title: Cytokine, growth factor, and chemokine ligand database.
abstract: Cytokines, chemokines, and growth factors are soluble proteins produced by leukocytes and other cell types, which act as chemical communicators between cells and tissues within the body. These proteins mediate a number of functions, ranging from effects on cell growth, differentiation, survival, and a number of effector activities. The main purpose of this unit is to provide an easy-to-use reference summarizing some of the current information on well-established cytokine, growth factore, and chemokine ligands. The information provided is confined largely to alternative names, protein properties, genetic chracteristics, chromosomal localization, cellular expression patters, cellular-tissue targets, stimuli regulating expression, functional properties, expression analysis, and clinical utility.
authors.affiliation: Laboratory of Immunology, Baltimore, MD, USA.
authors.forename: Dennis D
authors.initials: DD
authors.lastname: Taub
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology; D002470:Cell Survival / Q000502:physiology; D018925:Chemokines / Q000145:classification* / Q000235:genetics* / Q000378:metabolism*; D002875:Chromosomes / Q000235:genetics; D016208:Databases, Factual; D005786:Gene Expression Regulation / Q000502:physiology; D006801:Humans; D008024:Ligands
chemical_list: D018925:Chemokines; D008024:Ligands