Catalase-negative Staphylococcus aureus strain with point mutations in the katA gene.
Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, including one leading to a substitution of key histidine 58 by a tyrosine.
Piau
C
C
Service de Microbiologie, Université de Caen Basse-Normandie, CHU Côte de Nacre, 14033 Caen cedex, France.
Jehan
J
J
Leclercq
R
R
Daurel
C
C
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000150:complications; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002374:Catalase / Q000235:genetics* / Q000378:metabolism; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis / Q000382:microbiology*; D017354:Point Mutation; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000201:enzymology* / Q000235:genetics
D001426:Bacterial Proteins; D002374:Catalase