Microarray technology applied to the complex disorder of preeclampsia.
Preeclampsia is a life-threatening perinatal complication with unknown etiology. Microarray technology has characterized global gene expression in complex disorders such as preeclampsia. Nursing research and future practice may incorporate findings from microarray analyses to identify susceptibility to and prevent disease, to diagnose early, and to design and monitor personalized therapies. This overview of microarray technology, with emphasis on how it can inform genomics of preeclampsia, may provide concepts to improve future maternal-neonatal nursing care.
Founds
Sandra A
SA
Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, PA 15261, USA. safounds@comcast.net
Dorman
Janice S
JS
Conley
Yvette P
YP
D042241:Early Diagnosis; D005260:Female; D005820:Genetic Testing; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D011225:Pre-Eclampsia / Q000235:genetics* / Q000503:physiopathology / Q000517:prevention & control*; D011247:Pregnancy; D009626:Terminology as Topic