title: Aspergillus fumigatus endocarditis in a pediatric liver transplant recipient: favorable outcome without cardiac surgery.
abstract: Transplant recipients are very susceptible to invasive aspergillosis, which increases mortality rate. Disseminated aspergillosis in the liver transplant recipient can affect virtually any organ and endocarditis is often lethal despite cardiac surgery and antifungal therapy. We report the case of a eight-month-old girl who presented with Aspergillus fumigatus endocarditis 18 days after liver transplantation that was successfully treated by a combination of antifungal drugs associated to a low dosage of immunosuppressive therapy.
authors.affiliation: Hepatology and National Reference Centre for Biliary Atresia, Bicêtre Hospital University of Paris, France.
authors.forename: Olivia
authors.initials: O
authors.lastname: Mourier
authors.forename: Philippe
authors.initials: P
authors.lastname: Durand
authors.forename: Virginie
authors.initials: V
authors.lastname: Lambert
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bretagne
authors.forename: Chantal
authors.initials: C
authors.lastname: Maurage
authors.forename: Sophie
authors.initials: S
authors.lastname: Branchereau
authors.forename: Olivier
authors.initials: O
authors.lastname: Bernard
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Jacquemin
mesh_terms: D000284:Administration, Oral; D001228:Aspergillosis / Q000209:etiology* / Q000382:microbiology; D001232:Aspergillus fumigatus / Q000378:metabolism*; D015150:Echocardiography, Doppler / Q000379:methods; D004696:Endocarditis / Q000209:etiology* / Q000382:microbiology*; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents