[Surgical or biologic sphincterotomy in the treatment of chronic anal fissure].
BACKGROUND
Chronic anal fissure is a lineal ulcer of the lower part of the anal canal. It is a painful condition characterized by postdefecational pain and bleeding. It is associated with internal anal sphincter spasm. The relief of internal anal sphincter spasm is the key for providing fissure healing. Gold standard in the treatment of chronic anal fissure is partial lateral internal anal sphincterotomy.


METHODS
Sixty patients with chronic anal fissure were randomly assigned into two groups treated either by surgical sphincterotomy or injections of botulinum toxin into internal anal sphincter. Manometric measurements were performed before and three months after treatment. Follow up period was six months. The aim of the study was to compare results between these two groups.


RESULTS
Both methods efficiently reduced resting anal pressure and successfully healed chronic anal fissure.


CONCLUSIONS
Surgical and biologic sphincterotomy are almost equally effective in the treatment of chronic anal fissure. Injecting botulinum toxin into internal anal sphincter is a safe, easy to apply and effective method in the management of anal fissure.
Suknaić
Slaven
S
University Department of Surgenr, Merkur University Hospital, Zagreb, Croatia. ssuknaic@inet.hr
Patrlj
Leonardo
L
Steresinić
Mario
M
Skopljanac Macina
Andrija
A
Erdelez
Lidija
L
D000328:Adult; D001003:Anal Canal / Q000601:surgery; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D002908:Chronic Disease; D005260:Female; D005401:Fissure in Ano / Q000628:therapy*; D006801:Humans; D007267:Injections; D008297:Male; D009465:Neuromuscular Agents / Q000008:administration & dosage
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A