title: Direct ortho-acetoxylation of anilides via palladium-catalyzed sp(2) C-H bond oxidative activation.
abstract: Various anilides have been directly ortho-acetoxylated through a Pd(OAc)2-catalyzed C-H bond activation process. The amide group in anilides was found to functionalize as an elegant directing group to convert aromatic sp(2) C-H bonds into C-O bonds in high regioselectivity with acetic acid as the acetate source and K(2)S(2)O(8) as the oxidant.
authors.affiliation: Hefei National Laboratory for Physical Sciences at Microscale, Joint Laboratory of Green Synthetic Chemistry, and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, PR China. gwang@ustc.edu.cn
authors.forename: Guan-Wu
authors.initials: GW
authors.lastname: Wang
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Yuan
authors.forename: Xue-Liang
authors.initials: XL
authors.lastname: Wu