Cellular marker of myofiber activity for ankle flexor and extensor under conditions of rat hindlimb suspension.
We supposed that the triglyceride content might be used as a cellular marker of muscle fiber activity and for the first time analyzed the triglyceride content in the fast- and slow-twitch muscle fibers of m. soleus and m. tibialis anterior under conditions of 7-day rat hindlimb suspension. Although the hindlimb suspension led to decrease of triglyceride content in the fast-twitch fibers of m. soleus and slow-twitch fibers of m. tibialis anterior, these differences were not significant. In spite of this the obtained data do not contradict our initial hypothesis.
Fokina
N M
NM
RF SRC, Institute for Biomedical Problems of Russian Academy of Sciences, 76A, Khoroshevskoe shosse, 123007, Moscow, Russian Federation. ymnat@yandex.ru
Tavitova
M G
MG
Shenkman
B S
BS
D000818:Animals; D000842:Ankle; D015415:Biomarkers / Q000378:metabolism; D005240:Feasibility Studies; D019417:Hindlimb Suspension; D018656:Muscle Fibers, Fast-Twitch / Q000378:metabolism*; D018657:Muscle Fibers, Slow-Twitch / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014280:Triglycerides / Q000378:metabolism*
D015415:Biomarkers; D014280:Triglycerides