title: Optic disc hemorrhages in a patient with hemophilia A.
abstract: To report a hemophilia patient complicated with optic disc hemorrhages. A 13-year-old boy presented to our emergency room with a black shadow in the left eye for 1 day. The best-corrected visual acuity was 6/6 in both eyes. Peripapillary retinal and subretinal hemorrhages were found in the left eye. Result of the laboratory examination showed an extremely low level of coagulation factor VIII (1.9%). Factor VIII concentrate was given for 8 weeks. A follow-up 3 months later showed absorption of the hemorrhages, black shadow diminished, and the vision was 6/6.
authors.affiliation: Department of Ophthalmology, Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd, Taipei, 114, Taiwan, ROC.
authors.forename: Teng-Yi
authors.initials: TY
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Kaohsiung Armed Force General Hospital, Kaohsiung, Taiwan, ROC.
authors.forename: Chi-Ting
authors.initials: CT
authors.lastname: Horng
authors.affiliation: Department of Pediatrics, Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan, ROC.
authors.forename: Shin-Nan
authors.initials: SN
authors.lastname: Cheng
authors.affiliation: Department of Ophthalmology, Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd, Taipei, 114, Taiwan, ROC.
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd, Taipei, 114, Taiwan, ROC.
authors.forename: Jiann-Torng
authors.initials: JT
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd, Taipei, 114, Taiwan, ROC. doc30845@yahoo.com.tw.
authors.forename: Ming-Ling
authors.initials: ML
authors.lastname: Tsai
mesh_terms: D000293:Adolescent; D005169:Factor VIII / Q000008:administration & dosage*; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000097:blood / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009901:Optic Nerve Diseases / Q000097:blood / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D014785:Vision, Ocular / Q000187:drug effects*
chemical_list: C078147:F8 protein, human; D005169:Factor VIII