title: [Chemotherapy activity and pharmacokinetics of the fluoroquinolones generics Ofloxacin-PhPO and Pefloxacin-genova].
abstract: Therapeutic activity, pharmacokinetic and bioavailability on animals (inbred white mouse, rabbits) were evaluated for Ofloxacin-PhPO and Pefloxacin-genova in comparison with innovator products--Tarivid and Abaktal. The results of the experiments demonstrate that investigated generics by their therapeutic efficacy in animals and by bioavailability are similar to original products.
authors.forename: S N
authors.initials: SN
authors.lastname: Ptitsina
authors.forename: V I
authors.initials: VI
authors.lastname: Bobrov
authors.forename: M M
authors.initials: MM
authors.lastname: Borisov
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics*; D016568:Drugs, Generic / Q000493:pharmacokinetics; D008297:Male; D051379:Mice; D015242:Ofloxacin / Q000493:pharmacokinetics*; D015366:Pefloxacin / Q000493:pharmacokinetics*; D011817:Rabbits
chemical_list: D000900:Anti-Bacterial Agents; D016568:Drugs, Generic; D015366:Pefloxacin; D015242:Ofloxacin