The developmental toxicity of 1-methyl-3-octylimidazolium bromide on Daphnia magna.
The developmental toxicity of 1-methyl-3-octylimidazolium bromide ([C(8)mim]Br) on Daphnia magna was investigated. The 24 and 48 h LC(50) values for [C(8)mim]Br in D. magna were 1.99 and 0.95 mg/L, respectively. A series of multigenerational toxicity tests were then used to explore [C(8)mim]Br effects in D. magna. [C(8)mim]Br significantly inhibited the body lengths of the F0 and F1 1st generations. After 21 days of exposure, [C(8)mim]Br lowered the reproductive ability of the F0 and F1 1st generations. In F1 3rd generation, 21 days of [C(8)mim]Br exposure prolonged the time to bear the first egg and the time to the first brood compared with the control, but the number of first-brood offspring and the number of broods produced by these animals were reduced. After the recovery period all the reproductive parameters returned to normal in F1 1st generation except for the number of broods. The dead neonates increased with prolonged exposure and increasing concentrations, and the dead neonates of the F1 3rd generation went far beyond that of the F1 1st and F0 generations. The intrinsic rate of natural increase (r) values of the three D. magna generations significantly decreased after exposure to higher concentrations of [C(8)mim]Br compared with control groups. Collectively, these results suggest that [C(8)mim]Br exerts a toxic effect on the development of D. magna. This study also highlights the importance of systematically evaluating the potential effects of aquatic ecosystems of ionic liquids that may be released into bodies of water.
Luo
Yan-Rui
YR
College of Resources and Environmental Sciences, China Agricultural University, Beijing 100094, China.
Li
Xiao-Yu
XY
Chen
Xiao-Xiao
XX
Zhang
Bang-Jun
BJ
Sun
Zhen-Jun
ZJ
Wang
Jian-Ji
JJ
D000818:Animals; D000831:Animals, Newborn; D049628:Body Size / Q000187:drug effects* / Q000502:physiology; D003621:Daphnia / Q000187:drug effects* / Q000254:growth & development / Q000502:physiology*; D017753:Ecosystem; D007093:Imidazoles / Q000378:metabolism / Q000633:toxicity*; D052578:Ionic Liquids / Q000378:metabolism / Q000633:toxicity; D012098:Reproduction / Q000187:drug effects / Q000502:physiology; D013997:Time Factors; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000378:metabolism / Q000633:toxicity*
C534649:1-methyl-3-octylimidazolium bromide; D007093:Imidazoles; D052578:Ionic Liquids; D014874:Water Pollutants, Chemical