Single nucleotide polymorphism typing of Bacillus anthracis from Sverdlovsk tissue.
A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient's B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.
Okinaka
Richard T
RT
Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
Henrie
Melinda
M
Hill
Karen K
KK
Lowery
Kristin S
KS
Van Ert
Matthew
M
Pearson
Talima
T
Schupp
James
J
Kenefic
Leo
L
Beaudry
Jodi
J
Hofstadler
Steven A
SA
Jackson
Paul J
PJ
Keim
Paul
P
D000881:Anthrax / Q000453:epidemiology* / Q000382:microbiology; D000942:Antigens, Bacterial / Q000235:genetics; D001408:Bacillus anthracis / Q000145:classification* / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry; D005838:Genotype; D006801:Humans; D019570:Inhalation Exposure; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D012426:Russia / Q000453:epidemiology
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004269:DNA, Bacterial; C030325:anthrax toxin