[Combined liver resection and radiofrequency ablation for colorectal liver metastases].
BACKGROUND
Liver resection in combination with radiofrequency ablation (RFA) is a novel approach in patients with colorectal liver metastases who are otherwise unresectable.


METHODS
Eighteen patients with colorectal liver metastases were treated with surgical resection combined with RFA. All patients were followed prospectively with CT-scanning of thorax and abdomen during a 5-year period, 1, 4, 8 and 12 months after treatment and every 6 months thereafter for the following 4 years. Main outcome was recurrence and survival.


RESULTS
Eleven male and 7 female patients with a median age of 65 years (41-78) were treated with combined surgery and RFA. 76 metastases were treated, 34 of these with resection. The median survival rate in the entire group was 35 months. 5-years overall survival was 34%. 12 patients had recurrence and were treated with multimodality therapy.


CONCLUSIONS
Combined surgery and RFA treatment was a good alternative in a group of patients with colorectal liver metastases that were otherwise only suitable for systemic chemotherapy.
Kannerup
Anne-Sofie
AS
Arhus Universitetshospital, Arhus Sygehus, Kirurgisk Gastroenterologisk Afdeling L, Arhus. askannerup@gmail.com
Nielsen
Dennis Tømrer
DT
Sørensen
Steen Mellerup
SM
Mortensen
Frank Viborg
FV
D000328:Adult; D000368:Aged; D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011446:Prospective Studies; D016019:Survival Analysis