title: Percutaneous closure of a large PDA in a 35-year-old man with elevated pulmonary vascular resistance.
abstract: The presence of a large patent ductus arteriosus (PDA) may result in significant pulmonary hypertension, which may not be reversible. We present the case of a 35-year-old man with pulmonary hypertension who had successful percutaneous closure of a large PDA with an Amplatzer muscular ventricular septal defect occluder and resolution of his pulmonary hypertension. The use of prior balloon test occlusion of the PDA suggested that the procedure would be successful, despite the lack of an immediate fall in the pulmonary artery pressure.
authors.affiliation: Pediatric Cardiology, University of Wisconsin, Madison, WI 53792, USA. jhokanson@wisc.edu
authors.forename: John S
authors.initials: JS
authors.lastname: Hokanson
authors.forename: Giorgio
authors.initials: G
authors.lastname: Gimelli
authors.forename: John L
authors.initials: JL
authors.lastname: Bass
mesh_terms: D000328:Adult; D021721:Balloon Occlusion; D006328:Cardiac Catheterization / Q000379:methods; D004374:Ductus Arteriosus, Patent / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D004452:Echocardiography; D004867:Equipment Design; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D018810:Magnetic Resonance Angiography; D008297:Male; D019919:Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*