title: Analysis of cerebrospinal fluid in healthy rabbits and rabbits with clinically suspected encephalitozoonosis.
abstract: Samples of uncontaminated cerebrospinal fluid (csf) were collected from the cisterna magna of 20 healthy laboratory rabbits and 21 pet rabbits with vestibular disease and/or paresis due to clinically suspected encephalitozoonosis. In the healthy rabbits' csf the leucocyte count was <or=4 leucocytes/microl (median 1.5 microl) and the concentration of protein ranged from 0.13 to 0.31 g/l (median 0.24 g/l). In the diseased rabbits, the number of leucocytes ranged from 1 to 87/microl (median 15/microl; P<0.001), and the concentration of protein ranged from 0.31 to 1.54 g/l (median 0.79 g/l; P<0.001); a cytological evaluation showed that they had greater numbers of lymphocytes and monocytes. It was concluded that encephalitozoonosis in rabbits is characterised by lymphomonocytic pleocytosis in CSF.
authors.affiliation: Clinic of Small Animal Medicine, Faculty of Veterinary Medicine, Ludwig Maximilian University Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Jass
authors.forename: K
authors.initials: K
authors.lastname: Matiasek
authors.forename: J
authors.initials: J
authors.lastname: Henke
authors.forename: H
authors.initials: H
authors.lastname: Küchenhoff
authors.forename: K
authors.initials: K
authors.lastname: Hartmann
authors.forename: A
authors.initials: A
authors.lastname: Fischer
mesh_terms: D000818:Animals; D000908:Antibodies, Fungal / Q000097:blood; D002555:Cerebrospinal Fluid / Q000166:cytology / Q000276:immunology / Q000382:microbiology*; D009670:Encephalitozoon cuniculi / Q000276:immunology / Q000302:isolation & purification; D016890:Encephalitozoonosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000401:mortality / Q000662:veterinary*; D007958:Leukocyte Count; D011817:Rabbits / Q000134:cerebrospinal fluid* / Q000382:microbiology; D012016:Reference Values; D014556:Urine / Q000382:microbiology
chemical_list: D000908:Antibodies, Fungal