title: Promoting the social value of research in Kenya: examining the practical aspects of collaborative partnerships using an ethical framework.
abstract: The ethics of research continue to attract considerable debate, particularly when that research is sponsored by partners from the North and carried out in the South. Ethical research should contribute to social value in the country where research is being carried out, but there is significant debate around how this might be achieved and who is responsible. The literature suggests that researchers might employ two inter-related strategies to maximise social value: collaborative partnerships with policy makers and communities from the outset of research, and dissemination of research results to participants, policy makers and implementers once the research is over. These areas have received relatively little empirical attention. In this study, we carried out 40 in-depth interviews to explore the role of collaborative partnerships in health research priority setting, and the way in which research findings are disseminated to aid policy making and implementation in Kenya. Interviewees included policy makers, researchers, policy implementers and representatives of organisations funding health reforms in Kenya. Two policy issues were drawn upon as tracers wherever possible: (1) the introduction of Artemesinin-based Combination Therapies (ACTs), an anti-malarial treatment policy; and (2) Haemophilus influenzae (Hib) vaccine for the prevention of pneumococcal diseases among children. The findings point to significant gaps in the 'research to policy to practice' pathway, particularly for national research institutions with a focus on clinical/biomedical research. These gaps reflect poorly effective partnerships among stakeholders and limit the potential social value of much research. While more investment is needed to establish strong structures for promoting and directing collaboration and partnership, how to target this investment is not entirely clear, especially in the context of the considerable power of the global health agenda and the research financing tied to it.
authors.affiliation: Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Wellcome Trust Research Programme, P.O. Box 43640, Nairobi, Kenya. lmbaabu@nairobi.kemri-wellcome.org
authors.forename: Geoffrey Mbaabu
authors.initials: GM
authors.lastname: Lairumbi
authors.forename: Sassy
authors.initials: S
authors.lastname: Molyneux
authors.forename: Robert W
authors.initials: RW
authors.lastname: Snow
authors.forename: Kevin
authors.initials: K
authors.lastname: Marsh
authors.forename: Norbert
authors.initials: N
authors.lastname: Peshu
authors.forename: Mike
authors.initials: M
authors.lastname: English
mesh_terms: D000047:Academies and Institutes; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000962:Antimalarials / Q000627:therapeutic use; D037621:Artemisinins / Q000627:therapeutic use; D003159:Community-Institutional Relations; D003299:Cooperative Behavior; D004359:Drug Therapy, Combination; D032984:Ethics, Research; D018073:Haemophilus Vaccines; D006291:Health Policy; D006801:Humans; D033181:Information Dissemination / Q000941:ethics*; D007407:Interviews as Topic; D007630:Kenya; D008288:Malaria / Q000188:drug therapy; D011050:Policy Making; D012945:Social Values
chemical_list: D000890:Anti-Infective Agents; D000962:Antimalarials; D037621:Artemisinins; D018073:Haemophilus Vaccines; C031327:artemisinin