title: Renal calculi complicating short-term furosemide therapy after congenital heart surgery.
abstract: BACKGROUND
  Renal calcification is a known complication of Furosemide therapy.
  
  
  METHODS
  We describe 3 children who were diagnosed with renal calculi, not nephrocalcinosis, following the use of Furosemide for 4 weeks. All the infants (24, 18, and 8 months) had successful repair/palliation of congenital heart disease. The dose of Furosemide was 1-2 mg/kg/day and the duration between starting treatment and development of hematuria was 4 weeks.
  
  
  RESULTS
  In all 3 patients renal ultrasound confirmed the presence of renal calculi with no nephrocalcinosis. On follow-up, hematuria improved after 3-4 months.
  
  
  CONCLUSIONS
  Renal calculi can complicate short-term Furosemide treatment in children after repair of congenital heart disease. Patients on Furosemide should be closely monitored by urine analysis and/or urine calcium/creatinine ratio for early detection of this complication.
authors: Sudan Heart Center, Khartoum, Sudan. sulafakhalid2000@yahoo.com
authors: Sulafa K M
authors: SK
authors: Ali
mesh_terms: D002675:Child, Preschool; D004232:Diuretics / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004326:Drinking; D005665:Furosemide / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006330:Heart Defects, Congenital / Q000601:surgery*; D006345:Heart Septal Defects, Ventricular / Q000601:surgery; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007223:Infant; D007669:Kidney Calculi / Q000139:chemically induced* / Q000150:complications / Q000000981:diagnostic imaging; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced*; D011666:Pulmonary Valve Stenosis / Q000601:surgery; D013771:Tetralogy of Fallot / Q000601:surgery; D018785:Tricuspid Atresia / Q000601:surgery; D014463:Ultrasonography
chemical_list: D004232:Diuretics; D005665:Furosemide