title: [The surgical treatment of renal cell carcinoma metastases to the vertebrae: intra-operative anesthesia related problems].
abstract: OBJECTIVE
  Analysis of the intra-operative anesthesia related problems were compared during intra-lesional or extra-lesional surgeries for patients with metastatic renal cell carcinoma to the spine.
  
  
  METHODS
  We retrospectively collected and analyzed the hemodynamic data on 30 patients who had undergone surgical intervention. Twenty patients had an intra-lesional excision of the metastatic lesion in the vertebra, whereas for the rest, an en-bloc wide or marginal margin resection was carried out.
  
  
  RESULTS
  The surgical time for the en-bloc resections was much longer, and thus also the exposure to the anesthesia, but lesser variability within the data on blood pressure and pulse as compared with intra-lesional curettage. There was also more blood loss with the intra-lesional surgeries.
  
  
  CONCLUSIONS
  En-bloc resections of the vertebral tumors not only give better oncological local control, but also have less compromising effects on the patient, especially with respect to the intra-operative hemodynamics. In selected cases, en-bloc resections present a good option of treatment in vertebral metastases, and especially in highly vascular tumors such as the renal cell carcinoma metastases.
authors.affiliation: UO di Ortopedia e Traumatologia, Chirurgia del Rachide, Ospedale Maggiore C.A. Pizzardi, Bologna, Italia.
authors.forename: M
authors.initials: M
authors.lastname: Cappuccio
authors.forename: A
authors.initials: A
authors.lastname: Gasbarrini
authors.forename: L
authors.initials: L
authors.lastname: Bandello
authors.forename: E
authors.initials: E
authors.lastname: Focarazzo
authors.forename: S
authors.initials: S
authors.lastname: Bandiera
authors.forename: F
authors.initials: F
authors.lastname: De Iure
authors.forename: G Barbanti
authors.initials: GB
authors.lastname: Bròdano
authors.forename: S
authors.initials: S
authors.lastname: Boriani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000758:Anesthesia / Q000009:adverse effects* / Q000379:methods; D002292:Carcinoma, Renal Cell / Q000556:secondary / Q000601:surgery*; D003646:Debridement / Q000379:methods; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D007680:Kidney Neoplasms / Q000473:pathology*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000601:surgery*; D016896:Treatment Outcome