[The efficacy of the ultrashort-term action insulin-lispro preparation "humalog" and the antioxidant mexidol in the complex treatment of type I diabetes in infants and adolescents].
Monitoring of a group of 96 children with type I diabetes mellitus showed the positive effect of fast-acting insulin analog humalog on the long-term glycemic control and correction of metabolic disturbances in the vegetative nervous system and on the elimination of psychological problems. Additional prescription of the antioxidant drug mexidol promoted restoration of the cardiac rhythm variability, normalization of a daily structure of the heart rate, improvement of memory and attention and decreased the level of anxiety. The observations showed a decrease in the rate of formation of the diabetic cardiac neuropathy and a reduction of expressiveness of cerebroasthenic syndrome.
Masiagina
E N
EN
Balykova
L A
LA
Mukhina
L Iu
LIu
Markelova
I A
IA
D000293:Adolescent; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy; D001288:Attention / Q000187:drug effects / Q000502:physiology; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007328:Insulin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D061268:Insulin Lispro; D008297:Male; D008568:Memory / Q000187:drug effects / Q000502:physiology; D010847:Picolines / Q000008:administration & dosage / Q000627:therapeutic use*
D000975:Antioxidants; D007004:Hypoglycemic Agents; D007328:Insulin; D061268:Insulin Lispro; D010847:Picolines; C070020:emoxypine succinate