Two new flavonoids from Centella asiatica (Linn.).
Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC(50) values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.
Subban
Ravi
R
Veerakumar
A
A
Manimaran
R
R
Hashim
K M
KM
Balachandran
Indira
I
D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D001713:Biphenyl Compounds; D028041:Centella / Q000737:chemistry*; D002726:Chlorogenic Acid / Q000031:analogs & derivatives / Q000302:isolation & purification; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D010851:Picrates; D010936:Plant Extracts; C529863:castillicetin; C529862:castilliferol; C469310:isochlorogenic acid; D002726:Chlorogenic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl