title: Correlation between compression, tensile and tearing tests on healthy and calcified aortic tissues.
abstract: An anastomosis performed in calcified tissues tears up faster than in healthy tissues. This study develops and validates an in vitro non-destructive method to distinguish healthy from calcified aortic tissues. An uniaxial unconfined compression test is able to distinguish healthy from calcified aortas (p<0.01). The compressive E-modulus at a strain level of 10% is 227+/-34kPa for artificially calcified and 147+/-15kPa for healthy porcine aortic tissues. Calcified aortic tissues have a lower tensile strength than healthy porcine aortic tissues (p<0.05). The ultimate tensile strength is 1.34+/-0.18MPa and 1.55+/-0.31MPa for artificially calcified and healthy porcine aortic tissues respectively. Calcified aortic tissues have a lower resistance to tearing than healthy aortic tissues (p<0.05). The resistance to tearing is 1.78+/-0.33N/mm and 2.16+/-0.64N/mm for artificially calcified and healthy porcine aortic tissues respectively.
authors.affiliation: Division of Biomechanics and Engineering Design, Katholieke Universiteit Leuven, Belgium. joris.walraevens@mech.kuleuven.be
authors.forename: Joris
authors.initials: J
authors.lastname: Walraevens
authors.forename: Bert
authors.initials: B
authors.lastname: Willaert
authors.forename: Gunter
authors.initials: G
authors.lastname: De Win
authors.forename: Andrea
authors.initials: A
authors.lastname: Ranftl
authors.forename: Joris
authors.initials: J
authors.lastname: De Schutter
authors.forename: Jos Vander
authors.initials: JV
authors.lastname: Sloten
mesh_terms: D000818:Animals; D001012:Aorta, Abdominal / Q000503:physiopathology*; D002114:Calcinosis / Q000503:physiopathology*; D019245:Compressive Strength; D055119:Elastic Modulus; D004867:Equipment Design; D019544:Equipment Failure Analysis; D066298:In Vitro Techniques; D010812:Physical Stimulation / Q000295:instrumentation*; D013048:Specimen Handling / Q000295:instrumentation*; D013223:Statistics as Topic; D013314:Stress, Mechanical; D013552:Swine; D013718:Tensile Strength; D014159:Transducers