title: Three-year anatomic and visual outcomes after vitrectomy for stage 4B retinopathy of prematurity.
abstract: OBJECTIVE
  To assess anatomic and visual outcome following vitrectomy for stage 4B retinopathy of prematurity (ROP) after 3 years follow-up.
  
  
  METHODS
  Retrospective analysis of 56 eyes (46 infants) with stage 4B ROP-related retinal detachment. Eyes underwent either lens-sparing vitrectomy (LSV) or combined lensectomy and vitrectomy (LV). Visual outcome after a minimum follow-up of 36 months was ascertained by using either Teller or Snellen acuities, or sweep visual evoked potential.
  
  
  RESULTS
  LSV was performed in 42.9% and LV in 57.1% of eyes. Retinal reattachment was achieved in 73.2% overall (LV 71.8% versus LSV 75%) (P = 0.96). Ambulatory vision (VA better than 20/1900) and near reading vision (better than 20/800) were attained in 97.4% and 42.8% of eyes respectively. Attached retina, LSV, and pretreatment with retinal ablation were associated with a higher incidence of near reading or better vision compared to detached (P < 0.001), undergoing LV (P < 0.001), and non pretreated eyes (P = 0.011).
  
  
  CONCLUSIONS
  After 3 years, more than 40% of eyes operated for ROP stage 4B in this series had a visual acuity compatible for near reading or better. Eyes undergoing LSV and with prior peripheral retinal ablation had better visual outcomes.
authors.affiliation: Research Institute of Ophthalmology, Cairo, Egypt.
authors.forename: Ehab N
authors.initials: EN
authors.lastname: El Rayes
authors.forename: Anand
authors.initials: A
authors.lastname: Vinekar
authors.forename: Antonio
authors.initials: A
authors.lastname: Capone
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007908:Lens, Crystalline / Q000601:surgery; D008297:Male; D012160:Retina / Q000503:physiopathology*; D012163:Retinal Detachment / Q000601:surgery*; D012178:Retinopathy of Prematurity / Q000145:classification / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*; D014821:Vitrectomy