Critical condition for the occurrence of a noise-reduction effect.
Based on a copy number control model of bacterial plasmid, the internal noise near a given steady state is investigated by using the linear noise approximation. All the parameters are restricted to a certain region so that the time spent near the steady state is long enough and the absorbing state can be neglected. For the noise in the plasmid molecules, a transition occurs with increasing the noise in the signal molecules under certain conditions. A noise-reduction mechanism, noise suppression by noise, is found. More importantly, the critical condition for the occurrence of the noise-reduction effect is given in our theoretical treatment.
Yi
Ming
M
Department of Physics and Institute of Biophysics, Central China Normal University, Wuhan, China.
Jia
Ya
Y
Ma
Jun
J
Tang
Jun
J
Yu
Guang
G
Li
Jiarong
J
D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000378:metabolism*; D003198:Computer Simulation; D005246:Feedback / Q000502:physiology; D018628:Gene Dosage / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D008954:Models, Biological; D015233:Models, Statistical
D001426:Bacterial Proteins