title: Risk factors for abdominal donor-site morbidity in free flap breast reconstruction.
abstract: BACKGROUND
  The lower abdomen is the most popular donor site for autologous tissue breast reconstruction. Several studies have reported abdominal morbidity following pedicled and free flap reconstructions using this donor site, yet few studies have compared the various types of free flaps and investigated specific operative and patient-related factors that are associated with higher rates of abdominal complications.
  
  
  METHODS
  The authors conducted a retrospective review of all free flap breast reconstructions performed at University of California Los Angeles Medical Center between July of 2002 and July of 2005.
  
  
  RESULTS
  A total of 279 patients underwent 211 unilateral and 68 bilateral reconstructions, totaling 347 flaps. Eleven percent were free transverse rectus abdominis myocutaneous (TRAM) flaps, 52 percent were muscle-sparing free TRAM flaps, and 37 percent were deep inferior epigastric perforator (DIEP) flaps. Mean follow-up was 29.9 months. There were 30 total abdominal complications (10.9 percent of patients), including 17 rectus bulges and five hernias. Free TRAM reconstructions had a significantly higher rate of donor-site complications than did DIEP reconstructions. Bilateral flap harvests and obesity (body mass index >30) were significant risk factors for (1) any donor-site complication and (2) rectus bulge/hernia formation. There was no significant increase in donor-site complications associated with various prior abdominal operations.
  
  
  CONCLUSIONS
  Donor-site complications are not uncommon, but paying careful attention to patient comorbidities when selecting an operative approach (bilateral versus unilateral, free TRAM versus DIEP, and so on) can minimize postoperative abdominal complications. Furthermore, the results corroborate the recent literature suggesting there is little functional difference in patients receiving muscle-sparing free TRAM versus DIEP reconstructions.
authors.affiliation: Los Angeles, Calif. From the Division of Plastic and Reconstructive Surgery, University of California Los Angeles School of Medicine.
authors.forename: Raj M
authors.initials: RM
authors.lastname: Vyas
authors.forename: Brian P
authors.initials: BP
authors.lastname: Dickinson
authors.forename: Jaco H
authors.initials: JH
authors.lastname: Fastekjian
authors.forename: James P
authors.initials: JP
authors.lastname: Watson
authors.forename: Andrew L
authors.initials: AL
authors.lastname: DaLio
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Crisera
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015331:Cohort Studies; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D046449:Hernia, Abdominal / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D012307:Risk Factors; D013524:Surgical Flaps; D013526:Surgical Mesh; D013536:Suture Techniques; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014945:Wound Healing