title: Gastric involvement of extranodal NK/T-cell lymphoma, nasal type: a report of 3 cases with literature review.
abstract: Gastric involvement of extranodal natural killer/T-cell lymphoma, nasal type is extremely rare, and its clinicopathologic features are also poorly understood. Until now, only 4 cases have been reported in literature. In this article, 3 cases of extranodal natural killer/T-cell lymphoma, nasal type are reported. In this current series, one patient (case 2) was admitted to emergency due to life-threatened hemorrhage of the upper-digestive tract and the volume of blood loss was about 2000 mL. For case 3, the sample was a small piece of gastroendoscopy biopsy tissue. It is a challenge for pathologist to make the diagnosis for this special type of tumor. In all, 2 of 3 cases had a relevant history of midfacial extranodal natural killer/T-cell lymphoma, nasal type before. The other patient died of tumor 2 months later with no history of the tumor when she was alive. Literature review was carried out; The cases reported in this article are documented and compared with the 4 previously reported cases of tumor.
authors.affiliation: Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Zhang
authors.lastname: Sha Zhao
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Yu
authors.lastname: Lei Shi
authors.forename: Miao-Xia
authors.initials: MX
authors.lastname: He
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Zhang
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Liu
mesh_terms: D000328:Adult; D020031:Epstein-Barr Virus Infections / Q000150:complications; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D054391:Lymphoma, Extranodal NK-T-Cell / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D013274:Stomach Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy