title: Therapeutic criteria in communicating childhood hydrocephalus.
abstract: OBJECTIVE
  The aim of this study was to evaluate the usefulness of cerebral blood flow velocity in the middle cerebral artery measured by transcranial Doppler as criteria to therapeutic action in communicating hydrocephalic children.
  
  
  METHODS
  In eight non-tumoral communicating hydrocephalic infants, ranging from five to 18 months of age, monitored from 18 to 36 months (mean time of follow-up: 24.25 months), cerebrospinal fluid (CSF) oxypurines (hypoxanthine and xanthine) and uric acid levels were compared by means of the Evans' index, the mean weekly increase in cranial circumference, and the transcranial Doppler measurements.
  
  
  RESULTS
  Results indicate that clinical (mean weekly increase in head circumference), radiological (Evans' index), biochemical (oxypurines and uric acid in the CSF), and hemodynamic (transcranial Doppler) criteria have the same role in monitoring infantile hydrocephalus.
  
  
  CONCLUSIONS
  In conclusion the transcranial Doppler measurement can be done noninvasively and examinations can be repeated when needed, obtaining immediate
  
  
  RESULTS
  Hence, it is the most adequate monitoring technique in clinical practice.
authors.affiliation: Department of Pediatrics, Neuropediatric Service, University Hospital , Santiago de Compostela, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Nuñez
authors.forename: M
authors.initials: M
authors.lastname: Somoza-Martín
authors.forename: C
authors.initials: C
authors.lastname: Gómez-Lado
authors.forename: J
authors.initials: J
authors.lastname: Eirís-Puñal
authors.forename: F
authors.initials: F
authors.lastname: Camiña-Darriba
authors.forename: S
authors.initials: S
authors.lastname: Rodríguez-Segade
authors.forename: M
authors.initials: M
authors.lastname: Castro-Gago
mesh_terms: D001783:Blood Flow Velocity; D049628:Body Size; D002560:Cerebrovascular Circulation; D006257:Head / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000628:therapy*; D019271:Hypoxanthine / Q000134:cerebrospinal fluid; D007223:Infant; D017585:Ultrasonography, Doppler, Transcranial; D014527:Uric Acid / Q000134:cerebrospinal fluid; D019820:Xanthine / Q000134:cerebrospinal fluid
chemical_list: D019820:Xanthine; D014527:Uric Acid; D019271:Hypoxanthine