title: [A case of anti-LKM 1 positive autoimmune hepatitis accompanied by systemic lupus erythematosus].
abstract: Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti-LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis.
authors.affiliation: Department of Internal Medicine, Kwang Myung SungAe Hospital, Gwangmyeong, Korea.
authors.forename: Dae Han
authors.initials: DH
authors.lastname: Choi
authors.forename: Hae Kyung
authors.initials: HK
authors.lastname: Kim
authors.forename: Tae Il
authors.initials: TI
authors.lastname: Park
authors.forename: Byung Min
authors.initials: BM
authors.lastname: John
authors.forename: Sung Hwan
authors.initials: SH
authors.lastname: Kang
authors.forename: Yoon Serk
authors.initials: YS
authors.lastname: Lee
authors.forename: Tae Hyun
authors.initials: TH
authors.lastname: Kim
authors.forename: Uh Joo
authors.initials: UJ
authors.lastname: Lee
authors.forename: Tae Seung
authors.initials: TS
authors.lastname: Lee
authors.forename: Gwi Ok
authors.initials: GO
authors.lastname: Yoon
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D004452:Echocardiography; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008099:Liver / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D055815:Young Adult
chemical_list: D000974:Antibodies, Antinuclear; D001323:Autoantibodies; C060729:anti-liver kidney microsome antibody