title: Light irradiation is a factor in the bactericidal activity of silver-loaded zeolite.
abstract: Silver loaded zeolite (Ag-Z) was previously found to have effective bactericidal activity against Escherichia coli. To understand the mechanisms of bactericidal activity of Ag-Z, role of light irradiation was focused and investigated in this study. In this study, we focused on light irradiation. Antibacterial assay and spectroscopic study revealed that light irradiation enabled Ag-Z to reduce dioxygen to form a reactive oxygen species, which led to bactericidal activity. These results indicate that the onset of bactericidal activity can be controlled by light irradiation.
authors.affiliation: Department of Microbiology, Showa Pharmaceutical University, Machida, Tokyo, Japan. inoue@ac.shoyaku.ac.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Inoue
authors.forename: Makoto
authors.initials: M
authors.lastname: Kogure
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Hajime
authors.initials: H
authors.lastname: Hamashima
authors.forename: Masamichi
authors.initials: M
authors.lastname: Tsukada
authors.forename: Kazutoyo
authors.initials: K
authors.lastname: Endo
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Tanaka
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects*; D001419:Bacteria / Q000187:drug effects* / Q000201:enzymology / Q000528:radiation effects*; D015169:Colony Count, Microbial; D045304:Cytochromes c / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D004926:Escherichia coli / Q000187:drug effects / Q000528:radiation effects; D008027:Light; D010100:Oxygen / Q000737:chemistry / Q000528:radiation effects; D017382:Reactive Oxygen Species / Q000378:metabolism; D012834:Silver / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects*; D013056:Spectrophotometry, Ultraviolet; D017641:Zeolites / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects*
chemical_list: D000900:Anti-Bacterial Agents; D017382:Reactive Oxygen Species; D017641:Zeolites; D012834:Silver; D045304:Cytochromes c; D010100:Oxygen