The first documented case of brucellosis manifested with pancytopenia and capillary leak syndrome.
Hematological complications have been frequently associated with acute brucellosis, but pancytopenia is less frequently seen. Also, capillary leak syndrome has been rarely reported in the literature. In this report, we present a case of brucellosis with pancytopenia leading to capillary leak syndrome. A 21-year-old man was admitted to hospital with complaints of a one-month history of weakness, sweats, and fever and he had hepatosplenomegaly and edema over the pretibial areas. Hemogram revealed pancytopenia and biochemical tests revealed moderate hypoalbuminemia, elevations of lactate dehydrogenase and aspartate aminotransferase. He was diagnosed as brucellosis and capillary leak syndrome. He was given doxycycline and rifampicin. The patient's symptoms were resolved after treatment.
Erkurt
Mehmet Ali
MA
Department of Hematology, Gulhane Military Medical Academy, Ankara, Turkey. erkurtali@hotmail.com
Sari
Ismail
I
Gül
Hanefi Cem
HC
Coskun
Omer
O
Eyigün
Can Polat
CP
Beyan
Cengiz
C
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000150:complications* / Q000188:drug therapy; D019559:Capillary Leak Syndrome / Q000188:drug therapy / Q000209:etiology*; D004318:Doxycycline / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D012293:Rifampin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004318:Doxycycline; D012293:Rifampin