title: [The changes of expression and Fc-gamma-receptor's polypeptide composition of fetal small intestine enterocytes in Bos primigenius taurus L].
abstract: The expression and polypeptide composition of Fc-gamma-receptors of enterocytes from Bos primigenius taurus L. intestine at 3-, 5-, 7-, 9- month of fetal development was investigated. The results of immunobloting show similar composition of Fc-gamma-receptors extracted from apical and basolateral membranes. The proteins that bind IgG after PAAG electrophoresis and transferring on nitrocellulose were observed as 120, 87, 72 and 43 kDa polypeptide line. The changes of each polypeptide contents were related to the changes of total content of Fc-gamma-receptor proteins. The rise in concentration of Fc-gamma-receptors on apical membrane was observed from 3-rd to 7-th month of fetal development. Maximal concentration of these proteins was detected on enterocytes at 7-th month of fetal development. Fc-gamma-receptors content on basolateral side was higher than on apical side. The presence of Fc-gamma-receptors on enterocyte's membrane indicates on active recycling of these receptors on plasma membrane and reflects early development of immune system in Bos primigenius taurus L. fetus.
authors.forename: D M
authors.initials: DM
authors.lastname: Masiuk
authors.forename: V S
authors.initials: VS
authors.lastname: Nedzvets'kyĭ
authors.forename: M I
authors.initials: MI
authors.lastname: Tsvilikhovs'kyĭ
authors.forename: P O
authors.initials: PO
authors.lastname: Nerush
mesh_terms: D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D004591:Electrophoresis, Polyacrylamide Gel; D020895:Enterocytes / Q000276:immunology / Q000378:metabolism*; D047109:Fetal Development / Q000276:immunology; D005865:Gestational Age; D007074:Immunoglobulin G / Q000276:immunology / Q000378:metabolism; D007583:Jejunum / Q000166:cytology / Q000196:embryology / Q000276:immunology / Q000378:metabolism; D010455:Peptides / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation; D017452:Receptors, IgG / Q000096:biosynthesis* / Q000737:chemistry
chemical_list: D007074:Immunoglobulin G; D010455:Peptides; D017452:Receptors, IgG