title: Comparison of clinicopathological characteristics of curatively resected pancreatic head and body/tail ductal cancers.
abstract: Few studies exist comparing the clinicopathological features between resectable pancreatic head (Ph) and body/tail ductal cancer (Pbt). Eighty consecutive patients with resectable tumors (Ph-56, Pbt-24) were analyzed. Tumor size was the only significant difference in clinicopathological factors between Ph and Pbt (Ph<Pbt). Although the MSTs between Ph and Pbt were not significant different, the 1-year survival rate of Ph was significantly greater than that of Pbt (67.9% versus 41.7%; p = 0.028). There were no significantly differences of recurrent rates between Ph and Pbt for individual recurrent sites. In Ph, highly metastasized LN stations were No.13 (on the posterior aspect of the head of the pancreas) at 48.2%, No.17 (on the anterior surface of the head of the pancreas) at 21.4%, No.12 (in the hepatoduodenal ligament) at 10.7%, and No.14 (along the superior mesenteric artery) at 8.9%. In Pbt, No.11 LN station (along the splenic artery) was frequently metastasized (41.7%). Although the metastasized LN stations were different between Ph and Pbt by anatomical reason, biological malignant behaviors such as the LN metastasis rate, the overall survival, and the recurrent pattern were similar.
authors: Department of Surgical Oncology, Institute of Geriatrics and Medical Science, Osaka City University Graduate School of Medicine, Osaka, Japan. bunzo@med.osaka-cu.ac.jp
authors: B
authors: B
authors: Nakata
authors: N
authors: N
authors: Yamada
authors: R
authors: R
authors: Amano
authors: M
authors: M
authors: Tendo
authors: M
authors: M
authors: Inoue
authors: K
authors: K
authors: Sakurai
authors: K
authors: K
authors: Hirakawa
mesh_terms: D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D010179:Pancreas; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D015996:Survival Rate