title: [Effects of skin infiltration with ropivacaine 0,75% on postoperative pain after caesarean section].
abstract: OBJECTIVE
  Evaluate the effects of skin infiltration with ropivacaine 0,75% on postoperative pain after caesarean section in the first 24h.
  
  
  METHODS
  A prospective randomized double blind study was realized during three months in Auxerre Hospital. All ASA 1-2 patients presenting for elective caesarean section under spinal anesthesia were enrolled in the study. Drug addicts and patients with chronic pain were excluded from the study. The patients were randomly divided into two groups to receive skin infiltration 20 ml of ropivacaine 0,75% (Gr R) or skin infiltration of 20 ml of 0,9% saline solution. All patients received systematically propacetamol 1g per six hours and ketoprofen 50mg per six hours. Intravenous morphine titration was delivered to patients with a simple numerical scale greater or equal to three (SNS> or =3). Postoperative pain (SNS), morphine consumption and adverse reactions were compared.
  
  
  RESULTS
  From July to September 2005, 42 patients were enrolled in the study. The SNS was lower in the Gr R. Total morphine consumption was reduced in the Gr R. The incidence of the adverse effects were higher in the Gr P. One case of parietal haematoma was detected in the Gr P, the evolution of which was favorable.
  
  
  CONCLUSIONS
  Skin infiltration of ropivacaine 0,75% is a simple technique able to reduce postoperative pain score and morphine consumption after caesarean section.
authors.affiliation: Service d'anesthésie, centre hospitalier régional d'Auxerre, 2, boulevard de Verdun, 89011 Auxerre, France. mustaphabens_15rea@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Bensghir
authors.forename: A
authors.initials: A
authors.lastname: Elwali
authors.forename: C
authors.initials: C
authors.lastname: Miller
authors.forename: H
authors.initials: H
authors.lastname: Azendour
authors.forename: M
authors.initials: M
authors.lastname: Drissi
authors.forename: H
authors.initials: H
authors.lastname: Bakkali
authors.forename: L
authors.initials: L
authors.lastname: Belyamani
authors.forename: M
authors.initials: M
authors.lastname: Atmani
authors.forename: N
authors.initials: N
authors.lastname: Drissi Kamili
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000577:Amides / Q000493:pharmacokinetics* / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000493:pharmacokinetics* / Q000627:therapeutic use; D019540:Area Under Curve; D002585:Cesarean Section / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D011247:Pregnancy; D011446:Prospective Studies; D000077212:Ropivacaine; D012869:Skin Absorption / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine