[The effect of low-molecular-weight heparin on the late follow-up results of the combined and complex treatment of patients with rectal cancer].
The late follow-up results of combined and complex treatment of 305 patients, suffering cancer recti, were analyzed. After the operation in 250 (82%) patients the anticoagulants were administered, including the low-molecular-weight heparin (calcium nadroparine)--129 (42.3%), and nonfractionized heparin--in 121 (39.7%). In 55 (18%) patients the complex and combined treatment was conducted, according to the present standards, without application of anticoagulants. There was proved, that administration of calcium nadroparine in combined and complex treatment of patients, suffering cancer recti, had promoted the patients three-year and five-year survival indices increase due to reduction of the tumors generalization.
Leshchenko
Iu M
IuM
Miasoiedov
D V
DV
Oliĭnichenko
H P
HP
Koshel'
K V
KV
Iatsenko
S M
SM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000601:surgery
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight