Linezolid lock prophylaxis of central venous catheter infection.
Central venous catheter (CVC)-related infections are a major problem for patients requiring long-term venous access and may result in frequent hospital admissions and difficulties in maintaining central venous access. CVC-related blood stream infections are associated with increased duration of inpatient stay and cost approximately Euro 13,585 per patient [Blot, S. I., Depuydt, P., Annemans, L., Benoit, D., Hoste, E., De Waele, J. J., Decruyenaere, J., Vogelaers, D., Colardyn, F. & Vandewoude, K. H. (2005). Clin Infect Dis 41, 1591-1598]. Antimicrobial lock therapy may prevent CVC-related blood stream infection, preserve central venous access and reduce hospital admissions. In this paper, the impact of linezolid lock prophylaxis in a patient with short bowel syndrome is described.
Fennell
Jérôme Patrick
JP
Department of Clinical Microbiology, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
O'Donohoe
Martin
M
Department of Surgery, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
Cormican
Martin
M
Department of Bacteriology, National University of Ireland Galway, Galway, Ireland.
Lynch
Maureen
M
Department of Clinical Microbiology, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.
D000081:Acetamides / Q000008:administration & dosage*; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis; D016470:Bacteremia / Q000382:microbiology / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000295:instrumentation; D002408:Catheters, Indwelling / Q000382:microbiology; D003030:Coagulase / Q000378:metabolism; D006801:Humans; D000069349:Linezolid; D008297:Male; D023303:Oxazolidinones / Q000008:administration & dosage*; D012778:Short Bowel Syndrome / Q000628:therapy; D013203:Staphylococcal Infections / Q000382:microbiology / Q000517:prevention & control*; D013210:Staphylococcus / Q000187:drug effects / Q000201:enzymology; D016896:Treatment Outcome
D000081:Acetamides; D000890:Anti-Infective Agents; D003030:Coagulase; D023303:Oxazolidinones; D000069349:Linezolid