title: A new method for the determination of aortic pulse wave velocity using cross-correlation on 2D PCMR velocity data.
abstract: OBJECTIVE
  To evaluate the reproducibility of a new multisite axial pulse wave velocity (PWV) measurement technique that makes use of 2D PCMR data and cross-correlation analysis.
  
  
  METHODS
  PWV was estimated with MRI in 13 healthy volunteers by a transit-time technique (TT), a multisite technique utilizing 1D PCMR data in the descending aorta (FOOT), and a new multisite axial technique that uses 2D PCMR data over the ascending, transverse, and descending sections of the aorta (2D-XC).
  
  
  RESULTS
  No significant difference was observed between PWV measurements values measured by the three techniques. However, 2D-XC displayed significantly better intertest reproducibility than either the TT or FOOT methodologies. Average percent difference between scans: TT: 15.8% +/- 13.4%, FOOT: 21.3% +/- 16.9%, 2D-XC: 7.72% +/- 4.73%. P = 0.02 for both 2D-XC/TT comparison and 2D-XC/FOOT comparison.
  
  
  CONCLUSIONS
  2D-XC is a more reproducible method than either the established TT or FOOT methods to estimate the aortic PWV.
authors.affiliation: Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
authors.forename: Samuel W
authors.initials: SW
authors.lastname: Fielden
authors.forename: Brandon K
authors.initials: BK
authors.lastname: Fornwalt
authors.forename: Michael
authors.initials: M
authors.lastname: Jerosch-Herold
authors.forename: Robert L
authors.initials: RL
authors.lastname: Eisner
authors.forename: Arthur E
authors.initials: AE
authors.lastname: Stillman
authors.forename: John N
authors.initials: JN
authors.lastname: Oshinski
mesh_terms: D000328:Adult; D001013:Aorta, Thoracic / Q000033:anatomy & histology / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011673:Pulsatile Flow / Q000502:physiology*; D012016:Reference Values; D015203:Reproducibility of Results