title: QSAR study of mosquito repellents from terpenoid with a six-member-ring.
abstract: A new class of low-toxicity mosquito repellents is synthesized from alpha- and beta-pinene in terpenoid compounds and preliminary biological tests show promising mosquito repellency. Statistical modeling is built using Codessa in order to reveal the quantitative relationship between the structure and the biological activity and to provide the guidance for further synthetic work.
authors.affiliation: College of Forestry, Jiangxi Agricultural University, Nanchang 330045, China.
authors.forename: Zongde
authors.initials: Z
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Song
authors.forename: Jinzhu
authors.initials: J
authors.lastname: Chen
authors.forename: Zhanqian
authors.initials: Z
authors.lastname: Song
authors.forename: Shibin
authors.initials: S
authors.lastname: Shang
authors.forename: Zhikuan
authors.initials: Z
authors.lastname: Jiang
authors.forename: Zhaojiu
authors.initials: Z
authors.lastname: Han
mesh_terms: D000818:Animals; D000081008:Bicyclic Monoterpenes; D001733:Bites and Stings / Q000517:prevention & control*; D001643:Bridged Bicyclo Compounds; D009033:Culicidae / Q000187:drug effects*; D007302:Insect Repellents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D008956:Models, Chemical; D039821:Monoterpenes / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use*; D021281:Quantitative Structure-Activity Relationship
chemical_list: D000081008:Bicyclic Monoterpenes; D001643:Bridged Bicyclo Compounds; D007302:Insect Repellents; D039821:Monoterpenes; C010789:beta-pinene; C005451:alpha-pinene