Affective and psychiatric disorders in celiac disease.
Several extraintestinal clinical manifestations have been reported in celiac disease (CD). Among them, growing evidence suggests the association between CD and affective and psychiatric disorders. In this review the most frequent affective and psychiatric disorders associated with CD and the possible mechanisms involved in these associations were analyzed. The available data suggest that screening for CD in patients with affective and/or psychiatric symptoms may be useful since these disorders could be the expression of an organic disease rather than primary psychiatric illnesses.
Addolorato
Giovanni
G
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy. g.addolorato@rm.unicatt.it
Leggio
Lorenzo
L
D'Angelo
Cristina
C
Mirijello
Antonio
A
Ferrulli
Anna
A
Cardone
Silvia
S
Vonghia
Luisa
L
Abenavoli
Ludovico
L
Leso
Veruscka
V
Nesci
Antonio
A
Piano
Salvatore
S
Capristo
Esmeralda
E
Gasbarrini
Giovanni
G
D002446:Celiac Disease / Q000150:complications / Q000523:psychology*; D006801:Humans; D001523:Mental Disorders / Q000209:etiology*