Seasonal cholera from multiple small outbreaks, rural Bangladesh.
Clinical and environmental Vibrio cholerae organisms collected from February 2004 through April 2005 were systematically isolated from 2 rural Bangladeshi locales. Their genetic relatedness was evaluated at 5 loci that contained a variable number of tandem repeats (VNTR). The observed minimal overlap in VNTR patterns between the 2 communities was consistent with sequential, small outbreaks from local sources.
Stine
O Colin
OC
University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. guy.boivin@crchul.ulaval.ca
Alam
Munirul
M
Tang
Li
L
Nair
G Balakrish
GB
Siddique
A Kasem
AK
Faruque
Shah M
SM
Huq
Anwar
A
Colwell
Rita
R
Sack
R Bradley
RB
Morris
J Glenn
JG
D000818:Animals; D001459:Bangladesh / Q000453:epidemiology; D001483:Base Sequence; D002771:Cholera / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D005618:Fresh Water / Q000382:microbiology; D019015:Geologic Sediments / Q000382:microbiology; D006801:Humans; D018598:Minisatellite Repeats / Q000235:genetics; D008969:Molecular Sequence Data; D010933:Plankton / Q000382:microbiology; D012424:Rural Population; D012621:Seasons; D017422:Sequence Analysis, DNA; D014734:Vibrio cholerae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D041241:Vibrio cholerae O1 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D041242:Vibrio cholerae O139 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D044163:Vibrio cholerae non-O1 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification