[Improvement in visual acuity in a patient with ischaemic optic neuropathy (Horton arteritis) undergoing therapy with infliximab: a case report].
Ischaemic optic neuropathy is a serious illness, with uncertain prognosis, which typically afflicts elderly patients. The patient complains of a reduction of monolateral visus. Massive involvement of the papilla with whitish oedema is associated with Horton arteritis. We report a clinical case which has responded rapidly to therapy with infliximab, an anti-TNFalpha agent, and we evaluate the literature.
Benucci
Maurizio
M
Nuovo Ospedale S. Giovanni di Dio, Dipartimento Medicina Interna, U.O.S. Reumatologia, Firenze. maubenucci@tiscali.it
Manfredi
Mariangela
M
Puce
Fabrizio
F
Zuccarini
Silvio
S
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005451:Fluorescein Angiography; D013700:Giant Cell Arteritis / Q000188:drug therapy*; D006801:Humans; D000069285:Infliximab; D008297:Male; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects*; D014792:Visual Acuity / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab