title: [Drug rehabilitation in stroke patients].
abstract: An influence of different drugs on functional rehabilitation in post-stroke patients has been studied. We tested for efficacy medications with nootropic, metabolic and antioxidative activity as well as pathogenetic and symptomatic remedies for differential therapy of ischemic and haemorrhagic stroke (IS, HS). We analyzed 1920 stroke patients, including 1520 with IS and 400 with HS. The functional rehabilitation depending on different drugs was followed up 1 year after stroke using Barthel, Lindmark and Scandinavian scales for stroke. Moreover, we suggested a coefficient for calculating of drug efficacy. The results of the study revealed that the use of some traditional drugs was not well founded. The most efficient medications in the treatment of IS proved to be actovegin, instenon, berlition, rheopolyglucin and gliatilin. The beneficial effect on rehabilitation of patients with HS was found only for actovegin.
authors: A A
authors: AA
authors: Skoromets
authors: V V
authors: VV
authors: Koval'chuk
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006418:Heme / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D000697:Central Nervous System Stimulants; D006418:Heme; C015646:Actovegin