Quantitative expediency assessment of the zeta sedimentation ratio and the plasma viscosity in arterial hypertension research.
Accepted methods of the ESR methodology (the Westergren mode and ZSR mode) and its alternative the plasma viscosity were tested for diagnostic utility in pregnancy induced hypertension and pre-eclampsia. The receiver-operating characteristic curve (ROC) analysis approved moderate diagnostic accuracy for the ESR methodology and supplied support for its preliminary estimated cutoff values but failed to indicate cogent discernment of pathology by values of plasma viscosity. Likely pathological whole blood alterations boost the erythrocyte aggregation while the concomitant depletion of macromolecules degrades plasma viscosity values.
Stoeff
S
S
Department of Physics and Biophysics, Medical Faculty, Medical University Sofia, Sofia, Bulgaria. stoeff@medfac.acad.bg
Jovtchev
Sv
S
Dikov
I
I
Kolarov
D
D
Galabova
T
T
Trifonova
N
N
Hadjieva
Sv
S
Mladenova
A
A
Lambreva
L
L
Penev
M
M
D019540:Area Under Curve; D001158:Arteries / Q000473:pathology; D001799:Blood Sedimentation; D001809:Blood Viscosity; D004903:Erythrocyte Aggregation; D005260:Female; D018056:Hemorheology / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000097:blood*; D011225:Pre-Eclampsia; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D012372:ROC Curve; D012044:Regression Analysis