Coronary stenting with MGuard: from conception to human trials.
MGuard is an ultra-thin polymer sleeve attached to the external surface stents. The polymer was designed to reduce distal embolization during coronary, renal, carotid, and vein graft stenting, and to potentially serve as a platform for uniform drug delivery. This report discusses the theoretical considerations that resulted in the conception of this device, and the scientific data that support the use of the innovation. With the encouraging initial feasibility and safety data, large-scale efficacy trials are currently in progress. Future applications of this platform for the treatment of cardiovascular disorders are discussed.
Kaluski
Edo
E
Department of Cardiology, University Medical Center, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USA. kalusked@umdnj.edu
Tsai
Steve
S
Klapholz
Marc
M
D000818:Animals; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology; D004617:Embolism / Q000209:etiology / Q000517:prevention & control*; D004867:Equipment Design; D004869:Equipment Safety; D006801:Humans; D006965:Hyperplasia; D011093:Polyethylene Terephthalates; D015607:Stents / Q000009:adverse effects; D017539:Tunica Intima / Q000473:pathology
D011093:Polyethylene Terephthalates