title: Drug use patterns in severely mentally ill Medicare beneficiaries: impact of discontinuities in drug coverage.
abstract: OBJECTIVE
  To describe the extent of drug coverage among severely mentally ill Medicare beneficiaries and to determine whether and to what extent discontinuities in prescription drug coverage influence the use of medications used to treat serious mental health conditions.
  
  
  METHODS
  1997-2001 Medicare Current Beneficiary Surveys.
  
  
  METHODS
  We use a zero-inflated negative binomial model to estimate: (1) the probability of not receiving any mental health drug and (2) the number of medications received, adjusting for age, race, income, census region, health status, and comorbidity. Severe mental illness is defined using inpatient and outpatient claims with ICD-9 codes of schizophrenia, other psychotic disorders, bipolar disorders, and major depression. Mental health medications include antidepressants, antipsychotics, mood stabilizers, anxiolytic/sedative-hypnotics, and stimulants. Prescription drug coverage is assessed as full coverage (0 percent discontinuities), no coverage (100 percent discontinuities), or as discontinuous coverage, measured as 1-25, 26-50, and 51-99 percent of time without coverage.
  
  
  METHODS
  We constructed three 3-year longitudinal cohorts of severely mentally ill Medicare beneficiaries residing in the community (n=901).
  
  
  RESULTS
  Severely mentally ill Medicare beneficiaries with drug coverage discontinuities are more likely than their continuously insured peers not to receive medications used to treat mental health disorders, with the most significant impact seen in the probability of receiving any psychiatric medications. Analysis of two therapeutic classes-antidepressants and antipsychotics-revealed varying impacts of drug gaps on both probability of any drug use, as well as number of medications received among users.
  
  
  CONCLUSIONS
  Severely mentally ill Medicare beneficiaries may be particularly vulnerable to the Medicare Part D drug benefit design and, as such, warrant close evaluation and monitoring to insure adequate access to and utilization of medications used to manage mental illness.
authors: Peter Lamy Center on Drug Therapy and Aging, University of Maryland Baltimore School of Pharmacy, 220 Arch Street, 12th Floor, Baltimore, MD 21201, USA.
authors: Linda
authors: L
authors: Simoni-Wastila
authors: Ilene H
authors: IH
authors: Zuckerman
authors: Thomas
authors: T
authors: Shaffer
authors: Christopher M
authors: CM
authors: Blanchette
authors: Bruce
authors: B
authors: Stuart
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000191:economics / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000191:economics / Q000627:therapeutic use; D002491:Central Nervous System Agents / Q000191:economics* / Q000627:therapeutic use*; D004363:Drug Utilization; D005260:Female; D006801:Humans; D007182:Income / Q000706:statistics & numerical data; D007345:Insurance Claim Review; D008137:Longitudinal Studies; D008297:Male; D008484:Medicaid / Q000191:economics; D054524:Medicare Part D; D001523:Mental Disorders / Q000188:drug therapy* / Q000191:economics*; D008875:Middle Aged; D014481:United States
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D002491:Central Nervous System Agents