[Clinical characteristics and treatment of acute asthma exacerbations during pregnancy].
OBJECTIVE
To study the clinical characteristics of acute asthma during pregnancy, focusing on management of pregnant women presenting with an acute exacerbation.


METHODS
A prospective observational study was conducted in 30 cases of acute exacerbations during pregnancy.


RESULTS
The prognosis of 25 patients with mild or moderate asthma was good for both mother and fetus; none had severe complications. Among 5 women who had severe exacerbations, there were 4 pulmonary co-infections, 1 with respiratory acidosis, 1 with respiratory acidosis plus metabolic alkalosis, and 4 with fetal growth-restriction.


CONCLUSIONS
This study highlights that pregnancy can worsen asthma control in some women. Effective management and prevention of asthma exacerbations during pregnancy is key to ensuring the safety of the mother and the fetus.
Hu
Wen-sheng
WS
Department of Obstetrics, Affiliated Obstetric and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Zhang
Zhi-fen
ZF
D000208:Acute Disease; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000150:complications / Q000628:therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D011446:Prospective Studies
D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids