Long-term disease-free survival after hormonal therapy of a patient with recurrent low grade endometrial stromal sarcoma: a case report.
BACKGROUND
Approximately 50% of patients with low-grade endometrial stromal sarcoma (ESS) develop recurrent disease including mainly metastases of pelvis and lung. A solitary pulmonary metastasis of this disease is a rare phenomenon.


METHODS
After initial surgical treatment in 1990, a 28-year-old female developed solitary metastases of the lung in 1998 and 1999, which were surgically removed both times. The patient was then treated with goserelin for 2 years followed by anastrozole to date. She has since been disease-free.


CONCLUSIONS
This case report emphasizes the importance of long-term follow-up and initial surgical treatment of low-grade ESS and suggests systemic hormonal therapy in case of recurrence.
Alkasi
Ozkan
O
Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein-Campus Kiel, Michaelisstrasse 16, 24105, Kiel, Germany. oezkanalkasi@web.de
Meinhold-Heerlein
Ivo
I
Zaki
Rania
R
Fasching
Peter
P
Maass
Nicolai
N
Jonat
Walter
W
Beckmann
Matthias W
MW
D000328:Adult; D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D017273:Goserelin / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000473:pathology; D009570:Nitriles / Q000627:therapeutic use; D018203:Sarcoma, Endometrial Stromal / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D014230:Triazoles / Q000627:therapeutic use
D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014230:Triazoles; D017273:Goserelin; D000077384:Anastrozole