title: [Estimation of the specific sensitization in a child and other immunological parameters in tuberculosis of intrathoracic lymph nodes during therapy].
abstract: The data of a comprehensive study of 86 children aged 6 to 14 years, who were examined and treated at the Research Institute of Phthisiology for various manifestations of tuberculous infection: 25.6% with infected Mycobacterium tuberculosis with varying specific sensitization; 34.9% with minor forms of intrathoracic lymph node tuberculosis (ILNT), and 39.5% with disseminated processes into the intrathoracic lymph nodes. RM V, VI, VII, and VIII dilutions are of the greatest informative value in the determination of the activity of tuberculous infection. Most children with ILNT showed a significant cellular response to PPD in the LBT test, The LCT test revealed that neutrophilic granulocytes were functionally inadequate in all the children. The currently available immunological tests used in combination with the existing methods adequately evaluate the activity of tuberculous infection in children.
authors.forename: S N
authors.initials: SN
authors.lastname: efremova
authors.forename: I F
authors.initials: IF
authors.lastname: Dovgaliuk
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Sakharova
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000008:administration & dosage; D002648:Child; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology* / Q000473:pathology*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000276:immunology / Q000473:pathology
chemical_list: D000995:Antitubercular Agents; D001500:BCG Vaccine