[Malignancy of familial adenomatous polyposis. Diagnosis and treatment].
Familial adenomatous polyposis with features of malignancy find in a 23 years old patient, whose diagnosis has been established on endoscopical basis. Total proctocolectomy is performed with terminal ileostomy. Histopathologically, the diagnosis is revealed, with establishing of multiple areas of malignancy in rectum and sigmoid colon. In the postoperative period, the patient is treated by pelvic radiotherapy and polychemotherapy. After one year, the clinical outcome is good, with weight gain 13 Kg and finishing high school. After two years, peritoneal carcinomatosis and one lung metastasis.
Palade
R
R
Clinica Chirurgie I, Spitalul Universitar de Urgenţă Bucureşti, UMF Carol Davila, Bucureşti, România. radupalade@yahoo.com
Tomescu
M
M
Suliman
E
E
Popa
D
D
D000230:Adenocarcinoma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D011125:Adenomatous Polyposis Coli / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D003082:Colectomy; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007081:Ileostomy; D008297:Male; D016737:Proctocolectomy, Restorative; D011878:Radiotherapy; D016896:Treatment Outcome