title: Postoperative study of vital capacity and ventilation measurements following elective craniotomy.
abstract: OBJECTIVE
  Changes in pulmonary function commonly occur after general surgery. The aims were to evaluate vital capacity, tidal volume and respiratory frequency among patients undergoing elective craniotomy and to determine possible correlations of these parameters with surgery duration and etiology for neurosurgery.
  
  
  METHODS
  Prospective, open study at a tertiary university hospital.
  
  
  METHODS
  Twenty-six patients underwent elective craniotomy for aneurysm clipping (11) or tumor resection (15). Vital capacity (VC), tidal volume (TV), minute volume (VE) and respiratory rate were determined before the operation and on the first to fourth postoperative days.
  
  
  RESULTS
  There were significant decreases of 25% in VC, 22% in TV and 12% in VE (p < 0.05) and no significant increase in respiratory frequency (5%) on the first postoperative day. VE returned to baseline on the second postoperative day and TV on the third postoperative day, while VC was 8% lower on the fourth postoperative day, compared with before the operation (p < 0.05). VC reduction was significantly greater in patients undergoing aneurysm clipping (43%) than in patients undergoing tumor resection (14%) when surgery duration was more than four hours (p < 0.05), with no significant change when surgery duration was less than four hours.
  
  
  CONCLUSIONS
  Reductions in VC, TV and VE were observed during the postoperative period in patients undergoing aneurysm clipping or tumor resection. The reductions in VC and TV were greater in patients undergoing craniotomy due to aneurysm and with longer surgery duration.
authors.affiliation: Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, Brazil.
authors.forename: Luciana Carrupt Machado
authors.initials: LC
authors.lastname: Sogame
authors.forename: Sonia Maria
authors.initials: SM
authors.lastname: Faresin
authors.forename: Milena Carlos
authors.initials: MC
authors.lastname: Vidotto
authors.forename: José Roberto
authors.initials: JR
authors.lastname: Jardim
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery; D003399:Craniotomy / Q000009:adverse effects* / Q000592:standards; D005260:Female; D006785:Hospitals, University; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control; D011184:Postoperative Period; D011300:Preoperative Care; D011446:Prospective Studies; D012123:Pulmonary Ventilation; D013990:Tidal Volume; D013997:Time Factors; D014797:Vital Capacity