[Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement].
Sarcoidosis is a multisystemic disease which diagnosis depends on the presence of nonnecrotizing granulomas in the biopsy. However there are variants such as necrotizing sarcoidal granulomas or nodular sarcoidosis which have atypical findings and make difficult the differential diagnosis with other infectious processes. We describe a case of a man who develops granulomas with extensive necrosis in a systemic sarcoidosis that affected the lung and the central nervous system. This finding made us to make the diagnosis of tuberculosis and delay the specific treatment.
Ríos Fernández
R
R
Unidad de Enfermedades Sistémicas, Nuerología, Anatomía Patológica, Hospital Clínico San Cecilio, Granada. rriosfer@hotmail.com
Callejas-Rubio
J L
JL
Guerrero Fernández
M
M
Serrano Falcón
M M
MM
Ortego-Centeno
N
N
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003072:Cognition Disorders / Q000209:etiology; D003951:Diagnostic Errors; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009336:Necrosis; D011241:Prednisone / Q000627:therapeutic use; D012074:Remission Induction; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis; D014549:Urinary Incontinence / Q000209:etiology; D014717:Vertigo / Q000209:etiology
D000995:Antitubercular Agents; D011241:Prednisone; D008727:Methotrexate