title: Commonly used mouse strains.
abstract: This appendix lists commonly used mouse strains and selected cell-surface molecules expressed by these strains. H-2 is the gene locus residing on chromosome 17 of the mouse which encodes major histocompatibility proteins. Only those H-2 loci involved in immunologic interactions frequently cited in this manual are listed here--i.e., Aa-, Ab-, Ea-, and Eb--region-encoded MHC class II molecules, and K-and D-region-encoded MHC class I molecules. In addition to H-2 loci, others are listed that encode immunologically important proteins. Congenic strains listed in this appendix represent inbred strains that were derived from their origin (BALB/c, C57Bl/10, and C3H) by selective matings, such that they differ from that originating strain at only one independently segregating genetic locus. The locus of choice in these cases was H-2; thus, these strains differ from their strain of origin only in their H-2 complex, but not in any other loci. During the production of the congenic lines, several strains were derived that had undergone intra-H-2 recombination events. These strains are listed here and have been invaluable in defining the major roles of various MHC glycoproteins.
authors.affiliation: Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors.forename: A M
authors.initials: AM
authors.lastname: Kruisbeek
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000235:genetics*; D033481:Chromosomes, Mammalian / Q000235:genetics*; D005802:Genes, MHC Class II / Q000235:genetics*; D006183:H-2 Antigens / Q000235:genetics* / Q000276:immunology; D008565:Membrane Proteins / Q000235:genetics* / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics* / Q000276:immunology; D013045:Species Specificity
chemical_list: D015703:Antigens, CD; D006183:H-2 Antigens; D008565:Membrane Proteins