The angiotensin converting enzyme insertion/deletion polymorphism and differences in fasting plasma glucose in Hindustani Surinamese, African Surinamese and ethnic Dutch: the population-based SUNSET-study.
We investigated the association between the angiotensin converting enzyme (ACE) insertion/deletion polymorphism and glycemic state. Diabetes mellitus, impaired fasting glucose and mean fasting glucose were not associated with genotype among Hindustani Surinamese, African Surinamese and Dutch participants. Our results cast (further) doubts on the association between ACE and glycemic state.
van Valkengoed
Irene G M
IG
Department of Social Medicine, Academic Medical Centre, University of Amsterdam, J2-207 Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. I.G.vanValkengoed@amc.uva.nl
Stronks
Karien
K
Hahntow
Ines N
IN
Hoekstra
Joost B L
JB
Holleman
Frits
F
D000328:Adult; D000349:Africa / Q000208:ethnology; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000201:enzymology* / Q000235:genetics; D005215:Fasting; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D016254:Mutagenesis, Insertional; D009426:Netherlands; D007703:Peptidyl-Dipeptidase A / Q000172:deficiency / Q000235:genetics*; D011110:Polymorphism, Genetic; D017384:Sequence Deletion; D013532:Suriname / Q000208:ethnology
D001786:Blood Glucose; D007703:Peptidyl-Dipeptidase A