title: Controlling the clonal spread of Pseudomonas aeruginosa infection.
abstract: To evaluate nosocomial infections due to imipenem-resistant and imipenem-susceptible Pseudomonas aeruginosa, a case-control study that included genotyping was performed. Hospitalization for more than 15 days was independently associated with infection with an imipenem-resistant organism. Sixty-seven percent of the imipenem-resistant isolates analyzed and 23% of the imipenem-susceptible isolates analyzed belonged to a single clone. Intervention led to a decrease in the number of infections due to imipenem-resistant and imipenem-susceptible P. aeruginosa.
authors.affiliation: Institute of Infectious Diseases Emilio Ribas, Faculdade de Medicina, University of São Paulo, Brazil. ghpereira1@terra.com.br
authors.forename: Graziella H
authors.initials: GH
authors.lastname: Pereira
authors.forename: Anna S
authors.initials: AS
authors.lastname: Levin
authors.forename: Helenice Bosco
authors.initials: HB
authors.lastname: Oliveira
authors.forename: Maria Luiza
authors.initials: ML
authors.lastname: Moretti
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016022:Case-Control Studies; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D017053:Infection Control / Q000379:methods; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000187:drug effects* / Q000235:genetics; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem