title: Manganous phosphate acts as a superoxide dismutase.
abstract: A substantial body of evidence indicates that high intracellular concentrations of inorganic manganous ions render some cells resistant to ionizing radiation and provide substantial antioxidant protection to aerobic cells lacking superoxide dismutase (SOD) enzymes. We found that manganous phosphate is unique among those manganous salts studied in its ability to remove superoxide rapidly and catalytically from aqueous solution via a disproportionation mechanism that is entirely different from those of the SOD enzymes.
authors.affiliation: Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Barnese
authors.forename: Edith B
authors.initials: EB
authors.lastname: Gralla
authors.forename: Diane E
authors.initials: DE
authors.lastname: Cabelli
authors.forename: Joan Selverstone
authors.initials: JS
authors.lastname: Valentine
mesh_terms: D005720:Gamma Rays; D007700:Kinetics; D009942:Organometallic Compounds / Q000737:chemistry*; D011675:Pulse Radiolysis; D013482:Superoxide Dismutase / Q000737:chemistry*; D013481:Superoxides / Q000737:chemistry
chemical_list: D009942:Organometallic Compounds; D013481:Superoxides; D013482:Superoxide Dismutase; C406182:manganese phosphate