Gold(III)-mediated aldol condensations provide efficient access to nitrogen heterocycles.
Quinolines, dihydroquinolines, and aza-xanthones can be synthesized efficiently and under mild reaction conditions by means of a reaction sequence employing Au(III)-catalyzed aldol reactions as the key step.
Waldmann
Herbert
H
Max-Planck-Institut Für Molekulare Physiologie, Abteilung Chemische Biologie, Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de
Karunakar
Galla V
GV
Kumar
Kamal
K
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*
D000447:Aldehydes; D006571:Heterocyclic Compounds; D006046:Gold; C116609:3-hydroxybutanal; D009584:Nitrogen