title: Benzophenone C-glucosides from Polygala glomerata Lour.
abstract: Four new benzophenone C-glucosides, glomeratides A (1), B (2), C (3), and D (4), along with a known compound arrilanin G (5), have been isolated from the whole plant of Polygala glomerata Lour. Their structures were determined by extensive analyses of their spectral data. Compounds 1-5 showed hepatoprotective activities against d-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Chuang-Jun
authors.initials: CJ
authors.lastname: Li
authors.forename: Dong-Ming
authors.initials: DM
authors.lastname: Zhang
authors.forename: Shi-Shan
authors.initials: SS
authors.lastname: Yu
mesh_terms: D000818:Animals; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D010936:Plant Extracts / Q000737:chemistry; D031801:Polygala / Q000737:chemistry*; D051381:Rats; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001577:Benzophenones; D005960:Glucosides; D010936:Plant Extracts