[Choroid plexus tumours: cytogenetic analysis of a single case and literature review].
Choroid plexus tumours are intraventricular papillary lesions that are observed in typical papillomas, atypical papillomas and carcinomas. They usually occur in childhood, and can result in hydrocephalus and increased intracranial pressure. The present paper describes a case of choroid plexus papilloma in an adult woman; cytogenetic analysis of the lesion is also presented, which demonstrated the presence of tumour mosaicism. Compared to the chromosomal aberrations observed in previous cases, those in the present tumour do not show significant differences between papillomas harboured in adults and paediatric patients. Moreover, there was no apparent correlation between genetic alternations in typical and atypical papillomas and prognosis or recurrence.
Farnedi
A
A
Dipartimento di Scienze Oncologiche, Sezione di Anatomia Patologica M. Malpighi, Universith di Bologna, Ospedale Bellaria, Bologna.
Marucci
G
G
Tosi
A L
AL
Magrini
E
E
Pession
A
A
D000328:Adult; D000782:Aneuploidy; D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor; D016545:Choroid Plexus Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D019394:Ki-67 Antigen / Q000032:analysis; D010212:Papilloma / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011379:Prognosis
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen