[The effect of initial periodontal therapy on metabolic control in type 2 diabetes mellitus].
OBJECTIVE
To investigate the effect of periodontal initial therapy on metabolic control in type 2 diabetes mellitus patients with chronic periodontitis.


METHODS
Thirty type 2 diabetic patients with chronic periodontitis were selected as experimental group, 30 patients with chronic periodontitis were selected as control group. Their gingival index(GI), probing depth(PD), clinical attachment level(CAL), fasting plasma glucose(FPG), glycated hemoglobin A1c(HbA1c), total cholesterol(TC) and triglyceride(TG) were evaluated using SAS 6.12 software package for multiple linear regression analysis before treatment(as base) and 1, 3 month(s) after periodontal initial therapy.


RESULTS
In both two groups, a significant improvement of periodontal index was found after periodontal initial therapy (P<0.05). After therapy, TC, TG in diabetic patients showed no changes(P>0.05), and FPG, HbA1c in fairly-controlled diabetic patients were reduced significantly(P<0.05) whereas the well-controlled diabetic patients showed slight but insignificant decrease for these parameter(P>0.05).


CONCLUSIONS
The result of periodontal initial therapy in the type 2 diabetic patients with chronic periodontitis is significant in short time. It can reduce the level of FPG and HbA1c. Supported by National Key Science and Technology Project from "Tenth Five Year Plan" (Grant No.2004BA720A26).
Shen
Chi-Jing
CJ
Department of Periodontics, College of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China.
Yin
Yuan-Zheng
YZ
Shu
Rong
R
D001786:Blood Glucose; D055113:Chronic Periodontitis / Q000150:complications* / Q000628:therapy*; D003774:Dental Plaque Index; D012534:Dental Scaling; D003924:Diabetes Mellitus, Type 2; D006442:Glycated Hemoglobin; D006801:Humans; D010512:Periodontal Index
D001786:Blood Glucose; D006442:Glycated Hemoglobin