title: Gold(I)-catalyzed divergence in the reactivity of 3-silyloxy 1,6-enynes: pinacol-terminated vs claisen-terminated cyclization cascades.
abstract: On activation with catalytic amounts of gold(I) complexes, 3-silyloxy 1,6-enynes can react through two alternative pathways. In one, a cascade reaction consisting of carbocyclization and subsequent pinacol rearrangement takes place. In the second pathway, a heterocyclization is followed by a Claisen rearrangement. The reaction outcome differs depending on the substitution pattern of the 3-silyloxy 1,6-enynes and, more importantly, the electronic properties of the gold-bound phosphane ligand.
authors.affiliation: Department of Chemistry, POSTECH, Pohang, Republic of Korea.
authors.forename: Baburaj
authors.initials: B
authors.lastname: Baskar
authors.forename: Hyo J
authors.initials: HJ
authors.lastname: Bae
authors.forename: Sang E
authors.initials: SE
authors.lastname: An
authors.forename: Jae Y
authors.initials: JY
authors.lastname: Cheong
authors.forename: Young H
authors.initials: YH
authors.lastname: Rhee
authors.forename: Alexander
authors.initials: A
authors.lastname: Duschek
authors.forename: Stefan F
authors.initials: SF
authors.lastname: Kirsch