Extreme hypertriglyceridemia following intravenous heparin infusion.
We report a case of unexpected extreme hypertriglyceridemia in a 32 year old man following 5 days of intravenous heparin infusion. We believe the cause of the elevation is mainly due to a temporary depletion of lipoprotein lipase caused by heparin. To the best of our knowledge, this is the first case report of such an extreme elevation in triglycerides following prolonged intravenous heparin infusion. The clinical history and details of the suggested mechanism of the hypertriglyceridemia are discussed in this case report.
Al Riyami
Nafila B
NB
Department of Medical Biochemistry, University of British Columbia, St Paul's Hospital, Vancouver, Canada V6Z 1Y6. nafilariyami@gmail.com
Frohlich
Jiri
J
D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D015228:Hypertriglyceridemia / Q000139:chemically induced*; D007262:Infusions, Intravenous; D008071:Lipoprotein Lipase / Q000097:blood / Q000172:deficiency; D008297:Male; D020246:Venous Thrombosis / Q000188:drug therapy
D006493:Heparin; D008071:Lipoprotein Lipase