title: Stroke in a child with neurofibromatosis type 2.
abstract: Neurofibromatosis types 1 (NF1) and 2 (NF2) are genetically distinct conditions caused by mutations in tumour suppressor genes that share a number of phenotypic features. Childhood stroke and vasculopathy have been associated with NF1, but not with NF2. We describe a case of brainstem stroke in a child with NF2.
authors.affiliation: Department of Paediatric Neurology, Sheffield Children's Hospital, Western Bank, Sheffield, UK. drjoanneng@doctors.org.uk
authors.forename: Joanne
authors.initials: J
authors.lastname: Ng
authors.forename: Santosh R
authors.initials: SR
authors.lastname: Mordekar
authors.forename: Daniel J A
authors.initials: DJ
authors.lastname: Connolly
authors.forename: Peter
authors.initials: P
authors.lastname: Baxter
mesh_terms: D000293:Adolescent; D001933:Brain Stem / Q000473:pathology*; D005158:Facial Paralysis / Q000209:etiology / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D016518:Neurofibromatosis 2 / Q000150:complications / Q000235:genetics / Q000473:pathology*; D025581:Neurofibromin 2 / Q000235:genetics; D009759:Nystagmus, Pathologic / Q000209:etiology / Q000473:pathology; D010291:Paresis / Q000209:etiology / Q000473:pathology; D017354:Point Mutation; D020521:Stroke / Q000150:complications / Q000473:pathology*
chemical_list: D025581:Neurofibromin 2