title: [Normal values in self-blood pressure measurement in relation to the presence of target organ disease. Data from the VAMPAHICA study].
abstract: OBJECTIVE
  International guides of hypertension (HT) recommend self-blood -pressure-measurement (SBPM) values higher than 135/85 mmHg to determine isolated clinical hypertension (ICH). This paper suggests a lower cut-off.
  
  
  METHODS
  This prospective, protocol-based study included 378 patients, 250 new hypertensive patients without previous treatment. Both SBPM and ambulatory blood pressure monitoring (ABPM) were measured in all patients. Risk factors and target organ disease (TOD) were evaluated by electrocardiography, renal function, microalbuminuria and retinography.
  
  
  RESULTS
  With a 135/85 mmHg ICH cut-off, only differences in serum creatinine levels (78.67 ICH vs 83.98 micromol/l sustained HT -SHT-; p = 0.03), grade I/II fundus oculi (FO) lesions (44.7 vs 62.8%; p = 0.009) and any FO lesions (48.2 vs 67.4%; p = 0.005) were found. With a ICH cut-off of 130/80 mmHg, a lower risk of grade III/IV FO lesions was found (RR = 0.59; 90% confidence interval [CI], 0.36-0.96; p = 0.06). Any TOD risk was related to SHT with a 130/85 mmHg cut-off (RR = 12.04; 90% CI, 1.03-140.28; p = 0.09).
  
  
  CONCLUSIONS
  Taking a 135/85 mmHg ICH cut-off, no differences in TOD between ICH and SHT were found. Taking a 130 mmHg ICH systolic blood pressure (SBP) cut-off, those who are below 130 mmHg have a lower risk of grade III/IV FO lesions. Those who are above this value have a higher TOD risk. Looking at TOD risk, we should consider a < 130 mmHg SBP cut-off for ICH diagnosis.
authors: ABS Anglès. Institut d'Assistència Sanitària, Girona, España. gcolld@meditex.es
authors: Gabriel
authors: G
authors: Coll-de-Tuero
authors: Quintí
authors: Q
authors: Foguet-Boreu
authors: Antonio
authors: A
authors: Rodriguez-Poncelas
authors: Ramón
authors: R
authors: Creus-Bosch
authors: Maria
authors: M
authors: Sanmartín-Albertos
authors: Marc
authors: M
authors: Saez-Zafra
authors: M Antònia
authors: MA
authors: Barceló-Radó
authors: Narcís
authors: N
authors: Salleras-Marcó
mesh_terms: D001795:Blood Pressure Determination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012016:Reference Values