title: Evaluation of the effectiveness of peracetic acid in the sterilization of dental equipment.
abstract: OBJECTIVE
  To evaluate the effectiveness of peracetic acid in the microbiological sterilisation of dental materials.
  
  
  METHODS
  Peracetic acid solution was evaluated at concentrations of 800, 1500 and 2500 ppm. At these concentrations, it was determined whether peracetic acid caused corrosion to dental instruments and induced cellular mutagenicity and cytotoxicity. In addition, the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC), agar diffusion and diffusion by well method, were also verified.
  
  
  RESULTS
  The corrosion rate, calculated from potentiodynamic assays was 10(-6) cm/year, indicating that the product does not damage equipment. The sterilisation capacity of peracetic acid at 2500 ppm was the best. The comet assay indicated genotoxic activity at 2500 ppm.
  
  
  CONCLUSIONS
  This study demonstrated the effectiveness of peracetic acid for sterilizing dental equipment, providing another alternative for the prevention of infections in clinics.
authors.affiliation: UNESC-Programa de Pós-Graduação em Ciências da Saúde Av. Universitária, 1105 ZIP 88806-000 SC, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Ceretta
authors.forename: M M S
authors.initials: MM
authors.lastname: Paula
authors.forename: Ev
authors.initials: E
authors.lastname: Angioletto
authors.forename: M M
authors.initials: MM
authors.lastname: Méier
authors.forename: F G
authors.initials: FG
authors.lastname: Mitellstädt
authors.forename: C T
authors.initials: CT
authors.lastname: Pich
authors.forename: S A
authors.initials: SA
authors.lastname: Junior
authors.forename: E
authors.initials: E
authors.lastname: Angioletto
mesh_terms: D001419:Bacteria / Q000187:drug effects; D001773:Blood Cells / Q000187:drug effects; D002470:Cell Survival; D020552:Comet Assay; D004247:DNA / Q000187:drug effects; D003748:Dental Equipment / Q000382:microbiology*; D004202:Disinfectants / Q000494:pharmacology* / Q000633:toxicity; D004203:Disinfection / Q000379:methods*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010463:Peracetic Acid / Q000494:pharmacology* / Q000633:toxicity; D010586:Phagocytes / Q000187:drug effects; D013778:Tetrazolium Salts / Q000378:metabolism; D013844:Thiazoles / Q000378:metabolism
chemical_list: D004202:Disinfectants; D013778:Tetrazolium Salts; D013844:Thiazoles; D004247:DNA; C022616:thiazolyl blue; D010463:Peracetic Acid