title: Hemarthrosis due to a rare cause of hemorrhagic diathesis: Ehlers-Danlos syndrome.
abstract: The authors report a case of hemarthrosis complicated by severe anemia related to a congenital connective tissue disease: Ehlers-Danlos syndrome. A boy fell down and suffered tumefaction of both knees with bilateral rupture of the rotula tendon. He underwent surgical reinsertion of each tendon on the rotula. He later showed an unexpected ongoing hematic effusion, with severe anemia. He was screened for coagulation disorders with no results. On taking a more detailed history and investigating the patient's phenotypical features, the authors diagnosed Ehlers-Danlos syndrome, hypermobile variant. The hemarthrosis and anemia were thus concluded to be consequences of excessive tissue fragility due to a congenital connective tissue disease.
authors.affiliation: Dipartimento di Biomedicina dell'età evolutiva, Bari University, Bari, Italy. giordano@bioetaev.uniba.it
authors.forename: Paola
authors.initials: P
authors.lastname: Giordano
authors.forename: Giovanni Carlo
authors.initials: GC
authors.lastname: Del Vecchio
authors.forename: Rosanna
authors.initials: R
authors.lastname: Scaraggi
authors.forename: Fabio
authors.initials: F
authors.lastname: Cardinale
authors.forename: Biagio
authors.initials: B
authors.lastname: Moretti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lassandro
authors.forename: Domenico
authors.initials: D
authors.lastname: De Mattia
mesh_terms: D000058:Accidental Falls; D000293:Adolescent; D000740:Anemia / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D004535:Ehlers-Danlos Syndrome / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006395:Hemarthrosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D012421:Rupture / Q000473:pathology / Q000601:surgery; D013708:Tendon Injuries / Q000473:pathology / Q000601:surgery; D013710:Tendons / Q000473:pathology / Q000601:surgery