title: [Utility of inspiratory diagnostic CT scan after CT/PET study in the detection of pulmonary nodules].
abstract: We present the case of a 57-year old woman diagnosed of papillary thyroid carcinoma and treated with thyroidectomy followed by radioiodine (I-131) on two occasions. Follow-up radioiodine scan showed disease in right cervical region, confirmed by fine needle aspiration (FNA) and treated with lymphadenectomy. Due to thyroglobulin elevation, I-131 scan negative and inconclusive cervical ultrasonography/CT scan, we conducted a CT/PET study that confirmed cervical disease. An additional CT scan that was performed on maximum-inspiration showed four micro-nodules, one of which was not detected by the CT scan on shallow breathing (CT/PET). Post-treatment (I-131) scan confirmed uptake in these localizations. Good fusion between PET and CT images that avoids the errors of attenuation correction, especially in the lung bases, is necessary for correct image interpretation of the CT/PET study. Shallow breathing is necessary in order to obtain optimal image fusion with the CT/PET study, although this is not the best to evaluate pulmonary parenchyma in which an additional inspiratory CT scan improves detection of the pulmonary nodules.
authors: Unitat PET-TC, CETIR Esplugues, Esplugues de Llobregat, Barcelona, España.
authors: A
authors: A
authors: Mestre Fusco
authors: J R
authors: JR
authors: García Garzón
authors: M
authors: M
authors: Aránzazu Santana
authors: M
authors: M
authors: Simó Perdigó
authors: M
authors: M
authors: Soler Peter
authors: M
authors: M
authors: Buxeda
authors: F
authors: F
authors: Lomeña
mesh_terms: D005260:Female; D006801:Humans; D001239:Inhalation; D008875:Middle Aged; D049268:Positron-Emission Tomography; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*