title: Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state.
abstract: We demonstrate that in Listeria monocytogenes, temperature-responsive transcriptional control of flagellar genes does not rely on the phosphorylation of the conserved phosphorylation site (D55) in the receiver domain of response regulator DegU. Furthermore, proper control of DegU-regulated genes involved in ethanol tolerance and virulence is independent of receiver phosphorylation.
authors.affiliation: Theodor-Boveri-Institut für Biowissenschaften, Lehrstuhl für Mikrobiologie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.
authors.forename: Norman
authors.initials: N
authors.lastname: Mauder
authors.forename: Tatjana
authors.initials: T
authors.lastname: Williams
authors.forename: Frederike
authors.initials: F
authors.lastname: Fritsch
authors.forename: Michael
authors.initials: M
authors.lastname: Kuhn
authors.forename: Dagmar
authors.initials: D
authors.lastname: Beier
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D000431:Ethanol / Q000494:pharmacology; D005407:Flagella / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial / Q000187:drug effects; D008089:Listeria monocytogenes / Q000235:genetics / Q000502:physiology*; D010766:Phosphorylation / Q000187:drug effects; D016133:Polymerase Chain Reaction; D013696:Temperature
chemical_list: D001426:Bacterial Proteins; C066497:DegU protein, Bacteria; D000431:Ethanol