title: Rapid magnetic resonance elastography of muscle using one-dimensional projection.
abstract: OBJECTIVE
  To demonstrate the feasibility of 1D MR elastography (MRE) to rapidly assess skeletal muscle stiffness in vivo.
  
  
  METHODS
  Shear waves were induced in the vastus medialis muscle (VM) using a pneumatic driver at 90 Hz and 2D MRE data were collected. Spatially selective excitations were used to produce 1D projections of MRE data oriented along the direction of propagating waves in the muscle. Data were collected with the thigh muscles relaxed and contracted at 20% maximum voluntary contraction (MVC) and the knee flexed at 30 degrees .
  
  
  RESULTS
  The muscle stiffness measured at rest and in contraction with 1D MRE was 3.69 +/- 0.80 kPa and 9.52 +/- 2.74 kPa, respectively, and 4.36 +/- 0.98 kPa and 9.22 +/- 1.29 kPa, respectively, with the 2D MRE technique.
  
  
  CONCLUSIONS
  Muscle stiffness measured using 1D MRE was in agreement with 2D MRE while reducing the scan time by a factor of 4.
authors.affiliation: Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
authors.forename: Sabine F
authors.initials: SF
authors.lastname: Bensamoun
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Glaser
authors.forename: Stacie I
authors.initials: SI
authors.lastname: Ringleb
authors.forename: Qingshan
authors.initials: Q
authors.lastname: Chen
authors.forename: Richard L
authors.initials: RL
authors.lastname: Ehman
authors.forename: Kai-Nan
authors.initials: KN
authors.lastname: An
mesh_terms: D000328:Adult; D004548:Elasticity; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007537:Isometric Contraction / Q000502:physiology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D018482:Muscle, Skeletal / Q000033:anatomy & histology* / Q000502:physiology; D013848:Thigh