title: [Neurological defects and developmental disorders following neonatal extracorporeal membrane oxygenation: results of a follow-up study after 5 years].
abstract: OBJECTIVE
  Descriptive study of the development of children 5 years after neonatal extracorporeal membrane oxygenation (ECMO).
  
  
  METHODS
  Descriptive.
  
  
  METHODS
  98 treated children were subjected to a paediatric, neurological, psychological, physiotherapeutic and logopaedic examination. The children came from 2 Dutch ECMO-centres (the Erasmus MC-Sophia Children's Hospital in Rotterdam and the University Medical Centre St Radboud in Nijmegen, The Netherlands).
  
  
  RESULTS
  Neurological disorders were found in 17 of the 98 investigated children, and in 6 cases these were serious. Among the remaining 92 children, 24 had motor disorders and 11 had delayed cognitive development. The average IQ (100.5) was within the normal range.
  
  
  CONCLUSIONS
  A significant proportion ofthe children that had been treated with ECMO had long-term morbidity in the form of neurological defects and developmental disorders.
authors.affiliation: Erasmus MC-Sophia Kinderziekenhuis, Rotterdam.
authors.forename: M N
authors.initials: MN
authors.lastname: Hanekamp
authors.forename: P
authors.initials: P
authors.lastname: Mazer
authors.forename: M H M
authors.initials: MH
authors.lastname: van der Cammen-van Zijp
authors.forename: B J M
authors.initials: BJ
authors.lastname: van Kessel-Feddema
authors.forename: M W G
authors.initials: MW
authors.lastname: Nijhuis-van der Sanden
authors.forename: S
authors.initials: S
authors.lastname: Knuijt
authors.forename: J L A
authors.initials: JL
authors.lastname: Zegers-Verstraeten
authors.forename: S J
authors.initials: SJ
authors.lastname: Gischler
authors.forename: D
authors.initials: D
authors.lastname: Tibboel
authors.forename: L A A
authors.initials: LA
authors.lastname: Kollée
mesh_terms: D002675:Child, Preschool; D002658:Developmental Disabilities / Q000453:epidemiology*; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009422:Nervous System Diseases / Q000453:epidemiology*; D009426:Netherlands / Q000453:epidemiology; D015995:Prevalence; D012720:Severity of Illness Index