title: Leiomyomatous hamartoma: report of two cases and review of the literature.
abstract: Two cases of leiomyomatous hamartoma (LH) in patients of Latin ancestry are reported here. The first lesion was detected on the incisive papilla of a 19-year-old woman; this is an unusual age because these lesions are commonly observed during the first years of life. The second lesion found on the middle-dorsum of the tongue was observed in a 5-month-old boy. The diagnosis was based on the histopathological appearance and confirmed by immunohistochemistry with positivity for smooth muscle actin, muscle-specific actin, S-100 protein and desmin. To date, only 16 cases have been reported in the English-language literature. Controversial epidemiological data, histogenesis, clinical/histopathological features, and differential diagnosis are discussed herein.
authors.affiliation: Oral Pathology Department, School of Dentistry, Universidad Nacional Autónoma de México, Distrito Federal, Mexico.
authors.forename: Mario
authors.initials: M
authors.lastname: Nava-Villalba
authors.forename: Fabián
authors.initials: F
authors.lastname: Ocampo-Acosta
authors.forename: Alejandro
authors.initials: A
authors.lastname: Seamanduras-Pacheco
authors.forename: Beatriz C
authors.initials: BC
authors.lastname: Aldape-Barrios
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005882:Gingival Diseases / Q000473:pathology* / Q000601:surgery; D006222:Hamartoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery; D008297:Male; D014060:Tongue Diseases / Q000473:pathology* / Q000601:surgery