Pallidal deep brain stimulation in the treatment of Meige syndrome.
BACKGROUND
Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published.


RESULTS
We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished.


CONCLUSIONS
The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.
Blomstedt
P
P
Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden. patric.blomstedt@neuro.umu.se
Tisch
S
S
Hariz
M I
MI
D000328:Adult; D017668:Age of Onset; D001764:Blepharospasm / Q000209:etiology; D046690:Deep Brain Stimulation; D004421:Dystonia / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008538:Meige Syndrome / Q000150:complications / Q000503:physiopathology / Q000628:therapy*