IgA nephropathy and small cell lung carcinoma.
The occurrence of glomerular disease as a paraneoplastic manifestation of malignancy is well documented in the medical literature. The strongest association is between membranous glomerulonephritis and solid tumors. We report a patient with IgA nephropathy associated with small cell lung cancer. To our knowledge, this is the second documented occurrence of an IgA nephropathy with a casual association with small cell bronchogenic cancer. This observation leads to the hypothesis that IgA nephropathy might be a paraneoplastic manifestation of this histiologic type of lung cancer.
Yacoub
George
G
Veterans Affairs Medical Center, Mountain Home, TN, USA.
Kosseifi
Semaan G
SG
Shah
Lata S
LS
Byrd
Ryland P
RP
Roy
Thomas M
TM
D018288:Carcinoma, Small Cell / Q000150:complications*; D005922:Glomerulonephritis, IGA / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes