title: [Therapeutic strategy by manipulating some protease activities for Alzheimer's disease].
authors.affiliation: iwatan@brain.riken.jp
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Iwata
authors.forename: Makoto
authors.initials: M
authors.lastname: Higuchi
authors.forename: Takaomi C
authors.initials: TC
authors.lastname: Saido
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy* / Q000209:etiology*; D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors* / Q000502:physiology; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002118:Calcium / Q000502:physiology; D002154:Calpain / Q000037:antagonists & inhibitors* / Q000502:physiology; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D015260:Neprilysin / Q000378:metabolism / Q000502:physiology*; D010766:Phosphorylation; D013004:Somatostatin / Q000494:pharmacology / Q000627:therapeutic use*; D016875:tau Proteins / Q000378:metabolism
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D004791:Enzyme Inhibitors; D016875:tau Proteins; D013004:Somatostatin; D053829:Amyloid Precursor Protein Secretases; D002154:Calpain; D015260:Neprilysin; D002118:Calcium