[Reparative regeneration of calvarial bones].
The patterns of reparative osteohistogenesis were studied using the model of defects of rabbit parietal bones (n=18) with light and scanning electron microscopy and morphometry. Posttraumatic regeneration of cranial calvarial bones was shown to include main stages, which were also characteristic for long tubular bones, such as: primary response to trauma, reparative osteohistogenesis and adaptive remodeling. In every stage, temporary cellular associations are functioning within the regenerate. These are regeneratory histions which are cellular effectors of reparative process based on the regularities of physiologic osteogenesis including the phases of resorption, reversion, formation and rest. By day 120 the injured area was shown to be filled predominantly with dense connective tissue, which is associated with functional adaptation without the action of physical load.
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D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D010012:Osteogenesis; D011817:Rabbits; D012886:Skull / Q000502:physiology* / Q000648:ultrastructure