Distinct functional domains on the insulin receptor beta-subunit Do they provide a molecular basis for "selective" insulin resistance?
The insulin receptor is seen as having a number of structurally and functionally distinct domains. Modifications of particular domains may lead to the partial crippling of receptor function, which could give rise to selective insulin-resistant states.
Houslav
M D
MD
Molecular Pharmacology Group, Institute of Biochemistry, University of Glasgow, Glasgow G12 8QQ, UK.