Longitudinal plane colour tissue-Doppler myocardial velocities and their association with left ventricular length, volume, and mass in humans.
OBJECTIVE
We investigated the relationships between colour tissue-Doppler parameters of left ventricular (LV) function and indices of LV morphology.


RESULTS
LV length, end-diastolic volume, and mass were assessed in 40 healthy adult subjects. Further, colour tissue-Doppler scans assessed peak myocardial velocities during systole (S') and early diastole (E') as well as acceleration during isovolumic contraction (IVCa) at the mitral annulus. Non-linear allometric relationships (Y = aX(b)) were calculated to provide size exponents (b), with 95% confidence intervals, for tissue-Doppler variables (Y) and LV morphology parameters (X). The b exponents for LV length with Peaks S' and E' were not substantially different from unity (b = 0.87 and 0.95, respectively, P > 0.05). Peak E' was also associated with LV volume (b = 0.39, r = 0.53, P < 0.05). IVCa was not related to any LV morphology parameter.


CONCLUSIONS
Peak S' or E' divided by LV length was confirmed as a valid size-independent scaling index. Conversely, IVCa is seemingly size independent.
Batterham
Alan
A
Centre for Food, Physical Activity, and Obesity Research, University of Teesside, Middlesbrough, UK.
Shave
Rob
R
Oxborough
David
D
Whyte
Greg
G
George
Keith
K
D000328:Adult; D018618:Echocardiography, Doppler, Color; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009929:Organ Size; D016277:Ventricular Function, Left / Q000502:physiology*