title: Osseointegrated trans-femoral amputation prostheses: prospective results of general and condition-specific quality of life in 18 patients at 2-year follow-up.
abstract: This is the first report on prospective outcome for individuals treated with bone-anchored trans-femoral amputation prostheses (OI-prostheses) using the method of osseointegration. The aim was to analyze general and condition-specific health related quality of life (HRQL) at 2-year follow-up as compared to the preoperative situation. The study population consists of the first 18 consecutively treated patients (8 male/10 female, mean age 45 years) in a clinical investigation with amputations mainly caused by trauma and tumour. At inclusion the mean time since the amputation was 15 years (10 months - 33 years). Two self-report questionnaires were answered preoperatively and at follow-up: the SF-36 Health Survey (SF-36) and the Questionnaire for persons with a Transfemoral Amputation (Q-TFA). At follow-up 17/18 patients used the OI-prosthesis; one did not due to pain and loosening of the implant. Four of the scales of the SF-36 (Physical Functioning, Role Functioning Physical, Bodily Pain and Physical Component Score) and all four scores of Q-TFA (Prosthetic Use, Prosthetic Mobility, Problems and Global Health) were statistically significantly improved at follow-up showing superior general physical HRQL, increased prosthetic use, better prosthetic mobility, fewer problems and a better global amputation situation. Thus, osseointegrated prostheses represent a promising development in the rehabilitation of individuals with transfemoral amputation and increase their quality of life.
authors.affiliation: Department of Prosthetics and Orthotics, Sahlgrenska University Hospital, Göteborg University, Göteborg, Sweden. kerstin.hagberg@vgregion.se
authors.forename: Kerstin
authors.initials: K
authors.lastname: Hagberg
authors.forename: Rickard
authors.initials: R
authors.lastname: Brånemark
authors.forename: Björn
authors.initials: B
authors.lastname: Gunterberg
authors.forename: Björn
authors.initials: B
authors.lastname: Rydevik
mesh_terms: D000328:Adult; D000674:Amputees / Q000523:psychology*; D001186:Artificial Limbs; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D009984:Orthopedic Fixation Devices; D016348:Osseointegration; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires