Graft loss in three patients with donor-specific antibody (DSA).
1. All patients had donor-specific antibodies and lost their transplant. 2. Flow PRA did not correlate with the transplant dysfunction. 3. In GT the DSA monitored could be used to monitor the effectiveness of the plasmapheresis. 4. DSA was strongly associated with transplant dysfunction and graft loss.
Qasi
Y
Y
Department of Medicine and Metic Transplantation Lab, USC Keck School of Medicine.
Hermes
M
M
Cicciarelli
J
J
D000961:Antilymphocyte Serum / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007518:Isoantibodies / Q000097:blood*; D016030:Kidney Transplantation / Q000276:immunology*; D016031:Liver Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D017211:Treatment Failure
D000961:Antilymphocyte Serum; D007155:Immunologic Factors; D007518:Isoantibodies