title: Case of metagonimiasis complicated with multiple intracerebral hemorrhages and diabetes mellitus.
abstract: Metagonimiasis yokogawai is an unusual intestinal parasitic disease caused by metacercariae of Metagonimus yokogawai. The first clinical manifestations of this disease do not always correlate with gastrointestinal signs. A 61-year-old man with left hemiparesis and disorientation was admitted to our hospital because of atypical nonhypertensive multiple intracerebral hemorrhages, which were conservatively treated. The patient was discharged from our hospital after 2 months without any neurological deficits; however, he was readmitted owing to a body temperature higher than 38 degrees C for nearly 2 weeks. Examination of stool revealed eggs of M. yokogawai, and the body temperature returned to normal after administration of praziquantel. Furthermore, the control of the patient's diabetes mellitus (DM) markedly improved after the treatment, although the patient had had DM for more than 2 years. We conclude that DM is a chronic sign of metagonimiasis in carriers and that intracerebral hemorrhage might be an acute sign in the aggravated phase of the disease.
authors: Department of Neurosurgery, Yamada Hospital, Shizuoka, Japan. merrityamada@hotmail.co.jp
authors: Shoko Merrit
authors: SM
authors: Yamada
authors: Shokei
authors: S
authors: Yamada
authors: Hitomi
authors: H
authors: Takada
authors: Yayoi Carol
authors: YC
authors: Hoshiai
authors: Shotetsu
authors: S
authors: Yamada
mesh_terms: D000818:Animals; D002543:Cerebral Hemorrhage / Q000209:etiology*; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000209:etiology*; D006578:Heterophyidae / Q000302:isolation & purification; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D016896:Treatment Outcome; D014201:Trematode Infections / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology
chemical_list: D011223:Praziquantel