title: Visceral fat thickness predicts fatty liver in Koreans with type 2 diabetes mellitus.
abstract: Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Yongdong Severance Hospital, 146-92 Dogok-dong, Gangnam-gu, Seoul, Korea.
authors.forename: Hai Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Min Ho
authors.initials: MH
authors.lastname: Cho
authors.forename: Jong Suk
authors.initials: JS
authors.lastname: Park
authors.forename: Ji Sun
authors.initials: JS
authors.lastname: Nam
authors.forename: Eun Seok
authors.initials: ES
authors.lastname: Kang
authors.forename: Chul Woo
authors.initials: CW
authors.lastname: Ahn
authors.forename: Bong Soo
authors.initials: BS
authors.lastname: Cha
authors.forename: Eun Jig
authors.initials: EJ
authors.lastname: Lee
authors.forename: Sung Kil
authors.initials: SK
authors.lastname: Lim
authors.forename: Kyung Rae
authors.initials: KR
authors.lastname: Kim
authors.forename: Hyun Chul
authors.initials: HC
authors.lastname: Lee
authors.forename: Kap Bum
authors.initials: KB
authors.lastname: Huh
mesh_terms: D000368:Aged; D001011:Aorta / Q000473:pathology; D015331:Cohort Studies; D048909:Diabetes Complications / Q000175:diagnosis*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000473:pathology; D005234:Fatty Liver / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D016017:Odds Ratio; D012372:ROC Curve; D012680:Sensitivity and Specificity