Anticarcinogenic compounds of olive oil and related biomarkers.
Olive oil, one of the oldest vegetable oils consumed without any refining, is associated with a reduced risk of a number of common cancers. Minor constituents of virgin olive oil have been suggested to be among the major chemopreventive components. A brief overview is presented of recent findings concerning the bioavailability of certain important olive oil minor components including efficient antioxidant polyphenols, the triterpene hydrocarbon squalene and beta-sitosterol, considered as putative nutritional biomarkers, in relation to the incidence of cancer.
Sotiroudis
Theodore G
TG
Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. tsotir@eie.gr
Kyrtopoulos
Soterios A
SA
D016588:Anticarcinogenic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D000975:Antioxidants / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001682:Biological Availability; D015415:Biomarkers / Q000097:blood / Q000652:urine; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*; D000069463:Olive Oil; D010636:Phenols / Q000008:administration & dosage / Q000493:pharmacokinetics; D010840:Phytosterols / Q000008:administration & dosage / Q000493:pharmacokinetics; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry*; D013185:Squalene / Q000008:administration & dosage / Q000493:pharmacokinetics
D016588:Anticarcinogenic Agents; D000975:Antioxidants; D015415:Biomarkers; D000069463:Olive Oil; D010636:Phenols; D010840:Phytosterols; D010938:Plant Oils; D013185:Squalene