title: Discoid lupus erythematosus in children--a retrospective study of 34 patients.
abstract: Discoid lupus erythematosus is much less frequent and studied in children. We undertook a retrospective study of 34 children less than 16 years of age with this disease, seen over a period of 9 years. A female predominance of 2:1 was found. An association between discoid lupus erythematosus and systemic lupus erythematosus was observed in 23.5% of patients, a higher proportion compared to adult discoid lupus erythematosus. Disseminated lesions were much more frequent in patients with criteria for systemic lupus erythematosus (87.5% vs 34%), suggesting that it could be associated with a worse prognosis. Histologic findings were similar to those observed in adult discoid lupus erythematosus.
authors.affiliation: Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil. mcasampaio@yahoo.com
authors.forename: Maria Carolina de Abreu
authors.initials: MC
authors.lastname: Sampaio
authors.forename: Zilda Najjar Prado
authors.initials: ZN
authors.lastname: de Oliveira
authors.forename: Maria Cecília da Matta Rivitti
authors.initials: MC
authors.lastname: Machado
authors.forename: Vítor Manoel Silva
authors.initials: VM
authors.lastname: dos Reis
authors.forename: Maria Apparecida Constantino
authors.initials: MA
authors.lastname: Vilela
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D008297:Male; D008487:Medical History Taking; D012189:Retrospective Studies; D017678:Sex Distribution; D012867:Skin / Q000473:pathology