A case of Listeria meningoencephalitis complicated by hydrocephalus in an immunocompetent infant.
We report a very unusual case of meningoencephalitis due to Listeria monocytogenes in a 7-month-old immunocompetent boy. Cerebrospinal fluid (CSF) culture was initially negative, but was positive on the seventh day. The disease was complicated by seizures and hydrocephalus managed with temporary ventriculostomy. The infant was discharged without obvious neurological sequelae after 30 days and developed without neurological or developmental sequelae at two years of age. Listeria is difficult to isolate and is not susceptible to third-generation cephalosporins commonly used for the empirical treatment of bacterial meningitis.
Platnaris
Antonios
A
3rd Pediatric Department, Aristotle University, Hippokration Hospital, Konstantinoupoleos 49, 54642, Thessaloniki, Greece.
Hatzimichael
Athanasios
A
Ktenidou-Kartali
Sofia
S
Kontoyiannides
Kosmas
K
Kollios
Konstantinos
K
Anagnostopoulos
John
J
Roilides
Emmanuel
E
D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D006849:Hydrocephalus / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D007121:Immunocompetence; D007223:Infant; D008297:Male; D008584:Meningitis, Listeria / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D010672:Phenytoin / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000927:Anticonvulsants; D005839:Gentamicins; D010672:Phenytoin; D014640:Vancomycin; D002443:Ceftriaxone; D000667:Ampicillin