Isolation and characterization of a novel Francisella sp. from human cerebrospinal fluid and blood.
We describe the isolation of a Francisella sp. from normally sterile sites in acutely ill patients in two different states within 2 years. Microbiologic and molecular analyses indicate that this organism represents a novel Francisella sp. Clinicians and microbiologists should be aware of this new potential pathogen, as infection may be more common than recognized.
Kugeler
Kiersten J
KJ
Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, Colorado 80521, USA.
Mead
Paul S
PS
McGowan
Karin L
KL
Burnham
Jon M
JM
Hogarty
Michael D
MD
Ruchelli
Eduardo
E
Pollard
Kerry
K
Husband
Brigitte
B
Conley
Caryn
C
Rivera
Tanya
T
Kelesidis
Theodoros
T
Lee
Walter M
WM
Mabey
Walburga
W
Winchell
Jonas M
JM
Stang
Heather L
HL
Staples
J Erin
JE
Chalcraft
Linda J
LJ
Petersen
Jeannine M
JM
D000369:Aged, 80 and over; D000372:Agglutination Tests; D016470:Bacteremia / Q000382:microbiology; D015373:Bacterial Typing Techniques; D001769:Blood / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D005603:Francisella / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008590:Meningoencephalitis / Q000382:microbiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S