title: [Efficacy and safety of Fufang Biejia Ruangan tablet in patients with chronic hepatitis B complicated with hepatic fibrosis].
abstract: OBJECTIVE
  To study the clinical therapeutic effects and safety of Fufang Biejia Ruangan tablet (FBRt) in patients with chronic hepatitis B complicated with hepatic fibrosis.
  
  
  METHODS
  Totally 420 patients were randomly divided into two groups, FBRt group (300 cases) were treated with Fufang Biejia Ruangan tablets and control group (120 cases) were treated with He Luo Shu Gan capsule, the patients in both groups were treated for 6 months.
  
  
  RESULTS
  The cure rate and total effective rate of FBRt group were significantly higher than those of control group (55.67 percent and 81.67 percent vs. 15.8 percent and 60.00 percent, P less than 0.01).
  
  
  CONCLUSIONS
  Fufang Biejia Ruangan tablet could alleviate clinical symptoms and hepatic fibrosis. Fufang Biejia Ruangan tablet is effective and safe in treatment of patients with chronic hepatitis B complicated with liver fibrosis.
authors.affiliation: The No. 302 Hospital of the Chinese People's Liberation Army, Beijing 100039, China.
authors.forename: Ju-mei
authors.initials: JM
authors.lastname: Chen
authors.forename: Yong-ping
authors.initials: YP
authors.lastname: Yang
authors.forename: De-yong
authors.initials: DY
authors.lastname: Chen
authors.forename: Jin
authors.initials: J
authors.lastname: Han
authors.forename: Xue-yuan
authors.initials: XY
authors.lastname: Jin
authors.forename: Ze-xiang
authors.initials: ZX
authors.lastname: Huang
authors.forename: Cheng-bin
authors.initials: CB
authors.lastname: Xu
authors.forename: Yan-ming
authors.initials: YM
authors.lastname: Shen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D019694:Hepatitis B, Chronic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology / Q000503:physiopathology; D008103:Liver Cirrhosis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D013607:Tablets
chemical_list: D013607:Tablets; D000410:Alanine Transaminase