[Edema related to treatment with olanzapine].
OBJECTIVE
In comparison to metabolic syndrome, edema seems to be a rare occurrence in antipsychotic treatment.


METHODS
In this paper, we report on two subjects with psychotic disorders who were found to have peripheral edema during olanzapine therapy.


CONCLUSIONS
The theoretical background and the relevance of this observation are examined. Furthermore, edema as a side effect of antipsychotic treatment is reviewed. In particular, the importance of olanzapine, a commonly used neuroleptic drug, as a possible causative substance is evaluated.
Wustmann
Tobias
T
Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Martin-Luther-Universität Halle-Wittenberg. tobias.wustmann@medizin.uni-halle.de
Fiedler
Thiemo
T
Gutmann
Philipp
P
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D003987:Dibenzothiazepines / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004487:Edema / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D000077152:Olanzapine; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000069348:Quetiapine Fumarate; D018967:Risperidone / Q000627:therapeutic use
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D001569:Benzodiazepines; D000069348:Quetiapine Fumarate; D018967:Risperidone; D000077152:Olanzapine