title: The angiotensin converting enzyme insertion/deletion polymorphism and differences in fasting plasma glucose in Hindustani Surinamese, African Surinamese and ethnic Dutch: the population-based SUNSET-study.
abstract: We investigated the association between the angiotensin converting enzyme (ACE) insertion/deletion polymorphism and glycemic state. Diabetes mellitus, impaired fasting glucose and mean fasting glucose were not associated with genotype among Hindustani Surinamese, African Surinamese and Dutch participants. Our results cast (further) doubts on the association between ACE and glycemic state.
authors.affiliation: Department of Social Medicine, Academic Medical Centre, University of Amsterdam, J2-207 Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. I.G.vanValkengoed@amc.uva.nl
authors.forename: Irene G M
authors.initials: IG
authors.lastname: van Valkengoed
authors.forename: Karien
authors.initials: K
authors.lastname: Stronks
authors.forename: Ines N
authors.initials: IN
authors.lastname: Hahntow
authors.forename: Joost B L
authors.initials: JB
authors.lastname: Hoekstra
authors.forename: Frits
authors.initials: F
authors.lastname: Holleman
mesh_terms: D000328:Adult; D000349:Africa / Q000208:ethnology; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000201:enzymology* / Q000235:genetics; D005215:Fasting; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D016254:Mutagenesis, Insertional; D009426:Netherlands; D007703:Peptidyl-Dipeptidase A / Q000172:deficiency / Q000235:genetics*; D011110:Polymorphism, Genetic; D017384:Sequence Deletion; D013532:Suriname / Q000208:ethnology
chemical_list: D001786:Blood Glucose; D007703:Peptidyl-Dipeptidase A