title: Is asthma in childhood different from asthma in adults? Why do we need special approaches to asthma in children?
abstract: Childhood asthma poses a number of challenges. In many asthmatic patients, the disease begins in infancy or early childhood and aeroallergen sensitization in the first 3 years of life appears to dictate later outcomes. The airway manifestations of asthma in childhood differ from those in adults and require different therapeutic approaches. Importantly, corticosteroid treatment of childhood asthma appears to have little impact on the progressive loss of lung function in a subset of patients.
authors.affiliation: Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA. gelfande@njc.org
authors.forename: Erwin W
authors.initials: EW
authors.lastname: Gelfand
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000375:Aging; D000485:Allergens / Q000276:immunology; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007223:Infant
chemical_list: D000305:Adrenal Cortex Hormones; D000485:Allergens; D018927:Anti-Asthmatic Agents; D016207:Cytokines