Mechanistic insights and new products of the reaction of steroid sapogenins with NaNO2 and BF3.Et2O in acetic acid.
A detailed analysis of the course of the reaction of steroid sapogenins with NaNO(2) and BF(3).Et(2)O in acetic acid is presented and some evidences on the involved mechanism are provided. Two new products of the studied reaction were isolated and unambiguously characterized with the aid of NMR and single crystal X-ray diffraction.
López
Yliana
Y
Departamento de Química, Centro de Investigación y de Estudios Avanzados del IPN, 07000, Apdo, Postal 14-740, México, D.F., Mexico.
Ruíz-Pérez
Karen M
KM
Yépez
Rebeca
R
Santillan
Rosa
R
Flores-Alamo
Marcos
M
Iglesias-Arteaga
Martín A
MA
D019342:Acetic Acid / Q000737:chemistry*; D001880:Boranes / Q000737:chemistry*; D005027:Ethylene Oxide / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012502:Sapogenins / Q000737:chemistry*; D012977:Sodium Nitrite / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014961:X-Ray Diffraction
D001880:Boranes; D012502:Sapogenins; C021274:boron trifluoride; D005027:Ethylene Oxide; D012977:Sodium Nitrite; D019342:Acetic Acid