Direct oxidative amidation of aldehydes with anilines under mechanical milling conditions.
Oxone is found to be an effective oxidant for the oxidative amidation of aldehydes with anilines to furnish amides in a one-pot process under mechanical milling conditions.
Gao
Jie
J
Hefei National Laboratory for Physical Sciences at Microscale, Joint Laboratory of Green Synthetic Chemistry, Hefei, Anhui 230026, P R China.
Wang
Guan-Wu
GW
D000447:Aldehydes / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry*; D017276:Friction; D008278:Magnesium Sulfate / Q000737:chemistry; D015394:Molecular Structure; D009038:Motion; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction; D013464:Sulfuric Acids / Q000737:chemistry; D013696:Temperature
D000447:Aldehydes; D000577:Amides; D000814:Aniline Compounds; D016877:Oxidants; D013464:Sulfuric Acids; D008278:Magnesium Sulfate; C048813:potassium peroxymonosulfuric acid