title: Immunohistochemical distribution of viral antigens in pigs naturally infected with porcine teschovirus.
abstract: A distribution of porcine teschovirus (PTV) antigens in pigs naturally infected with PTV is presented using the method of immunohistochemical examination. In the nervous system, PTV antigens were found in the cytoplasm of neuronal cells and glial cells distributed in the spinal ventral horn and brain stem, and also in the cytoplasm of ganglion cells in the spinal ganglion. No antigens were seen in the cerebral hemisphere. In the nervous system, the distribution of PTV antigens was consistent with lesions characteristic of nonsuppurative encephalomyelitis. In the other examined organ, PTV antigens were observed in bronchiolar epithelial cells in the lung, hepatocytes in the liver, epithelial cells in the tonsils and the myenteric nerve plexus in the small and large intestine.
authors.affiliation: National Institute of Animal Health, Tsukuba, Ibaraki, Japan. oomae@affrc.go.jp
authors.forename: Manabu
authors.initials: M
authors.lastname: Yamada
authors.forename: Rie
authors.initials: R
authors.lastname: Kozakura
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kaku
authors.forename: Kikuyasu
authors.initials: K
authors.lastname: Nakamura
authors.forename: Yu
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Masaaki
authors.initials: M
authors.lastname: Yoshii
authors.forename: Ayako
authors.initials: A
authors.lastname: Miyazaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsunemitsu
authors.forename: Minoru
authors.initials: M
authors.lastname: Narita
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification*; D004386:Duodenum / Q000821:virology; D007150:Immunohistochemistry / Q000662:veterinary; D008168:Lung / Q000821:virology; D008526:Medulla Oblongata / Q000821:virology; D010850:Picornaviridae Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D013116:Spinal Cord / Q000821:virology; D034421:Sus scrofa; D013553:Swine Diseases / Q000473:pathology* / Q000821:virology*; D052700:Teschovirus
chemical_list: D000956:Antigens, Viral