title: Outcome of endoscopic balloon dilation of strictures after laparoscopic gastric bypass.
abstract: OBJECTIVE
  Stricture formation at the gastrojejunal anastomosis is a relatively common complication after laparoscopic Roux-en-Y gastric bypass (LRYGB). The objective of this study was to report the incidence of stomal strictures after LRYGB in our institution and report our experience with their management by endoscopic balloon dilatation.
  
  
  METHODS
  This is a retrospective study of 1012 patients who underwent LRYGB from January 2001 to May 2004. Patients with nausea and vomiting after the surgery, suspected of having gastrojejunal (GJ) anastomotic stricture, had upper endoscopy. Stomas less than 10 mm in diameter, or those not allowing passage of the scope were considered significant strictures and were treated with balloon dilations. Dilations were performed with a through-the-scope (TTS) balloon, with sizes ranging from 6 to 18 mm. The following data were collected from these patients: age, sex, body mass index (BMI), comorbidities, size of balloon catheter, time from surgery until symptoms onset, number of endoscopies needed to relief symptoms, and complications of the procedure.
  
  
  RESULTS
  Sixty-one patients (46 females and 15 males) were found to have anastomotic strictures, corresponding to an incidence of 6%. In total, 134 upper endoscopies were performed, with 128 dilatations. The average age was 41.7 years (range: 19-68 years); mean preoperative BMI was 45 kg/m(2) (range: 42-61 kg/m(2)). Mean time from surgery to symptoms onset was 2 months (range: 1-6 months). The number of dilations per patient was as follows: a single dilation in 28% of patients, two dilations in 33%, three dilations in 26%, four dilations in 11.5%, and five dilations in 1.5% of patients. All the patients responded to dilation without need for formal surgical revision. However, after balloon dilatation three patients (4.9%), all females, had bowel perforation by radiological criteria (free air on X-ray), which corresponded to 2.2% of all dilatations. The maximum balloon size used in this group was 13.5 mm. All three patients had exploratory laparoscopy without finding of perforation site. They were treated with bowel rest, intravenous antibiotics for 7 days, and drain placement. No factors were identified to predict a risk of perforation.
  
  
  CONCLUSIONS
  This is the largest study to evaluate the outcome of endoscopic dilatations of GJ strictures after RYGB. Endoscopic balloon dilation is a safe and effective treatment for anastomotic strictures. However, it carries a small risk of perforation. Further case studies are needed to determine risk factors for perforation and if the patients can be managed conservatively in this setting.
authors.affiliation: Department of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd, Weston, FL 33331, USA. uklejaa@ccf.org
authors.forename: Andrew
authors.initials: A
authors.lastname: Ukleja
authors.forename: Bianca B
authors.initials: BB
authors.lastname: Afonso
authors.forename: Ronnie
authors.initials: R
authors.lastname: Pimentel
authors.forename: Samuel
authors.initials: S
authors.lastname: Szomstein
authors.forename: Raul
authors.initials: R
authors.lastname: Rosenthal
mesh_terms: D000328:Adult; D000368:Aged; D000713:Anastomosis, Roux-en-Y; D002404:Catheterization / Q000009:adverse effects; D003251:Constriction, Pathologic / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D016099:Endoscopy, Gastrointestinal; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects* / Q000379:methods; D005767:Gastrointestinal Diseases / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D015994:Incidence; D007416:Intestinal Perforation / Q000209:etiology; D007583:Jejunum; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013270:Stomach; D016896:Treatment Outcome