title: Weil's disease in a patient with chronic viral hepatitis and history of alcohol abuse.
abstract: Clinical and laboratory diagnosis of severe leptospirosis (Weil's disease) may be difficult when other pathological processes that may cause similar clinical syndromes or affect immune response to infections coexist. In addition, the optimal management of the disease remains to be defined. We report on a case of Weil's disease, in which concurrent chronic hepatitis B virus infection and alcohol abuse caused diagnostic and therapeutic difficulties.
authors.affiliation: The 1st Division of Internal Medicine, University Hospital, Ioannina, Greece.
authors.forename: Leonidas
authors.initials: L
authors.lastname: Christou
authors.forename: Georgios
authors.initials: G
authors.lastname: Kalambokis
authors.forename: Epameinondas V
authors.initials: EV
authors.lastname: Tsianos
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000437:Alcoholism / Q000150:complications / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002439:Cefotaxime / Q000627:therapeutic use; D019694:Hepatitis B, Chronic / Q000150:complications / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D012698:Serologic Tests; D014895:Weil Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D002439:Cefotaxime