title: NMR-guided fragment-based approach for the design of AAC(6')-Ib ligands.
authors.affiliation: Chimie Thérapeutique, UMR 8638, Université Paris Descartes, CNRS, 4 avenue de l'Observatoire, 75006 Paris, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lombès
authors.forename: Guillaume
authors.initials: G
authors.lastname: Bégis
authors.forename: Frédérique
authors.initials: F
authors.lastname: Maurice
authors.forename: Serge
authors.initials: S
authors.lastname: Turcaud
authors.forename: Thomas
authors.initials: T
authors.lastname: Lecourt
authors.forename: Frédéric
authors.initials: F
authors.lastname: Dardel
authors.forename: Laurent
authors.initials: L
authors.lastname: Micouin
mesh_terms: D000123:Acetyltransferases / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D000617:Aminoglycosides / Q000378:metabolism; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000378:metabolism* / Q000494:pharmacology; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D011485:Protein Binding
chemical_list: D000617:Aminoglycosides; D004791:Enzyme Inhibitors; D008024:Ligands; D000123:Acetyltransferases; C056532:aminoglycoside N(6')-acetyltransferase