title: Neuromyelitis optica: brain abnormalities in a Brazilian cohort.
abstract: Neuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck criteria for this disease, with abnormal brain MRI and discuss their clinical and radiological features.
authors.affiliation: Neurology and Neurosurgery Department, Federal University of São Paulo, São Paulo, SP, Brazil. denisbichuetti@globo.com
authors.forename: Denis Bernardi
authors.initials: DB
authors.lastname: Bichuetti
authors.forename: René Leandro Magalhães
authors.initials: RL
authors.lastname: Rivero
authors.forename: Daniel May
authors.initials: DM
authors.lastname: Oliveira
authors.forename: Nilton Amorin de
authors.initials: NA
authors.lastname: Souza
authors.forename: Nitamar
authors.initials: N
authors.lastname: Abdala
authors.forename: Enedina Maria Lobato
authors.initials: EM
authors.lastname: Oliveira
authors.forename: Alberto Alain
authors.initials: AA
authors.lastname: Gabbai
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies