title: Effect of thirty days of creatine supplementation with phosphate salts on anaerobic working capacity and body weight in men.
abstract: The purpose of this study was to determine the effect of 30 days of single-dose creatine supplementation with phosphate salts (CPS) on body weight (BW) and anaerobic working capacity (AWC) in men. Using a double-blind design, 32 men randomly received 1 serving of either CPS (5 g Cr + 4 g phosphate) (n = 17) or 20 g of dextrose as placebo (PL) (n = 15) for 30 days. AWC determined from the Critical Power Test and BW were measured at baseline, 10 days, 20 days, 30 days, and 10 days post-supplementation. Results (2 x 5 ANOVA) showed no significant differences between groups for AWC at any time point; however, BW was significantly increased at 10 days in the CPS group (1.0 kg) vs. PL (0.0 kg), and remained elevated for the duration of the study. These findings suggest that a single 5 g x d(-1) dose of CPS for 30 days increases BW but is not effective for increasing AWC in men.
authors.affiliation: Department of Exercise Science, Creighton University, Omaha, Nebraska, USA. eckerson@creighton.edu
authors.forename: Joan M
authors.initials: JM
authors.lastname: Eckerson
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Bull
authors.forename: Geri A
authors.initials: GA
authors.lastname: Moore
mesh_terms: D000328:Adult; D015308:Anaerobic Threshold / Q000187:drug effects; D000704:Analysis of Variance; D001835:Body Weight / Q000187:drug effects*; D019587:Dietary Supplements; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000502:physiology; D010725:Phosphocreatine / Q000008:administration & dosage*; D010806:Physical Education and Training / Q000379:methods; D010807:Physical Endurance / Q000187:drug effects*; D011336:Probability; D012016:Reference Values; D012680:Sensitivity and Specificity
chemical_list: D010725:Phosphocreatine