Alterations of aqueous flare and cells detected by laser flare-cell photometry in patients with Behcet's disease.
OBJECTIVE
To quantitatively evaluate aqueous flare and cells in patients with Behcet's disease.


METHODS
This study included 30 Behcet's patients (52 eyes) with active uveitis. The patients were treated with immunosuppressive agents. Aqueous flare and cells were quantified using the laser flare-cell photometry before treatment and 1 and 2 months after treatment.


RESULTS
Before treatment, mean aqueous flare (ph/ms) in Behcet's eyes was 25.7 ± 20.5. After treatment, flare values were significantly reduced after 1 and 2 months compared with those before treatment. No significant difference was found between flare values after 1 and 2 months. Before treatment, mean cell counts (cells/0.5 mm(3)) in Behcet's eyes were 23.2 ± 29.4. After treatment, cell counts were also significantly reduced after 1 and 2 months compared with those before treatment. Cell counts were further significantly reduced from 1 to 2 months.


CONCLUSIONS
Both aqueous flare and cells were significantly increased in Behcet's patients with active uveitis and improved after a two-month treatment. Breakdown of the blood-aqueous barrier lasts longer than aqueous cells in these patients.
Yang
Peizeng
P
State Key Laboratory of Ophthalmology of Sun Yat-sen University, Guangzhou, Peoples Republic of China. peizengyang@hotmail.com
Fang
Wang
W
Huang
Xiangkun
X
Zhou
Hongyan
H
Wang
Li
L
Jiang
Bo
B
D000293:Adolescent; D000328:Adult; D001082:Aqueous Humor / Q000166:cytology*; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D018916:Blood-Aqueous Barrier; D002452:Cell Count; D005260:Female; D006801:Humans; D007834:Lasers; D008297:Male; D010783:Photometry; D014605:Uveitis / Q000175:diagnosis*; D055815:Young Adult