title: Variability of enzyme system of Nocardioform bacteria as a basis of their metabolic activity.
abstract: The present review describes some aspects of organization of biodegradative pathways of Nocardioform microorganisms, first of all, with respect to their ability to degrade aromatic compounds, mostly methylbenzoate, chlorosubstituted phenols, and chlorinated biphenyls and the intermediates of their transformation: 4-chlorobenzoate and para-hydroxybenzoate. Various enzyme systems induced during degradation processes are defined. The ability of microorganisms to induce a few key enzymes under the influence of xenobiotics is described. This ability may increase the biodegradative potential of strains allowing them to survive in the changing environment or demonstrate to some extent the unspecific response of microorganisms to the effect of toxicants. Nocardioform microorganisms responsible for degradation of such persistent compounds as polychlorinated biphenyls, polyaromatic hydrocarbons, chlorinated benzoates and phenols and other xenobiotics are characterized. The possibility of using Nocardioform microorganisms in some aspects of biotechnology due to their ability to produce some compounds important for industry is also estimated.
authors: Skryabin' Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Moscow, Russia.
authors: Inna P
authors: IP
authors: Solyanikova
authors: Vasilii M
authors: VM
authors: Travkin
authors: Darja O
authors: DO
authors: Rybkina
authors: Elena G
authors: EG
authors: Plotnikova
authors: Ludmila A
authors: LA
authors: Golovleva
mesh_terms: D000192:Actinomycetales / Q000201:enzymology* / Q000378:metabolism*; D001673:Biodegradation, Environmental; D002733:Chlorophenols / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism*; D006841:Hydrocarbons, Aromatic / Q000378:metabolism; D006846:Hydrocarbons, Halogenated / Q000378:metabolism; D015262:Xenobiotics / Q000378:metabolism
chemical_list: D002733:Chlorophenols; D004798:Enzymes; D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated; D015262:Xenobiotics