Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions.
The coupling of activated esters to gramine derivatives is described using ethyl propiolate. A series of substrates have been prepared using these mild conditions to provide a scope and limitations for this methodology.
Jones
David T
DT
Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA University of Colorado Cancer Center, Aurora, CO 80045.
Artman
Gerald D
GD
Williams
Robert M
RM