title: Ovarian follicular volume and follicular surface area are better indicators of follicular growth and maturation, respectively, than is follicular diameter.
abstract: Because ovarian follicular growth occurs in three dimensions, and because follicular maturation (increased E(2)) is a result of an increase in the three-dimensional follicular surface area where testosterone (E(2) precursor)-producing theca interna cells are located, the three-dimensional follicular volume and the three-dimensional follicular surface area describe the three-dimensional follicular growth and maturation, respectively, more accurately than does the two-dimensional follicular diameter alone. Therefore, we present a mathematical model that describes the relationship of the two-dimensional follicular diameter, the three-dimensional follicular volume, and the three-dimensional follicular surface area to the three-dimensional follicular growth and maturation.
authors: Florida Institute for Reproductive Sciences and Technologies, Weston, Florida 33326-3257, USA.
authors: Yalcin
authors: Y
authors: Yavas
authors: Minna R
authors: MR
authors: Selub
mesh_terms: D000818:Animals; D004967:Estrogens / Q000097:blood; D005260:Female; D005498:Follicular Phase / Q000502:physiology*; D006107:Granulosa Cells / Q000378:metabolism; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology; D008962:Models, Theoretical; D006080:Ovarian Follicle / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000254:growth & development*; D014463:Ultrasonography
chemical_list: D004967:Estrogens