title: Vitamin A and sleep regulation.
abstract: Vitamin A is the parent compound of retinoids, which regulate gene transcription by binding to nuclear retinoid receptors. Recently, it has been suggested that retinoid signaling pathways are important for adult neural function in health and disease. In this mini review we will summarize the molecular pathway of retinoid and experimental data on this pathway relating to sleep regulation, which suggests that retinoid signaling mechanism may be involved in the homeostatic component of sleep electroencephalogram.
authors.affiliation: Department of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Sei
mesh_terms: D000818:Animals; D004569:Electroencephalography; D006706:Homeostasis; D006801:Humans; D051379:Mice; D018168:Receptors, Retinoic Acid / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D012890:Sleep / Q000502:physiology*; D014801:Vitamin A / Q000502:physiology*; D014802:Vitamin A Deficiency / Q000503:physiopathology
chemical_list: D018168:Receptors, Retinoic Acid; D014801:Vitamin A