title: Histologic analysis of human peri-implant bone in type 1 osteoporosis.
abstract: Osteoporosis is a disease that influences the quality of bone tissue. At present, osteoporosis represents a contraindication or a risk factor for osseointegration. The aim of this report was to evaluate the bone-to-implant contact of 2 loaded implants retrieved after prosthetic failure in a woman with type 1 osteoporosis. Histologically, only one implant was osseointegrated, and it appeared surrounded by healthy bone tissue. The bone-to-implant contact presented a mean of 51.25%. No foreign body reaction was found at the bone-to-implant contact, although epithelial downgrowth was observed at the interface. Data from this case report demonstrate that the peri-implant bone histology of the dental implant retrieved from an osteoporotic patient presented no alteration. However, the role of osteoporosis in the long-term success of dental implants needs further investigation.
authors.affiliation: Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil. jshibli@ung.br
authors.forename: Jamil Awad
authors.initials: JA
authors.lastname: Shibli
authors.forename: Kelly Christine Dias de Souza
authors.initials: KC
authors.lastname: Aguiar
authors.forename: Leandro
authors.initials: L
authors.lastname: Melo
authors.forename: Daniel Sanchez
authors.initials: DS
authors.lastname: Ferrari
authors.forename: Susana
authors.initials: S
authors.lastname: D'Avila
authors.forename: Giovanna
authors.initials: G
authors.lastname: Iezzi
authors.forename: Adriano
authors.initials: A
authors.lastname: Piattelli
mesh_terms: D000075202:Contraindications; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D019232:Dental Restoration Failure; D003799:Dental Stress Analysis; D020878:Device Removal; D005260:Female; D006801:Humans; D008875:Middle Aged; D016348:Osseointegration; D015663:Osteoporosis, Postmenopausal / Q000503:physiopathology*; D012307:Risk Factors
chemical_list: D015921:Dental Implants