title: Investigating the potential of polymer gel dosimetry for interventional radiology: first results.
abstract: Complex interventional radiology (IR) procedures contribute an increasing percentage of the overall medical radiation exposure of the population making accurate dosimetry a challenge. Magnetic resonance (MR) based polymer gel dosimetry has been widely employed in complex dosimetric problems in radiotherapy. The aim of this note is to investigate the feasibility of normoxic gel dosimetry in IR. Dose response, energy dependence and dose rate dependence were investigated in irradiation set-ups relevant to IR for a particular normoxic gel, based on methacrylic acid (MAA) as the monomer and including tetrakis-hydroxy-methyl-phosphonium chloride (THPC) as antioxidant. The gel presents a linear dose response beyond a 25 cGy threshold. No significant energy dependence was observed in the useful range of interventional radiology (80-110 kVp). A linear correlation between the gel response and dose rate was observed in the range of dose rates relevant to IR (5-8 cGy min(-1)). These results demonstrate a reduction of gel sensitivity at very low dose rate levels. A possible explanation of this effect is suggested.
authors: School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece. pantonio@med.duth.gr
authors: P E
authors: PE
authors: Antoniou
authors: P
authors: P
authors: Bousbouras
authors: R
authors: R
authors: Sandaltzopoulos
authors: E
authors: E
authors: Kaldoudi
mesh_terms: D004307:Dose-Response Relationship, Radiation; D004867:Equipment Design; D005609:Free Radicals; D005782:Gels / Q000737:chemistry*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008689:Methacrylates / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D015642:Radiology, Interventional / Q000295:instrumentation* / Q000379:methods; D011874:Radiometry; D011878:Radiotherapy / Q000295:instrumentation*
chemical_list: D005609:Free Radicals; D005782:Gels; D008689:Methacrylates; D009943:Organophosphorus Compounds; D011108:Polymers; C014850:tetramethylolphosphonium chloride; C008384:methacrylic acid; D010100:Oxygen