Histamine receptor H4R-selective ligands influence the STAT6 Transcription Activation Domain (TAD) and the DNA-binding.
Michel
I
I
Institut für Umwelt und Gesundheit (IUG) and University of Applied Sciences, FB Oe, Biochemistry, Marquardstrasse 35, D-36039 Fulda, Germany.
Borck
H
H
McElligott
S
S
Krieg
C
C
Diel
F
F
D000328:Adult; D001562:Benzimidazoles / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D005260:Female; D006633:Histamine Antagonists / Q000378:metabolism; D006801:Humans; D007211:Indoles / Q000378:metabolism; D019169:Jurkat Cells; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008024:Ligands; D010879:Piperazines / Q000378:metabolism; D017434:Protein Structure, Tertiary; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*; D011968:Receptors, Histamine / Q000378:metabolism*; D000074040:Receptors, Histamine H4; D050800:STAT6 Transcription Factor / Q000235:genetics* / Q000378:metabolism; D015533:Transcriptional Activation
D001562:Benzimidazoles; C418607:HRH4 protein, human; D006633:Histamine Antagonists; D007211:Indoles; C506811:JNJ 10191584; D008024:Ligands; D010879:Piperazines; D043562:Receptors, G-Protein-Coupled; D011968:Receptors, Histamine; D000074040:Receptors, Histamine H4; D050800:STAT6 Transcription Factor; C494101:STAT6 protein, human; C484309:1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine; D004247:DNA