title: Early elevation of intra-abdominal pressure after laparotomy for secondary peritonitis: a predictor of relaparotomy?
abstract: BACKGROUND
  Patients with secondary peritonitis often require relaparotomy; however, there is no consensus about the criteria for selecting patients who would benefit from early relaparotomy. Our goal was to evaluate whether elevated intra-abdominal pressure (IAP) during the early postoperative period could predict the need for relaparotomy.
  
  
  METHODS
  A total of 102 consecutive adult patients with acute intra-abdominal conditions were admitted for laparotomy. Seventy-eight patients, who were diagnosed with secondary peritonitis at index surgery, underwent serial measurements of IAP. The primary outcomes measured in the study were incidence of postoperative peritonitis and mortality.
  
  
  RESULTS
  Thirty-two of 78 patients with secondary peritonitis (41%) developed elevated IAP postoperatively. Sixteen (20.5%) of 78 patients developed postoperative peritonitis. Twelve of these 16 patients (75%) with postoperative peritonitis had significantly elevated IAP (P = 0.002) during the immediate postoperative period. Regression analysis revealed elevated IAP (P = 0.055) to be third most predictive of postoperative peritonitis in patients who underwent laparotomy for secondary peritonitis, after septic shock at admission (P = 0.012) and POSSUM score (P = 0.018).
  
  
  CONCLUSIONS
  Our study shows that development of elevated IAP during the early postoperative period can increase the risk of postoperative peritonitis. IAP measured during the immediate postoperative period can be used as a predictor of early relaparotomy.
authors.affiliation: Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. adhishbasu@rediffmail.com
authors.forename: Adhish
authors.initials: A
authors.lastname: Basu
authors.forename: Dinker R
authors.initials: DR
authors.lastname: Pai
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D015994:Incidence; D007813:Laparotomy; D016015:Logistic Models; D008297:Male; D018579:Patient Selection; D010538:Peritonitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D011237:Predictive Value of Tests; D011312:Pressure; D011446:Prospective Studies; D012086:Reoperation; D012307:Risk Factors; D012720:Severity of Illness Index