title: OpenMS - an open-source software framework for mass spectrometry.
abstract: BACKGROUND
  Mass spectrometry is an essential analytical technique for high-throughput analysis in proteomics and metabolomics. The development of new separation techniques, precise mass analyzers and experimental protocols is a very active field of research. This leads to more complex experimental setups yielding ever increasing amounts of data. Consequently, analysis of the data is currently often the bottleneck for experimental studies. Although software tools for many data analysis tasks are available today, they are often hard to combine with each other or not flexible enough to allow for rapid prototyping of a new analysis workflow.
  
  
  RESULTS
  We present OpenMS, a software framework for rapid application development in mass spectrometry. OpenMS has been designed to be portable, easy-to-use and robust while offering a rich functionality ranging from basic data structures to sophisticated algorithms for data analysis. This has already been demonstrated in several studies.
  
  
  CONCLUSIONS
  OpenMS is available under the Lesser GNU Public License (LGPL) from the project website at http://www.openms.de.
authors: Center for Bioinformatics, Eberhard Karls University Tübingen, Sand 14, 72076 Tübingen, Germany. sturm@informatik.uni-tuebingen.de
authors: Marc
authors: M
authors: Sturm
authors: Andreas
authors: A
authors: Bertsch
authors: Clemens
authors: C
authors: Gröpl
authors: Andreas
authors: A
authors: Hildebrandt
authors: Rene
authors: R
authors: Hussong
authors: Eva
authors: E
authors: Lange
authors: Nico
authors: N
authors: Pfeifer
authors: Ole
authors: O
authors: Schulz-Trieglaff
authors: Alexandra
authors: A
authors: Zerck
authors: Knut
authors: K
authors: Reinert
authors: Oliver
authors: O
authors: Kohlbacher
mesh_terms: D000465:Algorithms; D013058:Mass Spectrometry / Q000379:methods*; D011381:Programming Languages; D012984:Software