title: Acute perioperative normovolaemic haemodilution in major maxillofacial surgery.
abstract: Extensive blood loss can occur when patients have major operations for head and neck neoplasia. The risks and costs of allogeneic blood transfusion have been well documented. Acute perioperative normovolaemic haemodilution (APNH) is a method of saving blood and autologous transfusion. The purpose of this study was to compare a group of patients having major head and neck operations who had APNH, with a historical group, to assess the need for allogeneic transfusion. Of the 21 patients who had APNH only one patient required allogeneic blood. In the historical group of 24 patients, 15 patients had required allogeneic blood (p=0.0001). APNH is an economic, safe and practical way of saving blood.
authors.affiliation: Department of Oral & Maxillofacial Surgery, Morriston Hospital, Swansea, South Wales, SA6 6NL, UK.
authors.forename: I R
authors.initials: IR
authors.lastname: Parkin
authors.forename: G A
authors.initials: GA
authors.lastname: Chiu
authors.forename: P A
authors.initials: PA
authors.lastname: Schwarz
authors.forename: S C
authors.initials: SC
authors.lastname: Hodder
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001804:Blood Transfusion, Autologous; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care