title: [Left ventricular rotation and twist in patients with hypertrophic cardiomyopathy evaluated by two-dimensional ultrasound speckle-tracking imaging].
abstract: OBJECTIVE
  To assess the left ventricular rotation and twist in patients with hypertrophic cardiomyopathy (HCM) by 2-dimensional ultrasound speckle-tracking imaging (STI).
  
  
  METHODS
  Two-dimensional images of left ventricule (LV) at basal and apical short-axis views were acquired in 20 patients with HCM and 20 healthy subjects to evaluate LV rotation. LV twist were defined as rate of apical LV rotation to the basal. Peak rotation (Prot) and the time to Prot in basal and apical short axis views were measured separately. Peak twist (Ptw), twist at aortic valve closure (AVCtw), twist at mitral valve opening (MVOtw), untwisting rate (Untw R), and half time of untwisting (HTU) were calculated.
  
  
  RESULTS
  Compared with the control group, the value of Prot-MV, Prot-AP, Ptw, time to Ptw, AVCtw, MVOtw, and HTU significantly increased (all P < 0.05) and the Untw R significantly decreased (P < 0.05) in the HCM group. In the HCM group, time to Prot in apical view was significantly higher than that in basal view.
  
  
  CONCLUSIONS
  STI can noninvasively evaluate the characteristics of LV twist and rotation in patients with HCM.
authors: Hubei Provincial Key Laboratory of Molecular Imaging, Department of Ultrasound, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. xiemx64@126.com
authors: Ming-Xing
authors: MX
authors: Xie
authors: Li
authors: L
authors: Zhang
authors: Qing
authors: Q
authors: Lü
authors: Xin-Fang
authors: XF
authors: Wang
authors: Wei
authors: W
authors: Han
authors: Jing
authors: J
authors: Zhang
authors: Ying-Ying
authors: YY
authors: Liu
authors: Qian
authors: Q
authors: Fu
authors: Fei-Xiang
authors: FX
authors: Xiang
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000209:etiology; D014102:Torsion Abnormality / Q000000981:diagnostic imaging* / Q000209:etiology; D014463:Ultrasonography