title: Monte Carlo calculations and experimental measurements of dosimetric parameters of the IRA-103Pd brachytherapy source.
abstract: This article presents a brachytherapy source having 103Pd adsorbed onto a cylindrical silver rod that has been developed by the Agricultural, Medical, and Industrial Research School for permanent implant applications. Dosimetric characteristics (radial dose function, anisotropy function, and anisotropy factor) of this source were experimentally and theoretically determined in terms of the updated AAPM Task group 43 (TG-43U1) recommendations. Monte Carlo simulations were used to calculate the dose rate constant. Measurements were performed using TLD-GR200A circular chip dosimeters using standard methods employing thermoluminescent dosimeters in a Perspex phantom. Precision machined bores in the phantom located the dosimeters and the source in a reproducible fixed geometry, providing for transverse-axis and angular dose profiles over a range of distances from 0.5 to 5 cm. The Monte Carlo N-particle (MCNP) code, version 4C simulation techniques have been used to evaluate the dose-rate distributions around this model 103Pd source in water and Perspex phantoms. The Monte Carlo calculated dose rate constant of the IRA-103Pd source in water was found to be 0.678 cGy h(-1) U(-1) with an approximate uncertainty of +/-0.1%. The anisotropy function, F(r, theta), and the radial dose function, g(r), of the IRA- 103Pd source were also measured in a Perspex phantom and calculated in both Perspex and liquid water phantoms.
authors.affiliation: Nuclear Medicine Research Group, Agricultural, Medical & Industrial Research School, Karaj, Iran. msadeghi@nrcam.org
authors.forename: Mahdi
authors.initials: M
authors.lastname: Sadeghi
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Raisali
authors.forename: S Hamed
authors.initials: SH
authors.lastname: Hosseini
authors.forename: Arzhang
authors.initials: A
authors.lastname: Shavar
mesh_terms: D001822:Body Burden; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008954:Models, Biological; D009010:Monte Carlo Method; D010165:Palladium / Q000032:analysis* / Q000627:therapeutic use*; D019736:Prostheses and Implants; D011868:Radioisotopes / Q000032:analysis / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness; D012542:Scattering, Radiation
chemical_list: D011868:Radioisotopes; D010165:Palladium