title: Acute toxemic schistosomiasis complicated by acute flaccid paraplegia due to schistosomal myeloradiculopathy in Sudan.
abstract: A 55-year old Sudanese physician presented with one month history of diarrhea, loss of weight (10 kg) and low grade nocturnal fever. Following colonoscopy, he rapidly developed paraparesis and retention of urine. Magnetic resonance imaging (MRI) of the spinal cord showed low cord lesion suggestive of transverse myelitis. We present a detailed account of diagnostic and management challenges and a literature review of the final diagnosis of acute toxemic schistosomiasis, complicated by acute flaccid paraplegia due to schistosomal myeloradiculopathy. We are reporting this case to increase the awareness of physicians of schistosomal myeloradiculopathy, as it needs urgent specific treatment praziquantel and steroids. An early follow-up with MRI of the spinal cord (2 weeks treatment) may help in preventing unnecessary neurosurgical intervention. Bilharziasis may be contracted on the banks of the river "White Nile" in urban areas. Finally, clinicians should make use of the Google computer search for diagnosis in difficult cases.
authors.affiliation: Department of Medicine, Faculty of Medicine, Taibah University, Al-Madinah Al-Munawarah. Kingdom of Saudi Arabia. fadlulla2000@hotmail.com
authors.forename: Abdelmonim F
authors.initials: AF
authors.lastname: Ahmed
authors.forename: Abdelrahman S
authors.initials: AS
authors.lastname: Idris
authors.forename: Abid M
authors.initials: AM
authors.lastname: Kareem
authors.forename: Talal A
authors.initials: TA
authors.lastname: Dawoud
mesh_terms: D000208:Acute Disease; D000871:Anthelmintics / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020818:Neuroschistosomiasis / Q000175:diagnosis* / Q000188:drug therapy; D010264:Paraplegia / Q000469:parasitology*; D011843:Radiculopathy / Q000469:parasitology*; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D013397:Sudan
chemical_list: D000871:Anthelmintics