title: A primer on pharmacokinetics.
abstract: Pharmacokinetics describes the time course of the drug concentration following administration of a specific dosage regimen. An understanding of pharmacokinetic principles will assist the clinician in designing an individualized dosage regimen that achieves the desired drug concentration.
authors.affiliation: UCSF Medical Center, University of California San Francisco, San Francisco, CA, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Quan
mesh_terms: D000284:Administration, Oral; D001682:Biological Availability; D002302:Cardiac Output; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004347:Drug Interactions; D016903:Drug Monitoring / Q000379:methods*; D006207:Half-Life; D006801:Humans; D007668:Kidney / Q000502:physiology; D008099:Liver / Q000502:physiology; D008657:Metabolic Clearance Rate; D010599:Pharmacokinetics; D006435:Renal Dialysis; D014018:Tissue Distribution