title: [Inflammatory response in elderly patients with bacteremia].
abstract: OBJECTIVE
  To evaluate inflammatory markers (C reactive protein [CRP], interleukina-1beta [IL-1beta], IL-6 and tumoral necrosis factor [TNF-alpha]) as predictors of bloodstream infection in elderly patients with systemic inflammatory response syndrome (SIRS).
  
  
  METHODS
  Blood cultures and markers were performed at admission and on day 4.
  
  
  RESULTS
  Eighty-two patients were included, 34% with positive blood cultures. TNF-alpha and IL-6 values at admission were higher in patients with positive blood cultures (84.5 vs. 28.5 pg/mL [P = .001] and 192.5 vs. 113, [P = .017], respectively). TNF-alpha values on day 4 were higher in patients with positive cultures (50.5 vs. 30; P = .017).
  
  
  CONCLUSIONS
  High TNF-alpha and IL-6 values at admission, and TNF-alpha values on day 4 correlated with bloodstream infection.
authors: Servicio de Infecciones, Hospital Clínico-IDIBAPS, Universidad de Barcelona, Barcelona, Spain.
authors: Luis
authors: L
authors: Martí
authors: Carlos
authors: C
authors: Cervera
authors: Xavier
authors: X
authors: Filella
authors: José Luis
authors: JL
authors: Marín
authors: Manel
authors: M
authors: Almela
authors: José M
authors: JM
authors: Gatell
authors: Asunción
authors: A
authors: Moreno
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000097:blood* / Q000150:complications; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood* / Q000150:complications; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein