[Analysis of 993 cases of fetal malformations from 1999 to 2006].
OBJECTIVE
To study the value of prenatal ultrasound in the diagnosis of fetal malformations.


METHODS
We retrospectively analyzed the clinical data of 993 cases of neonates and induced babies with malformations who were labored in our hospital from January 1999 to October 2006.


RESULTS
The incidence rate of fetal malformation was 22.5 per thousand in our study group. The detection rate of prenatal ultrasound was 79.02% (1 062/1 344), among which the detection rate of the severe malformations (87.58%, 860/982) were significantly higher than that of the minor malformations (55.80%, 202/362) (P < 0.005). The false negative rate was high for the extremity malformations (39.46%) and facial malformations (31.91%), especially the acrosclerodermas, simple cleft palates, and ear deformities.


CONCLUSIONS
Prenatal ultrasound is sensitive for fetal severe malformations, while the detection rate is low for fetal minor malformations.
Li
Sheng-Li
SL
Department of Ultrasound, Affiliated Shenzhen Maternity and Child Healthcare Hospital, Nanfang Medical University, Shenzhen, Guangdong 518028, China. lishengli63@126.com
Chen
Xiu-Lan
XL
Ouyang
Shu-Yuan
SY
Yao
Yuan
Y
Gong
Bo
B
Chen
Cong-Ying
CY
Yang
Xiao-Dong
XD
Xiao
Zhi-Lian
ZL
Liao
Yu-Mei
YM
D000013:Congenital Abnormalities / Q000000981:diagnostic imaging*; D005188:False Negative Reactions; D006801:Humans; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal