title: Soraphinol C, a new free-radical scavenger from Sorangium cellulosum.
abstract: A new compound named soraphinol C (1) was isolated from myxobacteria Sorangium cellulosum KM1001 a soil isolate, together with a structurally related known compound, 4-hydroxysattabacin (2). These compounds were isolated by silica gel column chromatography and recycling preparative HPLC, consecutively. The structures of the compounds were determined on the basis of combined spectroscopic analyses. Compounds 1 and 2 exhibited antioxidant activity as a radical scavenger in the experiment using a hydrophilic free-radical initiator, 2,2'-azobis(2-amidinopropane)dihydrochloride with ORAC values of 0.956 and 0.617, respectively.
authors.affiliation: College of Pharmacy, Sungkyunkwan University, Suwon 440-746, Korea.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Li
authors.forename: Tae-Kyung
authors.initials: TK
authors.lastname: Yu
authors.forename: Jong Hwan
authors.initials: JH
authors.lastname: Kwak
authors.forename: Byoung-Yil
authors.initials: BY
authors.lastname: Son
authors.forename: Youngwan
authors.initials: Y
authors.lastname: Seo
authors.forename: Ok-Pyo
authors.initials: OP
authors.lastname: Zee
authors.forename: Jong-Woong
authors.initials: JW
authors.lastname: Ahn
mesh_terms: D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006588:Hexanones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009231:Myxococcales / Q000378:metabolism*; D012988:Soil Microbiology
chemical_list: D016166:Free Radical Scavengers; D006588:Hexanones; C529903:soraphinol C; C096625:hydroxysattabacin