Molecular diagnosis of a bilateral panuveitis due to Borrelia burgdorferi sensu lato by cerebral spinal fluid analysis.
The present paper describes a case of bilateral panuveitis due to Borrelia burgdorferi sensu lato diagnosed by a PCR approach using cerebral spinal fluid. Since the culture of B. burgdorferi takes a long time to grow and the accuracy of serological tests is doubtful in patients, the PCR method of amplifying a B. burgdorferi flagellin could be suitable to make a positive diagnosis in a case of atypical clinical history of Lyme disease.
Wallet
Frédéric
F
Pole de Microbiologie, Laboratoire de Bacteriologie-Hygiene, Lille Cedex, France. fwallet@chru-lille.fr
Labalette
Pierre
P
Herwegh
Stéphanie
S
Loiez
Caroline
C
Margaron
Fabrice
F
Courcol
René  J
R
D015748:Borrelia burgdorferi Group / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D005260:Female; D005408:Flagellin / Q000235:genetics; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods*; D014605:Uveitis / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology
D005408:Flagellin