Signal transduction and the ras gene family: molecular switches of unknown function.
The ras family consists of 20 or more genes that encode small GTP/GDP-binding proteins, of 20-26 kDa, the functions of which are unknown. This article discusses possible roles of the ras proteins in signal transduction and the interaction of p21(ras) and other members of the ras family with GTPase-accelerating proteins (GAPS) that may be regulatory elements of the signaling machinery.
Macara
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Environmental Health Sciences Center, University of Rochester Medical Center, Rochester, NY 14642, USA.
Wolfman
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