Entamoeba invadens: influence of 60 Hz magnetic fields on growth and differentiation.
Exposure to extremely low-frequency (ELF) electromagnetic fields appears to result in a number of important biological changes. In the present study, we evaluated the effects of 60 Hz sinusoidal magnetic fields (MF) at magnetic flux densities of 1.0, 1.5 and 2.0 mT on growth and differentiation of the protozoan Entamoeba invadens. We demonstrated an inhibitory growth effect when trophozoite cultures were exposed to 1.5 and 2.0 mT. Furthermore, we found that there was not a synergistic effect in cultures co-exposed to MF and Metronidazole, a cytotoxic drug against amoebic cells. In addition, MF exposure inhibited the encystation process of E. invadens.
Rodríguez-De la Fuente
Abraham O
AO
Subdirección de Postgrado, Facultad de Ciencias Biológicas, UANL, Serafín Peña 909 Norte, Monterrey, Mexico. abrrodriguez@fcb.uanl.mx
Heredia-Rojas
J Antonio
JA
Mata-Cárdenas
Benito David
BD
Vargas-Villarreal
Javier
J
Rodríguez-Flores
Laura E
LE
Balderas-Candanosa
Isaías
I
Alcocer-González
Juan M
JM
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields; D004747:Entamoeba / Q000187:drug effects / Q000254:growth & development* / Q000502:physiology / Q000528:radiation effects*; D007928:Lethal Dose 50; D008795:Metronidazole / Q000494:pharmacology; D011897:Random Allocation
D000981:Antiprotozoal Agents; D008795:Metronidazole