Biliary wall calcification in Langerhans cell histiocytosis: report of two cases.
Langerhans cell histiocytosis (LCH) is a disorder of unknown pathogenesis affecting one or more organs (unifocal or disseminated form) due to clonal proliferation of Langerhans cells. Liver involvement is more frequent in the disseminated form and the radiological findings of end-stage liver disease due to LCH are similar to those of sclerosing cholangitis. We present the multidetector CT findings in two children with LCH liver involvement and the unique finding of calcification of the biliary wall.
Caruso
Settimo
S
Department of Diagnostic and Interventional Radiology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT), Via Ernesto Tricomi 1, 90127, Palermo, Italy.
Miraglia
Roberto
R
Maruzzelli
Luigi
L
Luca
Angelo
A
Gridelli
Bruno
B
D001659:Biliary Tract / Q000000981:diagnostic imaging / Q000473:pathology*; D001706:Biopsy; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D017809:Fatal Outcome; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography