title: Triazolylpyrenes: synthesis, fluorescence properties, and incorporation into DNA.
abstract: Synthesis of 1,6- and 1,8-triazolylpyrenes and their incorporation into oligonucleotides is described. In hybrids, triazolylpyrenes adopt interstrand stacking interactions. Exciton coupling is observed for the duplex containing a pair of the 1,6-isomer indicating a well-defined helical arrangement of the triazolylpyrene building blocks. Triazole substitution results in pronounced red-shifts of monomer as well as excimer fluorescence. Furthermore, quantum yields of the formed excimers are remarkably high.
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
authors.forename: Sarah
authors.initials: S
authors.lastname: Werder
authors.forename: Vladimir L
authors.initials: VL
authors.lastname: Malinovskii
authors.forename: Robert
authors.initials: R
authors.lastname: Häner
mesh_terms: D004247:DNA / Q000737:chemistry*; D005453:Fluorescence; D007364:Intercalating Agents / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D011721:Pyrenes / Q000138:chemical synthesis* / Q000737:chemistry*; D013696:Temperature; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D007364:Intercalating Agents; D011721:Pyrenes; D014230:Triazoles; D004247:DNA