Expression of the Ha-ras suppressor family member 5 gene in the maturing rat testis.
We analyzed the gene expression of Ha-ras suppressor family member 5 (Hrasls5), which is considered to modulate the Ha-ras signaling cascade, from maturing rat testis. Expression was detected primarily in the spermatocytes in the maturing rat testis. The Hrasls5 gene product might function as a tumor suppressor as well as in spermatogenesis, as deduced from its amino acid sequence.
Yamano
Yoshiaki
Y
Laboratory of Veterinary Biochemistry, Faculty of Agriculture, Tottori University, Japan. yyamano@muses.tottori-u.ac.jp
Asano
Atsushi
A
Ohyama
Kenji
K
Ohta
Masanori
M
Nishio
Ren
R
Morishima
Isao
I
D000818:Animals; D018507:Gene Expression Regulation, Developmental; D008297:Male; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013090:Spermatocytes / Q000166:cytology / Q000378:metabolism; D013091:Spermatogenesis; D013737:Testis / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000235:genetics* / Q000378:metabolism
C530311:Plaat5 protein, rat; D012333:RNA, Messenger; D025521:Tumor Suppressor Proteins