title: The age incidence of childhood B-cell precursor acute lymphoblastic leukemia in Mexico City.
abstract: The objective of this population-based survey was to assess the peak age of incidence of B-cell precursor acute lymphoblastic leukemia (ALL) in children in Mexico City (MC). All patients were classified according to their immunophenotype, and only B-cell precursor and T-lineage were analyzed. Rates of incidence were calculated x10 children. Of the 364 children from MC who were included in this study, immunophenotyping had been performed for 81.6%. The frequency of B-cell precursor ALL was 76.1%, whereas T lineage ALL showed a frequency of 23.6%. Peak age for ALL was 2 to 3 years of age. B-cell precursor ALL was the major contributor to peak age; T lineage ALL showed a peak among 1 and 3 years of age. We conclude that the age peak for children with ALL in MC is within the ranges reported for developed countries and that B-cell precursor ALL is the main contributor to these peak.
authors: Hematology, Pediatric Hospital, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
authors: Roberto
authors: R
authors: Bernaldez-Rios
authors: Manuel C
authors: MC
authors: Ortega-Alvarez
authors: Maria L
authors: ML
authors: Perez-Saldivar
authors: Norma E
authors: NE
authors: Alatoma-Medina
authors: Maria de Los A
authors: Mde L
authors: Del Campo-Martinez
authors: Maria Del Carmen
authors: Mdel C
authors: Rodriguez-Zepeda
authors: Ines
authors: I
authors: Montero-Ponce
authors: Sergio
authors: S
authors: Franco-Ornelas
authors: Gabriela
authors: G
authors: Fernandez-Castillo
authors: Nora N
authors: NN
authors: Nuñez-Villegas
authors: Miguel A
authors: MA
authors: Taboada-Flores
authors: Janet
authors: J
authors: Flores-Lujano
authors: Muriel E
authors: ME
authors: Argüelles-Sanchez
authors: Servando
authors: S
authors: Juarez-Ocaña
authors: Arturo
authors: A
authors: Fajardo-Gutierrez
authors: Juan Manuel
authors: JM
authors: Mejia-Arangure
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008800:Mexico / Q000453:epidemiology; D011153:Population; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000453:epidemiology*; D016019:Survival Analysis