C825T G-protein beta3 subunit gene polymorphism, tilt test results and point score in syncopal patients.
We evaluated C825T polymorphism of the G-protein beta3 subunit gene in syncopal patients in regard to tilting results and the diagnostic point score (PS). In a multivariate analysis, only PS > or = -2 was associated with positive passive tilting (P < 0.05). The relationship between tilting results and this polymorphism needs further study.
Lelonek
Malgorzata
M
Department of Cardiology, Medical University of Lodz, Sterling Str. 1/3, 91-425 Lodz, Poland. mlelonek@poczta.fm
Pietrucha
Tadeusz
T
Matyjaszczyk
Monika
M
Goch
Jan Henryk
JH
D000328:Adult; D016022:Case-Control Studies; D004244:Dizziness / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D020962:Heterotrimeric GTP-Binding Proteins / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011237:Predictive Value of Tests; D013575:Syncope / Q000235:genetics*; D018667:Tilt-Table Test
C454420:G-protein beta3 subunit; D020962:Heterotrimeric GTP-Binding Proteins