Fatal Rickettsia conorii subsp. israelensis infection, Israel.
Underdiagnosis of fatal spotted fever may be attributed to nonspecific clinical features and insensitive acute-phase serologic studies. We describe the importance of molecular and immunohistochemical methods in establishing the postmortem diagnosis of locally acquired Israeli spotted fever due to Rickettsia conorii subsp. israelensis in a traveler returning to Israel from India.
Weinberger
Miriam
M
Infectious Diseases Unit, Assaf Harofeh Medical Center, Zerifin 70300, Israel. miriw@netvision.net.il
Keysary
Avi
A
Sandbank
Judith
J
Zaidenstein
Ronit
R
Itzhaki
Avi
A
Strenger
Carmela
C
Leitner
Moshe
M
Paddock
Christopher D
CD
Eremeeva
Marina E
ME
D001344:Autopsy; D001907:Boutonneuse Fever / Q000175:diagnosis* / Q000188:drug therapy; D017809:Fatal Outcome; D006801:Humans; D007194:India; D007557:Israel / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D020114:Rickettsia conorii / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D014195:Travel