[Comparison of activities of various species of Rhizoma Cimicifugae and their honey processed products].
OBJECTIVE
To compare the analgesic and sedative effects of various species of Rhizoma Cimicifugae and their processed products with honey.


METHODS
The three kinds of analgesic experiments of formalin, hot plate and writhing tests, and the number of spontaneous activities and raise forelimbs were adopted in mice.


RESULTS
All samples showed antinociceptive activities in the two phases of formalin, tail immersion and writhing tests and sedative properties in the spontaneous locomotor activity test. The analgesic and sedative effects of processed Rhizoma Cimicifugae were higher than crude drugs.


CONCLUSIONS
The present results demonstrate that the antinociceptive and sedative activity of samples processed with honey are more potent than crude drugs.
Cao
Li
L
Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100094, China.
Sun
Hong
H
Li
Zhan
Z
Pan
Rui-le
RL
D000700:Analgesics; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D031885:Cimicifuga / Q000737:chemistry* / Q000145:classification; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006722:Honey; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009043:Motor Activity / Q000187:drug effects*; D010147:Pain Measurement; D017288:Pain Threshold / Q000187:drug effects*; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
D000700:Analgesics; D004365:Drugs, Chinese Herbal