Methicillin-resistant and -susceptible Staphylococcus aureus sequence type 398 in pigs and humans.
Methicillin-resistant Staphylococcus aureus sequence type 398 (ST398 MRSA) was identified in Dutch pigs and pig farmers. ST398 methicillin-susceptible S. aureus circulates among humans at low frequency (0.2%) but was isolated in 3 human cases of bacteremia (2.1%; p = 0.026). Although its natural host is probably porcine, ST398 MRSA likely causes infections in humans.
van Belkum
Alex
A
University Medical Center Rotterdam, Rotterdam, the Netherlands.
Melles
Damian C
DC
Peeters
Justine K
JK
van Leeuwen
Willem B
WB
van Duijkeren
Engeline
E
Huijsdens
Xander W
XW
Spalburg
Emile
E
de Neeling
Albert J
AJ
Verbrugh
Henri A
HA
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State; D006801:Humans; D008712:Methicillin / Q000494:pharmacology*; D016106:Methicillin Resistance; D009426:Netherlands; D009666:Nose / Q000382:microbiology; D016273:Occupational Exposure; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D013211:Staphylococcus aureus / Q000145:classification* / Q000187:drug effects* / Q000235:genetics; D013552:Swine / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D008712:Methicillin