title: Improved contrast ultrasound with tissue harmonic minimizing pulse.
abstract: We have computed predistorted pulses that minimize tissue harmonics to < -25 dB compared to fundamental over a 4-cm depth in the focal region using a Hankel transform-based algorithm. The results indicate their potential in achieving patient independent improvement in contrast with microbubbles using wideband ultrasonic transducers at high mechanical indices.
authors.forename: Kajoli B
authors.initials: KB
authors.lastname: Krishnan
authors.forename: Kai E
authors.initials: KE
authors.lastname: Thomenius
mesh_terms: D000465:Algorithms; D000818:Animals; D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D014463:Ultrasonography / Q000379:methods*
chemical_list: D003287:Contrast Media