Misdiagnosis of serotonin syndrome as fibromyalgia and the role of physical therapists.
OBJECTIVE
With increased use of serotonergic medications, a condition triggered by serotonin excess within the brain and spinal cord has emerged and may be gaining prevalence. The purposes of this case report are to describe how to identify serotonin syndrome in a patient who is taking citalopram (a selective serotonin reuptake inhibitor) on the basis of signs and symptoms and to promote the ability of physical therapists to recognize such signs and symptoms.


METHODS
The patient was a 42-year-old woman referred for physical therapy with a diagnosis of fibromyalgia. The physical therapist recognized that the patient's symptoms did not resemble those of fibromyalgia and recommended referral to a neurologist for further diagnostic testing.


RESULTS
The patient was referred to a neurologist, who diagnosed serotonin syndrome related to the use of citalopram. The patient was weaned off citalopram and made a successful recovery, with scores on the Oswestry Disability Index decreasing from 70% to 28% at discharge from the physical therapy treatment and to 0% at the 6-month follow-up. The patient has since returned to her prior activity level, which includes skiing, motorcycle riding, and working at her consulting firm.


CONCLUSIONS
This case report demonstrates how careful evaluation by the physical therapist indicated that signs and symptoms were not consistent with fibromyalgia, and further medical evaluation revealed the actual diagnosis of serotonin syndrome.
Alnwick
Gregory M
GM
Genesis Rehabilitation Services, Gorham Outpatient Clinic, 4 Woodbound Rd, Gorham, NH 03581, USA. galnwick@ne.rr.com
D000328:Adult; D015283:Citalopram / Q000009:adverse effects; D003951:Diagnostic Errors; D005260:Female; D005356:Fibromyalgia / Q000175:diagnosis* / Q000534:rehabilitation; D006801:Humans; D026761:Physical Therapy Specialty; D010819:Physician's Role; D020230:Serotonin Syndrome / Q000175:diagnosis* / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects
D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors