title: [Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter].
abstract: Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.
authors.affiliation: Central Clinical Laboratories, Mie University Hospital, Tsu.
authors.forename: Akane
authors.initials: A
authors.lastname: Sakaguchi
authors.forename: Hideo
authors.initials: H
authors.lastname: Wada
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Abe
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Tomatsu
authors.forename: Junji
authors.initials: J
authors.lastname: Nishioka
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Morishita
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Okuni
authors.forename: Masanobu
authors.initials: M
authors.lastname: Usui
authors.forename: Shuji
authors.initials: S
authors.lastname: Isaji
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nobori
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008107:Liver Diseases / Q000097:blood / Q000601:surgery; D016031:Liver Transplantation / Q000502:physiology*; D010976:Platelet Count; D011184:Postoperative Period; D013926:Thrombopoietin / Q000096:biosynthesis / Q000097:blood
chemical_list: D013926:Thrombopoietin