title: Otological findings among Nigerian children with sickle cell anaemia.
abstract: OBJECTIVE
  Various degrees of hearing loss have been associated with sickle cell anaemia, especially of the sensorineural type (SNHL). However, there is little information on hearing pattern among sickle cell children in Nigeria. This study is to determine the prevalence of sensorineural hearing loss (SNHL) among children with sickle cell anaemia (SCA).
  
  
  METHODS
  Eighty (80) stable children aged 4-15 with Hbss attending the pediatric sickle cell clinic and also 60 control patients with HbAA, matched for age, sex at the pediatric general medical clinic of the University of Ilorin teaching hospital, Ilorin, Nigeria, all had prospective study of their pure tone audiological assessment (PTA) and tympanometric evaluations done over a year period.
  
  
  RESULTS
  Their age range was 4-15 years with a mean of 9.4 for the Hbss and 9.7 for the control group. The male/female ratio was 1.3:1 and 1.5:1 for SCA and control subjects respectively. 25 subjects (50 ears) had abnormal audiograms among the SCA subjects and OME was the cause in 22 subjects and only three (3) had mild SNHL which was bilateral. However, in the control group 15 had abnormal audiograms and all were due to OME and none had SNHL. OME was bilateral in 19 subjects with SCA, two on the left and only one on the right. In the control group, 11 of the OME was bilateral and only four were on the left side. The prevalence of SNHL was 3.8% and OME was 27.5%.
  
  
  CONCLUSIONS
  We have found a prevalence rate for SNHL of 3.8% for 80 subjects with HbSS, and all cases have been a mild bilateral high frequency SNHL. Our findings suggested that SNHL is uncommon in early childhood, specifically during the years of language acquisition and early schooling. This could mean an age dependant prevalence rate of SNHL among SCA patients. However, no difference in the incidence of OME among both groups which can lead to educational difficulties from the resultant speech and language defects.
authors.affiliation: Department of Otorhinolaryngology, College of Health Sciences, University of Ilorin, Ilorin, Nigeria. alabibs@yahoo.com
authors.forename: Sulyman
authors.initials: S
authors.lastname: Alabi
authors.forename: Kolade
authors.initials: K
authors.lastname: Ernest
authors.forename: Paul
authors.initials: P
authors.lastname: Eletta
authors.forename: Adesina
authors.initials: A
authors.lastname: Owolabi
authors.forename: Abdul
authors.initials: A
authors.lastname: Afolabi
authors.forename: Olayinka
authors.initials: O
authors.lastname: Suleiman
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006314:Hearing Loss, Conductive / Q000150:complications / Q000175:diagnosis; D006319:Hearing Loss, Sensorineural / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009549:Nigeria