title: Implantation of the Artisan iris reconstruction intraocular lens in 5 children with aphakia and partial aniridia caused by perforating ocular trauma.
abstract: OBJECTIVE
  To describe the long-term clinical results of the implantation of the Artisan iris reconstruction IOL in 5 eyes of 5 children for aphakia and partial aniridia attributable to penetrating ocular trauma.
  
  
  METHODS
  The charts of 5 children were retrospectively reviewed. The nature and the extent of injury; age at IOL implantation; visual, refractive, and cosmetic outcome; endothelial cell density; and complications and subsequent surgical interventions were evaluated.
  
  
  RESULTS
  Mean follow-up period was 8.9 years (range, 4.9-12.4). Mean age at implantation of the Artisan iris reconstruction IOL was 9.5 years (range, 7.7-12.7). Visual acuity improved in 2 of 5 eyes, remained stable in 2 of 5 eyes, and decreased in 1 of 5 eyes. Complaints of photophobia were reduced, and a satisfactory cosmetic outcome was achieved in 3 of 5 patients. The mean spherical equivalent refraction error at last follow-up was -4.0 D. Mean endothelial cell loss when compared with the healthy fellow eye was 42%. Two cases were complicated by partial luxation of the IOL, one case by persistent anterior uveitis and secondary glaucoma. One eye developed a retinal detachment.
  
  
  CONCLUSIONS
  The Artisan iris reconstruction IOL is a treatment option for the treatment of aniridia and aphakia due to penetrating ocular trauma in children. We emphasize the high-risk characteristics of the eyes treated and the importance of careful patient selection in the outcome of the implantation of the Artisan iris reconstruction IOL.
authors.affiliation: Department of Ophthalmology, Academic Medical Centre, Amsterdam, the Netherlands. m.l.sminia@amc.uva.nl
authors.forename: Marije L
authors.initials: ML
authors.lastname: Sminia
authors.forename: Monica Th P
authors.initials: MT
authors.lastname: Odenthal
authors.forename: Nitza
authors.initials: N
authors.lastname: Gortzak-Moorstein
authors.forename: Liesbeth J J M
authors.initials: LJ
authors.lastname: Wenniger-Prick
authors.forename: Hennie J
authors.initials: HJ
authors.lastname: Völker-Dieben
mesh_terms: D015783:Aniridia / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D001035:Aphakia / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002648:Child; D015807:Eye Injuries, Penetrating / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007498:Iris / Q000293:injuries / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000295:instrumentation*; D007910:Lenses, Intraocular; D008297:Male; D011474:Prosthesis Design; D012029:Refraction, Ocular; D012189:Retrospective Studies; D013997:Time Factors; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D014792:Visual Acuity