title: [Genetic polymorphism of glutathione-s-transferases theta1 and mu1 in lung cancer].
abstract: Polymorphism of GSTT1 and GSTM1 variant genes of phase II biotransformation of xenobiotics was studied in 181 patients with lung cancer. Null genotype frequency in cancer patients was higher than in healthy subjects. It was still higher in metastatic cancer disseminated to the regional lymph nodes as compared with localized tumor.
authors.forename: A I
authors.initials: AI
authors.lastname: Dmitrieva
authors.forename: N V
authors.initials: NV
authors.lastname: Sevost'ianova
authors.forename: S A
authors.initials: SA
authors.lastname: Kolomiets
authors.forename: S B
authors.initials: SB
authors.lastname: Tkachenko
authors.forename: N A
authors.initials: NA
authors.lastname: Davydova
authors.forename: O V
authors.initials: OV
authors.lastname: Cheremisina
authors.forename: V V
authors.initials: VV
authors.lastname: Novitskiĭ
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic
chemical_list: D014408:Biomarkers, Tumor; D005982:Glutathione Transferase; C413545:glutathione S-transferase T1