title: The influence of curvature on membrane domains.
abstract: An interdependence between local curvature and domain formation has been observed in both cell and model membranes. An implication of this observation is that domain formation in model membranes may be modulated by membrane curvature. In this paper, small-angle neutron scattering (SANS) is used to examine the influence of membrane curvature (i.e., vesicle size) on the formation of membrane domains. It is found that, although vesicle size and polydispersity are not significantly altered by the formation of membrane domains, the area fraction occupied by domains depends on the overall vesicle size. In particular, increasing membrane curvature (i.e., decreasing vesicle size) results in increased area fractions of membrane domains.
authors: National Research Council, Canadian Neutron Beam Centre, Chalk River Laboratories, Chalk River, ON K0J1J0, Canada.
authors: Jeremy
authors: J
authors: Pencer
authors: Andrew
authors: A
authors: Jackson
authors: Norbert
authors: N
authors: Kucerka
authors: Mu-Ping
authors: MP
authors: Nieh
authors: John
authors: J
authors: Katsaras
mesh_terms: D002462:Cell Membrane / Q000737:chemistry*; D045424:Complex Mixtures / Q000737:chemistry; D008563:Membrane Lipids / Q000737:chemistry; D008567:Membranes, Artificial; D033363:Neutron Diffraction; D053838:Scattering, Small Angle; D013696:Temperature; D053835:Unilamellar Liposomes / Q000737:chemistry
chemical_list: D045424:Complex Mixtures; D008563:Membrane Lipids; D008567:Membranes, Artificial; D053835:Unilamellar Liposomes