title: Intramuscular recurrence in a hepatocellular carcinoma patient with indolent disease course.
abstract: BACKGROUND
  Hepatocellular carcinoma (HCC) is a common malignancy worldwide and treatment options are depended on the stage of the tumour. In general, the prognosis of HCC patients with extra-hepatic metastasis is poor. The most common sites of extra-hepatic metastasis are the lung, abdominal lymph nodes and bone.
  
  
  METHODS
  Here, we reported a 54-year-old man with an indolent clinical course of HCC. He had multiple extra-hepatic recurrences after initial hepatectomy for HCC and was benefited from repeated resections with prolonged survival. Eventually, he developed intramuscular recurrence in the thigh, which was initially mistaken as deep vein thrombosis.
  
  
  CONCLUSIONS
  Selected patients with indolent disease course of HCC may benefit from repeated resections of extra-hepatic metastases with prolonged survival.
authors.affiliation: University Department of Surgery, Queen Mary Hospital, University of Hong Kong, Hong Kong. the@netvigator.com
authors.forename: Thomas
authors.initials: T
authors.lastname: Yau
authors.forename: Hilda
authors.initials: H
authors.lastname: Wong
authors.forename: Pierre
authors.initials: P
authors.lastname: Chan
authors.forename: Mc
authors.initials: M
authors.lastname: To
authors.forename: Ronnie T
authors.initials: RT
authors.lastname: Poon
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000556:secondary / Q000628:therapy*; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000556:secondary / Q000628:therapy*; D012086:Reoperation; D013848:Thigh