title: Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.
abstract: Nornicotine, a native component of tobacco and minor nicotine metabolite, was found to catalyze the chemoselective reduction of alpha,beta-unsaturated aldehydes under homogeneous aqueous conditions.
authors: Department of Chemistry, Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors: Andrew P
authors: AP
authors: Brogan
authors: Tobin J
authors: TJ
authors: Dickerson
authors: Kim D
authors: KD
authors: Janda
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D004121:Dimethyl Sulfoxide; D009243:NAD / Q000737:chemistry; D009538:Nicotine / Q000031:analogs & derivatives* / Q000737:chemistry; D010084:Oxidation-Reduction; D012996:Solutions; D014867:Water / Q000737:chemistry
chemical_list: D000447:Aldehydes; D012996:Solutions; D014867:Water; D009243:NAD; D009538:Nicotine; C005311:nornicotine; D004121:Dimethyl Sulfoxide