title: Positron emission tomography/computed tomography as a method for detection and monitoring of laryngeal chondritis.
abstract: Infections of the laryngeal cartilages occur clinically as local pain, dysphonia, dysphagia or dyspnoea and may lead to destruction of the laryngeal skeleton. We present positron emission tomography/computed tomography (PET-CT) as a new method for detection and monitoring of laryngotracheal chondritis. We prospectively analyzed all patients undergoing PET-CT examination, of whom we were clinically suspicious of laryngeal cartilage chondritis. When a chondritis had been confirmed by PET, therapy was started, and the course of inflammation was monitored. Three patients were selected, where application of PET is demonstrated. We analyzed nine patients, five of them suffering from a present or past cancerous disease of the neck region. Four patients suffered from symptoms that occurred after percutaneous tracheotomy and long-term intubation. Chondritis of the laryngeal skeleton or upper parts of the trachea was diagnosed in seven of nine subjects by using PET-scan. PET-CT provides a reliable tool in diagnosis of laryngeal cartilage chondritis. Furthermore, it is an excellent tool in monitoring objectively presence and grade of an infection. This may play a decisive role in tracheal surgery or to estimate success of conservative therapy.
authors: Ear, Nose and Throat (ENT) University Hospital, Department of Phoniatrics, Speech and Swallowing, Medical University of Graz, Auenbruggerplatz 26-28, 8036, Graz, Austria. markus.gugatschka@klinikum-graz.at
authors: Markus
authors: M
authors: Gugatschka
authors: Thomas
authors: T
authors: Schwarz
authors: Gerhard
authors: G
authors: Friedrich
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis; D002357:Cartilage Diseases / Q000150:complications*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications* / Q000175:diagnosis*; D007822:Laryngeal Neoplasms / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18