The anticonvulsant activity of acetone does not depend upon its metabolites.
Gasior
Maciej
M
Hartman
Adam L
AL
Rogawski
Michael A
MA
D000096:Acetone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D001812:Blood-Brain Barrier / Q000187:drug effects / Q000378:metabolism; D004195:Disease Models, Animal; D006801:Humans; D007274:Injections, Intraperitoneal; D007662:Ketosis / Q000139:chemically induced / Q000378:metabolism; D051379:Mice; D011765:Pyruvaldehyde / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012377:Rodentia; D012640:Seizures / Q000178:diet therapy / Q000188:drug therapy* / Q000517:prevention & control; D016896:Treatment Outcome
D000927:Anticonvulsants; D000096:Acetone; D011765:Pyruvaldehyde; C004433:acetol