title: Catalase-negative Staphylococcus aureus strain with point mutations in the katA gene.
abstract: Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, including one leading to a substitution of key histidine 58 by a tyrosine.
authors.affiliation: Service de Microbiologie, Université de Caen Basse-Normandie, CHU Côte de Nacre, 14033 Caen cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Piau
authors.forename: J
authors.initials: J
authors.lastname: Jehan
authors.forename: R
authors.initials: R
authors.lastname: Leclercq
authors.forename: C
authors.initials: C
authors.lastname: Daurel
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000150:complications; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002374:Catalase / Q000235:genetics* / Q000378:metabolism; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis / Q000382:microbiology*; D017354:Point Mutation; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000201:enzymology* / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D002374:Catalase