Schistosomiasis and hepatic fibrosis regression.
Manson schistosomiasis is an important cause of hepatic fibrosis, a consequence of the highly fibrogenic nature of the mature schistosome eggs, the main pathogenetic factor of that disease. Thus, students interested on schistosomiasis are to be also interested on the subject of fibrosis formation and degradation since the very beginning of their studies. A brief review of the studies directly related to such interest is presented here to stress the progress obtained, and to point out to the need of further research.
Andrade
Zilton A
ZA
Laboratory of Experimental Pathology, Gonçalo Moniz Research Center/FIOCRUZ, 40295001 Salvador, BA, Brazil. zilton@cpqgm.fiocruz.br
D000818:Animals; D006801:Humans; D008103:Liver Cirrhosis / Q000469:parasitology* / Q000473:pathology; D012547:Schistosoma / Q000502:physiology*; D012552:Schistosomiasis / Q000150:complications*