title: LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation.
abstract: Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.
authors.affiliation: Centre for Molecular Nanometrology, WestCHEM, Glasgow, UK.
authors.forename: Fiona
authors.initials: F
authors.lastname: McKenzie
authors.forename: Karen
authors.initials: K
authors.lastname: Faulds
authors.forename: Duncan
authors.initials: D
authors.lastname: Graham
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000032:analysis* / Q000737:chemistry / Q000235:genetics; D015342:DNA Probes / Q000737:chemistry* / Q000235:genetics; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D019001:Nitric Oxide Synthase / Q000235:genetics; D009841:Oligonucleotides / Q000737:chemistry*
chemical_list: D015342:DNA Probes; D009841:Oligonucleotides; C477371:locked nucleic acid; C051802:triplex DNA; D006046:Gold; D004247:DNA; D019001:Nitric Oxide Synthase