title: Aqueous solubility and Daphnia magna chronic toxicity of di(2-ethylhexyl) adipate.
abstract: A water solubility of 5.5 (+/-0.22) microg/L for di(2-ethylhexyl) adipate (DEHA) was measured using the slow-stir method. This value is consistent with computer estimations and over two orders of magnitude lower than that previously determined using the shake-flask method. We performed a 21-day chronic Daphnia magna limit test at an average exposure of 4.4 microg/L in laboratory diluent water to avoid insoluble test material and avoid physical entrapment. One hundred percent of the DEHA-treated organisms survived compared to 90% survival in both the controls and solvent controls. Mean neonate reproduction was 152, 137, and 148 and mean dry weight per surviving female was 0.804, 0.779, and 0.742 mg in the DEHA treatment, control, and solvent control, respectively. No adverse effects were observed.
authors.affiliation: Department of Chemistry, Rochester Institute of Technology, Rochester, NY 14623, USA. krobilla@rochester.rr.com
authors.forename: K A
authors.initials: KA
authors.lastname: Robillard
authors.forename: D L
authors.initials: DL
authors.lastname: Dufresne
authors.forename: J W
authors.initials: JW
authors.lastname: Gorsuch
authors.forename: W A
authors.initials: WA
authors.lastname: Stubblefield
authors.forename: C A
authors.initials: CA
authors.lastname: Staples
authors.forename: T F
authors.initials: TF
authors.lastname: Parkerton
mesh_terms: D000272:Adipates / Q000737:chemistry / Q000633:toxicity*; D000818:Animals; D003621:Daphnia; D007814:Larva / Q000187:drug effects; D008136:Longevity / Q000187:drug effects; D010968:Plasticizers / Q000737:chemistry / Q000633:toxicity*; D012098:Reproduction / Q000187:drug effects; D012995:Solubility; D018675:Toxicity Tests; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D000272:Adipates; D010968:Plasticizers; D014874:Water Pollutants, Chemical; D014867:Water; C013966:dioctyl adipate