[Leukocyte-endothelium interaction in pial arterioles and venules following cerebral ischaemia of rat].
With the help of contact optic system leukocytes interaction to endothelium of both pial arterioles and venules was investigated during cerebral ischaemia caused by bilateral occlusion of carotids, in vivo. The data received on 40 arterioles and 30 venules (diameter under 40 microns) of pia matter of Wistar rats (n = 7) under ischemic conditions following 5 hours up to respiratory arrest were analyzed. In this experiment, significant differences in adhesiveness of leukocytes to endothelium of arterial and venous microvessels during hypoxia development were shown.
Mel'nikova
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D000818:Animals; D001160:Arterioles / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000098:blood supply* / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D002545:Brain Ischemia / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D002448:Cell Adhesion; D004730:Endothelium, Vascular / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D007962:Leukocytes / Q000378:metabolism* / Q000473:pathology; D008297:Male; D051381:Rats; D013997:Time Factors; D014699:Venules / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology