Can pentoxifylline improve the sperm motion and ICSI success in the primary ciliary dyskinesia?
Primary ciliary dyskinesia (PCD), previously known as immotile cilia syndrome, can cause respiratory and reproductive problems. Because of the impaired motion of microtubules the patients suffer upper respiratory tract problems. Infertility is an other issue of these patients. Several attempt have been proposed to bring back sperm motion and to improve intracytoplasmic sperm injection (ICSI) results. With our case we have described the management of a male infertility that causes from immotile cilia. The role of ICSI with incubated and activated ejaculatory sperm by pentoxifylline in the patient of PCD or as commonly named immotile cilia syndrome.
Yildirim
Gazi
G
Department of Obstetrics and Gynecology, Yeditepe University Hospital, Devlet Yolu, Ankara Cad. No: 102-104, Kozyatagi, Istanbul, Turkey. gaziyildirim@gmail.com
Ficicioglu
Cem
C
Akcin
Oya
O
Attar
Rukset
R
Tecellioglu
Nihan
N
Yencilek
Faruk
F
D000328:Adult; D002925:Ciliary Motility Disorders / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000628:therapy*; D008297:Male; D010431:Pentoxifylline / Q000008:administration & dosage*; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic; D013081:Sperm Motility / Q000187:drug effects*; D016896:Treatment Outcome
D010431:Pentoxifylline