Transcranial Doppler blood flow assessment in patients with mild heart failure: correlates with neuroimaging and cognitive performance.
Cardiac output and cerebral perfusion are reduced in patients with advanced stages of heart failure. Our aim was to determine whether cerebral blood flow velocity measured by transcranial Doppler ultrasonography was reduced in outpatients with mild heart failure in comparison to controls and, if so, whether this reduction was related to cognitive performance and abnormalities of the brain diagnosed by magnetic resonance imaging.
Vogels
Raymond L C
RL
Department of Neurology, Sint Lucas-Andreas Hospital and the Department of Clinical Neuropsychology, VU University, Amsterdam, the Netherlands. r.vogels@vumc.nl
Oosterman
Joukje M
JM
Laman
David M
DM
Gouw
Alida A
AA
Schroeder-Tanka
Jutta M
JM
Scheltens
Philip
P
van der Flier
Wiesje M
WM
Weinstein
Henry C
HC
D000368:Aged; D001921:Brain / Q000098:blood supply*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003071:Cognition; D003072:Cognition Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011594:Psychometrics; D012039:Regional Blood Flow; D017585:Ultrasonography, Doppler, Transcranial