title: Multiple intracranial tuberculomas associated with partial status epilepticus and refractory infantile spasms.
abstract: We report the case of a 10 month-old girl presenting with multiple intracranial tuberculomas associated with partial status epilepticus and cerebrovascular accident in the left sylvian territory. She later developed paradoxical enlargement of the tuberculomas during antituberculous treatment and severe neurological sequelae with refractory infantile spasms. The development of infantile spasms in this context is particularly remarkable, and this case is illustrative of the complex interrelationship between intracranial lesions, partial status epilepticus, and infantile spasms. It also highlights the difficult diagnosis of cerebral tuberculomas in infants and further supports the need for continued vigilance in industrialized countries.
authors.affiliation: Department of Pediatrics, Strasbourg-Hautepierre University Hospital, Strasbourg, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Zorn-Olexa
authors.forename: Vincent
authors.initials: V
authors.lastname: Laugel
authors.forename: Anne de Saint
authors.initials: Ade S
authors.lastname: Martin
authors.forename: Lionel
authors.initials: L
authors.lastname: Donato
authors.forename: Michel
authors.initials: M
authors.lastname: Fischbach
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D013036:Spasms, Infantile / Q000150:complications* / Q000175:diagnosis; D013226:Status Epilepticus / Q000150:complications* / Q000175:diagnosis; D016862:Tuberculoma, Intracranial / Q000150:complications* / Q000175:diagnosis