title: Poised polymerases: on your mark...get set...go!
abstract: Recent global analyses have determined that many Drosophila and human genes have engaged polymerase molecules trapped immediately downstream of promoters. These results strongly implicate RNA polymerase II elongation control as a major regulator of differentiation and development.
authors.affiliation: Biochemistry Department, University of Iowa, Iowa City, IA 52240, USA. david-price@uiowa.edu
authors.forename: David H
authors.initials: DH
authors.lastname: Price
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D042925:Positive Transcriptional Elongation Factor B / Q000378:metabolism; D011401:Promoter Regions, Genetic; D014176:Protein Biosynthesis; D012319:RNA Polymerase II / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D042925:Positive Transcriptional Elongation Factor B; D012319:RNA Polymerase II