Of cartridges and columns: new roles for cadherins in visual system development.
In this issue of Neuron, two papers provide new insights into roles for local cadherin-based interactions during axon targeting in the Drosophila visual system. Using high-resolution analyses, Chen and Clandinin identify nonautonomous roles for the atypical cadherin Flamingo during photoreceptor targeting, while Nern et al. demonstrate that local cell type-specific roles for N-cadherin control layer-specific targeting of lamina neurons.
Matthews
Benjamin J
BJ
Department of Neuroscience, Columbia University Medical Center, 630 W. 168(th) Street, P&S 11-511, New York, NY 10032, USA.
Corty
Megan M
MM
Grueber
Wesley B
WB
D000818:Animals; D006801:Humans; D015820:Cadherins / Q000502:physiology; D004330:Drosophila; D017956:Photoreceptor Cells, Invertebrate; D014785:Vision, Ocular / Q000502:physiology; D014795:Visual Pathways / Q000254:growth & development
D015820:Cadherins