title: Reduction of rib fractures with a bioresorbable plating system: preliminary observations.
abstract: BACKGROUND
  Operative fixation of rib fractures can reduce morbidity and mortality. Currently, resorbable fixation devices are used in a variety of surgical procedures.
  
  
  METHODS
  A standard osteotomy was prepared in 30 New Zealand white rabbits at the 12th rib. Eighteen had surgical repair with bioresorbable plates and 12 underwent nonoperative management. Half the animals in each group were killed at 3-week postfracture and the remaining animals were killed at 6-week postfracture. Ribs were radiographed and processed histologically to assess fracture healing. Rib reduction was defined as the alignment of the rib ends in a structural condition similar to the prefractured state and quantitative radiomorphometry measured the radiopaque callus surrounding the rib injury sites. Statistical analysis was performed using Fisher's exact test and an unpaired Student's t test and significance was established at p < 0.05.
  
  
  RESULTS
  At both the 3- and 6-week intervals, seven of the nine rib fractures remained reduced in the operative group, whereas zero of six and three of six of the rib fractures remained reduced, respectively, in the nonoperative group. A statistically significant increase in radiopaque callus surrounding the rib injury sites was observed at 3 and 6 weeks in the fixed groups.
  
  
  CONCLUSIONS
  Fixation of rib fractures with a bioresorbable miniplate system was superior to nonoperative treatment at the 3-week interval, with a statistically significant increase in radiopaque callus formation at both 3 and 6 weeks. Additional studies will evaluate the biomechanical outcomes and degradation tissue response after extended in vivo intervals.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Oregon Health and Science University, Portland, Oregon, USA.
authors.forename: Kim-Chi
authors.initials: KC
authors.lastname: Vu
authors.forename: Mia E
authors.initials: ME
authors.lastname: Skourtis
authors.forename: Xi
authors.initials: X
authors.lastname: Gong
authors.forename: Minhao
authors.initials: M
authors.lastname: Zhou
authors.forename: Wayne
authors.initials: W
authors.lastname: Ozaki
authors.forename: Shelley R
authors.initials: SR
authors.lastname: Winn
mesh_terms: D000818:Animals; D001860:Bone Plates; D005592:Fracture Fixation / Q000379:methods*; D017102:Fracture Healing; D009104:Multiple Trauma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010027:Osteotomy / Q000379:methods*; D011817:Rabbits; D011859:Radiography; D012253:Rib Fractures / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*