title: Intrathecal baclofen: expanding treatment options for hypertonicity.
abstract: Adequate assessment and treatment of hypertonia has remained a challenging problem for physicians. Differentiating between the various characteristics of hypertonicity can lead to improved treatment options. While oral medications, focal chemo-denervation, chemical neurolysis and orthopedic surgeries continue to play a role in the management of pathologic tone, intrathecal delivery of baclofen has proven to be a safe and effective treatment in the clinical setting of hypertonia.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Missouri Health Care, Missouri, USA. faridrez@health.missouri.edu
authors.forename: Rez
authors.initials: R
authors.lastname: Farid
mesh_terms: D001418:Baclofen / Q000008:administration & dosage*; D018755:GABA Agonists / Q000008:administration & dosage*; D006801:Humans; D015918:Infusion Pumps, Implantable; D007278:Injections, Spinal; D009122:Muscle Hypertonia / Q000188:drug therapy*
chemical_list: D018755:GABA Agonists; D001418:Baclofen