A new method for the determination of aortic pulse wave velocity using cross-correlation on 2D PCMR velocity data.
OBJECTIVE
To evaluate the reproducibility of a new multisite axial pulse wave velocity (PWV) measurement technique that makes use of 2D PCMR data and cross-correlation analysis.


METHODS
PWV was estimated with MRI in 13 healthy volunteers by a transit-time technique (TT), a multisite technique utilizing 1D PCMR data in the descending aorta (FOOT), and a new multisite axial technique that uses 2D PCMR data over the ascending, transverse, and descending sections of the aorta (2D-XC).


RESULTS
No significant difference was observed between PWV measurements values measured by the three techniques. However, 2D-XC displayed significantly better intertest reproducibility than either the TT or FOOT methodologies. Average percent difference between scans: TT: 15.8% +/- 13.4%, FOOT: 21.3% +/- 16.9%, 2D-XC: 7.72% +/- 4.73%. P = 0.02 for both 2D-XC/TT comparison and 2D-XC/FOOT comparison.


CONCLUSIONS
2D-XC is a more reproducible method than either the established TT or FOOT methods to estimate the aortic PWV.
Fielden
Samuel W
SW
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Fornwalt
Brandon K
BK
Jerosch-Herold
Michael
M
Eisner
Robert L
RL
Stillman
Arthur E
AE
Oshinski
John N
JN
D000328:Adult; D001013:Aorta, Thoracic / Q000033:anatomy & histology / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011673:Pulsatile Flow / Q000502:physiology*; D012016:Reference Values; D015203:Reproducibility of Results