title: Male choriocarcinoma with metastasis to the jejunum: a case report and review of the literature.
abstract: We report on a patient with male choriocarcinoma. The patient was a 31-year-old male patient with jejunal choriocarcinoma that metastasized from the mediastinum. He was admitted complaining of melena and severe anemia. Upper and lower gastrointestinal endosocopy was performed, but no source of bleeding was seen. Chest X-ray and CT revealed a mediastinal tumor 7 cm in size anterior to the arotic arch. Superior mesenteric arteriography showed irregularities and macular opacity in the jejunal artery. An emergency laparatomy was performed because of massive gastrointestinal bleeding. A jejunal tumor approximately 4 cm in size was resected and numerous metastases were observed in the liver and mesentery. Histopathological examination showed metastatic jejunal choriocarcinoma. Gynecomastia was not present and the testes were normal. Serum beta-human chorionic gonadotropin (HCG) was at an abnormally high level of 4,396 ng/mL. Because of metastases to the brain and invasion to the trachea, he died on postoperative day 20. We report this rare case of a male patient with metastases of choriocarcinoma to the gastrointestinal tract from the mediastinum, together with a review of the literature.
authors.affiliation: Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School, Japan. kimiyoko@nms.ac.jp
authors.forename: Kimiyoshi
authors.initials: K
authors.lastname: Yokoi
authors.forename: Noritake
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Furukawa
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ishikawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Seya
authors.forename: Koji
authors.initials: K
authors.lastname: Horiba
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Kanazawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamada
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Ohaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Tajiri
mesh_terms: D000328:Adult; D031954:Choriocarcinoma, Non-gestational / Q000473:pathology* / Q000556:secondary*; D006801:Humans; D007580:Jejunal Neoplasms / Q000556:secondary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*