title: Direct synthesis of 1,3-diketones by Rh-catalyzed reductive alpha-acylation of enones.
abstract: 1,3-Diketones were synthesized from alpha,beta-unsaturated ketones by treatment with acid chlorides and Et(2)Zn in the presence of RhCl(PPh(3))3. This is a very simple and extremely chemoselective reaction to give the adduct at the alpha-position of alpha,beta-unsaturated ketones.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Sato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamazoe
authors.forename: Rie
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Shizuka
authors.initials: S
authors.lastname: Ohata
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tarui
authors.forename: Masaaki
authors.initials: M
authors.lastname: Omote
authors.forename: Itsumaro
authors.initials: I
authors.lastname: Kumadaki
authors.forename: Akira
authors.initials: A
authors.lastname: Ando
mesh_terms: D000215:Acylation; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007659:Ketones; D012238:Rhodium