24-hr blood pressure in HDT-bed rest and short-lasting space flight.
In 2 ESA-cosmonauts we compared the 24-hr profiles in blood pressure (BP) and heart rate (HR) to those that we had observed in an earlier head-down tilted (HDT) bed rest study. In view of the lack of gravitational stress, an attenuated profile was expected, as in HDT. To obtain a full profile we measured automatic upper-arm cuff measurements in 2 cosmonauts, combined with PortapresTM recordings in one. Unlike HDT, actual microgravity did not result in attenuated circadian profiles. The levels of systolic and diastolic pressures tended to be slightly lower in flight. Only nighttime heart rate was significantly lower in Space.
Karemaker
John M
JM
Academic Medical Center, University ofAmsterdam, Department of Systems Physiology, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands. j.m.karemaker@amc.uva.nl
Gisolf
Janneke
J
Stok
Wim J
WJ
van Montfrans
Gert A
GA
D001510:Bed Rest; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002302:Cardiac Output; D002319:Cardiovascular System / Q000503:physiopathology*; D002940:Circadian Rhythm; D018475:Head-Down Tilt; D006339:Heart Rate; D006801:Humans; D013026:Space Flight; D013318:Stroke Volume; D014655:Vascular Resistance; D014893:Weightlessness; D018474:Weightlessness Simulation