Clinical characteristics associated with isolation of small-colony variants of Staphylococcus aureus and Pseudomonas aeruginosa from respiratory secretions of patients with cystic fibrosis.
During a 3-month period, small-colony variant phenotypes of both Staphylococcus aureus and Pseudomonas aeruginosa were isolated from respiratory secretions of 8.2% and 9.2%, respectively, of 98 patients with cystic fibrosis, particularly those with advanced pulmonary disease and prolonged antibiotic exposure.
Schneider
Michael
M
Institute for Infectious Diseases, University of Bern, Friedbuehlstr. 51, P.O. Box 61, CH-3010 Bern, Switzerland.
Mühlemann
Kathrin
K
Droz
Sara
S
Couzinet
Sabine
S
Casaulta
Carmen
C
Zimmerli
Stefan
S
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002353:Carrier State / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications*; D006801:Humans; D007223:Infant; D011552:Pseudomonas Infections / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology; D011550:Pseudomonas aeruginosa / Q000254:growth & development* / Q000302:isolation & purification; D012137:Respiratory System / Q000378:metabolism / Q000382:microbiology; D013203:Staphylococcal Infections / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology; D013211:Staphylococcus aureus / Q000254:growth & development* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents