Gold nanoparticles and oxidative stress in Mytilus edulis.
Little is known about potential environmental impact of nanoparticles. Gold nanoparticles can cause unexpected biological responses. Here, Mytilus edulis were exposed (24h) to gold-citrate nanoparticles (GNP), menadione and both compounds simultaneously (GNP/menadione). Protein ubiquitination and carbonylation were determined in gill, mantle and digestive gland, along with traditional oxidative stress biomarkers; catalase activity and neutral red retention time assay (haemolymph). 2DE gels were performed on gill proteins (menadione; GNP/menadione). Our results reveal that GNP may induce oxidative stress.
Tedesco
S
S
Proteomics Research Group, Department of Biochemistry, Environmental Research Institute, University College Cork, Cork, Ireland.
Doyle
H
H
Redmond
G
G
Sheehan
D
D
D000818:Animals; D005880:Gills / Q000187:drug effects; D006046:Gold / Q000633:toxicity*; D053768:Metal Nanoparticles / Q000633:toxicity*; D049880:Mytilus edulis / Q000187:drug effects* / Q000378:metabolism*; D018384:Oxidative Stress / Q000187:drug effects*; D024483:Vitamin K 3 / Q000633:toxicity
D024483:Vitamin K 3; D006046:Gold