[Stereotactic multi-target operation for patients with affective disorder].
OBJECTIVE
To explore the efficacy and complication of bilateral multi-target radiofrequency lesion operation in patients with affective disorder.


METHODS
One hundred and eighty-two cases with affective disorder were treated with unstaged bilateral multi-target radiofrequency thermocoagulation. The efficacy was evaluated with the method established in 1990 by the National Psychosurgery Cooperative Group.


RESULTS
After 2 weeks of operation, 86 cases with remarkable improvements, 81 cases with improvements, 15 case with no improvements, no case with progression, total efficient ratio was 91.76%. With 6-54 months of follow-up to all of 166 cases, 38 cases with recovery, 59 cases with remarkable improvements, 52 cases with improvements, 17 cases with no improvements, no case with progression, total efficient ratio was 89.76%. Except for early temporal complication of stereotaxic operation, the long-term complication ratio was less than 1%.


CONCLUSIONS
CT-guided bilateral multi-target operation is prominent in treatment of affective disorder with high efficacy and safety.
Wang
Lian-Zhong
LZ
Institute of Psychosurgery of Chinese People's Liberation Army, Department of Neurosurgery, No. 463 Hospital of People's Liberation Army, Shenyang 110042, China. jswk2007@163.com
Yin
Zhong-Min
ZM
Wen
Hua
H
Jiang
Xiao-Lian
XL
Wang
Lei
L
D000293:Adolescent; D000328:Adult; D017115:Catheter Ablation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000601:surgery*; D013238:Stereotaxic Techniques; D036542:Tomography, Spiral Computed; D016896:Treatment Outcome