Epidemiological shift, seasonal variation and antimicrobial susceptibility patterns among enteric fever pathogens in South India.
Between January 2005 and December 2006, a higher incidence of paratyphoid fever (53.8%) compared to typhoid fever (44.9%) has been observed at a tertiary hospital in South India. A definite seasonal pattern of incidence is seen in paratyphoid fever (peak incidence during October-December, i.e., post monsoon period) but not in typhoid fever. Decreased fluoroquinolone susceptibility is much higher in S. Paratyphi A (98.8%) as compared to S. Typhi (46.5%). These findings are of importance in therapeutic decision making, development of vaccination strategies and implementing public health measures for disease control.
Vidyalakshmi
K
K
Department of Microbiology, Kasturba Medical College, Mangalore 575001, Karnataka, India. k.vidyalakshmi@lycos.com
Yashavanth
R
R
Chakrapani
M
M
Shrikala
B
B
Bharathi
B
B
Suchitra
U
U
Dhanashree
B
B
Dominic
R M S
RM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001769:Blood / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003470:Culture Media; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012482:Salmonella paratyphi A / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D012485:Salmonella typhi / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D012621:Seasons; D014435:Typhoid Fever / Q000453:epidemiology* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D003470:Culture Media