title: Fibrosis in systemic sclerosis.
abstract: This article reviews current understanding of the pathophysiology of fibrosis in systemic sclerosis. It highlights recent discoveries, insights, and emerging research, and potential opportunities for the development of targeted antifibrotic therapies.
authors.affiliation: Division of Rheumatology, Northwestern University Feinberg School of Medicine, McGaw 2300, 240 East Huron Street, Chicago IL 60611-2909, USA. j-varga@northwestern.edu
authors.forename: John A
authors.initials: JA
authors.lastname: Varga
authors.forename: Maria
authors.initials: M
authors.lastname: Trojanowska
mesh_terms: D000818:Animals; D003094:Collagen / Q000378:metabolism*; D004195:Disease Models, Animal; D005347:Fibroblasts / Q000502:physiology; D005355:Fibrosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D051379:Mice; D020286:Pericytes / Q000502:physiology; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000503:physiopathology*
chemical_list: D003094:Collagen