title: [Changes of platelet aggregation in cancer patients].
abstract: Aggregation function of platelets was investigated in 119 patients with breast cancer, 17--gastric cancer and 11--cancer of large bowel. Levels of spontaneous and induced aggregation were abnormally high thus contributing to thrombophilic potential. Also, they were a factor of tumor progression and metastatic spread. Risk of thrombotic complication can be reduced and survival improved by administration of antiaggregants.
authors.forename: A N
authors.initials: AN
authors.lastname: Shilova
authors.forename: E F
authors.initials: EF
authors.lastname: Kotovshchikova
authors.forename: A F
authors.initials: AF
authors.lastname: Lazarev
authors.forename: Z S
authors.initials: ZS
authors.lastname: Barkagan
authors.forename: E I
authors.initials: EI
authors.lastname: Buevich
mesh_terms: D001943:Breast Neoplasms / Q000097:blood; D003110:Colonic Neoplasms / Q000097:blood; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D010974:Platelet Aggregation; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D010976:Platelet Count; D013274:Stomach Neoplasms / Q000097:blood; D019851:Thrombophilia / Q000150:complications / Q000209:etiology*; D013927:Thrombosis / Q000209:etiology
chemical_list: D010975:Platelet Aggregation Inhibitors