Guillain-Barré syndrome.
Guillain-Barré syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. The diagnosis relies heavily on the clinical impression obtained from the history and examination, although cerebrospinal fluid analysis and electrodiagnostic testing usually provide evidence supportive of the diagnosis. The clinician must also be familiar with mimics and variants to promptly and efficiently reach an accurate diagnosis. Intravenous immunoglobulin and plasma exchange are efficacious treatments. Supportive care during and following hospitalization is also crucial.
Burns
Ted M
TM
Department of Neurology, University of Virginia, PO Box800394, Charlottesville, VA 22908, USA. tmb8r@virginia.edu
D003141:Communicable Diseases / Q000150:complications / Q000276:immunology; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004568:Electrodiagnosis; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007167:Immunotherapy / Q000379:methods / Q000592:standards; D008991:Monitoring, Physiologic / Q000592:standards; D009431:Neural Conduction / Q000276:immunology; D010525:Peripheral Nerves / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology*; D013997:Time Factors