title: Photoallergic contact dermatitis to Heracleum giganteum.
abstract: Heracleum plants occur in numerous species worldwide and may cause phototoxic reactions due to its content of various furocoumarins. In this case report, a widespread photoallergic contact dermatitis after exposure to Heracleum giganteum (giant bear claw) is described. A photopatch test with extracts from the stem, leaves and seeds of the giant bear claw revealed a positive papulovesicular reaction that already appeared at 24 h and peaked at 72 h after irradiation with 5 J/cm(2) UVA. The unirradiated controls remained negative. We conclude that in rare cases Heracleum plants may cause severe photoallergic reactions that can be verified by photopatch testing.
authors: Division of General Dermatology, Medical University of Vienna, Vienna, Austria.
authors: Daniela
authors: D
authors: Karimian-Teherani
authors: Tamar
authors: T
authors: Kinaciyan
authors: Adrian
authors: A
authors: Tanew
mesh_terms: D000485:Allergens / Q000009:adverse effects*; D017454:Dermatitis, Photoallergic / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D030002:Heracleum / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D010328:Patch Tests; D018515:Plant Leaves; D018547:Plant Stems; D012639:Seeds
chemical_list: D000485:Allergens