title: T cell homeostasis.
abstract: The pool of mature T cells comprises a heterogeneous mixture of naive and memory CD4(+) and CD8(+) cells. These cells are long lived at a population level but differ markedly in their relative rates of turnover and survival. Here, we review how contact with exogenous stimuli, notably self MHC ligands and various gamma(c) cytokines, plays a decisive role in controlling normal T cell homeostasis.
authors: Immunology and Inflammation Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia. j.sprent@garvan.org.au
authors: Jonathan
authors: J
authors: Sprent
authors: Jae-Ho
authors: JH
authors: Cho
authors: Onur
authors: O
authors: Boyman
authors: Charles D
authors: CD
authors: Surh
mesh_terms: D000375:Aging; D000818:Animals; D049109:Cell Proliferation; D016207:Cytokines / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology* / Q000378:metabolism
chemical_list: D016207:Cytokines