title: COUP-TF an orphan member of the steroid/thyroid hormone receptor superfamily.
abstract: COUP-TFs are orphan members of the steroid/thyroid hormone receptor superfamily. They are transcription factors that are highly conserved across species and have a wide spectrum of binding specificity. In tissue cultures, COUP-TFs repress the transactivation function of several other members of the steroid/thyroid hormone receptor superfamily, and they also negatively regulate the transcription from promoters of many other genes. The expression profile of COUP-TFs in several species suggests that they play an important role in development and differentiation.
authors.affiliation: The Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Qiu
authors.forename: S Y
authors.initials: SY
authors.lastname: Tsai
authors.forename: M J
authors.initials: MJ
authors.lastname: Tsai