[Clinical and microbiological study of compound of light yellow Sophora root collutory on treatment of oral lichen planus].
OBJECTIVE
To evaluate the effect of compound light yellow Sophora root collutory on oral erosive lichen planus and analyze the salivary microbial contents and proportion.


METHODS
30 patients with oral erosive lichen planus were chosen and treated with compound light yellow Sophora root collutory. Pain index and clinical symptoms were observed, the changes of quantity and proportion of salivary bacteria were investigated before and after taking drugs. SAS6.12 software package was used for statistical analysis.


RESULTS
The extravasate and congest of the erosive mucous membrane were relieved. The pain caused by erosion were significantly relieved after taking the drugs. The quantity of oral Staphylococcus was significantly decreased after taking the drugs.


CONCLUSIONS
Oral Staphylococcus can be inhibited by light yellow Sophora root collutory. The use of compound light yellow Sophora root collutory is one of the safe and effective local therapies on oral lichen planus.
Wu
Lan
L
Department of Oral Mucosal Diseases, College of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhou
Zeng-Tong
ZT
Wu
Fei-Hua
FH
Li
Ming-Yu
MY
D006801:Humans; D017676:Lichen Planus, Oral / Q000188:drug therapy* / Q000382:microbiology; D010936:Plant Extracts / Q000627:therapeutic use*; D029909:Sophora; D013210:Staphylococcus / Q000302:isolation & purification
D010936:Plant Extracts