title: [Impact of alcohol dependence on the course and psychopathology of schizophrenia].
abstract: OBJECTIVE
  The study was undertaken to investigate possible influence of alcoholism on the course and psychopathology of schizophrenia.
  
  
  METHODS
  A representative sample of 61 subjects was selected from schizophrenic patients with a history of alcohol dependence (dual diagnosis) registered in the period of 1997-2000. They were compared with 60 control patients with a single diagnosis of schizophrenia. In two groups, with the interview and clinical scales, the onset, course and psychopathology of schizophrenia were assessed.
  
  
  RESULTS
  Male patients with schizophrenia and alcohol dependence had a later mean age at onset of mental illness, women--a higher rate of alcohol abuse in the family compared to the control groups. In men with dual diagnosis, the negative symptoms were less prominent. Women with schizophrenia and alcohol dependence reported more depressive symptomatology.
authors.affiliation: Klinika Chorób Psychicznych AM w Białymstoku.
authors.forename: Beata
authors.initials: B
authors.lastname: Konarzewska
authors.forename: Regina
authors.initials: R
authors.lastname: Popławska
authors.forename: Beata
authors.initials: B
authors.lastname: Galińska
authors.forename: Agata
authors.initials: A
authors.lastname: Szulc
authors.forename: Tomasz
authors.initials: T
authors.lastname: Markowski
mesh_terms: D000328:Adult; D017668:Age of Onset; D000437:Alcoholism / Q000453:epidemiology*; D016022:Case-Control Studies; D015984:Causality; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012559:Schizophrenia / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D012737:Sex Factors