Modifications of interdental papilla microcirculation: a possible cause of periodontal disease in Hashimoto's thyroiditis?
BACKGROUND
Hypothyroidism is defined by a decrease in thyroid hormone production and thyroid gland function. The aim of the present research has been to evaluate the morphologic interdental papilla microcirculation of patients suffering from Hashimoto thyroiditis (HT) and to evaluate a possible correlation with the associated periodontal disease.


METHODS
Fifteen healthy subjects and 15 patients suffering from HT were examined. The patients who showed conditions known to compromise microcirculation, such as diabetes, hypertension and pharmacological treatments, were not included in the group of healthy patients. All patients were non-smokers. Gingival capillaroscopy was used to investigate the characteristics of microcirculation. Visibility, course, tortuosity, the average caliber of the capillary loops and the number of visible capillary loops per square millimeter were evaluated for each patient.


RESULTS
An interdental papilla vascular modification results in HT. In patients suffering from HT, it was possible to observe a reduced caliber of capillaries, as well as a greater number and tortuosity of capillary loops.


CONCLUSIONS
This study shows that capillary alterations in patients suffering from HT occur in gingival microcirculation.
Scardina
Giuseppe Alessandro
GA
Department of Oral Sciences G. Messina, University of Palermo, Dr. Scardina Giuseppe Alessandro via Del Vespro, 129-90127 Palermo, Italy. scardina@odonto.unipa.it
Messina
Pietro
P
D000328:Adult; D002196:Capillaries / Q000166:cytology / Q000473:pathology; D003771:Dental Papilla / Q000098:blood supply / Q000166:cytology / Q000473:pathology*; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000166:cytology / Q000473:pathology; D010510:Periodontal Diseases / Q000209:etiology / Q000473:pathology*; D012016:Reference Values