[Immunity to poliomyelitis in adult population of Moscow region. Role of vaccine and wild polioviruses in its formation].
Assessment of immunity to poliomyelitis in adults from 8 towns of Moscow region was conducted. Low levels of population immunity against some serotypes of poliovirus in several towns have been found. At the same time, these levels were high and very high in other towns. Measurement of levels of strain-specific antibodies to vaccine and wild polioviruses demonstrated wide circulation of wild polioviruses during past decades which had significant influence on formation of immunity. Substantial number of non-immune adults represents favorable conditions for circulation of vaccine polioviruses after cessation of vaccination, which, in its turn, could result in reestablishment of their neurovirulent properties and subsequent reemergence of poliomyelitis.
Seĭbil'
V B
VB
Malyshkina
L P
LP
Lavrova
I K
IK
Efimova
V F
VF
Tamazian
G V
GV
Kaiumova
L I
LI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D000918:Antibody Specificity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011051:Poliomyelitis / Q000276:immunology* / Q000517:prevention & control; D017955:Poliovirus / Q000145:classification / Q000276:immunology*; D023321:Poliovirus Vaccines / Q000145:classification / Q000276:immunology*; D012424:Rural Population; D012426:Russia; D014019:Tissue Donors
D000914:Antibodies, Viral; D023321:Poliovirus Vaccines