title: Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
authors.affiliation: Max-Planck-Institut für molekulare Physiologie, Abt. Physikalische Biochemie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Guo
authors.forename: Yao-Wen
authors.initials: YW
authors.lastname: Wu
authors.forename: Kui-Thong
authors.initials: KT
authors.lastname: Tan
authors.forename: Robin S
authors.initials: RS
authors.lastname: Bon
authors.forename: Ester
authors.initials: E
authors.lastname: Guiu-Rozas
authors.forename: Christine
authors.initials: C
authors.lastname: Delon
authors.forename: T Uyen
authors.initials: TU
authors.lastname: Nguyen
authors.forename: Stefan
authors.initials: S
authors.lastname: Wetzel
authors.forename: Sabine
authors.initials: S
authors.lastname: Arndt
authors.forename: Roger S
authors.initials: RS
authors.lastname: Goody
authors.forename: Wulf
authors.initials: W
authors.lastname: Blankenfeldt
authors.forename: Kirill
authors.initials: K
authors.lastname: Alexandrov
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000235:genetics; D000818:Animals; D019556:COS Cells; D002522:Chlorocebus aethiops; D018360:Crystallography, X-Ray; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D011487:Protein Conformation
chemical_list: D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; C075607:Rab geranylgeranyltransferase