title: Slice-selective images of free radicals in mice with modulated field gradient electron paramagnetic resonance (EPR) imaging.
abstract: Continuous wave (CW) electron paramagnetic resonance (EPR) imaging can be used to obtain slice-selective images of free radicals without measuring three-dimensional (3D) projection data. A method that incorporated a modulated magnetic field gradient (MFG) was combined with polar field gradients to select a slice in the subject noninvasively. The slice-selective in vivo EPR imaging of triarylmethyl radicals in the heads of live mice is reported. 3D surface-rendered images were successfully obtained from slice-selective images. In the experiment in mice, a slice thickness of 1.8 mm was achieved.
authors.affiliation: Department of Electrical Engineering, Yamagata University, Yonezawa, Yamagata, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Sato-Akaba
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Abe
authors.forename: Hirotada
authors.initials: H
authors.lastname: Fujii
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hirata
mesh_terms: D000465:Algorithms; D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D005609:Free Radicals / Q000378:metabolism*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D005609:Free Radicals; D017382:Reactive Oxygen Species