Cell expansion and maintenance of stemness.
Manipulation of hematopoietic cells to expand output while maintaining stem-cell potential has been an elusive goal of experimental hematology. The development of a system using a chemically induced dimerizer and modified thrombopoietin receptor has now allowed the expansion of primitive hematopoiesis without sacrificing stem cells.
Kaushansky
Kenneth
K
University of California at San Diego,USA.