title: Comparison of 18F-FDG PET and MRI in assessment of uterine smooth muscle tumors.
abstract: The purpose of this study was to prospectively determine whether combined MRI and (18)F-FDG PET is more accurate than MRI in assessing nonbenign uterine smooth muscle tumors (USMTs).
  
  
  METHODS
  Seventy patients (mean age, 49+/-10 y; range, 28-77 y) suspected of having nonbenign USMTs underwent both MRI and (18)F-FDG PET before surgery. Results were evaluated using receiver-operating-characteristic (ROC) analyses and the Cochran Q test.
  
  
  RESULTS
  The area under the ROC curve for MRI with (18)F-FDG PET was significantly higher than that for MRI (0.97 vs. 0.89, P<0.05). Although multiple comparisons using the Cochran Q test were not significant, the sensitivity, specificity, and accuracy for MRI with (18)F-FDG PET with probable nonbenign USMT cases considered to be positive were higher than those for MRI (93.3% vs. 73.3%; 92.7% vs. 85.5%; and 92.9% vs. 82.9%, respectively).
  
  
  CONCLUSIONS
  MRI with (18)F-FDG PET is useful in assessing nonbenign USMTs, as compared with MRI.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Eihaiji-cho, Yoshida-gun, Fukui Prefecture, Japan. yyoshida@u-fukui.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sawamura
authors.forename: Akiko
authors.initials: A
authors.lastname: Shinagawa
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tsujikawa
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Okazawa
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Tsuchida
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Imamura
authors.forename: Narufumi
authors.initials: N
authors.lastname: Suganuma
authors.forename: Fumikazu
authors.initials: F
authors.lastname: Kotsuji
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009215:Myometrium / Q000000981:diagnostic imaging / Q000473:pathology*; D049268:Positron-Emission Tomography / Q000379:methods*; D012680:Sensitivity and Specificity; D018235:Smooth Muscle Tumor / Q000000981:diagnostic imaging*
chemical_list: D019788:Fluorodeoxyglucose F18