title: Zolpidem extended-release: therapy for sleep induction and sleep maintenance difficulties.
abstract: BACKGROUND
  Insomnia is a highly prevalent condition that is associated with significant morbidity. Those who suffer from this condition commonly report impairment in daytime functioning, and may be at risk for the development of co-morbid illnesses, including psychiatric illnesses such as depression. Although primary and co-morbid insomnias are presented to clinicians in healthcare settings, physicians may need to apply direct inquiry in order to elicit patient reports of insomnia.
  
  
  OBJECTIVE
  To present information that helps clinicians to identify, evaluate, and treat patients with insomnia.
  
  
  METHODS
  Original research and reviews published in the peer-reviewed literature were considered and cited in this manuscript.
  
  
  CONCLUSIONS
  Insomnia is an under-recognized condition. However, the significant morbidity associated with it warrants the attention of healthcare providers. There are sound methods that can be used in the evaluation of insomnia that allow clinicians to render differential diagnoses, ultimately enabling them to consider the use of the effective and safe treatments available today.
authors: Clinilabs, Inc., 423 W. 55th Street/4th Floor, New York, NY 10019, USA. gzammit@clinilabs.com
authors: Gary
authors: G
authors: Zammit
mesh_terms: D003692:Delayed-Action Preparations; D006801:Humans; D011725:Pyridines / Q000008:administration & dosage* / Q000009:adverse effects / Q000378:metabolism; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*; D000077334:Zolpidem
chemical_list: D003692:Delayed-Action Preparations; D011725:Pyridines; D000077334:Zolpidem