title: Oesophageal perforation following ingestion of over-the-counter ibuprofen capsules.
abstract: OBJECTIVE
  We present a rare case of oesophageal perforation following ingestion of over-the-counter ibuprofen capsules.
  
  
  METHODS
  Case report and literature review of pill oesophagitis.
  
  
  METHODS
  A previously well, 18-year-old man presented with sudden onset, severe, retrosternal pain, dysphagia and odynophagia following ingestion of over-the-counter ibuprofen capsules. Plain X-ray films and a contrast-enhanced computed tomography scan indicated the diagnosis. The patient was successfully treated with non-operative management.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report in the world literature concerning oesophageal perforation with ibuprofen. We discuss pill-induced oesophageal injury and its prevention. Manufacturers, clinicians and patients can all take steps to avoid this potentially life-threatening complication.
authors.affiliation: Department of Otolaryngology, Guy's Hospital and King's College, London. singhn@bigpond.com
authors.forename: N P
authors.initials: NP
authors.lastname: Singh
authors.forename: J G
authors.initials: JG
authors.lastname: Rizk
mesh_terms: D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D002214:Capsules; D004939:Esophageal Perforation / Q000139:chemically induced* / Q000000981:diagnostic imaging; D004947:Esophagus / Q000000981:diagnostic imaging; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008297:Male; D004366:Nonprescription Drugs / Q000009:adverse effects; D011859:Radiography
chemical_list: D018712:Analgesics, Non-Narcotic; D002214:Capsules; D004366:Nonprescription Drugs; D007052:Ibuprofen