[Interaction of influenza A and B viruses with a carbon-containing sorbent].
The investigation demonstrated that influenza A and B viruses actively interacted with a sorbent obtained from modified oxygen-containing graphite via hydrothermal treatment irrespective of the antigenic structure of surface proteins. Virionic sorption occurred in a wide range of temperatures from 8 to 34 degrees C for 15 min or more. After interaction with the sorbent, the titer of a virus decreased 4- to 256-fold. The immobilized viruses were able to interact with homologous antibodies and immune sera. Desorption of viruses with the sorbent was extremely slight. In addition to viruses, the proteins of nonviral nature--those of allantoic hen embryo liquid, immune serum, and 1% bovine serum albumin--could be immobilized to the sorbent.
Ivanova
V T
VT
Kurochkina
Ia E
IaE
Buravtsev
V N
VN
Nikolaev
A V
AV
Timofeeva
A V
AV
Baratova
L A
LA
D000042:Absorption; D000914:Antibodies, Viral / Q000276:immunology; D000918:Antibody Specificity; D006108:Graphite / Q000737:chemistry / Q000378:metabolism*; D007106:Immune Sera / Q000276:immunology; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology / Q000378:metabolism*; D053122:Influenza A Virus, H3N2 Subtype / Q000378:metabolism*; D009981:Influenza B virus / Q000276:immunology / Q000378:metabolism*; D010100:Oxygen; D013696:Temperature; D013997:Time Factors
D000914:Antibodies, Viral; D007106:Immune Sera; D006108:Graphite; D010100:Oxygen