Biomechanical evaluation of microbial cellulose (Zoogloea sp.) and expanded polytetrafluoroethylene membranes as implants in repair of produced abdominal wall defects in rats.
OBJECTIVE
To evaluate the Load of Rupture of implants of membranes of microbial cellulose (Zoogloea sp.) and extended polytetrafuoroethylene in sharp defects of abdominal wall of rats.


METHODS
Sixty Wistar male rats, with a mean weight of 437,7 g +/- 40,9, anesthetized by a mixture of ketamine (5mg/100g) and xylazine (2mg/100g), were submitted to a rectangular (2 x 3 cm) excision of the abdominal wall, including fascia, muscle and peritoneum, and treated with membranes of microbial cellulose (MC) (MC Group- 30 animals) or extended polytetrafluoroethylene (ePTFE) (ePTFE Group- 30 animals). Each group was subdivided in 14th POD, 28th POD and 60th POD Subgroups. Under anesthesia, animals were submitted to euthanasia at 14th POD, 28th POD and 60th POD for evaluation of Load of Rupture.


RESULTS
Load of Rupture levels were significantly elevated (p<0, 05) among 14th, 28th and 60th postoperative days from each Group. When compared between groups, values of Load of Rupture were significantly larger (p<0, 05) in ePTFE Group than in MC Group.


CONCLUSIONS
Resistance to strength at implant/host interface was more pronounced in PTFEe Group than in MC Group.
Falcão
Suyiene Cordeiro
SC
Department of Veterinary Medicine, Federal Rural University of PernambucoBrazil.
Coelho
Antônio Roberto de Barros
AR
Evêncio Neto
Joaquim
J
D000007:Abdominal Injuries / Q000601:surgery; D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002482:Cellulose / Q000627:therapeutic use*; D008297:Male; D008422:Materials Testing; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013718:Tensile Strength / Q000502:physiology*; D013997:Time Factors; D015045:Zoogloea
D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D002482:Cellulose