Studies on a new biosynthetic pathway for menaquinone.
Menaquinone is biosynthesized from chorismate via a new pathway involving 1,4-dihydroxy-6-naphthoate in Streptomyces and presumably in pathogenic bacteria Helicobacter and Campylobacter.
Seto
Haruo
H
Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo 156-8502, Japan. haseto@nodai.ac.jp
Jinnai
Yuusuke
Y
Hiratsuka
Tomoshige
T
Fukawa
Miwako
M
Furihata
Kazuo
K
Itoh
Nobuya
N
Dairi
Tohru
T
D002167:Campylobacter / Q000378:metabolism; D002244:Carbon / Q000737:chemistry; D002250:Carbon Radioisotopes / Q000737:chemistry; D002827:Chorismic Acid / Q000737:chemistry / Q000378:metabolism*; D005947:Glucose / Q000737:chemistry; D016998:Helicobacter / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D009284:Naphthols / Q000737:chemistry / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism; D024482:Vitamin K 2 / Q000737:chemistry / Q000378:metabolism*; D014815:Vitamins / Q000096:biosynthesis* / Q000737:chemistry
D002250:Carbon Radioisotopes; D009284:Naphthols; D014815:Vitamins; D024482:Vitamin K 2; D002244:Carbon; D002827:Chorismic Acid; D005947:Glucose