title: Prevention of nickel release with barrier coatings.
abstract: BACKGROUND
  Allergic contact dermatitis from nickel is very common in the United States. A barrier coating to be used on personal items such as snaps or watches would be of great use in preventing the consequences of nickel allergy.
  
  
  OBJECTIVE
  To evaluate various barrier coatings and their ability to yield a negative dimethylglyoxime (DMG) test result.
  
  
  METHODS
  Four different barrier coatings were assessed prior to soaking in saline, after soaking in saline for 2 days, and after soaking in saline for 7 days.
  
  
  RESULTS
  Depending on the number of coatings and the time soaked in saline, the different barriers showed different efficacies in yielding a negative DMG test result.
  
  
  CONCLUSIONS
  Nickel Guard and Beauty Secrets Hardener were most effective in yielding a negative DMG test result. Beauty Secrets Hardener was the more cost-effective choice.
authors.affiliation: Department of Dermatology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, PA, USA.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Sprigle
authors.forename: James G
authors.initials: JG
authors.lastname: Marks
authors.forename: Bryan E
authors.initials: BE
authors.lastname: Anderson
mesh_terms: D000269:Adhesives; D017449:Dermatitis, Allergic Contact / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007764:Lacquer; D009532:Nickel / Q000633:toxicity*; D010091:Oximes; D010328:Patch Tests; D020011:Protective Agents / Q000008:administration & dosage*; D014481:United States
chemical_list: D000269:Adhesives; D010091:Oximes; D020011:Protective Agents; C013501:dimethylglyoxime; D009532:Nickel