title: Leiomyosarcoma of the urinary bladder in a patient with bilateral retinoblastoma.
abstract: We report a case of bladder leiomyosarcoma in a 27-year-old woman who had previously been treated with surgery and radiation for bilateral retinoblastoma. The patient was admitted to hospital with discomfort on micturition. Cystoscopy revealed a bladder tumor covered by normal urothelium. Transurethral resection of the bladder tumor was performed, and the histopathological diagnosis was leiomyosarcoma. Partial cystectomy was performed. The leiomyosarcoma of the bladder did not invade the muscle layer. However, bladder tumors recurred at new intravesical locations repeatedly. After transurethral resection of the bladder tumor had been performed twice, total cystectomy and creation of an ileal conduit were performed.
authors.affiliation: Department of Urology, Nagano Municipal Hospital, Nagano, Japan. minagaaa@hsp.md.shinshu-u.ac.jp
authors.forename: Tomonori
authors.initials: T
authors.lastname: Minagawa
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Okaneya
authors.forename: Muneyuki
authors.initials: M
authors.lastname: Kamigaito
authors.forename: Shuji
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Ogawa
authors.forename: Masako
authors.initials: M
authors.lastname: Kawakami
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Nakayama
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Imamura
authors.forename: Haruaki
authors.initials: H
authors.lastname: Kato
authors.forename: Osamu
authors.initials: O
authors.lastname: Nishizawa
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis*; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D019572:Retinal Neoplasms / Q000628:therapy*; D012175:Retinoblastoma / Q000628:therapy*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*