Computational design of enzymes.
The de novo design of enzymes with activities not found in natural biocatalysts is a major challenge for molecular biology. Sophisticated computational methods have recently led to impressive progress in this exciting and rapidly evolving field (Röthlisberger et al., 2008; Jiang et al., 2008).
Sterner
Reinhard
R
Institute of Biophysics and Physical Biochemistry, University of Regensburg, Regensburg, Germany.
Merkl
Rainer
R
Raushel
Frank M
FM
D017076:Computer-Aided Design; D015195:Drug Design; D004798:Enzymes / Q000737:chemistry*
D004798:Enzymes