title: Quality of life after infection in total joint replacement.
abstract: OBJECTIVE
  To compare the health-related quality of life and functional outcomes of patients with and without periprosthetic infection after total joint replacement (TJR).
  
  
  METHODS
  62 uncomplicated TJRs and 34 TJRs complicated with deep infection were compared using a visual analogue scale for satisfaction, the Western Ontario and McMaster Universities Osteoarthritis Index, Assessment of Quality of Life, and Short Form-36.
  
  
  RESULTS
  Patients with complicated TJR had significantly poorer satisfaction in outcome (p<0.0001) and disease-specific functional outcomes (p<0.0001). Six of the 8 health-related quality-of-life scores were also significantly poorer (p<0.05). These results persisted after controlling for age, sex, and follow-up period in a multiple regression analysis.
  
  
  CONCLUSIONS
  Infection following TJR reduces patient satisfaction and seriously impairs functional health status and health-related quality of life. When hospitals are balancing the costs of preventative measures with the costs of treating infection in TJR, the effect on patients' quality of life must be considered. Our findings argue strongly for allocation of health care resources to minimise the occurrence of infection after TJR.
authors.affiliation: Trauma and Orthopaedic Research Unit, The Canberra Hospital, Canberra, Australia. jenny.cahill@act.gov.au
authors.forename: J L
authors.initials: JL
authors.lastname: Cahill
authors.forename: B
authors.initials: B
authors.lastname: Shadbolt
authors.forename: J M
authors.initials: JM
authors.lastname: Scarvell
authors.forename: P N
authors.initials: PN
authors.lastname: Smith
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D005260:Female; D006304:Health Status; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D016459:Prosthesis-Related Infections; D011788:Quality of Life