[Combined surgical and oncological management of colorectal liver metastases].
Isolated colorectal liver metastases should be referred for multispecialist management at a liver centre. Long-time survival is possible after resection and adjuvant therapy. If unresectable, newer chemotherapy with oxaliplatin, irinitecan, bevacizumab and cetuximab may result in a median survival > 20 months. Selected patients may be down-staged and resected with good long-time survival. Bilateral, multiple and large metastases can also be treated by complex combinations of portal vein embolization/ligature, staged resections and local (radiofrequency) ablation.
Bergenfeldt
Magnus
M
Herlev Hospital, Afdelingen for Kirurgisk Gastroenterologi, Herlev. maber@heh.regionh.dk
Jensen
Benny Vittrup
BV
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017115:Catheter Ablation; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000473:pathology; D003131:Combined Modality Therapy / Q000379:methods*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D020360:Neoadjuvant Therapy; D010166:Palliative Care; D011379:Prognosis