Identification of a novel HLA-B*54 allele, B*5411, by sequence-based typing in a Chinese individual.
We report here a novel human leukocyte antigen (HLA)-B*5411 allele identified by sequence-based typing in a Chinese individual. The novel B*5411 is identical to B*5404, with the exception of four base substitutions at position 120 (A>C), 134 (G>C), 143 (C>G), and 156 (A>T) of exon 3 resulting in codon no. 131, changed from AGC (Ser) to CGC (Arg), and codon no. 143, changed from ACC (Thr) to TCC (Ser).
Yan
L-N
LN
Tissue Typing Laboratory, Tianjin Blood Center, Tianjin, China.
Li
S-Y
SY
Dong
Z
Z
Dong
L
L
Xie
J-H
JH
Yuan
Y-H
YH
An
S-P
SP
D000483:Alleles; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D015235:HLA-B Antigens