Bone response to a Ca- and P-enriched titanium surface obtained by anodization.
This study evaluated bone response to a Ca- and P- enriched titanium (Ti) surface treated by a multiphase anodic spark deposition coating (BSP-AK). Two mongrel dogs received bilateral implantation of 3 Ti cylinders (4.1 x 12 mm) in the humerus, being either BSP-AK treated or untreated (machined - control). At 8 weeks postimplantation, bone fragments containing the implants were harvested and processed for histologic and histomorphometric analyses. Bone formation was observed in cortical area and towards the medullary canal associated to approximately 1/3 of implant extension. In most cases, in the medullary area, collagen fiber bundles were detected adjacent and oriented parallel to Ti surfaces. Such connective tissue formation exhibited focal areas of mineralized matrix lined by active osteoblasts. The mean percentages of bone-to-implant contact were 2.3 (0.0-7.2 range) for BSP-AK and 0.4 (0.0-1.3 range) for control. Although the Mann-Whitney test did not detect statistically significant differences between groups, these results indicate a trend of BSP-AK treated surfaces to support contact osteogenesis in an experimental model that produces low bone-to-implant contact values.
Franco
Rosemeire de Lordo
Rde L
Cell Culture Laboratory, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Chiesa
Roberto
R
de Oliveira
Paulo Tambasco
PT
Beloti
Marcio Mateus
MM
Rosa
Adalberto Luiz
AL
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D016723:Bone Remodeling / Q000502:physiology; D002118:Calcium / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003094:Collagen; D003238:Connective Tissue / Q000473:pathology; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D017267:Dental Prosthesis Design; D004285:Dogs; D004577:Electron Probe Microanalysis; D004595:Electroplating / Q000379:methods*; D006811:Humerus / Q000473:pathology* / Q000601:surgery; D008855:Microscopy, Electron, Scanning; D023421:Models, Animal; D016348:Osseointegration / Q000502:physiology; D010006:Osteoblasts / Q000473:pathology; D010010:Osteoclasts / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology; D010100:Oxygen / Q000032:analysis; D010758:Phosphorus / Q000737:chemistry*; D016062:Porosity; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D010758:Phosphorus; D003094:Collagen; D014025:Titanium; D010100:Oxygen; D002118:Calcium