Ossifying fibromyxoid tumor of oral cavity.
Ossifying fibromyxoid tumor is a rare tumor of mesenchymal origin with varied presentation at different sites including head and neck. Clinically these are slow growing lesions and patients have a variable age at presentation. A 14 years old girl presented with a slowly enlarging gingival swelling, which on radiological examination showed increased rarefaction in the mandible with a provisional diagnosis of an inflammatory lesion. Microscopically, the tumor had spindle to oval shaped cells in a fibromyxoid background with a peripheral shell of lamellar bone. Histological diagnosis of ossifying fibromyxoid tumor was made after immunohistochemical stains for vimentin and S-100 protein. Recurrence, metastasis and histologically increased mitotic count are indicative of atypical or malignant ossifying fibromyxoid tumors.
Sharif
Muhammad Ashraf
MA
Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi. ashrafof@gmail.com
Mushtaq
Sajid
S
Mamoon
Nadira
N
Khadim
Muhammad Tahir
MT
D000293:Adolescent; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D018214:Fibroma, Ossifying / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D014408:Biomarkers, Tumor; D009418:S100 Proteins; D014746:Vimentin