Recent considerations in the treatment of hypothyroidism.
Thyroid hormone deficiency has been recognized and treated with various forms of thyroid hormone replacement over the last century. Since the 1950s, synthetic L-thyroxine has been the therapy of choice. However, there is now recognition that the currently available regimens for the treatment of hypothyroidism may not adequately address the needs of all patients. This review summarizes recent considerations in the field of thyroidology to address the potential for improvement in the treatment of patients. The goal of these improvements should be to achieve both clinical and chemical euthyroidism.
Danzi
Sara
S
North Shore University Hospital, Department of Medicine and the Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA.
Klein
Irwin
I
D005067:Euthyroid Sick Syndromes / Q000097:blood / Q000188:drug therapy*; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000188:drug therapy*; D012720:Severity of Illness Index; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use*; D016896:Treatment Outcome; D014284:Triiodothyronine / Q000031:analogs & derivatives / Q000097:blood / Q000627:therapeutic use*
D014284:Triiodothyronine; D013974:Thyroxine