Changes in prolactin in a highly organohalogen contaminated Arctic top predator seabird, the glaucous gull.
The factors influencing prolactin (PRL) variation in birds and in wildlife in general have rarely been investigated with respect to the physiological impacts of exposure to environmental contaminants. We investigated the associations between circulating baseline PRL levels and concentrations of eight persistent organohalogen contaminant (OHC) classes (i.e., major organochlorines and brominated flame retardants, and associated metabolic products) in blood (plasma) of free-ranging glaucous gulls (Larus hyperboreus), a top predator in the Norwegian Arctic, engaged in the process of incubation. We further examined whether plasma OHC concentrations were associated with the variation of PRL in glaucous gulls exposed to a standardized capture/restraint protocol. Plasma OHC concentrations in male glaucous gulls were 2- to 3-fold higher relative to females. Baseline PRL levels tended to be higher in females compared to males, although not significantly (p=0.20). In both males and females, the 30-min capture/restraint protocol led on average to a 26% decrease in PRL levels, which resulted in a rate of PRL decrease of 0.76 ng/mL/min. The baseline PRL levels and the rate of decrease in PRL levels tended to vary negatively with plasma OHC concentrations in males, but not in females, although several of these associations did not adhere with the criterion of significance (alpha=0.05). Present results suggest that in highly OHC-exposed male glaucous gulls, the control of PRL release may be affected by the direct or indirect modulating actions of OHCs and/or their metabolically derived products. We conclude that potentially OHC-mediated impact on PRL secretion in glaucous gulls (males) may be a contributing factor to the adverse effects observed on the reproductive behavior, development and population size of glaucous gulls breeding in the Norwegian Arctic.
Verreault
Jonathan
J
National Wildlife Research Centre, Science and Technology Branch, Environment Canada, Carleton University, Ottawa, Ont., Canada K1A 0H3. jonathan_verreault@carleton.ca <jonathan_verreault@carleton.ca>
Verboven
Nanette
N
Gabrielsen
Geir W
GW
Letcher
Robert J
RJ
Chastel
Olivier
O
D000818:Animals; D046091:Charadriiformes / Q000502:physiology*; D005260:Female; D006234:Handling, Psychological; D006846:Hydrocarbons, Halogenated / Q000097:blood / Q000633:toxicity*; D008297:Male; D011235:Predatory Behavior; D011388:Prolactin / Q000097:blood*; D012149:Restraint, Physical / Q000502:physiology; D012727:Sex Characteristics; D013315:Stress, Psychological / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000097:blood / Q000633:toxicity*
D006846:Hydrocarbons, Halogenated; D014874:Water Pollutants, Chemical; D011388:Prolactin