title: Multiple pilomatrixomas affecting the eyelid and face.
abstract: A 3-year-old girl presented with a right upper eyelid mass. The lesion had a reddish appearance, was firm to palpation, and was fixed to underlying tissues. Fourteen months after the lesion was excised, a similar lesion was discovered on the left side of the nose and was also excised. Histopathologic examination of the excised tumors revealed variable basophilic hair matrix cells and sheets of nonviable eosinophilic shadow cells. Foci of dystrophic calcification were also seen in the necrotic tumor areas. The histopathologic findings were found to be consistent with pilomatrixoma. Results of limited clinical work-up of the child for Gardner's syndrome, sarcoidosis, and myotonic dystrophy were negative. Multiple periocular and facial pilomatrixomas can occur in children in the clinical absence of myotonic dystrophy, Gardner's syndrome, and sarcoidosis.
authors.affiliation: Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Kaan
authors.initials: K
authors.lastname: Gündüz
authors.forename: Mahmut
authors.initials: M
authors.lastname: Ecel
authors.forename: Esra
authors.initials: E
authors.lastname: Erden
mesh_terms: D002675:Child, Preschool; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005153:Facial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018296:Pilomatrixoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed