Periodontal morphological microcirculation in oral lichen planus.
This study aimed at evaluating possible differences in the vascular pattern (of periodontal mucosa microcirculation) between healthy patients and patients suffering from PLP (periodontal lichen planus). Fifty-four patients (27 patients suffering from PLP and 27 healthy patients) were examined by means of videocapillaroscopy. The following area was examined for each patient: periodontal mucosa corresponding to 1.1 and 2.1. The following parameters were analyzed on every capillaroscopic image: capillary loop length, loop diameter, capillary tortuosity, capillary density, avascular areas, possible microhaemorrhages, distinctive morphology. The results obtained using videocapillaroscopic software were subjected to statistical analysis. The following parameters showed statistically significant differences: density, loop length, total diameter. This study and the research carried out over two years (from 2004 to 2006) have allowed us to confirm the increase in capillary diameter and density in PLP patients compared to the control patients. Besides, a remarkable increase in capillary density has been shown, which indicates a strong angiogenetic activity in PLP patients.
Scardina
Giuseppe Alessandro
GA
Department of Oral Science, University of Palermo, Italy. scardina@odonto.unipa.it
Cacioppo
Antonino
A
Carini
Francesco
F
Ruggieri
Alessia
A
Valenza
Vincenzo
V
Messina
Pietro
P
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001808:Blood Vessels / Q000382:microbiology / Q000473:pathology*; D002196:Capillaries / Q000382:microbiology / Q000473:pathology; D018450:Disease Progression; D005260:Female; D005881:Gingiva / Q000098:blood supply* / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D017676:Lichen Planus, Oral / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000382:microbiology / Q000473:pathology*; D011237:Predictive Value of Tests