title: Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals.
authors.affiliation: Department of Chemistry and Institute of Basic Sciences, Chonnam National University, Gwangju 500-757, Korea.
authors.forename: Suk-Youl
authors.initials: SY
authors.lastname: Park
authors.forename: Woo-Ram
authors.initials: WR
authors.lastname: Lee
authors.forename: Suk-Chan
authors.initials: SC
authors.lastname: Lee
authors.forename: Myung-Hee
authors.initials: MH
authors.lastname: Kwon
authors.forename: Yong-Sung
authors.initials: YS
authors.lastname: Kim
authors.forename: Jeong-Sun
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000974:Antibodies, Antinuclear / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D001665:Binding Sites; D002104:Cadmium / Q000737:chemistry / Q000378:metabolism; D003035:Cobalt / Q000737:chemistry / Q000378:metabolism; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics; D006868:Hydrolysis; D007128:Immunoglobulin Fragments / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D019216:Metals, Heavy / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D017422:Sequence Analysis, DNA; D014169:Transformation, Bacterial; D014325:Tromethamine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D014867:Water / Q000737:chemistry
chemical_list: D000974:Antibodies, Antinuclear; D007128:Immunoglobulin Fragments; D019216:Metals, Heavy; D011994:Recombinant Proteins; C055966:immunoglobulin Fv; D002104:Cadmium; D014325:Tromethamine; D014867:Water; D003035:Cobalt; D004247:DNA; C026272:Bistris