Chemistry of CpG DNA.
The vertebrate immune system can recognize specific pathogen-associated molecular patterns in invading microorganisms, including the unmethylated CpG dinucleotide. This unit discusses the receptors that recognize CpG motifs and important aspects of the sequence context of CpG motifs to the end of understanding and designing CpG DNA for therapeutic purposes.
Kandimalla
Ekambar R
ER
Hybridon, Inc., Cambridge, Massachusetts, USA.
Agrawal
Sudhir
S
D001483:Base Sequence; D001665:Binding Sites; D018899:CpG Islands / Q000235:genetics* / Q000276:immunology; D004269:DNA, Bacterial / Q000737:chemistry* / Q000276:immunology; D007109:Immunity
D004269:DNA, Bacterial