Specific entities affecting the craniocervical region: Down's syndrome.
BACKGROUND
The ligamentous laxities and bony abnormalities associated with Down's syndrome, os odontoideum, achondroplasia, osteogenesis imperfecta, and basilar invagination have been discussed with the imaging of the craniocervical junction. These are significant and require suspicion when dealing with children with the previously mentioned entities.


CONCLUSIONS
Previous adverse surgical results in managing these patients reflect the lack of understanding of the underlying pathology and the appropriate surgical treatment.
Menezes
Arnold H
AH
Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, IA 52242, USA. arnold-menezes@uiowa.edu
D001268:Atlanto-Axial Joint / Q000002:abnormalities / Q000601:surgery*; D001269:Atlanto-Occipital Joint / Q000002:abnormalities / Q000601:surgery*; D002648:Child; D003952:Diagnostic Imaging / Q000379:methods; D004314:Down Syndrome / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007593:Joint Instability / Q000473:pathology / Q000517:prevention & control / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods