title: Relation of bone mineral density to frequency of coronary heart disease.
abstract: Coronary angiography was performed because of chest pain in 198 patients (146 women, 52 men; mean age 66 years) who had dual-energy x-ray absorptiometry scans of the spine and left hip because of suspected osteoporosis or osteopenia. Of the 198 patients, 53 (27%) had osteoporosis, 79 (40%) had osteopenia, and 66 (33%) had normal bone mineral density (BMD). Obstructive coronary artery disease with >50% narrowing of > or =1 major coronary artery was present in 40 of 53 patients (76%) with osteoporosis, in 54 of 79 patients (68%) with osteopenia, and in 31 of 66 patients (47%) with normal BMD (p <0.005 comparing osteoporosis with normal BMD, p <0.01 comparing osteopenia with normal BMD). In conclusion, in patients who undergo coronary angiography because of chest pain, patients with osteoporosis or osteopenia have a higher prevalence of obstructive coronary artery disease than those with normal BMD.
authors.affiliation: Department of Medicine, Cardiology Division, New York Medical College, Valhalla, New York, USA.
authors.forename: Raja
authors.initials: R
authors.lastname: Varma
authors.forename: Wilbert S
authors.initials: WS
authors.lastname: Aronow
authors.forename: Yana
authors.initials: Y
authors.lastname: Basis
authors.forename: Tarundit
authors.initials: T
authors.lastname: Singh
authors.forename: Kumar
authors.initials: K
authors.lastname: Kalapatapu
authors.forename: Melvin B
authors.initials: MB
authors.lastname: Weiss
authors.forename: Anthony L
authors.initials: AL
authors.lastname: Pucillo
authors.forename: Craig E
authors.initials: CE
authors.lastname: Monsen
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000150:complications* / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D003327:Coronary Disease / Q000150:complications* / Q000000981:diagnostic imaging; D023921:Coronary Stenosis / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications* / Q000000981:diagnostic imaging; D012189:Retrospective Studies