title: Smoking and tea consumption delay onset of Parkinson's disease.
abstract: Cigarette smoking, coffee and tea drinking may protect against Parkinson's disease (PD). These factors were assessed, retrospectively, to measure their effect on the age of PD onset. The study population consisted of 278 consecutive PD patients. Smoking > or =10 pack-years delayed age of PD onset by 3.2 years (p<0.05). Consumption of tea more than 3 cups per day delayed age of motor symptoms onset by 7.7 years (p<0.01). Coffee consumption exceeding 3 cups per day advanced the age of PD onset by 4.8 years (p=0.03). Thus, tea consumption and smoking can delay the age of PD onset, while coffee drinking may have the opposite effect.
authors.affiliation: Department of Physiology and Pharmacology, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Boris
authors.initials: B
authors.lastname: Kandinov
authors.forename: Nir
authors.initials: N
authors.lastname: Giladi
authors.forename: Amos D
authors.initials: AD
authors.lastname: Korczyn
mesh_terms: D017668:Age of Onset; D000368:Aged; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D040503:Coffea / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010300:Parkinson Disease / Q000453:epidemiology / Q000503:physiopathology* / Q000517:prevention & control*; D012189:Retrospective Studies; D012907:Smoking; D013662:Tea
chemical_list: D013662:Tea