Chemosensory deprivation in juvenile coho salmon exposed to dissolved copper under varying water chemistry conditions.
Dissolved copper is an important nonpoint source pollutant in aquatic ecosystems worldwide. Copper is neurotoxic to fish and is specifically known to interfere with the normal function of the peripheral olfactory nervous system. However,the influence of water chemistry on the bioavailability and toxicity of copper to olfactory sensory neurons is not well understood. Here we used electrophysiological recordings from the olfactory epithelium of juvenile coho salmon (Oncorhynchus kisutch) to investigate the impacts of copper in freshwaters with different chemical properties. In low ionic strength artificial fresh water, a short-term (30 min) exposure to 20 microg/L dissolved copper reduced the olfactory response to a natural odorant (10(-5) M L-serine) by 82%. Increasing water hardness (0.2-1.6 mM Ca) or alkalinity (0.2-3.2 mM HCO3-) only slightly diminished the inhibitory effects of copper. Moreover, the loss of olfactory function was not affected by a change in pH from 8.6 to 7.6. By contrast, olfactory capacity was partially restored by increasing dissolved organic carbon (DOC; 0.1-6.0 mg/L). Given the range of natural water quality conditions in the western United States, water hardness and alkalinity are unlikelyto protect threatened or endangered salmon from the sensory neurotoxicity of copper. However, the olfactory toxicity of copper may be partially reduced in surface waters that have a high DOC content.
McIntyre
Jenifer K
JK
School of Aquatic and Fishery Sciences, University of Washington, Box 355020, 1122 NE Boat Street, Seattle, Washington 98105, USA.
Baldwin
David H
DH
Meador
James P
JP
Scholz
Nathaniel L
NL
D000818:Animals; D003300:Copper / Q000633:toxicity*; D009833:Olfactory Pathways / Q000187:drug effects*; D017684:Oncorhynchus kisutch / Q000502:physiology*; D012684:Sensory Thresholds / Q000187:drug effects*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D014874:Water Pollutants, Chemical; D003300:Copper