About human tumor antigens to be used in immunotherapy.
The choice of antigens to be used in cancer immunotherapy remains a crucial and difficult issue. This review highlights some properties of the different groups of human tumor antigens recognized by T lymphocytes, focusing on parameters that should influence this choice, such as tumor specificity and level of antigen expression.
Lucas
S
S
de Duve Institute and Université catholique de Louvain, B-1200 Brussels, Belgium. sophie.lucas@uclouvain.be
Coulie
P G
PG
D000951:Antigens, Neoplasm / Q000276:immunology*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007167:Immunotherapy; D009154:Mutation; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*
D000951:Antigens, Neoplasm