Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing.
A simple strategy for pattern recognition of proteins through micellar disassembly is introduced. Five different noncovalently assembled receptors have been generated, and the disassembly was studied by monitoring the encapsulated dye release in response to five different proteins. The disassembly induced fluorescence change of the guest molecule produces protein-specific patterns.
Savariar
Elamprakash N
EN
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Ghosh
Suhrit
S
González
Daniella C
DC
Thayumanavan
S
S
D000180:Acrylic Resins / Q000737:chemistry*; D001665:Binding Sites; D002593:Cetrimonium Compounds / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*; D001617:beta-Glucosidase / Q000737:chemistry*
D000180:Acrylic Resins; D002593:Cetrimonium Compounds; D004573:Electrolytes; D013501:Surface-Active Agents; D001617:beta-Glucosidase