Bonding of macromolecular hydrogels using perturbants.
This work describes a method to bond patterned macromolecular gels into monolithic structures using perturbants. Bonding strengths for a variety of solutes follow a Hofmeister ordering; this result and optical measurements indicate that bonding occurs by reversible perturbation of contacting gels. The resulting microfluidic gels are mechanically robust and can serve as scaffolds for cell culture.
Price
Gavrielle M
GM
Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA.
Chu
Kengyeh K
KK
Truslow
James G
JG
Tang-Schomer
Min D
MD
Golden
Andrew P
AP
Mertz
Jerome
J
Tien
Joe
J
D018929:Cell Culture Techniques / Q000379:methods; D042783:Endothelial Cells / Q000166:cytology; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry*; D008970:Molecular Weight; D012996:Solutions
D020100:Hydrogels; D046911:Macromolecular Substances; D012996:Solutions