Methods for cancer gene therapy.
First, the testing of therapeutic gene vectors in vitro is described. This is followed by a discussion of the administration of therapeutic vectors in vivo. Two methods for assessing the development of anti-tumor immunity after cytokine gene therapy are provided. In addition, two methods for the generation of murine tumor models in syngeneic hostsone subcutaneous and one orthotopicare also included.
Kwong
Y L
YL
Baylor College of Medicine, Houston, Texas, USA.
Chen
S H
SH
Woo
S L
SL
D000818:Animals; D045744:Cell Line, Tumor; D017930:Genes, Reporter; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D005826:Genetics, Medical; D006801:Humans; D007376:Interleukin-2 / Q000235:genetics; D051379:Mice; D009369:Neoplasms / Q000628:therapy*; D009374:Neoplasms, Experimental / Q000628:therapy; D013937:Thymidine Kinase / Q000235:genetics
D007376:Interleukin-2; D013937:Thymidine Kinase