Microbiological evaluation after gastrectomy and reconstruction for gastric cancer.
The purpose of this study was to evaluate microbial flora in the mucosa of reconstructed organs after gastrectomy for gastric cancer and improve postoperative quality of life by treating the flora. The number of aerobes was significantly higher in the gastric remnant in the proximal gastrectomy-jejunal pouch interposition group (n=8) than the distal gastrectomy-Billroth II reconstruction (G-BII) group (n=2) or the pylorus-preserving gastrectomy (PPG) group (n=8). The mean number and positive rate of anaerobes tended to be higher in jejunal pouch reconstruction groups. No Helicobacter pylori were detected in any specimens after the G-BII and jejunal pouch reconstruction. However, the gastric remnant and duodenum in the distal gastrectomy-Billroth I reconstruction group (n=5; positive rate of 80% and 20%, respectively) and the PPG group (positive rate of 63% and 25%, respectively) showed H. pylori. We concluded that more anaerobes tended to grow in the mucosa of reconstructed organs after jejunal pouch reconstruction than other procedures. Some patients after jejunal pouch reconstruction worried about their halitosis. Therefore, elimination of anaerobes may relieve it and improve postoperative quality of life.
Sekita
Yoshihisa
Y
Department of Surgery, Graduate School of Health Science, Tokyo Medical and Dental University School of Medicine, Tokyo, Japan.
Takeshita
Kimiya
K
Tani
Masao
M
Okamura
Noboru
N
Chida
Toshio
T
Kawano
Tatsuyuki
T
Iwai
Takehisa
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001420:Bacteria, Aerobic; D001421:Bacteria, Anaerobic; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D005753:Gastric Mucosa / Q000382:microbiology*; D005763:Gastroenterostomy / Q000009:adverse effects*; D006209:Halitosis / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000601:surgery*