title: Antifungal activity of solventlessly synthesized organomercurials.
abstract: A series of new barbituryl/thiobarbituryl substituted organomercurial derivatives 3a-i have been synthesised from pyrimidine derivatives 1a-c and arylmercuric chloride 2a-c over K(2)CO(3) under microwave irradiations (MWI). This solventless synthesis apart from eliminating organic solvent from workup step, also gave improved yield as compared to the conventional heating, with reaction time reduced from hours to minutes. The prepared compounds were tested against A. niger and A. flavous for their antifungal activity and were found to posses good activity.
authors.affiliation: Department of Chemistry University of Delhi Delhi 110007 India.
authors.forename: M
authors.initials: M
authors.lastname: Kidwai
authors.forename: R
authors.initials: R
authors.lastname: Venkataramanan
authors.forename: B
authors.initials: B
authors.lastname: Dave