[Gastric plasmacytoma as an uncommon cause of upper gastrointestinal bleeding].
Gastric plasmacytoma is an infrequent form of presentation of monoclonal gammopathy that, if ulcerated, can cause upper gastrointestinal bleeding. This entity is usually localized but may progress to multiple myeloma or other forms of monoclonal gammopathy. Differential diagnosis should be performed with other monoclonal gammopathies, based on laboratory and histological criteria, as well as with other gastric tumors such as adenocarcinoma, gastrointestinal stromal tumors, neuroendocrine tumors and lymphomas. Differential diagnosis can be based on radiological and endoscopic characteristics, although definitive diagnosis will undoubtedly be based on histological study and immunohistochemical techniques. We describe the case of a male patient who underwent investigations for upper gastrointestinal bleeding and iron deficiency anemia. The final diagnosis was multiple myeloma associated with gastric plasmacytoma.
Vicuña Arregui
Miren
M
Servicio de Aparato Digestivo, Hospital de Navarra, Pamplona, Navarra, Spain. mirva77@hotmail.com
Borobio Aguilar
Erika
E
Vila Costas
Juan José
JJ
Viguria Alegría
M Cruz
MC
Arrechea Irigoyen
Miren
M
Borda Celaya
Fernando
F
Martínez-Peñuela Vinseda
José María
JM
D000230:Adenocarcinoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis; D008297:Male; D008551:Melena / Q000209:etiology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis; D009378:Neoplasms, Multiple Primary; D010954:Plasmacytoma / Q000150:complications* / Q000175:diagnosis; D012004:Rectal Neoplasms; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis; D013276:Stomach Ulcer / Q000209:etiology