title: Revised optimal cut-off point of waist circumference for the diagnosis of metabolic syndrome in Japanese women and the influence of height.
abstract: OBJECTIVE
  We reevaluated waist circumference as a diagnostic criterion of metabolic syndrome (MetS) in Japanese.
  
  
  METHODS
  We enrolled 5,571 subjects (3,148 men and 2,423 women) who had health check-ups in our center. The criterion was reevaluated using the positive predictive value of a receiver-operating characteristics (ROC) curve at 10 different hypothesized lengths of waist circumference with or without a cluster of risk factors. We also drew ROC curves based on the atherosclerotic findings of clinical examinations.
  
  
  RESULTS
  Based on the ROC curves, the optimal waist circumference cut-off was 85 cm in men and 80 cm in women. Using this 80 cm cut-off point in women, misdiagnosis rates of MetS were lowered (-19.1--56.6%) compared to the cut-off point currently in use. Integrating the influence of height, namely by using a waist-to-height(2) ratio, misdiagnosis rates in shorter populations were decreased in both men and women.
  
  
  CONCLUSIONS
  These data suggested an optimal waist circumference cut-off to improve the diagnostic probability of MetS in Japanese women of 80 cm, as well as the utility of an easily detected anthropometric index such as a waist-to-height (cm x 100/cm) or waist-to-height(2) (cm x 10,000/cm(2)) ratio, determined as 51 in men and 52 in women, or 30 in men and 33 in women, respectively.
authors.affiliation: Wakayama Seijinbyo Center, 2-1-2 Tebira, Wakayama City, Wakayama, Japan.
authors.forename: Tsuyako
authors.initials: T
authors.lastname: Shimajiri
authors.forename: Mitsuyo
authors.initials: M
authors.lastname: Imagawa
authors.forename: Mika
authors.initials: M
authors.lastname: Kokawa
authors.forename: Tomomi
authors.initials: T
authors.lastname: Konami
authors.forename: Hitomi
authors.initials: H
authors.lastname: Hara
authors.forename: Inbou
authors.initials: I
authors.lastname: Kyoku
authors.forename: Emiko
authors.initials: E
authors.lastname: Sone
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ishigame
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Kikuoka
mesh_terms: D000886:Anthropometry / Q000379:methods*; D001827:Body Height; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D012737:Sex Factors; D049629:Waist-Hip Ratio