title: Tobacco use is a risk factor for mesh erosion after abdominal sacral colpoperineopexy.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the association between smoking and vaginal mesh erosion after abdominal sacral colpoperineopexy with the use of type 1 polypropylene mesh.
  
  
  METHODS
  All cases of mesh erosion (n = 27) that were diagnosed between October 2003 and June 2006 were identified and compared with matched control cases (n = 81). Control cases were matched for age, diabetes mellitus status, hypoestrogenic state (menopausal status, chronic steroid use, use of hormone therapy), abdominal-vaginal rectocele repair, culdoplasty, and concomitant hysterectomy. Demographic data, surgical characteristics, and postoperative complications were also compared between groups. Continuous data were compared using 2-sample Student t tests. Categoric data were compared with the use of Pearson Chi-square tests.
  
  
  RESULTS
  The odds of experiencing mesh erosion was significantly greater in smokers than in nonsmokers (odds ratio, 4.4; 95% CI, 1.3, 14.4; P = .010) when potential confounders were similar between groups.
  
  
  CONCLUSIONS
  Tobacco use is a risk factor for vaginal mesh erosion after abdominal sacral colpoperineopexy with the use of type 1 polypropylene mesh.
authors: Division of Female Pelvic Medicine and Reconstructive Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. jklowman@iupui.edu
authors: Joye K
authors: JK
authors: Lowman
authors: Patrick J
authors: PJ
authors: Woodman
authors: Patrick A
authors: PA
authors: Nosti
authors: Richard C
authors: RC
authors: Bump
authors: Colin L
authors: CL
authors: Terry
authors: Douglass S
authors: DS
authors: Hale
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D015986:Confounding Factors, Epidemiologic; D004868:Equipment Failure; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008022:Ligaments / Q000601:surgery; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology; D019736:Prostheses and Implants / Q000009:adverse effects*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D013526:Surgical Mesh / Q000009:adverse effects*; D013536:Suture Techniques; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000601:surgery*