Central nervous system regulation of energy metabolism: ghrelin versus leptin.
In this brief review, we introduce some major themes in the regulation of energy, lipid, and glucose metabolism by the central nervous system (CNS). Rather than comprehensively discussing the field, we instead will discuss some of the key findings made regarding the interaction of the hormones ghrelin and leptin with the CNS.
Nogueiras
Ruben
R
Obesity Research Center, Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA.
Tschöp
Matthias H
MH
Zigman
Jeffrey M
JM
D000368:Aged; D001066:Appetite; D001111:Arcuate Nucleus of Hypothalamus / Q000502:physiology; D001835:Body Weight / Q000502:physiology*; D002490:Central Nervous System / Q000502:physiology* / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000209:etiology / Q000503:physiopathology; D004734:Energy Metabolism; D054439:Ghrelin / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D020738:Leptin / Q000502:physiology*; D009765:Obesity / Q000209:etiology / Q000503:physiopathology
D054439:Ghrelin; D020738:Leptin; D005947:Glucose