title: [Behçet's syndrome].
abstract: Behcet's syndrome (BS) is characterized by recurrent episodes of inflammatory manifestations, including oral and genital aphtosis, skin lesions, ocular attacks, arthritis, central nervous system and vascular manifestations (venous and arterial compartments). BS is more common in populations living in the ancient "silk road" from eastern Europe all the way to Japan. Several evidence suggest that both genetic and environmental factors are involved the pathogenesis. The association with the antigen HLA-B51 is observed with a highest frequency among patients of Middle Eastem countries and Japan. The diagnosis of BS is primarily established on clinical grounds in the absence of specific biological marker. The treatment is tailored according to the severity of clinical manifestations. The prognosis is more severe in young men.
authors.affiliation: Cem Gabay, Service de rhumatologie, HUG, 1211 Genève. Cem.Gabay@hcuge.ch
authors.forename: C
authors.initials: C
authors.lastname: Gabay
mesh_terms: D001528:Behcet Syndrome / Q000145:classification / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D006801:Humans; D011379:Prognosis