Correlation of intra-tumour heterogeneity on 18F-FDG PET with pathologic features in non-small cell lung cancer: a feasibility study.
We evaluated the feasibility to correlate intra-tumour heterogeneity as visualized on 18F-FDG PET with histology for NSCLC. For this purpose we used an ex-vivo model. The procedure was feasible in all operated patients. We have shown that this method is suitable for correlating intra-tumour heterogeneity in tracer uptake with histology.
van Baardwijk
Angela
A
Department of Radiation Oncology (MAASTRO), GROW , University Hospital Maastricht, Maastricht, The Netherlands. angela.vanbaardwijk@maastro.nl
Bosmans
Geert
G
van Suylen
Robert Jan
RJ
van Kroonenburgh
Marinus
M
Hochstenbag
Monique
M
Geskes
Gijs
G
Lambin
Philippe
P
De Ruysscher
Dirk
D
D000328:Adult; D000368:Aged; D001706:Biopsy; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy*; D016009:Chi-Square Distribution; D005240:Feasibility Studies; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18