Cervical cancer screening: from molecular basis to diagnostic practice, going through new technologies.
In the era of Human Papillomavirus (HPV) vaccination, a lot of misunderstanding still exists among healthcare professionals and patients regarding HPV infection. The purpose of this review is to synthesize the clinical molecular mechanisms that contribute to HPV-mediated cervical carcinogenesis, as well as to appraise the current status of new biomarkers and technologies in terms of available data on clinical applications and future promises.
Zappacosta
Roberta
R
Cytopathology Unit, Department of Oncology and Neuroscience. G d'Annunzio University, Chieti-Pescara, Italy.
Rosini
Sandra
S
D005260:Female; D006801:Humans; D008403:Mass Screening; D027383:Papillomaviridae / Q000276:immunology; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000453:epidemiology; D053918:Papillomavirus Vaccines / Q000627:therapeutic use; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000821:virology
D053918:Papillomavirus Vaccines