title: Severe dilated cardiomyopathy as a consequence of Ecstasy intake.
abstract: Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure with a prevalence of 1:2500. There are several primary and secondary etiologic factors, including gene mutations, infection agents, particularly viruses, toxins, autoimmune, and systemic disorders, and pheochromocytoma, neuromuscular, metabolic, mitochondrial, and nutritional disorders. However, a precise diagnosis can be reached only in no more than 50% of all cases. Herein, we report a rare case of hepatic damage and severe DCM as a consequence of relatively popular socially used narcotic-Ecstasy (3,4-methylenedioxy-N-methylamphetamine [MDMA]).
authors.affiliation: Department of Cardiology, Medical University of Silesia, Katowice, Poland. Kmizia@op.pl
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Mizia-Stec
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Gasior
authors.forename: Romuald
authors.initials: R
authors.lastname: Wojnicz
authors.forename: Maciej
authors.initials: M
authors.lastname: Haberka
authors.forename: Marcin
authors.initials: M
authors.lastname: Mielczarek
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wierzbicki
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Pstraś
authors.forename: Marek
authors.initials: M
authors.lastname: Hartleb
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000139:chemically induced* / Q000473:pathology; D006680:HLA Antigens / Q000378:metabolism; D006213:Hallucinogens / Q000009:adverse effects*; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006333:Heart Failure / Q000139:chemically induced; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging; D008099:Liver / Q000000981:diagnostic imaging / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects*; D019966:Substance-Related Disorders / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D014463:Ultrasonography
chemical_list: D006680:HLA Antigens; D006213:Hallucinogens; D018817:N-Methyl-3,4-methylenedioxyamphetamine