Distribution of copper in rats submitted to treatment with copper aspirinate.
The distribution of copper in Sprague - Dawley rats following a three month oral administration of 0,10 or 50mg/kg copper aspirinate has been investigated. Metal content was determined by ICP - AES in blood, brain, kidney, liver, lung, spleen, and dejection. The results show that treatment with copper aspirinate did not cause accumulation of copper in rats and excess ingested copper was excreted through feces.
Liu
W
W
Institute of Precious Metals Kunming 650221 China.
Yang
Y
Y
Xiong
H
H
Lu
Y
Y
Yang
R
R