title: Expression of three serine protease genes from the South East Asian malaria vector, Anopheles dirus, in relation to blood feeding and parasite infection.
abstract: Three serine protease cDNA clones were isolated from Anopheles dirus, a major vector of malaria in Southeast Asia. Transcript abundance was examined following infection by Plasmodium falciparum by RT-PCR analysis. SerF3 exhibited increased transcript abundance in the whole body at 10 days post-infection with P. falciparum. All three genes are candidates for further investigation to determine their roles in mosquito immune responses.
authors.affiliation: Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
authors.forename: Patchara
authors.initials: P
authors.lastname: Sriwichai
authors.forename: Yupha
authors.initials: Y
authors.lastname: Rongsriyam
authors.forename: Narissara
authors.initials: N
authors.lastname: Jariyapan
authors.forename: Chamnarn
authors.initials: C
authors.lastname: Apiwathnasorn
authors.forename: Jetsumon
authors.initials: J
authors.lastname: Sattabongkot
authors.forename: Susan
authors.initials: S
authors.lastname: Paskewitz
mesh_terms: D000818:Animals; D000852:Anopheles / Q000201:enzymology / Q000235:genetics* / Q000469:parasitology*; D001483:Base Sequence; D001769:Blood; D005247:Feeding Behavior; D015870:Gene Expression; D017344:Genes, Insect; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000502:physiology*; D012697:Serine Endopeptidases / Q000235:genetics*
chemical_list: D012697:Serine Endopeptidases