title: Apoptosis pathways in fungal growth, development and ageing.
abstract: Apoptosis is one type of programmed cell death with great importance for development and homeostasis of multicellular organisms. Unexpectedly, during the past decade, evidence has been obtained for the existence of a basal apoptosis machinery in yeast, as unicellular fungus, and in some filamentous fungi, a group of microorganisms that are neither true unicellular nor true multicellular biological systems but something in between. Here, we review evidence for a role of apoptotic processes in fungal pathogenicity, competitiveness, propagation, ageing and lifespan control.
authors.affiliation: Institute for Molecular Biosciences, Department of Biosciences and Cluster of Excellence Macromolecular Complexes, J.W. Goethe-University, Max-von-Laue-Strasse 9, Frankfurt, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Hamann
authors.forename: Diana
authors.initials: D
authors.lastname: Brust
authors.forename: Heinz D
authors.initials: HD
authors.lastname: Osiewacz
mesh_terms: D017209:Apoptosis; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D005658:Fungi / Q000254:growth & development* / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D054884:Host-Pathogen Interactions; D006801:Humans; D016897:Respiratory Burst; D015398:Signal Transduction
chemical_list: D005656:Fungal Proteins