"APUD" cells: fact and fiction.
Pearse's "APUD" cell theory helps define the ontogeny and differentiation programs of small polypeptide hormone-secreting cells of diverse tissue origins. Cells with such features may arise through one of multiple related pathways of epithelial cell differentiation ongoing in tissues of all embryonic lineages.
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Oncology Center and Department of Medicine, The Johns Hopkins University Medical Institutions, Baltimore, MD 21231, USA.