title: Improved procedure for the synthesis of enamine N-oxides.
abstract: An improved procedure for the preparation of enamine N-oxides involving aminolysis of epoxides, chlorination, N-oxidation, and dehydrochlorination is described. Although isolated beta-chloroamine N-oxides are prone to rearrangements when isolated, these side reactions can be slowed by the presence of stabilizing organic acids. The scope and limitations of this strategy are discussed.
authors.affiliation: School of Chemistry, The University of Nottingham, Nottingham, United Kingdom.
authors.forename: David
authors.initials: D
authors.lastname: Bernier
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Blake
authors.forename: Simon
authors.initials: S
authors.lastname: Woodward