A new Erythrina alkaloid from Erythrina herbacea.
A new Erythrina alkaloid, 10-hydroxy-11-oxoerysotrine (1), has been isolated from the flowers of Erythrina herbacea together with five known compounds: erytharbine (2), 10,11-dioxoerysotrine (3), erythrartine (4), erysotramidine (5) and erysotrine-N-oxide (6). The structure of the new compound was elucidated on the basis of its spectral data, including 2-D NMR and mass (MS) spectra. The new compound is a rare C-10 oxygenated Erythrina alkaloid. The antioxidant activities of the isolated compounds 1-6 were evaluated by scavenging with peroxynitrite.
Tanaka
Hitoshi
H
Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya, 468-8503, Japan. hitoshi@ccmfs.meijo-u.ac.jp
Hattori
Hisanori
H
Tanaka
Toshihiro
T
Sakai
Eiji
E
Tanaka
Nobuyuki
N
Kulkarni
Aditya
A
Etoh
Hideo
H
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds; D002850:Chromatography, Gel; D004895:Erythrina / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D030421:Peroxynitrous Acid / Q000737:chemistry; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
C529811:10-hydroxy-11-oxoerysotrine; D000470:Alkaloids; D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006576:Heterocyclic Compounds, 4 or More Rings; D010851:Picrates; D010936:Plant Extracts; C492626:erysotramidine; D030421:Peroxynitrous Acid; C004931:1,1-diphenyl-2-picrylhydrazyl