title: Accumulation of Ade(+) reversions in isoauxotrophic strains ofSaccharomyces cerevisioe allelic inRAD6 during adenine starvation.
abstract: A comparative method based on an analysis of accumulation of starvation-induced Ade(+) reversions and cell death during adenine starvation was developed and exploited for estimating the role ofRAD6 in the starvation-induced reversions. It was shown that inactivation ofRAD6 function inSaccharomyces cerevisioe markedly enhances the accumulation of Ade(+) reversions, and therefore it is likely that this gene is taking part in maintaining the low level of starvation-induced mutations in yeast cells.
authors.affiliation: Department of Genetics and Microbiology, Faculty of Science, Charles University, 128 44, Prague, Czech Republic.
authors.forename: Z
authors.initials: Z
authors.lastname: Storchová
authors.forename: A P
authors.initials: AP
authors.lastname: Rojas Gil
authors.forename: B
authors.initials: B
authors.lastname: Janderová
authors.forename: J
authors.initials: J
authors.lastname: Vlasák
authors.forename: V
authors.initials: V
authors.lastname: Vondrejs