title: Age and interstimulus interval in forward and backward long-trace taste-aversion conditioning.
abstract: Rats, 70-79 days old and 477-557 days old, experienced either a forward or backward taste-aversion conditioning trial with a 15-min. or 45-min. interstimulus interval. Forward conditioning was evident in both age groups at both interstimulus intervals. Backward conditioning was evident in both age groups only at the 15-min. interstimulus interval. The failure to obtain backward conditioning at the 45-min. interval was attributed to the effect of stress, produced by injection of the US, on long-trace conditioning. As reported with forward conditioning, stress may alter metabolic rate such that the intervals at which associations can be formed are shortened.
authors: Susquehanna University, USA.
authors: Eli
authors: E
authors: Minnier
authors: James R
authors: JR
authors: Misanin
authors: Charles F
authors: CF
authors: Hinderliter
mesh_terms: D000367:Age Factors; D000375:Aging / Q000502:physiology; D000704:Analysis of Variance; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology*; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology*; D004326:Drinking / Q000187:drug effects / Q000502:physiology*; D005260:Female; D007274:Injections, Intraperitoneal; D018021:Lithium Chloride / Q000494:pharmacology; D051381:Rats; D012055:Reinforcement Schedule; D012439:Saccharin; D013649:Taste / Q000187:drug effects / Q000502:physiology*
chemical_list: D012439:Saccharin; D018021:Lithium Chloride