title: Wide-bore 1.5 Tesla MR imagers for guidance and monitoring of radiofrequency ablation of renal cell carcinoma: initial experience on feasibility.
abstract: This study was conducted to test and demonstrate the feasibility of magnetic resonance (MR)-guided radiofrequency (RF) ablation of renal cell carcinoma (RCC) using a 1.5 T whole-body scanner equipped with a wide-bore superconductive magnet. Two patients with contrast-enhancing renal masses were treated with multipolar RF ablation (Celon ProSurge). Applicator navigation and near real-time ablation monitoring were performed in a wide-bore 1.5 T scanner using adapted fluoroscopic and diagnostic sequences. In addition to T2-weighted imaging for ablation monitoring, perfusion-weighted images acquired with an arterial spin-labeling technique (FAIR-TrueFISP) were applied. Results were compared to a previous study on 12 patients performed at 0.2 T. Navigation and monitoring of RF ablation using the wide-bore system operating at 1.5 T were clearly improved compared to former experiences on a 0.2 T MR unit. Fluoroscopic and diagnostic images for MR guidance could be acquired with distinctly higher image quality and shorter acquisition time resulting in higher accuracy of applicator placement and shorter treatment time. Spin-labeling perfusion imaging exhibited good image quality, potentially providing additional clinically important information. MR-guided RF ablation of RCC can safely be performed in a 1.5 T wide-bore scanner offering higher image quality, shorter acquisition time, and new monitoring modalities not feasible at 0.2 T.
authors: Section of Experimental Radiology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany. andreas.boss@med.uni-tuebingen.de
authors: Andreas
authors: A
authors: Boss
authors: Hansjörg
authors: H
authors: Rempp
authors: Petros
authors: P
authors: Martirosian
authors: Stephan
authors: S
authors: Clasen
authors: Christina
authors: C
authors: Schraml
authors: Arnulf
authors: A
authors: Stenzl
authors: Claus D
authors: CD
authors: Claussen
authors: Fritz
authors: F
authors: Schick
authors: Philippe L
authors: PL
authors: Pereira
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000601:surgery*; D017115:Catheter Ablation; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation*; D008297:Male; D013113:Spin Labels; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D013113:Spin Labels