title: MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features.
abstract: Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options.
authors.affiliation: Pacific Northwest National Laboratory, Richland, WA 99354, USA. matthew.monroe@pnl.gov
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Monroe
authors.forename: Jason L
authors.initials: JL
authors.lastname: Shaw
authors.forename: Don S
authors.initials: DS
authors.lastname: Daly
authors.forename: Joshua N
authors.initials: JN
authors.lastname: Adkins
authors.forename: Richard D
authors.initials: RD
authors.lastname: Smith
mesh_terms: D000465:Algorithms; D002853:Chromatography, Liquid / Q000379:methods; D003198:Computer Simulation; D013058:Mass Spectrometry / Q000379:methods*; D010455:Peptides / Q000737:chemistry*; D012984:Software
chemical_list: D010455:Peptides