title: Percutaneous and surgical treatment of pyogenic liver abscesses: observation over a 21-year period in 148 patients.
abstract: BACKGROUND
  Percutaneous drainage of pyogenic liver abscess has become first-line treatment. In the past surgical drainage was preferred in some centres.
  
  
  OBJECTIVE
  The aim of this retrospective study was to assess the effectiveness of percutaneous treatments and surgical drainage, in terms of treatment success, hospital stay and costs.
  
  
  METHODS
  Data of 148 patients (90 males; 58 females; mean age, 61 yrs; range, 30-86 yrs) were retrospectively analysed.
  
  
  METHODS
  Patients' outcomes, including the length of hospital stay, procedure-related complications, treatment failure and death, were recorded. Multiple logistic regression model was used for statistical analysis.
  
  
  RESULTS
  One hundred and four patients (83 with solitary and 21 with multiple abscesses) were treated percutaneously, either by needle aspiration (91 patients) or catheter drainage (13 patients) depending on the abscess's size, and 44 patients (30 with solitary and 14 with multiple abscesses) were treated surgically. There was no statistically significant difference in patients' demographics or abscess characteristics between groups. Hospital stay was longer, and costs were higher in patients treated surgically (p<0.001). There was statistically significant difference in morbidity rate between groups (p<0.001). No death occurred in both groups.
  
  
  CONCLUSIONS
  Percutaneous and surgical treatment of pyogenic liver abscesses are both effective, nevertheless percutaneous drainage carries lower morbidity and is cheaper.
authors.affiliation: Infectious and Tropical Diseases Division, IRCCS S. Matteo, University of Pavia, Pavia, Italy. ferraiol@tin.it
authors.forename: G
authors.initials: G
authors.lastname: Ferraioli
authors.forename: A
authors.initials: A
authors.lastname: Garlaschelli
authors.forename: D
authors.initials: D
authors.lastname: Zanaboni
authors.forename: R
authors.initials: R
authors.lastname: Gulizia
authors.forename: E
authors.initials: E
authors.lastname: Brunetti
authors.forename: F P
authors.initials: FP
authors.lastname: Tinozzi
authors.forename: C
authors.initials: C
authors.lastname: Cammà
authors.forename: C
authors.initials: C
authors.lastname: Filice
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004322:Drainage / Q000191:economics / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007902:Length of Stay; D046290:Liver Abscess, Pyogenic / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011677:Punctures; D012189:Retrospective Studies; D016896:Treatment Outcome