Electrochromatography in microchips packed with conventional reversed-phase silica particles.
This paper shows the applicability of a disposable and inexpensive microfluidic chip for electrochromatographic separations. The chip, recently developed by us for chip-based LC, was fabricated from PDMS incorporating conventional chromatographic RP silica particles (C18) without the use of frits. Three cephalosporin antibiotics were used to demonstrate the applicability of the chip-based chromatographic packing for electrochromatographic determinations. The used sample injection method utilizes hydrodynamic pressure, thereby, reducing the propensity for sample bias during the injection.
Gaspar
Attila
A
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA, USA. gaspara@tigris.klte.hu
Hernandez
Lilia
L
Stevens
Schetema
S
Gomez
Frank A
FA
D046209:Electrophoresis, Microchip / Q000379:methods*; D012822:Silicon Dioxide
D012822:Silicon Dioxide