title: Synthesis, Structure and Antitumour Properties of a New 1,2-Propylenediaminetetraacetate-Ruthenium(III) Compound.
abstract: A novel complex formed by ruthenium (III) and the sequestering ligand 1,2-propylenediaminetetraacetic acid (PDTA) has been synthetized and characterized. The structure of the monomeric compound, studied by X-ray diffraction , shows an almost symmetric octahedral geometry around the metal ion, with two chlorine atoms in a cis conformation. The antitumour activity against a variety of murine and human cancers is reported.
authors.affiliation: Dpto. de Quífmica Inorgánica F. de Química Universidad de Sevilla Sevilla 41071 Spain.
authors.forename: R
authors.initials: R
authors.lastname: Vilaplana
authors.forename: M A
authors.initials: MA
authors.lastname: Romero
authors.forename: M
authors.initials: M
authors.lastname: Quirós
authors.forename: J M
authors.initials: JM
authors.lastname: Salas
authors.forename: F
authors.initials: F
authors.lastname: González-Vílchez