title: Pseudotumoral neuroparacoccidioidomycosis: one case report.
abstract: Neuroparacoccidioidomycosis is the central nervous system involvement by Paracoccidioides brasiliensis, a condition that may be underdiagnosed and has been scarcely reported. We describe a case of neuroparacoccidioidomycosis in a diabetic male with antecedent of heavy cigarette smoking and alcohol abuse. Thirty years before, he lived in the Amazon area and exerted rural activities in more recent years. The patient's main complaints were headache, visual deficit, hemiparesis, and weight loss. Imaging studies detected changes in the lungs and right adrenal gland, in addition to brain lesions. Paracoccidioides brasiliensis was found in tissue samples collected by the lung and brain biopsies. The patient is under ambulatory surveillance and in use of trimethoprim-sulfamethoxazole.
authors: Catholic University Medical Course and Department of Internal Medicine from HFA, Armed Forces Hospital (HFA), Brasilia, DF, Brazil. vitorinomodesto@gmail.com
authors: Vitorino Modesto
authors: VM
authors: dos Santos
authors: Rogério Martins
authors: RM
authors: Xavier
authors: Jacira Azevedo
authors: JA
authors: Cortes
authors: Ernesto Misael Cintra
authors: EM
authors: Osterne
authors: Maria
authors: M
authors: de Worisch Ferreira Lopes
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination