title: [Recessive lethal mutation in X-cromosome locus 6D1-7A2 in heterozygote leads to life span increasing in Drosophila melanogaster].
abstract: The results of demographic analysis of survival of different Drosophila lines have shown that recessive lethal mutation located in X-chromosome locus 6D1-7A2, as compared with wild type strain, in heterozygote leads to aging speed deceleration (decreasing of mortality trajectory slope), median (20%) and maximal (15-20%) life span increasing. Further investigations (complementation analysis with duplicated loci) will enable to discover, whether it is unknown life span gene.
authors.forename: A A
authors.initials: AA
authors.lastname: Moskalev
authors.forename: E N
authors.initials: EN
authors.lastname: Pliusnina
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics / Q000254:growth & development; D005260:Female; D017344:Genes, Insect; D005804:Genes, Lethal; D005808:Genes, Recessive; D006579:Heterozygote; D008136:Longevity / Q000235:genetics*; D009154:Mutation; D014960:X Chromosome / Q000235:genetics*