title: Survival and Histopathological Study of Animals Bearing Ehrlich Tumor Treated With a Rhodium(II) Amidate.
abstract: The survival of 90% of a tumor-bearing population treated with the complex Rh(2) (CF(3)CONH)(4) was examined and the pharmacological parameter Surv(90) determined. Histopathological alterations raised for this drug in several tissues were studied in Balb-c mice. A Surv(90) dose of 3.8x 10(-5) mol/kg was found.
authors.affiliation: University of São Paulo Institute of Chemistry Av. Prof. Lineu Prestes, 748 - r. 1265 São Paulo 055508-900 Brazil.
authors.forename: B P
authors.initials: BP
authors.lastname: Espósito
authors.forename: S B
authors.initials: SB
authors.lastname: Zyngier
authors.forename: R
authors.initials: R
authors.lastname: Najjar
authors.forename: R P
authors.initials: RP
authors.lastname: Paes
authors.forename: S M
authors.initials: SM
authors.lastname: Ueda
authors.forename: J C
authors.initials: JC
authors.lastname: Barros