Treatment of aggressive angiomyxoma with aromatase inhibitor prior to surgical resection.
Aggressive angiomyxoma (AA) is a rare, locally infiltrating soft tissue tumor typically located in the genital tract of young, reproductive age women. Surgical excision has been the mainstay of treatment. Recently, gonadotropin-releasing hormone agonist therapy has been reported to decrease the size of estrogen-receptor positive AA. We present the first case of a postmenopausal woman treated with an aromatase inhibitor to shrink the size of tumor prior to surgical resection.
Giles
D L
DL
Department of Gynecologic Surgery, Mayo Clinic, Scottsdale, Arizona, USA. giles.dobie@mayo.edu
Liu
P T
PT
Lidner
T K
TK
Magtibay
P M
PM
D000368:Aged; D000730:Androstadienes / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D047072:Aromatase Inhibitors / Q000008:administration & dosage*; D002081:Buttocks; D005260:Female; D006801:Humans; D009232:Myxoma / Q000188:drug therapy* / Q000601:surgery; D020360:Neoadjuvant Therapy; D012983:Soft Tissue Neoplasms / Q000188:drug therapy* / Q000601:surgery
D000730:Androstadienes; D000970:Antineoplastic Agents; D047072:Aromatase Inhibitors; C056516:exemestane