Paradoxical response to levalbuterol.
Asthma is a common condition that can substantially affect patients' quality of life. Although several drugs, most commonly beta-adrenergic agonists, alleviate symptoms of asthma, they may cause paradoxical bronchospasm or paradoxical bronchoconstriction. Levalbuterol hydrochloride-a pure form of the (R)-stereoisomer in racemic albuterol-eliminates the adrenergic properties that can cause such adverse effects. However, we report a case of paradoxical bronchoconstriction in a 36-year-old man who was recently diagnosed as having new-onset asthma and was treated with levalbuterol.
Broski
Sarah E
SE
Pulmonary and Critical Care Department, Naval MedicalCenter San Diego, San Diego, Calif., USA.
Amundson
Dennis E
DE
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D000420:Albuterol / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000188:drug therapy*; D001982:Bronchial Diseases / Q000139:chemically induced*; D003251:Constriction, Pathologic / Q000139:chemically induced; D006801:Humans; D008297:Male; D036501:Metered Dose Inhalers
D000318:Adrenergic beta-Agonists; D000420:Albuterol