[Effect of premix schedule on crystal formation of compound calcium phosphate cements].
OBJECTIVE
To investigate the effect of premix schedule on crystal formation of self-hardening calcium phosphate cements (CPC).


METHODS
CPC were prepared by mixing cement powders of tetracalcium phosphate(TTCP) with a cement liquid of phosphate acid saline solution. TTC-CPC, chitosan-CPC and chitosan-TTC-CPC were investigated with different premix schedules. The crystal formation was investigated by X-ray diffraction(XRD) and field scanning electron microscope(FSEM).


RESULTS
TTC and chitosan both affected the phase transition and crystal character in CPC. Chitosan, as organic additive, regulated the regular crystal formation and inhibited the phase transition of TTCP into OCP.


CONCLUSIONS
The premix schedule affects the crystal formation and phase transition, which may affect its biocompatibility and bioactivities in vivo.
Liu
Yan
Y
Department of Stomatology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Yao
Li-Yun
LY
Zhou
Bin
B
Mao
Jing
J
D001843:Bone Cements; D002130:Calcium Phosphates / Q000737:chemistry*; D048271:Chitosan; D003738:Dental Cements; D014961:X-Ray Diffraction
D001843:Bone Cements; D002130:Calcium Phosphates; D003738:Dental Cements; C485830:tetracalcium phosphate; D048271:Chitosan; C020243:calcium phosphate