Clinical features of syndromic craniosynostosis.
Disruption of normal suture development and function can result in premature suture fusion, craniosynostosis. This review focuses on syndromic forms of craniosynostosis. More than 100 syndromes in which craniosynostosis is a feature have been documented and here the most common conditions including Apert and Crouzon syndromes are described as well as other conditions with a particularly interesting molecular etiology, such as Saethre- Chotzen and craniofrontonasal syndrome.
Rice
David P
DP
Departments of Orthodontics and Craniofacial Development, King's College London, London, UK; Department of Orthodontics, University of Helsinki, Helsinki, Finland.
D000168:Acrocephalosyndactylia / Q000145:classification / Q000175:diagnosis; D003394:Craniofacial Dysostosis / Q000175:diagnosis; D003398:Craniosynostoses / Q000175:diagnosis*; D005624:Frontal Bone / Q000002:abnormalities; D006801:Humans; D009295:Nasal Bone / Q000002:abnormalities; D010294:Parietal Bone / Q000002:abnormalities; D013577:Syndrome; D013796:Thanatophoric Dysplasia / Q000175:diagnosis