Meiotic maturation: receptor trafficking is the key.
Meiotic maturation and ovulation rates in Caenorhabditis elegans are regulated by a sperm-released gradient of major sperm protein (MSP). Recent work has provided insights into the modulation of the MSP signal by the trafficking of its receptor in oocytes.
Hang
Julie S
JS
Waksman Institute and Department of Genetics, Rutgers University, 190 Frelinghuysen Road, Piscataway, New Jersey 08854, USA.
Grant
Barth D
BD
Waksman Institute and Department of Genetics, Rutgers University, 190 Frelinghuysen Road, Piscataway, New Jersey 08854, USA.
Singson
Andrew
A
Waksman Institute and Department of Genetics, Rutgers University, 190 Frelinghuysen Road, Piscataway, New Jersey 08854, USA. Electronic address: singson@waksman.rutgers.edu.
D000818:Animals; D017173:Caenorhabditis elegans; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000378:metabolism*; D004705:Endocytosis / Q000502:physiology*; D005260:Female; D015801:Helminth Proteins / Q000378:metabolism*; D008297:Male; D008540:Meiosis / Q000502:physiology*; D009865:Oocytes / Q000378:metabolism / Q000502:physiology*; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism*
D029742:Caenorhabditis elegans Proteins; D018797:Cell Cycle Proteins; D015801:Helminth Proteins; C050602:major sperm protein, nematode; D020794:Receptor Protein-Tyrosine Kinases; C111040:vab-1 protein, C elegans