title: [Clinical analysis of primary small intestinal neoplasms in 305 cases].
abstract: OBJECTIVE
  To summarive the experience in diagnosis and treatment of primary small intestinal neoplasm.
  
  
  METHODS
  The data of 305 patients with pathologically confirmed primary small intestinal tumor collected from 6 hospitals around the Songhua River during the past 33 years were analyzed retrospectively.
  
  
  RESULTS
  There were 42 benign and 263 malignant tumors in this series with a ratio of 1: 6.26. The 263 malignant tumors in this series consisted of 135 adenocarcinomas, 57 malignant stromal tumors, 37 malignant lymphomas, 20 carcinoids, and etc. Chronic occult bleeding, gradual of body weight loss and mild abdominal pain (three obscurities) were the common clinical features and alerting massage of intestinal tumor. Correct preoperative diagnostic rate was only 57.0% (174/305) due to difficulty in early diagnosis, which was 67.2% (92/137) in the duodenal tumors, and 51.9% (82/168) in the jejunoileal tumors. All of the 42 benign tumors were resected completely. For the 263 patients with malignant tumors, radical dissection was performed in 153, palliative resection in 34, and gut by-pass or biopsy in 76. The median survival of the patients who underwent radical resection of their malignant tumors was 92 months, which was significantly higher than that of the other groups.
  
  
  CONCLUSIONS
  Early diagnosis of primary small intestinal tumors is difficult and with a preoperative misdiagnosis rate of 43.0%. Total intestinal barium swallowing, endoscopy and superior mesenteric arteriography are three critical examinations for diagnosis and location. Early surgical resection is crucial in improving the prognosis. The primary small intestinal tumor should be resected as early as possible if no distant metastasis is detected.
authors.affiliation: Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China. wlyang_2008@163.com
authors.forename: Wei-Liang
authors.initials: WL
authors.lastname: Yang
authors.forename: Xin-Chen
authors.initials: XC
authors.lastname: Zhang
authors.forename: Zhao-Qi
authors.initials: ZQ
authors.lastname: Yan
authors.forename: Hao-Min
authors.initials: HM
authors.lastname: Zhang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zhao
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Zhang
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D003951:Diagnostic Errors; D013505:Digestive System Surgical Procedures / Q000379:methods*; D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D055815:Young Adult