The role of lipotropins as hematopoietic factors and their potential therapeutic use.
Lipotropins are peptides that act as hormones that are released from a common precursor together with other physiologically important peptides; their function is to mobilize the lipids that are stored in adipocytes as an energy reserve. This review will explain the existing scientific evidence on the action of lipotropins in adipocytes and, specifically, when these lipotropins activate bone marrow adipocytes to function as hematopoietic factors and suggest the potential therapeutic use of lipotropins based on these effects.
Halabe Bucay
Alberto
A
Department of Pediatrics, Hospital Angeles Lomas, Huixquilucan, Mexico. doctorhalabe@hotmail.com
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D017667:Adipocytes / Q000166:cytology / Q000502:physiology; D001854:Bone Marrow Cells / Q000166:cytology / Q000502:physiology; D006402:Hematologic Diseases / Q000188:drug therapy*; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D007239:Infections / Q000188:drug therapy; D008083:beta-Lipotropin / Q000502:physiology* / Q000627:therapeutic use*
D008083:beta-Lipotropin