title: [Metabolic syndrome and work: identification of populations at risk].
abstract: OBJECTIVE
  To assess whether shift work has a cause-effect nexus with the incidence of metabolic syndrome.
  
  
  METHODS
  Retrospective follow-up study, case-control type.
  
  
  METHODS
  A total of 202 female and male nurses, aged 23-60 years, having a 1 year minimal follow-up, and without any metabolic syndrome criterion at the first visit were evaluated. The ATP modified criteria were applied for the diagnosis of metabolic syndrome. Moreover smoking habitus, alcohol consumption, educational level and physical activity were considered as bias factors. The sample was divided in two groups doing or not night shifts.
  
  
  RESULTS
  The metabolic syndrome incidence resulted significantly greater in shift workers than in other workers (OR: 4.10, 95% CI 1.34-12.55, p = 0.01). The difference was more evident in subjects aged < 40 years (OR = 6.6, 95% CI 1.05-40.85, p = 0.04) the different metabolic syndrome incidence between two groups was detectable even after the multivariate analyse, which considered all the bias factors evaluated.
  
  
  CONCLUSIONS
  This study shows for the first time that the night shift work is associated with a greater risk to develop metabolic syndrome in workers healthy in baseline conditions.
authors.affiliation: Istituto medicina del Lavoro, Dipartimento di Medicina Interna, Università Cattolica del Sacro Cuore, Roma. monique_78@libero.it
authors.forename: M
authors.initials: M
authors.lastname: La Sala
authors.forename: A
authors.initials: A
authors.lastname: Pietroiusti
authors.forename: A
authors.initials: A
authors.lastname: Magrini
authors.forename: L
authors.initials: L
authors.lastname: De Santis
authors.forename: A
authors.initials: A
authors.lastname: Babbucci
authors.forename: A
authors.initials: A
authors.lastname: Bergamaschi
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D016272:Occupational Health; D012189:Retrospective Studies; D012307:Risk Factors; D014940:Work Schedule Tolerance