title: Gold nanoparticles and oxidative stress in Mytilus edulis.
abstract: Little is known about potential environmental impact of nanoparticles. Gold nanoparticles can cause unexpected biological responses. Here, Mytilus edulis were exposed (24h) to gold-citrate nanoparticles (GNP), menadione and both compounds simultaneously (GNP/menadione). Protein ubiquitination and carbonylation were determined in gill, mantle and digestive gland, along with traditional oxidative stress biomarkers; catalase activity and neutral red retention time assay (haemolymph). 2DE gels were performed on gill proteins (menadione; GNP/menadione). Our results reveal that GNP may induce oxidative stress.
authors: Proteomics Research Group, Department of Biochemistry, Environmental Research Institute, University College Cork, Cork, Ireland.
authors: S
authors: S
authors: Tedesco
authors: H
authors: H
authors: Doyle
authors: G
authors: G
authors: Redmond
authors: D
authors: D
authors: Sheehan
mesh_terms: D000818:Animals; D005880:Gills / Q000187:drug effects; D006046:Gold / Q000633:toxicity*; D053768:Metal Nanoparticles / Q000633:toxicity*; D049880:Mytilus edulis / Q000187:drug effects* / Q000378:metabolism*; D018384:Oxidative Stress / Q000187:drug effects*; D024483:Vitamin K 3 / Q000633:toxicity
chemical_list: D024483:Vitamin K 3; D006046:Gold