Naturally acquired human Plasmodium knowlesi infection, Singapore.
We report a case of naturally acquired Plasmodium knowlesi in Singapore, a malaria-free country. Diagnosis was confirmed by PCR with validated species-specific primers. In industrialized countries, free-ranging primates are a potential source of P. knowlesi human infection. P. knowlesi infection is a differential diagnosis of febrile illness acquired in Singapore.
Ng
Oon Tek
OT
Department of Infectious Disease, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. oon_tek_ng@ttsh.com.sg
Ooi
Eng Eong
EE
Lee
Cheng Chuan
CC
Lee
Piao Jarrod
PJ
Ng
Lee Ching
LC
Pei
Sze Wong
SW
Tu
Tian Ming
TM
Loh
Jin Phang
JP
Leo
Yee Sin
YS
D000328:Adult; D000818:Animals; D017931:DNA Primers; D016054:DNA, Protozoan / Q000032:analysis; D003937:Diagnosis, Differential; D005334:Fever / Q000175:diagnosis; D006801:Humans; D008251:Macaca / Q000469:parasitology; D008288:Malaria / Q000175:diagnosis* / Q000469:parasitology / Q000635:transmission*; D008297:Male; D008992:Monkey Diseases / Q000469:parasitology / Q000635:transmission*; D016790:Plasmodium knowlesi / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000379:methods; D012846:Singapore / Q000453:epidemiology; D013045:Species Specificity; D015047:Zoonoses / Q000469:parasitology / Q000635:transmission*
D017931:DNA Primers; D016054:DNA, Protozoan