title: Does N-cadherin regulate interaction of hematopoietic stem cells with their niches?
abstract: In this issue of Cell Stem Cell, Kiel et al. (2007) demonstrate that N-cadherin is not expressed on repopulating hematopoietic stem cells (HSCs) and that reduction of osteoblasts does not affect HSC frequency, suggesting that other molecular pathways may also modulate the interaction of HSCs with their niches.
authors: Howard Hughes Medical Institute, Weill Cornell Medical College, New York, NY 10021, USA.
authors: Andrea T
authors: AT
authors: Hooper
authors: Jason
authors: J
authors: Butler
authors: Isabelle
authors: I
authors: Petit
authors: Shahin
authors: S
authors: Rafii
mesh_terms: D000818:Animals; D015820:Cadherins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D002448:Cell Adhesion / Q000502:physiology; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000502:physiology*; D051379:Mice; D010006:Osteoblasts / Q000502:physiology
chemical_list: D015820:Cadherins