title: Synthesis of poly(sorbitan methacrylate) hydrogel by free-radical polymerization.
abstract: Hydrogels are materials with the ability to swell in water through the retention of significant fractions of water within their structures. Owing to their relatively high degree of biocompatibility, hydrogels have been utilized in a host of biomedical applications. In an attempt to determine the optimum conditions for hydrogel synthesis by the free-radical polymerization of sorbitan methacrylate (SMA), the hydrogel used in this study was well polymerized under the following conditions: 50% (w/v) SMA as monomer, 1% (w/w) alpha, alpha'-azo-bis(isobutyro-nitrile) as thermal initiator, and 1% (w/w) ethylene glycol dimethacrylate as cross-liking agent. Under these conditions, the moisture content of the polymerized SMA hydrogel was higher than in the other conditions. Moreover, the moisture content of the poly(SMA) hydrogel was also found to be higher than that of the poly(methyl methacrylate [MMA]) hydrogel. When the Fourier transform-infrared spectrum of poly(SMA) hydrogel was compared with that of poly(MMA) hydrogel, we noted a band at 1735-1730/cm, which did not appear in the Fourier transform-infrared spectrum of poly(MMA). The surface of the poly(SMA) hydrogel was visualized through scanning electron microscopy, and was uniform and clear in appearance.
authors.affiliation: School of Biological Sciences and Technology, Chonnam National University, 500-757, Gwangju, Korea.
authors.forename: Gwi-Taek
authors.initials: GT
authors.lastname: Jeong
authors.forename: Kyoung-Min
authors.initials: KM
authors.lastname: Lee
authors.forename: Hee-Seung
authors.initials: HS
authors.lastname: Yang
authors.forename: Seok-Hwan
authors.initials: SH
authors.lastname: Park
authors.forename: Jae-Hee
authors.initials: JH
authors.lastname: Park
authors.forename: Changshin
authors.initials: C
authors.lastname: Sunwoo
authors.forename: Hwa-Won
authors.initials: HW
authors.lastname: Ryu
authors.forename: Doman
authors.initials: D
authors.lastname: Kim
authors.forename: Woo-Tae
authors.initials: WT
authors.lastname: Lee
authors.forename: Hae-Sung
authors.initials: HS
authors.lastname: Kim
authors.forename: Wol-Seog
authors.initials: WS
authors.lastname: Cha
authors.forename: Don-Hee
authors.initials: DH
authors.lastname: Park
mesh_terms: D005609:Free Radicals; D020100:Hydrogels / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011136:Polysorbates / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D020100:Hydrogels; D008689:Methacrylates; D011108:Polymers; D011136:Polysorbates