Childhood hypersensitivity pneumonitis associated with fungal contamination of indoor hydroponics.
Childhood hypersensitivity pneumonitis (HP) is often associated with exposure to antigens in the home environment. We describe a case of HP associated with indoor hydroponics in a 14-year-old girl. Water samples from hydroponics revealed Aureobasidium pullulans as the dominant fungal micro-organism (10(4)CFU/ml). The diagnosis is supported by the existence of serum precipitating antibodies against A. pullulans, lymphocytic alveolitis on bronchoalveolar lavage (BAL) fluid, a corresponding reaction on a lung biopsy, and the sustained absence of clinical symptoms following the removal of hydroponics from the home. We conclude that hydroponics should be considered as potential sources of fungal contaminants when checking for indoor health complaints.
Engelhart
Steffen
S
Institut für Hygiene und Offentliche Gesundheit, Universität Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. steffen.engelhart@ukb.uni-bonn.de
Rietschel
Ernst
E
Exner
Martin
M
Lange
Lars
L
D000293:Adolescent; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000382:microbiology*; D000908:Antibodies, Fungal / Q000097:blood; D000946:Antigens, Fungal / Q000276:immunology*; D001487:Basidiomycota / Q000276:immunology / Q000302:isolation & purification; D001706:Biopsy; D018893:Bronchoalveolar Lavage / Q000379:methods; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006798:Housing; D006801:Humans; D018527:Hydroponics; D008168:Lung / Q000503:physiopathology
D000908:Antibodies, Fungal; D000946:Antigens, Fungal