Kinetic barriers and the role of topology in protein and RNA folding.
This review compares the folding behavior of proteins and RNAs. Topics covered include the role of topology in the determination of folding rates, major folding events including collapse, properties of denatured states, pathway heterogeneity, and the influence of the mode of initiation on the folding pathway.
Sosnick
Tobin R
TR
University of Chicago, 929 East 57th Street, GCIS W107E, Chicago, IL 60637, USA. trsosnic@uchicago.edu
D000818:Animals; D006801:Humans; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D011489:Protein Denaturation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*
D011506:Proteins; D012313:RNA