[Eligibility of potential organ, tissue and cell donors regarding transmission of infection to recipient].
Organ/tissue/cell transplantation carries the risk of infection transfer from donor to recipient. Consecutive infections can be severe, lethal, and proceed to chronic condition without possibility of treating, treatable with known antimicrobial drugs. The possible consequences and infection development should be taken in consideration on planning the procedure. The risk of infectious disease transmission is estimated from patient history, evaluation of clinical documentation and microbiological test results. On routine evaluation of organ/tissue/cell donor, a number of tests are used: (1) serology (Anti-HIV 1, 2, HBsAg, Anti-HBc, Anti-HCV, and VDRL/RPR, TPHA, Anti-CMV, Anti-Coxackie B1 to B6 and Anti-QF in heart transplantation), (2) molecular methods (HBV, HIV, HCV) and (3) blood and urine culture. Based on the methods listed above, the donor is categorized in terms of eligibility for donation as eligible, eligible with individual consent, or ineligible.
Kalenić
Smilja
S
Klinicki bolnicki ceotar Zagreb, Referentni centar za bolnicke infekcije Ministarstva zdravstva i socijalne skrbi Republike Hrvatske, Zagreb, Hrvatska.
Budimir
Ana
A
D006801:Humans; D007239:Infections / Q000175:diagnosis / Q000635:transmission*; D012698:Serologic Tests; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D014180:Transplantation / Q000009:adverse effects*