title: [Study on molluscicidal effect of chlorosalicylicamide].
abstract: OBJECTIVE
  To observe the molluscicidal effect of chlorosalicylicamide on Oncomelania hupensis and toxicity on fishes.
  
  
  METHODS
  Different concentrations of chlorosalicylicamide were prepared, and immersion and spraying methods were used to test its molluscicidal effect and toxicity to fishes. Niclosamide ethanolamine salt was used as control.
  
  
  RESULTS
  Under water temperature of 28 C with the dose of chlorosalicylicamide at 0.25 mg/L and 0.4 mg/L, the mortality rate of snails by immersion was 97.8% and 100% respectively after 48 h, and the LC50 was 0.0674 mg/L. While for niclosamide at the same doses, the mortality rate of snails was 22.2% and 66.7% respectively, and the LC50 was 0.397 6 mg/L. With the concentration of 0.4 mg/L for 72 h, the fish death rate in chlorosalicylicamide and niclosamide was 50.0% and 100% respectively.
  
  
  CONCLUSIONS
  Chlorosalicylicamide shows a molluscicidal effect on Oncomelania snails and a lower toxicity to fishes than that of niclosamide.
authors.affiliation: Department of Chemistry and Chemical Industry, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Jin
authors.forename: Jin-kui
authors.initials: JK
authors.lastname: Du
authors.forename: Yi
authors.initials: Y
authors.lastname: Yuan
authors.forename: Feng-hua
authors.initials: FH
authors.lastname: Wei
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Gui-ling
authors.initials: GL
authors.lastname: Li
authors.forename: Xing-jian
authors.initials: XJ
authors.lastname: Xu
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D008975:Molluscacides / Q000494:pharmacology*; D009534:Niclosamide / Q000494:pharmacology*; D012908:Snails / Q000187:drug effects*
chemical_list: D008975:Molluscacides; D009534:Niclosamide