Novel treatment of atrophic rhinitis: early results.
The aim of this randomized control trial, performed at a tertiary referral hospital, was to compare the therapeutic effectiveness of two novel treatment modalities, oral rifampicin and submucosal placentrex injection, in randomly selected patients of primary atrophic rhinitis regarding objective, subjective and histopathological improvement. Patients treated with oral rifampicin showed most promising results regarding objective, subjective and histopathological improvement with maximum disease-free interval on regular follow-up as compared to submucosal placentrex injections.
Jaswal
Abhishek
A
Calcutta National Medical College, 24 Gorachand Road, Kolkata 700014, India. abhishekjaswal@rediffmail.com
Jana
Avik Kumar
AK
Sikder
Biswajit
B
Nandi
Tapan K
TK
Sadhukhan
Sanjoy Kumar
SK
Das
Anjan
A
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D001706:Biopsy; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage*; D010924:Placental Extracts / Q000008:administration & dosage*; D012222:Rhinitis, Atrophic / Q000188:drug therapy* / Q000473:pathology; D012293:Rifampin / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
D019384:Nucleic Acid Synthesis Inhibitors; D010924:Placental Extracts; D012293:Rifampin