Polypoid eosinophilic cystitis with pseudosarcomatous proliferative tissue in a dog.
A dog presented with hematuria, and two small polypoid masses were detected in the urinary bladder. Histopathologically, the masses were located in the mucosal or submucosal layer. That tissue consisted of a random proliferation of spindle-shaped, round and pleomorphic cells with single or multiple large atypical nuclei and abundant cytoplasm, and eosinophil infiltration. These large cells were confirmed by immunohistochemical staining as fibroblasts, myofibroblasts and macrophages. Mitotic figure was rarely seen. These masses were diagnosed as eosinophilic polypoid cystitis with pseudosarcomatous proliferative tissue, since they consisted of a wide variety of cells and showed low growth activity.
Ozaki
Kiyokazu
K
Department of Pathology, Faculty of Pharmaceutical Science, Setsunan University, Hirakata, Osaka, Japan. ozaki@pharm.setsunan.ac.jp
Nakahara
Yutaka
Y
Narama
Isao
I
D000818:Animals; D003239:Connective Tissue Cells / Q000473:pathology; D003556:Cystitis / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D006417:Hematuria / Q000209:etiology / Q000662:veterinary*; D007150:Immunohistochemistry