title: [Application of BED-CEIA to estimate the human immunodeficiency virus prevalence among injecting drug users in Chongqing municipality].
abstract: OBJECTIVE
  To estimate the human immunodeficiency virus (HIV-1) prevalence of injecting drug users (IDUs) in Chongqing city.
  
  
  METHODS
  To apply BED-capture enzyme immunoassay (CEIA) which was based on the principle of HIV-antibody varies as the disease progress, in order to estimate both the HIV incidence and prevalence of IDUs from two IDUs surveillance sites in Chongqing.
  
  
  RESULTS
  During the research period, 4711 serum samples were tested by ELISA and 130 were HIV-1 positive, confirmed by Western blot. The prevalence of IDUs surveillance site A from 1999 to 2006 were 0.73%, 2.02%, 1.54%, 2.96% and 2.80%, and the incidence rates were 0.57%, 0.93%, 0,1.24% and 1.68% respectively. The prevalence of IDUs surveillance site B appeared to be 4.21%, 9.96%, 8.13%, and the incidence rates were 0.95%, 1.04% and 0.90% respectively, from 2004 to 2006.
  
  
  CONCLUSIONS
  Many of the IDUs HIV carriers in Chongqing had been infected for long time, and the incidence rates among them were steady, keeping at the same level for 1-2 years. Promotion on intervention for IDUs had produced certain effects but more attention still needs to be paid.
authors.affiliation: Chongqing Center for Disease Control and Prevention, Chongqing 400042, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Han
authors.forename: Yu-lin
authors.initials: YL
authors.lastname: Wang
authors.forename: Min-jie
authors.initials: MJ
authors.lastname: Wang
authors.forename: Quan-hua
authors.initials: QH
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
mesh_terms: D015492:AIDS Serodiagnosis / Q000379:methods*; D002681:China / Q000453:epidemiology; D055030:Drug Users; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology*; D015528:HIV Seroprevalence; D006801:Humans; D007124:Immunoenzyme Techniques; D015994:Incidence; D011159:Population Surveillance; D015995:Prevalence; D015819:Substance Abuse, Intravenous / Q000453:epidemiology / Q000821:virology*; D014505:Urban Population / Q000706:statistics & numerical data
chemical_list: D015483:HIV Antibodies