[The use of Stalevo in Hungary for patients with Parkinson disease and its effect on the quality of life].
The triple combination of levodopa, DDCI and entacapone (Stalevo) is used to treat motor complication in Parkinsonian patients with fluctuation. An observational investigation has been conducted in Hungary to study the effects of Stalevo on the "wearing off" phenomenon and on the quality of life in patients, who are to be treated with. The introduction of Stalevo to the treatment resulted in no changes in the number of patients taking selegiline, amantadine and dopamine agonists, while the number of patients taking anticholinergic drugs were slightly increased. This treatment significantly decreased the average Hoehn-Yahr stadium, as well as the non-motor symptoms, without any remarkable side effect. Stalevo also improved the quality of life, detected by the EQ-5D questionnaire and the visual analogue scale.
Klivényi
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Szegedi Tudományegyetem, Neurológiai Klinika, Szeged. klivenyi@nepsy.szote.u-szeged.hu
Vécsei
László
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D000328:Adult; D000368:Aged; D000547:Amantadine / Q000008:administration & dosage; D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002230:Carbidopa / Q000008:administration & dosage / Q000627:therapeutic use*; D002396:Catechols / Q000008:administration & dosage / Q000627:therapeutic use*; D018680:Cholinergic Antagonists / Q000008:administration & dosage; D018491:Dopamine Agonists / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006814:Hungary; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D011788:Quality of Life; D012642:Selegiline / Q000008:administration & dosage; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome
D000978:Antiparkinson Agents; D002396:Catechols; D018680:Cholinergic Antagonists; D018491:Dopamine Agonists; D004338:Drug Combinations; C481098:Stalevo; D012642:Selegiline; D007980:Levodopa; D000547:Amantadine; D002230:Carbidopa