title: [Adjunct use of NovoSeven (recombinant factor VIIa) for penetrating cardiac trauma].
abstract: BACKGROUND
  Uncontrolled bleeding leads to 40-86% of preventable deaths due to trauma. Use of NovoSeven (rFVIIa) in trauma is promising, although data supporting its utilization are limited.
  
  
  METHODS
  We report the case of a patient who sustained a penetrating grade V cardiac injury (AAST-OIS) and presented postoperative massive coagulopathic bleeding arrested by the administration of platelet pools and NovoSeven.
  
  
  CONCLUSIONS
  This report represents our initial experience and the very first case of successful use of NovoSeven for the treatment of traumatic coagulopathic hemorrhage at the Central Military Hospital in Mexico City. A further prospective trial justifying its use in our institution is warranted.
authors.affiliation: Subsección de Cirugía del Trauma, Departamento de Cirugía, Hospital Central Militar, Secretaría de la Defensa Nacional, México, D.F., Mexico. lmgarcian@hotmail.com
authors.forename: Luis Manuel
authors.initials: LM
authors.lastname: García-Núñez
authors.forename: Luis Enrique
authors.initials: LE
authors.lastname: Soto-Ortega
authors.forename: Ruy
authors.initials: R
authors.lastname: Cabello-Pasini
authors.forename: Luis Enrique
authors.initials: LE
authors.lastname: Payró-Hernández
authors.forename: Ignacio Javier
authors.initials: IJ
authors.lastname: Magaña-Sánchez
mesh_terms: D000007:Abdominal Injuries / Q000601:surgery; D000328:Adult; D000435:Alcoholic Intoxication / Q000150:complications; D016913:Blood Component Transfusion; D003131:Combined Modality Therapy; D004322:Drainage; D004630:Emergencies; D015942:Factor VIIa / Q000627:therapeutic use*; D006335:Heart Injuries / Q000150:complications* / Q000601:surgery; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D009104:Multiple Trauma / Q000601:surgery; D011994:Recombinant Proteins / Q000627:therapeutic use; D013908:Thoracotomy; D014951:Wounds, Stab / Q000150:complications* / Q000601:surgery
chemical_list: D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa