title: How complex is GTPase signaling in trypanosomes?
abstract: Many signaling pathways in higher eukaryotes use Ras-like small GTPases. Here, we ask how complex are these small GTPase signaling pathways in trypanosomes? We seek to address this issue by comparisons with the representation of both the GTPase molecules and their accessory factors in several genomes.
authors.affiliation: The Molteno Building, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK. mcf34@cam.ac.uk
authors.forename: Mark C
authors.initials: MC
authors.lastname: Field
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: O'Reilly
mesh_terms: D000818:Animals; D020558:GTP Phosphohydrolases / Q000235:genetics* / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic; D017125:Genes, Protozoan; D018503:Genome, Protozoan; D015398:Signal Transduction; D014345:Trypanosoma / Q000201:enzymology*
chemical_list: D020558:GTP Phosphohydrolases