Cholesterol-lowering activity of plant sterol-egg yolk lipoprotein complex in rats.
Free plant sterols cannot be dissolved in oil or water. Using free plant sterols and egg yolks, we developed a plant sterol-egg yolk lipoprotein complex (PSY) that can be dispersed in water and considered suitable for use in processed foods. The cholesterol-lowering activity of PSY was equal to that of free plant sterols and plant sterol esters. Consumption of a freeze-dried PSY-containing omelet reduced serum and hepatic cholesterol concentrations. The results suggest that PSY has cholesterol-lowering activity equivalent to that of free plant sterols and plant sterol esters. Moreover, the cholesterol-lowering activity of PSY was maintained in processed foods.
Matsuoka
Ryosuke
R
R&D Division, Q.P. Corporation, Goka-machi, Sashima-gun, Ibaraki, Japan. ryosuke_matsuoka@kewpie.co.jp
Muto
Ayano
A
Kimura
Mamoru
M
Hoshina
Ryosuke
R
Wakamatsu
Toshio
T
Masuda
Yasunobu
Y
D000818:Animals; D002784:Cholesterol / Q000097:blood*; D004032:Diet; D004530:Egg Yolk / Q000378:metabolism*; D004952:Esters / Q000032:analysis; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008297:Male; D010840:Phytosterols / Q000032:analysis / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D004952:Esters; D008055:Lipids; D008074:Lipoproteins; D010840:Phytosterols; D002784:Cholesterol