title: Sonography-guided OK-432 sclerotherapy for benign thyroid cysts.
abstract: CONCLUSIONS
  Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients.
  
  
  OBJECTIVE
  To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts.
  
  
  METHODS
  The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05).
  
  
  RESULTS
  Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3%) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Korea.
authors.forename: Seung Hyun
authors.initials: SH
authors.lastname: Cho
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Lee
authors.forename: Kwang Yoon
authors.initials: KY
authors.lastname: Jung
authors.forename: Jeong Su
authors.initials: JS
authors.lastname: Woo
authors.forename: Seung Kuk
authors.initials: SK
authors.lastname: Back
authors.forename: Ji Ho
authors.initials: JH
authors.lastname: Choi
authors.forename: Jun
authors.initials: J
authors.lastname: Choi
authors.forename: Soon-Young
authors.initials: SY
authors.lastname: Kwon
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D003560:Cysts / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000008:administration & dosage*; D012008:Recurrence; D019233:Retreatment; D015911:Sclerotherapy / Q000379:methods*; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000628:therapy*; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil