Amyloid-beta-related angiitis: a rare cause of recurrent transient neurological symptoms.
BACKGROUND
A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy.


METHODS
Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy.


METHODS
Amyloid-beta-related angiitis.


RESULTS
The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.
Amick
Amy
A
Beth Israel Deaconess Medical Center, Department of Neurology, Boston, MA 02215, USA. aamick@bidmc.harvard.edu
Joseph
Jeff
J
Silvestri
Nicholas
N
Selim
Magdy
M
D000368:Aged; D016229:Amyloid beta-Peptides / Q000009:adverse effects / Q000032:analysis; D002543:Cerebral Hemorrhage / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009422:Nervous System Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D012008:Recurrence; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology
D016229:Amyloid beta-Peptides