title: Comparison of sensitivity, specificity, positive predictive value, and negative predictive value of stress testing versus 64-multislice coronary computed tomography angiography in predicting obstructive coronary artery disease diagnosed by coronary angiography.
abstract: Sixty-four-multislice coronary computed tomographic angiography (CTA) and coronary angiography were performed in 145 patients (mean age 67 +/- 10 years), and stress testing was performed in 47 of these patients to determine the sensitivity, specificity, positive predictive value, and negative predictive value of coronary CTA and of stress testing in diagnosing obstructive coronary artery disease (CAD) in patients with suspected CAD. In 145 patients, coronary CTA had 98% sensitivity, 74% specificity, 90% positive predictive value, and 94% negative predictive value in diagnosing obstructive CAD. In 47 patients, stress testing had 69% sensitivity, 36% specificity, 78% positive predictive value, and 27% negative predictive value for diagnosing obstructive CAD, whereas coronary CTA had 100% sensitivity, 73% specificity, 92% positive predictive value, and 100% negative predictive value for diagnosing obstructive CAD. In conclusion, coronary CTA has better sensitivity, specificity, positive predictive value, and negative predictive value than stress testing in diagnosing obstructive CAD.
authors.affiliation: Department of Medicine, Cardiology Division, New York Medical College, Valhalla, New York, USA.
authors.forename: Gautham
authors.initials: G
authors.lastname: Ravipati
authors.forename: Wilbert S
authors.initials: WS
authors.lastname: Aronow
authors.forename: Hoang
authors.initials: H
authors.lastname: Lai
authors.forename: John
authors.initials: J
authors.lastname: Shao
authors.forename: Albert J
authors.initials: AJ
authors.lastname: DeLuca
authors.forename: Melvin B
authors.initials: MB
authors.lastname: Weiss
authors.forename: Anthony L
authors.initials: AL
authors.lastname: Pucillo
authors.forename: Kumar
authors.initials: K
authors.lastname: Kalapatapu
authors.forename: Craig E
authors.initials: CE
authors.lastname: Monsen
authors.forename: Robert N
authors.initials: RN
authors.lastname: Belkin
mesh_terms: D000368:Aged; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005080:Exercise Test / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods*