title: [MRI after renal transplantation with dysfunctional allograft: are there typical diagnoses in the early and late postoperative phases?].
abstract: OBJECTIVE
  The aim of this study was to evaluate the different MRI diagnoses in the early and late post-operative period after renal transplantation with dysfunctional allograft.
  
  
  METHODS
  Due to unknown transplant dysfunction, 49 patients (30-male, 19 female) received a total of 74 MRI studies. According to the date of examination all MRI studies were divided in an early (< or = 60 days, ETP) and a late post-transplant time period (> 60 days, LTP). All MRI studies were performed on 1.5 T MRI systems using a standardised imaging protocol consisting of a morphological (pre- and post-contrast enhanced T (1)- and T (2)-weighted TSE sequences), a vascular (contrast-enhanced 3D MRA) and a urographical part (Flash 3D sequences). Frequencies of diagnoses in ETP and LTP, and diagnoses within each transplant time period were analysed.
  
  
  RESULTS
  44/74 MRI studies were performed in ETP, 30/74 in LTP. In total 80 diagnoses were obtained: Renal artery stenosis (ETP, n = 21; LTP, n = 5), renal vein stenosis (ETP, n = 2), renal vein thrombosis (ETP, n = 2), renal perfusion defect (ETP, n = 11), rejection (ETP, n = 1; LTP, n = 2), abscess (ETP, n = 1), urinary outflow obstruction (LTP, n = 4), without MRI pathology (ETP, n = 11; LTP, n = 20). Renal artery stenosis was the most prevalent diagnosis in ETP, and a more frequent finding in ETP compared to LTP (p < 0.05). Renal perfusion defects were more frequent in ETP than in LTP (p < 0.05). In the ETP vascular diseases (34/49 diagnoses) were more frequent (p < 0.05) than uropathological diseases (0/49 diagnoses).
  
  
  CONCLUSIONS
  Our results indicate that vascular diseases are a more frequent occurrence in the early post-operative course after renal transplantation than uropathological diseases. However, a transplant follow-up MRI study needs to contain a morphological, vascular and functional imaging part to answer combined clinical questions.
authors: Institut für Röntgendiagnostik, Universitätsklinikum Würzburg. weininger@roentgen.uni-wuerzburg.de
authors: M
authors: M
authors: Weininger
authors: E
authors: E
authors: Gerharz
authors: K
authors: K
authors: Lopau
authors: T
authors: T
authors: Pabst
authors: W
authors: W
authors: Kenn
authors: H
authors: H
authors: Riedmiller
authors: D
authors: D
authors: Hahn
authors: M
authors: M
authors: Beissert
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012078:Renal Artery Obstruction / Q000175:diagnosis*; D013997:Time Factors; D014184:Transplantation, Homologous; D018616:Ultrasonography, Doppler, Duplex; D014567:Urography / Q000379:methods
chemical_list: D003287:Contrast Media