IDT SciTools: a suite for analysis and design of nucleic acid oligomers.
DNA and RNA oligomers are used in a myriad of diverse biological and biochemical experiments. These oligonucleotides are designed to have unique biophysical, chemical and hybridization properties. We have created an integrated set of bioinformatics tools that predict the properties of native and chemically modified nucleic acids and assist in their design. Researchers can select PCR primers, probes and antisense oligonucleotides, find the most suitable sequences for RNA interference, calculate stable secondary structures, and evaluate the potential for two sequences to interact. The latest, most accurate thermodynamic algorithms and models are implemented. This free software is available at http://www.idtdna.com/SciTools/SciTools.aspx.
Owczarzy
Richard
R
Department of Molecular Genetics and Biophysics, Integrated DNA Technologies, Inc., 1710 Commercial Park, Coralville, IA 52241, USA. science@owczarzy.net
Tataurov
Andrey V
AV
Wu
Yihe
Y
Manthey
Jeffrey A
JA
McQuisten
Kyle A
KA
Almabrazi
Hakeem G
HG
Pedersen
Kent F
KF
Lin
Yuan
Y
Garretson
Justin
J
McEntaggart
Neil O
NO
Sailor
Chris A
CA
Dawson
Robert B
RB
Peek
Andrew S
AS
D017931:DNA Primers / Q000737:chemistry; D020407:Internet; D009690:Nucleic Acid Conformation; D015345:Oligonucleotide Probes / Q000737:chemistry; D009841:Oligonucleotides / Q000737:chemistry*; D016376:Oligonucleotides, Antisense / Q000737:chemistry; D034741:RNA, Small Interfering / Q000737:chemistry; D012984:Software
D017931:DNA Primers; D015345:Oligonucleotide Probes; D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense; D034741:RNA, Small Interfering; C477371:locked nucleic acid