title: [Rendu-Osler-Weber disease as an infrequent cause of stroke].
abstract: BACKGROUND
  Hereditary haemorrhagic telangiectasia, or Rendu-Osler disease, is a congenital vascular disease that is associated with the presence of arteriovenous fistulas that cause paradoxical embolisms.
  
  
  METHODS
  An 83-year-old female with clinical signs and symptoms of convulsive attacks and multiple cerebral infarctions in the acute phase. She also presented a history of multiple haemorrhages and iron deficiency anaemia with no clear aetiological causation. A thorough examination of her medical history revealed a family history of haemorrhages and a sister who had been diagnosed with Rendu-Osler disease, which suggested the possible existence of a pulmonary arteriovenous fistula as the aetiological causation of her cerebrovascular disease. Neurovascular Doppler ultrasonography with bubble contrast test was positive, and the presence of the fistula was confirmed by a computerised axial tomographic angiography scan of the lungs.
  
  
  CONCLUSIONS
  Rendu-Osler disease is a rare cause of stroke due to the fact that it is usually associated with arteriovenous fistulas that can cause paradoxical embolisms. Neurovascular Doppler ultrasound scanning is useful for detecting these pulmonary fistulas by means of the bubble contrast test, which is a non-invasive test that can be carried out easily by neurologists themselves.
authors: Unidad de Neurología, Hospital Marina Alta, Denia, Alicante, España. gemmasese@hotmail.com
authors: G
authors: G
authors: Más-Sesé
authors: D
authors: D
authors: Sola-Martínez
authors: M A
authors: MA
authors: García-Quesada
authors: I
authors: I
authors: Riba-Llena
authors: R
authors: R
authors: Hurtado
authors: N
authors: N
authors: López-Hernández
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D020521:Stroke / Q000209:etiology*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*