title: [Kidney function and immunosuppression of kidney-transplanted patients].
abstract: BACKGROUND
  The number of kidney-transplanted patients is growing. This report describes the age, sex distribution, kidney function, graft age, and immunosuppressive drugs of kidney-transplanted patients followed at the outpatient clinic of the nephrology department at Copenhagen University Hospital, Herlev, Denmark.
  
  
  METHODS
  Cross-sectional study of all living kidney-transplanted patients with a functioning graft followed at Copenhagen University Hospital, Herlev (n=241). Data were extracted from patient records during November 2005-March 2006.
  
  
  RESULTS
  The sex distribution (131 males, 110 females) was equal. The average patient age was 52 years (SD 12), the average glomerular filtration rate 43 ml/min/1.73 m2 (range 6-114 ml/min/1.73 m2), and the average graft age was 8.3 years (range 0-28 years). Hyperparathyroidism was highly prevalent (64%). The majority of patients (74%) were treated with triple-drug immunosuppression, in most cases (46%) with the combination prednisolone-ciclosporine-azathioprine. During recent years, azathioprine has been increasingly replaced by mycophenolate mofetil.
  
  
  CONCLUSIONS
  The majority of kidney-transplanted patients with a functioning graft have sufficient kidney function to keep the patients free of uremic symptoms. Hyperparathyroidism is frequent. The immunosuppressive regimens used for kidney-transplanted patients are currently changing.
authors.affiliation: Herlev Hospital, Nefrologisk Afdeling, Herlev.
authors.forename: Anne Mette
authors.initials: AM
authors.lastname: Frederiksen
authors.forename: Jesper Melchior
authors.initials: JM
authors.lastname: Hansen
authors.forename: Bettina
authors.initials: B
authors.lastname: Ewers
authors.forename: Ane
authors.initials: A
authors.lastname: Gasbjerg
authors.forename: Peter
authors.initials: P
authors.lastname: Marckmann
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage; D003430:Cross-Sectional Studies; D016572:Cyclosporine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D016030:Kidney Transplantation / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone; D001379:Azathioprine