Statistical analysis of twin populations using dissimilarity measurements in hippocampus shape space.
By analyzing interpoint comparisons, we obtain significant results describing the relationship in "hippocampus shape space" of clinically depressed, high-risk, and control populations. In particular, our analysis demonstrates that the high-risk population is closer in shape space to the control population than to the clinically depressed population.
Park
Youngser
Y
Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USA. youngser@jhu.edu
Priebe
Carey E
CE
Miller
Michael I
MI
Mohan
Nikhil R
NR
Botteron
Kelly N
KN
D000328:Adult; D003627:Data Interpretation, Statistical; D003865:Major Depressive Disorder / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004200:Diseases in Twins / Q000175:diagnosis*; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity