title: Tramadol and strong opioid: synergistic or additive opioid effect?
authors.forename: Luigi
authors.initials: L
authors.lastname: Di Lorenzo
mesh_terms: D000279:Administration, Cutaneous; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002908:Chronic Disease; D003953:Diagnosis-Related Groups; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D009020:Morphine / Q000008:administration & dosage / Q000627:therapeutic use; D009369:Neoplasms / Q000503:physiopathology; D009437:Neuralgia / Q000188:drug therapy; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D014147:Tramadol / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D014147:Tramadol; D009020:Morphine; D005283:Fentanyl