title: The prevalence, anatomical correlates and treatment of sleep-disordered breathing in obese children and adolescents.
abstract: The prevalence of childhood obesity is increasing worldwide. One of the obesity-related complications that has received increasing attention in recent years is sleep-disordered breathing. Obese children are at a higher risk of developing sleep-disordered breathing, including habitual snoring, obstructive sleep apnea syndrome and desaturations preceded by central apneas. Both adiposity and upper airway factors, such as adenotonsillar hypertrophy, modulate the severity of sleep-disordered breathing in these children. Adenotonsillectomy seems to be effective against obstructive sleep apnea syndrome in obese children. On the other hand, there are limited data on the effects of weight loss and of treatment with continuous positive airway pressure on the severity of sleep apnea in obese children and adolescents.
authors.affiliation: Department of Pediatrics, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium.
authors.forename: Stijn L
authors.initials: SL
authors.lastname: Verhulst
authors.forename: Luc
authors.initials: L
authors.lastname: Van Gaal
authors.forename: Wilfried
authors.initials: W
authors.lastname: De Backer
authors.forename: Kristine
authors.initials: K
authors.lastname: Desager
mesh_terms: D000234:Adenoids / Q000473:pathology / Q000503:physiopathology; D000293:Adolescent; D002648:Child; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks; D006801:Humans; D006984:Hypertrophy; D009765:Obesity / Q000453:epidemiology* / Q000503:physiopathology; D014066:Palatine Tonsil / Q000473:pathology / Q000503:physiopathology; D012307:Risk Factors; D020182:Sleep Apnea, Central / Q000453:epidemiology* / Q000503:physiopathology; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology* / Q000503:physiopathology; D012913:Snoring / Q000453:epidemiology / Q000503:physiopathology