A new entry to cascade organocatalysis: reactions of stable sulfur ylides and nitroolefins sequentially catalyzed by thiourea and DMAP.
A novel cascade organocatalysis that allows efficient and rapid access to diverse and structurally complex oxazolidin-2-ones from simple starting materials and catalysts has been developed. A possible mechanism of this reaction has been proposed based on D- and 13C-labeling experiments.
Lu
Liang-Qiu
LQ
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
Cao
Yi-Ju
YJ
Liu
Xiao-Peng
XP
An
Jing
J
Yao
Chang-Jiang
CJ
Ming
Zhi-Hui
ZH
Xiao
Wen-Jing
WJ
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D009574:Nitro Compounds / Q000737:chemistry; D023303:Oxazolidinones / Q000138:chemical synthesis*; D011725:Pyridines / Q000737:chemistry*; D013457:Sulfur Compounds / Q000737:chemistry*; D013890:Thiourea / Q000737:chemistry*
C417980:4-(dimethylamine)pyridine; D000475:Alkenes; D009574:Nitro Compounds; D023303:Oxazolidinones; D011725:Pyridines; D013457:Sulfur Compounds; D013890:Thiourea