title: Non-invasive diagnosis of coronary artery disease using cardiogoniometry performed at rest.
abstract: BACKGROUND
  Cardiogoniometry is a non-invasive technique for quantitative three-dimensional vectorial analysis of myocardial depolarization and repolarization. We describe a method of surface electrophysiological cardiac assessment using cardiogoniometry performed at rest to detect variables helpful in identifying coronary artery disease.
  
  
  METHODS
  Cardiogoniometry was performed in 793 patients prior to diagnostic coronary angiography. Using 13 variables in men and 10 in women, values from 461 patients were retrospectively analyzed to obtain a diagnostic score that would identify patients having coronary artery disease. This score was then prospectively validated on 332 patients.
  
  
  RESULTS
  Cardiogoniometry showed a prospective diagnostic sensitivity of 64%, and a specificity of 82%. ECG diagnostic sensitivity was significantly lower, with 53% and a similar specificity of 75%.
  
  
  CONCLUSIONS
  Cardiogoniometry is a new, noninvasive, quantitative electrodiagnostic technique which is helpful in identifying patients with coronary artery disease. It can easily be performed at rest and delivers an accurate, automated diagnostic score.
authors.affiliation: Department of Cardiology, University Hospital, Inselspital, Bern, Switzerland. michael.schupbach@wanadoo.fr
authors.forename: W M Michael
authors.initials: WM
authors.lastname: Schüpbach
authors.forename: Bernhard
authors.initials: B
authors.lastname: Emese
authors.forename: Patrick
authors.initials: P
authors.lastname: Loretan
authors.forename: Alain
authors.initials: A
authors.lastname: Mallet
authors.forename: Firat
authors.initials: F
authors.lastname: Duru
authors.forename: Ernst
authors.initials: E
authors.lastname: Sanz
authors.forename: Bernhard
authors.initials: B
authors.lastname: Meier
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014672:Vectorcardiography / Q000379:methods*