Asymmetric synthesis of beta-lactams using chiral-memory effect on photochemical gamma-hydrogen abstraction by thiocarbonyl group.
Optically active beta-lactams were synthesized via photochemical intramolecular gamma-hydrogen abstraction reaction of thioimides involving a highly-controlled chiral-memory effect.
Sakamoto
Masami
M
Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University, Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan. sakamotom@faculty.chiba-u.jp
Kawanishi
Hiroya
H
Mino
Takashi
T
Fujita
Tsutomu
T
D006859:Hydrogen / Q000737:chemistry*; D008968:Molecular Conformation; D010777:Photochemistry; D013237:Stereoisomerism; D013854:Thioamides / Q000737:chemistry* / Q000528:radiation effects; D014466:Ultraviolet Rays; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry
D013854:Thioamides; D047090:beta-Lactams; D006859:Hydrogen