title: Circumstances of leakage related to low urethral closure pressure.
abstract: OBJECTIVE
  We determined whether urinary leakage in some circumstances is associated with intrinsic sphincter deficiency, defined by a low maximum urethral closure pressure of 30 cm H(2)O or less, in women presenting for urinary incontinence.
  
  
  METHODS
  We retrospective analyzed the records of 100 consecutive women who underwent complete urodynamic evaluations for complaints of urinary leakage.
  
  
  RESULTS
  Logistic regression adjusted for age showed that leakage while running or during physical exertion, leakage while walking and leakage with no obvious reason were associated with intrinsic sphincter deficiency, while leakage upon coughing or sneezing was not.
  
  
  CONCLUSIONS
  These results suggest that different mechanisms may govern incontinence during prolonged vs brief stress. Low maximum urethral closure pressure may be a sign of abnormal sphincter fatigability.
authors.affiliation: Service de Gynécologie et Obstétrique, Hôpital Rothschild Assistance Publique-Hôpitaux de Paris, Paris, France. fritel.xavier@orange.fr
authors.forename: Xavier
authors.initials: X
authors.lastname: Fritel
authors.forename: Arnaud
authors.initials: A
authors.lastname: Fauconnier
authors.forename: Alain
authors.initials: A
authors.lastname: Pigné
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D011312:Pressure; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014521:Urethra / Q000503:physiopathology*; D014549:Urinary Incontinence / Q000209:etiology*