title: Associations of sleep-disordered breathing with excessive daytime sleepiness and blood pressure in Japanese women.
abstract: Sleep-disordered breathing (SDB) is a recognized risk factor for excessive daytime sleepiness (EDS) and hypertension, but evidence of this association in Asian women is limited. We conducted a cross-sectional study of 3,568 women aged 30-69 years living in three Japanese communities. The 3% oxygen desaturation index (ODI) was selected as the indicator of SDB, and blood oxygen fall was estimated by overnight pulse oximetry. The prevalence of SDB was 20.2% for 3% ODI>or=5, 6.4% for 3% ODI>or=10, and 2.8% for 3% ODI>or=15 among Japanese women aged 30-69 years. The 3% ODI was positively associated with the prevalence of self-reported EDS and mean values of systolic and diastolic blood pressure levels. The multivariate odds ratios for 3% ODI of 5-9, 10-14, and >or=15 in reference to 3% ODI<5 were 1.9 (1.2-3.0), 2.2 (1.0-4.6), and 1.8 (0.7-4.4) (p for trend=0.01), respectively, for EDS and 1.1 (0.9-1.4), 1.2 (0.8-1.8), and 2.2 (1.4-3.4) (p for trend<0.001), respectively, for hypertension. The severity of SDB was significantly associated with EDS and hypertension among Japanese women.
authors.affiliation: Department of Epidemiology and Community Medicine, Medical College of Nankai University, Tianjin, PR China.
authors.forename: Renzhe
authors.initials: R
authors.lastname: Cui
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tanigawa
authors.forename: Susumu
authors.initials: S
authors.lastname: Sakurai
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Yamagishi
authors.forename: Hironori
authors.initials: H
authors.lastname: Imano
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ohira
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kitamura
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sato
authors.forename: Takashi
authors.initials: T
authors.lastname: Shimamoto
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iso
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000503:physiopathology; D003430:Cross-Sectional Studies; D006970:Disorders of Excessive Somnolence / Q000208:ethnology / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology; D007564:Japan / Q000453:epidemiology; D008875:Middle Aged; D015999:Multivariate Analysis; D010100:Oxygen / Q000097:blood; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology
chemical_list: D010100:Oxygen