title: SYCAMORE--a systems biology computational analysis and modeling research environment.
abstract: SYCAMORE is a browser-based application that facilitates construction, simulation and analysis of kinetic models in systems biology. Thus, it allows e.g. database supported modelling, basic model checking and the estimation of unknown kinetic parameters based on protein structures. In addition, it offers some guidance in order to allow non-expert users to perform basic computational modelling tasks.
  
  
  BACKGROUND
  SYCAMORE is freely available for academic use at http://sycamore.eml.org. Commercial users may acquire a license.
  
  
  BACKGROUND
  ursula.kummer@bioquant.uni-heidelberg.de.
authors.affiliation: Scientific Databases and Visualization Group, EML Research, Schloss-Wolfsbrunnenweg 33, 69118 Heidelberg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Weidemann
authors.forename: Stefan
authors.initials: S
authors.lastname: Richter
authors.forename: Matthias
authors.initials: M
authors.lastname: Stein
authors.forename: Sven
authors.initials: S
authors.lastname: Sahle
authors.forename: Ralph
authors.initials: R
authors.lastname: Gauges
authors.forename: Razif
authors.initials: R
authors.lastname: Gabdoulline
authors.forename: Irina
authors.initials: I
authors.lastname: Surovtsova
authors.forename: Nils
authors.initials: N
authors.lastname: Semmelrock
authors.forename: Bruno
authors.initials: B
authors.lastname: Besson
authors.forename: Isabel
authors.initials: I
authors.lastname: Rojas
authors.forename: Rebecca
authors.initials: R
authors.lastname: Wade
authors.forename: Ursula
authors.initials: U
authors.lastname: Kummer
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D020407:Internet; D008954:Models, Biological; D012107:Research Design; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D049490:Systems Biology / Q000379:methods*; D014584:User-Computer Interface