title: Pseudotumor cerebri following tapered corticosteroid treatment in an 8-month-old infant.
abstract: The authors report on an 8-month-old infant with an orbital capillary hemangioma. The patient had been treated with high-dose corticosteroid therapy and had had a recent decrease in dose. The patient presented to the emergency department with increased irritability and bulging fontanelles. On lumbar puncture the opening pressure was > 55 cm H(2)O. Ophthalmological examination revealed interval development of papilledema. The child was treated with high-volume lumbar puncture, subsequent drainage of 10 ml of cerebrospinal fluid, resumption of the previous steroid dose, and acetazolomide therapy. The patient's symptoms resolved and follow-up ophthalmological examination revealed interval resolution of papilledema. The authors present the youngest reported case of pseudotumor development after corticosteroid tapering.
authors: Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
authors: Wilson Z
authors: WZ
authors: Ray
authors: Amy
authors: A
authors: Lee
authors: Spiros L
authors: SL
authors: Blackburn
authors: Gregg T
authors: GT
authors: Lueder
authors: Jeffrey R
authors: JR
authors: Leonard
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D018324:Hemangioma, Capillary / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods; D009918:Orbital Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D010211:Papilledema / Q000139:chemically induced; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D013396:Suction
chemical_list: D000893:Anti-Inflammatory Agents