title: Lack of association between Helicobacter pylori and laryngeal carcinoma.
abstract: OBJECTIVE
  To survey the role of Helicobacter pylori at the tissue level as a cause of squamous cell carcinoma of the larynx.
  
  
  METHODS
  A case-control study.
  
  
  METHODS
  In an Otolaryngology Ward at an academic university.
  
  
  METHODS
  Patients with laryngeal cancer as cases and patients with benign laryngeal lesion as controls.
  
  
  METHODS
  In all subjects, specimens of laryngeal tissue were examined by rapid urease test while histopathologic examination was achieved to detect H. Pylori.
  
  
  RESULTS
  Totally, 44 patients (42 men and 2 women) with squamous cell carcinoma of larynx and 30 patients (24 men and 6 women) with benign laryngeal lesions (polyp, nodule, granuloma) were studied, none of which were infected with the bacterium.
  
  
  CONCLUSIONS
  Our results did not show H. Pylori infection among patients with laryngeal cancer (SCC) or benign laryngeal lesions. .
authors.affiliation: Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Iran.
authors.forename: Naderpour
authors.initials: N
authors.lastname: Masoud
authors.forename: Khoshbaten
authors.initials: K
authors.lastname: Manouchehr
authors.forename: Doostmohammadian
authors.initials: D
authors.lastname: Najmeh
authors.forename: Halimi
authors.initials: H
authors.lastname: Monireh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000382:microbiology* / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D016481:Helicobacter Infections / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014510:Urease / Q000378:metabolism
chemical_list: D014510:Urease