title: Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect".
authors.affiliation: Department of Chemistry, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA.
authors.forename: Jason M
authors.initials: JM
authors.lastname: Crawford
authors.forename: Anna L
authors.initials: AL
authors.lastname: Vagstad
authors.forename: Karen P
authors.initials: KP
authors.lastname: Whitworth
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Ehrlich
authors.forename: Craig A
authors.initials: CA
authors.lastname: Townsend
mesh_terms: D051080:Acyl-Carrier Protein S-Malonyltransferase / Q000378:metabolism; D005658:Fungi / Q000201:enzymology; D007700:Kinetics; D048630:Polyketide Synthases / Q000096:biosynthesis* / Q000737:chemistry / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D013379:Substrate Specificity
chemical_list: D048630:Polyketide Synthases; D051080:Acyl-Carrier Protein S-Malonyltransferase