title: Measuring noncalcified coronary atherosclerotic plaque using voxel analysis with MDCT angiography: phantom validation.
abstract: OBJECTIVE
  This purpose of this study was to evaluate the accuracy and reproducibility of a voxel analysis technique for measuring noncalcified plaque in the coronary arteries.
  
  
  METHODS
  Polyethylene phantoms representing noncalcified plaque were scanned in both MDCT and micro-CT scanners and inter- and intrareader variability of volume calculation was performed.
  
  
  RESULTS
  Volume measurements by both MDCT and micro-CT were comparable to the true volume as measured by micrometry (< 3%, p = 0.05).
  
  
  CONCLUSIONS
  There appears to be no significant difference (< 3%) between MDCT and micro-CT measurements.
authors: Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, One Deaconess Rd., WCC-302, Boston, MA 02215, USA.
authors: Adeel
authors: A
authors: Sabir
authors: Chun-Shan
authors: CS
authors: Yam
authors: Norihiko
authors: N
authors: Yoshimura
authors: Jacqueline L
authors: JL
authors: Buros
authors: Alec M
authors: AM
authors: De Grand
authors: Vassilios
authors: V
authors: Raptopoulos
authors: Melvin E
authors: ME
authors: Clouse
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D006801:Humans; D021621:Imaging, Three-Dimensional; D019047:Phantoms, Imaging; D011095:Polyethylenes; D011857:Radiographic Image Interpretation, Computer-Assisted; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed
chemical_list: D011095:Polyethylenes