title: The National Emphysema Treatment Trial (NETT): a study in agency collaboration.
abstract: The National Emphysema Treatment Trial (NETT) was a multicenter, randomized, controlled clinical trial, comparing the efficacy of lung volume reduction surgery (LVRS) plus medical management with rehabilitation to medical management with rehabilitation in 1,218 patients with severe emphysema. The NETT was a precedent-setting collaborative effort of three government agencies: the Centers for Medicare and Medicaid Services (CMS); the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH); and the Agency for Healthcare Research and Quality (AHRQ). NETT provided Medicare beneficiaries with controlled access to a promising but unproven procedure, while scientifically valid data on the efficacy and costs were collected to guide future use, coverage decisions, and policy. NETT demonstrates that collaboration among federal agencies and among health plans, researchers, and providers can successfully fulfill their differing missions simultaneously and is a productive approach to evaluating new treatments of mutual interest.
authors.affiliation: Division of Lung Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7952, USA. gweinmann@nih.gov
authors.forename: Gail G
authors.initials: GG
authors.lastname: Weinmann
authors.forename: Yen-Pin
authors.initials: YP
authors.lastname: Chiang
authors.forename: Steven
authors.initials: S
authors.lastname: Sheingold
mesh_terms: D003299:Cooperative Behavior; D004059:Diffusion of Innovation; D006077:Government Agencies; D006801:Humans; D015337:Multicenter Studies as Topic; D010043:Outcome and Process Assessment, Health Care; D011013:Pneumonectomy; D011656:Pulmonary Emphysema / Q000175:diagnosis* / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic