title: Chemoradiation therapy followed by endoscopic submucosal dissection for esophageal cancer.
abstract: We performed chemoradiation therapy (CRT) followed by an endoscopic submucosal dissection (ESD) for three patients with esophageal cancer. One patient refused surgery, and two patients were complicated with severe cardiopulmonary diseases. In all patients, CRT was effective in reducing tumor size, and the residual tumors were completely resected by ESD. All patients were recurrence-free for 6 months to 2.5 years. The combination of CRT plus subsequent ESD may be useful for treating patients with esophageal cancer who are not fit to undergo surgery.
authors.affiliation: Division of Endoscopy, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, Japan. ysaito@belle.shiga-med.ac.jp
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Saito
authors.forename: Akira
authors.initials: A
authors.lastname: Andoh
authors.forename: Kazunori
authors.initials: K
authors.lastname: Hata
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Tsujikawa
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Ogawa
authors.forename: Tamio
authors.initials: T
authors.lastname: Nakahara
authors.forename: Ryouji
authors.initials: R
authors.lastname: Kushima
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Fujiyama
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D003131:Combined Modality Therapy; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000187:drug effects / Q000528:radiation effects / Q000601:surgery; D011878:Radiotherapy
chemical_list: D000970:Antineoplastic Agents