[Complications after lung transplantation: gastroenterological, hematological and cardiovascular involvement].
Intestinal perforation after lung transplantation is common in elderly patients with diverticulitis. The distal intestinal obstruction syndrome (DIOS) is a current complication in patients with cystic fibrosis. Myelosuppressive drugs as in most immunosuppressive regimens can cause cytopenia. Thrombotic microangiopathy is often caused by immunosuppressive regimen with a calcineurin-inhibitor in combination with a proliferation signal-inhibitor. Although renal failure and neurological symptoms are often additional side effects of the immunosuppressive therapy there are no reliable data on CNI-free protocols. Studies have shown that administration of statins is associated with improved function and survival of lung allografts.
Fuehner
T
T
Abteilung Pneumologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover. fuehner.thomas@mh-hannover.de
Welte
T
T
Simon
A
A
Gottlieb
J
J
D002318:Cardiovascular Diseases / Q000209:etiology*; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006402:Hematologic Diseases / Q000209:etiology*; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology; D016040:Lung Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000209:etiology; D011183:Postoperative Complications / Q000453:epidemiology*