title: Acute appendicitis--a benign disease?
abstract: BACKGROUND
  Appendicitis is the most common cause of the acute abdomen and can affect all age groups. Most patients recover quickly but a minority can suffer postoperative complications. This case-note review was undertaken to assess the frequency of these complications.
  
  
  METHODS
  Adult patients (> 16 years) undergoing an emergency appendicectomy at a University teaching hospital between February 2004 and January 2005 were identified from pathology records. Details of operative procedure, histology and postoperative complications were noted from the hospital case notes
  
  
  RESULTS
  A total of 199 patients with a median age of 31 years (range, 16-89 years) were identified. Of these, 58 (29%) patients experienced a postoperative complication. Eight (4%) patients were admitted to the surgical high dependency unit or intensive care unit postoperatively and there was one death (0.5%). Re-operation for a postoperative complication was required in 9 (4.5%) patients and there was a 13% re-admission rate (26 patients). Comparison between patients with histologically proven appendicitis (164 patients; 82%) and those patients having a negative appendicectomy (35 patients; 18%) showed no significant difference in the rate of complications as defined (43 of 164, 26% versus 15 of 35, 43%; P = 0.08). However, patients with positive histology were more likely to experience a septic complication (29 of 164, 18% versus 1 of 35, 3%; P = 0.028) and all re-operations came from this group. Despite this, patients with a negative appendicectomy were more likely to be re-admitted (12 of 35, 34% versus 14 of 164, 8.5%; P = 0.0002), predominantly with persistent abdominal pain.
  
  
  CONCLUSIONS
  Appendicectomy is associated with a significant morbidity. Patients with an inflamed appendix were more likely to experience a septic complication but re-admission was more common in patients with a histologically normal appendix because of unresolved abdominal pain.
authors.affiliation: Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, UK. j.simpson@nottingham.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Simpson
authors.forename: A Pr
authors.initials: AP
authors.lastname: Samaraweera
authors.forename: R K
authors.initials: RK
authors.lastname: Sara
authors.forename: D N
authors.initials: DN
authors.lastname: Lobo
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001062:Appendectomy / Q000379:methods*; D001064:Appendicitis / Q000601:surgery*; D003422:Critical Care / Q000706:statistics & numerical data; D004630:Emergencies; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery; D011300:Preoperative Care / Q000379:methods; D012086:Reoperation / Q000706:statistics & numerical data; D016896:Treatment Outcome