title: Transmission of infectious bronchitis virus within vaccinated and unvaccinated groups of chickens.
abstract: The aim of this study was to determine whether vaccination against infectious bronchitis virus (IBV) reduces virus transmission, i.e. to test whether IBV transmission among vaccinated chickens is significantly reduced compared to that among unvaccinated chickens. In two vaccinated and two unvaccinated groups of SPF chickens, a standard measure for virus transmission, the reproduction ratio (R) was determined. R is defined as the average number of new infections caused by one typical infectious individual during its entire infectious period. A single vaccination by eye-drop with IBV H120 reduced the transmission of the IBV challenge virus among the vaccinated chickens (estimated R = 0.69, s.e. = 0.33) significantly (P < 0.05) compared to the transmission among the unvaccinated chickens (estimated R = 19.95, s.e. = 12.41). The possible implications for further study, including selection or development of vaccines are discussed.
authors.affiliation: Animal Health Service, Deventer.
authors.forename: J J
authors.initials: JJ
authors.lastname: de Wit
authors.forename: M C
authors.initials: MC
authors.lastname: de Jong
authors.forename: A
authors.initials: A
authors.lastname: Pijpers
authors.forename: J H
authors.initials: JH
authors.lastname: Verheijden