A case of fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion.
BACKGROUND
A 58-year-old schizophrenic male who had been drinking at least 4-5 l of pure water every day for 30 years was admitted to a hospital with complaints of nausea, fatigue, and irregular, fluctuating fevers (up to 39 degrees C). He had previously been prescribed fluoxetine at a dose of 20 mg/day and had been using the drug for 28 days.


METHODS
Review of medical history, physical examination, blood analysis, urine analysis, chest radiography and abdominal ultrasound.


METHODS
Psychogenic polydipsia and fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion.


RESULTS
Fluid restriction and discontinuation of fluoxetine.
Ozturk
Savas
S
Department of Nephrology, Haseki Training and Research Hospital, Millet Cad, Haseki, Istanbul 34330, Turkey. savasozturkdr@yahoo.com
Ozsenel
Ekmel Burak
EB
Kazancioglu
Rumeyza
R
Turkmen
Aydin
A
D005473:Fluoxetine / Q000009:adverse effects* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors