title: Serum chromium and gestational diabetes.
abstract: OBJECTIVE
  To prospectively assess if chromium levels are different in gestational diabetics than in nondiabetic pregnant women. Therapeutic options could exist if levels are different.
  
  
  METHODS
  We conducted a 2-year prospective, gestational cohort study. The cohort included newly diagnosed pregnant patients. Two blood samples were taken, the first at consent, the second at the time of diabetes screening.
  
  
  RESULTS
  Five hundred eighty patients entered the cohort. One hundred fifty-five were lost to follow up and 425 patients completed the study (396 nondiabetics and 29 diabetics). The patients with gestational diabetes were significantly older, with a family history of gestational diabetes, and were significantly more likely to have been a gestational diabetic in a previous pregnancy (P < 05). There was no significant difference between the 2 groups for chromium levels both at enrollment (0.15 +/- 0.06 ng/mL vs 0.14 +/- 0.03 ng/mL; P = .28) and during the second trimester (0.14 +/- 0.06 ng/mL vs 0.14 +/- 0.04 ng/mL; P = .82).
  
  
  CONCLUSIONS
  Serum chromium levels do not exhibit any significant variation between gestational diabetic women and nondiabetic women when assessed prospectively.
authors.affiliation: Bethesda Family Medicine Residency Program, Cincinnati, OH 45212, USA. Liverdoctor@yahoo.com
authors.forename: Scott E
authors.initials: SE
authors.lastname: Woods
authors.forename: Vivian
authors.initials: V
authors.lastname: Ghodsi
authors.forename: Amy
authors.initials: A
authors.lastname: Engel
authors.forename: Jeff
authors.initials: J
authors.lastname: Miller
authors.forename: Shama
authors.initials: S
authors.lastname: James
mesh_terms: D000328:Adult; D002857:Chromium / Q000097:blood*; D015331:Cohort Studies; D016640:Diabetes, Gestational / Q000097:blood*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D002857:Chromium