Carbon tetrabromide-mediated carbon-sulfur bond formation via a sulfenyl bromide intermediate.
In the presence of carbon tetrabromide, a variety of dithiocarbamates, xanthates, dithioesters, and thioethers were prepared in one pot by reacting the corresponding dithioic acids or thiols with active methylene compounds/indole derivatives under mild conditions. The formation of a sulfenyl bromide intermediate is proposed as the key step, which initiates the C-S bond formation.
Tan
Jing
J
Department of Chemistry, Northeast Normal University, Changchun, China.
Liang
Fushun
F
Wang
Yeming
Y
Cheng
Xin
X
Liu
Qun
Q
Yuan
Hongjuan
H
D004952:Esters; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis; D015394:Molecular Structure; D013457:Sulfur Compounds / Q000737:chemistry*; D013859:Thiocarbamates / Q000138:chemical synthesis; D013871:Thiones / Q000138:chemical synthesis
D004952:Esters; D006842:Hydrocarbons, Brominated; D007211:Indoles; D013457:Sulfur Compounds; D013859:Thiocarbamates; D013871:Thiones; C031387:carbon tetrabromide