title: Surface functionalization of porous resorbable scaffolds by covalent grafting.
abstract: Resorbable porous scaffold discs and solid films were prepared from poly[(1,5-dioxepan-2-one)-co-(L-lactide)] and poly[(epsilon-caprolactone)-co-(L-lactide)]. The surfaces of the scaffolds were functionalized to increase their hydrophilicity. A total of 90 samples were prepared to cover all important combinations of experimental and material factors, and all experimental data were fitted by a partial least square model. As a result of grafting, the porous discs and solid films exhibited a tremendous increase in wettability. The functionalized discs were hygroscopic so that water was instantly absorbed and thoroughly wet the substrates.
authors.affiliation: Fiber and Polymer Technology, School of Chemical Science and Engineering, Royal Institute of Technology, SE-100 44 Stockholm, Sweden.
authors.forename: Martina
authors.initials: M
authors.lastname: Källrot
authors.forename: Ulrica
authors.initials: U
authors.lastname: Edlund
authors.forename: Ann-Christine
authors.initials: AC
authors.lastname: Albertsson
mesh_terms: D000042:Absorption; D057927:Hydrophobic and Hydrophilic Interactions; D011091:Polyesters / Q000737:chemistry*; D016062:Porosity; D014867:Water / Q000737:chemistry*; D017155:Wettability
chemical_list: D011091:Polyesters; D014867:Water; C062968:lactide-caprolactone copolymer