[Multi-center randomized clinical study on Shenqi-fuzheng injection combined with chemotherapy in the treatment for lung cancer].
OBJECTIVE
To investigate the effect of Shenqi-fuzheng injection combined with chemotherapy on the quality of life in lung cancer patient.


METHODS
232 pathologically confirmed nonsmall cell lung cancer patients were enrolled into this multi-center randomized trial. Of these 232 patients, 116 cases were treated with chemotherapy alone (chemotherapy group), another 116 with chemotherapy combined with Shenqi-fuzheng injection produced by Lizhu Company (Shenqi-fuzheng group). Life quality of these patients were evaluated using the QOL scale of European Organization for Research on Treatment of Cancer (QLQ-C30) and the functional living index-cancer.


RESULTS
Compared with chemotherapy group, Life quality and symptoms were improved in the Shenqi-fuzheng group, which including lassitude, deficient in breath, pain, fullness in chest and hypochondrium, excessive phlegm, cough, complexion whiteness. Response rate to chemotherapy was also improved. No AE and SAE were observed in the Shenqi-fuzheng group.


CONCLUSIONS
Shenqi-fuzheng injection combined with chemotherapy is safe and effective in the treatment for non-small cell lung cancer.
Lin
Hong-Sheng
HS
Department of Medical Oncology, Guanganmen Hospital, China Academy of Chinese Traditional Medicine, Beijing 100053, China.
Li
Dao-Rui
DR
D000293:Adolescent; D000328:Adult; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000503:physiopathology; D002945:Cisplatin / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D017239:Paclitaxel; D008517:Phytotherapy; D011788:Quality of Life; D043823:Taxoids / Q000627:therapeutic use; D055815:Young Adult
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D043823:Taxoids; C521737:shenqi fuzheng; D017239:Paclitaxel; D002945:Cisplatin