title: A case of Listeria meningoencephalitis complicated by hydrocephalus in an immunocompetent infant.
abstract: We report a very unusual case of meningoencephalitis due to Listeria monocytogenes in a 7-month-old immunocompetent boy. Cerebrospinal fluid (CSF) culture was initially negative, but was positive on the seventh day. The disease was complicated by seizures and hydrocephalus managed with temporary ventriculostomy. The infant was discharged without obvious neurological sequelae after 30 days and developed without neurological or developmental sequelae at two years of age. Listeria is difficult to isolate and is not susceptible to third-generation cephalosporins commonly used for the empirical treatment of bacterial meningitis.
authors.affiliation: 3rd Pediatric Department, Aristotle University, Hippokration Hospital, Konstantinoupoleos 49, 54642, Thessaloniki, Greece.
authors.forename: Antonios
authors.initials: A
authors.lastname: Platnaris
authors.forename: Athanasios
authors.initials: A
authors.lastname: Hatzimichael
authors.forename: Sofia
authors.initials: S
authors.lastname: Ktenidou-Kartali
authors.forename: Kosmas
authors.initials: K
authors.lastname: Kontoyiannides
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Kollios
authors.forename: John
authors.initials: J
authors.lastname: Anagnostopoulos
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Roilides
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D006849:Hydrocephalus / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D007121:Immunocompetence; D007223:Infant; D008297:Male; D008584:Meningitis, Listeria / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D010672:Phenytoin / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000927:Anticonvulsants; D005839:Gentamicins; D010672:Phenytoin; D014640:Vancomycin; D002443:Ceftriaxone; D000667:Ampicillin