title: Immediate shrinkage of optociliary shunt vessels after fractionated external beam radiation for meningioma of the optic nerve sheath.
abstract: Fractionated stereotactic radiation has become the standard treatment of meningioma of the optic nerve sheath. The mechanism responsible for improvement in visual function is unclear, because neuroimaging after treatment usually shows no discernable change in tumor appearance. We report immediate regression of optociliary shunt vessels in a patient after radiation treatment of an optic nerve sheath meningioma. This observation indicates that radiation treatment can cause rapid reduction of optic nerve compression, even without appreciable reduction in the size of the meningioma.
authors.affiliation: Department of Ophthalmology, University of California, San Francisco, CA 94143-0730, USA
authors.forename: A G
authors.initials: AG
authors.lastname: de Alba Campomanes
authors.forename: D A
authors.initials: DA
authors.lastname: Larson
authors.forename: J C
authors.initials: JC
authors.lastname: Horton
mesh_terms: D002196:Capillaries / Q000473:pathology; D002829:Choroid / Q000098:blood supply* / Q000528:radiation effects*; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000098:blood supply* / Q000532:radiotherapy*; D008579:Meningioma / Q000098:blood supply* / Q000532:radiotherapy*; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000532:radiotherapy*; D009408:Nerve Compression Syndromes / Q000175:diagnosis*; D009898:Optic Disk / Q000098:blood supply / Q000528:radiation effects; D009900:Optic Nerve / Q000098:blood supply* / Q000528:radiation effects*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D019574:Optic Nerve Neoplasms / Q000098:blood supply* / Q000532:radiotherapy*; D012169:Retinal Vein / Q000473:pathology* / Q000528:radiation effects*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014792:Visual Acuity / Q000528:radiation effects; D058609:Visual Field Tests