title: A patient with diffuse large B-cell non-Hodgkin's lymphoma and AA type amyloidosis.
abstract: AA-type amyloidosis is a consequence of a long-standing systemic inflammation and is not associated with a monoclonal protein or clonal bone marrow plasma cells. Proinflammatory cytokines such as interleukin (IL)1, IL-6, and tumor necrosis factor (TNF) stimulate the synthesis of serum amyloid A during inflammation. Although the association of non-Hodgkin's lymphoma (NHL) with AL-type amyloidosis is well known and patients with Hodgkin's lymphoma with AA amyloidosis have been described, AA-type amyloidosis with NHL is extremely infrequent. We report a case of amyloidosis associated with NHL that subsided during R-CHOP chemotherapy.
authors.affiliation: Department of Hematology, Dokuz Eylul University, School of Medicine, Izmir, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Piskin
authors.forename: I
authors.initials: I
authors.lastname: Alacacioglu
authors.forename: S
authors.initials: S
authors.lastname: Ozkal
authors.forename: M A
authors.initials: MA
authors.lastname: Ozcan
authors.forename: F
authors.initials: F
authors.lastname: Demirkan
authors.forename: G
authors.initials: G
authors.lastname: Hayri Ozsan
authors.forename: A
authors.initials: A
authors.lastname: Kargi
authors.forename: B
authors.initials: B
authors.lastname: Undar
mesh_terms: D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D000685:Serum Amyloid A Protein / Q000378:metabolism*
chemical_list: D000685:Serum Amyloid A Protein