title: Resveratrol: an original mechanism on tyrosinase inhibition.
abstract: This paper forms part of studies searching for new bioactive ingredients for cosmetics, for example, in the whitening agent field. The aim of our work was to present resveratrol as an original substrate for tyrosinase with very promising cosmetic perspectives. This study was based on several spectrophotometric analyses with minor adaptations. These analyses suggested that resveratrol is biotransformed by tyrosinase into an oxydated form, becoming a powerful inhibitor of tyrosinase. Furthermore, we show that resveratrol can be used as an additive compound in whitening cosmetics, particularly with a Morus alba extract. These results may help in understanding tyrosinase active site structure and mechanism.
authors.affiliation: Greentech S. A., Biopôle Clermont Limagne, 63360 Saint Beauzire Cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: J Y
authors.initials: JY
authors.lastname: Berthon