title: A cyclotrimerization route to cannabinoids.
abstract: Three members of the cannabinoid class, cannabinol, cannabinol methyl ether, and cannabinodiol, were synthesized using a microwave-mediated [2 + 2 + 2] cyclotrimerization reaction as the key step. This approach provides a high level of synthetic flexibility allowing for the facile synthesis of cannabinoid analogues.
authors.affiliation: North Carolina State University, Department of Chemistry, Raleigh, North Carolina 27695-8204, USA.
authors.forename: Jesse A
authors.initials: JA
authors.lastname: Teske
authors.forename: Alexander
authors.initials: A
authors.lastname: Deiters
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002186:Cannabinoids / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D009570:Nitriles / Q000737:chemistry
chemical_list: D000480:Alkynes; D002186:Cannabinoids; D009570:Nitriles