title: Elevated substance P levels in HIV-infected women in comparison to HIV-negative women.
abstract: Substance P and its receptor (neurokinin-1R) are potent modulators of neuroimmunoregulation and HIV/AIDS infection. We previously demonstrated that HIV-seropositive men had significantly higher substance P levels compared to uninfected controls. We now demonstrate that substance P plasma levels are significantly higher in HIV-infected women in comparison to uninfected control women.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Joseph Stokes Jr. Research Institute at the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. DOUGLAS@email.chop.edu
authors.forename: Steven D
authors.initials: SD
authors.lastname: Douglas
authors.forename: Avital
authors.initials: A
authors.lastname: Cnaan
authors.forename: Kevin G
authors.initials: KG
authors.lastname: Lynch
authors.forename: Tami
authors.initials: T
authors.lastname: Benton
authors.forename: Huaqing
authors.initials: H
authors.lastname: Zhao
authors.forename: David R
authors.initials: DR
authors.lastname: Gettes
authors.forename: Dwight L
authors.initials: DL
authors.lastname: Evans
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D013373:Substance P / Q000097:blood*
chemical_list: D013373:Substance P