Complex sesquiterpenoids with tyrosinase inhibitory activity from the leaves of Chloranthus tianmushanensis.
Investigation of the leaves of Chloranthus tianmushanensis resulted in the isolation and characterization of two new sesquiterpene dimers with a rare 18-membered triester ring, tianmushanol (1) and 8-O-methyltianmushanol (2), and four known sesquiterpenes. Their structures were established by spectroscopic means. The inhibitory activities against tyrosinase of all isolates were also evaluated.
Wu
Bin
B
Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, PR China.
Chen
Jun
J
Qu
Haibin
H
Cheng
Yiyu
Y
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
C530237:8-O-methyltianmushanol; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; C530236:tianmushanol; D014442:Monophenol Monooxygenase