Development of Novel DNA Cleavage Systems Based on Copper Complexes. Synthesis and Characterisation of Cu(II) Complexes of Hydroxyflavones.
Copper(II) complexes of several hydroxyflavones were prepared and characterised through their physico-chemical properties. The nuclease activity of three synthesised complexes is reported. These copper(II) complexes present more nuclease activity than the ligands and the copper(II) ion.
El Amrani
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Department of Inorganic Chemistry University of Valencia Faculty of Pharmacy Vicent Andrés Estellés s/n Burjassot (Valencia) E- 46100 Spain.
Perelló
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Borrás
J
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Torres
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