Cryptogenic stroke in a boy with atrial septal defect and hyperhomocysteinemia.
In children, clinical recognition of stroke and determination of its exact etiology are extremely difficult. The authors described a case of cryptogenic stroke in a 14-year-old-boy with asymptomatic atrial septal defect and hypercoagulable state. Paradoxical embolism was hypothesized as the responsible etiopathological mechanism. It is crucial to increase clinician awareness of stroke in children.
Indolfi
Giuseppe
G
Department of Pediatrics, University of Florence, Anna Meyer Children's Hospital, Florence, Italy. g.indolfi@meyer.it
Bartolini
Elisa
E
Trapani
Sandra
S
Azzari
Chiara
C
Resti
Massimo
M
D000293:Adolescent; D017668:Age of Onset; D000925:Anticoagulants / Q000627:therapeutic use; D025861:Blood Coagulation Disorders, Inherited / Q000150:complications* / Q000235:genetics; D002536:Cerebral Arteries / Q000473:pathology / Q000503:physiopathology; D038524:Diffusion Magnetic Resonance Imaging; D005492:Folic Acid / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006344:Heart Septal Defects, Atrial / Q000150:complications* / Q000235:genetics; D006423:Hemianopsia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications* / Q000235:genetics; D020762:Infarction, Posterior Cerebral Artery / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D020766:Intracranial Embolism / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009778:Occipital Lobe / Q000098:blood supply / Q000473:pathology; D020521:Stroke / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D014805:Vitamin B 12 / Q000627:therapeutic use
D000925:Anticoagulants; D005492:Folic Acid; D014805:Vitamin B 12