title: HIV-associated nemaline rod myopathy: role of intravenous immunoglobulin therapy in two persons with HIV/AIDS.
abstract: Nemaline rod myopathy is a rare disease associated with muscle weakness and the presence of rod-shaped structures in the muscle fibers. Various acquired conditions have been associated with slow progressing presentations during adulthood. Several cases have been diagnosed in adults with HIV infection. The use of intravenous immunoglobulin (IVIG) has not been previously described for the treatment of these patients. We report the cases of 2 patients with HIV-related nemaline rod myopathy who successfully responded to IVIG therapy.
authors.affiliation: Grand Rapids Medical Education and Research Center, Grand Rapids, Michigan, USA.
authors.forename: Jorgelina T
authors.initials: JT
authors.lastname: de Sanctis
authors.forename: Gustavo
authors.initials: G
authors.lastname: Cumbo-Nacheli
authors.forename: David
authors.initials: D
authors.lastname: Dobbie
authors.forename: David
authors.initials: D
authors.lastname: Baumgartner
mesh_terms: D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D018485:Muscle Fibers, Skeletal / Q000473:pathology / Q000648:ultrastructure; D018482:Muscle, Skeletal / Q000473:pathology / Q000648:ultrastructure; D017696:Myopathies, Nemaline / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors