title: Signal intensity of the motor cortex on phase-weighted imaging at 3T.
abstract: OBJECTIVE
  It is known that the motor cortex shows hypointensity on T2-weighted images in older patients. The goal of this study was to assess the signal intensity of the motor cortices on the phase-weighted imaging performed with a Windows-based software program that we developed ourselves.
  
  
  METHODS
  All studies were performed at 3T MR imaging. First, the TE for the phase-weighted image was optimized; the best contrast between the motor and other cortices was obtained with a TE of 40 ms. The study population consisted of 45 healthy subjects (23 females, 22 males; mean age, 32.1 years). The signal intensity of the motor cortices was divided into 3 grades by 2 neuroradiologists in comparison with that of the superior frontal cortex (SFC): In grade I, the motor cortex was isointense to the SFC; in grade II, the motor cortex was slightly hypointense to the SFC; and in grade III, the motor cortex was markedly hypointense to the SFC.
  
  
  RESULTS
  The motor cortex was classified as either grade II or III in all subjects older than 20 years of age on the phase-weighted images. Even at 10-19 years of age, the grade II or III appearance was found in 14 (88%) of 16 motor cortices (8 subjects) on the phase-weighted images.
  
  
  CONCLUSIONS
  In adolescents, the motor cortex is hypointense to other cerebral cortices on phase-weighted MR imaging, which probably reflects differences in the concentration of nonheme iron and/or in the tissue architecture.
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan. kakeda@med.uoeh-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Kakeda
authors.forename: Y
authors.initials: Y
authors.lastname: Korogi
authors.forename: K
authors.initials: K
authors.lastname: Kamada
authors.forename: N
authors.initials: N
authors.lastname: Ohnari
authors.forename: J
authors.initials: J
authors.lastname: Moriya
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: M
authors.initials: M
authors.lastname: Kitajima
authors.forename: H
authors.initials: H
authors.lastname: Hasnine
authors.forename: N
authors.initials: N
authors.lastname: Hirata
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology*