title: Bordetella hinzii septicemia in association with Epstein-Barr virus viremia and an Epstein-Barr virus-associated diffuse large B-cell lymphoma.
abstract: We report the 1st case of Bordetella hinzii septicemia associated with Epstein-Barr virus viremia and lymphoma. B. hinzii identification necessitated cellular fatty acid analysis by gas-liquid chromatography and 16S rRNA gene sequencing. Isolates were resistant to many antimicrobials. Resistance and diagnostic challenges complicated management and contributed to mortality.
authors.affiliation: Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA. acappie1@jhmi.edu
authors.forename: Alexandra C
authors.initials: AC
authors.lastname: Hristov
authors.forename: Paul G
authors.initials: PG
authors.lastname: Auwaerter
authors.forename: Mark
authors.initials: M
authors.lastname: Romagnoli
authors.forename: Karen C
authors.initials: KC
authors.lastname: Carroll
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D001884:Bordetella / Q000737:chemistry / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D001885:Bordetella Infections / Q000175:diagnosis*; D004269:DNA, Bacterial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000276:immunology; D017809:Fatal Outcome; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D020459:Genes, rRNA; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000821:virology*; D008826:Microbial Sensitivity Tests; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D018805:Sepsis / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D014766:Viremia / Q000276:immunology / Q000821:virology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D005227:Fatty Acids; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S