title: Targeting the prevention of plaque rupture as a new strategy for prevention of acute arterial cardiovascular events.
authors.forename: Marcel
authors.initials: M
authors.lastname: Levi
authors.forename: Erik
authors.initials: E
authors.lastname: Stroes
mesh_terms: D000208:Acute Disease; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D050197:Atherosclerosis / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology; D002318:Cardiovascular Diseases / Q000201:enzymology / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D018836:Inflammation Mediators / Q000378:metabolism; D051379:Mice; D009336:Necrosis; D018384:Oxidative Stress / Q000187:drug effects; D000071137:Poly (ADP-Ribose) Polymerase-1; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D012421:Rupture
chemical_list: D004791:Enzyme Inhibitors; D018836:Inflammation Mediators; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; C499321:Parp1 protein, mouse; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases