title: 2008 update of international guidelines for the management of severe sepsis and septic shock: should we change our current clinical practice?
authors.forename: Roman Z
authors.initials: RZ
authors.lastname: Jaeschke
authors.forename: Jan L
authors.initials: JL
authors.lastname: Brozek
authors.forename: R Phillip
authors.initials: RP
authors.lastname: Dellinger
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002985:Clinical Protocols; D003422:Critical Care / Q000592:standards*; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006801:Humans; D007391:International Cooperation; D017410:Practice Guidelines as Topic; D018805:Sepsis / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D012772:Shock, Septic / Q000175:diagnosis / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D002317:Cardiovascular Agents