[Inhibit affection of resveratrol on the growth of Hep-2 cell line].
OBJECTIVE
To study the inhibitory effect of resveratrol on growth of human laryngeal cancer cell line, Hep-2.


METHODS
Count cell number under microscope, MTT assay was used to determine the cell growth inhibitory rate. Soft agar colony forming experiment was performed to observe the proliferation ability, before or after resveratrol treatment.


RESULTS
Resveratrol was able to depress cell growth and inhibit cell proliferation.


CONCLUSIONS
Resveratrol strongly inhibit Hep-2 cell proliferation in a time- and dose-dependent manner.
Li
Yunchuan
Y
Department of Otolaryngoloy-Head and Neck Surgery, Capital Medical University, Beijing, 100730, China. 1964liyunchuan@163.com
Xu
Yanwei
Y
Huang
Dan
D
Jiang
Linlin
L
Li
Kesen
K
D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D000077185:Resveratrol; D013267:Stilbenes / Q000494:pharmacology*
D013267:Stilbenes; D000077185:Resveratrol