title: Vicinal functionalization of propiolate esters via a tandem catalytic carbocupration-Mukaiyama aldol reaction sequence.
abstract: The vicinal functionalization of propiolate esters via a tandem catalytic carbocupration-Mukaiyama aldol reaction sequence has been investigated. It has been shown that catalyst loadings as low as 8 mol % readily allow for good yields and excellent diastereoselectivities (>20:1) for a series of Grignard reagents and aldehydes.
authors.affiliation: Department of Chemistry, The University of Alabama, Tuscaloosa, AL 35487-0336, USA.
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Mueller
authors.forename: Michael P
authors.initials: MP
authors.lastname: Jennings