title: Faggot formation in mature neutrophils and metamyelocytes in acute myeloid leukemia without maturation.
abstract: The authors report a rare case of acute myeloid leukemia (AML) M1 with faggot formation in mature neutrophils and metamyelocytes. Although Auer rods in mature neutrophils are occasionally experienced, they are usually found in AML M2, M3, or M4 cases, but not in M1 cases. In addition, faggot formation in mature neutrophils, as seen in this case, is considered to be particularly unusual because most previously reported cases tended to show simple Auer rods except for AML M3 cases. This case also showed trisomy 4 in its karyotype, although its relationship with faggot formation remains unclear.
authors.affiliation: Department of Laboratory Medicine, Kyorin University, Tokyo, Japan. onishi@kyorin-u.ac.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ohnishi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshino
authors.forename: Rika
authors.initials: R
authors.lastname: Yoneyama
authors.forename: Masami
authors.initials: M
authors.lastname: Ishii
authors.forename: Takashi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Fumio
authors.initials: F
authors.lastname: Bessho
mesh_terms: D000293:Adolescent; D002894:Chromosomes, Human, Pair 4 / Q000235:genetics; D042381:Granulocyte Precursor Cells / Q000473:pathology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000473:pathology*; D008297:Male; D009504:Neutrophils / Q000473:pathology*; D014314:Trisomy / Q000235:genetics / Q000473:pathology*