title: Biofilm production by clinical strains of Acinetobacter baumannii isolated from patients hospitalized in two tertiary care hospitals.
abstract: Microbial biofilms are considered as virulence factors. During the present study, 34 clinical strains of Acinetobacter baumannii, isolated from patients hospitalized in two tertiary care hospitals, were examined for biofilm formation. These strains showed high variability in biofilm formation. Furthermore, no relation could be found between the ability of biofilm production and molecular type, carbapenem resistance, site of isolation of the clinical strains of A. baumannii and disease severity. Interestingly, in two cases an increase in biofilm formation could be detected in A. baumannii isolates cultured from the same patient upon prolonged hospitalization.
authors.affiliation: Department of Medical Microbiology, Medical University of Warsaw, Poland. wroblewska@ib.amwaw.edu.pl
authors.forename: Marta M
authors.initials: MM
authors.lastname: Wroblewska
authors.forename: Anna
authors.initials: A
authors.lastname: Sawicka-Grzelak
authors.forename: Halina
authors.initials: H
authors.lastname: Marchel
authors.forename: Miroslaw
authors.initials: M
authors.lastname: Luczak
authors.forename: Alex
authors.initials: A
authors.lastname: Sivan
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D018441:Biofilms / Q000254:growth & development*; D015780:Carbapenems / Q000494:pharmacology; D003428:Cross Infection / Q000382:microbiology*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests; D019105:Random Amplified Polymorphic DNA Technique; D012189:Retrospective Studies
chemical_list: D015780:Carbapenems; D004269:DNA, Bacterial