title: Pseudallescheria boydii or Aspergillus fumigatus in a lady with an unresolving lung infiltrate, and a literature review.
abstract: A 53-year-old lady with blood-stained sputum and pleuritic pain had a lingular opacity on CXR which failed to resolve. A bronchial aspirate and transbronchial biopsy revealed features of bronchocentric granulomatosis with dichotomous branching hyphae suggestive of Aspergillus infection. However, subsequent fungal culture grew Pseudallescheria boydii. This case demonstrates the similarity of clinical and histological features caused by these two fungi. This appears to be the first reported case of pulmonary pseudallescheria with a bronchocentric granulomatous response.
authors.affiliation: Division of Respiratory and Critical Care Medicine, Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China. gsmlam@gmail.com
authors.forename: Sin-Man
authors.initials: SM
authors.lastname: Lam
authors.forename: Arthur Chun-Wing
authors.initials: AC
authors.lastname: Lau
authors.forename: Ming-Wai
authors.initials: MW
authors.lastname: Ma
authors.forename: Loretta Yin-Chun
authors.initials: LY
authors.lastname: Yam
mesh_terms: D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D001232:Aspergillus fumigatus / Q000302:isolation & purification* / Q000472:pathogenicity; D005260:Female; D006801:Humans; D008168:Lung / Q000382:microbiology* / Q000473:pathology; D008875:Middle Aged; D008271:Mycetoma / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D011541:Pseudallescheria / Q000302:isolation & purification* / Q000472:pathogenicity