title: Focal uptake of Tc-99m MDP in a gossypiboma.
abstract: A 51-year-old Korean woman with a history of breast cancer underwent screening bone scintigraphy, which revealed minimal soft tissue uptake of Tc-99m methylene diphosphonate (MDP) in the right lower quadrant. CT and plain films confirmed that the uptake was due to a retained surgical sponge or gossypiboma. The incidence of gossypibomas has been reported at high as 1 in 1000 to 15,000 intra-abdominal operations. The natural progression of an aseptic gossypiboma is a foreign body reaction and granuloma formation. This inflammatory granulomatous reaction is the most likely cause of the extraosseous accumulation of Tc-99m MDP. This entity should be added to the already extensive list of etiologies of extraosseous MDP accumulation.
authors: Medical Corps, U.S. Navy, Battalion Surgeon, Camp Pendleton, California, USA.
authors: Bejoy G
authors: BG
authors: Thomas
authors: Eugene D
authors: ED
authors: Silverman
mesh_terms: D001062:Appendectomy / Q000009:adverse effects* / Q000295:instrumentation*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging* / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging; D015503:Surgical Sponges / Q000009:adverse effects*