Anejaculation as the presenting feature of pituitary microadenoma.
OBJECTIVE
To describe the resolution of anejaculation associated with PRL excess by dopamine agonist treatment.


METHODS
Case report.


METHODS
Fertility clinic.


METHODS
Two men with anejaculation, in one case with associated infertility.


METHODS
Dopamine agonist treatment.


METHODS
Resolution of anejaculation and infertility.


RESULTS
Endocrine investigations in both men revealed low serum T, elevated PRL, and a pituitary microadenoma. Treatment with a dopamine agonist normalized serum hormone profiles and restored sexual function, with subsequent involution of the adenoma.


CONCLUSIONS
Prolactinoma manifesting as anejaculation is rare but responds readily to treatment with a dopamine agonist. Serum PRL should be measured in any man presenting with anejaculation.
Nair
Sasha
S
Fertility Associates, Ascot Hospital, Remuera, Auckland, New Zealand.
Milsom
Stella
S
D000328:Adult; D018491:Dopamine Agonists / Q000627:therapeutic use*; D004542:Ejaculation / Q000187:drug effects*; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D011388:Prolactin / Q000097:blood*; D015175:Prolactinoma / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D015854:Up-Regulation
D018491:Dopamine Agonists; D011388:Prolactin