[Determination of meconium lead level of newborn by graphite furnace atomic absorption spectrometry].
To establish a method for the determination of lead in meconium from 144 samples of newborn through nitric acid digestion by means of graphite furnace atomic absorption spectrometry.


METHODS
after being baked for at least 12 h at 60 degrees C, 0.3 g of meconium was digested by nitric acid and hydrogen peroxide in turn at 80 degrees C under water-bath condition for 1h and then metered to the whole volume of to 2 mL. After correcting the background with D2 lamp, specimen basal corpuscle matched standard curve was used to detect the lead content.


RESULTS
The mean lead content of 93 experimental samples was 1.934 microg x g(-1) with the standard deviation (SD) of 1.551, and that of the 51 control samples was 1.012 microg x g(-1), with the SD of 1.084. There was a significant difference in lead levels of in meconnt between the experimental group and control group (p = 0.000).


CONCLUSIONS
The lead content of the experimental was significantly higher than that of the control group detected by this method. This method was stable and efficient.
Li
Yan
Y
Central Laboratory, Shantou University Medical College, Shantou 515031, China. liyan2005bo@163.com
Xu
Xi-Jin
XJ
Liu
Jun-Xiao
JX
Zheng
Liang-Kai
LK
Chen
Gang-Jian
GJ
Chen
Song-Jian
SJ
Huo
Xia
X
D006108:Graphite; D006801:Humans; D007231:Infant, Newborn; D007854:Lead / Q000032:analysis*; D008470:Meconium / Q000737:chemistry*; D013054:Spectrophotometry, Atomic / Q000379:methods*
D007854:Lead; D006108:Graphite