Syncope as a probable side effect to combination antiretroviral therapy initiated during primary HIV-1 infection.
A previously healthy young man experienced several episodes of syncope while being treated with tenofovir, emtricitabine and nevirapine initiated during primary HIV-1 infection. Symptoms disappeared after discontinuation of antiretroviral therapy and we suggest that syncope may be a side effect to one of the three antiretroviral drugs that has not been described previously.
Lybaek
Dorte
D
Department of Infectious Diseases, Skejby Hospital, University Hospital of Aarhus, DK-8200 Aarhus N, Denmark. dlybaek@dadlnet.dk
Larsen
Carsten Schade
CS
D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives; D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000009:adverse effects*; D023241:Antiretroviral Therapy, Highly Active; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives; D000068679:Emtricitabine; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D019829:Nevirapine / Q000009:adverse effects; D063065:Organophosphonates / Q000009:adverse effects; D013575:Syncope / Q000139:chemically induced*; D000068698:Tenofovir
D019380:Anti-HIV Agents; D063065:Organophosphonates; D003841:Deoxycytidine; D019829:Nevirapine; D000068698:Tenofovir; D000068679:Emtricitabine; D000225:Adenine