Fire in the hole: pore dilation of the capsaicin receptor TRPV1.
Bautista
Diana
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Julius
David
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D000818:Animals; D002211:Capsaicin / Q000494:pharmacology; D002463:Cell Membrane Permeability / Q000187:drug effects / Q000235:genetics; D006801:Humans; D006930:Hyperalgesia / Q000235:genetics / Q000378:metabolism*; D018836:Inflammation Mediators / Q000494:pharmacology; D015640:Ion Channel Gating / Q000187:drug effects / Q000502:physiology*; D007477:Ions / Q000378:metabolism; D008958:Models, Molecular; D020078:Neurogenic Inflammation / Q000139:chemically induced / Q000378:metabolism / Q000503:physiopathology; D009619:Nociceptors / Q000187:drug effects / Q000378:metabolism*; D010146:Pain / Q000235:genetics / Q000378:metabolism* / Q000503:physiopathology; D011984:Sensory Receptor Cells / Q000187:drug effects / Q000378:metabolism*; D018689:Sensory System Agents / Q000494:pharmacology; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology; D050916:TRPV Cation Channels / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*
D018836:Inflammation Mediators; D007477:Ions; D018689:Sensory System Agents; D050916:TRPV Cation Channels; C493921:TRPV1 protein, mouse; D002211:Capsaicin