title: [Acute renal function deterioration in a Coronary Unit in Spain].
abstract: OBJECTIVE
  To assess the incidence and prognostic value of acute renal function deterioration (ARFD) in patients with acute heart disease.
  
  
  METHODS
  Coronary Care Unit in a tertiary university hospital.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  One hundred consecutive patients admitted during 2004.
  
  
  METHODS
  No randomized interventions were done. Diagnostic and therapeutic procedures were performed according to local protocols and current Clinical Practice Guidelines. PRIMARY VARIABLES: The primary aim of the study was to analyze the incidence of acute renal function deterioration and its effect in mortality during hospitalization. ARFD was defined as the increase of serum creatinine by 0.5 mg/dl and/or by 50% over baseline.
  
  
  RESULTS
  Incidence of ARFD was 26%, with a mean increase of serum creatinine of 1.5 +/- 0.9 mg/dl. ARFD was significantly associated with age, background of hypertension and chronic kidney disease. Patients with ARFD had a more complicated course, longer hospitalizations, and received fewer catheterisms. Acute renal function deterioration was associated with higher mortality during hospitalization (33% versus 6%, p = 0.002).
  
  
  CONCLUSIONS
  Acute renal function deterioration is frequent in patients with acute heart disease and its presence is linked with higher mortality.
authors.affiliation: Servicio de Cardiología, Hospital Ramón y Cajal, Madrid, España. docalcala@hotmail.com
authors.forename: D
authors.initials: D
authors.lastname: Martí
authors.forename: C
authors.initials: C
authors.lastname: Escobar
authors.forename: N
authors.initials: N
authors.lastname: Dedieu
authors.forename: F
authors.initials: F
authors.lastname: Liaño
authors.forename: M
authors.initials: M
authors.lastname: Jiménez Mena
authors.forename: E
authors.initials: E
authors.lastname: Asín
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000534:rehabilitation*; D000368:Aged; D015897:Comorbidity; D003325:Coronary Care Units / Q000706:statistics & numerical data*; D003327:Coronary Disease / Q000453:epidemiology* / Q000534:rehabilitation*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology