[Results of treatment in patients with destructive pulmonary tuberculosis without consideration of drug sensitivity in Mycobacterium tuberculosis].
Treatment of 63 patients having infiltrative and disseminated pulmonary tuberculosis attended by decay and bacterial excretion with 4 essential drugs (isoniazid, rifadine, pyrazinamide, ethambutol) and, in disseminated processes, additionally with streptomycin without determining their drug sensitivity contributed to the cessation of sputum acid-resistant mycobacteria in 96.8% and to cavity cicatrisation in 77.8%. Irregular use of izoniazid and rifadine during continued treatment is one of the reasons for the low rates of cavity resolution.
Abashev
I M
IM
Kozlova
A I
AI
Ivanova
L N
LN
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004342:Drug Hypersensitivity / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008168:Lung / Q000382:microbiology* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D010349:Patient Compliance / Q000706:statistics & numerical data; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology
D000995:Antitubercular Agents