title: RhoB can adopt a Mg2+ free conformation prior to GEF binding.
authors.affiliation: Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Old Road Campus, off Roosevelt Drive, Headington OX3 7DQ, United Kingdom.
authors.forename: Meera
authors.initials: M
authors.lastname: Soundararajan
authors.forename: Andrew
authors.initials: A
authors.lastname: Turnbull
authors.forename: Oleg
authors.initials: O
authors.lastname: Fedorov
authors.forename: Catrine
authors.initials: C
authors.lastname: Johansson
authors.forename: Declan A
authors.initials: DA
authors.lastname: Doyle
mesh_terms: D004795:Enzyme Stability / Q000187:drug effects; D020662:Guanine Nucleotide Exchange Factors / Q000378:metabolism*; D006868:Hydrolysis / Q000187:drug effects; D008274:Magnesium / Q000378:metabolism* / Q000494:pharmacology; D008958:Models, Molecular; D011485:Protein Binding / Q000187:drug effects; D017433:Protein Structure, Secondary; D020742:rhoA GTP-Binding Protein / Q000737:chemistry; D020743:rhoB GTP-Binding Protein / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D020662:Guanine Nucleotide Exchange Factors; D020742:rhoA GTP-Binding Protein; D020743:rhoB GTP-Binding Protein; D008274:Magnesium