Enhancing effect of cerebral blood volume by mild exercise in healthy young men: a near-infrared spectroscopy study.
A mechanism by which exercise improves brain function may be attributed to increase in cerebral blood volume (CBV) with physical activity. However, the exact exercise intensity that influences CBV is still uncertain. To clarify this issue, 10 healthy young male participants were asked to perform a graded cycling exercise to the point of exhaustion while their prefrontal cortex CBVs are being monitored using near-infrared spectroscopy. Overall responsive cerebral oxygenation showed a non-linear pattern with three distinct phases. The CBV-threshold (CBVT), an event where rapid oxygenation takes place, occurred at approximately 42% of the V O2max. The CBVT preceded the lactate threshold (LT), which was at approximately 55% of the V O2max. The V O2max was not predictive of the CBVT in among the subjects. Our results indicate that oxygenation of the prefrontal cortex increases during graded cycling even at exercise intensities below the LT, suggesting the potential role of mild exercise in enhancing CBV.
Timinkul
Akkaranee
A
Laboratory of Exercise Biochemistry, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba 305-8574, Japan.
Kato
Morimasa
M
Omori
Takenori
T
Deocaris
Custer C
CC
Ito
Akira
A
Kizuka
Tomohiro
T
Sakairi
Yosuke
Y
Nishijima
Takeshi
T
Asada
Takashi
T
Soya
Hideaki
H
D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology; D001810:Blood Volume / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D010108:Oxyhemoglobins / Q000378:metabolism; D019265:Spectroscopy, Near-Infrared
D010108:Oxyhemoglobins; D019344:Lactic Acid