title: Finite element modeling of cooled-tip probe radiofrequency ablation processes in liver tissue.
abstract: Finite element model of radiofrequency ablation (RFA) with cooled-tip probe in liver has been developed by employing COMSOL Multiphysics software. It describes coupled electric, thermal and sodium chloride solution infiltration flow phenomena taking place during ablation processes. Features of hydraulic capacity, saturation of the tissue by infiltration, and dependency of electrical conductivity on the damage integral of the tissue have been supplied to the model. RFA experiments have validated the model. Physical parameters describing hydraulic capacity and hydraulic conductivity in the tissue, as well as, the relation of electrical conductivity against the value of damage integral have been determined.
authors.affiliation: Department of System Analysis, Kaunas University of Technology, Kaunas, Lithuania. rimantas.barauskas@ktu.lt
authors.forename: Rimantas
authors.initials: R
authors.lastname: Barauskas
authors.forename: Antanas
authors.initials: A
authors.lastname: Gulbinas
authors.forename: Tomas
authors.initials: T
authors.lastname: Vanagas
authors.forename: Giedrius
authors.initials: G
authors.lastname: Barauskas
mesh_terms: D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D017115:Catheter Ablation / Q000706:statistics & numerical data*; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000033:anatomy & histology / Q000502:physiology; D008113:Liver Neoplasms / Q000628:therapy*; D000078702:Radiofrequency Therapy; D013552:Swine