Optical coherence tomography predictive factors for macular hole surgery outcome.
OBJECTIVE
To evaluate the use of preoperative optical coherence tomography (OCT) findings as predictive factors for macular hole (MH) surgery outcomes.


METHODS
46 eyes from 46 patients with a diagnosis of MH were included in this study. In all cases, a pars plana 25-gauge vitrectomy with peeling of the internal limiting membrane was performed. Before and after surgery, a complete clinical examination and a detailed macular analysis, which included the MH minimum and base diameter, the MH height, the Macular Hole Index (MHI), Diameter Hole Index (DHI) and Tractional Hole Index (THI), were performed. Predictive factors for visual prognosis after surgery were obtained by receiver operating characteristic curve analysis.


RESULTS
Minimum and base diameter as well as THI and MHI correlated significantly (p<0.01, p = 0.01, p = 0.04, p = 0.03, respectively) with postoperative best spectacle corrected visual acuity at 3 months, but DHI and MH height did not. Cut-off values of 311 microm and 1.41 were obtained for the minimum diameter and THI, respectively, from receiver operating characteristic curve analysis, providing an acceptable sensitivity and specificity.


CONCLUSIONS
An MH minimum diameter of <311 microm or a THI >1.41 are predictive factors for a good visual prognosis after MH surgery.
Ruiz-Moreno
J M
JM
Albacete Medical School, University of Castilla La Mancha, Albacete, Spain.
Staicu
C
C
Piñero
D P
DP
Montero
J
J
Lugo
F
F
Amat
P
P
D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012167:Retinal Perforations / Q000503:physiopathology / Q000601:surgery*; D041623:Tomography, Optical Coherence / Q000379:methods / Q000592:standards*; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy