title: [Factors associated with abstinence in a smoking cessation program].
abstract: BACKGROUND
  Smoking cessation programs have an efficacy of approximately 30%. Different factors related to the patients may influence this figure.
  
  
  OBJECTIVE
  To identify determinant factors for smoking cessation after one year of treatment and to determine if bupropion and nicotine substitutes are effective in smoking cessation treatments.
  
  
  METHODS
  Follow up of 68 patients that attended a smokers clinic at a General Hospital. The patients filled up a questionnaire which included demographic, morbid and smoking habits data. They were subjected to a psychiatric interview to determine their treatment. One year later, patients were contacted by telephone and were asked if they remained without smoking.
  
  
  RESULTS
  After one year, 41% of patients responded that they were abstinent. On univariate analysis, male gender appeared as a protective factor associated to abstinence. On multivariate analysis, the use of bupropion appeared as a protective factor. A high score on the automatic item of the smoking motivation questionnaire appeared as a risk factor. The presence of respiratory diseases and the male gender were borderline significant protective factors. Nicotine substitutes were not associated with better abstinence rates.
  
  
  CONCLUSIONS
  In this sample of smokers, the use of bupropion was associated with better abstinence rates and a high motivation to smoke appeared as a risk factor to continue smoking.
authors.affiliation: Servicio de Salud Metropolitano Central, Pontificia Universidad Católica de Chile, Santiago de Chile. natalia.tamblay@redsalud.gov.cl
authors.forename: Natalia
authors.initials: N
authors.lastname: Tamblay
authors.forename: Daniel
authors.initials: D
authors.lastname: Seijas
mesh_terms: D016642:Bupropion / Q000627:therapeutic use*; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000627:therapeutic use*; D018722:Nicotinic Agonists / Q000627:therapeutic use*; D012907:Smoking / Q000188:drug therapy*; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology
chemical_list: D018722:Nicotinic Agonists; D016642:Bupropion; D009538:Nicotine