title: [Synthesis of polyamine-containing oligonucleotides].
abstract: A simple and efficient method of synthesis of polyamine-oligonucleotide conjugates in high yields (up to 95%) was suggested. The terminal phosphate group of deprotected oligonucleotides was selectively activated with the redox pair triphenylphosphine-dipyridyl disulfide in the presence of a nucleophilic catalyst, and the activated oligonucleotide derivative was subjected to the reaction with a polyamine.
authors: A S
authors: AS
authors: Levina
authors: E A
authors: EA
authors: Mikhaleva
authors: M N
authors: MN
authors: Repkova
authors: V F
authors: VF
authors: Zarytova
mesh_terms: D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D011073:Polyamines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D009841:Oligonucleotides; D011073:Polyamines