title: The relationship between body mass index and postoperative mortality from critical illness.
abstract: BACKGROUND
  Conflicting data exist regarding the effect of body mass index (BMI) on postoperative mortality from critical illness. Few studies have examined this issue in surgical patients specifically. We tested the hypothesis that BMI is associated with mortality from surgical critical illness.
  
  
  METHODS
  Consecutive admissions to a university surgical intensive care unit (SICU) were analyzed from January 2005-August 2006. Admission BMI was analyzed as both a five-level categorical (underweight, <18.5 kg/m2; normal weight, 18.5-24.9 kg/m2; overweight, 25.0-29.9 kg/m2; obese, 30.0-39.9 kg/m2; morbidly obese, > or =40 kg/m2) and dichotomous (> or =40 kg/m2 vs. <40 kg/m2) variable among all patients as well as a subgroup of patients with a SICU length of stay (ULOS) > or =4 days. Multivariable logistic regression models were fit to determine the independent effect of BMI group on SICU mortality.
  
  
  RESULTS
  The total sample size was 946, with 490 patients admitted to the SICU for > or =4 days (51.8%). Of the variables tested, age, acute physiology and chronic health evaluation III score, gender, diabetes mellitus, and need for insulin infusion varied significantly among the five BMI groups. After adjustment for these variables, BMI was not predictive of mortality when analyzed as either a five-level categorical or dichotomous variable, regardless of ULOS.
  
  
  CONCLUSIONS
  BMI is not related to mortality of surgical critical illness. Several factors, including modern ICU care, may mitigate the risks of obesity in the SICU.
authors.affiliation: Department of Surgery, Weill Cornell Medical College, New York, NY, USA. frp9005@med.cornell.edu
authors.forename: Fredric M
authors.initials: FM
authors.lastname: Pieracci
authors.forename: Lynn
authors.initials: L
authors.lastname: Hydo
authors.forename: Alfons
authors.initials: A
authors.lastname: Pomp
authors.forename: Soumitra R
authors.initials: SR
authors.lastname: Eachempati
authors.forename: Jian
authors.initials: J
authors.lastname: Shou
authors.forename: Philip S
authors.initials: PS
authors.lastname: Barie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D015897:Comorbidity; D016638:Critical Illness / Q000401:mortality* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000453:epidemiology*; D009767:Obesity, Morbid / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D011184:Postoperative Period; D012372:ROC Curve