title: Periprosthetic mineralization changes around femoral stems: a prospective 12-month study with DEXA.
abstract: OBJECTIVE
  The objective was to evaluate bone mineral density (BMD) changes around the proximal femur after implantation of two different anatomical stems.
  
  
  METHODS
  Thirty-six patients (19 women and 17 men) who underwent total hip replacement were recruited. A Bihapro stem was implanted in 23 patients (with a mean age of 60.9 years) and a Citation stem in 13 patients (with a mean age of 59.7 years). All patients underwent serial radiography of the affected hip (follow-up time: 12 months). Baseline periprosthetic and overall BMD were measured with dual-energy X-ray absorptiometry (DEXA) 1 week and 12 months after hip replacement. Regions of interest (ROIs) were defined according to Gruen's system (ROIs 1-7).
  
  
  RESULTS
  All stems were classified as radiographically stable. Bone ongrowth (spot welds) was present in zones 1 and 2 in all patients with the Bihapro stem. The distribution of baseline densities was very similar in the two groups of patients. In Bihapro implants a significant increment of mineralisation was present in ROI 1 after 1 year; ROIs 2 to 7 showed no density variation. The following observations were made regarding the Citation implants: no increment in density was shown in ROI 1; the differences in densities among the ROIs were significant after 1 year in the global evaluation (p = 0.004); the comparison between the single ROIs showed decalcification in ROIs 2 and 7 and a density increment in ROI 5.
  
  
  CONCLUSIONS
  Bihapro stems appear to achieve adequate proximal fixation, avoiding the "stress shielding" phenomenon.
authors.affiliation: Department of Orthopaedics, School of Medicine, Catholic University, Largo A. Gemelli 1, 00168, Rome, Italy. dottorgalli@yahoo.it
authors.forename: Marco
authors.initials: M
authors.lastname: Galli
authors.forename: Antonio
authors.initials: A
authors.lastname: Leone
authors.forename: Francesco Ciro
authors.initials: FC
authors.lastname: Tamburrelli
authors.forename: Tommaso
authors.initials: T
authors.lastname: Pirronti
authors.forename: Angelo Gabriele
authors.initials: AG
authors.lastname: Aulisa
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D019644:Arthroplasty, Replacement, Hip; D015519:Bone Density / Q000502:physiology*; D016723:Bone Remodeling / Q000502:physiology*; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging* / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018709:Statistics, Nonparametric