title: [Dimensionality and neurocognitive symptoms in OCD].
abstract: Obsessive-compulsive disorder (OCD) is composed of heterogenous phenomenological symptoms. The genetic background is proved but not described in detail; thus it seems to advantageous clustering the symptoms into groups, also called dimensions. The 71 items of the Y-BOCS symptom list have been subdivided in several ways. A subdivision system of 5 different factors in OCD has been proposed recently for the DSM-V instead of the 3 factor model of the DSM-IV used today (I. predominantly obsessive/ II. predominantly compulsive/ III. mixed subgroup). These factors as endophenotypes are supposed to be transmitted by common genetical pathways. Subdivision of the OCD by factors helps us to reveal the relation between subgroups of gender, age of onset of the disease, comorbid illnesses, and the responsivity to treatment. This approach of dimensionality is also useful in understanding the neurocognitive differences experienced in OCD. This is why we summarised up-to-date findings of the neurocognitive deficits connected to the affected brain areas in OCD: OFC, DLPFC, ACC, striatum, amygdala, thalamus. Finally the cognitive domains affected in OCD are summarised, such as: memory, planning, decision making, response inhibition, set-shifting, and attention deficits.
authors.affiliation: Nyiro Gyula Kórház, II. Pszichiátriai Osztaly, Budapest, Hungary. harsanyia@gmail.com
authors.forename: András
authors.initials: A
authors.lastname: Harsányi
authors.forename: Katalin
authors.initials: K
authors.lastname: Csigó
authors.forename: Gyula
authors.initials: G
authors.lastname: Demeter
authors.forename: Attila
authors.initials: A
authors.lastname: Németh
authors.forename: Mihály
authors.initials: M
authors.lastname: Racsmány
mesh_terms: D001288:Attention; D003657:Decision Making; D006801:Humans; D007266:Inhibition, Psychological; D008568:Memory; D009771:Obsessive-Compulsive Disorder / Q000523:psychology*; D011340:Problem Solving; D012718:Set, Psychology