Considerations on temperature, longevity and aging.
A modest reduction in body temperature prolongs longevity and may retard aging in both poikilotherm and homeotherm animals. Some of the possible mechanisms mediating these effects are considered here with respect to major aging models and theories.
Conti
B
B
Molecular and Integrative Neurosciences Department, The Harold Dorris Neurological Research Institute, The Scripps Research Institute, La Jolla, CA 92037, USA. bconti@scripps.edu
D000375:Aging; D000818:Animals; D001831:Body Temperature; D031204:Caloric Restriction; D004734:Energy Metabolism; D006706:Homeostasis; D006801:Humans; D008136:Longevity; D013816:Thermodynamics