title: Erythromelalgia of the ears: an unusual variant and response to therapy.
abstract: Erythromelalgia is characterized by episodes of erythematous, warm, burning acral skin, which is exacerbated by heat and relieved by cold. Erythromelalgia usually affects the feet and/or hands but, although rare, erythromelalgia may affect the ears. The authors present a 65-year-old woman with erythromelalgia of the ears with disabling symptoms whose diagnosis was delayed for 6 years. The patient failed to respond to numerous therapies before rapidly improving with oral amitriptyline and amitriptyline 1% to 2% and ketamine 0.5% to 1% topical gel.
authors: Division of Dermatology, Washington University School of Medicine, St. Louis, MO 63110, USA. DBerk@im.wustl.edu
authors: David R
authors: DR
authors: Berk
authors: Arthur Z
authors: AZ
authors: Eisen
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000639:Amitriptyline / Q000008:administration & dosage*; D000700:Analgesics / Q000008:administration & dosage*; D004338:Drug Combinations; D004423:Ear / Q000473:pathology; D004427:Ear Diseases / Q000175:diagnosis / Q000188:drug therapy; D004916:Erythromelalgia / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005782:Gels; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage*; D012867:Skin / Q000473:pathology
chemical_list: D000700:Analgesics; D004338:Drug Combinations; D005782:Gels; D000639:Amitriptyline; D007649:Ketamine