title: Adverse reactions associated with respirator fit testing of healthcare workers in British Columbia, Canada: a review of compensation claim cases.
abstract: Thousands of healthcare workers in British Columbia are being fit tested for respirator use as a part of respiratory protection programs emanating from the SARS outbreak in 2003. The author reviews 8 claims submitted to the Workers' Compensation Board of British Columbia for adverse reactions related to denatonium benzoate fit testing. The adverse effects varied in severity. Most claims involved respiratory symptoms and 3 dermatitis or angioedema symptoms. One asthmatic required hospitalization for a severe asthmatic reaction. These cases indicate that there may be potentially significant health risks associated with denatonium benzoate-based fit testing at least for a small group of susceptible individuals. More systematic research is required.
authors.affiliation: Department of Medicine, University of British Columbia, Vancouver, Canada. syouakim@telusplanet.net
authors.forename: Sami
authors.initials: S
authors.lastname: Youakim
mesh_terms: D000062:Accidents, Occupational / Q000706:statistics & numerical data*; D000328:Adult; D001955:British Columbia; D004867:Equipment Design; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016272:Occupational Health; D000644:Quaternary Ammonium Compounds / Q000009:adverse effects* / Q000276:immunology; D012134:Respiratory Protective Devices; D012189:Retrospective Studies; D014942:Workers' Compensation
chemical_list: D000644:Quaternary Ammonium Compounds; C043414:denatonium