title: Travel time to dialysis as a predictor of health-related quality of life, adherence, and mortality: the Dialysis Outcomes and Practice Patterns Study (DOPPS).
abstract: BACKGROUND
  Longer travel time to the dialysis unit creates a substantial burden for many patients. This study evaluated the effect of self-reported 1-way travel time to hemodialysis on mortality, health-related quality of life (HR-QOL), adherence, withdrawal from dialysis therapy, hospitalization, and transplantation.
  
  
  METHODS
  Prospective observational cohort.
  
  
  METHODS
  Patients enrolled in the Dialysis Outcomes and Practices Patterns Study who completed a patient questionnaire (n = 20,994).
  
  
  METHODS
  One-way travel time to hemodialysis treatment, categorized as 15 or less, 16 to 30, 31 to 60, and longer than 60 minutes. Covariates included demographics, comorbid conditions, serum albumin level, time on dialysis therapy, and country.
  
  
  METHODS
  HR-QOL was examined by using a linear mixed model. Cox proportional hazards regression was used to examine associations with mortality, withdrawal from dialysis therapy, hospitalization, and transplantation.
  
  
  RESULTS
  Longer travel time was associated with greater adjusted relative risk (RR) of death (P = 0.05 for overall trend). Adjusted HR-QOL subscales were significantly lower for those with longer travel times compared with those traveling 15 minutes or less. There were no associations of travel time with withdrawal from dialysis therapy (P = 0.6), hospitalization (P = 0.4), or transplantation (P = 0.7).
  
  
  CONCLUSIONS
  The questionnaire nonresponse rate was substantial, and nonresponders were older, with more comorbid conditions. Travel time was assessed by using a single nonvalidated question.
  
  
  CONCLUSIONS
  Longer travel time is associated significantly with greater mortality risk and decreased HR-QOL. Exploring opportunities to decrease travel time should be incorporated into the dialysis clinical routine.
authors: Division of Nephrology, London Health Sciences Center and Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
authors: Louise M
authors: LM
authors: Moist
authors: Jennifer L
authors: JL
authors: Bragg-Gresham
authors: Ronald L
authors: RL
authors: Pisoni
authors: Rajiv
authors: R
authors: Saran
authors: Takashi
authors: T
authors: Akiba
authors: Stefan H
authors: SH
authors: Jacobson
authors: Shunichi
authors: S
authors: Fukuhara
authors: Donna L
authors: DL
authors: Mapes
authors: Hugh C
authors: HC
authors: Rayner
authors: Akira
authors: A
authors: Saito
authors: Friedrich K
authors: FK
authors: Port
mesh_terms: D005260:Female; D006297:Health Services Accessibility / Q000706:statistics & numerical data*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011788:Quality of Life; D006435:Renal Dialysis; D013997:Time Factors