title: Activation in prochiral reaction assemblies on Pt(111).
abstract: Trifluoroacetophenone (TFAP) forms C O...H-C bonded dimers and trimers at room temperature on Pt(111). It is proposed that these systems mimic the prochiral carbonyl-chiral modifier interaction in the enantioselective hydrogenation of TFAP on cinchona-modified Pt catalysts. That is, the activation of TFAP in homomolecular assemblies at racemic sites is expected to be roughly the same as in the diastereomeric complex formed at chiral sites. This interpretation suggests a reason why alpha-phenyl ketones do not display a strong measured rate enhancement effect in the Orito reaction.
authors.affiliation: Département de Chimie, Université Laval, Québec, QC, Canada G1K 7P4.
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Laliberté
authors.forename: Stéphane
authors.initials: S
authors.lastname: Lavoie
authors.forename: Bjørk
authors.initials: B
authors.lastname: Hammer
authors.forename: Gautier
authors.initials: G
authors.lastname: Mahieu
authors.forename: Peter H
authors.initials: PH
authors.lastname: McBreen