title: Diastereoselective synthesis of enantiopure acyclic beta,beta'-disubstituted vinylsulfoxides.
abstract: Thermal elimination of sulfenic acid from enantiopure beta,beta'-disubstituted bis-sulfoxides allows the stereoselective synthesis of enantiopure acyclic beta,beta'-disubstituted vinylsulfoxides. This mild and stereospecific synthesis provides either ( E) or ( Z) vinylsulfoxides in high yields and is compatible with acid or base sensitive functional groups.
authors.affiliation: UPMC- Univ. Paris 06, Laboratoire de Chimie Organique, UMR 7611, Institut de Chimie Moléculaire, FR 2769, case 229, 4 place Jussieu, 75252 Paris Cedex 05, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Brebion
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Goddard
authors.forename: Louis
authors.initials: L
authors.lastname: Fensterbank
authors.forename: Max
authors.initials: M
authors.lastname: Malacria
mesh_terms: D008968:Molecular Conformation; D013237:Stereoisomerism; D013454:Sulfoxides / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
chemical_list: D013454:Sulfoxides