Pallidal stimulation for pantothenate kinase-associated neurodegeneration dystonia.
Pantothenate kinase-associated neurodegeneration is associated with generalised dystonia and cognitive deterioration. Limited evidence suggests that pallidal deep brain stimulation improves physical functioning. This is a report of the assessment and treatment of a severely affected patient in whom pallidal deep brain stimulation improved both physical and psychosocial functioning. Implications for treatment are briefly discussed.
Isaac
C
C
Clinical Neuropsychology Services, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.
Wright
I
I
Bhattacharyya
D
D
Baxter
P
P
Rowe
J
J
D000293:Adolescent; D002648:Child; D003071:Cognition; D046690:Deep Brain Stimulation; D004421:Dystonia / Q000209:etiology / Q000628:therapy*; D005917:Globus Pallidus; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome