A highly efficient and selective synthesis of 1,2,3-triazole linked saccharide nucleosides via "click chemistry".
A series of 1,2,3-triazole linked saccharide nucleosides were synthesized in high yield and selectivity via "click chemistry" of the 3'-azido-2'-deoxythymidine and the propargyl carbohydrates. [image omitted].
Ding
Haixin
H
Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Jiangxi, PR China.
Yang
Ruchun
R
Song
Yang
Y
Xiao
Qiang
Q
Wu
Jun
J
D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D009844:Oligosaccharides / Q000737:chemistry*; D013379:Substrate Specificity; D014230:Triazoles / Q000737:chemistry*
D000998:Antiviral Agents; D009705:Nucleosides; D009844:Oligosaccharides; D014230:Triazoles