title: Early Detection of Bronchial Lesions Using System of Autofluorescence Endoscopy (SAFE) 1000.
abstract: Recently several endoscopic fluorescence detection systems have been developed. In some of them, laser light was used for the excitation of autofluorescence, and sophisticated techniques were also necessary to amplify the fluorescence signal as well.The result of fluorescence diagnosis using a simple system with a conventional Xenon lamp excitation and an image intensifier is reported. The respective results of sensitivity and positive predictive values of cancer plus dysplasia were 66%, and 62% by standard bronchoscopy and 92% and 88% by the newly developed autofluorescence system. In this paper, developed endoscope for detection of tissue/mucosal autofluorescence without the application of any photosensitizing agents or use of any lasers is evaluated.
authors.affiliation: Department of Surgery Tokyo Medical University 6-7-1 Nishishinjuku Shinjuku-ku Tokyo 160-0023 Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kakihana
authors.forename: K K
authors.initials: KK
authors.lastname: Il
authors.forename: T
authors.initials: T
authors.lastname: Okunaka
authors.forename: K
authors.initials: K
authors.lastname: Furukawa
authors.forename: T
authors.initials: T
authors.lastname: Hirano
authors.forename: C
authors.initials: C
authors.lastname: Konaka
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: Y
authors.initials: Y
authors.lastname: Ebihara