title: Localized malignant mesenteric mesothelioma causing small bowel obstruction.
abstract: Malignant mesothelioma is an uncommon lethal neoplasm in the serous membrane in which peritoneal mesothelioma is a rarer form. Herein is reported a case of malignant mesothelioma presenting as a localized mass inside the mesentery causing focal luminal obstruction of the small intestine. The diagnosis of malignant mesothelioma was obtained on repeat double balloon endoscopic biopsy. Partial resection of the small intestine along with the mesentery was performed, followed by a course of chemotherapy. No relapse of the disease has been found in the 8 months' follow up radiologically. To the best of the authors' knowledge this is the first reported case of localized malignant mesothelioma arising inside the mesentery. Mesothelioma should be considered as the differential diagnosis when small bowel obstruction occurs with unknown primary neoplasm.
authors.affiliation: Laboratory of Pathology, Toyama University Hospital, Toyama, Japan.
authors.forename: Kishio
authors.initials: K
authors.lastname: Kuroda
authors.forename: Shin
authors.initials: S
authors.lastname: Ishizawa
authors.forename: Takahiko
authors.initials: T
authors.lastname: Kudo
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Uotani
authors.forename: Ayumu
authors.initials: A
authors.lastname: Hosokawa
authors.forename: Tomonori
authors.initials: T
authors.lastname: Tanaka
authors.forename: Haruhisa
authors.initials: H
authors.lastname: Kitano
authors.forename: Takashi
authors.initials: T
authors.lastname: Hori
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tsukada
authors.forename: Toshiro
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Junya
authors.initials: J
authors.lastname: Fukuoka
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D018572:Disease-Free Survival; D016099:Endoscopy, Gastrointestinal; D015622:Epithelioid Cells / Q000473:pathology; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D008297:Male; D008643:Mesentery / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D054363:Solitary Fibrous Tumor, Pleural / Q000150:complications / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D002945:Cisplatin; D000093542:Gemcitabine