title: Synthesis of spacer-containing analogs of serogroup 6 pneumococcal oligosaccharides.
abstract: An efficient convergent strategy for the synthesis of a range of spacer-containing pneumococcal oligosaccharides of serogroup 6 and derivatives thereof has been developed. The spacer-containing oligosaccharides were deprotected and are available for subsequent conjugation and immunological studies, which are underway in our laboratory.
authors.affiliation: Department of Chemistry and Biochemistry, University of Missouri, St Louis, One University Boulevard, St Louis, MO 63121, USA.
authors.forename: Archana R
authors.initials: AR
authors.lastname: Parameswar
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Hasty
authors.forename: Alexei V
authors.initials: AV
authors.lastname: Demchenko
mesh_terms: D002240:Carbohydrate Sequence; D009844:Oligosaccharides / Q000138:chemical synthesis*; D013296:Streptococcus pneumoniae / Q000737:chemistry* / Q000276:immunology
chemical_list: D009844:Oligosaccharides