An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis.
Diisopropylsilyl ethers were activated with N-bromosuccinimide, and reacted with a fluorous-tagged alcohol, to yield tethered substrates for ring-closing metathesis reactions.
Cordier
Christopher
C
School of Chemistry, University of Leeds, Leeds, UK, LS2 9JT.
Morton
Daniel
D
Leach
Stuart
S
Woodhall
Thomas
T
O'Leary-Steele
Catherine
C
Warriner
Stuart
S
Nelson
Adam
A
D003432:Cross-Linking Reagents / Q000737:chemistry; D017611:Fluorine Compounds / Q000737:chemistry; D047028:Macrocyclic Compounds / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D003432:Cross-Linking Reagents; D017611:Fluorine Compounds; D047028:Macrocyclic Compounds; D012821:Silanes