title: Narrowband shear wave generation by a Finite-Amplitude radiation force: The fundamental component.
abstract: A highly localized source of low-frequency shear waves can be created by the modulated radiation force resulting from two intersecting quasi-continuous-wave ultrasound beams of slightly different frequencies. In contrast to most other radiation force-based methods, these shear waves can be narrowband. Consequently, different frequency-dependent effects will not significantly affect their spectrum as they propagate within a viscoelastic medium, thereby enabling the viscoelastic shear properties of the medium to be determined at any given modulation frequency. This can be achieved by tracking the shear wave phase delay and change in amplitude over a specific distance. In this paper we explore the properties of short duration (dynamic) low-frequency shear wave propagation and study how the shear displacement field depends on the excitation conditions. Our investigations make use of the approximate Green's functions for viscoelastic media, and the evolution of such waves is studied in the spatiotemporal domain from a theoretical perspective. Although nonlinearities are included in our confocal source model, just the properties of the fundamental shear component are examined in this paper. We examine how the shear wave propagation is affected by the shear viscosity, the coupling wave, the spatial distribution of the force, the shear speed, and the duration of the modulated wave. A method is proposed for estimating the shear viscosity of a viscoelastic medium. In addition, it is shown how the Voigt model paremeters can be extracted from the frequency-dependent speed and attenuation.
authors.affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
authors.forename: Alexia
authors.initials: A
authors.lastname: Giannoula
authors.forename: Richard S C
authors.initials: RS
authors.lastname: Cobbold
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D003198:Computer Simulation; D003238:Connective Tissue / Q000000981:diagnostic imaging* / Q000502:physiology*; D004548:Elasticity; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D033081:Shear Strength; D013314:Stress, Mechanical