title: [Lipid profile disturbances are highly prevalent in Japanese-Brazilians].
abstract: High prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged>30 years. Hypercholesterolemia was defined as serum cholesterol>240 mg/dL, hypertriglyceridemia as values>150 mg/dL and low-HDL-C as values<40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7+/-196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1-26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total/HDL-cholesterol ratio was lower in women (4.23+/-0.68 vs. 4.40+/-0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.
authors.affiliation: Departamento de Medicina, EPM, Universidade Federal de São Paulo, São Paulo, SP, Brazil. antonela74@terra.com.br
authors.forename: Antonela F A
authors.initials: AF
authors.lastname: Siqueira
authors.forename: Helena A
authors.initials: HA
authors.lastname: Harima
authors.forename: Katsumi
authors.initials: K
authors.lastname: Osiro
authors.forename: Amélia T
authors.initials: AT
authors.lastname: Hirai
authors.forename: Suely G A
authors.initials: SG
authors.lastname: Gimeno
authors.forename: Sandra R G
authors.initials: SR
authors.lastname: Ferreira
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People / Q000706:statistics & numerical data*; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D001938:Brazil; D016009:Chi-Square Distribution; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D015228:Hypertriglyceridemia / Q000208:ethnology*; D007564:Japan / Q000208:ethnology; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids; D005947:Glucose