title: MRI and FDG PET/CT findings in a case of probable Heidenhain variant Creutzfeldt-Jakob disease.
abstract: Creutzfeldt-Jakob disease (CJD) is a neurodegenerative disease caused by the accumulation of a pathogenic isoform of a prion protein in neurons that is responsible for subacute dementia. The Heidenhain variant is an atypical form of CJD in which visual signs are predominant. This is a report of the case of a 65-year-old man with probable CJD of the Heidenhain variant, with topographical concordance between findings on magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose (FDG) photopenic areas on positron emission tomography (PET)/computed tomography (CT) for cortical parietooccipital lesions.
authors.affiliation: Service de médecine nucléaire, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France. fredclare5@msn.com
authors.forename: F
authors.initials: F
authors.lastname: Clarençon
authors.forename: F
authors.initials: F
authors.lastname: Gutman
authors.forename: C
authors.initials: C
authors.lastname: Giannesini
authors.forename: A
authors.initials: A
authors.lastname: Pénicaud
authors.forename: D
authors.initials: D
authors.lastname: Galanaud
authors.forename: K
authors.initials: K
authors.lastname: Kerrou
authors.forename: B
authors.initials: B
authors.lastname: Marro
authors.forename: J-N
authors.initials: JN
authors.lastname: Talbot
mesh_terms: D000368:Aged; D003287:Contrast Media; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004569:Electroencephalography; D017809:Fatal Outcome; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18