Downregulation of hepatic acetylation of drugs in chronic renal failure.
Simard
Emilie
E
Service de néphrologie et Centre de recherche de l'Hôpital Maisonneuve-Rosemont, Université de Montréal, Montréal, Canada.
Naud
Judith
J
Michaud
Josée
J
Leblond
Francois A
FA
Bonnardeaux
Alain
A
Guillemette
Chantal
C
Sim
Edith
E
Pichette
Vincent
V
D010129:4-Aminobenzoic Acid / Q000378:metabolism; D000107:Acetylation; D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000235:genetics / Q000378:metabolism*; D001835:Body Weight / Q000502:physiology; D015536:Down-Regulation; D015870:Gene Expression; D022781:Hepatocytes / Q000201:enzymology; D008658:Inactivation, Metabolic / Q000502:physiology*; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010281:Parathyroid Hormone / Q000378:metabolism; D016105:Parathyroidectomy; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D014511:Uremia / Q000097:blood
D007527:Isoenzymes; D010281:Parathyroid Hormone; D012333:RNA, Messenger; D001191:Arylamine N-Acetyltransferase; C089384:N-acetyltransferase 1; D010129:4-Aminobenzoic Acid