title: Toward the Total Synthesis of Scleritodermin A: Preparation of the C(1)-N(15) Fragment.
abstract: The synthesis of the C(1)-N(15) fragment of the marine natural product Scleritodermin A has been accomplished through a short and stereocontrolled sequence. Highlights of this route include the synthesis of the novel ACT fragment and the formation of the alpha-keto amide linkage by the use of a highly activated alpha, beta-ketonitrile.
authors.affiliation: Cátedra de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, UDELAR, Av. General Flores 2124, C. C. 1157, Montevideo, Uruguay.
authors.forename: Diver
authors.initials: D
authors.lastname: Sellanes
authors.forename: Eduardo
authors.initials: E
authors.lastname: Manta
authors.forename: Gloria
authors.initials: G
authors.lastname: Serra