Drinking influences exhaled breath condensate acidity.
Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensate, capillary blood, and urine of 12 healthy volunteers were collected before and after drinking either 1 l of coke or 1 l of mineral water. The pH of each sample was determined with a blood gas analyzer. The mean difference between the pH of two breath condensate samples collected within 15 min before drinking was 0.13+/-0.03. Condensate pH decreased significantly from 6.29+/-0.02 to 6.24+/-0.02 (p<0.03) after drinking coke and from 6.37+/-0.03 to 6.22+/-0.04 (p<0.003) after drinking water. Drinking coke induced significant changes in blood and urine pH as well. Drinking influences exhaled breath condensate composition and may contribute to the variability of exhaled breath condensate pH.
Kullmann
Tamás
T
Department of Pathophysiology, National Korányi Institute for TB and Pulmonology, Pihenő u. 1, Budapest, 1529, Hungary. kullmanndoki@hotmail.com.
Barta
Imre
I
Department of Pathophysiology, National Korányi Institute for TB and Pulmonology, Pihenő u. 1, Budapest, 1529, Hungary.
Antus
Balázs
B
Department of Pathophysiology, National Korányi Institute for TB and Pulmonology, Pihenő u. 1, Budapest, 1529, Hungary.
Horváth
Ildikó
I
Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary.
D000136:Acid-Base Equilibrium; D000293:Adolescent; D000328:Adult; D001628:Beverages; D015415:Biomarkers / Q000097:blood / Q000378:metabolism* / Q000652:urine; D001774:Blood Chemical Analysis; D001944:Breath Tests; D002021:Buffers; D002245:Carbon Dioxide; D045853:Exhalation; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016482:Urinalysis; D055815:Young Adult
D015415:Biomarkers; D002021:Buffers; D002245:Carbon Dioxide