[Research progress on diacylgycerol acyltransferase 2 (DGAT2) gene].
Diacylgycerol acyltransferase2 (DGAT2) is an important enzyme in many organisms. DGAT2 catalyzes the final step of triacylglycerol (TAG) biosynthesis by converting diacylgycerol (DAG) and fatty acyl-coenzyme A (CoA) into TAG. This enzyme is encoded by both DGAT2 and DGAT1 genes. This paper reviews the discovery of the DGAT2 gene, its structure, chromosomal location and biological effect. The relationship between its genetic polymorphisms and animal performance traits is also discussed. The review ends with future prospects.
Yuan
Zheng-Rong
ZR
College of Animal Science & Technology, Hunan Agricultural University, Changsha 410128, China. zhengrong_yuan@yahoo.com.cn
Liu
Xiao-Chun
XC
Ma
Hai-Ming
HM
Ding
Zhao-Yang
ZY
D000818:Animals; D051048:Diacylglycerol O-Acyltransferase / Q000235:genetics* / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D011110:Polymorphism, Genetic / Q000235:genetics; D014280:Triglycerides / Q000378:metabolism
D014280:Triglycerides; D051048:Diacylglycerol O-Acyltransferase