title: GBR and autogenous cortical bone particulate by bone scraper for alveolar ridge augmentation: a 2-case report.
abstract: Scientific literature describes autogenous bone as the gold standard among graft materials for alveolar reconstructive procedures. Alveolar ridge augmentation has been clinically achieved with different forms of autogenous bone, including autogenous cortical bone particulate (ACBP). However, few histologic studies demonstrating the biologic potential and healing dynamics following the use of ACBP are currently available. This case report presents 2 patients in whom atrophic edentulous alveolar crests were submitted to a vertical/lateral ridge augmentation prior to implant placement. The technique was performed through the use of a titanium-reinforced expanded polytetrafluoroethylene (e-PTFE) membrane with an ACBP graft obtained from the retromolar region with a specially designed bone scraper. Bone biopsy specimens were harvested at 9 months after graft placement. Analysis of the reconstructed bone revealed bone with a lamellar quality characterized by a mature osteonic structure. Sparse particles of grafted bone were evident in direct contact with the regenerated bone. Marrow spaces showed a normal stromal component with limited grafted particles.
authors.affiliation: Research Center for the Study of Periodontal Diseases, University of Ferrara, Ferrara, Italy. leonardo.trombelli@unife.it
authors.forename: Leonardo
authors.initials: L
authors.lastname: Trombelli
authors.forename: Roberto
authors.initials: R
authors.lastname: Farina
authors.forename: Andrea
authors.initials: A
authors.lastname: Marzola
authors.forename: Angelo
authors.initials: A
authors.lastname: Itro
authors.forename: Giorgio
authors.initials: G
authors.lastname: Calura
mesh_terms: D020341:Absorbable Implants; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001857:Bone Matrix / Q000637:transplantation; D001861:Bone Regeneration / Q000502:physiology; D016025:Bone Transplantation / Q000379:methods*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D005260:Female; D006085:Graft Survival; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D007575:Jaw, Edentulous / Q000534:rehabilitation / Q000601:surgery; D008567:Membranes, Artificial; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D019651:Plastic Surgery Procedures / Q000379:methods; D013526:Surgical Mesh; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014025:Titanium; D016896:Treatment Outcome
chemical_list: D008567:Membranes, Artificial; D014025:Titanium