title: Separating the left cardiac ventricle from the atrium in short axis MR images using the equation of the atrioventricular plane.
abstract: Short axis (SA) images obtained from cardiac magnetic resonance imaging are used to advantage in the calculation of important clinical parameters such as the ejection fraction and stroke volume (SV). A prerequisite for these calculations is the separation of the left ventricle and the left atrium. When only using the information seen in the SA images this separation can be a source of error due to the through-plane motion of the basal part of the left ventricle. In this study a method is proposed where the separation of the left ventricle and the atrium is performed by identifying the intersections of the atrioventricular plane in the SA images. The equation of the atrioventricular plane was determined in both systole and diastole using long axis and four chamber image views. Stroke volumes were measured in 20 patients using SA images where the endocardium had been delineated. The SV obtained using the new method was compared with quantitative flow measurements and the conventional technique for calculation of SV from SA images, respectively. The agreement of SV was, according to Bland-Altman analysis, 2.0 ml (95% CI -12.0 to 15.9 ml) in comparison with the flow measurements and 2.2 ml (95% CI -9.2 to 13.6 ml) compared to the conventional method. Inter- and intra-observer variability, when using the new proposed method, was small. This study shows that the identification of the left atrioventricular plane in SA images can be used in the separation of the left atrium and ventricle.
authors.affiliation: Department of Biomedical Engineering, Orebro University Hospital, Orebro, Sweden. per.thunberg@orebroll.se
authors.forename: Per
authors.initials: P
authors.lastname: Thunberg
authors.forename: Kent
authors.initials: K
authors.lastname: Emilsson
authors.forename: Peter
authors.initials: P
authors.lastname: Rask
authors.forename: Anders
authors.initials: A
authors.lastname: Kähäri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006325:Heart Atria / Q000033:anatomy & histology*; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000033:anatomy & histology / Q000502:physiology; D015588:Observer Variation; D013318:Stroke Volume; D016276:Ventricular Function; D016277:Ventricular Function, Left