title: Perinatal risk factors and mode of delivery correlated to survival and psychomotor disability in extremely low birth weight infants.
abstract: OBJECTIVE
  Extreme preterm birth, <28 weeks of gestation, represents a public health concern with major economic implications, being the leading cause of neonatal mortality and morbidity.
  
  
  METHODS
  A single-centre retrospective cohort study was carried out to assess the role of caesarean section and to identify perinatal factors affecting neonatal survival and psychomotor development in these infants. 57 cases with complete maternal, obstetrical and neonatological information were selected for this study and neurological development was assessed for at least 18 months of life.
  
  
  RESULTS
  Infant survival and neurological morbidity rates were directly and inversely correlated to birth weights and gestational age at birth, respectively. In multivariate analysis only extreme prematurity (<or=25 weeks) and birth weight <500 g were significantly associated with mortality, whereas no factor correlated to neuromotor impairment.
  
  
  CONCLUSIONS
  The management of preterm labour at the limit of viability is always challenging. Knowledge of risk factors associated with obstetrical situations may affect medical management and indeed offer useful information for parent counselling.
authors.affiliation: Department of Gynaecology, Obstetrics and Neonatology, University of Medical Science of Bari, Bari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Vimercati
authors.forename: M
authors.initials: M
authors.lastname: Scioscia
authors.forename: E
authors.initials: E
authors.lastname: Panella
authors.forename: C
authors.initials: C
authors.lastname: Nardelli
authors.forename: A
authors.initials: A
authors.lastname: Coluccia
authors.forename: C
authors.initials: C
authors.lastname: Camporeale
authors.forename: L
authors.initials: L
authors.lastname: DeCosmo
authors.forename: N
authors.initials: N
authors.lastname: Laforgia
authors.forename: L
authors.initials: L
authors.lastname: Selvaggi
mesh_terms: D000328:Adult; D001724:Birth Weight; D015331:Cohort Studies; D036861:Delivery, Obstetric / Q000379:methods; D005260:Female; D005865:Gestational Age; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011247:Pregnancy; D011596:Psychomotor Disorders / Q000209:etiology*; D012189:Retrospective Studies; D016019:Survival Analysis