title: Sternal closure techniques and postoperative sternal wound complications in elderly patients.
abstract: OBJECTIVE
  Postoperative sternal wound complications (PSWC) including deep sternal wound infection (DSWI) and sternal dehiscence (SD) cause significant morbidity and mortality. Elderly patients with several risk factors are particularly prone to suffer PSWC.
  
  
  METHODS
  We present (I) a subset of 86 patients, all aged > or =75 years out of 339 cardiac surgery patients prospectively randomised to receive either conventional sternal closure or a Robicsek type closure. Primary end-points were SD and DSWI; secondary end-points included a composite of clinical parameters; (II) we retrospectively assessed data of 54/5273 patients with mediastinitis regarding the influence of advanced age. In addition, we report an epidemiological overview of different sternal closure techniques.
  
  
  RESULTS
  (I) The Robicsek technique showed an impact on SD and DSWI, and several secondary end-points: ventilator support (p=0.03), postoperative blood loss (p=0.04), and chest pain >3 days (p=0.04). (II) A total of 54/5273 (1.02%) patients developed postoperative mediastinitis. Twelve out of 54 (22%) patients died within 6 months of the initial operation. Predictors of mortality were insulin-dependent diabetes mellitus (p=0.05), renal insufficiency (p=0.01), delayed sternal closure (p=0.05), ICU-stay >10 days (p=0.01), and methicillin-resistant Staphylococcus aureus (p=0.03) or fungal infection (p=0.02).
  
  
  CONCLUSIONS
  No statistical difference in sternal dehiscence or mediastinitis was found irrespective of whether the bilateral and longitudinal parasternal closure or the conventional peri/trans-sternal wiring technique was used, but there was an obvious, positive influence on sternal dehiscence, deep sternal wound infection, and clinical parameters. However, the study population is relatively small.
authors.affiliation: University of Würzburg, Department of Cardiac and Thoracic Surgery, Würzburg, Germany. Schimmer_c@klinik.uni-wuerzburg.de <Schimmer_c@klinik.uni-wuerzburg.de>
authors.forename: Christoph
authors.initials: C
authors.lastname: Schimmer
authors.forename: Sebastian-Patrick
authors.initials: SP
authors.lastname: Sommer
authors.forename: Marc
authors.initials: M
authors.lastname: Bensch
authors.forename: Thomas
authors.initials: T
authors.lastname: Bohrer
authors.forename: Ivan
authors.initials: I
authors.lastname: Aleksic
authors.forename: Rainer
authors.initials: R
authors.lastname: Leyh
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001864:Bone Wires; D006348:Cardiac Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000209:etiology* / Q000517:prevention & control; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D013249:Sternum / Q000601:surgery*; D013529:Surgical Wound Dehiscence / Q000209:etiology* / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000209:etiology* / Q000517:prevention & control; D013536:Suture Techniques