Diastereoselective synthesis of enantiopure acyclic beta,beta'-disubstituted vinylsulfoxides.
Thermal elimination of sulfenic acid from enantiopure beta,beta'-disubstituted bis-sulfoxides allows the stereoselective synthesis of enantiopure acyclic beta,beta'-disubstituted vinylsulfoxides. This mild and stereospecific synthesis provides either ( E) or ( Z) vinylsulfoxides in high yields and is compatible with acid or base sensitive functional groups.
Brebion
Franck
F
UPMC- Univ. Paris 06, Laboratoire de Chimie Organique, UMR 7611, Institut de Chimie Moléculaire, FR 2769, case 229, 4 place Jussieu, 75252 Paris Cedex 05, France.
Goddard
Jean-Philippe
JP
Fensterbank
Louis
L
Malacria
Max
M
D008968:Molecular Conformation; D013237:Stereoisomerism; D013454:Sulfoxides / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
D013454:Sulfoxides