A DNAzyme cascade for the amplified detection of Pb(2+) ions or L-histidine.
DNAzyme cascades activated by Pb(2+)- or L-histidine-dependent DNAzymes yield the horseradish peroxidase-mimicking catalytic nucleic acids that enable the colorimetric or chemiluminescence detection of Pb(2+) or L-histidine.
Elbaz
Johann
J
Institute of Chemistry, Farkas Center for Light-Induced Processes, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Shlyahovsky
Bella
B
Willner
Itamar
I
D002384:Catalysis; D003124:Colorimetry; D021881:DNA, Catalytic / Q000737:chemistry*; D004789:Enzyme Activation; D006639:Histidine / Q000032:analysis*; D006735:Horseradish Peroxidase / Q000737:chemistry; D007477:Ions / Q000032:analysis; D007854:Lead / Q000032:analysis*; D008163:Luminescent Measurements; D009696:Nucleic Acids / Q000737:chemistry; D012680:Sensitivity and Specificity; D013997:Time Factors
D021881:DNA, Catalytic; D007477:Ions; D009696:Nucleic Acids; D007854:Lead; D006639:Histidine; D006735:Horseradish Peroxidase