title: Audit of internal quality control practice and processes in the south-east of England and suggested regional standards.
abstract: BACKGROUND
  Internal quality control (IQC) has a long and well-established role in clinical biochemistry laboratories. However, despite the duration of use, and the publication of several articles detailing best practice, the implementation and use of IQC vary significantly between institutions. Consequently, the North Thames Audit and Quality Assurance Group undertook a region-wide audit of current IQC practice in 2006.
  
  
  METHODS
  On aspects of IQC testing, interpretation and laboratory processes, 54 laboratories in the region were audited.
  
  
  RESULTS
  Audit data showed significant variability in all aspects of practice, including IQC frequency, use of appropriate material, statistical processing and grades of staff involved.
  
  
  CONCLUSIONS
  Some of the variation in practice may affect the effectiveness of laboratory IQC, and thus the adequacy of a laboratory to monitor system performance. Consequently, a set of proposed regional standards have been developed and disseminated, prior to re-audit at a future date.
authors.affiliation: Department of Clinical Biochemistry, Luton & Dunstable Hospital NHS Foundation Trust, Lewsey Road, Luton LU4 0DZ, UK. David.Housley@nhs.net
authors.forename: David
authors.initials: D
authors.lastname: Housley
authors.forename: Edward
authors.initials: E
authors.lastname: Kearney
authors.forename: Emma
authors.initials: E
authors.lastname: English
authors.forename: Natalie
authors.initials: N
authors.lastname: Smith
authors.forename: Teresa
authors.initials: T
authors.lastname: Teal
authors.forename: Janina
authors.initials: J
authors.lastname: Mazurkiewicz
authors.forename: Danielle B
authors.initials: DB
authors.lastname: Freedman
mesh_terms: D054869:Clinical Audit; D019411:Clinical Laboratory Techniques / Q000592:standards*; D004739:England; D006801:Humans; D011785:Quality Assurance, Health Care; D011786:Quality Control; D012016:Reference Values