title: Relapsing Guillain Barré Syndrome and nephrotic syndrome secondary to focal segmental glomerulosclerosis.
abstract: A 49-year-old man developed simultaneously a Guillain Barré Syndrome (GBS) and a nephrotic syndrome (NS). The patient relapsed twice, despite treatment with intravenous immunoglobulins (IVIg) after a full or partial recovery, and became resistant to IVIg. Renal biopsy revealed focal segmental glomerulosclerosis (FSGS). He responded to plasmapheresis and corticosteroids with simultaneous recovery of his GBS and NS, suggesting a common pathogenesis of the two conditions.
authors.affiliation: Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA. souayani@umdnj.edu
authors.forename: Nizar
authors.initials: N
authors.lastname: Souayah
authors.forename: Didier
authors.initials: D
authors.lastname: Cros
authors.forename: T D
authors.initials: TD
authors.lastname: Stein
authors.forename: Peter Siao Tick
authors.initials: PS
authors.lastname: Chong
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000628:therapy; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000628:therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications* / Q000628:therapy; D010956:Plasmapheresis / Q000379:methods
chemical_list: D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous