An efficient total synthesis of (+/-)-stemonamine.
An efficient first approach to the Stemona alkaloid (+/-)-Stemonamine has been developed on the basis of a key TiCl4 promoted tandem Semipinacol rearrangement/Schmidt reaction and a Dieckmann condensation reaction.
Zhao
Yu-Ming
YM
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, PR China.
Gu
Peiming
P
Tu
Yong-Qiang
YQ
Fan
Chun-An
CA
Zhang
Qingwei
Q
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D001381:Azepines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D041901:Stemonaceae / Q000737:chemistry; D013237:Stereoisomerism; D014025:Titanium / Q000737:chemistry*
D000470:Alkaloids; D001381:Azepines; C530508:stemonamine; C025096:titanium tetrachloride; D014025:Titanium; D015107:4-Butyrolactone