title: Major hepatic resection for hilar cholangiocarcinoma without preoperative biliary drainage.
abstract: Hilar cholangiocarcinoma is a rare cancer in western countries but very high incidence in the northeast of Thailand. The only chance to cure is surgical resection. Preoperative biliary drainage (PBD) for improving liver function to decrease perioperative morbidity and mortality is claimed to be beneficial. To determine whether liver resection with hilar resection is a safe procedure in obstructive jaundice patients caused by hilar cholangiocarcinoma, the records of 30 consecutive patients undergoing surgery between May 1999 and May 2002 at Srinagarind hospital, Khon Kaen University, were retrospectively analyzed. Two patients died during hospitalization, an operative mortality of 6.7%. Survival was 33% at 1 year, 12% at 2 years,10% at 3 years and 6.7% at 4 years. In our experience, it is safe in most patients with obstructive jaundice due to hilar cholangiocarcinoma to perform liver resection without preoperative biliary drainage (PBD).
authors.affiliation: Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. nkhuntikeo@yahoo.com
authors.forename: Narong
authors.initials: N
authors.lastname: Khuntikeo
authors.forename: Ake
authors.initials: A
authors.lastname: Pugkhem
authors.forename: Vajarabhongsa
authors.initials: V
authors.lastname: Bhudhisawasdi
authors.forename: Thongueb
authors.initials: T
authors.lastname: Uttaravichien
mesh_terms: D001650:Bile Duct Neoplasms / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic / Q000601:surgery*; D001662:Biliary Tract Surgical Procedures; D018281:Cholangiocarcinoma / Q000601:surgery*; D004322:Drainage; D005260:Female; D006500:Hepatic Duct, Common / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis; D011300:Preoperative Care; D011379:Prognosis; D012189:Retrospective Studies