Sweet's syndrome associated with multiple myeloma.
BACKGROUND
Sweet's syndrome (SS) is an acute febrile neutrophilic dermatosis. It may be paraneoplastic in 10 to 20% of cases. Association with multiple myeloma (MM) is uncommon.


METHODS
We report on a 73-year-old woman that developed SS 2 months after being diagnosed with IgG MM. Cutaneous lesions improved rapidly after chemotherapy for the MM. No recurrence of SS has taken place during the subsequent 2 years.


CONCLUSIONS
Association of SS with MM has been rarely described in the literature. Only 14 cases of SS with MM have been reported. The secretory status of the MM may influence the occurrence of SS. SS seems to be related to IgG MM. Patients with IgG MM may have more risk of developing SS than those with other secretory types.
Belhadjali
Hichem
H
Department of Dermatology, Fattouma Bourguiba Hospital, Monastir 5000, Tunisia. hichem@prontomail.com
Chaabane
Sami
S
Njim
Leïla
L
Youssef
Monia
M
Zakhama
Abdelfattah
A
Zili
Jamel
J
D000368:Aged; D005260:Female; D006801:Humans; D009101:Multiple Myeloma / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D016463:Sweet Syndrome / Q000209:etiology*