Internal kinematics of the tongue following volume reduction.
This study was undertaken to determine the functional consequences following tongue volume reduction on tongue internal kinematics during mastication and neuromuscular stimulation in a pig model. Six ultrasonic-crystals were implanted into the tongue body in a wedge-shaped configuration which allows recording distance changes in the bilateral length (LENG) and posterior thickness (THICK), as well as anterior (AW), posterior dorsal (PDW), and ventral (PVW) widths in 12 Yucatan-minipigs. Six animals received a uniform mid-sagittal tongue volume reduction surgery (reduction), and the other six had identical incisions without tissue removal (sham). The initial-distances among each crystal-pairs were recorded before, and immediately after surgery to calculate the dimensional losses. Referring to the initial-distance there were 3-66% and 1-4% tongue dimensional losses by the reduction and sham surgeries, respectively. The largest deformation in sham animals during mastication was in AW, significantly larger than LENG, PDW, PVW, and THICK (P < 0.01-0.001). In reduction animals, however, these deformational changes significantly diminished and enhanced in the anterior and posterior tongue, respectively (P < 0.05-0.001). In both groups, neuromuscular stimulation produced deformational ranges that were 2-4 times smaller than those occurred during chewing. Furthermore, reduction animals showed significantly decreased ranges of deformation in PVW, LENG, and THICK (P < 0.05-0.01). These results indicate that tongue volume reduction alters the tongue internal kinematics, and the dimensional losses in the anterior tongue caused by volume reduction can be compensated by increased deformations in the posterior tongue during mastication. This compensatory effect, however, diminishes during stimulation of the hypoglossal nerve and individual tongue muscles.
Shcherbatyy
Volodymyr
V
Department of Orthodontics, University of Washington, Seattle, Washington 98195-3446, USA.
Perkins
Jonathan A
JA
Liu
Zi-Jun
ZJ
D000818:Animals; D001696:Biomechanical Phenomena; D004558:Electric Stimulation; D005260:Female; D007002:Hypoglossal Nerve / Q000502:physiology; D008297:Male; D008409:Mastication / Q000502:physiology; D023421:Models, Animal; D013552:Swine; D013556:Swine, Miniature; D014059:Tongue / Q000033:anatomy & histology / Q000294:innervation / Q000502:physiology* / Q000601:surgery