A comprehensive survey of cadherin superfamily gene expression patterns in Ciona intestinalis.
We have carried out a comprehensive survey of the spatiotemporal expression of cadherin superfamily genes in the basal chordate Ciona intestinalis, as an example of a genome-wide expression study of a gene family directly regulating cellular processes in morphogenesis. We found 15 definitely expressed cadherin superfamily genes in the Ciona intestinalis genome. Up to the late gastrula stage, all identified delta-protocadherins and the type II classical cadherin, but not other subfamily members, were zygotically expressed. At later stages, however, all cadherin superfamily genes were expressed in the nervous system. These data are useful for understanding the role of these genes in Ciona development and the evolution of chordates.
Noda
Takeshi
T
Department of Zoology, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan. noda@ascidian.zool.kyoto-u.ac.jp
Satoh
Nori
N
D000818:Animals; D015820:Cadherins / Q000235:genetics / Q000378:metabolism*; D002938:Ciona intestinalis / Q000196:embryology / Q000235:genetics / Q000378:metabolism*; D030541:Databases, Genetic; D004625:Embryo, Nonmammalian; D005775:Gastrula / Q000378:metabolism; D015870:Gene Expression; D016678:Genome; D017403:In Situ Hybridization; D008957:Models, Genetic; D054258:Neural Plate / Q000378:metabolism; D010802:Phylogeny
D015820:Cadherins