title: [Determination of bisphenol A and alkyl phenols in canned food with high performance liquid chromatography--fluorescence].
abstract: OBJECTIVE
  To establish a comprehensive analytical high performance liquid chromatography fluorescence detection (HPLC-FL) in detecting bisphenol A (BPA), nonylphenol (NP) and octylphenol (OP) in canned food sold in Beijing markets.
  
  
  METHODS
  BPA, NP and OP was extracted with methanol and dichloroacetamide and concentrated. The samples were purified on an solid extraction cartridges. The HPLC system consisted of Waters XTerra MS C18 column, a mixture of methanol and water as mobile phase and fluorescence detector with the excitation and emission wavelength at 225 nm and 310 nm respectively.
  
  
  RESULTS
  The method established had a linear relationship, showing the detection limit of BPA, OP and NP being 0.5, 0.1 and 0.1 microg/kg in canned vegetable and instant noodle and 1, 0.5 and 0.5 microg/kg in canned fish and meat can, respectively. The recoveries of BPA, NP and OP were 74.9%-95.1% , 76.3%-103.6% and 72.1%-109.2%. The precision was 4.98%-11.2% , 2.35%-8.88% and 5.61%-12.3%, respectively.
  
  
  CONCLUSIONS
  The method is simple with high sensitivity and selectivity, suitable for the determination of NP, OP and BPA in canned food.
authors.affiliation: National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Xiao
authors.forename: Bing
authors.initials: B
authors.lastname: Shao
authors.forename: Yong-Ning
authors.initials: YN
authors.lastname: Wu
authors.forename: Zhu-Tian
authors.initials: ZT
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Hou
mesh_terms: D001559:Benzhydryl Compounds; D002851:Chromatography, High Pressure Liquid; D005513:Food Inspection / Q000379:methods*; D010636:Phenols / Q000032:analysis*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; C474055:octylphenol; C025256:nonylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds