title: [Diabetes insipidus in a pacient with multiple sclerosis].
abstract: Multiple Sclerosis (ME) is a chronic progressive disease characterized by relapses of demyelination that can occur anywhere in the brain stem, spinal cord and optic nerve. Since central diabetes insipidus (DI) is mainly caused by central nervous system damage (such as trauma, surgery, tumor, infection, sarcoidosis), ME is included among its possible etiologies. However, this association is not commonly described. The clinical suspicion must be made in the presence of polyuria and polydipsia or refractory hypernatremia (in patients without free access to water) during the evolution of ME. We will describe a clinical report in which this association occurred and, after the beginning of desmopressin therapy, the clinical findings were reverted.
authors.affiliation: Disciplina de Medicina de Urgência, Universidade Federal de São Paulo, Brazil. fegweiler@yahoo.com.br
authors.forename: Fernanda G
authors.initials: FG
authors.lastname: Weiler
authors.forename: Kátia
authors.initials: K
authors.lastname: Blumberg
authors.forename: Claudia S
authors.initials: CS
authors.lastname: Liboni
authors.forename: Eduardo A C
authors.initials: EA
authors.lastname: Roque
authors.forename: Aécio F T de
authors.initials: AF
authors.lastname: Góis
mesh_terms: D000328:Adult; D050034:Antidiuretic Agents / Q000627:therapeutic use; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D020790:Diabetes Insipidus, Neurogenic / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009103:Multiple Sclerosis / Q000150:complications*; D011141:Polyuria / Q000209:etiology
chemical_list: D050034:Antidiuretic Agents; D003894:Deamino Arginine Vasopressin