title: Effect of multiorgan donation after cardiac death retrieval on lung performance.
abstract: OBJECTIVE
  For donation after cardiac death (DCD) transplantation to achieve its full potential, multiorgan retrieval is desirable. Although there are several novel individual techniques recently described for DCD lung donation, they have not been evaluated or compared in a DCD multiorgan scenario.
  
  
  METHODS
  This study describes (i) the technical aspects and (ii) early lung and abdominal organ performance of several combinations of DCD donor liver, kidney and lung retrieval techniques that would mimic common DCD clinical scenarios.
  
  
  RESULTS
  Lung oxygenation, urine production, bile production and biochemical measures were assessed as the outcome of a complex ex vivo lung, liver and kidney perfusion DCD model.
  
  
  CONCLUSIONS
  Successful ex vivo multiorgan perfusion was possible following the three retrieval techniques tested, with excellent oxygenation over a 2-h assessment period, identical to prior studies where the lungs were tested alone. Multiorgan DCD retrieval, including lungs of good quality, is possible from a variety of clinical scenarios and should therefore be considered with all DCD retrieval opportunities.
authors: Lung Transplant Service, Alfred Hospital and Monash University, Melbourne, Victoria, Australia. g.snell@alfred.org.au
authors: Gregory I
authors: GI
authors: Snell
authors: Bronwyn
authors: B
authors: Levvey
authors: Takahiro
authors: T
authors: Oto
authors: Robin
authors: R
authors: McEgan
authors: Mark
authors: M
authors: Mennan
authors: Leif
authors: L
authors: Eriksson
authors: Trevor
authors: T
authors: Williams
authors: Franklin
authors: F
authors: Rosenfeldt
mesh_terms: D000818:Animals; D003643:Death; D004285:Dogs; D005240:Feasibility Studies; D007668:Kidney / Q000502:physiology; D016030:Kidney Transplantation / Q000502:physiology*; D008099:Liver / Q000502:physiology; D016031:Liver Transplantation / Q000502:physiology*; D008168:Lung / Q000502:physiology*; D016040:Lung Transplantation / Q000502:physiology*; D009927:Tissue and Organ Procurement / Q000379:methods*