Multilocus models in the infinite island model of population structure.
Different methods have been developed to consider the effects of statistical associations among genes that arise in population genetics models: kin selection models deal with associations among genes present in different interacting individuals, while multilocus models deal with associations among genes at different loci. It was pointed out recently that these two types of models are very similar in essence. In this paper, we present a method to construct multilocus models in the infinite island model of population structure (where deme size may be arbitrarily small). This method allows one to compute recursions on allele frequencies, and different types of genetic associations (including associations between different individuals from the same deme), and incorporates selection. Recursions can be simplified using quasi-equilibrium approximations; however, we show that quasi-equilibrium calculations for associations that are different from zero under neutrality must include a term that has not been previously considered. The method is illustrated using simple examples.
Roze
Denis
D
Station Biologique de Roscoff, CNRS, Adaptation et Diversité en Milieu Marin, Place Georges Teissier, BP 74, 29682 Roscoff Cedex, France. roze@sb-roscoff.fr
Rousset
François
F
D000818:Animals; D005075:Biological Evolution; D004171:Diploidy; D005787:Gene Frequency; D008040:Genetic Linkage; D005828:Genetics, Population; D006238:Haploidy; D008018:Life Cycle Stages; D008957:Models, Genetic; D011157:Population Dynamics; D040641:Quantitative Trait Loci; D012098:Reproduction / Q000502:physiology; D012641:Selection, Genetic