title: Autopsy case of rapid progressive atypical carcinoid of the lung discovered with multiple nodular shadows.
abstract: We report an autopsy case of rapid progressive atypical carcinoid of the lung discovered as multiple nodular shadows. The patient was an 82-year-old man with non-productive cough. Both chest radiography and computed tomography revealed multiple nodules in both the lung and pleural effusion. Multiple metastases to bone and liver were also noted. Samples from the wall-side pleural lesion were obtained by video-assisted thoracoscopic surgery under local anesthesia, and histological examination led to a diagnosis of atypical carcinoid. Treatment was ineffective and the patient died on day 39 after admission. The primary site was identified as the lung after autopsy. We believe that early detection is crucial in the treatment of atypical carcinoid due to poor prognosis.
authors.affiliation: Departments of Respiratory Medicine, National Hospital Organization, Kochi Hospital, Kochi, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okano
authors.forename: Mami
authors.initials: M
authors.lastname: Inayama
authors.forename: Nobuo
authors.initials: N
authors.lastname: Hatakeyama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hino
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Iwahara
authors.forename: Tokuji
authors.initials: T
authors.lastname: Motoki
authors.forename: Keishi
authors.initials: K
authors.lastname: Naruse
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yokota
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Ogushi
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001344:Autopsy; D001859:Bone Neoplasms / Q000556:secondary; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D008297:Male; D020775:Thoracic Surgery, Video-Assisted; D013997:Time Factors; D014057:Tomography, X-Ray Computed