title: [Expressions of interleukin 4 mRNA and interferonjgamma mRNA of condyloma acuminata].
abstract: OBJECTIVE
  To study the expressions of interleukin 4 (IL-4) mRNA and interferon-gamma (IFN-gamma) mRNA of condyloma acuminata in order to obtain a clue as to the immunological mechanisms possibly relevant for warts regression or persistence.
  
  
  METHODS
  In situ RT-PCR was employed in surgically removed warts of 22 recurrent patients, 14 non-recurrent patients and 15 normal controls, respectively.
  
  
  RESULTS
  The expression of IFN-gamma mRNA in the non-recurrent warts was higher than in recurrent warts (P<0.01); but the expression of IL-4 mRNA in the recurrent warts was higher than in non-recurrent warts (P<0.01).
  
  
  CONCLUSIONS
  A higher IFN-gamma mRNA expression of condyloma acuminata lesions might contribute to warts regression.
authors.affiliation: Department of Dermatology, NO.3 People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 201900, China. mayong@126.com
authors.forename: Yong
authors.initials: Y
authors.lastname: Ma
authors.forename: Tong
authors.initials: T
authors.lastname: Liu
mesh_terms: D000328:Adult; D003218:Condylomata Acuminata / Q000235:genetics*; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000235:genetics*; D015847:Interleukin-4 / Q000235:genetics*; D008297:Male; D012333:RNA, Messenger / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D055815:Young Adult
chemical_list: D012333:RNA, Messenger; D015847:Interleukin-4; D007371:Interferon-gamma