title: Effect of N-terminal tripeptides of bombesin, litorin, and their analogue on body temperature and vasomotor responses.
abstract: Intranasal administration of bombesin caused hypothermia in rats maintained under cold conditions. N-terminal tripeptide of bombesin exhibits intrinsic vasomotor activity, while intranasal administration of its modified analogue produced a more potent hypothermic effect than intranasal bombesin.
authors.affiliation: N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow. emel@chph.ras.ru
authors.forename: T G
authors.initials: TG
authors.lastname: Emel'yanova
authors.forename: I V
authors.initials: IV
authors.lastname: Sosnovskaya
authors.forename: L S
authors.initials: LS
authors.lastname: Guzevatych
authors.forename: N N
authors.initials: NN
authors.lastname: Gorjacheva
authors.forename: T A
authors.initials: TA
authors.lastname: Voronina
authors.forename: E B
authors.initials: EB
authors.lastname: Evstigneeva
authors.forename: V P
authors.initials: VP
authors.lastname: Golubovich
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001831:Body Temperature / Q000187:drug effects*; D001839:Bombesin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology*; D007036:Hypothermia, Induced; D008297:Male; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology*; D010446:Peptide Fragments / Q000494:pharmacology; D051381:Rats; D014661:Vasoconstriction / Q000187:drug effects; D014666:Vasomotor System / Q000187:drug effects*
chemical_list: D009842:Oligopeptides; D010446:Peptide Fragments; C010212:litorin; D001839:Bombesin