title: The value of narrow band imaging endoscope for early head and neck cancers.
abstract: OBJECTIVE
  To evaluate the diagnostic value of rhinolaryngoscopy using a narrow band imaging (NBI) system in detecting squamous cell carcinoma of the head and neck (SCCHN) in patients with esophageal cancer (EC).
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Between January 2006 and December 2006, 667 consecutive EC patients underwent rhinolaryngoscopy screening with both a white light and an NBI system. Sensitivity, specificity, accuracy, and positive/negative predictive values for detecting SCCHNs were calculated and compared.
  
  
  RESULTS
  Forty-five patients (6.7%) of 667 patients had SCCHNs. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for detecting SCCHNs by white light were 51.1 percent, 99.7 percent, 96.4 percent, 92 percent, and 96.6 percent. In contrast, those by NBI were 97.7 percent**, 98.9 percent, 98.8 percent*, 86.3 percent, and 99.8 percent** (*P < 0.01, **P < 0.001 vs white light).
  
  
  CONCLUSIONS
  An NBI endoscope significantly improves diagnostic accuracy, sensitivity, and negative predictive value in detecting SCCHN in EC patients. This endoscope would be highly beneficial in detecting superficial SCCHNs in high-risk patients.
authors: Department of Otolaryngology, Keiyukai Sapporo Hospital, Sapporo, Japan. akihito-watanabe@keiyukaisapporo.or.jp
authors: Akihito
authors: A
authors: Watanabe
authors: Masanobu
authors: M
authors: Taniguchi
authors: Hitoshi
authors: H
authors: Tsujie
authors: Masao
authors: M
authors: Hosokawa
authors: Masahiro
authors: M
authors: Fujita
authors: Shigeyuki
authors: S
authors: Sasaki
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D004867:Equipment Design; D004938:Esophageal Neoplasms; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D012680:Sensitivity and Specificity