title: In vitro activity of anidulafungin against Candida albicans biofilms.
abstract: We tested the activity of anidulafungin against 30 Candida albicans isolates. The planktonic MICs for 50 and 90% of the isolates tested (MIC(50) and MIC(90)) were < or =0.03 and 0.125 microg/ml, respectively (MIC range, < or =0.03 to 2 microg/ml). The sessile MIC(50) and MIC(90) were < or =0.03 and < or =0.03 microg/ml, respectively (MIC range, < or =0.03 to >16 microg/ml).
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors.forename: Melissa J
authors.initials: MJ
authors.lastname: Jacobson
authors.forename: Kerryl E
authors.initials: KE
authors.lastname: Piper
authors.forename: Gary
authors.initials: G
authors.lastname: Nguyen
authors.forename: James M
authors.initials: JM
authors.lastname: Steckelberg
authors.forename: Robin
authors.initials: R
authors.lastname: Patel
mesh_terms: D000077612:Anidulafungin; D000935:Antifungal Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D002177:Candidiasis / Q000382:microbiology; D025141:Drug Resistance, Fungal; D054714:Echinocandins / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000592:standards
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D000077612:Anidulafungin