Onychodystrophy and tumor-stage mycosis fungoides confined to a single digit: report of a case and review of nail findings in cutaneous T-cell lymphoma.
Mycosis fungoides is often considered one of the great disease imitators presenting with a wide variety of clinical manifestations. We present a case of tumor-stage mycosis fungoides involving a single digit clinically presenting with diffuse swelling of the digit and onychodystrophy. Histologic findings included a reticular dermal lymphocytic infiltrate with increased ratio of CD4:CD8 cells. The patient was treated with radiation resulting in complete resolution. Nail involvement with mycosis fungoides has been scarcely reported, but when present ranges from 20-nail dystrophy to yellow discoloration. The disease often involves most of the nails when present.
Grande-Sarpa
Hege
H
Department of Dermatology, University of Utah, Salt Lake City, Utah 84132, USA. Hege.Sarpa@hsc.utah.edu
Callis Duffin
Kristina P
KP
Florell
Scott R
SR
D000368:Aged; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology; D005385:Fingers; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000473:pathology* / Q000532:radiotherapy; D009260:Nail Diseases / Q000175:diagnosis* / Q000473:pathology* / Q000532:radiotherapy; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000532:radiotherapy