MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features.
Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options.
Monroe
Matthew E
ME
Pacific Northwest National Laboratory, Richland, WA 99354, USA. matthew.monroe@pnl.gov
Shaw
Jason L
JL
Daly
Don S
DS
Adkins
Joshua N
JN
Smith
Richard D
RD
D000465:Algorithms; D002853:Chromatography, Liquid / Q000379:methods; D003198:Computer Simulation; D013058:Mass Spectrometry / Q000379:methods*; D010455:Peptides / Q000737:chemistry*; D012984:Software
D010455:Peptides