Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family.
Seven receptors with highly homologous structural features have recently been discovered that belong to a new family of seven membrane-spanning receptors within the G-protein-linked receptor superfamily. These seven all bind small peptide ligands, and many have the unique property to activate the G(S) and at least one other G protein.
Segre
G V
GV
Endocrine Unit, Massachusetts General Hospital, USA; Department of Medicine, Harvard Medical School, USA; New England Deaconess Hospital, Boston, MA 02114, USA.
Goldring
S R
SR