Narrative review: paroxysmal nocturnal hemoglobinuria: the physiology of complement-related hemolytic anemia.
Brodsky
Robert A
RA
Division of Hematology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205-2196, USA. brodsro@jhmi.edu
D000328:Adult; D000743:Anemia, Hemolytic / Q000150:complications / Q000503:physiopathology*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D003165:Complement System Proteins / Q000502:physiology*; D004421:Dystonia / Q000209:etiology; D017261:Glycosylphosphatidylinositols / Q000235:genetics / Q000502:physiology; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology; D009154:Mutation; D013927:Thrombosis / Q000209:etiology
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D017261:Glycosylphosphatidylinositols; D008565:Membrane Proteins; C080086:phosphatidylinositol glycan-class A protein; D003165:Complement System Proteins; C481642:eculizumab