title: Non-hyaluronic acid fillers.
abstract: Fillers are numerous, and the products currently available have effects that may last from a few months to many years. These are used to treat facial wrinkles, and some of the new fillers exert a stimulatory effect, restoring volume in focal areas of the face by inducing collagen fibers. The dermasurgeon should thoroughly understand the indications and uses of these fillers to meet fully a patient's expectations. Some fillers are biodegradable (12-18 months), others slowly biodegradable (2-5 years), whereas others are permanent implants. The disadvantage of the traditional biodegradable fillers is their short duration (6-12 months). Over the past decade, semipermanent fillers (polylactic acid and ceramics) have been used: they do have a longer effect, but they might induce granulomas especially on the lips. Also, permanent fillers are traditionally linked to a higher incidence of granulomas and extrusions, although with the new formulations, the adverse events are decreased.
authors.affiliation: St. Louis University, Paris, France. drdaphnetb@free.fr
authors.forename: Daphne
authors.initials: D
authors.lastname: Thioly-Bensoussan
mesh_terms: D020341:Absorbable Implants / Q000009:adverse effects / Q000145:classification*; D001672:Biocompatible Materials / Q000009:adverse effects / Q000145:classification* / Q000627:therapeutic use; D003094:Collagen / Q000009:adverse effects / Q000145:classification* / Q000627:therapeutic use; D003357:Cosmetic Techniques; D005145:Face; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D007271:Injections, Intradermal; D012060:Rejuvenation; D015595:Skin Aging
chemical_list: D001672:Biocompatible Materials; D003094:Collagen