Effects of oil heated with gluten on weight-loss dieting. II.
We previously proposed that oil heated with gluten was suitable for use as a safe oil for weight-loss dieting. In the present paper, the properties of the oil were improved, and the weight-loss effect was compared with that of heated oil. Fresh oil was heated for 10 h at 180 degrees C with or without gluten and filtered using filter paper. A powdered diet (AIN93G; no fat) was mixed with 7 wt% of fresh oil (control) or filtrates of the heated oils described above, and the mixture was fed to male Wistar rats for 12 weeks. The gluten and heated oil groups showed no gross symptoms attributable to the experimental oils but had a slowed body weight increase; a significant difference was found in weight on and after 21 weeks of age as compared to rats consuming the control diet, and fecal excretion was increased as compared to the control group. Serum levels of triacylglycerol, phospholipids, cholesterol, and glucose of the gluten and heated oil groups were significantly lower than those of the control group. High aspartate aminotransferase (AST) levels occurred more frequently in the heated oil group than the gluten group. The number of rats with dark red patches on the surface of the liver, which are indicative of liver damage, was higher in the heated oil group. In conclusion, the weight-reducing effect of the oil heated with gluten was confirmed and improved by removing traces of heated gluten from the oil.
Totani
Nagao
N
Faculty of Nutrition, Kobe-Gakuin University, Kobe, Japan. totani@nutr.kobegakuin.ac.jp
Burenjargal
Munkhjargal
M
Tateishi
Sayuri
S
Yawata
Miho
M
D000596:Amino Acids / Q000737:chemistry*; D000821:Animal Feed; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D004038:Diet, Reducing; D005983:Glutens / Q000737:chemistry*; D008099:Liver / Q000473:pathology; D008297:Male; D009821:Oils / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D013696:Temperature; D014280:Triglycerides / Q000097:blood
D000596:Amino Acids; D001786:Blood Glucose; D009821:Oils; D014280:Triglycerides; D005983:Glutens; D002784:Cholesterol; D001219:Aspartate Aminotransferases