Arousal by stimulation of deep-brain nuclei.
Schiff et al. show that deep-brain stimulation of the unspecific thalamocortical system through certain midline thalamic nuclei produces an alerting effect in a patient in a minimally conscious state. Such nuclei include the central lateral nucleus, paralaminar regions of the median dorsalis, and the posterior-medial aspect of the centromedian/parafascicularis nucleus complex.
Staunton
Hugh
H
Department of Clinical Neurological Sciences, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland. hugh@iol.ie.
D001143:Arousal / Q000502:physiology*; D001364:Awareness / Q000502:physiology; D001930:Brain Injuries / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D003243:Consciousness / Q000502:physiology*; D046690:Deep Brain Stimulation; D006801:Humans; D011379:Prognosis; D013787:Thalamic Nuclei / Q000293:injuries / Q000473:pathology / Q000502:physiology*