title: [Social and economic impact of chicken pox vaccine at 15 months of age. Castile and Leon, Spain, 2004].
abstract: BACKGROUND
  Chicken pox is a mainly childhood contagious disease caused by the Varicella Zoster Virus which gives rise to major healthcare and social costs. In 2005, Castile and Leon added chicken pox vaccine injections to its childhood vaccination schedule for eleven year-olds subject to coming down with this disease. This strategy does not modify the major mobility generated thereby at younger ages. This study is aimed at evaluating the profitability of systematic vaccination for chicken pox in infants 15 months of age in Castile and Leon.
  
  
  METHODS
  An economic cost-benefit evaluation has been set out by jeans of a decision-making tree. A fictitious cohort of 100,000 children in Castile and Leon having reached 15 months of age in 2004 is studied, to whom the chicken pox vaccine would be administered in conjunction with the mumps, measles, rubella vaccines. This study is approached from the social standpoint. The time horizon selected was that of up until the study cohort was to reach 15 years of age, applying a 3% discount rate. A sensitivity analysis was made for evaluating the uncertainty of some variables...
  
  
  RESULTS
  The cost-benefit ratio of adding this vaccine to the childhood vaccination schedule amounts to 1.23.
  
  
  CONCLUSIONS
  From the social standpoint, administering chicken pox vaccine in conjunction with the mumps, measles, rubella vaccines show itself to be profitable. The profitability is modified both if a second dose of vaccine is added as well as if only the direct healthcare costs are analyzed.
authors.affiliation: Servicio de Medicina Preventiva y Salud Pública, Hospital Clínico Universitario, Valladolid. albertoprz@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Rubio
authors.forename: J J
authors.initials: JJ
authors.lastname: Castrodeza Sanz
authors.forename: M
authors.initials: M
authors.lastname: Gil Costa
authors.forename: F J
authors.initials: FJ
authors.lastname: Luquero Alcalde
authors.forename: J
authors.initials: J
authors.lastname: Eiros Bouza
authors.forename: R
authors.initials: R
authors.lastname: Ortiz de Lejarazu
mesh_terms: D000293:Adolescent; D002644:Chickenpox / Q000191:economics* / Q000517:prevention & control*; D019433:Chickenpox Vaccine / Q000008:administration & dosage / Q000191:economics*; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D006801:Humans; D007223:Infant; D011584:Psychology; D013030:Spain / Q000453:epidemiology; D014611:Vaccination / Q000191:economics* / Q000706:statistics & numerical data*
chemical_list: D019433:Chickenpox Vaccine