title: Identification of new quantitative trait Loci (other than the PRNP gene) modulating the scrapie incubation period in sheep.
abstract: Although susceptibility to scrapie is largely controlled by the PRNP gene, we have searched for additional genomic regions that affect scrapie incubation time in sheep, using two half-sib families with a susceptible PRNP genotype and naturally infected by scrapie. Quantitative trait loci were detected on OAR6 and OAR18.
authors.affiliation: INRA, UR 631 Amélioration Génétique des Animaux, BP52627, 31326 Castanet-Tolosan, France. moreno@toulouse.inra.fr
authors.forename: C R
authors.initials: CR
authors.lastname: Moreno
authors.forename: G M
authors.initials: GM
authors.lastname: Cosseddu
authors.forename: L
authors.initials: L
authors.lastname: Schibler
authors.forename: A
authors.initials: A
authors.lastname: Roig
authors.forename: K
authors.initials: K
authors.lastname: Moazami-Goudarzi
authors.forename: O
authors.initials: O
authors.lastname: Andreoletti
authors.forename: F
authors.initials: F
authors.lastname: Eychenne
authors.forename: D
authors.initials: D
authors.lastname: Lajous
authors.forename: F
authors.initials: F
authors.lastname: Schelcher
authors.forename: E P
authors.initials: EP
authors.lastname: Cribiu
authors.forename: P
authors.initials: P
authors.lastname: Laurent
authors.forename: D
authors.initials: D
authors.lastname: Vaiman
authors.forename: J M
authors.initials: JM
authors.lastname: Elsen
mesh_terms: D000818:Animals; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D007113:Immunity, Innate / Q000235:genetics*; D016013:Likelihood Functions; D040641:Quantitative Trait Loci / Q000235:genetics*; D012608:Scrapie / Q000235:genetics*; D012756:Sheep; D016019:Survival Analysis; D013997:Time Factors