Morphological changes in the ovaries during modeling of functional cysts of hormonal genesis.
Morphological study of ovarian follicular cysts induced by chorionic gonadotropin (300 U) and insulin (Protafane HM; 2.5 U) in adult rats showed that superovulatory dose of chorionic gonadotropin and moderate hyperinsulinemia induced the development of ovarian cysts on days 3-5 in 100% cases. Dynamic study of ovarian morphology showed that changes were reversible and the cysts regressed within 60 days, which confirmed their functional nature.
Logvinov
S V
SV
Department of Histology, Embryology, and Cytology, Siberian State Medical University, Tomsk.
Tikhonovskaya
O A
OA
Petrov
I A
IA
Petrova
M S
MS
Petrina
Y V
YV
Okorokov
A O
AO
D000818:Animals; D006063:Chorionic Gonadotropin / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D007328:Insulin / Q000378:metabolism / Q000494:pharmacology; D010048:Ovarian Cysts / Q000378:metabolism / Q000473:pathology; D010053:Ovary / Q000166:cytology / Q000187:drug effects; D051381:Rats
D006063:Chorionic Gonadotropin; D007328:Insulin