title: Novel intra-arterial strategies in the treatment of acute ischaemic stroke.
abstract: Acute ischaemic stroke is among the leading causes of death and disability in developed societies. I.v. and intra-arterial thrombolysis, and mechanical thrombectomy carried out within the appropriate time window can result in superior clinical outcomes compared with traditional therapy consisting of anticoagulation and/or aspirin. In cases where thrombolysis and/or thrombectomy have not been proven effective or have failed to result in rapid clinical and/or angiographic improvement, novel intra-arterial strategies may be applied by experienced interventional neuroradiologists to achieve recanalization of recalcitrant vessel occlusions with good clinical outcomes.
authors.affiliation: Interventional Neuroradiology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA. perry.ng@hsc.utah.edu
authors.forename: P P
authors.initials: PP
authors.lastname: Ng
authors.forename: E A
authors.initials: EA
authors.lastname: Stevens
authors.forename: E J
authors.initials: EJ
authors.lastname: Skalabrin
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications* / Q000601:surgery*; D002548:Cerebral Revascularization / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control*; D016896:Treatment Outcome