title: Newly developed hypertension as an early marker of recurrence of adrenocortical carcinoma with high renin expression.
abstract: Adrenocortical carcinoma can recur frequently after successful surgery but no adequate markers can detect this recurrence. Here, we present a recurrence of adrenocortical carcinoma with a high renin expression, after successful surgery, where hypertension has developed again. Tumor recurrence was observed via (18)F-fluorodeoxyglucose positron emission tomography and coregistered computed tomography. Based on our findings, follow-up blood pressure assessment may effectively predict the recurrence of adrenocortical carcinoma.
authors.affiliation: Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Min-Jie
authors.initials: MJ
authors.lastname: Wen
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Lin
authors.forename: Jin-Shuen
authors.initials: JS
authors.lastname: Chen
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism*; D018268:Adrenocortical Carcinoma / Q000150:complications* / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications* / Q000378:metabolism*; D012083:Renin / Q000096:biosynthesis*
chemical_list: D012083:Renin