title: Fluorescein angiography of iris juvenile xanthogranuloma.
abstract: A 3-year-old boy was referred because of the presence of a non-pigmented, highly vascular mass with tapioca appearance involving the superior portion of the left iris. Iris fluorescein angiography revealed early hyperfluorescence of the iris tumor with diffuse, intense late leakage of dye throughout the entire iris, not just in the region of the tumor. Cytopathologic examination revealed Touton giant cells and the presence of histiocytes, confirming the diagnosis of iris juvenile xanthogranuloma. The patient was prescribed topical prednisolone acetate, and the lesion resolved during the next 3 months. Fluorescein angiography may be useful in differentiating iris juvenile xanthogranuloma from malignant or non-inflammatory benign iris lesions.
authors.affiliation: Oncology Service, Suite 1440, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA.
authors.forename: Carl J
authors.initials: CJ
authors.lastname: Danzig
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Arman
authors.initials: A
authors.lastname: Mashayekhi
authors.forename: Hormoz
authors.initials: H
authors.lastname: Ehya
authors.forename: Maria E
authors.initials: ME
authors.lastname: Manquez
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007498:Iris / Q000098:blood supply; D007499:Iris Diseases / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone