[Sinonasal adenocarcinomas: our experience].
OBJECTIVE
Sinonasal adenocarcinoma is a rare epithelial cancer of the nasal cavities and paranasal sinuses and exposure to sawdust particles is a strong aetiological factor.


METHODS
Seventy-nine patients (78 men and 1 woman) operated on between 1986 and 2002 were studied.


RESULTS
In 62 patients (78.5 %) there was a history of exposure to wood dust. The clinical factors presenting statistical significance in the multivariate analysis with prognosis were: the exclusive invasion of the middle concha (as good prognosis), recurrence and invasion of the dura mater (as bad prognosis). The actuarial survival rate was 36 % at 5 years falling to 28 % at 10 years.


CONCLUSIONS
Exposure to wood dust, even over a short period of time, must be considered as a high risk factor for the development of a sinonasal adenocarcinoma. This tumour must be ruled out in all patients suffering any type of sinonasal pathology.
Llorente
José Luis
JL
Servicio de Otorrinolaringología y Unidad de Base de Cráneo, Instituto Universitario de Oncología del Principado de Asturias, Hospital Central Universitario de Asturias, Oviedo, Asturias, España. llorentependas@telefonica.net
Núñez
Faustino
F
Rodrigo
Juan Pablo
JP
Fernández León
Ramón
R
Alvarez
César
C
Hermsen
Mario
M
Suárez
Carlos
C
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004391:Dust; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D012307:Risk Factors; D014934:Wood
D004391:Dust