[Effects of sample size on the observed number of allele of 9 STR loci with various genetic data].
In the genetic study, the samples can greatly influence the analysis and interpretation of the genetic data obtained. Here we examined the effects of sample size on the observed number of allele of 9 STR loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D13S317, D5S818, D7S820) with 30 various population genetic data. The results show: the quantity of alleles and the quantity of samples was not obviously corresponding, while the populations with few samples had more allele observed. And there was no significant influence on the quantity of the allele observed when the quantity of the samples reached to a certain amount. H (heterozygosity) was up to a stable level when the quantity of sample was 50. Those who had low heterozygosity (such as TPOX) changed obviously with the quantity of samples, while those had high heterozygosity (such as FGA) changed a little with the quantity of samples.
Gao
Ya
Y
Faculty of Forensics, Xi'an Jiaotong University, Xi'an 710061, China. gaoya@mail.xjtu.edu.cn
Li
Sheng-Bin
SB
D000483:Alleles; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*