Demyelinating disease in patients with myasthenia gravis.
Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.
Bichuetti
Denis Bernardi
DB
Neurology and Neurosurgery Department, Federal University of São Paulo, São Paulo, SP, Brazil. denisbichuetti@globo.com
Barros
Tatiane Martins de
TM
Oliveira
Enedina Maria Lobato
EM
Annes
Marcelo
M
Gabbai
Alberto Alain
AA
D000328:Adult; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications*; D009471:Neuromyelitis Optica / Q000175:diagnosis / Q000209:etiology; D012008:Recurrence