title: The clinical effect of gender on outcome of total knee arthroplasty.
abstract: The purpose of this study was to quantify the effect of sex on the clinical outcome and survivorship of a total knee arthroplasty (TKA) with clinical and radiographic follow-up. Seven thousand three hundred twenty-six primary AGC (Biomet, Warsaw, Ind) cruciate-retaining TKAs were performed from 1987 to 2004. Of these, 59.5% were performed on women. We examined preoperative and postoperative Knee Society knee score, function scores, pain scores, walking ability, stair-climbing ability, flexion, and implant survivorship based on sex. Female sex was associated with lower overall preoperative clinical scores for all parameters (P < .01). Improvement in Knee Society knee score and flexion was greater for women (P = .006), and there were equal pain relief and walking improvements for both sexes (P < .32). Stair and function score improvements were greater for men (P = .002). Implant survival was 98% for women and men at 15 years (P = .4684). We conclude that improvement after TKA is similar for men and women, with few clinically significant differences. Sex-specific implants would appear to offer no clinical advantage.
authors: The Center for Hip and Knee Surgery, St Francis Hospital, Mooresville, Mooresville, IN 46158, USA.
authors: Merrill A
authors: MA
authors: Ritter
authors: Jennifer T
authors: JT
authors: Wing
authors: Michael E
authors: ME
authors: Berend
authors: Kenneth E
authors: KE
authors: Davis
authors: John B
authors: JB
authors: Meding
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D011475:Prosthesis Failure; D012737:Sex Factors; D016019:Survival Analysis; D016896:Treatment Outcome