Familial poikylodermic cutaneous amyloidosis.
Among the less common variants of primary cutaneous amyloidosis are both the poikylodermic and the familial types. The case of two sisters of thirteen and seventeen years old with extensive asymptomatic lesions with a poikylodermic aspect is reported. The girls' father was also affected and a paternal aunt had consulted at our department some years previously for similar lesions. Thus a new case of familial cutaneous amyloidosis with an autosomal dominant hereditary pattern is described. The possible relationship between multiple endocrine neoplasia type 2A (MEN-2A) and familial cutaneous amyloidosis is discussed.
Pardo Arranz
Lourdes
L
Hospital Universitario de Salamanca, Servicio de Dermatología, Paseo de San Vicente 58-132, 37007 Salamanca, Spain. pardolourdes@yahoo.es
Escalonilla García-Patos
Pilar
P
Román Curto
Concepción
C
Blanco Barrios
Susana
S
Fernández López
Emilia
E
de Unamuno Pérez
Pablo
P
D000293:Adolescent; D000682:Amyloid / Q000032:analysis*; D028226:Amyloidosis, Familial / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D018813:Multiple Endocrine Neoplasia Type 2a / Q000150:complications; D010375:Pedigree; D010859:Pigmentation Disorders / Q000209:etiology* / Q000235:genetics; D012867:Skin / Q000378:metabolism / Q000473:pathology*
D000682:Amyloid