title: Endosulfan and other organochlorine pesticide residues in maternal and cord blood in North Indian population.
abstract: Humans are exposed to various environmental chemicals such as organochlorine pesticide residues, heavy metals, polychlorinatedbiphenyls (PCBs) etc. There is paucity of data regarding the present blood levels of organochlorine residues in North Indian population with reference to reproductive health. The present study was designed to analyze the levels of organochlorine pesticide residues in maternal and cord blood samples of normal healthy women with full term pregnancy to gain insight into the current status of pesticide burden in newborns. Hexachlorocyclohexane (HCH) contributed maximum towards the total organochlorine residues present in maternal and cord blood followed by endosulfan, pp' DDE and pp' DDT being the least. This is also the first report indicating endosulfan levels in this population. Our data indicates a transfer rate of 60-70% of these pesticides from mothers to newborns and this high rate of transfer of pesticides is of great concern as it may adversely affect the growth and development of newborn.
authors.affiliation: Department of Biochemistry, University College of Medical Sciences, Dilshad Garden, Delhi, 110 095, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Pathak
authors.forename: Sanvidhan G
authors.initials: SG
authors.lastname: Suke
authors.forename: Rafat S
authors.initials: RS
authors.lastname: Ahmed
authors.forename: A K
authors.initials: AK
authors.lastname: Tripathi
authors.forename: Kiran
authors.initials: K
authors.lastname: Guleria
authors.forename: C S
authors.initials: CS
authors.lastname: Sharma
authors.forename: S D
authors.initials: SD
authors.lastname: Makhijani
authors.forename: Meenu
authors.initials: M
authors.lastname: Mishra
authors.forename: B D
authors.initials: BD
authors.lastname: Banerjee
mesh_terms: D000328:Adult; D004726:Endosulfan / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007306:Insecticides / Q000097:blood*; D010573:Pesticide Residues / Q000097:blood*; D011247:Pregnancy
chemical_list: D007306:Insecticides; D010573:Pesticide Residues; D004726:Endosulfan