title: Classification of saphenous refluxes: implications for treatment.
abstract: OBJECTIVE
  To determine the possible correlations of patient age, symptoms and signs with findings of Doppler duplex examination in limbs with varicose veins.
  
  
  METHODS
  A total of 2275 ultrasound examinations were done on 2275 limbs of 1751 patients (421 men and 1330 women). Ages ranged from 21 to 94 years (mean 50). Symptoms of aching, heaviness, burning pain (venous neuropathy) were recorded, and signs of ankle hyperpigmentation, scars of healed ulcers and presence of open venous ulcers were noted.
  
  
  RESULTS
  Presence of symptoms was associated with advancing patient age (50.7 vs. 48.8 years). Varicose veins without great saphenous reflux correlated with younger age (43 vs. 53.5 years). Presence of saphenofemoral junctional incompetence correlated with an older age (54.7 vs. 49.8 years), and reflux to the ankle (Hach stage IV) also correlated with older age (mean 63.7 years). A younger age was associated with less advanced signs (C0-C2: 49.1 vs. C4-C6: 60.1 years). Saphenous vein reflux without clinical varices was associated with more advanced signs (C4-C6: 21.3%).
  
  
  CONCLUSIONS
  Ageing is associated with advancing clinical symptoms, signs and increasing multifocal reflux in limbs with venous insufficiency. These facts support the concept of early treatment of venous insufficiency before predictable deterioration occurs.
authors: Riviera Veine Institut, Nice, France. paulpittaluga@hotmail.com
authors: P
authors: P
authors: Pittaluga
authors: S
authors: S
authors: Chastane
authors: B
authors: B
authors: Rea
authors: R
authors: R
authors: Barbe
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000503:physiopathology; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000503:physiopathology*; D018616:Ultrasonography, Doppler, Duplex; D014647:Varicose Ulcer / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D014689:Venous Insufficiency / Q000145:classification* / Q000150:complications / Q000503:physiopathology / Q000628:therapy