Use of the TIMI frame count in the assessment of coronary artery blood flow and microvascular function over the past 15 years.
Since its introduction, the TIMI frame count method has contributed to the understanding of the pathophysiology of coronary artery disease. In this article, the evolution of the TFC method and its applicability in the assessment of various therapeutic modalities are described.
Kunadian
Vijayalakshmi
V
Cardiovascular Divisions, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Harrigan
Caitlin
C
Zorkun
Cafer
C
Palmer
Alexandra M
AM
Ogando
Katherine J
KJ
Biller
Leah H
LH
Lord
Erin E
EE
Williams
Scott P
SP
Lew
Michelle E
ME
Ciaglo
Lauren N
LN
Buros
Jacqueline L
JL
Marble
Susan J
SJ
Gibson
William J
WJ
Gibson
C Michael
CM
D017023:Coronary Angiography / Q000266:history / Q000379:methods*; D003324:Coronary Artery Disease / Q000175:diagnosis*; D003326:Coronary Circulation; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008833:Microcirculation