Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide.
The synthesis of a family of O-silylcarbamates from the corresponding silylamines has been achieved simply by heating the silylamine in supercritical carbon dioxide (scCO2), and these O-silylcarbamates have been shown to be effective precursors for the synthesis of a range of symmetrical and unsymmetrical ureas.
Fuchter
Matthew J
MJ
CSIRO Molecular and Health Technologies, Bag 10, Clayton South, Vic. 3169, Australia.
Smith
Catherine J
CJ
Tsang
Melanie W S
MW
Boyer
Alistair
A
Saubern
Simon
S
Ryan
John H
JH
Holmes
Andrew B
AB
D000588:Amines / Q000737:chemistry; D002219:Carbamates / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D015394:Molecular Structure; D011312:Pressure; D013237:Stereoisomerism; D014297:Trimethylsilyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
D000588:Amines; D002219:Carbamates; D014297:Trimethylsilyl Compounds; D002245:Carbon Dioxide; D014508:Urea