title: [Changes of the serotonergic system activity in fish tissues during an increase of water salinity].
abstract: Changes of environment parameters produce essential effects on the serotonergic system activity in the body tissues. This paper describes study of the serotonergic system activity in various tissues of half-migratory fish - the Caspian roach Rutilus rutilus caspicus and the bream Abramis brama orientalis - caught in the fresh and brackish water. Using the method of indirect solid-phase ELISA test, the serotonergic system activity was assessed by determining in the studied fish tissues of the amount of serotonin-modulating anticonsolidation protein (SMAP) that is in the linear correlation with serotonin level. A significant change of the SMAP level in the Caspian roach and bream brain was found under effect on increased water salinity. Analysis of the SMAP amount in the bream liver did not reveal any differences in the animals caught in the brackish and fresh water. At the same time, in the bream gill there was a small rise of the SMAP content in the fish caught in the brackish water. The revealed in this experiment elevation of the SMAP amount in the Caspian roach and bream brain reflecting a corresponding increase of the serotonergic system activity indicates involvement of adaptive readjustments in the animal body.
authors.forename: N Dzh
authors.initials: ND
authors.lastname: Mustafaev
authors.forename: A A
authors.initials: AA
authors.lastname: Mekhtiev
mesh_terms: D000220:Adaptation, Biological / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000378:metabolism; D003530:Cyprinidae / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D054712:Salinity; D012701:Serotonin / Q000378:metabolism*
chemical_list: D009419:Nerve Tissue Proteins; D012701:Serotonin