title: Distribution of rhodium in mice submitted to treatment with the adduct of rhodium propionate and sodium isonicotinate.
abstract: The distribution of rhodium in Balb/c mice following intraperitoneal (ip) administration of a solution of adduct of rhodium propionate and sodium isonicotinate has been investigated. The metal concentration was determined in blood and in the following organ tissues: brain, heart, lung, liver, spleen, kidney, testes, and uterus/ovary, and the rhodium concentration was obtained by Inductively Coupled Argon Atomic Emission Spectroscopy (ICP-AES). The metal was detected in all organ tissues examined, mainly in spleen, liver, uterus/ovary and heart. Nine days after the injection, traces of rhodium were found in the liver and kidneys and, twenty days after the injection, only in the liver.
authors.affiliation: Instituto de Química USP C.P. 26.077 São Paulo SP 05599-970 Brazil.
authors.forename: A R
authors.initials: AR
authors.lastname: de Souza
authors.forename: R
authors.initials: R
authors.lastname: Najjar
authors.forename: E
authors.initials: E
authors.lastname: de Oliveira
authors.forename: S B
authors.initials: SB
authors.lastname: Zyngier