[Transitional bladder cancer and occupational exposure. Accuracy assessment of a screening method based on structured interview].
The transitional bladder cancer is the most frequent urinary malignant neoplasm. The main risk factors are cigarette smoking, recurrent inflammatory diseases of the urinary tract, assumption of some drugs, familiarity and occupational exposure to aromatic amines and polycyclic aromatic hydrocarbons. The aim of this study is to assess the screening efficacy of a short structured interview to detect the possible occupational bladder cancer, to submit to the specialists evaluation. The sample of the study is represented by 100 subjects, hospitalized for transitional bladder cancer in the years 2004 and 2005 at the Department of Urology of the Ospedale di Circolo - Fondazione Macchi in Varese. Through the structured interview was possible to estimate two occupational exposure indexes: Length-Field Index (DS) and Length-Field-Job Index (DSM). The specialist's evaluation allowed to establish the occupational cancer origin. The analysis of the indexes' accuracy showed good operating characteristics with higher specificity and equal sensitivity for DSM in comparison to DS. Therefore the short structured interview should be considered as a valuable tool to identify urothelial carcinomas worthy of further evaluation of occupational specialist.
Borchini
R
R
Medicina del Lavoro e Preventiva, AO Ospedale di Circolo e Fondazione Macchi, Varese. rossana.borchini@uninsubria.it
Veronesi
G
G
Mombelli
S
S
Fava
C
C
Ferrario
M M
MM
D000328:Adult; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007407:Interviews as Topic / Q000379:methods; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis*; D016273:Occupational Exposure / Q000009:adverse effects*; D015203:Reproducibility of Results; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*