title: Recombinant factor VIIa for intraoperative bleeding in a child with hepatoblastoma and review of recombinant activated factor VIIa use in children undergoing surgery.
abstract: We report a case of a child with a large liver mass who underwent an open liver biopsy and had massive bleeding intraoperatively. Recombinant activated factor VII (rFVIIa) given intraoperatively was successful in stopping the bleeding. We also reviewed the literature on the use of rFVIIa in pediatric surgery.
authors.affiliation: Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada T3B 6A8. khoula.al-said@calgaryhealthregion.ca
authors.forename: Khoula
authors.initials: K
authors.lastname: Al-Said
authors.forename: Ronald
authors.initials: R
authors.lastname: Anderson
authors.forename: Andrew
authors.initials: A
authors.lastname: Wong
authors.forename: Doan
authors.initials: D
authors.lastname: Le
mesh_terms: D001706:Biopsy / Q000009:adverse effects; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002675:Child, Preschool; D017707:Erythrocyte Transfusion; D015942:Factor VIIa / Q000627:therapeutic use*; D018197:Hepatoblastoma / Q000601:surgery*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa