[Transcription factor AP-1 components as a psoriasis candidate genes].
Psoriasis is an autoimmune multifactorial dermatological disease frequently occured in European population. As for other multifactorial genetic diseases success in psoriasis treatment may be achieved due to determination of molecular genetic mechanisms of pathogenesis triggering and psoriasis candidate genes and proteins searching as targets for drugs. Using bioinformatic analysis of transcriptome data AP-1 transcriptional factor components were revealed as psoriasis candidate genes.
Pirusian
E S
ES
Nikol'skaia
T A
TA
Abdeev
R M
RM
Bruskin
S A
SA
D020869:Gene Expression Profiling; D020022:Genetic Predisposition to Disease; D006801:Humans; D011565:Psoriasis / Q000235:genetics* / Q000378:metabolism; D018808:Transcription Factor AP-1 / Q000235:genetics / Q000378:metabolism*
D018808:Transcription Factor AP-1