title: [Colloidal carbon particles in the noninstrumental diagnostic systems].
abstract: A technology has been developed to design test systems based on the one-stage determination of the conjugate containing the ligand-determined stereospecific compound that is covalently conjugated with colloidal carbon particles. Due to the high optical density of such conjugates in the visible light spectrum region, a ligand may be directly visually inspected as black spots (dots), stripes, or the arbitrary pattern ("+", "-") onto the work surface of a solid phase, which forms after a short (minutes) time of addition of a conjugate regardless of the format of analytical system. These systems may be effectively used in various tests in the ambulatory, hospital, and prehospital settings, including extreme clinical and epidemiological cases, as well as in various household and field diagnostic kits.
authors: M B
authors: MB
authors: Raev
mesh_terms: D002244:Carbon / Q000737:chemistry*; D004338:Drug Combinations; D006801:Humans; D007159:Immunologic Tests / Q000295:instrumentation* / Q000379:methods*; D011205:Povidone / Q000737:chemistry*; D011934:Reagent Strips / Q000737:chemistry*; D012680:Sensitivity and Specificity
chemical_list: D004338:Drug Combinations; D011934:Reagent Strips; C078073:carbon colloid; D002244:Carbon; D011205:Povidone