title: Steroidal glycosides from the roots of Cynanchum amplexicaule Sieb. et Zucc.
abstract: Seven new steroidal glycosides (amplexicosides A (4), B (7), C (8), D (9), E (10), F (11), and G (12)), along with six known compounds (cynatratoside A (1), tylophoside A (2), cynatratoside B (3), glaucogenin A (5), glaucoside A (6), and hancoside A (13)) were isolated from the 95% ethanol extract of the roots of Cynanchum amplexicaule (Sieb. et Zucc.). Their structures were determined based on spectral and chemical evidence. Compound 12 has a 14, 15-secopregnane-type skeleton aglycone, which has not been reported in literature.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, People's Republic of China.
authors.forename: Huan
authors.initials: H
authors.lastname: Chen
authors.forename: Nan
authors.initials: N
authors.lastname: Xu
authors.forename: Yuzhi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Li
authors.initials: L
authors.lastname: Qiao
authors.forename: Jiaqing
authors.initials: J
authors.lastname: Cao
authors.forename: Yao
authors.initials: Y
authors.lastname: Yao
authors.forename: Huiming
authors.initials: H
authors.lastname: Hua
authors.forename: Yuehu
authors.initials: Y
authors.lastname: Pei
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D031105:Cynanchum / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D013256:Steroids