Advances in experimental and translational research in the treatment of hepatocellular carcinoma.
Hepatocellular cancer (HCC) is the fifth-leading cause of cancer and the third-leading cause of cancer related deaths world-wide. Current treatment options are limited, as HCC has been shown to be a highly resistant type of cancer to most current treatment modalities. Novel approaches are being explored in the fields of gene therapy, viral oncolytics, radioembolization, and several new biologic therapies. This article summarizes these recent clinical findings and discusses what role they will have in the future treatment of HCC.
Kidner
Travis
T
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Dai
Menghua
M
Adusumilli
Prasad S
PS
Fong
Yuman
Y
D001691:Biological Therapy / Q000379:methods*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy*; D019317:Evidence-Based Medicine; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy*; D050130:Oncolytic Virotherapy / Q000379:methods; D012307:Risk Factors