[Statins in coronary patients: a solved issue?].
Statin prescription in patients with coronary artery disease is justified by numerous randomized controlled trials. These trials were conducted in various clinical conditions such as acute coronary syndrome and stable angina. Statin therapy was nearly always associated with better clinical outcomes. These benefits were highly significant in stable coronary patients with hypercholesterolemia and less striking in the first days of acute coronary syndrome. However, in patients with or without acute coronary syndrome, long-term prognosis was favorably influenced in patients on statin therapy. In patients with coronary artery disease, physicians must prescribe a well-tolerated statin as soon as possible, and verify long-term compliance in every patient.
Ferrières
J
J
Service de Cardiologie B, CHU Rangueil, TSA 50032, 31059 Toulouse cedex 9, France. jean.ferrieres@cict.fr
D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000188:drug therapy* / Q000503:physiopathology; D050171:Dyslipidemias / Q000503:physiopathology; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors