title: Foamy histiocytes in a patient with visceral leishmaniasis after treatment with liposomal amphotericin B.
abstract: A seven-year-old patient was admitted to our hospital with the complaints of fever, malaise, and abdominal distention. In the bone marrow aspiration smears, leishmania amastigotes were observed. The patient was diagnosed as having visceral leishmaniasis (VL) and treated with liposomal amphotericin B (L-AMB). The authors report their observation of foamy histiocytes seen in the bone marrow aspiration smears of the patient with VL after L-AMB treatment. This effect of L-AMB needs to be recognized, since L-AMB may represent a further condition in addition to the other diseases that are associated with foamy histiocytes in the bone marrow.
authors: Unit of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors: Betül
authors: B
authors: Tavil
authors: Gülten
authors: G
authors: Seçmeer
authors: Hasan
authors: H
authors: Ozen
authors: Ali Bülent
authors: AB
authors: Cengiz
authors: Sule
authors: S
authors: Unal
authors: Aytemiz
authors: A
authors: Gürgey
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology* / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001853:Bone Marrow / Q000187:drug effects*; D001856:Bone Marrow Examination; D002648:Child; D005487:Foam Cells / Q000187:drug effects*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male
chemical_list: D000981:Antiprotozoal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B