Role and clinical importance of Helicobacter pylori infection in hemodialysis patients.
Dyspepsia is an extrarenal symptom frequently found in hemodialysed patients; it is due to chronic renal failure, and uremic gastritis is a specific associated condition in chronic renal failure (CRF). On the other hand, in the general population, Helicobacter pylori infection is an important dyspepsia-related risk factor; its close connections with gastro-duodenal pathology are already known, above all the peptic disease in a really exclusive way. By observation of a dyalitic group of patients, opportunely matched with a no CRF group, we evaluated CRF-associated uremia and Helicobacter pylori infection which could eventually interact causing symptoms and lesions. A statistical analysis of obtained data allowed us to conclude that, although there is not, from an epidemiological view-point, a larger diffusion of Helicobacter pylori among dyalitic patients compared to general population, moreover the infection is uremia-synergic in causing gastro-duodenal symptoms and lesions. These findings, therefore, suggest systematically investigation a possible Helicobacter pylori infection in CRF patients and its relation to gastritis grading, and searching for probable active peptic lesions.
Gioè
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FP
Università degli Studi di Palermo, Cattedre di Semeiotica e Metodologia Chirurgica.
Cudia
B
B
Romano
Gi
G
Cocchiara
G
G
Li Vecchi
V
V
Gioè
M A
MA
Calì
C
C
Lo Coco
L
L
Li Vecchi
M
M
Romano
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003627:Data Interpretation, Statistical; D004415:Dyspepsia / Q000175:diagnosis / Q000209:etiology*; D004724:Endoscopy; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000453:epidemiology; D016480:Helicobacter pylori; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D006435:Renal Dialysis; D013997:Time Factors