title: [Systemic BCG reactions after intravesical BCG therapy. A report of four cases].
abstract: Local Bacillus Calmette-Guerin (BCG) immunotherapy is an effective and widely used treatment for superficial bladder carcinoma. Local side effects are frequent, whereas systemic side effects are rare, but more serious. We report four cases of systemic BCG reaction. Although uncommon, this infectious complication of BCG therapy should always be considered in the appropriate clinical setting. The best approach to minimize this complication is a strict compliance with precautions and a close and rigorous surveillance of this drug.
authors.affiliation: Service d'Urologie, Hôpital Charles Nicolle, Tunis, Tunisie. momosfa@yahoo.fr
authors.forename: Mohamed
authors.initials: M
authors.lastname: Sfaxi
authors.forename: Houda
authors.initials: H
authors.lastname: Langar
authors.forename: Akrem
authors.initials: A
authors.lastname: Ouni
authors.forename: Yosra
authors.initials: Y
authors.lastname: Riahi
authors.forename: Sihem
authors.initials: S
authors.lastname: El Aidli
authors.forename: Riadh
authors.initials: R
authors.lastname: Daghfous
authors.forename: Abdeladhim
authors.initials: A
authors.lastname: Ben Abdeladhim
authors.forename: Mohamed
authors.initials: M
authors.lastname: Chébil
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects* / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine