Mesenchymal stem cells for tissue engineering and regenerative medicine.
Mesenchymal stem cells (MSCs) exist in bone marrow and other musculoskeletal tissues. These cells contribute to the homeostasis of musculoskeletal tissue as well as support for the growth and differentiation of primitive hemopoietic cells. Recent advancements in tissue engineering and regenerative medicine have highlighted MSCs as a potential source of cells which would differentiate to a variety of tissue tailored to individual needs. This paper briefly outlines the current status of MSCs, focusing on their biological characteristics and potential for clinical applications.
Tae
Suk-Kee
SK
Department of Orthopaedics, Dongguk University International Hospital, Goyang, Korea.
Lee
Seok-Hyn
SH
Park
Jae-Sik
JS
Im
Gun-Il
GI
D000818:Animals; D002454:Cell Differentiation; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology*; D044968:Regenerative Medicine / Q000379:methods*; D023822:Tissue Engineering / Q000379:methods*