[Socio-demographic, lifestyle, gynecological, and obstetric predictors of serum or plasma concentrations of homocysteine, folic acid, and vitamins B12 and B6 among low-income women in São Paulo, Brazil].
This study examined the socio-demographic, lifestyle, gynecological, and obstetric factors associated with serum or plasma concentrations of homocysteine, folic acid, and vitamins B12 and B6 among low-income women in São Paulo, Brazil. Serum concentrations of folic acid and vitamin B12 were measured by fluoroimmunoassay, while plasma vitamin B6 and homocysteine levels were measured by reversed-phase high performance liquid chromatography. Independent variables were initially selected by Pearson correlation or Kruskal-Wallis test (p < 0.20). Based on cut-off values, altered concentrations of homocysteine, folic acid, and vitamins B12 and B6 were found in 20%, 6%, 11%, and 67% of participants, respectively. Age was positively correlated with vitamin B6 and homocysteine plasma concentrations (p < 0.001). Body mass index was positively correlated with vitamin B6 plasma concentration (p < 0.001). Multiple linear regression models accounted for 10.2%, 5.8%, 14.4%, and 9.4% of folic acid, vitamins B12 and B6, and homocysteine plasma or serum concentrations, respectively. In this study, socio-demographic, lifestyle, gynecological, and obstetric variables showed important predictive value for serum or plasma levels of the biochemical indicators assessed.
Almeida
Lana Carneiro
LC
Faculdade de Saúde Pública, Universidade de São Paulo, Sço Paulo, Brasil.
Tomita
Luciana Yuki
LY
D'Almeida
Vânia
V
Cardoso
Marly Augusto
MA
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D001938:Brazil; D002851:Chromatography, High Pressure Liquid; D003430:Cross-Sectional Studies; D005260:Female; D015200:Fluoroimmunoassay; D005492:Folic Acid / Q000097:blood*; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D009752:Nutritional Status; D011203:Poverty; D017584:Reproductive History; D012959:Socioeconomic Factors; D014803:Vitamin B Complex / Q000097:blood*; D014932:Women's Health Services; D055815:Young Adult
D006710:Homocysteine; D014803:Vitamin B Complex; D005492:Folic Acid