title: Wnt signaling in somite development.
abstract: During vertebrate embryogenesis, specialized mesodermal structures, called somites, give rise to a variety of mesodermal tissues including skeletal muscles, vertebrae and dermis. Development of the somites is a rhythmic process that involves a series of steps including segmentation of the paraxial mesoderm, epithelialization, somite formation, somite maturation, somite patterning and differentiation of somitic cells into different lineages. Wnt signaling has been found to play crucial roles in multiple steps of somite development. In this review, we present a brief overview of current knowledge on Wnt signaling events during the development of somites and their derivatives.
authors.affiliation: Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany. poongo_3@yahoo.com
authors.forename: Poongodi
authors.initials: P
authors.lastname: Geetha-Loganathan
authors.forename: Suresh
authors.initials: S
authors.lastname: Nimmagadda
authors.forename: Martin
authors.initials: M
authors.lastname: Scaal
authors.forename: Ruijin
authors.initials: R
authors.lastname: Huang
authors.forename: Bodo
authors.initials: B
authors.lastname: Christ
mesh_terms: D000818:Animals; D019521:Body Patterning; D047108:Embryonic Development / Q000502:physiology*; D006801:Humans; D008648:Mesoderm / Q000502:physiology; D008855:Microscopy, Electron, Scanning; D015398:Signal Transduction; D051153:Wnt Proteins / Q000502:physiology* / Q000648:ultrastructure
chemical_list: D051153:Wnt Proteins