Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease.
A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was based on electrocardiography and a cardiac computed tomography confirmed an ascending aortic aneurysm. Coronary angiography showed mural irregularity and a 50% constriction in the first diagonal artery. Following treatment with urokinase, corticosteroids, colchicine, and aspirin, most symptoms gradually improved. There were no complications noted at the one-year follow-up evaluation. Myocardial infarction is a rare event in children with Behçet's disease; treatment with corticosteroids and colchicine can result in regression of concomitant aneurysm.
Zhuang
Jian
J
Department of Pediatric Cardiology, Guangdong Provincial Cardiovascular Institute, Guangzhou, China.
Wang
Shushui
S
Zhang
Zhiwei
Z
Zeng
Shaoying
S
Shi
Yunzhen
Y
Nong
Shaohan
S
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001014:Aortic Aneurysm / Q000175:diagnosis*; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D002648:Child; D003078:Colchicine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D021621:Imaging, Three-Dimensional; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000209:etiology*; D036542:Tomography, Spiral Computed
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003078:Colchicine; D008775:Methylprednisolone