title: Effects of active egg white product/ Clostridium butyricum Miyairi 588 additive on peripheral leukocyte populations in periparturient dairy cows.
abstract: The leukocyte populations of periparturient dairy cows were analyzed after administration of active egg white/Clostridium butyricum Miyairi additive. Sixty-eight Holstein milking cows were divided into 3 groups. Group A was administered active egg white product (AEWP)/Clostridium butyricum Miyairi 588 (Miyairi 588) additive (n=23). Group B was administered Miyairi 588 only (n=23), and Group C was the control group (n=22). The challenged groups were administered 100 g of AEWP + Miyairi 588, or Miyairi 588 alone, daily for 60 days from 1 month before until 1 month after paturition. Blood samples were collected from all groups three times (1 month before, 1 week after and 1 month after parturition) for analysis of the peripheral leukocyte population. The results showed significantly higher numbers of CD4+ cells in Group A compared with Group C 1 week after paturition. AEWP/Miyairi 588 additive may enhance the number of CD4+ T cells in periparturient dairy cows.
authors.affiliation: Kohiruimaki Animal Medical Service, Tohoku, Aomori, Japan. kopi@kopi-kopi.com
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kohiruimaki
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Ohtsuka
authors.forename: Erika
authors.initials: E
authors.lastname: Tanami
authors.forename: Madoka
authors.initials: M
authors.lastname: Kitagawa
authors.forename: Machiko
authors.initials: M
authors.lastname: Masui
authors.forename: Takaaki
authors.initials: T
authors.lastname: Ando
authors.forename: Seiichi
authors.initials: S
authors.lastname: Kawamura
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000284:Administration, Oral; D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000517:prevention & control*; D046972:Clostridium butyricum / Q000276:immunology*; D004529:Egg White; D005260:Female; D005434:Flow Cytometry
chemical_list: D000276:Adjuvants, Immunologic