title: Sleep: dozy worms and sleepy flies.
abstract: Recent work on quiescent states in Caenorhabditis elegans suggests that worms exhibit behaviours reminiscent of satiety and sleep in mammals. At a molecular level, signalling through the EGF receptor and protein kinase G promotes quiescent states in both worms and flies, suggesting conserved mechanisms for sleep-like behaviours.
authors.affiliation: Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
authors.forename: Birgitta
authors.initials: B
authors.lastname: Olofsson
authors.forename: Mario
authors.initials: M
authors.lastname: de Bono
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D017869:Cyclic GMP-Dependent Protein Kinases / Q000378:metabolism; D004330:Drosophila / Q000502:physiology*; D066246:ErbB Receptors / Q000378:metabolism; D012528:Satiety Response / Q000502:physiology; D012890:Sleep / Q000502:physiology*
chemical_list: D066246:ErbB Receptors; D017869:Cyclic GMP-Dependent Protein Kinases