title: Myocardial infarction in a 28-year-old thalassemia intermedia patient.
abstract: A 28-year-old Lebanese thalassemia intermedia (TI) patient with homozygous IVS1-110 mutation sustained atypical chest pain of 1 day's duration. The EKG reading revealed ST segment elevation in the chest leads V(1) to V(5). Coronary angiography showed 2 plaques in the left anterior descending coronary artery. He underwent subsequent angioplasty with stenting of the left anterior descending coronary artery. An extensive thrombophilia profile was negative. He was started on medication, and his medical condition improved and chest pain ceased. This is the first case report of myocardial infarction in a TI patient among thalassemics. We propose that such cases will emerge more frequently as our population ages, keeping in mind a possible thrombotic mechanism.
authors.affiliation: American University of Beirut Medical Center, Riad El Solh 1107, Beirut, Lebanon.
authors.forename: Fuad A
authors.initials: FA
authors.lastname: El Rassi
authors.forename: Hussain A
authors.initials: HA
authors.lastname: Ismaeel
authors.forename: Suzanne C
authors.initials: SC
authors.lastname: Koussa
authors.forename: Ali T
authors.initials: AT
authors.lastname: Taher
mesh_terms: D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D006720:Homozygote; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D015607:Stents; D013927:Thrombosis / Q000150:complications* / Q000235:genetics; D017086:beta-Thalassemia / Q000150:complications* / Q000235:genetics