Short radius intermittent centrifugation as a countermeasure to bed-rest and 0-G deconditioning: IMAG pilot study summary and recommendations for research.
Head down bed-rest for 21 days was used as a ground analog of space flight in a pilot study to assess the pros and cons of daily 1 hr short radius centrifugation as a flight countermeasure. Positive results were found for cardiovascular and muscle protection, effectiveness was indicated for bone protection, and no negative issues interfering with high speed centrifugation were uncovered. The directions for extension of artificial gravity (AG) research to make it practical for extended space voyages are presented.
Young
Laurence R
LR
Massachusetts Institute of Technology, Man-Vehicle Lab, 37-219, Cambridge, MA 02139, USA. lry@mit.edu
Paloski
William H
WH
D001510:Bed Rest / Q000009:adverse effects*; D001847:Bone Diseases / Q000209:etiology / Q000517:prevention & control; D018493:Cardiovascular Deconditioning; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D002498:Centrifugation; D018470:Gravity, Altered; D006801:Humans; D008297:Male; D009135:Muscular Diseases / Q000209:etiology / Q000517:prevention & control; D010865:Pilot Projects; D012107:Research Design; D013026:Space Flight; D013997:Time Factors; D014481:United States; D018557:United States National Aeronautics and Space Administration; D018544:Weightlessness Countermeasures; D018474:Weightlessness Simulation