title: Bilateral femur metastasis in endometrial adenocarcinoma.
abstract: Bone metastasis of endometrial carcinoma is uncommon, and bilateral femur metastasis is extremely rare. A 48-year-old woman with Federation International of Gynecology and Obstetrics stage IIB grade 2-3 endometrial adenocarcinoma underwent curative radical hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymphadenectomy followed by radiotherapy and chemotherapy. Twenty-two months after surgery, she suffered from progressive pain and then presented bilateral femur metastasis. She was administered the surgical excision of bony metastasis and adjuvant therapies including chemotherapy, palliative radiation, and hormone therapy. Three and a half years after treatment of bony metastasis, she remains clinically well. Bone metastasis of endometrial carcinoma may occur at some unusual sites, and bilateral femur metastasis should be considered in patients. Multimodal therapies are usually advocated for bone metastasis of endometrial carcinoma.
authors.affiliation: Division of Gynecologic Oncology, Department of Ob/Gyn, West China Second University Hospital, Sichuan University, Chengdu, Peoples Republic of China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Qin
authors.forename: Zhilan
authors.initials: Z
authors.lastname: Peng
authors.forename: Yan
authors.initials: Y
authors.lastname: Gao
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed