title: Synthesis of ribonucleosides by condensation using trimethylsilyl triflate.
abstract: This unit describes, in detail, the optimized condition for the synthesis of nucleosides making use of the trimethysilyl triflate-mediated silyl-Hilbert-Johnson synthesis. This unit focuses on the mechanistic understanding of this universal and conveniently applicable method.
authors.affiliation: Free University Berlin, Berlin, Germany.
authors.forename: Helmut
authors.initials: H
authors.lastname: Vorbrüggen
authors.forename: Irene M
authors.initials: IM
authors.lastname: Lagoja
authors.forename: Piet
authors.initials: P
authors.lastname: Herdewijn
mesh_terms: D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D012263:Ribonucleosides / Q000138:chemical synthesis*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: D012263:Ribonucleosides; D014297:Trimethylsilyl Compounds