Two new lignan glucosides from the fruit of Vitex cannabifolia.
Two new phenyldihydronaphthalene-type lignan glucosides, vitecannasides A (1) and B (2) were isolated from the fruit of Vitex cannabifolia Sieb. et. Zucc. (Verbenaceae) along with the six known lignan derivatives (3-8), four known iridoid glucosides (9-12), three known flavonoids (13-15), and one known phenylbutanone glucoside (16). Their chemical structures were determined on the basis of spectroscopic data as well as chemical evidence. The scavenging effect of 1, 2, and 11-16 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 2, 14, and 15 exhibited stronger activity than that of L: -cysteine. Especially, 14 and 15 showed more potent activity than that of alpha-tocopherol.
Yamasaki
Toru
T
School of Agriculture, Kyushu Tokai University, 5435 Minamiaso, Aso, Kumamoto, 869-1404, Japan.
Kawabata
Tetsuro
T
Masuoka
Chikako
C
Kinjo
Junei
J
Ikeda
Tsuyoshi
T
Nohara
Toshihiro
T
Ono
Masateru
M
D001713:Biphenyl Compounds; D003545:Cysteine / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification*; D005638:Fruit; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010851:Picrates / Q000737:chemistry; D020950:Vitex / Q000737:chemistry*; D024502:alpha-Tocopherol / Q000737:chemistry
D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D005960:Glucosides; D039823:Iridoids; D017705:Lignans; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D024502:alpha-Tocopherol; D003545:Cysteine