New strategies and methods in the discovery of natural product anti-infective agents: the mannopeptimycins.
Koehn
Frank E
FE
Natural Products Discovery, Chemical and Screening Sciences, Wyeth Research, Pearl River, New York 10965, USA. koehnf@wyeth.com
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006020:Glycopeptides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D001688:Biological Products; D006020:Glycopeptides; C478082:mannopeptimycin