[Waldenström macroglobulinemia associated with cutaneous lesions and type I cryoglobulinemia].
Waldenström macroglobulinemia is a blood dyscrasia characterized by monoclonal proliferation of B cells in the bone marrow, lymph nodes, and spleen. Patients with this disease show elevated serum levels and tissue deposition of monoclonal immunoglobulin (Ig) M produced by these aberrant cells. We present the case of a patient with Waldenström macroglobulinemia who suffered cutaneous lesions resulting from deposition of k light chains of IgM and clinical manifestations secondary to associated type I cryoglobulinemia. We discuss the different pathological cutaneous processes caused by IgM in Waldenström macroglobulinemia.
del Olmo
J
J
Departamento de Dermatología, Clínica Universitaria de Navarra, Facultad de Medicina, Universidad de Navarra, Pamplona, Navarra, España.
España
A
A
Idoate
M A
MA
Panizo
C
C
D000368:Aged; D003449:Cryoglobulinemia / Q000150:complications*; D006801:Humans; D008297:Male; D012871:Skin Diseases / Q000150:complications*; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*