title: Pseudoaneurysm of the peroneal artery: presentation of Ehlers-Danlos syndrome type IV.
abstract: BACKGROUND
  Pseudoaneurysms in deep or unusual sites raise the possibility of an underlying vessel wall disorder.
  
  
  METHODS
  A 28-year-old woman presented with pain and swelling of her calf, with no history of trauma. Angiography diagnosed a peroneal artery pseudoaneurysm, which we embolised successfully. Subsequent genetic analysis revealed the COL3A1 mutation, confirming Ehlers-Danlos syndrome type IV.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of a peroneal artery pseudoaneurysm associated with underlying collagen vascular disease.
authors.affiliation: St Mary's Hospital, South Wharf Road, Paddington, London W2 1NY, United Kingdom. kate.mandeville@imperial.ac.uk
authors.forename: K
authors.initials: K
authors.lastname: Mandeville
authors.forename: C
authors.initials: C
authors.lastname: Bicknell
authors.forename: T
authors.initials: T
authors.lastname: Tran
authors.forename: K
authors.initials: K
authors.lastname: MacDermot
authors.forename: S
authors.initials: S
authors.lastname: Renton
mesh_terms: D000328:Adult; D017541:Aneurysm, False / Q000209:etiology* / Q000628:therapy; D024061:Collagen Type III / Q000235:genetics; D004535:Ehlers-Danlos Syndrome / Q000150:complications* / Q000235:genetics; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans
chemical_list: C439971:COL3A1 protein, human; D024061:Collagen Type III