[The role of nitric oxide (NO) in acute pancreatitis].
The hypothesis of the role of nitric oxide (NO) in acute pancreatitis (AP) is variable. According to some authors, increased level of nitric oxide has a positive influence on the course of AP. On the other hands, others show negative role of NO in this disease. NO plays many different roles in the organism. It regulates blood pressure, relaxes smooth muscle, plays a role in neurotransmition (for instance in specific and nonspecific immunological responses). NO regulates microcirculation within the pancreas and has an impact on the clinical courses of the mild as well as severe forms of the disease. It is also produced in the lungs alveoli and it is partly responsible for pulmonary complications of AP.
Panek
Józefa
J
II Katedra Chirurgii Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków. mspanek@cyf-kr.edu.pl
Zasada
Jakub
J
D000208:Acute Disease; D006801:Humans; D008168:Lung / Q000378:metabolism*; D008833:Microcirculation; D009504:Neutrophils / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism*; D010179:Pancreas / Q000098:blood supply*; D010195:Pancreatitis / Q000378:metabolism*
D009569:Nitric Oxide