title: Micro-robotic deposition guidelines by a design of experiments approach to maximize fabrication reliability for the bone scaffold application.
abstract: This work aims to facilitate the transition of micro-robotic deposition (microRD) technology from the research bench to a mass manufacturing environment. The bone scaffolding application is targeted; however, the evaluation process developed is applicable to multiple colloidal material systems, length scales, and structure architectures. A design of experiments (DoE) approach is used to develop statistical correlations between three manufacturing treatments (material calcination time, nozzle size, and deposition speed) and defined reliability metrics. All three selected treatments have a significant effect on structure quality. A longer material calcination time improves the deposition of internal features. Logically, a larger nozzle size decreases structural defects. However, an unexpected result is revealed by this study. Higher deposition speeds are shown to either significantly improve or have no effect on structure quality, permitting a decrease in manufacturing time without adverse consequences.
authors: University of Illinois at Urbana-Champaign, Urbana, IL, USA.
authors: David J
authors: DJ
authors: Hoelzle
authors: Andrew G
authors: AG
authors: Alleyne
authors: Amy J
authors: AJ
authors: Wagoner Johnson
mesh_terms: D000704:Analysis of Variance; D001842:Bone and Bones; D017886:Durapatite / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D011208:Powders; D012212:Rheology; D012371:Robotics / Q000379:methods*; D013997:Time Factors; D054457:Tissue Scaffolds
chemical_list: D011208:Powders; D017886:Durapatite