title: Emissive terbium probe for multiphoton in vitro cell imaging.
abstract: A polymeric terbium complex that can be excited by near-infrared excitation at 800 nm via multiphoton absorption processes has been synthesized. This complex has been demonstrated to show strong, observable, three-photon-induced f-f emission in cell imaging. In vitro studies carried out in three carcinoma cell lines (A549, HONE1, and HeLa) have been performed and shown to have low cytotoxicity. This complex is therefore a potential candidate for future infrared excitation imaging dyes.
authors.affiliation: Department of Chemistry, the University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
authors.forename: Ga-Lai
authors.initials: GL
authors.lastname: Law
authors.forename: Ka-Leung
authors.initials: KL
authors.lastname: Wong
authors.forename: Cornelia Wing-Yin
authors.initials: CW
authors.lastname: Man
authors.forename: Wing-Tak
authors.initials: WT
authors.lastname: Wong
authors.forename: Sai-Wah
authors.initials: SW
authors.lastname: Tsao
authors.forename: Michael Hon-Wah
authors.initials: MH
authors.lastname: Lam
authors.forename: Paul Kwan-Sing
authors.initials: PK
authors.lastname: Lam
mesh_terms: D002277:Carcinoma / Q000378:metabolism*; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods*; D008024:Ligands; D018613:Microscopy, Confocal / Q000295:instrumentation / Q000379:methods; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D017785:Photons; D011108:Polymers / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000295:instrumentation / Q000379:methods; D013725:Terbium / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D008024:Ligands; D009942:Organometallic Compounds; D011108:Polymers; D013725:Terbium