title: Parathyroid hormone-like peptide: molecular characterization and biological properties.
abstract: Parathyroid hormone-like peptide (PLP) is a newly discovered novel peptide that interacts with renal and osseous parathyroid hormone (PTH) receptors through its amino-terminal sequence, which is homologous with PTH. Human PLP is the product of a complex single-copy gene, existing in several isoforms which result from alternative exon usage. The peptide was implicated as a causal agent in the hypercalcemia associated with a variety of malignancies, but it may also modulate calcium homeostasis in some normal physiological states and mediate cellular growth or differentiation.
authors.affiliation: Departments of Physiology and Medicine, McGill University, Montreal, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Goltzman
authors.forename: G N
authors.initials: GN
authors.lastname: Hendy
authors.forename: D
authors.initials: D
authors.lastname: Banville