Real sample analysis on microfluidic devices.
This review covers the state of the art of the analysis of real (or non-ideal) samples on microfluidic devices. A real sample analysis performed on microfluidics conceptually involves the complete integration of sample preparation, analyte separation, and detection on these platforms. Different "lab-on-a-chip" approaches have emerged in relevant application areas such as clinical, environmental, and food analysis which will be critically illustrated and discussed with respect to the strengths and weakness found. Likewise, the main challenges and perspectives will also be commented on.
Crevillén
Agustin González
AG
Department of Analytical Chemistry and Chemical Engineering, University of Alcala, E-28871 Alcala de Henares, Madrid, Spain.
Hervás
Miriam
M
López
Miguel Angel
MA
González
Maria Cristina
MC
Escarpa
Alberto
A
D000818:Animals; D002624:Chemistry, Clinical / Q000379:methods; D004784:Environmental Monitoring / Q000379:methods; D005504:Food Analysis / Q000379:methods; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000379:methods*