title: Sensitized detection of inhibitory fragments and iterative development of non-peptidic protease inhibitors by dynamic ligation screening.
authors.affiliation: Leibniz Institute for Molecular Pharmacology, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
authors.forename: Marco Florian
authors.initials: MF
authors.lastname: Schmidt
authors.forename: Albert
authors.initials: A
authors.lastname: Isidro-Llobet
authors.forename: Michael
authors.initials: M
authors.lastname: Lisurek
authors.forename: Adeeb
authors.initials: A
authors.lastname: El-Dahshan
authors.forename: Jinzhi
authors.initials: J
authors.lastname: Tan
authors.forename: Rolf
authors.initials: R
authors.lastname: Hilgenfeld
authors.forename: Jörg
authors.initials: J
authors.lastname: Rademann
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D017934:Coronavirus / Q000201:enzymology; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D008024:Ligands; D008026:Ligation; D010447:Peptide Hydrolases; D011480:Protease Inhibitors / Q000737:chemistry*
chemical_list: D008024:Ligands; D011480:Protease Inhibitors; D010447:Peptide Hydrolases