title: Impact of substance dependence and dual diagnosis on the quality of life of heroin users seeking treatment.
abstract: In 189 opioid-dependent subjects on methadone maintenance treatment in Barcelona (Spain), we assessed the prevalence of co-occurrence substance use and non-substance-use disorders (dual diagnosis) by the Psychiatric Research Interview for Substance and Mental Disorders [PRISM], and the impact on quality of life (HRQoL) by the SF-12 (PCS-12 and MCS-12 scales). Rates of substance and non-substance-use diagnoses were 59% and 32%, respectively. Mean scores for PCS-12 and MCS-12 were 44.1+/-10.1 and 39.9+/-11.7, without differences by presence or absence of dual diagnosis. Heroin users on methadone treatment showed a high prevalence of dual diagnosis and a very impaired HRQoL.
authors.affiliation: Department of Psychiatry and Drug Abuse and Psychiatric Research Group, Hospital del Mar (IAPS) and Institut Municipal d'Investigació Mèdica (IMIM), and Departament de Psiquiatria i Medicina Legal, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors.forename: Mònica
authors.initials: M
authors.lastname: Astals
authors.forename: Antònia
authors.initials: A
authors.lastname: Domingo-Salvany
authors.forename: Claudio Castillo
authors.initials: CC
authors.lastname: Buenaventura
authors.forename: Jordi
authors.initials: J
authors.lastname: Tato
authors.forename: José Ma
authors.initials: JM
authors.lastname: Vazquez
authors.forename: Rocío
authors.initials: R
authors.lastname: Martín-Santos
authors.forename: Marta
authors.initials: M
authors.lastname: Torrens
mesh_terms: D000328:Adult; D000987:Antisocial Personality Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D015897:Comorbidity; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006304:Health Status; D006556:Heroin Dependence / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D008691:Methadone / Q000627:therapeutic use; D010342:Patient Acceptance of Health Care / Q000523:psychology; D015995:Prevalence; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011788:Quality of Life; D013030:Spain / Q000453:epidemiology; D016320:Substance Abuse Treatment Centers / Q000706:statistics & numerical data
chemical_list: D008691:Methadone