title: [Pathological change in hydatid cysts of Echinococcus granulosus treated with high intensity focused ultrasound].
abstract: OBJECTIVE
  To investigate the pathological change in Echinococcus granulosus hydatid cysts treated with high intensity focus ultrasound (HIFU).
  
  
  METHODS
  Thirty cysts with thinner wall and proper elasticity, taken from livers of infected sheep, were randomly divided into three groups. By cyclical multilayer radiation around the cyst wall, two experiment groups were treated with HIFU under 150 W and 250 W sound power respectively. The control group was treated by ordinary ultrasound for 2 min.
  
  
  RESULTS
  The inner cyst wall of hydatid treated with HIFU became curved, thicker, stiffer, white and less transparent. The germinal layer was detached mostly from the laminated layers of hydatid in the experiment groups. Images from the transmission electron microscopy showed that in the experiment groups fabric texture of hydatid changed significantly and germinal cells were broken.
  
  
  CONCLUSIONS
  HIFU in a model of cyclical multilayer radiation causes pathological damage of the E. granulosus hydatid.
authors.affiliation: Department of Pathobiology, Chongqing Medical University, Chongqing 400016, China.
authors.forename: Jun-An
authors.initials: JA
authors.lastname: Wang
authors.forename: Xiao-Yi
authors.initials: XY
authors.lastname: Zou
authors.forename: Bin
authors.initials: B
authors.lastname: Ye
authors.forename: Cheng-Wu
authors.initials: CW
authors.lastname: Zhang
authors.forename: Fa-Sheng
authors.initials: FS
authors.lastname: Zhao
mesh_terms: D000818:Animals; D004443:Echinococcosis / Q000473:pathology / Q000628:therapy* / Q000662:veterinary; D048209:Echinococcus granulosus / Q000302:isolation & purification*; D008107:Liver Diseases / Q000469:parasitology / Q000473:pathology / Q000628:therapy*; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology / Q000628:therapy; D016896:Treatment Outcome; D014464:Ultrasonic Therapy / Q000379:methods*