title: (Iso)-quinoline alkaloids from fungal fruiting bodies of Cortinarius subtortus.
abstract: Chemical analysis of the fruiting bodies of the agaricoid fungus Cortinarius subtortus yielded three new natural products, two quinoline and one isocarbostyryl alkaloid. The structures of compounds 1- 3 were determined by analysis of NMR and MS data. Compound 1 exhibited inhibitory effects against the phytopathogenic fungus Colletotrichum coccodes. All three compounds displayed moderate antioxidant activity in a DPPH free radical scavenging bioassay.
authors.affiliation: Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle/Saale, Germany.
authors.forename: Axel
authors.initials: A
authors.lastname: Teichert
authors.forename: Jürgen
authors.initials: J
authors.lastname: Schmidt
authors.forename: Andrea
authors.initials: A
authors.lastname: Porzel
authors.forename: Norbert
authors.initials: N
authors.lastname: Arnold
authors.forename: Ludger
authors.initials: L
authors.lastname: Wessjohann
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds; D020231:Colletotrichum / Q000187:drug effects* / Q000254:growth & development; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D005858:Germany; D007546:Isoquinolines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000935:Antifungal Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007546:Isoquinolines; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl