Some pharmacological properties of immunotropic preparation from porcine skin.
We studied pharmacological properties of immunotropic preparation from porcine skin (skin resorption effect and acute and chronic toxicity). It was demonstrated that the preparation did not damage the skin during evaluation of skin-resorption effect; evaluation of acute and chronic toxicity revealed no changes in the general state of experimental animals and histological structure of visceral organs and skin; evaluation of chronic toxicity showed that the preparation induced no changes in blood biochemical parameters compared to the control.
Martynov
A K
AK
Laboratory of Experimental Hemosorption and Oxidative Methods of Detoxication, Institute of Physicochemical Medicine, Federal Agency on Health Care and Social Development, Moscow.
Artemkina
I V
IV
Laptanovich
A A
AA
Egorov
D Y
DY
Tsesarskii
A A
AA
Belova
O V
OV
Arion
V Y
VY
D028341:Activins; D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D003879:Dermatologic Agents / Q000494:pharmacology / Q000633:toxicity*; D006168:Guinea Pigs; D006801:Humans; D051379:Mice; D009824:Ointments / Q000494:pharmacology / Q000633:toxicity; D051381:Rats; D012867:Skin / Q000737:chemistry / Q000187:drug effects / Q000276:immunology; D013552:Swine
D000276:Adjuvants, Immunologic; D003879:Dermatologic Agents; D009824:Ointments; D028341:Activins