title: Three live-birth pregnancies in a woman with Williams syndrome.
abstract: OBJECTIVE
  Maternal Williams syndrome with their associated (cardiac) malformations is rarely encountered during pregnancy.
  
  
  METHODS
  We report on a patient with Williams syndrome who has had 3 live-birth pregnancies.
  
  
  RESULTS
  Several noncardiac, mainly fetal, complications need to be anticipated: premature labor, intrauterine growth restriction with subsequent small-for-gestational-age offspring, and recurrence of congenital heart disease or similar syndromes.
  
  
  CONCLUSIONS
  The present case report illustrates that multiple live-birth pregnancies are possible in women with Williams syndrome, and it advocates the need for regular multidisciplinary assessments prior to and during pregnancy.
authors: Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands.
authors: Karin
authors: K
authors: van der Tuuk
authors: Willem
authors: W
authors: Drenthen
authors: Philip
authors: P
authors: Moons
authors: Werner
authors: W
authors: Budts
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D050498:Live Birth; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D018980:Williams Syndrome / Q000503:physiopathology*