Selective vasodilatation effect of sargahydroquinoic acid, an active constituent of Sargassum micracanthum, on the basilar arteries of rabbits.
Sargahydroquinoic acid (2), a major active constituent of Sargassum micracanthum collected from the coast of the East Sea in Korea, showed a selective vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with sargahydroquinoic acid may selectively accelerate cerebral blood flow through dilatation of the basilar artery without lowering systemic blood pressure.
Park
Byong-Gon
BG
College of Medicine, Kwandong University, Gangneung, Gangwon 210-701, Republic of Korea.
Shin
Woon-Seob
WS
Um
Yumi
Y
Cho
Sungsik
S
Park
Gab-Man
GM
Yeon
Dong-Soo
DS
Kwon
Seong-Chun
SC
Ham
Jungyeob
J
Choi
Byoung Wook
BW
Lee
Seokjoon
S
D000475:Alkenes / Q000737:chemistry* / Q000494:pharmacology*; D000818:Animals; D001488:Basilar Artery / Q000187:drug effects*; D016227:Benzoquinones / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D011817:Rabbits; D044647:Sargassum / Q000737:chemistry; D014664:Vasodilation / Q000187:drug effects
D000475:Alkenes; D016227:Benzoquinones; C528847:sargahydroquinoic acid