Two new sesquiterpenoids from the soft coral Sinularia polydactyla (Ehreberg).
Two new sesquiterpenoids, polydactins A (1) and B (2) and a known sesquiterpene, 10alpha-hydroxycadin-4-en-15-al (3), were isolated from the soft coral Sinularia polydactyla (Ehreberg). Their structures were determined mainly by spectroscopic methods. Polydactin A (1) showed moderate cytotoxic activities against human oral epidermoid carcinoma cell lines (KB) and human breast carcinoma (MCF) tumour cell lines (in vitro).
Zhang
Cui-Xian
CX
School of Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Zhu
Chen-Chen
CC
Yan
Su-Jun
SJ
Li
Jun
J
Su
Jing-Yu
JY
Liang
Yong-Ju
YJ
Yang
Xiao-Ping
XP
Zheng
Kang-Cheng
KC
Zeng
Long-Mei
LM
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
D012717:Sesquiterpenes