Therapeutics and immune-mediated skin disease.
Our increased understanding of the mechanisms of immune-mediated skin disease has led to the growth of therapeutic options for these diseases. Treatment options impact the various levels of the immune response, including the activation and effector function of immune cells. In this review, we give a broad outline of the steps in the immune process that can be altered by immunomodulatory therapy as well as a working model for the potential areas of intervention for new treatments.
Gordon
Kenneth B
KB
Division of Dermatology, Evanston Northwestern Healthcare, Evanston, IL, USA. kgordon@enh.org
Satoskar
Rebecca
R
D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D012871:Skin Diseases / Q000276:immunology* / Q000473:pathology / Q000628:therapy*