GID1-mediated gibberellin signaling in plants.
Gibberellin (GA) perception is mediated by GID1 (GA-INSENSITIVE DWARF1), a receptor that shows similarity to hormone-sensitive lipases. A key event in GA signaling is the degradation of DELLA proteins, which are negative regulators of GA response that interact with GID1 in a GA-dependent manner. This GID1-DELLA GA-perception system is conserved among vascular plants but is not found in the moss Physcomitrella patens. The identification of factors in GA signaling downstream of DELLA and the development of a new concept of DELLA function beyond its role as a repressor of GA signaling are important advances. DELLA proteins appear to have at least two other distinct roles: maintaining GA homeostasis and regulating cross-talk between GA and other plant hormones.
Hirano
Ko
K
Bioscience and Biotechnology Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Ueguchi-Tanaka
Miyako
M
Matsuoka
Makoto
M
D029681:Arabidopsis Proteins / Q000378:metabolism; D005875:Gibberellins / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D008954:Models, Biological; D015394:Molecular Structure; D063245:Plant Development; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000187:drug effects / Q000378:metabolism; D011485:Protein Binding; D011956:Receptors, Cell Surface / Q000378:metabolism*; D015398:Signal Transduction
D029681:Arabidopsis Proteins; C512225:GID1a protein, Arabidopsis; D005875:Gibberellins; D010940:Plant Proteins; D011956:Receptors, Cell Surface