title: Scleroderma: oral manifestations and treatment challenges.
abstract: Scleroderma is a connective tissue disorder of excess collagen production characterized by intense fibrosis of the skin, with internal organ involvement. A wide range of oral sequelae-including microstomia, oral mucosal/gingival fibrosis, xerostomia, and mandibular bone resorption-complicates maintenance of oral health and dental treatment. The literature is reviewed, and two cases are presented.
authors.affiliation: Department of Dentistry, UNC Hospitals, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7450, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Fischer
authors.forename: L L
authors.initials: LL
authors.lastname: Patton
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000209:etiology; D001284:Atrophy; D003731:Dental Caries / Q000209:etiology; D005260:Female; D005889:Gingival Recession / Q000209:etiology; D006801:Humans; D008297:Male; D008334:Mandible / Q000473:pathology; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000150:complications*; D013705:Temporomandibular Joint Disorders / Q000209:etiology; D014987:Xerostomia / Q000209:etiology