Complementarity of standard cytogenetic assays.
Standard cytogenetic assays used in genotoxicology usually include chromosome aberrations analysis and micronucleus cytokinesis-block assay. Both tests originate on standard protocol for lymphocyte culture and can be used as complement or substitute to each other. Aim of this study was to evaluate complementarities between results of chromosome aberration analysis assay and results of micronucleus cytokinesis-block assay in representative sample of inhabitants from Bosnia and Herzegovina. The aim was achieved by calculating Pearson correlation coefficient and simple linear regression.
Ibrulj
Slavka
S
Faculty of Medicine, University of Sarajevo, Cekalusa 90, 71 000 Sarajevo, Bosnia and Herzegovina.
Haverić
Sanin
S
Haverić
Anja
A
D000328:Adult; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D020732:Cytogenetic Analysis / Q000379:methods*; D048749:Cytokinesis / Q000502:physiology; D005260:Female; D006801:Humans; D016014:Linear Models; D008214:Lymphocytes / Q000473:pathology / Q000502:physiology; D008297:Male; D048629:Micronuclei, Chromosome-Defective; D008875:Middle Aged; D015203:Reproducibility of Results