title: Mock circulatory system for the evaluation of left ventricular assist devices, endoluminal prostheses, and vascular diseases.
abstract: A new digital computer mock circulatory system has been developed in order to replicate the physiologic and pathophysiologic characteristics of the human cardiovascular system. The computer performs the acquisition of pressure, flow, and temperature in an open loop system. A computer program has been developed in Labview programming environment to evaluate all these physical parameters. The acquisition system was composed of pressure, flow, and temperature sensors and also signal conditioning modules. In this study, some results of flow, cardiac frequencies, pressures, and temperature were evaluated according to physiologic ventricular states. The results were compared with literature data. In further works, performance investigations will be conducted on a ventricular assist device and endoprosthesis. Also, this device should allow for evaluation of several kinds of vascular diseases.
authors.affiliation: Institute Dante Pazzanese of Cardiology, Escola Politécnica, University of São Paulo, Brazil. daniel.legendre@poli.usp.br
authors.forename: Daniel
authors.initials: D
authors.lastname: Legendre
authors.forename: Jeison
authors.initials: J
authors.lastname: Fonseca
authors.forename: Aron
authors.initials: A
authors.lastname: Andrade
authors.forename: José Francisco
authors.initials: JF
authors.lastname: Biscegli
authors.forename: Ricardo
authors.initials: R
authors.lastname: Manrique
authors.forename: Domingos
authors.initials: D
authors.lastname: Guerrino
authors.forename: Akash Kuzhiparambil
authors.initials: AK
authors.lastname: Prakasan
authors.forename: Jaime Pinto
authors.initials: JP
authors.lastname: Ortiz
authors.forename: Julio Cesar
authors.initials: JC
authors.lastname: Lucchi
mesh_terms: D001775:Blood Circulation / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001807:Blood Vessel Prosthesis; D002319:Cardiovascular System / Q000503:physiopathology; D003187:Compliance; D003198:Computer Simulation; D045268:Flowmeters; D006339:Heart Rate / Q000502:physiology; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D012212:Rheology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D012984:Software; D013696:Temperature; D014652:Vascular Diseases / Q000503:physiopathology; D014655:Vascular Resistance / Q000502:physiology; D014783:Viscosity