[The effect of cerebrolysin on moderate cognitive impairment in cerebral vascular insufficiency (a clinical and electrophysiological study)].
The efficacy of cerebrolysin has been studied in 40 patients with cerebral vascular insufficiency and moderate cognitive impairment. The treatment in dosage of 10 ml cerebrolysin per 200 ml of physiological solution (20 intravenous injections daily) was effective in this group of patients. The course therapy with cerebrolysin reduced memory and attention disturbances improving the total cognitive status of patients. The data of clinical observations and neuropsychological testing have been confirmed by the results of electrophysiological study (cognitive event-related potential P300). The therapeutic effect had a delayed character being observed 3 month after completion of the treatment course.
Damulin
I V
IV
Koberskaia
N N
NN
Mkhitarian
E A
EA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000596:Amino Acids / Q000627:therapeutic use*; D001921:Brain / Q000098:blood supply* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D004334:Drug Administration Schedule; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D009483:Neuropsychological Tests; D012720:Severity of Illness Index
D000596:Amino Acids; D018696:Neuroprotective Agents; C006952:cerebrolysin