Asymmetric total synthesis of antiochic acid.
The first asymmetric total synthesis of antiochic acid using bioinspired polyene cyclization strategy is described. Both good yield and good asymmetric induction were obtained.
Zhao
Yu-Jun
YJ
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore.
Loh
Teck-Peng
TP
D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D011090:Polyenes / Q000138:chemical synthesis* / Q000737:chemistry
D004224:Diterpenes; D011090:Polyenes; C530328:antiochic acid