title: Caffey disease with raised immunoglobulin levels and thrombocytosis.
abstract: Infantile cortical hyperostosis (Caffey disease) is characterized by radiological evidence of cortical hyperostosis, soft tissue swellings, fever and irritability. We report a case of Caffey disease highlighting its presentation with thrombocytosis and high serum immunoglobulin level to alert physicians to use steroids cautiously in view of the known thrombocythemic effect of the drug. Raised Immunoglobulin also suggests that this syndrome could be infectious in origin.
authors.affiliation: Child Health Unit 1, Christian Medical College, Vellore, India.
authors.forename: T Sathish
authors.initials: TS
authors.lastname: Kumar
authors.forename: Julius Xavier
authors.initials: JX
authors.lastname: Scott
authors.forename: Leni Grace
authors.initials: LG
authors.lastname: Mathew
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006958:Hyperostosis, Cortical, Congenital / Q000175:diagnosis / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D007223:Infant; D008334:Mandible / Q000000981:diagnostic imaging; D011859:Radiography; D013922:Thrombocytosis / Q000175:diagnosis / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M