title: How chemotherapy damages the central nervous system.
abstract: Chemotherapy adversely affects cognitive function both acutely and chronically, but little is known about the underlying mechanisms. A new study shows that short-term chemotherapy causes not only acute injury to progenitor cells, but also delayed damage to myelin.
authors.affiliation: Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 431, Houston, TX 77030, USA. cameyers@mdanderson.org
authors.forename: Christina A
authors.initials: CA
authors.lastname: Meyers
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002490:Central Nervous System / Q000187:drug effects* / Q000473:pathology; D003071:Cognition / Q000187:drug effects*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009186:Myelin Sheath / Q000378:metabolism*
chemical_list: D000970:Antineoplastic Agents