Allicin inhibits blood vessel growth and downregulates Akt phosphorylation and actin polymerization.
Sela
Uri
U
Assaf-Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel. uris@asaf.health.gov.il
Brill
Alexander
A
Kalchenko
Vyacheslav
V
Dashevsky
Olga
O
Hershkoviz
Rami
R
D000199:Actins / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D001011:Aorta / Q000166:cytology / Q000187:drug effects; D002417:Cattle; D002465:Cell Movement / Q000187:drug effects; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000187:drug effects; D004220:Disulfides; D004305:Dose-Response Relationship, Drug; D015536:Down-Regulation; D042783:Endothelial Cells / Q000187:drug effects* / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects; D016222:Fibroblast Growth Factor 2; D006801:Humans; D008297:Male; D008870:Microtubules / Q000187:drug effects; D009389:Neovascularization, Pathologic / Q000517:prevention & control*; D010766:Phosphorylation / Q000187:drug effects*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D051381:Rats; D013441:Sulfinic Acids / Q000494:pharmacology*; D014404:Tubulin / Q000378:metabolism
D000199:Actins; D004220:Disulfides; D013441:Sulfinic Acids; D014404:Tubulin; D016222:Fibroblast Growth Factor 2; C006452:allicin; D051057:Proto-Oncogene Proteins c-akt