title: Central coherence in eating disorders: a systematic review.
abstract: BACKGROUND
  This review systematically appraised the research evidence for local versus global information processing to test the hypothesis that people with eating disorders (ED) had weak central coherence.
  
  
  METHODS
  Searches on Medline, EMBASE, PsycINFO and ISI Web of Science databases were conducted in November 2006 and subsequently updated in September 2007. Each search was conducted in two steps: (1) neuropsychological tasks measuring central coherence and (2) words related to cognitive functioning in eating disorders. Data were summarized in a meta-analysis if the number of studies for a given test was >5.
  
  
  RESULTS
  Data were extracted from 16 studies. Meta-analyses were conducted for four tasks obtaining moderate effect sizes. The majority of studies found global processing difficulties across the ED spectrum. The results are less clear regarding local processing.
  
  
  CONCLUSIONS
  People with ED have difficulties in global processing. It is less certain as to whether they have superior local processing. Currently, there is insufficient evidence to refute the weak central coherence hypothesis.
authors.affiliation: Division of Psychological Medicine, Eating Disorders Research Unit, Institute of Psychiatry, King's College London, London, UK. carolina.lopez@iop.kcl.ac.uk
authors.forename: C
authors.initials: C
authors.lastname: Lopez
authors.forename: K
authors.initials: K
authors.lastname: Tchanturia
authors.forename: D
authors.initials: D
authors.lastname: Stahl
authors.forename: J
authors.initials: J
authors.lastname: Treasure
mesh_terms: D003072:Cognition Disorders / Q000453:epidemiology*; D003865:Major Depressive Disorder / Q000453:epidemiology / Q000523:psychology; D001068:Feeding and Eating Disorders / Q000453:epidemiology*; D006801:Humans; D010641:Phenotype