Leiomyosarcoma originating from the superior mesenteric vein: a case report and review of the literature.
We describe a rare case of leiomyosarcoma originating from the superior mesenteric vein with concomitant liver metastases in a 62-year-old woman. She underwent a tumor resection and venous reconstruction, right hemicolectomy, and right hepatic lobectomy. Since the tumor was weakly positive for c-kit, she was treated with imatinib mesylate for the recurrent liver tumors. She has survived for about 3 years after undergoing the surgical procedures.
Kuma
Sosei
S
Department of Surgery, Hiroshima Red Cross Hospital, Hiroshima 730-8619, Japan. kumasosei@yahoo.co.jp
Utsunomiya
Tohru
T
Yano
Shuya
S
Kameyama
Toshifumi
T
Okamoto
Masahiro
M
Matsuyama
Ayumi
A
Hashimoto
Kohji
K
Yamamoto
Manabu
M
Ezaki
Takahiro
T
Fujihara
Megumu
M
Ishida
Teruyoshi
T
D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D001549:Benzamides; D017024:Chemotherapy, Adjuvant; D003082:Colectomy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D000068877:Imatinib Mesylate; D007890:Leiomyosarcoma / Q000201:enzymology / Q000556:secondary* / Q000628:therapy; D008113:Liver Neoplasms / Q000737:chemistry / Q000201:enzymology / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008642:Mesenteric Veins / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis; D011743:Pyrimidines / Q000627:therapeutic use; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000628:therapy; D014656:Vascular Surgical Procedures
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D019009:Proto-Oncogene Proteins c-kit