title: Supramolecular self-assembled arrangements of maltose glyconanoparticles.
abstract: Our group previously reported the preparation of water-soluble Au-Fe(x)O(y) nanoparticles functionalized with a maltose neoglycoconjugate. A fraction soluble in methanol was also separated and originated a new supramolecular polymeric aggregate. We report here the full characterization of this novel material by transmission electron microscopy (TEM), fluorescence emission, and atomic force microscopy. By means of noncontact dynamic atomic force microscopy, we have been able to obtain information about the organization of the organic components of the polymers, which eluded TEM analysis. We have observed that polymers packed in units about 65 nm in length and 40 nm in width on Au surfaces. The nanoparticles seem to be encapsulated by the organic material. We propose interactions between the sugar residues and the amphiphilic character of the maltose neoglycoconjugate (with a lipophilic undecane spacer) as responsible for the origin of these amazing supramolecular arrangements.
authors.affiliation: Instituto de Microelectrónica de Madrid (CSIC), E-28760 Tres Cantos, and Laboratory of Glyconanotechnology, CIC biomaGUNE-CIBER-BBN, E-20009 San SebastiAn, Spain.
authors.forename: Martina
authors.initials: M
authors.lastname: Fuss
authors.forename: Mónica
authors.initials: M
authors.lastname: Luna
authors.forename: David
authors.initials: D
authors.lastname: Alcantara
authors.forename: Jesús M de la
authors.initials: JM
authors.lastname: Fuente
authors.forename: Soledad
authors.initials: S
authors.lastname: Penadés
authors.forename: Fernando
authors.initials: F
authors.lastname: Briones
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry; D008320:Maltose / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D011108:Polymers / Q000737:chemistry
chemical_list: D005290:Ferric Compounds; D011108:Polymers; C000499:ferric oxide; D008320:Maltose