[Spinal cord ischaemia and preoperative clopidogrel withdrawal in an arteriosclerotic patient].
We report the case of a motor impairment associated with bladder dysfunction several days after clopidogrel withdrawal in an arteriosclerotic woman scheduled for thoracotomy under general and thoracic epidural anaesthesia. Even if spinal artery syndrome may have a lot of aetiologies, we believe in a direct link between clopidogrel withdrawal and medulla ischaemia.
Murat
O
O
Département d'anesthésie réanimation, hôpital Robert-Debré, rue Alexis Carrel, 51092 Reims, France.
Durand
E
E
Delépine
G
G
Nguyen
P
P
Malinovsky
J-M
JM
D001161:Arteriosclerosis / Q000188:drug therapy; D000077144:Clopidogrel; D005260:Female; D006801:Humans; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D020760:Spinal Cord Ischemia / Q000139:chemically induced*; D013375:Substance Withdrawal Syndrome; D013988:Ticlopidine / Q000009:adverse effects / Q000031:analogs & derivatives*
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine