title: Male breast cancer 15 years after allogeneic hematopoietic cell transplantation including total body irradiation for recurrent acute lymphoblastic leukemia.
abstract: BACKGROUND
  Over the years, the prognosis following treatment of a primary cancer has significantly improved. However, the growing population of these cancer survivors has led to the realization of multiple longterm complications secondary to their treatment. One of the most devastating long-term complications is the development of a second malignancy.
  
  
  METHODS
  We report here the case of a 34-year-old man who developed stage IIB node-positive breast cancer almost 15 years following total body irradiation and allogeneic hematopoietic cell transplantation for acute lymphoblastic leukemia. To our knowledge, this is only the second report of a male breast cancer following allogeneic bone marrow transplantation (BMT).
  
  
  CONCLUSIONS
  Survivors of primary cancer need lifelong monitoring for complications from their initial therapy.
authors.affiliation: City of Hope Comprehensive Cancer Center, Duarte, CA 91010-3000, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lowe
authors.forename: Thehang
authors.initials: T
authors.lastname: Luu
authors.forename: Jeannie
authors.initials: J
authors.lastname: Shen
authors.forename: Smita
authors.initials: S
authors.lastname: Bhatia
authors.forename: Stephen
authors.initials: S
authors.lastname: Shibata
authors.forename: Anthony
authors.initials: A
authors.lastname: Stein
authors.forename: George
authors.initials: G
authors.lastname: Somlo
mesh_terms: D000328:Adult; D018567:Breast Neoplasms, Male / Q000175:diagnosis / Q000209:etiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000628:therapy*; D014916:Whole-Body Irradiation / Q000009:adverse effects*