title: Comparison of single versus double intrauterine insemination.
abstract: OBJECTIVE
  To compare the outcomes of single versus double intrauterine insemination.
  
  
  METHODS
  This prospective randomized study was carried out in 100 infertile patients. One intrauterine insemination was applied 36 hours after human chorionic gonadotropin (hCG) injection to 50 patients in the first group. To 50 patients in the second group, two intrauterine inseminations were applied, of which the first was applied 24 hours after and the second 48 hours after the hCG injection.
  
  
  RESULTS
  In the first group, pregnancies were detected in eight patients (pregnancy rate per patient was 16%, pregnancy rate per cycle was 10.6%). In the second group, pregnancies were detected in five patients (pregnancy rate per patient was 10%, pregnancy rate per cycle was 6.4%). There was no statistically significant difference between the two groups ( p > 0.05).
  
  
  CONCLUSIONS
  Single intrauterine insemination can be considered to be more reasonable than double intrauterine insemination treatment, taking into consideration the economic cost and the psychologic trauma to the patients. However, further studies with larger sample sizes are needed in order to reveal any actual differences between the two methods.
authors.affiliation: Department of Obstetrics and Gynecology, Medical Faculty of Meram, Selcuk University, Konya, Turkey. kazimgezginc@hotmail.com
authors.forename: Kazim
authors.initials: K
authors.lastname: Gezginç
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Görkemli
authors.forename: Cetin
authors.initials: C
authors.lastname: Celik
authors.forename: Rengin
authors.initials: R
authors.lastname: Karatayli
authors.forename: M Nedim
authors.initials: MN
authors.lastname: Ciçek
authors.forename: M Cengiz
authors.initials: MC
authors.lastname: Olakoglu
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D007248:Infertility, Male / Q000628:therapy; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012102:Reproductive Control Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D006063:Chorionic Gonadotropin; D012102:Reproductive Control Agents