title: Barley genomics: An overview.
abstract: Barley (Hordeum vulgare), first domesticated in the Near East, is a well-studied crop in terms of genetics, genomics, and breeding and qualifies as a model plant for Triticeae research. Recent advances made in barley genomics mainly include the following: (i) rapid accumulation of EST sequence data, (ii) growing number of studies on transcriptome, proteome, and metabolome, (iii) new modeling techniques, (iv) availability of genome-wide knockout collections as well as efficient transformation techniques, and (v) the recently started genome sequencing effort. These developments pave the way for a comprehensive functional analysis and understanding of gene expression networks linked to agronomically important traits. Here, we selectively review important technological developments in barley genomics and related fields and discuss the relevance for understanding genotype-phenotype relationships by using approaches such as genetical genomics and association studies. High-throughput genotyping platforms that have recently become available will allow the construction of high-density genetic maps that will further promote marker-assisted selection as well as physical map construction. Systems biology approaches will further enhance our knowledge and largely increase our abilities to design refined breeding strategies on the basis of detailed molecular physiological knowledge.
authors.affiliation: Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung, Gatersleben, Germany. srinivas@ipk-gatersleben.de <srinivas@ipk-gatersleben.de>
authors.forename: Nese
authors.initials: N
authors.lastname: Sreenivasulu
authors.forename: Andreas
authors.initials: A
authors.lastname: Graner
authors.forename: Ulrich
authors.initials: U
authors.lastname: Wobus