title: [Analysis of 993 cases of fetal malformations from 1999 to 2006].
abstract: OBJECTIVE
  To study the value of prenatal ultrasound in the diagnosis of fetal malformations.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 993 cases of neonates and induced babies with malformations who were labored in our hospital from January 1999 to October 2006.
  
  
  RESULTS
  The incidence rate of fetal malformation was 22.5 per thousand in our study group. The detection rate of prenatal ultrasound was 79.02% (1 062/1 344), among which the detection rate of the severe malformations (87.58%, 860/982) were significantly higher than that of the minor malformations (55.80%, 202/362) (P < 0.005). The false negative rate was high for the extremity malformations (39.46%) and facial malformations (31.91%), especially the acrosclerodermas, simple cleft palates, and ear deformities.
  
  
  CONCLUSIONS
  Prenatal ultrasound is sensitive for fetal severe malformations, while the detection rate is low for fetal minor malformations.
authors: Department of Ultrasound, Affiliated Shenzhen Maternity and Child Healthcare Hospital, Nanfang Medical University, Shenzhen, Guangdong 518028, China. lishengli63@126.com
authors: Sheng-Li
authors: SL
authors: Li
authors: Xiu-Lan
authors: XL
authors: Chen
authors: Shu-Yuan
authors: SY
authors: Ouyang
authors: Yuan
authors: Y
authors: Yao
authors: Bo
authors: B
authors: Gong
authors: Cong-Ying
authors: CY
authors: Chen
authors: Xiao-Dong
authors: XD
authors: Yang
authors: Zhi-Lian
authors: ZL
authors: Xiao
authors: Yu-Mei
authors: YM
authors: Liao
mesh_terms: D000013:Congenital Abnormalities / Q000000981:diagnostic imaging*; D005188:False Negative Reactions; D006801:Humans; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal