Antibiotic resistance of Gardnerella vaginalis in recurrent bacterial vaginosis.
Fifty strains of Gardnerella vaginalis isolated from 321 high vaginal swabs over a period of five months were tested for their antibiotic sensitivity. Sixty eight per cent of all isolates were resistant to metronidazole while 76% were sensitive to clindamycin. All the strains isolated from cases with recurrence of infection were resistant to metronidazole. Clindamycin therapy has a better clinical efficacy than metronidazole in cases of recurrent bacterial vaginosis.
Nagaraja
P
P
Department of Microbiology, Farwaniya Hospital, Post Box 18373, Kuwait 81004, State of Kuwait. dr.prem@indiatimes.com
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005260:Female; D006194:Gardnerella vaginalis / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D014621:Vagina / Q000382:microbiology; D016585:Vaginosis, Bacterial / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D008795:Metronidazole; D002981:Clindamycin