Polyadenylation and degradation of mRNA in mammalian mitochondria: a missing link?
mRNA turnover in human mitochondria, one of the key mechanisms governing mitochondrial gene expression, still presents an unsolved puzzle. The present article summarizes the current research on the mechanisms and enzymes that may be involved in that process.
Bobrowicz
Agnieszka J
AJ
Mitochondrial Research Group, Institute of Neuroscience, Newcastle University, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Lightowlers
Robert N
RN
Chrzanowska-Lightowlers
Zofia
Z
D000818:Animals; D004272:DNA, Mitochondrial / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000378:metabolism*; D026723:Polyadenylation; D012323:RNA Processing, Post-Transcriptional; D020871:RNA Stability; D014158:Transcription, Genetic
D004272:DNA, Mitochondrial