title: Serum cholesterol-decreasing effect of heat-moisture-treated high-amylose cornstarch in cholesterol-loaded rats.
abstract: Rats were fed on a diet containing cholesterol (Chol) at a level corresponding to the standard Chol intake in humans, and the influence of heat-moisture-treated high-amylose cornstarch (HHA) on their serum Chol level was investigated. HHA decreased the serum level of Chol in rats fed on the diet containing 0.1% Chol, which corresponds to a Chol intake in humans of 800 mg/d, although the liver levels of Chol increased in these rats. HHA did not influence the fecal excretion of Chol/bile acids. It is possible that the decrease in serum Chol level in the rats fed on the high-Chol diet can be attributed to the promotion of Chol uptake in the liver.
authors.affiliation: Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Tokyo 156-8502, Japan. haruhideudagawa@ybb.ne.jp
authors.forename: Haruhide
authors.initials: H
authors.lastname: Udagawa
authors.forename: Chika
authors.initials: C
authors.lastname: Kitaoka
authors.forename: Tatsuaki
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kobayashi-Hattori
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Oishi
authors.forename: Soichi
authors.initials: S
authors.lastname: Arai
authors.forename: Toshichika
authors.initials: T
authors.lastname: Takita
mesh_terms: D000688:Amylose / Q000008:administration & dosage* / Q000494:pharmacology; D000818:Animals; D002784:Cholesterol / Q000032:analysis / Q000097:blood*; D005243:Feces / Q000737:chemistry; D006358:Hot Temperature; D006813:Humidity; D008099:Liver / Q000737:chemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013213:Starch
chemical_list: D013213:Starch; D000688:Amylose; D002784:Cholesterol