[Important contribution and necessity of stem cells scaffolds for regenerative medicine and the therapeutic applications].
For successful regeneration therapy of tissues and organs, it is important and indispensable to develop the technology and methodology of tissue engineering with biomaterials for molecular design and creation of a local environment which enables stem cells to enhance the proliferation and differentiation, inducing cell-based tissue regeneration. Various scaffolds of biomaterials have been investigated to demonstrate the feasibility in the basic researches of stem cell biology and the applications of their results to regenerative therapy. This paper introduces several examples of regenerative medical therapy based on tissue engineering technologies to emphasize the scientifically and clinically significant contribution of cell scaffolds not only to the regenerative medicine of basic stem cell researches, but also to their therapeutic applications of regenerative medicine.
Tabata
Yasuhiko
Y
Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University.
D000818:Animals; D001672:Biocompatible Materials; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D012038:Regeneration; D044968:Regenerative Medicine / Q000379:methods; D013234:Stem Cells / Q000166:cytology; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
D001672:Biocompatible Materials