title: Reversible deficit affecting the perception of tone of a human voice after tumour resection from the right auditory cortex.
abstract: We report on a young woman operated for a ganglioglioma involving the right auditory cortex (AC), presenting with auditory seizures. Despite a normal pre-operative examination, a specific post-operative disorder affecting the perception of a human voice occurred. The patient was unable to recognise the tone of familiar voices while she recognised the expressed content. A temporal lobectomy for recurrence was performed two years later. The patient recovered from the voice perception deficit. This report shows that (1) a discrete site within the AC is specifically involved in the perception of tone of the human voice (2) functional compensation is possible.
authors.affiliation: Department of Neurosurgery, University Hospital Hassan II, Fez, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: Benzagmout
authors.forename: M El F
authors.initials: Mel F
authors.lastname: Chaoui
authors.forename: H
authors.initials: H
authors.lastname: Duffau
mesh_terms: D038481:Anterior Temporal Lobectomy; D001303:Auditory Cortex / Q000503:physiopathology / Q000601:surgery*; D001308:Auditory Perceptual Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D004292:Dominance, Cerebral / Q000502:physiology*; D005500:Follow-Up Studies; D018303:Ganglioglioma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D020127:Recovery of Function / Q000502:physiology; D012086:Reoperation; D013061:Speech Acoustics; D014833:Voice Quality