title: Echo-guided percutaneous coil embolization of a symptomatic massive metastasis of a renal cell carcinoma in the right ventricular outflow tract.
abstract: We present the case of a 41-year-old woman who was admitted to our centre with progressive symptoms of congestive heart failure (NYHA class III) 5 years after a radical nephrectomy for renal cell carcinoma. Magnetic resonance imaging demonstrated a 5 x 3 cm homogeneous intracardial mass causing right ventricular outflow tract obstruction, not accessible to surgical resection. Serial echo-guided, percutaneous coil embolization of the cardial metastasis was performed with Contour SE Microparticles (150-250 or 300-500 microm) after identification of the target region of the metastasis by contrast injection (Levovist) through the balloon catheter into the coronary artery under transoesophageal echocardiographic control prior to induction of the necrosis, corresponding to the technique which has been described for septal ablation in hypertrophic obstructive cardiomyopathy. Follow-up after serial embolization showed a good haemodynamic and a marked clinical response (dyspnoea NYHA I-II) which lasted during the 19 month of survival after the index procedure.
authors.affiliation: Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Georgstr 11, D-32545 Bad Oeynhausen, Germany. thomas.butz@marienhospital-herne.de
authors.forename: T
authors.initials: T
authors.lastname: Butz
authors.forename: H K
authors.initials: HK
authors.lastname: Schmidt
authors.forename: D
authors.initials: D
authors.lastname: Fassbender
authors.forename: H
authors.initials: H
authors.lastname: Esdorn
authors.forename: M
authors.initials: M
authors.lastname: Wiemer
authors.forename: D
authors.initials: D
authors.lastname: Horstkotte
authors.forename: L
authors.initials: L
authors.lastname: Faber
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000556:secondary*; D002404:Catheterization; D004452:Echocardiography; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006338:Heart Neoplasms / Q000150:complications* / Q000556:secondary / Q000628:therapy*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D014694:Ventricular Outflow Obstruction / Q000209:etiology* / Q000628:therapy*