[Changes of platelet aggregation in cancer patients].
Aggregation function of platelets was investigated in 119 patients with breast cancer, 17--gastric cancer and 11--cancer of large bowel. Levels of spontaneous and induced aggregation were abnormally high thus contributing to thrombophilic potential. Also, they were a factor of tumor progression and metastatic spread. Risk of thrombotic complication can be reduced and survival improved by administration of antiaggregants.
Shilova
A N
AN
Kotovshchikova
E F
EF
Lazarev
A F
AF
Barkagan
Z S
ZS
Buevich
E I
EI
D001943:Breast Neoplasms / Q000097:blood; D003110:Colonic Neoplasms / Q000097:blood; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D010974:Platelet Aggregation; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D010976:Platelet Count; D013274:Stomach Neoplasms / Q000097:blood; D019851:Thrombophilia / Q000150:complications / Q000209:etiology*; D013927:Thrombosis / Q000209:etiology
D010975:Platelet Aggregation Inhibitors