title: [The use of coaxil (tianeptine) in the treatment of aged people with combined mild cognitive impairment and depressive-anxiety disorders].
abstract: Twenty patients, aged 60-69 years, with combined mild cognitive impairment, subtle depression and anxiety have been treated with coaxil (tianeptine) used in dosage 37,5 mg daily during 60 days. The clinical state of patients has been assessed using clinical-psychopathological examination as well as the Hamilton scale and neuropsychological testing according to A.R. Luria. The high effectiveness of coaxil is revealed with respect to all psychopathological characteristics. Recommendations on expediency of administering coaxil to aged patients with combined cognitive and depressive disorders are presented.
authors.forename: I B
authors.initials: IB
authors.lastname: Karpukhin
mesh_terms: D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000453:epidemiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D013841:Thiazepines / Q000627:therapeutic use*
chemical_list: D000929:Antidepressive Agents, Tricyclic; D013841:Thiazepines; C050504:tianeptine