Rational design and gas-phase characterization of molecular capsules by self-assembly of a symmetric hexasubstituted benzene with seven-membered lactams.
A novel very simple C3-symmetric lactam has been rationally designed to self-assemble as dimers or larger platonic solid capsules. Its core flat benzene ring bears three seven-membered lactams, resulting in tripod molecules that aggregate into robust tetrameric capsules. The self-assembly process was templated by tetraethylammonium cations and proven to be reversible by ESI spectroscopy in various solvents.
Baillargeon
Pierre
P
Laboratoire de Synthèse Supramoléculaire, Département de Chimie, Institut de Pharmacologie, Université de Sherbrooke, 3001, 12e avenue nord, Sherbrooke Québec J1H 5N4, Canada.
Dory
Yves L
YL