Schizophrenia: genome, interrupted.
Structural chromosomal variation is increasingly recognized as an important contributor to human diseases, particularly those of neurodevelopment, such as autism. A current paper makes a significant advance to schizophrenia genetics by establishing an association with rare copy number variants (CNV), which are over-represented in neurodevelopmental genes.
Cantor
Rita M
RM
Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Geschwind
Daniel H
DH
D016678:Genome / Q000235:genetics*; D006801:Humans; D012559:Schizophrenia / Q000235:genetics*