Pumpless extracorporeal lung assist as supportive therapy in a patient with diffuse alveolar hemorrhage.
Our 18-year old female patient suffered from microscopic polyangiitis. After invasive diagnostics, a diffuse alveolar hemorrhage occurred, leading to acute lung failure. In spite of differential ventilation, respiratory insufficiency and lactate-acidosis increased quickly. Due to the massive hemorrhage, a pumpless extracorporeal lung assist was implanted and, after six hours, low-dose heparinization was started. In response to this therapy, hypercapnia and acidosis improved quickly and were completely eliminated within 24 hours. Simultaneously, treatment with prednisolon and cyclophosphamid was started. After 7 days, the patient's conditions allowed weaning from the pumpless extracorporeal lung assist and after 9 days she was extubated. In conclusion, the pumpless lung assist was shown to be a very practical option to treat the most serious forms of hypercapnia, especially for patients disposed to diffuse bleeding.
Renner
A
A
Clinic and Polyclinic of Cardiothoracic Surgery, University of Wuerzburg, Wuerzburg, Germany.
Neukam
K
K
Rösner
T
T
Elert
O
O
Lange
V
V
D000293:Adolescent; D005112:Extracorporeal Circulation; D005260:Female; D006470:Hemorrhage / Q000628:therapy*; D006801:Humans; D006935:Hypercapnia / Q000628:therapy; D008171:Lung Diseases / Q000534:rehabilitation*; D011650:Pulmonary Alveoli; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000628:therapy*