Electron density controlled carbamate ligand binding mode: towards a better understanding of metalloenzyme activity.
The first structurally characterized mononuclear biscarbamate complex of Zn with eta1-coordinated carbamate ligands can be prepared by reaction between [EtZn(O2CN(iBu)2)]4 and a guanidine base. Usage of a weaker base leads to eta2-coordinated complexes.
Neuhäuser
C
C
Anorganisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, D-69120, Heidelberg, Germany.
Domide
D
D
Mautz
J
J
Kaifer
E
E
Himmel
H-J
HJ
D001665:Binding Sites; D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D004583:Electrons; D004789:Enzyme Activation; D019791:Guanidine / Q000737:chemistry; D008024:Ligands; D008667:Metalloproteins / Q000737:chemistry*; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D044345:Phosphoric Triester Hydrolases / Q000737:chemistry*; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
D002219:Carbamates; D008024:Ligands; D008667:Metalloproteins; D009942:Organometallic Compounds; D044345:Phosphoric Triester Hydrolases; D015032:Zinc; D019791:Guanidine