Wilms tumour in Sudan.
BACKGROUND
Wilms tumour is one of the commonest childhood solid tumours which has an excellent outlook in the developed world with 5-year overall survival exceeding 90%. There is little information from Sudan regarding Wilms tumour.


METHODS
Records of patients with Wilms tumour diagnosed and treated at Institute of Nuclear Medicine, Molecular Biology and Oncology (INMO) in the University of Gezira from May 1999 to June 2007 were reviewed.


RESULTS
Thirty-seven children presented at a mean age of 4.1 years (range 2 months-13 years). The male to female ratio was 0.9-1. Abdominal swelling or mass was the commonest symptom. There was 1 child with Stage I (2.7%), 7 with stage II (18.9%), 25 with Stage III (67.6%) and 4 with Stage IV (10.8%). Following diagnosis 27% of children did not receive further treatment (5.4% died prior to treatment, 5.4% were not able to finance treatment and for the rest 16.2% no cause was identified). More than half of the children did not have a nephrectomy and only 4 (11%) completed treatment.


CONCLUSIONS
The poor outlook is related to several factors. Delayed presentation, poor awareness of treatment options, lack of finances, no provision of food, lodging and transport, absence of paediatric trained staff are the obstacles to better outcomes. Empowering parents with information, giving chemotherapy prior to nephrectomy, training staff and establishing links with a tertiary cancer centre in the developed world are some of the options to improve survival.
Abuidris
Dafalla O
DO
Department of Radiation Oncology, Institute of Nuclear Medicine, Molecular Biology and Oncology, University of Gezira, Wad Madani, Sudan. abuidris@yahoo.com
Elimam
Mohammed E
ME
Nugud
Faisal M
FM
Elgaili
Elgaili M
EM
Ahmed
Mohamed E
ME
Arora
Ramandeep S
RS
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D013397:Sudan / Q000453:epidemiology; D009396:Wilms Tumor / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*