One new triterpenoid from biotransformation product of glycyrrhizic acid.
A new triterpenoid compound (1) and a known compound (2) were isolated from the product of biotransformation of glycyrrhizic acid by Aspergillus niger. On the basis of the 1D and 2D NMR ((1)H-(1)H COSY, HSQC, HMBC and NOESY) and MS spectrometry, their structures were established as 7beta, 15alpha-dihydroxy-3,11-dioxo-oleana-12-en-30-oic acid (1) and 15alpha-hydroxy-3,11-dione-oleana-12-en-30-oic acid (2), respectively.
Kang
Li-Ping
LP
Beijing Institute of Radiation Medicine, Beijing, China.
Zhang
Jie
J
Yu
He-Shui
HS
Huang
Hong-Zhi
HZ
Wang
Yong-Ze
YZ
Ma
Bai-Ping
BP
D001234:Aspergillus niger / Q000378:metabolism; D001711:Biotransformation; D006035:Glycyrrhiza / Q000737:chemistry; D019695:Glycyrrhizic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D014315:Triterpenes; D019695:Glycyrrhizic Acid