title: The contrasting presentation and management of pseudoangiomatous stromal hyperplasia of the breast.
abstract: Pseudoangiomatous stromal hyperplasia of the breast is a benign entity characterised by dense, collagenous proliferation of mammary stroma, forming interanastomosing capillary-like spaces lined by slender spindle cells. These spaces are not true vascular spaces, hence the term "pseudoangiomatous". We report two 14-year-old girls, who presented to us with pseudoangiomatous stromal hyperplasia of the breast. We believe that our patients represent two of the youngest ethnic Chinese females to be reported with this rare condition. The development of such a rapidly enlarging lesion often leads to anxiety and concern about malignancy, and emphasises the importance in appropriate diagnosis and management. We discuss the aetiology, clinical presentation, radiological and pathological features, as well as management of this unusual condition.
authors: Department of General Surgery, Changi General Hospital, 2 Simei Street 3, Singapore 529889. kevinksng@gmail.com
authors: K K
authors: KK
authors: Sng
authors: S M
authors: SM
authors: Tan
authors: J F
authors: JF
authors: Mancer
authors: K H
authors: KH
authors: Tay
mesh_terms: D000293:Adolescent; D000798:Angiomatosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001941:Breast Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D016462:Mammaplasty; D011859:Radiography; D017154:Stromal Cells / Q000473:pathology*