Analysis of bone marrow from patients in critical condition.
The aim of the research was to determine the composition of nitrous oxide and free peroxide-radicals in bone marrow in critical condition. 27 adult patients (20 male and 7 female) in critical condition of various geneses (sepsis, insult, trauma etc.) were examined. All patients were under artificial ventilation of lungs. Morphological study of bone marrow was conducted. The research revealed toxic grains in some bone marrow punctates in critical condition. The neutrophil myelocytes were in norm (8.4+/-1.1). The quantity of metamyelocytes were increased (7.1+/-0.5-N7.7+/-0.7, P>0.5). The quantity of the mature neutrophil with a segmented nucleus were increased (34.7+/-1.4-N-36.4+/-2.1, P>0.5). The quantity of neutrophil nucleus bacillus increased (12.6+/-0.5-N -13.5+/-0.7, P>0.5). The quantity of neutrophilic promyelocyte was in norm (0.96+/-0.1-N-1.4+/-0.2, P>0.1). The quantity of lymphocytes is increased (9.0+/-0.6-N-10+/-0.7, P>0.5). The quantity of monocytes is unchanged (1.3+/-0.1- N-1.3+/-0.2, P>0.5). Basophilic normoblasts are increased in patients with critical conditions (2.0+/-0.4-N-2.1+/-0.5, P>0.5). Policromathohilic normoblasts are significantly decreased. (4.6+/-0.96-N- 2.1+/-0.6, P>0.005) The quantity of oxyphilic normoblasts is increased (6.9+/-0.7-N-9.0+/-0.4, P>0.5). Plasma cells (0.8+/-0.1-N-1.0+/-0.1) and blastic cells (0.6+/-0.04 - N-0.5+/-0.1) are in norm.
Palavandishvili
A
A
Kheladze
Z
Z
Sanikidze
T
T
Chubinidze
N
N
Kheladze
Z
Z
D001853:Bone Marrow / Q000737:chemistry* / Q000473:pathology*; D016638:Critical Illness; D005260:Female; D006801:Humans; D008297:Male; D009609:Nitrous Oxide / Q000032:analysis; D010545:Peroxides / Q000032:analysis
D010545:Peroxides; D009609:Nitrous Oxide