title: Primary Nocardia farcinica brain abscess with secondary meningitis and ventriculitis in an immunocompetent patient, successfully treated with moxifloxacin.
abstract: We report a rare case of Nocardia farcinica occipital brain abscess in an immunocompetent patient with no underlying risk factors successfully treated with the antibiotic moxifloxacin. The patient underwent craniotomy and abscess drainage. Initial post-operative treatment with co-trimoxazole produced a limited response. Despite the development of skull base meningitis and ventriculitis subsequent addition of moxifloxacin produced an excellent outcome.
authors.affiliation: Department of Clinical Neurosurgery, The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, UK.
authors.forename: J
authors.initials: J
authors.lastname: Kandasamy
authors.forename: H J
authors.initials: HJ
authors.lastname: Iqbal
authors.forename: R P D
authors.initials: RP
authors.lastname: Cooke
authors.forename: P R
authors.initials: PR
authors.lastname: Eldridge
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001372:Aza Compounds / Q000627:therapeutic use*; D001922:Brain Abscess / Q000382:microbiology* / Q000601:surgery; D002552:Cerebral Ventricles / Q000382:microbiology*; D004322:Drainage; D004660:Encephalitis / Q000382:microbiology*; D024841:Fluoroquinolones; D006801:Humans; D007121:Immunocompetence; D008297:Male; D016920:Meningitis, Bacterial / Q000382:microbiology*; D000077266:Moxifloxacin; D019635:Neurosurgical Procedures; D009617:Nocardia Infections / Q000150:complications* / Q000188:drug therapy; D009778:Occipital Lobe / Q000382:microbiology; D011182:Postoperative Care; D011804:Quinolines / Q000627:therapeutic use*; D019291:Skull Base / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D000077266:Moxifloxacin