title: Secondary syphilis with ocular manifestations in older adults.
abstract: We describe 4 patients (age, >50 years) with secondary syphilis. All patients presented with ocular syphilis, and 2 presented with syphilis-negative rapid plasma reagin titers due to a prozone phenomenon. Three male patients reported sildenafil use. The presentation of these patients with ocular syphilis suggests the need for additional clinical studies involving older patients.
authors.affiliation: United States Naval Medical Research Center Detachment, Lima, Peru. Ryan.Maves@med.navy.mil
authors.forename: Ryan C
authors.initials: RC
authors.lastname: Maves
authors.forename: Edward R
authors.initials: ER
authors.lastname: Cachay
authors.forename: Maile Ann
authors.initials: MA
authors.lastname: Young
authors.forename: Joshua
authors.initials: J
authors.lastname: Fierer
mesh_terms: D000368:Aged; D002308:Cardiolipins / Q000097:blood; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000166:cytology; D002784:Cholesterol / Q000097:blood; D005128:Eye Diseases / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000150:complications* / Q000382:microbiology; D010713:Phosphatidylcholines / Q000097:blood; D010879:Piperazines / Q000627:therapeutic use; D011687:Purines / Q000627:therapeutic use; D011935:Reagins / Q000097:blood; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use
chemical_list: D002308:Cardiolipins; D010713:Phosphatidylcholines; D010879:Piperazines; D011687:Purines; D011935:Reagins; D013450:Sulfones; C054448:VDRL antigen; D002784:Cholesterol; D000068677:Sildenafil Citrate