title: Reconstruction of a 4-cm human median nerve gap by including an autogenous nerve slice in a bioabsorbable nerve conduit: case report.
abstract: Nerve gaps up to 3 cm in length can be reconstructed in the human with a bioabsorbable nerve conduit; however, nerve gaps greater than 3 cm have not been reconstructible in animal models unless a neurotrophic factor, like cultured Schwann cells, was added to the nerve conduit. It is the purpose of this article to present the result of human nerve regeneration across a 4-cm nerve gap in the median nerve at the wrist when a slice of autogenous normal nerve was placed into the middle of a bioabsorbable nerve conduit.
authors.affiliation: Dellon Institute for Peripheral Nerve Surgery, Boston, MA, USA.
authors.forename: Virginia
authors.initials: V
authors.lastname: Hung
authors.forename: A Lee
authors.initials: AL
authors.lastname: Dellon
mesh_terms: D020341:Absorbable Implants; D002349:Carpal Tunnel Syndrome / Q000601:surgery; D005260:Female; D006801:Humans; D008475:Median Nerve / Q000293:injuries / Q000601:surgery*; D008875:Middle Aged; D009414:Nerve Growth Factors / Q000502:physiology; D009416:Nerve Regeneration / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology; D009463:Neuroma / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000601:surgery; D011100:Polyglycolic Acid; D011183:Postoperative Complications / Q000601:surgery; D019736:Prostheses and Implants; D012583:Schwann Cells / Q000502:physiology; D014182:Transplantation, Autologous
chemical_list: D009414:Nerve Growth Factors; D011100:Polyglycolic Acid