Elastosis perforans serpiginosa, Down syndrome, and moyamoya disease.
A 16-year-old girl with Down syndrome, moyamoya disease, and history of a previous stroke presented with acute onset of left hemiparesis and elastosis perforans serpiginosa. Elastosis perforans serpiginosa in a patient with Down syndrome and moyamoya disease is a novel finding. Development of elastosis perforans serpiginosa in association with progressive vaso-occlusive disease may be a biological marker of progression of moyamoya disease.
Espinosa
Patricio S
PS
Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky 40536-0284, USA. psespi2@email.uky.edu
Baumann
Robert J
RJ
Vaishnav
Anand G
AG
D000293:Adolescent; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy