Gas-phase stereoselective binding to Mn/salen catalysts.
Gas-phase equilibrium measurements have been used to determine the stereoselectivity of binding the enantiomers of 1-phenylethanol to manganese/salen asymmetric epoxidation catalysts. There is significant selectivity in the gas-phase binding, and the results are compared to data from condensed-phase epoxidations. The study demonstrates the utility of a novel internal standard approach that allows for rapid, accurate measures of the stereoselectivity of gas-phase ligand binding. Moreover, the data suggest that gas-phase binding stereoselectivity could be a potential predictor of condensed-phase enantioselectivity.
Fagin
Adelaide E
AE
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Wang
Guoping
G
Lau
Michel C
MC
Gronert
Scott
S