title: [Genetic polymorphism for genes of alcohol dependence].
abstract: Alcohol dependence is a complex disorder which is influenced by physiological, psychological, environmental factors, individual inheritance and so on. Several candidate genes associated with alcohol dependence risk have been identified. The review focuses on several related genes that control alcohol metabolism such as alcohol dehydrogenase, aldehyde dehydrogenase, cytochrome P450 2E1 and regulate neurotransmission such as catechol-O-methyltransferase, dopamine receptors D2 and D4, and mu opioid receptor.
authors.affiliation: Department of Forensic Medicine, Kunming Medical College, Kunming 650031, China. hgf613817@163.com
authors.forename: Gen-Feng
authors.initials: GF
authors.lastname: He
authors.forename: Shu-Rong
authors.initials: SR
authors.lastname: Zhong
authors.forename: Qiang
authors.initials: Q
authors.lastname: Jing
mesh_terms: D000426:Alcohol Dehydrogenase / Q000235:genetics; D000437:Alcoholism / Q000235:genetics*; D000444:Aldehyde Dehydrogenase / Q000235:genetics; D002394:Catechol O-Methyltransferase / Q000235:genetics; D019392:Cytochrome P-450 CYP2E1 / Q000235:genetics; D006801:Humans; D011110:Polymorphism, Genetic / Q000235:genetics*; D017448:Receptors, Dopamine D2 / Q000235:genetics
chemical_list: D017448:Receptors, Dopamine D2; D000426:Alcohol Dehydrogenase; D019392:Cytochrome P-450 CYP2E1; D000444:Aldehyde Dehydrogenase; D002394:Catechol O-Methyltransferase