Expression of three serine protease genes from the South East Asian malaria vector, Anopheles dirus, in relation to blood feeding and parasite infection.
Three serine protease cDNA clones were isolated from Anopheles dirus, a major vector of malaria in Southeast Asia. Transcript abundance was examined following infection by Plasmodium falciparum by RT-PCR analysis. SerF3 exhibited increased transcript abundance in the whole body at 10 days post-infection with P. falciparum. All three genes are candidates for further investigation to determine their roles in mosquito immune responses.
Sriwichai
Patchara
P
Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Rongsriyam
Yupha
Y
Jariyapan
Narissara
N
Apiwathnasorn
Chamnarn
C
Sattabongkot
Jetsumon
J
Paskewitz
Susan
S
D000818:Animals; D000852:Anopheles / Q000201:enzymology / Q000235:genetics* / Q000469:parasitology*; D001483:Base Sequence; D001769:Blood; D005247:Feeding Behavior; D015870:Gene Expression; D017344:Genes, Insect; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000502:physiology*; D012697:Serine Endopeptidases / Q000235:genetics*
D012697:Serine Endopeptidases