title: Inactivation of avian influenza virus using common detergents and chemicals.
abstract: Six disinfectant chemicals were tested individually for effectiveness against low pathogenic avian influenza virus (LPAIV) A/H7N2/Chick/MinhMa/04. The tested agents included acetic acid (C2H4O2), citric acid (C6H8O7), calcium hypochlorite (Ca(ClO)2), sodium hypochlorite (NaOCl), a powdered laundry detergent with peroxygen (bleach), and a commercially available iodine/acid disinfectant. Four of the six chemicals, including acetic acid (5%), citric acid (1% and 3%), calcium hypochlorite (750 ppm), and sodium hypochlorite (750 ppm) effectively inactivated LPAIV on hard and nonporous surfaces. The conventional laundry detergent was tested at multiple concentrations and found to be suitable for inactivating LPAIV on hard and nonporous surfaces at 6 g/L. Only citric acid and commercially available iodine/acid disinfectant were found to be effective at inactivating LPAIV on both porous and nonporous surfaces.
authors.affiliation: Department of Bioresources Engineering, University of Delaware, 264 Townsend Hall, Newark, DE 19716, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Lombardi
authors.forename: B S
authors.initials: BS
authors.lastname: Ladman
authors.forename: R L
authors.initials: RL
authors.lastname: Alphin
authors.forename: E R
authors.initials: ER
authors.lastname: Benson
mesh_terms: D000818:Animals; D002642:Chick Embryo; D003252:Construction Materials / Q000821:virology; D003902:Detergents / Q000494:pharmacology*; D004202:Disinfectants / Q000494:pharmacology*; D004783:Environmental Microbiology; D006799:Housing, Animal; D009980:Influenza A virus / Q000187:drug effects*; D038301:Virus Inactivation / Q000187:drug effects*
chemical_list: D003902:Detergents; D004202:Disinfectants