Reversible posterior encephalopathy syndrome in systemic lupus erythematosus and lupus nephritis.
Reversible posterior encephalopathy syndrome (RPES) is a clinical entity characterized with headache, nausea, vomiting, seizures, consciousness disturbance, and frequently visual disorders associated with neuroradiological findings, predominantly white matter abnormalities of the parieto-occipital lobes. The central nervous system manifestations of systemic lupus erythematosus (SLE) are highly diverse. However, SLE-associated RPES has been seldom reported. Here, we report a case with RPES in SLE and lupus nephritis with exclusive involvement of parietal and occipital cortices. A systematic review of the literature on the pathogenesis and treatment of SLE-associated RPES is included.
Zhang
Yan-Xing
YX
Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China.
Liu
Jian-Ren
JR
Ding
Mei-Ping
MP
Huang
Jian
J
Zhang
Min
M
Jansen
Olav
O
Deuschl
Günther
G
Eschenfelder
Christoph Cyrill
CC
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D017315:Cilazapril / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008181:Lupus Nephritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D054038:Posterior Leukoencephalopathy Syndrome / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology
D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D017315:Cilazapril