Paraganglioma: a potentially challenging tumor.
Paragangliomas are usually low-grade neoplasms with a benign natural history. While the treatment of paraganglioma has historically been controversial, surgery and radiotherapy have become standardized as therapies of choice for primary therapy. More recently, stereotactic radiosurgery has been used effectively against this rare tumor. The development of metastatic disease in patients with paraganglioma is an unusual and challenging event. This case report and review describes the specific features of this disease and the multiple therapeutic options.
Trombetta
Mark
M
Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA. mtrombet@wpahs.org
Silverman
Jan
J
Colonias
Athanasios
A
Lee
Vincent
V
Mohanty
Alok
A
Parda
David
D
D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010235:Paraganglioma / Q000175:diagnosis* / Q000628:therapy*