title: Surgical treatment using an allograft dermal matrix for nasal septal perforation.
abstract: OBJECTIVE
  Numerous methods have been utilized to repair nasal septal perforation with varying degrees of success; however, no consensus has been reached on nasoseptal perforation repair. Here, the authors describe a surgical method based on human dermal allograft (Surederm, Hans Biomed Corp. Korea) for the repair of nasal septal perforations.
  
  
  METHODS
  Eleven patients with a nasal septal perforation were included in this study. The causes of these septal perforations included previous nasal surgery, trauma, foreign body (button battery), and idiopathy. There were several sites of perforation: 9 in the central area, 1 in the posterior-central area, and 1 in the anterior area. An interpositional graft incorporating Surederm was positioned between bilateral mucoperichondrial flaps using an intranasal approach. A silastic sheet was then left in the nasal septum bilaterally until complete healing had occurred through new nasal mucosa, which took a mean duration of 6 weeks.
  
  
  RESULTS
  Outcomes in ten of the eleven patients were successful, with complete septal perforation closure. The remaining perforation, which was caused by a button battery, closed incompletely; however, its initial size of 2 cm was reduced to 5 mm.
  
  
  CONCLUSIONS
  The described technique has a high success rate and can be performed under local anesthesia without external scarring. In the absence of donor site morbidity, this technique can also be utilized to repair posterior or multiple septal perforations without difficulty.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyoung-dong, Jongro-gu, Seoul 110-746, Korea.
authors.forename: Kyung Chul
authors.initials: KC
authors.lastname: Lee
authors.forename: No Hee
authors.initials: NH
authors.lastname: Lee
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Ban
authors.forename: Sung Min
authors.initials: SM
authors.lastname: Jin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D020405:Dermis / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000473:pathology / Q000601:surgery*; D009668:Nose Diseases / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods; D014184:Transplantation, Homologous; D016896:Treatment Outcome