Preparation of genipin cross-linked chitosan-gelatin microcapsules for encapsulation of Zanthoxylum limonella oil (ZLO) using salting-out method.
Zanthoxylum limonella oil (ZLO) containing chitosan-gelatin complex microcapsules cross-linked with genipin, a cross-linker of natural origin, have been prepared by a complex coacervation process using the salting-out method. The effects of various parameters such as oil loading, degree of cross-linking, ratio of chitosan to gelatin, etc. on oil content, encapsulation efficiency and the release rate of ZLO have been studied. FT-IR spectroscopy has been used to understand the interaction between the polymers and oil. Scanning electron microscopy (SEM) has been employed to study the morphology of the prepared microcapsules.
Hussain
M R
MR
Department of Chemical Sciences, Tezpur University, Assam, India.
Maji
T K
TK
D002214:Capsules; D048271:Chitosan / Q000737:chemistry*; D002756:Cholagogues and Choleretics / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry*; D004339:Drug Compounding; D005780:Gelatin / Q000737:chemistry*; D057889:Iridoid Glycosides; D039823:Iridoids / Q000008:administration & dosage*; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D009821:Oils / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D012492:Salts / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D032106:Zanthoxylum
D002214:Capsules; D002756:Cholagogues and Choleretics; D003432:Cross-Linking Reagents; D057889:Iridoid Glycosides; D039823:Iridoids; D009821:Oils; D010936:Plant Extracts; D012492:Salts; D005780:Gelatin; D048271:Chitosan; C007834:genipin