title: Polysaccharides fraction isolated from ginkgo biloba folium: immunopharmacological properties.
abstract: Many macromolecular compounds of vegetal polysaccharides type develop important immunostimulatory properties.
  
  
  METHODS
  Crude macromolecular fraction was isolated from the leaves of Ginkgo biloba L. (codified as PGfol) harvested from Botanical Gardens of Iaşi, Romania. The hot water extract was partially purified and submitted to chemical and immunopharmacological studies. The immunostimulatory activity of PGfol was further investigated by a series of tests on rats: phagocytosis capacity of PMN cells by NBT test, serum complement activity and determination of the activity of splenic T-lymphocytes.
  
  
  RESULTS
  PGfol has a good immunostimulatory activity which is equal or higher to Levamisole (positive control).
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, "Gr.T. Popa" University of Medicine and Pharmacy, Iaşi.
authors.forename: Monica
authors.initials: M
authors.lastname: Hăncianu
authors.forename: M
authors.initials: M
authors.lastname: Pavelescuz
authors.forename: Anca
authors.initials: A
authors.lastname: Miron
authors.forename: Ana Clara
authors.initials: AC
authors.lastname: Aprotosoaie
authors.forename: Em
authors.initials: E
authors.lastname: Grigorescu
authors.forename: Cătălina
authors.initials: C
authors.lastname: Lupuşoru
authors.forename: Ursula
authors.initials: U
authors.lastname: Stănescu
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D004195:Disease Models, Animal; D020441:Ginkgo biloba / Q000737:chemistry; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy* / Q000276:immunology; D007978:Levamisole / Q000494:pharmacology / Q000627:therapeutic use; D010587:Phagocytosis / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D010936:Plant Extracts; D011134:Polysaccharides; D007978:Levamisole