title: Adrenergic urticaria in a patient with anti-double-stranded DNA antibodies.
abstract: Adrenergic urticaria, a rare but distinct subtype of the physical urticarias, is characterized by wheals that are typically surrounded by a white halo of vasoconstriction, and by a positive response to intradermal adrenaline and noradrenaline injections. The pathogenesis of adrenergic urticaria is unknown. We report here a case of a 64-year-old woman with adrenergic urticaria who was found to have high levels of anti-double-stranded DNA antibodies without features of systemic lupus erythematosus. This is the first report associating adrenergic urticaria with anti-double-stranded DNA antibodies. The significance of this association is unknown.
authors.affiliation: Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Adele
authors.initials: A
authors.lastname: Chedraoui
authors.forename: Imad
authors.initials: I
authors.lastname: Uthman
authors.forename: Ossama
authors.initials: O
authors.lastname: Abbas
authors.forename: Samer
authors.initials: S
authors.lastname: Ghosn
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D004247:DNA / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D004837:Epinephrine; D005260:Female; D006801:Humans; D008875:Middle Aged; D009638:Norepinephrine; D011433:Propranolol / Q000627:therapeutic use; D013315:Stress, Psychological / Q000150:complications; D014581:Urticaria / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D014662:Vasoconstrictor Agents
chemical_list: D000974:Antibodies, Antinuclear; D000959:Antihypertensive Agents; D014662:Vasoconstrictor Agents; D004247:DNA; D011433:Propranolol; D009638:Norepinephrine; D004837:Epinephrine