title: The effect of a chlorhexidine containing cavity disinfectant on the clinical performance of high-viscosity glass-ionomer cement following ART: 24-month results.
abstract: OBJECTIVE
  To evaluate the effect of a chlorhexidine-gluconate-based cavity disinfectant on the clinical performance of high viscosity glass-ionomer cement following the ART approach under field conditions after 24 months.
  
  
  METHODS
  126 school children 6-8 years old who had bilateral matched pairs of carious Class I and II primary molars were included. A split mouth design was used in which Ketac Molar was randomly placed with or without the use of chlorhexidine-gluconate-based cavity disinfectant on contralateral sides by three dentists. The restorations were evaluated after 6, 12 and 24 months by two experienced examiners using USPHS-Ryge criteria.
  
  
  RESULTS
  The 24-month mean cumulative survival rates of Ketac Molar without the use of disinfectant were 97.7% and 69.4% while in the disinfectant group, the survival rates were 95.2% and 63.9% in Class I and II restorations, respectively with no significant difference between the groups in both class types. In the non-disinfected group, large Class II cavities had significantly better survival rates than did small Class II cavities (P = 0.023). In the disinfected group, the failure rates in mean cumulative survivals from 6 to 12 months and 12 to 24 months significantly increased with time (P = 0.004 and P = 0.016 respectively).
authors.affiliation: Department of Pediatric Dentistry, Ege University, Bornova-Izmir 35100, Turkey. nazan.ersin@ege.edu.tr
authors.forename: Nazan Kocatas
authors.initials: NK
authors.lastname: Ersin
authors.forename: Arzu
authors.initials: A
authors.lastname: Aykut
authors.forename: Umit
authors.initials: U
authors.lastname: Candan
authors.forename: Ozant
authors.initials: O
authors.lastname: Onçağ
authors.forename: Cemal
authors.initials: C
authors.lastname: Eronat
authors.forename: Timur
authors.initials: T
authors.lastname: Kose
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D016022:Case-Control Studies; D002648:Child; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003116:Color; D001840:Dental Bonding; D003731:Dental Caries / Q000628:therapy; D003737:Dental Cavity Preparation / Q000379:methods*; D018772:Dental Marginal Adaptation; D019232:Dental Restoration Failure; D003793:Dental Restoration, Permanent / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005899:Glass Ionomer Cements / Q000737:chemistry*; D006801:Humans; D008297:Male; D008963:Molar / Q000473:pathology; D012008:Recurrence; D013499:Surface Properties; D016019:Survival Analysis; D014094:Tooth, Deciduous / Q000473:pathology
chemical_list: D000891:Anti-Infective Agents, Local; D005899:Glass Ionomer Cements; C110712:ketac-molar; C010882:chlorhexidine gluconate; D002710:Chlorhexidine