Medical monitoring during the NASA Artificial Gravity-Bed Rest Pilot Study.
The NASA artificial gravity-bed rest pilot study (AGPS) was designed to investigate the efficacy of daily exposure to a +Gz acceleration gradient for counteracting the physiologic decrements induced by prolonged bed rest. Test subjects were continuously monitored by a physician for signs and symptoms of pre-syncope, motion sickness, and arrhythmias while on the centrifuge. In this article, we have summarized the medical monitoring observations that were made during the AGPS and included an assessment of the relative usefulness of the information provided by the various monitoring tools in making a decision to terminate a centrifuge spin.
Reinertson
Randal C
RC
University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA. rcreiner@utmb.edu
Nelson
Victor A
VA
Aunon
Serena M
SM
Schlegel
Todd T
TT
Lindgren
Kjell N
KN
Kerstman
Eric L
EL
Arya
Maneesh
M
Paloski
William H
WH
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001510:Bed Rest / Q000009:adverse effects*; D002498:Centrifugation / Q000009:adverse effects; D004867:Equipment Design; D019544:Equipment Failure Analysis; D018470:Gravity, Altered / Q000009:adverse effects; D018475:Head-Down Tilt; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation; D009041:Motion Sickness / Q000209:etiology; D018579:Patient Selection; D010865:Pilot Projects; D015203:Reproducibility of Results; D013026:Space Flight; D013575:Syncope / Q000209:etiology; D013997:Time Factors; D014481:United States; D018557:United States National Aeronautics and Space Administration; D018544:Weightlessness Countermeasures; D018474:Weightlessness Simulation