title: Choledochal cysts in adults and their complications.
abstract: BACKGROUND
  Despite refinements in the management of choledochal cysts in children, an increasing number of patients present with ongoing symptoms in adult life. The aim of this study was to review the management of adult patients with choledochal cysts in a tertiary referral centre.
  
  
  METHODS
  A retrospective review was carried out of all adult patients presenting with choledochal cysts to this department between 1992 and 2000. Patient records were reviewed and detailed analyses were made of the clinical presentation, radiological and biochemical findings, anatomical anomalies, management, complications and outcomes.
  
  
  RESULTS
  Of 16 patients (12 women and 4 men; median age 23 years), 8 had undergone previous upper gastrointestinal operations before referral, including 5 who had had previous cyst drainage procedures. All patients underwent elective complete cyst excision with Roux-en-Y hepaticojejunostomy. There were no operative deaths and there was a low early postoperative morbidity rate (25%). There was no evidence of biliary malignancy in any cyst. During a median postoperative follow-up of 44 months, five patients (31%) continued to experience cholangitis and two of these required additional revisional procedures, but are now symptom-free.
  
  
  CONCLUSIONS
  Patients with choledochal cysts should be referred to specialised tertiary surgical units. Total choledochal cyst excision with Roux-en-Y hepaticojejunostomy is the treatment of choice. Patients with previous inadequate cyst excisional procedures should undergo revisional surgery, to reduce recurrent symptoms and the risk of developing cholangiocarcinoma.
authors.affiliation: Department of Clinical and Surgical Sciences (Surgery), University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, Scotland.
authors.forename: H D E
authors.initials: HD
authors.lastname: Atkinson
authors.forename: C P
authors.initials: CP
authors.lastname: Fischer
authors.forename: C H C
authors.initials: CH
authors.lastname: de Jong
authors.forename: K K
authors.initials: KK
authors.lastname: Madhavan
authors.forename: R W
authors.initials: RW
authors.lastname: Parks
authors.forename: O J
authors.initials: OJ
authors.lastname: Garden