title: Kits and their unique role in molecular biology: a brief retrospective.
abstract: Since their initial development nearly 20 years ago, molecular biology kits have evolved from simple protocols and reagents for cloning of DNA to the more recent complex reagent sets that enable whole genomic sequencing. Initially met with resistance by some who felt that using them deprived researchers of the basic knowledge of how to create reagents, molecular biology kits have taken on an important role in the biological sciences. In this article we describe kit development, why kits have succeeded in molecular biology, and how they have paved the way for the more recent widespread use of core facilities.
authors.affiliation: Affomix Corporation, New Haven, CT 06511, USA. mweiner@affomix.com
authors.forename: Michael
authors.initials: M
authors.lastname: Weiner
authors.forename: Barton
authors.initials: B
authors.lastname: Slatko
mesh_terms: D008967:Molecular Biology / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D015336:Molecular Probe Techniques / Q000295:instrumentation* / Q000639:trends*; D011933:Reagent Kits, Diagnostic / Q000639:trends*; D017422:Sequence Analysis, DNA / Q000295:instrumentation* / Q000379:methods* / Q000639:trends
chemical_list: D011933:Reagent Kits, Diagnostic