Overview of methods for assessing the mouse auditory system.
The three general approaches for assessing the mouse auditory system presented in UNITS 8.21B-8.21D are complementary, but differ in the time required for testing as well as the goals of the tests: the auditory brainstem response (ABR; UNIT 8.21B), distortion product otoacoustic emissions (DPOAE; UNIT 8.21C), and lick suppression behavioral test (UNIT 8.21D). Various issues that need to be addressed in the testing of mouse hearing are discussed in this overview, including accurate nomenclature of the strain and/or mutations, environmental versus genetic influences, selection of frequencies to be tested, and appropriate animal care and use.
Willott
James F
JF
University of South Florida and The Jackson Laboratory, Tampa, Florida, USA.
D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D001306:Auditory Pathways / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D051379:Mice; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*