title: Assessing the proposed association between tooth agenesis and taurodontism in 975 paediatric subjects.
abstract: BACKGROUND
  An association between tooth agenesis and taurodontism has been suggested. The identification of subpopulations with specific associated dental anomalies (subphenotype) would allow testing of the specific hypothesis that certain genetic factors contribute to the specific subphenotype.
  
  
  OBJECTIVE
  This work aims to assess a large cohort to verify if the association between tooth agenesis and taurodontism is present.
  
  
  METHODS
  Panoramic radiographs of 1002 patients were examined and 975 were used in this study. The presence of tooth agenesis and taurodontism was assessed in the study population.
  
  
  RESULTS
  The frequency of tooth agenesis was 4.6% and the frequency of taurodontism was 1.6%. There were, however, no observations of concomitant tooth agenesis and taurodontism.
  
  
  CONCLUSIONS
  Our data do not support the hypothesis that isolated tooth agenesis is associated with isolated taurodontism.
authors.affiliation: Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Erika
authors.initials: E
authors.lastname: Calvano Küchler
authors.forename: Patrícia
authors.initials: P
authors.lastname: De Andrade Risso
authors.forename: Marcelo
authors.initials: M
authors.lastname: De Castro Costa
authors.forename: Adriana
authors.initials: A
authors.lastname: Modesto
authors.forename: Alexandre Rezende
authors.initials: AR
authors.lastname: Vieira
mesh_terms: D000848:Anodontia / Q000000981:diagnostic imaging / Q000453:epidemiology*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D015331:Cohort Studies; D015897:Comorbidity; D003786:Dental Pulp Cavity / Q000002:abnormalities*; D005260:Female; D006801:Humans; D008297:Male; D011862:Radiography, Panoramic; D014071:Tooth Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*