Resting brain metabolic correlates of neuroticism and extraversion in young men.
Neuroticism and extraversion are two core dimensions of personality and are considered to be associated with emotional disorders. We investigated resting state brain metabolic correlates of neuroticism and extraversion using a positron emission tomography. Twenty healthy young men completed an F-flurodeoxyglucose-PET scan at rest and the Korean version of the revised Eysenck Personality Questionnaire. Neuroticism was negatively correlated with regional glucose metabolism in prefrontal regions including the medial prefrontal cortex. Extraversion was positively correlated with metabolism in the right putamen. These results suggest close associations between resting state brain activity in the prefrontal and striatal regions and specific personality traits and thus contribute to the understanding of the neurobiological bases of predisposition to psychiatric disorders.
Kim
Sang Hee
SH
Research Division of Human Life Sciences, Seoul National University, Seoul, Korea.
Hwang
Ji Hee
JH
Park
Hyun Soo
HS
Kim
Sang Eun
SE
D000328:Adult; D004734:Energy Metabolism / Q000502:physiology*; D005120:Extraversion, Psychological; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D009497:Neurotic Disorders / Q000000981:diagnostic imaging* / Q000378:metabolism*; D010551:Personality; D049268:Positron-Emission Tomography; D017397:Prefrontal Cortex / Q000000981:diagnostic imaging* / Q000378:metabolism; D011699:Putamen / Q000000981:diagnostic imaging* / Q000378:metabolism; D012146:Rest / Q000502:physiology
D019788:Fluorodeoxyglucose F18; D005947:Glucose