Aquaporin 1 expression in tissues of canines possessing inherited high K+ erythrocytes.
We investigated the expression of aquaporin 1 (AQP1) in tissues from canines with an inherited anomaly that causes their erythrocytes to have high K(+). Northern blot analysis revealed abundant AQP1 expression in lung and kidney, though little expression was found in spleen. Using anti-C-terminus for dog AQP1, abundant expression was shown in kidney, trachea, and eye, but little expression was shown in pancreas and cerebrum, indicating that AQP1 expression in canine tissues is similar to that noted in other mammals.
Ochiai
Hideharu
H
Research Institute of Biosciences, Azabu University, Kanagawa 229-8501, Japan. ochiaih@azabu-u.ac.jp
Hishiyama
Nobuya
N
Hisamatsu
Shin
S
Kanemaki
Nobuyuki
N
D000818:Animals; D051398:Aquaporin 1 / Q000378:metabolism*; D015152:Blotting, Northern; D004285:Dogs; D004912:Erythrocytes / Q000737:chemistry*; D015151:Immunoblotting; D011188:Potassium / Q000032:analysis*; D014781:Viscera / Q000378:metabolism
D051398:Aquaporin 1; D011188:Potassium