[Pulmonary metastasis of fibrosarcomatous variant of dermatofibrosarcoma protuberans: case report and review of literature].
A 63-year-old man had undergone excision of a growing mass with a wide margin in the left supraclavicular fossa. A diagnosis of fibrosarcomatous variant of dermatofibrosarcoma protuberans (DFSP-FS) was made. Three years later, an abnormal chest shadow was detected on a medical checkup. Chest computed tomography showed a heterogeneously-enhanced 2-cm coin lesion with a distinct border in the right lower lobe and a 3-mm nodule in the left lower lobe. Transbronchial lung biopsy specimens from the right lung revealed a DFSP pattern. We then performed right basal segmentectomy and partial resection of the left lower lobe. DFSP is a relatively rare skin tumor that is considered to be intermediate malignancy. It frequently recurs locally but rarely has systemic metastasis. However, DFSP-FS, a subtype of DFSP, has an increased likelihood of systemic metastasis. The lung is the most common site of metastasis of DFSP-FS. DFSP-FS sometimes recurs even a long time after excision. Therefore, long-term follow-up, including chest X-ray and CT are important in DFSP-FS patients.
Otani
Satoshi
S
Department of Infectious Diseases, Oita University Faculty of Medicine.
Ishii
Hiroshi
H
Hashinaga
Kazuhiko
K
Morinaga
Ryotaro
R
Umeki
Kenji
K
Kishi
Kenji
K
Shirai
Ryo
R
Tokimatsu
Issei
I
Hiramatsu
Kazufumi
K
Kawahar
Katsunobu
K
Kadota
Jun-ichi
J
D018223:Dermatofibrosarcoma / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*