[Assessment of sFas concentration in serum of uveitis patients].
OBJECTIVE
To evaluate the concentration of sFas in serum of uveitis patients.


METHODS
Serum samples were collected from 13 patients with uveitis and 12 controls. All patients have underwent ophthalmic and laboratory examinations. The sFas levels were determined by immunoenzymatic assay ELISA.


RESULTS
We found statistically increased levels of sFas in serum of patients with uveitis compared with controls.


CONCLUSIONS
Our results suggest a systemic nature of uveitis with persistent activation of the immune system. Apoptosis may play regulatory role in ocular inflammation of patients with uveitis.
Mrugacz
Małgorzata
M
Kliniki Okulistyki Dzieciecej Akademii Medycznej w Białymstoku.
Bakunowicz-Lazarczyk
Alina
A
Sredzińska-Kita
Dorota
D
Zelazowska-Rutkowska
Beata
B
Wysocka
Jolanta
J
D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009887:Ophthalmoscopy; D014605:Uveitis / Q000097:blood* / Q000175:diagnosis*; D014792:Visual Acuity; D019014:fas Receptor / Q000097:blood*
D019014:fas Receptor