Translational research in breast cancer.
The discovery of 25,000 human genes from the Human Genome Project has had a dramatic impact on the translational landscape of human diseases. Nowhere is the impact more apparent than in the field of cancer, specifically breast cancer. Understanding of the malignant process at a molecular level, coupled with the discovery of novel molecular techniques, has shifted the paradigm of treating breast cancer from a clinical, population-based risk assessment model to one based on molecular classification of disease.
Chu
Quyen D
QD
Department of Surgery, Louisiana State University Health Sciences Center-Shreveport, The Feist-Weiller Cancer Center, 1501 Kings Highway, P.O. Box 33932, Shreveport, LA 71130-3932, USA. qchu@lsuhsc.edu
Holm
Neal
N
Byrnes
Kerry
K
Li
Benjamin D
BD
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000378:metabolism / Q000601:surgery; D019317:Evidence-Based Medicine; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D011379:Prognosis; D040901:Proteomics
D000970:Antineoplastic Agents