title: Brainstem auditory evoked potentials in cattle sedated with xylazine.
abstract: This study examined the effect of sedation with xylazine on the brainstem auditory evoked potentials (BAEP) of cattle to determine whether sedation causes differences in waveform configuration, peak latencies, interpeak latencies, measurement time of the average count (2000 responses), and clinical signs. There were no significant differences between the sedation and no-sedation groups in peak latency of any stimulus intensities. In the sedation group, the baselines of waveforms were comparatively stabilized. Those in the no-sedation group were unstable, however, because the measurement can be influenced by excessive muscle movement. The present findings suggest that clinically, it is useful to use a sedative when measuring BAEP in cattle to control excessive movement of the cattle without influencing the peak latencies.
authors.affiliation: National Institute of Animal Health, Kannondai 3-1-5, Tsukuba 305-0856, Japan. sarai@affrc.go.jp
authors.forename: Shozo
authors.initials: S
authors.lastname: Arai
mesh_terms: D000161:Acoustic Stimulation; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D001933:Brain Stem / Q000187:drug effects / Q000502:physiology; D002417:Cattle / Q000502:physiology*; D018592:Cross-Over Studies; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects* / Q000502:physiology*; D005260:Female; D007700:Kinetics; D011897:Random Allocation; D013997:Time Factors; D014991:Xylazine / Q000494:pharmacology*
chemical_list: D000316:Adrenergic alpha-Agonists; D014991:Xylazine