title: Factitious increases in serum testosterone concentrations related to phenylbutazone therapy.
abstract: We report 6 additional observations of a drug/hormone assay interaction between serum testosterone and phenylbutazone intake. This interaction had been described previously only once. We discuss its potential mechanisms, based upon our experimental findings, and its clinical implications.
authors: Department of Pharmacology, AP-HP, hôpital Avicenne, 125 route de Stalingrad, 93009-Bobigny, and Paris-XIII University, France. bernard.uzzan@avc.aphp.fr
authors: Bernard
authors: B
authors: Uzzan
authors: Dominique
authors: D
authors: Dumont-Fischer
authors: Najiba
authors: N
authors: Lahlou
authors: Hélène
authors: H
authors: Bihan
authors: Marie-Christophe
authors: MC
authors: Boissier
authors: Jean-Claude
authors: JC
authors: Alvarez
authors: Gérard-Yves
authors: GY
authors: Perret
authors: Régis
authors: R
authors: Cohen
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000009:adverse effects* / Q000627:therapeutic use; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013739:Testosterone; D010653:Phenylbutazone