Isolation of caprine herpesvirus 1 from a major outbreak of infectious pustular vulvovaginitis in goats.
We describe an outbreak of infectious pustular vulvovaginitis caused by Caprine herpesvirus 1 (CpHV1) in a group of approximately 200, 8 month old virgin does that were imported to Victoria from New Zealand. CpHV1 was isolated in cell cultures from vaginal swabs from three of three affected does but not from two bucks that had been with the does. The identity of the virus as a herpesvirus was confirmed by negative stain electron microscopy. Restriction endonuclease DNA fingerprint analysis showed that the DNA fingerprints were similar, but not identical, to previously described CpHV1 isolates made in New Zealand, New South Wales, and in other parts of the world. Acute and convalescent phase sera from selected does supported the diagnosis of CpHV1 infection. It is most likely that the disease was initiated by reactivation of latent virus in at least one of four bucks that served the does, since each was positive for CpHV neutralising antibody when first tested. This is the first report of CpHV infectious pustular vulvovaginitis in goats in Victoria and to our knowledge appears to be one of the largest outbreaks recorded anywhere.
Piper
K L
KL
Newborough Veterinary Centre, Newborough, Victoria.
Fitzgerald
C J
CJ
Ficorilli
N
N
Studdert
M J
MJ
D000822:Animal Husbandry; D000818:Animals; D004279:DNA, Viral / Q000032:analysis; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D015511:Goat Diseases / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D006041:Goats; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D018140:Varicellovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D014739:Victoria / Q000453:epidemiology; D014848:Vulvovaginitis / Q000453:epidemiology / Q000662:veterinary*
D004279:DNA, Viral