title: Biotransformation of (+/-)-2-methylcyclohexanone by fungi.
abstract: The biotransformation of 2-methylcyclohexanone (1) using 16 fungal strains and some mushroom cultures was investigated. Fusarium sp. was one of the effective biocatalysts for oxidoreduction of 2-methylcyclohexanone (1). cis-2-Methylcyclohexanol (2a) was isomerized to trans-2-methylcyclohexanol (2b) by Fusarium sp. In addition, the corresponding lactones 3 was obtained by Baeyer-Villiger oxidation using Fusarium sp. AP-2 (46%, 94% ee).
authors.affiliation: Department of Chemistry, Rikkyo (St. Paul's) University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan.
authors.forename: Mai
authors.initials: M
authors.lastname: Kawamoto
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Utsukihara
authors.forename: Chika
authors.initials: C
authors.lastname: Abe
authors.forename: Michiko
authors.initials: M
authors.lastname: Sato
authors.forename: Michihiko
authors.initials: M
authors.lastname: Saito
authors.forename: Masahiro
authors.initials: M
authors.lastname: Koshimura
authors.forename: Nakahide
authors.initials: N
authors.lastname: Kato
authors.forename: C Akira
authors.initials: CA
authors.lastname: Horiuchi
mesh_terms: D001711:Biotransformation; D002384:Catalysis; D003512:Cyclohexanones / Q000737:chemistry / Q000378:metabolism*; D005670:Fusarium / Q000378:metabolism*; D010084:Oxidation-Reduction; D013997:Time Factors
chemical_list: D003512:Cyclohexanones; C532535:2-methylcyclohexanone