Total synthesis of (-)-dysithiazolamide.
The tetrachlorinated natural product (-)-dysithiazolamide was synthesized from l-glutamic acid in a convergent way, confirming the previously proposed (2S,4S,6S,8S) absolute stereochemistry.
Ardá
Ana
A
Departamento de Química Fundamental, Facultade de Ciencias, Campus da Zapateira, Universidade da Coruña, Coruña, Spain.
G Soengas
Raquel
R
Nieto
M Isabel
MI
Jiménez
Carlos
C
Rodríguez
Jaime
J
D018698:Glutamic Acid / Q000737:chemistry; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
C530329:(-)-dysithiazolamide; D013844:Thiazoles; D018698:Glutamic Acid