title: Primary osseous melanoma in the tibia of a dog.
abstract: An 18-month-old, female Cane Corso dog was presented with a suspected primary tumor of the tibia. Plain radiographs and computed tomography (CT) of the tibia were highly suggestive of a primary bone neoplasm. A diagnosis of malignant melanoma was made by cytology. Total body survey radiographs, CT scan of the thorax, and abdominal ultrasound excluded the presence of neoplastic lesions other than in the tibia. Limb amputation was performed. Histology and immunohistochemical analysis of the tibial neoplasm confirmed the diagnosis of a melanoma with secondary metastasis to the popliteal lymph node. The dog was alive and in good physical condition 43 months after surgery.
authors.affiliation: Department of Veterinary Clinical Sciences, School of Veterinary Medicine, University of Milan, Via Celoria 10, Milan, 20133, Italy.
authors.forename: Damiano
authors.initials: D
authors.lastname: Stefanello
authors.forename: Stefano
authors.initials: S
authors.lastname: Romussi
authors.forename: Paola
authors.initials: P
authors.lastname: Signorelli
authors.forename: Mario
authors.initials: M
authors.lastname: Caniatti
authors.forename: Mauro
authors.initials: M
authors.lastname: DiGiancamillo
authors.forename: Paola
authors.initials: P
authors.lastname: Roccabianca
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Avallone
mesh_terms: D000671:Amputation, Surgical; D000818:Animals; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005260:Female; D006614:Hindlimb; D007794:Lameness, Animal / Q000150:complications; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000662:veterinary; D016896:Treatment Outcome