title: [A case of subacute necrotizing lymphadenitis with recurrent aseptic meningitis 11 years after the first episode].
abstract: We report a 29-year-old man with subacute necrotizing lymphadenitis (SNL) associated with recurrent aseptic meningitis following an 11-year remission period. In both episodes, headache and fever were followed by lymphadenopathy, with increased serum IgE level. Although pleocytosis in cerebrospinal fluid was confirmed at admission in the first episode, it appeared at one week after admission in the second episode. Administration of glucocorticoid was effective for treating meningitis. The present case suggests a pathomechanism for SNL that involves both an immunological background and an acute viral infection as triggers of exacerbation of aseptic meningitis.
authors.affiliation: Department of Neurology, Saitama Medical University.
authors.forename: Kaori
authors.initials: K
authors.lastname: Itokawa
authors.forename: Miki
authors.initials: M
authors.lastname: Fukui
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Naotoshi
authors.initials: N
authors.lastname: Tamura
authors.forename: Seiya
authors.initials: S
authors.lastname: Sannohe
authors.forename: Kunio
authors.initials: K
authors.lastname: Shimazu
mesh_terms: D000328:Adult; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications*; D006801:Humans; D008297:Male; D008582:Meningitis, Aseptic / Q000150:complications*; D012008:Recurrence