title: Automated extraction and preconcentration of multiresidue of pesticides on a micro-solid-phase extraction system based on polypyrrole as sorbent and off-line monitoring by gas chromatography-flame ionization detection.
abstract: A simple and efficient automated method for extraction and preconcentration of some organophosphorus and organochlorine pesticides from drinking and agriculture waters has been developed. In this work, a pyrrole-based polymer was synthesized and applied as an efficient sorbent for micro-solid-phase extraction (mu-SPE). Polypyrrole (PPY) was synthesized by chemical oxidation of the monomer in nonaqueous solution. The mu-SPE of selected pesticides, from aqueous samples was performed using 20mg of PPY. After extraction, analytes were desorbed in ethyl acetate and analyzed using gas chromatography-flame ionization detection. The acid-base and other physico-chemical interactions with the analytes facilitated the adsorption of analytes, with good selectivity and reproducibility. Under the optimized extraction conditions, the method showed good linearity in the range of 0.001-0.3 microg ml(-1) of water sample (phosphate buffer 1.0 x 10(-3) M, pH 8.5), RSD=1.5-4.2% (n=4), and limits of detection 200-600 pg ml(-1). Each mu-SPE cartridge could be used for up to 20 extractions.
authors.affiliation: Pharmaceutical Chemistry Department, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah 6714967346, Iran. fahmadi@kums.ac.ir
authors.forename: Farhad
authors.initials: F
authors.lastname: Ahmadi
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Shahsavari
authors.forename: Mehdi
authors.initials: M
authors.lastname: Rahimi-Nasrabadi
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D010573:Pesticide Residues / Q000032:analysis*; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D010573:Pesticide Residues; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole