ENU mutagenesis in the mouse.
This unit describes the treatment of laboratory mice with the mutagen N-ethyl-N-nitrosourea (ENU) to achieve very highly induced rates of mutation throughout the genome. Further, it describes several popular mating schemes designed to produce animals displaying phenotypes associated with the induced mutations.
McDonald
J David
JD
Wichita State University, Wichita, Kansas, USA.
Beier
David
D
D000818:Animals; D005038:Ethylnitrosourea / Q000008:administration & dosage*; D008297:Male; D051379:Mice; D009153:Mutagens / Q000008:administration & dosage*; D009154:Mutation; D010641:Phenotype
D009153:Mutagens; D005038:Ethylnitrosourea