title: Ir-catalyzed regio- and enantioselective Friedel-Crafts-type allylic alkylation of indoles.
abstract: Highly regio- and enantioselective Ir-catalyzed Friedel-Crafts type allylic alkylation of indoles have been realized using [Ir(COD)Cl]2/phosphoramidite ligand 1a, affording the branched products with up to >97/3 branched-linear ratio and 92% ee.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Wen-Bo
authors.initials: WB
authors.lastname: Liu
authors.forename: Hu
authors.initials: H
authors.lastname: He
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Dai
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
mesh_terms: D000478:Alkylation; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007495:Iridium / Q000737:chemistry
chemical_list: D007211:Indoles; D007495:Iridium