title: Primary cutaneous adenoid cystic carcinoma.
abstract: Primary cutaneous adenoid cystic carcinoma is a rare, slow-growing malignancy first described by Boggio in 1975. This tumor characteristically consists of basophilic cells with a distinct adenoid or cribriform pattern in the mid to deep reticular dermis. Modified myoepithelial cells with prominent basement membrane material often surround true lumina. Definitive diagnosis relies on the characteristic histologic features and the exclusion of metastatic disease. We describe two patients who presented with painful papules of the scalp and were successfully treated with wide local excision.
authors.affiliation: Department of Dermatology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Naylor
authors.forename: Papri
authors.initials: P
authors.lastname: Sarkar
authors.forename: Clifford S
authors.initials: CS
authors.lastname: Perlis
authors.forename: Dilip
authors.initials: D
authors.lastname: Giri
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Gnepp
authors.forename: Leslie
authors.initials: L
authors.lastname: Robinson-Bostom
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000601:surgery / Q000648:ultrastructure*; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D012535:Scalp; D012878:Skin Neoplasms / Q000601:surgery / Q000648:ultrastructure*