title: Introduction to comparing large sequence sets.
abstract: Comparisons of whole genomes can yield important insights into the evolution of genome structure, such as the role of inversions in bacterial evolution and the identification of large-scale duplications in the human genome. This unit briefly compares two tools for aligning whole genome sequences: MUMmer and PipMaker. These tools differ in both the underlying algorithms used, and in the interface they present to the user.
authors.affiliation: University of Glasgow, Glasgow, Scotland.
authors.forename: Roderic D M
authors.initials: RD
authors.lastname: Page
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D002874:Chromosome Mapping / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods; D011381:Programming Languages; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software