title: Long-standing fever and Angelman syndrome: report of two cases.
abstract: An 8-month-old girl and a 20-month-old boy who presented with motor and developmental delay and long-standing fever are presented. The patients were diagnosed as Angelman syndrome with fluorescence in situ hybridization (FISH) analysis. Despite extensive clinical and laboratory examinations, no inflammatory or infectious origin for the fever was found. It was considered that the long-standing fever observed in these cases was due to hypothalamic dysfunction for thermoregulation.
authors.forename: Uluç
authors.initials: U
authors.lastname: Yiş
authors.forename: Ozlem
authors.initials: O
authors.lastname: Giray
authors.forename: Semra H
authors.initials: SH
authors.lastname: Kurul
authors.forename: Elçin
authors.initials: E
authors.lastname: Bora
authors.forename: Ayfer
authors.initials: A
authors.lastname: Ulgenalp
authors.forename: Derya
authors.initials: D
authors.lastname: Erçal
authors.forename: Eray
authors.initials: E
authors.lastname: Dirik
mesh_terms: D017204:Angelman Syndrome / Q000175:diagnosis / Q000503:physiopathology; D001833:Body Temperature Regulation; D002658:Developmental Disabilities; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D017404:In Situ Hybridization, Fluorescence; D007223:Infant; D008297:Male; D014421:Turkey