High-intensity aerobic exercise improves diastolic function in coronary artery disease.
OBJECTIVE
To study the effect of aerobic treadmill exercise training with different intensity on left ventricular (LV) function in patients with stable coronary artery disease, using Strain Rate- and Tissue Doppler Imaging.


METHODS
Seventeen patients were randomly assigned to either moderate (50-60% of peak oxygen uptake (VO(2peak)) or high intensity exercise (80-90% of VO(2peak)) for 10 weeks.


RESULTS
The increase of VO(2peak) was significantly higher (p=0.01) in the high intensity group (17 vs. 8%). Mean LV early diastolic strain rate increased in the high, but not in the moderate, intensity group. For systolic strain rate or mitral annular velocities there were no change after training in either group.


CONCLUSIONS
Aerobic treadmill exercise improves early diastolic relaxation in patients with stable coronary artery disease, measured by the mean LV early diastolic strain rate.
Amundsen
Brage H
BH
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. brage.h.amundsen@ntnu.no
Rognmo
Øivind
Ø
Hatlen-Rebhan
Gudrun
G
Slørdahl
Stig A
SA
D000222:Adaptation, Physiological; D000368:Aged; D002302:Cardiac Output; D003327:Coronary Disease / Q000503:physiopathology* / Q000534:rehabilitation; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D016277:Ventricular Function, Left