title: The efficacy of laparoscopic radical nephrectomy for renal cell cancer in the elderly: an oncological outcome analysis.
abstract: OBJECTIVE
  The efficacy and outcome of a laparoscopic radical nephrectomy (LRN) were retrospectively evaluated in patients aged >or=70 years, and the results were compared with those obtained from patients younger than 70 years undergoing laparoscopic surgery for the same indications.
  
  
  METHODS
  Data were collected for all patients undergoing an LRN for renal cell carcinoma between March 1999 and November 2006. A total of 129 LRN were performed. There were 34 elderly patients (>or=70 years) and 95 adult patients (<70 years). The two groups were compared for comorbidity, previous surgical history, operative time, estimated blood loss, tumor size, complications during and after surgery, time to oral intake/ambulation, hospital stay, overall survival and disease free survival rates.
  
  
  RESULTS
  In preoperative comorbid conditions, the number of patients with hypertension/ischemic heart disease in the elderly group was significantly greater than that in the adult group (p = 0.01). The elderly group had a mean operative time (247 min vs. 244 min) and blood loss (120 ml vs. 180 ml) similar to those in the adult group. In addition, the incidence of perioperative complications was not different between the two groups (intra-op: 2.9% vs. 5.3%/ post-op: 8.8% vs. 4.2%). All other variables before, during and after surgery were compatible between the two groups.
  
  
  CONCLUSIONS
  The efficacy and oncological outcome of laparoscopic surgery in elderly patients was as promising as those in their younger counterparts. Therefore, elderly patients should not be excluded from undergoing an LRN, even though they usually present with more comorbidities.
authors.affiliation: Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Harano
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Eto
authors.forename: Akira
authors.initials: A
authors.lastname: Yokomizo
authors.forename: Katsunori
authors.initials: K
authors.lastname: Tatsugami
authors.forename: Masumitsu
authors.initials: M
authors.lastname: Hamaguchi
authors.forename: Seiji
authors.initials: S
authors.lastname: Naito
mesh_terms: D000367:Age Factors; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome