title: Efficient gene transfection with functionalised multicalixarenes.
abstract: Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.
authors: School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK.
authors: Ruth
authors: R
authors: Lalor
authors: Jessica L
authors: JL
authors: DiGesso
authors: Anja
authors: A
authors: Mueller
authors: Susan E
authors: SE
authors: Matthews
mesh_terms: D000588:Amines / Q000737:chemistry; D000818:Animals; D016466:CHO Cells; D047250:Calixarenes / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D050091:Dendrimers; D004591:Electrophoresis, Polyacrylamide Gel; D049452:Green Fluorescent Proteins / Q000235:genetics; D006801:Humans; D007202:Indicators and Reagents; D009000:Monocytes / Q000378:metabolism; D010957:Plasmids / Q000235:genetics; D014162:Transfection / Q000379:methods*
chemical_list: D000588:Amines; D050091:Dendrimers; D007202:Indicators and Reagents; D047250:Calixarenes; D049452:Green Fluorescent Proteins; D004247:DNA