Cobalt dinitrosoalkane complexes in the C-H functionalization of olefins.
The use of cobalt dinitrosoalkane complexes in the C-H functionalization of alkenes has been demonstrated. Reaction of a series of alkenes with Me4CpCo(CO)2 in the presence of NO generates intermediate cobalt dinitrosoalkane complexes that can be deprotonated alpha to the nitrosyl group and added to various Michael acceptors. The resultant products can then undergo retrocycloaddition reactions in the presence of the original alkene to regenerate the starting cobalt dinitrosoalkane complex and release the functionalized alkene.
Schomaker
Jennifer M
JM
Department of Chemistry, University of California, Berkeley, California 94720, USA.
Boyd
W Christopher
WC
Stewart
Ian C
IC
Toste
F Dean
FD
Bergman
Robert G
RG
D000473:Alkanes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D003035:Cobalt / Q000737:chemistry*; D008968:Molecular Conformation; D009603:Nitroso Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000473:Alkanes; D000475:Alkenes; D009603:Nitroso Compounds; D009942:Organometallic Compounds; D003035:Cobalt