A metal-mediated conformational switch controls G-quadruplex binding affinity.
Monchaud
David
D
Institut Curie, Section Recherche, CNRS, UMR176, Centre Universitaire Paris XI, Bâtiment 110, 91405 Orsay, France.
Yang
Peng
P
Lacroix
Laurent
L
Teulade-Fichou
Marie-Paule
MP
Mergny
Jean-Louis
JL
D002942:Circular Dichroism; D003300:Copper / Q000737:chemistry*; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D054856:G-Quadruplexes; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D009691:Nucleic Acid Denaturation; D011725:Pyridines / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
C502660:2,6-N,N'-methyl-quinolinio-3-yl-pyridine dicarboxamide; D008024:Ligands; D011725:Pyridines; D011804:Quinolines; D003300:Copper; D004247:DNA