title: Long, uniform Lactobacilli (Döderlein's Bacteria): a new risk factor for postoperative infection after first-trimester abortion.
abstract: OBJECTIVE
  The production of hydrogen peroxide (H2O2) from different strains of lactobacilli in the vagina has been proposed to play one of the most important protective roles in the vaginal defense system. New data have, however, suggested that Döderlein's bacteria, with the morphological appearance of long lactobacilli, have a low production of H2O2 . The purpose of the present study was to correlate the morphology of lactobacilli with the incidence of infection following legal abortion.
  
  
  METHODS
  Seven hundred sixty-nine women with lactobacilli but without Chlamydia trachomatis or bacterial vaginosis in their vaginal wet smears who were to undergo legal abortions were divided into 6 different groups according to the morphological appearance of the lactobacilli. The postoperative infection rates in these different groups were compared. A phenotypic classification of some of the lactobacilli was performed.
  
  
  RESULTS
  The presence of Döderlein's bacteria compared with a mixed flora of lactobacilli increased the risk of postoperative infection 3 times [relative risk (RR) = 3.0; 95% confidence interval (CI), 1.5-6.3]. After a logistic regression analysis, the only independent risk factors were the presence of Döderlein's bacteria and earlier gestational age.
  
  
  CONCLUSIONS
  We found that the lactobacilli regarded as commensal organisms and "normal, healthy lactobacilli" in the vagina were present in only 18% of these women and that their presence might be hazardous. Therefore, we must reconsider our concept of the "normal" lactobacilli in the vaginal wet smears of healthy women.
authors.affiliation: Department of Obstetrics and Gynaecology University of Gothenburg Gothenburg Sweden.
authors.forename: J J
authors.initials: JJ
authors.lastname: Platz-Christensen
authors.forename: C
authors.initials: C
authors.lastname: Påhlson
authors.forename: P G
authors.initials: PG
authors.lastname: Larsson