title: [Pathologic anatomy of pneumonia caused by Legionella: on the materials of outbreak in town Verkhnyaya Pyshma].
abstract: Data on postmortem examination of five patients deceased during Legionnaires' outbreak in town Verkhnyaya Pyshma are presented in the article. Feature of course of the disease was severe affection of the lungs with development of toxic shock. Pathomorphological picture in lungs was characterized by polymorphism, presence of shock reaction and ventilator-associated pneumonia (atelectases, distelectases, tracheobronchitis). In autopsy material from four fatal cases Legionella pneumophila serogroup 1 was detected. Causative agent of pneumonia was not determined in one fatal case although comparison of clinical and morphological characteristics of this case with other four cases as well as detection of Gram-negative bacillus in alveolar macrophages allowed to consider this case of pneumonia as caused by Legionella. In studied fatal cases postmortem diagnoses were ascertained in which main disease was bilateral pneumonia caused by Legionella pneumophila serogroup 1 complicated by toxic shock.
authors.forename: E S
authors.initials: ES
authors.lastname: Belikov
authors.forename: A G
authors.initials: AG
authors.lastname: Trifonova
authors.forename: L M
authors.initials: LM
authors.lastname: Kotsurak
authors.forename: I E
authors.initials: IE
authors.lastname: Belikov
authors.forename: D O
authors.initials: DO
authors.lastname: Mikhaĭlova
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001344:Autopsy; D001991:Bronchitis / Q000473:pathology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000473:pathology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D016952:Legionella pneumophila / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000453:epidemiology / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D001261:Pulmonary Atelectasis / Q000473:pathology; D012426:Russia / Q000453:epidemiology; D012769:Shock / Q000473:pathology; D014136:Tracheitis / Q000473:pathology