Evaluation of the susceptibility trends to meropenem in a nationwide collection of clinical isolates in Japan: a longitudinal analysis from 2002 to 2006.
The meropenem susceptibility surveillance study was performed between 2002 and 2006 in Japan. Meropenem resistance against Pseudomonas aeruginosa was nearly constant at about 10% during the period. For all species of the bacteria tested, the MIC(90) of meropenem in 2006 was not more than 4-fold higher than that in 2002 and 2004.
Ishii
Yoshikazu
Y
Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143-8540, Japan. yoishii@med.toho-u.ac.jp
Yamaguchi
Keizo
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology; D006801:Humans; D007564:Japan; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D018571:Sentinel Surveillance; D013845:Thienamycins / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem