title: Physicochemical characterization of two deproteinized bovine xenografts.
abstract: Calcium phosphate salts, or more specifically hydroxyapatite, are products of great interest in the fields of medical and dental science due to their biocompatibility and osteoconduction property. Deproteinized xenografts are primarily constituted of natural apatites, sintered or not. Variations in the industrial process may affect physicochemical properties and, therefore, the biological outcome. The purpose of this work was to characterize the physical and chemical properties of deproteinized xenogenic biomaterials, Bio-Oss (Geistlich Biomaterials, Wolhuser, Switzerland) and Gen-Ox (Baumer S.A., Brazil), widely used as bone grafts. Scanning electron microscopy, infrared region spectroscopy, X-ray diffraction, thermogravimetry and degradation analysis were conducted. The results show that both materials presented porous granules, composed of crystalline hydroxyapatite without apparent presence of other phases. Bio-Oss presented greater dissolution in Tris-HCl than Gen-Ox in the degradation test, possibly due to the low crystallinity and the presence of organic residues. In conclusion, both commercial materials are hydroxyapatite compounds, Bio-Oss being less crystalline than Gen-Ox and, therefore, more prone to degradation.
authors.affiliation: Department of Endodontics, School of Dentistry of Bauru, University of São Paulo, Bauru, Brazil.
authors.forename: Thais
authors.initials: T
authors.lastname: Accorsi-Mendonça
authors.forename: Márcio Baltazar
authors.initials: MB
authors.lastname: Conz
authors.forename: Teresa Cristina
authors.initials: TC
authors.lastname: Barros
authors.forename: Lídia Agata
authors.initials: LA
authors.lastname: de Sena
authors.forename: Glória de Almeida
authors.initials: Gde A
authors.lastname: Soares
authors.forename: José Mauro
authors.initials: JM
authors.lastname: Granjeiro
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones / Q000502:physiology*; D002417:Cattle; D003764:Dental Materials / Q000737:chemistry*; D008422:Materials Testing; D008903:Minerals / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C077540:Bio-Oss; D001672:Biocompatible Materials; D018786:Bone Substitutes; D003764:Dental Materials; D008903:Minerals