title: [Case of serious lidocaine intoxication].
abstract: Lidocaine is frequently used as a local anesthetic and has very low incidence of serious complications. I report on a case of lidocaine intoxication in a 66-year-old man who presented with seizure and cardiac periarrest following the brachial plexus block with 450 mg of lidocaine. Twelve minutes after the lidocaine administration, he became unconscious and 29 minutes after, developed seizure. Bradycardia and subsequent cardiovascular depression were found 74 minutes after the lidocaine block. The patient was successfully treated with diazepam, atropine sulphate and transcutaneous pacing for each symptom, respectively.
authors.affiliation: Department of Anesthesiology, Tannan Regional Hospital, Sabae 916-8515.
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Takinami
mesh_terms: D000779:Anesthetics, Local / Q000506:poisoning*; D001285:Atropine / Q000627:therapeutic use; D001917:Brachial Plexus; D002304:Cardiac Pacing, Artificial; D003975:Diazepam / Q000627:therapeutic use; D006323:Heart Arrest / Q000209:etiology / Q000628:therapy; D006801:Humans; D008012:Lidocaine / Q000506:poisoning*; D008297:Male; D009407:Nerve Block / Q000009:adverse effects*; D012640:Seizures / Q000209:etiology / Q000628:therapy; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D001285:Atropine; D008012:Lidocaine; D003975:Diazepam