title: Sono-thermal oxidation of dihydropyrimidinones.
abstract: Combination of ultrasound and heat has been used for the oxidation of some ethyl 3,4-dihydropyrimidin-2(1H)-one-5-carboxylates to their corresponding ethyl pyrimidin-2(1H)-one-5-carboxylates by using potassium peroxydisulfate in aqueous acetonitrile. An ultrasonic probe of 24 kHz frequency has been used for this study. Whereas the use of ultrasound increases the rate of reactions compared with reactions at reflux conditions, the nature of 4-substituent on the dihydropyrimidinone ring affects also the rate of reaction.
authors.affiliation: University of Isfahan, Faculty of Science, Department of Chemistry, 81746-73441 Isfahan, Iran. memarian@sci.ui.ac.ir
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Memarian
authors.forename: Asadollah
authors.initials: A
authors.lastname: Farhadi
mesh_terms: D006358:Hot Temperature; D007202:Indicators and Reagents; D016877:Oxidants; D010084:Oxidation-Reduction; D017680:Potassium Compounds / Q000737:chemistry; D011744:Pyrimidinones / Q000737:chemistry* / Q000528:radiation effects*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013431:Sulfates / Q000737:chemistry; D014465:Ultrasonics
chemical_list: D007202:Indicators and Reagents; D016877:Oxidants; D017680:Potassium Compounds; D011744:Pyrimidinones; D013431:Sulfates; C009007:potassium persulfate