Difference in physiogenomics between male and female infertility.
Infertility is an important condition in reproductive medicine. According to this work, there is only one identified physiogenomic relationship on chromosome 5 (CAMK4) for male but there are four identified physiogenomic relationships on chromosome 12 (CD9), chromosome 19 (BSG), chromosome 2 (ADCY3) and chromosome 4 (AFP). Although it has been determined for a long time, there is no clear cut genetic difference between male and female infertility. Systemic approach on the pathophysiology and genomics might provide useful information to better understand the pathogenesis of infertility. In this work, physiogenomics analysis for infertility in male and female was performed.
Wiwanitkit
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Wiwanitkit House, Bangkhae, Bangkok, Thailand; Hainan Medical College, Hainan, China. wviroj@yahoo.com
D000262:Adenylyl Cyclases / Q000235:genetics; D015703:Antigens, CD / Q000235:genetics; D051926:Basigin / Q000235:genetics; D054734:Calcium-Calmodulin-Dependent Protein Kinase Type 4 / Q000235:genetics; D019295:Computational Biology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000235:genetics* / Q000503:physiopathology*; D007248:Infertility, Male / Q000235:genetics* / Q000503:physiopathology*; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics; D060245:Tetraspanin 29; D000509:alpha-Fetoproteins / Q000235:genetics
C097353:AFP protein, human; D015703:Antigens, CD; C497886:BSG protein, human; C554869:CD9 protein, human; D008562:Membrane Glycoproteins; D060245:Tetraspanin 29; D000509:alpha-Fetoproteins; D051926:Basigin; C517683:CAMK4 protein, human; D054734:Calcium-Calmodulin-Dependent Protein Kinase Type 4; D000262:Adenylyl Cyclases