title: Naturally acquired human Plasmodium knowlesi infection, Singapore.
abstract: We report a case of naturally acquired Plasmodium knowlesi in Singapore, a malaria-free country. Diagnosis was confirmed by PCR with validated species-specific primers. In industrialized countries, free-ranging primates are a potential source of P. knowlesi human infection. P. knowlesi infection is a differential diagnosis of febrile illness acquired in Singapore.
authors.affiliation: Department of Infectious Disease, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. oon_tek_ng@ttsh.com.sg
authors.forename: Oon Tek
authors.initials: OT
authors.lastname: Ng
authors.forename: Eng Eong
authors.initials: EE
authors.lastname: Ooi
authors.forename: Cheng Chuan
authors.initials: CC
authors.lastname: Lee
authors.forename: Piao Jarrod
authors.initials: PJ
authors.lastname: Lee
authors.forename: Lee Ching
authors.initials: LC
authors.lastname: Ng
authors.forename: Sze Wong
authors.initials: SW
authors.lastname: Pei
authors.forename: Tian Ming
authors.initials: TM
authors.lastname: Tu
authors.forename: Jin Phang
authors.initials: JP
authors.lastname: Loh
authors.forename: Yee Sin
authors.initials: YS
authors.lastname: Leo
mesh_terms: D000328:Adult; D000818:Animals; D017931:DNA Primers; D016054:DNA, Protozoan / Q000032:analysis; D003937:Diagnosis, Differential; D005334:Fever / Q000175:diagnosis; D006801:Humans; D008251:Macaca / Q000469:parasitology; D008288:Malaria / Q000175:diagnosis* / Q000469:parasitology / Q000635:transmission*; D008297:Male; D008992:Monkey Diseases / Q000469:parasitology / Q000635:transmission*; D016790:Plasmodium knowlesi / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000379:methods; D012846:Singapore / Q000453:epidemiology; D013045:Species Specificity; D015047:Zoonoses / Q000469:parasitology / Q000635:transmission*
chemical_list: D017931:DNA Primers; D016054:DNA, Protozoan