title: Ethnic variations in the distribution of obesity and biochemical metabolic abnormalities in fertility clinic attendees.
abstract: OBJECTIVE
  To assess ethnic variations in the distribution of obesity and the associated biochemical, metabolic abnormalities in young women of reproductive age.
  
  
  METHODS
  Baseline anthropometric, biochemical and endocrine parameters were compared between 30 South Asian (SA) and 41 Caucasian (CA) women attending a fertility clinic.
  
  
  RESULTS
  The CA were significantly more obese (BMI > 30 kg/m2) than the SA (p = 0.001); however, there was no difference in waist circumference. The SA were significantly more hyperinsulinemic (p = 0.04) and had lower levels of plasma high density lipoprotein-c (p = 0.02) than the CA. Metabolic abnormalities increased in the SA with a BMI > 25 kg/m2, and the group showed a 4.6-fold greater prevalence of metabolic syndrome (MS) than did the CA.
  
  
  CONCLUSIONS
  SAs have a higher prevalence of MS than CAs, and the risk is even higher in the SA polycystic ovary syndrome subgroup. MS criteria need to be redefined in terms of obesity in SA, and the role of community-based preventive measures in young women needs to be emphasized.
authors: University Department of Reproductive Medicine and Surgery, Addenbrookes National Health Service Trust, Cambridge, UK. singhrajpal@hotmail.com
authors: Manisha
authors: M
authors: Palep-Singh
authors: Helen M
authors: HM
authors: Picton
authors: Julian H
authors: JH
authors: Barth
authors: Adam H
authors: AH
authors: Balen
mesh_terms: D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000208:ethnology*; D009765:Obesity / Q000208:ethnology*; D011085:Polycystic Ovary Syndrome / Q000208:ethnology*; D044465:White People