Toll-like receptors.
Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. As part of the innate immune system, Toll-like receptors recognise pathogen-associated molecular patterns, highly conserved components that are essential to microbial function. Some of ten toll-like receptors identified in humans are able to recognise several pathogen-associated molecular patterns.
Dasari
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Child Health Research Institute, Women?s and Children?s Hospital, Adelaide, Australia. Pallave.Dasari@adelaide.edu.au
Nicholson
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Zola
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D000818:Animals; D001327:Autoimmune Diseases / Q000503:physiopathology; D006801:Humans; D007239:Infections / Q000503:physiopathology; D008214:Lymphocytes / Q000502:physiology; D008264:Macrophages / Q000502:physiology; D008958:Models, Molecular; D015398:Signal Transduction; D051193:Toll-Like Receptors / Q000737:chemistry* / Q000276:immunology / Q000502:physiology
D051193:Toll-Like Receptors