Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment.
An original Hadamard-encoding scheme allows discrimination among seven amino acid types in a single two-dimensional NMR experiment. Combined with hyperdimensional NMR techniques, this presents a promising new method for fast, automated backbone resonance assignment of proteins in only a few hours time.
Lescop
Ewen
E
IBS, Institut de Biologie Structurale Jean-Pierre Ebel, 41 rue Jules Horowitz, F-38027 Grenoble, France.
Rasia
Rodolfo
R
Brutscher
Bernhard
B
D000596:Amino Acids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry*; D013997:Time Factors
D000596:Amino Acids; D011506:Proteins