Cutaneous concentration of lycopene correlates significantly with the roughness of the skin.
Antioxidant substances in the skin are expected to slow down photo ageing. We therefore developed the hypothesis that high levels of antioxidant substances may be correlated to lower levels of skin roughness. By utilizing modern optical non-invasive in vivo methods, the structures of the furrows and wrinkles as well as the concentration of lycopene were analyzed quantitatively on the forehead skin of 20 volunteers aged between 40 and 50 years. In a first step, the age of the volunteers was correlated to their skin roughness. Here, no significant correlation was found. In a second step, a significant correlation was obtained between the skin roughness and the lycopene concentration (R=0.843). These findings indicate that higher levels of antioxidants in the skin effectively lead to lower levels of skin roughness, and therefore support our hypothesis.
Darvin
Maxim
M
Charité-Universitätsmedizin Berlin, Department of Dermatology, Berlin, Germany.
Patzelt
Alexa
A
Gehse
Saskia
S
Schanzer
Sabine
S
Benderoth
Christian
C
Sterry
Wolfram
W
Lademann
Juergen
J
D000328:Adult; D000375:Aging / Q000502:physiology; D000975:Antioxidants / Q000032:analysis*; D002338:Carotenoids / Q000032:analysis*; D005260:Female; D006801:Humans; D008027:Light; D000077276:Lycopene; D008297:Male; D008875:Middle Aged; D012727:Sex Characteristics; D012867:Skin / Q000033:anatomy & histology* / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D013499:Surface Properties
D000975:Antioxidants; D002338:Carotenoids; D000077276:Lycopene