Fetal loss after amniocentesis in a series of 5,780 procedures.
OBJECTIVE
Counseling on prenatal diagnosis requires accurate knowledge of the associated risks, including fetal loss. The objective of our study was to assess this risk of amniocentesis in a single center with several operators.


METHODS
This retrospective analysis concerns only women with singleton pregnancies who underwent amniocentesis between 14(+0) and 23(+6) weeks' gestation.


RESULTS
During this 4.5-year period, 5,780 amniocenteses were performed, of which we analyzed 5,319. The rate of fetal loss was 70 in 4,858 tests (1.4%), with a lost-to-follow-up rate of 3.8%.


CONCLUSIONS
Our results for fetal loss are comparable to those in the largest series with fewer operators already published.
Gaudry
P
P
Department of Obstetrics and Gynecology, Hôpital d'Instruction des Armées Begin, Saint-Mandé, France.
Grangé
G
G
Lebbar
A
A
Choiset
A
A
Girard
S
S
Goffinet
F
F
Lewin
F
F
D000293:Adolescent; D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D015331:Cohort Studies; D005260:Female; D005313:Fetal Death / Q000453:epidemiology / Q000209:etiology*; D046689:Fetal Mortality; D005602:France / Q000453:epidemiology; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012307:Risk Factors