Recurrence of cholangiogenous carcinoma in port-sites two years after laparoscopic removal of noncancerous gallbladder.
We present a unique case of carcinoma diagnosed in port-site, two years after uncomplicated laparoscopic cholecystectomy for benign cholecystitis. Analysis of morphology and cytokeratin profile (CK19+ and CK20+/-) of resected port-site tumor allows us to establish the diagnosis of tubular carcinoma with probable cholangiogenic origin. The primary carcinoma was not diagnosed in archival gallbladder tissue, despite repeated histological examination. No other primary tumor was identified during follow-up. Patient history and histological/immunohistochemical picture of the recurrent tumor suggested that primary carcinoma was probably located in the gallbladder, but was not detected during initial and repeated histological examinations of postoperative specimen. The patient is still alive, 12 months after the first port-site recurrence and 36 months after initial laparoscopy.
Piekarski
Janusz H
JH
Department of Surgical Oncology, Medical University of Lodz, Lodz, Poland. januszpiekar@poczta.onet.pl
Kusinska
Renata
R
Nejc
Dariusz
D
Pluta
Piotr
P
Sek
Piotr
P
Bilski
Adam
A
Durczynski
Adam
A
Kubiak
Robert
R
Pasz-Walczak
Grazyna
G
Jeziorski
Arkadiusz
A
D034861:Abdominal Wall; D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D002764:Cholecystitis / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009366:Neoplasm Seeding; D009382:Neoplasms, Unknown Primary