title: Ossifying fibromyxoid tumor of oral cavity.
abstract: Ossifying fibromyxoid tumor is a rare tumor of mesenchymal origin with varied presentation at different sites including head and neck. Clinically these are slow growing lesions and patients have a variable age at presentation. A 14 years old girl presented with a slowly enlarging gingival swelling, which on radiological examination showed increased rarefaction in the mandible with a provisional diagnosis of an inflammatory lesion. Microscopically, the tumor had spindle to oval shaped cells in a fibromyxoid background with a peripheral shell of lamellar bone. Histological diagnosis of ossifying fibromyxoid tumor was made after immunohistochemical stains for vimentin and S-100 protein. Recurrence, metastasis and histologically increased mitotic count are indicative of atypical or malignant ossifying fibromyxoid tumors.
authors.affiliation: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi. ashrafof@gmail.com
authors.forename: Muhammad Ashraf
authors.initials: MA
authors.lastname: Sharif
authors.forename: Sajid
authors.initials: S
authors.lastname: Mushtaq
authors.forename: Nadira
authors.initials: N
authors.lastname: Mamoon
authors.forename: Muhammad Tahir
authors.initials: MT
authors.lastname: Khadim
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D018214:Fibroma, Ossifying / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D009418:S100 Proteins; D014746:Vimentin