Chemical approaches to mapping the function of post-translational modifications.
Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes.
Gamblin
David P
DP
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, UK.
van Kasteren
Sander I
SI
Chalker
Justin M
JM
Davis
Benjamin G
BG
D000818:Animals; D005544:Forecasting; D006023:Glycoproteins / Q000096:biosynthesis; D006031:Glycosylation; D006801:Humans; D008958:Models, Molecular; D018716:Molecular Mimicry; D025941:Protein Interaction Mapping; D011499:Protein Processing, Post-Translational
D006023:Glycoproteins