title: Overview of model systems for the analysis of human disease.
abstract: The development of animal models of human disease has been crucial in elucidating normal organ biology and pathogenic mechanisms leading to disease states, and in the development of new therapeutic strategies to modify disease. This unit provides an overview of various animal models used in the study of human disease and the factors that need to be considered when selecting a suitable animal model appropriate for the disease under investigation.
authors.affiliation: Centenary Institute, Sydney, Australia.
authors.forename: Joanne
authors.initials: J
authors.lastname: Lind
authors.forename: Christopher
authors.initials: C
authors.lastname: Semsarian
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D018390:Gene Targeting; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic