Oncocytic and oncocyte-like lesions of the head and neck.
An oncocyte is a cell containing an abundant amount of deeply eosinophilic finely granular cytoplasm, rounded nuclei, and variable presence of nucleoli in conventional hematoxylin-eosin-stained sections. In the head and neck, a small number of lesions are constructed overwhelmingly of oncocytes; a larger number of nononcocytic lesions composed of cells that imitate this morphology are also encountered. Correlating the fine-needle aspiration cytology and histology of both oncocytic and oncocyte-like neoplasms can assist in avoiding interpretive pitfalls among these lesions.
Wakely
Paul E
PE
Department of Pathology, Ohio State University, College of Medicine, Columbus, OH 43210, USA. paul.wakely@osumc.edu
D018249:Adenoma, Oxyphilic / Q000473:pathology; D044963:Biopsy, Fine-Needle; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D024862:Oxyphil Cells / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology