Rhabdomyolysis and acute myoglobinuric renal failure in a patient with bilateral pheochromocytoma following open pyelolithotomy.
Rhabdomyolysis is an unusual manifestation of pheochromocytoma. Early diagnosis and prompt management are crucial, as it may have life-threatening consequences. This is the case of a 19-year-old man with bilateral pheochromocytoma complicated with rhabdomyolysis and acute myoglobinuric renal failure after surgery for nephrolithiasis. A massive catecholamine release during the procedure manifested itself as a hypertensive crisis, producing severe vasoconstriction and thereby provoking ischemia of the patient's muscle tissue. This insult resulted in rhabdomyolysis and acute myoglobinuric renal failure. After making sure that all necessary medical precautions were performed, including blood pressure stabilization with alpha receptor blockade and adequate fluid replacement, the patient successfully underwent a bilateral cortex-sparing medullar adrenalectomy. The operation specimen was reported as pheochromocytoma.
Anaforoglu
Inan
I
Division of Endocrinology and Metabolism, Department of General Surgery, Baskent University Faculty of Medicine, 06490-Ankara, Turkey. ianaforoglu@hotmail.com
Ertorer
M Eda
ME
Haydardedeoglu
Filiz E
FE
Colakoglu
Tamer
T
Tokmak
Naime
N
Demirag
Nilgun G
NG
D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D000328:Adult; D006801:Humans; D008297:Male; D009212:Myoglobinuria / Q000175:diagnosis / Q000209:etiology*; D053040:Nephrolithiasis / Q000601:surgery; D010673:Pheochromocytoma / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D012206:Rhabdomyolysis / Q000150:complications*