[Role of contrast-enhanced ultrasound in the differentiation of solid focal lesions of pancreas].
OBJECTIVE
To investigate the value of contrast-enhanced ultrasound in the differential diagnosis of solid focal lesions of pancreas (s-FLPs).


METHODS
We retrospectively analyzed the clinical data of 56 s-FLPs examined with contrast agent combined with low mechanical indicators contrast-enhanced ultrasound.


RESULTS
The surrounding pancreas parenchyma enhancement time, lesion enhancement time, and peak enhancement time between different groups of s-FLPs had no significant differences (P > 0.05), while the beginning to peak enhancement time showed significant difference (P < 0.05). When using the enhancement speed as a diagnostic indicator to differentiate pancreatic carcinoma from tumor-like pancreatitis, the sensitivity, specificity, and accuracy were 90.5%, 71.4%, and 85.7% for pancreatic carcinoma and 75.0%, 91.7%, and 89.3% for tumor-like pancreatitis. When using the enhancement pattern as a diagnosis indicator to differentiate pancreatic carcinoma from tumor-like pancreatitis, the sensitivity, specificity, and accuracy were 85.7%, 78.6%, and 83.9% for pancreatic carcinoma and 75.0%, 100%, and 94.6% for tumor-like pancreatitis. When different indicators were combined, enhancement pattern and enhancement speed showed the best diagnostic results; however, the Youden index was not improved.


CONCLUSIONS
Different s-FLPs show different enhancement findings on contrast-enhanced ultrasound. The enhancement pattern and enhancement speed are the most useful diagnostic indicators.
Xie
Xiao-Yan
XY
Department of Ultrasound, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Xu
Er-Jiao
EJ
Xu
Hui-Xiong
HX
Xu
Zuo-Feng
ZF
Liu
Guang-Jian
GJ
Zheng
Yan-Ling
YL
Liang
Jin-Yu
JY
Huang
Bei
B
Lü
Ming-De
MD
D003937:Diagnosis, Differential; D006801:Humans; D010179:Pancreas / Q000000981:diagnostic imaging*; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging*; D010195:Pancreatitis / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014463:Ultrasonography