title: Measurement of natural killer cell progenitor activity in culture.
abstract: Natural killer cells are morphologically related to and have progenitors in common with B and T lymphocytes. In this unit, protocols describe how to induce natural killer cell differentiation from prolymphocytes. Since NK cell differentiation cultures also support B cell differentiation, this protocol is extremely useful for seeking the B and NK cell branch point in their differentiation pathway.
authors.affiliation: Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
authors.forename: Taku
authors.initials: T
authors.lastname: Kouro
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yokota
authors.forename: Robert
authors.initials: R
authors.lastname: Welner
authors.forename: Paul W
authors.initials: PW
authors.lastname: Kincade
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D019411:Clinical Laboratory Techniques; D007694:Killer Cells, Natural / Q000166:cytology*; D051379:Mice; D013234:Stem Cells / Q000166:cytology*