title: Signaling to nuclear transport.
abstract: In a recent issue of Molecular Cell, Yoon et al. provide evidence for the control of nucleocytoplasmic transport by protein kinase signaling pathways through phosphorylation of RanBP3, an accessory factor in the Ran GTPase system. This mechanism may coordinate nucleocytoplasmic transport with other mitogenic effects of these pathways.
authors.affiliation: Biomedical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, United Kingdom. p.r.clarke@dundee.ac.uk
authors.forename: Paul R
authors.initials: PR
authors.lastname: Clarke
mesh_terms: D021581:Active Transport, Cell Nucleus / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009687:Nuclear Proteins / Q000378:metabolism; D029543:Nucleocytoplasmic Transport Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D020931:ran GTP-Binding Protein / Q000378:metabolism
chemical_list: D009687:Nuclear Proteins; D029543:Nucleocytoplasmic Transport Proteins; C120587:RAN protein, human; C112820:RANBP3 protein, human; D020931:ran GTP-Binding Protein