[The use of the drug ginos in the treatment of out-patients with chronic progressive brain disorders].
Ginos, a derivative of extract Ginkgo Biloba, was administered to 100 patients, aged from 45 to 80 years, mean age 62,3+/-0,7), in dosage 120 mg 3 times daily during 3 months in addition to somatic therapy. A patient's state was assessed before, during and after the treatment using clinical methods and a battery of psychometric scales and neuropsychological tests. A significant improvement of neurological and mental status was found in 90 (90%) of patients that was most distinctly observed in the dynamics of their global state and neurocognitive performance on the MMSE and other tests. The effect of the drug was less pronounced for affective disorders - depression and anxiety. The drug was well-tolerated by patients.
Batysheva
T T
TT
Bagir'
L V
LV
Kostenko
E V
EV
Artemova
I Iu
IIu
Vdovichenko
T V
TV
Ganzhula
P A
PA
Zhuravleva
E Iu
EIu
Ismailov
A M
AM
Lisenker
L N
LN
Nesterova
O V
OV
Otcheskaia
O V
OV
Rotor
L D
LD
Khozova
A A
AA
Boĭko
A N
AN
D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D002908:Chronic Disease; D003071:Cognition / Q000187:drug effects; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D020441:Ginkgo biloba; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008609:Mental Status Schedule; D008875:Middle Aged; D010045:Outpatients; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use*; D011594:Psychometrics / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D028321:Plant Preparations