title: Pyronane monoterpenoids from the fruit of Gardenia jasminoides.
abstract: Five new pyronane-type monocyclic monoterpenoids, jasminodiol (1), jasminoside H (6), 6'-O-sinapoyljasminoside A (7), 6'-O-sinapoyljasminoside C (8), and jasminoside I (9), together with four known analogues, were isolated from the fruit of Gardenia jasminoides. The structures of the new metabolites were characterized using spectroscopic data, and the absolute configurations of 1, 6, and 7 were established using circular dichroism (CD) analysis. Compound 1 showed tyrosinase inhibitory activity (IC 50 2.2 mM).
authors.affiliation: College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea.
authors.forename: Quan Cheng
authors.initials: QC
authors.lastname: Chen
authors.forename: UiJoung
authors.initials: U
authors.lastname: Youn
authors.forename: Byung-Sun
authors.initials: BS
authors.lastname: Min
authors.forename: KiHwan
authors.initials: K
authors.lastname: Bae
mesh_terms: D000363:Agaricales / Q000201:enzymology; D002942:Circular Dichroism; D004305:Dose-Response Relationship, Drug; D005638:Fruit / Q000737:chemistry; D032062:Gardenia / Q000737:chemistry*; D007723:Korea; D007980:Levodopa / Q000494:pharmacology; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors*; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: C530892:6'-O-sinapoyljasminoside A; C530893:6'-O-sinapoyljasminoside C; D039821:Monoterpenes; C530890:jasminodiol; C530891:jasminoside H; C530894:jasminoside I; D007980:Levodopa; D014442:Monophenol Monooxygenase