Mo-Au combo catalysis for rapid 1,3-rearrangement of propargyl alcohols into alpha,beta-unsaturated carbonyl compounds.
The combination of Mo and cationic Au catalysts dramatically accelerated the rearrangement of diverse propargyl alcohols, which includes a short reaction time, mild conditions, and high product yields. A practical application to the highly challenging primary propargyl alcohols and the N-alkynyl amides is achieved.
Egi
Masahiro
M
School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Yamaguchi
Yoshiko
Y
Fujiwara
Noboru
N
Akai
Shuji
S
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D008982:Molybdenum / Q000737:chemistry*; D020005:Propanols / Q000737:chemistry*
D000480:Alkynes; D020005:Propanols; D006046:Gold; D008982:Molybdenum; C028255:propargyl alcohol