title: A long-standing incomprehensible matter of obstetrics: meconium-stained amniotic fluid, a new approach to reason.
abstract: OBJECTIVE
  We sought to determine whether meconium-stained amniotic fluid is based on chronic hypoxia or not? In case of chronic hypoxia, higher red blood cell (Rbc) count and/or total hemoglobin levels (Hgb) and/or higher fetal hemoglobin (HbF) and/or lower adult hemoglobin (HbA) levels were expected when compared with controls.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Obstetric unit of a tertiary ministry of health hospital.
  
  
  METHODS
  Fifty singleton pregnancies with meconium-stained amniotic fluid and 50 singleton pregnancies with clear amniotic fluid at all stages of labor.
  
  
  METHODS
  Umbilical cord blood samples were collected for determination of total blood parameters and hemoglobin electrophoresis.
  
  
  METHODS
  Red blood cell count, total hemoglobin, fetal and adult hemoglobin contents (HbF and HbA).
  
  
  RESULTS
  Red blood cell count, total hemoglobin, fetal hemoglobin (HbF) and adult hemoglobin (HbA) contents were not different between meconium stained and clear amniotic fluid groups.
  
  
  CONCLUSIONS
  These results suggest that meconium passage may not be associated with chronic fetal hypoxia as demonstrated by similar red blood cell count, total hemoglobin values and fetal hemoglobin (HbF) and adult hemoglobin (HbA) contents.
authors.affiliation: Department of Obstetrics and Gynecology, Dr.Zekai Tahir Burak Woman Health, Education and Research, Hospital, Saime kadin mah. calikavak sok. 22/4, abidinpasa, Mamak/Ankara, Turkey. adnan0013@yahoo.com
authors.forename: Adnan
authors.initials: A
authors.lastname: Simsek
authors.forename: Sevki
authors.initials: S
authors.lastname: Celen
authors.forename: Mine
authors.initials: M
authors.lastname: Islimye
authors.forename: Nuri
authors.initials: N
authors.lastname: Danisman
authors.forename: Umran
authors.initials: U
authors.lastname: Buyukkagnici
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry*; D016022:Case-Control Studies; D004906:Erythrocyte Count; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005319:Fetal Hemoglobin / Q000032:analysis*; D005311:Fetal Hypoxia / Q000097:blood / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008470:Meconium / Q000737:chemistry*; D011247:Pregnancy
chemical_list: D005319:Fetal Hemoglobin