[Epileptic seizure and migraine visual aura: revisiting migralepsy].
BACKGROUND
The term of "migralepsy" has been proposed to define migraine-triggered epileptic seizures. Although already reported in the literature for more than fifty years, a number of observations remain debatable because of possible confusion between migraine and epileptic seizure clinical manifestations, including hemifield visual hallucinations, digestive signs and severe headache.


METHODS
We report on the case of a young patient suffering from both diseases, in whom a visual aura preceded either migraine attacks or epileptic generalized tonic-clonic seizure. Subtle modification in the primitive visual hallucination, which suddenly contained colored figures and was accompanied by fear before a prolonged loss of contact, suggested a continuum between migraine aura and epileptic seizure in this patient. Brain MRI was normal and EEG showed some sharp waves in the right posterior area.


CONCLUSIONS
The presence of a neurophysiological continuum between migrainous aura and epileptic seizure is supported by this observation of "migralepsy". Recent findings from genetic and epidemiological studies further support this link.
Barré
M
M
Unité épilepsie et malaises neurologiques, département de neurologie, CHU de Grenoble, B.P. 217, 38043 Grenoble, France.
Hamelin
S
S
Minotti
L
L
Kahane
P
P
Vercueil
L
L
D000293:Adolescent; D001921:Brain / Q000473:pathology; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology*; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005239:Fear; D006212:Hallucinations / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020325:Migraine with Aura / Q000150:complications*; D012640:Seizures / Q000209:etiology*; D014794:Visual Fields