title: The concentrations of methaemoglogin, carboxyhaemoglobin and some haematological parameters in tobacco snuff addicts in Igbo of Nigeria.
abstract: Methaemoglobin, carboxyhaemoglobin concentrations and some haematological parameters were studied in fifty tobacco snuff addicts (40 males and 10 females) in some villages of Anambra State, Nigeria. The aim was to investigate possible adverse effects of tobacco snuff in addicts in Igbos of Anambra State. Fifty apparently healthy persons (25 males and 25 females) who do not inhale snuff were used as controls. The age range of tests and control subjects was 25-65 years. The results showed no statistically significant difference when the tests group was compared with the control group. A comparison of the results on the basis of sex, age and period of exposure, showed no significant differences. Blood picture in test and control groups was normocytic and normochromic. The results suggest that tobacco snuff may not have any adverse effect on haemoglobin metabolism and erythropoiesis.
authors: Department of Medical Laboratory Science, College of Medicine, University of Nigeria, Enugu Campus, Enugu, Nigeria.
authors: S O
authors: SO
authors: Ureme
authors: I D
authors: ID
authors: Ibeagha
authors: I G
authors: IG
authors: Maduka
authors: O G
authors: OG
authors: Ibeagbulam
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D044383:Black People; D002263:Carboxyhemoglobin / Q000032:analysis*; D016022:Case-Control Studies; D004920:Erythropoiesis / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008706:Methemoglobin / Q000032:analysis*; D008875:Middle Aged; D009549:Nigeria; D018515:Plant Leaves; D013997:Time Factors; D014029:Tobacco Use Disorder / Q000097:blood* / Q000453:epidemiology; D014030:Tobacco, Smokeless / Q000009:adverse effects*
chemical_list: D015415:Biomarkers; D008706:Methemoglobin; D002263:Carboxyhemoglobin