title: Plasmapheresis in asparaginase-induced hypertriglyceridemia.
abstract: BACKGROUND
  Asparaginase is an essential component of the chemotherapy regimens during the induction and intensification phases for acute lymphoblastic leukemia and lymphoblastic lymphoma. The administration of asparaginase can cause elevation of the triglyceride levels.
  
  
  METHODS
  This study reports the case of an adult patient presenting with acute pancreatitis secondary to severe hypertriglyceridemia after asparaginase treatment during the consolidation phase of lymphoblastic lymphoma. This condition was successfully treated with plasmapheresis.
  
  
  CONCLUSIONS
  Our case demonstrates that plasmapheresis in severe cases of hypertriglyceridemia offers a safe and efficient treatment option for symptomatic patients.
authors.affiliation: Department of Pathology and Laboratory Medicine and Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Kfoury-Baz
authors.forename: Rabih A
authors.initials: RA
authors.lastname: Nassar
authors.forename: Rita F
authors.initials: RF
authors.lastname: Tanios
authors.forename: Zaher K
authors.initials: ZK
authors.lastname: Otrock
authors.forename: Amira M
authors.initials: AM
authors.lastname: Youssef
authors.forename: Costantine
authors.initials: C
authors.lastname: Albany
authors.forename: Ali
authors.initials: A
authors.lastname: Bazarbachi
authors.forename: Ziad M
authors.initials: ZM
authors.lastname: Salem
mesh_terms: D000328:Adult; D000818:Animals; D001215:Asparaginase / Q000378:metabolism*; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood / Q000201:enzymology*; D008297:Male; D010956:Plasmapheresis / Q000009:adverse effects* / Q000295:instrumentation*; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D001215:Asparaginase