title: Cryptogenic organizing pneumonia associated with primary Sjogren's syndrome.
abstract: The association of cryptogenic organizing pneumonia (COP) with primary Sjogren's syndrome (PSS) is extremely rare. We report a case of simultaneous diagnosis of PSS and COP. A 70-year-old female presented with fever, non-productive cough and dyspnea of 2 months' duration. She had experienced sicca symptoms for the past 2 years. The chest radiograph revealed a right lower lobe infiltrate, which was unresponsive to antibiotics. Bronchoscopy, bronchoalveolar lavage and an open lung biopsy established the diagnosis of COP, while a lip biopsy was consistent with PSS. The patient improved on steroids. Organizing pneumonia may be one of the early manifestations of PSS. Exclusion of PSS should be part of a thorough evaluation of the patient with COP.
authors: Department of Pathophysiology, University of Athens Medical School, Laiko University Hospital, Athens, Greece.
authors: Savvas
authors: S
authors: Ioannou
authors: Sophie P
authors: SP
authors: Toya
authors: Periklis
authors: P
authors: Tomos
authors: George E
authors: GE
authors: Tzelepis
mesh_terms: D000368:Aged; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications* / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed