[Evaluation of compliance with antiretroviral treatment in a cohort of 200 patients in Djibouti, 2005].
We determined the rate of compliance with antiretroviral therapy and investigated the factors that influence it among 86 HIV patients. Compliance ratio (number of tablets taken/number prescribed) was assessed by tablet count. The mean ratio of compliance was 92%. By tablet count, 77% of the patients were compliant (compliance ratio > or =90%). Non-compliance was significantly associated with side-effects, degree of confidentiality of the care centre and travelling. Compliance correlated significantly with viral load. In multivariate analysis, community support and level of education protected against non-compliance. Patients having already missed a dose and those dissatisfied with confidentiality had a 4 times greater risk of non-compliance.
Ahmed
A A
AA
Ministère de la Santé, Djibouti. ammarmed@yahoo.com
Katlama
C
C
Ghosn
J
J
Guiguet
M
M
Costagliola
D
D
D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects / Q000523:psychology; D029754:Catha; D003219:Confidentiality; D003430:Cross-Sectional Studies; D015730:Djibouti; D004522:Educational Status; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology / Q000821:virology; D006801:Humans; D008019:Life Style; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D012944:Social Support; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders / Q000150:complications; D011795:Surveys and Questionnaires; D019562:Viral Load
D019380:Anti-HIV Agents