title: Preparation and characterization of bioglass/polyvinyl alcohol composite hydrogel.
abstract: In order to form firm active fixation with the adjacent bone, a new kind of bioactive composite hydrogel was prepared with polyvinyl alcohol (PVA) and bioglass (BG) through ultrasonic dispersion, heat-high-pressure and freeze/thawed technique. A digital speckle correlation method (DSCM) was utilized to characterize the mechanical properties of the series of BG/PVA composites. Results showed that at different load pressures, the composite hydrogel displayed different displacement and deformation in the V field. Results also showed that an increase of PVA percentage (15-30 wt%) or of bioglass percentage (2-10 wt%) in composite hydrogel could lead to an increase in the elastic compression modulus. Scanning electron microscope results indicated that bioglass was uniformly dispersed in the BG/PVA composite hydrogel. The BG/PVA composite hydrogel shows a promising prospect as a new bionic cartilage implantation material.
authors.affiliation: College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, People's Republic of China.
authors.forename: Hong
authors.initials: H
authors.lastname: Xu
authors.forename: Yingjun
authors.initials: Y
authors.lastname: Wang
authors.forename: Yudong
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Chen
authors.forename: Li
authors.initials: L
authors.lastname: Ren
authors.forename: Gang
authors.initials: G
authors.lastname: Wu
authors.forename: Xiaoshan
authors.initials: X
authors.lastname: Huang
mesh_terms: D018786:Bone Substitutes / Q000737:chemistry*; D002516:Ceramics / Q000737:chemistry*; D019245:Compressive Strength; D004548:Elasticity; D005898:Glass; D020100:Hydrogels / Q000737:chemistry*; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D011142:Polyvinyl Alcohol / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D018786:Bone Substitutes; D020100:Hydrogels; C425330:bioactive glass 45S5; D011142:Polyvinyl Alcohol