Extrapancreatic F-18 FDG accumulation in autoimmune pancreatitis.
We report two cases of autoimmune pancreatitis (AIP) in which fluorine-18 fluorodeoxyglucose (FDG) showed moderate accumulation in the pancreas, as well as in bilateral submandibular glands and in multifocal lymph nodes. FDG positron emission tomography (PET)/computed tomography (CT) is a useful diagnostic tool to assess the extrapancreatic lesions of AIP, which is a recently proposed new clinicopathological entity named immunoglobulin G4 (IgG4)-related systemic disease. Recognition of the FDG-PET/CT findings of IgG4-related sclerosing disease is crucial to avoid unnecessary surgery or other intervention because of similarities to malignant lymphoma or malignant tumor with multiple lymph node metastases.
Sato
Motohiro
M
Department of Radiology, Ibaraki Prefectural Central Hospital, 6528 Koibuchi, Kasama, Ibaraki, Japan. mo-sato@chubyoin.pref.ibaraki.jp
Okumura
Toshiyuki
T
Shioyama
Yasukazu
Y
Imura
Jyouji
J
D000368:Aged; D001327:Autoimmune Diseases; D049448:Cholangiopancreatography, Magnetic Resonance; D003937:Diagnosis, Differential; D005355:Fibrosis / Q000000981:diagnostic imaging; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D006801:Humans; D007074:Immunoglobulin G; D007150:Immunohistochemistry; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008297:Male; D009362:Neoplasm Metastasis; D010195:Pancreatitis / Q000000981:diagnostic imaging* / Q000473:pathology*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012468:Salivary Gland Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed
D007074:Immunoglobulin G; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18