Serum cholesterol-decreasing effect of heat-moisture-treated high-amylose cornstarch in cholesterol-loaded rats.
Rats were fed on a diet containing cholesterol (Chol) at a level corresponding to the standard Chol intake in humans, and the influence of heat-moisture-treated high-amylose cornstarch (HHA) on their serum Chol level was investigated. HHA decreased the serum level of Chol in rats fed on the diet containing 0.1% Chol, which corresponds to a Chol intake in humans of 800 mg/d, although the liver levels of Chol increased in these rats. HHA did not influence the fecal excretion of Chol/bile acids. It is possible that the decrease in serum Chol level in the rats fed on the high-Chol diet can be attributed to the promotion of Chol uptake in the liver.
Udagawa
Haruhide
H
Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Tokyo 156-8502, Japan. haruhideudagawa@ybb.ne.jp
Kitaoka
Chika
C
Sakamoto
Tatsuaki
T
Kobayashi-Hattori
Kazuo
K
Oishi
Yuichi
Y
Arai
Soichi
S
Takita
Toshichika
T
D000688:Amylose / Q000008:administration & dosage* / Q000494:pharmacology; D000818:Animals; D002784:Cholesterol / Q000032:analysis / Q000097:blood*; D005243:Feces / Q000737:chemistry; D006358:Hot Temperature; D006813:Humidity; D008099:Liver / Q000737:chemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013213:Starch
D013213:Starch; D000688:Amylose; D002784:Cholesterol