title: Women's perception of the efficacy of a soy extract with probiotic: the M3 study.
abstract: OBJECTIVE
  To determine women's perception of soy extracts containing a probiotic on climacteric-related symptoms.
  
  
  METHODS
  A prospective multi-center survey.
  
  
  METHODS
  A total of 2044 women aged 40-65 years, who were recruited at random by a group of 198 Spanish gynecologists. The women completed a self-report survey at baseline and after 6 months' use of the soy extract (30 mg genistein and 30 mg daidzein) with probiotic (500 million spores of Lactobacillus sporogenes), calcium (141 mg) and vitamin D (5 microg). The questionnaire included 15 items on menopause and health and four about sexuality from the Cervantes scale. Patients and gynecologists completed an assessment about the clinical state.
  
  
  RESULTS
  After 6 months, the studied soy extract improved climacteric symptoms and sexuality. Both patients and gynecologists were satisfied with the results.
  
  
  CONCLUSIONS
  Peri- and postmenopausal patients usually experience common menopausal symptoms and many believe that soy extract improves their menopause symptoms. Physicians should be aware of patients' positive attitude to such products.
authors.affiliation: Instituto Palacios de Salud y, Medicina de la Mujer, Madrid, Spain. ipalacios@institutopalacios.com
authors.forename: Santiago
authors.initials: S
authors.lastname: Palacios
authors.forename: Ignacio Alvarez
authors.initials: IA
authors.lastname: Rojo
authors.forename: Maria Jesús
authors.initials: MJ
authors.lastname: Cancelo
authors.forename: José Luis
authors.initials: JL
authors.lastname: Neyro
authors.forename: Camil
authors.initials: C
authors.lastname: Castelo-Branco
mesh_terms: D000328:Adult; D000368:Aged; D002979:Climacteric / Q000187:drug effects / Q000523:psychology*; D005260:Female; D006801:Humans; D007778:Lactobacillus; D008875:Middle Aged; D010465:Perception / Q000187:drug effects / Q000502:physiology*; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D019936:Probiotics / Q000008:administration & dosage / Q000494:pharmacology*; D011788:Quality of Life; D030262:Soybean Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D010936:Plant Extracts; D030262:Soybean Proteins