title: [Retrospective study on clinical application of biovalves in 52 cases].
abstract: OBJECTIVE
  To summarize the clinical application of bioprosthetic valve replacement.
  
  
  METHODS
  Fifty two patients, aged 13-73(52.4+/-14.0) years, underwent cardiac valve replacement with biovalves from June 2002 to June 2006 in our hospital. Fifty three tissue valve replacements combined with 8 mechanical valve replacements were performed. Other procedures were also carried out if appropriate, including bidirectional Glenn shunt in 1 patient with double outlet of right ventricle and pulmonary artery stenosis; interruption of accessory pathway in 1 patient with Wolff-Parkinson-White syndrome; coronary artery bypass graft in 5 with severe coronary artery disease; and atrial or ventricular repair in 4 with congenital septum defects.
  
  
  RESULTS
  One patient died in hospital due to multiple organ failure. The hospital mortality rate was 1.9%. The mean follow-up was 25 months. Two patients lost follow-up and the follow-up rate was 96%. Forty one patients returned to NYHA class I, 9 to class II, and 1 to class III. Echocardiography showed the implanted bioprosthesis functioned well without stenosis or regurgitation. There was no structural deterioration with freedom from thromboembolism and anticoagulant hemorrhage in all patients.
  
  
  CONCLUSIONS
  The efficacy of biovalves in heart valve replacement is satisfactory.
authors.affiliation: Department of Cardiothoracic Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.forename: Jian-guo
authors.initials: JG
authors.lastname: Hu
authors.forename: Bang-liang
authors.initials: BL
authors.lastname: Yin
authors.forename: Jin-fu
authors.initials: JF
authors.lastname: Yang
authors.forename: Tao
authors.initials: T
authors.lastname: Tang
authors.forename: Hua
authors.initials: H
authors.lastname: Gao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001705:Bioprosthesis; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D012189:Retrospective Studies; D014261:Tricuspid Valve / Q000601:surgery