title: [The consequences of closed traumatic brain injury and piracetam efficacy in their treatment in adolescents].
abstract: The efficacy of piracetam in the treatment of the consequences of moderate and severe closed traumatic brain injury was assessed in 42 patients, aged 12-18 years, who suffered traumatic disorders 1,5-5 years before this study. Adolescents from the main group (20 patients) received piracetam in dosage of 40-50 mg/kg (or 1600-2400 mg daily) during one month. 22 patients of the second group were examined as controls. The positive therapeutic effects of piracetam on cognitive (memory, attention, executive functions) and motor (coordination) functions as well as the speed of cognitive and motor performance were demonstrated in this study.
authors.forename: N N
authors.initials: NN
authors.lastname: Zavadenko
authors.forename: L S
authors.initials: LS
authors.lastname: Guzilova
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001288:Attention / Q000187:drug effects; D001930:Brain Injuries / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D018697:Nootropic Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010889:Piracetam / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011597:Psychomotor Performance / Q000187:drug effects; D013997:Time Factors
chemical_list: D018696:Neuroprotective Agents; D018697:Nootropic Agents; D010889:Piracetam