title: Reconstruction of standard 12-lead electrocardiograms from 12-lead electrocardiograms recorded with the Mason-Likar electrode configuration.
abstract: Electrocardiograms (ECGs) made with Mason-Likar electrode configuration (ML-ECGs) show well-known differences from standard 12-lead ECGs (Std-ECGs). We recorded, simultaneously, Std-ECGs and ML-ECGs in 180 subjects. Using these ECGs, 8 x 8 individual and general conversion matrices were created by linear regression, and standard ECGs were reconstructed from ML-ECGs using these matrices. The performance of the matrices was assessed by the root mean square differences between the original Std-ECGs and the reconstructed standard ECGs, by the differences in major ECG parameters, and by comparison of computer-generated diagnostic statements. As a result, we conclude that, based on the root mean square differences, reconstructions with 8 x 8 individual matrices perform significantly better than reconstructions with the group matrix and perform equally well with respect to the calculation of major electrocardiographic parameters, which gives an improved reliability of the QRS frontal axis and the maximal QRS and T amplitudes. Both types of matrices were able to reverse the underdiagnosis of inferior myocardial infarctions and the erroneous statements about the QRS frontal axis that arose in the ECGs that were made by using the Mason-Likar electrode positions.
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Sum-Che
authors.initials: SC
authors.lastname: Man
authors.forename: Arie C
authors.initials: AC
authors.lastname: Maan
authors.forename: Eunhyo
authors.initials: E
authors.lastname: Kim
authors.forename: Harmen H M
authors.initials: HH
authors.lastname: Draisma
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
authors.forename: Ernst E
authors.initials: EE
authors.lastname: van der Wall
authors.forename: Cees A
authors.initials: CA
authors.lastname: Swenne
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D018780:Body Surface Potential Mapping / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D004566:Electrodes / Q000592:standards; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity