Reaction of 5-aminotetrazole with vinamidinium salts: formation of 2-(N, N-dimethylamino)-5-substituted pyrimidines.
The cyclocondensation of vinamidinium salts with 5-aminotetrazole in basic media affords regiospecifically good yields of 2-(N, N-dimethylamino)-5- aryl-, arylsulfonyl- and 2-(N, N-dimethylamino)-5-formyl-pyrimidines, respectively.
Adnen
Hadj Ayed Med
HA
Laboratoire de Synthèse Organique Asymétrique et Catalyse Homogène (01UR1201), Faculté des Sciences de Monastir, Monastir, 5019, Tunisia.
Jameleddine
Khiari
K
Bechir
Ben Hassine
BH
D018360:Crystallography, X-Ray; D011743:Pyrimidines / Q000737:chemistry*; D012492:Salts / Q000737:chemistry*; D013777:Tetrazoles / Q000737:chemistry*
D011743:Pyrimidines; D012492:Salts; D013777:Tetrazoles; C001573:5-amino-1H-tetrazole