[Effects of immunotherapy with infantile recurrent respiratory tract infection by Chinese materia medica].
OBJECTIVE
To explore the effect of Chinese materia medica on immune intervention of infantile recurrent respiratory tract infection.


METHODS
Thirty-one children of recurrent respiratory tract infection were randomly divided into two groups: therapy group was treated with oral Chinese materia medica (b. i. d), control group was only treated with oral carboxymethyl liquor (< 4 years, 3 mL; 4-7 years, 5 mL; > 7 years, 7 mL, t. i. d). The change of IL-12,TNF-alpha, IL-6, IL-13, IL-6 and IL-4 in different time were observed and analyzes.


RESULTS
Compared with the control group, the level of IL-12 and IL-2 was significantly increased after treatment of oral Chinese materia medica (P < 0.01), however, the level of TNF-alpha, IL-13, IL-4, and IL-6 was decreased after treatment (P < 0.01). During one years follow-up study, the frequency of respiratory infection every year of therapy group was significantly decreased than that of control group.


CONCLUSIONS
Chinese materia medica could prevent infantile recurrent respiratory tract infection effectively, increase humoral immunity function and ensure normal growth in children.
Hu
Guo-Hua
GH
Medical College of Jinhua College of Profession & Technology College, Jinhua 321000, China. ghh53021@163.com
Wang
Jing-He
JH
Yao
Jing-Chan
JC
Shi
Xun-Tong
XT
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008419:Materia Medica / Q000627:therapeutic use*; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000628:therapy*
D008419:Materia Medica