title: Do stillborns with no identifiable pathology have leaner cords than liveborns?
abstract: OBJECTIVE
  To evaluate whether stillbirths with no explanation found at autopsy have thinner cords than live, gestational-age-matched controls.
  
  
  METHODS
  Stillbirth autopsies performed at University Hospital, Newark, New Jersey, from January 1995 to October 2002 were reviewed. Cases with no explanation for the death at autopsy had their umbilical cord diameters compared to those in 3 groups of age-matched controls: stillbirths with an identifiable cause of death, liveborns with placentas submitted for pathology evaluation and liveborns from which the placentas were not submitted to pathology. Age-adjusted ANOVAs were performed for comparisons.
  
  
  RESULTS
  Of 181 autopsies performed during the review period, 21 cases (11.6%) provided no information at autopsy that would explain or contribute to an understanding of the death. There was no significant difference in cord diameters between either group ofstillbirths or the pathology-submitted controls. Third-trimester placentas from liveborns without placental submission to pathology had significantly greater cord diameters (p = 0.001).
  
  
  CONCLUSIONS
  This study does not support the theory that a cord accident or decreased umbilical blood flow resulting from a leaner umbilical cord can explain a significant number of stillbirths with no other findings at autopsy. However, it supports the literature in that leaner cords appear to be associated with a wide variety of adverse perinatal conditions.
authors.affiliation: Department of Obstetrics, Gynecology and Women's Health, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark 07101, USA.
authors.forename: Natalie
authors.initials: N
authors.lastname: Roche
authors.forename: Joan
authors.initials: J
authors.lastname: Skurnick
authors.forename: Keleicia
authors.initials: K
authors.lastname: Brown
authors.forename: Debra S
authors.initials: DS
authors.lastname: Heller
mesh_terms: D001344:Autopsy; D016022:Case-Control Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D050498:Live Birth; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011264:Pregnancy Trimesters; D050497:Stillbirth; D014470:Umbilical Cord / Q000473:pathology*