title: Moderate weight loss in obese women with urinary incontinence: a prospective longitudinal study.
abstract: This study assessed the effect of moderate weight loss in obese women with urodynamically proven urinary incontinence using the International Consultation on Incontinence recommended outcome measures. Sixty-four incontinent women were offered a weight reduction programme with a target loss of 5-10%. This included a low-calorie diet and exercise. An anti-obesity drug (Orlistat) was offered to those who failed to achieve their target. Forty-two (65%) achieved the target weight loss and had significant reduction in body mass index and girth. Weight loss was associated with significant reduction in pad test loss (median difference, 19 g; 95% confidence interval, 13-28 g; p < 0.001). There was also a clinical and statistically significant improvement in quality of life measures. These results suggest that weight reduction of 5% of initial body weight can improve urinary incontinence severity and its effects on quality of life in obese women.
authors.affiliation: Urogynaecology Unit, Derriford Hospital, Plymouth, Devon, UK. Wauwad@aol.com
authors.forename: Wael
authors.initials: W
authors.lastname: Auwad
authors.forename: Pippin
authors.initials: P
authors.lastname: Steggles
authors.forename: Luigi
authors.initials: L
authors.lastname: Bombieri
authors.forename: Malcolm
authors.initials: M
authors.lastname: Waterfield
authors.forename: Terrance
authors.initials: T
authors.lastname: Wilkin
authors.forename: Robert
authors.initials: R
authors.lastname: Freeman
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology* / Q000628:therapy*; D011446:Prospective Studies; D011788:Quality of Life; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D001743:Urinary Bladder / Q000503:physiopathology; D014549:Urinary Incontinence / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D014563:Urodynamics; D015431:Weight Loss / Q000502:physiology*