title: Essential fatty acid-deprived tube-fed adults synthesize arachidonic and docosahexaenoic acids: a pilot analysis of the fatty acid status of people with profound developmental disabilities.
abstract: OBJECTIVE
  Determine whether there are essential fatty acid abnormalities in arachidonic (AA) and docosahexaenoic acid (DHA)-deprived tube-fed individuals.
  
  
  METHODS
  Plasma fatty acid concentrations were measured in eight tube-fed adults with profound developmental disabilities.
  
  
  RESULTS
  Mean plasma AA, DPAn-6, stearic, oleic, Mead, palmitoleic, and vaccenic acid concentrations were elevated but DHA was normal. Numerous fatty acid ratios were also elevated.
  
  
  CONCLUSIONS
  In this context, significant synthesis of both AA and DHA was apparent. However, abnormal fatty acid profiles were common.
authors.affiliation: Central Wisconsin Center, 317 Knutson Drive, Madison, WI 53704, USA. glicknr@dhfs.state.wi.us
authors.forename: Norris R
authors.initials: NR
authors.lastname: Glick
authors.forename: Milton H
authors.initials: MH
authors.lastname: Fischer
mesh_terms: D000328:Adult; D001095:Arachidonic Acids / Q000096:biosynthesis / Q000097:blood*; D002648:Child; D002658:Developmental Disabilities / Q000097:blood*; D004281:Docosahexaenoic Acids / Q000097:blood* / Q000378:metabolism; D004750:Enteral Nutrition; D005228:Fatty Acids, Essential / Q000172:deficiency*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D001095:Arachidonic Acids; D005228:Fatty Acids, Essential; D004281:Docosahexaenoic Acids