Effect of fractional urea clearance on survival of hemodialysis patients in relation to gender.
Many studies have demonstrated the relationship between dialysis dose and survival. Global mortality is similar among men and women; however, the influence of dialysis dose in the survival could be more intensive between women. Therefore, we conduct an observational study to evaluate the gender-related impact of single pool Kt/V (spKt/V) on the survival of patients submitted to hemodialysis in a university hospital. We found that survival was lower in groups with spKt/V smaller than 1.2 than in those with Kt/V between 1.2 and 1.4. Among female patients, spKt/V smaller than 1.2 had a more adverse effect in survival than among men with a comparable Kt/V. Otherwise, among women, the dialysis dose had an impact in survival even with Kt/V greater than 1.4. Thus, fractional urea clearance more heavily influenced the survival of females than males in hemodialysis patients.
Ferreira
Juliana Cunha
JC
Department of Internal Medicine, Discipline of Nephrology of the Botucatu Medical School, UNESP, São Paulo, Brazil.
de Andrade
Luís Gustavo Modelli
LG
Barretti
Pasqual
P
Caramori
Jaqueline Costa Teixeira
JC
Balbi
André Luís
AL
Martin
Luis Cuadrado
LC
D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D006435:Renal Dialysis; D012737:Sex Factors; D014508:Urea / Q000032:analysis*
D014508:Urea