Can we cause regression of coronary atherosclerosis?
With the advent of effective antiatherosclerotic therapies, especially lipid lowering agents, cardiovascular morbidity and mortality rates associated with coronary atherosclerosis can be reduced. A growing body of evidence suggests such therapies can retard the progression of coronary atherosclerosis and with aggressive treatment regimens can cause regression. Antiatherosclerotic, and especially lipid lowering therapies, have the potential to become an alternative to invasive interventions. This report examines clinical studies that have addressed the regression of human coronary atherosclerosis by medical therapy.
Alsafwah
Shadwan
S
Division of Cardiovascular Diseases, University of Tennessee Health Science Center and Veterans Administration Medical Center, Memphis, Tennessee, USA.
Ramanathan
Kodangudi B
KB
D002121:Calcium Channel Blockers / Q000627:therapeutic use; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D002986:Clinical Trials as Topic; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy*; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D006801:Humans; D002785:Sterol O-Acyltransferase / Q000037:antagonists & inhibitors; D014463:Ultrasonography
D002121:Calcium Channel Blockers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D002785:Sterol O-Acyltransferase