title: Clinical impact of a newly developed capsule endoscope: usefulness of a real-time image viewer for gastric transit abnormality.
abstract: BACKGROUND
  A new capsule endoscope has been developed by Olympus Medical Systems. The visualization and usefulness of its real-time image viewer for gastric transit abnormality were evaluated by using this new device.
  
  
  METHODS
  Thirty-seven consecutive patients were enrolled. In cases of gastric transit abnormality (gastric transit > 60 min, detected by the real-time viewer), intramuscular metoclopramide (10 mg) was administered. Diagnostic yield and gastric and small bowel transit times in ten patients receiving (group A) and 27 not receiving (group B) metoclopramide were analyzed.
  
  
  RESULTS
  Median gastric transit time was longer in group A than in group B (110 vs. 24 min; P < 0.0001). Conversely, median small bowel transit time was shorter in group A than in group B (270 vs. 347 min; P < 0.05). Further, small bowel transit was complete in 9/10 patients (90%) in group A, and in 23/27 patients (85%) in group B, but the difference was not significant. Overall diagnostic yield was 78% (29/37 patients), and there was no significant difference in the ratio of abnormal findings documented between group A (8/10, 80%) and group B (21/27, 78%) patients.
  
  
  CONCLUSIONS
  This new technology allowed clear image interpretation, and the real-time viewer was useful for detecting gastric transit abnormalities and determining a need for metoclopramide administration in patients undergoing capsule endoscopy.
authors: Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
authors: Haruhiko
authors: H
authors: Ogata
authors: Koichiro
authors: K
authors: Kumai
authors: Hiroyuki
authors: H
authors: Imaeda
authors: Koichi
authors: K
authors: Aiura
authors: Tadakazu
authors: T
authors: Hisamatsu
authors: Susumu
authors: S
authors: Okamoto
authors: Yasushi
authors: Y
authors: Iwao
authors: Yoshinori
authors: Y
authors: Sugino
authors: Masaki
authors: M
authors: Kitajima
authors: Toshifumi
authors: T
authors: Hibi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053705:Capsule Endoscopes; D053704:Capsule Endoscopy / Q000379:methods*; D018492:Dopamine Antagonists / Q000008:administration & dosage; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage; D008875:Middle Aged
chemical_list: D018492:Dopamine Antagonists; D008787:Metoclopramide