title: [The results of conservative therapy and the analysis of survival rate in drug addicted patients with infectious endocarditis].
abstract: 110 drug addicted patients with infectious endocarditis (IE), 67 males and 43 females with average age 24 +/- 3.2 years were examined. Positive results of conservative therapy were in 69.2% patients with isolated lesion of tricuspid valve. Hospital lethality in the group of patients was 35.5% (39 cases). The analysis of survival rate of IE patients with the use of Cox's regression model made possible to establish that main predictors of lethal outcome in the group of patients were dimensions of microbe vegetations on tricuspid valve more than 2 cm, development of acute left ventricle failure, DIC-syndrome, and high degree tricuspid valve failure. Presence of HIV in early stage and C hepatitis without clinical laboratory activity did not have significant influence on IE outcome in this group of patients.
authors.forename: V I
authors.initials: VI
authors.lastname: Ulanova
authors.forename: V I
authors.initials: VI
authors.lastname: Mazurov
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality*; D017707:Erythrocyte Transfusion / Q000379:methods*; D005260:Female; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D008297:Male; D016016:Proportional Hazards Models; D012426:Russia / Q000453:epidemiology; D019966:Substance-Related Disorders / Q000150:complications* / Q000401:mortality; D016019:Survival Analysis; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents