title: Acute coronary syndrome in a patient with Marfan syndrome following emergent surgical repair of aortic dissection.
abstract: We report a case of acute coronary syndrome in a patient with suspect Marfan syndrome, 25 days after emergent modified Bentall-De Bono intervention for acute type I peripartum aortic dissection. She was admitted to our intensive care unit because of unstable angina, caused by critical blood flow reduction in a large portion of the myocardium, according to the severity of the symptoms and the electrocardiographic alterations. Coronary angiography showed a sub-occlusive stenosis of the left main coronary artery as a result of the dissection extension to the coronary ostium. Because of the high risk related to heart surgery, the patient was successfully treated by unprotected angioplasty and drug-eluting stent positioning. Short- and mid-term outcomes were favourable. Subsequent tests confirmed the diagnosis of Marfan syndrome. After 2 years of follow-up, the patient remains asymptomatic and in good health. To our knowledge, this is the first report of a successful percutaneous intervention of the left main coronary artery in a patient with Marfan syndrome who had already undergone ascending aortic root and valve replacement by the Bentall-De Bono procedure for acute dissection.
authors.affiliation: Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
authors.forename: Francesca Elisa
authors.initials: FE
authors.lastname: Bovolato
authors.forename: Giambattista
authors.initials: G
authors.lastname: Isabella
authors.forename: Debora
authors.initials: D
authors.lastname: Rampazzo
authors.forename: Cosimo
authors.initials: C
authors.lastname: Guglielmi
authors.forename: Gino
authors.initials: G
authors.lastname: Gerosa
authors.forename: Sabino
authors.initials: S
authors.lastname: Iliceto
authors.forename: Claudio
authors.initials: C
authors.lastname: Bilato
mesh_terms: D054058:Acute Coronary Syndrome; D000328:Adult; D000784:Aortic Dissection / Q000601:surgery*; D017130:Angioplasty; D001014:Aortic Aneurysm / Q000601:surgery*; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications*; D011183:Postoperative Complications; D015607:Stents