title: Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction.
abstract: Treatment of differently protected and unprotected cysteines with a variety of alkenes in the presence of a radical initiator (AIBN) afforded the corresponding S-alkylated cysteines in high yields and without racemization.
authors: Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto Hahn Strasse 11, 44227 Dortmund, Germany.
authors: Gemma
authors: G
authors: Triola
authors: Luc
authors: L
authors: Brunsveld
authors: Herbert
authors: H
authors: Waldmann
mesh_terms: D000478:Alkylation; D003545:Cysteine / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D013438:Sulfhydryl Compounds; D003545:Cysteine