Antimycobacterial activity of flavonoids from Lantana camara Linn.
Linaroside (1) and lantanoside (2), two flavonoids isolated from Lantana camara and their common acetyl derivative (3) were examined for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv. These compounds exhibited 30, 37 and 98% inhibition, respectively at 6.25 microg mL(-1) concentration. Among these flavonoids acetylated compound was found to be the most active.
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H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. sabira@khi.comsats.net.pk
Wahab
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Siddiqui
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D000995:Antitubercular Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology*; D032410:Lantana / Q000737:chemistry*; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D035261:Plant Components, Aerial / Q000737:chemistry
D000995:Antitubercular Agents; D005419:Flavonoids