[Pipamperone and the treatment of impulsive aggressive behaviour].
BACKGROUND
Pipamperone is prescribed to prevent impulsive aggressive behaviour in patients with intermittent explosive disorder, personality disorders or mental retardation.


OBJECTIVE
To investigate the scientific basis of this treatment.


METHODS
Various databases were searched using the terms 'pipamperon', 'pipamperone' and 'Dipiperon'. Located articles were reviewed in order to discover whether they dealt with the relationship between the drug and impulsiveness and aggression. results Six publications were found, all dating from before 1979.


CONCLUSIONS
In view of the limited amount of research on the subject and the adverse side effects it is concluded that pipamperone is not the drug of first choice considering the treatment of impulsive aggressive behaviour.
Klaassen
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aagklaassen@gmail.com <aagklaassen@gmail.com>
D000374:Aggression / Q000187:drug effects*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002090:Butyrophenones / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D007175:Impulsive Behavior / Q000188:drug therapy*; D015201:Meta-Analysis as Topic; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D002090:Butyrophenones; C005569:pipamperone