title: Von Recklinghausen's disease--elements of clinical practice.
abstract: Neurofibromatosis is a condition described for the first time by Von Recklingahausen in 1882. This disease is one of the most common genetic disorders and is characterized by multiple tumors of the central and peripheral nervous system, brown macules on the skin, bone deformities, and by vascular and visceral disorders. Despite extensive basic science research, the diagnosis is still based largely on clinical criteria, which often present gradually during childhood.
authors.affiliation: Pediatric Orthopedic Clinic, Maria Sklodowska Curie Emergency Hospital for Children, Bucharest, Romania. mscburnei@yahoo.com
authors.forename: G
authors.initials: G
authors.lastname: Burnei
authors.forename: C
authors.initials: C
authors.lastname: Vlad
authors.forename: Ileana
authors.initials: I
authors.lastname: Georgescu
authors.forename: S
authors.initials: S
authors.lastname: Gavriliu
authors.forename: Daniela
authors.initials: D
authors.lastname: Dan
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Vlad
mesh_terms: D006801:Humans; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy