title: Neuroinvasion by Mycoplasma pneumoniae in acute disseminated encephalomyelitis.
abstract: We report the autopsy findings for a 45-year-old man with polyradiculoneuropathy and fatal acute disseminated encephalomyelitis after having Mycoplasma pneumoniae pneumonia. M. pneumoniae antigens were demonstrated by immunohistochemical analysis of brain tissue, indicating neuroinvasion as an additional pathogenetic mechanism in central neurologic complications of M. pneumoniae infection.
authors.affiliation: Kantonsspital Aarau, Aarau, Switzerland. stamm@ksa.ch
authors.forename: Bernhard
authors.initials: B
authors.lastname: Stamm
authors.forename: Michael
authors.initials: M
authors.lastname: Moschopulos
authors.forename: Hansjoerg
authors.initials: H
authors.lastname: Hungerbuehler
authors.forename: Jeannette
authors.initials: J
authors.lastname: Guarner
authors.forename: Gillian L
authors.initials: GL
authors.lastname: Genrich
authors.forename: Sherif R
authors.initials: SR
authors.lastname: Zaki
mesh_terms: D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000097:blood / Q000134:cerebrospinal fluid; D000942:Antigens, Bacterial / Q000302:isolation & purification; D001921:Brain / Q000382:microbiology / Q000473:pathology; D004679:Encephalomyelitis / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009177:Mycoplasma pneumoniae / Q000276:immunology / Q000302:isolation & purification*; D011019:Pneumonia, Mycoplasma / Q000150:complications*; D011129:Polyradiculoneuropathy / Q000150:complications / Q000382:microbiology* / Q000473:pathology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial