[Development and assessment of a new test for verification of tests for HIV-infection markers].
The OOO "Research-and-Production Association "Diagnostic Systems" has developed a "DC-EIA-HIV-AT/AG-SPECTRUM" screening enzyme immunoassay system designed to detect separately antibodies to certain HIV-1 and HIV-2 proteins, as well as antigen p24. The determination of antibodies of all classes and the marker of early-stage infection antigen p24 with a high (5 pg/ml) sensitivity substantially reduces the number of void results obtained in the use of immunoblots. The developed "DC-EIA-HIV-AT/AG-SPECTRUM" plate system is an effective tool to support positive screening results and may be used at the final stage of laboratory diagnosis of HIV infection.
Baranova
E N
EN
Sharipova
I N
IN
Kudriavtseva
E N
EN
Lobanova
O A
OA
Puzyrev
V F
VF
Riabinina
S A
SA
Burkov
A N
AN
Obriadina
A P
AP
Ulanova
T I
TI
D000956:Antigens, Viral / Q000737:chemistry / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D000939:Epitopes / Q000737:chemistry / Q000276:immunology; D015483:HIV Antibodies / Q000097:blood* / Q000276:immunology; D015658:HIV Infections / Q000097:blood* / Q000276:immunology; D015497:HIV-1 / Q000737:chemistry / Q000276:immunology; D015498:HIV-2 / Q000737:chemistry / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods / Q000592:standards; D011994:Recombinant Proteins / Q000737:chemistry / Q000276:immunology; D012680:Sensitivity and Specificity
D000956:Antigens, Viral; D015415:Biomarkers; D000939:Epitopes; D015483:HIV Antibodies; D011994:Recombinant Proteins