Facile fabrication of multi-colors high fluorescent/superparamagnetic nanoparticles.
We developed a novel method to prepare multi-colors high fluorescent/superparamagnetic nanoparticles (FMNPs) employing hydrophobic multi-color quantum dots (QDs) and hydrophobic Fe(3)O(4) (MNPs) via ultrasonic emulsification method. This structural procedure was simple, one-off, and timesaving. Different-sizes FMNPs with encoding single/multi-color QDs and MNPs were achieved. Analysis with transmission electron microscopy (TEM) and particle size analyzer demonstrated that the as-prepared samples were spherical, uniform in size distribution; Ultraviolet-visible (UV-vis) absorption spectroscopy and photoluminescence (PL) measurement showed the FMNPs had good optical properties, lacking of fluorescence resonance energy transfer (FRET) inside FMNPs; vibrating sample magnetometer (VSM) indicated that FMNPs were superparamagnetic. These results indicate that the as-prepared FMNPs have potential of serving as a hybrid of QDs and MNPs in bioanalysis communities.
Zhang
Bingbo
B
Institute of Nanobiotechnology, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, PR China.
Cheng
Jing
J
Gong
Xiaoqun
X
Dong
Xiaoqing
X
Liu
Xuhui
X
Ma
Guiping
G
Chang
Jin
J
D005456:Fluorescent Dyes / Q000737:chemistry; D049449:Luminescence; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology; D010316:Particle Size; D045663:Quantum Dots
D005456:Fluorescent Dyes