title: Survival curve and factors related to drainage during the first 24 h after total knee arthroplasty.
abstract: Routine use of drains in total knee arthroplasty (TKA) is controversial. The aim of this study is to define the hourly risk of bleeding in the first 24 h following TKA using a survival study, to detect factors that might modify this risk, and establish a predictive model. In a retrospective study including 112 knees, patients with a coagulation disorder, platelet disease, or anticoagulation treatment were excluded. The risk factors studied included anesthesia score of the American society of anesthesiologists (ASA), proteinemia, total volume of fluid drained, and the use of low molecular weight heparin. The Kaplan-Meier test, Mantel-Haenszel test, and Cox regression analysis were used for the statistical calculations. The results indicate that the drains used in TKA can be removed within the first 18 h with a high degree of safety and low risk of persistent bleeding. The evolution of postoperative bleeding was independent of the factors studied.
authors.affiliation: Hospital Vall d'Hebron, Pg Vall d'Hebron 119-129, Traumatología 2a planta, 08035, Barcelona, Spain. oscarares77@gmail.com
authors.forename: Oscar
authors.initials: O
authors.lastname: Ares-Rodriguez
authors.forename: Alejandro Hernadez
authors.initials: AH
authors.lastname: Martinez
authors.forename: Alberto Hernandez
authors.initials: AH
authors.lastname: Fernandez
authors.forename: Enric
authors.initials: E
authors.lastname: Castellet
authors.forename: Antonio Navarro
authors.initials: AN
authors.lastname: Quilis
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D019645:Arthroplasty, Replacement, Knee; D001810:Blood Volume; D004322:Drainage; D017984:Enoxaparin / Q000627:therapeutic use; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000628:therapy*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012306:Risk; D013997:Time Factors; D020246:Venous Thrombosis / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin; D006495:Heparin, Low-Molecular-Weight; C411345:bemiparin