title: Familial cholesteatoma in East Anglia, UK.
abstract: OBJECTIVE
  To report a cluster of families affected by cholesteatoma in the East Anglia region of the UK.
  
  
  METHODS
  Otology service for the population of Norfolk and North Suffolk, East Anglia, UK.
  
  
  METHODS
  Prospective and systematic collection of family history data for patients presenting with cholesteatoma over 10 years.
  
  
  RESULTS
  Several families were identified with affected individuals over several generations.
  
  
  CONCLUSIONS
  There is likely to be a genetic propensity for cholesteatoma in some individuals.
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, James Paget and Norfolk and Norwich University Hospitals, UK. prinsley@mac.com
authors.forename: P
authors.initials: P
authors.lastname: Prinsley
mesh_terms: D000328:Adult; D002648:Child; D018424:Cholesteatoma, Middle Ear / Q000453:epidemiology / Q000235:genetics*; D016000:Cluster Analysis; D004739:England / Q000453:epidemiology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D010375:Pedigree; D011446:Prospective Studies