[Uterine artery embolisation in the treatment of uterine fibroids: outcomes of randomised trials].
In the past so years, uterine artery embolisation has gained popularity in the treatment of uterine fibroids compared with traditional surgical interventions. This was based on promising results from a few non-randomised studies, which reported success rates of 95 to 98%. Were these rates accurate? Two recent randomised studies (the Dutch EMMY trial and the Scottish REST trial) showed that, in patients with symptomatic uterine fibroids, the time to recovery and return to work was significantly shorter after embolisation than after surgery (hysterectomy or myomectomy). However, embolisation was insufficiently effective in approximately 20% of patients, who required further treatment. Despite this, quality of life after one and two years in both treatment arms were identical. Embolisation, therefore, may be a valid treatment alternative in patients with symptomatic fibroids who are candidates for hysterectomy.
Hehenkamp
W J K
WJ
Afd. Verloskunde en Gynaecologie, Academisch Medisch Centrum/Universiteit van Amsterdam, Amsterdam.
Volkers
N A
NA
Birnie
E
E
Reekers
J A
JA
Ankum
W M
WM
D001158:Arteries; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000628:therapy*; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D014599:Uterus / Q000098:blood supply*