A stable, commercially available sulfenyl chloride for the activation of thioglycosides in conjunction with silver trifluoromethanesulfonate.
p-Nitrobenzenesulfenyl chloride is a stable commercially available sulfenyl chloride that, in conjunction with silver triflate, cleanly activates a wide range of thioglycosides for glycosylation at -78 degrees C in CH(2)Cl(2).
Crich
David
D
Department of Chemistry, Wayne State University, Detroit, MI 48202, USA. dcrich@chem.wayne.edu
Cai
Feng
F
Yang
Fan
F
D006031:Glycosylation; D008698:Mesylates / Q000737:chemistry*; D009578:Nitrobenzenes / Q000737:chemistry*; D013865:Thioglycosides / Q000737:chemistry*
C518227:4-nitrobenzenesulfonyl chloride; D008698:Mesylates; D009578:Nitrobenzenes; D013865:Thioglycosides; C012077:trifluoromethanesulfonic acid