title: Swallowtail bacteriochlorins. Lipophilic absorbers for the near-infrared.
abstract: Bacteriochlorins absorb strongly in the near-infrared spectral region and hence are ideally suited for diverse photomedical applications, yet naturally occurring bacteriochlorins have limited stability and synthetic malleability. A de novo route has been exploited to prepare synthetic bacteriochlorins that bear a geminal dimethyl group in each pyrroline ring for stability and a symmetrically branched 1,5-dimethoxypentyl group attached to each pyrrole ring for solubility in lipophilic media.
authors.affiliation: Department of Chemistry, North Carolina State University; Raleigh, North Carolina 27695-8204, USA.
authors.forename: K Eszter
authors.initials: KE
authors.lastname: Borbas
authors.forename: Christian
authors.initials: C
authors.lastname: Ruzié
authors.forename: Jonathan S
authors.initials: JS
authors.lastname: Lindsey
mesh_terms: D004355:Drug Stability; D015394:Molecular Structure; D011166:Porphyrins / Q000138:chemical synthesis* / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013237:Stereoisomerism
chemical_list: D011166:Porphyrins; C452433:bacteriochlorin