title: Correlation of intraoperative blood flow measurement with autogenous arteriovenous fistula outcome.
abstract: BACKGROUND
  Autogenous arteriovenous fistula (AVF) has proven to be the optimal vascular access for the majority of hemodialysis patients due to its durability and low complication rates. The purpose of this study is to determine the value of intraoperative blood flow measurement with respect to AVF short-term outcome.
  
  
  METHODS
  A prospective cohort study enrolled patients undergoing first time AVF creation surgery for hemodialysis from November 2001 to April 2007. Intraoperative blood flow measurements were collected using transit time flowmeter, and primary and secondary patency rates of AVF were examined. Other variables including age, sex, the presence of diabetes, hypertension, or cerebrovascular disease, current smoking, systolic and diastolic blood pressure, heart rate, serum calcium-phosphate product, and triglyceride and cholesterol level were analyzed.
  
  
  RESULTS
  Autogenous radiocephalic AVFs (n = 109) in 109 patients were constructed and followed up for an average of 21 months. Among these, 54% of patients were 60 years or older, 51% were male, and 56% were diabetics. One-year primary and secondary patency rates for the high-flow group (> or =200 mL/min) were 69% and 94%, respectively. One-year primary and secondary patency rates for the low-flow group (<200 mL/min) was 52% and 80%, respectively. Using hazard analysis, intraoperative blood flow was the most important determinant of primary and secondary patency, in addition to the presence of diabetes.
  
  
  CONCLUSIONS
  Intraoperative blood flow measurement is a predictor of the primary and secondary patency of autogenous radiocephalic AVFs. Awareness of the significant correlation between intraoperative AVF blood flow and the short-term outcome would enhance the surgical efficiency and maximize the usefulness of autogenous AVF.
authors.affiliation: Division of Cardiovascular Surgery, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, College of Medicine, Fu Jen Catholic University, Taipei, Taiwan. m00678@ms.skh.org.tw
authors.forename: Chia-Hsun
authors.initials: CH
authors.lastname: Lin
authors.forename: Chai-Hock
authors.initials: CH
authors.lastname: Chua
authors.forename: Shou-Shan
authors.initials: SS
authors.lastname: Chiang
authors.forename: Jer-Young
authors.initials: JY
authors.lastname: Liou
authors.forename: Huei-Fong
authors.initials: HF
authors.lastname: Hung
authors.forename: Chung-Hsin
authors.initials: CH
authors.lastname: Chang
mesh_terms: D000368:Aged; D001166:Arteriovenous Shunt, Surgical; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood; D016016:Proportional Hazards Models; D012039:Regional Blood Flow; D006435:Renal Dialysis; D012907:Smoking / Q000453:epidemiology; D014654:Vascular Patency / Q000502:physiology
chemical_list: D010710:Phosphates; D002118:Calcium