Skin tissue engineering for tissue repair and regeneration.
Tissue-engineered skin is a significant advance in the field of wound healing. It has mainly been developed because of limitations associated with the use of autografts and allografts where the donor site suffers from pain, infection, and scarring. Recently, tissue-engineered skin replacements have been finding widespread application, especially in the case of burns, where the major limiting factor is the availability of autologous skin. The development of a bioartificial skin facilitates the treatment of patients with deep burns and various skin-related disorders. The present review gives a comprehensive overview of the developments and future prospects of scaffolds as skin substitutes for tissue repair and regeneration.
Priya
S Geetha
SG
Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, India.
Jungvid
Hans
H
Kumar
Ashok
A
D000818:Animals; D021522:Bioartificial Organs; D001672:Biocompatible Materials; D001698:Biomedical Engineering / Q000379:methods*; D006801:Humans; D015603:Keratinocytes / Q000166:cytology; D051379:Mice; D016513:Mice, SCID; D008954:Models, Biological; D012038:Regeneration; D012867:Skin / Q000473:pathology*; D016038:Skin Transplantation / Q000379:methods*; D017768:Skin, Artificial; D023822:Tissue Engineering / Q000379:methods*; D014945:Wound Healing
D001672:Biocompatible Materials