title: Changes in DT vaccine frequency and indications for use following introduction of DTaP vaccine.
abstract: Our population-based study among HMO members under seven years of age in 1993-2000 showed that frequency of diphtheria and tetanus toxoid vaccine (DT) use declined significantly following the introduction of acellular pertussis-containing (DTaP) vaccine. We also observed changes in indications for DT following the transition to DTaP among children under two years of age; notably, a decline in the proportion of children receiving DT due to a reported prior vaccine reaction and an increase in the proportion of children receiving DT due to parental request and a history of pertussis.
authors.affiliation: Group Health Center for Health Studies, Seattle, Washington 98101-1448, USA. Benson.p@ghc.org
authors.forename: Patti J
authors.initials: PJ
authors.lastname: Benson
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Jackson
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Rees
authors.forename: John B
authors.initials: JB
authors.lastname: Dunn
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D022422:Diphtheria-Tetanus Vaccine / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology*; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology*; D004363:Drug Utilization / Q000639:trends*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014917:Whooping Cough / Q000517:prevention & control*
chemical_list: D022422:Diphtheria-Tetanus Vaccine; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines