[Air pollution in urban areas as a risk factor for health in the general population and in workers. Environmental and biologic monitoring of 1-3 butadiene].
Exposure to 1,3-butadiene (BD), a probable carcinogen to humans, was investigated in two groups of subjects working in a refinery plant: 28 occupationally exposed workers and 21 subjects non-occupationally exposed controls. BD in blood was higher in the exposed workers than in controls. Excretion of urinary mercapturic acids N-acetyl-S-(3,4-hydroxybutyl)-l-cysteine (MI), was not influenced by occupational exposure. The present study shows that unmetabolised BD in biological fluids, represents the biomarker of choice for assessing occupational exposure to low airborne concentrations of BD.
Fenga
C
C
Dipartimento di Medicina Sociale del Territorio, Sezione di Medicina del Lavoro, Università degli Studi di Messina.
Catania
C
C
Di Nola
C
C
Cacciola
A
A
Germanò
D
D
Costa
C
C
D000328:Adult; D000393:Air Pollutants / Q000032:analysis* / Q000378:metabolism; D002070:Butadienes / Q000032:analysis* / Q000378:metabolism; D004781:Environmental Exposure / Q000032:analysis*; D004784:Environmental Monitoring; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*; D012307:Risk Factors; D014505:Urban Population
D000393:Air Pollutants; D002070:Butadienes; C031763:1,3-butadiene