[Association between mitochondrial DNA mutations and cancer in human].
Mitochondria are essential organelles that generate cellular energy in cells. Mutations of mitochondrial DNA (mtDNA) have been identified in various types of cancer, suggesting a complex relationship between mtDNA and cancer. This review focuses on the possible correlation between the mtDNA mutation and cancer. Additionally, possible causes for mtDNA mutations and applications for detecting mtDNA mutations in cancer are discussed.
Zhang
Shu-Ping
SP
College of Life Science, Capital Normal University, Beijing 100037, China. zhangshuping333@163.com
Song
Shu-Juan
SJ
Li
Ya-Xuan
YX
D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*
D004272:DNA, Mitochondrial