title: Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy.
abstract: OBJECTIVE
  The intent of this study was to determine the efficacy and tolerance of single dose oral cefixime use in the treatment of pregnant women with endocervical gonococcal carriage.
  
  
  METHODS
  A retrospective review of clinic records over a 3 year period identified patients treated with a single 400 mg dose of cefixime for gonorrhea during pregnancy. Side effects and subsequent gonococcal carriage were noted.
  
  
  RESULTS
  Pregnant women (n = 102) treated with cefixime were reviewed. A cure rate of 95.2% was found. Side effects were reported in three patients: two had nausea and vomiting and one had diarrhea.
  
  
  CONCLUSIONS
  A single 400 mg oral dose of cefixime was effective for the treatment of gonorrhea and was well tolerated by the pregnant women.
authors.affiliation: Department of Obstetrics and Gynecology Louisiana State University Medical Center 1542 Tulane Avenue New Orleans LA USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Miller