Mycoplasma pneumoniae: nervous system complications in childhood and review of the literature.
Mycoplasma pneumoniae is an important pathogen which causes nervous system disorders during or after the course of a respiratory tract infection. The exact pathogenic mechanism which causes neurological disorders still remains unknown. Although meningoencephalitis and acute disseminated encephalomyelitis are common complications, there are few cases of acute transverse myelitis and isolated abducens nerve palsy associated with M. pneumoniae infection in childhood. The association between ocular myasthenia gravis and M. pneumoniae infection has not been described before. Here, we describe five patients with different nervous system complications associated with M. pneumoniae infection and discuss the pathological features of central nervous system involvement.
Yiş
Uluç
U
Department of Pediatrics, Division of Child Neurology, Dokuz Eylül University School of Medicine, 35340, Izmir, Turkey. ulyis@yahoo.com
Kurul
Semra Hiz
SH
Cakmakçi
Handan
H
Dirik
Eray
E
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001763:Blepharoptosis / Q000188:drug therapy / Q000382:microbiology; D002648:Child; D004673:Encephalomyelitis, Acute Disseminated / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000188:drug therapy / Q000382:microbiology / Q000503:physiopathology*; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification / Q000472:pathogenicity*; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D011019:Pneumonia, Mycoplasma / Q000150:complications*
D000900:Anti-Bacterial Agents