In vitro antimicrobial activity and antagonistic effect of essential oils from plant species.
Kahramanmaras, is a developing city located in the southern part of Turkey Thymus eigii (M. Zohary and RH. Davis) Jalas, Pinus nigraAm. sub sp pallasiana and Cupressus sempervirens L. are the useful plants of the Kahramanmaras province and have been understudy since 2004 for the traditional uses of plants empiric drug, spice, herbal tea industry herbal gum and fuel. The study was designed to examine the antimicrobial activities of essential oils of these plants by the disc diffusion and minimum inhibitory concentration (MIC) methods. In addition, antimicrobial activity of Thymus eigii was researched by effects when it was used together with antibiotics and even when it was combined with other essential oils. When the results of this study were compared with vancomycin (30 mcg) and erytromycin (15 mcg) standards, it was found that Thymus eigii essential oil was particularly found to possess strongerantimicrobial activity whereas other essential oils showed susceptible or moderate activity However, antimicrobial activity changed also by in vitro interactions between antibiotics and Thymus eigii essential oil, also between essential oils of these plants and that of Thymus eigii causing synergic, additive, antagonist effect.
Toroglu
Sevil
S
Department of Biology, Faculty of Arts and Science, Kahramanmaras Sutculmam University, Kahramanmaras-46045, Turkey. storoglu@ksu.edu.tr
D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D029781:Cupressus / Q000737:chemistry*; D004336:Drug Antagonism; D004357:Drug Synergism; D004917:Erythromycin / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000494:pharmacology*; D028223:Pinus / Q000737:chemistry*; D046930:Thymus Plant / Q000737:chemistry*; D014640:Vancomycin / Q000494:pharmacology*; D015003:Yeasts / Q000187:drug effects
D000890:Anti-Infective Agents; D009822:Oils, Volatile; D004917:Erythromycin; D014640:Vancomycin