title: [Cryoablation of prostate cancer].
abstract: Because of continuous technical development for more than half a century, followed by better clinical results with minimal side effects, cryoablation of the prostate for localized prostate cancer has evolved as a true alternative therapeutic option in selected cases. Today's form of cryotherapy has almost nothing in common with those versions established in the 1970s and further developed in the 1990s. Nowadays it shows minimal invasiveness and high efficacy for treatment of high-risk carcinomas and failures of other therapeutic modalities. Cryoablation of the prostate is indicated if there are absolute or relative contraindications for radical surgery. In localized prostate cancer, cryoablation is the therapy of choice for salvage cases; standardisation of the procedure, definition of freeze-thaw cycles, and structured training programs have led to this status.
authors: Klinik für Urologie und Kinderurologie, Krankenhaus Nordwest, Stiftung Hospital zum Heiligen Geist, Steinbacher Hohl 2-26, 60488 Frankfurt/Main, Deutschland. witzsch.ullrich@khnw.de
authors: U K F
authors: UK
authors: Witzsch
authors: K
authors: K
authors: Skriapas
authors: E
authors: E
authors: Becht
mesh_terms: D003452:Cryosurgery / Q000295:instrumentation*; D019160:Endosonography / Q000295:instrumentation*; D004867:Equipment Design; D007172:Erectile Dysfunction / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000209:etiology; D011468:Prostatectomy / Q000295:instrumentation*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016879:Salvage Therapy; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000295:instrumentation*