title: Current neurosurgical management of brain metastases.
abstract: Brain metastases occur in a third of patients diagnosed with cancer; without any intervention, the prognosis is quite poor with a median survival of 1 month. Because of the constraints of the blood-brain barrier, chemotherapy is not effective and treatment options include surgery, whole brain radiation, or stereotactic radiation. This chapter is devoted to a review of the current management options for treatment of brain metastases.
authors.affiliation: Department of Neurosurgery, Thomson Jefferson University, Jefferson Medical College, Philadelphia, PA 19107, USA. david.andrews@jefferson.edu
authors.forename: David W
authors.initials: DW
authors.lastname: Andrews
mesh_terms: D001812:Blood-Brain Barrier; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy*; D006801:Humans; D019635:Neurosurgical Procedures; D011379:Prognosis; D016634:Radiosurgery