Cognition and brain imaging in type 1 diabetes.
Type 1 diabetes has mild effects on cognition that are influenced by age of onset, hyperglycemia, and hypoglycemic episodes. Some of these changes occur quite early in the disease course. Studies using relatively new brain imaging techniques have also shown brain changes in adults and children that appear to be influenced by metabolic abnormalities present in diabetes. Early detections of brain changes may be early indicators of subsequent cognitive abnormalities.
Musen
Gail
G
Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USA. gail.musen@joslin.harvard.edu
D000208:Acute Disease; D001921:Brain / Q000378:metabolism / Q000473:pathology*; D003071:Cognition; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism / Q000473:pathology / Q000523:psychology*; D016883:Diabetic Ketoacidosis / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000523:psychology; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy