title: Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).
abstract: Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C ( 1), axinastatin 5 ( 5), bengazoles A ( 6), B ( 7), and E ( 8), manzamine A ( 10), jaspamide ( 11), and neoechinulin A ( 19) has been summarized.
authors.affiliation: Department of Chemstry and Biochemistry, Arizona State University, Tempe, Arizona 85287-2404, USA. bpettit@asu.edu
authors.forename: George R
authors.initials: GR
authors.lastname: Pettit
authors.forename: Fiona
authors.initials: F
authors.lastname: Hogan
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Xu
authors.forename: Rui
authors.initials: R
authors.lastname: Tan
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Nogawa
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Cichacz
authors.forename: Robin K
authors.initials: RK
authors.lastname: Pettit
authors.forename: Jiang
authors.initials: J
authors.lastname: Du
authors.forename: Qing-Hua
authors.initials: QH
authors.lastname: Ye
authors.forename: Gordon M
authors.initials: GM
authors.lastname: Cragg
authors.forename: Cherry L
authors.initials: CL
authors.lastname: Herald
authors.forename: Michael S
authors.initials: MS
authors.lastname: Hoard
authors.forename: Animesh
authors.initials: A
authors.lastname: Goswami
authors.forename: Justin
authors.initials: J
authors.lastname: Searcy
authors.forename: Larry
authors.initials: L
authors.lastname: Tackett
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Doubek
authors.forename: Lee
authors.initials: L
authors.lastname: Williams
authors.forename: John N A
authors.initials: JN
authors.lastname: Hooper
authors.forename: Jean M
authors.initials: JM
authors.lastname: Schmidt
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Chapuis
authors.forename: Denise N
authors.initials: DN
authors.lastname: Tackett
authors.forename: Felicia
authors.initials: F
authors.lastname: Craciunescu
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D047630:Depsipeptides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008386:Marine Biology; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010879:Piperazines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D002227:Carbazoles; D047630:Depsipeptides; D026121:Indole Alkaloids; D010080:Oxazoles; D010456:Peptides, Cyclic; D010879:Piperazines; C529255:axinastatin 5; C519397:bengazole A; C529257:bengazole B; C529256:bengazole E; C490266:neoechinulin A; C057531:jasplakinolide; C078290:manzamine A; C529254:majusculamide C