title: Environmental estrogenic effects and gonadal development in wild goldfish (Carassius auratus).
abstract: Serum vitellogenin (VTG) contents of wild goldfish (Carassius auratus) were investigated as a sensitive biomarker for artificial estrogenic compounds in aquatic environments. Goldfish was sampled from a pristine area, a river situated 5 km downstream from a sewage treatment works (STW), and also from the Young-San River in Korea. The female yolk precursor protein VTG was not detected when gonadosomatic index (GSI) was less than 0.85%, while VTG levels of >10 microg/ml were found in males whose GSI was less than 1.53%. In male goldfish sampled from STW and the Young-San River, the higher VTG corresponded to lower GSI. This study suggested a trend that gonad development was connected to VTG levels in both sexes, and the application of GSI and histological analysis provide an attractive possibility that it could be included in the panel of markers used for estrogenic activity investigation of aquatic environments.
authors: Department of Chemistry and Centre for Innovative Bio-physio Sensor Technology, Pusan National University, Busan, 609-735, South Korea.
authors: Chun-Ri
authors: CR
authors: Li
authors: Sang-Hoon
authors: SH
authors: Lee
authors: So-Sun
authors: SS
authors: Kim
authors: Andre
authors: A
authors: Kim
authors: Keun Woo
authors: KW
authors: Lee
authors: Ming
authors: M
authors: Lu
authors: Hee-Eun
authors: HE
authors: Kim
authors: Im-Jung
authors: IJ
authors: Kwak
authors: Yun-Ju
authors: YJ
authors: Lee
authors: Dong-Kyoo
authors: DK
authors: Kim
authors: Jung-Sick
authors: JS
authors: Lee
authors: Shin-Won
authors: SW
authors: Kang
authors: Min-Do
authors: MD
authors: Huh
authors: Kyu-Hyuck
authors: KH
authors: Chung
authors: Jang-Su
authors: JS
authors: Park
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D052244:Endocrine Disruptors / Q000494:pharmacology*; D004784:Environmental Monitoring; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D006054:Goldfish / Q000033:anatomy & histology / Q000502:physiology; D006066:Gonads / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D045483:Rivers / Q000737:chemistry; D012621:Seasons; D014819:Vitellogenins / Q000097:blood*; D014874:Water Pollutants, Chemical / Q000494:pharmacology
chemical_list: D015415:Biomarkers; D052244:Endocrine Disruptors; D004967:Estrogens; D014819:Vitellogenins; D014874:Water Pollutants, Chemical