title: Infections of electrophysiologic cardiac devices.
abstract: Infections related to electrophysiologic cardiac device placement are increasing dramatically and are associated with adverse outcomes. With the US population aging and living longer, cardiac devices are utilized in an older population with significant comorbidities, making the threat from infectious complications significant. Electrophysiologic cardiac devices typically include an implanted pulse generator and an intravascular lead. Infection may occur at any component of the device, resulting in varied presentations. Bacteremia in cardiac device recipients may reflect primary generator pocket infection, or alternate sources of bacteremia may result in secondary hematogenous lead infection. This review focuses on the pathology, diagnosis, management and prevention of electrophysiologic cardiac device infections.
authors.affiliation: Division of Infectious Diseases, David Geffen School of Medicine at University of California, Los Angeles, 10833 LeConte Ave, 37-121 CHS, Los Angeles, CA 90095, USA. duslan@mednet.ucla.edu
authors.forename: Daniel Z
authors.initials: DZ
authors.lastname: Uslan
mesh_terms: D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D001424:Bacterial Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D004696:Endocarditis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D010138:Pacemaker, Artificial / Q000009:adverse effects* / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control