title: Differentiation of ischemic and dilated cardiomyopathy on electrocardiograms.
abstract: Differentiating coronary artery disease with left ventricular dysfunction from dilated cardiomyopathy is important prognostically and therapeutically. To provide a diagnostic algorithm to distinguish these conditions using a standard 12-lead electrocardiogram, all 105 patients with left ventricular ejection fraction < 50% who underwent angiography between January 2004 and December 2006 were studied prospectively. Coronary artery disease was defined as >/= 50% stenosis of the left main coronary artery or >/= 70% stenosis of 1 or more of the 3 major epicardial arteries. Normal coronary angiography findings with left ventricular ejection fraction < 50% was defined as dilated cardiomyopathy. The most specific finding for differentiation of these diseases was pathologic Q waves in lead II, aVF, V3 or V4. The most sensitive parameter was a ratio >/= 5 of R-wave amplitudes in lead V6 and lead III (94% sensitive). The 12-lead electrocardiogram provides a useful noninvasive method for differentiation of dilated cardiomyopathy from coronary artery disease with left ventricular systolic dysfunction.
authors.affiliation: Department of Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Kamran
authors.initials: K
authors.lastname: Aghasadeghi
authors.forename: Amir
authors.initials: A
authors.lastname: Aslani
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D009202:Cardiomyopathies / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000503:physiopathology