title: Influenza vaccination and the elderly: pandemic preparedness.
abstract: Seasonal influenza causes significant morbidity and mortality in the elderly, the very young and those with chronic illness, despite the availability of effective vaccines. The mortality and morbidity attributed annually to seasonal influenza are small in comparison to the potential mortality and morbidity of a novel highly pathogenic human influenza A virus strain. The current influenza A/H5N1 virus that has caused epidemics in poultry and is evolving to find new niches needs only to become more efficiently transmitted from human to human to cause the next pandemic. Vaccination is the intervention with the potential to save the most lives when a pandemic occurs. Pandemic awareness and preparedness are essential to decrease the predicted chaos, death and illness arising from the next influenza pandemic.
authors.affiliation: Divisions of General Internal Medicine and Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 59905, USA. mkasten@mayo.edu
authors.forename: Mary Jo
authors.initials: MJ
authors.lastname: Kasten
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Poland
mesh_terms: D000368:Aged; D004189:Disaster Planning / Q000379:methods*; D004196:Disease Outbreaks / Q000517:prevention & control; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control* / Q000635:transmission; D032541:Mass Vaccination / Q000379:methods; D014481:United States
chemical_list: D007252:Influenza Vaccines