Cystic struma ovarii (with macrocystic change).
In this article, a case of cystic struma ovarii with macrocystic change is presented. Cysts derived from struma ovarii may mimic a mucinous or serous cystadenoma. A careful examination for any thyroid microfollicles within fibrous septa or areas of solid stroma is key. In problematic cases, immunohistochemical staining with thyroglobulin and thyroid transcription factor-1 may be required to establish the diagnosis.
Piragua
Sandra C
SC
Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts, USA.
Otis
Christopher N
CN
Prefontaine
Michel
M
Pantanowitz
Liron
L
D000368:Aged; D003560:Cysts / Q000473:pathology*; D005260:Female; D006042:Goiter / Q000150:complications; D006801:Humans; D007150:Immunohistochemistry; D009687:Nuclear Proteins / Q000096:biosynthesis; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology*; D013330:Struma Ovarii / Q000150:complications / Q000473:pathology*; D000074482:Thyroid Nuclear Factor 1; D013965:Thyroidectomy; D014157:Transcription Factors / Q000096:biosynthesis
C000614412:NKX2-1 protein, human; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors