"In vivo" and "in vitro": tests in the diagnosis of trichophyton allergy.
A group of 100 patients with Trichophyton allergy and a control of group of 100 without fungal allergy have been compared in order to evaluate the diagnostic value of skin prick and intradermal tests and assay of Trichophyton specific IgE. The evaluation of sensitivity, specificity efficacy, positive and negative predictive values suggests that skin tests in two steps, prick and intradermal and research of specific IgE must be used to a better diagnostic approach. In cases were allergy is not cleared by antifungal therapy specific immunotherapy is worthwhile to be tried with a great percentage of success.
Palma-Carlos
M L
ML
Clinical Allergy Immunology Center, Lisbon, Portugal.
Palma-Carlos
A G
AG
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000276:immunology; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology*; D007428:Intradermal Tests; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D012882:Skin Tests; D014249:Trichophyton / Q000276:immunology*
D000485:Allergens; D000935:Antifungal Agents; D017964:Itraconazole; D007073:Immunoglobulin E