Control of final seed and organ size by the DA1 gene family in Arabidopsis thaliana.
Although the size of an organism is a defining feature, little is known about the mechanisms that set the final size of organs and whole organisms. Here we describe Arabidopsis DA1, encoding a predicted ubiquitin receptor, which sets final seed and organ size by restricting the period of cell proliferation. The mutant protein encoded by the da1-1 allele has a negative activity toward DA1 and a DA1-related (DAR) protein, and overexpression of a da1-1 cDNA dramatically increases seed and organ size of wild-type plants, identifying this small gene family as important regulators of seed and organ size in plants.
Li
Yunhai
Y
Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom. yhli@genetics.ac.cn
Zheng
Leiying
L
Corke
Fiona
F
Smith
Caroline
C
Bevan
Michael W
MW
D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D029681:Arabidopsis Proteins / Q000235:genetics / Q000502:physiology*; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics / Q000502:physiology; D004742:Enhancer Elements, Genetic; D035264:Flowers / Q000235:genetics / Q000254:growth & development; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant / Q000502:physiology; D018525:Germination / Q000235:genetics; D060588:LIM Domain Proteins; D005810:Multigene Family / Q000502:physiology; D009929:Organ Size / Q000235:genetics*; D030821:Plants, Genetically Modified; D011401:Promoter Regions, Genetic; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology*; D012639:Seeds / Q000254:growth & development*
D029681:Arabidopsis Proteins; C529975:DA1 protein, Arabidopsis; D018076:DNA, Complementary; D060588:LIM Domain Proteins; D011956:Receptors, Cell Surface