Carcinosarcomatous malignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur.
We report a new type of secondary malignant giant cell tumor of bone, the malignancy of which was assigned to a carcinosarcoma, i.e., osteosarcoma and squamous cell carcinoma. It occurred 25 years after curettage and bone graft surgery under the diagnosis of giant cell tumor of the right distal femur. Although secondary malignant giant cell tumor is known as a sarcoma arising at the site of a previously diagnosed giant cell tumor, this case should be regarded as a new type of secondary malignant giant cell tumor of bone.
Machinami
Rikuo
R
Department of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Ariake 3-10-6, Kouto-ku, Tokyo 135-8550, Japan. machinami-tky@umin.ac.jp
Nishida
Kazunori
K
Ishida
Tsuyoshi
T
Matsumoto
Seiichi
S
Kuroda
Kouji
K
Kobayashi
Masafumi
M
Takeuchi
Kengo
K
Ishikawa
Yuichi
Y
D000671:Amputation, Surgical; D016025:Bone Transplantation; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002296:Carcinosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003475:Curettage; D017809:Fatal Outcome; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D009626:Terminology as Topic