title: [Dual-thermotherapy for parenchymal hepatic cells carcinoma].
abstract: OBJECTIVE
  To study the efficacy and safety of transhepatic arterial "dual-thermotherapy" (DT) for parenchymal hepatic cells carcinoma.
  
  
  METHODS
  Fifty patients (mean age 55.5 years, DT group) with parenchymal hepatic cells carcinoma were treated with transhepatic arterial thermochemotherapy with warmed lipiodol (80 degrees C) and warmed chemotherapeutic agents (50 degrees C). Another 50 patients (mean age 54 years) were treated with ordinary transhepatic arterial chemomembolization (TACE) with the same chemotherapeutic drugs but without warming (TACE group).
  
  
  RESULTS
  The 1-, 2-, and 3-year survival rates were 77.6%, 53.1% and 46.1%, respectively, in TD group; and 54.4%, 24.2% and 16.1%, resectively, in TACE group; the difference was statistically significant(P<0.05). The sidejeffect of the feeling of cauterization (cases/persistence time) in DT group was statistically significant compared with TACE group (P<0.05), and the difference was not statistically significant about other side-effects.
  
  
  CONCLUSIONS
  Transhepatic arterial perfusion of warmed lipiodol (80 degrees C) and chemotherapeutic agents (50 degrees C), namely, "dual-thermotherapy" is a simple, safe and effective method for treating hepatic carcinoma with less complications than ordinary TACE.
authors.affiliation: Department of Interventional Medical, the First Hospital of Lanzhou University, Lanzhou 730000, China. wangwenhui1968@126.com
authors.forename: Wen hui
authors.initials: Wh
authors.lastname: Wang
authors.forename: Fen qiang
authors.initials: Fq
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Guo
authors.forename: Dong jun
authors.initials: Dj
authors.lastname: Su
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Lai chang
authors.initials: Lc
authors.lastname: Song
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007269:Injections, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015996:Survival Rate
chemical_list: D007459:Iodized Oil