[Clinical study of 36 cases with adenoid cystic carcinoma of the maxillary sinus].
OBJECTIVE
To study the clinical characters, management and the prognosis of patients with adenoid cystic carcinoma of the maxillary sinus.


METHODS
The clinical data were analyzed retrospectively for 36 patients with adenoid cystic carcinoma of the maxillary sinus to evaluate the treatment results of different modalities. The contribution of every factors influencing on survival were also analyzed. Survival analysis was performed by life table method, comparison among/between groups was performed using log-rank test, and multivariate analysis was carried out using Cox proportional hazard model.


RESULTS
The 5-year survival rate was 58.33% in all patients, while they were only 75.0% and 42.9% in stage III and stage IV lesions respectively. The 5-year survival rate of 66.7% was obtained in patients who received surgery combined with radiotherapy,71.4% and 12.5% respectively in those treated by surgery and by radiotherapy alone. Multivariate analysis indicated that stage, treatment modality, and the tumour residues in the primary treatment were the predict factors for the prognosis.


CONCLUSIONS
Advanced adenoid cystic carcinoma should be treated by combined surgery and radiotherapy. Stage, treatment approach and short-term therapeutic response are the most important factors affecting the prognosis of the patients with adenoid cystic carcinoma of the maxillary sinus.
Liu
Tian-run
TR
Department of Head and Neck, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China. liuruntian_513@163.com
Chen
Fu-Jin
FJ
Yang
An-Kui
AK
Li
Qiu-Li
QL
Guo
Zhu-Ming
ZM
Zhang
Quan
Q
Zeng
Zong-Yuan
ZY
D000293:Adolescent; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D015996:Survival Rate; D055815:Young Adult