title: Bio-inspired polyene cyclization: synthesis of tetracyclic terpenoids promoted by steroidal acetal-SnCl4.
abstract: This communication describes a highly efficient intermolecular polyene cyclization method using steroidal acetals as the initiators to synthesize tetracyclic terpenoids; both good yields and good asymmetric induction were obtained.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 1 Nanyang Walk, Block 5 level 3, Singapore639798.
authors.forename: Yu-Jun
authors.initials: YJ
authors.lastname: Zhao
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D000080:Acetals / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013256:Steroids / Q000737:chemistry*; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry; D017971:Tin Compounds / Q000737:chemistry*
chemical_list: D000080:Acetals; D013256:Steroids; D013729:Terpenes; D017971:Tin Compounds; C041694:stannic chloride