title: Estrogenic soybean isoflavones and chronic disease Risks and benefits.
abstract: Many edible plants contain natural estrogens called phytoestrogens. These compounds possess mixed estrogen agonist-antagonist properties that are organ-specific in vivo. We have focused on estrogenic soybean isoflavones because of their potential extensive dietary availability. In this article, we review the clinical and experimental evidence for the possible benefits and risks of ingestion of estrogenic isoflavones throughout the life span, and highlight areas needing further elucidation.
authors.affiliation: Comparative Medicine Clinical Research Center, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27157-1040 USA.
authors.forename: T B
authors.initials: TB
authors.lastname: Clarkson
authors.forename: M S
authors.initials: MS
authors.lastname: Anthony
authors.forename: C L
authors.initials: CL
authors.lastname: Hughes