Metabolic syndrome: an evolving concept.
Metabolic syndrome is a cluster of interrelated cardiometabolic risk factors that are associated with an increased risk for both type 2 diabetes and atherosclerotic cardiovascular disease. These risk factors include visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low HDL cholesterol), elevated blood pressure, dysglycemia (pre-diabetes or diabetes) and a prothrombotic and proinflammatory state. The condition is progressive, beginning with borderline risk factors, and worsens over time. Primary treatment is lifestyle therapy--weight loss, increased physical activity and antiatherogenic diet. But, as the metabolic syndrome progresses, drug therapy directed at individual risk factors may be needed.
Cortez-Dias
Nuno
N
Hospital de Santa Maria, Lisboa, Portugal.
Martins
Susana
S
Fiuza
Manuela
M
D006801:Humans; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000628:therapy