Fortuneanosides G-L, dibenzofuran glycosides from the fruit of Pyracantha fortuneana.
Six new dibenzofuran glycosides, fortuneanosides G (1), H (2), I (3), J (4), K (5), and L (6), were isolated from the fruit of Pyracantha fortuneana (MAXIM) LI. Their structures were determined to be 3,7-dihydroxy-2,4-dimethoxy-dibenzofuran 7-O-beta-D-glucopyranoside, 3,7-dihydroxy-2,4-dimethoxy-dibenzofuran 7-O-(alpha-L-rhamnopyranosyl)-(1-6)-beta-D-glucopyranoside, 3,6-dihydroxy-2,4-dimethoxy-dibenzofuran 6-O-beta-D-glucopyranoside, 2,4-dimethoxy-3,6,9-trihydroxy-dibenzofuran 6-O-beta-D-glucopyranoside, 3,9-dihydroxy-2,4-dimethoxy-dibenzofuran 3-O-beta-D-glucopyranoside, and 2-methoxy-3,4,9-trihydroxy-dibenzofuran 4-O-beta-D-glucopyranoside based on spectroscopic analysis. Fortuneanosides G-J showed more potent tyrosinase-inhibitory activity than arbutin.
Dai
Yi
Y
Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.
Zhou
Guang-Xiong
GX
Kurihara
Hiroshi
H
Ye
Wen-Cai
WC
Yao
Xin-Sheng
XS
D001104:Arbutin / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors; D031991:Pyracantha / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D001572:Benzofurans; D004791:Enzyme Inhibitors; D006027:Glycosides; D001104:Arbutin; D014442:Monophenol Monooxygenase