Dammarane- and taraxastane-type triterpenoids from Saussurea oligantha Franch.
A new dammarane triterpenoid oliganthas A (1) and a new taraxastane triterpenoid oliganthas B (2), as well as five known taraxastane triterpenoids, ptiloepoxide (3), taraxast-20(30)ene-3beta,21alpha-diol (4), 22-oxo-20-taraxasten-3beta-ol (5), taraxast-20-ene-3beta,30-diol (6), and taraxastane-3beta,20alpha-diol (7), were isolated from the whole plant of Saussurea oligantha Franch. Their structures were elucidated by a series of spectroscopic methods. These compounds, especially taraxastanes 2, 5, and 6, exhibited significant antibacterial activity against Actinomyces viscosus ATCC27044.
Li
Xue-Hu
XH
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China.
Qi
Huan-Yang
HY
Shi
Yan-Ping
YP
D016924:Actinomyces viscosus / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure; D030441:Saussurea / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004365:Drugs, Chinese Herbal; D014315:Triterpenes