Energetics of protein translocation into mitochondria.
Biogenesis of mitochondria depends on the coordinated action of at least six protein translocases present in both mitochondrial membranes. They use different energy sources to drive unidirectional transport of proteins across and into mitochondrial membranes. Here we present an overview on the energetic requirements of different mitochondrial import pathways.
Mokranjac
Dejana
D
Institute for Physiological Chemistry and Munich Center for Integrated Protein Science CIPS(M), Ludwig-Maximilians University, Butenandtstr. 5, 81377 Munich, Germany.
Neupert
Walter
W
D002352:Carrier Proteins / Q000378:metabolism; D003545:Cysteine / Q000378:metabolism; D004734:Energy Metabolism; D008928:Mitochondria / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism*; D008954:Models, Biological; D021381:Protein Transport; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*
D002352:Carrier Proteins; D011506:Proteins; D003545:Cysteine