title: Alexithymia and outcome in psychotherapy.
abstract: BACKGROUND
  About 25% of all patients seeking psychotherapeutic treatment are considered to be alexithymic. Alexithymia has been assumed to be negatively associated with therapeutic outcome. On the other hand, it is unclear to which extent alexithymia itself may be modified by psychotherapeutic interventions.
  
  
  METHODS
  From 414 consecutively admitted inpatients, 297 were followed up after 4 weeks (t1) and after 8-12 weeks (t2) upon discharge. Patients were treated with psychodynamic group therapy in a naturalistic setting. The Toronto Alexithymia Scale (TAS-20) and the Symptom Checklist-90 were administered.
  
  
  RESULTS
  Twenty-seven percent of the patients were alexithymic (TAS-20 >/=61) at baseline. Multivariate models with repeated measurements indicated significant changes in Global Severity Index of the Symptom Checklist-90 in both alexithymic and nonalexithymic subjects. However, alexithymic subjects had significantly higher Global Severity Index scores than nonalexithymic subjects at t0, t1 and t2 (p < 0.001). The TAS-20 scores demonstrated a high relative stability in the total sample. However, in the alexithymic group, the TAS-20 scores changed considerably from baseline to discharge [66.3 (SD = 4.7) to 55.9 (SD = 9.9); t = 8.69; d.f. = 79; p < 0.001].
  
  
  CONCLUSIONS
  The inpatient treatment program including psychodynamic group therapy significantly reduced psychopathological distress and alexithymic features in alexithymic patients. Still, these patients suffered from higher psychopathological distress at discharge than nonalexithymics. Therefore, alexithymic features may negatively affect the long-term outcome.
authors.affiliation: Department of Psychiatry and Psychotherapy, University of Greifswald, Stralsund, Germany.
authors.forename: Hans Joergen
authors.initials: HJ
authors.lastname: Grabe
authors.forename: Jorg
authors.initials: J
authors.lastname: Frommer
authors.forename: Annegret
authors.initials: A
authors.lastname: Ankerhold
authors.forename: Cornelia
authors.initials: C
authors.lastname: Ulrich
authors.forename: Ralf
authors.initials: R
authors.lastname: Groger
authors.forename: Gabriele Helga
authors.initials: GH
authors.lastname: Franke
authors.forename: Sven
authors.initials: S
authors.lastname: Barnow
authors.forename: Harald J
authors.initials: HJ
authors.lastname: Freyberger
authors.forename: Carsten
authors.initials: C
authors.lastname: Spitzer
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D000437:Alcoholism / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D015995:Prevalence; D011615:Psychotherapy, Group / Q000379:methods*; D012720:Severity of Illness Index; D016896:Treatment Outcome