title: Convenient Synthesis of a Library of Discrete Hydroxamic Acids Using the Hydroxythiophenol (Marshall) Resin.
abstract: Several resins have reportedly been used to synthesize hydroxamic acids except for the hydroxythiophenol (Marshall) resin. Herein we report the use of the Marshall resin to synthesize hydroxamic acids from carboxylic acids and its application to convert a library of fourteen discrete aliphatic and aromatic carboxylic acids including N-protected amino acids to their corresponding hydroxamic acids in good yields.
authors.affiliation: Computer-Aided Molecular Design Laboratory, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Jinil
authors.initials: J
authors.lastname: Choi
authors.forename: Jewn Giew
authors.initials: JG
authors.lastname: Park
authors.forename: Yuan-Ping
authors.initials: YP
authors.lastname: Pang