[Acute transverse myelitis associated with coxsackievirus B---A retrospective analysis of 7 patients].
OBJECTIVE
Acute Transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic nerve dysfunction. There is often a clearly defined rostral border of sensory dysfunction. Nowadays, the pathogenesis of ATM is not clear. The present study aimed to understand possible relationship between ATM and infection with Coxsackievirus B.


METHODS
IgM antibody against Coxsackievirus B was detected in cerebrospinal fluid of 33 patients with ATM.


RESULTS
In 7 of the 33 cases with ATM, the IgM andtibody Coxsackievirus B (CVB) was positive. No infections with other pathogens were found at the onset of the disease.


CONCLUSIONS
The pathogenesis of ATM may involve infection with Coxsackievirus B.
Liu
Zhan-dong
ZD
Department of Neurology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050 China.
Wang
De-xin
DX
Feng
Zi-jing
ZJ
D000328:Adult; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid / Q000276:immunology; D029822:Enterovirus B, Human / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009188:Myelitis, Transverse / Q000134:cerebrospinal fluid / Q000276:immunology / Q000473:pathology / Q000821:virology*; D012189:Retrospective Studies
D000914:Antibodies, Viral; D007075:Immunoglobulin M