Acute pseudogout after pamidronate infusion.
A 72-year-old man, treated with a 60-mg intravenous infusion of pamidronate for shoulder hand syndrome, developed after few hours an acute pseudogout arthritis of his right knee. Diagnosis was confirmed by synovial fluid analysis and was associated with hypocalcemia. Only a few cases are reported in the literature. The mechanism of this potential side effect remains speculative.
Wendling
Daniel
D
Department of Rheumatology, University Teaching Hospital Minjoz, EA 3186, University of Franche-Comté, Boulevard Fleming, Besançon, France. dwendling@chu-besancon.fr
Tisserand
Guillaume
G
Griffond
Vincent
V
Saccomani
Clarisse
C
Toussirot
Eric
E
D000208:Acute Disease; D000368:Aged; D002805:Chondrocalcinosis / Q000139:chemically induced*; D004164:Diphosphonates / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D000077268:Pamidronate; D012019:Reflex Sympathetic Dystrophy / Q000188:drug therapy
D004164:Diphosphonates; D000077268:Pamidronate