What's the point of the type III secretion system needle?
Recent work by several groups has significantly expanded our knowledge of the structure, regulation of assembly, and function of components of the extracellular portion of the type III secretion system (T3SS) of Gram-negative bacteria. This perspective presents a structure-informed analysis of functional data and discusses three nonmutually exclusive models of how a key aspect of T3SS biology, the sensing of host cells, may be performed.
Blocker
Ariel J
AJ
Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Deane
Janet E
JE
Veenendaal
Andreas K J
AK
Roversi
Pietro
P
Hodgkinson
Julie L
JL
Johnson
Steven
S
Lea
Susan M
SM
D001426:Bacterial Proteins / Q000737:chemistry*; D015374:Biosensing Techniques; D008954:Models, Biological; D008958:Models, Molecular; D020836:Protein Structure, Quaternary; D012760:Shigella / Q000737:chemistry
D001426:Bacterial Proteins