title: Electrochromatography in microchips packed with conventional reversed-phase silica particles.
abstract: This paper shows the applicability of a disposable and inexpensive microfluidic chip for electrochromatographic separations. The chip, recently developed by us for chip-based LC, was fabricated from PDMS incorporating conventional chromatographic RP silica particles (C18) without the use of frits. Three cephalosporin antibiotics were used to demonstrate the applicability of the chip-based chromatographic packing for electrochromatographic determinations. The used sample injection method utilizes hydrodynamic pressure, thereby, reducing the propensity for sample bias during the injection.
authors.affiliation: Department of Chemistry and Biochemistry, California State University, Los Angeles, CA, USA. gaspara@tigris.klte.hu
authors.forename: Attila
authors.initials: A
authors.lastname: Gaspar
authors.forename: Lilia
authors.initials: L
authors.lastname: Hernandez
authors.forename: Schetema
authors.initials: S
authors.lastname: Stevens
authors.forename: Frank A
authors.initials: FA
authors.lastname: Gomez
mesh_terms: D046209:Electrophoresis, Microchip / Q000379:methods*; D012822:Silicon Dioxide
chemical_list: D012822:Silicon Dioxide