Cobalt-mediated regio- and stereoselective assembly of dienamides by hydroaminative alkyne coupling of alpha,omega-diynes.
In the presence of CpCo(C(2)H(4))(2), alpha,omega-diynes undergo hydroaminative coupling with amides to furnish new dienamides with control of regio- and stereochemistry.
Gandon
Vincent
V
Department of Chemistry, University of California at Berkeley, and the Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720-1460, USA.
Aubert
Corinne
C
Malacria
Max
M
Vollhardt
K Peter C
KP
D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D000586:Amination; D003035:Cobalt / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D000577:Amides; D009942:Organometallic Compounds; D003035:Cobalt