(1)H MR spectroscopy of human brain tumours: a practical approach.
Magnetic resonance spectroscopy (MRS) is proposed in addition to magnetic resonance imaging (MRI) to help in the characterization of brain tumours by detecting metabolic alterations that may be indicative of the tumour class. MRS can be routinely performed on clinical magnets, within a reasonable acquisition time and if performed under adequate conditions, MRS is reproducible and thus can be used for longitudinal follow-up of treatment. MRS can also be performed in clinical practice to guide the neurosurgeon into the most aggressive part of the lesions or to avoid unnecessary surgery, which may furthermore decrease the risk of surgical morbidity.
Callot
Virginie
V
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France. Electronic address: virginie.callot@univmed.fr.
Galanaud
Damien
D
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France; Département de Neuroradiologie, Hôpital La Pitié-Salpêtrière, Paris, France.
Le Fur
Yann
Y
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France.
Confort-Gouny
Sylviane
S
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France.
Ranjeva
Jean-Philippe
JP
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France.
Cozzone
Patrick J
PJ
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS - Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France.
D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*