title: Infertility and psychiatric morbidity.
abstract: OBJECTIVE
  To assess the relationship between psychiatric disorders and infertility.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Fertile and infertile volunteer couples in an academic research setting.
  
  
  METHODS
  Eighty-one infertile couples recruited from an infertility center before fertility treatment and 70 fertile controls recruited from an obstetrics and gynecology clinic.
  
  
  METHODS
  None.
  
  
  METHODS
  The presence of Axis 1 psychiatric disorders.
  
  
  RESULTS
  The occurrence of current psychiatric disorders was significantly higher among infertile subjects than among fertile controls, especially for adjustment disorder with mixed anxiety and depressed mood (16% vs. 2%) and for binge eating disorder (8% vs. 0).
  
  
  CONCLUSIONS
  Our data highlight that a percentage of infertile patients have already developed a psychiatric disorder at the time of their first contact with a specialized fertility service. Possible applications are discussed, including the recommendation that gynecologists screen for clinical or subclinical psychiatric disorders in infertility patients and offer treatment accordingly.
authors.affiliation: Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Tuscany, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Sbaragli
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Morgante
authors.forename: Arianna
authors.initials: A
authors.lastname: Goracci
authors.forename: Tara
authors.initials: T
authors.lastname: Hofkens
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Leo
authors.forename: Paolo
authors.initials: P
authors.lastname: Castrogiovanni
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D007246:Infertility / Q000453:epidemiology* / Q000523:psychology / Q000628:therapy; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D027724:Reproductive Techniques, Assisted