Suppressive effects of topical mometasone furoate and tacrolimus on skin prick testing in children.
Skin prick tests were performed in 12 children with atopic eczema before and after 2 weeks of treatment with topical mometasone furoate and tacrolimus. Both treatments significantly suppressed the allergen wheal size. Mometasone furoate reduced the histamine wheal size as well. Skin prick testing in children treated with topical glucocorticoids or tacrolimus is associated with a risk of false-negative test results.
Gradman
Josefine
J
Children's Clinic Randers, Randers, Denmark. j.gradman@dadlnet.dk
Wolthers
Ole D
OD
D000287:Administration, Topical; D000485:Allergens; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000188:drug therapy*; D004311:Double-Blind Method; D005188:False Negative Reactions; D005260:Female; D006632:Histamine; D006801:Humans; D008297:Male; D000068656:Mometasone Furoate; D011244:Pregnadienediols / Q000008:administration & dosage*; D012882:Skin Tests; D016559:Tacrolimus / Q000008:administration & dosage*
D000485:Allergens; D011244:Pregnadienediols; D000068656:Mometasone Furoate; D006632:Histamine; D016559:Tacrolimus