title: Biorejuvenation: theory and practice.
abstract: The aim of mesotherapy for skin rejuvenation is to increase the biosynthetic capacity of fibroblasts, inducing the reconstruction of an optimal physiologic environment, the enhancement of cell activity, and the synthesis of collagen, elastin, and hyaluronic acid. The desired final effect is a firm, bright, and moisturized skin, and the injection in the superficial dermis of suitable products--perfectly biocompatible and totally absorbable--can achieve these results. In addition to a daily sunscreen application and nonsmoking, mesotherapy is another antiaging strategy helping to maintain a globally firm and bright skin, protecting it from the environmental contributors to aging.
authors.affiliation: Department of Dermatology, University of Bologna, 40138 Bologna, Italy. matildeiorizzo@hotmail.com
authors.forename: Matilde
authors.initials: M
authors.lastname: Iorizzo
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: De Padova
authors.forename: Antonella
authors.initials: A
authors.lastname: Tosti
mesh_terms: D001673:Biodegradation, Environmental; D003357:Cosmetic Techniques / Q000009:adverse effects; D003879:Dermatologic Agents / Q000008:administration & dosage*; D004549:Elastin; D005145:Face; D005347:Fibroblasts; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D012060:Rejuvenation; D012867:Skin; D015595:Skin Aging / Q000187:drug effects*; D014815:Vitamins / Q000008:administration & dosage*
chemical_list: D003879:Dermatologic Agents; D014815:Vitamins; D006820:Hyaluronic Acid; D004549:Elastin