title: [Gastroesophageal reflux disease and pharyngolaryngeal reflux in children with chronic laryngeal pathology].
abstract: A prospective non-randomized trial was made to evaluate incidence of gastroesophageal reflux disease (GERD) and pharyngolaryngeal reflux (PLR) in children with chronic laryngeal pathology. A total of 46 children aged 6 to 15 years were examined including 16 patients with recurrent respiratory papillomatosis, 15 patients with acquired laryngotracheal scarry stenosis and 15 patients with vocal nodules and functional dysphonia. Combination of GERD with PLR is a factor of risk for scarry laryngostenosis in a child with recurrent respiratory papillomatosis. If it is impossible to perform 24-h pH-monitoring of the esophagus for detection of GERD or PLR in patients with chronic laryngeal pathology, antireflux therapy is prescribed empirically. It is necessary to establish significant diagnostic criteria of PLR.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Soldatskiĭ
authors.forename: E K
authors.initials: EK
authors.lastname: Onufrieva
authors.forename: i E
authors.initials: iE
authors.lastname: Pogosova
authors.forename: T G
authors.initials: TG
authors.lastname: Zaviktorina
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Strygina
authors.forename: S F
authors.initials: SF
authors.lastname: Gasparian
authors.forename: N V
authors.initials: NV
authors.lastname: Shchepin
authors.forename: A M
authors.initials: AM
authors.lastname: Steklov
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D007829:Laryngostenosis / Q000453:epidemiology*; D008297:Male; D008403:Mass Screening; D010212:Papilloma / Q000453:epidemiology*; D010614:Pharynx / Q000503:physiopathology*; D011446:Prospective Studies; D014827:Vocal Cords / Q000473:pathology