title: Ovarian signet-ring stromal tumor: a potential diagnostic pitfall.
abstract: Signet-ring stromal tumor is a rare ovarian neoplasm with only 10 reported cases in the literature. We report an unusual case of ovarian signet-ring stromal tumor in a 69-year-old woman who presented with right adnexal mass and underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The diagnosis was based on histological, histochemical, immunohistochemical, and electron microscopy characteristics. The main significance is to differentiate this benign tumor from the highly malignant Krukenberg tumor, and this differential diagnosis is discussed.
authors.affiliation: Department of Pathology, Ben-Gurion University of the Negev, Beer-Sheva, Israel. rsl@bgu.ac.il
authors.forename: Ruthy
authors.initials: R
authors.lastname: Shaco-Levy
authors.forename: Leonid
authors.initials: L
authors.lastname: Kachko
authors.forename: Moshe
authors.initials: M
authors.lastname: Mazor
authors.forename: Benjamin
authors.initials: B
authors.lastname: Piura
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D018279:Carcinoma, Signet Ring Cell / Q000737:chemistry / Q000175:diagnosis* / Q000601:surgery; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007725:Krukenberg Tumor / Q000175:diagnosis; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000601:surgery; D017154:Stromal Cells / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor