title: Demyelinating disease in patients with myasthenia gravis.
abstract: Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.
authors.affiliation: Neurology and Neurosurgery Department, Federal University of São Paulo, São Paulo, SP, Brazil. denisbichuetti@globo.com
authors.forename: Denis Bernardi
authors.initials: DB
authors.lastname: Bichuetti
authors.forename: Tatiane Martins de
authors.initials: TM
authors.lastname: Barros
authors.forename: Enedina Maria Lobato
authors.initials: EM
authors.lastname: Oliveira
authors.forename: Marcelo
authors.initials: M
authors.lastname: Annes
authors.forename: Alberto Alain
authors.initials: AA
authors.lastname: Gabbai
mesh_terms: D000328:Adult; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications*; D009471:Neuromyelitis Optica / Q000175:diagnosis / Q000209:etiology; D012008:Recurrence