title: Outcome of an adult granulosa cell tumour in an adolescent initially managed by laparoscopy.
abstract: Adult granulosa cell tumour is rarely encountered in adolescents. Tumours in their early stages have a favourable prognosis whereas those in advanced stages have a poor outcome. Documented series of tumours at advanced stages are very rare and follow-up is difficult because of the frequently prolonged intervals before progression of the tumour. That may explain why it is very difficult to define a consensual management strategy with or without adjuvant therapy such as chemotherapy or radiation therapy. We describe a case of adult granulosa cell tumour in a 14-year-old girl who initially underwent laparoscopy for an "unsuspicious" cyst. Management was then modified according to oncological guidelines because of the histological nature of this cyst.
authors.affiliation: Pediatric Surgery Department, University Hospital of Strasbourg, Strasbourg, France. isabelle.talon2@chru-strasbourg.fr
authors.forename: I
authors.initials: I
authors.lastname: Lacreuse
authors.forename: F
authors.initials: F
authors.lastname: Becmeur
authors.forename: L
authors.initials: L
authors.lastname: Marcelin
authors.forename: P
authors.initials: P
authors.lastname: Lutz
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D005260:Female; D006106:Granulosa Cell Tumor / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome