Drug-eluting stent implantation for acute myocardial infarction during pregnancy with use of glycoprotein IIb/IIIa inhibitor, aspirin and clopidogrel.
Acute myocardial infarction (AMI) during pregnancy, though rare, is nevertheless associated with a high mortality rate ranging from 37-50%. Percutaneous coronary intervention (PCI) with stenting is considered to be one of the more challenging therapeutic strategies in the management of AMI during pregnancy. We report a case of a 44-year-old pregnant woman who presented with an AMI. She underwent PCI using a drug-eluting stent (DES) with eptifibatide, aspirin and clopidogrel without complications, and later delivered a healthy infant at 36 weeks of gestation. With a tendency towards an increased proportion of births by older women, AMI during pregnancy may become more frequent. The risks and benefits of DES placement and the use of adjuvant antiplatelet therapy for coronary interventions during pregnancy are discussed here.
Al-Aqeedi
Rafid Fayadh
RF
Department of Cardiology and Cardiac Surgery, Hamad Medical corporation, P.O.Box 3050, Doha, Qatar. aalnabti@hmc.org.qa
Al-Nabti
Abdulrahman D
AD
D001241:Aspirin / Q000008:administration & dosage*; D000077144:Clopidogrel; D017023:Coronary Angiography; D054855:Drug-Eluting Stents; D004562:Electrocardiography; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D019919:Prosthesis Implantation; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin