title: Statistical analysis of twin populations using dissimilarity measurements in hippocampus shape space.
abstract: By analyzing interpoint comparisons, we obtain significant results describing the relationship in "hippocampus shape space" of clinically depressed, high-risk, and control populations. In particular, our analysis demonstrates that the high-risk population is closer in shape space to the control population than to the clinically depressed population.
authors.affiliation: Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USA. youngser@jhu.edu
authors.forename: Youngser
authors.initials: Y
authors.lastname: Park
authors.forename: Carey E
authors.initials: CE
authors.lastname: Priebe
authors.forename: Michael I
authors.initials: MI
authors.lastname: Miller
authors.forename: Nikhil R
authors.initials: NR
authors.lastname: Mohan
authors.forename: Kelly N
authors.initials: KN
authors.lastname: Botteron
mesh_terms: D000328:Adult; D003627:Data Interpretation, Statistical; D003865:Major Depressive Disorder / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004200:Diseases in Twins / Q000175:diagnosis*; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity