title: Hexaquacobalt(II) bis(5-hydroxy-7-methoxy-4-oxo-2-phenyl-4H-chromene-6-sulfonate) tetrahydrate.
abstract: The title compound, [Co(H(2)O)(6)](C(16)H(11)O(7)S)(2) x 4 H(2)O, with cobalt(II) at the centre of symmetry, exhibits alternating hydrophilic and hydrophobic regions. Hydrophilic regions are generated by O-H...O hydrogen bonds among sulfonate groups, involving solvent water molecules and coordinated water molecules; pi-pi stacking interactions assemble the flavone skeletons into columns which form the hydrophobic regions. A three-dimensional network is built up from an extensive array of hydrogen bonds, pi-pi stacking interactions and electrostatic interactions between the cation and anion. As a salt of the sulfonated derivative of naturally occurring tectochrysin (5-hydroxy-7-methoxyflavone), this compound offers enhanced solubility and potential biological activity over the natural product.
authors.affiliation: Key Laboratory of Medicinal Plant Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), Ministry of Education, Xi'an 710062, People's Republic of China.
authors.forename: Wu-Wu
authors.initials: WW
authors.lastname: Li
authors.forename: Zun-Ting
authors.initials: ZT
authors.lastname: Zhang
mesh_terms: D003035:Cobalt / Q000737:chemistry*; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D012995:Solubility; D013055:Spectrophotometry, Infrared; D055672:Static Electricity
chemical_list: D003035:Cobalt