title: Clear lens phacoemulsification in the anterior lenticonus due to Alport Syndrome: two case reports.
abstract: BACKGROUND
  Alport Syndrome has a prevalence of 1 case per 5,000 people and 85% of patients have the X-linked form, where affected males develop renal failure and usually have high-tone sensorineural deafness by age 20. The main abnormality is deficient synthesis of type IV collagen, the main component of basement membranes. Common ocular abnormalities of this syndrome consist of dot-and-fleck retinopathy, posterior polymorphous corneal dystrophy, and anterior lenticonus, but other ocular defects such as cataracts, posterior lenticonus, and retinal detachments have also been reported.
  
  
  METHODS
  We report two cases of anterior lenticonus due to Alport Syndrome and describe clear lens phacoemulsification and foldable intraocular lens implantation as an effective and safe refractive procedure in the four eyes of these two patients.
  
  
  CONCLUSIONS
  All four eyes of the two patients were in good condition after surgery and achieved satisfactory optical and visual results and had no remarkable complications at six-months follow-up. Clear lens phacoemulsification with foldable intraocular lens implantation can be used as an efficient and safe procedure for vision disorders in these patients.
authors.affiliation: Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran. dr.aslanzadeh@gmail.com
authors.forename: Ghassem Amir
authors.initials: GA
authors.lastname: Aslanzadeh
authors.forename: Davoud
authors.initials: D
authors.lastname: Gharabaghi
authors.forename: Niloofar
authors.initials: N
authors.lastname: Naderi