title: Bipolar disorder and multiple sclerosis.
abstract: Bipolar disorder may be overrepresented in multiple sclerosis (MS) patients. Although research in this area is limited, studies assessing the nature of this association have focused on genetic aspects, adverse reaction to drugs and brain demyelinating lesions. Herein we report three patients with MS that also presented bipolar disorder. The coexistence of neurological and psychiatric symptoms in most MS relapses highlights the relevance of biological factors in the emergence of mood disorders in these patients.
authors.affiliation: Centro de Investigação em Esclerose Múltipla, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
authors.forename: Mariana Inés
authors.initials: MI
authors.lastname: Ybarra
authors.forename: Marcos Aurélio
authors.initials: MA
authors.lastname: Moreira
authors.forename: Carolina Reis
authors.initials: CR
authors.lastname: Araújo
authors.forename: Marco Aurélio
authors.initials: MA
authors.lastname: Lana-Peixoto
authors.forename: Antonio Lucio
authors.initials: AL
authors.lastname: Teixeira
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy