title: Multiresidue analysis of atrazine, diuron and their degradation products in sewage sludge by liquid chromatography tandem mass spectrometry.
abstract: A multiresidue method has been developed to analyze atrazine (ATZ), diuron (DIU), and their major degradation products, desethylatrazine (DEA), desisopropylatrazine (DIA), and dichlorophenylmethylurea in sewage sludge. Liquid chromatography coupled to electrospray tandem mass spectrometry (LC-ESI-MS-MS) allowed, in the multiple-reaction monitoring mode, the simultaneous analysis of these pesticides in only one run after their extraction with ethyl acetate-dichloromethane 90:10 (v/v) and a cleanup on a Florisil column. Stable isotopically labeled ATZ and DIU were used as internal standards to overcome matrix effects during the pesticide quantification. Using fortified samples, the method gave rise to 86-115% as mean recovery values depending on the analyte. Limits of detection (LODs) and of quantification (LOQs) ranging from 0.3 (DIA) to 1.5 (DEA) microg kg(-1) dw and from 0.4 (DIA) to 2.0 (DEA) microg kg(-1) dw, respectively, were sufficient to achieve the monitoring of these molecules in sludge from wastewater treatment plants of the Ile-de-France region.
authors: INRA, UR258 Phytopharmacie et Médiateurs Chimiques, Route de Saint-Cyr, 78026, Versailles Cedex, France.
authors: Aline
authors: A
authors: Ghanem
authors: Philippe
authors: P
authors: Bados
authors: François
authors: F
authors: Perreau
authors: Rachid
authors: R
authors: Benabdallah
authors: Cécile
authors: C
authors: Plagellat
authors: Luiz Felippe
authors: LF
authors: de Alencastro
authors: Jacques
authors: J
authors: Einhorn
mesh_terms: D001280:Atrazine / Q000032:analysis* / Q000378:metabolism; D002138:Calibration; D002853:Chromatography, Liquid; D004237:Diuron / Q000032:analysis* / Q000378:metabolism; D004784:Environmental Monitoring; D015394:Molecular Structure; D010573:Pesticide Residues / Q000032:analysis*; D012722:Sewage / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
chemical_list: D010573:Pesticide Residues; D012722:Sewage; D004237:Diuron; D001280:Atrazine