[Amyloidosis--life threatening complication in rheumatoid arthritis patients].
Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease leading to severe disability. A secondary amyloidosis (AA amyloidosis) affecting RA patient is a life threatening clinical complication of the illness. The most common symptoms of secondary amyloidosis include: proteinuria, erythrocyturia, abdominal pain and chronic diarrhoea. It is essential to carry out regular screening tests, especially abdominal fat tissue biopsy, to early diagnose and properly manage patients with the condition. Effective anti-inflammatory therapy of RA and eradication of coexisting infections seem to be the best way to decrease the risk of development and prevent progression of the secondary amyloidosis.
Trefler
Jakub
J
Klinki Chorób Reumatycznych, Instytutu Reumatologii w Warszawie. jakub.trefler@wp.pl
Matyska-Piekarska
Ewa
E
Wagner
Teresa
T
Łacki
Jan K
JK
D050153:Abdominal Fat / Q000473:pathology; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001706:Biopsy; D006801:Humans; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents