Lewis acid-catalyzed hydrogenation: B(C6F5)3-mediated reduction of imines and nitriles with H2.
The Lewis acid B(C(6)F(5))(3) has been found to be an efficient catalyst for the direct hydrogenation of imines and the reductive ring-opening of aziridines with H(2) under mild conditions; addition of a bulky phosphine allows for the reduction of protected nitriles.
Chase
Preston A
PA
Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Ave. Windsor, Ontario, CanadaN9B 3P4. dstephan@chem.utoronto.ca.
Jurca
Titel
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Stephan
Douglas W
DW