title: [Combined liver resection and radiofrequency ablation for colorectal liver metastases].
abstract: BACKGROUND
  Liver resection in combination with radiofrequency ablation (RFA) is a novel approach in patients with colorectal liver metastases who are otherwise unresectable.
  
  
  METHODS
  Eighteen patients with colorectal liver metastases were treated with surgical resection combined with RFA. All patients were followed prospectively with CT-scanning of thorax and abdomen during a 5-year period, 1, 4, 8 and 12 months after treatment and every 6 months thereafter for the following 4 years. Main outcome was recurrence and survival.
  
  
  RESULTS
  Eleven male and 7 female patients with a median age of 65 years (41-78) were treated with combined surgery and RFA. 76 metastases were treated, 34 of these with resection. The median survival rate in the entire group was 35 months. 5-years overall survival was 34%. 12 patients had recurrence and were treated with multimodality therapy.
  
  
  CONCLUSIONS
  Combined surgery and RFA treatment was a good alternative in a group of patients with colorectal liver metastases that were otherwise only suitable for systemic chemotherapy.
authors.affiliation: Arhus Universitetshospital, Arhus Sygehus, Kirurgisk Gastroenterologisk Afdeling L, Arhus. askannerup@gmail.com
authors.forename: Anne-Sofie
authors.initials: AS
authors.lastname: Kannerup
authors.forename: Dennis Tømrer
authors.initials: DT
authors.lastname: Nielsen
authors.forename: Steen Mellerup
authors.initials: SM
authors.lastname: Sørensen
authors.forename: Frank Viborg
authors.initials: FV
authors.lastname: Mortensen
mesh_terms: D000328:Adult; D000368:Aged; D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011446:Prospective Studies; D016019:Survival Analysis