title: Preterm birth, ovarian endometriomata, and assisted reproduction technologies.
abstract: OBJECTIVE
  To report preterm birth and small for gestational age (SGA) rates from assisted reproduction technologies (ART) patients with ovarian endometriomata compared with control groups.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Tertiary university affiliated ART center and Perinatal Data Collection Unit (PDCU).
  
  
  METHODS
  Every woman who had an ART singleton baby born between 1991 and 2004 had her database record assessed (N = 4382). Control groups included 1201 singleton babies from ART patients without endometriosis and 2400 randomly selected women from the PDCU database of 850,000 births.
  
  
  METHODS
  There were 95 singleton ART babies from patients with ovarian endometriomata and 535 ART singleton babies from patients who had endometriosis but no ovarian endometriomata.
  
  
  METHODS
  Preterm birth rates and SGA birth rates.
  
  
  RESULTS
  Preterm birth rate increased only in the ovarian endometriomata group when compared with community birth records (n = 850,000). Furthermore, ART patients with ovarian endometriomata had a statistically significantly increased likelihood of having a SGA baby when compared with other forms of endometriosis.
  
  
  CONCLUSIONS
  Rates of preterm birth and SGA babies doubled in infertility patients with ovarian endometriomata who required ART.
authors.affiliation: Department of Obstetrics and Gynecology, Monash University, Clayton, Victoria, Australia.
authors.forename: Shavi
authors.initials: S
authors.lastname: Fernando
authors.forename: Sue
authors.initials: S
authors.lastname: Breheny
authors.forename: Alice M
authors.initials: AM
authors.lastname: Jaques
authors.forename: Jane L
authors.initials: JL
authors.lastname: Halliday
authors.forename: Gordon
authors.initials: G
authors.lastname: Baker
authors.forename: David
authors.initials: D
authors.lastname: Healy
mesh_terms: D000328:Adult; D001723:Birth Rate; D016022:Case-Control Studies; D004715:Endometriosis / Q000150:complications* / Q000628:therapy; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D016017:Odds Ratio; D010049:Ovarian Diseases / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D047928:Premature Birth / Q000209:etiology*; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors