title: 3-Tesla MRI for the evaluation of myocardial viability: a comparative study with 1.5-Tesla MRI.
abstract: OBJECTIVE
  We compared 3-Tesla (3-T) and 1.5-Tesla (1.5-T) cardiac magnetic resonance imaging (MRI) for the assessment of myocardial viability in nearly identical experimental conditions.
  
  
  METHODS
  Thirty-five patients (mean age 63+/-11; 94.2% men) submitted to primary coronary angioplasty underwent both 3-T and 1.5-T cardiac MRI, which was considered the gold standard. Comparison was performed on the basis of the same viability imaging protocol, which included resting cine-MR [balanced fast-field echo (B-FFE) sequence] followed by contrast-enhanced MR to evaluate perfusion and delayed enhancement (DE). We then performed functional index measurements and visual estimation of kinesis, perfusion and DE referring to a 5-point scale. Image quality was assessed on the basis of signal to noise ratio (SNR) and contrast to noise ratio (CNR).
  
  
  RESULTS
  We found nonsignificant differences between the two scanners (P=NS) in measuring the functional and viability parameters. Myocardial SNR was significantly higher with 3-T MRI compared with 1.5-T MRI (61.3% gain). Even though a loss of CNR was recorded in B-FFE and in first-pass perfusion sequences (12.4% and 23.7%, respectively), on DE images, we quantified the increase of SNR and CNR of infarction of 387.8% and 330%, respectively.
  
  
  CONCLUSIONS
  We found that 3-T MRI showed high concordance with 1.5-T MRI in the evaluation of functional and viability parameters and provided better evidence of damaged myocardium.
authors.affiliation: Cattedra e Servizio di Radiologia 1, Dipartimento di Servizi Diagnostici e per Immagine, Azienda Ospedaliero-Universitaria Policlinico di Modena, Università degli Studi di Modena e Reggio Emilia, Via del Pozzo 71, Modena, Italy. ligabue.guido@unimore.it
authors.forename: G
authors.initials: G
authors.lastname: Ligabue
authors.forename: F
authors.initials: F
authors.lastname: Fiocchi
authors.forename: S
authors.initials: S
authors.lastname: Ferraresi
authors.forename: A
authors.initials: A
authors.lastname: Barbieri
authors.forename: R
authors.initials: R
authors.lastname: Rossi
authors.forename: M G
authors.initials: MG
authors.lastname: Modena
authors.forename: R
authors.initials: R
authors.lastname: Romagnoli
authors.forename: P
authors.initials: P
authors.lastname: Torricelli
mesh_terms: D000368:Aged; D000465:Algorithms; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D003287:Contrast Media / Q000494:pharmacology; D003324:Coronary Artery Disease / Q000175:diagnosis; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009206:Myocardium / Q000473:pathology*; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D003287:Contrast Media