title: Flow-area relationship in internal carotid and vertebral arteries.
abstract: Subject-specific computational and experimental models of hemodynamics in cerebral aneurysms require the specification of physiologic flow conditions. Because patient-specific flow data are not always available, researchers have used 'typical' or population average flow rates and waveforms. However, in order to be able to compare the magnitude of hemodynamic variables between different aneurysms or groups of aneurysms (e.g. ruptured versus unruptured) it is necessary to scale the flow rates to the area of the inflow artery. In this work, a relationship between flow rates and vessel areas is derived from phase-contrast magnetic resonance measurements in the internal carotid arteries and vertebral arteries of normal subjects.
authors.affiliation: Center for Computational Fluid Dynamics, George Mason University, Fairfax, VA 22030, USA. jcebral@gmu.edu
authors.forename: J R
authors.initials: JR
authors.lastname: Cebral
authors.forename: M A
authors.initials: MA
authors.lastname: Castro
authors.forename: C M
authors.initials: CM
authors.lastname: Putman
authors.forename: N
authors.initials: N
authors.lastname: Alperin
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D002343:Carotid Artery, Internal / Q000033:anatomy & histology* / Q000502:physiology*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008955:Models, Cardiovascular; D012016:Reference Values; D013223:Statistics as Topic; D014711:Vertebral Artery / Q000033:anatomy & histology* / Q000502:physiology*