title: Pressure profile in the caudal extradural space of standing horses before and after extradural drug administration.
abstract: The objectives of this study were to measure the pressure in the caudal extradural space of standing horses and to evaluate the usefulness of pressure waves to identify correct needle placement. Caudal extradural pressure was measured in 12 healthy horses. The pressure and any extradural pressure waves were recorded for 3min after puncture, for 1min after testing for lack of resistance (LOR), and for 10min after lidocaine injection. Successful extradural drug administration was confirmed in all horses. The median extradural pressure findings after puncture, after LOR, immediately after injection and 10min after needle placement were -1.60kPa (range -2.27 to 1.33kPa), -0.67kPa (-2.27 to 5.73kPa), 5.00kPa (0.93 to 9.87kPa) and 0.13kPa (-0.67 to 4.53kPa), respectively. Extradural pressure waves were not always present. Extradural space pressure was sub-atmospheric in most horses and extradural injection significantly increased this pressure for up to 10min. Extradural pressure waves had limited usefulness in the confirmation of the correct placement of the needle.
authors.affiliation: Clinic for Anaesthesiology and Perioperative Intensive Care, Clinical Department of Small Animals and Horses, Veterinary University, Vienna, Austria. i.iff@liv.ac.uk
authors.forename: Isabelle
authors.initials: I
authors.lastname: Iff
authors.forename: Martina
authors.initials: M
authors.lastname: Mosing
authors.forename: Yves
authors.initials: Y
authors.lastname: Moens
mesh_terms: D000767:Anesthesia, Epidural / Q000379:methods / Q000662:veterinary*; D000779:Anesthetics, Local / Q000008:administration & dosage; D000818:Animals; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology*; D004824:Epidural Space / Q000502:physiology; D005260:Female; D006736:Horses / Q000502:physiology* / Q000601:surgery; D007268:Injections, Epidural / Q000662:veterinary*; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D011312:Pressure
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine