"Pagetoid" eccrine carcinoma of the vulva: report of an unusual case with review of the literature.
Sweat gland carcinoma of the vulva is rare and may be classified as being of eccrine, apocrine, or mixed origin. Most reported cases of vulvar sweat gland carcinomas associated with extramammary Paget disease describe a tumor of apocrine origin. We report a case of a vulvar sweat gland carcinoma of eccrine origin associated with Pagetoid extension. A review of the literature and the differential diagnosis are also presented. To our knowledge, this is the second case of vulvar sweat gland carcinoma of eccrine origin associated with extramammary Paget disease.
Grin
Andrea
A
Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Canada.
Colgan
Terrence
T
Laframboise
Stephane
S
Shaw
Patricia
P
Ghazarian
Danny
D
D000368:Aged; D001706:Biopsy; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D008197:Lymph Node Excision; D010145:Paget Disease, Extramammary / Q000175:diagnosis; D010388:Pelvis; D013544:Sweat Gland Neoplasms / Q000175:diagnosis*; D014846:Vulvar Neoplasms / Q000175:diagnosis*