title: Cardiovascular adaptive responses in rats submitted to moderate resistance training.
abstract: The present study investigated the effects of 8 week of resistance training (RT) on hemodynamic and ventricular function on cardiac myosin ATPase activity, and on contractility of papillary muscles of rats. Groups: control (CO), electrically stimulated (ES), trained at 60% (TR 60%) and 75% of one repetition maximum (1RM) (TR 75%). Exercise protocol: 5 sets of 12 repetitions at 60 and 75% of 1RM, 5 times per week. The CO and ES groups had similar values for parameters analyzed (P > 0.05). Blood pressure (BP), heart rate (13%), left ventricle systolic pressure (LVSP 13%) decreased and cardiac myosin ATPase activity increased in the TR 75% group (90%, P < 0.05). The contractile performance of papillary muscles increased in trained rats (P < 0.05). Eight weeks of RT was associated with lowering of resting BP, heart rate and LVSP, improvements in contractility of the papillary muscle and an increase of cardiac myosin ATPase activity in rats.
authors.affiliation: Department of Physiological Sciences, Federal University of Espírito Santo, Ave. Marechal Campos, Vitoria, Espirito Santo, Brazil.
authors.forename: Rita
authors.initials: R
authors.lastname: de Cássia Cypriano Ervati Pinter
authors.forename: Alessandra Simão
authors.initials: AS
authors.lastname: Padilha
authors.forename: Edilamar Menezes
authors.initials: EM
authors.lastname: de Oliveira
authors.forename: Dalton Valentim
authors.initials: DV
authors.lastname: Vassallo
authors.forename: Juliana Hott
authors.initials: JH
authors.lastname: de Fúcio Lizardo
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D004558:Electric Stimulation; D004594:Electrophysiology; D006339:Heart Rate / Q000502:physiology; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D009200:Myocardial Contraction / Q000502:physiology; D009206:Myocardium / Q000201:enzymology; D009218:Myosins / Q000378:metabolism; D010210:Papillary Muscles / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D009218:Myosins