title: TiO2 nanoparticles as a soft X-ray molecular probe.
abstract: This communication reports the development of a TiO2-streptavidin nanoconjugate as a new biological label for X-ray bio-imaging applications; this new probe, used in conjunction with the nanogold probe, will make it possible to obtain quantitative, high-resolution information about the location of proteins using X-ray microscopy.
authors.affiliation: Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
authors.forename: Jared M
authors.initials: JM
authors.lastname: Ashcroft
authors.forename: Weiwei
authors.initials: W
authors.lastname: Gu
authors.forename: Tierui
authors.initials: T
authors.lastname: Zhang
authors.forename: Steven M
authors.initials: SM
authors.lastname: Hughes
authors.forename: Keith B
authors.initials: KB
authors.lastname: Hartman
authors.forename: Cristina
authors.initials: C
authors.lastname: Hofmann
authors.forename: Antonios G
authors.initials: AG
authors.lastname: Kanaras
authors.forename: David A
authors.initials: DA
authors.lastname: Kilcoyne
authors.forename: Mark
authors.initials: M
authors.lastname: Le Gros
authors.forename: Yadong
authors.initials: Y
authors.lastname: Yin
authors.forename: A Paul
authors.initials: AP
authors.lastname: Alivisatos
authors.forename: Carolyn A
authors.initials: CA
authors.lastname: Larabell
mesh_terms: D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D017348:Microscopy, Electron, Scanning Transmission / Q000379:methods; D015335:Molecular Probes / Q000737:chemistry*; D015394:Molecular Structure; D010316:Particle Size; D019809:Streptavidin / Q000737:chemistry; D014025:Titanium / Q000737:chemistry*; D014965:X-Rays
chemical_list: D015335:Molecular Probes; C009495:titanium dioxide; D006046:Gold; D019809:Streptavidin; D014025:Titanium