Is Ewing's sarcoma a stem cell tumor?
Solving the histogenesis of Ewing's sarcoma has defied investigators despite progress in understanding its molecular pathogenesis. In a recent issue of Cancer Cell, Tirode et al. (2007) present evidence supporting the hypothesis that this rare cancer arises from a primitive mesenchymal precursor.
Meltzer
Paul S
PS
Genetics Branch, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda MD 20892, USA. Electronic address: pmeltzer@mail.nih.gov.
D006801:Humans; D059630:Mesenchymal Stem Cells / Q000473:pathology*; D012512:Sarcoma, Ewing / Q000473:pathology*