title: Control strategies for highly pathogenic avian influenza: a global perspective.
abstract: Comprehensive programmes for the prevention, detection and control of highly pathogenic avian influenza (HPAI) require a national dimension and relevant national legislation in which veterinary services can conduct surveillance, competent diagnosis and rapid response. Avian influenza was controlled and prevented by vaccination long before the current H5N1 crisis. The use of vaccine cannot be separated from other essential elements of a vaccination campaign, which include education in poultry production practices, such as hygiene, all in-all out production concepts, separation of species, biosecurity (bio-exclusion to keep the disease out and biocontainment to keep the disease from spreading once suspected or detected), competence in giving the vaccine and the role of vaccination teams, post-vaccination monitoring to ensure efficacy and to detect the circulation of wild-type virus, surveillance and buffer zones in outbreak areas, and performance indicators to determine when vaccination can cease. Reporting of disease can be improved through well-structured, adequately financed veterinary services and also by fair compensation for producers who suffer financial loss. A rapid response to suspected cases of HPAI should be ensured in simulation exercises involving various sectors of the food production and marketing chain, policy-makers, official veterinary structures and other government personnel. As for other transboundary animal diseases, national approaches must be part of a regional strategy and regional networks for cooperation and information sharing, which in turn reflect global policies and international standards, such as the quality of vaccines, reporting obligations, humane interventions, cleaning and disinfection methods, restocking times, monitoring and safe trade.
authors.affiliation: Emergency Prevention System for Transboundary Animal Pests and Plant Diseases, Animal Health Service, Animal Production and Health Division, Food and Agriculture Organization of the United Nations, Rome, Italy. juan.lubroth@fao.org
authors.forename: J
authors.initials: J
authors.lastname: Lubroth
mesh_terms: D000818:Animals; D001717:Birds; D003132:Commerce; D003140:Communicable Disease Control / Q000191:economics / Q000379:methods* / Q000458:organization & administration*; D014943:Global Health; D053124:Influenza A Virus, H5N1 Subtype; D007252:Influenza Vaccines / Q000276:immunology; D005585:Influenza in Birds / Q000453:epidemiology* / Q000517:prevention & control* / Q000821:virology; D007391:International Cooperation; D007886:Legislation, Veterinary; D009313:National Health Programs / Q000458:organization & administration
chemical_list: D007252:Influenza Vaccines