title: Wagner-Meissner neurilemmoma of the right cheek.
abstract: We report a very rare case of Wagner-Meissner neurilemmoma in the cheek of a 10-year-old boy. The tumor presented as a slowly growing soft tissue swelling. Magnetic resonance imaging disclosed a very infiltrative, 9-cm mass involving the subcutis and deep soft tissues of the right cheek. Microscopically, the tumor was unencapsulated and composed almost entirely of well-formed Wagner-Meissner corpuscles that formed confluent sheets, perivascular cuffs, and individual corpuscles percolating through adipose tissue. Compared with the 3 previous reports, which describe circumscribed, encapsulated tumors in adult patients, this case had distinctive clinicopathologic features never reported: presentation in a pediatric patient, location in the head and neck region, and an infiltrative growth pattern.
authors.affiliation: Department of Pathology, University of Michigan, MI 48109-0054, USA.
authors.forename: Angela J
authors.initials: AJ
authors.lastname: Wu
authors.forename: Jason
authors.initials: J
authors.lastname: Jarzembowski
authors.forename: Yoav
authors.initials: Y
authors.lastname: Morag
authors.forename: David R
authors.initials: DR
authors.lastname: Lucas
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002610:Cheek / Q000473:pathology*; D002648:Child; D005153:Facial Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008465:Mechanoreceptors / Q000737:chemistry / Q000473:pathology*; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D009418:S100 Proteins