[Study on the distribution and risk factors of hypertension among children: a cohort study].
OBJECTIVE
To explore the association between hypertension and the tendency of change among children,so as to lay a foundation for the prevention and control of hypertension.


METHODS
Based on findings from the prevalence survey that carried out in September 1999 in Daqing of Heilongjiang province. New admission children were selected as subjects to conduct a five-year cohort study. All the subjects were interviewed with questionnaires and their blood specimens were collected for biochemical analysis. All data were analyzed using SPSS 10.0 software. Results The prevalence of hypertension among 447 children was found 2.01% at the baseline study but increased to 5.37% in the fifth year. During a five year period, the systolic pressure level among children increased from (100.65 +/- 11.62)mmHg (1 mm Hg = 0.133 kPa) to (106.67 +/- 9.29) mm Hg,while the diastolic pressure level was from (66.27 +/- 11.31) mm Hg to (70.28 +/- 7.98) mm Hg and showed significant difference between boys and girls. There were association between hypertension and family history, body mass index (BMI), triglyceride, insulin, insulin resistance index while insulin sensitivity index and family history, BMI and insulin sensitivity index appeared to be the important factors. Children under this study were divided to 'with family history or without' and then every group was divided to 'with over weight-obesity or normal'. Obesity and insulin sensitivity seemed the key risk factors on hypertension. Descent of insulin sensitivity was an independent risk factor.


CONCLUSIONS
The level of blood tension among children in Daqing city was higher than that from the national data. The present study confirmed that over-weight,obesity, heredity and insulin resistance were the risk factors of hypertension while insulin resistance was related to hypertension. The interaction of these risk factors was independent or correlated to each other.
Wang
Shuo
S
School of Public Health, Harbin Medical University, Harbin 150086, China.
An
Ya-li
YL
Wang
Jin-ping
JP
Jiang
Ya-yun
YY
Xing
Yan
Y
Wang
Ju
J
Xiang
Qian
Q
Xu
Yuan-yuan
YY
Tian
Wen-jing
WJ
Liu
Sheng-yuan
SY
Xing
Xiao-yan
XY
Li
Ming
M
Liu
Xue-li
XL
Zhang
Jing-ling
JL
Xiao
Jian-zhong
JZ
Hu
Ying-hua
YH
Peng
Chong
C
Li
Guang-wei
GW
Wang
Bin-you
BY
D001794:Blood Pressure; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D007333:Insulin Resistance; D008297:Male; D050177:Overweight / Q000150:complications; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides