title: Portal vein thrombosis after laparoscopic splenectomy for systemic mastocytosis: a case report and review of the literature.
abstract: BACKGROUND
  Laparoscopic splenectomy has become the surgical procedure of choice for various diseases of the spleen. Portal vein thrombosis (PVT) after splenectomy occurs in 0.5% to 22% of patients. Symptoms are nonspecific and include fever, abdominal pain, and epigastric distress. Risk factors for PVT after splenectomy include underlying hematologic disorders, massive splenectomy, and other hypercoagulable states.
  
  
  METHODS
  We describe a case of PVT in a woman who underwent laparoscopic splenectomy for symptomatic splenomegaly secondary to systemic mastocytosis. The patient was discharged from the hospital without anticoagulation and experienced nonspecific symptoms beginning 10 days postoperatively. Diagnosis of PVT was made by contrast-enhanced abdominal computed tomography. The patient had no underlying risk factors. Anticoagulation treatment facilitated recanalization of the portal vein and this was verified by Doppler ultrasound at follow-up.
  
  
  CONCLUSIONS
  PVT after laparoscopic splenectomy is not uncommon. Signs and symptoms are vague and require a high index of suspicion for timely diagnosis. Anticoagulation is the treatment of choice and allows recanalization of the portal system in the majority of cases.
authors.affiliation: The Western Pennsylvania Hospital, Pittsburgh, PA, USA.
authors.forename: Majed
authors.initials: M
authors.lastname: Maalouf
authors.forename: Pavlos
authors.initials: P
authors.lastname: Papasavas
authors.forename: David
authors.initials: D
authors.lastname: Goitein
authors.forename: Philip F
authors.initials: PF
authors.lastname: Caushaj
authors.forename: Daniel
authors.initials: D
authors.lastname: Gagne
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D005260:Female; D006801:Humans; D010535:Laparoscopy; D034721:Mastocytosis, Systemic / Q000601:surgery*; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging; D013156:Splenectomy / Q000009:adverse effects* / Q000379:methods; D013163:Splenomegaly; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D000925:Anticoagulants