title: Anticoagulant treatment of deep vein thrombosis and pulmonary embolism.
abstract: Venous thrombosis is a common disease. As the mean age of the population increases, so does the incidence of venous thromboembolism. Anticoagulant therapy is equally effective in young and older patients, and can reduce substantially the associated morbidity and mortality. When considering long-term oral anticoagulant therapy in older patients, however, careful ongoing evaluation is imperative to ensure that the risk of bleeding does not outweigh the antithrombotic benefits.
authors.affiliation: Department of Medicine, McMaster University Medical Centre, 1200 Main Street West, Room 3X28, Hamilton, Ontario L8N 3Z5, Canada.
authors.forename: Huyen
authors.initials: H
authors.lastname: Tran
authors.forename: Simon
authors.initials: S
authors.lastname: McRae
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Ginsberg
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D000990:Antithrombin III / Q000627:therapeutic use; D017984:Enoxaparin / Q000008:administration & dosage; D000077425:Fondaparinux; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D011134:Polysaccharides / Q000008:administration & dosage; D011655:Pulmonary Embolism / Q000188:drug therapy* / Q000517:prevention & control; D053828:Stockings, Compression; D015912:Thrombolytic Therapy; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000517:prevention & control; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin; D006495:Heparin, Low-Molecular-Weight; D011134:Polysaccharides; D014859:Warfarin; D000990:Antithrombin III; D000077425:Fondaparinux