title: Aging and cancer cell biology, 2008.
abstract: There is increasing support for the idea that aging and cancer are intimately connected by the activity of specific genes and the cellular responses to potentially oncogenic insults. This Hot Topics review discusses some recently published articles that shed light on both the commonalities--and intricacies--of the cancer-aging relationship. These articles reveal the expected complexities, but also surprising conservation, in mechanisms that link cancer and aging.
authors.affiliation: Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. jcampisi@lbl.gov
authors.forename: Judith
authors.initials: J
authors.lastname: Campisi
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000502:physiology; D016922:Cellular Senescence / Q000235:genetics / Q000502:physiology; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism
chemical_list: D016159:Tumor Suppressor Protein p53