Differences in areas of human frontal medial wall activated by left and right motor execution: dipole-tracing analysis of grand-averaged potentials incorporated with MNI three-layer head model.
Electroencephalography (EEG) is a non-invasive technique for monitoring electrical activity and has good time resolution. Combining these advantages of EEG with dipole-tracing analysis incorporating a realistic three-layer head model (scalp-skull-brain head model; SSB/DT) allows for the detection of dipoles in the millisecond range and investigation of the processing of cognitive function and movement execution. In this study, we constructed a scalp-skull-brain head model from Montreal Neurological Institute standard brain images and detected dipole localizations in the millisecond range from grand-averaged negative slope (NS) to motor potentials during a simple pinching movement. The left movement activated the presupplementary motor area (pre-SMA), rostral cingulate cortex and rostral premotor area, which are associated with cognitive functions and self-initiated decisions. These areas were associated with the early NS potential during left pinching movement preparation. The right movement activated the caudal cingulate cortex, pre-SMA and caudal premotor area, and these areas were activated just before the execution of movement.
Inoue
Manabu
M
Department of Physiology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Masaoka
Yuri
Y
Kawamura
Mitsuru
M
Okamoto
Yoshiwo
Y
Homma
Ikuo
I
D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D003071:Cognition / Q000502:physiology; D004569:Electroencephalography / Q000379:methods*; D007839:Functional Laterality / Q000502:physiology*; D006179:Gyrus Cinguli / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008959:Models, Neurological; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology; D011930:Reaction Time / Q000502:physiology