title: Salmonella phages and prophages--genomics and practical aspects.
abstract: Numerous bacteriophages specific to Salmonella have been isolated or identified as part of host genome sequencing projects. Phylogenetic analysis of the sequenced phages, based on related protein content using CoreGenes, reveals that these viruses fall into five groupings (P27-like, P2-like, lambdoid, P22-like, and T7-like) and three outliers (epsilon15, KS7, and Felix O1). The P27 group is only represented by ST64B; the P2 group contains Fels-2, SopEphi, and PSP3; the lambdoid Salmonella phages include Gifsy-1, Gifsy-2, and Fels-1. The P22-like viruses include epsilon34, ES18, P22, ST104, and ST64T. The only member of the T7-like group is SP6. The properties of each of these phages are discussed, along with their role as agents of genetic exchange and as therapeutic agents and their involvement in phage typing.
authors: Host and Pathogen Determinants, Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, Guelph, Ontario.
authors: Andrew M
authors: AM
authors: Kropinski
authors: Alexander
authors: A
authors: Sulakvelidze
authors: Paulina
authors: P
authors: Konczy
authors: Cornelius
authors: C
authors: Poppe
mesh_terms: D000818:Animals; D017901:Bacteriophage P2 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D017100:Bacteriophage P22 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D001434:Bacteriophage Typing / Q000379:methods; D002240:Carbohydrate Sequence; D002874:Chromosome Mapping; D005516:Food Microbiology; D016679:Genome, Viral; D023281:Genomics / Q000379:methods*; D006801:Humans; D008969:Molecular Sequence Data; D019081:O Antigens / Q000235:genetics; D010802:Phylogeny; D039002:Prophages / Q000235:genetics*; D012475:Salmonella / Q000235:genetics / Q000276:immunology / Q000821:virology*; D012480:Salmonella Infections / Q000628:therapy; D012481:Salmonella Infections, Animal / Q000628:therapy; D012483:Salmonella Phages / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D017906:Siphoviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D014773:Virology / Q000379:methods
chemical_list: D019081:O Antigens