title: Periodontal disease definition may determine the association between periodontitis and pregnancy outcomes.
abstract: OBJECTIVE
  The aim of this secondary analysis is to explore whether the application of different definition criteria of periodontitis, used in other similar studies, has an influence on the significance of the association between periodontitis and prematurity or low birth weight.
  
  
  METHODS
  Fourteen periodontitis definitions and more than 50 periodontal disease continuous measurements, found in 23 published studies, were applied to a cohort study that included 1296 pregnant women. The associations with adverse pregnancy outcomes were analysed using logistic regression analysis.
  
  
  RESULTS
  Six of the 14 tested definitions of periodontitis resulted in statistically significant adjusted odds ratios (ORs) for some of the adverse pregnancy outcomes, while no significance was found for the other eight case definitions. Out of more than 50 periodontal continuous measurements tested, only 17 demonstrated statistically significant ORs.
  
  
  CONCLUSIONS
  Our results support the hypothesis that the significance of the association between periodontal disease and pregnancy outcomes may be determined by the periodontal disease definition or measurement used.
authors.affiliation: Department of Graduate Comprehensive Dentistry, Dental School, University of Barcelona, Barcelona, Spain. cmn49@yahoo.es
authors.forename: Carolina
authors.initials: C
authors.lastname: Manau
authors.forename: Ana
authors.initials: A
authors.lastname: Echeverria
authors.forename: Anna
authors.initials: A
authors.lastname: Agueda
authors.forename: Adrian
authors.initials: A
authors.lastname: Guerrero
authors.forename: Jose J
authors.initials: JJ
authors.lastname: Echeverria
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D016015:Logistic Models; D016017:Odds Ratio; D010518:Periodontitis / Q000145:classification* / Q000150:complications* / Q000175:diagnosis; D011247:Pregnancy; D047928:Premature Birth / Q000209:etiology*; D012307:Risk Factors; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D009626:Terminology as Topic