title: The role of cyclodextrins in chiral capillary electrophoresis.
abstract: The members of the enantiomeric pairs frequently show rather different biological effects, so their chiral selective synthesis, pharmacological studies and analysis are necessary. CE has unique advantages in chiral analysis. The most frequently used chiral selectors are CDs in this field. This paper gives a short view on the advantages on CE in direct chiral separations, emphasizing the role of CDs. The reason for the broad selectivity spectra of CDs is discussed in detail. The physical background of chiral selective separations is briefly shown in CE. Their interaction mechanisms are shortly defined. The general trend of their use is statistically evaluated. Most frequently used CDs and CD derivatives are characterized. Advantages of ionizable CDs and single-isomer derivatives are shown. The general trend of their use is established.
authors.affiliation: Department of Environmental Engineering, Budapest Tech. Polytechnical Institution, Budapest, Hungary. juvancz.zoltan@rkk.bmf.hu
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Juvancz
authors.forename: Rita Bodáné
authors.initials: RB
authors.lastname: Kendrovics
authors.forename: Róbert
authors.initials: R
authors.lastname: Iványi
authors.forename: Lajos
authors.initials: L
authors.lastname: Szente
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D019075:Electrophoresis, Capillary / Q000379:methods*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
chemical_list: D003505:Cyclodextrins