title: Endoscopic band ligation and endoscopic hemoclip placement for patients with Mallory-Weiss syndrome and active bleeding.
abstract: OBJECTIVE
  To compare the hemostatic efficacy and safety of two mechanical endoscopic methods: endoscopic band ligation (EBL) and endoscopic hemoclip placement (EHP) in patients with actively bleeding Mallory-Weiss syndrome (MWS).
  
  
  METHODS
  A prospective randomized study to compare the efficacy and safety of EHP with EBL was performed from January 2002 to August 2005. Forty-one patients with active bleeding from MWS were treated with EHP (n = 21) or EBL (n = 20).
  
  
  RESULTS
  There were no significant differences between groups with respect to clinical and endoscopic characteristics. The mean number of hemoclips applied was 3.2 +/- 1.5 and the mean number of bands applied was 1.2 +/- 0.4. Primary hemostasis was achieved in all patients. Recurrent bleeding was observed in one patient from the EHP group and two from the EBL group. Patients with recurrent bleeding were treated by the same modality as at randomization and secondary hemostasis was achieved in all. There were no significant differences between the two groups in total transfusion amount or duration of hospital stay. No complications or bleeding-related death resulted.
  
  
  CONCLUSIONS
  EHP and EBL are equally effective and safe for the management of active bleeding in patients with Mallory-Weiss syndrome, even in those with shock or comorbid diseases.
authors.affiliation: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Uijeongbu 480-717, Korea.
authors.forename: Young-Seok
authors.initials: YS
authors.lastname: Cho
authors.forename: Hiun-Suk
authors.initials: HS
authors.lastname: Chae
authors.forename: Hyung-Keun
authors.initials: HK
authors.lastname: Kim
authors.forename: Jin-Soo
authors.initials: JS
authors.lastname: Kim
authors.forename: Byung-Wook
authors.initials: BW
authors.lastname: Kim
authors.forename: Sung-Soo
authors.initials: SS
authors.lastname: Kim
authors.forename: Sok-Won
authors.initials: SW
authors.lastname: Han
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Choi
mesh_terms: D000328:Adult; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005762:Gastroenterology / Q000295:instrumentation / Q000379:methods; D006439:Hemodynamics; D006470:Hemorrhage / Q000628:therapy*; D016558:Hemostasis, Endoscopic / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008297:Male; D008309:Mallory-Weiss Syndrome / Q000601:surgery* / Q000628:therapy*; D008875:Middle Aged; D011446:Prospective Studies; D013525:Surgical Instruments; D013514:Surgical Procedures, Operative / Q000379:methods; D016896:Treatment Outcome