Urinary tract infections in children.
Urinary tract infections can be a significant source of morbidity in the pediatric population. The mainstay of evaluating urinary tract infections in children has been physical examination, urinalysis and culture, and renal and bladder sonography and contrast cystography. However, novel clinical paradigms now consider the importance of various risk factors, such as bacterial virulence and antibiotic-resistance patterns, elimination disorders, and the role of innate immunity and inflammation in determining the likelihood of renal cortical scarring.
Sedberry-Ross
Sherry
S
Department of Pediatric Urology, Children's National Medical Center, George Washington University School of Medicine, 111 Michigan Avenue, NW, Washington, DC 20010, USA. ssross@cnmc.org
Pohl
Hans G
HG
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000472:pathogenicity; D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D002648:Child; D002921:Cicatrix / Q000209:etiology* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D007113:Immunity, Innate; D007249:Inflammation / Q000382:microbiology; D007672:Kidney Cortex; D007674:Kidney Diseases / Q000209:etiology* / Q000382:microbiology; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D014718:Vesico-Ureteral Reflux / Q000150:complications; D014774:Virulence
D000900:Anti-Bacterial Agents