[Recent progress in epilepsy in neuropathology].
Epilepsy is a common cerebral disease, and may cause sudden death. Although electric activity study of epileptic brain had been emphasized in the past, the neuropathological study of epilepsy has become a main focus in clinical and forensic medicine recently. This article reviews the recent progress in neuropathology of epilepsy including developmental disorder, abnormal tumoral proliferation, hippocampal sclerosis, dual pathological alteration, and mossy fiber sprouting. Its significance in forensic medicine, particularly for the diagnosis of sudden unexpected death in epilepsy, is discussed.
Zhang
Lei
L
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. hanwen539@163.com
Zhang
Yang
Y
Fan
Fan
F
Jie
Ya
Y
Zhu
Shao-Hua
SH
Liu
Liang
L
Zhou
Yi-Wu
YW
D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D002423:Cause of Death; D003645:Death, Sudden / Q000209:etiology*; D004827:Epilepsy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D049429:Forensic Pathology; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D054220:Malformations of Cortical Development / Q000150:complications / Q000473:pathology; D012598:Sclerosis / Q000150:complications / Q000473:pathology