Cheilitis granulomatosa associated with allergic contact dermatitis to betel quid.
Cheilitis granulomatosa (CG) is a rare disorder of unknown origin, which is characterized clinically by painless, recurrent or persistent swelling of 1 or both lips. Betel quids, composed of betel nuts (seeds of the Areca catechu), slake lime, and Piper betel leaf/or Piper betel inflorescence, are widely used in Asia and strongly associated with oral mucosal disease. It has also been found to be a cause of contact leukomelanosis because of its ingredients of various chemicals. We describe a case of CG induced by betel quid chewing.
Chiu
Cheng-Sheng
CS
Department of Dermatology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan.
Tsai
Yi-Lun
YL
D000328:Adult; D001114:Areca; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008409:Mastication; D008556:Melkersson-Rosenthal Syndrome / Q000139:chemically induced*; D010328:Patch Tests; D031721:Piper betle / Q000009:adverse effects*; D035261:Plant Components, Aerial / Q000009:adverse effects*