title: Intensive care unit variables and outcome after pediatric traumatic brain injury: a retrospective study of survivors.
abstract: OBJECTIVE
  Traumatic brain injury is a leading cause of death and disability in children. Hypotension has been associated with poor survival and outcome in children after traumatic brain injury, but the effect of acute hypertension is less certain. The objective was to obtain acute physiologic variables during the early hospitalization period in a cohort of children prospectively enrolled in another study.
  
  
  METHODS
  Retrospective chart reviews.
  
  
  METHODS
  University-affiliated pediatric rehabilitation center.
  
  
  METHODS
  Fifty-seven survivors, 5-17 yrs of age, admitted for rehabilitation between 1992 and 1995 after sustaining a traumatic brain injury.
  
  
  METHODS
  Standard of care.
  
  
  RESULTS
  Outcomes were assessed at 1 yr postinjury through cognitive testing of the child and parent interview of the child's global functional skills. Cognitive outcome was measured using the Performance IQ from the Wechsler Intelligence Scale for Children, Third Edition. Overall functional outcome was assessed using the Disability Rating Scale.
  
  
  CONCLUSIONS
  This study suggests that early markers of secondary injury after moderate to severe traumatic brain injury in children may be predictive of long-term outcome. This study reinforces the need for longer term, systematic, and more precise measurements of outcomes in children with traumatic brain injury and prospective studies to examine the predictive value of acute management variables on multiple types of outcomes after traumatic brain injury in children.
authors.affiliation: Kennedy Krieger Institute, Baltimore, MD, USA. salorio@kennedykrieger.org
authors.forename: Cynthia F
authors.initials: CF
authors.lastname: Salorio
authors.forename: Beth S
authors.initials: BS
authors.lastname: Slomine
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Guerguerian
authors.forename: James R
authors.initials: JR
authors.lastname: Christensen
authors.forename: Jeanette R M
authors.initials: JR
authors.lastname: White
authors.forename: Joanne E
authors.initials: JE
authors.lastname: Natale
authors.forename: Donald H
authors.initials: DH
authors.lastname: Shaffner
authors.forename: Marco A
authors.initials: MA
authors.lastname: Grados
authors.forename: Roma A
authors.initials: RA
authors.lastname: Vasa
authors.forename: Joan P
authors.initials: JP
authors.lastname: Gerring
mesh_terms: D000293:Adolescent; D015142:Baltimore; D001930:Brain Injuries / Q000150:complications / Q000473:pathology* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008297:Male; D008485:Medical Audit; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D017741:Survivors; D016896:Treatment Outcome