Self-assembly of a peptide rod-coil: a polyproline rod and a cell-penetrating peptide Tat coil.
Peptide rod-coil molecules, composed of a stiff polyproline rod and a hydrophilic cell-penetrating peptide Tat coil, self-assemble into nanocapsules and mediate efficient intracellular delivery of entrapped hydrophilic molecules.
Yoon
You-Rim
YR
Centre for Supramolecular Nano-Assembly, Department of Chemistry, Yonsei University, Shinchon 134, Seoul, 120-749, Korea.
Lim
Yong-beom
YB
Lee
Eunji
E
Lee
Myongsoo
M
D002463:Cell Membrane Permeability; D002942:Circular Dichroism; D015696:Gene Products, tat / Q000737:chemistry* / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism*
D015696:Gene Products, tat; D010455:Peptides; C011083:polyproline