title: [Thermal coagulation of human benign prostatic hyperplasia tissues induced changes in the absorption and scattering properties in spectral range from 590 to 1 064 nm in vitro].
abstract: The optical properties and their differences of native and coagulated human benign prostatic hyperplasia (BPH) tissues were studied in the spectral range from 590 to 1 064 nm in vitro. The measurements were performed using a spectrophotometer with an integrating sphere attachment, and the absorption and scattering properties were assessed from these measurements using the inverse adding-doubling method. The results of measurement showed that the thermal coagulation of BPH tissues induced obviously the decrease in the absorption coefficients in the spectral range from 590 to 1 064 nm. The peaks in the absorption coefficients for native and coagulated BPH tissues were respectively 0.438 and 0.416 mm(-1) corresponding to the same wavelength of 990 nm, the maximum difference in the absorption coefficients of native and coagulated BPH tissues is 86.79% at 1 064 nm, and the minimum difference is 4.74% at 920 nm. The thermal coagulation of BPH tissues induced an increase in the reduced scattering coefficients in the spectral range from 600 to 1 064 nm obviously, and induced a decrease in the reduced scattering coefficients at 590 nm obviously. The peaks in the reduced scattering coefficients for native and coagulated BPH tissues were respectively 1.090 and 1. 449 mm(-1) corresponding to the same wavelength of 970 nm, and other peaks in the reduced scattering coefficients for native and coagulated BPH tissues were respectively 1.116 and 1.627 mm(-1) corresponding to the same wavelength of 1 050 nm, the maximum difference in the reduced scattering coefficients of native and coagulated BPH tissues is 47.73% at 1 064 nm, and the minimum difference is 4.86% at 600 nm.
authors.affiliation: MOE Key Laboratory of Laser Life Science and Institute of Laser Life Science, South China Normal University, Guangzhou 510631, China.
authors.forename: Hua-Jiang
authors.initials: HJ
authors.lastname: Wei
authors.forename: Da
authors.initials: D
authors.lastname: Xing
authors.forename: Bo-Hua
authors.initials: BH
authors.lastname: He
authors.forename: Rong-Hai
authors.initials: RH
authors.lastname: Wu
authors.forename: Huai-Min
authors.initials: HM
authors.lastname: Gu
authors.forename: Guo-Yong
authors.initials: GY
authors.lastname: Wu
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Chen
mesh_terms: D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000473:pathology*; D013053:Spectrophotometry / Q000379:methods*; D013696:Temperature