title: N-metalated imines by reaction of 1,1-diethoxybut-2-ene with aromatic nitriles, as useful intermediates for the synthesis of substituted pyrimidines and cyclopentenones.
abstract: A new approach to the synthesis of pyrimidines and cyclopentenones is described. The method exploits the reactivity of alpha,beta-unsaturated acetals with aromatic nitriles in the presence of the Schlosser's superbase LIC-KOR.
authors: Dipartimento di Chimica Generale e Chimica Organica, Università di Torino, Via P. Giuria, 7, I-10125 Torino, Italy.
authors: Marco
authors: M
authors: Blangetti
authors: Annamaria
authors: A
authors: Deagostino
authors: Cristina
authors: C
authors: Prandi
authors: Chiara
authors: C
authors: Zavattaro
authors: Paolo
authors: P
authors: Venturello
mesh_terms: D000080:Acetals / Q000737:chemistry*; D002073:Butanes / Q000737:chemistry*; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D005019:Ethyl Ethers / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011188:Potassium / Q000737:chemistry*; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C529985:1,1-diethoxybut-2-ene; D000080:Acetals; D002073:Butanes; D003517:Cyclopentanes; D005019:Ethyl Ethers; D007097:Imines; D009570:Nitriles; D011743:Pyrimidines; D008094:Lithium; C013905:cyclopentenone; D011188:Potassium