title: Thyroid storm caused by a partial hydatidiform mole.
abstract: Clinical thyrotoxicosis is rare in molar pregnancy and has yet to be reported in a patient with a partial mole. Human chorionic gonadotropin (hCG), which has thyrotropic activity, is believed to be responsible for hyperthyroidism of gestational trophoblastic activity and hyperemesis gravidarum. We report the first case of hyperthyroidism presenting as thyroid storm in a partial molar pregnancy. Normal thyroid function returned after the partial mole was evacuated, and the biochemical improvement correlated with declining hCG levels. This case highlights the importance of including partial mole in the differential of hCG-mediated hyperthyroidism.
authors: Department of Medicine, Crozer Chester Medical Center, Upland, Pennsylvania 19013, USA. niyatichiniwala@gmail.com
authors: Niyati U
authors: NU
authors: Chiniwala
authors: Paul D
authors: PD
authors: Woolf
authors: Christopher P
authors: CP
authors: Bruno
authors: Sukhjinder
authors: S
authors: Kaur
authors: Harvey
authors: H
authors: Spector
authors: Kelli
authors: K
authors: Yacono
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000378:metabolism; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications / Q000175:diagnosis*; D006980:Hyperthyroidism / Q000150:complications / Q000175:diagnosis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D013958:Thyroid Crisis / Q000150:complications / Q000175:diagnosis*; D013961:Thyroid Gland / Q000473:pathology*; D013974:Thyroxine / Q000378:metabolism; D016896:Treatment Outcome; D014284:Triiodothyronine / Q000378:metabolism; D014327:Trophoblasts / Q000378:metabolism
chemical_list: D006063:Chorionic Gonadotropin; D014284:Triiodothyronine; D013974:Thyroxine