title: Morphological changes in the ovaries during modeling of functional cysts of hormonal genesis.
abstract: Morphological study of ovarian follicular cysts induced by chorionic gonadotropin (300 U) and insulin (Protafane HM; 2.5 U) in adult rats showed that superovulatory dose of chorionic gonadotropin and moderate hyperinsulinemia induced the development of ovarian cysts on days 3-5 in 100% cases. Dynamic study of ovarian morphology showed that changes were reversible and the cysts regressed within 60 days, which confirmed their functional nature.
authors.affiliation: Department of Histology, Embryology, and Cytology, Siberian State Medical University, Tomsk.
authors.forename: S V
authors.initials: SV
authors.lastname: Logvinov
authors.forename: O A
authors.initials: OA
authors.lastname: Tikhonovskaya
authors.forename: I A
authors.initials: IA
authors.lastname: Petrov
authors.forename: M S
authors.initials: MS
authors.lastname: Petrova
authors.forename: Y V
authors.initials: YV
authors.lastname: Petrina
authors.forename: A O
authors.initials: AO
authors.lastname: Okorokov
mesh_terms: D000818:Animals; D006063:Chorionic Gonadotropin / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D007328:Insulin / Q000378:metabolism / Q000494:pharmacology; D010048:Ovarian Cysts / Q000378:metabolism / Q000473:pathology; D010053:Ovary / Q000166:cytology / Q000187:drug effects; D051381:Rats
chemical_list: D006063:Chorionic Gonadotropin; D007328:Insulin