title: Novel markers of inflammation in atherosclerosis.
abstract: Inflammation plays a key role in the pathogenesis of atherosclerosis. Understanding the process of inflammation as it pertains to atherosclerosis has provided researchers with multiple opportunities to identify novel markers for use in cardiovascular disease management. This article discusses the inflammatory cascade as it pertains to atherosclerosis and some of the well-studied markers of inflammation. It also discusses the limitations of current risk stratification models and characteristics of a good biomarker.
authors.affiliation: Department of Medicine, Baylor College of Medicine, 6565 Fannin, M.S.A-601, Houston, TX 77030, USA.
authors.forename: Salim S
authors.initials: SS
authors.lastname: Virani
authors.forename: Venkateshwar R
authors.initials: VR
authors.lastname: Polsani
authors.forename: Vijay
authors.initials: V
authors.lastname: Nambi
mesh_terms: D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase / Q000502:physiology; D019540:Area Under Curve; D015415:Biomarkers / Q000032:analysis*; D002097:C-Reactive Protein / Q000032:analysis; D003324:Coronary Artery Disease / Q000097:blood* / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000503:physiopathology; D009195:Peroxidase / Q000097:blood / Q000502:physiology; D012372:ROC Curve; D018570:Risk Assessment
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein; D009195:Peroxidase; D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase