Intragastric alendronate therapy in two infants with vitamin D intoxication: a new method.
In recent years, alendronate, an oral biphosphonate, has been added to therapy of hypercalcemia secondary to vitamin D intoxication in children. Alendronate may cause mucosal ulcerations in the mouth and esophagus. We report our experience in two infants with vitamin D intoxication to whom alendronate therapy was administered through nasogastric tube, an alternate route for alendronate administration.
Doneray
Hakan
H
Ataturk University Faculty of Medicine, Erzurum, Turkey. hdoneray@hotmail.com
Ozkan
Behzat
B
Caner
Ibrahim
I
Ozkan
Asuman
A
Karakelleoglu
Cahit
C
D019386:Alendronate / Q000627:therapeutic use*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy*; D007223:Infant; D007441:Intubation, Gastrointestinal; D008297:Male; D009397:Nephrocalcinosis / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D014807:Vitamin D / Q000506:poisoning*
D050071:Bone Density Conservation Agents; D014807:Vitamin D; D019386:Alendronate