Three cases of cutaneous phaeohyphomycosis by Exophiala jeanselmei.
Cutaneous phaeohyphomycosis is a rare opportunistic fungal disease, knowledge of which is important because of the increase in organ transplantation, aggressive treatments for malignancies, and chronic use of corticosteroids. We report 3 cases of cutaneous phaeohyphomycosis: two patients treated with oral corticosteroids and one elderly woman with multiple hospitalizations. They showed several different clinical appearances. Histopathologically, the fungal infection affected the dermis and subcutis in all cases and in one of them, also the epidermis. Exophiala jeanselmei was isolated from the purulent exudate in the three cases. Good response was obtained with surgical and antifungal treatment.
Martínez-González
M Covadonga
MC
Dermatology Service, Abente and Lago Hospital, Universitary Hospital Complex Juan Canalejo, C/ Sir John Moore, s/n. 15001- La Coruña. Spain. covadie@yahoo.es
Verea
M Magdalena
MM
Velasco
David
D
Sacristán
Felipe
F
Del Pozo
Jesús
J
García-Silva
Jesús
J
Fonseca
Eduardo
E
D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003881:Dermatomycoses / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D005093:Exophiala / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D012867:Skin / Q000382:microbiology / Q000473:pathology
D000935:Antifungal Agents; D007166:Immunosuppressive Agents