title: Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants.
abstract: Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.
authors: Laboratoire de Virologie, Centre National de Référence des Virus Entériques, Centre Hospitalier Universitaire de Dijon, 7 boulevard Jeanne d'Arc, 21079 Dijon Cedex, France. gael.belliot@u-bourgogne.fr
authors: Gaël
authors: G
authors: Belliot
authors: Amandine
authors: A
authors: Lavaux
authors: Donya
authors: D
authors: Souihel
authors: Davide
authors: D
authors: Agnello
authors: Pierre
authors: P
authors: Pothier
mesh_terms: D000818:Animals; D002460:Cell Line; D004202:Disinfectants / Q000494:pharmacology*; D008264:Macrophages / Q000821:virology; D051379:Mice; D050296:Microbial Viability; D029322:Norovirus / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D012367:RNA, Viral / Q000235:genetics; D038301:Virus Inactivation / Q000187:drug effects*
chemical_list: D004202:Disinfectants; D012367:RNA, Viral