title: The peptide-catalyzed Maillard reaction: characterization of 13C reductones.
abstract: The reaction pathways of amino acids and reducing sugars are now fully understood. The focus in the last few years, however, has turned to the reaction of peptides and proteins with reducing sugars. We have investigated the reaction of gamma-aminobutanoic acid, the heptapeptide Nalpha-Acetyl-Lys-Lys-beta-Ala-Lys-beta-Ala-Lys-Gly, and the model protein beta-casein in Maillard reactions with 1-13C arabinose. Characterization of 13C-labeled acetic acid and norfuraneol by gas chromatography-mass spectrometry and nuclear magnetic resonance revealed new formation pathways. The results demonstrate significant differences in the labeling pattern of the products depending on the amine used, indicating different formation pathways of acetic acid and norfuraneol.
authors.affiliation: Technische Universität Berlin, Molecular Analysis, Berlin, Germany. leif-a.garbe@tu-berlin.de
authors.forename: Leif Alexander
authors.initials: LA
authors.lastname: Garbe
authors.forename: Alexander
authors.initials: A
authors.lastname: Würtz
authors.forename: Christian T
authors.initials: CT
authors.lastname: Piechotta
authors.forename: Roland
authors.initials: R
authors.lastname: Tressl
mesh_terms: D000588:Amines / Q000737:chemistry; D002247:Carbon Isotopes; D015416:Maillard Reaction; D013058:Mass Spectrometry; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry; D009930:Organic Chemicals / Q000737:chemistry; D010084:Oxidation-Reduction; D010455:Peptides / Q000737:chemistry*; D005680:gamma-Aminobutyric Acid / Q000737:chemistry
chemical_list: D000588:Amines; D002247:Carbon Isotopes; D009842:Oligopeptides; D009930:Organic Chemicals; D010455:Peptides; D005680:gamma-Aminobutyric Acid