title: [Case of agranulocytosis associated with thymoma].
abstract: A 75-year-old-woman had undergone extended thymectomy, right upper and middle lobe resection, and radiation therapy (40 Gy) for thymoma at the age of 63. She visited our hospital complaining of low grade fever, cough, anorexia and a sore throat. Peripheral blood count revealed agranulocytosis. Agranulocytosis associated with thymoma was diagnosed, because there were no other possible causes of agranulocytosis such as drugs, infection, recent radiation therapy, or bone marrow invasion. In spite of giving G-CSF, steroid therapy and immunosuppressants, she died of pneumonia caused by agranulocytosis. We consider that agranulocytosis is a very rare complication of thymoma.
authors.affiliation: Department of Respiratory Medicine, Ikegami Hospital.
authors.forename: Keita
authors.initials: K
authors.lastname: Sato
authors.forename: Satoko
authors.initials: S
authors.lastname: Nojiri
authors.forename: Takanori
authors.initials: T
authors.lastname: Numata
authors.forename: Akira
authors.initials: A
authors.lastname: Kinoshita
authors.forename: Shinji
authors.initials: S
authors.lastname: Sakaguchi
authors.forename: Sakae
authors.initials: S
authors.lastname: Homma
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000209:etiology* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D013945:Thymoma / Q000150:complications* / Q000628:therapy; D013953:Thymus Neoplasms / Q000150:complications*