The importance of histology and cytogenetics in decision making for renal cell carcinoma.
The role of histology and cytogenetics in the diagnosis of renal cell carcinoma continues to evolve. The symbiotic relationship between histology and cytogenetics helps assure the most accurate diagnosis. Prognostic factors are known and continue to be undiscovered. Patient counseling certainly benefits from this information. Further knowledge and differentiation of renal cell carcinoma disease pathways has allowed for the development of targeted therapies. The benefit of these therapies hinges on the critical diagnosis attained via the role of histology and cytogenetics.
Garcia
Julia G
JG
Department of Urology, Loyola University Medical Center, 2160 South First Avenue, Blg 54, Maywood, IL 60153, USA. jugarcia@lumc.edu
Picken
Maria M
MM
Flanigan
Robert C
RC
D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*; D003582:Cytogenetics; D006801:Humans; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*; D011379:Prognosis