title: Sc(OTf)3-catalyzed or t-BuOK promoted tandem reaction of 2-(2-(alkynyl)benzylidene)malonate with indole.
abstract: Tandem reaction of 2-(2-(alkynyl)benzylidene)malonate with indole was investigated. (Z)-1-Benzylidene-3-(1 H-indol-1-yl)-1 H-indene-2,2(3 H)-dicarboxylate was generated in the presence of t-BuOK at room temperature; whereas 3-((1 H-indol-3-yl)(2-(alkynyl)aryl)methyl)-1 H-indole was obtained when Sc(OTf)3 was utilized as catalyst at 50 degrees C.
authors.affiliation: Department of Chemistry, Fudan University, Shanghai, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Gao
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001597:Benzylidene Compounds / Q000737:chemistry*; D002384:Catalysis; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D008314:Malonates / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D012538:Scandium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001597:Benzylidene Compounds; D007202:Indicators and Reagents; D007211:Indoles; D008314:Malonates; D008698:Mesylates; C436603:scandium triflate; D012538:Scandium