title: A facile in situ generation of dithiocarbamate ligands for stable gold nanoparticle-oligonucleotide conjugates.
abstract: Here we demonstrate a facile strategy of preparing gold nanoparticle (AuNP) and DNA conjugates by in situ generation of strong metal affinity capping ligands, dithiocarbamates (DTC) modified oligonucleotides; the conjugates produced are stable at elevated temperature, resistant to ligand displacement and preserve the functionality of the conjugated oligonucleotides.
authors.affiliation: Department of Chemistry & Biochemistry and Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
authors.forename: Jaswinder
authors.initials: J
authors.lastname: Sharma
authors.forename: Rahul
authors.initials: R
authors.lastname: Chhabra
authors.forename: Hao
authors.initials: H
authors.lastname: Yan
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
mesh_terms: D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D053768:Metal Nanoparticles / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D013859:Thiocarbamates / Q000737:chemistry*
chemical_list: D008024:Ligands; D009841:Oligonucleotides; D013859:Thiocarbamates; D006046:Gold