title: In vitro noncontact intravascular femtosecond laser surgery in models of branch retinal vein occlusion.
abstract: OBJECTIVE
  To investigate intravenous femtosecond laser surgery in models of branch retinal vein occlusion.
  
  
  METHODS
  Non-amplified near infrared femtosecond laser was used to ablate polyamide sutures and human hairs inserted into the vascular lumina of porcine retinal veins in vitro. Specimens were subjected to multiphoton laser scanning microscopy and electron microscopy.
  
  
  RESULTS
  Regular laser cuts within sutures and hairs were detected with laser microscopy and electron microscopy. Neither laser microscopy nor histology revealed collateral damage of the vascular wall.
  
  
  CONCLUSIONS
  Non-amplified femtosecond lasers may allow precise atraumatic non-contact intravenous retinal surgery controlled by high-resolution imaging of the target.
authors: Department of Ophthalmology and Eye Hospital, University of Saarland, Homburg, Germany. doctorop@mail.ru
authors: Sergey
authors: S
authors: Toropygin
authors: Matthias
authors: M
authors: Krause
authors: Iris
authors: I
authors: Riemann
authors: Matthias
authors: M
authors: Hild
authors: Pedro
authors: P
authors: Mestres
authors: Berthold
authors: B
authors: Seitz
authors: Elena
authors: E
authors: Khurieva
authors: Klaus W
authors: KW
authors: Ruprecht
authors: Ursula
authors: U
authors: Löw
authors: Zisis
authors: Z
authors: Gatzioufas
authors: Karsten
authors: K
authors: König
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D007259:Infrared Rays; D053685:Laser Therapy / Q000379:methods*; D018613:Microscopy, Confocal; D046529:Microscopy, Electron, Transmission; D010865:Pilot Projects; D012169:Retinal Vein / Q000601:surgery* / Q000648:ultrastructure; D012170:Retinal Vein Occlusion / Q000473:pathology / Q000601:surgery*; D013552:Swine