title: Pathology of inverted Takotsubo cardiomyopathy.
abstract: Myocardial dysfunction without coronary involvement may occur in acute cerebral diseases. The inverted Takotsubo pattern has been recently recognized as a novel heart neurologic stress-related syndrome. We report on the case of a 40-year-old woman presenting with massive subarachnoid hemorrhage and brain death. Echocardiography revealed an extensive left ventricular circumferential akinesis except at the apex. Histologic analysis of the heart confirmed the absence of myocardial infarction and revealed only sparse foci of myocyte necrosis with contraction bands in the akinetic areas.
authors.affiliation: Echocardiography and Physiology Laboratories, Lille Medical University Center, Lille, France. sylvestre.marechaux@yahoo.fr
authors.forename: Sylvestre
authors.initials: S
authors.lastname: Maréchaux
authors.forename: Paul
authors.initials: P
authors.lastname: Fornes
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Petit
authors.forename: Catherine
authors.initials: C
authors.lastname: Poisson
authors.forename: Didier
authors.initials: D
authors.lastname: Thevenin
authors.forename: Thierry
authors.initials: T
authors.lastname: Le Tourneau
authors.forename: Philippe
authors.initials: P
authors.lastname: Asseman
authors.forename: Patrick
authors.initials: P
authors.lastname: Bruneval
authors.forename: Pierre-Vladimir
authors.initials: PV
authors.lastname: Ennezat
mesh_terms: D000328:Adult; D001926:Brain Death; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009206:Myocardium / Q000473:pathology; D009336:Necrosis / Q000473:pathology; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000473:pathology; D054549:Takotsubo Cardiomyopathy / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000473:pathology* / Q000503:physiopathology