Two new triterpenoid saponins from the carpophore of Xanthoceras sorbifolia Bunge.
Two new triterpenoid saponins (1, 2) and a known sapogenin (3) were isolated from the dried carpophore of Xanthoceras sorbifolia Bunge. (Sapindaceae), and their structures were established as 3-O-beta-d-glucopyranosyl, 28-O-[alpha-l-rhamnosyl (1 --> 2)]-beta-d-glucopyranosyl 16-deoxybarrin-gtogenol C (1), 3-O-[beta-d-glucopyranosyl(1 --> 6)] 3'-angeloyl)-beta-d-glucopyranosyl, 28-O-[alpha-l-rhamnosyl(1 --> 2)]-beta-d-glucopyranosyl 16-deoxybarringtogenol C (2), 16-deoxybarringtogenol C (3), by spectral and chemical methods. Compounds 1 and 2 were found to have activity of inhibiting the proliferation of two human tumour cell lines while compound 3 was inactive.
Li
Wei
W
Research Department of Natural Medicine, Shenyang Pharmaceutical University, Shenyang, China.
Li
Xian
X
Yang
Jia
J
Meng
Da-Li
DL
Li
Ning
N
D002470:Cell Survival / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D013058:Mass Spectrometry; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029631:Sapindaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
D004365:Drugs, Chinese Herbal; D053978:Pentacyclic Triterpenes; D012503:Saponins