Synthesis of eudistomin C and E: improved preparation of the indole unit.
An improved synthesis of the indole unit, a key intermediate for eudistomin C, was established utilizing Makosza's indole synthesis. A concise total synthesis of eudistomin E was achieved on the basis of the improved synthesis.
Yamagishi
Hiroaki
H
Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
Matsumoto
Koji
K
Iwasaki
Kotaro
K
Miyazaki
Tohru
T
Yokoshima
Satoshi
S
Tokuyama
Hidetoshi
H
Fukuyama
Tohru
T
D000818:Animals; D002243:Carbolines / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D014561:Urochordata / Q000737:chemistry
D002243:Carbolines; D007211:Indoles; C507825:eudistomin C; C076219:eudistomin E