title: Preimplantation genetic screening: "established" and ready for prime time?
abstract: Unless attempts to improve pregnancy rates and/or diminish miscarriage rates through preimplantation genetic screening (PGS) are applied to only carefully selected patients, they will fail. Because specific PGS indications have remained undefined, PGS should be considered an experimental procedure.
authors: Center for Human Reproduction, New York, New York 10021, USA. ngleicher@thechr.com
authors: Norbert
authors: N
authors: Gleicher
authors: Andrea
authors: A
authors: Weghofer
authors: David
authors: D
authors: Barad
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics / Q000517:prevention & control*; D001706:Biopsy / Q000009:adverse effects; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D005820:Genetic Testing / Q000941:ethics / Q000266:history; D049674:History, 21st Century; D006801:Humans; D008297:Male; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D011247:Pregnancy; D018873:Pregnancy Rate; D019836:Preimplantation Diagnosis / Q000941:ethics / Q000266:history; D015203:Reproducibility of Results; D027724:Reproductive Techniques, Assisted / Q000941:ethics / Q000266:history; D012743:Sex Preselection; D035703:Therapies, Investigational / Q000941:ethics / Q000266:history