title: Coating of bone-like apatite for development of bioactive materials for bone reconstruction.
abstract: Materials with bioactivity, i.e. bone-bonding ability, form a bone-like apatite layer on their surfaces in the body and bond to living bone through this bone-like apatite layer. Bone-like apatite is carbonated hydroxyapatite with small crystallites and low crystallinity. The coating of the bone-like apatite layer on the substrates is expected to be a useful technique to induce bioactivity on the substrates. The bone-like apatite layer can be formed on the surface of substrates in a solution mimicking body fluid when some functional groups are introduced to the substrates. This process is called a biomimetic process. Coating of bone-like apatite layers through this biomimetic process has received much attention in the fabrication of novel composites with bioactivity. An overview of the coating of bone-like apatite is described.
authors.affiliation: Graduate School of Environmental Studies, Tohoku University, 6-6-20, Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan. kamitaka@mail.kankyo.tohoku.ac.jp
authors.forename: Masanobu
authors.initials: M
authors.lastname: Kamitakahara
authors.forename: Chikara
authors.initials: C
authors.lastname: Ohtsuki
authors.forename: Toshiki
authors.initials: T
authors.lastname: Miyazaki
mesh_terms: D000818:Animals; D001031:Apatites / Q000737:chemistry*; D001861:Bone Regeneration / Q000502:physiology*; D018786:Bone Substitutes / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D020099:Coated Materials, Biocompatible