title: Synchronous mucosa-associated lymphoid tissue lymphoma and gastrointestinal stromal tumor of the stomach presenting with gastric bleeding.
abstract: We report an extraordinarily rare case of synchronous mucosa-associated lymphoid tissue lymphoma and gastrointestinal stromal tumor of the stomach. An 80-year-old man presented with gastric bleeding. Gastroscopy showed an ulcerative lesion and a submucosal tumor at the upper corpus of the stomach. The ulcerative lesion was proven by biopsy to be mucosa-associated lymphoid tissue lymphoma, but the submucosal tumor could not be diagnosed. Due to the repeating episodes of massive gastric bleeding, a total gastrectomy with lymphadenectomy was performed. After the operation, the submucosal tumor was pathologically proven to be a gastrointestinal stromal tumor. In this case, synchronous occurrence of mucosa-associated lymphoid tissue lymphoma and gastrointestinal stromal tumor seems to be coincidental rather than related with the same pathogenic triggering. Surgical resection of the stomach provided an accurate diagnosis and an effective treatment.
authors: Department of Surgery, Rakuwakai-Otowa Hospital, Kyoto, Japan. rakuwadr011@rakuwadr.com
authors: Tetsuya
authors: T
authors: Yamaguchi
authors: Hiroshi
authors: H
authors: Takahashi
authors: Ryuzaburo
authors: R
authors: Kagawa
authors: Ryoji
authors: R
authors: Takeda
authors: Shingo
authors: S
authors: Sakata
authors: Michihiro
authors: M
authors: Yamamoto
authors: Daisuke
authors: D
authors: Nishizaki
authors: Hiroshi
authors: H
authors: Yasui
mesh_terms: D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005743:Gastrectomy; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery