title: Isolation and characterization of a novel Francisella sp. from human cerebrospinal fluid and blood.
abstract: We describe the isolation of a Francisella sp. from normally sterile sites in acutely ill patients in two different states within 2 years. Microbiologic and molecular analyses indicate that this organism represents a novel Francisella sp. Clinicians and microbiologists should be aware of this new potential pathogen, as infection may be more common than recognized.
authors.affiliation: Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, Colorado 80521, USA.
authors.forename: Kiersten J
authors.initials: KJ
authors.lastname: Kugeler
authors.forename: Paul S
authors.initials: PS
authors.lastname: Mead
authors.forename: Karin L
authors.initials: KL
authors.lastname: McGowan
authors.forename: Jon M
authors.initials: JM
authors.lastname: Burnham
authors.forename: Michael D
authors.initials: MD
authors.lastname: Hogarty
authors.forename: Eduardo
authors.initials: E
authors.lastname: Ruchelli
authors.forename: Kerry
authors.initials: K
authors.lastname: Pollard
authors.forename: Brigitte
authors.initials: B
authors.lastname: Husband
authors.forename: Caryn
authors.initials: C
authors.lastname: Conley
authors.forename: Tanya
authors.initials: T
authors.lastname: Rivera
authors.forename: Theodoros
authors.initials: T
authors.lastname: Kelesidis
authors.forename: Walter M
authors.initials: WM
authors.lastname: Lee
authors.forename: Walburga
authors.initials: W
authors.lastname: Mabey
authors.forename: Jonas M
authors.initials: JM
authors.lastname: Winchell
authors.forename: Heather L
authors.initials: HL
authors.lastname: Stang
authors.forename: J Erin
authors.initials: JE
authors.lastname: Staples
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Chalcraft
authors.forename: Jeannine M
authors.initials: JM
authors.lastname: Petersen
mesh_terms: D000369:Aged, 80 and over; D000372:Agglutination Tests; D016470:Bacteremia / Q000382:microbiology; D015373:Bacterial Typing Techniques; D001769:Blood / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D005603:Francisella / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008590:Meningoencephalitis / Q000382:microbiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S