Identifying the "source" of recognition memory deficits in patients with Huntington's disease or Alzheimer's disease: evidence from the CVLT-II.
The present study compared the performance of individuals with Huntington's disease (HD) and Alzheimer's disease (AD) on three types of California Verbal Learning Test-Second Edition (CVLT-II) recognition discriminability indices (RDI): Source, Novel, and Total. The HD and AD groups did not differ significantly on Source RDI (all 16 targets versus the 16 previously presented, List B, distractors). However, HD patients performed significantly better than AD patients on Total RDI (all 16 targets versus all 32 distractors) and Novel RDI (all 16 targets versus 16 new distractors). Implications of these findings on the differentiation of the memory disorders associated with HD and AD are discussed.
Fine
Eric M
EM
Psychology Service (116B)-Delis Lab, Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. efine@ucsd.edu
Delis
Dean C
DC
Wetter
Spencer R
SR
Jacobson
Mark W
MW
Hamilton
Joanne M
JM
Peavy
Guerry
G
Goldstein
Jody
J
McDonald
Carrie
C
Corey-Bloom
Jody
J
Bondi
Mark W
MW
Salmon
David P
DP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications*; D004192:Discrimination, Psychological / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006816:Huntington Disease / Q000150:complications*; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology*; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D021641:Recognition, Psychology / Q000502:physiology*