Pregnancy outcome following in vitro fertilization-embryo transfer (IVF-ET) in women of more advanced reproductive age with elevated serum follicle stimulating hormone (FSH) levels.
OBJECTIVE
To present data on the chances of pregnancy following in vitro fertilization embryo transfer, according to day 3 serum FSH and age groups in women > or = age 36.


METHODS
Data were analyzed according to three age groups (36-39, 40-42, > or = 43) and five serum FSH ranges (< or = 10, 11-12, 13-14, 15-16, > or = 17).


RESULTS
No live pregnancies were found in women aged > or = 40 with serum FSH > or = 15 mlU/ml but they were seen in women aged 36-39. Live deliveries were seen in women even > or = 43 with serum FSH 13-14 mlU/ml.


CONCLUSIONS
The higher the serum FSH and the greater the age, the lower the chances of successful conception. However, reasonable pregnancy rates are found in women aged > or = 36 with serum FSH > or = 15 mlU/ml and a live delivered pregnancy rate of about 10% can occur even in women aged > or = 43 with mild FSH elevations.
Check
J H
JH
University of Medicine and Dentistry of New Jersey, Camden, NJ, USA. laurie@ccivf.com
Katsoff
B
B
Brasile
D
D
Choe
J K
JK
Amui
J
J
D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology* / Q000628:therapy; D050498:Live Birth; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies
D005640:Follicle Stimulating Hormone