title: Recent antiviral strategies against human coronavirus-related respiratory illnesses.
abstract: OBJECTIVE
  The main purpose of this review is to summarize the current research (2006-2007) concerning the development of novel anticoronaviral strategies and compounds.
  
  
  RESULTS
  Recent research led to the identification of several novel agents inhibiting coronaviral replication. The most promising compounds include carbohydrate-binding agents, neutralizing antibodies and drugs targeting a coronaviral envelope protein.
  
  
  CONCLUSIONS
  Although initial outbreaks of coronavirus that causes severe acute respiratory syndrome (SARS-CoV) were controlled by public health measures, the development of vaccines and antiviral agents for SARS-CoV is essential for improving control and treatment of future outbreaks. Four years after the SARS-CoV epidemic, several compounds with an anticoronaviral activity have been identified.
authors.affiliation: Microbiology Department, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Golda
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Pyrc
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D018352:Coronavirus Infections / Q000188:drug therapy*; D006801:Humans; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000821:virology*
chemical_list: D000998:Antiviral Agents