title: [Prevalence of cervical spine inflammatory changes in rheumatoid arthritis patients and the value of neurological examination in their diagnosis].
abstract: The aim of the study was to evaluate prevalence of cervical spine inflammatory changes, especially atlantoaxial pathology, and their possible relation to subjective and objective neurological symptoms in rheumatoid arthritis patients. 100 patients (88 female and 12 male) aged 23 to 85 (61.4 +/- 12.9), with the mean disease duration of 12.5 +/- 9.5 years were included in the study. According to radiological examination (lateral and antero-posterior X-ray of the cervical spine) supplemented by MR of the cervical spine or CT of the atlanto-axial joint in suspected cases, 26% of patients had only inflammation, next 15% of patients presented with instability of the atlanto-axial joint and 9% developed basilar invagination of the dens of axis. 18% of patients presented subaxial cervical instability. Neurological examitation was performed by independent neurologist in 99 patients, only 14 presented abnormalities suggesting cervical myelopathy. Two of them showed no patology of the cervical spine. Remaining patients presented: C1/C2 inflammation in 4 cases, anterior atlanto-axial subluxation (AAS) in two cases, basilar invagination in 4 cases and instability with medullary compression on lower cervical levels only--in two cases. There were 4 cases of coexisting C1/C2 changes with medullary compression due to discopathy and (in 3 of them) instability on lower cervical levels. In 6 cases surgical stabilisation was proposed (5 patients with basilar invagination and 1 patient with AAS and myelopathy). There was statistically significant correlation between symptoms (like: paraesthesiae, intermittent problems with hearing and seeing), neurological examination and degree of radiological damage of atlanto-axial joint. The authors concluded that careful medical history and neurological examination can be useful in making decision of further radiological diagnostic procedures of the cervical spine in rheumatoid arthritis.
authors.affiliation: Klinika Chorób Wewnetrznych i Reumatologii CSK MON WIM, Warszawa. apapierska@poczta.wp.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Raczkiewicz-Papierska
authors.forename: Artur
authors.initials: A
authors.lastname: Bachta
authors.forename: Ewa
authors.initials: E
authors.lastname: Nagańska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Zagrodzka
authors.forename: Ewa
authors.initials: E
authors.lastname: Skrobowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Tłustochowicz
authors.forename: Anna
authors.initials: A
authors.lastname: Dudek
authors.forename: Witold
authors.initials: W
authors.lastname: Tłustochowicz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology*; D001268:Atlanto-Axial Joint / Q000000981:diagnostic imaging; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D015995:Prevalence; D011859:Radiography; D013166:Spondylitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology*