Cytokinesis: the final stop for the chromosomal passengers.
The CPC (chromosomal passenger complex) performs essential roles in the regulation and co-ordination of chromosomal and cytoskeletal events during mitosis and meiosis. The first functional analyses showed evidence of a role of the CPC in the regulation of cytokinesis. In this review, I summarize what we have learned since then about the role of the CPC in the late stages of mitosis and cytokinesis.
Carmena
Mar
M
Wellcome Trust Centre for Cell Biology, School of Biological Sciences. University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR, UK. mar.carmena@ed.ac.uk
D000205:Actomyosin / Q000378:metabolism; D000818:Animals; D002875:Chromosomes / Q000378:metabolism*; D048749:Cytokinesis; D003598:Cytoskeletal Proteins / Q000378:metabolism; D006801:Humans; D007382:Intermediate Filaments / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism
D003598:Cytoskeletal Proteins; D000205:Actomyosin