Ultrastructure of ependyma in brain third ventricle of the rats exposed to repeated tail-suspension. Scanning electron microscopical study.
By means of scanning electron microscopy the ultrastructure of ependyma was studied in the brain third ventricle of the rats repeatedly exposed to 14-day tail-suspension (TS). Animals were subjected to TS for 30 days, then readapted to horizontal position during 30 days and again, repeatedly subjected to TS for 14 days simultaneously with the rats which were in TS for the first time during 14 days. Repeated TS of rats, inspite of repeated redistribution of body liquid mediums in cranial direction, results in considerably less expressed destructive changes in ultrastructure of ependymocyte cilia, then after primary 14- and 30-day TS, showing much greater cerebrospinal fluid (CSF) outflow from brain ventricles into sagittal venous sinus at postponed for a long time, repeated simulation of weightlessness effects in comparison with CSF outflow at primery one.
Sidorenko
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LA
State scientific centre of Russian Federation, Institute of Biomedical Problems RAS, Khoroshevskoje shosse, 76A, 123007, Moscow, Russia. bionomy@imbp.ru
Krasnov
I B
IB
Gulevskaja
T S
TS
Morgunov
V A
VA
D000222:Adaptation, Physiological; D000818:Animals; D002555:Cerebrospinal Fluid / Q000378:metabolism; D002923:Cilia / Q000648:ultrastructure; D003392:Cranial Sinuses / Q000378:metabolism; D004805:Ependyma / Q000378:metabolism / Q000648:ultrastructure*; D019417:Hindlimb Suspension; D008297:Male; D008855:Microscopy, Electron, Scanning; D051381:Rats; D017208:Rats, Wistar; D020542:Third Ventricle / Q000378:metabolism / Q000648:ultrastructure*; D013997:Time Factors