[Studies on factors influencing on ephedrine contents in Maxing Shigan decoction].
OBJECTIVE
To investigate the factors influencing on the ephedrine contents in different compositions of Maxingshigan decoction.


METHODS
Adopt mixed uniform design to dismantle recipes, employ the stepping regression analysis to deal with experimental statistics, use the partial correlational analysis to analyze the correlation coefficients and the results were validated.


RESULTS
The regressive equation was of significance, that is Y = 4.36719347 + 7.752707437X1 + 1.2557197041X3 (r = 0.85564, P = 0.0189). The main influencing factors on ephedrine content in Maxingshigan decoction were gypsum and amygdalin. The influent factor of amygdalin on ephedrine content had great significance, and gypsum had significance.


CONCLUSIONS
The collective effects of amygdalin and gypsum affect the content of ephedrine in Maxing Shigan decoction which the content-effect relationship was in direct correlation.
Liang
Guang-Yi
GY
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China. guangyi_liang@21cn.com
He
Zhu-Ying
ZY
Wu
Kong-Yun
KY
Jin
Feng-Yun
FY
Li
Xing
X
Feng
Hua
H
D000678:Amygdalin / Q000737:chemistry* / Q000302:isolation & purification; D002133:Calcium Sulfate / Q000737:chemistry*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D029790:Ephedra sinica / Q000737:chemistry*; D004809:Ephedrine / Q000032:analysis*; D029882:Glycyrrhiza uralensis / Q000737:chemistry; D041743:Herb-Drug Interactions; D008419:Materia Medica / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D027861:Prunus / Q000737:chemistry
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica; C530199:maxingshigan; D000678:Amygdalin; D004809:Ephedrine; D002133:Calcium Sulfate