Ring-closing metathesis: novel routes to aromatic heterocycles.
Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.
Donohoe
Timothy J
TJ
Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA UK. timothy.donohoe@chem.ox.ac.uk
Fishlock
Lisa P
LP
Procopiou
Panayiotis A
PA
D000475:Alkenes / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis; D008956:Models, Chemical; D011725:Pyridines / Q000138:chemical synthesis; D011758:Pyrroles / Q000138:chemical synthesis; D013237:Stereoisomerism
D000475:Alkenes; D005663:Furans; D006571:Heterocyclic Compounds; D006841:Hydrocarbons, Aromatic; D007211:Indoles; D011725:Pyridines; D011758:Pyrroles