title: Rapid correction of hypokalemia in a patient with an implantable cardioverter-defibrillator and recurrent ventricular tachycardia.
abstract: We present the case of a 74-year-old man with non-ischemic dilatated cardiomyopathy and an implantable cardioverter-defibrillator presenting with a serum potassium of 2.6 mmol/L, recurrent unstable ventricular tachycardia, and multiple defibrillations. Administration of a rapid bolus of 20 mEq KCL solution via central venous access, followed by an additional total of 80 mEq (orally and intravenously [i.v.]) over the next 2 h, resulted in immediate resolution of his recurrent unstable dysrhythmia without toxic side effects. Guidelines for rapid correction of hypokalemia quote a maximum safe administration of 20 mEq i.v./h. In addition to discussing the clinical relevance and physiologic interactions of the variables leading to this patient's presentation, we discuss the successful termination of his sustained recurrent ventricular dysrhythmia by rapid potassium repletion above currently recommended rates. The patient we present is representative of a growing population, given medical and technological advances over the years. Potassium boluses may be reasonable in such circumstances, particularly in patients with ICDs.
authors: Department of Cardiology, Brooke Army Medical Center, San Antonio, Texas 78209, USA.
authors: David A
authors: DA
authors: Philips
authors: Terry D
authors: TD
authors: Bauch
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000628:therapy; D017147:Defibrillators, Implantable; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D004573:Electrolytes / Q000008:administration & dosage*; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D007262:Infusions, Intravenous; D008297:Male; D011189:Potassium Chloride / Q000008:administration & dosage*; D017180:Tachycardia, Ventricular / Q000150:complications / Q000188:drug therapy*
chemical_list: D004573:Electrolytes; D011189:Potassium Chloride