Sono-thermal oxidation of dihydropyrimidinones.
Combination of ultrasound and heat has been used for the oxidation of some ethyl 3,4-dihydropyrimidin-2(1H)-one-5-carboxylates to their corresponding ethyl pyrimidin-2(1H)-one-5-carboxylates by using potassium peroxydisulfate in aqueous acetonitrile. An ultrasonic probe of 24 kHz frequency has been used for this study. Whereas the use of ultrasound increases the rate of reactions compared with reactions at reflux conditions, the nature of 4-substituent on the dihydropyrimidinone ring affects also the rate of reaction.
Memarian
Hamid Reza
HR
University of Isfahan, Faculty of Science, Department of Chemistry, 81746-73441 Isfahan, Iran. memarian@sci.ui.ac.ir
Farhadi
Asadollah
A
D006358:Hot Temperature; D007202:Indicators and Reagents; D016877:Oxidants; D010084:Oxidation-Reduction; D017680:Potassium Compounds / Q000737:chemistry; D011744:Pyrimidinones / Q000737:chemistry* / Q000528:radiation effects*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013431:Sulfates / Q000737:chemistry; D014465:Ultrasonics
D007202:Indicators and Reagents; D016877:Oxidants; D017680:Potassium Compounds; D011744:Pyrimidinones; D013431:Sulfates; C009007:potassium persulfate