Synthesis of fluorinated dienes by palladium-catalyzed coupling reactions.
The synthesis of partly fluorinated 1,3- and 1,4-dienes by palladium-catalyzed coupling makes these compounds available on the laboratory scale. Several catalyst systems were tested to maximize the yields and minimize the by-products. The molecular structures of 1,1,2,4,4-pentafluorobutadiene, chloro(N,N'-tetramethylethylenediamine)(trifluorovinyl)zinc, PCy(2)R, and P(O)Cy(2)R (Cy=cyclohexyl, R=2-(1-naphthyl)phenyl) were elucidated by X-ray crystallography.
Akkerman
Floris A
FA
Fachbereich Biologie, Chemie, Pharmazie, Institut für Chemie und Biochemie: Anorganische und Analytische Chemie, Freie Universität Berlin, Fabeckstrasse 34-36, D-14195 Berlin, Germany.
Kickbusch
Rainer
R
Lentz
Dieter
D
D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D006844:Hydrocarbons, Cyclic / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D006844:Hydrocarbons, Cyclic; D005461:Fluorine; D010165:Palladium