Ti-mediated direct and highly stereoselective Mannich reactions between esters and oxime ethers.
The first general method of direct and highly stereoselective Ti-mediated Mannich reaction between three types of simpleesters and E and Z mixtures of oxime ethers (aliphatic and aromatic) is accomplished.
Funatomi
Takashi
T
Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo, 669-1337, Japan.
Nakazawa
Shogo
S
Matsumoto
Kunshi
K
Nagase
Ryohei
R
Tanabe
Yoo
Y