title: Molecular virology of feline calicivirus.
abstract: Caliciviridae are small, nonenveloped, positive-stranded RNA viruses. Much of our understanding of the molecular biology of the caliciviruses has come from the study of the naturally occurring animal caliciviruses. In particular, many studies have focused on the molecular virology of feline calicivirus (FCV), which reflects its importance as a natural pathogen of cats. FCVs demonstrate a remarkable capacity for high genetic, antigenic, and clinical diversity; "outbreak" vaccine resistant strains occur frequently. This article updates the reader on the current status of clinical behavior and pathogenesis of FCV.
authors.affiliation: Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, 4206 VM3A, Davis, CA 95616-5270, USA. papesavento@ucdavis.edu
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Pesavento
authors.forename: Kyeong-Ok
authors.initials: KO
authors.lastname: Chang
authors.forename: John S L
authors.initials: JS
authors.lastname: Parker
mesh_terms: D000818:Animals; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D017927:Calicivirus, Feline / Q000235:genetics* / Q000472:pathogenicity; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D004196:Disease Outbreaks / Q000662:veterinary; D005260:Female; D014644:Genetic Variation; D008297:Male; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D014774:Virulence
chemical_list: D012367:RNA, Viral