title: Renal thrombotic microangiopathy and cerebral venous thrombosis in a young man.
abstract: We report a patient of primary catastrophic antiphospholipid syndrome who presented with rapidly progressive renal failure and seizures. He was detected to have thrombotic microangiopathy on kidney biopsy and deep cerebral venous thrombosis. The patient was successfully managed with anticoagulants, steroids, plasmapheresis and cyclophosphamide.
authors.affiliation: Department of Nephrology, Army Hospital (Research and Referral), Delhi Cantt, New Delhi 110010, India.
authors.forename: P P
authors.initials: PP
authors.lastname: Varma
authors.forename: H
authors.initials: H
authors.lastname: Khurana
authors.forename: A K
authors.initials: AK
authors.lastname: Hooda
authors.forename: V
authors.initials: V
authors.lastname: Marwaha
authors.forename: S
authors.initials: S
authors.lastname: Badwal
mesh_terms: D058186:Acute Kidney Injury / Q000503:physiopathology*; D000328:Adult; D000927:Anticonvulsants; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000503:physiopathology; D003520:Cyclophosphamide; D018450:Disease Progression; D006801:Humans; D008297:Male; D010956:Plasmapheresis; D013256:Steroids; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants; D013256:Steroids; D003520:Cyclophosphamide