title: [Results of administering Phlebodia 600 in fertile women with orthostasis-dependent phlebopathy].
abstract: Presented herein are the findings of a prospective, non-comparative study of the clinical efficacy of semisynthetic diosmine (preparation Phlebodia 600) in patients presenting withCEAP class 0-1 chronic venous insufficiency (CVI) manifesting itself as orthostasis-dependent phlebopathy. Based on a total of 67 case reports, it was shown that Phlebodia 600 exerted a positive effect on the functional symptoms of CVI, oedematic and convulsive syndromes. A conclusion was made of a high efficacy and safety of the drug in treatment of initial-grade CVI in fertile women with orthostasis-dependent phlebopathy, including hormone-induced variants. Noted was positive dynamics of the preparation with the necessity of continuing to take oral contraceptives by the medical indications.
authors.forename: Iu T
authors.initials: IuT
authors.lastname: Tsukanov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Tsukanov
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001783:Blood Flow Velocity; D004145:Diosmin / Q000008:administration & dosage*; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010991:Plethysmography; D011187:Posture; D011446:Prospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014654:Vascular Patency; D014689:Venous Insufficiency / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
chemical_list: D004145:Diosmin