title: [Comparison of two antibioprophylaxis protocols in ear surgery].
abstract: BACKGROUND
  During surgical procedure, antibioprophylaxis is known to decrease bacterial proliferation and limit postoperative complications such as infections. In France, antibiotic prescription guidelines have been established for ear surgery, but applied with discrepancies. The purpose of the study was to evaluate the necessity of antibioprophylaxis in ear surgery.
  
  
  METHODS
  Retrospective study of two consecutives series of ear surgery with two different antibioprophylaxis protocols. In the first series (n=100), antibioprophylaxis by amoxicillin and clavulanic acid was given only in cases of chronic otitis media with otorrhea and cholesteatoma (contaminated surgery). In the second series (n=107), no antibiotic was administered. The number of infected complications was evaluated by reviewing medical charts.
  
  
  RESULTS
  The percentage of infected complications was 5% versus 6.5% in the second series (with no antibioprophylaxis), for all types of ear surgery, 9.4% versus 4.2% after ear contaminated surgery. No statistical difference was observed between the two series.
  
  
  CONCLUSIONS
  In ear surgery, postoperative infected complications do not more frequently occur without antibioprophylaxis, either in otorrhea or in cholesteatoma surgery.
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Bertrand
authors.forename: J-F
authors.initials: JF
authors.lastname: Mangez
authors.forename: O
authors.initials: O
authors.lastname: Choussy
authors.forename: D
authors.initials: D
authors.lastname: Dehesdin
authors.forename: J-P
authors.initials: JP
authors.lastname: Marie
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D002558:Cerebrospinal Fluid Otorrhea / Q000150:complications; D018424:Cholesteatoma, Middle Ear / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000150:complications / Q000601:surgery*; D013506:Otologic Surgical Procedures; D011300:Preoperative Care
chemical_list: D019980:Amoxicillin-Potassium Clavulanate Combination