A case of Stevens-Johnson syndrome possibly induced by amifostine during radiotherapy.
Skin reactions to amifostine are considered to be rare. Here we describe the case of a patient who developed a severe skin eruption (Stevens-Johnson syndrome) during radiotherapy probably due to amifostine. As in most of the patients described so far, the worst lesions were located in the skin areas previously treated with radiotherapy.
Zollo
Enrico
E
Radiotherapy Unit, Gaetano Rummo Hospital, Benevento, Italy.
Cusano
Francesco
F
Argenone
Angela
A
Cusano
Carlo Ivan
CI
Pelosi
Patrizia
P
Pironti
Teresa
T
Spacagna
Ettore
E
Viscusi
Alfonso
A
Lioce
Marco
M
D000368:Aged; D004999:Amifostine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D008297:Male; D011837:Radiation-Protective Agents / Q000008:administration & dosage / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000188:drug therapy
D011837:Radiation-Protective Agents; D004999:Amifostine