Fine needle aspiration findings in angiofollicular hyperplasia with eosinophilia: a case report.
BACKGROUND
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon vascular inflammatory lesion usually involving the dermis or subcutaneous tissue of the head-neck region of middle-aged women. Histologically, this lesion shows a florid proliferation of vessels lined by particular endothelial cells and an inflammatory infiltrate composed of lymphocytes and eosinophils.


METHODS
A 30-year-old woman presented with multiple periauricular skin nodules. Fine needle aspiration cytology shows a mixed population of lymphoid cells with an admixture of eosinophils and large cells with vesicular nuclei and prominent nucleoli. A diagnosis of AHLE was confirmed on histopathologic examination.


CONCLUSIONS
Various conditions, both benign and malignant, may mimic Kimura's disease clinically and on smears. These must be ruled out before making a diagnosis of Kimura's disease. The cytologic features of Kimura's disease have to be interpreted in the appropriate clinical setting in order to make a correct preoperative diagnosis.
Azarpira
Negar
N
Department of Pathology, Shiraz Medical School, Shiraz, Iran. negarazarpira@yahoo.com
Ashraf
Mohamad Javad
MJ
Shishegar
Mahmood
M
D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology*; D044963:Biopsy, Fine-Needle; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D004423:Ear; D004804:Eosinophils / Q000473:pathology; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology