Resistance determinant erm(X) is borne by transposon Tn5432 in Bifidobacterium thermophilum and Bifidobacterium animalis subsp. lactis.
The erm(X) gene from erythromycin- and clindamycin-resistant Bifidobacterium strains was characterised by polymerase chain reaction and sequence analysis, including flanking regions. Results suggest that the resistance determinant was part of transposon Tn5432 that has been described in several opportunistic pathogens such as Corynebacterium striatum and Propionibacterium acnes.
van Hoek
Angela H A M
AH
RIKILT-Institute of Food Safety, Wageningen UR, Bornsesteeg 45, NL-6708PD Wageningen, The Netherlands. angela.vanhoek@wur.nl
Mayrhofer
Sigrid
S
Domig
Konrad J
KJ
Aarts
Henk J M
HJ
D000818:Animals; D001644:Bifidobacterium / Q000187:drug effects / Q000235:genetics*; D017931:DNA Primers; D004251:DNA Transposable Elements / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005243:Feces / Q000382:microbiology; D005798:Genes, Bacterial / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013552:Swine
D017931:DNA Primers; D004251:DNA Transposable Elements; D004269:DNA, Bacterial