title: Bilateral vitreous hemorrhage in a child due to isolated platelet factor 3 availability defect.
abstract: Vitreous hemorrhage is an uncommon cause of decreased vision in children. We report a 3-year-old child with bilateral vitreous hemorrhage secondary to an isolated platelet factor 3 (PF-3) availability defect. Prophylactic infusion of platelet-rich plasma followed by pars plana vitrectomy in both eyes resulted in an excellent surgical and visual outcome. This report emphasizes the importance of exhaustive hematological and platelet function studies in a child presenting with bilateral vitreous hemorrhage and its implications on the management of present and future bleeding episodes.
authors.affiliation: Dr. R.P. Center for Ophthalmic Sciences, AIIMS, New Delhi, Delhi, India. drprashantnaithani@yahoo.co.in
authors.forename: Prashant
authors.initials: P
authors.lastname: Naithani
authors.forename: Abbas
authors.initials: A
authors.lastname: Mehrotra
authors.forename: Pradeep
authors.initials: P
authors.lastname: Venkatesh
authors.forename: Neeraj
authors.initials: N
authors.lastname: Wadhwa
authors.forename: Satpal
authors.initials: S
authors.lastname: Garg
mesh_terms: D001760:Bleeding Time; D001780:Blood Coagulation Tests; D002675:Child, Preschool; D005260:Female; D006801:Humans; D010314:Partial Thromboplastin Time; D010977:Platelet Factor 3 / Q000172:deficiency*; D010979:Platelet Function Tests; D014823:Vitreous Hemorrhage / Q000209:etiology*
chemical_list: D010977:Platelet Factor 3