Thyroid function in children with chronic renal failure.
This study was undertaken to test the thyroid function in non-dialyzed children with chronic renal failure (CRF). Sixteen children with CRF and 12 healthy children who served as controls were studied for their thyroid function status. We found a significant increase in the serum thyroid stimulating hormone (TSH) level and a significant decrease in serum Triiodo thyronine (T3) levels in children with CRF as compared to the healthy children (p 0.2). There was a weak negative correlation between hemoglobin concentration and serum TSH (r = - 45) as well as between blood urea nitrogen and serum T3 (r= -0.30) in children with CRF. These results suggest that children with CRF commonly have a state of biochemical hypothyroidism although they are clinically euthyroid. Early renal transplantation is indicated to correct such metabolic defects.
El-Hana
N A
NA
Jeddah Kidney Center, King Fahad Hospital, Jeddah, Saudi Arabia.
El Shaikh
S
S
Shaheen
F A
FA