title: Temporal lobe neoplasm and seizures: how deep does the story go?
abstract: [March 2008-Cleveland Case Report]. There is a well-described association between the occurrence of developmental tumors and the presence of cortical dysplasia in the neighboring brain tissue. The main surgical approaches in the treatment of medically refractory epilepsy related to such developmental tumors include a lesionectomy versus a tailored cortical resection, often guided by an invasive evaluation. This case report describes the surgical management of a 26-year-old female with olfactory auras evolving into automotor seizures and convulsions, occurring in the context of a right temporo-parietal developmental lesion. It illustrates the pros and cons of various surgical approaches, and discusses some pathophysiological aspects of developmental tumors, dysplasia and epilepsy. [Published with video sequences].
authors: Epilepsy Center, Cleveland Clinic Foundation, Ohio 44195, USA. jehil@ccf.org
authors: Lara E
authors: LE
authors: Jehi
authors: Hans O
authors: HO
authors: Lüders
authors: Richard
authors: R
authors: Naugle
authors: Paul
authors: P
authors: Ruggieri
authors: Harold
authors: H
authors: Morris
authors: Nancy
authors: N
authors: Foldvary
authors: Elaine
authors: E
authors: Wyllie
authors: Prakash
authors: P
authors: Kotagal
authors: Bill
authors: B
authors: Bingaman
authors: Dudley
authors: D
authors: Dinner
authors: Richard
authors: R
authors: Prayson
authors: Beate
authors: B
authors: Diehl
authors: Andreas
authors: A
authors: Alexopoulos
authors: Jocelyn
authors: J
authors: Bautista
authors: Robyn
authors: R
authors: Busch
mesh_terms: D000328:Adult; D000654:Amobarbital; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D004292:Dominance, Cerebral; D004833:Epilepsy, Temporal Lobe / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures; D012640:Seizures / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D013702:Temporal Lobe / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives; D000654:Amobarbital