[Radiotherapy and chemotherapy for oncological diseases--unappreciated risk factors for coronary artery disease? Acute coronary syndrome in 3 women after radiotherapy and chemotherapy--case reports].
Chest irradiation and chemotherapy may lead to precocious coronary artery disease due to accelerated atherosclerosis or fibrointimal hyperplasia. Three cases of women (43, 50, and 53 years old) without typical risk factors for cardiac disease admitted to hospital due to acute coronary syndrome are described. Two of them had received chest irradiation and chemotherapy for Hodgkin's disease in the past and the third had been treated with chemotherapy for breast cancer. They underwent emergency coronary angiography myocardial revascularisation with success (PCI treatment and CABG). Continued longitudinal screening of patients exposed to radiation and chemotherapy is needed to provide the best cardiology care.
Wozakowska-Kapłon
Beata
B
I Oddział Kardiologii, Swietokrzyskie Centrum Kardiologii, Wojewódzki Szpital Zespolony, Kielce. bw.kaplon@poczta.onet.pl
Szymczyk
Rafał
R
Buda
Stanisław
S
Biskup
Piotr
P
D054058:Acute Coronary Syndrome / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000209:etiology*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D017023:Coronary Angiography; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects; D012307:Risk Factors; D016896:Treatment Outcome