title: Methicillin-resistant Staphylococcus non-aureus infection in an irradiated rhesus macaque (Macaca mulatta).
abstract: We describe a case of methicillin-resistant Staphylococcus non-aureus infection in a rhesus macaque (Macaca mulatta). The nonhuman primate described was part of a research project that involved whole-body gamma irradiation and subsequently developed acute generalized dermatitis with skin dryness, peeling, and erythema around the eyes. After initial evaluation, which included microbiologic culture and 6 d of medical treatment, the animal was euthanized due to concern regarding a possible outbreak of infectious or zoonotic disease. On the basis of skin culture, diagnosis of methicillin-resistant Staphylococcus non-aureus was confirmed. This report underscores the importance of the occupational risk of methicillin-resistant Staphylococcus non-aureus to research and animal care staff in a research animal facility setting.
authors.affiliation: Program of Comparative Medicine, Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Krishnan
authors.initials: K
authors.lastname: Kolappaswamy
authors.forename: Steven T
authors.initials: ST
authors.lastname: Shipley
authors.forename: Ivan I
authors.initials: II
authors.lastname: Tatarov
authors.forename: Louis J
authors.initials: LJ
authors.lastname: DeTolla
mesh_terms: D000818:Animals; D037901:Euthanasia, Animal; D005720:Gamma Rays; D016867:Immunocompromised Host / Q000276:immunology / Q000528:radiation effects; D007165:Immunosuppression Therapy / Q000662:veterinary; D008253:Macaca mulatta; D008297:Male; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D008992:Monkey Diseases / Q000382:microbiology* / Q000473:pathology; D011855:Radiodermatitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D013207:Staphylococcal Skin Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D013210:Staphylococcus / Q000187:drug effects* / Q000302:isolation & purification