title: Association of Hb Q-Thailand with heterozygous Hb E in a Chinese patient.
abstract: We describe a Chinese patient who was heterozygous for both Hb Q-Thailand [alpha74(EF3)Asp-->His] and Hb E [beta26(B7)Gly-->Asp, GAG-->GTG]. Interaction of the alpha(Q-Thailand) and beta(E) chains leads to a hemoglobin (Hb) variant, namely Hb QE, which differs in electrophoretic mobility and high performance liquid chromatography (HPLC) profiles and in the amount of the Hb Q-Thailand variant present in the blood.
authors.affiliation: Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Dongzhi
authors.initials: D
authors.lastname: Li
authors.forename: Can
authors.initials: C
authors.lastname: Liao
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Xingmei
authors.initials: X
authors.lastname: Xie
authors.forename: Huizhu
authors.initials: H
authors.lastname: Zhong
mesh_terms: D000328:Adult; D044466:Asian People; D002648:Child; D005260:Female; D006446:Hemoglobin E / Q000031:analogs & derivatives* / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D008297:Male; D006442:Glycated Hemoglobin
chemical_list: D006446:Hemoglobin E; D006455:Hemoglobins, Abnormal; C032271:glycated hemoglobin E; D006442:Glycated Hemoglobin; C049214:hemoglobin Q Thailand