Inverted fixation-off sensitivity in atypical benign partial epilepsy.
Fixation-off sensitivity is an electroencephalographic phenomenon characterized by spike-and-wave discharges that only occur when central vision and fixation are eliminated. It is especially seen in children with Panayiotopoulos-type, early-onset, benign childhood occipital epilepsy or Gastaut type, late-onset, childhood occipital epilepsy. It can also be seen in eyelid myoclonia with absences, in other idiopathic generalized epilepsies, and in asymptomatic children without epilepsy. We describe a boy with atypical, benign partial epilepsy of childhood who exhibited the reverse: epileptiform activity that was suppressed by the absence of central vision or fixation, and activated by central vision or fixation.
Nicolai
Joost
J
Department of Neurology, University Hospital Maastricht, Maastricht, The Netherlands. jnic@sneu.azm.nl
Vles
Johan S H
JS
van Tellingen
Vera
V
van Kranen-Mastenbroek
Vivianne H J M
VH
D002648:Child; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000503:physiopathology*; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D008297:Male; D014785:Vision, Ocular / Q000502:physiology*