A possible new inherited myopathy in a young Labrador retriever.
A 5-month-old, male, Labrador retriever was evaluated for progressive weakness and muscle atrophy. Histologic evaluation of fresh frozen muscle revealed distinct cytoarchitectural changes and central mitochondrial accumulations indistinguishable from those found in the inherited myopathy described in Great Danes. Multiple male littermates and half-siblings were similarly affected.
Cosford
Kevin L
KL
Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan. kmaxcosford@yahoo.com
Taylor
Susan M
SM
Thompson
Logan
L
Shelton
G Diane
GD
D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000235:genetics*; D004285:Dogs; D017809:Fatal Outcome; D008297:Male; D018908:Muscle Weakness / Q000209:etiology / Q000662:veterinary; D009133:Muscular Atrophy / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D009135:Muscular Diseases / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*