title: Changing trends in intracranial abscesses secondary to ear and sinus disease.
abstract: OBJECTIVE
  To review the management, causative organisms, morbidity and mortality of intracranial abscesses secondary to sinus and ear disease.
  
  
  METHODS
  Retrospective, case note review of suppurative intracranial complications of ear and sinus disease in patients admitted to a regional neurosurgical centre between 1980 and 2004. These data were compared with published material from the same region from 1950-1979.
  
  
  RESULTS
  There was a marked reduction in the mortality rate and the number of intracranial abscesses secondary to chronic ear disease, comparing the two time periods. However, there was little change in the percentage of sinus-related abscesses treated and in their symptoms, signs, abscess location and long term morbidity. Microbiology results showed that streptococcal species predominated as causative organisms, with a high percentage of anaerobic bacteria in otogenic abscesses.
  
  
  CONCLUSIONS
  Despite improved outcomes, a high index of suspicion for intracranial complications of ear or sinus disease should be maintained in the presence of appropriate signs and symptoms.
authors.affiliation: Department of Otolaryngology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK. sank.tandon@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Tandon
authors.forename: N
authors.initials: N
authors.lastname: Beasley
authors.forename: A C
authors.initials: AC
authors.lastname: Swift
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001922:Brain Abscess / Q000188:drug therapy / Q000209:etiology* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D004427:Ear Diseases / Q000150:complications*; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010254:Paranasal Sinus Diseases / Q000150:complications*; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology* / Q000401:mortality; D016896:Treatment Outcome; D055815:Young Adult