The fetal response to chronic placental insufficiency.
Fetal growth restriction is most commonly caused by failure of the placenta to meet the increasing demands for oxygen and substrate of the developing fetus, resulting in common fetal compensatory responses. Understanding these responses is helpful in developing a management strategy that will optimize pregnancy outcome.
Neerhof
Mark G
MG
Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Evanston Northwestern Healthcare, Evanston, IL 60201, USA. mneerhof@enh.org
Thaete
Larry G
LG
D000222:Adaptation, Physiological; D001783:Blood Flow Velocity; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D005311:Fetal Hypoxia / Q000378:metabolism / Q000503:physiopathology; D005333:Fetus / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D010920:Placenta / Q000098:blood supply*; D010927:Placental Insufficiency / Q000503:physiopathology*; D011247:Pregnancy