Aspergillus fumigatus endocarditis in a pediatric liver transplant recipient: favorable outcome without cardiac surgery.
Transplant recipients are very susceptible to invasive aspergillosis, which increases mortality rate. Disseminated aspergillosis in the liver transplant recipient can affect virtually any organ and endocarditis is often lethal despite cardiac surgery and antifungal therapy. We report the case of a eight-month-old girl who presented with Aspergillus fumigatus endocarditis 18 days after liver transplantation that was successfully treated by a combination of antifungal drugs associated to a low dosage of immunosuppressive therapy.
Mourier
Olivia
O
Hepatology and National Reference Centre for Biliary Atresia, Bicêtre Hospital University of Paris, France.
Durand
Philippe
P
Lambert
Virginie
V
Bretagne
Stéphane
S
Maurage
Chantal
C
Branchereau
Sophie
S
Bernard
Olivier
O
Jacquemin
Emmanuel
E
D000284:Administration, Oral; D001228:Aspergillosis / Q000209:etiology* / Q000382:microbiology; D001232:Aspergillus fumigatus / Q000378:metabolism*; D015150:Echocardiography, Doppler / Q000379:methods; D004696:Endocarditis / Q000209:etiology* / Q000382:microbiology*; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications; D013997:Time Factors; D016896:Treatment Outcome
D007166:Immunosuppressive Agents