title: Long-term outcome and risk factors of failure after bile duct injury repair.
abstract: BACKGROUND
  The real long-term outcome of a hepaticojejunostomy (HJ) to repair bile duct injury (BDI) is unclear, and the risk factors for repair failure are partially defined.
  
  
  METHODS
  A retrospective, nonrandomized study of the long-term outcome of biliary reconstructions after major BDIs. All injuries occurred in association with cholecystectomy.
  
  
  RESULTS
  Twenty-nine patients were referred with complete transection of the common (n = 16), right (n = 5), or right sectoral (n = 4) hepatic ducts or of >1 major duct (n = 4) between October 2002 and January 2007. Mean follow-up was 24 months, range 12-60 months. Original repairs were "immediate" in 14, "delayed" (within 24-72h) in 5, and "elective" (after >8 weeks) in 10, and strictures developed in 9, 5, and 1 of those HJs, respectively. The surgical outcomes were significantly better when the intervention took place electively (p = 0.003). Original HJ repairs were done by a hepatobiliary surgeon (n = 23) or by a general surgeon (n = 6): the outcome was significantly better for the former (p < 0.001).
  
  
  CONCLUSIONS
  The 51.7% incidence of strictures after BDI repair in this study was higher than reported in the literature, probably because of selection bias secondary to the referral pattern. The timing of repair and the surgeon's expertise are significant risk factors of failure.
authors.affiliation: Hepatobiliary Surgery Unit, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Yaacov
authors.initials: Y
authors.lastname: Goykhman
authors.forename: Issac
authors.initials: I
authors.lastname: Kory
authors.forename: Risa
authors.initials: R
authors.lastname: Small
authors.forename: Ada
authors.initials: A
authors.lastname: Kessler
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Klausner
authors.forename: Richard
authors.initials: R
authors.lastname: Nakache
authors.forename: Menahem
authors.initials: M
authors.lastname: Ben-Haim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000713:Anastomosis, Roux-en-Y / Q000379:methods; D001652:Bile Ducts / Q000293:injuries* / Q000601:surgery*; D002763:Cholecystectomy / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications; D007582:Jejunostomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D012307:Risk Factors; D017211:Treatment Failure