Racial differences in prostate cancer screening by family history.
OBJECTIVE
Prostate cancer (CaP) is disproportionately prevalent among black, compared to white, men. Additionally, men with a family history of CaP have 75% to 80% higher risk of CaP. Therefore we examined racial variation in the association of family history of CaP and self-reported prostate-specific antigen (PSA) testing in the nationally-representative National Health Interview Survey (NHIS).


METHODS
Data were obtained from the 2005 NHIS, including the Cancer Control Module supplement. We restricted the study sample to men over the age of 40 who reported having "ever heard of a PSA test" (N = 1,744). Men were considered to have a positive family history if either their biological father or at least one biological brother had been diagnosed with CaP. SUDAAN 9.0 was used to perform descriptive and multivariable logistic regression analyses.


RESULTS
Men with a family history of CaP were more likely to have a PSA test than those who never had a PSA test (odds ratio [OR] = 1.8; 95% confidence interval [CI]: 1.3-2.5). Among blacks, men with a family history were not significantly more likely to have a PSA test.


CONCLUSIONS
Despite having the highest risk of cancer, black men with a family history are not screened more than black men without a family history.
Drake
Bettina F
BF
Department of Society, Human Development and Health, Center for Community-Based Research, Harvard School of Public Health, Boston, MA, USA. bettina_drake@dfci.harvard.edu
Lathan
Christopher S
CS
Okechukwu
Cassandra A
CA
Bennett
Gary G
GG
D000328:Adult; D001741:Black or African American; D000368:Aged; D001294:Attitude to Health / Q000208:ethnology; D005192:Family Health; D020022:Genetic Predisposition to Disease; D007722:Health Knowledge, Attitudes, Practice; D006306:Health Surveys; D054625:Healthcare Disparities; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data; D008875:Middle Aged; D015995:Prevalence; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000208:ethnology* / Q000235:genetics; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D044465:White People
D017430:Prostate-Specific Antigen