title: [Clinico-pathological study of contralateral lymph node metastasis in pyriform sinus carcinoma].
abstract: OBJECTIVE
  To study the related factors of contralateral lymph node metastasis in pyriform sinus carcinoma.
  
  
  METHODS
  Fifty-three patients with pyriform sinus carcinoma underwent simultaneous neck dissection from Oct. 1993 to Oct. 1999 were collected. Transparent lymph node selection and continuous slicing method were used on the postoperative specimens to observe the status of cervical lymph node metastasis. The relationship between contralateral lymph node metastasis and clinico-pathological factors, ipsilateral neck metastatic status were analyzed by the follow-up data.
  
  
  RESULTS
  Cervical lymph node metastatic rate was 79.2% in 53 patients with pyriform sinus carcinoma. Contralateral cervical lymph node metastatic rate was 35.8%. Contralateral neck metastasis was closely related with clinical N stage, cell differentiation, fused metastasis and extracapsular spread of ipsilateral neck.
  
  
  CONCLUSIONS
  Contralateral neck dissection should be undertaken in patients with N2,3, moderate and low cell differentiation, or fused fused metastasis and extracapsular spread of ipsilateral neck.
authors.affiliation: Department of Otolaryngology, First Affiliated Hospital of China Medical University, Shenyang, 110001, China. guanchao999@hotmail.com
authors.forename: Chao
authors.initials: C
authors.lastname: Guan
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Wenyue
authors.initials: W
authors.lastname: Ji
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D037981:Neck Dissection; D009367:Neoplasm Staging; D012189:Retrospective Studies