Flow-injection chemiluminescence determination of ofloxacin using the Ru(bpy)2(CIP)2+-Ce(IV) system and its application.
This paper reports a flow-injection chemiluminescence method for the determination of ofloxacin (OFLX) using the Ru(bpy)2(CIP)2+-Ce(IV) system. Under the optimum conditions, the relative CL intensity was proportional to the concentration of OFLX in the range 3.0 x 10(-8)-1.0 x 10(-5) mol/L and the detection limit was 4.2 x 10(-9) mol/L. The proposed method has been successfully applied to the determination of ofloxacin in pharmaceuticals and human urine. The chemiluminescence mechanism of the system is also discussed.
Chen
Li
L
College of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China.
Wang
Xiaoli
X
Zhao
Huichun
H
Wang
Kezhi
K
Jin
Linpei
L
D000900:Anti-Bacterial Agents / Q000032:analysis; D002563:Cerium; D017022:Flow Injection Analysis; D008163:Luminescent Measurements / Q000295:instrumentation / Q000379:methods*; D008722:Methods; D015242:Ofloxacin / Q000032:analysis*; D009942:Organometallic Compounds; D012428:Ruthenium
D000900:Anti-Bacterial Agents; D009942:Organometallic Compounds; D002563:Cerium; D012428:Ruthenium; D015242:Ofloxacin