[State of microcirculation and endothelial dysfunction in patients with type 2 diabetes mellitus and arterial hypertension].
In order to evaluate microcirculation and endothelial dysfunction in type 2 diabetes mellitus accompanied by arterial hypertension, 40 men aged 54.9 +/- 1.49 years suffering from these conditions were examined using ultrasound continuous-wave microcirculation dopplerography (Minimax-Doppler-K) and ischemic test. The controls, 28 practically healthy persons, were sex- and age-comparable. Compared to the controls, the patients with diabetes and concomitant arterial hypertension displayed lower linear blood flow velocity both initially and during the postischemic period, their velocity parameters recovered after ischemic test more slowly, and the parameters of blood flow were rigid within the entire study. This could result from an increased microcirculatory blood vessel (arteriolar) diameter, changes in vessel reactivity, and the presence of endothelial dysfunction in these patients.
Volkov
V S
VS
Rudenko
E V
EV
D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008875:Middle Aged; D012720:Severity of Illness Index