title: Hypokalemic rhabdomyolysis in a child with 11-hydroxylase deficiency.
abstract: Myopathy is a well-recognized complication of persistent hypokalemia. Although hypokalemic myopathy may be due to divers diseases or to drug administration, hypokalemic rhabdomyolysis as a complication of under-treated 11-hydroxylase deficiency has not previously been described in the literature. We describe a 10-year-old boy with under-treated 11-hydroxylase deficiency who developed rhabdomyolysis following severe hypokalemia. Patients with under-treated 11-hydroxylase deficiency may present with hypokalemia in association with muscle weakness; if serum potassium is markedly low, rhabdomyolysis may occur. Hypokalemia-induced rhabdomyolysis should be carefully followed.
authors.affiliation: Department of Pediatric Endocrinology, Faculty of Medicine, Selcuk University, Turkey.
authors.forename: Mehmet Emre
authors.initials: ME
authors.lastname: Atabek
authors.forename: Ozgur
authors.initials: O
authors.lastname: Pirgon
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sert
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000150:complications*; D002648:Child; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000175:diagnosis; D008297:Male; D011188:Potassium / Q000097:blood; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology*; D013252:Steroid 11-beta-Hydroxylase / Q000378:metabolism*
chemical_list: D013252:Steroid 11-beta-Hydroxylase; D011188:Potassium