title: Albumin and immunoglobulin depletion of human plasma.
abstract: Plasma and serum have been the focus of intense study in recent years in the expectation that they will provide important biomarkers of health and disease, without the need for invasive procedures. This aim has been hindered by the fact that a few highly abundant proteins dominate the protein profile, masking the lower abundance proteins and limiting our ability to analyse the entire plasma proteome. This chapter details a simple and effective method for removal of two of the most dominant proteins in plasma, albumin and immunoglobulin.
authors: University of Liverpool, Liverpool, Great Britain.
authors: Rosalind E
authors: RE
authors: Jenkins
authors: Neil R
authors: NR
authors: Kitteringham
authors: Carrie
authors: C
authors: Greenough
authors: B Kevin
authors: BK
authors: Park
mesh_terms: D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D012709:Serum Albumin / Q000302:isolation & purification*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D007136:Immunoglobulins; D012709:Serum Albumin