Diagnostic performance of a new automated heterophile antibody test in adults and children.
Epstein-Barr virus serologic profiles were obtained from 618 patients using an automated platform, including the new BioPlex heterophile assay. When compared with 2 IgM viral capsid antigen (VCA) assays and a predicate heterophile assay, the BioPlex heterophile assay was more likely to be associated with serologic patterns of acute infection.
Klutts
J Stacey
JS
University of Iowa Carver College of Medicine, Veterans Affairs Medical Center, Iowa City, IA 52246, USA. stacey-klutts@uiowa.edu
Wu
Alan H B
AH
Smith
Andrew
A
Yen-Lieberman
Belinda
B
Gronowski
Ann M
AM
D000293:Adolescent; D000328:Adult; D000910:Antibodies, Heterophile; D000914:Antibodies, Viral / Q000097:blood*; D001331:Automation; D002648:Child; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007118:Immunoassay / Q000379:methods*
D000910:Antibodies, Heterophile; D000914:Antibodies, Viral