title: Anaesthesia for Angelman syndrome.
abstract: We describe the administration of anaesthesia to a patient with Angelman syndrome, which is characterised by an abnormality of chromosome 15, where a subunit of the GABA receptor is coded. This has far-reaching anaesthetic implications as many drugs used in anaesthesia are thought to act via GABA receptors. Our patient had an uneventful peri-operative period and was discharged home on the second postoperative day.
authors.affiliation: Department of Anaesthetics, Prince Charles Hospital, Merthyr Tydfil, UK. krramanathan@yahoo.com
authors.forename: K R
authors.initials: KR
authors.lastname: Ramanathan
authors.forename: D
authors.initials: D
authors.lastname: Muthuswamy
authors.forename: B J
authors.initials: BJ
authors.lastname: Jenkins
mesh_terms: D000769:Anesthesia, Inhalation / Q000379:methods*; D017204:Angelman Syndrome / Q000235:genetics / Q000601:surgery*; D002675:Child, Preschool; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics; D006801:Humans; D008297:Male; D018079:Receptors, GABA / Q000235:genetics; D013363:Submandibular Gland / Q000601:surgery
chemical_list: D018079:Receptors, GABA