title: Novel treatment of atrophic rhinitis: early results.
abstract: The aim of this randomized control trial, performed at a tertiary referral hospital, was to compare the therapeutic effectiveness of two novel treatment modalities, oral rifampicin and submucosal placentrex injection, in randomly selected patients of primary atrophic rhinitis regarding objective, subjective and histopathological improvement. Patients treated with oral rifampicin showed most promising results regarding objective, subjective and histopathological improvement with maximum disease-free interval on regular follow-up as compared to submucosal placentrex injections.
authors.affiliation: Calcutta National Medical College, 24 Gorachand Road, Kolkata 700014, India. abhishekjaswal@rediffmail.com
authors.forename: Abhishek
authors.initials: A
authors.lastname: Jaswal
authors.forename: Avik Kumar
authors.initials: AK
authors.lastname: Jana
authors.forename: Biswajit
authors.initials: B
authors.lastname: Sikder
authors.forename: Tapan K
authors.initials: TK
authors.lastname: Nandi
authors.forename: Sanjoy Kumar
authors.initials: SK
authors.lastname: Sadhukhan
authors.forename: Anjan
authors.initials: A
authors.lastname: Das
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D001706:Biopsy; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage*; D010924:Placental Extracts / Q000008:administration & dosage*; D012222:Rhinitis, Atrophic / Q000188:drug therapy* / Q000473:pathology; D012293:Rifampin / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D019384:Nucleic Acid Synthesis Inhibitors; D010924:Placental Extracts; D012293:Rifampin