Report of two cases where sleep related eating behavior occurred with the extended-release formulation but not the immediate-release formulation of a sedative-hypnotic agent.
We report two cases in which amnestic sleep related eating disorder (SRED) occurred with extended-release zolpidem but not with the immediate-release formulation. These cases illustrate how even relatively small differences such as formulation can affect the likelihood of experiencing such events.
Chiang
Ambrose
A
Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA. ambrose.chiang@duke.edu
Krystal
Andrew
A
D000368:Aged; D000647:Amnesia / Q000139:chemically induced; D003692:Delayed-Action Preparations / Q000009:adverse effects; D020920:Dyssomnias / Q000139:chemically induced*; D001068:Feeding and Eating Disorders / Q000139:chemically induced*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D011725:Pyridines / Q000009:adverse effects*; D000077334:Zolpidem
D003692:Delayed-Action Preparations; D006993:Hypnotics and Sedatives; D011725:Pyridines; D000077334:Zolpidem