title: Cocaine abuse: dermatologic manifestations and therapeutic approaches.
abstract: Cocaine affects the cutaneous system and other organ systems. Cocaine use is associated with vasculitides, infectious complications, and numerous dermatologic conditions. It has been associated with formication (ie, tactile hallucinations of insects crawling underneath the skin), which leads to delusions of parasitosis and other psychosis-related dermatologic disorders. When a patient presents to a dermatology clinic with chronic skin lesions, a vague medical history, negative findings from previous evaluations, labile affect, and delusional behavior, drug screening should be performed to identify possible cocaine use.
authors.affiliation: Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA. brewer.jerry@mayo.edu
authors.forename: Jerry D
authors.initials: JD
authors.lastname: Brewer
authors.forename: Alexander
authors.initials: A
authors.lastname: Meves
authors.forename: J Michael
authors.initials: JM
authors.lastname: Bostwick
authors.forename: Kirsten Lyn
authors.initials: KL
authors.lastname: Hamacher
authors.forename: Mark R
authors.initials: MR
authors.lastname: Pittelkow
mesh_terms: D000328:Adult; D000818:Animals; D003042:Cocaine / Q000031:analogs & derivatives / Q000378:metabolism / Q000652:urine; D019970:Cocaine-Related Disorders / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D003702:Delusions / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010292:Paresthesia / Q000209:etiology*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D012876:Skin Diseases, Parasitic / Q000523:psychology; D015813:Substance Abuse Detection; D014076:Tooth Diseases / Q000209:etiology; D015431:Weight Loss
chemical_list: C005618:benzoylecgonine; D003042:Cocaine