title: A fulminant case of renal vein thrombosis in a patient with autoimmune disorder and membranous nephropathy.
abstract: A previously healthy middle-aged woman noted a rapid onset of flank pain with gross hematuria. Enhanced CT scan showed thrombosis of the inferior vena cava and right renal vein. Laboratory findings revealed nephrotic proteinuria, Sjogren's syndrome (SjS), and Graves' disease (GD). A right nephrectomy was performed because of progressive and refractory renal necrosis. Renal specimens showed venous infarction with diffuse hemorrhagic and severe congestive renal necrosis, and membranous nephropathy (MN). The present case was diagnosed as acute renal necrosis due to catastrophic thrombosis in a patient with SjS, GD, and MN. It was thought that sudden development of thrombosis may have been caused by the status of the autoimmune disorders, and the associated MN.
authors.affiliation: Department of Nephrology, The Third Department of Internal Medicine, Showa University School of Medicine, Tokyo.
authors.forename: Mutsuki
authors.initials: M
authors.lastname: Makino
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Honda
authors.forename: Fumito
authors.initials: F
authors.lastname: Miyoshi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ban
authors.forename: Takashi
authors.initials: T
authors.lastname: Katagiri
authors.forename: Taka-Aki
authors.initials: TA
authors.lastname: Matsuyama
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Ota
authors.forename: Osamu
authors.initials: O
authors.lastname: Yoshitake
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kusano
authors.forename: Takanori
authors.initials: T
authors.lastname: Shibata
authors.forename: Tadao
authors.initials: T
authors.lastname: Akizawa
mesh_terms: D000328:Adult; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007668:Kidney / Q000473:pathology; D009336:Necrosis / Q000209:etiology; D012082:Renal Veins / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000150:complications* / Q000276:immunology