How to predict the risk of Parkinson disease in relatives of parkin mutation carriers: a complex puzzle of age, penetrance, and number of mutated alleles.
Klein
Christine
C
Ziegler
Andreas
A
D000483:Alleles; D015331:Cohort Studies; D004252:DNA Mutational Analysis; D006580:Genetic Carrier Screening; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005820:Genetic Testing; D015994:Incidence; D020734:Parkinsonian Disorders / Q000453:epidemiology / Q000235:genetics*; D019683:Penetrance; D018570:Risk Assessment / Q000706:statistics & numerical data; D044767:Ubiquitin-Protein Ligases / Q000235:genetics*
D044767:Ubiquitin-Protein Ligases; C111567:parkin protein