title: [Exposure to multiresisant tuberculosis: study and follow-up of nine children].
abstract: A world increase in multidrug-resistant tuberculosis (MDR-TB) has been reported over the last few years. A larger number of diagnoses are being seen in Spain, due to the increase of immigration from high endemic TB countries. Articles published on this are anecdotal in children, and there is no clear directives for treatment of MDR-TB, or latent tuberculosis infection (ITBL) or on prophylaxis after exposure to active pulmonary MDR-TB. We present the initial management and progression of nine children after close contact exposure to an Ecuadorian woman diagnosed with active pulmonary TB, resistant to Isoniazid, Rifampicin and Pyrazinamide.
authors.affiliation: Servicio de Pediatría, Hospital Carlos III, Madrid, España. roipineiroperez@telefonica.net
authors.forename: R
authors.initials: R
authors.lastname: Piñeiro Pérez
authors.forename: M J
authors.initials: MJ
authors.lastname: Mellado Peña
authors.forename: A
authors.initials: A
authors.lastname: Méndez Echevarría
authors.forename: M J
authors.initials: MJ
authors.lastname: Cilleruelo Ortega
authors.forename: M
authors.initials: M
authors.lastname: García Hortelano
authors.forename: J
authors.initials: J
authors.lastname: Villota Arrieta
authors.forename: P
authors.initials: P
authors.lastname: Martín Fontelos
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007538:Isoniazid; D008297:Male; D011718:Pyrazinamide; D012293:Rifampin; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin