Recombinant factor VIIa for intraoperative bleeding in a child with hepatoblastoma and review of recombinant activated factor VIIa use in children undergoing surgery.
We report a case of a child with a large liver mass who underwent an open liver biopsy and had massive bleeding intraoperatively. Recombinant activated factor VII (rFVIIa) given intraoperatively was successful in stopping the bleeding. We also reviewed the literature on the use of rFVIIa in pediatric surgery.
Al-Said
Khoula
K
Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada T3B 6A8. khoula.al-said@calgaryhealthregion.ca
Anderson
Ronald
R
Wong
Andrew
A
Le
Doan
D
D001706:Biopsy / Q000009:adverse effects; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002675:Child, Preschool; D017707:Erythrocyte Transfusion; D015942:Factor VIIa / Q000627:therapeutic use*; D018197:Hepatoblastoma / Q000601:surgery*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa