Enhancement of disease resistance to Magnaporthe grisea in rice by accumulation of hydroxy linoleic acid.
Linoleic acid (18:2) and linolenic acid (18:3) are sources for various oxidized metabolites called oxylipins, some of which inhibit growth of fungal pathogens. In a previous study, we found disease resistance to rice blast fungus Magnaporthe grisea enhanced in 18:2-accumulating transgenic rice (F78Ri) in which the conversion from 18:2 to 18:3 was suppressed. Here, we demonstrate that 18:2-derived hydroperoxides and hydroxides (HPODEs and HODEs, respectively) inhibit growth of M. grisea more strongly than their 18:3-derived counterparts. Furthermore, in F78Ri plants, the endogenous levels of HPODEs and HODEs increased significantly, compared with wild-type plants. These results suggest that the increased accumulation of antifungal oxylipins, such as HPODEs and HODEs, causes the enhancement of disease resistance against M. grisea.
Yara
Asanori
A
Department of Biology, Faculty of Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.
Yaeno
Takashi
T
Montillet
Jean-Luc
JL
Hasegawa
Morifumi
M
Seo
Shigemi
S
Kusumi
Kensuke
K
Iba
Koh
K
D006878:Hydroxides / Q000378:metabolism / Q000494:pharmacology; D019787:Linoleic Acid / Q000378:metabolism*; D008042:Linolenic Acids / Q000235:genetics; D008054:Lipid Peroxides / Q000378:metabolism / Q000494:pharmacology; D020082:Magnaporthe / Q000187:drug effects / Q000502:physiology; D012275:Oryza / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology*; D054883:Oxylipins / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology*; D010936:Plant Extracts / Q000494:pharmacology; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism / Q000382:microbiology; D013172:Spores, Fungal / Q000187:drug effects
D006878:Hydroxides; D008042:Linolenic Acids; D008054:Lipid Peroxides; D054883:Oxylipins; D010936:Plant Extracts; D019787:Linoleic Acid