The influence of CSF on EEG sensitivity distributions of multilayered head models.
We examined how the cerebrospinal fluid (CSF) affects the distribution of electroencephalogram (EEG) measurement sensitivity. We used concentric spheres and realistic head models to investigate the difference between computed-tomography (CT) and magnetic resonance image (MRI) models that exclude the CSF layer. The cortical EEG sensitivity distributions support these phenomena and show that the CSF layer significantly influences them, thus identifying the importance of including the CSF layer inside the head volume conductor models. The results show that the highly conductive CSF channels the current, thus decreasing the maximum cortical current density relative to models that do not include the CSF. We found that the MRI and CT models yielded HSV results 20% and 45%, respectively, too small when compared with CSF-inclusive models.
Wendel
K
K
Ragnar Granit Institute, Department of Electrical Engineering, Tampere University of Technology, Tampere, Finland. katrina.wendel@tut.fi
Narra
N G
NG
Hannula
M
M
Kauppinen
P
P
Malmivuo
J
J
D016477:Artifacts; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D002555:Cerebrospinal Fluid / Q000502:physiology*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D006257:Head / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity