Occurrence of a germinoma 22 years after resection of a mature cerebral teratoma.
We present the rare case of a 31-year-old man who developed a germinoma 22 years after resection of a mature teratoma of the pineal region. The initial stereotactic biopsy showed a granulomatous inflammation, but no malignant cells. The correct diagnosis could only be confirmed in a second cerebral biopsy, allowing for proper treatment with radiation therapy. The need to consider metachronous germinoma in this setting is discussed.
Janzarik
Wibke G
WG
Department of Neurology, Neurocenter, University of Freiburg, Freiburg, Germany. wibke.janzarik@uniklinik-freiburg.de
Müller
Klaus
K
Lübbert
Michael
M
Spreer
Joachim
J
Trippel
Michael
M
Uhlig
Inge
I
Weiller
Cornelius
C
Rauer
Sebastian
S
D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery*; D018237:Germinoma / Q000473:pathology; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology; D013724:Teratoma / Q000601:surgery*