title: [Histamine releasing activity of dental materials as the indicator of their biocompatibility].
abstract: Different types of dental materials (DM) were studied for their capacity to release histamine in vitro from basophils of whole blood of allergic patients and healthy donors using automated and computerized glass fiber-based leukocyte histamine release test (LHRT). It was shown that some types of DM possessed ability to release histamine from basophils and some didn't. There were no differences in histamine releaseability from basophils obtained from allergic patients and healthy donors. LHRT gives opportunity to recognize of DM possessing high or low histamine releaseability as well as to detect individual sensitivity to different DM. Thus, LHRT can be used for preliminary assessment of DM for their biocompatibility and also for individual selection of suitable DM for particular patient to avoid unwanted side effects.
authors.forename: A A
authors.initials: AA
authors.lastname: Babakhin
authors.forename: A I
authors.initials: AI
authors.lastname: Volozhin
authors.forename: L V
authors.initials: LV
authors.lastname: Dubova
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Lebedenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Babakhina
authors.forename: A A
authors.initials: AA
authors.lastname: Zhuravleva
authors.forename: L M
authors.initials: LM
authors.lastname: Diubuske
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D001491:Basophils / Q000378:metabolism*; D001672:Biocompatible Materials / Q000737:chemistry*; D003764:Dental Materials / Q000737:chemistry*; D006632:Histamine / Q000378:metabolism*; D006636:Histamine Release / Q000502:physiology*; D006801:Humans; D006967:Hypersensitivity / Q000097:blood; D008422:Materials Testing / Q000379:methods*; D013050:Spectrometry, Fluorescence
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials; D003764:Dental Materials; D006632:Histamine