Answer to comments by A. Lerchl on "Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes" published by C. Schwarz et al. 2008.
Genotoxic effects induced in vitro by the third generation mobile communication standard UMTS have recently been described by Schwarz et al. (Int Arch Occup Environ Health 81:755-767, 2008). These findings which may have considerable significance for environmental health have been commented upon by Lerchl (Int Arch Occup Environ Health in press, 2008) (this issue). These comments which are invalid in part have to be set right. Although some of his minor points are correct the objected inconsistencies are largely based on the author's incomplete and superficial consideration of published data in the field. Moreover, the statistical points being made cannot cast doubts on the validity of the experimental data reported by Schwarz et al. and may not change the principal conclusion of in vitro genotoxic action of UMTS signals.
Rüdiger
Hugo W
HW
Division of Occupational Medicine, Medical University of Vienna, Vienna, Austria. hugo.ruediger@meduniwien.ac.at
D000818:Animals; D015982:Bias; D040421:Cell Phone; D002478:Cells, Cultured; D020552:Comet Assay / Q000379:methods* / Q000706:statistics & numerical data; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000528:radiation effects; D004249:DNA Damage; D003627:Data Interpretation, Statistical; D004311:Double-Blind Method; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005347:Fibroblasts / Q000528:radiation effects*; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D048629:Micronuclei, Chromosome-Defective / Q000528:radiation effects* / Q000706:statistics & numerical data; D015162:Micronucleus Tests / Q000379:methods* / Q000706:statistics & numerical data; D051381:Rats; D015203:Reproducibility of Results
D004247:DNA