title: Gliomatosis cerebri--an uncommon neuroepithelial tumor in children with oligodendroglial phenotype.
abstract: Gliomatosis cerebri(GC) is a highly aggressive, rare form of neuroepithelial tumor. Due to the diffuse nature of the tumor, its pathological grade is not conclusively established unless a biopsy is carried out from multiple sites. The tumor typically infiltrates the cortex in the subpial plane and also insinuates in the perineuronal space and around the Virchow-Robin spaces with relative preservation of the underlying brain parenchyma. Most of the previously reported cases of GC are astrocytic in nature. In this study, we report 2 pediatric patients of GC with oligodendroglial morphology on histopathological examination. In view of the rarity of the oligodendroglial phenotype of gliomatosis cerebri as well as the rare occurrence in children, we report these 2 cases.
authors.affiliation: Department of Pathology, Sanjay Gandhi Postgraduate, Institute of Medical Sciences, Lucknow, India. pal_lily@yahoo.co.uk
authors.forename: Lily
authors.initials: L
authors.lastname: Pal
authors.forename: Sanjay
authors.initials: S
authors.lastname: Behari
authors.forename: Shaleen
authors.initials: S
authors.lastname: Kumar
authors.forename: Raj
authors.initials: R
authors.lastname: Kumar
authors.forename: S K
authors.initials: SK
authors.lastname: Shankar
authors.forename: R K
authors.initials: RK
authors.lastname: Gupta
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D009837:Oligodendroglioma / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D010641:Phenotype; D035583:Rare Diseases