[The frequency of some infections in patients with coronary artery disease].
The paper is dedicated to associations between infective agents and coronary artery disease (CAD). The study design included examination of a random sample of non-organized population (389 adults aged 25 to 64 years). Using immune-enzyme assay, IgM and IgG antibodies to seven infective and parasite agents (Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Trichomonas vaginalis, Candida albicans, Opisthorchis felineus, and Giardia lamblia), as well as the level of IgE were measured. In patients with CAD, IgE level was significantly higher vs. controls, but is was not connected with the infections under study except opisthorchosis invasion. The incidence of some pathogens was higher in CAD patients vs. controls. The total number of infections detected in an individual was associated with a higher frequency of CAD and some atherosclerotic risk factors.
Reshetnikov
O V
OV
Maliutina
S K
SK
Nikitin
Iu P
IuP
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D000908:Antibodies, Fungal / Q000032:analysis; D000913:Antibodies, Protozoan / Q000032:analysis; D001424:Bacterial Infections / Q000175:diagnosis / Q000453:epidemiology*; D003327:Coronary Disease / Q000150:complications*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D010272:Parasitic Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D012800:Siberia / Q000453:epidemiology
D000907:Antibodies, Bacterial; D000908:Antibodies, Fungal; D000913:Antibodies, Protozoan