title: Increased serum pigment epithelium-derived factor levels in type 1 diabetic patients with diabetic retinopathy.
abstract: Serum pigment epithelium-derived factor (PEDF) levels were significantly higher in type 1 diabetic patients with retinopathy (n=20, 10.38+/-3.87 microg/ml) compared to the patients without it (n=57, 7.68+/-2.80 microg/ml) (p=0.0013). Elevated PEDF levels may be related to the progression of diabetic retinopathy.
authors.affiliation: Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. katakami@medone.med.osaka-u.ac.jp
authors.forename: Naoto
authors.initials: N
authors.lastname: Katakami
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kaneto
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Yamasaki
authors.forename: Munehide
authors.initials: M
authors.lastname: Matsuhisa
mesh_terms: D000293:Adolescent; D000328:Adult; D000419:Albuminuria; D001794:Blood Pressure; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D003930:Diabetic Retinopathy / Q000097:blood*; D005136:Eye Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D009414:Nerve Growth Factors / Q000097:blood*; D015843:Serpins / Q000097:blood*; D000099174:Pigment Epithelium-Derived Factor
chemical_list: D005136:Eye Proteins; D007328:Insulin; D009414:Nerve Growth Factors; D015843:Serpins; D000099174:Pigment Epithelium-Derived Factor