title: Crystallization of an Lhx3-Isl1 complex.
abstract: A stable intramolecular complex comprising the LIM domains of the LIM-homeodomain protein Lhx3 tethered to a peptide region of Isl1 has been engineered, purified and crystallized. The monoclinic crystals belong to space group C2, with unit-cell parameters a = 119, b = 62.2, c = 51.9 A, beta = 91.6 degrees , and diffract to 2.05 A resolution.
authors.affiliation: School of Molecular and Microbial Biosciences, The University of Sydney, Australia.
authors.forename: Mugdha
authors.initials: M
authors.lastname: Bhati
authors.forename: Mihwa
authors.initials: M
authors.lastname: Lee
authors.forename: Amy Louise
authors.initials: AL
authors.lastname: Nancarrow
authors.forename: Ingolf
authors.initials: I
authors.lastname: Bach
authors.forename: J Mitchell
authors.initials: JM
authors.lastname: Guss
authors.forename: Jacqueline Mary
authors.initials: JM
authors.lastname: Matthews
mesh_terms: D003460:Crystallization; D005822:Genetic Vectors / Q000138:chemical synthesis; D018398:Homeodomain Proteins / Q000096:biosynthesis / Q000138:chemical synthesis / Q000737:chemistry* / Q000235:genetics; D060850:LIM-Homeodomain Proteins; D015202:Protein Engineering; D014157:Transcription Factors; D016335:Zinc Fingers / Q000235:genetics
chemical_list: D018398:Homeodomain Proteins; D060850:LIM-Homeodomain Proteins; C094898:Lhx3 protein; D014157:Transcription Factors