title: Four new chalcones from Erythrina abyssinica.
abstract: Four new chalcones 1 - 4, named abyssinones A - D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC (50) values of 13.3, 15.1, and 11.1 microM, respectively.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.
authors.forename: Long
authors.initials: L
authors.lastname: Cui
authors.forename: Phuong Thien
authors.initials: PT
authors.lastname: Thuong
authors.forename: Hyun Sun
authors.initials: HS
authors.lastname: Lee
authors.forename: Dieudonné
authors.initials: D
authors.lastname: Njamen
authors.forename: Joseph Tanyi
authors.initials: JT
authors.lastname: Mbafor
authors.forename: Z Tanee
authors.initials: ZT
authors.lastname: Fomum
authors.forename: Junwon
authors.initials: J
authors.lastname: Lee
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
authors.forename: Won Keun
authors.initials: WK
authors.lastname: Oh
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology*; D047188:Chalcones / Q000737:chemistry* / Q000494:pharmacology*; D004895:Erythrina / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D047188:Chalcones