title: Magnetic resonance imaging (MRI) findings in white matter disease of brain.
abstract: Demyelinating and dysmyelinating white matter diseases are important components of neurological problems. Recently, Magnetic Resonance Imaging (MRI) has played a key role in diagnoses of white matter diseases. Therefore, the purpose of the current study is to evaluate the usefulness of MRI in determining the type and frequency of white matter disease. We studied 35 patients who visited the Radiology Department of the Aga Khan University Hospital (AKUH) for MRI with suspected demyelinating/dysmyelinating disorder from January 2003 to December 2005. Multiple Sclerosis (MS) (17; 48%) and leukodystrophies (10; 29%) were the most common diseases. The MRI helped identify the sites and types of the lesion precisely and thereby helped made clearer. distinction between various types of white matter diseases. The current study demonstrated the effective use of the imaging and clinical presentation for arriving at the correct diagnosis.
authors.affiliation: Department of Radiology, Aga Khan University Hospital, Karachi.
authors.forename: Humera
authors.initials: H
authors.lastname: Ahsan
authors.forename: Muhammad Zafar
authors.initials: MZ
authors.lastname: Rafique
authors.forename: Fozia
authors.initials: F
authors.lastname: Ajmal
authors.forename: Mohsin
authors.initials: M
authors.lastname: Wahid
authors.forename: Muhammad
authors.initials: M
authors.lastname: Azeemuddin
authors.forename: Farah
authors.initials: F
authors.lastname: Iqbal
mesh_terms: D000328:Adult; D001284:Atrophy; D001927:Brain Diseases / Q000175:diagnosis* / Q000503:physiopathology; D003711:Demyelinating Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010865:Pilot Projects