Primary cutaneous follicle center lymphoma associated with alopecia areata.
We report a patient who presented simultaneously with primary cutaneous follicle center lymphoma (PCFCL) of the face and scalp and alopecia areata of the scalp and beard bearing a clonal T-cell receptor gene rearrangement. To our knowledge, alopecia areata has not been previously reported in association with PCFCL. Both lesions regressed with topical imiquimod and systemic steroids, which suggests an inter-relationship in this case between the clonal B-cell and T-cell populations in driving outgrowth of these lesions.
Richmond
Heather M
HM
Cedars Sinai Medical Center, Los Angeles, CA, USA. heather.richmond@gmail.com
Lozano
Annabelle
A
Jones
Dan
D
Duvic
Madelein
M
D000328:Adult; D000506:Alopecia Areata / Q000150:complications* / Q000473:pathology*; D019382:Human Growth Hormone / Q000235:genetics; D006801:Humans; D008224:Lymphoma, Follicular / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D016133:Polymerase Chain Reaction; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D019382:Human Growth Hormone