title: Dragonamides C and D, linear lipopeptides from the marine cyanobacterium brown Lyngbya polychroa.
abstract: Two new linear lipopeptides, 1 and 2, and a known compound, curacin D, have been isolated from a marine cyanobacterium, brown Lyngbya polychroa, collected from Hollywood Beach, Fort Lauderdale, Florida. Their planar structures were elucidated by 1D and 2D NMR techniques, and absolute configurations were assigned using chiral HPLC. The new compounds were assigned the trivial names dragonamide C (1) and dragonamide D (2), as their peptide moiety is related to previously reported dragonamides A and B.
authors.affiliation: Smithsonian Marine Station, Fort Pierce, FL 34949, USA.
authors.forename: Sarath P
authors.initials: SP
authors.lastname: Gunasekera
authors.forename: Cliff
authors.initials: C
authors.lastname: Ross
authors.forename: Valerie J
authors.initials: VJ
authors.lastname: Paul
authors.forename: Susan
authors.initials: S
authors.lastname: Matthew
authors.forename: Hendrik
authors.initials: H
authors.lastname: Luesch
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000458:Cyanobacteria / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D005431:Florida; D006801:Humans; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009842:Oligopeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D009842:Oligopeptides; C530239:dragonamide C; C530238:dragonamide D