title: Unilateral mydriasis due to Angel's trumpet.
abstract: BACKGROUND
  There are many causes of bilateral and unilateral mydriasis. Common garden plants, such as Brugmansia (Angel's trumpet), contain tropane alkaloids.
  
  
  METHODS
  An 11-year-old girl was brought to the Emergency Department because of discomfort and difficulty with near vision in the left eye, accompanied by unilateral mydriasis (pupil approximately 8 mm, unresponsive to both papillary light reflex and accommodation reflex). The consensual papillary light reflex of the right eye, the anterior chambers, the fundi, and the extraocular movements were intact. The history revealed that she had been playing in the garden and had just touched "a nice pink flower, similar to a trumpet." Treatment was symptomatic and supportive, and the anisocoria resolved 48 hours after exposure. Morphological and chemical investigations showed high amounts of parasympatholytic tropane alkaloids in a corolla area rich in Dargendorff-positive glandular hairs.
  
  
  CONCLUSIONS
  Simple topical exposure to the flowers of Angel's trumpet, without instillation of plant sap into the eye, can produce self-limited unilateral mydriasis.
  
  
  CONCLUSIONS
  This case adds to the differential diagnosis of acute anisocoria in otherwise healthy children. An accurate and detailed history will avoid unnecessary and expensive diagnostic tests. It is important for parents and garden suppliers have information about the potential adverse effects after handling Angel's trumpet plants.
authors: Department of Pediatrics, University of Padova, Padova, Italy.
authors: Barbara
authors: B
authors: Andreola
authors: Anna
authors: A
authors: Piovan
authors: Liviana
authors: L
authors: Da Dalt
authors: Raffaella
authors: R
authors: Filippini
authors: Elsa
authors: E
authors: Cappelletti
mesh_terms: D000470:Alkaloids / Q000032:analysis; D015875:Anisocoria / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D002648:Child; D013286:Datura stramonium / Q000737:chemistry / Q000506:poisoning* / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015878:Mydriasis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D010939:Plant Poisoning / Q000209:etiology* / Q000503:physiopathology; D010947:Plants, Toxic / Q000506:poisoning; D012075:Remission, Spontaneous
chemical_list: D000470:Alkaloids