title: Stereoselective synthesis of (+)-polyoxamic acid based on the synthesis of chiral oxazine.
abstract: A concise, stereocontrolled synthesis of (+)-polyoxamic acid was achieved. Starting from trans-oxazoline as a chiral building block, the key step involves diastereoselective oxazine formation catalyzed by palladium(0).
authors.affiliation: College of Pharmacy, SungKyunKwan University, Suwon, 440-746, Korea.
authors.forename: Jae-Eun
authors.initials: JE
authors.lastname: Joo
authors.forename: Van-Thoai
authors.initials: VT
authors.lastname: Pham
authors.forename: Yong-Shou
authors.initials: YS
authors.lastname: Tian
authors.forename: Yun-Sung
authors.initials: YS
authors.lastname: Chung
authors.forename: Chang-Young
authors.initials: CY
authors.lastname: Oh
authors.forename: Kee-Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Won-Hun
authors.initials: WH
authors.lastname: Ham
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013400:Sugar Acids / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000596:Amino Acids; D010078:Oxazines; D013400:Sugar Acids; C529752:polyoxamic acid