Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles.
Using a Cu(2+)-dependent DNA ligation DNAzyme, a colorimetric sensor for Cu2+ has been developed based on directed assembly of DNA-functionalized gold nanoparticles by the ligation product, and such ligation DNAzyme-based sensors are intrinsically more sensitive than cleavage DNAzyme systems due to the lack of background.
Liu
Juewen
J
Department of Chemistry, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Lu
Yi
Y
D015374:Biosensing Techniques; D003124:Colorimetry; D003300:Copper / Q000032:analysis*; D004247:DNA / Q000737:chemistry; D021881:DNA, Catalytic / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*
D021881:DNA, Catalytic; D006046:Gold; D003300:Copper; D004247:DNA