title: [Quantification of extracranial ICA stenoses with vessel ultrasound by CCDS and B-flow in comparison to 64-slice multidector CTA, contrast-enhanced MRA and DSA].
abstract: OBJECTIVE
  To evaluate the value of vascular ultrasound determining the pre-interventional degree of distal stenosis in the extracranial internal carotid artery (ICA) by means of color-coded duplex sonography (CCDS) and B-flow. Comparison with contrast-enhanced 64-line CT angiography (CTA), contrast-enhanced MRA (ceMRA) and digital subtraction angiography (DSA).
  
  
  METHODS
  Complementary diagnostics and evaluation of the stenosis by means of CCDS, B-flow, CTA, ceMRA and DSA were performed prior to percutaneous stent-assisted PTA in 21 symptomatic ICA stenosis. Ultrasound diagnostics were carried out with high-resolution linear transducers (5-10 MHz and 9-14 MHz). A bolus-triggered contrast-enhanced multislice CTA (collimation 64x0.5 mm) and a ceMRA (1.5 Tesla) as well as selective DSA were performed in every patient. The degree of distal stenosis was established in accordance to NASCET criteria by averaging 5 single measurements per modality and patient. The source images as well as MPR and MIP reconstructions were evaluated in the CTA and ceMRA. Hemodynamic flow parameters were determined with CCDS and B-flow. The images were assessed by two experienced readers in consensus.
  
  
  RESULTS
  The extent of stenosis ranged from 45 to 95%, averaging 73% (+/-13%). There was a high degree of agreement between the B-flow results (r=0.938), the CCDS (r=0.852), the measurements from the source data of the ceMRA (r=0.9117) and reconstructions of the CTA (r=0.8598) compared to quantitative DSA as a reference technique.
  
  
  CONCLUSIONS
  Compared to selective DSA, vascular ultrasound in combination with CTA and ceMRA increase the reliability of the diagnostic quantification of ICA stenosis.
authors.affiliation: Institut für Röntgendiagnostik Universitätsklinikum Regensburg, Regensburg. thomas.finkenzeller@klinik.uni-regensburg.de
authors.forename: T
authors.initials: T
authors.lastname: Finkenzeller
authors.forename: J
authors.initials: J
authors.lastname: Tacke
authors.forename: D-A
authors.initials: DA
authors.lastname: Clevert
authors.forename: W
authors.initials: W
authors.lastname: Jung
authors.forename: R
authors.initials: R
authors.lastname: Kubale
authors.forename: A
authors.initials: A
authors.lastname: Schreyer
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
authors.forename: E M
authors.initials: EM
authors.lastname: Jung
mesh_terms: D015901:Angiography, Digital Subtraction; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D003287:Contrast Media; D006801:Humans; D007091:Image Processing, Computer-Assisted; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media