Comparison of nasal swabs with nose blowing for community-based pneumococcal surveillance of healthy children.
The nasopharynx (NP) is the preferred site for detection of Streptococcus pneumoniae in young children, but NP sampling is not well tolerated. We compared nose blowing with paired nasal swabs. The sensitivity of nose blowing was 46% (95% confidence interval [CI] 38 to 56%), which increased to 94% (95% CI, 85 to 98%) for children with visible secretions.
Leach
Amanda Jane
AJ
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia. amanda.leach@menzies.edu.au
Stubbs
Elizabeth
E
Hare
Kim
K
Beissbarth
Jemima
J
Morris
Peter Stanley
PS
D001315:Australia; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D002648:Child; D002656:Child Day Care Centers; D002675:Child, Preschool; D006801:Humans; D009305:Nasopharynx / Q000378:metabolism* / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000382:microbiology; D011159:Population Surveillance; D012424:Rural Population; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*; D014505:Urban Population