Spectroscopic study of hexahydroquinoline derivatives--a potential group of calcium antagonists.
Spectral properties of 2, 6, 6-trimethyl-3-carbmethoxy-4-phenyl-5-oxo -1,4,5,6,7,8-hexahydroquinoline derivatives (HHQ) with different substituents in the phenyl ring (-Cl, -NO2, -CF3, -CH3, -OCH3) have been studied. Their emission and absorption spectra have been analyzed and quantum yields of emission were determined. The quantum yield of emission was found to depend on the kind, number, and position of substituents in the phenyl ring: it was the highest for the chlorine derivatives of HHQ, and the lowest for the compounds containing -NO2 group.
Mielcarek
Jadwiga
J
Department of Inorganic and Analytical Chemistry, K. Marcinkowski University of Medical Sciences, 60-780 Poznań, Poland. jmielcar@am.poznan.pl
Simşek
Rahime
R
Safak
Cihat
C
Stefaniak
Hanna
H
D002121:Calcium Channel Blockers / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D002121:Calcium Channel Blockers; D011804:Quinolines