Surface functionalization of porous resorbable scaffolds by covalent grafting.
Resorbable porous scaffold discs and solid films were prepared from poly[(1,5-dioxepan-2-one)-co-(L-lactide)] and poly[(epsilon-caprolactone)-co-(L-lactide)]. The surfaces of the scaffolds were functionalized to increase their hydrophilicity. A total of 90 samples were prepared to cover all important combinations of experimental and material factors, and all experimental data were fitted by a partial least square model. As a result of grafting, the porous discs and solid films exhibited a tremendous increase in wettability. The functionalized discs were hygroscopic so that water was instantly absorbed and thoroughly wet the substrates.
Källrot
Martina
M
Fiber and Polymer Technology, School of Chemical Science and Engineering, Royal Institute of Technology, SE-100 44 Stockholm, Sweden.
Edlund
Ulrica
U
Albertsson
Ann-Christine
AC
D000042:Absorption; D057927:Hydrophobic and Hydrophilic Interactions; D011091:Polyesters / Q000737:chemistry*; D016062:Porosity; D014867:Water / Q000737:chemistry*; D017155:Wettability
D011091:Polyesters; D014867:Water; C062968:lactide-caprolactone copolymer