Rebound abdominal pain: noncephalic pain in abdominal migraine is exacerbated by medication overuse.
Abdominal migraine usually has its onset during childhood or adolescence and resolves in adulthood, often being replaced by typical migraine headaches. Rarely, migraine headache and recurrent abdominal pain coexist in some patients during adulthood. We report a patient who developed abdominal migraine without headaches beginning for the first time at the age of 22 years. The abdominal symptoms increased in frequency coincident with medication overuse and resolved after the overuse was treated. Analgesic overuse may cause a worsening of noncephalic pain in patients with extra-cephalic variants of migraine.
Newman
Lawrence C
LC
Headache Institute, Roosevelt Hospital Center, New York, NY, USA.
Newman
Eric B
EB
D015746:Abdominal Pain / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D000328:Adult; D000367:Age Factors; D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005283:Fentanyl / Q000009:adverse effects* / Q000627:therapeutic use; D051271:Headache Disorders, Secondary / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D010098:Oxycodone / Q000009:adverse effects* / Q000627:therapeutic use; D012008:Recurrence; D014700:Verapamil / Q000627:therapeutic use
D000701:Analgesics, Opioid; D002121:Calcium Channel Blockers; D010098:Oxycodone; D014700:Verapamil; D005283:Fentanyl