title: Organochlorine contaminants in hair of adolescents from Iassy, Romania.
abstract: Human hair samples (n=42) from Iassy county (Eastern Romania) collected in 2002-2003 from adolescents were analyzed for hexachlorocyclohexane (HCH) isomers, p,p'-DDT and its metabolites, hexachlorobenzene (HCB), chlordane and metabolites and 5 polychlorinated biphenyl (PCB) congeners. Very low levels were found for HCB and oxychlordane (0.8 and 2.5 ng g(-1)) indicating a low usage of these pesticide formulations in the studied area. In case of HCHs, gamma-HCH isomer was measured at higher median concentrations (79 ng g(-1) hair) compared to the beta-HCH isomer (55 ng g(-1)), which generally is the most prevalent from HCHs. The DDTs profile consisted in p,p'-DDE and p,p'-DDT which levels correspond to 81% of sum DDTs. Very high median concentrations measured for p,p'-DDT (192 ng g(-1)) combined with lower values for p,p'-DDE/p,p'-DDT of 0.4 (from 0.20 to 2.0) in all hair samples suggest recent exposure to "fresh" DDT. When gender was considered, significantly higher concentrations for most of the investigated contaminants were found in girls hair compared to boys. Very high levels were found in the present study for HCHs and DDTs compared to samples from Greece, Western Europe and China. In case of PCBs, the levels found in Romanian samples were found to be in the same range compared to other previously published data.
authors.affiliation: Department of Pharmaceutical Sciences, Toxicological Center, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium. adrian.covaci@ua.ac.be
authors.forename: Adrian
authors.initials: A
authors.lastname: Covaci
authors.forename: Carmen
authors.initials: C
authors.lastname: Hura
authors.forename: Adriana
authors.initials: A
authors.lastname: Gheorghe
authors.forename: Hugo
authors.initials: H
authors.lastname: Neels
authors.forename: Alin C
authors.initials: AC
authors.lastname: Dirtu
mesh_terms: D000293:Adolescent; D006197:Hair / Q000737:chemistry*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D012383:Romania
chemical_list: D006843:Hydrocarbons, Chlorinated