Pseudo-Gaucher cells in multiple myeloma.
A case of multiple myeloma is reported in which the bone marrow contained sheets of histiocytes with light microscopic features mimicking Gaucher cells. The patient had no clinical evidence of inherited Gaucher's disease. These pseudo-Gaucher cells obscured neoplastic plasma cells causing diagnostic difficulty.
Shenjere
Patrick
P
Department of Histopathology, Christie Hospital NHS Foundation Trust, Manchester, United Kingdom. patrick.shenjere@christie.nhs.uk
Roy
Ashok
A
Eyden
Brian
B
Banerjee
Saumitra S
SS
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001854:Bone Marrow Cells / Q000473:pathology*; D003907:Dexamethasone / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005776:Gaucher Disease / Q000175:diagnosis*; D006644:Histiocytes / Q000473:pathology*; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000188:drug therapy; D010950:Plasma Cells / Q000473:pathology
D003907:Dexamethasone; D015255:Idarubicin