title: Comparison of 60cobalt and 192iridium sources in high dose rate afterloading brachytherapy.
abstract: OBJECTIVE
  (60)Co sources with dimensions identical to those of (192)Ir have recently been made available in clinical brachytherapy. A longer half time reduces demands on logistics and quality assurance and perhaps costs.
  
  
  METHODS
  Comparison of the physical properties of (60)Co and (192)Ir with regard to brachytherapy.
  
  
  RESULTS
  Required activities for the same air kerma rate are lower by a factor of 2.8 for (60)Co. Differential absorption in tissues of different densities can be neglected. Monte Carlo calculations demonstrate that integral dose due to radial dose fall off is higher for (192)Ir in comparison to (60)Co within the first 22 cm from the source (normalization at 1 cm). At larger distances this relationship is reversed.
  
  
  CONCLUSIONS
  Clinical examples for intracavitary and interstitial applications however, show practically identical dose distributions in the treatment volume.
authors.affiliation: Department of Radiation Oncology, Julius Maximilians University of Wuerzburg, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Richter
authors.forename: Kurt
authors.initials: K
authors.lastname: Baier
authors.forename: Michael
authors.initials: M
authors.lastname: Flentje
mesh_terms: D001610:Beta Particles / Q000627:therapeutic use; D001918:Brachytherapy / Q000379:methods*; D003037:Cobalt Radioisotopes / Q000191:economics / Q000627:therapeutic use*; D003365:Costs and Cost Analysis; D006801:Humans; D007496:Iridium Radioisotopes / Q000191:economics / Q000627:therapeutic use*; D007700:Kinetics; D009369:Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage
chemical_list: D003037:Cobalt Radioisotopes; D007496:Iridium Radioisotopes