title: Variation of a variation: case report of attenuated familial adenomatous polyposis.
abstract: BACKGROUND
  First described in 1988, attenuated familial adenomatous polyposis (AFAP) is a rare autosomal dominant precancerous condition of the gastrointestinal tract. Few reports have described adenocarcinomatous change in the gastroduodenal region thus far.
  
  
  METHODS
  We report a case of AFAP presenting with extensive gastric polyposis and ampullary adenocarcinoma in absence of a positive family history of gastrointestinal cancer and a novel mutation.
authors.affiliation: Institute of Liver Studies, King's College Hospital, London , UK.
authors.forename: P
authors.initials: P
authors.lastname: Bhatnagar
authors.forename: H
authors.initials: H
authors.lastname: Tetzlaff
authors.forename: L
authors.initials: L
authors.lastname: Izatt
authors.forename: J
authors.initials: J
authors.lastname: Devlin
authors.forename: N D
authors.initials: ND
authors.lastname: Heaton