title: Maternal anxiety predicts favourable treatment outcomes in anxiety-disordered adolescents.
abstract: OBJECTIVE
  To determine the differential impact of maternal and paternal internalizing psychopathology on cognitive-behavioural treatment (CBT) outcome of anxiety-disordered children and adolescents.
  
  
  METHODS
  Participants consisted of 127 children and 51 adolescents with a primary anxiety diagnosis. Children were randomly assigned to a standardized group CBT or individual CBT; adolescents received individual CBT. Parents received four training sessions. Participants were evaluated at pre- and post-treatment with a clinical interview and with self- and parent-reported questionnaires. Lifetime anxiety and mood disorders in parents were obtained with a clinical interview.
  
  
  RESULTS
  For children, no associations were found between maternal and paternal anxiety or mood disorders and treatment outcome. For adolescents, however, maternal lifetime anxiety disorders were positively associated with pre-post-treatment improvement in clinician severity ratings and with treatment success.
  
  
  CONCLUSIONS
  Lifetime maternal anxiety disorders were significantly associated with favourable treatment outcomes in adolescents. Paternal disorders were not associated with treatment response.
authors.affiliation: Department of Child and Adolescent Psychiatry, Erasmus Medical Centre Rotterdam/Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: J S
authors.initials: JS
authors.lastname: Legerstee
authors.forename: A C
authors.initials: AC
authors.lastname: Huizink
authors.forename: W
authors.initials: W
authors.lastname: van Gastel
authors.forename: J M
authors.initials: JM
authors.lastname: Liber
authors.forename: P D A
authors.initials: PD
authors.lastname: Treffers
authors.forename: F C
authors.initials: FC
authors.lastname: Verhulst
authors.forename: E M W J
authors.initials: EM
authors.lastname: Utens
mesh_terms: D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D016241:Child of Impaired Parents / Q000523:psychology* / Q000706:statistics & numerical data*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005220:Fathers / Q000523:psychology / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D009035:Mothers / Q000523:psychology* / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome