Chromosome segregation: organizing overlap at the midzone.
Sets of overlapping microtubules support the segregation of chromosomes by linking the poles of mitotic spindles. Recent work examines the effect of putting these linkages under pressure by the activation of dicentric chromosomes and sheds new light on the structural role of several well-known spindle midzone proteins.
Janson
Marcel E
ME
Laboratory of Plant Cell Biology, Wageningen University, Wageningen, The Netherlands.
Tran
Phong T
PT
D020090:Chromosome Segregation / Q000502:physiology*; D015825:Chromosomes, Fungal / Q000502:physiology; D008870:Microtubules / Q000502:physiology; D012441:Saccharomyces cerevisiae; D008941:Spindle Apparatus / Q000502:physiology*