title: Reduction of infracardiac intestinal activity by a small amount of soda water in technetium-99m tetrofosmin myocardial perfusion scintigraphy with adenosine stress.
abstract: BACKGROUND
  In technetium (Tc)-99m myocardial perfusion imaging (MPI), intestinal activity often interferes with the assessment of myocardial perfusion of the inferior wall. We examined whether a small amount of soda water prevents intestinal activity and improves image quality of the inferior wall in Tc-99m tetrofosmin MPI.
  
  
  RESULTS
  Ninety-five patients referred for 1-day rest/stress Tc-99m tetrofosmin MPI were assigned to one of two groups automatically, according to the date when they underwent MPI: the soda water group (n = 63) ingested 100 mL soda water just before image acquisition after adenosine stress, and the control group (n = 32) underwent no intervention. The frequency of intestinal activity was assessed visually on planar images. The inferior myocardial wall and the abdominal activity adjacent to the myocardium were assessed quantitatively on three different planar images during stress, and the mean inferior wall-to-abdomen (I/A) count ratio was calculated. The frequency of intestinal activity was 69.8% in the soda water group, and 90.6% in the control group (P = .038). The I/A count ratio was significantly higher in the soda water group than in the control group (1.98 +/- 0.51 vs 1.50 +/- 0.35, respectively, P < .0001, +/- SD).
  
  
  CONCLUSIONS
  The intake of 100 mL of soda water improves intestinal activity and improves the image quality of the inferior wall.
authors: Department of Cardiology, Otsu Red Cross Hospital, Otsu City, Shiga, Japan. har@otsu.jrc.or.jp
authors: Masatake
authors: M
authors: Hara
authors: Hajime
authors: H
authors: Monzen
authors: Rie
authors: R
authors: Futai
authors: Koichi
authors: K
authors: Inagaki
authors: Hisashi
authors: H
authors: Shimoyama
authors: Masaru
authors: M
authors: Morikawa
authors: Nobuyoshi
authors: N
authors: Tomioka
authors: Takashi
authors: T
authors: Konishi
authors: Yutaka
authors: Y
authors: Watanabe
authors: Rumio
authors: R
authors: Yuki
authors: Hisato
authors: H
authors: Kobayashi
authors: Kunihiko
authors: K
authors: Hirose
mesh_terms: D000241:Adenosine / Q000008:administration & dosage; D000368:Aged; D016477:Artifacts; D002253:Carbonated Beverages; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000000981:diagnostic imaging* / Q000187:drug effects; D008297:Male; D009943:Organophosphorus Compounds / Q000493:pharmacokinetics*; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000378:metabolism*
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D000241:Adenosine