High-resolution genotyping of Aspergillus fumigatus isolates recovered from chronically colonised patients with cystic fibrosis.
A series of 256 Aspergillus fumigatus isolates, recovered from eight patients with cystic fibrosis (CF), were genotyped using microsatellite-based typing. Only a limited number of genotypes were shared between patients and co-colonisation with multiple strains was indicated for all patients. Additionally, some genotypes were isolated recurrently, indicating that they are capable of prolonged colonisation.
Vanhee
L M E
LM
Laboratory for Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.
Symoens
F
F
Bouchara
J-P
JP
Nelis
H J
HJ
Coenye
T
T
D001228:Aspergillosis / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000145:classification* / Q000235:genetics*; D016000:Cluster Analysis; D003550:Cystic Fibrosis / Q000150:complications*; D016172:DNA Fingerprinting; D004271:DNA, Fungal / Q000235:genetics; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats; D017720:Molecular Epidemiology; D016533:Mycological Typing Techniques
D004271:DNA, Fungal