title: Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail.
abstract: Exocytosis inhibitor Exo 1, dynamin inhibitory peptide (inhibitor of endocytosis), and colchicine disturb short-term potentiation of cholinosensitivity of defensive behavior command neurons in edible snail induced by rhythmic electrical orthodromic stimulation. We hypothesize that the short-term potentiation of cholinosensitivity in the extra-synaptic membrane develops due to incorporation of extra cholinoceptors into neuron plasmalemma as a result of enhanced recycling of the internalized cholinoceptors with participation of microtubules.
authors.affiliation: Department of Higher Nervous Activity, M. V. Lomonosov Moscow State University.
authors.forename: M S
authors.initials: MS
authors.lastname: Abramova
authors.forename: D A
authors.initials: DA
authors.lastname: Makhnovskii
authors.forename: A S
authors.initials: AS
authors.lastname: Pivovarov
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism; D003078:Colchicine / Q000378:metabolism; D006372:Helix, Snails; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism; D011950:Receptors, Cholinergic / Q000378:metabolism*; D050257:Tubulin Modulators / Q000378:metabolism
chemical_list: D010455:Peptides; D011950:Receptors, Cholinergic; D050257:Tubulin Modulators; D000109:Acetylcholine; D003078:Colchicine