title: Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21.
authors.affiliation: Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 124, 10623 Berlin, Germany.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Schneider
authors.forename: Simone
authors.initials: S
authors.lastname: Keller
authors.forename: Falko E
authors.initials: FE
authors.lastname: Wolter
authors.forename: Lars
authors.initials: L
authors.lastname: Röglin
authors.forename: Winfried
authors.initials: W
authors.lastname: Beil
authors.forename: Oliver
authors.initials: O
authors.lastname: Seitz
authors.forename: Graeme
authors.initials: G
authors.lastname: Nicholson
authors.forename: Christina
authors.initials: C
authors.lastname: Bruntner
authors.forename: Julia
authors.initials: J
authors.lastname: Riedlinger
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Fiedler
authors.forename: Roderich D
authors.initials: RD
authors.lastname: Süssmuth
mesh_terms: D039903:Actinobacteria / Q000737:chemistry; D000970:Antineoplastic Agents / Q000494:pharmacology*; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000235:genetics*; D005663:Furans; D015394:Molecular Structure; D009429:Netropsin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*; D015854:Up-Regulation / Q000187:drug effects*
chemical_list: D000970:Antineoplastic Agents; D050759:Cyclin-Dependent Kinase Inhibitor p21; D005663:Furans; D016159:Tumor Suppressor Protein p53; C529559:proximicin A; C529560:proximicin B; C529561:proximicin C; D009429:Netropsin; C039281:furan