Radiation dose, driving performance, and cognitive function in patients with head and neck cancer.
Seven head and neck cancer patients participated in a driving evaluation in a driving simulator. Radiation dose on the temporal lobes was moderately associated with time to complete a cognitive test and with driving performance. Results indicated that incidental irradiation may contribute to a decrease in cognition and in unsafe driving performance, which seems to be time-dependent.
Yuen
Hon K
HK
College of Health Professions, Medical University of South Carolina, Charleston, South Carolina 29425, USA. yuen@musc.edu
Sharma
Anand K
AK
Logan
William C
WC
Gillespie
M Boyd
MB
Day
Terry A
TA
Brooks
Johnell O
JO
D000328:Adult; D000368:Aged; D001334:Automobile Driving; D003071:Cognition / Q000528:radiation effects*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D013702:Temporal Lobe / Q000528:radiation effects*