Non-invasive pre-surgical investigation of a 10 year-old epileptic boy using simultaneous EEG-NIRS.
Near-infrared spectroscopy (NIRS) is a novel imaging technique of potential value in the pre-surgical investigation of patients with refractory epilepsy. We recorded simultaneously electrophysiology (EEG; Compumedics, USA) and near-infrared spectroscopy (NIRS; ISS, USA) to examine the localization of the ictal onset zone and assess language lateralization in a young epileptic boy (L.H., 10 years) as part of his pre-surgical evaluation. L.H. underwent a prolonged EEG-NIRS recording while electro-clinical and electrical seizures were recorded. Results were compared to those obtained with other pre-surgical techniques (SPECT, FDG-PET, EEG-fMRI and EEG-MEG) and showed good concordance for ictal onset zone localization. A second NIRS session without EEG was carried out in order to investigate language lateralization. For this purpose, the patient performed a categorical verbal-fluency task during NIRS recordings. Results showed left-hemisphere dominance for language function in this young boy. This case report illustrates that multi-channel EEG-NIRS has the potential to contribute favourably to pre-surgical investigation in young patients.
Gallagher
Anne
A
Centre de Recherche en Neuropsychologie et Cognition, Université de Montréal, Département de Psychologie, Centre-Ville, Montréal, Québec, H3C 3J7, Canada.
Lassonde
Maryse
M
Bastien
Danielle
D
Vannasing
Phetsamone
P
Lesage
Frédéric
F
Grova
Christophe
C
Bouthillier
Alain
A
Carmant
Lionel
L
Lepore
Franco
F
Béland
Renée
R
Nguyen
Dang Khoa
DK
D002648:Child; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000097:blood / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D011182:Postoperative Care; D019265:Spectroscopy, Near-Infrared / Q000379:methods*