Gene therapy progress and prospects cancer: oncolytic viruses.
The past 2 years have seen several major advances in oncolytic virotherapy. Studies on the interaction between viruses, immune responses and tumor microenvironment have provided important insight, while clinical trials have shown promise. This review summarizes key findings in this field over the past 2 years, and provides directions for future success.
Liu
T-C
TC
Department of Clinical Research, Jennerex Biotherapeutics Inc., San Francisco, CA, USA.
Kirn
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D
D000818:Animals; D002986:Clinical Trials as Topic; D005544:Forecasting; D005818:Genetic Engineering; D015316:Genetic Therapy / Q000379:methods* / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D050130:Oncolytic Virotherapy / Q000379:methods* / Q000639:trends; D050504:Oncolytic Viruses / Q000235:genetics*