title: An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation.
abstract: OBJECTIVE
  To develop a contemporary, evidence-based definition of premature ejaculation (PE).
  
  
  METHODS
  There are several definitions of PE; the most commonly quoted, the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders - 4th Edition - Text Revision, and other definitions of PE, are all authority-based rather than evidence-based, and have no support from controlled clinical and/or epidemiological studies. Thus in August 2007, the International Society for Sexual Medicine (ISSM) appointed several international experts in PE to an Ad Hoc Committee for the Definition of PE. The committee met in Amsterdam in October 2007 to evaluate the strengths and weaknesses of current definitions of PE, to critically assess the evidence in support of the constructs of ejaculatory latency, ejaculatory control, sexual satisfaction and personal/interpersonal distress, and to propose a new evidence-based definition of PE.
  
  
  RESULTS
  The Committee unanimously agreed that the constructs which are necessary to define PE are rapidity of ejaculation, perceived self-efficacy, and control and negative personal consequences from PE. The Committee proposed that lifelong PE be defined as a male sexual dysfunction characterized by ejaculation which always or nearly always occurs before or within about one minute of vaginal penetration, and the inability to delay ejaculation on all or nearly all vaginal penetrations, and negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy. This definition is limited to men with lifelong PE who engage in vaginal intercourse. The panel concluded that there are insufficient published objective data to propose an evidence-based definition of acquired PE.
  
  
  CONCLUSIONS
  The ISSM definition of lifelong PE represents the first evidence-based definition of PE. This definition will hopefully lead to the development of new tools and patient-reported outcome measures for diagnosing and assessing the efficacy of treatment interventions, and encourage ongoing research into the true prevalence of this disorder, and the efficacy of new pharmacological and psychological treatments.
authors.affiliation: Australian Center for Sexual Health, Sydney, Australia. cmcmahon@acsh.com.au
authors.forename: Chris G
authors.initials: CG
authors.lastname: McMahon
authors.forename: Stanley
authors.initials: S
authors.lastname: Althof
authors.forename: Marcel D
authors.initials: MD
authors.lastname: Waldinger
authors.forename: Hartmut
authors.initials: H
authors.lastname: Porst
authors.forename: John
authors.initials: J
authors.lastname: Dean
authors.forename: Ira
authors.initials: I
authors.lastname: Sharlip
authors.forename: P G
authors.initials: PG
authors.lastname: Adaikan
authors.forename: Edgardo
authors.initials: E
authors.lastname: Becher
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Broderick
authors.forename: Jacques
authors.initials: J
authors.lastname: Buvat
authors.forename: Khalid
authors.initials: K
authors.lastname: Dabees
authors.forename: Annamaria
authors.initials: A
authors.lastname: Giraldi
authors.forename: François
authors.initials: F
authors.lastname: Giuliano
authors.forename: Wayne J G
authors.initials: WJ
authors.lastname: Hellstrom
authors.forename: Luca
authors.initials: L
authors.lastname: Incrocci
authors.forename: Ellen
authors.initials: E
authors.lastname: Laan
authors.forename: Eric
authors.initials: E
authors.lastname: Meuleman
authors.forename: Michael A
authors.initials: MA
authors.lastname: Perelman
authors.forename: Raymond
authors.initials: R
authors.lastname: Rosen
authors.forename: David
authors.initials: D
authors.lastname: Rowland
authors.forename: Robert
authors.initials: R
authors.lastname: Segraves
mesh_terms: D004542:Ejaculation / Q000502:physiology*; D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D010549:Personal Satisfaction; D012735:Sexual Dysfunction, Physiological / Q000145:classification* / Q000175:diagnosis / Q000523:psychology; D013315:Stress, Psychological / Q000209:etiology; D009626:Terminology as Topic; D013997:Time Factors