The 'core' and 'accessory' regulons of Pseudomonas-specific extracytoplasmic sigma factors.
Pyoverdine is a fluorescent, high-affinity peptide siderophore produced by different Pseudomonas species. The genes for pyoverdine biosynthesis depend on PvdS, an extracytoplasmic sigma factor. In this issue of Molecular Microbiology, Swingle et al. demonstrate that in the plant pathogen Pseudomonas syringae PvdS not only regulates the production of pyoverdine (core regulon), but also controls expression of other genes likely to be involved in the adaptation to the environment (accessory regulon). This accessory regulon is variable, as different sets of genes seem to be recruited according to the Pseudomonas species and its specific ecological niche.
Cornelis
Pierre
P
Microbial Interactions, Department of Molecular and Cellular Interactions, Flanders Institute of Biotechnology (VIB) and Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium. pcornel@vub.ac.be
D000222:Adaptation, Physiological / Q000235:genetics; D003593:Cytoplasm / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D009842:Oligopeptides / Q000096:biosynthesis / Q000235:genetics*; D044224:Pseudomonas syringae / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D018085:Regulon; D012808:Sigma Factor / Q000378:metabolism*
D009842:Oligopeptides; D012808:Sigma Factor; C042453:pyoverdin