title: Short communication: apoptosis regulates passive immune transfer in newborn kids.
abstract: Ten newborn kids were used to evaluate the relationship between apoptosis and passive immune transfer in neonatal enterocytes. Kids were slaughtered in groups of 2 at birth, 1, 2, 3, or 60 d postpartum, and samples of duodenal epithelium collected from each animal. Samples were fixed, dehydrated, and embedded in paraffin wax. Sections were assessed for apoptotic cells and immunostained for IgG. Our results suggest that IgG absorption is mediated by apoptotic enterocytes. Thus, delaying apoptosis may improve the success of passive immune transfer.
authors.affiliation: Department of Morphology, Las Palmas de Gran Canaria University, Arucas 35413, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Castro-Alonso
authors.forename: N
authors.initials: N
authors.lastname: Castro
authors.forename: J
authors.initials: J
authors.lastname: Capote
authors.forename: A
authors.initials: A
authors.lastname: Morales-delaNuez
authors.forename: I
authors.initials: I
authors.lastname: Moreno-Indias
authors.forename: D
authors.initials: D
authors.lastname: Sánchez-Macias
authors.forename: P
authors.initials: P
authors.lastname: Herraez
authors.forename: A
authors.initials: A
authors.lastname: Argüello
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D017209:Apoptosis / Q000276:immunology*; D004386:Duodenum / Q000166:cytology; D020895:Enterocytes / Q000166:cytology / Q000276:immunology; D004847:Epithelial Cells / Q000166:cytology / Q000276:immunology; D006041:Goats / Q000276:immunology*; D007112:Immunity, Maternally-Acquired / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D020287:In Situ Nick-End Labeling; D008297:Male
chemical_list: D007074:Immunoglobulin G