Conjugated polyelectrolyte-DNA complexes for multi-color and one-tube SNP genotyping assays.
The complexes of a cationic conjugated polymer with DNA are designed as new platforms for homogeneous, sensitive and facile fluorescence assays for SNP genotyping, which interface with single-base extension, multi-step FRET and optical amplification properties of conjugated polymers.
Duan
Xinrui
X
Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, People's Republic of China.
Wang
Shu
S
Li
Zhengping
Z
D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D004573:Electrolytes / Q000737:chemistry*; D004735:Energy Transfer; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes; D005838:Genotype; D007202:Indicators and Reagents; D011108:Polymers; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D013056:Spectrophotometry, Ultraviolet
D004573:Electrolytes; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D011108:Polymers; D004247:DNA