Development of an in silico coding gene SNP map in pigs.
A total of 5450 sequences obtained from the NCBI pig SNP database were consolidated into 465 unique sequences (189 singleton sequences and 276 contigs). These 465 sequences contained 1787 putative SNPs and had strong sequence homology to 433 human protein-coding genes based on blast analyses. These genes were assigned to the pig QTL maps (http://www.animalgenome.org/QTLdb/pig.html) via the human and pig comparative maps established by a pig radiation hybrid (RH) map. The SNP information characterized from this study provides a useful functional gene variation resource to facilitate QTL data mining in the pig genome.
Li
X P
XP
Department of Animal Science, Chungbuk National University, Cheongju, Korea.
Hu
Z L
ZL
Moon
S J
SJ
Do
K T
KT
Ha
Y K
YK
Kim
H
H
Byun
M J
MJ
Choi
B H
BH
Rothschild
M F
MF
Reecy
J M
JM
Kim
K S
KS
D000818:Animals; D020451:Contig Mapping; D030561:Databases, Nucleic Acid; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci; D021101:Radiation Hybrid Mapping; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid; D034421:Sus scrofa / Q000235:genetics*