title: Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patch.
abstract: A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate LAVV regurgitation. At that reoperation, she had a Dacron patch enlargement of the infundibular septum and repair of her LAVV with a xenograft (bovine) pericardial patch sutured into the superior bridging leaflet. LAVV replacement was required 8 years later because of valve insufficiency. There was a perforation in the patch with fibrosis, thickening due to pannus, and calcification of the pericardial tissue and the leaflet tissue, leading to stiffening of the tissue.
authors.affiliation: Department of Pathology, Toronto General Hospital/University Health Network, Canada.
authors.forename: Adriana
authors.initials: A
authors.lastname: Luk
authors.forename: Eric
authors.initials: E
authors.lastname: Ahn
authors.forename: Gursharan S
authors.initials: GS
authors.lastname: Soor
authors.forename: William G
authors.initials: WG
authors.lastname: Williams
authors.forename: Melitta
authors.initials: M
authors.lastname: Mezody
authors.forename: Jagdish
authors.initials: J
authors.lastname: Butany
mesh_terms: D000328:Adult; D000818:Animals; D002114:Calcinosis; D002417:Cattle; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006345:Heart Septal Defects, Ventricular / Q000601:surgery*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006351:Heart Valves / Q000473:pathology / Q000601:surgery*; D006801:Humans; D010496:Pericardium / Q000601:surgery* / Q000637:transplantation; D011093:Polyethylene Terephthalates; D012086:Reoperation; D014183:Transplantation, Heterologous; D016896:Treatment Outcome
chemical_list: D011093:Polyethylene Terephthalates