Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1',2'-5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives.
Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and gram-negative bacterias.
Karnik
A V
AV
Department of Chemistry, University of Mumbai, CST Road, Vidyanagari, Kalina, Mumbai 400098, Maharashtra, India. avkarnik@hotmail.com
Kulkarni
A M
AM
Malviya
N J
NJ
Mourya
B R
BR
Jadhav
B L
BL
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001393:Azoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D050296:Microbial Viability / Q000187:drug effects; D015394:Molecular Structure; D009284:Naphthols / Q000737:chemistry*; D018036:Selenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D001393:Azoles; D009284:Naphthols; D018036:Selenium Compounds