Determination of dopamine in the presence of ascorbic acid using poly(3,5-dihydroxy benzoic acid) film modified electrode.
A polymerized film of 3,5-dihydroxy benzoic acid (DBA) was prepared on the surface of a glassy carbon electrode (GCE) in neutral solution by cyclic voltammetry (CV). The poly(DBA) film-coated GCE exhibited excellent electrocatalytic activity toward the oxidation of dopamine (DA). A linear range of 1.0 x 10(-7) to 1.0 x 10(-4)M and a detection limit of 6.0 x 10(-8)M were observed in pH 7.4 phosphate buffer solutions. Moreover, the interference of ascorbic acid (AA) was effectively eliminated. This work provides a simple and easy approach to selective detection of DA in the presence of AA.
Hou
Shurong
S
College of Chemistry and Chemical Engineering, Graduate University, Chinese Academy of Sciences, 100049 Beijing, China.
Zheng
Na
N
Feng
Haiyan
H
Li
Xiangjun
X
Yuan
Zhuobin
Z
D001205:Ascorbic Acid / Q000737:chemistry*; D001565:Benzoates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D004298:Dopamine / Q000032:analysis*; D004563:Electrochemistry; D004566:Electrodes; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry; D011199:Potentiometry; D015203:Reproducibility of Results
D001565:Benzoates; D011108:Polymers; C532416:poly(3,5-dihydroxy benzoic acid); D002244:Carbon; D001205:Ascorbic Acid; D004298:Dopamine