Antisense therapy for cancer.
Antisense molecules have the potential to halt a wide variety of diseases through inhibition of target gene expression. Five antisense phosphorothioates are currently in clinical studies for cancer therapy and encouraging early data have been presented recently.
Orr
R M
RM
CRC Centre for Cancer Therapeutics, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK. rosanne@icr.ac.uk
Monia
B P
BP