Phenanthrene-fused boron-dipyrromethenes as bright long-wavelength fluorophores.
A new class of boron-dipyrromethene (BDP or BODIPY) dyes was obtained by phenanthrene fusion to the beta-pyrrole positions, absorbing in the wavelength range of important laser sources. Despite a 'propeller-like' distorted structure in the crystalline state, the chromophore absorbs (log epsilon > or = 5) and fluoresces (Phif > or = 0.8) strongly and can be easily turned into a fluorescence light-up probe. Incorporation into latex beads produces bright and photostable single-dye and Förster Resonance Energy Transfer (FRET) particles for microscopy applications.
Descalzo
Ana B
AB
BAM-Federal Institute for Materials Research and Testing, Division I.5, Richard-Willstätter-Strasse 11, Berlin, Germany.
Xu
Hai-Jun
HJ
Xue
Zhao-Li
ZL
Hoffmann
Katrin
K
Shen
Zhen
Z
Weller
Michael G
MG
You
Xiao-Zeng
XZ
Rurack
Knut
K
D001895:Boron / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018613:Microscopy, Confocal; D008958:Models, Molecular; D010616:Phenanthrenes / Q000737:chemistry*; D011162:Porphobilinogen / Q000031:analogs & derivatives* / Q000737:chemistry
D005456:Fluorescent Dyes; D010616:Phenanthrenes; C507544:dipyrromethene; C031181:phenanthrene; D011162:Porphobilinogen; D001895:Boron