title: 2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosa quorum sensing modulator.
abstract: Diastereomeric 2-methoxycyclopentyl analogues of a natural quorum sensing signaling molecule from Pseudomonas aeruginosa were synthesized and screened in pigment production assays with P. aeruginosa and Serratia strain ATCC39006.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
authors.forename: Lydia Y W
authors.initials: LY
authors.lastname: Lee
authors.forename: Timothy
authors.initials: T
authors.lastname: Hupfield
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Nicholson
authors.forename: James T
authors.initials: JT
authors.lastname: Hodgkinson
authors.forename: Xianbin
authors.initials: X
authors.lastname: Su
authors.forename: Gemma L
authors.initials: GL
authors.lastname: Thomas
authors.forename: George P C
authors.initials: GP
authors.lastname: Salmond
authors.forename: Martin
authors.initials: M
authors.lastname: Welch
authors.forename: David R
authors.initials: DR
authors.lastname: Spring
mesh_terms: D001665:Binding Sites; D004305:Dose-Response Relationship, Drug; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000502:physiology*; D053038:Quorum Sensing / Q000187:drug effects*; D012705:Serratia / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship