Small ruminant lentivirus proviral sequences from wild ibexes in contact with domestic goats.
Small ruminant lentiviruses (SRLV) are widespread amongst domesticated goats and sheep worldwide, but have not been clearly identified in wild small ruminants, where they might constitute an animal health risk through contamination from local domesticates. SRLV proviruses from three ibexes from the French Alps are described and sequences from their gag gene and long terminal repeats (LTRs) were compared with sequences from local goats and goat/ibex hybrids. The ibex and hybrid proviruses formed a closely related group with <2 % nucleotide difference. Their LTRs were clearly distinct from those of local goats or reference SRLV sequences; however, their gag sequences resembled those from one local goat and reference sequences from caprine arthritis encephalitis virus rather than visna/maedi virus. One SRLV-positive ibex from a distant site shared similarities with the other ibexes studied in both its gag and LTR sequences, suggesting that a distinct SRLV population could circulate in some wild ibex populations.
Erhouma
Esadk
E
INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|Université Lyon 1, F-69007 Lyon, France.|Ecole Pratique des Hautes Etudes, Lyon, France.
Guiguen
François
F
Ecole Nationale Vétérinaire de Lyon, Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Université Lyon 1, F-69007 Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|Ecole Pratique des Hautes Etudes, Lyon, France.|Université de Lyon, F-69007 Lyon, France.
Chebloune
Yahia
Y
Ecole Pratique des Hautes Etudes, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|Université Lyon 1, F-69007 Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.
Gauthier
Dominique
D
Laboratoire Départemental Vétérinaire, Gap, France.
Lakhal
Laila Mselli
LM
IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Ecole Pratique des Hautes Etudes, Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|Université Lyon 1, F-69007 Lyon, France.
Greenland
Timothy
T
Ecole Pratique des Hautes Etudes, Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|Université Lyon 1, F-69007 Lyon, France.
Mornex
Jean François
JF
IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Ecole Pratique des Hautes Etudes, Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|Université Lyon 1, F-69007 Lyon, France.|Hospices Civils de Lyon, Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.
Leroux
Caroline
C
Ecole Pratique des Hautes Etudes, Lyon, France.|INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|Université Lyon 1, F-69007 Lyon, France.
Alogninouwa
Théodore
T
INRA, UMR754 'Rétrovirus et Pathologie Comparée', Lyon, France.|IFR128 BioSciences Gerland Lyon Sud, Lyon, France.|Ecole Pratique des Hautes Etudes, Lyon, France.|Ecole Nationale Vétérinaire de Lyon, Lyon, France.|Université de Lyon, F-69007 Lyon, France.|Université Lyon 1, F-69007 Lyon, France.
D000595:Amino Acid Sequence; D000818:Animals; D000835:Animals, Wild / Q000821:virology; D005260:Female; D005602:France; D015683:Gene Products, gag / Q000235:genetics; D015511:Goat Diseases / Q000821:virology*; D006041:Goats / Q000821:virology; D016086:Lentivirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D016180:Lentivirus Infections / Q000662:veterinary* / Q000821:virology; D008297:Male; D008969:Molecular Sequence Data; D011533:Proviruses / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D016415:Sequence Alignment; D013045:Species Specificity; D020079:Terminal Repeat Sequences / Q000235:genetics
D015683:Gene Products, gag