Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors.
Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiography) registration of mouse tumors. The registration accuracy assessed by calculating the average minimal distance between two skew lines was in the order of 0.2-0.3 mm.
Christian
Nicolas
N
Center for Molecular Imaging and Experimental Radiotherapy, Université Catholique de Louvain, Brussels, Belgium.
Lee
John A
JA
Bol
Anne
A
De Bast
Marc
M
Gallez
Bernard
B
Grégoire
Vincent
V
D000818:Animals; D001345:Autoradiography; D004867:Equipment Design; D005354:Fibrosarcoma / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D007103:Immobilization / Q000295:instrumentation*; D008297:Male; D051379:Mice; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation*; D013848:Thigh; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed