title: Intradural extracerebral choristoma. Case report and review of the literature.
abstract: BACKGROUND
  Intracranial extracerebral neuroglial choristoma is a very rare entity. A cleft palate or a nasopharyngeal teratoma has been described as accompanying choristoma, but there are no observations of both anomalies being simultaneously present and combined.
  
  
  METHODS
  An 8-month-old girl presented with seizures, without evidence of any other neurological abnormalities. Brain magnetic resonance imaging demonstrated a 2.0-cm-sized, round-shaped mass in the frontal midline. The T(1)- and T(2)-weighted images showed a well-circumscribed iso-signal intensity lesion with no gadolinium enhancement.
  
  
  RESULTS
  Surgical exploration revealed a yellowish tumor mass with whitish soft tissue material within the tumor, adherence to the surrounding blood vessels, and therefore subtotal removal was performed. Pathologic examination was neuroglial choristoma with 1.5% of MIB-1 labeling index. The patient also had a cleft palate with a pinkish palatal mass and underwent repair of the cleft palate, and excision of mass that was a mature cystic teratoma on pathologic examination. Follow-up at 18 months later showed that there was no evidence of tumor regrowth or neurological deficit, and the neurological development was normal.
  
  
  CONCLUSIONS
  The authors described a rare case of intracranial extracerebral neuroglial choristoma accompanied by both nasopharyngeal teratoma and cleft palate and suggested its benign nature from the low MIB-1 labeling index.
authors.affiliation: Department of Neurosurgery, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Jung Eon
authors.initials: JE
authors.lastname: Park
authors.forename: Myong Chul
authors.initials: MC
authors.lastname: Park
authors.forename: Soo Han
authors.initials: SH
authors.lastname: Yoon
authors.forename: Jang Hee
authors.initials: JH
authors.lastname: Kim
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002828:Choristoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002972:Cleft Palate / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D009303:Nasopharyngeal Neoplasms / Q000150:complications; D009457:Neuroglia; D013724:Teratoma / Q000150:complications