title: [Benefits of cardiac resynchronization therapy in patients with atrial fibrillation who have not undergone atrioventricular node ablation].
abstract: The aim of this study was to compare the effects of cardiac resynchronization therapy on left ventricular function and reverse remodeling in patients in sinus rhythm with the effects in patients with atrial fibrillation who have not undergone atrioventricular node ablation. Echocardiographic and clinical parameters were evaluated at baseline and after 6 months of cardiac resynchronization therapy in 55 patients: 15 had atrial fibrillation and 40 were in sinus rhythm. Device programming was similar in the 2 groups, as were the reductions in QRS interval and echocardiographic measures of asynchrony observed after implantation. However, although significant improvements in end-systolic volume and ejection fraction were seen in both groups, reverse remodeling was greater in patients in sinus rhythm (reduction in end-systolic volume 30.9%+/-24.6% vs 12.5%+/-18.6%; P=.024), as was the relative increase in ejection fraction (15.4%+/-12.6% vs 5.0%+/-7.2%; P=.010). Cardiac resynchronization therapy in patients with atrial fibrillation who had not undergone atrioventricular node ablation resulted in significant improvements in ejection fraction and reverse remodeling, but these were less than those observed in patients in sinus rhythm.
authors.affiliation: Servicio de Cardiología, Hospital Virgen de la Victoria, Málaga, España. fcabrerab@secardiologia.es
authors.forename: Fernando
authors.initials: F
authors.lastname: Cabrera-Bueno
authors.forename: José
authors.initials: J
authors.lastname: Peña-Hernández
authors.forename: Julia
authors.initials: J
authors.lastname: Fernández-Pastor
authors.forename: Alberto
authors.initials: A
authors.lastname: Barrera-Cordero
authors.forename: José M
authors.initials: JM
authors.lastname: García-Pinilla
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Gómez-Doblas
authors.forename: Javier
authors.initials: J
authors.lastname: Alzueta-Rodríguez
authors.forename: Eduardo
authors.initials: E
authors.lastname: de Teresa-Galván
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000628:therapy*; D001283:Atrioventricular Node; D002304:Cardiac Pacing, Artificial; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016277:Ventricular Function, Left