[Early response to treatment with Glivec detected with 18F-FDG PET in a patient with gastrointestinal stromal tumor].
We present the case of a male patient with gastrointestinal stromal tumor (GIST) in whom we conducted two (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) studies, the first one prior to beginning the treatment with Glivec and the second after one month of treatment. The first (18)F-FDG PET scan detected multiple FDG avid foci in distal esophagus, liver and in an interaortocava lymph node. The second (18)F-FDG PET showed very good response to therapy, with an almost complete disease remission. After 23 months of follow-up, the early response to treatment detected by (18)F-FDG PET was confirmed. The utility of (18)F-FDG PET in the evaluation of response to treatment in GIST is discussed and compared with CT.
Delgado Bolton
R C
RC
Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, España. rbolton@telefonica.net
Ortega Candil
A
A
Pérez Castejón
M J
MJ
Garcerant
M
M
Cabrera Martín
M N
MN
Lapeña Gutiérrez
L
L
Carreras Delgado
J L
JL
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001549:Benzamides; D019788:Fluorodeoxyglucose F18; D046152:Gastrointestinal Stromal Tumors / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006801:Humans; D000068877:Imatinib Mesylate; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D049268:Positron-Emission Tomography; D011743:Pyrimidines / Q000627:therapeutic use*; D019275:Radiopharmaceuticals; D013997:Time Factors
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D000068877:Imatinib Mesylate