title: New centrifugal blood pump with dual impeller and double pivot bearing system: wear evaluation in bearing system, performance tests, and preliminary hemolysis tests.
abstract: A new dual impeller centrifugal blood pump has been developed as a research collaboration between Baylor College of Medicine and Institute Dante Pazzanese of Cardiology for long-term left ventricle assist device (LVAD). A design feature of this new pump is a dual impeller that aims to minimize a stagnant flow pattern around the inlet port. Several different materials were tested in order to adopt a double pivot bearing design originally developed by Prof. Dr. Yukihiko Nosé from Baylor College of Medicine. Hydraulic performance tests were conducted with two different inlet ports' angle configurations 30 degrees and 45 degrees . Pump with inlet port angle of 45 degrees achieved best values of pressure ahead and flow after 1800 rpm. Preliminary hemolysis tests were conducted using human blood. The pump showed good performance results and no alarming trace of hemolysis, proving to be a feasible long-term LVAD.
authors: Department of Bioengineering, Institute Dante Pazzanese of Cardiology, IDPC, Sao Paulo, Brazil. bock@bcm.edu
authors: Eduardo
authors: E
authors: Bock
authors: Adriana
authors: A
authors: Ribeiro
authors: Maxwell
authors: M
authors: Silva
authors: Pedro
authors: P
authors: Antunes
authors: Jeison
authors: J
authors: Fonseca
authors: Daniel
authors: D
authors: Legendre
authors: Juliana
authors: J
authors: Leme
authors: Celso
authors: C
authors: Arruda
authors: José
authors: J
authors: Biscegli
authors: Denys
authors: D
authors: Nicolosi
authors: Aron
authors: A
authors: Andrade
mesh_terms: D001672:Biocompatible Materials; D002498:Centrifugation; D002516:Ceramics / Q000737:chemistry*; D004867:Equipment Design; D005240:Feasibility Studies; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006461:Hemolysis; D018056:Hemorheology; D006801:Humans; D008422:Materials Testing; D010865:Pilot Projects; D011108:Polymers / Q000737:chemistry*; D011312:Pressure; D012399:Rotation; D013314:Stress, Mechanical; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D011108:Polymers