title: Subcutaneous immunoglobulin administration: an alternative to intravenous infusion as adjuvant treatment for dermatomyositis?
abstract: Monthly high-dose intravenous administration of human polyclonal immunoglobulins (IVIG) has been shown to be effective as an adjuvant treatment for dermatomyositis. We report a patient with dermatomyositis treated with high doses of immunoglobulins by subcutaneous infusion (SCIG). SCIG was used because of the lack of peripheral and central vein access to continue effective IVIG therapy. The treatment was administered at home, was well tolerated, and was associated to the stabilization of the disease after a 1-year follow-up. Thus, our report suggests that SCIG could be an alternative to IVIG in the treatment of dermatomyositis.
authors.affiliation: Department of Internal Medicine, CHU Conception, AP-HM, 13385, Marseille Cedex, France. nicolas.schleinitz@ap-hm.fr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Schleinitz
authors.forename: Estelle
authors.initials: E
authors.lastname: Jean
authors.forename: Lucas
authors.initials: L
authors.lastname: Benarous
authors.forename: Karin
authors.initials: K
authors.lastname: Mazodier
authors.forename: Dominique
authors.initials: D
authors.lastname: Figarella-Branger
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Bernit
authors.forename: Véronique
authors.initials: V
authors.lastname: Veit
authors.forename: Gilles
authors.initials: G
authors.lastname: Kaplanski
authors.forename: Jean-Robert
authors.initials: JR
authors.lastname: Harle
mesh_terms: D003882:Dermatomyositis / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D055104:Infusions, Subcutaneous; D008875:Middle Aged
chemical_list: D016756:Immunoglobulins, Intravenous