title: Incidental prostate cancer detected by cystoprostatectomy in Korean men.
abstract: OBJECTIVE
  To determine the incidence and characteristics of incidental prostate cancer diagnosed by cystoprostatectomy (CPT) in Korean men.
  
  
  METHODS
  Thirty-six consecutive male patients scheduled to undergo CPT were prospectively enrolled. The CPT specimens were examined and the clinicopathologic characteristics of incidental cancers compared with those of T1c prostate cancers that had undergone radical prostatectomy. Complete transverse sections of the prostate were taken from the apex to the base at 4-mm intervals.
  
  
  RESULTS
  Of the 36 CPT patients, 18 (50%) had incidental prostate cancer. Most of the incidental tumors were confined to the prostate gland, except in 1 patient. Tumor involvement at the prostate apex was found in 3 patients (16.7%), and Gleason scores in 3 cases were 7 to 10. Median tumor volume was 0.08 cm(3) (range, 0.01 to 20.51 cm(3)), and a tumor volume of more than 0.5 cm(3) was identified in 5 patients. Of these incidental prostate cancers, 38.9% (19.4% of all CPT patients) were clinically significant. As compared with the 38 T1c prostate cancer patients, incidental prostate cancer patients were older, had a lower prostate-specific antigen level, a lower grade, smaller tumor volume, and were less likely to have multiple tumors. However, no significant differences were observed between these two groups with respect to apical tumor involvement or tumor confinement to the prostate (P >0.05 for each).
  
  
  CONCLUSIONS
  Incidental prostate cancers were diagnosed in 50% of CPT specimens, and 19.4% of these were clinically significant.
authors.affiliation: Urologic Oncology Clinic and Department of Pathology, National Cancer Center, Goyang, Korea.
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Joung
authors.forename: Seung Ok
authors.initials: SO
authors.lastname: Yang
authors.forename: Ho Kyung
authors.initials: HK
authors.lastname: Seo
authors.forename: Taek Sang
authors.initials: TS
authors.lastname: Kim
authors.forename: Kyung Seok
authors.initials: KS
authors.lastname: Han
authors.forename: Jinsoo
authors.initials: J
authors.lastname: Chung
authors.forename: Weon Seo
authors.initials: WS
authors.lastname: Park
authors.forename: In Gab
authors.initials: IG
authors.lastname: Jeong
authors.forename: Kang Hyun
authors.initials: KH
authors.lastname: Lee
mesh_terms: D000368:Aged; D015653:Cystectomy; D006801:Humans; D015994:Incidence; D033162:Incidental Findings; D007723:Korea; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology