title: [New techniques of structural and functional MRI].
abstract: Magnetic resonance imaging is an imaging technique allowing morphological and functional study of the brain. Algorithmic and technical advances offer new insights in such brain studies using new approaches to search epileptogenic lesion. Voxel based analysis appears as the dominant methodology to study grey and white matter using the following contrast: T1, T2, T2 relaxometry, magnetization transfert and diffusion weighted imaging. Ongoing development focuses on sulcal morphometry and gyrification index, to improve our understanding of developmental epilepsy. Magnetic resonance spectroscopy appears as a promising tool following availability of high field strength clinical MRI and evidence about its utility in the field of epileptology. Functional MRI benefits from such high field strength and new pulse sequence using diffusion gradients to probe neuronal firing.
authors.affiliation: Service dimagerie morphologique et fonctionnelle, université Paris-Descartes, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France. s.rodrigo@ch-sainte-anne.fr
authors.forename: S
authors.initials: S
authors.lastname: Rodrigo
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
authors.forename: P
authors.initials: P
authors.lastname: Jissendi
authors.forename: G
authors.initials: G
authors.lastname: Soto-Ares
authors.forename: J-P
authors.initials: JP
authors.lastname: Pruvo
authors.forename: J-F
authors.initials: JF
authors.lastname: Meder
mesh_terms: D001921:Brain / Q000473:pathology / Q000503:physiopathology; D001923:Brain Chemistry / Q000502:physiology; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000639:trends; D009474:Neurons / Q000502:physiology