Alternative anticoagulation with danaparoid in two pregnancies in a patient with former heparin-induced thrombocytopenia (HIT), homozygous factor V Leiden mutation, a history of venous thrombosis and recurrent pregnancy losses.
Schindewolf
Marc
M
Division of Vascular Medicine, III. Medical Clinic, Department of Internal Medicine, Johann Wolfgang Goethe-University Hospital, Frankfurt/Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Marc.Schindewolf@kgu.de
Lindhoff-Last
Edelgard
E
D000026:Abortion, Habitual / Q000188:drug therapy; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D002809:Chondroitin Sulfates / Q000627:therapeutic use*; D003871:Dermatan Sulfate / Q000627:therapeutic use*; D005165:Factor V / Q000235:genetics*; D005166:Factor V Deficiency / Q000097:blood / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D006493:Heparin / Q000009:adverse effects; D006497:Heparan Sulfate / Q000627:therapeutic use*; D006720:Homozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010976:Platelet Count; D017354:Point Mutation; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000188:drug therapy* / Q000235:genetics*; D013921:Thrombocytopenia / Q000139:chemically induced; D014178:Translocation, Genetic; D020246:Venous Thrombosis / Q000150:complications
D000925:Anticoagulants; D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D005165:Factor V; D006493:Heparin; D006497:Heparan Sulfate; C095381:factor V Leiden; C035838:danaparoid