[Uveitis intermedia in Whipple's disease].
We report a case of a 45-year-old man who complained of progressive vision loss in his right eye. Visual acuity was 20/300 in the right eye and 20/25 in the left eye. Bilateral uveitis intermedia R>L was diagnosed and treated with systemic and local steroids. An internal checkup was also done, and duodenal biopsy identified Whipple's disease. Despite specific antibiotic therapy, the patient's follow-up examination showed increased inflammatory activity R>L and bilateral cataracta complicata. Cataract surgery and pars plana vitrectomy with removal of epiretinal membranes were done. Histologic analysis of the vitreous and epiretinal membranes showed periodic acid-Schiff-positive macrophages, pathognomonic for Whipple's disease. Whipple's disease is a rare but severe disease with multiple manifestations and should be considered a differential diagnosis in uveitis.
Vehr
S
S
Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Leipzig, Liebigstrasse 10-14, 04103, Leipzig, Deutschland. stefanie.vehr@web.de
Nestler
A
A
Schütz
A
A
Halm
U
U
Meier
P
P
D006801:Humans; D008297:Male; D008875:Middle Aged; D015867:Uveitis, Intermediate / Q000150:complications* / Q000628:therapy*; D014786:Vision Disorders / Q000209:etiology* / Q000517:prevention & control*; D008061:Whipple Disease / Q000150:complications* / Q000628:therapy*