title: Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation.
abstract: Coronary aneurysm formation after drug-eluting stent (DES) implantation is a rare complication with late stent thrombosis as a potentially fatal sequela. One possible mechanism involved in aneurysm formation is thought to be late-acquired stent malapposition due to a local inflammatory response to the polymer and/or the drug. Coronary aneurysm formation has been documented with sirolimus- and paclitaxel-eluting stents. We report a case of coronary aneurysm formation in a patient with an everolimus-eluting stent (EES; Xience(R) Abbott Vascular, Redwood City, California) relatively early (3 months) after stent implantation. This case illustrates that even with second-generation DES like the EES, which is thought to be highly biocompatible, there can be adverse reactions to the polymer and/or to the drug.
authors.affiliation: Department of Cardiology, Stadtspital Triemli, 8063, Zürich, Switzerland. Rainer.Zbinden@triemli.stzh.ch
authors.forename: Rainer
authors.initials: R
authors.lastname: Zbinden
authors.forename: Parham
authors.initials: P
authors.lastname: Eshtehardi
authors.forename: Stéphane
authors.initials: S
authors.lastname: Cook
mesh_terms: D019917:Blood Vessel Prosthesis Implantation; D020099:Coated Materials, Biocompatible / Q000009:adverse effects*; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000628:therapy; D017023:Coronary Angiography; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D000068338:Everolimus; D006801:Humans; D009203:Myocardial Infarction / Q000601:surgery; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives
chemical_list: D020099:Coated Materials, Biocompatible; D000068338:Everolimus; D020123:Sirolimus