Free recall and forgetting of emotionally arousing words in autism spectrum disorder.
Since the earliest descriptions of individuals with autism spectrum disorders (ASDs) abnormalities in affective behaviours have been considered a prominent feature in their clinical manifestations. What remains unclear, however, is whether these altered emotional behaviours are a mere facet of abnormalities in socio-cognitive processes or whether they constitute a primary feature of the condition. A number of studies now indicate that emotional processing atypicalities in ASD extend to domains outside the broader context of social cognition leading us to suggest that the disorder may be characterised by basic abnormalities in how psychophysiological and cognitive emotional responses modulate one another [Gaigg, S. B. & Bowler, D. M. (2007). Differential fear conditioning in Asperger's syndrome: Implications for an amygdala theory of autism. Neuropsychologia, 45, 2125-2134]. In the current study, we show that although individuals with ASD, like typical individuals, exhibit a free recall advantage for emotionally arousing and semantically related neutral as compared to unrelated neutral words, they do not show reduced forgetting rates for arousing stimuli as do typical individuals. These observations provide further support for the view that psychophysiological emotional responses do not modulate cognitive processes normally in ASD and further implicate abnormalities of amygdala connectivity (in particular with the hippocampus) in the neuropathology underlying this disorder.
Gaigg
Sebastian B
SB
City University, London, UK. s.b.gaigg@city.ac.uk
Bowler
Dermot M
DM
D000328:Adult; D000339:Affect / Q000502:physiology*; D000679:Amygdala / Q000503:physiopathology; D000704:Analysis of Variance; D001245:Association Learning / Q000502:physiology; D001321:Autistic Disorder / Q000503:physiopathology* / Q000523:psychology*; D016022:Case-Control Studies; D003214:Conditioning, Classical / Q000502:physiology; D004192:Discrimination, Psychological / Q000502:physiology; D004644:Emotions / Q000502:physiology; D005260:Female; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D007802:Language; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D009483:Neuropsychological Tests; D012153:Retention, Psychology / Q000502:physiology*; D012660:Semantics; D012919:Social Behavior; D014888:Wechsler Scales; D014956:Writing