Structure, formation and catalytic studies of a meso-palladioporphyrin intermediate in a Heck reaction.
A meso-palladioporphyrin intermediate was isolated from a Heck reaction between an iodoporphyrin and a non-activated olefin using a Pd(PPh3)2Cl2/Et3N system; its structure was characterized by NMR, MS and X-ray crystallography. Studies on its formation indicate that the Pd(II) catalyst was reduced in situ by Et3N with the assistance of water. The catalytic activity of the intermediate was confirmed by stoichiometric and catalytic reactions using a more reactive olefin, ethyl acrylate.
Jiang
Michael Y
MY
Department of Chemistry, University of British Columbia, Rm W300-6174 University Blvd., Vancouver, BC V6T 1Z3, Canada.
Shin
Ji-Young
JY
Patrick
Brian O
BO
Dolphin
David
D