title: Torsades de pointes related to transient marked QT prolongation following successful emergent percutaneous coronary intervention for acute coronary syndrome.
abstract: We report 2 patients in whom transient marked QT prolongation occurred after successful emergent percutaneous coronary intervention (PCI) for acute coronary syndrome. One patient developed torsades de pointes. In both cases, the QT interval became markedly prolonged within 24 hours after PCI, and this prolongation persisted for 4 days. The T waves had a giant and bizarre negative shape with a prolonged T-wave peak to T-wave end interval. No new-onset ischemia or congenital long QT syndrome was related to the episodes. The patients had not taken any drugs that could have prolonged the QT interval, and their serum potassium levels were within normal limits. Torsades de pointes following successful PCI for acute coronary syndrome is uncommon, but acquired long QT syndrome should be considered and treated in patients in whom giant and bizarre negative T waves and QT prolongation develop after PCI.
authors.affiliation: Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan. mihoko_kawabata.cvm@tmd.ac.jp
authors.forename: Mihoko
authors.initials: M
authors.lastname: Kawabata
authors.forename: Kenzo
authors.initials: K
authors.lastname: Hirao
authors.forename: Sasaki
authors.initials: S
authors.lastname: Takeshi
authors.forename: Kaoru
authors.initials: K
authors.lastname: Sakurai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Inagaki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hachiya
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000209:etiology*; D008875:Middle Aged; D018570:Risk Assessment / Q000379:methods; D016171:Torsades de Pointes / Q000175:diagnosis* / Q000209:etiology*