title: [Previous screening for cervical cancer among women with cytological and histological abnormalities].
abstract: OBJECTIVE
  To examine previous Pap smear history in women screened for cervical cancer with cytological or histological abnormalities.
  
  
  METHODS
  Cross-sectional study in a sample of 5,485 women (15-65 years old) who self-referred to cervical cancer screening in Sao Paulo and Campinas, Southeastern Brazil, between February 2002 and March 2003. A behavioral questionnaire was applied and cervical specimens were obtained for testing by Pap smears or liquid-based cytology. Women who had abnormal cytology were referred for colposcopic examination and, if abnormal, for cervical punch biopsy. To explore factors associated to cervical abnormalities Pearson's chi-square test was conducted at a 5% significance level.
  
  
  RESULTS
  Cytological abnormalities were found in 354 women (6.4%) and included 41 high-grade squamous intra-epithelial lesions and 3 carcinomas; 92.7% were normal results. Colposcopy was performed in 289 women, and 145 (50.2%) showed abnormal results. Punch biopsies showed 14 cervical intraepithelial neoplasias grade 3 and 4 carcinomas. Previous Pap smears were reported in all women who had cytology suspected of carcinoma, 97.6% of those with high-grade squamous intra-epithelial lesions, all women with histological diagnosis of carcinoma and 92.9% of those who had cervical intraepithelial neoplasias grade 3 histologically. Previous Pap smear in the last tree years was reported by 86.5% and 92.8% of women with abnormal cytology and biopsy, respectively.
  
  
  CONCLUSIONS
  There was no statistically significant difference regarding the number of Pap tests and time since their last test between women with histologically diagnosed carcinoma and cervical intraepithelial neoplasia grade 3 compared with those with normal cytology.
authors.affiliation: Hospital Leonor Mendes de Barros, Avenida Celso Garcia 2477, São Paulo, SP, Brazil. crisrama@usp.br
authors.forename: C
authors.initials: C
authors.lastname: Rama
authors.forename: C
authors.initials: C
authors.lastname: Roteli-Martins
authors.forename: S
authors.initials: S
authors.lastname: Derchain
authors.forename: A
authors.initials: A
authors.lastname: Longatto-Filho
authors.forename: R
authors.initials: R
authors.lastname: Gontijo
authors.forename: L
authors.initials: L
authors.lastname: Sarian
authors.forename: K
authors.initials: K
authors.lastname: Syrjanen
authors.forename: T
authors.initials: T
authors.lastname: Ching
authors.forename: J
authors.initials: J
authors.lastname: Aldrighi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D065006:Papanicolaou Test; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears / Q000706:statistics & numerical data*; D002578:Uterine Cervical Dysplasia / Q000473:pathology*