title: Lithium-induced nephrotic syndrome in a prepubertal boy.
abstract: Lithium carbonate has been recognized to induce several renal side effects, including the nephrotic syndrome. This is a report of an 11-year-old, prepubertal boy with a mood disorder treated with lithium who presented with edema, bilateral pulmonary effusions, proteinuria, and hypoalbuminemia. Renal biopsy revealed pathologic changes consistent with minimal change disease. These symptoms normalized after lithium discontinuation.
authors.affiliation: Navy Medicine Manpower Personnel Training and Education Command, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. carl.petersen@med.navy.mil
authors.forename: Carl E
authors.initials: CE
authors.lastname: Petersen
authors.forename: Sandra
authors.initials: S
authors.lastname: Amaral
authors.forename: Emily
authors.initials: E
authors.lastname: Frosch
mesh_terms: D018692:Antimanic Agents / Q000633:toxicity*; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000175:diagnosis / Q000188:drug therapy; D001706:Biopsy; D002648:Child; D015897:Comorbidity; D004359:Drug Therapy, Combination; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D016651:Lithium Carbonate / Q000633:toxicity*; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis / Q000188:drug therapy*; D009402:Nephrosis, Lipoid / Q000139:chemically induced* / Q000473:pathology; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000473:pathology
chemical_list: D018692:Antimanic Agents; D016651:Lithium Carbonate