Particle image velocimetry measurements of three proximal anastomosis models under a pulsatile flow condition.
This study was designed to examine the effects of the anastomotic angle on the flow and haemodynamic parameter distribution patterns of the proximal anastomoses, with emphasis on identifying site-specific haemodynamic features that could reasonably be expected to trigger the initiation and further development of anastomotic intimal hyperplasia. Particle image velocimetry measurements were carried out with three simplified glass proximal models under a physiological flow condition. The results revealed that the disturbed flow and the induced shear stress patterns including low recirculation flow, stagnation point, high wall shear stress, high temporal wall shear stress gradient, low time-averaged wall shear stress (TAWSS), and high oscillating shear index (OSI) occurred around the anastomotic joints and the flow field at proximal anastomosis was strongly affected by the anastomotic angle. Among the three models investigated, the 45 degrees backward anastomosis is found to have a smaller low-recirculation-flow region along the graft inner wall, non-stationary stagnation, and separation points, a higher TAWSS and smaller high-OSI low-TAWSS and low-OSI high-TAWSS regions.
Chua
L P
LP
School of Mechanical and Aerospace Engineering, Thermal and Fluids Engineering Division, Nanyang Technological University, Singapore. mlpchua@ntu.edu.sg
Ji
W-F
WF
Yu
C M
CM
Zhou
T-M
TM
Tan
Y S
YS
D000714:Anastomosis, Surgical / Q000009:adverse effects; D001783:Blood Flow Velocity; D003251:Constriction, Pathologic / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D006965:Hyperplasia / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D008955:Models, Cardiovascular; D008961:Models, Structural; D011673:Pulsatile Flow; D012212:Rheology / Q000295:instrumentation*; D033081:Shear Strength; D013314:Stress, Mechanical; D017539:Tunica Intima / Q000503:physiopathology*