An efficient synthesis of indolo[3,2-a]carbazoles via the novel acid catalyzed reaction of indoles and diaryl-1,2-diones.
A mild and efficient one pot method for the synthesis of indolo[3,2-a]carbazole derivatives by the para-toluenesulfonic acid catalyzed condensation of indole with acyclic 1,2-diones is described. With cyclobutene-1,2-diones the reaction afforded indole substituted carbazole derivatives in good yield.
Nair
Vijay
V
Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (formerly known as RRL) (CSIR), Trivandrum, 695019, Kerala, India. vijaynair_2001@yahoo.com
Nandialath
Vidya
V
Abhilash
Keecherikunnel G
KG
Suresh
Eringathodi
E
D000143:Acids / Q000737:chemistry*; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010658:Phenylglyoxal / Q000031:analogs & derivatives / Q000737:chemistry
D000143:Acids; D002227:Carbazoles; D007211:Indoles; C041514:carbazole; C030374:indole; D010658:Phenylglyoxal; C006697:benzil