title: Do current outcomes justify more liberal use of revascularization for vasculogenic claudication? A single center experience of 1,000 consecutively treated limbs.
abstract: BACKGROUND
  The purpose of this study was to reconsider current recommended treatment guidelines for vasculogenic claudication by examining the contemporary results of surgical intervention.
  
  
  METHODS
  We performed a retrospective review of 1,000 consecutive limbs in 669 patients treated for medically refractory vasculogenic claudication and prospectively followed. Outcomes measured included procedural complication rates, reconstruction patency, limb salvage, maintenance of ambulatory status, maintenance of independent living status, survival, symptom resolution, and symptom recurrence.
  
  
  RESULTS
  Of the 1,000 limbs treated, endovascular therapy was used in 64.3% and open surgery in 35.7% of patients; aortoiliac occlusive disease was treated in 70.1% and infrainguinal disease in 29.9% of patients. The overall 30-day periprocedural complication rate was 7.5%, with no notable difference in complication rates when comparing types of treatment or levels of disease. Overall reconstruction primary patency rates were 87.7% and 70.8%; secondary patencies were 97.8% and 93.9%; limb salvage, 100% and 98.8%; and survivals, 95.4% and 76.9%, at 1 and 5 years, respectively. More than 96% of patients maintained independence and ambulatory ability at 5 years. Overall symptom resolution occurred in 78.8%, and symptom recurrence occurred in 18.1% of limbs treated, with slightly higher resolution and recurrence noted in patients treated with endovascular therapy.
  
  
  CONCLUSIONS
  Contemporary treatment of vasculogenic claudication is safe, effective, and predominantly endovascular. These data support a more liberal use of revascularization for patients with claudication and suggest that current nonoperative treatment guidelines may be based more on surgical dogma than on achievable outcomes.
authors.affiliation: Academic Department of Surgery, Greenville Hospital System University Medical Center, Greenville, SC 29605, USA.
authors.forename: Spence M
authors.initials: SM
authors.lastname: Taylor
authors.forename: Corey A
authors.initials: CA
authors.lastname: Kalbaugh
authors.forename: Matthew G
authors.initials: MG
authors.lastname: Healy
authors.forename: Anna L
authors.initials: AL
authors.lastname: Cass
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Gray
authors.forename: Eugene M
authors.initials: EM
authors.lastname: Langan
authors.forename: David L
authors.initials: DL
authors.lastname: Cull
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Carsten
authors.forename: John W
authors.initials: JW
authors.lastname: York
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Snyder
authors.forename: Jerry R
authors.initials: JR
authors.lastname: Youkey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery*; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D018570:Risk Assessment; D015607:Stents; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures