title: bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia.
abstract: The IMP-4 metallo-beta-lactamase, originally recognized in Acinetobacter spp. from Hong Kong, more recently appeared simultaneously in isolates of the family Enterobacteriaceae from Sydney and Melbourne, Australia. The bla(IMP-4)-qacG2-aacA4-catB3 cassette array was found in isolates from both cities, but in different wider genetic contexts and on different plasmids, suggesting movement of this array by homologous recombination.
authors.affiliation: Centre for Infectious Diseases & Microbiology, University of Sydney, Westmead Hospital, Westmead, New South Wales 2145, Australia.
authors.forename: Björn A
authors.initials: BA
authors.lastname: Espedido
authors.forename: Sally R
authors.initials: SR
authors.lastname: Partridge
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Iredell
mesh_terms: D001315:Australia; D001426:Bacterial Proteins / Q000235:genetics*; D004755:Enterobacteriaceae / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; C425142:beta-lactamase IMP-4; D001618:beta-Lactamases