title: Evaluation of left ventricular systolic and diastolic function in patients with atrioventricular re-entrant tachycardia treated by radiofrequency current ablation.
abstract: Little is known about the long-term influence of radiofrequency current ablation (RFCA) on left ventricular (LV) systolic and diastolic function in patients with atrioventricular re-entrant tachycardia (AVRT).
  
  
  METHODS
  The study group consisted of 65 patients (33 M, mean age 39 +/- 11 y) with WPW syndrome and recurrent episodes of AVRT without any concomitant diseases. The control group consisted of 50 age-matched healthy volunteers. In both study and control groups transthorasic echocardiography (TTE) and Doppler were performed in order to assess LV systolic and diastolic function. In WPW patients TTE was followed by electrophysiology study and RFCA. TTE was repeated in 6-months time in the study group.
  
  
  RESULTS
  At 6-month follow-up a decrease in LV end-systolic diameters (1.77 +/- 0.22 vs. 1.67 +/- 0.22 cm/m2, P < 0.001) and volumes (20 +/- 6 vs. 17 +/- 5 ml, P < 0.001) and an increase in LV FS (33 +/- 6 vs. 37 +/- 5%, P < 0.001), EF (54 +/- 6 vs. 60 +/- 5%, P < 0.001), IVS (44 +/- 13 vs. 49 +/- 14%, P < 0.05) and LV PW thickening (58 +/- 19 vs. 62 +/- 16%, P < 0.05) was found. Doppler analysis revealed an increase in E wave (78 +/- 17 vs. 82 +/- 14 cm/s, P < 0.001), E/A ratio (1.14 +/- 0.37 vs. 1.33 +/- 0.24, P < 0.001) and a decrease in A wave (68 +/- 19 vs. 63 +/- 12 cm/s, P < 0.05), DT (219 +/- 33 vs. 180 +/- 20 ms, P < 0.001 ), IVRT (105 +/- 13 vs. 88 +/- 13 ms, P < 0.001), AR (26 +/- 8 vs. 18 +/- 12 cm/s, P < 0.001 ) and difference between duration of AR and A waves (5 +/- 24 vs. -12 +/- 21 ms, P < 0.001). No significant differences in regard to LV systolic and diastolic variables were found between patients and controls post RFCA.
  
  
  CONCLUSIONS
  RFCA of accessory pathway in patients with WPW syndrome and AVRT is associated with improvement of LV systolic and diastolic function.
authors.affiliation: Department of Cardiology, Medical University of Silesia in Katowice, Silesian Centre for Heart Disease, Zabrze, Poland. agataduszanska@op.pl
authors.forename: Agata
authors.initials: A
authors.lastname: Duszanska
authors.forename: Radosław
authors.initials: R
authors.lastname: Lenarczyk
authors.forename: Oskar
authors.initials: O
authors.lastname: Kowalski
authors.forename: Witold
authors.initials: W
authors.lastname: Streb
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kukulski
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Kalarus
mesh_terms: D000328:Adult; D003971:Diastole; D015150:Echocardiography, Doppler / Q000379:methods; D017548:Echocardiography, Transesophageal / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013599:Systole; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D013997:Time Factors; D016277:Ventricular Function, Left / Q000502:physiology*