[IFN-alpha-induced psoriatic arthritis and HCV-related liver cirrhosis. Therapeutic options and patient's opinion].
Hepatitis C virus (HCV) infection in the setting of Psoriatic Arthritis is an additional variable to be considered in the therapeutic approach to the disease because of the complications of an immunosuppressive treatment in the course of a chronic infection and the possible hepatotoxicity of many drugs conventionally used to treat psoriatic arthritis. The case reported explores the therapeutic options in a patient with IFN-alpha-induced psoriatic arthritis, characterised by severe arthritis and psoriasis but also the concomitant presence of HCV chronic hepatitis, in light of the patient's concerns.
Cauli
A
A
Cattedra di Reumatologia II, Dipartimento di Scienze Mediche, Università degli Studi di Cagliari, Policlinico Universitario, 09042 Cagliari, Italia. cauli@pacs.unica.it
Porru
G
G
Vacca
A
A
Mameli
A
A
Ibba
V
V
Mura
V
V
Piga
M
M
Mathieu
A
A
D000998:Antiviral Agents / Q000009:adverse effects*; D015535:Arthritis, Psoriatic / Q000139:chemically induced*; D006526:Hepatitis C / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects*; D008103:Liver Cirrhosis / Q000188:drug therapy* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction
D000998:Antiviral Agents; D016898:Interferon-alpha