title: [Preparation of total matrine controlled release micropellet capsules].
abstract: OBJECTIVE
  To prepare total matrine controlled release micropellet capsules.
  
  
  METHODS
  The capsules were prepared by the technology of film-coating with surelease as matrix, and judged by the release behavior.
  
  
  RESULTS
  The drug had completely been coated into a homogeneous and continuous film, and the results repeated in three batches showed that the release behavior of the pellet capsules followed zero-equation.
  
  
  CONCLUSIONS
  The capsules have good sustained release effect and the process of the preparation is available.
authors.affiliation: Department of Pharmarcy, Guangzhou University of Chinese Medicine, Guangzhou 510045, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Shi
authors.forename: Yi
authors.initials: Y
authors.lastname: Cheng
authors.forename: Xue-tao
authors.initials: XT
authors.lastname: Li
mesh_terms: D000470:Alkaloids / Q000008:administration & dosage / Q000737:chemistry* / Q000493:pharmacokinetics; D002482:Cellulose / Q000737:chemistry; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems; D008863:Microspheres; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D011807:Quinolizines / Q000008:administration & dosage / Q000737:chemistry* / Q000493:pharmacokinetics; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D029909:Sophora / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000379:methods*; D014867:Water; D000093842:Matrines
chemical_list: D000470:Alkaloids; D003692:Delayed-Action Preparations; D011108:Polymers; D011807:Quinolizines; D012997:Solvents; D014867:Water; D002482:Cellulose; D000093842:Matrines