Anaesthesia for Angelman syndrome.
We describe the administration of anaesthesia to a patient with Angelman syndrome, which is characterised by an abnormality of chromosome 15, where a subunit of the GABA receptor is coded. This has far-reaching anaesthetic implications as many drugs used in anaesthesia are thought to act via GABA receptors. Our patient had an uneventful peri-operative period and was discharged home on the second postoperative day.
Ramanathan
K R
KR
Department of Anaesthetics, Prince Charles Hospital, Merthyr Tydfil, UK. krramanathan@yahoo.com
Muthuswamy
D
D
Jenkins
B J
BJ
D000769:Anesthesia, Inhalation / Q000379:methods*; D017204:Angelman Syndrome / Q000235:genetics / Q000601:surgery*; D002675:Child, Preschool; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics; D006801:Humans; D008297:Male; D018079:Receptors, GABA / Q000235:genetics; D013363:Submandibular Gland / Q000601:surgery
D018079:Receptors, GABA