Interface dermatitis.
Interface dermatitis can be classified based upon the cell type that dominates the infiltrate (ie, neutrophilic, lymphocytic, or lymphohistiocytic) or by the intensity of the interface inflammation. Regarding lymphocytic interface dermatitis, there are 2 broad categories: cell-poor interface dermatitis, when only a sparse infiltrate of inflammatory cells is present along the dermoepidermal junction, or cell rich, which typically occurs as a heavy bandlike infiltrate that obscures the basal layers of the epidermis. In the case of lymphocytic interface dermatitis, the latter is often termed a lichenoid interface dermatitis. This review focuses upon the mononuclear cell-predominant forms of interface dermatitis.
Crowson
A Neil
AN
Department of Dermatology, University of Oklahoma and Regional Medical Laboratories, St John Medical Center, 1923 S Utica Ave, Tulsa, OK 74104, USA. ncrowson@sjmc.org
Magro
Cynthia M
CM
Mihm
Martin C
MC
D001706:Biopsy; D003872:Dermatitis / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D020405:Dermis / Q000473:pathology*; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology*; D006801:Humans; D010336:Pathology / Q000193:education*