Endosulfan and other organochlorine pesticide residues in maternal and cord blood in North Indian population.
Humans are exposed to various environmental chemicals such as organochlorine pesticide residues, heavy metals, polychlorinatedbiphenyls (PCBs) etc. There is paucity of data regarding the present blood levels of organochlorine residues in North Indian population with reference to reproductive health. The present study was designed to analyze the levels of organochlorine pesticide residues in maternal and cord blood samples of normal healthy women with full term pregnancy to gain insight into the current status of pesticide burden in newborns. Hexachlorocyclohexane (HCH) contributed maximum towards the total organochlorine residues present in maternal and cord blood followed by endosulfan, pp' DDE and pp' DDT being the least. This is also the first report indicating endosulfan levels in this population. Our data indicates a transfer rate of 60-70% of these pesticides from mothers to newborns and this high rate of transfer of pesticides is of great concern as it may adversely affect the growth and development of newborn.
Pathak
Rahul
R
Department of Biochemistry, University College of Medical Sciences, Dilshad Garden, Delhi, 110 095, India.
Suke
Sanvidhan G
SG
Ahmed
Rafat S
RS
Tripathi
A K
AK
Guleria
Kiran
K
Sharma
C S
CS
Makhijani
S D
SD
Mishra
Meenu
M
Banerjee
B D
BD
D000328:Adult; D004726:Endosulfan / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007306:Insecticides / Q000097:blood*; D010573:Pesticide Residues / Q000097:blood*; D011247:Pregnancy
D007306:Insecticides; D010573:Pesticide Residues; D004726:Endosulfan