title: Estimation and characterisation of budesonide tablets impurities.
abstract: Budesonide is the 16alpha,17alpha-acetal of 16alpha-hydroxyprednisolone with n-butyraldehyde, endowed with anti-inflammatory activity. In a sample of budesonide tablets, kept for 3 years at 25 degrees C and 60% RH unknown impurities, not reported in European Pharmacopoiea, were present. Their identification was achieved by means of chemical and spectroscopic methods.
authors: Dipartimento di Chimica, Biochimica e Biotecnologie per la Medicina, Università di Milano-Via Saldini, 50-20133 Milano, Italy. patrizia.ferraboschi@unimi.it
authors: Patrizia
authors: P
authors: Ferraboschi
authors: Vittorio
authors: V
authors: Bertacche
authors: Isabella
authors: I
authors: Maccone
authors: Elena
authors: E
authors: Pini
authors: Laura
authors: L
authors: Ragonesi
authors: Alessio
authors: A
authors: Venturini
authors: Riccardo
authors: R
authors: Stradi
mesh_terms: D019819:Budesonide / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004340:Drug Contamination; D013607:Tablets
chemical_list: D013607:Tablets; D019819:Budesonide