title: UVA-Photosensitivity of cis-Diamminedichloro-Platinum(II)-Modified DNA.
abstract: cis-Diamminedichloroplatinum(II)-modified oligonucleotides contain-ing either a single intrastrand cross-link at the d(GpG) site or an interstrand cross-link at the d(GpC/GpC) site, were irradiated with 320 to 400-nm light. Upon irradiation, the adducts are photosensitive. Among the photo-induced reactions, the cleavage of the coordination bonds between platinum and the G residues in the interstrand cross-link is demonstrated.
authors.affiliation: Centre de Biophysique Moléculaire CNRS, 1A avenue dela Recherche Scientifique Orléans cedex 2 F-45071 France.
authors.forename: D
authors.initials: D
authors.lastname: Payet
authors.forename: M
authors.initials: M
authors.lastname: Leng