title: [Correlation between serum uric acid and insulin resistance].
abstract: OBJECTIVE
  To assess the correlation between serum uric acid and insulin resistance in natural population of Beijing.
  
  
  METHODS
  1 056 people without-diabetes, 460 males and 596 females, aged 35-64 was selected from the natural population in Beijing using stratified-random sampling method. Serum uric acid, fasting blood glucose, insulin and other metabolic parameters were measured. The insulin activity index (IAI) was calculated to assess insulin resistance.
  
  
  RESULTS
  The natural logarithm of IAI was decreased with the elevation of serum uric acid level (F = 47.884, P < 0.001). The prevalence of insulin resistance increased with the elevation of uric acid level, from 13.8% in quartile 1 to 33.9% in quartile 4. Compared to the quartile 1, the odds ratio (OR) of the quartile 2 for prevalence of insulin resistance was 1.935; the OR of the quartile 3 was 1.590; the OR of the quartile 4 was 2. 088. Uric acid was independently correlated with insulin resistance after adjustment for sex, age and main components of metabolic syndrome (MS).
  
  
  CONCLUSIONS
  Serum uric acid is correlated with insulin resistance in Beijing natural population after adjustment of sex, age, and the main components of MS.
authors.affiliation: Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Wang
authors.forename: Dong
authors.initials: D
authors.lastname: Zhao
authors.forename: Guang-Wei
authors.initials: GW
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Sa
authors.initials: S
authors.lastname: Liu
authors.forename: Lan-Ping
authors.initials: LP
authors.lastname: Qin
authors.forename: Guang-Hua
authors.initials: GH
authors.lastname: Zhou
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology; D008875:Middle Aged; D016011:Normal Distribution; D014527:Uric Acid / Q000097:blood*
chemical_list: D001786:Blood Glucose; D007328:Insulin; D014527:Uric Acid