Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
Guo
Zhong
Z
Max-Planck-Institut für molekulare Physiologie, Abt. Physikalische Biochemie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Wu
Yao-Wen
YW
Tan
Kui-Thong
KT
Bon
Robin S
RS
Guiu-Rozas
Ester
E
Delon
Christine
C
Nguyen
T Uyen
TU
Wetzel
Stefan
S
Arndt
Sabine
S
Goody
Roger S
RS
Blankenfeldt
Wulf
W
Alexandrov
Kirill
K
Waldmann
Herbert
H
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000235:genetics; D000818:Animals; D019556:COS Cells; D002522:Chlorocebus aethiops; D018360:Crystallography, X-Ray; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D011487:Protein Conformation
D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; C075607:Rab geranylgeranyltransferase