Type I autoimmune hepatitis presenting with acute liver failure in the setting of wild mushroom ingestion.
Type I autoimmune hepatitis usually has an indolent presentation and course, and is classically thought of as a disease of young women, but can in fact occur across all age ranges. Although its etiology remains unclear, it is hypothesized that an environmental antigen may trigger the disease in a genetically susceptible individual. Here, we report the unusual case of a woman in her seventh decade who presented with acute liver failure as her initial manifestation of autoimmune hepatitis, and who had been a long-time ingestor of hand-picked, wild mushrooms.
Rogart
Jason N
JN
Department of Medicine, Section of Digestive, Yale University School of Medicine, New Haven, CT 06520-8019, USA.Jason.Rogart@yale.edu
Iyer
Anita
A
Robert
Marie E
ME
Levy
Gillian
G
Strazzabosco
Mario
M
D000363:Agaricales / Q000737:chemistry; D005260:Female; D019693:Hepatitis, Autoimmune / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008099:Liver / Q000473:pathology; D017114:Liver Failure, Acute / Q000209:etiology*; D008875:Middle Aged; D009145:Mushroom Poisoning