title: Two new antibacterial norabietane diterpenoids from cyanobacteria, Microcoleous lacustris.
abstract: Two abietane diterpenes were isolated from cyanobacteria Microcoleous lacustris, 20-nor-3alpha-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3alpha-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. These compounds were assayed against Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Vibrio cholerae, Bacillus subtilis, Bacillus cereus, Escherichia coli, and Klebsiella pneumoniae. Both compounds showed activity against S. aureus, S. epidermidis, S. typhi, and V. cholerae, but not against the other bacteria.
authors.affiliation: Natural Products Research Laboratory, Industrias Extractivas (ESIQUIE)-IPN, Punto Fijo 16, Col. Torres Lindavista, C.P. 07708, Mexico DF, Mexico. rmpg@prodigy.net.mx
authors.forename: Rosa Martha
authors.initials: RM
authors.lastname: Pérez Gutiérrez
authors.forename: Amalia
authors.initials: A
authors.lastname: Martínez Flores
authors.forename: Rosario
authors.initials: R
authors.lastname: Vargas Solís
authors.forename: Javier
authors.initials: J
authors.lastname: Carmona Jimenez
mesh_terms: D045784:Abietanes / Q000302:isolation & purification / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D000458:Cyanobacteria / Q000737:chemistry*; D008826:Microbial Sensitivity Tests
chemical_list: C529866:20-nor-3alpha-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene; C529865:20-nor-3alpha-acetoxyabieta-5,7,9,11,13-pentaene; D045784:Abietanes; D000900:Anti-Bacterial Agents