Animal models for arthritis.
Animal models for rheumatic diseases complement human investigations to study in detail pathogenic hypotheses and therapeutic strategies. An overview of animal studies in the last years shows examples for ideas taken from bench to bedside and from bedside to bench. Depending on the disease studied, progress includes a refinement of physiological and pathogenic thinking and a better definition of promising cellular and molecular therapeutic targets.
Dinser
Robert
R
Department of Internal Medicine and Rheumatology, Kerckhoff Hospital, Justus-Liebig-University of Giessen, Benekestrasse 2-8, 61231 Bad Nauheim, Germany. r.dinser@kerckhoff-klinik.de <r.dinser@kerckhoff-klinik.de>
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000503:physiopathology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D051379:Mice; D010003:Osteoarthritis / Q000188:drug therapy / Q000503:physiopathology; D011817:Rabbits; D051381:Rats; D012216:Rheumatic Diseases / Q000188:drug therapy / Q000503:physiopathology*; D012455:Salamandridae