Recurrent facial nerve palsy associated with anti-GQ1b IgG antibodies.
Recurrent facial nerve palsy (RFNP) in childhood is usually considered to be a benign disorder. We report a 13-year-old female affected with RFNP in the absence of other neurologic signs, in which elevated serum IgG and IgM anti-GQ1b antibodies were detected. To our knowledge, this is the first example in the literature of RFNP, associated with anti-GQ1b IgG antibodies. The possible role of anti-GQ1b antibodies in isolated cranial neuropathy is discussed.
Greco
Filippo
F
Department of Pediatrics, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. coicoico@hotmail.com
Barbagallo
Maria Luisa
ML
Guglielmino
Rosanna
R
Sorge
Giovanni
G
D000293:Adolescent; D001323:Autoantibodies / Q000097:blood* / Q000276:immunology; D005155:Facial Nerve Diseases / Q000276:immunology*; D005158:Facial Paralysis / Q000276:immunology*; D005260:Female; D005732:Gangliosides / Q000276:immunology*; D006801:Humans
D001323:Autoantibodies; D005732:Gangliosides; C039129:GQ1b ganglioside