Mock circulatory system for the evaluation of left ventricular assist devices, endoluminal prostheses, and vascular diseases.
A new digital computer mock circulatory system has been developed in order to replicate the physiologic and pathophysiologic characteristics of the human cardiovascular system. The computer performs the acquisition of pressure, flow, and temperature in an open loop system. A computer program has been developed in Labview programming environment to evaluate all these physical parameters. The acquisition system was composed of pressure, flow, and temperature sensors and also signal conditioning modules. In this study, some results of flow, cardiac frequencies, pressures, and temperature were evaluated according to physiologic ventricular states. The results were compared with literature data. In further works, performance investigations will be conducted on a ventricular assist device and endoprosthesis. Also, this device should allow for evaluation of several kinds of vascular diseases.
Legendre
Daniel
D
Institute Dante Pazzanese of Cardiology, Escola Politécnica, University of São Paulo, Brazil. daniel.legendre@poli.usp.br
Fonseca
Jeison
J
Andrade
Aron
A
Biscegli
José Francisco
JF
Manrique
Ricardo
R
Guerrino
Domingos
D
Prakasan
Akash Kuzhiparambil
AK
Ortiz
Jaime Pinto
JP
Lucchi
Julio Cesar
JC
D001775:Blood Circulation / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001807:Blood Vessel Prosthesis; D002319:Cardiovascular System / Q000503:physiopathology; D003187:Compliance; D003198:Computer Simulation; D045268:Flowmeters; D006339:Heart Rate / Q000502:physiology; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D012212:Rheology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D012984:Software; D013696:Temperature; D014652:Vascular Diseases / Q000503:physiopathology; D014655:Vascular Resistance / Q000502:physiology; D014783:Viscosity