[Alkaloid constituents from silkworm dropping of Bombyx mori].
OBJECTIVE
To extract and isolate chemical constituents from the total alkaloids of silkworm dropping (Can Sha) of Bombyx mori L.


METHODS
Chemical constituents were isolated by column chromatography with macroporous adsorbent resin, ion-exchange resin and sephadex LH 20. The structures of the isolated compounds were determined by spectral means.


RESULTS
Three compounds were isolated and identified as 1-deoxynojirimycin (1) , fagomine (2) , and 3-epifagomine (3) on the basis of their 1H-NMR, 13C-NMR spectra and ESIMS data.


CONCLUSIONS
Compounds 1-3 are isolated and identified from Can Sha for the first time.
Zhou
Guang-xiong
GX
Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Ruan
Jie-wu
JW
Huang
Mei-yan
MY
Ye
Wen-cai
WC
He
Ye-wei
YW
D017485:1-Deoxynojirimycin / Q000737:chemistry / Q000302:isolation & purification*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D012831:Bombyx / Q000737:chemistry*; D002852:Chromatography, Ion Exchange / Q000295:instrumentation / Q000379:methods; D050112:Imino Pyranoses / Q000737:chemistry / Q000302:isolation & purification*; D007475:Ion Exchange Resins; D007814:Larva / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012117:Resins, Synthetic
D000470:Alkaloids; D050112:Imino Pyranoses; D007475:Ion Exchange Resins; D012117:Resins, Synthetic; D017485:1-Deoxynojirimycin; C105643:fagomine