Three-dimensional spectral-domain optical coherence tomography images of the retina in the presence of epiretinal membranes.
OBJECTIVE
To study the inner surface of the retina in the presence of epiretinal membranes (ERMs) using a prototype spectral-domain optical coherence tomography (SD-OCT) device.


METHODS
Small case series, performed in the Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, from August 2005 through December 2006.


METHODS
An 8-microm axial-resolution SD-OCT instrument was used to scan the eyes of patients diagnosed with ERM. The ERM and the internal limiting membrane (ILM) were segmented separately to evaluate the traction caused by the ERM on the retina. It was then possible to reconstruct the ILM and ERM surfaces in 3-dimensional space and to obtain corresponding retinal thickness maps.


RESULTS
SD-OCT B scans showed the points of attachment of the ERM to the ILM. Segmented surface maps of the ERM produced very smooth sheets, whereas those of the ILM presented wrinkles under and around the ERM.


CONCLUSIONS
SD-OCT revealed the geometry of retinal traction in eyes with ERM and may be useful in understanding further the pathologic features of these lesions.
Legarreta
John E
JE
Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 1638 NW 10th Avenue, Miami, FL 33136, USA.
Gregori
Giovanni
G
Knighton
Robert W
RW
Punjabi
Omar S
OS
Lalwani
Geeta A
GA
Puliafito
Carmen A
CA
D000368:Aged; D001485:Basement Membrane / Q000473:pathology; D003941:Diagnostic Techniques, Ophthalmological; D019773:Epiretinal Membrane / Q000175:diagnosis*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*