Evidence for a cross-linking mechanism underlying glucose-induced contraction of phenylboronate hydrogel.
The glucose-dependent cross-linking of phenylboronate gels was investigated in order to understand the principle underlying glucose-induced hydrogel contraction. Glucose conformation upon binding to phenylboronates in aqueous solution was also examined and a 1:2 glucofuranose: boronate model was suggested by the results obtained.
Pan
Xiaohan
X
Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK.
Yang
Xiaoping
X
Lowe
Christopher R
CR
D015374:Biosensing Techniques; D001709:Biotechnology; D001897:Boronic Acids / Q000737:chemistry*; D002236:Carbohydrate Conformation; D003432:Cross-Linking Reagents; D005947:Glucose / Q000737:chemistry*; D006696:Holography; D020100:Hydrogels / Q000737:chemistry; D008958:Models, Molecular; D012996:Solutions; D014867:Water
D001897:Boronic Acids; D003432:Cross-Linking Reagents; D020100:Hydrogels; D012996:Solutions; D014867:Water; D005947:Glucose; C010686:benzeneboronic acid