Eight years of experience with molecular identification of human enteroviruses.
We have successfully typed 1,121 human enterovirus (HEV) isolates during the last 8 years by adapting partial VP1 sequencing to routine identification of HEV isolated from diverse clinical and environmental specimens. The isolates include 48 of the 59 traditional nonpoliovirus HEV serotypes and members of 8 newly discovered types, which would have remained untypeable by neutralization using the conventional cross-sectional pools of antisera.
Blomqvist
Soile
S
Department of Viral Diseases and Immunology, Enterovirus Laboratory, National Public Health Institute (KTL), Mannerheimintie 166, 00300 Helsinki, Finland. soile.blomqvist@ktl.fi
Paananen
Anja
A
Savolainen-Kopra
Carita
C
Hovi
Tapani
T
Roivainen
Merja
M
D016000:Cluster Analysis; D004770:Enterovirus / Q000145:classification* / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000821:virology*; D004783:Environmental Microbiology; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
D012367:RNA, Viral