title: Building better beta cells.
abstract: Type 1 diabetes represents an attractive target for human embryonic stem cell (hESC)-based cell replacement therapies. Recently, in Nature Biotechnology, Kroon et al. (2008) reported encouraging progress toward this goal with the development of functional islet-like structures in mice transplanted with hESC-derived pancreatic endoderm.
authors.affiliation: Monash Immunology and Stem Cell Laboratories, Level 3, Building 75, STRIP 1, West Ring Road, Monash University, Clayton, Victoria 3800, Australia. ed.stanley@med.monash.edu.au
authors.forename: Edouard G
authors.initials: EG
authors.lastname: Stanley
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Elefanty
mesh_terms: D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000378:metabolism / Q000637:transplantation; D006801:Humans; D050417:Insulin-Secreting Cells / Q000166:cytology* / Q000378:metabolism / Q000637:transplantation; D033581:Stem Cell Transplantation