title: Sympathetic sweat responses and skin vasomotor reflexes in carpal tunnel syndrome.
abstract: OBJECTIVE
  To investigate cutaneous sympathetic functions in carpal tunnel syndrome (CTS) using sympathetic sweat responses (SSwRs) and skin vasomotor reflexes (SVmRs).
  
  
  METHODS
  In 29 hands (20 patients) with idiopathic CTS, SSwRs were recorded with a sudorometer from the thenar eminence, and SVmRs were used to measure cutaneous blood flow using a Doppler flowmeter placed on the index finger tip. Normal data were obtained from 15 volunteers of similar age.
  
  
  RESULTS
  SSwRs or SVmRs were abnormal in 23 (80%) hands; SSwRs were absent in 38%, whereas SVmRs were abnormally decreased in 59%. Autonomic symptoms were present in 18 (62%) hands; finger edema (38%) and dry hand (35%) were frequent symptoms. Autonomic symptoms, and abnormal SSwRs and SVmRs did not correlate with results of nerve conduction studies.
  
  
  CONCLUSIONS
  Skin sudomotor or vasomotor sympathetic function is frequently impaired in CTS. Susceptibility to compression ischemia may be different in sympathetic unmyelinated and large myelinated fibers.
authors.affiliation: Department of Neurology, Chiba University School of Medicine, Chiba, Japan. kuwabara-s@faculty.chiba-u.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kuwabara
authors.forename: Noriko
authors.initials: N
authors.lastname: Tamura
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: Sonoko
authors.initials: S
authors.lastname: Misawa
authors.forename: Sagiri
authors.initials: S
authors.lastname: Isose
authors.forename: Jong Seok
authors.initials: JS
authors.lastname: Bae
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
authors.forename: Masato
authors.initials: M
authors.lastname: Asahina
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002349:Carpal Tunnel Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000294:innervation*; D013546:Sweating / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D014666:Vasomotor System / Q000503:physiopathology*