title: SWNT-DNA and SWNT-polyC hybrids: AFM study and computer modeling.
abstract: Hybrids of carbon single-walled nanotubes (SWNT) with fragmented single or double-stranded DNA (fss- or fds-DNA) or polyC were studied by Atom Force Microscopy (AFM) and computer modeling. It was found that fragments of the polymer wrap in several layers around the nanotube, forming a strand-like spindle. In contrast to the fss-DNA, the fds-DNA also forms compact structures near the tube surface due to the formation of self-assembly structures consisting of a few DNA fragments. The hybrids of SWNT with wrapped single-, double- or triple strands of the biopolymer were simulated, and it was shown that such structures are stable. To explain the reason of multi-layer polymeric coating of the nanotube surface, the energy of the intermolecular interactions between different components of polyC was calculated at the MP2/6-31++G** level as well as the interaction energy in the SWNT-cytosine complex.
authors.affiliation: B. I. Verkin Institute for Low Temperature Physics and Engineering, National Academy of Science of Ukraine, Kharkov 61103, Ukraine.
authors.forename: M V
authors.initials: MV
authors.lastname: Karachevtsev
authors.forename: O S
authors.initials: OS
authors.lastname: Lytvyn
authors.forename: S G
authors.initials: SG
authors.lastname: Stepanian
authors.forename: V S
authors.initials: VS
authors.lastname: Leontiev
authors.forename: L
authors.initials: L
authors.lastname: Adamowicz
authors.forename: V A
authors.initials: VA
authors.lastname: Karachevtsev
mesh_terms: D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D018625:Microscopy, Atomic Force / Q000379:methods; D036103:Nanotechnology; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D011066:Poly C / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D004277:DNA, Single-Stranded; D037742:Nanotubes, Carbon; D011066:Poly C; D004247:DNA