[The pathogenesis of erectile dysfunction in metabolic syndrome].
The aim of the study was to investigate the pathogenesis of erectile dysfunction (ED) in men with metabolic syndrome (MS). The subjects of the study were 385 men with ED and MS and 210 patients with organic ED (control group). The results of a complex clinical and andrological examination demonstrated that the fundamental pathogenetic factor of ED in patients with MS was the alteration of arterial blood circulation in the cavernosal tissue. The most valuable method in the diagnosis of this form of ED was ultrasonographic measurement of postocclusive changes in the diameters of cavernous arteries, reflecting local endothelial function. In addition, in a substantial portion of MS patients, hormonal and neurological disturbances were found, which also contributed to the pathogenesis of ED in this category of patients.
Mazo
E B
EB
Gamidov
S I
SI
Iremashvili
V V
VV
Gasanov
R V
RV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001341:Autonomic Nervous System / Q000503:physiopathology; D001783:Blood Flow Velocity; D018450:Disease Progression; D004576:Electromyography; D004730:Endothelium, Vascular / Q000503:physiopathology; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D010413:Penis / Q000098:blood supply / Q000294:innervation; D012189:Retrospective Studies; D012307:Risk Factors; D014664:Vasodilation / Q000502:physiology