title: A novel method for comparing 3D target volume delineations in radiotherapy.
abstract: When comparing delineations it is often useful to obtain a local measure of distance between the volume surfaces. Commonly used methods for analysing local distance exhibit fundamental drawbacks which may cause overestimation of the distance or lead to asymmetry in the measure. This paper describes a new method that aims to solve these problems. The new method finds corresponding points between two delineations by traversing a vector field based on the combined gradient of the distance transforms. The proposed method provides a fundamentally more reliable, symmetric measure of distance. This is supported by an illustrative example of observer variation in prostate delineation. An implementation of the method is available on request to the author.
authors: Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. r.w.vanderput@umcutrecht.nl
authors: R W
authors: RW
authors: van der Put
authors: B W
authors: BW
authors: Raaymakers
authors: E M
authors: EM
authors: Kerkhof
authors: M
authors: M
authors: van Vulpen
authors: J J W
authors: JJ
authors: Lagendijk
mesh_terms: D000465:Algorithms; D003952:Diagnostic Imaging / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D015233:Models, Statistical; D016011:Normal Distribution; D011467:Prostate / Q000033:anatomy & histology / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D018787:Radiation Oncology / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D011878:Radiotherapy / Q000379:methods*; D015203:Reproducibility of Results