title: [Heat stroke and topiramate].
abstract: Heatstroke, which is a major disorder related to environmental hyperthermia, is a rare event in children. The risk is increased with predisposing medical conditions and specific medications. We report the case of a 10-year-old epileptic patient, who received topiramate. Topiramate causes hypohydrosis and hyperthermia. We suggest that topiramate treatment may be a risk factor for heatstroke.
authors.affiliation: Unité de réanimation pédiatrique, service de pédiatrie centre hospitalier du Mans, 194 avenue Rubillard, Le Mans cedex, France. tboussemart@ch-lemans.fr
authors.forename: T
authors.initials: T
authors.lastname: Boussemart
authors.forename: V
authors.initials: V
authors.lastname: Flurin
authors.forename: F
authors.initials: F
authors.lastname: Labay-Bruneau
authors.forename: J-M
authors.initials: JM
authors.lastname: Bonardi
mesh_terms: D002648:Child; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D018883:Heat Stroke / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D008297:Male; D018696:Neuroprotective Agents / Q000009:adverse effects*; D012307:Risk Factors; D000077236:Topiramate
chemical_list: D018696:Neuroprotective Agents; D000077236:Topiramate; D005632:Fructose