title: Identifying the "source" of recognition memory deficits in patients with Huntington's disease or Alzheimer's disease: evidence from the CVLT-II.
abstract: The present study compared the performance of individuals with Huntington's disease (HD) and Alzheimer's disease (AD) on three types of California Verbal Learning Test-Second Edition (CVLT-II) recognition discriminability indices (RDI): Source, Novel, and Total. The HD and AD groups did not differ significantly on Source RDI (all 16 targets versus the 16 previously presented, List B, distractors). However, HD patients performed significantly better than AD patients on Total RDI (all 16 targets versus all 32 distractors) and Novel RDI (all 16 targets versus 16 new distractors). Implications of these findings on the differentiation of the memory disorders associated with HD and AD are discussed.
authors.affiliation: Psychology Service (116B)-Delis Lab, Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. efine@ucsd.edu
authors.forename: Eric M
authors.initials: EM
authors.lastname: Fine
authors.forename: Dean C
authors.initials: DC
authors.lastname: Delis
authors.forename: Spencer R
authors.initials: SR
authors.lastname: Wetter
authors.forename: Mark W
authors.initials: MW
authors.lastname: Jacobson
authors.forename: Joanne M
authors.initials: JM
authors.lastname: Hamilton
authors.forename: Guerry
authors.initials: G
authors.lastname: Peavy
authors.forename: Jody
authors.initials: J
authors.lastname: Goldstein
authors.forename: Carrie
authors.initials: C
authors.lastname: McDonald
authors.forename: Jody
authors.initials: J
authors.lastname: Corey-Bloom
authors.forename: Mark W
authors.initials: MW
authors.lastname: Bondi
authors.forename: David P
authors.initials: DP
authors.lastname: Salmon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications*; D004192:Discrimination, Psychological / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006816:Huntington Disease / Q000150:complications*; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology*; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D021641:Recognition, Psychology / Q000502:physiology*