title: Retinal sensitivity measured with the micro perimeter 1 after resolution of central serous chorioretinopathy.
abstract: OBJECTIVE
  To examine retinal sensitivity in the macular area of eyes with resolved central serous chorioretinopathy (CSC).
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  We studied retrospectively the medical records of 21 patients (21 eyes) with resolved CSC. Using spectral-domain optical coherence tomography (SD-OCT), 6 x 6-mm areas of macula were examined with 256 sequential horizontal scans. Microperimetry in the macular area was performed with the Micro Perimeter 1 (Nidek, Vigonza, Italy). Seventy-two measurement points were located within the central 10 degrees of the macula.
  
  
  RESULTS
  In eyes with resolved CSC, most OCT images showed a physiologically normal appearance. However, irregularities of the retinal pigment epithelium (RPE) were detected in 11 eyes, and focal defects of the junctions between inner and outer segments (IS/OS) of the photoreceptors were noted in 15 eyes. These abnormalities often were seen within the foveal region. At 983 (79.8%) of 1,232 points with intact retina, retinal sensitivity was 16 decibels (dB) or better. However, a retinal sensitivity of 16 dB or better was obtained at 34.0% of points with irregular RPE and in 20.0% of points with defects of the IS/OS. The mean retinal sensitivities within the area with irregular RPE (13.4 +/- 4.8 dB) or with defects of the IS/OS (11.5 +/- 4.2 dB) were significantly lower than that of intact retina (17.5 +/- 2.4 dB; P < .0001).
  
  
  CONCLUSIONS
  Eyes with resolved CSC often show focal areas with reduced retinal function, which are consistent with irregularity of the RPE or with defects of the IS/OS.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, Japan.
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Ojima
authors.forename: Akitaka
authors.initials: A
authors.lastname: Tsujikawa
authors.forename: Masanori
authors.initials: M
authors.lastname: Hangai
authors.forename: Hideo
authors.initials: H
authors.lastname: Nakanishi
authors.forename: Ryo
authors.initials: R
authors.lastname: Inoue
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sakamoto
authors.forename: Nagahisa
authors.initials: N
authors.lastname: Yoshimura
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology / Q000503:physiopathology*; D012160:Retina / Q000503:physiopathology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D012189:Retrospective Studies; D044967:Serum; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests / Q000379:methods*