title: Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
abstract: This study compares single-dose ibuprofen pretreatment for postoperative endodontic pain. Thirty-nine emergent patients were randomly assigned to 3 groups: placebo, ibuprofen tablets, or ibuprofen liquigels. Patients recorded their pain levels before and at the end of treatment, then every 6 hours for 24 hours after administration of the medications and standard endodontic treatment. Pain evaluations by using 3 pain scales (visual analog scale [VAS], category, and Heft-Parker) were highly correlated, suggesting the rationale for only using one pain scale in pain studies. No significant differences in postoperative pain levels were found between either single-dose ibuprofen formulation or the placebo control group (P = .84). Patients treated with calcium hydroxide versus obturation did not differ in postoperative pain levels (P = .44). This study suggests that single-dose pretreatment analgesia alone in endodontic pain patients will not significantly reduce postoperative pain below the reduction in pain from endodontic treatment.
authors.affiliation: Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA.
authors.forename: Sayeed
authors.initials: S
authors.lastname: Attar
authors.forename: Walter R
authors.initials: WR
authors.lastname: Bowles
authors.forename: Michael K
authors.initials: MK
authors.lastname: Baisden
authors.forename: James S
authors.initials: JS
authors.lastname: Hodges
authors.forename: Scott B
authors.initials: SB
authors.lastname: McClanahan
mesh_terms: D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D000704:Analysis of Variance; D003790:Dental Pulp Necrosis / Q000628:therapy; D004311:Double-Blind Method; D005157:Facial Pain / Q000517:prevention & control; D005260:Female; D005782:Gels; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010485:Periapical Periodontitis / Q000628:therapy; D011300:Preoperative Care; D011671:Pulpitis / Q000628:therapy; D012390:Root Canal Therapy / Q000379:methods; D018709:Statistics, Nonparametric; D013607:Tablets
chemical_list: D018712:Analgesics, Non-Narcotic; D005782:Gels; D013607:Tablets; D007052:Ibuprofen