title: Comparative study between tramadol and dexamethasone as an admixture to bupivacaine in supraclavicular brachial plexus block.
abstract: This is a prospective, randomized, double blind study to evaluate the postoperative analgesia following supraclavicular brachial plexus block with Tramadol or Dexamethasone as an admixture to bupivacaine in upper extremity surgery. Total 60 patients of ASA I and II undergoing upper extremity surgery under brachial plexus block with Bupivacaine were randomly divided in to two groups; one group received Tramadol (2 mg/kg) and the other group received Dexamethasone (8 mg) as an admixture to Bupivacaine. The duration of postoperative analgesia was recorded in both groups using pain VAS score which was determined by maximum VAS score of 8-10 and when patient demands for additional analgesics. The mean duration of postoperative analgesia in the Dexamethasone group was 1028.00 minutes while in the tramadol group it was 453.17 minutes We concluded that Dexamethasone with local anaesthetic prolongs postoperative analgesia significantly than Tramadol (P<0.05) when used as admixture to local anaesthetic in brachial plexus block in upper extremity surgery.
authors.affiliation: Department of Anaesthesiology, Kathmandu Medical College, Kathmandu, Nepal. barashrestha@yahoo.co.in
authors.forename: B R
authors.initials: BR
authors.lastname: Shrestha
authors.forename: S K
authors.initials: SK
authors.lastname: Maharjan
authors.forename: S
authors.initials: S
authors.lastname: Shrestha
authors.forename: B
authors.initials: B
authors.lastname: Gautam
authors.forename: C
authors.initials: C
authors.lastname: Thapa
authors.forename: P B
authors.initials: PB
authors.lastname: Thapa
authors.forename: M R
authors.initials: MR
authors.lastname: Joshi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000698:Analgesia / Q000379:methods*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage; D002045:Bupivacaine / Q000008:administration & dosage*; D003907:Dexamethasone / Q000008:administration & dosage*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D011182:Postoperative Care / Q000379:methods; D011446:Prospective Studies; D020069:Shoulder Pain / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D014147:Tramadol / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D005938:Glucocorticoids; D014147:Tramadol; D003907:Dexamethasone; D002045:Bupivacaine