title: [Anxious depressive conditions in patients with gastroesophageal reflux disease].
abstract: The authors objectively evaluated the presence of anxious depressive conditions in patients with gastroesophageal reflux disease (GERD) and studied associations between them and the clinical picture of the disease. Ninety-one patients with GERD were examined. The diagnosis was based on clinical and anamnestic data as well as the results of esophagogastroduodenoscopy and rabeprazole test. Gastrointestinal Symptom Rating Scale (GSRS) was used to assess the severity of GERD symptoms and quality of life. Beck Scale was applied to assess the level of depression. Spielberg test was used to assess reactive and personal anxiety. The psychological status of GERD patients was studied before the beginning of the treatment. Tests and questionnaires were filled by patients on their own. Spielberg test and Beck Scale revealed a high prevalence of psychopathic syndromes among GERD patients. Forty-three per cent of patients had anxious syndrome, while 57% of patients suffered from anxious depressive syndrome; the anxiety level and depression level were clinically significant in 70% of cases and in 23%, respectively. The presence of a direct correlation between the severity of the psychopathological syndromes (according to Spielberg test and Beck Scale) and GSRS data demonstrate that anxiety and depression intensify GERD symptoms and lower the quality of life of these patients. There is no doubt that concomitant anxious and anxious-depressive disturbances need psychotherapeutic and drug correction. Tranquilizers have the priority in neurotic anxious disturbances. In some situations antidepressants are indicated to treat a combination of anxious disturbances and depressive ones.
authors: N S
authors: NS
authors: Lapina
authors: N N
authors: NN
authors: Borovkov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology / Q000209:etiology* / Q000523:psychology; D003863:Depression / Q000453:epidemiology / Q000209:etiology* / Q000523:psychology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology