title: Evaluation of injectable CaHA for the treatment of mid-face volume loss.
abstract: BACKGROUND
  Calcium hydroxylapatite (CaHA) is presently approved for the correction of moderate to severe facial wrinkles and folds and signs of HIV-associated facial lipoatrophy.
  
  
  OBJECTIVE
  This 6-month pilot study was designed to evaluate clinical efficacy and patient satisfaction of CaHA to treat mid-face volume loss.
  
  
  METHODS
  Nineteen patients received initial malar injections of CaHA. At 1, 3, and 6 months, patients were evaluated for mid-face volume loss, satisfaction, and adverse events. Touch ups were administered at 3 months, with enhancement injections permitted at 6 months.
  
  
  RESULTS
  Average treatment volumes were 1.3 mL CaHA gel per side. At 1, 3, and 6 months, 88%, 74%, and 75% of patients rated themselves "very satisfied/satisfied" and physicians rated 82%, 100%, and 94% of patients as "im proved" or greater, respectively. Global Aesthetic Improvement Scale (GAIS) scores were similar. At 6 months, 88% of patients were pleased with the outcome and 81% would recommend CaHA cheek augmentation.
  
  
  CONCLUSIONS
  Malar augmentation with CaHA gel appears to be a viable nonsurgical alternative for patients with mid-face volume loss, with good patient satisfaction and excellent tolerability.
authors.affiliation: Palm Beach Esthetic Center, West Palm Beach, FL 33401, USA. kenbeer@aol.com
authors.forename: Kenneth
authors.initials: K
authors.lastname: Beer
authors.forename: Monica
authors.initials: M
authors.lastname: Yohn
authors.forename: Joel L
authors.initials: JL
authors.lastname: Cohen
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002610:Cheek; D003357:Cosmetic Techniques; D017886:Durapatite / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005782:Gels; D039682:HIV-Associated Lipodystrophy Syndrome / Q000628:therapy*; D006801:Humans; D007271:Injections, Intradermal; D008875:Middle Aged; D017060:Patient Satisfaction; D010865:Pilot Projects; D012060:Rejuvenation
chemical_list: D005782:Gels; D017886:Durapatite