title: [Stroke due to spontaneous calcified cerebral embolus as presenting feature of calcified aortic stenosis].
abstract: We report a case of calcified aortic stenosis revealed by an ischemic stroke. An 81-year-old man with hyperlipidemia, hypertension and renal function impairment presented with acute onset of right-sided hemiparesis and aphasia. Head CT scan revealed a rounded calcified high-density mass within the distal segment of the left anterior cerebral artery, consistent with a calcified cerebral embolus, and an infarct in the left paracentral lobule. Transesophageal echocardiography demonstrated a sclerotic aortic valve. The patient was discharged from hospital on aspirin and atorvastatin, and the outcome was favorable. Calcified embolus remains a rare event and it has been not yet reported in the territory of anterior cerebral artery. It may be observed in aortic and mitral valve diseases, calcified plaques of the internal carotid artery and aortic arch. Renal failure promotes their development and is the cause of cardiovascular diseases. To date, aortic valve calcification is not considered as a marker of stroke risk, except when associated with severe stenosis or left ventricular hypertrophy.
authors.affiliation: Service de neurologie, CHU d'Amiens, 80054 Amiens cedex 1, France. bugnicourt.jean-marc@chu-amiens.fr
authors.forename: J-M
authors.initials: JM
authors.lastname: Bugnicourt
authors.forename: B
authors.initials: B
authors.lastname: Bonnaire
authors.forename: L
authors.initials: L
authors.lastname: Lepage
authors.forename: P-Y
authors.initials: PY
authors.lastname: Garcia
authors.forename: M
authors.initials: M
authors.lastname: Lefranc
authors.forename: O
authors.initials: O
authors.lastname: Godefroy
mesh_terms: D000369:Aged, 80 and over; D020771:Anterior Cerebral Artery; D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001241:Aspirin / Q000627:therapeutic use; D000069059:Atorvastatin; D002114:Calcinosis / Q000150:complications / Q000175:diagnosis*; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D020766:Intracranial Embolism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011758:Pyrroles / Q000627:therapeutic use; D020521:Stroke / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D006538:Heptanoic Acids; D011758:Pyrroles; D000069059:Atorvastatin; D001241:Aspirin