title: A SERS-active nanocrystalline pd substrate and its nanopatterning leading to biochip fabrication.
abstract: Nanocrystalline metallic Pd films have been produced by thermolysis of Pd hexadecanethiolate deposited on a Si surface. The particle size was in the range of 50-60 nm based on electron and atomic force microscopy. The Pd surface produced was found to be surface-enhanced Raman scattering (SERS) active with an enhancement factor of approximately 10(5). The electron-resist behavior of Pd thiolate is exploited in conceptualizing a prototype chip with patterned Pd regions that are SERS active, called "SERS bits", which host different biomolecules.
authors.affiliation: Chemistry and Physics of Materials Unit and DST Unit on Nanoscience Jawaharlal Nehru Centre for Advanced Scientific Research Jakkur P O, Bangalore 560 064, India.
authors.forename: Thiruvelu
authors.initials: T
authors.lastname: Bhuvana
authors.forename: Giridhar U
authors.initials: GU
authors.lastname: Kulkarni
mesh_terms: D003460:Crystallization / Q000379:methods*; D056656:Lab-On-A-Chip Devices; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D046208:Microchip Analytical Procedures / Q000379:methods*; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D010165:Palladium / Q000737:chemistry*; D010316:Particle Size; D013059:Spectrum Analysis, Raman / Q000295:instrumentation / Q000379:methods*; D013499:Surface Properties
chemical_list: D046911:Macromolecular Substances; D010165:Palladium