title: [Experience with complex treatment for childhood amblyopia].
abstract: The effects of mexidole on the higher efficiency of treatment for diseases involving the visual nerve apparatus and on the achievement of stable visual function were studied in children. The study covered a study group of 36 children aged 5 to 12 years (mean 8.50 +/- 0.56 years) who had amblyopla of various genesis. A control group comprised 30 patients (mean age was 8.20 +/- 0.56 years) who had also amblyopia of various genesis and 25 healthy children (mean age was 8.20 +/- 0.63 years). The patients of the first two groups received the similar course pleoptic treatment. Those of the study group were additionally given mexidole by the conventional regimen. Mexidole used in children with amblyopia enhanced the efficiency of complex pleoptic treatment in 83% of cases and long maintained the visual functions achieved during stimulation. The agent has a positive effect on the values of visually evoked potentials.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Smirnova
authors.forename: O V
authors.initials: OV
authors.lastname: Shishova
authors.forename: K V
authors.initials: KV
authors.lastname: Smirnov
mesh_terms: D000550:Amblyopia / Q000188:drug therapy* / Q000503:physiopathology; D000975:Antioxidants / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005074:Evoked Potentials, Visual / Q000187:drug effects; D005500:Follow-Up Studies; D006801:Humans; D010847:Picolines / Q000627:therapeutic use*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000975:Antioxidants; D010847:Picolines; C070020:emoxypine succinate