title: Cluster analysis of mortality and malformations in the Provinces of Naples and Caserta (Campania Region).
abstract: The possible adverse health effects associated with the residence in the neighbourhood of toxic dump sites have been the object of many epidemiological studies in the last two decades;some of these reported increases of various health outcomes. The present study reports the cluster analysis of mortality and malformations at municipality level, standardized by socioeconomic deprivation index, in an area of the Campania Region characterized by a widespread illegal practice of dumping toxic and urban waste. Clusters have been observed with significant excess of mortality by lung, liver, gastric, kidney and bladder cancers and of prevalence of total malformations and malformations of limb, cardiovascular and urogenital system. The clusters are concentrated in a sub-area where most of the illegal practice of dumping toxic waste has taken place
authors.affiliation: Dipartimento Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanità, Rome, Italy. lucia.fazzo@iss.it
authors.forename: Lucia
authors.initials: L
authors.lastname: Fazzo
authors.forename: Stefano
authors.initials: S
authors.lastname: Belli
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Minichilli
authors.forename: Francesco
authors.initials: F
authors.lastname: Mitis
authors.forename: Michele
authors.initials: M
authors.lastname: Santoro
authors.forename: Lucia
authors.initials: L
authors.lastname: Martina
authors.forename: Renato
authors.initials: R
authors.lastname: Pizzuti
authors.forename: Pietro
authors.initials: P
authors.lastname: Comba
authors.forename: Marco
authors.initials: M
authors.lastname: Martuzzi
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Bianchi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D015331:Cohort Studies; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality*; D005260:Female; D006256:Hazardous Waste / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology / Q000401:mortality*; D012307:Risk Factors
chemical_list: D006256:Hazardous Waste