title: Capsaicin inhibits proliferation of endometriotic cells in vitro.
abstract: Treatment of immortalized stromal-like and epithelial-like endometriotic cells with capsaicin resulted in inhibition of proliferation in a concentration-dependent manner. In addition, endometriotic cells are more sensitive to capsaicin treatment than immortalized endometrial cells, suggesting that capsaicin may be an admissible drug candidate for treating endometriosis.
authors.affiliation: Taussig Cancer Center, Center for Hematology and Oncology Molecular Therapeutics, Cleveland, Ohio, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wu
authors.forename: Anna
authors.initials: A
authors.lastname: Starzinski-Powitz
authors.forename: Sun-Wei
authors.initials: SW
authors.lastname: Guo
mesh_terms: D002211:Capsaicin / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004715:Endometriosis / Q000473:pathology*; D004717:Endometrium / Q000187:drug effects* / Q000473:pathology*; D005260:Female; D006131:Growth Inhibitors / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques
chemical_list: D006131:Growth Inhibitors; D002211:Capsaicin