Pseudocavitating bronchioloalveolar carcinoma followed over a decade.
A 38-year-old woman with bronchioloalveolar carcinoma (BAC) had a slow-growing cavitary nodule for nearly a decade. When she was hospitalized because of pneumonia 9 years earlier, a chest computed tomography scan showed a 1.5-cm cavitary right upper lobe nodule. At 1, 3, and 9 years computed tomography scans showed slow growth of the nodule to 2.4 cm, corresponding to a volume doubling time of 1494 days. Thoracoscopic biopsy and lobectomy were performed. Pathologic analysis revealed a well-differentiated mucinous BAC (T1N0M0). Pseudocavitation in solitary BAC is rare. A longer period of surveillance may be required to rule out malignancy in this setting. Surgical resection remains the mainstay of therapy.
Shaw
Jason P
JP
Department of Surgery, Division of Cardiothoracic Surgery, University of Miami Miller School of Medicine, Miami, Florida 33010, USA. jason.shaw@mssm.edu
Bejarano
Pablo A
PA
Thurer
Richard J
RJ
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D000328:Adult; D001707:Biopsy, Needle; D001999:Bronchoscopy / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods; D011014:Pneumonia / Q000175:diagnosis* / Q000188:drug therapy; D012307:Risk Factors; D013908:Thoracotomy / Q000379:methods; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome