title: Semantics-enabled service discovery framework in the SIMDAT pharma grid.
abstract: We present the design and implementation of a semantics-enabled service discovery framework in the data Grids for process and product development using numerical simulation and knowledge discovery (SIMDAT) Pharma Grid, an industry-oriented Grid environment for integrating thousands of Grid-enabled biological data services and analysis services. The framework consists of three major components: the Web ontology language (OWL)-description logic (DL)-based biological domain ontology, OWL Web service ontology (OWL-S)-based service annotation, and semantic matchmaker based on the ontology reasoning. Built upon the framework, workflow technologies are extensively exploited in the SIMDAT to assist biologists in (semi)automatically performing in silico experiments. We present a typical usage scenario through the case study of a biological workflow: IXodus.
authors: IT Research Division, NEC Laboratories, Europe, NEC Europe Ltd., D-53757 Sankt Augustin, Germany. qu@it.neclab.edu
authors: Cangtao
authors: C
authors: Qu
authors: Falk
authors: F
authors: Zimmermann
authors: Kai
authors: K
authors: Kumpf
authors: Richard
authors: R
authors: Kamuzinzi
authors: Valérie
authors: V
authors: Ledent
authors: Robert
authors: R
authors: Herzog
mesh_terms: D003299:Cooperative Behavior; D003628:Database Management Systems; D016503:Drug Delivery Systems / Q000379:methods*; D015195:Drug Design; D033181:Information Dissemination / Q000379:methods; D020407:Internet; D009323:Natural Language Processing; D025941:Protein Interaction Mapping / Q000379:methods*; D012660:Semantics