title: [Depression and psoriasis].
abstract: Psychiatric co-morbidity is very frequently associated with psoriasis. Depression is observed in numerous patients with psoriasis. Early detection and treatment are very important. There is a vicious circle psoriasis- alteration of quality of life- depression, but psoriasis improvement is not always followed by an improvement of depression. A contrario, it is obvious that a depressive patient has a bad observance of treatment. Links between psoriasis and depression are not only psychopathological. Biological factors, such as increase of blood amounts of substance P and TNF or decrease of serotonine could also explain this association.
authors.affiliation: Service de Psychiatrie, CHU Brest, 5 Avenue Foch, 29200 Brest, France.
authors.forename: K
authors.initials: K
authors.lastname: Bouguéon
authors.forename: L
authors.initials: L
authors.lastname: Misery
mesh_terms: D001714:Bipolar Disorder / Q000453:epidemiology; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology*; D006801:Humans; D011565:Psoriasis / Q000453:epidemiology* / Q000523:psychology*; D011788:Quality of Life