title: Multiple primary primitive neuroectodermal tumours within the spinal epidural space with non-concurrent onset.
abstract: A case of multiple primary primitive neuroectodermal tumours (PNETs), which occurred at different levels of the spinal epidural space successively over a period of 8 months, is reported. A 24-year-old male, presenting with rapidly progressive paralysis, hyperthesia and a posterior epidural mass extending from T8 to T10 revealed by magnetic resonance imaging (MRI), exhibited a good recovery after initial emergency surgery. Lower back pain, chest pain and paralysis were subsequently reported. Spinal MRI in month 7 revealed a mass extending from T12 to L1 and another mass extending from T4 to T5 was detected epidurally in month 8. Additional operations were performed and radiotherapy was given. Pathological findings were consistent with PNETs and symptoms improved with treatment, particularly following each surgical excision.
authors.affiliation: Department of Neurosurgery, Renji Hospital, Shanghai Jiaotong University/School of Medicine, Shanghai, People's Republic of China.
authors.forename: J F
authors.initials: JF
authors.lastname: Feng
authors.forename: Y M
authors.initials: YM
authors.lastname: Liang
authors.forename: Y H
authors.initials: YH
authors.lastname: Bao
authors.forename: Y H
authors.initials: YH
authors.lastname: Pan
authors.forename: J Y
authors.initials: JY
authors.lastname: Jiang
mesh_terms: D000328:Adult; D001416:Back Pain / Q000209:etiology; D003937:Diagnosis, Differential; D019583:Dose Fractionation, Radiation; D004824:Epidural Space / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D011879:Radiotherapy Dosage; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery