Microwave-enhanced sulphated zirconia and SZ/MCM-41 catalyzed regioselective synthesis of beta-amino alcohols under solvent-free conditions.
A solvent-free approach for the regioselective synthesis of beta-amino alcohols in shorter reaction times and higher yields, compared to conventional heating is described. It involves microwave (MW) exposure of undiluted reactants in the presence of sulphated zirconia (SZ) or sulphated zirconia over MCM-41 (SZM) as catalyst. Both acid materials can be easily recovered and reused.
Negrón-Silva
Guillermo
G
Departamento de Ciencias Básicas, UAM, Av. San Pablo No 180, C.P. 02200, México DF, México. gns@correo.azc.uam.mx
Hernández-Reyes
C Xochitl
CX
Angeles-Beltrán
Deyanira
D
Lomas-Romero
Leticia
L
González-Zamora
Eduardo
E
D000605:Amino Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002849:Chromatography, Gas; D005027:Ethylene Oxide / Q000737:chemistry; D008872:Microwaves; D012822:Silicon Dioxide / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*; D013237:Stereoisomerism; D013431:Sulfates / Q000737:chemistry*; D014961:X-Ray Diffraction; D015040:Zirconium / Q000737:chemistry*
D000605:Amino Alcohols; C509968:MCM-41; D012997:Solvents; D013431:Sulfates; D012822:Silicon Dioxide; D015040:Zirconium; D005027:Ethylene Oxide; C028541:zirconium oxide