Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae.
The twin-Cx(9)C motif protein Pet191 is essential for cytochrome c oxidase maturation. The motif Cys residues are functionally important and appear to be present in disulfide linkages within a large oligomeric complex associated with the mitochondrial inner membrane. The import of Pet191 differs from that of other twin-Cx(9)C motif class of proteins in being independent of the Mia40 pathway.
Khalimonchuk
Oleh
O
University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
Rigby
Kevin
K
Bestwick
Megan
M
Pierrel
Fabien
F
Cobine
Paul A
PA
Winge
Dennis R
DR
D020816:Amino Acid Motifs; D003576:Electron Transport Complex IV / Q000096:biosynthesis / Q000378:metabolism*; D004734:Energy Metabolism / Q000235:genetics; D015966:Gene Expression Regulation, Fungal / Q000235:genetics; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism / Q000648:ultrastructure; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics
D008565:Membrane Proteins; C532451:Pet191 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D003576:Electron Transport Complex IV