Chelating tendencies of bioactive aminophosphonates.
The metal-binding abilities of a wide variety of bioactive aminophosphonates, from the simple aminoethanephosphonic acids to the rather large macrocyclic polyaza derivatives, are discussed with special emphasis on a comparison of the analogous carboxylic acid and phosphonic acid systems. Examples are given of the biological importance of metal ion - aminophosphonate interactions in living systems, and also of their actual and potential applicability in medicine.
Kiss
T
T
Department of Inorganic and Analytical Chemistry Kossuth Lajos University P.O. Box 21 Debrecen H -4010 Hungary.
Lázár
I
I
Kafarski
P
P