title: Influence of optical heterogeneities on reconstruction of spatial phosphorescence lifetime distributions.
abstract: We have previously demonstrated that phosphorescence lifetime imaging (PLI) allows for unbiased determination of absolute oxygen levels in homogeneously absorbing/scattering media. We computationally show that tomographic PLI can perform equally well in heterogeneous environments relying only on surface measurements of phosphorescence.
authors.affiliation: Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Sofia V
authors.initials: SV
authors.lastname: Apreleva
authors.forename: Sergei A
authors.initials: SA
authors.lastname: Vinogradov
mesh_terms: D000465:Algorithms; D007091:Image Processing, Computer-Assisted; D008163:Luminescent Measurements / Q000295:instrumentation / Q000379:methods*; D008962:Models, Theoretical; D055095:Optics and Photonics