title: Transcranial Doppler blood flow assessment in patients with mild heart failure: correlates with neuroimaging and cognitive performance.
abstract: Cardiac output and cerebral perfusion are reduced in patients with advanced stages of heart failure. Our aim was to determine whether cerebral blood flow velocity measured by transcranial Doppler ultrasonography was reduced in outpatients with mild heart failure in comparison to controls and, if so, whether this reduction was related to cognitive performance and abnormalities of the brain diagnosed by magnetic resonance imaging.
authors.affiliation: Department of Neurology, Sint Lucas-Andreas Hospital and the Department of Clinical Neuropsychology, VU University, Amsterdam, the Netherlands. r.vogels@vumc.nl
authors.forename: Raymond L C
authors.initials: RL
authors.lastname: Vogels
authors.forename: Joukje M
authors.initials: JM
authors.lastname: Oosterman
authors.forename: David M
authors.initials: DM
authors.lastname: Laman
authors.forename: Alida A
authors.initials: AA
authors.lastname: Gouw
authors.forename: Jutta M
authors.initials: JM
authors.lastname: Schroeder-Tanka
authors.forename: Philip
authors.initials: P
authors.lastname: Scheltens
authors.forename: Wiesje M
authors.initials: WM
authors.lastname: van der Flier
authors.forename: Henry C
authors.initials: HC
authors.lastname: Weinstein
mesh_terms: D000368:Aged; D001921:Brain / Q000098:blood supply*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003071:Cognition; D003072:Cognition Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011594:Psychometrics; D012039:Regional Blood Flow; D017585:Ultrasonography, Doppler, Transcranial