title: Plant NB-LRR immune receptors: from recognition to transcriptional reprogramming.
abstract: Both plants and animals contain nucleotide-binding domain and leucine-rich repeat (NB-LRR)-type immune receptors that function during defense against pathogens. Unlike animal NB-LRRs that recognize general pathogen or microbe-associated molecular patterns (PAMPs or MAMPs), plant NB-LRR immune receptors have evolved the ability to specifically recognize a wide range of effector proteins from different pathogens. Recent research has revealed that plant NB-LRRs are incredibly adaptive in their ways of pathogen recognition and defense initiation. This review focuses on the remarkable variety of functions, recognition mechanisms, subcellular localizations, and host factors associated with plant NB-LRR immune receptors.
authors.affiliation: Department of Molecular, Cellular, and Developmental Biology, Yale University, 219 Prospect Street, New Haven, CT 06520-8103, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Caplan
authors.forename: Meenu
authors.initials: M
authors.lastname: Padmanabhan
authors.forename: Savithramma P
authors.initials: SP
authors.lastname: Dinesh-Kumar
mesh_terms: D054884:Host-Pathogen Interactions; D010940:Plant Proteins / Q000276:immunology*; D010944:Plants / Q000276:immunology*; D011971:Receptors, Immunologic
chemical_list: D010940:Plant Proteins; D011971:Receptors, Immunologic