title: Reversible posterior encephalopathy syndrome in systemic lupus erythematosus and lupus nephritis.
abstract: Reversible posterior encephalopathy syndrome (RPES) is a clinical entity characterized with headache, nausea, vomiting, seizures, consciousness disturbance, and frequently visual disorders associated with neuroradiological findings, predominantly white matter abnormalities of the parieto-occipital lobes. The central nervous system manifestations of systemic lupus erythematosus (SLE) are highly diverse. However, SLE-associated RPES has been seldom reported. Here, we report a case with RPES in SLE and lupus nephritis with exclusive involvement of parietal and occipital cortices. A systematic review of the literature on the pathogenesis and treatment of SLE-associated RPES is included.
authors.affiliation: Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China.
authors.forename: Yan-Xing
authors.initials: YX
authors.lastname: Zhang
authors.forename: Jian-Ren
authors.initials: JR
authors.lastname: Liu
authors.forename: Mei-Ping
authors.initials: MP
authors.lastname: Ding
authors.forename: Jian
authors.initials: J
authors.lastname: Huang
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Olav
authors.initials: O
authors.lastname: Jansen
authors.forename: Günther
authors.initials: G
authors.lastname: Deuschl
authors.forename: Christoph Cyrill
authors.initials: CC
authors.lastname: Eschenfelder
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D017315:Cilazapril / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008181:Lupus Nephritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D054038:Posterior Leukoencephalopathy Syndrome / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology
chemical_list: D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D017315:Cilazapril