Discoid lupus erythematosus in children--a retrospective study of 34 patients.
Discoid lupus erythematosus is much less frequent and studied in children. We undertook a retrospective study of 34 children less than 16 years of age with this disease, seen over a period of 9 years. A female predominance of 2:1 was found. An association between discoid lupus erythematosus and systemic lupus erythematosus was observed in 23.5% of patients, a higher proportion compared to adult discoid lupus erythematosus. Disseminated lesions were much more frequent in patients with criteria for systemic lupus erythematosus (87.5% vs 34%), suggesting that it could be associated with a worse prognosis. Histologic findings were similar to those observed in adult discoid lupus erythematosus.
Sampaio
Maria Carolina de Abreu
MC
Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil. mcasampaio@yahoo.com
de Oliveira
Zilda Najjar Prado
ZN
Machado
Maria Cecília da Matta Rivitti
MC
dos Reis
Vítor Manoel Silva
VM
Vilela
Maria Apparecida Constantino
MA
D000293:Adolescent; D017677:Age Distribution; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D008297:Male; D008487:Medical History Taking; D012189:Retrospective Studies; D017678:Sex Distribution; D012867:Skin / Q000473:pathology