1,2-Addition of trialkylaluminium reagents to N-diphenylphosphinoylketimines in the absence of any additional reagents.
Using reactive trialkylaluminium reagents for the 1,2-addition on acetophenone- and benzophenone-derived ketimines, alpha-trisubstituted amines were obtained in excellent yields up to 99%.
Reingruber
Rüdiger
R
Institut für Organische Chemie, Universität Karlsruhe (TH), Fritz-Haber-Weg 6, D-76131, Karlsruhe, Germany.
Bräse
Stefan
S
D000478:Alkylation; D000535:Aluminum / Q000737:chemistry*; D000588:Amines / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure
D000588:Amines; D007659:Ketones; D000535:Aluminum