title: Bilateral pulmonary artery banding for hypoplastic left heart syndrome and related anomalies.
abstract: OBJECTIVE
  Bilateral pulmonary artery banding is considered an option for initial palliation in high-risk patients with hypoplastic left heart syndrome or related anomalies. However, there are potential interim morbidities, including ductal constriction, compromised growth of the ascending aorta, and pulmonary artery stenosis at the banding site. In addition, there are still controversies regarding the optimal timing and choice of the second-stage operation.
  
  
  METHODS
  Between February 2003 and October 2005, twelve high-risk patients with hypoplastic left heart syndrome or related anomalies underwent bilateral pulmonary artery banding. An atrial septal defect was created simultaneously when the septum was intact or the defect was restrictive. After the procedure, intravenous prostaglandin E(1) was continuously administered.
  
  
  RESULTS
  The median weight was 3.0 kg (range 1.8-3.6 kg), and the median age was 16 days (range 0-27 days). Atrial septum defect creation was performed simultaneously in two patients. Ten of the twelve patients were discharged from the hospital. One patient died of progressive multiple organ failure and another patient died of cerebral hemorrhage. Eight patients developed various degrees of ductal constriction and required dose adjustment of prostaglandin E(1). Two patients underwent ductal arteriosus stent placement: one was unsuccessful owing to the size mismatch between the stent and the ductus. The diameter of the ascending aorta remained unchanged until the time of the second-stage operation, except in two patients who had a sufficiently sized aorta at the time of pulmonary artery banding. Pulmonary arterial branch stenosis developed at the banding site in three patients. At the time of the second-stage operation, the Norwood procedure was performed in seven patients, biventricular repair in two, and Norwood plus Glenn procedure in one.
  
  
  CONCLUSIONS
  Bilateral pulmonary artery banding is an option to salvage high-risk neonates with hypoplastic left heart syndrome or related anomalies. However, it is associated with high interstage morbidity, and patients may benefit from early conversion to the Norwood operation.
authors.affiliation: Department of Pediatric Cardiac Surgery, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, Tokyo, 183-0003, Japan. tsasakister@gmail.com
authors.forename: Takashi
authors.initials: T
authors.lastname: Sasaki
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Ando
authors.forename: Naoki
authors.initials: N
authors.lastname: Wada
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kawase
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Seki
mesh_terms: D001011:Aorta / Q000254:growth & development; D006348:Cardiac Surgical Procedures; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D007231:Infant, Newborn; D008026:Ligation; D010166:Palliative Care; D011183:Postoperative Complications; D011651:Pulmonary Artery / Q000601:surgery*; D012307:Risk Factors; D015996:Survival Rate