Pre-operative DTI and probabilisitic tractography in four patients with deep brain stimulation for chronic pain.
This study aimed to examine, using diffusion tensor imaging (DTI), differences in electrode placement in four patients undergoing deep brain stimulation for chronic neuropathic pain of varying aetiology. A pre-operative DTI was obtained for each patient, who was then implanted with deep brain stimulation electrodes in the periventricular/periaqueductal grey area with good pain relief. Using seeds from the postoperative MRI scan, probabilistic tractography was performed from the pre-operative DTI.
Owen
S L F
SL
Oxford Functional Neurosurgery, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK. sarah.owen@physiology.ox.ac.uk
Heath
J
J
Kringelbach
M
M
Green
A L
AL
Pereira
E A C
EA
Jenkinson
N
N
Jegan
T
T
Stein
J F
JF
Aziz
T Z
TZ
D001931:Brain Mapping / Q000379:methods; D002908:Chronic Disease; D046690:Deep Brain Stimulation / Q000295:instrumentation / Q000379:methods*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004567:Electrodes, Implanted; D006801:Humans; D015233:Models, Statistical; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery; D010148:Intractable Pain / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D010487:Periaqueductal Gray / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care / Q000295:instrumentation / Q000379:methods*; D013238:Stereotaxic Techniques / Q000295:instrumentation*