title: Prostate cancer stem cell therapy: hype or hope?
abstract: The stem cell concept of cancer suggests that each cancer contains a small fraction of stem cells responsible for the maintenance and progression of the disease. The implication of this concept is that by targeting and killing the cancer stem cells, it may be possible to improve survival or even cure the disease. Prostate cancer stem cell therapy is a valid goal to aim for, but there are massive hurdles to overcome, even if the concept is shown to be correct.
authors.affiliation: Department of Surgery, Prostate Cancer Research Centre, University College London, London, UK. j.masters@ucl.ac.uk
authors.forename: J R
authors.initials: JR
authors.lastname: Masters
authors.forename: C
authors.initials: C
authors.lastname: Kane
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Ahmed
mesh_terms: D000818:Animals; D018450:Disease Progression; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000378:metabolism / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D033581:Stem Cell Transplantation; D016896:Treatment Outcome