Serum bFGF concentrations in gastric cancer patients.
BACKGROUND
Angiogenetic factors play an important role in the formation of new blood vessels involved in the growth and metastatic spread of solid tumors, but there is limited information regarding the clinical significance of serum bFGF levels in gastric cancer patients.


METHODS
Serum bFGF concentrations were measured by quantitative sandwich enzyme immunoassay technique in 30 controls and in 30 gastric cancer patients before surgery. The association between preoperative serum bFGF levels and clinical pathological features were evaluated.


RESULTS
Preoperative serum bFGF levels in patients with gastric cancer were significantly higher than those in control patients (p=0.027). On the other hand; there is no relationship between serum bFGF levels and clinical-pathologic parameters in gastric cancer patients.


CONCLUSIONS
Circulating bFGF might not be a marker suitable for assessing tumor progression (Tab. 1, Ref. 7). Full Text (Free, PDF) www.bmj.sk.
Bilgic
I
I
Fifth Department of Surgery, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Ozalp
N
N
Tez
M
M
Koc
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D016222:Fibroblast Growth Factor 2 / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000097:blood* / Q000601:surgery
D016222:Fibroblast Growth Factor 2