title: Five-year prospective clinical evaluation of highly crystalline HA MP-1-coated dental implants.
abstract: Contemporary plasma-sprayed hydroxylapatite (HA) coatings with high crystalline content are much more resistant to in vivo degradation than HA coatings of a decade ago but reportedly exhibit reduced wettability, which could potentially negatively affect tissue adhesion and long-term clinical outcome. The present prospective study was undertaken to determine if highly crystalline HA MP-1-coated implants could meet a minimum 5-year implant success rate standard of 85% in view of their previously reported decreased wettability. Study subjects were consecutive patients with 1 or more missing teeth in the maxillary and/or mandibular jaw who presented in 3 university dental clinics and 1 private dental practice. A total of 120 patients were treated per protocol and successfully restored with implant-supported prostheses. Four implants failed in 3 patients and were withdrawn from the study. There were no other irresolvable adverse events. Cumulative implant success at 5 years was 97% (n = 184 implants in 88 patients), which exceeded the 85% standard for implant success after 5 years of clinical function.
authors.affiliation: University of Rochester Medical Center, Rochester, NY 14642, USA. Todd_Thierer@urmc.rochester.edu
authors.forename: Todd
authors.initials: T
authors.lastname: Thierer
authors.forename: John P
authors.initials: JP
authors.lastname: Davliakos
authors.forename: J Daulton
authors.initials: JD
authors.lastname: Keith
authors.forename: John J
authors.initials: JJ
authors.lastname: Sanders
authors.forename: Dennis P
authors.initials: DP
authors.lastname: Tarnow
authors.forename: James A
authors.initials: JA
authors.lastname: Rivers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020099:Coated Materials, Biocompatible; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D017886:Durapatite; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053758:Nanoparticles; D017060:Patient Satisfaction; D011446:Prospective Studies; D013499:Surface Properties; D017155:Wettability
chemical_list: D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D017886:Durapatite