Crystal structures of the Mycobacterium tuberculosis secretory antigen alanine dehydrogenase (Rv2780) in apo and ternary complex forms captures "open" and "closed" enzyme conformations.
Tripathi
Sarvind Mani
SM
Molecular and Structural Biology Division, Central Drug Research Institute, Lucknow, India.
Ramachandran
Ravishankar
R
D050788:Alanine Dehydrogenase / Q000737:chemistry*; D000942:Antigens, Bacterial / Q000737:chemistry*; D001059:Apoproteins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D019281:Dimerization; D009169:Mycobacterium tuberculosis / Q000201:enzymology*; D009243:NAD / Q000378:metabolism; D020836:Protein Structure, Quaternary; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D019289:Pyruvic Acid / Q000378:metabolism
D000942:Antigens, Bacterial; D001059:Apoproteins; D009243:NAD; C072681:Mycobacterium tuberculosis antigens; D019289:Pyruvic Acid; D050788:Alanine Dehydrogenase