The treatment of acute interstitial nephritis: More data at last.
Acute interstitial nephritis (AIN) is an uncommon form of acute renal failure that is usually medication related. Although the clinical features and renal histopathology are well recognized, therapy beyond discontinuing the offending drug has been a challenge. The use of corticosteroids, although supported by numerous small retrospective studies and anecdotal case reports, has been controversial. The study by González et al., although it has limitations, provides solid support for the early use of corticosteroids in the treatment of drug-related AIN.
Appel
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GB
Columbia University College of Physicians and Surgeons, New York, New York, USA. gba2@columbia.edu
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D006801:Humans; D009395:Nephritis, Interstitial / Q000139:chemically induced / Q000188:drug therapy*
D000305:Adrenal Cortex Hormones