Epigenome sequencing comes of age.
Epigenetic states are responsive to developmental and environmental signals, and as a consequence a eukaryotic cell can have many different epigenomes. In this issue of Cell, Lister et al. (2008) present the floral epigenome of Arabidopsis using next-generation sequencing technology to analyze both DNA methylation at single-base resolution and the expression of small RNAs.
Zhu
Jian-Kang
JK
Botany and Plant Sciences, University of California, Riverside, CA 92508, USA. jian-kang.zhu@ucr.edu
D017360:Arabidopsis / Q000235:genetics*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D018506:Gene Expression Regulation, Plant; D017422:Sequence Analysis, DNA