Hypokalemic rhabdomyolysis in a child with 11-hydroxylase deficiency.
Myopathy is a well-recognized complication of persistent hypokalemia. Although hypokalemic myopathy may be due to divers diseases or to drug administration, hypokalemic rhabdomyolysis as a complication of under-treated 11-hydroxylase deficiency has not previously been described in the literature. We describe a 10-year-old boy with under-treated 11-hydroxylase deficiency who developed rhabdomyolysis following severe hypokalemia. Patients with under-treated 11-hydroxylase deficiency may present with hypokalemia in association with muscle weakness; if serum potassium is markedly low, rhabdomyolysis may occur. Hypokalemia-induced rhabdomyolysis should be carefully followed.
Atabek
Mehmet Emre
ME
Department of Pediatric Endocrinology, Faculty of Medicine, Selcuk University, Turkey.
Pirgon
Ozgur
O
Sert
Ahmet
A
D000312:Adrenal Hyperplasia, Congenital / Q000150:complications*; D002648:Child; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000175:diagnosis; D008297:Male; D011188:Potassium / Q000097:blood; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology*; D013252:Steroid 11-beta-Hydroxylase / Q000378:metabolism*
D013252:Steroid 11-beta-Hydroxylase; D011188:Potassium