title: Land use regression modeling of intra-urban residential variability in multiple traffic-related air pollutants.
abstract: BACKGROUND
  There is a growing body of literature linking GIS-based measures of traffic density to asthma and other respiratory outcomes. However, no consensus exists on which traffic indicators best capture variability in different pollutants or within different settings. As part of a study on childhood asthma etiology, we examined variability in outdoor concentrations of multiple traffic-related air pollutants within urban communities, using a range of GIS-based predictors and land use regression techniques.
  
  
  METHODS
  We measured fine particulate matter (PM2.5), nitrogen dioxide (NO2), and elemental carbon (EC) outside 44 homes representing a range of traffic densities and neighborhoods across Boston, Massachusetts and nearby communities. Multiple three to four-day average samples were collected at each home during winters and summers from 2003 to 2005. Traffic indicators were derived using Massachusetts Highway Department data and direct traffic counts. Multivariate regression analyses were performed separately for each pollutant, using traffic indicators, land use, meteorology, site characteristics, and central site concentrations.
  
  
  RESULTS
  PM2.5 was strongly associated with the central site monitor (R2 = 0.68). Additional variability was explained by total roadway length within 100 m of the home, smoking or grilling near the monitor, and block-group population density (R2 = 0.76). EC showed greater spatial variability, especially during winter months, and was predicted by roadway length within 200 m of the home. The influence of traffic was greater under low wind speed conditions, and concentrations were lower during summer (R2 = 0.52). NO2 showed significant spatial variability, predicted by population density and roadway length within 50 m of the home, modified by site characteristics (obstruction), and with higher concentrations during summer (R2 = 0.56).
  
  
  CONCLUSIONS
  Each pollutant examined displayed somewhat different spatial patterns within urban neighborhoods, and were differently related to local traffic and meteorology. Our results indicate a need for multi-pollutant exposure modeling to disentangle causal agents in epidemiological studies, and further investigation of site-specific and meteorological modification of the traffic-concentration relationship in urban neighborhoods.
authors.affiliation: Harvard School of Public Health, Department of Environmental Health, Landmark Center 4th Floor West, PO Box 15677, Boston, MA 02215, USA. jcloughe@hsph.harvard.edu
authors.forename: Jane E
authors.initials: JE
authors.lastname: Clougherty
authors.forename: Rosalind J
authors.initials: RJ
authors.lastname: Wright
authors.forename: Lisa K
authors.initials: LK
authors.lastname: Baxter
authors.forename: Jonathan I
authors.initials: JI
authors.lastname: Levy
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D016902:Air Pollution, Indoor / Q000032:analysis*; D002244:Carbon / Q000032:analysis*; D002947:Cities; D004784:Environmental Monitoring / Q000706:statistics & numerical data*; D040362:Geographic Information Systems; D006798:Housing; D008404:Massachusetts; D008962:Models, Theoretical; D009585:Nitrogen Dioxide / Q000032:analysis*; D052638:Particulate Matter / Q000032:analysis*; D012044:Regression Analysis; D014504:Urban Health; D001335:Vehicle Emissions
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter; D001335:Vehicle Emissions; D002244:Carbon; D009585:Nitrogen Dioxide