title: Expression of microRNAs during embryonic development of Xenopus tropicalis.
abstract: microRNAs (miRNAs) are short, non-coding RNAs that regulate gene expression and have prominent roles during early embryo development and organogenesis. We set out to determine the expression pattern of miRNAs in the developmental model system, Xenopus tropicalis. We made probes to predicted primary-miRNA transcripts and performed in situ hybridization. Our data show conserved and novel tissue-specific expression patterns during embryogenesis that suggest functional roles during development.
authors.affiliation: Department of Molecular and Cell Biology, 579 Life Sciences Addition, University of California, Berkeley, CA 94720-3200, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Walker
authors.forename: Richard M
authors.initials: RM
authors.lastname: Harland
mesh_terms: D000818:Animals; D004625:Embryo, Nonmammalian / Q000378:metabolism; D015870:Gene Expression; D035683:MicroRNAs / Q000378:metabolism*; D014981:Xenopus / Q000196:embryology* / Q000235:genetics* / Q000378:metabolism
chemical_list: D035683:MicroRNAs