title: Extending the boundaries of no-touch aorta technique usage for coronary artery bypass grafting in patients with diseased ascending aorta.
abstract: OBJECTIVE
  Atherosclerosis of the ascending aorta is a leading cause of cerebrovascular accidents (CVA) in patients who undergo coronary artery bypass grafting (CABG). However, the ascending aorta is considered untouchable only in cases of severe calcification. The aim of this study is to evaluate the effect of the no-touch aorta technique (NAT) on morbidity and mortality with an extension of indication to any degree of atherosclerotic disease is detected on the ascending aorta.
  
  
  METHODS
  From March 2001 to March 2006, data were prospectively collected from 101 patients with ascending aorta atherosclerosis who underwent either on- or off-pump CABG with NAT. Demographic data from these 101 patients were compared with those of 1 473 patients who underwent conventional CABG with aortic cross-clamping during the same time period. All preoperative variables were assessed with stepwise logistic regression to determine predictors of ascending aortic disease.
  
  
  RESULTS
  Age, hypertension, hyperlipidemia, peripheral vascular disease, EuroSCORE and unstable and redo rates were significantly higher in the NAT group than in the control group (P<0.05). Logistic regression analysis of preoperative variables for all 1 574 cases identified age, peripheral vascular disease, history of smoking, EuroSCORE, and reoperation as independent predictors of atherosclerotic disease of the ascending aorta. No operative or hospital CVA occurred in the study group. Hospital mortality was observed in 2 (1.9%) patients. During the follow-up period of 27.9 +/- 13 months, no patient was re-admitted with angina recurrence or CVA.
  
  
  CONCLUSIONS
  Any degree of atherosclerotic disease on the ascending aorta can potentially cause CVA upon manipulation during CABG. Use of CABG with NAT to eliminate the risk of CVA is associated with low rates of morbidity, stroke and mortality during hospital stay and at mid-term follow-up.
authors.affiliation: Department of Cardiovascular Surgery, Adana Teaching and Medical Research Center, Baskent University, Adana, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Gülcan
authors.forename: R
authors.initials: R
authors.lastname: Türköz
authors.forename: O S
authors.initials: OS
authors.lastname: Demirturk
authors.forename: L
authors.initials: L
authors.lastname: Oguzkurt
authors.forename: A
authors.initials: A
authors.lastname: Türköz
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic; D001018:Aortic Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000601:surgery*; D016022:Case-Control Studies; D003287:Contrast Media; D001026:Coronary Artery Bypass / Q000379:methods*; D005260:Female; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide