title: Diagnostic criteria for house dust mites sensitized allergic patients.
abstract: House dust mites (HDM) contain a large number of components that react with IgE in individuals with allergies and induced sensi-tization and allergic diseases. The work aimed to correlate between clinical manifestations of HDM allergic patients and skin prick test (SPT) grading, and to clarify some markers denoting allergic disorders caused by HDM exposure. Thirty allergic patients with positive SPT reaction to HDM were selected, grading of disease severity according to SPT and clinical presentations. The results revealed bronchial asthma (40%), atopic dermatitis (26.7%), rhinitis (20%) and conjuncttivitis (13.3%). Serum ELISA-IgE showed mean level of 398.41 +/- 84.73, 369.87 +/- 86.76, 332.16 +/- 65.57 and 300.25 +/- 79.39 IU/ml respecttively, with highly statistically significant difference between cases and controls (p < 0.001). Eosinophila showed highly significant difference between atopic dermatitis cases and controls (p < or = 0.001).
authors.affiliation: Department of Parasitology, Faculties of Medicine, Mansoura University, Mansoura.
authors.forename: Hala A
authors.initials: HA
authors.lastname: El-Nahas
authors.forename: Samar N
authors.initials: SN
authors.lastname: El-Beshbishi
authors.forename: Manar S
authors.initials: MS
authors.lastname: Azab
authors.forename: Tarek Kh
authors.initials: TKh
authors.lastname: Zaalouk
authors.forename: Hany M
authors.initials: HM
authors.lastname: Elsheikha
authors.forename: Abdel-Baset M
authors.initials: AB
authors.lastname: Saleh
authors.forename: Atef M
authors.initials: AM
authors.lastname: El-Shazly
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000276:immunology*; D000818:Animals; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis*; D008297:Male; D039981:Pyroglyphidae / Q000276:immunology*; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D012720:Severity of Illness Index
chemical_list: D000485:Allergens; D007073:Immunoglobulin E