[Influence of birth weight on the lipid profile and blood pressure in Madrid adolescents].
OBJECTIVE
The aim of this study is to assess the relationship between birth weight and the lipid profile and blood pressure in adolescents.


METHODS
Cross sectional study. We studied seven hundred and forty adolescents aged 18 who attended four different schools located in Madrid. Birth weight (BW) data were obtained from delivery records. All subjects underwent a physical examination, including measurement of blood pressure. Plasma lipids were determined using standardised methods after ten hour fasting.


RESULTS
Total cholesterol and cholesterol-LDL in males and females with BW < 3.000 grams were statistically greater than those from subjects with BW > 3,800 grams. Male adolescents also showed a difference in the apolipoprotein B (ApoB) levels. We only found a statistically significant difference in the diastolic blood pressure of male adolescents belonging to the extreme birth weight quintiles.


CONCLUSIONS
We found an inverse relationship between birth weight and total cholesterol and cholesterol LDL levels in males and females. This association was also noted in Apo B concentrations in male adolescents. The only influence birth weight had on blood pressure was on the diastolic blood pressure of males.
Arias Alvarez
M A
MA
Centro de Salud Santa Hortensia. Hospital Niño Jesús. Madrid. España. mariaariasalvarez@yahoo.es
Sánchez Bayle
M
M
D000293:Adolescent; D001724:Birth Weight; D002391:Catchment Area, Health; D002784:Cholesterol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006949:Hyperlipidemias / Q000175:diagnosis / Q000453:epidemiology*; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology*; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence; D013030:Spain / Q000453:epidemiology
D002784:Cholesterol