title: A selective approach to restorative proctocolectomy without ileostomy: a single centre experience.
abstract: OBJECTIVE
  A single surgeon series on complications and functional outcomes following restorative proctocolectomy (RPC) is presented.
  
  
  METHODS
  An ethically-approved database was used to collect data on all patients undergoing RPC at a single institution. Patient demographics, operative details, complications and functional outcomes were assessed. The impact of ileostomy omission on outcomes was also assessed.
  
  
  RESULTS
  Two hundred patients undergoing RPC between 1987 and 2006 were included. There were 122 (61.0%) males and the mean age at surgery was 37.6 years. A J pouch was constructed in 199 (99.5%) patients and an ileostomy omitted in 160 (80.0%). Since adopting a selective policy after the 36th consecutive patient in the series, only 9 (5.5%) patients have had an ileostomy constructed at the time of pouch construction. Complications occurred in 112 (56.3%) patients, with anastomotic stricture (20.6%) and pouchitis (28.6%) being the most common. Anastomotic stricture was more common in those patients receiving an ileostomy (43.6%vs 15.0%, P < 0.001), as were pouch-cutaneous fistulae (5.1%vs 0.6%, P = 0.039) and pelvic sepsis (15.4%vs 5.0%, P = 0.023). Functional outcomes were good, with median 24-h stool frequency of five motions at 1 year. There was increased urgency to defaecate which in part may be due to a significant decline in the use of antidiarrhoeal medication during follow up.
  
  
  CONCLUSIONS
  Selective omission of a covering ileostomy in most cases can produce good results following RPC with no increase in the risk of septic complications or pouch failure, and a decreased risk of anastomotic stricture, with maintenance of good function in the majority.
authors: Department of Biosurgery and Surgical Technology, Imperial College London, London, UK.
authors: R E
authors: RE
authors: Lovegrove
authors: P
authors: P
authors: Symeonides
authors: P P
authors: PP
authors: Tekkis
authors: P B
authors: PB
authors: Goodfellow
authors: A J
authors: AJ
authors: Shorthouse
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000601:surgery; D000328:Adult; D000714:Anastomosis, Surgical; D003093:Colitis, Ulcerative / Q000601:surgery; D005260:Female; D006801:Humans; D007081:Ileostomy; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods*; D020127:Recovery of Function; D016879:Salvage Therapy; D012725:Sexual Behavior / Q000706:statistics & numerical data; D016896:Treatment Outcome