title: [Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement].
abstract: Sarcoidosis is a multisystemic disease which diagnosis depends on the presence of nonnecrotizing granulomas in the biopsy. However there are variants such as necrotizing sarcoidal granulomas or nodular sarcoidosis which have atypical findings and make difficult the differential diagnosis with other infectious processes. We describe a case of a man who develops granulomas with extensive necrosis in a systemic sarcoidosis that affected the lung and the central nervous system. This finding made us to make the diagnosis of tuberculosis and delay the specific treatment.
authors: Unidad de Enfermedades Sistémicas, Nuerología, Anatomía Patológica, Hospital Clínico San Cecilio, Granada. rriosfer@hotmail.com
authors: R
authors: R
authors: Ríos Fernández
authors: J L
authors: JL
authors: Callejas-Rubio
authors: M
authors: M
authors: Guerrero Fernández
authors: M M
authors: MM
authors: Serrano Falcón
authors: N
authors: N
authors: Ortego-Centeno
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003072:Cognition Disorders / Q000209:etiology; D003951:Diagnostic Errors; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009336:Necrosis; D011241:Prednisone / Q000627:therapeutic use; D012074:Remission Induction; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis; D014549:Urinary Incontinence / Q000209:etiology; D014717:Vertigo / Q000209:etiology
chemical_list: D000995:Antitubercular Agents; D011241:Prednisone; D008727:Methotrexate