[Study on molluscicidal effect of chlorosalicylicamide].
OBJECTIVE
To observe the molluscicidal effect of chlorosalicylicamide on Oncomelania hupensis and toxicity on fishes.


METHODS
Different concentrations of chlorosalicylicamide were prepared, and immersion and spraying methods were used to test its molluscicidal effect and toxicity to fishes. Niclosamide ethanolamine salt was used as control.


RESULTS
Under water temperature of 28 C with the dose of chlorosalicylicamide at 0.25 mg/L and 0.4 mg/L, the mortality rate of snails by immersion was 97.8% and 100% respectively after 48 h, and the LC50 was 0.0674 mg/L. While for niclosamide at the same doses, the mortality rate of snails was 22.2% and 66.7% respectively, and the LC50 was 0.397 6 mg/L. With the concentration of 0.4 mg/L for 72 h, the fish death rate in chlorosalicylicamide and niclosamide was 50.0% and 100% respectively.


CONCLUSIONS
Chlorosalicylicamide shows a molluscicidal effect on Oncomelania snails and a lower toxicity to fishes than that of niclosamide.
Jin
Wei
W
Department of Chemistry and Chemical Industry, Huazhong University of Science and Technology, Wuhan 430030, China.
Du
Jin-kui
JK
Yuan
Yi
Y
Wei
Feng-hua
FH
Liu
Wei
W
Wang
Hui
H
Li
Gui-ling
GL
Xu
Xing-jian
XJ
D000818:Animals; D004305:Dose-Response Relationship, Drug; D008975:Molluscacides / Q000494:pharmacology*; D009534:Niclosamide / Q000494:pharmacology*; D012908:Snails / Q000187:drug effects*
D008975:Molluscacides; D009534:Niclosamide