Fresh frozen plasma transfusion for reversal of prolonged post-anaesthesia apnoea.
An 18-year old woman admitted for tonsillectomy developed prolonged post-operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fresh frozen plasma was associated with reversal of the respiratory paralysis and complete recovery.
van Gammeren
A J
AJ
Department of Clinical Chemistry and Haematology, Amphia Hospital, The Netherlands. avangammeren@amphia.nl
Cobbaert
C M
CM
Schrauwen
C J M
CJ
Voets
M A J
MA
Ermens
A A M
AA
D000293:Adolescent; D001049:Apnea / Q000209:etiology* / Q000628:therapy*; D001803:Blood Transfusion / Q000379:methods*; D005260:Female; D006801:Humans; D010243:Paralysis / Q000209:etiology; D010949:Plasma; D011183:Postoperative Complications / Q000628:therapy*; D014068:Tonsillectomy / Q000009:adverse effects