Two cases of vaginitis caused by itraconazole-resistant Saccharomyces cerevisiae and a review of recently published studies.
Genitourinary infections caused by non-Candida yeasts are uncommon, and especially due to Saccharomyces cerevisiae. We describe the cases of two adult females with vulvovaginal infections caused by itraconazole-resistant S. cerevisiae who made a full recovery after oral fluconazole therapy. We also provide a concise review of recently published studies on this topic.
Savini
Vincenzo
V
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, "Spirito Santo" Hospital, v. Fonte Romana 8, 65100 Pescara, Italy. vincsavi@yahoo.it
Catavitello
Chiara
C
Manna
Assunta
A
Talia
Marzia
M
Febbo
Fabio
F
Balbinot
Andrea
A
D'Antonio
Francesco
F
Di Bonaventura
Giovanni
G
Celentano
Claudio
C
Liberati
Marco
M
Piccolomini
Raffaele
R
D'Antonio
Domenico
D
D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis; D003937:Diagnosis, Differential; D025141:Drug Resistance, Fungal; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*; D014627:Vaginitis / Q000188:drug therapy / Q000382:microbiology*; D014848:Vulvovaginitis / Q000188:drug therapy / Q000382:microbiology
D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole