title: A Caenorhabditis elegans genetic-interaction map wiggles into view.
abstract: Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation.
authors.affiliation: Center for Genomics and Systems Biology and Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA. kcg1@nyu.edu
authors.forename: Kristin C
authors.initials: KC
authors.lastname: Gunsalus
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D029742:Caenorhabditis elegans Proteins / Q000235:genetics* / Q000378:metabolism; D049751:Genome, Helminth; D025941:Protein Interaction Mapping / Q000379:methods*; D015398:Signal Transduction
chemical_list: D029742:Caenorhabditis elegans Proteins