Efficient intermolecular iron-catalyzed amidation of C-H bonds in the presence of N-bromosuccinimide.
We have developed an efficient, inexpensive, and air-stable catalyst/oxidant (FeCl2/NBS) system that could efficiently promote amidation of benzylic sp3 C-H bonds in ethyl acetate under mild conditions.
Wang
Zhe
Z
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, PR China.
Zhang
Yongming
Y
Fu
Hua
H
Jiang
Yuyang
Y
Zhao
Yufen
Y
D000085:Acetates / Q000737:chemistry*; D001974:Bromosuccinimide / Q000737:chemistry*; D002384:Catalysis; D007501:Iron / Q000737:chemistry*
D000085:Acetates; C007650:ethyl acetate; D007501:Iron; D001974:Bromosuccinimide