Primary biliary cirrhosis: the future.
Primary biliary cirrhosis is a progressive cholestatic liver disease of presumed autoimmune etiology. Patterns of disease are changing with earlier recognition and better access to investigation and treatment. With the convergence of animal, genetic, and clinical studies over the coming years, it is hoped that a greater understanding in the pathophysiology of the disease will translate into improved clinical endpoints for patients.
Hirschfield
Gideon M
GM
Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street, 6B Fell, Room 154, Toronto, Ontario, M5T 2S8, Canada.
Heathcote
E J
EJ
D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011379:Prognosis