Isolation of urease-positive Ochrobactrum intermedium in the stomach of a non-ulcer dyspeptic patient from north India.
Ochrobactrum intermedium is an opportunistic human pathogen found in immunocompromised individuals. We report the case of a north Indian patient with non-ulcer dyspepsia whose gastric biopsy revealed the presence of O. intermedium, along with Helicobacter pylori. Further description of O. intermedium was performed with 16S rRNA (1500 nucleotides) and RecA (1065 nucleotides) gene sequencing, and the identity and phylogenetic affiliation of the isolate was confirmed by 100% nucleotide similarity with O. intermedium LMG3301. Further investigation is required in order to evaluate the link between H. pylori and O. intermedium in the gastric niche.
Dharne
Mahesh S
MS
Molecular Biology Unit, National Centre for Cell Science, Ganeshkhind Road, Pune University Campus, Pune, Maharashtra, India.
Misra
Sri Prakash
SP
Misra
Vatsala
V
Dwivedi
Manisha
M
Patole
Milind S
MS
Shouche
Yogesh S
YS
D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D004415:Dyspepsia / Q000382:microbiology* / Q000473:pathology; D016946:Gram-Negative Aerobic Rods and Cocci / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007194:India; D008297:Male; D008969:Molecular Sequence Data; D042041:Ochrobactrum / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D013270:Stomach / Q000382:microbiology* / Q000473:pathology; D014510:Urease / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D014510:Urease