[Urolithiasis and nephropathy complicated with gout].
Urolithiasis is a clinically important complication of gout. For effective prevention of this complication, it is necessary to comprehend the factors known to be important in its development. Our analysis of stones in gout patients revealed that the incidence of common calcium salt stones was over 60%, while that of uric acid stones was only about 30%. This implies that the disruption of uric acid metabolism promotes not only uric acid stones but also calcium salt stones. Twenty-four per cent of gout patients showed acidic urine throughout the day. Urinary management, which consists of hydration and alkalization of urine, is indispensable along with control of the serum urate level in the treatment of gout.
Shimizu
Toru
T
Department of Rheumatology, Midorigaoka Hospital.
D006073:Gout / Q000150:complications* / Q000628:therapy / Q000652:urine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D024821:Metabolic Syndrome / Q000150:complications; D051437:Renal Insufficiency / Q000209:etiology; D014527:Uric Acid / Q000378:metabolism; D052878:Urolithiasis / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control / Q000628:therapy
D014527:Uric Acid