2-[N-(X-chlorophenyl)carbamoyl]benzenesulfonamide (with X = 2 and 4).
The structures of 2-[N-(2-chlorophenyl)carbamoyl]benzenesulfonamide and 2-[N-(4-chlorophenyl)carbamoyl]benzenesulfonamide, both C(13)H(11)ClN(2)O(3)S, are stabilized by extensive intra- and intermolecular hydrogen bonds. In both structures, sulfonamide groups are hydrogen bonded via the N and O atoms and form chains of molecules. The carbamoyl groups are also hydrogen bonded, involving the O and N atoms, further strengthening the polymeric chains running along the c and a axes in the 2- and 4-chloro derivatives, respectively. Carbamoylsulfonamide derivatives are novel compounds with a great potential for medicinal applications.
Siddiqui
Waseeq Ahmad
WA
Department of Chemistry, University of Sargodha, Sargodha, Pakistan.
Ahmad
Saeed
S
Khan
Islam Ullah
IU
Siddiqui
Hamid Latif
HL
Parvez
Masood
M
D003460:Crystallization; D006860:Hydrogen Bonding; D015394:Molecular Structure; D013449:Sulfonamides / Q000737:chemistry*; D000096926:Benzenesulfonamides
D013449:Sulfonamides; D000096926:Benzenesulfonamides; C529758:2-(N-(2-chlorophenyl)carbamoyl)benzenesulfonamide; C529759:2-(N-(4-chlorophenyl)carbamoyl)benzenesulfonamide