title: Feasibility of global measles eradication after interruption of transmission in the Americas.
abstract: Measles is one of the most infectious diseases. Before the introduction of the measles vaccine, nearly all children contracted measles. By the end of the 1980s, most countries of the world had incorporated the measles vaccine into their routine vaccination programs. Globally, some 345,000 deaths due to measles still occur every year. Eradication of measles would play an important role in improving child survival. The goal to eradicate measles from the Americas was set by the Pan-American Sanitary Conference in 1994. Progress to date has been remarkable. Measles is no longer an endemic disease in the Americas and interruption of transmission has been documented in most countries. As of December 2007, 5 years have elapsed since the detection of the last endemic case in Venezuela in November 2002. This experience demonstrates that interruption of measles transmission can be achieved and sustained over a long period of time. Global eradication should be feasible if the appropriate strategies are implemented. Even in a new paradigm in which eradication is not followed by the discontinuation of vaccination, eradication of measles should be a good investment to avoid expensive epidemics and save those children that would potentially die due to infection with the measles virus. It is not only a dream to think that we will see a world free of measles by the year 2015.
authors.affiliation: Sabin Vaccine Institute, Washington, DC 20006, USA. ciro.dequadros@sabin.org
authors.forename: Ciro A
authors.initials: CA
authors.lastname: de Quadros
authors.forename: Jon Kim
authors.initials: JK
authors.lastname: Andrus
authors.forename: M Carolina
authors.initials: MC
authors.lastname: Danovaro-Holliday
authors.forename: Carlos
authors.initials: C
authors.lastname: Castillo-Solórzano
mesh_terms: D014943:Global Health; D006801:Humans; D017589:Immunization Programs / Q000379:methods / Q000639:trends; D007843:Latin America / Q000453:epidemiology; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission*; D008458:Measles Vaccine / Q000627:therapeutic use; D013020:South America / Q000453:epidemiology
chemical_list: D008458:Measles Vaccine