title: [Recent progress in epilepsy in neuropathology].
abstract: Epilepsy is a common cerebral disease, and may cause sudden death. Although electric activity study of epileptic brain had been emphasized in the past, the neuropathological study of epilepsy has become a main focus in clinical and forensic medicine recently. This article reviews the recent progress in neuropathology of epilepsy including developmental disorder, abnormal tumoral proliferation, hippocampal sclerosis, dual pathological alteration, and mossy fiber sprouting. Its significance in forensic medicine, particularly for the diagnosis of sudden unexpected death in epilepsy, is discussed.
authors.affiliation: Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. hanwen539@163.com
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
authors.forename: Fan
authors.initials: F
authors.lastname: Fan
authors.forename: Ya
authors.initials: Y
authors.lastname: Jie
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Zhu
authors.forename: Liang
authors.initials: L
authors.lastname: Liu
authors.forename: Yi-Wu
authors.initials: YW
authors.lastname: Zhou
mesh_terms: D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D002423:Cause of Death; D003645:Death, Sudden / Q000209:etiology*; D004827:Epilepsy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D049429:Forensic Pathology; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D054220:Malformations of Cortical Development / Q000150:complications / Q000473:pathology; D012598:Sclerosis / Q000150:complications / Q000473:pathology