title: Surface coatings for improvement of bone cell materials and antimicrobial activities of Ti implants.
abstract: Ti surface was modified to simultaneously improve bone cell materials and antimicrobial activities. Titanium surface was first anodized in sodium fluoride and sulfuric acid electrolytic solution to form titania nanotube on the surface to improve the biocompatibility of the surface. Silver was electrodeposited on the titania nanotube surface at 5 V. Silver added titania nanotube surface was tested for compatibility with bone-cell materials interactions using human osteoblast bone cells. The antibacterial effect was studied using Pseudomonas aeruginosa. Our results show that silver-treated titania nanotube surface may provide antibacterial properties to prevent implants against postoperative infections without interference to the attachment and proliferation of bone tissue on titanium, which is commonly used in dental and orthopedic surgical procedures.
authors.affiliation: W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, USA.
authors.forename: Kakoli
authors.initials: K
authors.lastname: Das
authors.forename: Susmita
authors.initials: S
authors.lastname: Bose
authors.forename: Amit
authors.initials: A
authors.lastname: Bandyopadhyay
authors.forename: Balu
authors.initials: B
authors.lastname: Karandikar
authors.forename: Bruce L
authors.initials: BL
authors.lastname: Gibbins
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D008855:Microscopy, Electron, Scanning; D043942:Nanotubes / Q000737:chemistry / Q000648:ultrastructure; D010006:Osteoblasts / Q000166:cytology / Q000187:drug effects; D019736:Prostheses and Implants; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012834:Silver / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D014025:Titanium