title: Voluntary cough production and swallow dysfunction in Parkinson's disease.
abstract: Cough is important for airway clearance, particularly if penetration/aspiration of foreign material occurs during swallow. Measures of voluntary cough production from ten male participants with stage II-III Parkinson's disease (PD) who showed no videofluorographic evidence of penetration/aspiration (Group 1) were examined and compared with those of ten male participants with stage II-III PD who showed videofluorographic evidence of penetration/aspiration (Group 2). The degree of penetration/aspiration was expertly judged from the videofluorographic examinations of the participants' sequential swallow of a thin, 30-cc bolus. Measured cough parameters included inspiratory phase duration, inspiratory peak flow, compression phase duration, expiratory peak flow, expiratory rise time, and cough volume acceleration. Results indicated significant group differences for the majority of cough measures, except for inspiratory phase duration and inspiratory peak flow. A modest relationship existed between voluntary cough parameters and penetration/aspiration scores. Decreased ability to adequately clear material from the airway with voluntary cough may exacerbate symptoms resulting from penetration/aspiration, particularly for those with neurodegenerative disease. Measurement of voluntary cough may be useful for the evaluation of airway clearance ability.
authors.affiliation: Department of Communication Sciences and Disorders, University of Florida, Gainesville, Florida 32610, USA. tepitts@gmail.com
authors.forename: Teresa
authors.initials: T
authors.lastname: Pitts
authors.forename: Donald
authors.initials: D
authors.lastname: Bolser
authors.forename: John
authors.initials: J
authors.lastname: Rosenbek
authors.forename: Michelle
authors.initials: M
authors.lastname: Troche
authors.forename: Christine
authors.initials: C
authors.lastname: Sapienza
mesh_terms: D000368:Aged; D003371:Cough; D003679:Deglutition; D003680:Deglutition Disorders / Q000209:etiology / Q000503:physiopathology*; D005471:Fluoroscopy / Q000295:instrumentation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology*; D010366:Peak Expiratory Flow Rate; D015203:Reproducibility of Results; D012119:Respiration