title: Activated charcoal and baking soda to reduce odor associated with extensive blistering disorders.
abstract: BACKGROUND
  Skin disease leading to extensive blistering and loss of skin is associated with a characteristic smell. Odor can cause physiologic disturbances such as increase in heart rate and respiratory rate. It can also cause nausea and vomiting and is disturbing to bystanders.
  
  
  OBJECTIVE
  To test odor reducing capability of activated charcoal.
  
  
  METHODS
  In this blinded experimental study we used putrefied amniotic membrane to produce odor and studied the effectiveness of activated charcoal and soda-bi-carbonate to reduce odor.
  
  
  RESULTS
  Statistical analysis with Kruskal Wall's Chi Square Test and Man Whitney U test showed significant reduction of odor using activated charcoal by itself or along with soda-bi-carbonate.
  
  
  CONCLUSIONS
  We recommend the usage of activated charcoal with/without soda bicarbonate as an inexpensive practical measure to reduce foul odor associated with extensive skin loss.
authors.affiliation: Department of Dermatology, PSG Hospitals, Peelamedu, Coimbatore, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Chakravarthi
authors.forename: C R
authors.initials: CR
authors.lastname: Srinivas
authors.forename: Anil C
authors.initials: AC
authors.lastname: Mathew
mesh_terms: D000650:Amnion / Q000187:drug effects; D001768:Blister / Q000150:complications* / Q000188:drug therapy*; D002606:Charcoal / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D009812:Odorants / Q000517:prevention & control*; D017693:Sodium Bicarbonate / Q000008:administration & dosage*
chemical_list: D002606:Charcoal; D017693:Sodium Bicarbonate