title: Models of neuropathic pain in the rat.
abstract: There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.
authors.affiliation: McGill University, Montreal, Quebec, Canada.
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Bennett
authors.forename: Jin Mo
authors.initials: JM
authors.lastname: Chung
authors.forename: Marie
authors.initials: M
authors.lastname: Honore
authors.forename: Ze'ev
authors.initials: Z
authors.lastname: Seltzer
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000379:methods*; D003250:Constriction; D004195:Disease Models, Animal; D008026:Ligation; D008297:Male; D009437:Neuralgia / Q000209:etiology*; D009488:Neurosciences / Q000379:methods*; D059348:Peripheral Nerve Injuries; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000293:injuries; D013127:Spinal Nerves / Q000293:injuries; D013997:Time Factors; D014947:Wounds and Injuries / Q000150:complications