title: Idiopathic choroidal neovascularization as an early manifestation of inflammatory chorioretinal diseases.
abstract: OBJECTIVE
  We describe four patients with idiopathic choroidal neovascularization (ICNV) who developed inflammatory chorioretinal diseases in the ipsilateral or contralateral eye.
  
  
  METHODS
  The medical records of 58 eyes of 58 patients with an initial diagnosis of ICNV (age range, 19-49 years; mean, 34.9 years) were reviewed.
  
  
  RESULTS
  Of the 58 patients, 4 women (7.0%) with moderate to high myopia (age range, 17-39 years) developed inflammatory chorioretinal diseases. In Cases 1 and 2, white dots were transiently seen in the deep retina of the contralateral eye, consistent with the clinical features of multiple evanescent white dot syndrome (MEWDS). In Case 3, vitritis and multifocal white spots emerged in the ipsilateral eye. These white spots spread throughout the ocular fundus and progressed to punched-out chorioretinal scars, which led to a diagnosis of multifocal choroiditis (MFC). In Case 4, an enlarged blind spot and a few chorioretinal scars around the optic nerve head developed without vitritis in the ipsilateral eye, suggesting a diagnosis of punctate inner choroidopathy (PIC).
  
  
  CONCLUSIONS
  These findings suggest that ICNV can be an early manifestation of inflammatory chorioretinal diseases, including MEWDS, MFC, and PIC.
authors.affiliation: Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan. smachida@iwate-med.ac.jp
authors.forename: Shigeki
authors.initials: S
authors.lastname: Machida
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Murai
authors.forename: Masabumi
authors.initials: M
authors.lastname: Kubo
authors.forename: Daijiro
authors.initials: D
authors.lastname: Kurosaka
mesh_terms: D000328:Adult; D002825:Chorioretinitis / Q000175:diagnosis / Q000209:etiology*; D020256:Choroidal Neovascularization / Q000150:complications* / Q000175:diagnosis; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008875:Middle Aged; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green