title: [Development of the technology of the substance of davikol and standardization].
abstract: Among wide assortment of pharmaceutical remedies, that use modern medicine as a weapon against different diseases, special place belongs to the ophthalmic pharmaceutical forms, and their development presents independent branch of pharmaceutical technology. Recently, as a reason of various diseases and among them ophthalmic problems, is considered free radicals and reactions with their participation. Protection of the organism from such diseases presents a main goal of antioxidant system. Nowadays, special attention is paid to the natural antioxidants. On the basis of the natural honey technology of eye drops davikol with antioxidant activity have been developed. The objective of our study has been the development of the substance of prolonged pharmaceutical dosage form davikol - eye ophthalmic drops and its standardization. The qualitative and quantitative methods were developed. It is concluded that the optimal method of drying of davikol is sublimation. Dry powder (active substance) davikol was obtained; quality characteristics were identified.
authors.affiliation: Tbilisi State Medical University, Department of Pharmaceutical Technology, Tbilisi, Georgia.
authors.forename: A
authors.initials: A
authors.lastname: Bakuridze
authors.forename: D
authors.initials: D
authors.lastname: Shengelia
authors.forename: N
authors.initials: N
authors.lastname: Kurdiani
authors.forename: G
authors.initials: G
authors.lastname: Mikaia
authors.forename: N
authors.initials: N
authors.lastname: Karanadze
mesh_terms: D018926:Anti-Allergic Agents / Q000737:chemistry*; D006801:Humans; D009883:Ophthalmic Solutions / Q000737:chemistry*; D009885:Ophthalmology / Q000295:instrumentation*; D008517:Phytotherapy / Q000379:methods*
chemical_list: D018926:Anti-Allergic Agents; D009883:Ophthalmic Solutions