Fluorenes and styrenes by Au(I)-catalyzed annulation of enynes and alkynes.
Intermolecular annulation of enynes and propargyl esters to selectively produce styrenes or fluorenes is reported. The divergent arene syntheses involve a Au-catalyzed, two-pot, multistep process proceeding by cis-diastereoselective cyclopropanation, cycloisomerization, and, finally, annulation or elimination.
Gorin
David J
DJ
Department of Chemistry, University of California, Berkeley, California 94720, USA.
Watson
Iain D G
ID
Toste
F Dean
FD
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000138:chemical synthesis* / Q000737:chemistry
D000480:Alkynes; D005449:Fluorenes; D050607:Organogold Compounds; D013343:Styrenes; D006046:Gold