Effect of confounding factors on blood pressure estimation using pulse arrival time.
Two confounding factors were selected and analyzed in blood pressure estimation using pulse arrival time (PAT) for each individual. The heart rate was used as the confounding factor for the cardiac cycle, and the duration from the maximum derivative point to the dicrotic peak (TDB) in the photoplethysmogram was used as another confounding factor representing arterial stiffness. By considering these factors with PAT in multiple regression analysis, the performance of blood pressure estimation is enhanced significantly in the diastolic phase as well as in the systolic phase. The reproducibility of this method was also validated with formerly obtained regression equations from the training set. The correlation between estimated and measured blood pressure decreased a little, but the validity was still maintained (r congruent with 0.8). This shows the value of the method in non-intrusive blood pressure estimation for individual patients and may be useful for various applications.
Kim
Jung Soo
JS
Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul, Korea. acamus@bmsil.snu.ac.kr
Kim
Ko Keun
KK
Baek
Hyun Jae
HJ
Park
Kwang Suk
KS
D000328:Adult; D000465:Algorithms; D016477:Artifacts; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000379:methods*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D008297:Male; D011673:Pulsatile Flow / Q000502:physiology*; D011674:Pulse; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity