title: The solvent-free synthesis of 1,4-dihydropyridines under ultrasound irradiation without catalyst.
abstract: The condensation of aldehydes, ethyl acetoacetate and ammonium acetate result 1,4-dihydropyridines in 82-99% yields under ultrasound irradiation without solvent and catalyst at room temperature. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction time and higher yields.
authors.affiliation: Laboratory of Chemical Biology, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, PR China. wsx@mail.hbu.edu.cn
authors.forename: Shu-Xiang
authors.initials: SX
authors.lastname: Wang
authors.forename: Zhi-Yan
authors.initials: ZY
authors.lastname: Li
authors.forename: Jin-Chao
authors.initials: JC
authors.lastname: Zhang
authors.forename: Ji-Tai
authors.initials: JT
authors.lastname: Li
mesh_terms: D002384:Catalysis; D002853:Chromatography, Liquid; D004095:Dihydropyridines / Q000138:chemical synthesis*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D014465:Ultrasonics
chemical_list: D004095:Dihydropyridines; C038806:1,4-dihydropyridine