Looking for disease being a model of human aging.
This paper is a part of an introduction to authors' study on systemic laminopathies and their role in human aging. Of special interest is progeria--a type of systemic laminopathy associated usually with mutation 1824 C > T and presenting phenotype of preliminary aging. The authors analyse the differences between the progeria and other syndrome of preliminary aging--Werner's syndrome.
Hausmanowa-Petrusewicz
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I
Neuromuscular Unit, Institute of Experimental and Clinical Medicine, Polish Academy of Sciences, Warsaw, Poland. neurmyol@cmdik.pan.pl
Madej-Pilarczyk
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A
D000375:Aging; D006801:Humans; D008954:Models, Biological; D011371:Progeria / Q000503:physiopathology*; D011379:Prognosis; D012307:Risk Factors; D014898:Werner Syndrome / Q000503:physiopathology