Intake of fruit, vegetables, and fruit juices and risk of diabetes in women.
OBJECTIVE
The purpose of this study was to examine the association between fruit, vegetable, and fruit juice intake and development of type 2 diabetes.


METHODS
A total of 71,346 female nurses aged 38-63 years who were free of cardiovascular disease, cancer, and diabetes in 1984 were followed for 18 years, and dietary information was collected using a semiquantitative food frequency questionnaire every 4 years. Diagnosis of diabetes was self-reported.


RESULTS
During follow-up, 4,529 cases of diabetes were documented, and the cumulative incidence of diabetes was 7.4%. An increase of three servings/day in total fruit and vegetable consumption was not associated with development of diabetes (multivariate-adjusted hazard ratio 0.99 [95% CI 0.94-1.05]), whereas the same increase in whole fruit consumption was associated with a lower hazard of diabetes (0.82 [0.72-0.94]). An increase of 1 serving/day in green leafy vegetable consumption was associated with a modestly lower hazard of diabetes (0.91 [0.84-0.98]), whereas the same change in fruit juice intake was associated with an increased hazard of diabetes (1.18 [1.10-1.26]).


CONCLUSIONS
Consumption of green leafy vegetables and fruit was associated with a lower hazard of diabetes, whereas consumption of fruit juices may be associated with an increased hazard among women.
Bazzano
Lydia A
LA
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA. lbazzano@tulane.edu
Li
Tricia Y
TY
Joshipura
Kamudi J
KJ
Hu
Frank B
FB
D000328:Adult; D001628:Beverages; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000517:prevention & control*; D004032:Diet; D002149:Energy Intake; D005260:Female; D005638:Fruit; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D015999:Multivariate Analysis; D009726:Nurses; D016016:Proportional Hazards Models; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D014675:Vegetables