title: [Advances in the study of genetic engineering vaccine delivered by probiotics].
abstract: Probiotics are defined as viable microorganisms that exhibit a beneficial effect on the health of the host when they are ingested. They have many beneficial effects for health, and are commonly recognized as safe. With the development of the protein expression technique for probiotics, the study of probiotics to be used as protein, antigen and antibody delivery vehicles becomes a new highlight. This paper used Lactobacillus as the delegate of probiotics, summarized the effect principle, relevant technique and advances of genetic engineering vaccine delivered by probiotics.
authors.affiliation: Department of Medical Technology, West China School of Public Health, Sichuan University, Chengdu 610041, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Wang
authors.forename: Chaowu
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000096:biosynthesis; D005818:Genetic Engineering / Q000379:methods; D005822:Genetic Vectors; D006801:Humans; D007778:Lactobacillus / Q000235:genetics* / Q000276:immunology; D019936:Probiotics / Q000494:pharmacology*; D014614:Vaccines, Synthetic / Q000096:biosynthesis*; D014765:Viral Vaccines / Q000096:biosynthesis
chemical_list: D001428:Bacterial Vaccines; D014614:Vaccines, Synthetic; D014765:Viral Vaccines