title: Herpetiform genital lesions in a heifer with mucosal disease.
abstract: A 14-month-old heifer with a 17-day history of unresponsive bloody diarrhea was necropsied. There were focal, pink-red erosions of the nares and hard palate; ulcers and fissures of the tongue; and multiple ulcerative lesions of the alimentary canal. Interdigital skin of both rear limbs was ulcerated and bleeding; and the margins of the vulva contained punctiform red ulcers. The gross lesions were consistent with mucosal disease. Histopathology and laboratory testing ruled out rinderpest, foot-and-mouth disease, and vesicular stomatitis, and identified bovine virus diarrhea virus to be the cause of this disease. Lesions of the vulva similar to those seen in some stages of infectious pustular vulvovaginitis were negative for bovine herpesvirus-1 and tested positive for bovine viral diarrhea virus antigen by immunohistochemistry.
authors.affiliation: Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Fabis
authors.forename: L
authors.initials: L
authors.lastname: Szkudlarek
authors.forename: G R
authors.initials: GR
authors.lastname: Risatti
authors.forename: R
authors.initials: R
authors.lastname: Sura
authors.forename: A E
authors.initials: AE
authors.lastname: Garmendia
authors.forename: H J
authors.initials: HJ
authors.lastname: Van Kruiningen
mesh_terms: D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000473:pathology* / Q000821:virology; D002417:Cattle; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D001908:Diarrhea Viruses, Bovine Viral / Q000235:genetics / Q000254:growth & development*; D017809:Fatal Outcome; D005260:Female; D005831:Genital Diseases, Female / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D016133:Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D004279:DNA, Viral