title: Hepatitis B virus genotype A2 harbours an L217R polymorphism which may account for a lower response to adefovir.
authors.forename: Marcelle
authors.initials: M
authors.lastname: Bottecchia
authors.forename: Antonio
authors.initials: A
authors.lastname: Madejón
authors.forename: Julie
authors.initials: J
authors.lastname: Sheldon
authors.forename: Javier
authors.initials: J
authors.lastname: García-Samaniego
authors.forename: Pablo
authors.initials: P
authors.lastname: Barreiro
authors.forename: Vincent
authors.initials: V
authors.lastname: Soriano
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000328:Adult; D019943:Amino Acid Substitution / Q000235:genetics*; D000998:Antiviral Agents / Q000494:pharmacology*; D024882:Drug Resistance, Viral; D005260:Female; D005838:Genotype; D006509:Hepatitis B / Q000821:virology; D006515:Hepatitis B virus / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D020125:Mutation, Missense; D063065:Organophosphonates / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; C053001:adefovir; D000225:Adenine