Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.
Löser
Reik
R
Pharmazeutisches Institut, Pharmazeutische Chemie I, Rheinische Friedrich-Wilhelms-Universität, An der Immenburg 4, 53121 Bonn, Germany.
Frizler
Maxim
M
Schilling
Klaus
K
Gütschow
Michael
M
D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D015853:Cysteine Proteinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D009570:Nitriles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D010206:Papain / Q000037:antagonists & inhibitors*
D001372:Aza Compounds; D015853:Cysteine Proteinase Inhibitors; D004151:Dipeptides; D009570:Nitriles; D010206:Papain