title: Gross and histopathological characteristics of two lipomas and a neurofibrosarcoma detected in aquacultured southern bluefin tuna, Thunnus maccoyii (Castelnau), in South Australia.
abstract: Three visible lesions were examined from two specimens of southern bluefin tuna. The lesions were examined grossly and two were identified as lipomas, the third bore similarities to a schwannoma. Histopathology confirmed that two consisted of mature adipocytes consistent with a diagnosis of lipoma. The third lesion consisted of spindle cells in Antoni A and B patterns and was tentatively diagnosed as a malignant schwannoma. Immunohistochemistry identified both S100 and glial fibrillary acid protein expression within the lesion, which, together with the histopathological appearance, is consistent with a diagnosis of neurofibrosarcoma.
authors: Primary Industries and Resources South Australia, Aquaculture, Aquatic Animal Health Unit, Adelaide, SA, Australia. colin.johnston@maf.govt.nz
authors: C J
authors: CJ
authors: Johnston
authors: M R
authors: MR
authors: Deveney
authors: T
authors: T
authors: Bayly
authors: B F
authors: BF
authors: Nowak
mesh_terms: D000818:Animals; D000906:Antibodies / Q000378:metabolism; D001315:Australia; D005393:Fish Diseases / Q000378:metabolism / Q000473:pathology*; D005398:Fisheries; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D008067:Lipoma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D018319:Neurofibrosarcoma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D009418:S100 Proteins / Q000032:analysis; D014413:Tuna / Q000502:physiology*
chemical_list: D000906:Antibodies; D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins