title: [Biological monitoring in workers exposed to inorganic arsenic in a disused industrial plant in the area of Manfredonia].
abstract: Inorganic arsenic and its methylated metabolities were measured in 108 spot urine samples obtained from the medical surveillance programme of workers exposed to inorganic Arsenic in July 2006. 15% of the samples showed levels higher than limit value of 35 microg/L (mean value 23,9 microg/L). After the improvement of the working conditions, in August-October 2006, we collected a urinary sample from each of the 108 workers enrolled. A questionnaire was also administrated, in order to investigate the influence of occupational and non occupational factors on the urinary arsenic excretion. The median value of urinary arsenic was 15,12 microg/L; among the 108 samples, 5% showed levels higher than limit value. A significant difference was observed in relation with sea-food consumption and aging stratification. In conclusion, we have described a significant reduction of urinary arsenic excretion between the two phases of biological monitoring, likely due to a proper hygienic work-related intervention.
authors.affiliation: Dipartimento di Medicina Interna e Medicina Pubblica, Sezione di Medicina del Lavoro B. Ramazzini, Facoltà di Medicina e Chirurgia, Università degli Studi di Bari, Policlinico, Piazza G. Cesare 11, 70124 Bari. l.vimercati@medlav.uniba.it
authors.forename: L
authors.initials: L
authors.lastname: Vimercati
authors.forename: A
authors.initials: A
authors.lastname: Carrus
authors.forename: T
authors.initials: T
authors.lastname: Gagliardi
authors.forename: G
authors.initials: G
authors.lastname: Sciannamblo
authors.forename: F
authors.initials: F
authors.lastname: Caputo
authors.forename: V
authors.initials: V
authors.lastname: Minunni
authors.forename: M R
authors.initials: MR
authors.lastname: Bellotta
authors.forename: G
authors.initials: G
authors.lastname: de Nichilo
authors.forename: L
authors.initials: L
authors.lastname: Bisceglia
authors.forename: V
authors.initials: V
authors.lastname: Corrado
authors.forename: P
authors.initials: P
authors.lastname: De Pasquale
authors.forename: G
authors.initials: G
authors.lastname: Assennato
mesh_terms: D001151:Arsenic / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D004784:Environmental Monitoring; D006801:Humans; D007221:Industry; D007558:Italy; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016272:Occupational Health; D011159:Population Surveillance
chemical_list: D015415:Biomarkers; D001151:Arsenic