title: Macrocyclic polyamine-modified poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolith for capillary electrochromatography.
abstract: 1,4,10,13,16-Pentaazatricycloheneicosane-9,17-dione (macrocyclic polyamine)-modified polymer-based monolithic column for CEC was prepared by ring opening reaction of epoxide groups from poly(glycidyl methacrylate-co-ethylene dimethacrylate) (GMA-co-EDMA) monolith with macrocyclic polyamine. Conditions such as reaction time and concentration of macrocyclic polyamine for the modification reaction were optimized to generate substantial EOF and enough chromatographic interactions. Anodic EOF was observed in the pH range of 2.0-8.0 studied due to the protonation of macrcyclic polyamine at the surface of the monolith. Morphology of the monolithic column was examined by SEM and the incorporation of macrocyclic polyamine to the poly(GMA-co-EDMA) monolith was characterized by infrared (IR) spectra. Successful separation of inorganic anions, isomeric benzenediols, and benzoic acid derivatives on the monolithic column was achieved for CEC. In addition to hydrophobic interaction, hydrogen bonding and electrostatic interaction played a significant role in the separation process.
authors.affiliation: Department of Chemistry, Wuhan University, Wuhan, P. R. China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Tian
authors.forename: Fangxing
authors.initials: F
authors.lastname: Yang
authors.forename: Xuemei
authors.initials: X
authors.lastname: Yang
authors.forename: Enqin
authors.initials: E
authors.lastname: Fu
authors.forename: Ying
authors.initials: Y
authors.lastname: Xu
authors.forename: Zhaorui
authors.initials: Z
authors.lastname: Zeng
mesh_terms: D053801:Capillary Electrochromatography / Q000295:instrumentation* / Q000379:methods; D002396:Catechols / Q000302:isolation & purification; D053841:Electroosmosis; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D008768:Methylmethacrylates / Q000138:chemical synthesis / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D002396:Catechols; D006575:Heterocyclic Compounds, 3-Ring; D047028:Macrocyclic Compounds; D008768:Methylmethacrylates; C020347:GMA-EDMA; C034221:catechol