title: Percutaneous aortic valve replacement.
abstract: Aortic valve replacement can produce dramatic benefit in the setting of aortic stenosis. The potential for morbidity and mortality associated with thoracotomy, cardiopulmonary bypass, and aortotomy has fostered a search for alternatives. Early experience with transcatheter endovascular aortic valve implantation demonstrated feasibility and durability, but the procedure was difficult to reproduce. However, equipment, techniques, and experience have evolved rapidly. Balloon-expandable and self-expanding prostheses and percutaneous femoral artery and open left ventricular apical access have found favor, each with potential advantages and disadvantages. Procedural success rates and clinical outcomes continue to improve. Current studies suggest that morbidity and mortality are competitive in comparison to conventional surgery in selected high-risk patients.
authors.affiliation: St. Paul's Hospital, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada. webb@providencehealth.bc.ca
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
mesh_terms: D001024:Aortic Valve Stenosis / Q000473:pathology / Q000601:surgery*; D006328:Cardiac Catheterization; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods