title: Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts.
abstract: Cinchona alkaloid derivatives modified to include a (thio)urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.
authors.affiliation: Centre for Synthesis and Chemical Biology, School of Chemistry, University of Dublin, Trinity College, Dublin 2, Ireland. connons@tcd.ie
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Connon