title: Late-onset infections after LASIK.
abstract: To report two cases of infectious keratitis that developed 2 and 6 years after LASIK.
  
  
  
  Case 1 was a 56-year-old woman who presented with redness and decreased vision in the right eye 6 years after LASIK. Slit-lamp examination revealed inflammation of the flap interface, a partially detached flap, anterior chamber reaction, and hypopyon. Corneal scrapings were taken. Case 2 was a 23-year-old woman who presented with pain and a corneal infiltrate in the left eye 36 hours after eye trauma. She had undergone bilateral LASIK 2 years prior. The condition worsened despite treatment, and a flap amputation was performed.
  
  
  
  Cultures revealed Pseudomonas mesophilic and Fusarium solani, respectively. Keratitis in case 1 resolved after 21 days of fortified antibiotic therapy. Visual acuity of 20/40 was achieved after antibiotic treatment in case 2.
  
  
  
  These case reports demonstrate the risk of microbial keratitis occurring years after LASIK and emphasize the need for lifelong postoperative vigilance by patient and physician.
authors.affiliation: Cornea and External Diseases Sector, Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil. carolvieira@superig.com.br
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Vieira
authors.forename: Telma
authors.initials: T
authors.lastname: Pereira
authors.forename: Denise
authors.initials: D
authors.lastname: de Freitas
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005670:Fusarium / Q000302:isolation & purification; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011549:Pseudomonas / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013524:Surgical Flaps / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents