Clinical and investigative profile of biopsy-proven sarcoid uveitis in India.
OBJECTIVE
Retrospective analysis of the clinical features, investigative profile, response to treatment, and final visual outcome in histopathologically confirmed cases of sarcoid uveitis.


METHODS
Retrospective case series analysis was done of 15 eyes of 9 patients seen between July 1999 and August 2003 with biopsy-proven sarcoid uveitis. There were 3 were males and 6 females. The mean age at presentation was 44.1 years (range 11-62 years), The mean follow-up was 28.4 months.


RESULTS
Six patients had bilateral ocular involvement and 3 had unilateral involvement. Five out of 9 patients had primarily ocular involvement. The most common presentation was intermediate uveitis and granulomatous anterior uveitis in 7 patients. Eight of 9 patients responded well to the medical treatment with systemic and periocular steroids.


CONCLUSIONS
Ocular lesions can be the primary manifestation of systemic sarcoidosis. Sarcoid uveitis in the Asian Indian population often presents an intermediate uveitis with granulomatous anterior uveitis.
Ganesh
Sudha K
SK
Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, India. ganeshsugam@yahoo.com
Agarwal
Manisha
M
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D003315:Cornea / Q000473:pathology; D005123:Eye / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006099:Granuloma / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000209:etiology / Q000473:pathology; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome; D014605:Uveitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D014606:Uveitis, Anterior / Q000209:etiology / Q000473:pathology; D014785:Vision, Ocular / Q000187:drug effects
D013256:Steroids