title: Central retinal vein occlusion associated with clomiphene-induced ovulation.
abstract: OBJECTIVE
  To report a case of central retinal vein occlusion associated with clomiphene citrate (CC).
  
  
  METHODS
  Case study.
  
  
  METHODS
  Ophthalmology clinic of an academic hospital.
  
  
  METHODS
  A 36-year-old woman referred from the infertility clinic for blurred vision.
  
  
  METHODS
  Ophthalmic examination after CC therapy.
  
  
  METHODS
  Central retinal vein occlusion after ovulation induction with CC.
  
  
  RESULTS
  A 36-year-old Chinese woman developed central retinal vein occlusion after eight courses of CC. A search of the literature on the thromboembolic complications of CC does not include this severe ophthalmic complication, although mild visual disturbance after CC intake is not uncommon.
  
  
  CONCLUSIONS
  This is the first reported case of central retinal vein occlusion after treatment with CC. Extra caution is warranted in treating infertility patients with CC, and patients should be well informed of this side effect before commencement of therapy.
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. vincent.leeyw@gmail.com
authors.forename: Vincent Y W
authors.initials: VY
authors.lastname: Lee
authors.forename: David T L
authors.initials: DT
authors.lastname: Liu
authors.forename: Chi-Lai
authors.initials: CL
authors.lastname: Li
authors.lastname: Hoi-Fan
authors.forename: Dennis S C
authors.initials: DS
authors.lastname: Lam
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000009:adverse effects*; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D010062:Ovulation Induction / Q000009:adverse effects*; D011859:Radiography; D012170:Retinal Vein Occlusion / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D016896:Treatment Outcome; D014221:Triamcinolone / Q000627:therapeutic use; D014786:Vision Disorders / Q000139:chemically induced; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D005300:Fertility Agents, Female; D005938:Glucocorticoids; D002996:Clomiphene; D014221:Triamcinolone