title: A sporadic case of paraganglioma undetected by urine metabolite screening.
abstract: Phaeochromocytoma is a rare cause of hypertension in children, but important to be recognised, as hypertension can be severe and surgery is often curative. Here, we report on a 7-year-old boy with a phaeochromocytoma, who had normal levels of commonly assayed catecholamine metabolites in the urine. Postoperatively, the patient developed renal vein thrombosis. Appropriate screening tests for phaeochromocytomas, peri-operative management, and the high incidence of an underlying genetic basis, even in sporadic cases, are discussed.
authors.affiliation: Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK. detlef.bockenhauer@nhs.net
authors.forename: Detlef
authors.initials: D
authors.lastname: Bockenhauer
authors.forename: Lesley
authors.initials: L
authors.lastname: Rees
authors.forename: Hartmut
authors.initials: H
authors.lastname: Neumann
authors.forename: Ying
authors.initials: Y
authors.lastname: Foo
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000235:genetics; D002648:Child; D005820:Genetic Testing; D006719:Homovanillic Acid / Q000652:urine*; D006801:Humans; D008297:Male; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000235:genetics; D014642:Vanilmandelic Acid / Q000652:urine*
chemical_list: D014642:Vanilmandelic Acid; D006719:Homovanillic Acid