title: Intravenous self-administration of ethanol in mice.
abstract: A more complete understanding of alcohols reinforcing actions is obtained when multiple behavioral procedures are used, some of which bypass taste factors. This unit describes a method for assessing the reinforcing effects of alcohol in mice using the most widely accepted procedure for assessing drug reward: intravenous self-administration.
authors.affiliation: Indiana University/Purdue University at Indianapolis, Indianapolis, Indiana, USA.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Grahame
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Cunningham
mesh_terms: D000818:Animals; D002404:Catheterization / Q000295:instrumentation / Q000379:methods; D003216:Conditioning, Operant / Q000187:drug effects / Q000502:physiology; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D007275:Injections, Intravenous / Q000379:methods; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D012054:Reinforcement, Psychology; D012646:Self Administration / Q000295:instrumentation / Q000379:methods*
chemical_list: D000431:Ethanol