Using CorePromoter to find human core promoters.
The CorePromoter program is very useful for identification of transcriptional start sites (TSS) and core promoter regions when 5'-upstream genomic DNA sequences of human genes are available. It is very simple to use and can be accessed either through the Web or after downloading to a local computer. The protocols in this unit introduce its basic methodology and discuss how to apply it to a sample problem in conjunction with other gene-finding programs.
Zhang
Michael Q
MQ
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D004247:DNA / Q000235:genetics*; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D011401:Promoter Regions, Genetic / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D024363:Transcription Initiation Site
D004247:DNA