title: Emergence of a new clone carrying Panton-Valentine leukocidin genes and staphylococcal cassette chromosome mec type V among methicillin-resistant Staphylococcus aureus in Greece.
abstract: Clonal analysis and PCR screening for the presence of Panton-Valentine leukocidin (PVL) genes was performed among 694 methicillin-resistant Staphylococcus aureus (MRSA) cases collected during a 2-y period in Greece. The detection rate of PVL-positive MRSA is high, both in the community and in hospital. Clonal analysis revealed the predominance among the PVL-positive strains of the clonal complex CC80 (ST80-IV) and the emergence of ST377 clone carrying agr1 allele and SCCmec type V.
authors.affiliation: Department of Microbiology, School of Medicine, University of Patras, Patras, Greece.
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Chini
authors.forename: Efthimia
authors.initials: E
authors.lastname: Petinaki
authors.forename: Héléne
authors.initials: H
authors.lastname: Meugnier
authors.forename: Antigoni
authors.initials: A
authors.lastname: Foka
authors.forename: Michele
authors.initials: M
authors.lastname: Bes
authors.forename: Jerome
authors.initials: J
authors.lastname: Etienne
authors.forename: George
authors.initials: G
authors.lastname: Dimitracopoulos
authors.forename: Iris
authors.initials: I
authors.lastname: Spiliopoulou
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics*; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005098:Exotoxins / Q000235:genetics*; D006115:Greece / Q000453:epidemiology; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D016106:Methicillin Resistance / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction / Q000379:methods; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification* / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D037521:Virulence Factors / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors