title: Paraneoplastic hyperinsulinism and secondary hypoglycaemia in a patient with advanced colon cancer: a rare association.
abstract: We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanced cancer, the diagnosis, and possible treatments of this rare paraneoplastic endocrine complication.
authors: Medical Oncology Unit, University Hospital La Fe, Avenida Campanar 19-21, Valencia 46009, Spain. rdiazbev@hotmail.com
authors: Roberto
authors: R
authors: Díaz
authors: Jorge
authors: J
authors: Aparicio
authors: Andrea
authors: A
authors: Mendizábal
authors: Marisa
authors: M
authors: Faus
authors: Tania
authors: T
authors: Fleitas
authors: Francisco
authors: F
authors: Aparisi
authors: Maria
authors: M
authors: Martín
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D015897:Comorbidity; D017809:Fatal Outcome; D006801:Humans; D006946:Hyperinsulinism / Q000175:diagnosis / Q000503:physiopathology; D007003:Hypoglycemia / Q000209:etiology* / Q000503:physiopathology; D008297:Male