title: [How much liver resection is too much?].
abstract: Because the liver has a remarkable ability to regenerate, extensive resections are possible. Most liver centres recommend that the remnant liver after resection in a non-cirrhotic liver constitutes at least 30% of the normal liver mass. Too extensive resection carries a risk of the small-for-size syndrome with coagulapathy, jaundice, multi-organ failure and high mortality. Resection in a liver with established cirrhosis is more difficult because the ability to regenerate is lost and function is reduced. Portal hypertension is considered a contraindication to resection.
authors.affiliation: Arhus Universitetshospital, Arhus Sygehus, Medicinsk Hepato-gastroenterologisk Afdeling V, Arhus C. peott@as.aaa.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Ott
authors.forename: Frank V
authors.initials: FV
authors.lastname: Mortensen
mesh_terms: D000075202:Contraindications; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D008107:Liver Diseases / Q000601:surgery*; D008115:Liver Regeneration / Q000502:physiology*; D016031:Liver Transplantation / Q000502:physiology; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D012307:Risk Factors