title: Psychiatric comorbidity in adult patients with idiopathic generalized epilepsy.
abstract: We reviewed the medical records of 157 adult (18 years) patients with firmly diagnosed idiopathic generalized epilepsy (IGE) to investigate the extent and the type of psychiatric comorbidity and its relationship to various IGE syndromes and other epilepsy-related neurobiological factors. Forty-one patients (26.1%, 14 men and 27 women, median age: 34.0 years, range: 18-68, mean: 36.5) had comorbid mental disorders according to the 10th revision of the International Classification of Diseases (ICD-10) criteria, with four patients having a dual diagnosis. Mood disorders were the most common comorbid mental disorder (46.7%), followed by anxiety-panic disorder (26.7%). Comorbid psychiatric disorders occurred in all syndromes and in association with all seizure types, and, as in focal epilepsies, seizure control was significantly better in patients without psychiatric comorbidity (40.5% vs 19.5%, chi(2)(1)=5.873, P=0.015).
authors: Lambeth Rehabilitation Services, South London & Maudsley NHS Foundation Trust, London, UK. Nozomi.Akanuma@slam.nhs.uk
authors: Nozomi
authors: N
authors: Akanuma
authors: Eriko
authors: E
authors: Hara
authors: Naoto
authors: N
authors: Adachi
authors: Koichiro
authors: K
authors: Hara
authors: Michael
authors: M
authors: Koutroumanidis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004829:Epilepsy, Generalized / Q000453:epidemiology*; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D008875:Middle Aged