title: Sesquiterpene lactones from Staehelina fruticosa.
abstract: The phytochemical analysis of Staehelina fruticosa led to the isolation of four germacranolide-type sesquiterpene lactones (1- 4), including two new glycosides. The structures of these sesquiterpene lactones were elucidated using spectroscopic techniques, and enzymatic hydrolysis was carried out to confirm the nature of the two glycoside derivatives. Molecular modeling was incorporated to substantiate their relative configuration.
authors.affiliation: Division of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, Greece. skaltsounis@pharm.uoa.gr
authors.forename: Maria P
authors.initials: MP
authors.lastname: Kotsos
authors.forename: Nektarios
authors.initials: N
authors.lastname: Aligiannis
authors.forename: Vasillios
authors.initials: V
authors.lastname: Myrianthopoulos
authors.forename: Sofia
authors.initials: S
authors.lastname: Mitaku
authors.forename: Leandros
authors.initials: L
authors.lastname: Skaltsounis
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D006115:Greece; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D045788:Sesquiterpenes, Germacrane / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D007783:Lactones; D045788:Sesquiterpenes, Germacrane; C432449:germacranolide