title: Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses.
abstract: OBJECTIVE
  To determine outcome of Standardbred racehorses with moderate to severe midbody suspensory ligament desmitis (MSD) treated by means of ultrasound-guided intralesional injection of a single dose of platelet-rich plasma (PRP) followed by a program of gradually increased exercise.
  
  
  METHODS
  Nonrandomized clinical trial.
  
  
  METHODS
  9 Standardbred racehorses.
  
  
  METHODS
  Following injection of PRP, horses were allowed a controlled, gradual return to exercise. Race records for the year prior to injury and for 3 consecutive years after horses returned to racing were reviewed. For comparison purposes, race records of 9 Standardbred racehorses with no history of MSD racing at the same time were also reviewed.
  
  
  RESULTS
  All 9 horses with MSD returned to racing after treatment; median time to return to racing was 32 weeks. All 9 horses raced at least once during the first and second years after returning to racing, but only 5 raced during the third year. When number of starts, total earnings, and earnings per start were compared between case and comparison horses, the only significant differences were number of starts during the third year after case horses returned to racing and earnings per start during the first year after case horses returned to racing, with values being significantly lower for case horses than for comparison horses.
  
  
  CONCLUSIONS
  Results suggested that horses with moderate to severe MSD treated by means of intralesional injection of a single dose of PRP followed by a program of gradually increased exercise had an excellent prognosis for returning to racing.
authors.affiliation: Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Waselau
authors.forename: W Wesley
authors.initials: WW
authors.lastname: Sutter
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Genovese
authors.forename: Alicia L
authors.initials: AL
authors.lastname: Bertone
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D007249:Inflammation / Q000628:therapy / Q000662:veterinary*; D015552:Injections, Intralesional / Q000379:methods / Q000662:veterinary; D007794:Lameness, Animal; D008022:Ligaments / Q000473:pathology*; D008297:Male; D010805:Physical Conditioning, Animal; D010949:Plasma / Q000502:physiology; D012146:Rest; D016896:Treatment Outcome