[Detection of MMP-11 from menstrual blood using immunohistochemistry].
OBJECTIVE
To prove the feasibility of detecting menstrual blood as well as its cellular localization with rabbit-anti-human matrix metalloproteinase-11 (MMP-11) polyclonal antibody.


METHODS
MMP-11 in menstrual blood, peripheral blood, vaginal liquid, aged menstrual bloodstain, and endometrium sections were assayed with SAP immunohistochemistry.


RESULTS
MMP-11 was found only in menstrual samples within stroma and epithelium cells.


CONCLUSIONS
MMP-11 polyclonal antibody may be applied in the distinction between menstrual blood and venous blood.
Yao
Ya-Nan
YN
Department of Forensic Biology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Lu
Hui-Ling
HL
Chen
Sen
S
Zheng
Jing
J
Zhang
Ya-Qing
YQ
D000328:Adult; D004717:Endometrium / Q000473:pathology; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D007150:Immunohistochemistry; D053507:Matrix Metalloproteinase 11 / Q000032:analysis*; D008597:Menstrual Cycle / Q000097:blood*
D053507:Matrix Metalloproteinase 11