title: Risk factors contributing to fascioliasis endemicity in a focus in Dakahlia Governorate 1-human host.
abstract: Zoonotic fascioliasis is a problem not only in Dakahlia Governorate, but also in other Egyptian Governorates. Two hundreds & twenty patients randomly selected with suggesting manifestations were examined for fascioliasis. A total of 23 (10.4%) were positive by Kato thick smears, of which 21 were from Kafr El-Hessah and two from Oweish El-Hager. The proven human fascioliasis was examined for anti-Fasciola antibodies by IHAT & ELISA (Fhes), haemoglobin level, eosinophils percent, serum bilirubin & liver function tests. IHAT gave 82.61% positive results (19/23), and ELISA gave 100% positive results (23/23). The clinical signs ranged between splenomegaly & ascitis in 4.34% for each up to hepatomegaly in 73.91% & mild fever in 78.26% but 2 cases were asymptomatic. Mild eosinophilia and moderate anaemia were recorded with means of 11 +/- 5.8 and 10 +/- 1.3 respectively. Mean serum bilirubin was not elevated (0.91 +/- 0.51 gm/dl). Liver function tests (AST within normal range in all cases; <40 unit/ml but one patient had ALT above normal; >45 unit/ml).
authors.affiliation: Department of Parasitology, Faculty of Medicine, Al-Azhar University for Girls, Cairo, Egypt.
authors.forename: Saedia A Sayed
authors.initials: SA
authors.lastname: El-Ahl
authors.forename: Atef M A
authors.initials: AM
authors.lastname: El Shazly
authors.forename: Amal A M
authors.initials: AA
authors.lastname: El Shafei
authors.forename: Mai A
authors.initials: MA
authors.lastname: Hegazi
authors.forename: Marwa A
authors.initials: MA
authors.lastname: El-Dardiry
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004534:Egypt / Q000453:epidemiology; D005209:Fasciola / Q000276:immunology*; D005211:Fascioliasis / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology / Q000635:transmission; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016036:Seroepidemiologic Studies; D015047:Zoonoses
chemical_list: D000909:Antibodies, Helminth