title: Papulonecrotic tuberculids associated with uveitis.
abstract: Papulonecrotic tuberculids represent an immunological expression of an internal focus of tuberculosis in an individual with a moderate or high degree of immunity. It responds to anti-tuberculosis treatment and is characterized by an eruption of necrotizing papules occurring in symmetrical crops, particularly affecting the elbows, knees, buttocks and face. A case of papulonecrotic tuberculids associated with immune mediated unilateral uveitis is reported in which all investigations were negative for tuberculosis except a strongly positive tuberculin test. There was an excellent response to anti-tuberculosis treatment. The association of immune mediated uveitis with papulonecrotic tuberculids has not been described before.
authors.affiliation: Department of Dermatology, Combined Military Hospital, Lahore.
authors.forename: Nasser Rashid
authors.initials: NR
authors.lastname: Dar
authors.forename: Naeem
authors.initials: N
authors.lastname: Raza
authors.forename: Omar
authors.initials: O
authors.lastname: Zafar
authors.forename: Salahuddin
authors.initials: S
authors.lastname: Awan
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D014374:Tuberculin Test; D014382:Tuberculosis, Cutaneous / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014392:Tuberculosis, Ocular / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin