Diels-alder reaction of 2(1H)-pyridones acting as dienes.
Diels-Alder reactions between N-phenylmaleimide, acting as the dienophile, and 2(1H)-pyridones having a methoxy or a chloro substituent, were carried out, under atmospheric and high pressure conditions, to give the corresponding isoquinuclidine derivatives. Stereoselectivity of the Diels-Alder reactions was studied using molecular orbital calculations.
Hoshino
Masato
M
Tohoku Pharmaceutical University, Sendai, Japan.
Matsuzaki
Hisao
H
Fujita
Reiko
R
D009682:Magnetic Resonance Spectroscopy; D008301:Maleimides / Q000737:chemistry*; D008958:Models, Molecular; D011725:Pyridines / Q000737:chemistry*; D011812:Quinuclidines / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
D008301:Maleimides; D011725:Pyridines; D011812:Quinuclidines; C028525:N-phenylmaleimide