[Application of BED-CEIA to estimate the human immunodeficiency virus prevalence among injecting drug users in Chongqing municipality].
OBJECTIVE
To estimate the human immunodeficiency virus (HIV-1) prevalence of injecting drug users (IDUs) in Chongqing city.


METHODS
To apply BED-capture enzyme immunoassay (CEIA) which was based on the principle of HIV-antibody varies as the disease progress, in order to estimate both the HIV incidence and prevalence of IDUs from two IDUs surveillance sites in Chongqing.


RESULTS
During the research period, 4711 serum samples were tested by ELISA and 130 were HIV-1 positive, confirmed by Western blot. The prevalence of IDUs surveillance site A from 1999 to 2006 were 0.73%, 2.02%, 1.54%, 2.96% and 2.80%, and the incidence rates were 0.57%, 0.93%, 0,1.24% and 1.68% respectively. The prevalence of IDUs surveillance site B appeared to be 4.21%, 9.96%, 8.13%, and the incidence rates were 0.95%, 1.04% and 0.90% respectively, from 2004 to 2006.


CONCLUSIONS
Many of the IDUs HIV carriers in Chongqing had been infected for long time, and the incidence rates among them were steady, keeping at the same level for 1-2 years. Promotion on intervention for IDUs had produced certain effects but more attention still needs to be paid.
Han
Mei
M
Chongqing Center for Disease Control and Prevention, Chongqing 400042, China.
Wang
Yu-lin
YL
Wang
Min-jie
MJ
Zhou
Quan-hua
QH
Jiang
Yan
Y
D015492:AIDS Serodiagnosis / Q000379:methods*; D002681:China / Q000453:epidemiology; D055030:Drug Users; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology*; D015528:HIV Seroprevalence; D006801:Humans; D007124:Immunoenzyme Techniques; D015994:Incidence; D011159:Population Surveillance; D015995:Prevalence; D015819:Substance Abuse, Intravenous / Q000453:epidemiology / Q000821:virology*; D014505:Urban Population / Q000706:statistics & numerical data
D015483:HIV Antibodies