title: Selective detrending method for reducing task-correlated motion artifact during speech in event-related FMRI.
abstract: Task-correlated motion artifacts that occur during functional magnetic resonance imaging can be mistaken for brain activity. In this work, a new selective detrending method for reduction of artifacts associated with task-correlated motion (TCM) during speech in event-related functional magnetic resonance imaging is introduced and demonstrated in an overt word generation paradigm. The performance of this new method is compared with that of three existing methods for reducing artifacts because of TCM: (1) motion parameter regression, (2) ignoring images during speech, and (3) detrending time course datasets of signal components related to TCM (deduced from artifact corrupted voxels). The selective detrending method outperforms the other three methods in reducing TCM artifacts and in retaining blood oxygenation level dependent signal.
authors.affiliation: Department of Radiology, UT Southwestern Medical Center, Dallas, Texas 753908896, USA. kaundinya.gopinath@utsouthwestern.edu
authors.forename: Kaundinya
authors.initials: K
authors.lastname: Gopinath
authors.forename: Bruce
authors.initials: B
authors.lastname: Crosson
authors.forename: Keith
authors.initials: K
authors.lastname: McGregor
authors.forename: Kyung
authors.initials: K
authors.lastname: Peck
authors.forename: Yu-Ling
authors.initials: YL
authors.lastname: Chang
authors.forename: Anna
authors.initials: A
authors.lastname: Moore
authors.forename: Megan
authors.initials: M
authors.lastname: Sherod
authors.forename: Christy
authors.initials: C
authors.lastname: Cavanagh
authors.forename: Ashley
authors.initials: A
authors.lastname: Wabnitz
authors.forename: Christina
authors.initials: C
authors.lastname: Wierenga
authors.forename: Keith
authors.initials: K
authors.lastname: White
authors.forename: Sergey
authors.initials: S
authors.lastname: Cheshkov
authors.forename: Venkatagiri
authors.initials: V
authors.lastname: Krishnamurthy
authors.forename: Richard W
authors.initials: RW
authors.lastname: Briggs
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000098:blood supply*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009038:Motion; D010100:Oxygen / Q000097:blood; D012044:Regression Analysis; D012815:Signal Processing, Computer-Assisted; D013060:Speech / Q000502:physiology*
chemical_list: D010100:Oxygen