title: [Effect of continuous blood purification for management of multiple organ failure with acute renal failure].
abstract: OBJECTIVE
  To evaluate the effect of continuous blood purification (CBP) for treatment of multiple organ failure (MOF) with acute renal failure (ARF).
  
  
  METHODS
  Forty-seven patients with MOF underwent CBP for an average of 3.1-/+0.5 days averagely. Continuous veno-venous hemofiltration was performed at daytime, and the substitute fluids were infused with pre-dilution at the rate of 2000-4000 ml/h. The general conditions, clinical symptoms, and serum biochemical indexes of the patients were observed and MODS score was calculated.
  
  
  RESULTS
  After CBP, the MODS score of the patients decreased significantly from 9.1-/+3.5 to 5.4-/+2.7 (P<0.01) and serum creatinine decreased from 451.3-/+134.5 to 223.7-/+100.2 micromol/L (P<0.05). Twenty-nine patients survived with the survival rate of 61.7%.
  
  
  CONCLUSIONS
  CBP is effective for treatment of MOF and may help reduce the mortality rate of MOF complicated by ARF.
authors.affiliation: Department of Nephrology, Shenzhen Sixth People's Hospital, Shenzhen 518052, China. fanghc-0397@sohu.com
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
authors.forename: Jiu-hong
authors.initials: JH
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Jiang
authors.forename: Sheng-lang
authors.initials: SL
authors.lastname: Zhu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000628:therapy*; D010195:Pancreatitis / Q000150:complications; D051437:Renal Insufficiency / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000150:complications; D055815:Young Adult