title: Race and diet interactions in the acquisition, maintenance, and loss of bone.
abstract: Racial differences in bone become apparent during puberty. Studies of areal bone mineral density (aBMD) generally show the greatest aBMD in African Americans followed by American white, Hispanic, and Native Americans, with the least aBMD in Asian Americans. Racial differences in fracture risk, however, do not exactly follow racial variation in aBMD. These group differences in bone mass are largely explained by differences in bone size, although calcium intake and physical activity are also significant predictors of aBMD and bone mineral content. Racial differences in calcium metabolism, as influenced by calcium and sodium intake, explain much of the black vs. white differences in skeletal calcium accretion during puberty. The relative importance of calcium and sodium in calcium metabolism has not yet been elucidated among Asians. Predictors of aBMD have been reported for African American and American white adults and predictors of aBMD in Chinese American women have recently been studied. Much remains to be studied regarding interactions between race and diet.
authors.affiliation: Division of Endocrinology, Metabolic Bone Disease Unit, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
authors.forename: Marcella D
authors.initials: MD
authors.lastname: Walker
authors.forename: Rachel
authors.initials: R
authors.lastname: Novotny
authors.forename: John P
authors.initials: JP
authors.lastname: Bilezikian
authors.forename: Connie M
authors.initials: CM
authors.lastname: Weaver
mesh_terms: D001835:Body Weight; D015519:Bone Density / Q000187:drug effects / Q000235:genetics* / Q000502:physiology*; D004032:Diet; D005260:Female; D050723:Fractures, Bone; D006801:Humans; D008019:Life Style; D008297:Male; D010024:Osteoporosis; D044469:Racial Groups; D012307:Risk Factors; D014481:United States