title: Time course of eosinophilic myocarditis visualized by CMR.
abstract: We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressive heart failure. Endomyocardial biopsies were taken from the left ventricle because of a white blood cell count of 17000/mm3 with 41% eosinophils. Histological evaluation revealed endomyocardial eosinophilic infiltration and areas of myocyte necrosis. The patient was diagnosed with hypereosinophilic myocarditis due to idiopathic hypereosinophilic syndrome. CMR-studies at presentation and a follow-up study 3 weeks later showed diffuse subendocardial LGE in the whole left ventricle. Upon treatment with steroids, CMR-studies revealed marked reduction of subendocardial LGE after 3 months in parallel with further clinical improvement. This case therefore highlights the clinical importance of CMR to visualize the extent of endomyocardial involvement in the diagnosis and treatment of eosinophilic myocarditis.
authors.affiliation: Klinik und Poliklinik für Innere Medizin II, Klinikum der Universität, Regensburg, Germany. kurt.debl@klinik.uni-regensburg.de
authors.forename: Kurt
authors.initials: K
authors.lastname: Debl
authors.forename: Behrus
authors.initials: B
authors.lastname: Djavidani
authors.forename: Stefan
authors.initials: S
authors.lastname: Buchner
authors.forename: Florian
authors.initials: F
authors.lastname: Poschenrieder
authors.forename: Norbert
authors.initials: N
authors.lastname: Heinicke
authors.forename: Stefan
authors.initials: S
authors.lastname: Feuerbach
authors.forename: Günter
authors.initials: G
authors.lastname: Riegger
authors.forename: Andreas
authors.initials: A
authors.lastname: Luchner
mesh_terms: D001707:Biopsy, Needle; D004802:Eosinophilia; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D013997:Time Factors
chemical_list: D005938:Glucocorticoids