Hemorrhagic cerebellar anaplastic glioma appearing 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia.
A radiation-induced cerebellar glioma is extremely rare, and the etiology of such a tumor is unknown. We report a rare case of hemorrhagic cerebellar anaplastic glioma occurring 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia. We discuss the etiologies of the radiation-induced hemorrhagic cerebellar glioma as a secondary malignancy after radiotherapy.
Miyazawa
Takahito
T
Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan. yosateke@ndmc.ac.jp
Aida
Shinsuke
S
Shima
Katsuji
K
D000328:Adult; D000708:Anaplasia / Q000209:etiology / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000209:etiology* / Q000473:pathology; D005910:Glioma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology* / Q000473:pathology; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects; D013997:Time Factors