title: Cytomegalovirus infection and new-onset post-transplant diabetes mellitus.
abstract: We analyzed data from all consecutive kidney transplant patients at our institution between April 2003 and October 2006. We found 15 cases of late-onset cytomegalovirus (CMV) infection, two of which developed concurrent post-transplant diabetes mellitus (PTDM). In these two cases, PTDM was transient and normal glucose tolerance was achieved after an eight-wk therapeutic course of oral valganciclovir. These findings suggest that CMV infection after organ transplantation may be associated with concurrent PTDM. The distinct causative relationship is yet to be determined.
authors.affiliation: Transplantation Center, Institute of Microbiology, and Service of Endocrinology, CHUV, Lausanne, Switzerland.
authors.forename: En-Ling
authors.initials: EL
authors.lastname: Leung Ki
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Venetz
authors.forename: Pascal
authors.initials: P
authors.lastname: Meylan
authors.forename: Fréderic
authors.initials: F
authors.lastname: Lamoth
authors.forename: Juan
authors.initials: J
authors.lastname: Ruiz
authors.forename: Manuel
authors.initials: M
authors.lastname: Pascual
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000821:virology*; D005260:Female; D015774:Ganciclovir / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000821:virology*; D000077562:Valganciclovir
chemical_list: D000998:Antiviral Agents; D000077562:Valganciclovir; D015774:Ganciclovir