Peritumoral edema and prognosis in intracranial meningioma surgery.
Peritumoral brain edema (PTBE) is often associated with meningiomas. PTBE is probably implicated in the complications occurring in intracranial meningiomas. The goal of this study was to determine the exact implication of PTBE in prognosis. Thirty consecutive patients who underwent surgery for intracranial meningiomas were investigated over a 1-year period. We focused on the clinical and radiological status before and after surgery, and postoperative complications. Multiple regression analysis revealed a close correlation (p<0.05) between PTBE and symptoms, type of arterial supply, difficulty of surgical removal, and postoperative complications. PTBE is likely implicated in the morbidity of intracranial meningiomas. We suggest predictive factors for difficult surgical resection, and emphasise the importance of medical preoperative management and post-operative follow-up.
Vignes
J R
JR
Department of Neurosurgery A, University Hospital of Bordeaux, University of Bordeaux 2, Bordeaux, France. jean-rodolphe.vignes@chu-bordeaux.fr
Sesay
M
M
Rezajooi
K
K
Gimbert
E
E
Liguoro
D
D
D000328:Adult; D000368:Aged; D001812:Blood-Brain Barrier / Q000503:physiopathology; D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D007902:Length of Stay; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014882:Water-Electrolyte Balance