[Liver resection over the last decade].
OBJECTIVE
The results after liver resection have improved over the last decade with an operative mortality rate of less than 5% in high-volume centres. The aim of the present study was to assess the perioperative outcome after hepatic resection and to assess the long-term survival after liver resection of hepatic metastases from colorectal cancer and hepatocellular carcinoma in our institution.


METHODS
The patients who underwent their primary liver resection from 1.1.1995-31.12.2004 in our institution were included. The surgical outcome was reviewed retrospectively and the five-year survival after resection of hepatic metastases from colorectal cancer and hepatocellular carcinoma was estimated.


RESULTS
141 patients (71M/70F), median age 58 years (1-78), underwent a liver resection in the ten-year period. The number of resections increased from two in 1995 to 32 in 2004. Median hospital stay was 9 days (3-38). The most frequent complication was biliary leakage (7.8%), haemorrhage (2.8%) and hepatic insufficiency (2.8%). 30-days mortality was 1.4%. The actuarial 5-survival after hepatic resection for colorectal liver metastases and hepatocellular carcinoma was 39% and 42%, respectively.


CONCLUSIONS
The morbidity and mortality rate after hepatic resection and the long-term survival for patients undergoing resection for hepatic metastases from colorectal cancer and hepatocellular carcinoma in our institution are comparable with the best high-volume centres.
Wettergren
André
A
Rigshospitalet, Kirurgisk Afdeling CTX, København Ø. wettergren@dadlnet.dk
Larsen
Peter N
PN
Rasmussen
Allan
A
Hillingsø
Jens G
JG
Kirkegaard
Preben
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D015179:Colorectal Neoplasms / Q000473:pathology; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007223:Infant; D008099:Liver / Q000601:surgery*; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome