title: Necrotizing fasciitis caused by Pseudomonas aeruginosa.
abstract: An 85-year-old man patient was admitted to the hospital complaining of fever and bilateral leg pain with swelling and erythema. A laboratory investigation revealed leukocytopenia, thus suggesting sepsis. Gram negative rods were detected in the specimen from the affected skin and empiric antibacterial therapy was initiated. The following day, his symptoms worsened and Pseudomonas aeruginosa was isolated from the blood culture and the skin specimen. Magnetic resonance imaging (MRI) did not show the typical characteristics of necrotizing fasciitis. In spite of intensive medical treatment, the patient's condition became critical, and on day 10 after admission, he died of multiple organ failure. An autopsy revealed necrotizing fasciitis due to P. aeruginosa. This is a rare case and its clinical presentation was atypical. The clinical diagnosis of this infection may be difficult, and therefore such cases warrant the careful attention of physicians.
authors.affiliation: Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa. morikazu.akamine@nagohp.com
authors.forename: Morikazu
authors.initials: M
authors.lastname: Akamine
authors.forename: Kazuya
authors.initials: K
authors.lastname: Miyagi
authors.forename: Teruhito
authors.initials: T
authors.lastname: Uchihara
authors.forename: Masato
authors.initials: M
authors.lastname: Azuma
authors.forename: Satomi
authors.initials: S
authors.lastname: Yara
authors.forename: Futoshi
authors.initials: F
authors.lastname: Higa
authors.forename: Shusaku
authors.initials: S
authors.lastname: Haranaga
authors.forename: Masao
authors.initials: M
authors.lastname: Tateyama
authors.forename: Akiko
authors.initials: A
authors.lastname: Matsuzaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakayama
authors.forename: Jiro
authors.initials: J
authors.lastname: Fujita
mesh_terms: D000369:Aged, 80 and over; D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000382:microbiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000382:microbiology; D011552:Pseudomonas Infections / Q000150:complications* / Q000175:diagnosis*; D011550:Pseudomonas aeruginosa / Q000472:pathogenicity*