title: Acute stroke imaging research roadmap.
abstract: The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.
authors.affiliation: Department of Radiology, University of California, San Francisco, CA 94143-0628, USA. Max.Wintermark@radiology.ucsf.edu
authors.forename: Max
authors.initials: M
authors.lastname: Wintermark
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Albers
authors.forename: Andrei V
authors.initials: AV
authors.lastname: Alexandrov
authors.forename: Jeffry R
authors.initials: JR
authors.lastname: Alger
authors.forename: Roland
authors.initials: R
authors.lastname: Bammer
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Baron
authors.forename: Stephen
authors.initials: S
authors.lastname: Davis
authors.forename: Bart M
authors.initials: BM
authors.lastname: Demaerschalk
authors.forename: Colin P
authors.initials: CP
authors.lastname: Derdeyn
authors.forename: Geoffrey A
authors.initials: GA
authors.lastname: Donnan
authors.forename: James D
authors.initials: JD
authors.lastname: Eastwood
authors.forename: Jochen B
authors.initials: JB
authors.lastname: Fiebach
authors.forename: Marc
authors.initials: M
authors.lastname: Fisher
authors.forename: Karen L
authors.initials: KL
authors.lastname: Furie
authors.forename: Gregory V
authors.initials: GV
authors.lastname: Goldmakher
authors.forename: Werner
authors.initials: W
authors.lastname: Hacke
authors.forename: Chelsea S
authors.initials: CS
authors.lastname: Kidwell
authors.forename: Stephan P
authors.initials: SP
authors.lastname: Kloska
authors.forename: Martin
authors.initials: M
authors.lastname: Köhrmann
authors.forename: Walter
authors.initials: W
authors.lastname: Koroshetz
authors.forename: Ting-Yim
authors.initials: TY
authors.lastname: Lee
authors.forename: Kennedy R
authors.initials: KR
authors.lastname: Lees
authors.forename: Michael H
authors.initials: MH
authors.lastname: Lev
authors.forename: David S
authors.initials: DS
authors.lastname: Liebeskind
authors.forename: Leif
authors.initials: L
authors.lastname: Ostergaard
authors.forename: William J
authors.initials: WJ
authors.lastname: Powers
authors.forename: James
authors.initials: J
authors.lastname: Provenzale
authors.forename: Peter
authors.initials: P
authors.lastname: Schellinger
authors.forename: Robert
authors.initials: R
authors.lastname: Silbergleit
authors.forename: Alma Gregory
authors.initials: AG
authors.lastname: Sorensen
authors.forename: Joanna
authors.initials: J
authors.lastname: Wardlaw
authors.forename: Ona
authors.initials: O
authors.lastname: Wu
authors.forename: Steven
authors.initials: S
authors.lastname: Warach
mesh_terms: D000208:Acute Disease; D035843:Biomedical Research / Q000639:trends*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D009485:Neuroradiography / Q000639:trends*; D010818:Practice Patterns, Physicians' / Q000639:trends*; D012106:Research / Q000639:trends*; D020521:Stroke / Q000175:diagnosis*; D014481:United States