title: Prevention of contrast-induced nephropathy with sodium bicarbonate: an evidence-based protocol.
abstract: Contrast-induced nephropathy has continued to plague interventional cardiology as an all-too-frequent complication of diagnostic and therapeutic procedures. We present an evidence-based protocol for prevention of this complication that uses infusion of NaHCO3 to effect urinary alkalinization and possibly decrease free-radical renal injury resulting from contrast exposure.
authors.affiliation: Division of Nephrology, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Merten
authors.forename: W Patrick
authors.initials: WP
authors.lastname: Burgess
authors.forename: Robert A
authors.initials: RA
authors.lastname: Rittase
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Kennedy