title: [Increase in extrapulmonary tuberculosis in The Netherlands associated with an increase in the number of residents with non-Dutch nationality; observational study of data from 1993-2001].
abstract: OBJECTIVE
  To describe the epidemiology of extrapulmonary and pulmonary tuberculosis (TB) in The Netherlands between 1993 and 2001, with special attention given to the relationship between disease site and patient nationality.
  
  
  METHODS
  Retrospective descriptive and comparative study.
  
  
  METHODS
  Data were collected from all patients diagnosed with TB and entered in The Netherlands Tuberculosis Register between 1 January 1993 and 31 December 2001. Information on age, sex, nationality, year of diagnosis, culture result, disease site and HIV status was retrieved and compared.
  
  
  RESULTS
  Of the total 13,258 TB patients, 8,216 (62%) had pulmonary TB and 5,042 (38%) had extrapulmonary TB. The proportion of extrapulmonary TB cases increased during the study period. The most common types of extrapulmonary TB were lymphatic TB, pleural TB and TB of the bones and/or joints. Patients with a non-Dutch nationality were diagnosed with extrapulmonary TB more often than Dutch patients.
  
  
  CONCLUSIONS
  The proportional increase in extrapulmonary TB was explained by an increase in the number of inhabitants with non-Western ethnic backgrounds in The Netherlands. Physicians must be aware of the changing clinical picture of TB.
authors.affiliation: KNCV Tuberculosefonds, afd. Onderzoek, Den Haag. l.tebeek@hotmail.com
authors.forename: L A M
authors.initials: LA
authors.lastname: te Beek
authors.forename: M J
authors.initials: MJ
authors.lastname: van der Werf
authors.forename: C
authors.initials: C
authors.lastname: Richter
authors.forename: M W
authors.initials: MW
authors.lastname: Borgdorff
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000208:ethnology; D000293:Adolescent; D000328:Adult; D000349:Africa; D000368:Aged; D001208:Asia; D005006:Ethnicity; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009018:Morocco; D009426:Netherlands / Q000453:epidemiology / Q000208:ethnology; D012042:Registries; D012998:Somalia; D014376:Tuberculosis / Q000145:classification / Q000453:epidemiology* / Q000208:ethnology*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000208:ethnology