title: Abdominal sacrocolpopexy: anatomic outcomes and complications with Pelvicol, autologous and synthetic graft materials.
abstract: OBJECTIVE
  The purpose of this study was to compare anatomic outcomes and graft-related complications (GRCs) for abdominal sacrocolpopexy (ASC) with Pelvicol (CR BARD, Murray Hill, NJ), autologous fascia, and synthetic grafts.
  
  
  METHODS
  This is a retrospective cohort study of ASC from 2001-2005. We reviewed anatomic outcomes and GRCs. Apical failure was defined as >stage 0.
  
  
  RESULTS
  Of 259 ASC procedures, Pelvicol was used in 102 procedures (39%); synthetic mesh in 134 procedures (52%), and autologous fascia in 23 procedures (9%). Mean postoperative follow up was 1.1 years. Apical failure by graft group were Pelvicol 10 (11%), synthetics 1 (1%), and autologous 1 (7%; P = .011). All 7 reoperations for apical prolapse were in the Pelvicol group. GRCs occurred in 16% of the cases, with a higher proportion of erosions in the Pelvicol group (11% vs 3% and 4%; P = .045). Reoperations as a result of GRC were similar between groups.
  
  
  CONCLUSIONS
  ASC is more likely to fail with Pelvicol than with synthetic or autologous grafts. The use of Pelvicol did not reduce graft-related complications in this population.
authors.affiliation: Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. lquiroz1@jhmi.edu
authors.forename: Lieschen H
authors.initials: LH
authors.lastname: Quiroz
authors.forename: Robert E
authors.initials: RE
authors.lastname: Gutman
authors.forename: Stuart
authors.initials: S
authors.lastname: Shippey
authors.forename: Geoffery W
authors.initials: GW
authors.lastname: Cundiff
authors.forename: Tatiana
authors.initials: T
authors.lastname: Sanses
authors.forename: Joan L
authors.initials: JL
authors.lastname: Blomquist
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Handa
mesh_terms: D000328:Adult; D000368:Aged; D005205:Fascia / Q000637:transplantation; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D019736:Prostheses and Implants; D012086:Reoperation; D012189:Retrospective Studies; D012447:Sacrum / Q000601:surgery; D013526:Surgical Mesh; D013536:Suture Techniques; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000601:surgery*