Chimeric (alpha-amino acid + nucleoside-beta-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition.
An alpha/beta-peptide backbone oligonucleotide comprising natural alpha-amino acids alternating with a beta-amino acid component derived from thymidine sequence specifically recognizes and binds to deoxy- and ribo-oligoadenylates in triplex mode.
Gogoi
Khirud
K
Division of Organic Chemistry, National Chemical Laboratory, Pune, 411008, India. k.gogoi@ncl.res.in
Kumar
Vaijayanti A
VA
D000596:Amino Acids / Q000737:chemistry*; D001667:Binding, Competitive; D004247:DNA / Q000737:chemistry*; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*; D013936:Thymidine / Q000737:chemistry
D000596:Amino Acids; D009705:Nucleosides; D010455:Peptides; D012313:RNA; D004247:DNA; D013936:Thymidine