[Progress of researches on drug-loaded nanoparticles].
The progress of researches on drug-loaded nanoparticles was summarized in this review. The major emphasis was laid on the selection of wall polymers, technology of preparation, surface modification, investigation of release in vitro and biocompatibility evaluation. Additionally, we envisioned a perspective regarding the development in this field. With the development of synthesis of biodegradable polymer, with the appearance of novel equipment, and with the deep-going studies on modification of nanoparticles surface method, on fabrication of nanoparticles art as well as on evaluation of drug release and reaction between drug and organ, further researches in this field will open up the way to applications of drug-loaded nanoparticles in larger field.
Zhao
Jian
J
Engineering Research Center for Biomedical Materials under Ministry of Education, East China University of Science and Technology, Shanghai 200237, China.
Sheng
Yan
Y
Shan
Xiaoqian
X
Zhang
Xiaolan
X
Yuan
Yuan
Y
Liu
Changsheng
C
D002214:Capsules / Q000008:administration & dosage; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry* / Q000493:pharmacokinetics; D004339:Drug Compounding / Q000639:trends*; D050997:Nanomedicine / Q000639:trends*; D053758:Nanoparticles / Q000008:administration & dosage / Q000737:chemistry*; D011091:Polyesters / Q000737:chemistry
D002214:Capsules; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D011091:Polyesters; C033616:poly(lactide)