Plasmid segregation: is a total understanding within reach?
Recent in vitro and in vivo studies of the proteins responsible for the active partitioning of bacterial plasmids suggest that it will be possible to develop a quantitative, molecular understanding of this form of DNA segregation.
Needleman
Daniel J
DJ
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. Daniel_Needleman@hms.harvard.edu
D000199:Actins / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism; D020090:Chromosome Segregation / Q000502:physiology*; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D027101:DNA Topoisomerase IV / Q000378:metabolism; D004269:DNA, Bacterial / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000378:metabolism; D010957:Plasmids / Q000378:metabolism / Q000502:physiology*; D012097:Repressor Proteins / Q000378:metabolism
D000199:Actins; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C471255:ParM protein, E coli; C086169:ParR protein, bacteria; D012097:Repressor Proteins; D027101:DNA Topoisomerase IV