title: The morbidity of transperineal template-guided prostate mapping biopsy.
abstract: OBJECTIVE
  To evaluate the effect of transperineal template-guided prostate mapping biopsy (TTMB) on urinary, bowel and erectile function.
  
  
  METHODS
  In all, 129 men had TTMB; a median of 56 biopsy cores were obtained per patient. Tamsulosin (0.8 mg daily) was initiated 2 days before TTMB and continued for 2 weeks. The International Prostate Symptom Score (IPSS), Rectal Function Assessment Score (R-FAS), International Index of Erectile Function (IIEF)-6 and the postvoid residual volume (PVR) were assessed at baseline and after 30 days, except for the IPSS, which was also assessed at 7 days. Several variables were evaluated as predictors of TTMB-induced morbidity.
  
  
  RESULTS
  The mean patient age was 64.7 years with a mean prostate volume of 74.3 mL; 60 men (46.5%) were diagnosed with prostate cancer. After TTMB, 39.4%, 7.1% and 1.6% of patients remained catheter-dependent at 0, 3 and 6 days. The median catheter-dependency was 0, 1, 2 and 3 days for prostate volumes of <60, 60-90, 90-120 and >120 mL, respectively. No patient remained catheter- dependent for >12 days or required a transurethral resection secondary to TTMB. The mean IPSS before TTMB was 10.4, and was 4.6 and 3.8 at 7 and 30 days. At baseline and 30 days the mean PVR was 35 and 40 mL, and the median R-FAS and IIEF scores for patients potent before TTMB were 2.0 and 2.2, and 27.0 and 26.0, respectively.
  
  
  CONCLUSIONS
  TTMB is a promising procedure for diagnosing prostate cancer. TTMB-related morbidity differs from that of standard TRUS biopsy primarily in the incidence of temporary urinary retention, and is comparable in terms of urinary, bowel and erectile function.
authors.affiliation: Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV 26003-6300, USA. gmerrick@urologicresearchinstitute.org
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Merrick
authors.forename: Walter
authors.initials: W
authors.lastname: Taubenslag
authors.forename: Hugo
authors.initials: H
authors.lastname: Andreini
authors.forename: Sarah
authors.initials: S
authors.lastname: Brammer
authors.forename: Wayne M
authors.initials: WM
authors.lastname: Butler
authors.forename: Edward
authors.initials: E
authors.lastname: Adamovich
authors.forename: Zachary
authors.initials: Z
authors.lastname: Allen
authors.forename: Richard
authors.initials: R
authors.lastname: Anderson
authors.forename: Kent E
authors.initials: KE
authors.lastname: Wallner
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D007172:Erectile Dysfunction / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D014555:Urination Disorders / Q000517:prevention & control*