[Efficacy of guided ovarian hyperstimulation in patients with mild type endometriosis].
OBJECTIVE
Endometriosis befalls in one of the most frequent gynecologic diseases. It manifests itself by the presence and growth of focus of endometrium out of the uterus cavum that reacts to hormonal stimulations as the normal uterus endometrium does. Hyperstimulation and induction of ovulation together with intrauterine insemination (IUI) are the most frequently used treatments of unexplained infertility in patients with mild type endometriosis. The aim of this study was to compare the effects of stimulation using human meno pausal gonadotrophine (hMG) in the patients with mild type endometriosis to the patients with infertility of unknown ethiology.


METHODS
The study included 50 patients with unexplained infertility (group N), as well as 50 patients with mild type endometriosis (group E) confirmed by laparoscopy. Within the same therapeutic protocole hIMG stimulation and horionic gonadotrophine induction (hCG) were used.


RESULTS
In the group E ovulation occurred in 74% of the pa tients during the first stimulation, in 77.78% during the second cycle, and in 75% of the patients during the third one. Regarding the group N, ovulation appeared in 82% of the patients during the first stimulation. Stimulation was performed two times more in 38 patients with unknown couse of infertil ity, and ovulation appeared in 84.21 percent of them. In the group N stimulation was performed three times in 28 women resulting in ovulation in 85.71% of them.


CONCLUSIONS
Con sidering the obtained results it can be concluded that hMG stimulation and hCG induction are efficient in the treatment of infertility, particularly in mild type endometriosis.
Jasović-Siveska
Emilija
E
Univerzitet Sveti Kliment Ohridski, Visoka medicinska skola, Bitola, Makedonija. medihelp@mt.net.mk
Jasović
Vladimir
V
D000328:Adult; D006063:Chorionic Gonadotropin / Q000008:administration & dosage*; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D008596:Menotropins / Q000008:administration & dosage* / Q000627:therapeutic use; D010062:Ovulation Induction; D011247:Pregnancy
D006063:Chorionic Gonadotropin; D008596:Menotropins