title: Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial.
abstract: OBJECTIVE
  The purpose of this study was to determine whether hypnotic analgesia can reduce the need for intravenous sedation analgesia without increasing pain and anxiety levels during abortion.
  
  
  METHODS
  A cohort of 350 women who were scheduled for surgical abortion (< 14 weeks' gestation) were assigned randomly to a standard care group or a group that received a standardized hypnotic analgesia intervention 20 minutes before and throughout the surgical procedure. Primary outcome was the difference between the 2 groups: (1) the proportion who received sedation (yes/no) during the surgical procedure and (2) self-assessments of pain and anxiety during suction evacuation of uterus content.
  
  
  RESULTS
  Women who underwent hypnosis required less intravenous sedation analgesia (108/172 women; 63%) than the control group (149/175 women; 85%; P < .0001) and self-reported no difference in pain, but not in anxiety, levels during suction evacuation.
  
  
  CONCLUSIONS
  Hypnotic interventions can be effective as an adjunct to pharmacologic management of acute pain during abortion.
authors: Research Center, Hôpital St-François d'Assise, Quebec City, Canada.
authors: Isabelle
authors: I
authors: Marc
authors: Pierre
authors: P
authors: Rainville
authors: Benoît
authors: B
authors: Masse
authors: René
authors: R
authors: Verreault
authors: Lucie
authors: L
authors: Vaillancourt
authors: Estelle
authors: E
authors: Vallée
authors: Sylvie
authors: S
authors: Dodin
mesh_terms: D000028:Abortion, Induced / Q000379:methods*; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000188:drug therapy; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006801:Humans; D006991:Hypnosis, Anesthetic / Q000379:methods*; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D008874:Midazolam / Q000008:administration & dosage; D008875:Middle Aged; D010147:Pain Measurement; D011247:Pregnancy; D011261:Pregnancy Trimester, First
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam; D005283:Fentanyl