title: Treatment of traumatic optic neuropathy: our experience of endoscopic optic nerve decompression.
abstract: OBJECTIVE
  Traumatic optic neuropathy can be treated by various methods including steroids and surgical decompression. Endoscopic optic nerve decompression has been suggested to be effective in treating this condition. The aim of this study was to assess the outcome of treating traumatic optic neuropathy with steroids and endoscopic surgical decompression.
  
  
  METHODS
  Two hundred and thirty-seven patients with traumatic optic neuropathy were treated with steroids; 176 also consented to endoscopic optic nerve decompression.
  
  
  RESULTS
  The total vision improvement rate was 55 per cent in the 176 patients treated with both steroids and endoscopic optic nerve decompression, compared with 51 per cent in the 61 patients treated with steroids alone; this difference was not statistically significant (p > 0.05). Treatment with steroids plus endoscopic optic nerve decompression resulted in a significantly greater vision improvement in patients with gradual vision loss, compared with those with immediate blindness (68 vs 42 per cent, respectively). Early surgery (within one week) was an important prognostic factor for vision recovery, compared with more delayed surgical treatment (associated vision improvement rates were 60 and 31 per cent, respectively).
  
  
  CONCLUSIONS
  Endoscopic optic nerve decompression is a minimally invasive, safe and efficient treatment for traumatic optic neuropathy. Used in combination with steroids, it provides effective rescue for some patients suffering visual loss. It should be undertaken as soon as possible.
authors.affiliation: Department of Otolaryngology, The First Affiliated Hospital, Nanjing Medical University, China.
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: B
authors.initials: B
authors.lastname: Zhou
authors.forename: J
authors.initials: J
authors.lastname: Shi
authors.forename: L
authors.initials: L
authors.lastname: Cheng
authors.forename: W
authors.initials: W
authors.lastname: Wen
authors.forename: G
authors.initials: G
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D019299:Decompression, Surgical / Q000379:methods*; D003907:Dexamethasone / Q000627:therapeutic use*; D004724:Endoscopy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020221:Optic Nerve Injuries / Q000188:drug therapy* / Q000601:surgery*; D009915:Orbit / Q000601:surgery; D018570:Risk Assessment; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone