Thromboelastographic tracings in retired racing greyhounds and in non-greyhound dogs.
BACKGROUND
Bleeding disorders in patients with normal coagulation test results are frequently reported in Greyhounds. The purpose of this study was to compare Greyhounds to non-Greyhounds by thromboelastography (TEG).


OBJECTIVE
TEG parameters in Greyhounds are different from those in non-Greyhounds.


METHODS
Forty-three healthy dogs (28 Greyhounds and 15 non-Greyhounds) based on the results of physical examination, CBC, activated partial thromboplastin time, prothrombin time, fibrinogen, and platelet count.


METHODS
Recalcified citrated native TEGs were performed in both groups; data were compared using Student's, Mann-Whitney, and Pearson's statistical tests.


RESULTS
In Greyhounds, mean +/- SD were as follows: R-time 4.3 +/- 1.7 minutes, K-time 3.8 +/- 1.4 minutes, angle (alpha) 50.0 +/- 8.0 degrees , maximum amplitude (MA) 47.6 +/- 5.6 mm, clot strength (G) 4,647 +/- 1,097 dyn/cm2, and percent lysis at 60 minutes (LY60) 2.8 +/- 5.0%. In the non-Greyhounds they were R-time 3.7 +/- 1.6 minutes, K-time 2.5 +/- 0.9 minutes, angle 59.8 +/- 7.0 degrees , MA 53.1 +/- 5.6 mm, G 5,811 +/- 1,256 dyn/cm2, and LY60 3.1 +/- 2.5%. All parameters were significantly different between the groups, except for R-time and LY60.


CONCLUSIONS
In Greyhounds, clotting kinetics are slower and clot strength are weaker than in non-Greyhounds, supporting the increased tendency to bleed observed after minor trauma or surgical procedures in the breed. The findings may also be attributed to blood viscosity or to the concentration of citrate in the sample (ie, Greyhounds have higher hematocrit and less plasma per unit volume).
Vilar
P
P
Department of Veterinary Clinical Sciences and Veterinary Teaching Hospital, The Ohio State University, Columbus, OH 43210, USA. vilarsaavedra.1@osu.edu
Couto
C G
CG
Westendorf
N
N
Iazbik
C
C
Charske
J
J
Marín
L
L
D000818:Animals; D001777:Blood Coagulation / Q000235:genetics*; D001780:Blood Coagulation Tests / Q000662:veterinary; D001947:Breeding; D004285:Dogs / Q000097:blood*; D005260:Female; D006487:Hemostasis / Q000235:genetics; D008297:Male; D012016:Reference Values; D013916:Thrombelastography / Q000662:veterinary*