Venous thromboembolism in children.
With improved pediatric survival from serious underlying illnesses, greater use of invasive vascular procedures and devices, and a growing awareness that vascular events occur among the young, venous thromboembolism (VTE) increasingly is recognized as a critical pediatric concern. This review provides background on etiology and epidemiology in this disorder, followed by an in-depth discussion of approaches to the clinical characterization, diagnostic evaluation, and management of pediatric VTE. Prognostic indicators and long-term outcomes are considered, with emphasis on available evidence underlying current knowledge and key questions for further investigation.
Goldenberg
Neil A
NA
Mountain States Regional Hemophilia and Thrombosis Center, P.O. Box 6507, Mail-Stop F-416, Aurora, CO 80045-0507, USA. neil.goldenberg@uchsc.edu
Bernard
Timothy J
TJ
D000925:Anticoagulants / Q000008:administration & dosage; D002648:Child; D003952:Diagnostic Imaging; D006801:Humans; D011379:Prognosis; D013923:Thromboembolism / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D015912:Thrombolytic Therapy / Q000379:methods; D020246:Venous Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy
D000925:Anticoagulants