Late pulmonary tomography assessment in premature infants with bronchopulmonary dysplasia submitted to patent ductus arteriosus management.
OBJECTIVE
To assess through high-resolution computed tomography the pulmonary parenchyma of children prematurely born with both very low birth weight and patent ductus arteriosus submitted to medical or surgical treatment that developed bronchopulmonary dysplasia.


METHODS
Between December 2006 and January 2007, 14 children prematurely born with a weight less than 1500 g with bronchopulmonary dysplasia (BPD) and patent ductus arteriosus (PDA) were submitted to high-resolution computed tomography (HRCT). All of them underwent surgical closure of the canal divided into two groups: A - medical (n=6) and B - surgical (n=8). The pool of patients comprised 9 baby boys and 5 girls who were 36.5+/-4.3 month-old. The HRCT were analyzed by two independent observers and quantified in each patient. The statistical analyses were assessed using the Mann-Whitney test, and p<0.05 was considered statistically significant.


RESULTS
Three patients presented normal tomographies, being two of A group and one of B. In A, the most frequent finding was multifocal ground-glass opacity. In B, multifocal ground-glass opacity, atelectasis, and low attenuation areas with relatively decreased number and caliber of vessels were prevalent (62.5%). There was a statistically significant difference between both groups, with B having higher averages in the intubation times, use of oxygen, and admission. However, as to the number of injuries found on HRCT there was no statistically significant difference (p=0.0787).


CONCLUSIONS
The lately use of HRCT have shown no significant difference between both medical and surgical treatment aiming at to occlude the PDA in pulmonary parenchyma injuries of premature with PDA that developed bronchopulmonary dysplasia.
Beani
Lilian
L
Medical School of São José do Rio Preto (FAMERP). lilianbeani@uol.com.br
Moscardini
Airton Camacho
AC
Souza
Antonio Soares
AS
Souza
Arthur Soares
AS
Yamamoto
Adriana Erica
AE
Croti
Ulisses Alexandre
UA
Braile
Domingo Marcolino
DM
D001997:Bronchopulmonary Dysplasia / Q000000981:diagnostic imaging* / Q000209:etiology; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D001261:Pulmonary Atelectasis / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed