Coordination of gene expression between organellar and nuclear genomes.
Following the acquisition of chloroplasts and mitochondria by eukaryotic cells during endosymbiotic evolution, most of the genes in these organelles were either lost or transferred to the nucleus. Encoding organelle-destined proteins in the nucleus allows for host control of the organelle. In return, organelles send signals to the nucleus to coordinate nuclear and organellar activities. In photosynthetic eukaryotes, additional interactions exist between mitochondria and chloroplasts. Here we review recent advances in elucidating the intracellular signalling pathways that coordinate gene expression between organelles and the nucleus, with a focus on photosynthetic plants.
Woodson
Jesse D
JD
Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.
Chory
Joanne
J
D002467:Cell Nucleus / Q000235:genetics* / Q000378:metabolism; D002736:Chloroplasts / Q000235:genetics* / Q000378:metabolism; D005057:Eukaryotic Cells / Q000502:physiology; D019143:Evolution, Molecular; D018506:Gene Expression Regulation, Plant / Q000502:physiology*; D054628:Genome, Chloroplast / Q000502:physiology*; D054629:Genome, Mitochondrial / Q000502:physiology*; D018745:Genome, Plant / Q000502:physiology*; D010940:Plant Proteins / Q000096:biosynthesis / Q000235:genetics; D010944:Plants / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
D010940:Plant Proteins