title: Obstetric and perinatal outcome in 200 infants conceived from vitrified oocytes.
abstract: Cryopreservation of oocytes by vitrification is a promising new technique for assisted human reproduction. Any new technical development must be accompanied with data concerning obstetric and perinatal outcome. This study analysed the obstetric and perinatal outcomes in 165 pregnancies and 200 infants conceived following oocyte vitrification cycles in three assisted reproduction centres. The results indicate that the mean birth weight and the incidence of congenital anomalies are comparable to that of spontaneous conceptions in fertile women or infertile women undergoing in-vitro fertilization treatment. These preliminary findings may provide reassuring evidence that pregnancies and infants conceived following oocyte vitrification are not associated with increased risk of adverse obstetric and perinatal outcomes.
authors.affiliation: McGill Reproductive Center, Department of Obstetrics and Gynecology, McGill University, Montreal, Canada. ri-cheng.chian@muhc.mcgill.ca
authors.forename: Ri-Cheng
authors.initials: RC
authors.lastname: Chian
authors.forename: Jack Y J
authors.initials: JY
authors.lastname: Huang
authors.forename: Seang Lin
authors.initials: SL
authors.lastname: Tan
authors.forename: Elkin
authors.initials: E
authors.lastname: Lucena
authors.forename: Angela
authors.initials: A
authors.lastname: Saa
authors.forename: Alejandro
authors.initials: A
authors.lastname: Rojas
authors.forename: Luis Arturo
authors.initials: LA
authors.lastname: Ruvalcaba Castellón
authors.forename: Martha Isolina
authors.initials: MI
authors.lastname: García Amador
authors.forename: Jorge Eduardo
authors.initials: JE
authors.lastname: Montoya Sarmiento
mesh_terms: D000328:Adult; D001724:Birth Weight; D000013:Congenital Abnormalities; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D009865:Oocytes; D011247:Pregnancy; D011256:Pregnancy Outcome