title: The relationship between effective arterial capacitance and pulse wave velocity is dependent on left ventricular stroke volume.
abstract: BACKGROUND
  increased arterial stiffness is a predictor of cardiovascular events. The stroke volume (SV) to pulse pressure (PP) ratio is an estimate of arterial capacitance. Pulse wave velocity (PWV) is a measure of arterial stiffness. This study evaluated the effect of left ventricular (LV) SV on the SV/PP-PWV relationship.
  
  
  METHODS
  97 patients had applanation tonometry and echocardiography to measure arterial capacitance (SV/PP), PWV, and central aortic pressure.
  
  
  RESULTS
  50 patients had normal SV and 47 had low SV. For all patients, PWV inversely correlated with SV/PP. PWV and SV/PP correlated more strongly in the normal SV group than in the low SV group. Aortic PP was significantly correlated with PWV in all patients, in the normal SV group, and in the low SV group.
  
  
  CONCLUSIONS
  effective arterial capacitance correlates with PWV. The presence of decreased SV weakens the relationship.
authors.affiliation: Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, USA.
authors.forename: Oladipupo
authors.initials: O
authors.lastname: Olafiranye
authors.forename: Ghazanfar
authors.initials: G
authors.lastname: Qureshi
authors.forename: Louis
authors.initials: L
authors.lastname: Salciccioli
authors.forename: Kinda
authors.initials: K
authors.lastname: Vernon-Jones
authors.forename: Charles
authors.initials: C
authors.lastname: Philip
authors.forename: John
authors.initials: J
authors.lastname: Kassotis
authors.forename: Jason M
authors.initials: JM
authors.lastname: Lazar
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000503:physiopathology*; D001794:Blood Pressure; D001916:Brachial Artery / Q000503:physiopathology*; D004548:Elasticity; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D008955:Models, Cardiovascular; D012189:Retrospective Studies; D019722:Sphygmomanometers; D013318:Stroke Volume; D014463:Ultrasonography; D018924:Vascular Capacitance; D016277:Ventricular Function, Left