title: Chronic antithrombotic therapy in post-myocardial infarction patients.
abstract: Because 1.1 million myocardial infarctions occur in the United States alone each year, and 450,000 of them are recurrent infarctions, which carry an inherently greater risk of death and disability than first events, the importance of secondary prevention strategies that can be implemented widely is unparalleled in health care. Antithrombotic therapies, both antiplatelet and anticoagulant, have become the mainstays of these strategies. This article covers the use of chronic antiplatelet and anticoagulation agents after myocardial infarction. It does not include the management of these patients in the acute phase.
authors.affiliation: Lankenau Institute for Medical Research, Clinical Research Center, Suite G-36, 100 Lancaster Avenue, Wynnewood, PA 19096-3425, USA.
authors.forename: Rangadham
authors.initials: R
authors.lastname: Nagarakanti
authors.forename: Sandeep
authors.initials: S
authors.lastname: Sodhi
authors.forename: Robert
authors.initials: R
authors.lastname: Lee
authors.forename: Michael
authors.initials: M
authors.lastname: Ezekowitz
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage; D001384:Azetidines / Q000008:administration & dosage; D001596:Benzylamines / Q000008:administration & dosage; D000077144:Clopidogrel; D006801:Humans; D009203:Myocardial Infarction / Q000453:epidemiology*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000453:epidemiology*; D015539:Platelet Activation / Q000502:physiology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012307:Risk Factors; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy* / Q000517:prevention & control; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D014812:Vitamin K / Q000037:antagonists & inhibitors; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D001384:Azetidines; D001596:Benzylamines; D010975:Platelet Aggregation Inhibitors; D014812:Vitamin K; C426686:ximelagatran; D014859:Warfarin; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin