title: Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae carbapenemase beta-lactamases associated with long-term care facilities.
abstract: Nine carbapenem-resistant Escherichia coli isolates harboring Klebsiella pneumoniae carbapenemase (KPC)-2 or KPC-3 enzymes were identified in patients residing in 7 distinct long-term care facilities. Cefotaxime-hydrolyzing (CTX-M)-type beta-lactamases were also documented in 3 isolates. The identification of these enzymes in patients staying in long-term care facilities should be of great concern to all components of health care systems.
authors.affiliation: Infectious Disease Section, New York Hospital Queens, Flushing, New York 11355, USA. cmurban@nyp.org
authors.forename: Carl
authors.initials: C
authors.lastname: Urban
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Bradford
authors.forename: Margareta
authors.initials: M
authors.lastname: Tuckman
authors.forename: Sorana
authors.initials: S
authors.lastname: Segal-Maurer
authors.forename: Wehbeh
authors.initials: W
authors.lastname: Wehbeh
authors.forename: Louise
authors.initials: L
authors.lastname: Grenner
authors.forename: Rita
authors.initials: R
authors.lastname: Colon-Urban
authors.forename: Noriel
authors.initials: N
authors.lastname: Mariano
authors.forename: James J
authors.initials: JJ
authors.lastname: Rahal
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015780:Carbapenems / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000235:genetics*; D008134:Long-Term Care; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases; C063912:carbapenemase