title: Tetrakis(trifluoromethanesulfonyl)propane: highly effective Brønsted acid catalyst for vinylogous Mukaiyama-Michael reaction of alpha,beta-enones with silyloxyfurans.
abstract: 1,1,3,3-Tetrakis(trifluoromethanesulfonyl)propane was found as an excellent Brønsted acid catalyst for the Mukaiyama-Michael reaction of alpha,beta-enones with 2-silyloxyfurans; using beta,beta-disubstituted enones as a Michael acceptor, an excellent yield construction of quaternary carbon centers could be achieved; in addition, very low catalyst loading of Brønsted acid was used in a range from 0.05 to 1.0 mol%.
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1423-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
authors.forename: Arata
authors.initials: A
authors.lastname: Takahashi
authors.forename: Hikaru
authors.initials: H
authors.lastname: Yanai
authors.forename: Takeo
authors.initials: T
authors.lastname: Taguchi
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D011407:Propane / Q000031:analogs & derivatives* / Q000737:chemistry; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D005663:Furans; D007659:Ketones; D008698:Mesylates; D014753:Vinyl Compounds; C012077:trifluoromethanesulfonic acid; D011407:Propane