title: Brucellosis in household members of Brucella patients residing in a large urban setting in Peru.
abstract: During home visits and using a point-of-care test for brucellosis, we screened the household members of adult patients found to have brucellosis by investigation at the Hospital Nacional Daniel Alcides Carrión in Callao, Peru. A total of 206 household members of 43 patients were screened, and 15 (7.3%) household members in 10 (23.3%) households tested seropositive. Brucellosis was diagnosed in 14 of them, all but 4 presenting with acute or subacute uncomplicated disease. Regardless of attempts to control brucellosis in Peru, the disease continues to be reasonably common among household members of brucellosis patients. Household members presumably remain the single most important identifiable risk group in an urban setting, and screening them provides an effective means for their early diagnosis. Although contact with livestock was rare, the consumption of unpasteurized dairy products was reported by almost all patients with brucellosis, their household members, and hospitalized non-brucellosis patients.
authors.affiliation: Department of Infectious Diseases, Hospital Nacional Daniel Alcides Carrión, Gaurdia Chalaca 2176, Callao Peru.
authors.forename: Marjorie
authors.initials: M
authors.lastname: Mendoza-Núñez
authors.forename: Maximilian
authors.initials: M
authors.lastname: Mulder
authors.forename: María Pía
authors.initials: MP
authors.lastname: Franco
authors.forename: Kathlène S J S M
authors.initials: KS
authors.lastname: Maas
authors.forename: Maria L
authors.initials: ML
authors.lastname: Castañeda
authors.forename: Nilo
authors.initials: N
authors.lastname: Bonifacio
authors.forename: Jesús
authors.initials: J
authors.lastname: Chacaltana
authors.forename: Elena
authors.initials: E
authors.lastname: Yagui
authors.forename: Robert H
authors.initials: RH
authors.lastname: Gilman
authors.forename: Benjamin
authors.initials: B
authors.lastname: Espinosa
authors.forename: David
authors.initials: D
authors.lastname: Blazes
authors.forename: Eric
authors.initials: E
authors.lastname: Hall
authors.forename: Theresia H
authors.initials: TH
authors.lastname: Abdoel
authors.forename: Henk L
authors.initials: HL
authors.lastname: Smits
mesh_terms: D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000097:blood; D002006:Brucellosis / Q000453:epidemiology* / Q000517:prevention & control; D005191:Family Characteristics; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008403:Mass Screening; D010297:Paris / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data*
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M