HPV-related anogenital disease and HIV infection: not always 'ordinary' condylomata acuminata.
Human papillomavirus (HPV) is responsible for various diseases in the anogenital region which range from benign condylomata acuminata to anal carcinoma. Buschke-Loewenstein tumour is a clinically 'intermediate' condition which is histologically benign but due to extensive destruction of the local tissues can show malignant behaviour. Its early recognition as a different clinical entity to 'ordinary' condylomata acuminata is important for its adequate management. Immunocompromised persons, such as those with HIV infection, have a higher incidence of HPV-related anogenital disease. Different aspects of the HPV-related anogenital disease in HIV-positive individuals are discussed.
Mudrikova
T
T
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Heidelberglaan 100 Utrecht 3584 CX, the Netherlands.
Jaspers
C
C
Ellerbroek
P
P
Hoepelman
A
A
D052685:Alphapapillomavirus; D001005:Anus Neoplasms / Q000821:virology*; D003218:Condylomata Acuminata / Q000175:diagnosis / Q000821:virology; D005260:Female; D005833:Genital Neoplasms, Female / Q000821:virology*; D005834:Genital Neoplasms, Male / Q000821:virology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications*; D011230:Precancerous Conditions / Q000821:virology*; D011379:Prognosis; D012307:Risk Factors; D012878:Skin Neoplasms / Q000821:virology*; D014412:Tumor Virus Infections / Q000150:complications*