title: Unusual solitary metastasis of the ciliary body in renal cell carcinoma.
abstract: Renal cell carcinoma (RCC) usually metastasizes to the lung, liver, bone; ocular metastasis is uncommon. We describe a rare case of metachronous ciliary RCC metastasis in a 42-year-old man who had undergone left radical nephrectomy for conventional RCC (pT3aN0M0, G2 Fuhrman) 6 years earlier. Solitary metastasis of the left eye presented with inflammatory symptoms, but examination of the fundus and bulbar ultrasound revealed a small mass of the ciliary body. Initial radiotherapy was unsuccessful and definitive treatment consisted of ocular enucleation with radical result and no further evidence of local and distant disease. Ocular metastasis of RCC is rare, can appear years after treating the primary tumor and should not be excluded in RCC follow-up. As for other RCC solitary metastasis, the best option remains the radical surgical approach.
authors.affiliation: Urology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation (DETO), University of Bari, Italy. vito.mancini@libero.it
authors.forename: Vito
authors.initials: V
authors.lastname: Mancini
authors.forename: Michele
authors.initials: M
authors.lastname: Battaglia
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lucarelli
authors.forename: Vito
authors.initials: V
authors.lastname: Di Lorenzo
authors.forename: Pasquale
authors.initials: P
authors.lastname: Ditonno
authors.forename: Carlo
authors.initials: C
authors.lastname: Bettocchi
authors.forename: Francesco Paolo
authors.initials: FP
authors.lastname: Selvaggi
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000556:secondary*; D002924:Ciliary Body / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D014604:Uveal Neoplasms / Q000556:secondary*