Capecitabine induced inflammation of actinic keratoses.
Capecitabine, an oral prodrug of 5-fluorouracil, is a systemic chemotherapeutic agent used in the treatment of metastatic breast and colon cancer. Patients undergoing capecitabine therapy may experience inflammation and irritation of existing actinic keratoses. Oncologists and dermatologists alike should be aware of this side effect.
Krathen
M
M
Department of Dermatology, Hospital of University of Pennsylvania, Philadelphia, USA. michael.krathen@gmail.com
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D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000556:secondary; D000069287:Capecitabine; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007249:Inflammation / Q000139:chemically induced* / Q000188:drug therapy; D007642:Keratosis / Q000209:etiology; D014466:Ultraviolet Rays / Q000009:adverse effects
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil