title: Benzyne click chemistry: synthesis of benzotriazoles from benzynes and azides.
abstract: A variety of substituted benzotriazoles have been prepared by the [3 + 2] cycloaddition of azides to benzynes. The reaction scope is quite general, affording a rapid and easy entry to substituted, functionalized benzotriazoles under mild conditions.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, IA 50010, USA.
authors.forename: Feng
authors.initials: F
authors.lastname: Shi
authors.forename: Jesse P
authors.initials: JP
authors.lastname: Waldo
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D001386:Azides / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis*
chemical_list: D001386:Azides; D001555:Benzene Derivatives; D014230:Triazoles; C524146:benzyne; C012771:benzotriazole