Choroidal plasmacytoma in a patient with multiple myeloma. Diagnosis by fine-needle aspiration biopsy.
BACKGROUND
To report a case of a secondary plasmacytoma of the choroid.


METHODS
Interventional case report with cytopathologic correlation.


RESULTS
A 61-year-old male with a breast nodule and a 2-year history of multiple myeloma developed blurred vision and was found to have three confluent, ill-defined areas of choroidal thickening in the left eye. Cytopathology and immunohistochemistry of a transocular fine-needle aspiration biopsy of the largest lesion revealed atypical plasma cells diagnostic of plasmacytoma. Following external beam radiotherapy the choroidal tumors resolved completely.


CONCLUSIONS
Secondary plasmacytoma, despite its rarity, should be included in the differential diagnosis of amelanotic choroidal tumors, particularly in patients with multiple myeloma. Radiotherapy is an effective treatment.
Palamar
Melis
M
Ocular Oncology Service Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA.
Shields
Carol L
CL
Ghassemi
Fariba
F
Ehya
Hormoz
H
Shields
Jerry A
JA
D044963:Biopsy, Fine-Needle; D002830:Choroid Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis*; D010954:Plasmacytoma / Q000473:pathology* / Q000532:radiotherapy