Touch, sound and vision in human superior temporal sulcus.
Human superior temporal sulcus (STS) is thought to be a key brain area for multisensory integration. Many neuroimaging studies have reported integration of auditory and visual information in STS but less is known about the role of STS in integrating other sensory modalities. In macaque STS, the superior temporal polysensory area (STP) responds to somatosensory, auditory and visual stimulation. To determine if human STS contains a similar area, we measured brain responses to somatosensory, auditory and visual stimuli using blood-oxygen level dependent functional magnetic resonance imaging (BOLD fMRI). An area in human posterior STS, STSms (multisensory), responded to stimulation in all three modalities. STSms responded during both active and passive presentation of unisensory somatosensory stimuli and showed larger responses for more intense vs. less intense tactile stimuli, hand vs. foot, and contralateral vs. ipsilateral tactile stimulation. STSms showed responses of similar magnitude for unisensory tactile and auditory stimulation, with an enhanced response to simultaneous auditory-tactile stimulation. We conclude that STSms is important for integrating information from the somatosensory as well as the auditory and visual modalities, and could be the human homolog of macaque STP.
Beauchamp
Michael S
MS
Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA. Michael.S.Beauchamp@uth.tmc.edu <Michael.S.Beauchamp@uth.tmc.edu>
Yasar
Nafi E
NE
Frye
Richard E
RE
Ro
Tony
T
D000161:Acoustic Stimulation; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000502:physiology*; D014110:Touch / Q000502:physiology*; D014732:Vibration; D014796:Visual Perception / Q000502:physiology*