Porin new light onto chromatin and nuclear organization.
A recent report identifies sites in the human genome that can associate with nucleoporin 93, a subunit of the nuclear pore complex. These associations are modulated by levels of global histone acetylation and highlight the dynamic nature of chromatin organization in the nucleus.
Finlan
Lee E
LE
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, UK. lfinlan@hgu.mrc.ac.uk
Bickmore
Wendy A
WA
D002467:Cell Nucleus / Q000737:chemistry*; D002843:Chromatin / Q000737:chemistry*; D006655:Histone Deacetylases / Q000378:metabolism; D006801:Humans; D028861:Nuclear Pore Complex Proteins / Q000378:metabolism; D018272:Porins / Q000378:metabolism*
D002843:Chromatin; D028861:Nuclear Pore Complex Proteins; D018272:Porins; D006655:Histone Deacetylases