Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae carbapenemase beta-lactamases associated with long-term care facilities.
Nine carbapenem-resistant Escherichia coli isolates harboring Klebsiella pneumoniae carbapenemase (KPC)-2 or KPC-3 enzymes were identified in patients residing in 7 distinct long-term care facilities. Cefotaxime-hydrolyzing (CTX-M)-type beta-lactamases were also documented in 3 isolates. The identification of these enzymes in patients staying in long-term care facilities should be of great concern to all components of health care systems.
Urban
Carl
C
Infectious Disease Section, New York Hospital Queens, Flushing, New York 11355, USA. cmurban@nyp.org
Bradford
Patricia A
PA
Tuckman
Margareta
M
Segal-Maurer
Sorana
S
Wehbeh
Wehbeh
W
Grenner
Louise
L
Colon-Urban
Rita
R
Mariano
Noriel
N
Rahal
James J
JJ
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015780:Carbapenems / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000235:genetics*; D008134:Long-Term Care; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases; C063912:carbapenemase