title: [Gastric plasmacytoma as an uncommon cause of upper gastrointestinal bleeding].
abstract: Gastric plasmacytoma is an infrequent form of presentation of monoclonal gammopathy that, if ulcerated, can cause upper gastrointestinal bleeding. This entity is usually localized but may progress to multiple myeloma or other forms of monoclonal gammopathy. Differential diagnosis should be performed with other monoclonal gammopathies, based on laboratory and histological criteria, as well as with other gastric tumors such as adenocarcinoma, gastrointestinal stromal tumors, neuroendocrine tumors and lymphomas. Differential diagnosis can be based on radiological and endoscopic characteristics, although definitive diagnosis will undoubtedly be based on histological study and immunohistochemical techniques. We describe the case of a male patient who underwent investigations for upper gastrointestinal bleeding and iron deficiency anemia. The final diagnosis was multiple myeloma associated with gastric plasmacytoma.
authors.affiliation: Servicio de Aparato Digestivo, Hospital de Navarra, Pamplona, Navarra, Spain. mirva77@hotmail.com
authors.forename: Miren
authors.initials: M
authors.lastname: Vicuña Arregui
authors.forename: Erika
authors.initials: E
authors.lastname: Borobio Aguilar
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Vila Costas
authors.forename: M Cruz
authors.initials: MC
authors.lastname: Viguria Alegría
authors.forename: Miren
authors.initials: M
authors.lastname: Arrechea Irigoyen
authors.forename: Fernando
authors.initials: F
authors.lastname: Borda Celaya
authors.forename: José María
authors.initials: JM
authors.lastname: Martínez-Peñuela Vinseda
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis; D008297:Male; D008551:Melena / Q000209:etiology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis; D009378:Neoplasms, Multiple Primary; D010954:Plasmacytoma / Q000150:complications* / Q000175:diagnosis; D012004:Rectal Neoplasms; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis; D013276:Stomach Ulcer / Q000209:etiology