title: Adenoid cystic carcinoma of the parotid gland with temporal bone invasion.
abstract: OBJECTIVE
  To present our series of 16 patients with adenoid cystic carcinoma (ACC) of the parotid gland with temporal bone invasion.
  
  
  METHODS
  All patients treated at our institution between July 1988 and July 2004 with parotid gland ACC with temporal bone invasion.
  
  
  METHODS
  Preoperative radiographic assessment with combined surgical and radiation therapy treatment.
  
  
  METHODS
  Postoperative- or radiation-related complications and overall 2-, 5-, and 10-year survival.
  
  
  RESULTS
  The most common surgically related complications were new-onset cranial nerve deficits, whereas osteoradionecrosis of the bony external auditory canal was the most frequently noted complication associated with radiation therapy. The overall survival rates at 2, 5, and 10 years were 94, 75, and 60%, respectively.
  
  
  CONCLUSIONS
  Lateral cranial base access should be used in the extirpation of ACC of the parotid gland with temporal bone involvement.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood, Illinois, U.S.A. jleonet@lumc.edu
authors.forename: John P
authors.initials: JP
authors.lastname: Leonetti
authors.forename: Sam J
authors.initials: SJ
authors.lastname: Marzo
authors.forename: Neena
authors.initials: N
authors.lastname: Agarwal
mesh_terms: D000293:Adolescent; D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013506:Otologic Surgical Procedures; D010307:Parotid Neoplasms / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary*; D013701:Temporal Bone / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome