Enantioselective synthesis of cyclic sulfamidates via Pd-catalyzed hydrogenation.
Using Pd(CF3CO2) 2/(S,S)-f-binaphane as the catalyst, an efficient enantioselective synthesis of cyclic sulfamidates was developed via asymmetric hydrogenation of the corresponding cyclic imines in 2,2,2-trifluoroethanol at room temperature with high enantioselectivities (up to 99% ee).
Wang
You-Qing
YQ
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
Yu
Chang-Bin
CB
Wang
Da-Wei
DW
Wang
Xiao-Bing
XB
Zhou
Yong-Gui
YG
D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
D009942:Organometallic Compounds; D013449:Sulfonamides; D010165:Palladium