Statement on guidance for genetic counseling in advanced paternal age.
In 1996, a practice guideline on genetic counseling for advanced paternal age was published. The current document updates the state of knowledge of advanced paternal age effects on single gene mutations, chromosome anomalies, and complex traits.
Toriello
Helga V
HV
Genetics Services, Spectrum Health, Grand Rapids, Michigan 49503-2528, USA. helga.toriello@spectrum-health.org
Meck
Jeanne M
JM
D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D005817:Genetic Counseling / Q000379:methods* / Q000592:standards*; D020022:Genetic Predisposition to Disease; D033142:Genetic Services / Q000592:standards; D005820:Genetic Testing / Q000592:standards; D017408:Guidelines as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D010331:Paternal Age; D012306:Risk