Fibrin formation on fast forward.
Fibrin gel, a 3-dimensional network of fibers constituting the scaffold of the hemostatic plug, is rapidly formed following fibrinogen activation during blood coagulation. In this issue of Blood, Chernysh and Weisel provide the first direct glimpse of the fibrin polymerization process under near-physiological conditions using deconvolution microscopy.
Rocco
Mattia
M
Istituto Nazionale per la Ricerca Sul Cancro (IST), Genova, Italy.