title: Comparison of effect of aerobic cycle training and progressive resistance training on walking ability after stroke: a randomized sham exercise-controlled study.
abstract: OBJECTIVE
  To determine whether changes in strength or cardiorespiratory fitness after exercise training improve walking ability in individuals who have had a stroke.
  
  
  METHODS
  A sham exercise-controlled, randomized two-by-two factorial design, in which the two factors investigated were cycle training (AEROBIC) and resistance training (STRENGTH).
  
  
  METHODS
  University exercise laboratory.
  
  
  METHODS
  Fifty-two individuals with a history of stroke (aged 63+/-9; time since stroke, 57+/-54 months).
  
  
  METHODS
  Participants undertook 30 exercise sessions over 10 to 12 weeks. Depending on group allocation, individuals underwent aerobic cycling plus sham progressive resistance training (PRT) (n=13), sham cycling plus PRT (n=13), aerobic cycling plus PRT (n=14), or sham cycling plus sham PRT (n=12).
  
  
  METHODS
  Primary outcomes were 6-minute walk distance, habitual and fast gait velocities, and stair climbing power. Secondary outcomes included measures of cardiorespiratory fitness; muscle strength, power, and endurance; and psychosocial attributes.
  
  
  RESULTS
  Neither AEROBIC nor STRENGTH improved walking distance or gait velocity significantly more than sham exercise, although STRENGTH significantly improved participants' stair climbing power by 17% (P=.009), as well as their muscle strength, power, and endurance; cycling peak power output; and self-efficacy. Conversely, AEROBIC improved indicators of cardiorespiratory fitness only. Cycling plus PRT produced larger effects than either single modality for mobility and impairment outcomes.
  
  
  CONCLUSIONS
  Single-modality exercises targeted at existing impairments do not optimally address the functional deficits of walking but do ameliorate the underlying impairments. The underlying cardiovascular and musculoskeletal impairments are significantly modifiable years after stroke with targeted robust exercise.
authors.affiliation: Faculty of Health Sciences, University of Sydney, Sydney, Australia.
authors.forename: Mi-Joung
authors.initials: MJ
authors.lastname: Lee
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Kilbreath
authors.forename: Maria Fiatarone
authors.initials: MF
authors.lastname: Singh
authors.forename: Brian
authors.initials: B
authors.lastname: Zeman
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Lord
authors.forename: Jacquelene
authors.initials: J
authors.lastname: Raymond
authors.forename: Glen M
authors.initials: GM
authors.lastname: Davis
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D001642:Bicycling; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D010809:Physical Fitness; D000071939:Stroke Rehabilitation; D016138:Walking