title: [Experience with using of solutions of hydroxyethyl starch (refortan and voluven) in neuroanesthesiology].
abstract: The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exerts a more pronounced effect on the indices of hemodynamics as compared with voluven, but its modifying action on the hemostasis system is also more pronounced. These medicines used in doses 6-8 ml/kg fail to have substantial effects on efficiency of hemostasis in the brain wound and do not increase risk of postoperative hemorrhagic complications.
authors.forename: A N
authors.initials: AN
authors.lastname: Kondrat'ev
authors.forename: I A
authors.initials: IA
authors.lastname: Savvina
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Novikov
authors.forename: N V
authors.initials: NV
authors.lastname: Driagina
mesh_terms: D000758:Anesthesia / Q000379:methods*; D006439:Hemodynamics / Q000187:drug effects*; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D007430:Intraoperative Care / Q000379:methods; D008875:Middle Aged; D009422:Nervous System Diseases / Q000503:physiopathology / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods*; D010642:Phenoxyacetates / Q000008:administration & dosage*; D010952:Plasma Substitutes / Q000008:administration & dosage*
chemical_list: C485123:HES 130-0.4; D006895:Hydroxyethyl Starch Derivatives; D010642:Phenoxyacetates; D010952:Plasma Substitutes; C022160:refortan