Genome-informed contributions to malaria therapies: feeding somewhere down the (pipe)line.
Whole-genome sequences of Plasmodium spp. have helped redefine malaria research, including initiatives that seek to develop drugs, vaccines, and other antimalarial therapies. The problems caused by malaria were brought to the public's attention once more on World Malaria Day (April 25). Unfortunately, the current impact of genome-informed research is not as great as might have been hoped, and the reasons for this and continuing challenges are discussed.
Waters
Andrew P
AP
Division of Infection and Immunity, Institute of Biomedical Life Sciences, University of Glasgow, 120 University Place, Glasgow G12 8TA, Scotland, UK. waters@bio.gla.ac.uk
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology; D018503:Genome, Protozoan; D006801:Humans; D008288:Malaria / Q000188:drug therapy* / Q000469:parasitology* / Q000517:prevention & control; D017780:Malaria Vaccines / Q000276:immunology; D010961:Plasmodium / Q000235:genetics*
D000962:Antimalarials; D017780:Malaria Vaccines