Normal modes and essential dynamics.
Normal mode analysis and essential dynamics analysis are powerful methods used for the analysis of collective motions in biomolecules. Their application has led to an appreciation of the importance of protein dynamics in function and the relationship between structure and dynamical behavior. In this chapter, the methods and their implementation are introduced and recent developments such as elastic networks and advanced sampling techniques are described.
Hayward
Steven
S
School of Computing Sciences and School of Biological Sciences, University of East Anglia, Norwich, UK.
de Groot
Bert L
BL
D000465:Algorithms; D001665:Binding Sites; D003198:Computer Simulation; D008958:Models, Molecular; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry
D011506:Proteins