Pseudoaneurysm of the peroneal artery: presentation of Ehlers-Danlos syndrome type IV.
BACKGROUND
Pseudoaneurysms in deep or unusual sites raise the possibility of an underlying vessel wall disorder.


METHODS
A 28-year-old woman presented with pain and swelling of her calf, with no history of trauma. Angiography diagnosed a peroneal artery pseudoaneurysm, which we embolised successfully. Subsequent genetic analysis revealed the COL3A1 mutation, confirming Ehlers-Danlos syndrome type IV.


CONCLUSIONS
To our knowledge, this is the first report of a peroneal artery pseudoaneurysm associated with underlying collagen vascular disease.
Mandeville
K
K
St Mary's Hospital, South Wharf Road, Paddington, London W2 1NY, United Kingdom. kate.mandeville@imperial.ac.uk
Bicknell
C
C
Tran
T
T
MacDermot
K
K
Renton
S
S
D000328:Adult; D017541:Aneurysm, False / Q000209:etiology* / Q000628:therapy; D024061:Collagen Type III / Q000235:genetics; D004535:Ehlers-Danlos Syndrome / Q000150:complications* / Q000235:genetics; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans
C439971:COL3A1 protein, human; D024061:Collagen Type III