title: Lyme disease: laboratory issues.
abstract: This article describes the laboratory modalities available to confirm the diagnosis of Lyme borreliosis. Use and limitations of these methods are discussed. Current guidelines for the use of recommended serologic methods and discussion of newer methods also are provided.
authors.affiliation: Department of Pathology, Medicine, and Microbiology, New York Medical College, Valhalla, NY 10595, USA. m_aguero-rosenfeld@nymc.edu
authors.forename: Maria E
authors.initials: ME
authors.lastname: Aguero-Rosenfeld
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial / Q000032:analysis*; D025065:Borrelia burgdorferi / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D016056:Immunodominant Epitopes / Q000032:analysis; D008193:Lyme Disease / Q000175:diagnosis*; D016133:Polymerase Chain Reaction; D012867:Skin / Q000382:microbiology; D013582:Synovial Fluid / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D004269:DNA, Bacterial; D016056:Immunodominant Epitopes