title: Characterization of a novel pyridinium bromide surface confined ionic liquid stationary phase for high-performance liquid chromatography under normal phase conditions via linear solvation energy relationships.
abstract: Utilizing linear solvation free energy relationship methodology, a novel pyridinium bromide surface confined ionic liquid (SCIL) stationary phase was characterized under normal phase high-performance liquid chromatographic conditions. A limited set of neutral aromatic probe solutes were utilized to rapidly assess the utility of the LSER model, using mobile phases of hexane modified with 2-propanol. The excellent correlation of the global fit across the mobile phase composition range used in this study for the experimental and calculated retention values (R(2)=0.994) indicates that the LSER model is an appropriate model of characterizing this polar bonded phase under normal phase conditions. For a limited subset of compounds, retention on the pyridinium bromide SCIL stationary phase is more highly correlated with that obtained on a cyano column than on a diol column under NP conditions.
authors.affiliation: Department of Chemistry, PO Box 210172, University of Cincinnati, Cincinnati, OH 45221-0172, USA.
authors.forename: D S
authors.initials: DS
authors.lastname: Van Meter
authors.forename: O D
authors.initials: OD
authors.lastname: Stuart
authors.forename: A B
authors.initials: AB
authors.lastname: Carle
authors.forename: A M
authors.initials: AM
authors.lastname: Stalcup
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D011726:Pyridinium Compounds / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D011726:Pyridinium Compounds