title: IgM and avidity of IgG antibodies in primary HHV-6 infections.
abstract: Primary HHV-6 infection could be diagnosed by enzyme immunoassay from a single serum using IgG avidity test based on results obtained from 43 patients, 26 with seroconversion and 17 with variable antibody levels. The avidity was less than 30% in all patients with seroconversion. HHV-6 IgM appeared non-specific.
authors.affiliation: Department of Virology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital Laboratory Services, Helsinki, Finland.
authors.forename: Matteus J H
authors.initials: MJ
authors.lastname: Salonen
authors.forename: Antti
authors.initials: A
authors.lastname: Vaheri
authors.forename: Marjaleena
authors.initials: M
authors.lastname: Koskiniemi
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D000915:Antibody Affinity; D002648:Child; D002675:Child, Preschool; D015654:Herpesvirus 6, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000276:immunology*; D007223:Infant; D008875:Middle Aged; D019349:Roseolovirus Infections / Q000175:diagnosis / Q000276:immunology*; D012698:Serologic Tests / Q000379:methods
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M