title: Phytochemical investigation on leaf extract of Cordia salicifolia Cham.
abstract: The dichloromethane extract of leaves of Cordia salicifolia Cham. (Family Boraginaceae) was fractionated by SiO(2) column chromatography and analyzed by gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The apolar extract is characterized by a very high content of (+)-spathulenol (0.53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL).
authors: Dipartimento di Scienze del Farmaco, University G. D'Annunzio, Chieti Scalo, Italy. lmenghini@unich.it
authors: Luigi
authors: L
authors: Menghini
authors: Francesco
authors: F
authors: Epifano
authors: Lidia
authors: L
authors: Leporini
authors: Rita
authors: R
authors: Pagiotti
authors: Bruno
authors: B
authors: Tirillini
mesh_terms: D005591:Chemical Fractionation; D002849:Chromatography, Gas; D031213:Cordia / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D016480:Helicobacter pylori / Q000187:drug effects / Q000254:growth & development; D009682:Magnetic Resonance Spectroscopy; D008752:Methylene Chloride; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis
chemical_list: D010936:Plant Extracts; D012717:Sesquiterpenes; D008752:Methylene Chloride; C013258:spathulenol