title: A detector for a chronic implantable atrial tachyarrhythmia monitor.
abstract: Continuous long-term monitoring of atrial fibrillation (AF) and tachycardia (AT) is an unmet clinical need, which could be met with a chronically-implanted monitor. Improved therapeutic decisions based on accurate monitoring of parameters, such as daily AF/AT burden (hours/ day) may lead to improvements in clinical outcomes such as reduction in hospitalizations, symptoms, and strokes. This paper describes an AF/AT detector that detects AF as well as AT with an irregular ventricular response, and a supplementary AT detector for AT with more regular ventricular response. Seven databases with significant durations of AF, AT, and sinus rhythm were used to evaluate the performance of the detectors. All patient records with AF (N = 124) were detected by the AF/AT detector to have AF/AT burden with a mean, median, and 75 percentile of absolute error in burden detection of 8.8, 0, and 4 min, respectively. In patients having AF burden (= or > 10 min), the AF/AT detector was found to have burden accuracy within 20% of true burden in 96% of patients. The specificity was 94%, defined as follows: in patient records without AF/AT (N = 174), the percentage with AF/AT burden = or < 10 min in the 24-h recordings. The AF/AT detector underestimatesAT burden, thus degrading performance, in patients with significant amounts of AT with more regular ventricular response. The supplementary AT detector reduces the underestimation of AT while overestimating burden in patients without a significant amount of AT. The detectors described here could be implemented in an implantable monitor for accurate long-term AF/AT monitoring.
authors.affiliation: Medtronic, Inc., 8200 Coral Sea Street NE, MVN41, Moundsview, MN 55112 USA. shantanu.sarkar@medtronic.com
authors.forename: Shantanu
authors.initials: S
authors.lastname: Sarkar
authors.forename: David
authors.initials: D
authors.lastname: Ritscher
authors.forename: Rahul
authors.initials: R
authors.lastname: Mehra
mesh_terms: D000465:Algorithms; D001281:Atrial Fibrillation / Q000175:diagnosis*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D015716:Electrocardiography, Ambulatory / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D010363:Pattern Recognition, Automated / Q000379:methods*; D019736:Prostheses and Implants; D012815:Signal Processing, Computer-Assisted; D013612:Tachycardia, Ectopic Atrial / Q000175:diagnosis*