title: Polymorph control: past, present and future.
abstract: The appearance and disappearance of polymorphs is no longer a mysterious and inexplicable process. Although methods for polymorph control are still imperfect, there is a large armoury of methods that can be used to tackle this important and challenging problem. We survey the methods and their successes over the last few years.
authors.affiliation: Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom. Antonio.Llinas@ch.cam.ac.uk
authors.forename: Antonio
authors.initials: A
authors.lastname: Llinàs
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Goodman
mesh_terms: D003460:Crystallization / Q000379:methods* / Q000639:trends*; D006801:Humans; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods / Q000639:trends; D013816:Thermodynamics; D014961:X-Ray Diffraction
chemical_list: D004364:Pharmaceutical Preparations; D012997:Solvents