title: Development of a method to study the migration of six photoinitiators into powdered milk.
abstract: The aim of the present work was to develop a rapid multimethod for the analysis of six photoinitiators (PIs) in powdered milk and to study the migration of these PIs from LDPE packaging into powdered milk. The optimized HPLC-DAD method showed high correlation coefficients (>0.9999) over a concentration range of 0.1-10.9 mg/L. The kinetics of migration of the photoinitiators from LDPE packaging into powdered milk were determined at different temperatures. The key parameters of migration phenomena (diffusion and partition coefficients) were determined. The diffusion coefficients at 5 degrees C ranged between 8.4 x 10(-12) (for ITX) and 5.1 x 10(-10) (for benzophenone) and those at 40 degrees C between 5.9 x 10(-10) (for ITX) and 6.1 x 10(-9) (for Irgacure 184). The diffusion coefficients of the six model migrants under study increased with temperature and showed a good Arrhenius relationship between 5 and 40 degrees C.
authors: Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Pharmacy, University of Santiago de Compostela, E-15782 Spain.
authors: Ana
authors: A
authors: Sanches-Silva
authors: Sarah
authors: S
authors: Pastorelli
authors: José M
authors: JM
authors: Cruz
authors: Catherine
authors: C
authors: Simoneau
authors: Isabel
authors: I
authors: Castanheira
authors: Perfecto
authors: P
authors: Paseiro-Losada
mesh_terms: D000818:Animals; D001577:Benzophenones / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D004058:Diffusion; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging; D005519:Food Preservation; D007281:Ink; D008892:Milk / Q000737:chemistry*; D008962:Models, Theoretical; D010777:Photochemistry; D015203:Reproducibility of Results; D013816:Thermodynamics; D044004:Xanthones / Q000737:chemistry
chemical_list: D001577:Benzophenones; D044004:Xanthones; C514852:isopropyl thioxanthone; C047723:benzophenone