title: [Guidelines for the management of Helicobacter pylori--Maastricht III-2005 and Japanese guidelines].
abstract: The guidelines on the management of Helicobacter pylori were updated at the European Helicobacter study group third Maastricht consensus conference in March 2005. Especially, this conference emphasis on the management of non ulcer dyspepsia, GERD, and the patients who use non steroidal anti-inflammatory drug. Eradication of H. pylori is recommended in patients with peptic ulcer, low grade MALT lymphoma, atrophic gastritis, unexplained iron deficiency anemia, chronic idiopathic thrombocytopenic purpura and first degree relatives of patients with gastric cancer. H. pylori eradication is less effective than proton pomp inhibitor(PPI) treatment in preventing ulcer recurrence in long term NSAIDs users. This meeting also emphasized on the relationship between H. pylori and gastric cancer. The guideline concluded that H. pylori eradication has the potential to reduce the risk of gastric cancer development. Japanese guideline in 2003 does not mention the effect of eradication for prevention of gastric cancer. The H. pylori eradication and new strategy should be desirable for global strategy of gastric cancer prevention.
authors.affiliation: Department of Gastroenterology, Faculty of Medicine, Oita University.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kodama
authors.forename: Kazunari
authors.initials: K
authors.lastname: Murakami
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Okimoto
authors.forename: Toshio
authors.initials: T
authors.lastname: Fujioka
mesh_terms: D000658:Amoxicillin / Q000008:administration & dosage; D017291:Clarithromycin / Q000008:administration & dosage; D003245:Consensus Statements as Topic; D004359:Drug Therapy, Combination; D005060:Europe; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D007564:Japan; D017410:Practice Guidelines as Topic; D054328:Proton Pump Inhibitors / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000209:etiology / Q000517:prevention & control
chemical_list: D054328:Proton Pump Inhibitors; D000658:Amoxicillin; D017291:Clarithromycin