title: Gas-phase reactivity of aromatic sigma,sigma-biradicals toward dinucleoside phosphates.
abstract: In order to improve the understanding of the interactions of aromatic sigma,sigma-biradicals with DNA, the reactivity of three isomeric sigma,sigma-biradicals toward four dinucleoside phosphates was studied in a mass spectrometer. The dinucleoside phosphates were evaporated into the mass spectrometer by using laser-induced acoustic desorption (LIAD). The results demonstrate that the structure of the sigma,sigma-biradical and the base sequence of the dinucleoside phosphate can have a major influence on these reactions.
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.
authors.forename: Linan
authors.initials: L
authors.lastname: Yang
authors.forename: John J
authors.initials: JJ
authors.lastname: Nash
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Yurkovich
authors.forename: Zhicheng
authors.initials: Z
authors.lastname: Jin
authors.forename: Nelson R
authors.initials: NR
authors.lastname: Vinueza
authors.forename: Hilkka I
authors.initials: HI
authors.lastname: Kenttämaa
mesh_terms: D004247:DNA; D015226:Dinucleoside Phosphates / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D005740:Gases / Q000737:chemistry; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry*; D007834:Lasers; D013058:Mass Spectrometry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D015226:Dinucleoside Phosphates; D005609:Free Radicals; D005740:Gases; D007546:Isoquinolines; D004247:DNA