Non-Candida albicans Candida mediastinitis of odontogenic origin in a diabetic patient.
Descending mediastinitis occurs as a complication of oropharyngeal or cervical infections and its delayed diagnosis and treatment are associated with high mortality. A rare case of an odontogenic infection in a diabetic patient, complicated by Candida parapsilosis and Candida krusei parapharyngeal space infection, descending mediastinitis and aspiration pneumonia is described. Isolate identification was based on colonial and microscopic morphological characteristics and carbohydrate assimilation test results. The patient was successfully treated with surgical drainage and debridement, broad spectrum antibacterials and liposomal amphotericin B followed by prolonged oral voriconazole therapy.
Kofteridis
Diamantis P
DP
Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece. kofterid@med.uoc.gr
Mantadakis
Elpis
E
Karatzanis
Alexander D
AD
Bourolias
Constantinos A
CA
Papazoglou
Georgios
G
Velegrakis
George A
GA
Samonis
George
G
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002180:Candidiasis, Oral / Q000188:drug therapy / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000382:microbiology; D005260:Female; D006801:Humans; D008480:Mediastinitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D009894:Opportunistic Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D011743:Pyrimidines / Q000627:therapeutic use; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D065819:Voriconazole