title: Caecal metastasis from breast cancer presenting as intestinal obstruction.
abstract: BACKGROUND
  Gastrointestinal metastsasis from the breast cancer are rare. We report a patient who presented with intestinal obstruction due to solitary caecal metastasis from infiltrating ductal carcinoma of breast. We also review the available literature briefly.
  
  
  METHODS
  A 72 year old lady with past history of breast cancer presented with intestinal obstruction due to a caecal mass. She underwent an emergency right hemicolectomy. The histological examination of the right hemicolectomy specimen revealed an adenocarcinoma in caecum staining positive for Cytokeratin 7 and Carcinoembryonic antigen and negative for Cytokeratin 20, CDX2 and Estrogen receptor. Eight out of 11 mesenteric nodes showed tumour deposits. A histological diagnosis of metastatic breast carcinoma was given.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first case report of solitary metastasis to caecum from infiltrating ductal carcinoma of breast. Awareness of this possibility will aid in appropriate management of such patients.
authors.affiliation: Department of General Surgery, University Hospital of Hartlepool, Hartlepool, TS24 9AH, UK. rpbirla@gmail.com
authors.forename: Rashmi
authors.initials: R
authors.lastname: Birla
authors.forename: Kamal Kumar
authors.initials: KK
authors.lastname: Mahawar
authors.forename: Mavis
authors.initials: M
authors.lastname: Orizu
authors.forename: Muhammad S
authors.initials: MS
authors.lastname: Siddiqui
authors.forename: Arun
authors.initials: A
authors.lastname: Batra
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001943:Breast Neoplasms / Q000473:pathology*; D000071616:CDX2 Transcription Factor; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002430:Cecal Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*; D005260:Female; D018398:Homeodomain Proteins / Q000032:analysis; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D053552:Keratin-7 / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D000071616:CDX2 Transcription Factor; C491270:CDX2 protein, human; D002272:Carcinoembryonic Antigen; D018398:Homeodomain Proteins; D053552:Keratin-7