title: [Non alcoholic fatty liver disease: treatment with soluble fibres].
abstract: The pilot study evaluated the efficiency of oral soluble fibers to treat patients with nonalcoholic fatty liver disease. Twelve patients received 10 g/day of soluble fibers during 3 months. After the treatment 100% of patients presented reduction in body mass index, waist circumference and insulin resistance index. In 66.7% of the patients were observed reduction of the cholesterol levels and 75% presented normal liver enzymes (AST, ALT, and GGT). The present study suggests that oral soluble fibers may be useful to control risk factors and liver enzymes in patients with nonalcoholic fatty liver disease. However, future studies with histological controls are considered necessary.
authors.affiliation: Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brazil. raquelrocha2@yahoo.com.br
authors.forename: Raquel
authors.initials: R
authors.lastname: Rocha
authors.forename: Helma P
authors.initials: HP
authors.lastname: Cotrim
authors.forename: Ana Cristina
authors.initials: AC
authors.lastname: Siqueira
authors.forename: Shirley
authors.initials: S
authors.lastname: Floriano
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D004043:Dietary Fiber / Q000008:administration & dosage*; D019587:Dietary Supplements; D005234:Fatty Liver / Q000097:blood / Q000178:diet therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010865:Pilot Projects; D000637:Transaminases / Q000097:blood*; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood*; D049629:Waist-Hip Ratio
chemical_list: D004043:Dietary Fiber; D014280:Triglycerides; D002784:Cholesterol; D000637:Transaminases