title: Endobronchial metastasis from prostate cancer.
abstract: We report a case of endobronchial metastasis from prostate adenocarcinoma. A patient with a history of prostate cancer under complete androgen blockade presented to the respiratory department complaining of dyspnea and dry coughing. Flexible bronchoscopy showed multiple polypoid lesions in the tracheobronchial tree and the immunohistochemical studies on the biopsy specimen determined the diagnosis. The patient was treated with paclitaxel, estramustine phosphate and carboplatine, and experienced symptoms suppression. To our knowledge, this is the first case of endobronchial metastasis of a patient with androgen refractory prostate cancer without any evidence of extrathoracic metastasis. The current report also emphasises the need for a multidisciplinary approach for cases of endobronchial metastases, with the collaboration of pneumologists, urologists, pathologists and oncologists.
authors: Respiratory Medicine Department, University Hospital of Larissa, Larissa, Greece.
authors: Irini
authors: I
authors: Gerogianni
authors: Stavros
authors: S
authors: Gravas
authors: Dimitrios
authors: D
authors: Papadopoulos
authors: Anastassios
authors: A
authors: Terzis
authors: Maria
authors: M
authors: Nakou
authors: Vassilios
authors: V
authors: Tzortzis
authors: Konstantinos
authors: K
authors: Gourgoulianis
authors: Michael D
authors: MD
authors: Melekos
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D001999:Bronchoscopy; D016190:Carboplatin / Q000008:administration & dosage; D004961:Estramustine / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D004961:Estramustine; D016190:Carboplatin; D017239:Paclitaxel