title: Hepatic splenosis preoperatively diagnosed as hepatocellular carcinoma in a patient with chronic hepatitis B: a case report.
abstract: We report on a case of hepatic splenosis. A 32-yr-old man underwent a splenectomy due to trauma at the age of 6. He had been diagnosed as being a chronic hepatitis B-virus carrier 16 yr prior to the surgery. The dynamic computer tomography (CT) performed due to elevated serum alpha-fetoprotein (128 ng/mL) demonstrated two hepatic nodules, which were located near the liver capsule. A nodule in Segment IVa had a slight enhancement during both the arterial and portal phases, and another nodule in Segment VI showed a slight enhancement only in the portal phases. Dynamic magnetic resonance imaging (MRI) of the mass in Segment VI showed enhanced development in the arterial phases and slight hyperintensivity to the liver parenchyma in the portal phases. These imaging findings suggested a hypervascular tumor in the liver, which could be either focal nodular hyperplasia, adenoma, or hepatocellular carcinoma (HCC). Even though these lesions were diagnosed as HCC, some of the findings were not compatible with typical HCC. On dynamic CT and MRI, all lesions showed a slight arterial enhancement and did not show early venous washout. All lesions were located near the liver capsule. These findings, along with a history of splenectomy, suggested a diagnosis of hepatic splenosis.
authors.affiliation: Department of Surgery, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, Korea. choi5491@yuhs.sc
authors.forename: Gi-Hong
authors.initials: GH
authors.lastname: Choi
authors.forename: Man-Ki
authors.initials: MK
authors.lastname: Ju
authors.forename: June-Young
authors.initials: JY
authors.lastname: Kim
authors.forename: Chang-Moo
authors.initials: CM
authors.lastname: Kang
authors.forename: Kyung-Sik
authors.initials: KS
authors.lastname: Kim
authors.forename: Jin-Sub
authors.initials: JS
authors.lastname: Choi
authors.forename: Kwang-Hyub
authors.initials: KH
authors.lastname: Han
authors.forename: Mi-Suk
authors.initials: MS
authors.lastname: Park
authors.forename: Young-Nyun
authors.initials: YN
authors.lastname: Park
authors.forename: Woo-Jung
authors.initials: WJ
authors.lastname: Lee
authors.forename: Byong-Ro
authors.initials: BR
authors.lastname: Kim
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D020518:Focal Nodular Hyperplasia / Q000175:diagnosis / Q000473:pathology; D019694:Hepatitis B, Chronic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D017890:Splenosis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000096:biosynthesis
chemical_list: D000509:alpha-Fetoproteins