title: Protein structure analysis online.
abstract: Computational biology/chemistry tools are used in most areas of life/health science research. These methods are continually being developed and their use can present difficulties for both experienced and novice investigators. To facilitate the use of these applications, many packages have been implemented online during these last 5 years. This unit focuses on online computational methods with a special emphasis on structural refinement/atomic simulations, protein electrostatic calculations, searches for functional sites, searches for druggable pockets, protein docking and small molecule docking, and prediction of potential impact of amino acid variations on the structure and function of the protein molecules.
authors.affiliation: Inserm U648, University of Paris, Paris, France.
authors.forename: Maria A
authors.initials: MA
authors.lastname: Miteva
authors.forename: Emil
authors.initials: E
authors.lastname: Alexov
authors.forename: Bruno O
authors.initials: BO
authors.lastname: Villoutreix
mesh_terms: D000465:Algorithms; D018360:Crystallography, X-Ray; D030562:Databases, Protein; D020407:Internet; D011487:Protein Conformation; D055672:Static Electricity