title: Occurrence of synchronous invasive lobular breast carcinoma and poorly differentiated ovarian carcinoma in a single peritoneal deposit.
abstract: The synchronous occurrence of breast and ovarian cancers within individual omental metastases has not been reported in the available medical literature. We report such a finding in a patient with previously diagnosed invasive lobular carcinoma of the right breast. After 5 years of surveillance and disease-free interval, there was development of ovarian cancer, ascites and peritoneal metastases. Ultrasound-guided biopsy of a peritoneal metastasis confirmed dual histology from breast and ovarian carcinoma. Despite the presence of a prolonged disease-free survival from the primary breast cancer, the subsequent finding of advanced ovarian cancer highlights the potential diagnostic and therapeutic dilemmas which persist in the management of these patients.
authors.affiliation: Department of Radiology, Milton Keynes Hospital, Milton Keynes, UK.
authors.forename: R
authors.initials: R
authors.lastname: Syed
authors.forename: S A
authors.initials: SA
authors.lastname: Nazir
authors.forename: K Y
authors.initials: KY
authors.lastname: Lwin
authors.forename: P
authors.initials: P
authors.lastname: Bose
authors.forename: P
authors.initials: P
authors.lastname: Evans
authors.forename: K
authors.initials: K
authors.lastname: Choji
mesh_terms: D001201:Ascites / Q000209:etiology; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000175:diagnosis* / Q000556:secondary*; D018275:Carcinoma, Lobular / Q000175:diagnosis* / Q000556:secondary*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology