title: Influence of antiretroviral treatment on quality of life in seropositive inmates.
abstract: The aim of the study is to evaluate the influence of antiretroviral treatment on health-related quality of life (HRQOL) of three groups of HIV-positive inmates: those who are taking antiretroviral treatment, those who are not on treatment as it has not yet been indicated, and those who refuse to take treatment even though it has been recommended. A cross-sectional study was conducted on 585 HIV+ inmates in three prisons. The response variable was HRQOL. Independent variables were: sociodemographic variables, psychosocial and drug-related variables. Two multivariate linear regression models were constructed in order to determine the HRQOL, physical health score (PHS) and mental health score (MHS), for each of the three groups identified, using patients who refused treatment as the reference category. Patients who refused therapy had a lower MHS compared with patients in whom treatment was not indicated (P = 0.038). With regard to PHS, patients refusing therapy had a lower score than patients who were not indicated therapy (P = 0.005), and than patients receiving therapy (P = 0.010).
authors.affiliation: Preventive Service, Hospital Virgen de las Nieves, Granada, Spain.
authors.forename: L Sordo
authors.initials: LS
authors.lastname: del Castillo
authors.forename: I
authors.initials: I
authors.lastname: Ruiz-Pérez
authors.forename: A Olry
authors.initials: AO
authors.lastname: de Labry-Lima
authors.forename: J M
authors.initials: JM
authors.lastname: Soto-Blanco
authors.forename: E
authors.initials: E
authors.lastname: Girela-López
authors.forename: J M
authors.initials: JM
authors.lastname: Castro-Recio
authors.forename: J J
authors.initials: JJ
authors.lastname: Antón-Basanta
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D005260:Female; D006679:HIV Seropositivity / Q000188:drug therapy* / Q000523:psychology*; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D011329:Prisoners; D011330:Prisons; D011788:Quality of Life; D013030:Spain; D011795:Surveys and Questionnaires
chemical_list: D019380:Anti-HIV Agents