title: [Evaluation of a pilot intervention program for overweight and obese adults at risk of type 2 diabetes].
abstract: BACKGROUND
  The Ministry of Health of Chile and selected obesity specialized centers implemented an interdisciplinary pilot program for overweight adults at risk of diabetes to decrease the risk of type 2 diabetes (T2D) and cardiovascular risk factors (CVRF).
  
  
  OBJECTIVE
  To assess the results of this program.
  
  
  METHODS
  Beneficiaries of the public primary health system aged 18-45 years, with a body mass index (BMI) 25-38 kg/m(2) and fasting blood glucose 100-125 mg/dL or with any direct family member with T2D, were recruited. During the four months of the study, they were scheduled for three physician visits, four dietitian consultations, 14 physical activity sessions and four group workshops (two with a psychologist or therapist). In fasting blood samples, at the beginning and at the fourth month, glucose, insulin and lipids were determined. The Homeostasis model assessment (HOMA) index was calculated.
  
  
  RESULTS
  Two hundred-seventy-six patients were recruited and 160 (141 women), completed the four months of follow up. In this subgroup, at the start and end of the intervention, a BMI equal to or greater than 30 kg/m(2) was observed in 69% and 52% of subjects respectively, a systolic blood pressure equal to or greater than 140 mm Hg was observed in 24% and 6% respectively, a diastolic blood pressure equal to or greater than 90 mm Hg was observed in 28% and 9% respectively, a blood glucose equal to or greater than 100 mg/dL was observed in 61% and 19% respectively, a plasma insulin equal to or greater than 12,5 microUl/ml was observed in 49% and 34% respectively and a HOMA equal to or greater than 2.5 was observed in 63% and 42% respectively (all these comparisons are significant with a p <0.05).
  
  
  CONCLUSIONS
  In those patients that completed the follow up period, this intervention induced a significant decrease of some CVRF, such as BMI, fasting glucose levels and HOMA index.
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile. fcarrasc@med.uchile.cl
authors.forename: Fernando
authors.initials: F
authors.lastname: Carrasco
authors.forename: Manuel
authors.initials: M
authors.lastname: Moreno
authors.forename: Verónica
authors.initials: V
authors.lastname: Irribarra
authors.forename: Lorena
authors.initials: L
authors.lastname: Rodríguez
authors.forename: María Antonieta
authors.initials: MA
authors.lastname: Martin
authors.forename: Alejandra
authors.initials: A
authors.lastname: Alarcón
authors.forename: Claudio
authors.initials: C
authors.lastname: Mizón
authors.forename: Constanza
authors.initials: C
authors.lastname: Echenique
authors.forename: Víctor
authors.initials: V
authors.lastname: Saavedra
authors.forename: Tito
authors.initials: T
authors.lastname: Pizarra
authors.forename: Eduardo
authors.initials: E
authors.lastname: Atalah
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology; D002677:Chile / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control*; D004812:Epidemiologic Methods; D005260:Female; D006293:Health Promotion; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D010865:Pilot Projects; D015397:Program Evaluation; D011788:Quality of Life; D016312:Treatment Refusal