A biaryl xanthone derivative having axial chirality from Penicillium vinaceum.
A new xanthone derivative having axial chirality was isolated from Penicillium vinaceum. Owing to the axial chirality, its structure, including absolute configuration, was determined by means of extensive spectroscopic data, such as UV, IR, MS, and 1D and 2D NMR spectra, and computational chiroptical methods. The new compound, (a R)-2'-methoxyvinaxanthone, has a structure containing two aromatic moieties with substituents hindering rotation about the biaryl axis. The compound gave positive results in a sea urchin egg test ( Paracentrotus lividus) and a crown gall tumor on potato disks test (Agrobacterium tumefaciens).
Rezanka
Tomás
T
Institute of Microbiology, Prague, Czech Republic. rezanka@biomed.cas.cz
Rezanka
Pavel
P
Sigler
Karel
K
D000818:Animals; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010063:Ovum / Q000187:drug effects / Q000254:growth & development; D010407:Penicillium / Q000737:chemistry*; D010941:Plant Tumors; D012617:Sea Urchins / Q000187:drug effects / Q000254:growth & development; D011198:Solanum tuberosum / Q000187:drug effects; D044004:Xanthones / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology
C530230:(aR)-2'-methoxyvinaxanthone; D044004:Xanthones