Osseous metaplasia in an ulcerating tubular adenoma of the colon: a case report.
BACKGROUND
Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology.


METHODS
A 63-year-old woman, who presented with a history of melaena, was found at colonoscopy to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma.


CONCLUSIONS
Heterotopic ossification in colonic adenomas is a particularly rare phenomenon, with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear.
White
Victoria
V
School of Graduate Medicine and Health, University of Nottingham United Kingdom, Derby, UK. mzyyvaw@nottingham.ac.uk
Shaw
Aidan G
AG
Tierney
Gillian M
GM
Lund
Jonathan N
JN
Semeraro
David
D