Four new chalcones from Erythrina abyssinica.
Four new chalcones 1 - 4, named abyssinones A - D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC (50) values of 13.3, 15.1, and 11.1 microM, respectively.
Cui
Long
L
Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.
Thuong
Phuong Thien
PT
Lee
Hyun Sun
HS
Njamen
Dieudonné
D
Mbafor
Joseph Tanyi
JT
Fomum
Z Tanee
ZT
Lee
Junwon
J
Kim
Young Ho
YH
Oh
Won Keun
WK
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology*; D047188:Chalcones / Q000737:chemistry* / Q000494:pharmacology*; D004895:Erythrina / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems
D000972:Antineoplastic Agents, Phytogenic; D047188:Chalcones