Solitary fibrous tumour of the liver with IGF-II-related hypoglycaemia. A case report.
BACKGROUND
We report a rare case of solitary fibrous tumour (SFT) of the liver associated with non-islet cell tumour hypoglycaemia (NICTH), which caused a hypoglycaemic coma due to over-production of big-insulin-like growth factor-II.


CONCLUSIONS
Although generally benign, SFTs are better characterised, lately due to Western blot, but less than 40 cases have been reported where the liver is the target organ. In only two benign cases has hypoglycaemia been a feature.


CONCLUSIONS
We report for the first time a demonstrable relationship between benign liver SFT and NICTH.
Famà
F
F
Department of Human Pathology, University Hospital of Messina, Messina, Italy. famafausto@yahoo.it
Le Bouc
Yves
Y
Barrande
G
G
Villeneuve
A
A
Berry
M G
MG
Pidoto
R R
RR
Saint Marc
O
O
D000368:Aged; D003128:Coma / Q000097:blood / Q000209:etiology*; D003937:Diagnosis, Differential; D006498:Hepatectomy; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism*; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000209:etiology*; D011498:Protein Precursors / Q000097:blood*; D054364:Solitary Fibrous Tumors / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D036542:Tomography, Spiral Computed
D011498:Protein Precursors; C066038:proinsulin-like growth factor II; D007335:Insulin-Like Growth Factor II