Topiramate associated hypohidrosis and hyperthermia.
Topiramate is a new antiepileptic drug, used for treatment of partial onset seizure and refractory seizures. Although it is well tolerated in children, some adverse effects including hypohidrosis and hyperthermia are reported. We present two children with epilepsy who were treated with topiramate and developed hypohidrosis and hyperthermia.
Incecik
Faruk
F
Cukurova University Medical Faculty, Department of Pediatric Neurology, Adana, Turkey. fincecik@yahoo.com
Hergüner
M Ozlem
MO
Altunbasak
Sakir
S
D000927:Anticonvulsants / Q000009:adverse effects*; D002256:Carbonic Anhydrases; D002648:Child; D002675:Child, Preschool; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007007:Hypohidrosis / Q000139:chemically induced*; D007035:Hypothermia / Q000139:chemically induced*; D008297:Male; D012307:Risk Factors; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose; D002256:Carbonic Anhydrases