Antithrombotic therapy in peripheral arterial disease.
The management of elderly patients with peripheral arterial disease requires a multidisciplinary and individualized approach, especially for patients requiring intervention and for those on antithrombotic therapy. Communication between the patient's primary physician, consulting medical specialists, and vascular surgeon is essential because all may contribute synergistically to deliver optimal care to the patient. This article reviews the pathophysiology of peripheral arterial disease and data regarding the use of antiplatelet and anticoagulant agents.
Lipsitz
Evan C
EC
Division of Vascular and Endovascular Surgery, Vascular Diagnostic Laboratory Services, Montefiore Medical Center and the Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY 10467, USA. elipsitz@aol.com
Kim
Soo
S
D000925:Anticoagulants / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage; D050197:Atherosclerosis / Q000453:epidemiology; D000077407:Cilostazol; D000077144:Clopidogrel; D015897:Comorbidity; D003925:Diabetic Angiopathies / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007383:Intermittent Claudication / Q000188:drug therapy / Q000453:epidemiology; D010431:Pentoxifylline / Q000008:administration & dosage; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D013777:Tetrazoles / Q000008:administration & dosage; D015912:Thrombolytic Therapy; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D013777:Tetrazoles; D000077144:Clopidogrel; D000077407:Cilostazol; D013988:Ticlopidine; D001241:Aspirin; D010431:Pentoxifylline