title: In vitro antibiotic susceptibility of preoperative normal conjunctival bacteria.
abstract: OBJECTIVE
  To determine the antibiotic susceptibility of preoperative conjunctival bacterial flora.
  
  
  METHODS
  Antibiotic susceptibility of conjunctival bacterial strains isolated from 142 patients undergoing intraocular surgery was determined using the Kirby-Bauer disc diffusion technique. chi(2) statistical analysis was performed.
  
  
  RESULTS
  Among the 116 bacteria isolated, 95 (82%) were coagulase-negative staphylococci (CNS). Most (>75%) of them were susceptible to vancomycin, minocycline, aminoglycosides, gatifloxacin, levofloxacin, and moxifloxacin. Approximately one-half of CNS was resistant to erythromycin and azithromycin. Over 90% of streptococci were susceptible to levofloxacin, moxifloxacin, and gatifloxacin.
  
  
  RESULTS
  Fluoroquinolones, specifically gatifloxacin, levofloxacin, and moxifloxacin continue to provide broad-spectrum coverage against common conjunctival bacterial flora.
authors: Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA 94305, USA. cta@ stanford.edu
authors: C N
authors: CN
authors: Ta
authors: L
authors: L
authors: He
authors: H
authors: H
authors: Mino de Kaspar
mesh_terms: D000869:Anterior Eye Segment / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D019072:Antibiotic Prophylaxis; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D003228:Conjunctiva / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D015818:Eye Infections, Bacterial / Q000382:microbiology; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects / Q000302:isolation & purification; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones