[Familial exudative vitreoretinopathy associated with persistence of hyaloid artery].
Familial exudative vitreoretinopathy (FEVR) is a well-defined inherited disorder of retinal vessel development. Association of FEVR with other congenital ocular diseases has already been described. We report the first clinical case of FEVR associated with hyaloid artery persistence. An 18-year-old Tunisian woman and four members of her family (mother, two brothers, and sister) presented signs of FEVR. Examination of this patient also revealed functional hyaloid artery persistence in her right eye. These two disorders have many common aspects in their pathological process, in particular vascular endothelial growth factor expression, which can explain this association.
Errais
K
K
Service d'Ophtalmologie de l'hôpital Charles Nicolle, Tunis, Tunisie.
Ammous
I
I
Kamoun
R
R
Mili Boussen
I
I
Anene
R
R
Zhioua
R
R
Meddeb Ouertani
A
A
D000328:Adult; D015785:Eye Diseases, Hereditary / Q000235:genetics* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009389:Neovascularization, Pathologic / Q000235:genetics* / Q000601:surgery; D009679:Nuclear Family; D009880:Ophthalmic Artery / Q000002:abnormalities / Q000473:pathology; D010375:Pedigree; D012163:Retinal Detachment / Q000235:genetics*; D012171:Retinal Vessels / Q000473:pathology; D014821:Vitrectomy; D018630:Vitreoretinopathy, Proliferative / Q000235:genetics* / Q000601:surgery; D014822:Vitreous Body / Q000473:pathology