Is charge reduction in ESI really necessary?
The technique of charge reduction electrospray mass spectrometry (CREMS), which can reduce the charge state complexity produced in electrospray ionization (ESI), is discussed.
Smith
Lloyd M
LM
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706-1396, USA. smith@chem.wisc.edu
D010449:Peptide Mapping / Q000379:methods* / Q000639:trends*; D020543:Proteome / Q000737:chemistry*; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods* / Q000639:trends*; D055672:Static Electricity; D014481:United States
D020543:Proteome