Pseudotumor cerebri following tapered corticosteroid treatment in an 8-month-old infant.
The authors report on an 8-month-old infant with an orbital capillary hemangioma. The patient had been treated with high-dose corticosteroid therapy and had had a recent decrease in dose. The patient presented to the emergency department with increased irritability and bulging fontanelles. On lumbar puncture the opening pressure was > 55 cm H(2)O. Ophthalmological examination revealed interval development of papilledema. The child was treated with high-volume lumbar puncture, subsequent drainage of 10 ml of cerebrospinal fluid, resumption of the previous steroid dose, and acetazolomide therapy. The patient's symptoms resolved and follow-up ophthalmological examination revealed interval resolution of papilledema. The authors present the youngest reported case of pseudotumor development after corticosteroid tapering.
Ray
Wilson Z
WZ
Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Lee
Amy
A
Blackburn
Spiros L
SL
Lueder
Gregg T
GT
Leonard
Jeffrey R
JR
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D018324:Hemangioma, Capillary / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods; D009918:Orbital Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D010211:Papilledema / Q000139:chemically induced; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D013396:Suction
D000893:Anti-Inflammatory Agents