Effect of vasectomy via inguinal canal on spermatogenesis in rabbits.
OBJECTIVE
To determine whether vasectomy away from the epididymal tail (via the inguinal canal) in rabbits can reduce the early postoperative effects on spermatogenesis.


METHODS
Twenty-nine normal male Japanese white rabbits (aged 4-6 months) were subjected to unilateral close-ended (conventional) or open-ended (the cut end of the juxta-epididymal vas deferens not ligated) vasectomy via the inguinal canal. Ten days and 3 months after operation, testes, epididymides and vasa deferentia were removed and methacrylate resin-embedded sections prepared. The histology of the testis, epididymis and vas deferens was examined under light microscope, and the volume and diameter of the seminiferous tubules were quantitatively studied using stereological methods.


RESULTS
Neither of the methods of vasectomy led to apparent damage to spermatogenesis on the vasectomized side in comparison with the contralateral sham-operated side, but the juxta-epididymal vas deferens on the vasectomized side was highly distended and contained numerous sperm 3 months after operation.


CONCLUSIONS
Vasectomy away from the cauda epididymis has no significant early postoperative effects on spermatogenesis in rabbits.
Peng
Bin
B
Morphometric Research Laboratory, North Sichuan Medical College, 234 Fujiang Road, and School Hospital of North Sichuan Medical College, Nanchong 637007, China.
Wang
Ya-Ping
YP
Shang
Yi
Y
Guo
Yang
Y
Yang
Zheng-Wei
ZW
D000818:Animals; D008297:Male; D011817:Rabbits; D013091:Spermatogenesis; D014659:Vasectomy / Q000379:methods*