title: Cerebral arteries: fully automated segmentation from CT angiography--a feasibility study.
abstract: The purpose of this study was to retrospectively assess the feasibility of a fully automated image postprocessing tool for the segmentation of the arterial cerebrovasculature from computed tomographic (CT) angiography in 27 patients (nine men, 18 women; mean age, 55 years; age range, 33-76 years) with subarachnoid hemorrhage. The institutional review board approved this study, and informed consent was waived. The proposed method, which does not require the acquisition of an additional CT scan for bone suppression, consists of the following: (a) automatic detection of the main arteries for initialization, (b) segmentation of these arteries through the skull base, and (c) suppression of the large veins near the skull. The parameters of this method were optimized on the training subset of nine patients, and the method was successful at segmentation of the arteries in 15 (83%) of the 18 remaining patients. The difference between automatic and manual diameter measurements was 0.0 mm +/- 0.4 (standard deviation). The study results showed that fully automated segmentation of the cerebral arteries is feasible.
authors.affiliation: Departments of Medical Informatics and Radiology, Erasmus MC-University Medical Center Rotterdam, Dr. Molewaterplein 40/50, 3015 GE Rotterdam, the Netherlands. r.manniesing@erasmusmc.nl
authors.forename: Rashindra
authors.initials: R
authors.lastname: Manniesing
authors.forename: Max A
authors.initials: MA
authors.lastname: Viergever
authors.forename: Aad
authors.initials: A
authors.lastname: van der Lugt
authors.forename: Wiro J
authors.initials: WJ
authors.lastname: Niessen
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D001331:Automation; D002533:Cerebral Angiography / Q000379:methods*; D002536:Cerebral Arteries; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide