title: Periprocedural complication rates are equivalent between symptomatic and asymptomatic patients undergoing carotid angioplasty and stenting.
abstract: Patients with neurologic symptoms who undergo carotid endarterectomy (CEA) have a higher incidence of stroke and death in the perioperative period than those with asymptomatic carotid disease. This study examines the outcomes of symptomatic and asymptomatic patients undergoing carotid stenting (CAS). From 2002 to 2006, 201 CAS procedures were performed in 193 patients (117 men, mean age 73 +/- 10 years), of whom 142 were for asymptomatic (AS) and 59 for symptomatic (S) disease. Preoperative neurologic symptoms included recent ipsilateral cerebrovascular accident (CVA, 29%), transient ischemic attack (50%), and amaurosis fugax (22%). There were 201 carotid stents placed (107 Acculink, 43 Wallstent, 23 Precise, 21 NexStent, 3 Exponent, 3 Xact, 1 Herculink) and 198 protection devices used (79 Accunet, 53 EPI Filterwire, 43 PercuSurge, 20 Angiogard, 3 EmboShield). Mean follow-up was 41 weeks. The groups were matched in terms of demographics and comorbidities (carotid artery disease, hypertension, hyperlipidemia, diabetes mellitus, peripheral vascular disease, smoking, and chronic obstructive pulmonary disease; p = nonsignificant [NS]). There was no significant difference in anatomic risk factors (neck irradiation, S 3%, AS 6%; prior CEA, S 14%, AS 14%; bovine arch, S 22%, AS 16%; p = NS), and the types of embolic protection devices and stents used were similar between groups. The mean percentages of preintervention carotid stenosis were equal (S 88%, AS 88%), and the technical success rate was 99%. Incidence rates of CVA (S 3.4%, AS 1.4%), myocardial infarction (S 1.7%, AS 1.4%), and death (S 0, AS 0.7%) were equivalent between groups (p = NS). CAS with cerebral protection can be performed safely in both symptomatic and asymptomatic patients. The presence of preoperative neurologic symptoms does not significantly increase the risk of adverse events in the perioperative period in this study.
authors.affiliation: Division of Vascular Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY, USA.
authors.forename: Soo J
authors.initials: SJ
authors.lastname: Rhee-Moore
authors.forename: Brian G
authors.initials: BG
authors.lastname: DeRubertis
authors.forename: Russell C
authors.initials: RC
authors.lastname: Lam
authors.forename: Robert L
authors.initials: RL
authors.lastname: Hynecek
authors.forename: Larisse
authors.initials: L
authors.lastname: Lee
authors.forename: James F
authors.initials: JF
authors.lastname: McKinsey
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Morrissey
authors.forename: John
authors.initials: J
authors.lastname: Karwowski
authors.forename: Leila
authors.initials: L
authors.lastname: Mureebe
authors.forename: K Craig
authors.initials: KC
authors.lastname: Kent
authors.forename: Peter L
authors.initials: PL
authors.lastname: Faries
mesh_terms: D000368:Aged; D020757:Amaurosis Fugax / Q000209:etiology; D016893:Carotid Stenosis / Q000150:complications / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000209:etiology; D008297:Male; D015607:Stents / Q000009:adverse effects*; D020521:Stroke / Q000209:etiology; D016896:Treatment Outcome