Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients.
METHODS
Original article.


OBJECTIVE
To test the use of bornaprine in the hyperhidrosis treatment in the acute phase of spinal cord-injured patients.


METHODS
Patients with acute spinal cord lesions in the Spinal Unit of Pietra Ligure, Savona, Italy.


METHODS
In 4 years, 12 patients have been treated, for a maximum period of 75 days, with dosages ranging from 2 to 4 mg day(-1).


RESULTS
All of them reported long-lasting subjective benefits, without side effects, even after the interruption of the therapy.


CONCLUSIONS
The bornaprine treatment, at 2 or 4 mg day(-1) dosage, has been effective and safe to contrast hyperhidrosis, in the acute phase of spinal cord-injured patients. This positive experience would require additional trials and a larger number of cases to gain a more solid support.
Sergi
R
R
Department of Rehabilitation, Spinal Cord Injury Unit, Santa Corona Hospital, Pietra Ligure, Savona, Italy. roberto.sergi@ospedalesantacorona.it
Massone
A
A
Moretto
S
S
Oggerino
C
C
Bertolotto
F
F
Losio
L
L
Ottonello
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001952:Bridged-Ring Compounds / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000209:etiology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D013119:Spinal Cord Injuries / Q000150:complications* / Q000188:drug therapy
D001952:Bridged-Ring Compounds; C006088:bornaprine