The clinical dilemma--prescribing in pregnancy.
Antipsychotic prescription in pregnancy is a complex topic and raises a great deal of anxiety in professionals. There is limited data about atypical antipsychotic prescription in pregnancy and its possible teratogenicity. There are no randomised controlled studies of atypical antipsychotic use in pregnancy due to obvious reasons of ethical issues. We present two cases where a choice had to be made as to whether to prescribe Olanzapine during pregnancy, with different results.
Ramkisson
Roshelle
R
Bolton, Salford and Trafford Mental Health NHS Trus, England.
Campbell
Margaret
M
Agius
Mark
M
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy*; D002746:Chlorpromazine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006228:Hand Deformities, Congenital / Q000139:chemically induced*; D006801:Humans; D007231:Infant, Newborn; D016651:Lithium Carbonate / Q000009:adverse effects / Q000627:therapeutic use; D000077152:Olanzapine; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D018570:Risk Assessment; D012562:Schizophrenia, Disorganized / Q000188:drug therapy*
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D016651:Lithium Carbonate; D000077152:Olanzapine; D002746:Chlorpromazine