title: Anhedonia and amotivation in psychiatric outpatients with fully remitted stimulant use disorder.
abstract: This study evaluated whether psychiatric outpatients with a past stimulant use disorder in full remission for >/= 2 months (STIM+, n = 204) and those with no history of stimulant use disorder (STIM-, n = 2070) differed in the prevalence of current anhedonia and amotivation. Results showed that a significantly greater proportion of STIM+ participants reported anhedonia and amotivation than STIM- participants. The relation between stimulant use disorder history and anhedonia remained robust after controlling for other relevant clinical and demographic factors. These findings suggest that anhedonia may be a preexisting risk factor or protracted effect of stimulant misuse.
authors.affiliation: Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.
authors.forename: Adam M
authors.initials: AM
authors.lastname: Leventhal
authors.forename: Christopher W
authors.initials: CW
authors.lastname: Kahler
authors.forename: Lara A
authors.initials: LA
authors.lastname: Ray
authors.forename: Kristen
authors.initials: K
authors.lastname: Stone
authors.forename: Diane
authors.initials: D
authors.lastname: Young
authors.forename: Iwona
authors.initials: I
authors.lastname: Chelminski
authors.forename: Mark
authors.initials: M
authors.lastname: Zimmerman
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects; D000342:Affective Symptoms / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D000553:Ambulatory Care; D000661:Amphetamine / Q000009:adverse effects*; D019969:Amphetamine-Related Disorders / Q000534:rehabilitation*; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000534:rehabilitation*; D015897:Comorbidity; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000523:psychology / Q000534:rehabilitation*; D008694:Methamphetamine / Q000009:adverse effects*; D008875:Middle Aged; D009042:Motivation; D012237:Rhode Island; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis* / Q000523:psychology
chemical_list: D000697:Central Nervous System Stimulants; D008694:Methamphetamine; D000661:Amphetamine; D003042:Cocaine