Water diffusion in cytoplasmic streaming in Elodea internodal cells under the effect of antimitotic agents.
The translational displacement of the cytoplasmic water in Elodea stem cells resulting from protein motor activity was measured using the NMR method. A 24-h treatment with vincristine results in a reduction of the translational displacement of the cytoplasmic water. With a constant cytoplasmic streaming velocity, the dynamics of the translational displacement of the cytoplasmic water under the effect of taxol are characterized by a continuous increase at a concentration of 0.05 mM, and reaching a plateau at a concentration of 0.5 mM.
Vorob'ev
Vladimir N
VN
Kazan Institute of Biochemistry and Biophysics, P.O.B. 30, 420111, Kazan, Russia. vorobyev@mail.knc.ru
Anisimov
Alexander V
AV
Dautova
Nailya R
NR
D050256:Antimitotic Agents / Q000008:administration & dosage*; D003595:Cytoplasmic Streaming / Q000187:drug effects / Q000502:physiology*; D004058:Diffusion; D031321:Hydrocharitaceae / Q000737:chemistry / Q000187:drug effects / Q000502:physiology*; D050257:Tubulin Modulators / Q000008:administration & dosage*; D014750:Vincristine / Q000008:administration & dosage*; D014867:Water / Q000737:chemistry / Q000378:metabolism*
D050256:Antimitotic Agents; D050257:Tubulin Modulators; D014867:Water; D014750:Vincristine