title: Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase.
abstract: Research on the enzyme 11beta-hydroxysteroid dehydrogenase, initially performed on congenital deficiency of the enzyme, and later work on deficiency of the enzyme after licorice and carbenoxolone administration, led to the hypothesis that 11beta-hydroxysteroid dehydrogenase conferred specificity on the mineralocorticoid receptor.
authors.affiliation: Department of Medicine, Queen Elizabeth Hospital, Birmingham, UK.
authors.forename: P M
authors.initials: PM
authors.lastname: Steward
authors.forename: C R
authors.initials: CR
authors.lastname: Edwards