title: Bovicin HC5, a lantibiotic produced by Streptococcus bovis HC5, catalyzes the efflux of intracellular potassium but not ATP.
abstract: Bovicin HC5, a broad-spectrum lantibiotic produced by Streptococcus bovis HC5, catalyzed the efflux of intracellular potassium from Streptococcus bovis JB1, a sensitive strain. The level of ATP also decreased, but this decline appeared to be caused by the activity of the F(1)F(0) ATPase rather than efflux per se.
authors.affiliation: Department of Microbiology, Cornell University, Ithaca, New York 14853, USA.
authors.forename: Hilário C
authors.initials: HC
authors.lastname: Mantovani
authors.forename: James B
authors.initials: JB
authors.lastname: Russell
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001430:Bacteriocins / Q000096:biosynthesis / Q000378:metabolism / Q000494:pharmacology*; D003470:Culture Media; D005947:Glucose / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D006180:Proton-Translocating ATPases / Q000378:metabolism; D016985:Streptococcus bovis / Q000145:classification / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D003470:Culture Media; C514465:bovicin HC5, Streptococcus bovis HC5; D000255:Adenosine Triphosphate; D006180:Proton-Translocating ATPases; D005947:Glucose; D011188:Potassium