A new helper phospholipid for gene delivery.
Enhanced gene transfection activity is observed when using a new helper lipid with DOTAP, compared to DOPE.
Prata
Carla A H
CA
Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA 02215, USA.
Li
Yougen
Y
Luo
Dan
D
McIntosh
Thomas J
TJ
Barthelemy
Philippe
P
Grinstaff
Mark W
MW
D000818:Animals; D016466:CHO Cells; D002460:Cell Line; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000737:chemistry; D005229:Fatty Acids, Monounsaturated / Q000737:chemistry*; D018014:Gene Transfer Techniques; D006801:Humans; D015394:Molecular Structure; D010713:Phosphatidylcholines / Q000737:chemistry; D010714:Phosphatidylethanolamines / Q000737:chemistry*; D010743:Phospholipids / Q000737:chemistry* / Q000493:pharmacokinetics; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D014162:Transfection; D001616:beta-Galactosidase / Q000235:genetics / Q000378:metabolism
C410262:1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine; D005229:Fatty Acids, Monounsaturated; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D000644:Quaternary Ammonium Compounds; D004247:DNA; D001616:beta-Galactosidase; C017251:1,2-oleoylphosphatidylcholine; C070046:1,2-dioleoyloxy-3-(trimethylammonium)propane