Postmenopausal estrogen therapy, 1995.
Estrogen therapy offers women important benefits, including the potential prolongation of life by prevention of coronary heart disease (CHD) and osteoporotic fractures, and improvement of life by prevention of menopausal symptoms. Not all women can accept the potential side effects and risks, however, which include uterine bleeding, cystic mastitis, fluid retention, and increased risk of uterine cancer and breast cancer. Thus, the benefits and risks must be patiently weighed for each individual, and the alternatives of no treatment or other treatment should be clear. We review here the pertinent information that now makes these decisions quite sound.
Lufkin
E G
EG
Department of Endocrinology and Internal Medicine, Section of Reproductive Endocrinology and Infertility, Mayo Clinic, Rochester, MN 55905, USA.
Ory
S J
SJ