title: Lymphoid interstitial pneumonia associated with common variable immunoglobulin deficiency.
abstract: The patient was a 30-year-old woman with a disease of common variable immunodeficiency. She was admitted to our hospital because of abnormal findings on her chest radiographs in an annual health screening. Chest computed tomography showed multiple reticulonodular infiltrates in both lower lung fields. The surgical lung biopsy specimen demonstrated involvement of mature small lymphocytes with a mixture of other mononuclear cells in the lung parenchyma and bronchiolar walls. The patient was diagnosed to have lymphoid interstitial pneumonia. The patient was treated with prednisolone and intravenous supplement of immunoglobulin, resulting in radiographically and clinically stable disease.
authors.affiliation: The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto. mtsunoda@hsp.md.shinshu-u.ac.jp
authors.forename: Mikako
authors.initials: M
authors.lastname: Matsubara
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Koizumi
authors.forename: Toshihide
authors.initials: T
authors.lastname: Wakamatsu
authors.forename: Keisaku
authors.initials: K
authors.lastname: Fujimoto
authors.forename: Keishi
authors.initials: K
authors.lastname: Kubo
authors.forename: Takayuki
authors.initials: T
authors.lastname: Honda
mesh_terms: D000328:Adult; D001706:Biopsy; D017074:Common Variable Immunodeficiency / Q000150:complications*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D008214:Lymphocytes / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D011859:Radiography
chemical_list: D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D011239:Prednisolone