title: A new tandem repeat in bovine fibrinogen Aalpha gene.
abstract: In this study, we describe intraspecies variation in the alphaC connector region of the bovine fibrinogen Aalpha gene. Sequencing and genotyping of six bovine breeds revealed 7 to 10 tandem repeats in the alphaC connector region. In addition, we observed length differences between B. indicus and B. taurus, with the B. indicus having longer fibrinogen alphaC connectors (10-repeat alleles) than B. taurus (7- and 9-repeats). The difference in tandem repeats may be related to the function of blood coagulation system.
authors.affiliation: Laboratory of Animal Breeding and Genetics, Graduate School of Agricultural Science, Kobe University, Kobe, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Inaba
authors.forename: Kei
authors.initials: K
authors.lastname: Tsurifune
authors.forename: Shinji
authors.initials: S
authors.lastname: Sasazaki
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Mannen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D004247:DNA / Q000737:chemistry / Q000235:genetics; D005340:Fibrinogen / Q000235:genetics*; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012150:Polymorphism, Restriction Fragment Length; D016415:Sequence Alignment; D020080:Tandem Repeat Sequences
chemical_list: C464794:fibrinogen Aalpha; D005340:Fibrinogen; D004247:DNA