[Biological monitoring in workers exposed to inorganic arsenic in a disused industrial plant in the area of Manfredonia].
Inorganic arsenic and its methylated metabolities were measured in 108 spot urine samples obtained from the medical surveillance programme of workers exposed to inorganic Arsenic in July 2006. 15% of the samples showed levels higher than limit value of 35 microg/L (mean value 23,9 microg/L). After the improvement of the working conditions, in August-October 2006, we collected a urinary sample from each of the 108 workers enrolled. A questionnaire was also administrated, in order to investigate the influence of occupational and non occupational factors on the urinary arsenic excretion. The median value of urinary arsenic was 15,12 microg/L; among the 108 samples, 5% showed levels higher than limit value. A significant difference was observed in relation with sea-food consumption and aging stratification. In conclusion, we have described a significant reduction of urinary arsenic excretion between the two phases of biological monitoring, likely due to a proper hygienic work-related intervention.
Vimercati
L
L
Dipartimento di Medicina Interna e Medicina Pubblica, Sezione di Medicina del Lavoro B. Ramazzini, Facoltà di Medicina e Chirurgia, Università degli Studi di Bari, Policlinico, Piazza G. Cesare 11, 70124 Bari. l.vimercati@medlav.uniba.it
Carrus
A
A
Gagliardi
T
T
Sciannamblo
G
G
Caputo
F
F
Minunni
V
V
Bellotta
M R
MR
de Nichilo
G
G
Bisceglia
L
L
Corrado
V
V
De Pasquale
P
P
Assennato
G
G
D001151:Arsenic / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D004784:Environmental Monitoring; D006801:Humans; D007221:Industry; D007558:Italy; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016272:Occupational Health; D011159:Population Surveillance
D015415:Biomarkers; D001151:Arsenic