title: Thermal behavior of luciferase on nanofabricated hydrophilic Si surface.
abstract: The thermal behavior of luciferase on nanofabricated hydrophilic Si surface was investigated using molecular dynamics simulations. At high temperature, LUC_CHANGES (structural changes in the active site of luciferase) were smaller on the nanofabricated hydrophilic Si surface than on a non-nanofabricated hydrophilic Si surface, although LUC_CHANGES were slightly larger on the nanofabricated hydrophilic Si surface than on a non-nanofabricated hydrophobic Si surface. At room temperature, LUC_CHANGES were smaller on the nanofabricated hydrophilic Si surface than on a non-nanofabricated and wet-treated Si surface. Thus, nanofabricated hydrophilic Si surface would be preferable for practical applications.
authors: Tsuruoka National College of Technology, 104 Sawada, Inooka, Tsuruoka City,Yamagata 997-8511, Japan. nisiyama@asagi.waseda.jp
authors: Katsuhiko
authors: K
authors: Nishiyama
mesh_terms: D001665:Binding Sites; D003198:Computer Simulation; D006860:Hydrogen Bonding; D008156:Luciferases / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D053758:Nanoparticles; D036103:Nanotechnology; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties; D013696:Temperature
chemical_list: D012822:Silicon Dioxide; D008156:Luciferases