title: Beta-papillomavirus infection and skin cancer.
abstract: The development of highly sensitive PCR techniques and multiplex bead-based Luminex platforms has accelerated the search for a specific role of human papilloma viruses in the development of squamous cell carcinoma. Human papillomaviruses are most likely indirectly involved in this process by facilitating UV-related carcinogenesis via preventing UV-induced apoptosis or impairing DNA repair, but other mechanisms are also possible.
authors.affiliation: Department of Dermatology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands. j.n.bouwes_bavinck@lumc.nl
authors.forename: Jan Nico
authors.initials: JN
authors.lastname: Bouwes Bavinck
authors.forename: Elsemieke I
authors.initials: EI
authors.lastname: Plasmeijer
authors.forename: Mariet C W
authors.initials: MC
authors.lastname: Feltkamp
mesh_terms: D052686:Betapapillomavirus / Q000378:metabolism*; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D004260:DNA Repair; D015972:Gene Expression Regulation, Neoplastic; D015967:Gene Expression Regulation, Viral; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control / Q000821:virology; D020411:Oligonucleotide Array Sequence Analysis; D030361:Papillomavirus Infections / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology*; D014412:Tumor Virus Infections / Q000150:complications / Q000821:virology; D014466:Ultraviolet Rays