[Effect of 11-deoxymisoprostol ethyl ether sodium salt on thrombocyte aggregation and prothrombin time].
11-Deoxymisoprostol demonstrates antiaggregant properties with respect to the adrenalin-, collagen-, and ADP-induced aggregation of thrombocytes, which is manifested by a decrease in the rate of blood platelet agglutination and their secretion, and by an increase in the time of thrombus formation.
Gabdrakhmanova
S F
SF
Makara
N S
NS
Sapozhnikova
T V
TV
Baschenko
N Zh
NZh
Nazarov
V S
VS
Zarudiĭ
F S
FS
D000244:Adenosine Diphosphate / Q000378:metabolism; D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology; D003094:Collagen / Q000378:metabolism; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D016595:Misoprostol / Q000031:analogs & derivatives* / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D011517:Prothrombin Time
C475855:2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol; D010975:Platelet Aggregation Inhibitors; D016595:Misoprostol; D000244:Adenosine Diphosphate; D003094:Collagen; D004837:Epinephrine