title: A case of Churg-Strauss syndrome with refractory otitis media.
abstract: OBJECTIVE
  Churg-Strauss syndrome (CSS) is known as autoimmune vasculitis with peripheral eosinophilia after bronchial asthma and rarely has otological findings. We present a case of CSS with refractory otitis media and discuss the relationship between otological symptoms of CSS and eosinophilic otitis media.
  
  
  METHODS
  A 60-year-old woman had suffered from recurrent sinusitis for 8 years, and also otitis media with effusion for 4 months. Eruption with peripheral eosinophilia was found in the lower legs; therefore, she was diagnosed with CSS. She was treated with systemic administration of prednisolone, intratympanic injection of betamethasone, and betamethasone nasal spray; thereafter, eosinophilia, otitis media and sinusitis rapidly improved.
  
  
  CONCLUSIONS
  The features of eosinophilic otitis media are similar to the otological symptoms of CSS. It should be considered whether patients with eosinophilic otitis media have early phase CSS.
authors.affiliation: Department of Otolaryngology, Takarazuka Municipal Hospital, Hyogo, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Saka
authors.forename: Toru
authors.initials: T
authors.lastname: Seo
authors.forename: Koichi
authors.initials: K
authors.lastname: Shimano
authors.forename: Keiko
authors.initials: K
authors.lastname: Kashiba
authors.forename: Tadashi
authors.initials: T
authors.lastname: Mori
authors.forename: Masafumi
authors.initials: M
authors.lastname: Sakagami
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology; D015267:Churg-Strauss Syndrome / Q000175:diagnosis*; D004802:Eosinophilia / Q000209:etiology; D005260:Female; D006312:Hearing Loss, Bilateral / Q000209:etiology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000209:etiology*; D012008:Recurrence; D012852:Sinusitis / Q000209:etiology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007073:Immunoglobulin E