title: Quality of life one year after chemoradiotherapy for localized primary gastric diffuse large B-cell lymphoma.
abstract: We assessed the quality of life (QOL) at least one year after sequential chemoradiotherapy for the treatment of localized gastric diffuse large B-cell lymphoma (DLBCL). We used the EORTC Quality of Life Questionnaire for Stomach Cancer (EORTC QLQ-STO22). Among the 45 patients available at the one-year follow-up after radiation therapy, 40 patients completed the EORTC QLQ-STO22 questionnaire. Their median age was 54.5 (range, 20-70 years). Social functioning was most adversely affected among the respondents with a score of 59, whereas other functions and the global scales were preserved above a score of 70 by linearly transformed values. Fatigue, the financial impact and specific emotional problems such as "thinking about their illness" (STO-ANX) and "worry about weight loss or future health" (STO-BI) were persistently bothersome for some patients. Other stomach-related symptoms such as dysphagia, pain, or reflux were negligible at 1 year after treatment. Therefore, this organ-preserving combined approach was effective for the maintenance of the QOL and minimization of stomach abnormalities in patients with gastric lymphoma.
authors.affiliation: Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Won Seog
authors.initials: WS
authors.lastname: Kim
authors.forename: Yeon Hee
authors.initials: YH
authors.lastname: Park
authors.forename: Se-Hoon
authors.initials: SH
authors.lastname: Lee
authors.forename: Baek-Yeol
authors.initials: BY
authors.lastname: Ryoo
authors.forename: Sung Hyun
authors.initials: SH
authors.lastname: Yang
authors.forename: Seung-Sook
authors.initials: SS
authors.lastname: Lee
authors.forename: Mi Sook
authors.initials: MS
authors.lastname: Kim
authors.forename: Kihyun
authors.initials: K
authors.lastname: Kim
authors.forename: Keon Woo
authors.initials: KW
authors.lastname: Park
authors.forename: Do Hyoung
authors.initials: DH
authors.lastname: Im
authors.forename: Jung Hun
authors.initials: JH
authors.lastname: Kang
authors.forename: Jeeyun
authors.initials: J
authors.lastname: Lee
authors.forename: Young H
authors.initials: YH
authors.lastname: Ko
authors.forename: Yong Chan
authors.initials: YC
authors.lastname: Ahn
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Lim
authors.forename: Keunchil
authors.initials: K
authors.lastname: Park
authors.forename: Soo-Mee
authors.initials: SM
authors.lastname: Bang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000523:psychology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011878:Radiotherapy; D013274:Stomach Neoplasms / Q000523:psychology* / Q000628:therapy*; D011795:Surveys and Questionnaires
chemical_list: D000970:Antineoplastic Agents