Hydroindation of allenes and its application to radical cyclization.
Hydroindation of allenes and radical cyclization of 1,2,7-trienes (allenenes) were accomplished by HInCl2 with high regioselectivity to afford a variety of cyclic compounds. The resulting vinylic indiums could be used for successive coupling reactions in a one-pot procedure. The use of HInCl2 generated slowly in situ is extremely effective for the radical cyclization.
Hayashi
Naoki
N
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Hirokawa
Yusuke
Y
Shibata
Ikuya
I
Yasuda
Makoto
M
Baba
Akio
A