title: Idiopathic premature closure of the ductus arteriosus: an indication for early delivery.
abstract: Idiopathic intrauterine closure of the ductus arteriosus, distinct from intrauterine constriction associated with maternal NSAID ingestion or other secondary causes, is an uncommon event that often results in significant morbidity and mortality. We report on a 32-week fetus with meconium pseudocyst that presented with idiopathic intrauterine constriction of the ductus arteriosus, and review the literature. We suggest that early diagnosis and judicious obstetrical management, in conjunction with pediatric cardiology consultation based on serial fetal echocardiography, can lead to timely delivery and reversal of the pathophysiology providing the potential for a favorable outcome.
authors.affiliation: Division of Pediatric Cardiology, Vanderbilt Children's Hospital, Nashville, Tennessee, USA.
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Soslow
authors.forename: Mark K
authors.initials: MK
authors.lastname: Friedberg
authors.forename: Norman H
authors.initials: NH
authors.lastname: Silverman
mesh_terms: D004374:Ductus Arteriosus, Patent / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D047928:Premature Birth; D016216:Ultrasonography, Prenatal / Q000379:methods*