Acute myelomonocytic leukaemia with short-term spontaneous remission in a cat.
A 2-year-old, spayed female domestic shorthair cat was referred with a history of anorexia and depression of 1 week duration. On physical examination, the cat was lethargic and febrile, with splenomegaly, anisocoria and ulcerative stomatitis. A complete blood count (CBC) and a biochemistry profile showed leukocytosis, numerous blast cells in the peripheral blood, thrombocytopenia, hyperglobulinaemia and a positive test for feline leukaemia virus antigen. A diagnosis of acute myelomonocytic leukaemia was made on the basis of the results of bone marrow cytology, histopathology, and immunochemistry (CD3, CD79a, lysozyme, and myeloperoxidase) tests. Following an unexpected 1-month period of clinical and clinicopathological remission without chemotherapy, the cat relapsed and died 1 week later.
Mylonakis
M E
ME
Companion Animal Clinic, Aristotle University of Thessaloniki, Greece. mmylonak@vet.auth.gr
Petanides
T A
TA
Valli
V E
VE
Vernau
W
W
Koytinas
A F
AF
Michael
R S
RS
D000818:Animals; D000855:Anorexia / Q000209:etiology / Q000662:veterinary; D001772:Blood Cell Count / Q000662:veterinary; D001854:Bone Marrow Cells / Q000473:pathology; D002371:Cat Diseases / Q000175:diagnosis* / Q000473:pathology; D002415:Cats; D017809:Fatal Outcome; D005260:Female; D015479:Leukemia, Myelomonocytic, Acute / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D009365:Neoplasm Regression, Spontaneous; D015431:Weight Loss