title: Early hyperglycemia after allogenic kidney transplantation: does it induce infections.
abstract: BACKGROUND
  Although impact of diabetes mellitus after solid organ transplantation is a broadly investigated issue, a potential impact of early hyperglycemia after renal transplantation has not received enough consideration. In this study, we aimed to evaluate the potential impact of early hyperglycemia on the hazards of infections development leading to re-hospitalization.
  
  
  METHODS
  We evaluated 1931 non diabetic renal allograft recipients, undergone renal transplantation at the Baqiyatallah Hospital, Tehran from 1984 to 2006. Level of hyperglycemia was defined at 126 mg/dL. Patients who had at least two glucose concentration results over the mentioned level in two different days during their early post transplantation period were determined as hyperglycemic.
  
  
  RESULTS
  Overall, 7.6% of patients were determined as having early post transplant hyperglycemia. Multivariable hazard analysis using Cox regression model showed that early post transplantation hyperglycemia has an independent impact on rehospitalization of non-diabetic kidney allograft recipients for developing infectious diseases.
  
  
  CONCLUSIONS
  Regarding findings of our study and previous studies we conclude that renal transplant recipients who develop hyperglycemia during their early post transplantation period should receive higher amount of attention over their follow up periods.
authors.affiliation: Nephrology & Urology Research Center (NURC), Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Mahbobeh Sadat
authors.initials: MS
authors.lastname: Hosseini
authors.forename: Eghlim
authors.initials: E
authors.lastname: Nemati
authors.forename: Vahid
authors.initials: V
authors.lastname: Pourfarziani
authors.forename: Saeed
authors.initials: S
authors.lastname: Taheri
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Nourbala
authors.forename: Behzad
authors.initials: B
authors.lastname: Einollahi
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology*; D007239:Infections / Q000209:etiology*; D007492:Iran; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D013997:Time Factors