title: Structure revision of circumdatins A and B, benzodiazepine alkaloids produced by marine fungus Aspergillus ostianus, by X-ray crystallography.
abstract: The structures of circumdatins A and B, pentacyclic alkaloids produced by Aspergillus ostianus, were revised from the previously reported betaine structures to unique oxepin ones by X-ray crystallography. The co-occurring known alkaloids, circumdatins D, E, and H, and a new compound reported here, circumdatin J, have a common framework.
authors.affiliation: Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8505, Japan and Tohoku Pharmaceutical University, Aoba-ku, Sendai, Japan
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Ookura
authors.forename: Keijiro
authors.initials: K
authors.lastname: Kito
authors.forename: Takashi
authors.initials: T
authors.lastname: Ooi
authors.forename: Michio
authors.initials: M
authors.lastname: Namikoshi
authors.forename: Takenori
authors.initials: T
authors.lastname: Kusumi
mesh_terms: D001230:Aspergillus / Q000378:metabolism*; D001570:Benzodiazepinones / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008386:Marine Biology; D013058:Mass Spectrometry; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D001570:Benzodiazepinones; C530782:circumdatin A; C530783:circumdatin B