title: A new method for investigation of the hair shaft: hard X-ray microscopy with a 90-nm spatial resolution.
abstract: Various methods have been used to investigate the hair shaft. In the ultrastructural hair field, scanning and transmission electron microscopies are widely used investigative methods, but they have some technical limitations. Recently, X-ray microscopes with sub-micron spatial resolution have emerged as useful instruments because they offer a unique opportunity to observe the interior of an undamaged sample in greater detail. In this report, we examined damaged hair shaft tips using hard X-ray microscopy with a 90 nm spatial resolution. The results of this study suggest that hard X-ray microscopy is an alternative investigative method for hair morphology studies.
authors.affiliation: Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, 162 Ilsan-dong, Wonju 220-710, Korea.
authors.forename: Soo-Young
authors.initials: SY
authors.lastname: Jeon
authors.forename: Ja Woong
authors.initials: JW
authors.lastname: Goo
authors.forename: Seung Phil
authors.initials: SP
authors.lastname: Hong
authors.forename: Tak Heon
authors.initials: TH
authors.lastname: Oh
authors.forename: Hwa Shik
authors.initials: HS
authors.lastname: Youn
authors.forename: Won-Soo
authors.initials: WS
authors.lastname: Lee
mesh_terms: D000328:Adult; D005260:Female; D006197:Hair / Q000473:pathology*; D006801:Humans; D008853:Microscopy / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D014965:X-Rays