Investigation on the lipid- and cholesterol-lowering abilities of biocellulose.
The present study investigated and compared the physicochemical properties as well as the hypolipidemic and hypocholesterolemic effects between plant cellulose and biocellulose. Biocellulose had higher water-holding and cation-exchange capacities than plant cellulose ( approximately 2- and 6-fold, respectively). The results showed that the administration of plant cellulose and biocellulose to hamsters effectively ( P < 0.05) decreased the concentrations of serum triglyceride (by 13.9-55.5%), serum total cholesterol (by 17.4-27.9%), serum low-density lipoprotein cholesterol (by 41.9-47.9%), liver total lipids (by 6.4-10.3%), and liver cholesterol (by 11.8-16.3%). Feeding plant cellulose and biocellulose also enhanced the excretion of total lipids (144-182%), cholesterol (136-203%), and bile acids (259-479%) in feces. The efficacy of biocellulose in lowering serum lipids and cholesterol in hamsters was significantly higher than that of plant cellulose. These results suggested that biocellulose could be a promising low-calorie bulking ingredient for the development of novel fiber-rich functional foods of different forms such as powder, gelatinous, or shred forms.
Chau
Chi-Fai
CF
Department of Food Science and Biotechnology, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan.
Yang
Pat
P
Yu
Chao-Ming
CM
Yen
Gow-Chin
GC
D000818:Animals; D002482:Cellulose / Q000008:administration & dosage* / Q000096:biosynthesis* / Q000737:chemistry; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002784:Cholesterol / Q000032:analysis / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood; D006224:Cricetinae; D041822:Gluconacetobacter xylinus / Q000378:metabolism*; D008055:Lipids / Q000032:analysis / Q000097:blood*; D008099:Liver / Q000737:chemistry; D008297:Male; D008647:Mesocricetus; D010944:Plants / Q000737:chemistry; D014280:Triglycerides / Q000097:blood
D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002482:Cellulose; D002784:Cholesterol