title: Vaginal cuff dehiscence after hysterectomy in a woman with systemic lupus erythematosus: a case report.
abstract: BACKGROUND
  Vaginal cuff dehiscence is an uncommon but serious complication of hysterectomy. It has not previously been described in the setting of systemic lupus erythematosus (SLE) and total laparoscopic hysterectomy (TLH).
  
  
  METHODS
  A 43-year-old woman with SLE presented to the emergency department >7 weeks after TLH with severe abdominal pain resulting from a postoperative intercourse attempt. Examination under anesthesia revealed complete separation of the anterior and posterior vaginal cuff edges.
  
  
  CONCLUSIONS
  A patient's medical profile, including comorbidities that affect wound healing, plays a role in vaginal cuff integrity after hysterectomy. For patients with SLE undergoing TLH, temporarily stopping immunosuppressive medications for several weeks preoperatively and postoperatively and allowing prolonged recovery with pelvic rest may improve postoperative outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Saint Joseph Mercy Hospital, Ann Arbor, Michigan, USA. purakjc@trinity-health.org
authors.forename: Joyce
authors.initials: J
authors.lastname: Purakal
authors.forename: Gayle
authors.initials: G
authors.lastname: Moyer
authors.forename: William
authors.initials: W
authors.lastname: Burke
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000009:adverse effects; D010535:Laparoscopy / Q000009:adverse effects; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives; D012146:Rest; D013529:Surgical Wound Dehiscence / Q000209:etiology*; D014623:Vaginal Diseases / Q000209:etiology*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid