title: Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate.
abstract: Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded bla(OXA-58) gene that was 100% homologous to the same gene in Acinetobacter baumannii.
authors.affiliation: Servei de Microbiologia, Centre de Diagnóstic Biomèdic, Hospital Clínic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Marti
authors.forename: Javier
authors.initials: J
authors.lastname: Sánchez-Céspedes
authors.forename: M Dolores
authors.initials: MD
authors.lastname: Blasco
authors.forename: Marc
authors.initials: M
authors.lastname: Ruiz
authors.forename: Paula
authors.initials: P
authors.lastname: Espinal
authors.forename: Verónica
authors.initials: V
authors.lastname: Alba
authors.forename: Felipe
authors.initials: F
authors.lastname: Fernández-Cuenca
authors.forename: Alvaro
authors.initials: A
authors.lastname: Pascual
authors.forename: Jordi
authors.initials: J
authors.lastname: Vila
mesh_terms: D000150:Acinetobacter / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D000151:Acinetobacter Infections / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D015780:Carbapenems / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015780:Carbapenems; D015378:Imipenem; D001618:beta-Lactamases; C509061:beta-lactamase OXA-58, Acinetobacter junii