[Localization of bcl-2 antiapoptotic protein in the human placenta].
The aim of this investigation was to study the distribution of bcl-2 antiapoptotic protein in various structures of human placenta using immunocytochemical methods. Syncytiotrophoblast was found to have the greatest bcl-2 immunoreactivity, while cytotrophoblastic elements, connective tissue cells of the villi and the blood vessel walls were bcl-2-negative. It is suggested that accumulation of bcl-2 in the syncytiotrophoblast may reflect its high resistance to detrimental factors.
Korzhevskiĭ
D E
DE
Otellin
V A
VA
Starorusskaia
A N
AN
Pavlova
N G
NG
D017209:Apoptosis; D002824:Chorionic Villi / Q000378:metabolism; D005260:Female; D006801:Humans; D010920:Placenta / Q000033:anatomy & histology / Q000098:blood supply / Q000378:metabolism*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*; D014327:Trophoblasts / Q000166:cytology / Q000378:metabolism*
D019253:Proto-Oncogene Proteins c-bcl-2