title: Aortic valve endocarditis due to abiotrophia defectiva: a rare etiology.
abstract: Abiotrophia defectiva is a rare cause of infective endocarditis. Besides an association with often negative blood cultures and difficult treatment, high rates of relapse and higher mortality than endocarditis caused by other viridans streptococci are known features of this entity. We report on the surgical and medical management of the aortic valve endocarditis caused by Abiotrophia defectiva in a 19-year-old patient. To the best of our knowledge, this is the first case of a patient to have Down syndrome and Abiotrophia defectiva endocarditis requiring aortic valve replacement.
authors.affiliation: Department of Cardiac Surgery, Medical Faculty, University of Rostock, Rostock, Germany. can.yerebakan@med.uni-rostock.de
authors.forename: Can
authors.initials: C
authors.lastname: Yerebakan
authors.forename: Bernd
authors.initials: B
authors.lastname: Westphal
authors.forename: Christian
authors.initials: C
authors.lastname: Skrabal
authors.forename: Alexander
authors.initials: A
authors.lastname: Kaminski
authors.forename: Murat
authors.initials: M
authors.lastname: Ugurlucan
authors.forename: Anne-Kathrin
authors.initials: AK
authors.lastname: Bomke
authors.forename: Andreas
authors.initials: A
authors.lastname: Liebold
authors.forename: Gustav
authors.initials: G
authors.lastname: Steinhoff
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001021:Aortic Valve / Q000382:microbiology / Q000601:surgery; D001705:Bioprosthesis; D004269:DNA, Bacterial / Q000032:analysis; D004314:Down Syndrome / Q000150:complications; D004359:Drug Therapy, Combination; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D005500:Follow-Up Studies; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D010406:Penicillins / Q000008:administration & dosage / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D005839:Gentamicins; D010406:Penicillins