title: Non-invasive pre-surgical investigation of a 10 year-old epileptic boy using simultaneous EEG-NIRS.
abstract: Near-infrared spectroscopy (NIRS) is a novel imaging technique of potential value in the pre-surgical investigation of patients with refractory epilepsy. We recorded simultaneously electrophysiology (EEG; Compumedics, USA) and near-infrared spectroscopy (NIRS; ISS, USA) to examine the localization of the ictal onset zone and assess language lateralization in a young epileptic boy (L.H., 10 years) as part of his pre-surgical evaluation. L.H. underwent a prolonged EEG-NIRS recording while electro-clinical and electrical seizures were recorded. Results were compared to those obtained with other pre-surgical techniques (SPECT, FDG-PET, EEG-fMRI and EEG-MEG) and showed good concordance for ictal onset zone localization. A second NIRS session without EEG was carried out in order to investigate language lateralization. For this purpose, the patient performed a categorical verbal-fluency task during NIRS recordings. Results showed left-hemisphere dominance for language function in this young boy. This case report illustrates that multi-channel EEG-NIRS has the potential to contribute favourably to pre-surgical investigation in young patients.
authors: Centre de Recherche en Neuropsychologie et Cognition, Université de Montréal, Département de Psychologie, Centre-Ville, Montréal, Québec, H3C 3J7, Canada.
authors: Anne
authors: A
authors: Gallagher
authors: Maryse
authors: M
authors: Lassonde
authors: Danielle
authors: D
authors: Bastien
authors: Phetsamone
authors: P
authors: Vannasing
authors: Frédéric
authors: F
authors: Lesage
authors: Christophe
authors: C
authors: Grova
authors: Alain
authors: A
authors: Bouthillier
authors: Lionel
authors: L
authors: Carmant
authors: Franco
authors: F
authors: Lepore
authors: Renée
authors: R
authors: Béland
authors: Dang Khoa
authors: DK
authors: Nguyen
mesh_terms: D002648:Child; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000097:blood / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D011182:Postoperative Care; D019265:Spectroscopy, Near-Infrared / Q000379:methods*