jp
authors.forename: Kazunari
authors.initials: K
authors.lastname: Tanigawa
authors.forename: Koichi
authors.initials: K
authors.lastname: Suzuki
authors.forename: Akira
authors.initials: A
authors.lastname: Kawashima
authors.forename: Masayo
authors.initials: M
authors.lastname: Mishima
authors.forename: Huhehasi
authors.initials: H
authors.lastname: Wu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Akama
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Takeshita
authors.forename: Norihisa
authors.initials: N
authors.lastname: Ishii
mesh_terms: D002478:Cells, Cultured; D006801:Humans; D007918:Leprosy / Q000235:genetics / Q000382:microbiology; D008264:Macrophages / Q000276:immunology* / Q000382:microbiology*; D008840:Microfilament Proteins / Q000502:physiology*; D009166:Mycobacterium leprae; D010588:Phagosomes / Q000235:genetics; D015398:Signal Transduction / Q000502:physiology; D012867:Skin / Q000166:cytology; D051195:Toll-Like Receptor 2 / Q000502:physiology*
chemical_list: D008840:Microfilament Proteins; D051195:Toll-Like Receptor 2; C072061:coronin proteins