title: Aurocitrin and related polyketide metabolites from the wood-decay fungus Hypocrea sp. BCC 14122.
abstract: The known gentisaldehyde antibiotic aurocitrin (1), its cis-olefinic isomer (2), a salicylaldehyde analogue (3), two new benzofuran derivatives (4 and 5), and a new dihydroisocoumarin (6) were isolated from the wood-decay fungus Hypocrea sp. BCC 14122. The structures were elucidated primarily by NMR and mass spectroscopic analyses.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
authors.forename: Pitchapa
authors.initials: P
authors.lastname: Berkaew
authors.forename: Noppamas
authors.initials: N
authors.lastname: Soonthornchareonnon
authors.forename: Kitlada
authors.initials: K
authors.lastname: Salasawadee
authors.forename: Rungtiwa
authors.initials: R
authors.lastname: Chanthaket
authors.forename: Masahiko
authors.initials: M
authors.lastname: Isaka
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D002522:Chlorocebus aethiops; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D035901:Hypocrea / Q000737:chemistry*; D007624:KB Cells; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular; D010963:Plasmodium falciparum / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism; D014709:Vero Cells; D014934:Wood / Q000382:microbiology
chemical_list: D000447:Aldehydes; D000962:Antimalarials; D000970:Antineoplastic Agents; D001572:Benzofurans; D003374:Coumarins; C530242:aurocitrin