One step cascade synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles.
A Lewis base-catalyzed three-component cascade reaction was developed for the synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles. More than 25 new (NH)-triazoles were prepared in good to excellent yields under mild conditions. The availability of the C-4 vinyl group allows easy conversion into other triazole derivatives.
Sengupta
Sujata
S
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.
Duan
Haifeng
H
Lu
Weibing
W
Petersen
Jeffrey L
JL
Shi
Xiaodong
X