title: Conjugation of ATIII-binding pentasaccharides to extend the half-life of proteins: long-acting insulin.
authors.affiliation: Department of Medicinal Chemistry, N.V. Organon, part of Schering-Plough Corporation, Molenstraat 110, PO Box 20, 5340 BH, Oss, The Netherlands. m.dekort@organon.com
authors.forename: Martin
authors.initials: M
authors.lastname: de Kort
authors.forename: Bas
authors.initials: B
authors.lastname: Gianotten
authors.forename: Jeffry A J
authors.initials: JA
authors.lastname: Wisse
authors.forename: Ebo S
authors.initials: ES
authors.lastname: Bos
authors.forename: Michel H M
authors.initials: MH
authors.lastname: Eppink
authors.forename: Ellen
authors.initials: E
authors.lastname: Mattaar
authors.forename: Gerard M T
authors.initials: GM
authors.lastname: Vogel
authors.forename: Wim H A
authors.initials: WH
authors.lastname: Dokter
authors.forename: Maarten
authors.initials: M
authors.lastname: Honing
authors.forename: Stanislava
authors.initials: S
authors.lastname: Vonsovic
authors.forename: Martin-Jan
authors.initials: MJ
authors.lastname: Smit
authors.forename: Jac C H M
authors.initials: JC
authors.lastname: Wijkmans
authors.forename: Constant A A
authors.initials: CA
authors.lastname: van Boeckel
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000990:Antithrombin III / Q000737:chemistry*; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006207:Half-Life; D049528:Insulin, Long-Acting / Q000097:blood / Q000737:chemistry* / Q000494:pharmacology*; D008297:Male; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry*; D017434:Protein Structure, Tertiary; D051381:Rats; D017208:Rats, Wistar
chemical_list: D049528:Insulin, Long-Acting; D009844:Oligosaccharides; D000990:Antithrombin III