title: [Tracheal intubation without muscle relaxant--the impact of different sufentanil doses on the quality of intubating conditions: a prospective study].
abstract: BACKGROUND
  Following opioid and intravenous anaesthetic, tracheal intubation may be accomplished without any muscle relaxant. In this study, we evaluated the dose requirements for sufentanil with propofol without muscle relaxant administration to obtain clinically acceptable intubation conditions and cardiovascular responses.
  
  
  RESULTS
  After midazolam (0.05 mg x kg(-1)), 90 patients were randomized into three equal groups, each receiving sufentanil 0.2 (SUF-0.2), 0.3 (SUF-0.3) or 0.4 (SUF-0.4) microg x kg(-1), respectively. Following induction of anaesthesia with propofol (2 mg x kg(-1)), the quality of tracheal intubation was assessed as excellent or good (clinically acceptable) and poor. Excellent intubation conditions were observed in 28%, 41% and 54% of patients in groups SUF-0.2, SUF-0.3 and SUF-0.4, respectively, while poor conditions were present in 31% (SUF-0.2; p = 0.041 vs. SUF-0.3, p = 0.006 vs SUF-0.4), 7% (SUF-0.3) and 3% (SUF-0.4). Patients with induction-related hypotension were older than those without (60 +/- 15 vs. 52 +/- 17 yr, p = 0.013).
  
  
  CONCLUSIONS
  Sufentanil (0.3-0.4 microg x kg(-1)) in combination with propofol (2 mg.kg(-1)) provided clinically acceptable intubating conditions in 93-97% patients.
authors.affiliation: Klinika anesteziologie a resuscitace LF UP a FN, Olomouc. milan.adamus@seznam.cz
authors.forename: M
authors.initials: M
authors.lastname: Adamus
authors.forename: J
authors.initials: J
authors.lastname: Koutná
authors.forename: T
authors.initials: T
authors.lastname: Gabrhelík
authors.forename: J
authors.initials: J
authors.lastname: Zapletalová
mesh_terms: D000768:Anesthesia, General; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage; D015742:Propofol / Q000008:administration & dosage; D017409:Sufentanil / Q000008:administration & dosage*
chemical_list: D018686:Anesthetics, Intravenous; D009466:Neuromuscular Blocking Agents; D017409:Sufentanil; D015742:Propofol