Familial cholesteatoma in East Anglia, UK.
OBJECTIVE
To report a cluster of families affected by cholesteatoma in the East Anglia region of the UK.


METHODS
Otology service for the population of Norfolk and North Suffolk, East Anglia, UK.


METHODS
Prospective and systematic collection of family history data for patients presenting with cholesteatoma over 10 years.


RESULTS
Several families were identified with affected individuals over several generations.


CONCLUSIONS
There is likely to be a genetic propensity for cholesteatoma in some individuals.
Prinsley
P
P
Department of Otolaryngology and Head and Neck Surgery, James Paget and Norfolk and Norwich University Hospitals, UK. prinsley@mac.com
D000328:Adult; D002648:Child; D018424:Cholesteatoma, Middle Ear / Q000453:epidemiology / Q000235:genetics*; D016000:Cluster Analysis; D004739:England / Q000453:epidemiology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D010375:Pedigree; D011446:Prospective Studies