title: A nationwide population study of severe head injury and Parkinson's disease.
abstract: The aim was to analyze prospectively the association between severe head injury and Parkinson's disease. All people in Denmark who were at least 20 years old as on 1 January 1981 were followed for hospitalisation due to previous head trauma during 1981-1993 and for hospital contacts due to PD during 1995-2004. We observed 107 cases of PD among people at hypothetical risk due to previous head injury. The expected number was 112.1, which yielded a standardised morbidity ratio of 0.954 (95% CI: 0.782-1.15). The study provides no support for severe head injury among adults being a risk factor for Parkinson's disease.
authors: National Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100 Copenhagen, Denmark.
authors: Søren
authors: S
authors: Spangenberg
authors: Harald
authors: H
authors: Hannerz
authors: Finn
authors: F
authors: Tüchsen
authors: Kim L
authors: KL
authors: Mikkelsen
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006259:Craniocerebral Trauma / Q000453:epidemiology*; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D010300:Parkinson Disease / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors