[Prophylaxis of infective endocarditis: trends and new recommendations].
The rationale having led to the profound change in the guidelines on the prevention of endocarditis is presented. The current trend to abandoning systematic antibiotic prophylaxis in patients at risk for infective endocarditis is in fact based upon a sound scientific background. Systematic antibiotic prophylaxis remains necessary, however, in the category of patients at very high risk.
Duval
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Service des maladies infectieuses et tropicales, hôpital Bichat-Claude-Bernard, 46, rue Henri-Huchard, 75877 Paris cedex 18, France. xavier.duval@bch.aphp.fr
D019072:Antibiotic Prophylaxis; D004696:Endocarditis / Q000517:prevention & control*; D006801:Humans; D018570:Risk Assessment