Pediatric hypothyroidism presenting with a polymyositis-like syndrome and increased creatinine: report of three cases.
We report three pediatric cases of primary hypothyroidism presenting with musculoskeletal complaints, elevated muscle enzymes and increased creatinine. Thyroid hormone replacement led to improvement in both the clinical features and laboratory abnormalities.
Sbrocchi
Anne Marie
AM
Department of Pediatrics, Divisions of Rheumatology and Endocrinology, Montreal Children's Hospital, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
Chédeville
Gaëlle
G
Scuccimarri
Rosie
R
Duffy
Ciarán M
CM
Krishnamoorthy
Preetha
P
D002648:Child; D003404:Creatinine / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D008297:Male; D017285:Polymyositis / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D013577:Syndrome; D013960:Thyroid Function Tests
D003404:Creatinine