title: [Bilateral papilledema: prospective study of fifty patients].
abstract: In this prospective study, we report fifty consecutive cases of bilateral papilledema without neurosurgical or obvious ophthalmologic etiology, referred to our institution between January 2005 and March 2007. Lumbar puncture with opening CSF pressure measurement distinguished two groups of patients: Group 1 (n=39) with and Group 2 (n=11) without intracranial hypertension. In Group 1, 9/39 patients presented secondary intracranial hypertension mainly due to cerebral venous thrombosis. In 30 patients, after complete investigations, a diagnosis of idiopathic intracranial hypertension was made: as commonly reported, patients were predominantly overweight (96.7% with body mass index>25kg/m2) young (mean age=27.6 years) and women (96.7%). Eleven patients with intracranial hypertension had no headaches. In Group 2, the most common diagnosis was bilateral non-arteritic anterior ischemic optic neuropathy, but rare causes have been identified.
authors.affiliation: Service de neurologie, fondation ophtalmologique Adolphe-de-Rothschild, 25 à 29, rue Manin, 75940 Paris cedex 19, France. rom.deschamps@wanadoo.fr
authors.forename: R
authors.initials: R
authors.lastname: Deschamps
authors.forename: C
authors.initials: C
authors.lastname: Dehais
authors.forename: F
authors.initials: F
authors.lastname: Heran
authors.forename: M
authors.initials: M
authors.lastname: Obadia
authors.forename: L
authors.initials: L
authors.lastname: Laloum
authors.forename: C
authors.initials: C
authors.lastname: Fechner
authors.forename: C
authors.initials: C
authors.lastname: Vignal-Clermont
authors.forename: O
authors.initials: O
authors.lastname: Gout
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications; D020767:Intracranial Thrombosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D010211:Papilledema / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D011446:Prospective Studies; D012727:Sex Characteristics