title: Acute kidney injury with iodinated contrast.
abstract: Diagnostic and interventional radiographic procedures in critically ill patients commonly depend on iodinated contrast media and consequently pose the risk of contrast-induced acute kidney injury. This is an important complication that accounts for a significant number of cases of hospital-acquired renal failure, with adverse effects on prognosis and healthcare costs. The epidemiology and pathogenesis of contrast-induced acute kidney injury, baseline renal function measurement, risk assessment, identification of high-risk patients, contrast medium use, and preventive strategies will be discussed in this article. An algorithm is suggested for the risk stratification and management of contrast-induced acute kidney injury as it relates to patients undergoing iodinated contrast exposure during critical illness. Contrast-induced acute kidney injury is likely to remain a significant challenge for intensivists in the future because the patient population is aging and chronic kidney disease and diabetes are becoming more common.
authors.affiliation: Division of Cardiology, William Beaumont Hospital, Royal Oak, MI, USA. pmc975@yahoo.com
authors.forename: Peter A
authors.initials: PA
authors.lastname: McCullough
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000191:economics / Q000503:physiopathology; D003287:Contrast Media / Q000009:adverse effects*; D017048:Health Care Costs; D006801:Humans; D015994:Incidence; D011379:Prognosis; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D003287:Contrast Media