title: [Lyme borreliosis in adults].
abstract: BACKGROUND
  Lyme borreliosis is a MULTISYSTEM: tick-borne infection caused by the spirochete Borrelia burgdorferi. We present a survey of clinical stages, diagnosis, treatment and prognosis of Lyme borreliosis in adults.
  
  
  METHODS
  The article is based on literature retrieved through database searches and own experience.
  
  
  CONCLUSIONS
  In Norway, Lyme borreliosis is most prevalent in coastal areas from the south and up to Trøndelag. Lyme disease can be classified into three stages; localised stage, and early and late disseminated stages. A laboratory gold standard does not exist, so the diagnosis is based on a combination of clinical manifestations and indirect detection of the bacteria, most often specific antibodies. Antibody results must be interpreted with caution. No medication is needed after a tick bite, but all manifestations of Lyme borreliosis should be treated with antibiotics according to guidelines. The prognosis is generally good. Post Lyme disease with persistent symptoms after borreliosis is a controversial condition. No studies have demonstrated persistent infection with borrelia bacteria in patients with chronic complaints after adequate antibiotic treatment, and additional antibiotic treatment does not improve quality of life in these patients.
authors.affiliation: Nevrologisk avdeling, Sørlandet Sykehus Kristiansand, Serviceboks 416, 4604 Kristiansand. unn.ljostad@sshf.no
authors.forename: Unn
authors.initials: U
authors.lastname: Ljøstad
authors.forename: Ase
authors.initials: A
authors.lastname: Mygland
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000907:Antibodies, Bacterial / Q000032:analysis; D025065:Borrelia burgdorferi / Q000276:immunology; D002443:Ceftriaxone / Q000008:administration & dosage; D004318:Doxycycline / Q000008:administration & dosage; D015787:Erythema Chronicum Migrans / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D020852:Lyme Neuroborreliosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D009664:Norway / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D011379:Prognosis
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D002443:Ceftriaxone; D004318:Doxycycline