title: Macrolactin S, a novel macrolactin antibiotic from marine Bacillus sp.
abstract: A new 24-membered ring lactone, macrolactin S, was isolated from a culture broth of marine Bacillus sp. and its structure was established by various spectral analyses. Macrolactin S is the first macrolactin hydroxylated at C-12. Besides, the known compounds macrolactin A and macrolactin B were also isolated, which were elucidated on the basis of spectral data analyses and literature data comparison. They exhibited antibacterial activity against E. coli and S. aureus.
authors.affiliation: Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, PR China.
authors.forename: X L
authors.initials: XL
authors.lastname: Lu
authors.forename: Q Zh
authors.initials: QZh
authors.lastname: Xu
authors.forename: Y H
authors.initials: YH
authors.lastname: Shen
authors.forename: X Y
authors.initials: XY
authors.lastname: Liu
authors.forename: B H
authors.initials: BH
authors.lastname: Jiao
authors.forename: W D
authors.initials: WD
authors.lastname: Zhang
authors.forename: K Y
authors.initials: KY
authors.lastname: Ni
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001407:Bacillus / Q000737:chemistry*; D018942:Macrolides / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; C532687:macrolactin S