[Links between osteoporosis and atherosclerosis; beyond insulin resistance].
Both osteoporosis and atherosclerosis progress with aging. For the progression of atherosclerosis, insulin resistance, often resulted from obesity, is one of the established contributing factors. However, obesity, hence insulin resistance, act protectively for bone. Recently, chronic inflammation, associated with oxidative stress, has been proposed to be one of the missing links between atherosclerosis and osteoporosis.
Okazaki
Ryo
R
Teikyo University Chiba Medical Center, Third Department of Medicine.
D017667:Adipocytes / Q000378:metabolism; D050197:Atherosclerosis / Q000209:etiology*; D015519:Bone Density; D002097:C-Reactive Protein; D002908:Chronic Disease; D016207:Cytokines / Q000378:metabolism / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000150:complications; D007333:Insulin Resistance / Q000502:physiology; D009765:Obesity / Q000150:complications; D010024:Osteoporosis / Q000209:etiology*; D018384:Oxidative Stress / Q000502:physiology; D012307:Risk Factors
D016207:Cytokines; D002097:C-Reactive Protein