title: Staphylococcus aureus: the new adventures of a legendary pathogen.
abstract: Nosocomial infections with strains of methicillin-resistant Staphylococcus aureus (MRSA) began to emerge in the 1960s, are increasing in frequency, and tend to have worse outcomes than infections due to methicillin-susceptible S aureus. Community-associated MRSA infections emerged in the 1990s. Community-associated MRSA strains have up to now been epidemiologically and bacteriologically distinct from hospital-associated MRSA strains, but in a new twist, MRSA strains that have sofar been only community-associated are invading the hospital. Another worrisome trend is increasing resistance to vancomycin (Vancocin).
authors.affiliation: Department of Infectious Disease, Cleveland Clinic Foundation, OH 44195, USA. rehms@ccf.org
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Rehm
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D017714:Community-Acquired Infections / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology; D019115:Fasciitis, Necrotizing / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D016106:Methicillin Resistance; D008875:Middle Aged; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000472:pathogenicity; D014640:Vancomycin / Q000494:pharmacology* / Q000627:therapeutic use; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin