Chemoradiation therapy followed by endoscopic submucosal dissection for esophageal cancer.
We performed chemoradiation therapy (CRT) followed by an endoscopic submucosal dissection (ESD) for three patients with esophageal cancer. One patient refused surgery, and two patients were complicated with severe cardiopulmonary diseases. In all patients, CRT was effective in reducing tumor size, and the residual tumors were completely resected by ESD. All patients were recurrence-free for 6 months to 2.5 years. The combination of CRT plus subsequent ESD may be useful for treating patients with esophageal cancer who are not fit to undergo surgery.
Saito
Yasuharu
Y
Division of Endoscopy, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, Japan. ysaito@belle.shiga-med.ac.jp
Andoh
Akira
A
Hata
Kazunori
K
Tsujikawa
Tomoyuki
T
Ogawa
Atsuhiro
A
Nakahara
Tamio
T
Kushima
Ryouji
R
Fujiyama
Yoshihide
Y
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D003131:Combined Modality Therapy; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000187:drug effects / Q000528:radiation effects / Q000601:surgery; D011878:Radiotherapy
D000970:Antineoplastic Agents