Sonography-guided OK-432 sclerotherapy for benign thyroid cysts.
CONCLUSIONS
Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients.


OBJECTIVE
To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts.


METHODS
The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05).


RESULTS
Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3%) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.
Cho
Seung Hyun
SH
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Korea.
Lee
Seung Hoon
SH
Jung
Kwang Yoon
KY
Woo
Jeong Su
JS
Back
Seung Kuk
SK
Choi
Ji Ho
JH
Choi
Jun
J
Kwon
Soon-Young
SY
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D003560:Cysts / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000008:administration & dosage*; D012008:Recurrence; D019233:Retreatment; D015911:Sclerotherapy / Q000379:methods*; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000628:therapy*; D016896:Treatment Outcome; D014463:Ultrasonography
D000970:Antineoplastic Agents; D010844:Picibanil