title: A novel steroidal glycoside, ophiofurospiside A from Ophiopogon japonicus (Thunb.) Ker-Gawl.
abstract: A new furospirostanol saponin, ophiofurospiside A (1), was isolated together with the known steroidal glycosides 2, 3, and 4 from the tubers of Ophiopogon japonicus (Thunb.) Ker-Gawl. Using chemical and spectral analyses (IR, MS, 1D NMR, and 2D NMR), the structure of 1 was established as 26-O-beta-d-glucopyranosyl-(22S, 25R)-furospirost-5-ene-3beta, 17alpha, 26-triol-3-O-[alpha-l-rhamnopyranosyl-(1 --> 2)]-[beta-d-xylopyranosyl-(1 --> 4)]-glucopyranoside (1). Three known steroidal saponins 2-4 were identified on the basis of spectroscopic data.
authors.affiliation: Department of Traditional Chinese Medicine Chemistry, Beijing University of Chinese Medicine, Beijing, China.
authors.forename: Tun-Hai
authors.initials: TH
authors.lastname: Xu
authors.forename: Ya-Juan
authors.initials: YJ
authors.lastname: Xu
authors.forename: Sheng-Xu
authors.initials: SX
authors.lastname: Xie
authors.forename: Hong-Feng
authors.initials: HF
authors.lastname: Zhao
authors.forename: Dong
authors.initials: D
authors.lastname: Han
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.forename: Jian-Zhao
authors.initials: JZ
authors.lastname: Niu
authors.forename: Dong-Ming
authors.initials: DM
authors.lastname: Xu
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006027:Glycosides / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D031441:Ophiopogon / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013256:Steroids / Q000302:isolation & purification
chemical_list: C531134:26-O-glucopyranosylfurospirost-5-ene-3,17,26-triol-3-O-(rhamnopyranosyl-1-2)(xylopyranosyl-1-4)glucopyranoside; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D012503:Saponins; D013256:Steroids