HSP60 is a rare cause of hereditary spastic paraparesis, but may act as a genetic modifier.
Hewamadduma
C A A
CA
Academic Neurology Unit, Medical School, Beech Hill Road, University of Sheffield, S10 2RX, UK. channa.hewamadduma@sth.nhs.uk
Kirby
J
J
Kershaw
C
C
Martindale
J
J
Dalton
A
A
McDermott
C J
CJ
Shaw
P J
PJ
D000251:Adenosine Triphosphatases / Q000235:genetics; D000293:Adolescent; D000328:Adult; D018834:Chaperonin 60 / Q000235:genetics*; D025063:Chromosome Disorders / Q000235:genetics; D004252:DNA Mutational Analysis; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D005799:Genes, Dominant / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics*; D010375:Pedigree; D015419:Spastic Paraplegia, Hereditary / Q000235:genetics* / Q000378:metabolism* / Q000503:physiopathology; D000074181:Spastin
D018834:Chaperonin 60; D005819:Genetic Markers; D000251:Adenosine Triphosphatases; D000074181:Spastin; C400283:SPAST protein, human