Metabolites from the endophytic fungus Xylaria sp. PSU-D14.
Glucoside derivatives, xylarosides A (1) and B (2), were isolated from the broth extract of the endophytic fungus Xylaria sp. PSU-D14 along with two known compounds, sordaricin (3) and 2,3-dihydro-5-hydroxy-2-methyl-4H-1-benzopyran-4-one (4). The structures were assigned by spectroscopic methods. Sordaricin (3), one of the known metabolites, exhibited moderate antifungal activity against Candida albicans ATCC90028 with a MIC value of 32 microg/ml.
Pongcharoen
Wipapan
W
Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand.
Rukachaisirikul
Vatcharin
V
Phongpaichit
Souwalak
S
Kühn
Till
T
Pelzing
Matthias
M
Sakayaroj
Jariya
J
Taylor
Walter C
WC
D005960:Glucosides / Q000737:chemistry / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013098:Xylariales / Q000737:chemistry / Q000145:classification / Q000378:metabolism*
D005960:Glucosides