[QuantiFERON: an early diagnostic tool for cerebral tuberculosis].
Two cases (a 33-year-old woman and a 34-year-old man) were diagnosed as having cerebral tuberculosis. Case 1 was tuberculoma with miliary tuberculosis complicating cranial nerve palsies, and case 2 was tuberculous meningitis. Early diagnosis was difficult, because smear and PCR were negative. Culture was finally positive after several weeks. QuantiFERON were positive prior to the culture results in both cases. This reaction suggested tuberculous infection. QuantiFERON is useful for diagnosing cerebral tuberculosis at an early stage.
Iguchi
Masahiro
M
Department of Neurology, Tokyo Women's Medical University School of Medicine.
Maruyama
Kenji
K
Tsutsumi
Yukiko
Y
Uchiyama
Shinichiro
S
Iwata
Makoto
M
D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood; D008297:Male; D011993:Recombinant Fusion Proteins; D014375:Tuberculoma / Q000175:diagnosis; D020306:Tuberculosis, Central Nervous System / Q000175:diagnosis*; D014390:Tuberculosis, Meningeal / Q000175:diagnosis; D014391:Tuberculosis, Miliary / Q000175:diagnosis
C505464:ESAT-6-CFP10 fusion protein; D011993:Recombinant Fusion Proteins; D007371:Interferon-gamma