Endogenous retroviruses of the chicken genome.
We analyzed the chicken (Gallus gallus) genome sequence to search for previously uncharacterized endogenous retrovirus (ERV) sequences using ab initio and combined evidence approaches. We discovered 11 novel families of ERVs that occupy more than 21 million base pairs, approximately 2%, of the chicken genome. These novel families include a number of recently active full-length elements possessing identical long terminal repeats (LTRs) as well as intact gag and pol open reading frames. The abundance and diversity of chicken ERVs we discovered underscore the utility of an approach that combines multiple methods for the identification of interspersed repeats in vertebrate genomes.
Huda
Ahsan
A
School of Biology, Georgia Institute of Technology, Atlanta, GA, USA. ahsan.huda@gatech.edu
Polavarapu
Nalini
N
Jordan
I King
IK
McDonald
John F
JF
D000818:Animals; D002645:Chickens / Q000235:genetics* / Q000821:virology*; D019295:Computational Biology; D020077:Endogenous Retroviruses / Q000737:chemistry / Q000235:genetics*; D016678:Genome; D006801:Humans; D005810:Multigene Family; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D012984:Software; D020079:Terminal Repeat Sequences