[Clinical and pathological features of synchronous double primary cancer in stomach and large intestine].
OBJECTIVE
To explore the clinical and pathological features of synchronous double primary cancer in stomach and large intestine.


METHODS
The clinical data of 35 patients with synchronous double primary cancer in stomach and large intestine out of 1117 patients with gastric and colorectal cancers treated during the period from January 2001 to December 2006, including 766 cases of colorectal cancer and 351 cases of gastric cancer, were analyzed.


RESULTS
The 35 patients of synchronous double primary cancer in stomach and large intestine, accounting for 3.13% of the cases of gastric and colorectal cancers, 23 males and 12 females, aged 66.7 (44 - 89), could be divided into 4 groups: intestine-intestine group (n = 15), stomach-stomach group (n = 3), intestine-extra-intestine group (n = 13), and stomach-extra-stomach group (n = 9); the last 2 groups included 5 case with their primary cancer located in stomach-and large intestine respectively. The number of cases with the 2 primary carcinoma foci both located in the entero-intestinal duct, stomach and large intestine, was 23, more than that of the cases with their 2 carcinoma foci located in stomach or large intestine and other organs respectively (n = 12). The 3-year survival rate of the large intestine-large intestine group was higher than that of the stomach-stomach group.


CONCLUSIONS
Early diagnosis, correct distinguishing of the primary and metastatic cancer play an important role in the treatment of synchronous double primary cancer and improvement of the prognosis.
Shen
Zhan-Long
ZL
Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing 100044, China.
Wang
Shan
S
Ye
Ying-Jiang
YJ
Yin
Mu-Jun
MJ
Yang
Xiao-Dong
XD
Jiang
Ke-Wei
KW
Shen
Kai
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology*; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology*