Endoscopic ultrasonography-guided trucut biopsy for the preoperative diagnosis of peripancreatic Castleman's disease: a case report.
Castleman's disease (CD) of the pancreas/peripancreas is extremely rare. The recently introduced, endoscopic ultrasonography (EUS)-guided trucut biopsy (TCB) is a useful diagnostic modality for obtaining tissue samples from peripancreatic lesions. However, its role in diagnosing CD remains unknown. We report a case of localized, peripancreatic, hyaline-vascular CD biopsied using EUS. The pathology results were initially interpreted as an extranodal, marginal-zone B-cell lymphoma. However, polymerase chain reaction (PCR) study for the IgH gene rearrangement revealed a polyclonal pattern. We also reviewed the relevant literature. To our knowledge, this is the first illustrated report on EUS-TCB findings of CD with its pathology results of EUS-TCB mimicked a B-cell lymphoma.
Rhee
Kyoung-Hoon
KH
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
Lee
Sang-Soo
SS
Huh
Joo-Ryung
JR
D001706:Biopsy; D001707:Biopsy, Needle / Q000379:methods; D005871:Castleman Disease / Q000175:diagnosis* / Q000601:surgery*; D019160:Endosonography / Q000379:methods*; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome