[Gastroduodenal erosive and ulcerous lesions induced by non-steroidal antiinflammatory drugs].
The article presents systematized modern data on erosive and ulcerous lesions of the gastric mucosa (GM) and the duodenal mucosa (DM) induced by non-steroidal anti-inflammatory drugs (NSAID), on their ethiology and multifactor pathogenesis. Diagnostic and therapeutic methods are substantiated. The authors discuss debatable issues concerning the terminology of GM and DM lesions, the role played by Helicobacter pylori, and prospective preventive and therapeutic methods, and substantiate their position on debatable issues.
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D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D004381:Duodenal Ulcer / Q000139:chemically induced* / Q000517:prevention & control; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects; D011379:Prognosis; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000517:prevention & control
D000894:Anti-Inflammatory Agents, Non-Steroidal