title: Quantitative genetic studies of antisocial behaviour.
abstract: This paper will broadly review the currently available twin and adoption data on antisocial behaviour (AB). It is argued that quantitative genetic research can make a significant contribution to further the understanding of how AB develops. Genetically informative study designs are particularly useful for investigating several important questions such as whether: the heritability estimates vary as a function of assessment method or gender; the relative importance of genetic and environmental influences varies for different types of AB; the environmental risk factors are truly environmental; and genetic vulnerability influences susceptibility to environmental risk. While the current data are not yet directly translatable for prevention and treatment programmes, quantitative genetic research has concrete translational potential. Quantitative genetic research can supplement neuroscience research in informing about different subtypes of AB, such as AB coupled with callous-unemotional traits. Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates.
authors.affiliation: Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK. e.viding@ucl.ac.uk
authors.forename: Essi
authors.initials: E
authors.lastname: Viding
authors.forename: Henrik
authors.initials: H
authors.lastname: Larsson
authors.forename: Alice P
authors.initials: AP
authors.lastname: Jones
mesh_terms: D000987:Antisocial Personality Disorder / Q000235:genetics*; D036281:Genetic Research; D006801:Humans; D012920:Social Behavior Disorders / Q000235:genetics*; D012931:Social Environment