Antioxidative compounds from Quercus salicina Blume stem.
The chromatographic separation of MeOH extract from the Quercus salicina Blume Stem led to the isolation of five phenolic compounds. Using spectroscopic methods, the structures of these compounds were determined as D-threo-guaiacylglycerol 8-O-beta-D-(6'-O-galloyl)glucopyranoside (1), 9-methoxy-D-threo-guaiacylglycerol 8-O-beta-D-(6'-O-galloyl)glucopyranoside (2), 6''-O-galloyl salidroside (3), methyl gallate (4), quercetin (5). We measured radical scavenging activity with the DPPH method and the anti-lipid peroxidative efficacy on human LDL with TBARS assay, with the result that all these compounds exhibited the antioxidative activity.
Kim
Jung-Il
JI
College of Pharmacy, Chung-Ang University, 221 Huekseok-Dong Dongjak-Gu, Seoul 156-756, Korea.
Kim
Ho-Hyun
HH
Kim
Sungun
S
Lee
Kyoung-Tae
KT
Ham
In-Hye
IH
Whang
Wan-Kyunn
WK
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001713:Biphenyl Compounds; D002845:Chromatography; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D005960:Glucosides / Q000494:pharmacology; D005990:Glycerol / Q000031:analogs & derivatives / Q000494:pharmacology; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008077:Lipoproteins, LDL / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates / Q000737:chemistry; D018547:Plant Stems; D011794:Quercetin / Q000494:pharmacology; D029963:Quercus / Q000737:chemistry; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D008077:Lipoproteins, LDL; D010851:Picrates; D017392:Thiobarbituric Acid Reactive Substances; C099252:oxidized low density lipoprotein; C052082:methyl gallate; D005707:Gallic Acid; D011794:Quercetin; C004931:1,1-diphenyl-2-picrylhydrazyl; D005990:Glycerol