Direct involvement of type II secretion system in extracellular translocation of Shewanella oneidensis outer membrane cytochromes MtrC and OmcA.
MtrC and OmcA are cell surface-exposed lipoproteins important for reducing solid metal oxides. Deletions of type II secretion system (T2SS) genes reduced their extracellular release and their accessibility to the proteinase K treatment, demonstrating the direct involvement of T2SS in translocation of MtrC and OmcA to the bacterial cell surface.
Shi
Liang
L
Microbiology Group, Pacific Northwest National Laboratory, Richland, Washington 99354, USA. liang.shi@pnl.gov
Deng
Shuang
S
Marshall
Matthew J
MJ
Wang
Zheming
Z
Kennedy
David W
DW
Dohnalkova
Alice C
AC
Mottaz
Heather M
HM
Hill
Eric A
EA
Gorby
Yuri A
YA
Beliaev
Alexander S
AS
Richardson
David J
DJ
Zachara
John M
JM
Fredrickson
James K
JK
D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D003580:Cytochromes / Q000378:metabolism*; D017353:Gene Deletion; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D020592:Shewanella / Q000235:genetics / Q000378:metabolism*
D001425:Bacterial Outer Membrane Proteins; D003580:Cytochromes; D026901:Membrane Transport Proteins