title: Accelerated tooth eruption in children with diabetes mellitus.
abstract: OBJECTIVE
  The objective of this study was to evaluate tooth eruption in 6- to 14-year-old children with diabetes mellitus.
  
  
  METHODS
  Tooth eruption status was assessed for 270 children with diabetes and 320 control children without diabetes. Data on important diabetes-related variables were collected. Analyses were performed using logistic regression models.
  
  
  RESULTS
  Children with diabetes exhibited accelerated tooth eruption in the late mixed dentition period (10-14 years of age) compared to healthy children. For both case patients and control subjects the odds of a tooth being in an advanced eruptive stage were significantly higher among girls than boys. There was also a trend associating gingival inflammation with expedited tooth eruption in both groups. No association was found between the odds of a tooth being in an advanced stage of eruption and hemoglobin A(1c) or duration of diabetes. Patients with higher body mass index percentile demonstrated statistically higher odds for accelerated tooth eruption, but the association was not clinically significant.
  
  
  CONCLUSIONS
  Children with diabetes exhibit accelerated tooth eruption. Future studies need to ascertain the role of such aberrations in dental development and complications such as malocclusion, impaired oral hygiene, and periodontal disease. The standards of care for children with diabetes should include screening and referral programs aimed at oral health promotion and disease prevention.
authors.affiliation: Division of Pediatric Dentistry, Columbia University College of Dental Medicine, P&S 3-454c, 630W 168th St, New York, NY 10032, USA. sl784@columbia.edu
authors.forename: Shantanu
authors.initials: S
authors.lastname: Lal
authors.forename: Bin
authors.initials: B
authors.lastname: Cheng
authors.forename: Selma
authors.initials: S
authors.lastname: Kaplan
authors.forename: Barney
authors.initials: B
authors.lastname: Softness
authors.forename: Ellen
authors.initials: E
authors.lastname: Greenberg
authors.forename: Robin S
authors.initials: RS
authors.lastname: Goland
authors.forename: Evanthia
authors.initials: E
authors.lastname: Lalla
authors.forename: Ira B
authors.initials: IB
authors.lastname: Lamster
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D003774:Dental Plaque Index; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005891:Gingivitis / Q000150:complications; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D014078:Tooth Eruption
chemical_list: D006442:Glycated Hemoglobin