title: A Preparation of enantiomerically enriched axially chiral beta-diketimines: synthesis of (-)- and (+)-IAN amine.
abstract: The preparation of an enantiomerically enriched beta-diketimine composed of isoquinoline and 2-aminonaphthalene (IAN amine) is described, thereby offering new opportunities in the synthesis of nonracemic beta-diketimine- and pyridine-based chiral catalysts.
authors.affiliation: Department of Chemistry & Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235-1822, USA.
authors.forename: Sarah B
authors.initials: SB
authors.lastname: Luesse
authors.forename: Carla M
authors.initials: CM
authors.lastname: Counceller
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Wilt
authors.forename: Brittany R
authors.initials: BR
authors.lastname: Perkins
authors.forename: Jeffrey N
authors.initials: JN
authors.lastname: Johnston
mesh_terms: D015081:2-Naphthylamine / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007546:Isoquinolines / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000588:Amines; D007546:Isoquinolines; D009281:Naphthalenes; D015081:2-Naphthylamine