An unusual case of aldosterone- and norepinephrine-secreting retroperitoneal leiomyosarcoma.
A case of retroperitoneal leiomyosarcoma (LMS) in a 38-year-old woman who had a tumor in the retroperitoneum with severe hypertension and hypokalemia is presented. Further investigation revealed an elevated serum aldosterone and norepinephrine level. After tumorectomy, the levels of serum aldosterone and norepinephrine successfully normalized; hypertension and hypokalemia were also cured. The tumor was diagnosed as being a LMS by pathologic examination. We suggested that this was the first case of retroperitoneal LMS shown to be associated with increased levels of serum aldosterone and norepinephrine.
Wu
Y-Y
YY
Department of Urology, West China Hospital, Sichuan University, Chengdu, PR China.
Wei
Q
Q
Zeng
H
H
Chen
H-J
HJ
Li
H
H
Lin
H
H
Li
X
X
D000328:Adult; D000450:Aldosterone / Q000378:metabolism*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D009638:Norepinephrine / Q000378:metabolism*; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
D000450:Aldosterone; D009638:Norepinephrine