C-reactive protein: the harbinger of cardiovascular diseases.
Coronary heart disease remains the major cause of mortality and morbidity in the United States and other western countries despite major advances in its treatment. During the last decades, many markers of coronary artery disease have been found which help predict future risk of cardiovascular events. High-sensitivity C-reactive protein has been studied extensively and was seen to be associated with a higher risk of cardiovascular events in patients with acute coronary syndromes and/or peripheral artery disease. Discussed in this review is the latest literature about this marker and its association with cardiovascular disease, as well as the latest therapeutic options available.
Abi-Saleh
Bernard
B
Department of Medicine, University of South Alabama, Mobile, AL, USA. babisaleh@usouthal.edu
Iskandar
Said B
SB
Elgharib
Nader
N
Cohen
Michael V
MV
D000818:Animals; D015415:Biomarkers / Q000097:blood*; D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology; D042783:Endothelial Cells / Q000502:physiology; D004730:Endothelium, Vascular / Q000166:cytology; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis; D016027:Heart Transplantation; D006349:Heart Valve Diseases / Q000097:blood; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D009569:Nitric Oxide / Q000096:biosynthesis; D011237:Predictive Value of Tests; D011379:Prognosis
D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D009569:Nitric Oxide; D002097:C-Reactive Protein