Is mucociliary transport velocity related to symptoms in chronic rhinosinusitis patients?
Mucociliary transport velocity (MTV) measured by rhinoscintigraphy is considered a reliable measure of mucociliary clearance, one of the mechanisms that are distorted in chronic rhinosinusitis (CRS). The aim of this study was to investigate possible correlation of MTV with the severity of patients' symptoms. We have studied thirty-seven CRS patients who completed the 20-item sinonasal outcome test (SNOT-20) form, a reliable measure of health related quality of life and were also examined by rhinoscintigraphy with technetium-99m macroaggregated albumin. Our findings showed that the MTV of our patients ranged from nil to 4.17mm/min with a mean value of 1.74+/-1.055 mm/min. The SNOT-20 scores varied from 0.3 to 3.7 with a mean of 1.6+/-0.922. The correlation between SNOT-20 score and MTV was not statistically significant (Spearman's r=-0.191). In conclusion, although rhinoscintigraphy is widely accepted as a reliable test of mucociliary velocity and clearance, it did not correlate with subjective measures of the severity of CRS.
Athanasopoulos
Ioannis
I
Department of Otolaryngology, Head and Neck Surgery, Agia Sophia Children's Hospital, Athens, Greece. athanasopoulosj@hotmail.com
Naxakis
Stefanos
S
Vlastos
Ioannis M
IM
Mastronikolis
Nicholas S
NS
Giannakenas
Costas
C
Vassilakos
Pavlos
P
Goumas
Panos
P
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance; D009093:Mucus / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012220:Rhinitis / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D012709:Serum Albumin; D012852:Sinusitis / Q000000981:diagnostic imaging*; D013223:Statistics as Topic; D013668:Technetium Tc 99m Aggregated Albumin; D017971:Tin Compounds
D019275:Radiopharmaceuticals; D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D017971:Tin Compounds; C038216:technetium Tc 99m-Sn aggregated albumin