Synaptic endocytosis: illuminating the role of clathrin assembly.
Acute photo-inactivation of clathrin in Drosophila synapses sheds new light on a 35-year-old debate over mechanisms of synaptic-vesicle endocytosis: clathrin is essential for reformation of functional synaptic vesicles, but not for bulk membrane internalization.
Rodal
Avital A
AA
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Littleton
J Troy
JT
D000818:Animals; D002966:Clathrin / Q000378:metabolism*; D004330:Drosophila; D034281:Dynamins / Q000378:metabolism; D004705:Endocytosis / Q000502:physiology*; D013572:Synaptic Vesicles / Q000378:metabolism*
D002966:Clathrin; D034281:Dynamins