title: Termiticidal activity of diterpenes from the roots of Euphorbia kansui.
abstract: Five ingenane compounds, 1-5, kansuinins A and B, isolated from Euphorbia kansui, and their derivatives 7 and 9 were tested for termiticidal activity against the Japanese termite, Reticulitermes speratus. At 72 hours after treatment, the ingenane compounds 1 to 5 caused 100% mortality in R. speratus at 50, 25 and 12.5 microg/disk, respectively, except for compound 1, which gave a mortality rate of (93.06 +/- 5.56)% at 12.5 microg/disk. At 36, 48 and 60 hours after treatment, compounds 1 to 5 showed more termiticidal activity than kansuinins A and B and their derivatives. The kansuinins showed no or only slight activity against termites in the filter paper bioassay under the conditions tested compared with a solvent control.
authors.affiliation: Graduate School of Natural Science and Technology, Department of Applied Bioscience and Biotechnology, Laboratory of Natural Products Chemistry, Okayama University, Tsushima naka 3-1-1, Okayama 700-8530, Japan.
authors.forename: Jianxiao
authors.initials: J
authors.lastname: Shi
authors.forename: Zhixuan
authors.initials: Z
authors.lastname: Li
authors.forename: Minoru
authors.initials: M
authors.lastname: Izumi
authors.forename: Naomichi
authors.initials: N
authors.lastname: Baba
authors.forename: Shuhei
authors.initials: S
authors.lastname: Nakajima
mesh_terms: D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D028481:Euphorbia / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D020049:Isoptera / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D007306:Insecticides