title: Histopathological comparison of pulmonary artery lesions between raccoon dogs (Nyctereutes procyonoides) and domestic dogs experimentally infected with Dirofilaria immitis.
abstract: Five raccoon dogs (Nyctereutes procyonoides) and two domestic dogs (Canis familiaris) were subcutaneously infected with 100 infective larvae (L3) of Dirofilaria immitis. Two and five worms, respectively, were collected from two of three raccoon dogs. Villous endarteritis was found in the raccoon dog with five worms and two dogs at 116 days after infection. The number of recovered worms in the raccoon dogs was significantly smaller than that of the domestic dogs having 22 and 29 worms, while histopathological features and the severity of the lesions in the raccoon dogs were similar to those in the domestic dogs. The vascular lesions in two chronically-infected raccoon dogs turned into much severe at 565 and 590 days after inoculation.
authors.affiliation: Research Institute of Biosciences, Azabu University, Sagamihara, Kanagawa 229-8501, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawabata
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Nakagaki
authors.forename: Motonobu
authors.initials: M
authors.lastname: Yoshida
authors.forename: Kinji
authors.initials: K
authors.lastname: Shirota
mesh_terms: D000818:Animals; D004183:Dirofilaria immitis; D004184:Dirofilariasis / Q000473:pathology*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D011651:Pulmonary Artery / Q000473:pathology*; D046031:Raccoon Dogs