Endocrine and metabolic abnormalities in adolescents with a PCOS-like condition: consequences for adult reproduction.
The polycystic ovary syndrome (PCOS) has a perimenarcheal onset. Increased luteinizing hormone (LH) and androgen concentrations are common among anovulatory adolescents and some also have hyperinsulinemia. Many will later have normal ovulatory cycles, whereas others with several co-existing abnormalities will develop full-blown PCOS with menstrual cycle irregularities and infertility in adulthood.
Apter
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Sexual Health Clinic, Family Federation of Finland, Helsinki, Finland.