Problems in three Japanese drug users with Human Immunodeficiency Virus infection.
Numbers of individuals infected with Human Immunodeficiency Virus (HIV) are increasing in Japan. The majority of them are Men who have sex with men and a part of them take drugs as 'Sex drug' at their sexual intercourse. Especially, Amyl nitrite, Methamphetamine, 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DIPT; Foxy), and 3, 4-methylenedioxy- methamphetamine (MDMA; Ecstasy) are used, and they sometimes cause the physical and mental disorders. However, the actual drug inducing troubles among Japanese HIV-infected drug users had not yet been discussed enough. In this report, we describe three cases with HIV infection; a case developed severe neuroleptic malignant syndrome (NMS) after taking 5-MeO-DIPT, a case with persistent convulsion due to multiple drug intake and a case with rhabdomyolysis due to the non-subjective methamphetamine intake. Through these cases, we raise and discuss several underlying problems associated with drug use among HIV-infected individuals.
Kuwahara
Takeshi
T
Department of Pharmacy, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Nakakura
Takahiro
T
Oda
Sachiko
S
Mori
Masahiko
M
Uehira
Tomoko
T
Okamoto
Gaku
G
Yoshino
Munehiro
M
Sasakawa
Atsushi
A
Yajima
Keishiro
K
Umemoto
Aiko
A
Takada
Kiyonori
K
Makie
Toshio
T
Yamamoto
Yoshihiko
Y
D008735:5-Methoxytryptamine / Q000009:adverse effects / Q000031:analogs & derivatives; D000328:Adult; D000680:Amyl Nitrite / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active; D044466:Asian People; D004347:Drug Interactions; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000009:adverse effects; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D012206:Rhabdomyolysis / Q000209:etiology*; D012640:Seizures / Q000209:etiology*; D019966:Substance-Related Disorders / Q000150:complications*
C033696:5-methoxy-N,N-diisopropyltryptamine; D008735:5-Methoxytryptamine; D008694:Methamphetamine; D000680:Amyl Nitrite; D018817:N-Methyl-3,4-methylenedioxyamphetamine