title: Two new sesquiterpenoids from the soft coral Sinularia polydactyla (Ehreberg).
abstract: Two new sesquiterpenoids, polydactins A (1) and B (2) and a known sesquiterpene, 10alpha-hydroxycadin-4-en-15-al (3), were isolated from the soft coral Sinularia polydactyla (Ehreberg). Their structures were determined mainly by spectroscopic methods. Polydactin A (1) showed moderate cytotoxic activities against human oral epidermoid carcinoma cell lines (KB) and human breast carcinoma (MCF) tumour cell lines (in vitro).
authors.affiliation: School of Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
authors.forename: Cui-Xian
authors.initials: CX
authors.lastname: Zhang
authors.forename: Chen-Chen
authors.initials: CC
authors.lastname: Zhu
authors.forename: Su-Jun
authors.initials: SJ
authors.lastname: Yan
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Su
authors.forename: Yong-Ju
authors.initials: YJ
authors.lastname: Liang
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Yang
authors.forename: Kang-Cheng
authors.initials: KC
authors.lastname: Zheng
authors.forename: Long-Mei
authors.initials: LM
authors.lastname: Zeng
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
chemical_list: D012717:Sesquiterpenes