title: [Improvement of overall performance for lung nodule detection in chest CT images].
abstract: We have developed an automated computerized schema for the detection of lung nodules in 3D CT images obtained by helical CT. In our previous schema, linear discriminant analysis (LDA) and a rule-based method with 53 image features were employed in order to reduce false positives. However, several false positives have remained. Therefore, in this study, we improved the false-positive reduction technique by using the edge image and radial image analysis. Overall performance for the detection of lung nodules was greatly improved. Sensitivity was higher than that of our previous study. Moreover, we evaluated the overall performance of the new scheme by using 69 cases acquired from four hospitals. The average number of false positives was 5.2 per case at a percent sensitivity of 95.8%. Our new scheme would assist in the detection of early lung cancer.
authors.affiliation: Hiroshima International University, Faculty of Health Sciences, Department of Clinical Radiology.
authors.forename: Megumi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Ikuo
authors.initials: I
authors.lastname: Kawashita
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Okura
authors.forename: Mitoshi
authors.initials: M
authors.lastname: Akiyama
authors.forename: Koichi
authors.initials: K
authors.lastname: Fujikawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kagemoto
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Mitogawa
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Ubagai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ishine
authors.forename: Katsuhide
authors.initials: K
authors.lastname: Ito
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ishida
mesh_terms: D005189:False Positive Reactions; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic / Q000379:methods*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*