[Evaluation on the role of hepatitis A vaccine in the prevention and control of hepatitis A in Tianjin city].
OBJECTIVE
To evaluate the effects of prevention and control strategies on hepatitis A.


METHODS
Surveillance data on hepatitis A from 1990 to 2006 in Tianjin was analyzed, and the coverage rate of hepatitis A vaccine among targeted population was estimated, to compare the anti-HAV IgG level of children younger than 15 years old in 1999 and in 2005.


RESULTS
Results showed that a) the morbidity of hepatitis A decreased from 25.26/10(5) in 1990 to 0.82/10(5) in 2006; b) the ratio of hepatitis A in viral hepatitis decreased from 30.43% in 1990 to 1.05% in 2006; c) the estimated coverage rate was 72.7%; d) the positive rate of anti-HAV among children younger than 15 years old in 2005 was distinctly higher than that in 1999.


CONCLUSIONS
Positive results showed that it was successful to use hepatitis A vaccine as the strategy to prevent and control hepatitis A in the past five years in Tianjin.
Zhang
Zhi-lun
ZL
Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.
Zhu
Xiang-jun
XJ
Ding
Ya-xing
YX
Xie
Xiao-hua
XH
Gao
Zhi-gang
ZG
Li
Yong-cheng
YC
Zhang
Ying
Y
Xia
Wei-dong
WD
Liu
Yong
Y
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D006506:Hepatitis A / Q000453:epidemiology* / Q000517:prevention & control*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage*; D006508:Hepatitis Antibodies / Q000097:blood; D006801:Humans; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D011159:Population Surveillance
D022362:Hepatitis A Vaccines; D006508:Hepatitis Antibodies