title: Spontaneous perforation in the upper oesophagus resulting from ulcer in heterotopic gastric mucosa.
abstract: Heterotopic gastric mucosa (HGM) can be found throughout the entire gastrointestinal tract, more frequently in the cervical oesophagus. Macroscopic HGM is named inlet patch (IP). The great majority of IPs are asymptomatic and discovered incidently during oesophageal endoscopy performed for another pathology. However, complications can occur. Among these, perforation is extremely rare. We report a case of a 27-year old man who presented with a perforation of an upper oesophageal ulcer arising from an IP. The diagnosis was made during endoscopy and confirmed with biopsy of the tissue surrounding the perforation, showing histologic modifications consistent with heterotopic gastric mucosa. Medical treatment using a proton pump inhibitor and antibiotics delivered with a gastric tube was advocated. The perforation was closed at day 7 and plasma Argon coagulation of the inlet patch was performed two months later. Annual endoscopy has been normal for three years.
authors.affiliation: CHU A. Michallon, Otorhinolaryngology-Head and Neck Surgery Department, F-38043 Grenoble 09, France. Crighini@chu-grenoble.fr
authors.forename: C A
authors.initials: CA
authors.lastname: Righini
authors.forename: Cl
authors.initials: C
authors.lastname: Faure
authors.forename: A
authors.initials: A
authors.lastname: Karkas
authors.forename: S
authors.initials: S
authors.lastname: Schmerber
authors.forename: E
authors.initials: E
authors.lastname: Reyt
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001706:Biopsy; D002828:Choristoma / Q000150:complications*; D004935:Esophageal Diseases / Q000150:complications*; D004939:Esophageal Perforation / Q000209:etiology*; D004945:Esophagoscopy; D005500:Follow-Up Studies; D005753:Gastric Mucosa; D006801:Humans; D008297:Male; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D014456:Ulcer / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors