title: Wnt not, waste not.
abstract: The molecular signals that regulate the regenerative function of satellite cells in the skeletal muscle remain largely obscure. In this issue of Cell Stem Cell, Brack et al. (2008) report that direct molecular crosstalk between stem cell self-renewal and differentiation pathways determines the timing and efficiency of muscle repair.
authors: Section on Developmental and Stem Cell Biology, Joslin Diabetes Center and the Harvard Stem Cell Institute, Boston, MA 02215, USA. amy.wagers@joslin.harvard.edu
authors: Amy J
authors: AJ
authors: Wagers
mesh_terms: D000818:Animals; D000943:Antigens, Differentiation; D002454:Cell Differentiation / Q000502:physiology*; D019070:Cell Lineage / Q000502:physiology; D004627:Embryonic Induction; D038362:Glycogen Synthase Kinase 3 / Q000378:metabolism / Q000502:physiology; D006801:Humans; D024510:Muscle Development; D018482:Muscle, Skeletal / Q000166:cytology / Q000502:physiology*; D051880:Receptors, Notch / Q000502:physiology*; D012038:Regeneration; D032496:Satellite Cells, Skeletal Muscle / Q000166:cytology / Q000502:physiology*; D015398:Signal Transduction; D013234:Stem Cells / Q000502:physiology; D051153:Wnt Proteins / Q000502:physiology*; D051176:beta Catenin
chemical_list: D000943:Antigens, Differentiation; D051880:Receptors, Notch; D051153:Wnt Proteins; D051176:beta Catenin; D038362:Glycogen Synthase Kinase 3