Standardization of magnetocardiography in nonhuman primates.
To establish the electrophysiological mappings of nonhuman primates by using magnetocardiogram (MCG) data and obtain the normal values of MCG parameters, we used 64-channel superconducting quantum interference devices to measure 8x8 MCG data for 95 cynomolgus monkeys (Macaca fascicularis, 51 female and 44 male). The PQ interval, QRS duration, QT interval and QTc were respectively 79+/-14 ms, 42+/-7 ms, 222+/-23 ms and 363+/-25 (mean+/-SD), and these parameters did not differ significantly between female and male monkeys. These results indicate the normal values of the MCG parameters of the cynomolgus monkey and should facilitate animal experiments in magnetocardiography.
Seki
Yusuke
Y
Advanced Research Laboratory, Hitachi Ltd. 1-280 Higashi-Koigakubo, Kokubunji, Tokyo 185-8601, Japan. yusuke.seki.hp@hitachi.com
Muneyuki
Kenta
K
Kandori
Akihiko
A
Tsukada
Keiji
K
Terao
Keiji
K
Ageyama
Naohide
N
D000818:Animals; D005260:Female; D008252:Macaca fascicularis; D053798:Magnetocardiography / Q000592:standards*; D008297:Male; D012015:Reference Standards