title: Triptans: actions and reactions.
abstract: Subcutaneous sumatriptan is superior to placebo in achieving headache relief. Some commonly reported adverse events are paresthesias, tingling, and transient worsening of headache. Why do patients develop these symptoms? Our unique case may shed light on its actions.
authors: Thomas Jefferson University Hospital-Neurology, Philadelphia, PA 19107-5092, USA.
authors: Stephanie J
authors: SJ
authors: Nahas
authors: Stephen D
authors: SD
authors: Silberstein
mesh_terms: D000279:Administration, Cutaneous; D000284:Administration, Oral; D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D004087:Dihydroergotamine / Q000627:therapeutic use; D005260:Female; D006561:Herpes Simplex; D018258:Herpesvirus 2, Human; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy*; D051474:Neuralgia, Postherpetic / Q000139:chemically induced*; D011759:Pyrrolidines / Q000008:administration & dosage / Q000009:adverse effects; D017366:Serotonin Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D012867:Skin / Q000187:drug effects / Q000503:physiopathology; D018170:Sumatriptan / Q000008:administration & dosage / Q000009:adverse effects; D014363:Tryptamines / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D018712:Analgesics, Non-Narcotic; D011759:Pyrrolidines; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C115647:eletriptan; D004087:Dihydroergotamine; D018170:Sumatriptan