Identifying methamphetamine users at risk for major depressive disorder: findings from the methamphetamine treatment project at three-year follow-up.
Little is known about risk factors for depression in methamphetamine users. Using data from 526 adults in the largest psychosocial clinical trial of methamphetamine users conducted to date, this study examined clinical, demographic, and substance use characteristics that predict the presence of a diagnosis of major depressive disorder (MDD) three years after treatment for methamphetamine dependence. The results indicate that two risk factors predict a diagnosis of MDD: a Beck Depression Inventory total score greater than 20, and one or more prior suicide attempts. These risk factors identify methamphetamine users who may benefit from early interventions for psychiatric symptoms.
Glasner-Edwards
Suzette
S
Integrated Substance Abuse Programs, University of California, Los Angeles, California 90025, USA. sglasner@ucla.edu
Mooney
Larissa J
LJ
Marinelli-Casey
Patricia
P
Hillhouse
Maureen
M
Ang
Alfonso
A
Rawson
Richard
R
D000328:Adult; D000437:Alcoholism / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation; D019969:Amphetamine-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation*; D000697:Central Nervous System Stimulants / Q000633:toxicity*; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000633:toxicity*; D008137:Longitudinal Studies; D008297:Male; D008694:Methamphetamine / Q000633:toxicity*; D008875:Middle Aged; D010555:Personality Inventory; D012307:Risk Factors; D012737:Sex Factors; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D013406:Suicide, Attempted / Q000523:psychology / Q000706:statistics & numerical data
D000697:Central Nervous System Stimulants; D013287:Illicit Drugs; D008694:Methamphetamine