title: Naturally occurring hydroxy napthoquinones and their iron complexes as modulators of radiation induced lipid peroxidation in synaptosomes.
abstract: The modulation of radiation induced lipid peroxidation in synaptosomes by iron (II) and iron (III) complexes of two naturally occurring and therapeutically relevant naphthoquinones viz. 5,hydroxy-1,4 naphthoquinone; juglone and 2,hydroxy-1,4 naphthoquinone; lawsone, have been studied. At lower concentrations the complexes enhance lipid peroxidation predominantly through redox cycling as observed for Fe(II)- juglonate while at higher concentrations the complexes tend to limit lipid peroxidation through fast recombinations.
authors.affiliation: Department of Chemistry University of Pune Pune 4110 07 India.
authors.forename: A S
authors.initials: AS
authors.lastname: Kumbhar
authors.forename: S B
authors.initials: SB
authors.lastname: Padhye
authors.lastname: Jitender
authors.forename: R K
authors.initials: RK
authors.lastname: Kale