Intravenous self-administration of ethanol in mice.
A more complete understanding of alcohols reinforcing actions is obtained when multiple behavioral procedures are used, some of which bypass taste factors. This unit describes a method for assessing the reinforcing effects of alcohol in mice using the most widely accepted procedure for assessing drug reward: intravenous self-administration.
Grahame
Nicholas J
NJ
Indiana University/Purdue University at Indianapolis, Indianapolis, Indiana, USA.
Cunningham
Christopher L
CL
D000818:Animals; D002404:Catheterization / Q000295:instrumentation / Q000379:methods; D003216:Conditioning, Operant / Q000187:drug effects / Q000502:physiology; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D007275:Injections, Intravenous / Q000379:methods; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D012054:Reinforcement, Psychology; D012646:Self Administration / Q000295:instrumentation / Q000379:methods*
D000431:Ethanol