[Diagnosis and treatment of non-specific granulomatous prostatitis: a report of 32 cases].
OBJECTIVE
To discuss the diagnosis and treatment of non-specific granulomatous prostatitis (NSGP).


METHODS
Thirty-two cases of NSGP were diagnosed by puncture biopsy under transrectal ultrasound (TRUS) and treated with antibiotics and other medicines from September, 2000 to May, 2006.


RESULTS
Pathomorphologically, NSGP was basically characterized by granuloma with vessels or grand alveoli in the center. The mean follow-up was 24 months. Urination irritation and obstruction were improved. Q(max) was increased to 15.0-24.0 ml/s, and in 3 cases of urinary retention, to 12.0, 14.5 and 16.5 ml/s, respectively. Digital rectal examination (DRE) indicated a reduced size and softened texture of the prostate induration. PSA was decreased to 1.3-11.5 microg/L. Four cases experienced relapse but were cured after retreated. No prostate cancer was observed.


CONCLUSIONS
NSGP can be definitely diagnosed by puncture biopsy under TRUS and effectively relieved by antibiotics with the alpha-receptor blocker. In case of serious obstruction complicated by urinary retention, transurethral electrotomy can be considered.
Fan
Hai-Tao
HT
Department of Urology, Second Hospital of Jilin University, Changchun, Jilin 130041, China. jlfanht@sina.com
Wang
Kai-Chen
KC
Zhang
Mu-Chun
MC
Wang
Wei-Hua
WH
Ji
Guo-Yi
GY
Wang
Yao
Y
Kong
Xiang-Bo
XB
D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006099:Granuloma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011472:Prostatitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D012007:Rectum; D014463:Ultrasonography / Q000379:methods
D000317:Adrenergic alpha-Antagonists; D000900:Anti-Bacterial Agents