Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness.
A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a >/=4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.
Li
Iris W S
IW
Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong.
To
Kelvin K W
KK
Tang
Bone S F
BS
Chan
Kwok-Hung
KH
Hui
Chee-Kin
CK
Cheng
Vincent C C
VC
Yuen
Kwok-Yung
KY
D000328:Adult; D006801:Humans; D007121:Immunocompetence; D007244:Infectious Mononucleosis / Q000503:physiopathology / Q000821:virology; D008297:Male; D029121:Metapneumovirus / Q000472:pathogenicity*; D018184:Paramyxoviridae Infections / Q000503:physiopathology / Q000821:virology