A prospective analysis of testicular androgenic function in recipients of a renal allograft.
Eighteen adult males with end stage renal disease (ESRD) were studied to determine the serum levels of gonadotropins (LH and FSH), prolactin (PRL) and testosterone. All of the patients were studied longitudinally while undergoing maintenance hemodialysis (HD) and six months after renal transplantation. Prior to transplantation, significantly high levels of gonadotropins and PRL were observed. During HD the serum testosterone levels tended to be subnormal in most of the uremic patients and low normal in some of the subjects. Renal transplantation led to a significant improvement (P < 0.05) in serum testosterone. Elevated gonadotropin and PRL levels observed in patients on HD returned to the normal range in most of the patients after successful renal transplantation.
Yadav
Rajiv
R
Department of Urology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Mehta
S N
SN
Kumar
A
A
Guleria
S
S
Seenu
V
V
Tiwari
S C
SC
D000293:Adolescent; D000328:Adult; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D006966:Hyperprolactinemia / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery / Q000628:therapy; D016030:Kidney Transplantation / Q000502:physiology*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D006435:Renal Dialysis; D013737:Testis / Q000503:physiopathology*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone