title: Portal venous thrombosis after umbilical vein catheterization.
abstract: OBJECTIVE
  Portal vein thrombosis has been associated with umbilical venous catheterization. This prospective study was done to determine the incidence of neonatal portal venous thrombosis associated with catheterization of the umbilical vein .
  
  
  METHODS
  Neonates who had undergone umbilical vein catheterization for exchange transfusion between March 2003 and March 2004 in Children's Hospital of Tabriz, Iran, were included. Doppler ultrasonography was performed within 1-2 weeks after the removal of the catheter. In the cases with portal venous thrombosis, subsequent serial ultrasonography was performed at intervals of every 1-2 months until clot resolution. Risk factors, if any were identified and correlated with catheter-related thrombi.
  
  
  RESULTS
  Ultrasonography detected clinically silent portal venous thrombosis in 17 (34%) of 50 neonates. Follow-up ultrasonography was available in 13 of 17 babies, and revealed complete or partial resolution in all the cases. Sepsis was identified as a significant risk factor (p < 0.001).
  
  
  CONCLUSIONS
  Umbilical venous catheter-associated thrombosis is common, and spontaneous resolution occurs in most cases.
authors.affiliation: Department of Pediatrics, Tabriz University of Medical Sciences, Tabriz, Iran. hossainpours@yahoo.com
authors.forename: Seddigheh Hosseinpour
authors.initials: SH
authors.lastname: Sakha
authors.forename: Mandana
authors.initials: M
authors.lastname: Rafeey
authors.forename: Mohammad Khazem
authors.initials: MK
authors.lastname: Tarzamani
mesh_terms: D002406:Catheterization, Peripheral / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D011169:Portal Vein; D011446:Prospective Studies; D012307:Risk Factors; D018608:Ultrasonography, Doppler; D014471:Umbilical Veins; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*