title: Two cases of vaginitis caused by itraconazole-resistant Saccharomyces cerevisiae and a review of recently published studies.
abstract: Genitourinary infections caused by non-Candida yeasts are uncommon, and especially due to Saccharomyces cerevisiae. We describe the cases of two adult females with vulvovaginal infections caused by itraconazole-resistant S. cerevisiae who made a full recovery after oral fluconazole therapy. We also provide a concise review of recently published studies on this topic.
authors.affiliation: Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, "Spirito Santo" Hospital, v. Fonte Romana 8, 65100 Pescara, Italy. vincsavi@yahoo.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Savini
authors.forename: Chiara
authors.initials: C
authors.lastname: Catavitello
authors.forename: Assunta
authors.initials: A
authors.lastname: Manna
authors.forename: Marzia
authors.initials: M
authors.lastname: Talia
authors.forename: Fabio
authors.initials: F
authors.lastname: Febbo
authors.forename: Andrea
authors.initials: A
authors.lastname: Balbinot
authors.forename: Francesco
authors.initials: F
authors.lastname: D'Antonio
authors.forename: Giovanni
authors.initials: G
authors.lastname: Di Bonaventura
authors.forename: Claudio
authors.initials: C
authors.lastname: Celentano
authors.forename: Marco
authors.initials: M
authors.lastname: Liberati
authors.forename: Raffaele
authors.initials: R
authors.lastname: Piccolomini
authors.forename: Domenico
authors.initials: D
authors.lastname: D'Antonio
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis; D003937:Diagnosis, Differential; D025141:Drug Resistance, Fungal; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*; D014627:Vaginitis / Q000188:drug therapy / Q000382:microbiology*; D014848:Vulvovaginitis / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole