Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters Part I. Regioselective hydrogenation of stigmasterol: an easy access to oxyphytosterols.
The synthesis of several oxyphytosterols is described starting from stigmasterol, the key step being the regioselective hydrogenation of the 22-23 double bond of the latter.
Geoffroy
Philippe
P
Institut de Chimie, Université Louis Pasteur, UMR CNRS/ULP 7177-Laboratoire de Chimie Organique Synthétique-1, Strasbourg-Cedex, France.
Julien-David
Diane
D
Marchioni
Eric
E
Raul
Francis
F
Aoudé-Werner
Dalal
D
Miesch
Michel
M
D015195:Drug Design; D006865:Hydrogenation; D010840:Phytosterols / Q000138:chemical synthesis* / Q000737:chemistry; D013265:Stigmasterol / Q000138:chemical synthesis* / Q000737:chemistry
D010840:Phytosterols; D013265:Stigmasterol