title: Granulomatous reaction in mediastinal B-cell non-Hodgkin lymphoma and intracardiac thrombosis.
abstract: Epithelioid cell granulomas may be associated with several neoplasms. Lymphomas may mimic or are associated with epithelioid granulomas. In this article the authors report a child with granulomatous reaction in B cell non-Hodgkin lymphoma and intracardiac thrombosis. Although cancer alone is a risk factor for thromboembolism, thrombosis is a multifactorial disorder with both hereditary and acquired risk factors. This is the first reported case of intracardiac thrombosis with MTHFR A1298C and factor XIII V34L mutations together with granulomatous reaction in non-Hodgkin lymphoma.
authors.affiliation: Department of Pediatric Oncology, Kocaeli University, Kocaeli, Turkey. fundacorapcioglu@yahoo.com
authors.forename: Funda
authors.initials: F
authors.lastname: Corapçioglu
authors.forename: Eviç Zeynep
authors.initials: EZ
authors.lastname: Basar
authors.forename: Atalay
authors.initials: A
authors.lastname: Demirel
authors.forename: Nagihan
authors.initials: N
authors.lastname: Inan
authors.forename: Kadir
authors.initials: K
authors.lastname: Babaoğlu
authors.forename: Hasan
authors.initials: H
authors.lastname: Karakurt
authors.forename: Evrim
authors.initials: E
authors.lastname: Kus
authors.forename: Gorkem
authors.initials: G
authors.lastname: Aksu
mesh_terms: D019943:Amino Acid Substitution; D002648:Child; D005176:Factor XIII / Q000235:genetics; D006099:Granuloma / Q000150:complications* / Q000235:genetics / Q000473:pathology; D006331:Heart Diseases / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000235:genetics / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000556:secondary; D020125:Mutation, Missense; D013927:Thrombosis / Q000209:etiology* / Q000235:genetics / Q000473:pathology
chemical_list: D005176:Factor XIII