[Biocompatibility study of polylactic/glycolic acid and Schwann cell].
OBJECTIVE
To examine the biocompatibility of polylactic/glycolic acid (PLGA) and Schwann cells.


METHODS
Schwann cells were harvested from rat brachial and sciatic nerves. Schwann cells were cultured with PLGA, observed by phase-contrast microscopy and electron microscopy.


RESULTS
Schwann cells could attach and proliferate on the surface of the PLGA.


CONCLUSIONS
The PLGA has good cellular biocompatibility. It can be used as biomaterial for tissue engineering.
Du
Huaidong
H
Department of Otorhinolaryngology, Affiliated Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.
Tian
Hongbin
H
Zhou
Liang
L
Tian
Jie
J
D000818:Animals; D001672:Biocompatible Materials; D002478:Cells, Cultured; D019344:Lactic Acid; D009416:Nerve Regeneration; D011091:Polyesters; D011100:Polyglycolic Acid; D011108:Polymers; D051381:Rats; D017207:Rats, Sprague-Dawley; D012583:Schwann Cells / Q000166:cytology / Q000276:immunology*
D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D011100:Polyglycolic Acid; D019344:Lactic Acid; C033616:poly(lactide)