title: Virtual colonoscopy: effect of computer-assisted detection (CAD) on radiographer performance.
abstract: OBJECTIVE
  To investigate the effect of a virtual colonoscopy (VC) computed-assisted detection (CAD) system on polyp detection by trained radiographers.
  
  
  METHODS
  Four radiographers trained in VC interpretation and utilization of CAD systems read a total of 62 endoscopically validated VC examinations containing 150 polyps (size range 5-50mm) in four sessions, recording any polyps found and the examination interpretation time, first without and then with the addition of CAD as a "second reader". After a temporal separation of 6 weeks to reduce recall bias, VC examinations were re-read using "concurrent reader" CAD. Interpretation times, polyp detection, and number of false-positives were compared between the different reader paradigms using paired t and paired exact tests.
  
  
  RESULTS
  Overall, use of "second reader" CAD significantly improved polyp detection by 12% (p<0.001, CI 6%,17%)) from 48 to 60%. There was no significant improvement using CAD as a concurrent reader (p=0.20; difference of 7%, CI -3%, 16%) and no significant overall difference in recorded false-positives with second reader or concurrent CAD paradigms compared with unassisted reading (p=0.25 and 0.65, respectively). The mean interpretation time was 21.7 min for unassisted reading, 29.6 (p<0.001) min for second reader and 19.1 min (p=0.12) for concurrent reading paradigms.
  
  
  CONCLUSIONS
  CAD, when used as a second reader, can significantly improve radiographer reading performance with only a moderate increase in interpretation times.
authors: St Mark's Hospital, Harrow, Middlesex, UK. burlingdavid@yahoo.co.uk
authors: D
authors: D
authors: Burling
authors: A
authors: A
authors: Moore
authors: M
authors: M
authors: Marshall
authors: J
authors: J
authors: Weldon
authors: C
authors: C
authors: Gillen
authors: R
authors: R
authors: Baldwin
authors: K
authors: K
authors: Smith
authors: P J
authors: PJ
authors: Pickhardt
authors: P
authors: P
authors: Pickhardt
authors: L
authors: L
authors: Honeyfield
authors: S A
authors: SA
authors: Taylor
authors: S
authors: S
authors: Taylor
mesh_terms: D002983:Clinical Competence; D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008505:Medical Staff, Hospital / Q000592:standards*; D011857:Radiographic Image Interpretation, Computer-Assisted; D015203:Reproducibility of Results; D012189:Retrospective Studies