Ether-soluble resin glycosides from the roots of Ipomoea batatas.
Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataosides I and II have novel structures because the core simonic acid B was esterised with cinnamic acid for the first time, and three different substituent esterification groups in one resin glycoside is scarce. The absolute configuration of the aglycone was elucidated to be S by Mosher's method.
Yin
Yong-Qin
YQ
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Kong
Ling-Yi
LY
D002240:Carbohydrate Sequence; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004986:Ether / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D027723:Ipomoea batatas / Q000737:chemistry*; D008969:Molecular Sequence Data; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D018517:Plant Roots / Q000737:chemistry; D012116:Resins, Plant / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012995:Solubility; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
D006027:Glycosides; D012116:Resins, Plant; D004986:Ether