Measurement of natural killer cell progenitor activity in culture.
Natural killer cells are morphologically related to and have progenitors in common with B and T lymphocytes. In this unit, protocols describe how to induce natural killer cell differentiation from prolymphocytes. Since NK cell differentiation cultures also support B cell differentiation, this protocol is extremely useful for seeking the B and NK cell branch point in their differentiation pathway.
Kouro
Taku
T
Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
Yokota
Takafumi
T
Welner
Robert
R
Kincade
Paul W
PW
D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D019411:Clinical Laboratory Techniques; D007694:Killer Cells, Natural / Q000166:cytology*; D051379:Mice; D013234:Stem Cells / Q000166:cytology*