title: New polyunsaturated fatty acid amides isolated from the seeds of Zanthoxylum piperitum.
abstract: Five linear fatty acid amides (1-5) of the sandshool class, including two new compounds, were isolated from Zanthoxylum piperitum seeds. Based on combined spectral analyses, the structures of new compounds 4 and 5 were determined to be 2',3'-dihydroxy-alpha-sanshool and 2',3'-dihydroxy-beta-sanshool, respectively. These compounds exhibited weak cytotoxicity in the A-549 (human lung cancer) cell line.
authors.affiliation: College of Pharmacy, Seoul National University, Seoul, 110-460, Korea.
authors.forename: Kyoung Hwa
authors.initials: KH
authors.lastname: Jang
authors.forename: Yong Ha
authors.initials: YH
authors.lastname: Chang
authors.forename: Dae-Duk
authors.initials: DD
authors.lastname: Kim
authors.forename: Ki-Bong
authors.initials: KB
authors.lastname: Oh
authors.forename: Uhtaek
authors.initials: U
authors.lastname: Oh
authors.forename: Jongheon
authors.initials: J
authors.lastname: Shin
mesh_terms: D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: D000577:Amides; D003603:Cytotoxins; D005231:Fatty Acids, Unsaturated; C100574:sanshool