title: Solvent-impregnated resins as an in situ product recovery tool for phenol recovery from Pseudomonas putida S12TPL fermentations.
abstract: The sustainable production of fine/bulk chemicals is often hampered by product toxicity and inhibition to the producing micro-organisms. Consequently, the product must be removed from the micro-organisms' environment. To achieve this, so-called solvent-impregnated resins (SIRs) as well as commercial resins have been added to a Pseudomonas putida S12TPL fermentation that produces phenol as a model compound from glucose. The SIRs contained an ionic liquid which extracts phenol effectively. It was observed that the addition of these particles resulted in an increased phenol production of more than a fourfold while the commercial resin (XAD-4) which is widely used in aromatic removal from aqueous phases, only gave a 2.5-fold increase in volumetric production.
authors.affiliation: TNO, Laan van Westenenk 501, Apeldoorn, 7334 DT, Gelderland, The Netherlands. corjan.vandenberg@tno.nl
authors.forename: Corjan
authors.initials: C
authors.lastname: van den Berg
authors.forename: Nick
authors.initials: N
authors.lastname: Wierckx
authors.forename: Johan
authors.initials: J
authors.lastname: Vente
authors.forename: Paul
authors.initials: P
authors.lastname: Bussmann
authors.forename: Jan
authors.initials: J
authors.lastname: de Bont
authors.forename: Luuk
authors.initials: L
authors.lastname: van der Wielen
mesh_terms: D020003:1-Octanol / Q000737:chemistry; D000327:Adsorption; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D007218:Industrial Microbiology / Q000379:methods*; D019800:Phenol / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D010721:Phosphinic Acids / Q000737:chemistry; D011137:Polystyrenes / Q000737:chemistry; D011145:Polyvinyls / Q000737:chemistry; D016958:Pseudomonas putida / Q000254:growth & development* / Q000378:metabolism*; D012117:Resins, Synthetic / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D010721:Phosphinic Acids; D011137:Polystyrenes; D011145:Polyvinyls; D012117:Resins, Synthetic; D012997:Solvents; D019800:Phenol; C012101:XAD-4 resin; D005947:Glucose; D020003:1-Octanol