Preliminary evaluation of anti-pyretic and anti-ulcerogenic activities of Sida cordifolia methanolic extract.
The anti-pyretic and anti-ulcerogenic properties of methanolic extract of Sida cordifolia aerial parts (MESC) were investigated in rats. Oral dose of 500 mg/kg MESC significantly reduced pyrexia induced by TAB vaccine. MESC exhibited significant anti-ulcerogenic effect against aspirin and ethanol induced damage. Both these properties were comparable to the reference drugs.
Philip
Binu K
BK
Department of Pharmacology and Environmental Toxicology, Dr. A. L. M. PGIBMS, University of Madras, Taramani Campus, Chennai-600113, India. bkphilip@rediffmail.com
Muralidharan
A
A
Natarajan
B
B
Varadamurthy
S
S
Venkataraman
S
S
D000284:Administration, Oral; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001241:Aspirin; D000431:Ethanol; D005334:Fever / Q000139:chemically induced / Q000517:prevention & control; D006801:Humans; D019660:Malvaceae; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control; D014612:Vaccines
D018712:Analgesics, Non-Narcotic; D000897:Anti-Ulcer Agents; D010936:Plant Extracts; D014612:Vaccines; D000431:Ethanol; D001241:Aspirin