title: A comparison of augmentation techniques for reconstruction of the extensor mechanism following proximal tibial replacement in an experimental animal model.
abstract: We used an in vivo model to assess the use of an autogenous cancellous bone block and marrow graft for augmenting tendon reattachment to metallic implants. We hypothesised that augmentation of the tendon-implant interface with a bone block would enable retention of the graft on the implant surface, enhance biological integration, and result in more consistent functional outcomes compared with previously reported morcellised graft augmentation techniques. A significant improvement in functional weight-bearing was observed between six and 12 weeks. The significant increase in ground reaction force through the operated limb between six and 12 weeks was greater than that reported previously with morcellised graft augmented reconstructions. Histological appearance and collagen fibre orientation with bone block augmentation more closely resembled that of an intact enthesis compared with the morcellised grafting technique. Bone block augmentation of tendon-implant interfaces results in more reliable functional and histological outcomes, with a return to pre-operative levels of weight-bearing by 24 weeks.
authors: The Centre for Biomedical Engineering, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK. c.pendegrass@ucl.ac.uk
authors: C J
authors: CJ
authors: Pendegrass
authors: S
authors: S
authors: Sundar
authors: M J
authors: MJ
authors: Oddy
authors: S R
authors: SR
authors: Cannon
authors: T
authors: T
authors: Briggs
authors: G W
authors: GW
authors: Blunn
mesh_terms: D000818:Animals; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005684:Gait / Q000502:physiology; D023421:Models, Animal; D016059:Range of Motion, Articular / Q000502:physiology; D019651:Plastic Surgery Procedures / Q000379:methods; D012756:Sheep; D013710:Tendons / Q000033:anatomy & histology / Q000503:physiopathology; D013977:Tibia / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery*; D016474:Weight-Bearing / Q000502:physiology*