title: Metabolic syndrome: an evolving concept.
abstract: Metabolic syndrome is a cluster of interrelated cardiometabolic risk factors that are associated with an increased risk for both type 2 diabetes and atherosclerotic cardiovascular disease. These risk factors include visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low HDL cholesterol), elevated blood pressure, dysglycemia (pre-diabetes or diabetes) and a prothrombotic and proinflammatory state. The condition is progressive, beginning with borderline risk factors, and worsens over time. Primary treatment is lifestyle therapy--weight loss, increased physical activity and antiatherogenic diet. But, as the metabolic syndrome progresses, drug therapy directed at individual risk factors may be needed.
authors.affiliation: Hospital de Santa Maria, Lisboa, Portugal.
authors.forename: Nuno
authors.initials: N
authors.lastname: Cortez-Dias
authors.forename: Susana
authors.initials: S
authors.lastname: Martins
authors.forename: Manuela
authors.initials: M
authors.lastname: Fiuza
mesh_terms: D006801:Humans; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000628:therapy