title: Incidental carcinoma gall bladder during laparoscopic cholecystectomy for symptomatic gall stone disease.
abstract: BACKGROUND
  Carcinoma gall bladder (CaGB) is a disease with high mortality and is usually diagnosed as an incidental case among patients undergoing laparoscopic cholecystectomy (LC) for symptomatic gall stone disease.
  
  
  METHODS
  A total of 3205 LC done between January 2004 and August 2007 for symptomatic gall stone disease were retrospectively searched for incidental CaGB (detected on histopathology). None of these cases had preoperative suspicion of malignancy and their whole data was analyzed with special attention to preoperative and intraoperative findings which could raise suspicion of CaGB. In November 2007, patients were followed up telephonically about their present status of health.
  
  
  RESULTS
  Nineteen patients (14 female and 5 male) with incidental CaGB (incidence 0.59%) were detected. Mean age of the patients was 56 years. Only two of these patients had clinical jaundice and both had common bile duct (CBD) stones. The majority of the patients were in early pathological stages (pT) and none was in pT3 and pT4 stage. Seventeen patients could be followed up telephonically in November 2007 and of those 14 patients were alive at a mean follow-up duration of 21.2 months, with one of them having evidence of metastatic disease.
  
  
  CONCLUSIONS
  Gall bladder (GB) malignancy may be curable if diagnosed in early stages as an incidental finding and LC may not worsen the prognosis in such cases. In our series, incidental CaGB was detected in 0.59% patients undergoing LC. No association could be found between preoperative and intraoperative findings that could raise a suspicion of malignancy of gall bladder and so use of retrieval bag as a routine measure in cases with bile spillage may reduce the incidence of port-site metastasis.
authors.affiliation: Department of Minimal Access Surgery, ILS Multispeciality Clinic, DD-6, Sector - I, Salt Lake City, Kolkata, 700 064, India. omtantia@gmail.com
authors.forename: Om
authors.initials: O
authors.lastname: Tantia
authors.forename: Mayank
authors.initials: M
authors.lastname: Jain
authors.forename: Shashi
authors.initials: S
authors.lastname: Khanna
authors.forename: Bimalendu
authors.initials: B
authors.lastname: Sen
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects; D042883:Choledocholithiasis / Q000150:complications / Q000601:surgery; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery*; D055088:Early Detection of Cancer; D005260:Female; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D033162:Incidental Findings; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009366:Neoplasm Seeding; D009367:Neoplasm Staging; D015995:Prevalence