A convenient stereochemical notation for p-chiral nucleotide analogs.
The D(P)/L(P) convention is a stereochemical notation for P-chiral nucleotide analogs and related compounds. In contrast to the absolute R(P)/S(P) notation, the D(P)/L(P) system is based on a geometrical relationship between substituents in a dinucleoside monophosphate skeleton. The D(P)/L(P) notation is a convenient alternative to the R(P)/S(P) notation for stereochemical correlation analysis of physical, chemical, and biological properties of nucleotide and oligonucleotide analogs bearing any type of tri- or tetra-coordinated phosphorus moiety.
Sobkowski
Michal
M
Institute of Bioorganic Chemistry, Poznan, Poland.
Stawinski
Jacek
J
Kraszewski
Adam
A
D008024:Ligands; D009711:Nucleotides / Q000737:chemistry*; D013237:Stereoisomerism
D008024:Ligands; D009711:Nucleotides