title: Stenting of the right ventricular outflow tract in the symptomatic infant with tetralogy of Fallot.
abstract: BACKGROUND
  Repair of neonatal tetralogy of Fallot (TOF) has low mortality. Debate continues regarding the initial management of cyanotic or duct-dependent infants with TOF and adverse risk factors. While repair can and has been performed in these patients, it is associated with increased morbidity.
  
  
  OBJECTIVE
  We review the effectiveness of right ventricular outflow tract (RVOT) stenting in the symptomatic young infant with TOF.
  
  
  METHODS
  Clinical, echocardiographic, angiographic and haemodynamic data were reviewed for nine patients who underwent 11 RVOT stenting procedures from October 1994 to August 2007.
  
  
  RESULTS
  The pulmonary valve was deemed unsalvageable in all patients (median valve diameter 3.7 mm (range 2.7-4.2), Z-score -6.7 (range -9.7 to -5.4). RVOT stenting improved arterial oxygen saturation from a median of 73% (60-85%) to 94% (90-98%) (p = 0.008). Median Z-score for the left pulmonary artery increased from -4.9 (-7.8 to -2.4) before stent implantation to -1.5 (-4.2 to -0.2) (p = 0.02) before surgical repair. Median Z-score for the right pulmonary artery increased from -3.7 (-6.8 to -1.9) to -0.8 (-2.5 to 0.1) (p = 0.008). Median Nakata index increased from 56 mm(2)/m(2) (21-77) to 150 mm(2)/m(2) (123-231) (p = 0.008). There were no procedural complications. Six patients have undergone successful repair. There were no deaths.
  
  
  CONCLUSIONS
  In the symptomatic young infant with TOF, stenting of the RVOT provides a safe and effective management strategy, improving arterial oxygen saturation and encouraging pulmonary artery growth.
authors.affiliation: The Cardiac Diagnostic and Interventional Unit, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Canada.
authors.forename: G
authors.initials: G
authors.lastname: Dohlen
authors.forename: R R
authors.initials: RR
authors.lastname: Chaturvedi
authors.forename: L N
authors.initials: LN
authors.lastname: Benson
authors.forename: A
authors.initials: A
authors.lastname: Ozawa
authors.forename: G S
authors.initials: GS
authors.lastname: Van Arsdell
authors.forename: D S
authors.initials: DS
authors.lastname: Fruitman
authors.forename: K-J
authors.initials: KJ
authors.lastname: Lee
mesh_terms: D003097:Collateral Circulation; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011651:Pulmonary Artery / Q000002:abnormalities / Q000254:growth & development / Q000601:surgery; D011664:Pulmonary Valve / Q000002:abnormalities / Q000601:surgery; D011666:Pulmonary Valve Stenosis / Q000601:surgery; D015607:Stents; D013771:Tetralogy of Fallot / Q000601:surgery*; D014694:Ventricular Outflow Obstruction / Q000601:surgery*