Insulin in the brain what is its role?
Insulin and insulin receptors are present in brain and appear to function outside the realm of glucose homeostasis. Insulin receptors in the brain are structurally unique and appear to be found exclusively on neurons. Evidence from a variety of experimental systems indicates that insulin plays a role in neuronal growth and differentiation; additional functions may exist in the adult brain. Insulin action in neurons may be associated with unique signal transduction pathways.
Heidenreich
K A
KA
Department of Medicine, M-023E, Division of Endocrinology and Metabolism, University of California at San Diego, La Jolla, CA 92093, USA.