Hospital-associated infections during and after care in a paediatric infectious disease ward.
Viruses are important causes of paediatric hospital-associated infections (HAIs). We evaluated the frequency of viral HAIs during hospitalisation and after discharge in a paediatric infection ward. Data were collected prospectively for two years with follow-up questionnaires in which parents reported symptoms of new infections. Infections occurring >72 h after admission to hospital or <72 h after discharge were regarded as hospital-associated. The mean age of patients was 3.0 years and the mean hospitalisation time 3.0 days. Twenty-one out of the 1927 patients [1.1%, 95% confidence interval (CI): 0.7-1.7] developed an HAI during hospitalisation, in every case diarrhoea. A total of 1175 (61%) questionnaires were returned. In all, 86 children (7.3%, 95% CI: 5.9-9.0) had new symptoms within 72 h of discharge, most often diarrhoea (49%). Older age protected against HAI [odds ratio (OR, per year in age): 0.92; 95% CI: 0.85-0.99; P=0.02]. Among the patients hospitalised for respiratory infections, a shared room increased the risk of HAI (OR: 2.3; 95% CI: 1.1-4.8; P=0.03). Eight percent of the patients in our ward, where alcohol hand gel is actively used and single rooms are common, developed an HAI. Eighty percent of the HAIs appeared at home, which emphasises the importance of post-discharge follow-up.
Kinnula
S E
SE
Department of Paediatrics, University of Oulu, Oulu, Finland.
Renko
M
M
Tapiainen
T
T
Knuutinen
M
M
Uhari
M
M
D000256:Adenoviridae / Q000302:isolation & purification; D002675:Child, Preschool; D003141:Communicable Diseases / Q000453:epidemiology* / Q000821:virology; D003428:Cross Infection / Q000453:epidemiology* / Q000821:virology; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D005243:Feces / Q000821:virology; D006757:Hospital Units; D006801:Humans; D010372:Pediatrics; D016012:Poisson Distribution; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology; D012307:Risk Factors; D012401:Rotavirus / Q000302:isolation & purification; D018571:Sentinel Surveillance; D011795:Surveys and Questionnaires; D013997:Time Factors