Isoflavonoid glycosides and rotenoids from Pongamia pinnata leaves.
Chromatographic separation of a 70% aqueous methanol extract (AME) of Pongamia pinnata (Linn.) Pierre (Leguminosae) leaves has led to the isolation of two new isoflavonoid diglycosides, 4'-O-methyl-genistein 7-O-beta-D-rutinoside (2) and 2',5'-dimethoxy-genistein 7-O-beta-D-apiofuranosyl-(1"'-->6")-O-beta-D-glucopyranoside (6), and a new rotenoid, 12a-hydroxy-alpha-toxicarol (5), together with nine known metabolites, vecinin-2 (1), kaempferol 3-O-beta-D-rutinoside (3), rutin (4), vitexin (7), isoquercitrin (8), kaempferol 3-O-beta-D-glucopyranoside (9), 11,12a-dihydroxy-munduserone (10), kaempferol (11), and quercetin (12). Their structures were elucidated on the basis of chemical and spectroscopic analyses.
Marzouk
Mohamed S A
MS
Chemistry of Natural Products Group, Nobel Project, National Research Centre, El-Behoos St., Dokki, Cairo, Egypt. msmarzouk@yahoo.co.uk
Ibrahim
Magda T
MT
El-Gindi
Omima R
OR
Abou Bakr
Marwa S
MS
D002850:Chromatography, Gel; D019833:Genistein / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D018515:Plant Leaves / Q000737:chemistry*; D052596:Pongamia / Q000737:chemistry*; D012402:Rotenone / Q000737:chemistry / Q000302:isolation & purification*; D013056:Spectrophotometry, Ultraviolet
D006027:Glycosides; D007529:Isoflavones; D012402:Rotenone; D019833:Genistein