title: Synthesis of (2-oxoindolin-3-ylidene)methyl acetates involving a C-H functionalization process.
abstract: A novel palladium-catalyzed oxidative C-H functionalization protocol for the synthesis of (2-oxoindolin-3-ylidene)methyl acetates has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, a variety of N-arylpropiolamides underwent the C-H functionalization reaction with acids to afford the corresponding (E)-(2-oxoindolin-3-ylidene)methyl acetates selectively in moderate to excellent yields.
authors.affiliation: College of Chemistry and Materials Science, Wenzhou University, Wenzhou, China.
authors.forename: Shi
authors.initials: S
authors.lastname: Tang
authors.forename: Peng
authors.initials: P
authors.lastname: Peng
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Wang
authors.forename: Bo-Xiao
authors.initials: BX
authors.lastname: Tang
authors.forename: Chen-Liang
authors.initials: CL
authors.lastname: Deng
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Zhong
authors.forename: Nai-Xing
authors.initials: NX
authors.lastname: Wang
mesh_terms: D000085:Acetates / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry*
chemical_list: D000085:Acetates; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D010165:Palladium; C046923:methyl acetate