title: [Post-circumcision tetanus in Dakar, Senegal].
abstract: This study aimed at describing the epidemiology, clinical features and prognosis of post-circumcision tetanus at the infectious diseases clinic in Fann Hospital in Dakar. Data were collected retrospectively for analysis from patients' files recorded from January 1, 1999 to December 31, 2006. 54 cases were included, accounting for 4% of all tetanus cases admitted to the clinic during the study period (54 cases/1291). The patients' average age was 9 +/- 3.7 years old (range = 1-17 years) and 52% of them were schoolboys. In most cases (76%), tetanus symptoms occurred beyond 7 days after circumcision. The average delay from onset of the disease to admission was 2.3 days (range = 0-6 days). The circumcision took place at home in 39% of cases, in health center in 35% of cases and in unspecified area in 26% of cases. The majority of patients (85%) had never received tetanus vaccine and, in 72% of the cases, the circumciser was designated as a male nurse. Generalized tetanus was observed in all cases, most of which was a mild form of the disease (63%). During hospitalisation, thirteen patients (24%) had complications among which diaphragmatic and intercostal muscle spasms (3 cases), bacteraemia (5 cases), respiratory infection (4 cases), urinary tract infection (4 cases), and fracture of the vertebrae (1 case). The case fatality rate was 7.4% (4 deaths). Vaccination together with health education of the population as well as a better sensitization of the practitioners are necessary to eradicate tetanus after circumcision.
authors.affiliation: Clinique des maladies infectieuses, CHU de Fann, BP 5035 Dakar, Sénégal. soumarem@refer.sn
authors.forename: M
authors.initials: M
authors.lastname: Soumaré
authors.forename: M
authors.initials: M
authors.lastname: Seydi
authors.forename: N M
authors.initials: NM
authors.lastname: Dia
authors.forename: S A
authors.initials: SA
authors.lastname: Diop
authors.forename: C T
authors.initials: CT
authors.lastname: N'dour
authors.forename: L
authors.initials: L
authors.lastname: Diouf
authors.forename: B M
authors.initials: BM
authors.lastname: Diop
authors.forename: P S
authors.initials: PS
authors.lastname: Sow
mesh_terms: D000293:Adolescent; D000367:Age Factors; D016470:Bacteremia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002944:Circumcision, Male / Q000009:adverse effects / Q000706:statistics & numerical data*; D003964:Diaphragm / Q000473:pathology; D016021:Epidemiologic Studies; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007366:Intercostal Muscles / Q000473:pathology; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data; D011379:Prognosis; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012189:Retrospective Studies; D012675:Senegal / Q000453:epidemiology; D013035:Spasm / Q000453:epidemiology; D016103:Spinal Fractures / Q000453:epidemiology; D013742:Tetanus / Q000453:epidemiology* / Q000401:mortality; D013745:Tetanus Toxoid; D013997:Time Factors; D014552:Urinary Tract Infections / Q000453:epidemiology
chemical_list: D013745:Tetanus Toxoid