Endoscopic mucosal resection in the upper gastrointestinal tract.
Endoscopic mucosal resection (EMR) is a technique used to locally excise lesions confined to the mucosa. Its main role is the treatment of advanced dysplasia and early gastrointestinal cancers. EMR was originally described as a therapy for early gastric cancer. Recently its use has expanded as a therapeutic option for ampullary masses, colorectal cancer, and large colorectal polyps. In the Western world, the predominant indication for EMR in the upper gastrointestinal tract is the staging and treatment of advance dysplasia and early neoplasia in Barrett's esophagus. This review will describe the basis, indications, techniques, and complications of EMR, and its role in the management of Barrett's esophagus.
Ahmadi
Anis
A
Division Gastroenterology Hepatology and Nutrition, University of Florida, Gainesville, Florida 32610, United States.
Draganov
Peter
P
D000818:Animals; D001471:Barrett Esophagus / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D004724:Endoscopy / Q000009:adverse effects / Q000379:methods*; D005762:Gastroenterology / Q000379:methods; D005770:Gastrointestinal Neoplasms / Q000473:pathology / Q000601:surgery; D041981:Gastrointestinal Tract / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D011230:Precancerous Conditions