title: [Effect of prophylactic device "Braslet" on hemodynamic changes during long-term missions to orbital station Mir].
abstract: The benefit from occlusive cuffs (prophylactic device Braslet) to human hemodynamics was evaluated in seven cosmonauts on long-term Mir missions using the ultrasonic technique (Echography and Doppler). Braslet had a positive effect on cosmonauts" state of health during the first month of flight. Improvement of cerebral hemodynamics was attested objectively by reduction of venous congestion. However, the device did not produce a noticeable effect on the leg vein expansibility and capacity at the beginning of long-term mission. Starting on flight month 3, cumulation of the Braslet effect on the leg large veins resulted in progressive vein expansion. Regular wearing of the Braslet device produced changes in expansibility, capacity and elasticity of the veins in lower extremities. Extent of these changes was dependent on period of Braslet application and tightness of occlusion. Though the state of leg veins of the cosmonauts who had been favourable to Braslet during mission did not appear changed after landing, still we cannot make the conclusion that the occlusive cuffs do not bring harm if worn continuously, as their delayed effects have not been evaluated and remain unknown.
authors: G A
authors: GA
authors: Fomina
authors: A R
authors: AR
authors: Kotovskaia
authors: E V
authors: EV
authors: Temnova
mesh_terms: D000328:Adult; D000337:Aerospace Medicine / Q000295:instrumentation*; D018480:Astronauts; D004867:Equipment Design; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D020896:Hypovolemia / Q000503:physiopathology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D011379:Prognosis; D018531:Spacecraft; D013997:Time Factors