title: Diagnosis and management of subclavian vein thrombosis: three case reports and review of literature.
abstract: Axillosubclavian vein thrombosis is seen relatively infrequently in clinical practice when compared with lower limb deep-venous thrombosis; however, it is a condition that can result in significant morbidity if managed suboptimally. A multimodal treatment approach has been increasingly adopted with thrombolysis and/or thoracic outlet decompression being favored over anticoagulation alone, although the evidence base to support this approach is limited. In all, 3 cases are reported, which highlight numerous pertinent issues relating to the diagnostic and therapeutic options available.
authors.affiliation: Department of Surgery, Countess of Chester Hospital, Chester, United Kingdom. richsmith@doctors.org.uk
authors.forename: Richard A
authors.initials: RA
authors.lastname: Smith
authors.forename: Sameh K
authors.initials: SK
authors.lastname: Dimitri
mesh_terms: D000293:Adolescent; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D019299:Decompression, Surgical; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D013350:Subclavian Vein / Q000473:pathology / Q000601:surgery; D013901:Thoracic Outlet Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents