Fabrication of a gold nanoparticles decorated carbon nanotubes based novel modified electrode for the electrochemical detection of glucose.
A modified electrode based on gold nanoparticles decorated multiwall carbon nanotubes (MWNTs), MWNT-Au(nano)-ME is fabricated. MWNTs are functionalized with 4-aminothiophenol and coated over the glassy carbon electrode. Further, Au nanoparticles are deposited into MWNTs coated GC electrode by electrochemical reduction of HAuCl4. Field emission transmission electron microscope (FETEM) image shows the formation of approximately 5 nm sized Au nanoparticles without any agglomeration on the MWNTs surface. Further, the presence of Au nanoparticles is confirmed through X-ray photoelectron spectroscopic (XPS) studies. The electrocatalytic activity of the MWNT-Au(nano)-ME towards the detection of glucose is investigated. MWNT-Au(nano)-ME shows enhanced current response than pristine MWNT-ME over the entire (+0.05 to +0.80 V) potential range. The modified electrode shows linear response to current with the concentration of glucose between 1 and 20 mM. Larger current responses to glucose oxidation are witnessed at +0.60 V than at +0.05 V. However, a large interference signal, reflecting the accelerated oxidation of electroactive interference is observed at +0.60 V. No overlapping signal from the interferents such as ascorbic acid, acetaminophen, and dopamine are observed at the MWNT-Au(nano)-ME at +0.05 V. Further, the MWNT-Au(nano)-ME shows high resistance to the toxictiy of chloride ions.
Maneshl
Kalayil Manian
KM
Department of Chemistry Graduate School, Kyungpook National University, Daegu 702-701, South Korea, South Korea.
Kim
Jun Heon
JH
Santhosh
Padmanabhan
P
Gopalan
Anantha Iyengar
AI
Lee
Kwang-Pill
KP
Kang
Hee-Dong
HD
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D008839:Microelectrodes; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D020099:Coated Materials, Biocompatible; D037742:Nanotubes, Carbon; D006046:Gold; D005947:Glucose