title: [Virus C hepatitis: successful therapy in a health care worker].
abstract: Hepatitis C viral is a problem of population health. The World Health Organization considers Hepatitis C an epidemic, a "silent" epidemic because a patient living with Hepatitis C can be infected for decades before being discovered. Recent data show an estimated number of 170 million patients infected with hepatitis C virus in the world. Number of new infections per year has declined from an average of 240,000 in the 1980s to about 26,000 in 2004. The incidence of HCV infected patients is estimated to 500-600 new cases in a year in Italy. Chronic infection is present in 55%-85% of infected persons. Approximately one third of the patients develop cirrhosis over a number of years, which can lead to liver failure and other serious complications. There is no vaccine and no completely effective treatment. Recent data show PEG-IFN-RBV combination therapy is most effective. We describe one HCV infected individual case report with HCV genotype 1b who received combination therapy for 4 weeks. Levels of HCV RNA became undetectable after an mouth of treatment.
authors.affiliation: Azienda Regionale Emergenza Sanitaria del Lazio ARES 118.
authors.forename: S
authors.initials: S
authors.lastname: Fantini
authors.forename: L
authors.initials: L
authors.lastname: Zarelli
authors.forename: P
authors.initials: P
authors.lastname: Tomao
authors.forename: N
authors.initials: N
authors.lastname: Vonesch
authors.forename: S
authors.initials: S
authors.lastname: Signorini
authors.forename: A
authors.initials: A
authors.lastname: Martini
mesh_terms: D006282:Health Personnel; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction