title: Residues of deoxynivalenol (DON) in pig tissue after feeding mash or pellet diets containing low concentrations.
abstract: Residues of deoxynivalenol (DON) and its metabolite de-epoxy-DON (DOM) were analyzed in specimens of pigs fed diets containing 0, 25, and 50% contaminated wheat (2.5 mg DON/kg) fed as mash or pellets over the final growing period of 11 wk. Median DON concentrations decreased from bile > kidney > serum > liver = muscle, while DOM was only detected in bile and kidney. Maximum carry over rates were 0.0319 for kidney, 0.0064 for liver, and 0.0043 for muscle, demonstrating that the contribution of animal derived food to the consumers' exposure is very low. The high interindividual variation of DON concentrations in all analyzed specimen of pigs fed diets containing similar concentrations of DON does not allow a diagnostic differentiation of animals fed diets containing DON concentrations of approximately 61% of the guidance level of 0.9 mg DON/kg, and those fed diets containing 137% of this concentration. The different feed forms did not affect residue concentrations in any of the investigated specimens.
authors.affiliation: Institute of Animal Nutrition, Friedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Braunschweig, Germany. susanne.doell@fli.bund.de
authors.forename: Susanne
authors.initials: S
authors.lastname: Döll
authors.forename: Sven
authors.initials: S
authors.lastname: Dänicke
authors.forename: Hana
authors.initials: H
authors.lastname: Valenta
mesh_terms: D000818:Animals; D004032:Diet; D004350:Drug Residues / Q000032:analysis; D005506:Food Contamination / Q000032:analysis*; D007668:Kidney / Q000737:chemistry; D008099:Liver / Q000737:chemistry; D008297:Male; D008460:Meat / Q000032:analysis*; D009132:Muscles / Q000737:chemistry; D013552:Swine; D014255:Trichothecenes / Q000008:administration & dosage / Q000032:analysis*; D014908:Triticum
chemical_list: D014255:Trichothecenes; C007262:deoxynivalenol