title: Quality assurance of ultrasound imaging systems for target localization and online setup corrections.
abstract: We describe quality assurance paradigms for ultrasound imaging systems for target localization (UISTL). To determine the absolute localization accuracy of a UISTL, an absolute coordinate system can be established in the treatment room and spherical targets at various depths can be localized. To test the ability of such a system to determine the magnitude of internal organ motion, a phantom that mimics the human male pelvic anatomy can be used to simulate different organ motion ranges. To assess the interuser variability of ultrasound (US) guidance, different experienced users can independently determine the daily organ shifts for the same patients for a number of consecutive fractions. The average accuracy for a UISTL for the localization of spherical targets at various depths has been found to be 0.57 +/- 0.47 mm in each spatial dimension for various focal depths. For the phantom organ motion test it was found that the true organ motion could be determined to within 1.0 mm along each axis. The variability between different experienced users who localized the same 5 patients for five consecutive fractions was small in comparison to the indicated shifts. In addition to the quality assurance tests that address the ability of a UISTL to accurately localize a target, a thorough quality assurance program should also incorporate the following two aspects to ensure consistent and accurate localization in daily clinical use: (1) adequate training and performance monitoring of users of the US target localization system, and (2) prescreening of patients who may not be good candidates for US localization.
authors.affiliation: Department of Human Oncology, University of Wisconsin, Clinical Science Center, Madison, WI 53792, USA. tome@humonc.wisc.edu
authors.forename: Wolfgang A
authors.initials: WA
authors.lastname: Tomé
authors.forename: Nigel P
authors.initials: NP
authors.lastname: Orton
mesh_terms: D002138:Calibration; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging / Q000592:standards*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging; D011786:Quality Control; D015203:Reproducibility of Results; D014463:Ultrasonography / Q000295:instrumentation*