title: Methodology and application of clinical trials in radiology: self-assessment module.
abstract: The educational objectives of this self-assessment module are for the participant to understand the differences between cohort and case-control studies in radiology, to understand the advantages of randomized controlled trials over observational studies, to understand the basic principles underlying the use of imaging examinations for screening asymptomatic populations for particular diseases, and to understand the biases associated with the use of survival statistics in the evaluation of screening.
authors.affiliation: Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA..
authors.forename: William C
authors.initials: WC
authors.lastname: Black
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Krupinski
authors.forename: Annemarie
authors.initials: A
authors.lastname: Relyea-Chew
authors.forename: Felix S
authors.initials: FS
authors.lastname: Chew
mesh_terms: D015982:Bias; D015986:Confounding Factors, Epidemiologic; D019317:Evidence-Based Medicine; D006801:Humans; D008403:Mass Screening / Q000592:standards; D011871:Radiology / Q000379:methods* / Q000592:standards*; D016032:Randomized Controlled Trials as Topic / Q000379:methods* / Q000592:standards*; D012107:Research Design / Q000592:standards; D016019:Survival Analysis