Synthesis of spacer-containing analogs of serogroup 6 pneumococcal oligosaccharides.
An efficient convergent strategy for the synthesis of a range of spacer-containing pneumococcal oligosaccharides of serogroup 6 and derivatives thereof has been developed. The spacer-containing oligosaccharides were deprotected and are available for subsequent conjugation and immunological studies, which are underway in our laboratory.
Parameswar
Archana R
AR
Department of Chemistry and Biochemistry, University of Missouri, St Louis, One University Boulevard, St Louis, MO 63121, USA.
Hasty
Scott J
SJ
Demchenko
Alexei V
AV
D002240:Carbohydrate Sequence; D009844:Oligosaccharides / Q000138:chemical synthesis*; D013296:Streptococcus pneumoniae / Q000737:chemistry* / Q000276:immunology
D009844:Oligosaccharides