Homogeneous and label-free bioluminescence detection of single nucleotide polymorphism with rolling circle amplification.
Integration of rolling circle amplification and sensitive bioluminescent detection of pyrophosphate, a homogeneous and label-free method has been developed for detecting single nucleotide polymorphism.
Cheng
Yongqiang
Y
College of Chemistry and Environment Science, Hebei University, Baoding, 071002, Hebei Province, P. R. China. lzpbd@mail.hbu.edu.cn.
Li
Zhengping
Z
Du
Baoan
B
Zhang
Xian
X
D000818:Animals; D011756:Diphosphates / Q000032:analysis; D006801:Humans; D008164:Luminescent Proteins; D021141:Nucleic Acid Amplification Techniques; D015345:Oligonucleotide Probes; D020641:Polymorphism, Single Nucleotide; D012680:Sensitivity and Specificity
D011756:Diphosphates; D008164:Luminescent Proteins; D015345:Oligonucleotide Probes