title: Use of the TIMI frame count in the assessment of coronary artery blood flow and microvascular function over the past 15 years.
abstract: Since its introduction, the TIMI frame count method has contributed to the understanding of the pathophysiology of coronary artery disease. In this article, the evolution of the TFC method and its applicability in the assessment of various therapeutic modalities are described.
authors.affiliation: Cardiovascular Divisions, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
authors.forename: Vijayalakshmi
authors.initials: V
authors.lastname: Kunadian
authors.forename: Caitlin
authors.initials: C
authors.lastname: Harrigan
authors.forename: Cafer
authors.initials: C
authors.lastname: Zorkun
authors.forename: Alexandra M
authors.initials: AM
authors.lastname: Palmer
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Ogando
authors.forename: Leah H
authors.initials: LH
authors.lastname: Biller
authors.forename: Erin E
authors.initials: EE
authors.lastname: Lord
authors.forename: Scott P
authors.initials: SP
authors.lastname: Williams
authors.forename: Michelle E
authors.initials: ME
authors.lastname: Lew
authors.forename: Lauren N
authors.initials: LN
authors.lastname: Ciaglo
authors.forename: Jacqueline L
authors.initials: JL
authors.lastname: Buros
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Marble
authors.forename: William J
authors.initials: WJ
authors.lastname: Gibson
authors.forename: C Michael
authors.initials: CM
authors.lastname: Gibson
mesh_terms: D017023:Coronary Angiography / Q000266:history / Q000379:methods*; D003324:Coronary Artery Disease / Q000175:diagnosis*; D003326:Coronary Circulation; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008833:Microcirculation