title: Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.
abstract: A corona-charged aerosol detector (CAD) was developed to improve the sensitivity, reproducibility and quantitativeness of detection as compared to evaporative light-scattering detector (ELSD) for liquid chromatography. Our laboratory used the corona CAD as a detector for supercritical fluid chromatography (SFC) and evaluated its performance compared to the ELSD by using a certified reference material of poly(ethylene glycol) (PEG) and a well-defined equimass mixture of uniform PEG oligomers. The corona CAD was able to detect a 10 times more dilute solution of uniform oligomers compared to the ELSD. Although the original data of molecular mass by ELSD was 4.6% smaller than the certified value of PEG 1000, molecular mass distribution obtained by corona CAD was virtually almost the same as the certified value without any calibrations.
authors.affiliation: National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan. kayori.takahashi@ni.aist.go.jp
authors.forename: Kayori
authors.initials: K
authors.lastname: Takahashi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kinugasa
authors.forename: Masaaki
authors.initials: M
authors.lastname: Senda
authors.forename: Koki
authors.initials: K
authors.lastname: Kimizuka
authors.forename: Kyoko
authors.initials: K
authors.lastname: Fukushima
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shibata
authors.forename: John
authors.initials: J
authors.lastname: Christensen
mesh_terms: D000336:Aerosols / Q000737:chemistry*; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D008027:Light; D011108:Polymers / Q000032:analysis*; D012542:Scattering, Radiation
chemical_list: D000336:Aerosols; D011108:Polymers