title: Extended-release oral drug delivery technologies: monolithic matrix systems.
abstract: Oral drug delivery is the largest and the oldest segment of the total drug delivery market. It is the fastest growing and most preferred route for drug administration. Use of hydrophilic matrices for oral extended release of drugs is a common practice in the pharmaceutical industry. This chapter presents different polymer choices for fabrication of monolithic hydrophilic matrices and discusses formulation and manufacturing variables affecting the design and performance of the extended-release product by using selected practical examples.
authors: Modified Release Technologies, Colorcon, West Point, PA, USA.
authors: Sandip B
authors: SB
authors: Tiwari
authors: Ali R
authors: AR
authors: Rajabi-Siahboomi
mesh_terms: D000818:Animals; D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems; D005079:Excipients / Q000737:chemistry*; D006801:Humans
chemical_list: D003692:Delayed-Action Preparations; D005079:Excipients