B young again.
Hanna et al. (2008) report in a recent issue of Cell that a defined set of transcription factors can reprogram mature B cells back to pluripotent stem cells.
Graf
Thomas
T
Center for Genomic Regulation, Carrer Dr. Aiguader 88, E-08003 Barcelona, Spain. thomas.graf@crg.es
Busslinger
Meinrad
M
D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D002454:Cell Differentiation / Q000235:genetics; D002460:Cell Line; D065150:Cellular Reprogramming; D002678:Chimera / Q000235:genetics; D005347:Fibroblasts / Q000502:physiology*; D015326:Gene Rearrangement, B-Lymphocyte, Heavy Chain; D051379:Mice; D008822:Mice, Transgenic; D051757:PAX5 Transcription Factor / Q000235:genetics / Q000378:metabolism; D039904:Pluripotent Stem Cells / Q000276:immunology / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D051757:PAX5 Transcription Factor; C497282:Pax5 protein, mouse; D014157:Transcription Factors