Postoperative muscle weakness in a patient recently treated with infliximab.
We present a case of profound postoperative muscle weakness in a patient who had been treated with infliximab, and whose weakness had not manifested pre-operatively. We believe this to be the first case report of infliximab-related muscle weakness manifesting immediately after anaesthesia.
Drummond
A D
AD
Department of Anaesthesia, Calderdale Royal Hospital, Salterhebble, Halifax HX3 0PW, UK. dr.andy.drummond@googlemail.com
Williamson
R M
RM
Silverdale
M A
MA
Rothwell
M P
MP
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D003424:Crohn Disease / Q000188:drug therapy; D005260:Female; D006801:Humans; D000069285:Infliximab; D018908:Muscle Weakness / Q000139:chemically induced*; D011183:Postoperative Complications / Q000139:chemically induced*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab