title: AP-ROP in an infant with minimal oxygen exposure.
abstract: Retinopathy of prematurity (ROP) is a multifactorial disease affecting the developing retinal vasculature and remains an important cause of blindness in very preterm infants. Rush disease, or aggressive posterior ROP (AP-ROP), progresses rapidly to stage 5 disease without exhibiting the classical course that includes stages 1-3. We describe an infant with minimal exposure to oxygen who developed AP-ROP that led to bilateral retinal detachments and a poor visual outcome, despite following current recommended screening guidelines.
authors: Newborn Services, National Women's Health, Auckland District Health Board, Auckland, New Zealand. mariamb@adhb.govt.nz
authors: Mariam J
authors: MJ
authors: Buksh
authors: Shuan
authors: S
authors: Dai
authors: Carl A
authors: CA
authors: Kuschel
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D045422:Continuous Positive Airway Pressure; D004921:Erythropoietin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000188:drug therapy; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D008028:Light Coagulation; D008297:Male; D015997:Neonatal Screening; D010100:Oxygen / Q000008:administration & dosage / Q000009:adverse effects; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D004921:Erythropoietin; D010100:Oxygen