title: Revival of an old method with new techniques: balloon aortic valvuloplasty of the calcified aortic stenosis in the elderly.
abstract: Balloon aortic valvuloplasty (BAV), introduced since almost 20 years, has experienced a revival for its use in the treatment of elderly patients with severe calcified aortic stenosis that are associated with high operative risk and co-morbidities. This is due to the introduction of new balloon catheters and techniques. This study reports about 75 such cases performed within the past 28 months. The mean age of our patient group was 78 +/- 7 years (median = 80 years). Risk calculation with the EuroSCORE demonstrated an average value of 24.4 +/- 19.5%. BAV was performed along with burst pacing to reduce transvalvular blood flow for stabilization of the balloon catheter until blood pressure dropped to less than 50 mmHg. BAV was performed in 72 patients with a procedural success rate of 73%. There was a decrease of 31 mmHg peak-to-peak gradient across the aortic valve from 63 +/- 35 to 32 +/- 22 mmHg (P < 0.0001). Mean gradient was reduced from 51 +/- 24 to 27 +/- 15 mmHg (P < 0.0001). Aortic valve area increased by 49% from 0.84 +/- 0.33 to 1.25 +/- 0.45 cm(2) (P < 0.0001). Serious adverse events (SAE) occurred in 17% of the 75 BAV procedures. Follow-up revealed a significant improvement in 6-month and 1-year survival. The improved technology of BAV makes this technique attractive for elderly patients who are at high operative risk or in cases where valve replacement was refused for any reason.
authors.affiliation: Klinik für Kardiologie, Westdeutsches Herzzentrum Essen, Zentrum für Innere Medizin, Universitätsklinikum Essen, Hufelandstrasse 55, 45122, Essen, Germany. stefan.sack@uk-essen.de
authors.forename: Stefan
authors.initials: S
authors.lastname: Sack
authors.forename: Philipp
authors.initials: P
authors.lastname: Kahlert
authors.forename: Sasan
authors.initials: S
authors.lastname: Khandanpour
authors.forename: Christoph
authors.initials: C
authors.lastname: Naber
authors.forename: Sebastian
authors.initials: S
authors.lastname: Philipp
authors.forename: Stefan
authors.initials: S
authors.lastname: Möhlenkamp
authors.forename: Burkhard
authors.initials: B
authors.lastname: Sievers
authors.forename: Hagen
authors.initials: H
authors.lastname: Kälsch
authors.forename: Raimund
authors.initials: R
authors.lastname: Erbel
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D002114:Calcinosis / Q000150:complications* / Q000401:mortality / Q000628:therapy; D009202:Cardiomyopathies / Q000150:complications* / Q000401:mortality / Q000628:therapy; D002404:Catheterization / Q000379:methods*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D015996:Survival Rate; D016896:Treatment Outcome