Chronic antithrombotic therapy in post-myocardial infarction patients.
Because 1.1 million myocardial infarctions occur in the United States alone each year, and 450,000 of them are recurrent infarctions, which carry an inherently greater risk of death and disability than first events, the importance of secondary prevention strategies that can be implemented widely is unparalleled in health care. Antithrombotic therapies, both antiplatelet and anticoagulant, have become the mainstays of these strategies. This article covers the use of chronic antiplatelet and anticoagulation agents after myocardial infarction. It does not include the management of these patients in the acute phase.
Nagarakanti
Rangadham
R
Lankenau Institute for Medical Research, Clinical Research Center, Suite G-36, 100 Lancaster Avenue, Wynnewood, PA 19096-3425, USA.
Sodhi
Sandeep
S
Lee
Robert
R
Ezekowitz
Michael
M
D000925:Anticoagulants / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage; D001384:Azetidines / Q000008:administration & dosage; D001596:Benzylamines / Q000008:administration & dosage; D000077144:Clopidogrel; D006801:Humans; D009203:Myocardial Infarction / Q000453:epidemiology*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000453:epidemiology*; D015539:Platelet Activation / Q000502:physiology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012307:Risk Factors; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy* / Q000517:prevention & control; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D014812:Vitamin K / Q000037:antagonists & inhibitors; D014859:Warfarin / Q000008:administration & dosage
D000925:Anticoagulants; D001384:Azetidines; D001596:Benzylamines; D010975:Platelet Aggregation Inhibitors; D014812:Vitamin K; C426686:ximelagatran; D014859:Warfarin; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin