title: Phosphorylation by sphingosine kinase 2 is essential for in vivo potency of FTY720 analogues.
authors.affiliation: Novartis Institutes for Biomedical Research, Brunner Strasse 59, 1235 Wien, Austria. klemens.hoegenauer@novartis.com
authors.forename: Klemens
authors.initials: K
authors.lastname: Högenauer
authors.forename: Andreas
authors.initials: A
authors.lastname: Billich
authors.forename: Charles
authors.initials: C
authors.lastname: Pally
authors.forename: Markus
authors.initials: M
authors.lastname: Streiff
authors.forename: Trixie
authors.initials: T
authors.lastname: Wagner
authors.forename: Karl
authors.initials: K
authors.lastname: Welzenbach
authors.forename: Peter
authors.initials: P
authors.lastname: Nussbaumer
mesh_terms: D002384:Catalysis; D000068876:Fingolimod Hydrochloride; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000494:pharmacology*; D008956:Models, Chemical; D010766:Phosphorylation; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000737:chemistry / Q000378:metabolism*; D011409:Propylene Glycols / Q000737:chemistry / Q000494:pharmacology*; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D000099157:Sphingosine Kinase
chemical_list: D000068876:Fingolimod Hydrochloride; D007166:Immunosuppressive Agents; D017853:Phosphotransferases (Alcohol Group Acceptor); D011409:Propylene Glycols; D013110:Sphingosine; D000099157:Sphingosine Kinase