title: [Polymethylene nucleic acid derivatives with omega-functional groups: vi. [8-(2-oxocyclohexyl)-9-oxooctyl]pyrimidines as potential inhibitors of pyrimidine phosphorylases].
abstract: New polymethylene derivatives of nucleic bases with beta-diketo function in omega-position were prepared by alkylation of uracil, thymine, and cytosine. Their physicochemical properties and effect on the E. coli uridine phosphorylase were studied.
authors: V V
authors: VV
authors: Komissarov
authors: N G
authors: NG
authors: Panova
authors: A M
authors: AM
authors: Kritsyn
mesh_terms: D004926:Escherichia coli / Q000201:enzymology*; D009696:Nucleic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry*; D014543:Uridine Phosphorylase / Q000037:antagonists & inhibitors* / Q000737:chemistry
chemical_list: D009696:Nucleic Acids; D011743:Pyrimidines; D014543:Uridine Phosphorylase