title: [Present status and prospects for chemotherapy for advanced or recurrent gastric cancer in our hospital].
abstract: Since S-1 was approved in 1999, the response rate and the disease control rate of the chemotherapy for advanced or recurrent gastric cancer have improved. It is important to perform chemotherapy using key drugs and to plan the chemotherapy for each case. Of the 32 patients in our hospital, the median survival time (MST) was 21 months for chemotherapy in advanced or recurrent gastric cancer during 2003-2006. MST for patients who had up to second- or third-line treatment was longer than for patients with up to first-line treatment. In addition, it there was no difference in prognosis for patients using CPT-11 or taxane at second-line after using S-1 at first-line treatment. The first-line chemotherapy for advanced or recurrent gastric cancer should be decided by the disease condition of each patient and the characteristics of each anti-cancer drug. In addition, the prognosis of patients will improve if second- or third-line chemotherapy can be performed.
authors.affiliation: Dept. of Surgery, Hiroshima Red-Cross Hospital and Atomic Bomb Survivors Hospital, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Ayumi
authors.initials: A
authors.lastname: Matsuyama
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Emi
authors.forename: Shuya
authors.initials: S
authors.lastname: Yano
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Kameyama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Okamoto
authors.forename: Sosei
authors.initials: S
authors.lastname: Kuma
authors.forename: Tohru
authors.initials: T
authors.lastname: Utsunomiya
authors.forename: Teruyoshi
authors.initials: T
authors.lastname: Ishida
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents