Novel parameters of surface EMG in patients with Parkinson's disease and healthy young and old controls.
The aim of this study was to evaluate a variety of traditional and novel surface electromyography (SEMG) characteristics of biceps brachii muscle in patients with Parkinson's disease (PD) and compare the results with the healthy old and young control subjects. Furthermore, the aim was to define the optimal biceps brachii loading level that would most likely differentiate patients from controls. The results indicated that such nonlinear SEMG parameters as %Recurrence, %Determinism and SEMG distribution kurtosis, correlation dimension and sample entropy were significantly different between the PD patients and healthy controls. These novel nonlinear parameters, unlike traditional spectral or amplitude parameters, correlated with the Unified Parkinson's Disease Rating Scale (UPDRS) and finger tapping scores. The most significant between group differences were found in the loading condition where no additional weights were applied in isometric elbow flexion. No major difference of SEMG characteristics was detected between old and young control subjects. In conclusion, the novel SEMG parameters can differentiate the patients with PD from healthy control subjects and these parameters may have potential in the assessment of the severity of PD.
Meigal
A I
AI
Petrozavodsk State University, 185910 Petrozavodsk, Russian Federation.
Rissanen
S
S
Tarvainen
M P
MP
Karjalainen
P A
PA
Iudina-Vassel
I A
IA
Airaksinen
O
O
Kankaanpää
M
M
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001132:Arm / Q000503:physiopathology; D004576:Electromyography / Q000379:methods*; D005260:Female; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology*; D012016:Reference Values; D016474:Weight-Bearing