title: [Staphylococcus aureus bacteremia and endocarditis].
abstract: The prevalence of Stapylococcus bacteriaemia is increasing worldwide, because of the increasing use of invasive procedures leading to nosocomial infections, but also of a changing way of life (increasing fashion for tattoos or piercing, use of intravenous drugs). Infective endocarditis develops in 10-30% of the cases of staphylococcus bacteriaemia. Staphylococcus aureus endocarditis must be suspected when it develops in the year following heart surgery or implantation of permanent devices. In drug users, it usually involves the tricuspid valve. According to the resistance of the germ to meticillin, antibiotic therapy uses a combination of intravenous penicillin or glycopeptide and an aminoside. Other antibiotics such as fosfomycin, rifampicin, fusidic acid, or clindamycin can be used when aminosides are contra-indicated. The role of newer antibiotic agents, such as daptomycin or linezolide, remains to be established.
authors.affiliation: Service de maladies infectieuses et tropicales, CHU de Nancy, 54511 Vandoeuvre-les-Nancy cedex, France.
authors.forename: J-C
authors.initials: JC
authors.lastname: Lagier
authors.forename: L
authors.initials: L
authors.lastname: Letranchant
authors.forename: C
authors.initials: C
authors.lastname: Selton-Suty
authors.forename: J
authors.initials: J
authors.lastname: Nloga
authors.forename: N
authors.initials: N
authors.lastname: Aissa
authors.forename: C
authors.initials: C
authors.lastname: Alauzet
authors.forename: J-P
authors.initials: JP
authors.lastname: Carteaux
authors.forename: T
authors.initials: T
authors.lastname: May
authors.forename: T
authors.initials: T
authors.lastname: Doco-Lecompte
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000628:therapy*; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents