title: Multiple myeloma with primary manifestation in the mandible: a case report.
abstract: Multiple myeloma is a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions in the vertebrae, ribs, pelvic bone, skull and jaw. We report on a clinical case of an 81-year-old male patient who presented with a tumefaction in the mandibular symphysis region, which had evolved over the previous seven months. In the radiographic examination, an extensive osteolytic lesion was observed in the region mentioned above. An incisional biopsy was performed and a histopathological study revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. During the bone gammagraphy a dissemination of the disease was detected in the scapula, clavicle and ribs. The diagnosis was multiple myeloma. Knowledge about the maxillofacial manifestations of multiple myeloma is important for the early diagnosis of the disease, since its primary form can manifest itself in the jaw. In the clinical case presented here, we highlight the interdisciplinarity needed to obtain a diagnosis and treatment of multiple myeloma.
authors: Universidade Federal da Paraíba/Brazil.
authors: Airton
authors: A
authors: Vieira-Leite-Segundo
authors: Marcelo Ferreira
authors: MF
authors: Lima Falcão
authors: Romualdo
authors: R
authors: Correia-Lins Filho
authors: Maria Sueli
authors: MS
authors: Marques Soares
authors: José
authors: J
authors: López López
authors: Eduardo
authors: E
authors: Chimenos Küstner
mesh_terms: D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D009101:Multiple Myeloma / Q000473:pathology*