The explosive-degrading cytochrome P450 system is highly conserved among strains of Rhodococcus spp.
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a widely used explosive and a serious environmental pollutant. Nineteen strains of Rhodococcus spp. capable of utilizing RDX as the sole nitrogen source have been isolated. The cytochrome P450 system XplA-XplB, which is responsible for RDX breakdown, is present in 18 of these strains.
Seth-Smith
Helena M B
HM
Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1TJ, United Kingdom.
Edwards
James
J
Rosser
Susan J
SJ
Rathbone
Deborah A
DA
Bruce
Neil C
NC
D015373:Bacterial Typing Techniques; D001673:Biodegradation, Environmental; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism; D004269:DNA, Bacterial / Q000302:isolation & purification; D053834:Explosive Agents / Q000378:metabolism*; D009584:Nitrogen / Q000378:metabolism; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000302:isolation & purification; D012240:Rhodococcus / Q000145:classification / Q000201:enzymology* / Q000235:genetics; D017422:Sequence Analysis, DNA; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000378:metabolism*; D014227:Triazines / Q000378:metabolism*
D004269:DNA, Bacterial; D053834:Explosive Agents; D012336:RNA, Ribosomal, 16S; D012989:Soil Pollutants; D014227:Triazines; D003577:Cytochrome P-450 Enzyme System; D009584:Nitrogen; C009160:cyclonite