Determination methods for biologically active compounds by ultra-performance liquid chromatography coupled with mass spectrometry: application to the analyses of pharmaceuticals, foods, plants, environments, metabonomics, and metabolomics.
This review summarizes the determination methods for biologically active compounds, such as pharmaceuticals, agrochemicals, and biogenic amines, by ultra-performance liquid chromatography coupled with mass spectrometry. The typical applications using the method are also described in this study, together with the characteristics of the methods.
Toyo'oka
Toshimasa
T
Division of Bio-Analytical Chemistry, School of Pharmaceutical Sciences, and Global COE Program, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. toyooka@u-shizuoka-ken.ac.jp
D002853:Chromatography, Liquid / Q000379:methods*; D005504:Food Analysis / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000378:metabolism; D028321:Plant Preparations / Q000032:analysis; D010944:Plants / Q000737:chemistry* / Q000378:metabolism
D004364:Pharmaceutical Preparations; D028321:Plant Preparations