Surfactant treatment of an infant with acute idiopathic pulmonary hemorrhage.
OBJECTIVE
To describe the successful use of surfactant for treatment of respiratory distress refractory to conventional mechanical ventilation in a 4-wk-old with pulmonary hemorrhage.


METHODS
Case report.


METHODS
Tertiary care center pediatric intensive care unit.


METHODS
Four-week-old infant.


RESULTS
Clinical improvement of respiratory distress as evidenced by 50% reduction in oxygenation index and subsequent extubation.


CONCLUSIONS
Pulmonary hemorrhage is a rare but potentially fatal condition in children. Previously described therapeutic approaches include high-frequency oscillation ventilation and extracorporeal membrane oxygenation. Infants with pulmonary hemorrhage and respiratory distress may benefit from a trial of surfactant before escalating care.
Neumayr
Tara M
TM
Department of Pediatrics, Mayo Clinic College of Medicine, Rochester, MN, USA.
Watson
Andrea M
AM
Wylam
Mark E
ME
Ouellette
Yves
Y
D006470:Hemorrhage / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D008171:Lung Diseases / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D011650:Pulmonary Alveoli / Q000187:drug effects; D011663:Pulmonary Surfactants / Q000494:pharmacology / Q000627:therapeutic use*; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D016896:Treatment Outcome
D011663:Pulmonary Surfactants