A second biopsy?--Tandem lesion.
This is a rare case of synchronous pituitary adenoma and PNET in an adult and first of this sort in the literature. The MR appearances suggest a single pathological entity causing the changes in the different anatomical location which can occur in cases of germ cell tumours, PNET and glioblastoma. In certain cases, histological confirmation may be warranted for the different lesions. Both pathologies have different treatment strategy and outlook depending on the age, extent of the disease and Karnofsky score.
Ganesan
D
D
Department of Neurosurgery, Addenbrooke's Hospital, Cambridge, UK.
Dean
A F
AF
Antoun
N
N
Kirollos
R W
RW
D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D018242:Neuroectodermal Tumors, Primitive / Q000175:diagnosis* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012658:Sella Turcica; D014057:Tomography, X-Ray Computed