Panton-Valentine leukocidin-producing methicillin-Sensitive Staphylococcus aureus as a cause for recurrent, contagious skin infections in young, healthy travelers returned from a tropical country: a new worldwide public health problem?
Skin infections associated with visits to tropical countries are well known. In most of the cases, the infection is caused by Staphylococcus aureus. After a sufficient antibiotic treatment, the skin infections resolve without any sequelae. But several patients suffer from recurrent skin infections. Panton-Valentine leukocidin (PVL) is a cytotoxin produced by S aureus, which is associated with severe necrotic skin lesions and with a high contagiosity.
Schleucher
Regina D
RD
Institute of Tropical Medicine, University of Tuebingen, Tuebingen, Germany. regina.schleucher@med.uni-tuebingen.de
Gaessler
Michael
M
Knobloch
Juergen
J
D000038:Abscess / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000096:biosynthesis / Q000302:isolation & purification*; D005098:Exotoxins / Q000096:biosynthesis / Q000302:isolation & purification*; D005260:Female; D005367:Fiji; D005858:Germany; D005869:Ghana; D006801:Humans; D007956:Leukocidins / Q000096:biosynthesis / Q000302:isolation & purification*; D008297:Male; D016106:Methicillin Resistance; D012008:Recurrence; D013207:Staphylococcal Skin Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification* / Q000378:metabolism; D016896:Treatment Outcome; D014329:Tropical Climate
D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin