Charge monitoring cell mass spectrometry.
An instrument to directly measure the charge carried by a cell or a microparticle as well as mass-to-charge ratio of the cell/microparticle was developed for rapid mass distribution measurement. A successful mass spectrum with a record high mass has been demonstrated. In this article, the details of the construction and operation of the charge monitoring cell mass spectrometer are reported. Examples are also given for demonstration and discussion.
Peng
Wen-Ping
WP
Genomics Research Center, Institute of Physics, and Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan, Republic of China.
Lin
Huan-Chang
HC
Chu
Ming-Lee
ML
Chang
Huan-Cheng
HC
Lin
Hsin-Hung
HH
Yu
Alice L
AL
Chen
Chung-Hsuan
CH
D002138:Calibration; D002470:Cell Survival; D002478:Cells, Cultured; D006801:Humans; D007477:Ions / Q000737:chemistry; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*
D007477:Ions