Experimental validation for the use of a film on the basis of modified hyaluronic acid for prevention of postoperative peritoneal adhesions.
A film coating based on hyaluronic acid and 5-aminosalicylic acid was developed for the creation of anti-adhesion barrier. Application of the protective film in Wistar rats with modeled adhesion process in the abdominal cavity reduced the formation of peritoneal adhesions.
Sufiyarov
I F
IF
Bashkir State Medical University, Russian Ministry of Health. ildars@ufanet.ru
D000818:Animals; D001672:Biocompatible Materials; D006820:Hyaluronic Acid; D008422:Materials Testing; D019804:Mesalamine; D010532:Peritoneal Diseases / Q000473:pathology / Q000517:prevention & control*; D010537:Peritoneum / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D051381:Rats; D017208:Rats, Wistar; D000267:Tissue Adhesions / Q000473:pathology / Q000517:prevention & control*
D001672:Biocompatible Materials; D019804:Mesalamine; D006820:Hyaluronic Acid