title: Perceptions of quality-of-life effects of treatments for diabetes mellitus in vulnerable and nonvulnerable older patients.
abstract: OBJECTIVE
  To assess whether patient perceptions of treatments for diabetes mellitus differ according to clinical criteria such as limited life expectancy and functional decline (i.e., vulnerability).
  
  
  METHODS
  Cross-sectional survey.
  
  
  METHODS
  Clinics affiliated with two Chicago-area hospitals.
  
  
  METHODS
  Patients aged 65 and older living with type 2 diabetes mellitus (N=332).
  
  
  METHODS
  Utilities (quantitative measures of preference on a scale from 0 to 1, with 0 representing a state equivalent to death and 1 representing life in perfect health) were assessed for nine hypothetical treatment states using time trade-off questions, and patients were queried about specific concerns regarding medications. Vulnerability was defined according to the Vulnerable Elders Scale.
  
  
  RESULTS
  Thirty-six percent of patients were vulnerable. Vulnerable patients were older (77 vs 73) and had diabetes mellitus longer (13 vs 10 years; P<.05). Vulnerable patients reported lower utilities than nonvulnerable patients for most individual treatment states (e.g., intensive glucose control, mean 0.61 vs 0.72, P<.01), but within group variation was large for both groups (e.g., standard deviations >0.25). Although mean individual state utilities differed across groups, no significant differences were found in how vulnerable and nonvulnerable patients compared intensive and conventional treatment states (e.g., intensive vs conventional glucose control). In multivariable analyses, the association between vulnerability and individual treatment state utilities became nonsignificant except for the cholesterol pill.
  
  
  CONCLUSIONS
  Older patients' preferences for intensity of treatment for diabetes mellitus vary widely and are not closely associated with vulnerability. This observation underscores the importance of involving older patients in decisions about treatment for diabetes mellitus, irrespective of clinical status.
authors.affiliation: The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Sydney E S
authors.initials: SE
authors.lastname: Brown
authors.forename: David O
authors.initials: DO
authors.lastname: Meltzer
authors.forename: Marshall H
authors.initials: MH
authors.lastname: Chin
authors.forename: Elbert S
authors.initials: ES
authors.lastname: Huang
mesh_terms: D000368:Aged; D002641:Chicago; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000145:classification / Q000523:psychology* / Q000628:therapy; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D017060:Patient Satisfaction; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires