title: Assessment of human health risk from organochlorine pesticide residues in Cidade dos Meninos, Duque de Caxias, Rio de Janeiro, Brazil.
abstract: This article presents the results of a heath risk assessment in Cidade dos Meninos, an area contaminated with organochlorine pesticide residues located in the county (municipality) of Duque de Caxias, Rio de Janeiro State, Brazil. The Agency for Toxic Substances and Disease Registry (ATSDR) risk assessment methodology was applied. The following organochlorine compounds exceeded the established limits and were considered target pollutants: HCH and its isomers (in eggs, milk, and soil); DDT and its metabolites; trichlorobenzenes; trichlorophenols; dioxins and furans (eggs and soil). For all the substances studied (with the exception of trichlorophenols), the estimated doses exceeded the minimum risk levels for chronically exposed children and adults. According to the ATSDR classification, the area was considered an "urgent public health hazard" because of its high and serious exposure to substances that are dangerous to human health.
authors.affiliation: Núcleo de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. carmenfroes@nesc.ufrj.br
authors.forename: Carmen Ildes R Fróes
authors.initials: CI
authors.lastname: Asmus
authors.forename: Herling Gregorio Aguilar
authors.initials: HG
authors.lastname: Alonzo
authors.forename: Marisa
authors.initials: M
authors.lastname: Palácios
authors.forename: Alexandre Pessoa da
authors.initials: AP
authors.lastname: Silva
authors.forename: Maria Isabel de
authors.initials: MI
authors.lastname: Freitas Filhote
authors.forename: Daniela
authors.initials: D
authors.lastname: Buosi
authors.forename: Volney de Magalhães
authors.initials: Vde M
authors.lastname: Câmara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil; D002274:Carcinogens, Environmental / Q000009:adverse effects* / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000633:toxicity*; D007223:Infant; D008297:Male; D008875:Middle Aged; D010573:Pesticide Residues / Q000032:analysis / Q000633:toxicity*; D018570:Risk Assessment; D012987:Soil / Q000032:analysis*
chemical_list: D002274:Carcinogens, Environmental; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D012987:Soil