title: Relations between open-field, elevated plus-maze, and emergence tests as displayed by C57/BL6J and BALB/c mice.
abstract: The relations between open-field, elevated plus-maze, and emergence tests were examined in two strains of mice. In the open-field, C57BL/6J mice had more ambulatory movements and rears but not stereotyped movements relative to BALB/c. In addition, C57BL/6J mice entered more often than BALB/c into enclosed and open arms of the elevated plus-maze. When placed inside a large enclosure, C57BL/6J mice emerged more quickly than BALB/c from a small toy object. In the entire series of mice, ambulation and rears in the open-field were linearly correlated with open and enclosed arm visits in the elevated plus-maze. Ambulatory movements and rears were also correlated with emergence latencies. In contrast, stereotyped movements were correlated with emergence latencies, but not with any elevated plus-maze value. These results specify the extent and limits of association between the three tests.
authors: Université de Rouen, Faculté de Sciences, Centre Hospitalier de l'Université de Montréal/St-Luc, Unité de Recherche en Sciences Neurologiques, Montréal, Québec, Canada H2X 3J4. robert.lalonde@umontreal.ca
authors: R
authors: R
authors: Lalonde
authors: C
authors: C
authors: Strazielle
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology; D005106:Exploratory Behavior / Q000502:physiology*; D005260:Female; D008297:Male; D018782:Maze Learning / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C / Q000502:physiology*; D008810:Mice, Inbred C57BL / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D013045:Species Specificity