In vivo Investigation of Hypothalamic Secretory Activity.
The finding that all pituitary hormones are released in a discrete pulsatile fashion and that the pulsatile properties of the pituitary hormone secretion are altered in some physiologic and pathologic conditions prompted the development of techniques designed to study the pattern of release and the regulation of secretion of the hypothalamic neuropeptides. This review describes the currently used techniques to assess hypothalamic hormone secretion. (Trends Endocrinol Metab 1997;8:105-111). (c) 1997, Elsevier Science Inc.
Barkan
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Division of Endocrinology and Metabolism, the Departments of Internal Medicine and Pediatrics, and the Reproductive Sciences Program, University of Michigan Medical Center, Ann Arbor, MI 48109-0354; and the Department of Veterans Affairs Medical Center, Ann Arbor, Michigan 48105USA.
Jaffe
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Padmanabhan
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