Two new lanostane triterpenoids from Poria cocos.
Two new lanostane triterpenoids, 29-hydroxypolyporenic acid C (4) and 25-hydroxypachymic acid (5), together with three known compounds, ergosta-7,22-dien-3beta-ol (1), polyporenic acid C (2) and pachymic acid (3), were isolated from the 95% ethanolic extract of the sclerotium of Poria cocos (Schw.) Wolf. Their structures were determined by extensive spectroscopic analyses, including IR, UV, ESITOF-MS, HRESI-MS, 1D and 2D NMR data (1H NMR, 13C NMR, 1H-1H COSY, NOESY, HSQC and HMBC).
Zheng
Yan
Y
State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicine, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Yang
Xiu-Wei
XW
D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D020072:Polyporales / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D014315:Triterpenes