title: Evaluation of mulitprobe radiofrequency technology in a porcine model.
abstract: OBJECTIVE
  We evaluated two new radiofrequency devices in an in vivo porcine model.
  
  
  METHODS
  Multiprobe radiofrequency ablation (RFA) was used in a porcine model with an impedance-based algorithm in one experiment and clustered probes with and without switcher controllers in another; a Pringle maneuver was used with half of the ablations.
  
  
  RESULTS
  The impedance experiment included 13 ablations, with a mean length of 7.0 cm and width of 2.9 cm (95% CI) and an average time of 596 s. Ablation volumes were significantly larger (54.1+/-11.7 cc(3) vs 34.9+/-4.8 cc(3), p<0.05) and ablation times were significantly shorter (359 s vs 834 s, p<0.05) for the Pringle group compared with the No Pringle group, respectively. The switcher controller experiment included 34 RFAs. Diameter (mm) (51.4 vs 40.3, p<0.0001), surface area (cm(2)) (22.4 vs 16.0, p<0.0002), and volume (cc) (66.1 vs 36.9, p<0.0001) were significantly larger for the combination probes with switcher controller compared with clustered probes, respectively. Ablation volumes for the Pringle vs No Pringle groups in the combination probes were 68.0 cc vs 64.3 cc and for the clustered probes 40.1 cc vs. 33.7 cc, respectively.
  
  
  CONCLUSIONS
  Multiprobe ablations using RFA are promising technologies that need further study to evaluate their clinical utility.
authors.affiliation: Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA.
authors.forename: William W
authors.initials: WW
authors.lastname: Hope
authors.forename: Jason M
authors.initials: JM
authors.lastname: Arru
authors.forename: Jason Q
authors.initials: JQ
authors.lastname: McKee
authors.forename: Dennis
authors.initials: D
authors.lastname: Vrochides
authors.forename: Bassam
authors.initials: B
authors.lastname: Aswad
authors.forename: Caroline J
authors.initials: CJ
authors.lastname: Simon
authors.forename: Damian E
authors.initials: DE
authors.lastname: Dupuy
authors.forename: David A
authors.initials: DA
authors.lastname: Iannitti