Direct synthesis of bicyclic guanidines through unprecedented palladium(ii) catalysed diamination with copper chloride as oxidant.
Palladium catalysed intramolecular guanidine transfer to alkenes can be accomplished with copper chloride as the oxidant to give bicyclic guanidines with complete selectivity and in high yields.
Hövelmann
Claas H
CH
Institut de Chimie, UMR 7177, Université Louis Pasteur, Strasbourg Cedex, France.
Streuff
Jan
J
Brelot
Lydia
L
Muñiz
Kilian
K
D000586:Amination; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D006146:Guanidines / Q000138:chemical synthesis* / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
D006146:Guanidines; D016877:Oxidants; D010165:Palladium; D003300:Copper; C029892:cupric chloride