title: Comparisons of metabolic syndrome definitions in four populations of the Asia-Pacific region.
abstract: BACKGROUND
  To compare the prevalence of metabolic syndrome (MetS) by four MetS definitions in four Asia-Pacific populations, and to compare the prevalence of individual metabolic components.
  
  
  METHODS
  Population-based cross-sectional studies from Australia, Japan, Korea, and Samoa were used to assess the World Health Organization (WHO), European Group for the Study of Insulin Resistance (EGIR), modified National Cholesterol Education Program Adult Treatment Panel III (modATPIII), and International Diabetes Federation (IDF) MetS definitions. Age-adjusted MetS prevalences were compared within and between countries and kappa statistics were used to determine the agreement between IDF and the other three definitions.
  
  
  RESULTS
  Japanese people had the lowest prevalence of MetS regardless of definition, and Samoans generally the highest prevalence. Age-adjusted prevalences for the four definitions ranged from 16% to 42% in Australia, 3% to 11% in Japan, 7% to 29% in Korea and 17% to 60% in Samoa. With the exceptions of Korean and Japanese males, the highest prevalence of MetS was obtained with the IDF definition. The best overall agreement with IDF MetS definition was for modATPIII, and the worst for EGIR. There were marked differences in the prevalence of MetS between the sexes, with no systematic pattern, and between the prevalences of individual metabolic components.
  
  
  CONCLUSIONS
  Differences in the prevalence of MetS and its components, using the various definitions, both within and between populations, indicate that caution is required when comparing studies from different countries. Determining the clinical significance of these differences will require prospective outcome studies.
authors: The George Institute for International Health, University of Sydney, Sydney, Australia. clee@george.org.au
authors: Crystal Man Ying
authors: CM
authors: Lee
authors: Rachel R
authors: RR
authors: Huxley
authors: Mark
authors: M
authors: Woodward
authors: Paul
authors: P
authors: Zimmet
authors: Jonathan
authors: J
authors: Shaw
authors: Nam H
authors: NH
authors: Cho
authors: Hyung Rae
authors: HR
authors: Kim
authors: Satu
authors: S
authors: Viali
authors: Makoto
authors: M
authors: Tominaga
authors: Dorte
authors: D
authors: Vistisen
authors: Knut
authors: K
authors: Borch-Johnsen
authors: Stephen
authors: S
authors: Colagiuri
mesh_terms: D000328:Adult; D000368:Aged; D001208:Asia / Q000453:epidemiology; D001315:Australia / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000145:classification* / Q000453:epidemiology*; D008875:Middle Aged; D011153:Population; D012107:Research Design; D012727:Sex Characteristics