title: Demographic and illness-related variables associated with HIV-related fatigue.
abstract: Fatigue is one of the most debilitating symptoms suffered by those with HIV infection, yet little is known about its correlates. The primary aims of this study were to describe the degree to which fatigue affects daily functioning and the demographic and illness-related predictors of fatigue. The sample (n = 128) was composed of primarily poor, unemployed people of color. Fatigue most often interfered with the ability to think quickly, perform household chores, exercise, work, engage in recreational activities, walk, plan activities, and think clearly. The consequences of fatigue were highest for lowered motivation, difficulty concentrating, increased drowsiness, losing patience, and interference with work, family, and social life. Multiple linear regression analyses showed statistically significant associations of employment status, monthly income, current antidepressant use, and number of years living with HIV infection as predictors of fatigue. These must be better understood to develop interventions to successfully ameliorate HIV-related fatigue.
authors.affiliation: Duke University School of Nursing, Durham, North Carolina, USA.
authors.forename: James L
authors.initials: JL
authors.lastname: Harmon
authors.forename: Julie
authors.initials: J
authors.lastname: Barroso
authors.forename: Brian Wells
authors.initials: BW
authors.lastname: Pence
authors.forename: Jane
authors.initials: J
authors.lastname: Leserman
authors.forename: Naima
authors.initials: N
authors.lastname: Salahuddin
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D001294:Attitude to Health; D017281:Cost of Illness; D004651:Employment / Q000523:psychology; D005221:Fatigue / Q000503:physiopathology / Q000523:psychology* / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016018:Least-Squares Analysis; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015404:Nursing Methodology Research; D011788:Quality of Life / Q000523:psychology; D012720:Severity of Illness Index; D012919:Social Behavior; D015144:Southeastern United States