[Relationship between RhoA/Rho-kinase signaling pathway and penile erection].
Erectile dysfunction (ED) has been plaguing men for a long time and the incidence of this disease is as high as 52% among males aged between 40 and 70. Recent discovery has shown a connection between the RhoA/Rho-kinase signaling system and ED. This paper reviews the progress in the study of RhoA/Rho-kinase signaling pathway, expounds its mechanism in penile erection and provides a base for further research on the role of RhoA/Rho-kinase signaling pathway in penile erection.
Zhu
Ping-Yu
PY
Department of Urology, the Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, China. zhupy1999_2004@sohu.com
Jiang
Rui
R
D000818:Animals; D006801:Humans; D008297:Male; D010410:Penile Erection / Q000502:physiology*; D011817:Rabbits; D015398:Signal Transduction / Q000502:physiology*; D054460:rho-Associated Kinases / Q000378:metabolism*; D020742:rhoA GTP-Binding Protein / Q000378:metabolism*
D054460:rho-Associated Kinases; D020742:rhoA GTP-Binding Protein