Overview of drug delivery and alternative methods to electroporation.
This chapter provides an overview of the application of electroporation to areas other than gene delivery. These areas include the delivery of drugs and vaccines to tissues and tumors as well as into and through the skin. Achievements and limitations of electroporation in these areas are presented. Alternative physical methods for gene and drug delivery besides electroporation are described. The advantages and drawbacks of electroporation, compared with these methods, are also discussed.
Hui
Sek-Wen
SW
Cancer Biology Department, Roswell Park Cancer Institute, University at Buffalo, Buffalo, NY, USA.
D000279:Administration, Cutaneous; D000700:Analgesics / Q000008:administration & dosage; D000777:Anesthetics / Q000008:administration & dosage; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D019470:Biolistics; D016503:Drug Delivery Systems / Q000379:methods*; D053672:Electrochemotherapy / Q000379:methods; D018274:Electroporation / Q000379:methods*; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D006874:Hydrostatic Pressure; D007834:Lasers; D008280:Magnetics; D045423:Microbubbles; D053758:Nanoparticles; D009369:Neoplasms / Q000188:drug therapy; D022223:Vaccines, Subunit / Q000008:administration & dosage
D000700:Analgesics; D000777:Anesthetics; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D022223:Vaccines, Subunit