[A case of anti-LKM 1 positive autoimmune hepatitis accompanied by systemic lupus erythematosus].
Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti-LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis.
Choi
Dae Han
DH
Department of Internal Medicine, Kwang Myung SungAe Hospital, Gwangmyeong, Korea.
Kim
Hae Kyung
HK
Park
Tae Il
TI
John
Byung Min
BM
Kang
Sung Hwan
SH
Lee
Yoon Serk
YS
Kim
Tae Hyun
TH
Lee
Uh Joo
UJ
Lee
Tae Seung
TS
Yoon
Gwi Ok
GO
D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D004452:Echocardiography; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008099:Liver / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D055815:Young Adult
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; C060729:anti-liver kidney microsome antibody