Growth and the modeling/remodeling of the alveolar bone of the rat incisor.
The modeling and remodeling of the rat incisor alveolar bone was followed as the animals grew. The weight of the hemimandible, the length of the socket, and the width of the lower incisor were measured. Osteoclasts and resorption areas were identified by tartrate-resistant acid phosphatase staining. Fluorochrome markers were used to detect and measure osteogenic activities. In the socket related to the periodontal ligament, osteoclasts appeared in scattered sites as well as isolated sites of osteogenic activity, apparently without any variation related to the age of the animals. At the socket facing the dental follicle of young rats, the inner surface was lined with osteoclasts. The number of osteoclasts decreased steadily as the rats grew. In 1-year-old rats, in addition to a few scattered osteoclasts, the internal aspect of the labial wall showed some sites lined with osteoblasts and cement lines indicative of prior bone formation. In young rats, there was a continuous osteogenic activity at the external surface of this wall. The thickness of the labial wall of the socket remained apparently constant; therefore, bone resorption must have occurred at the internal side of the wall. Such osteogenic activity was not observed in old rats. The main forces acting on rat incisors, biting and eruption, are continuous through the life of the animals. Thus, these results indicate that the modeling of the alveolar bone related to the dental follicle, in young rats, can only be associated with another force, specifically, the growth of the incisor.
Merzel
José
J
Department of Morphology, Faculdade de Odontologia de Piracicaba, State University of Campinas -UNICAMP, SP, Brazil. jmerzel@fop.unicamp.br
Salmon
Cristiane R
CR
D000539:Alveolar Process / Q000033:anatomy & histology / Q000254:growth & development*; D000818:Animals; D016723:Bone Remodeling; D005260:Female; D007180:Incisor / Q000033:anatomy & histology / Q000254:growth & development*; D008297:Male; D008334:Mandible / Q000254:growth & development; D009805:Odontogenesis; D010010:Osteoclasts / Q000166:cytology; D010012:Osteogenesis; D051381:Rats; D017208:Rats, Wistar; D013194:Staining and Labeling; D020390:Tooth Socket / Q000033:anatomy & histology / Q000254:growth & development