A facile route to 2,4-dihydro-1H-benzo[d][1,3]thiazines via silver-catalyzed tandem addition-cyclization reactions.
Tandem addition-cyclization reactions of 2-alkynylbenzenamines with isothiocyanates catalyzed by silver triflate are described; they provide an efficient and practical route for the synthesis of 2,4-dihydro-1 H-benzo[ d][1,3]thiazines.
Ding
Qiuping
Q
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China.
Wu
Jie
J
D000478:Alkylation; D001550:Benzamidines / Q000737:chemistry; D001554:Benzene / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D017953:Isocyanates / Q000737:chemistry; D015394:Molecular Structure; D012834:Silver / Q000737:chemistry*; D013843:Thiazines / Q000737:chemistry*
D001550:Benzamidines; D005663:Furans; D017953:Isocyanates; D013843:Thiazines; D012834:Silver; D006859:Hydrogen; D001554:Benzene; C032157:benzamidine