title: The use of stem cells in the treatment of inoperable limb ischemia.
abstract: Autologous stem cell-based therapy offers many advantages over other nonsurgical treatments of peripheral arterial disease. Transplant stem cells are a renewable source of multiple cytokines and growth factors. Autologous adult stem cells are not rejected and do not form teratomas. Early preliminary results indicate that adult stem cell therapy is safe and effective in patients with critical limb ischemia.
authors.affiliation: Division of Vascular Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA. wpearce@nmh.org
authors.forename: William H
authors.initials: WH
authors.lastname: Pearce
authors.forename: Richard
authors.initials: R
authors.lastname: Burt
authors.forename: Heron E
authors.initials: HE
authors.lastname: Rodriguez
mesh_terms: D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D014182:Transplantation, Autologous
chemical_list: D016179:Granulocyte Colony-Stimulating Factor