title: In vitro biocompatibility of equal channel angular processed (ECAP) titanium.
abstract: This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. This could be attributed to the increased surface energy and grain boundary energy and possibly the presence of a large number of nano-size conical groove-like structures (at triple point junctions of grain boundaries on the surface) in the ECAP Ti specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy.
authors.affiliation: Department of Information and Electronic Materials Engineering, Paichai University, Daejeon 302-735, Korea. tnkim@mail.pcu.ac.kr
authors.forename: Taik Nam
authors.initials: TN
authors.lastname: Kim
authors.forename: A
authors.initials: A
authors.lastname: Balakrishnan
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: W S
authors.initials: WS
authors.lastname: Kim
authors.forename: K
authors.initials: K
authors.lastname: Smetana
authors.forename: J K
authors.initials: JK
authors.lastname: Park
authors.forename: B B
authors.initials: BB
authors.lastname: Panigrahi
mesh_terms: D016475:3T3 Cells; D000497:Alloys; D000818:Animals; D001672:Biocompatible Materials / Q000008:administration & dosage* / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects*; D008422:Materials Testing; D051379:Mice; D013499:Surface Properties; D014025:Titanium / Q000008:administration & dosage* / Q000737:chemistry*
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; C031462:titanium alloy (TiAl6V4); D014025:Titanium