title: Impact of hysterectomy on stress urinary incontinence: an identical twin study.
abstract: OBJECTIVE
  This study uses the unique properties of twin research design to evaluate whether hysterectomy impacts stress urinary incontinence (SUI).
  
  
  METHODS
  As part of the Evanston Twins Sister Study, we performed bivariate and multivariate analyses on 83 identical twin pairs discordant for hysterectomy.
  
  
  RESULTS
  In bivariate analysis, SUI was less common in women who had prior hysterectomy (P =0.028). Multivariate analysis suggested that SUI was significantly less common after hysterectomy (odds ratio [OR], 0.55, confidence interval [CI], 0.30 to 1.00). Exclusion of twin pairs with a history of pelvic floor defect surgery eliminated the statistical relationship between hysterectomy and SUI (OR, 0.79, CI, 0.4 to 1.40).
  
  
  CONCLUSIONS
  Hysterectomy, when analyzed with all cases, was associated with reduced SUI. When concurrent pelvic floor defect surgeries were excluded from the analysis, we found no relationship between hysterectomy and the risk of SUI afterward.
authors.affiliation: Miller Urogynecology, Bloomington, IL, USA. jmiller@millergyn.com
authors.forename: Jay-James R
authors.initials: JJ
authors.lastname: Miller
authors.forename: Sylvia M
authors.initials: SM
authors.lastname: Botros
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Beaumont
authors.forename: Sarit O
authors.initials: SO
authors.lastname: Aschkenazi
authors.forename: Tondalaya
authors.initials: T
authors.lastname: Gamble
authors.forename: Peter K
authors.initials: PK
authors.lastname: Sand
authors.forename: Roger P
authors.initials: RP
authors.lastname: Goldberg
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D004200:Diseases in Twins / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D015999:Multivariate Analysis; D010298:Parity; D011247:Pregnancy; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014430:Twins, Monozygotic; D014550:Urinary Incontinence, Stress / Q000453:epidemiology*; D014596:Uterine Prolapse / Q000453:epidemiology* / Q000601:surgery*