Diversity of the Cryptococcus neoformans-Cryptococcus gattii species complex.
More than 110 years of study of the Cryptococcus neoformans and Cryptococcus gattii species complex has resulted in an enormous accumulation of fundamental and applied biological and clinical knowledge. Recent developments in our understanding of the diversity within the species complex are presented, emphasizing the intraspecific complexity, which includes species, microspecies, hybrids, serotypes and genotypes. Each of these may have different roles in disease. An overview of obsolete and current names is presented.
Bovers
Marjan
M
Yeast Research Group, CBS Fungal Diversity Centre, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
Hagen
Ferry
F
Boekhout
Teun
T
D000818:Animals; D003453:Cryptococcosis / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission / Q000662:veterinary; D003454:Cryptococcus / Q000145:classification* / Q000502:physiology; D003455:Cryptococcus neoformans / Q000145:classification / Q000502:physiology; D049770:Genes, Mating Type, Fungal; D005838:Genotype; D006801:Humans; D006824:Hybridization, Genetic; D001239:Inhalation; D008172:Lung Diseases, Fungal / Q000382:microbiology / Q000635:transmission; D011003:Ploidies; D012100:Reproduction, Asexual; D012703:Serotyping; D013045:Species Specificity; D013172:Spores, Fungal; D014774:Virulence; D015047:Zoonoses