title: Growth process of small pancreatic carcinoma: a case report with imaging observation for 22 months.
abstract: This report describes serial observations of the growth process of a small invasive ductal carcinoma (IDC) of the pancreas from imaging studies. Histopathological studies showed IDC with macroscopic retention cysts proximal to an intraductal papillary-mucinous adenoma with mild atypia of the branch duct type in the pancreatic body, with no relation between the two lesions. IDC was demonstrated as an extremely low-echoic mass resembling a cyst with an unclear margin on the initial endoscopic ultrasonography. We misinterpreted the low-echoic mass as a benign intraductal mucinous-papillary neoplasm (IPMN) based on findings of other imaging studies, and the patient was followed-up. The mass increased from 7 mm to 13 mm in diameter over 22 mo, and remained smaller than 10 mm in diameter for about 420 d. The tumor volume doubling time was 252 d. The Ki67 labeling index was 15.9%, similar to that described in previous reports. Hence, IDC may grow slowly while remaining small.
authors: Department of Internal Medicine, Saku Central Hospital, 197 Usuda, Saku, Nagano 384-0301, Japan. thisa@r8.dion.ne.jp
authors: Takeshi
authors: T
authors: Hisa
authors: Hiroki
authors: H
authors: Ohkubo
authors: Satoshi
authors: S
authors: Shiozawa
authors: Hiroki
authors: H
authors: Ishigame
authors: Masato
authors: M
authors: Takamatsu
authors: Masayuki
authors: M
authors: Furutake
authors: Bunsei
authors: B
authors: Nobukawa
authors: Koichi
authors: K
authors: Suda
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D014463:Ultrasonography