title: Lack of effect of aerobic physical exercise on endothelium-derived nitric oxide concentrations in healthy young subjects.
abstract: Previous experimental research showed an attenuated vasoconstrictor response after acute exercise. This study aims to determine the effect of aerobic physical exercise on the endothelium-derived circulating nitric oxide (NO) concentrations among healthy young persons. A total of 10 subjects (5 men and 5 women) aged 21-28 were examined for the difference in concentrations of serum and plasma NO metabolites (NOx) before and after a single bout of aerobics, in which they performed cycling exercises at a constant workload corresponding to 90% of the subject-specific anaerobic threshold. A paired t-test resulted in no statistically significant differences between pre- and post-exercise concentrations of serum or plasma NOx. It is suggested that the acute effect of aerobic exercise on the vasoconstrictor/vasodilator response is not mediated by an increase in the endothelial NO release.
authors: Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Japan.
authors: Kanami
authors: K
authors: Yamamoto
authors: Takaaki
authors: T
authors: Kondo
authors: Akiko
authors: A
authors: Kimata
authors: Jun
authors: J
authors: Ueyama
authors: Aya
authors: A
authors: Shirotori
authors: Yoshiko
authors: Y
authors: Okada
authors: Daisuke
authors: D
authors: Sakui
authors: Masahiro
authors: M
authors: Nakashima
authors: Sumio
authors: S
authors: Yamada
mesh_terms: D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology*; D004730:Endothelium, Vascular / Q000378:metabolism*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism*; D014661:Vasoconstriction / Q000502:physiology
chemical_list: D009569:Nitric Oxide