title: Ingesting 500 ml of polyethylene glycol solution during capsule endoscopy improves the image quality and completion rate to the cecum.
abstract: The benefits of bowel preparation prior to capsule endoscopy (CE) are controversial. The aim of this study was to examine whether ingesting a small amount of polyethylene glycol (PEG) during, not before, the CE procedure improves the image quality and the cecal completion rate. A prospective single-blind controlled study was conducted including 59 patients. The initial 32 patients (group A) received no preparation, and the subsequent 27 patients (group B) ingested 500 ml of PEG starting 30 min after swallowing the capsule. The capsule reached the cecum in 65.6% of the patients in group A and 88.9% of the patients in group B (P = 0.038). The use of PEG during CE examination significantly improved the image quality, and this effect was more pronounced in the distal ileum. Ingesting a small amount of PEG during CE examination significantly improves both the CE image quality and the cecal completion rate.
authors.affiliation: Gastroenterology Division, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. t066011b@yokohama-cu.ac.jp
authors.forename: Hiroki
authors.initials: H
authors.lastname: Endo
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kondo
authors.forename: Masahiko
authors.initials: M
authors.lastname: Inamori
authors.forename: Tomohiko R
authors.initials: TR
authors.lastname: Ohya
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yanagawa
authors.forename: Masako
authors.initials: M
authors.lastname: Asayama
authors.forename: Kantaro
authors.initials: K
authors.lastname: Hisatomi
authors.forename: Takuma
authors.initials: T
authors.lastname: Teratani
authors.forename: Masato
authors.initials: M
authors.lastname: Yoneda
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakajima
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Matsuhashi
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053704:Capsule Endoscopy / Q000379:methods*; D002432:Cecum / Q000187:drug effects / Q000502:physiology; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007082:Ileum / Q000187:drug effects / Q000502:physiology; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000008:administration & dosage* / Q000494:pharmacology; D011446:Prospective Studies; D016037:Single-Blind Method; D013501:Surface-Active Agents / Q000008:administration & dosage* / Q000494:pharmacology; D055815:Young Adult
chemical_list: D013501:Surface-Active Agents; D011092:Polyethylene Glycols