title: Imaging of breast cancer with mid- and long-wave infrared camera.
abstract: In this novel study the breasts of 15 women with palpable breast cancer were preoperatively imaged with three technically different infrared (IR) cameras - micro bolometer (MB), quantum well (QWIP) and photo voltaic (PV) - to compare their ability to differentiate breast cancer from normal tissue. The IR images were processed, the data for frequency analysis were collected from dynamic IR images by pixel-based analysis and from each image selectively windowed regional analysis was carried out, based on angiogenesis and nitric oxide production of cancer tissue causing vasomotor and cardiogenic frequency differences compared to normal tissue. Our results show that the GaAs QWIP camera and the InSb PV camera demonstrate the frequency difference between normal and cancerous breast tissue; the PV camera more clearly. With selected image processing operations more detailed frequency analyses could be applied to the suspicious area. The MB camera was not suitable for tissue differentiation, as the difference between noise and effective signal was unsatisfactory.
authors.affiliation: Tampere University Hospital, Medical Imaging Centre, Tampere, Finland. risto.joro@fma.fi
authors.forename: R
authors.initials: R
authors.lastname: Joro
authors.forename: A-L
authors.initials: AL
authors.lastname: Lääperi
authors.forename: P
authors.initials: P
authors.lastname: Dastidar
authors.forename: S
authors.initials: S
authors.lastname: Soimakallio
authors.forename: T
authors.initials: T
authors.lastname: Kuukasjärvi
authors.forename: T
authors.initials: T
authors.lastname: Toivonen
authors.forename: R
authors.initials: R
authors.lastname: Saaristo
authors.forename: R
authors.initials: R
authors.lastname: Järvenpää
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000175:diagnosis*; D003952:Diagnostic Imaging / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D007259:Infrared Rays; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013055:Spectrophotometry, Infrared / Q000295:instrumentation*; D013817:Thermography / Q000295:instrumentation*