title: The cyanoacrylate topical skin adhesives.
abstract: Each year there are over 7 million lacerations requiring wound closure in the emergency department. Traditionally, most lacerations have been closed with sutures. Topical cyanoacrylate skin adhesives offer many advantages over traditional wound closure devices. Recently, the Food and Drug Administration (FDA) has reclassified the topical skin adhesives. As a result, new topical skin adhesives are expected to enter the market in the near future. This article will review the structure and function of cyanoacrylates as well as their advantages, indications, and usage.
authors.affiliation: Department of Emergency Medicine, University Hospital, Stony Brook, NY 11794-7400, USA. adam.singer@stonybrook.edu
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Singer
authors.forename: James V
authors.initials: JV
authors.lastname: Quinn
authors.forename: Judd E
authors.initials: JE
authors.lastname: Hollander
mesh_terms: D000287:Administration, Topical; D003487:Cyanoacrylates / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D022125:Lacerations / Q000628:therapy*; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000008:administration & dosage* / Q000494:pharmacology; D014947:Wounds and Injuries / Q000628:therapy
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives