title: The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB.
abstract: BACKGROUND
  Since publication in 2000 of the Second International Consensus Report on Diagnosis and Classification of Epidermolysis Bullosa, many advances have been made to our understanding of this group of diseases, both clinically and molecularly. At the same time, new epidermolysis bullosa (EB) subtypes have been described and similarities with some other diseases have been identified.
  
  
  OBJECTIVE
  We sought to arrive at a new consensus of the classification of EB subtypes.
  
  
  RESULTS
  We now present a revised classification system that takes into account the new advances, as well as encompassing other inherited diseases that should also be included within the EB spectrum, based on the presence of blistering and mechanical fragility. Current recommendations are made on the use of specific diagnostic tests, with updates on the findings known to occur within each of the major EB subtypes. Electronic links are also provided to informational and laboratory resources of particular benefit to clinicians and their patients.
  
  
  CONCLUSIONS
  As more becomes known about this disease, future modifications may be needed. The classification system has been designed with sufficient flexibility for these modifications.
  
  
  CONCLUSIONS
  This revised classification system should assist clinicians in accurately diagnosing and subclassifying patients with EB.
authors: Vanderbilt University School of Medicine, Nashville, Tennessee; National Epidermolysis Bullosa Registry, Nashville, Tennessee, USA. Jo-David.Fine@vanderbilt.edu
authors: Jo-David
authors: JD
authors: Fine
authors: Robin A J
authors: RA
authors: Eady
authors: Eugene A
authors: EA
authors: Bauer
authors: Johann W
authors: JW
authors: Bauer
authors: Leena
authors: L
authors: Bruckner-Tuderman
authors: Adrian
authors: A
authors: Heagerty
authors: Helmut
authors: H
authors: Hintner
authors: Alain
authors: A
authors: Hovnanian
authors: Marcel F
authors: MF
authors: Jonkman
authors: Irene
authors: I
authors: Leigh
authors: John A
authors: JA
authors: McGrath
authors: Jemima E
authors: JE
authors: Mellerio
authors: Dedee F
authors: DF
authors: Murrell
authors: Hiroshi
authors: H
authors: Shimizu
authors: Jouni
authors: J
authors: Uitto
authors: Anders
authors: A
authors: Vahlquist
authors: David
authors: D
authors: Woodley
authors: Giovanna
authors: G
authors: Zambruno
mesh_terms: D004820:Epidermolysis Bullosa / Q000145:classification* / Q000175:diagnosis*; D006801:Humans