title: Role of non-operative management of spleen injury in patients with hemophilia: report of two patients with review of literature.
abstract: The non-operative management (NOM) of hemodynamically stable patients with splenic trauma is currently well accepted, yet non-operative therapy has rarely been attempted in coagulopathic patients. Two cases of successful NOM of splenic trauma in patients with hemophilia are presented with a review of the English medical literature.
authors.affiliation: Trauma Services, The Toledo Hospital & Toledo Children's Hospital, Toledo, Ohio 43606-3895, USA.
authors.forename: Om P
authors.initials: OP
authors.lastname: Sharma
authors.forename: Michael F
authors.initials: MF
authors.lastname: Oswanski
authors.forename: Nabil M
authors.initials: NM
authors.lastname: Issa
authors.forename: Dagmar T
authors.initials: DT
authors.lastname: Stein
mesh_terms: D000063:Accidents, Traffic; D000293:Adolescent; D000328:Adult; D001642:Bicycling / Q000293:injuries; D001779:Blood Coagulation Factors / Q000008:administration & dosage; D001803:Blood Transfusion; D006467:Hemophilia A / Q000188:drug therapy; D002836:Hemophilia B / Q000188:drug therapy; D006801:Humans; D008297:Male; D013154:Spleen / Q000293:injuries*; D016896:Treatment Outcome; D014949:Wounds, Nonpenetrating / Q000628:therapy*
chemical_list: D001779:Blood Coagulation Factors