title: Epidemiological shift, seasonal variation and antimicrobial susceptibility patterns among enteric fever pathogens in South India.
abstract: Between January 2005 and December 2006, a higher incidence of paratyphoid fever (53.8%) compared to typhoid fever (44.9%) has been observed at a tertiary hospital in South India. A definite seasonal pattern of incidence is seen in paratyphoid fever (peak incidence during October-December, i.e., post monsoon period) but not in typhoid fever. Decreased fluoroquinolone susceptibility is much higher in S. Paratyphi A (98.8%) as compared to S. Typhi (46.5%). These findings are of importance in therapeutic decision making, development of vaccination strategies and implementing public health measures for disease control.
authors.affiliation: Department of Microbiology, Kasturba Medical College, Mangalore 575001, Karnataka, India. k.vidyalakshmi@lycos.com
authors.forename: K
authors.initials: K
authors.lastname: Vidyalakshmi
authors.forename: R
authors.initials: R
authors.lastname: Yashavanth
authors.forename: M
authors.initials: M
authors.lastname: Chakrapani
authors.forename: B
authors.initials: B
authors.lastname: Shrikala
authors.forename: B
authors.initials: B
authors.lastname: Bharathi
authors.forename: U
authors.initials: U
authors.lastname: Suchitra
authors.forename: B
authors.initials: B
authors.lastname: Dhanashree
authors.forename: R M S
authors.initials: RM
authors.lastname: Dominic
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001769:Blood / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003470:Culture Media; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012482:Salmonella paratyphi A / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D012485:Salmonella typhi / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D012621:Seasons; D014435:Typhoid Fever / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media