Apoptosis pathways in fungal growth, development and ageing.
Apoptosis is one type of programmed cell death with great importance for development and homeostasis of multicellular organisms. Unexpectedly, during the past decade, evidence has been obtained for the existence of a basal apoptosis machinery in yeast, as unicellular fungus, and in some filamentous fungi, a group of microorganisms that are neither true unicellular nor true multicellular biological systems but something in between. Here, we review evidence for a role of apoptotic processes in fungal pathogenicity, competitiveness, propagation, ageing and lifespan control.
Hamann
Andrea
A
Institute for Molecular Biosciences, Department of Biosciences and Cluster of Excellence Macromolecular Complexes, J.W. Goethe-University, Max-von-Laue-Strasse 9, Frankfurt, Germany.
Brust
Diana
D
Osiewacz
Heinz D
HD
D017209:Apoptosis; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D005658:Fungi / Q000254:growth & development* / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D054884:Host-Pathogen Interactions; D006801:Humans; D016897:Respiratory Burst; D015398:Signal Transduction
D005656:Fungal Proteins