title: A rare case of arterial thrombosis in a 37-year-old male with Factor V Leiden mutation.
abstract: BACKGROUND
  The classic triad of symptoms seen in chronic mesenteric ischaemia is post-prandial pain, sitophobia (fear of food) and progressive weight loss. Patients with mesenteric ischaemia secondary to a prothrombotic state such as that rendered by the Factor V Leiden mutation, are substantially younger than the typical elderly patient in whom embolic disease triggered by atrial fibrillation is the main underlying cause.
  
  
  METHODS
  This is one such case report documenting arterial thrombosis in a 37-year-old male with a subsequently identified heterozygous Factor V Leiden mutation.
  
  
  CONCLUSIONS
  Factor V Leiden mutation is a contributing risk factor in cases of small bowel infarction.
authors.affiliation: Department of Surgery, University College Hospital, Galway, Ireland. susanogorman@eircom.net
authors.forename: S
authors.initials: S
authors.lastname: O'Gorman
authors.forename: R
authors.initials: R
authors.lastname: Osman
authors.forename: M
authors.initials: M
authors.lastname: Smith
authors.forename: G
authors.initials: G
authors.lastname: Callagy
authors.forename: M
authors.initials: M
authors.lastname: Regan
authors.forename: M
authors.initials: M
authors.lastname: Kerin
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D005165:Factor V / Q000235:genetics*; D006801:Humans; D007421:Intestine, Small / Q000098:blood supply*; D007511:Ischemia / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D008297:Male; D008638:Mesenteric Arteries / Q000473:pathology*; D012307:Risk Factors; D013927:Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*
chemical_list: C095381:factor V Leiden; D005165:Factor V