title: [Detection of periodontal pathogens in coronary atherosclerotic plaques].
abstract: OBJECTIVE
  To explore the possible correlation between coronary heart disease and periodontitis.
  
  
  METHODS
  Subgingival plaque samples and coronary atherosclerotic plaques were harvested from a total of 31 patients with periodontitis who scheduled for coronary artery bypass surgery. The bacteria DNA was obtained from subgingival plaque samples and coronary atherosclerotic plaques using the chelex-100 method. The extracted DNA was examined using the polymerase chain reaction (PCR) technique.
  
  
  RESULTS
  In coronary atherosclerotic plaques samples from the 31 patients, Porphyromonas gingivalis (Pg, 38.7%), Actinobacillus actinomycetemcomitans (Aa, 0%), Fusobacterium nucleatum (Fn, 22.6%), Prevotella intermedia (Pi, 12.9%), Bacteroides forsythus (Bf, 38.7%) were detected. The concordant presence of the same periodontal bacteria DNA in subgingival plaques and in coronary atherosclerotic plaques in the same patient was Pg 5 (16.1%), Aa 0 (0%), Pi 2 (6.5%), Fn 4 (12.9%) and Bf 8 (25.8%).
  
  
  CONCLUSIONS
  The presence of periodontal bacteria DNA in coronary atherosclerotic plaques could indicate that periodontal pathogenic bacteria may play a role in the coronary heart disease process.
authors.affiliation: Department of Stomatology, First Affiliated Hospital, Xinjiang Medical University, Urümqi 830054, China.
authors.forename: Liang-jun
authors.initials: LJ
authors.lastname: Zhong
authors.forename: Yuan-ming
authors.initials: YM
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
authors.forename: Abdu Rehaman
authors.initials: AR
authors.lastname: Murat
authors.forename: Shabit
authors.initials: S
authors.lastname: Askar
mesh_terms: D000328:Adult; D000368:Aged; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D003324:Coronary Artery Disease / Q000382:microbiology*; D005260:Female; D016967:Fusobacterium nucleatum / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000382:microbiology*; D058226:Plaque, Atherosclerotic / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D018713:Prevotella intermedia / Q000302:isolation & purification