[A case of hematomyelia caused by coagulation--fibrinolysis abnormality accompanied with colon cancer and its metastasis].
A 76-year-old woman developed weakness and sensory loss in the lower limbs and urinary disturbance in four days. She had a history of operation for the ascending colon cancer and lung metastasis one year ago. Neurological examination revealed flaccid paraplegia, absent Achilles tendon reflex, severe disturbance of superficial and deep sensation below the L3 level, and vesicorectal abnormality. Magnetic resonance imaging (MRI) studies showed an intramedullary T1-iso, T2-low lesion with Gd-DTPA contrast enhancement in conus medullaris at LI level. The laboratory examination revealed the elevated level of serum FDP. D-dimer and TAT. She was diagnosed as hematomyelia, which may be caused by the activation of coagulation and fibrinolysis system. We suggested that the ascending colon cancer and lung metastasis may contribute to the coagulation-fibrinolysis abnormality.
Abe
Yoshitake
Y
Department of Neurology and Neuromuscular Disorders, Oita University Faculty of Medicine.
Hazama
Yusuke
Y
Hanaoka
Takuya
T
Kimura
Noriyuki
N
Arakawa
Ryuki
R
Kumamoto
Toshihide
T
D000368:Aged; D001778:Blood Coagulation Disorders / Q000150:complications*; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000556:secondary; D020758:Spinal Cord Vascular Diseases / Q000209:etiology*