title: A rare case of malignant solitary fibrous tumor of the spinal cord.
abstract: METHODS
  Case report.
  
  
  OBJECTIVE
  We present a case of an ambulatory patient with a solitary fibrous tumor of the spinal cord.
  
  
  BACKGROUND
  Solitary fibrous tumor (SFT) is an uncommon mesenchymal tumor of the pleural cavity, increasingly recognized at numerous extrathoracic sites, including, among others, prostate, kidney, and thyroid. The spinal cord is an extremely rare localization of SFTs with only 17 cases reported in the literature since 1996. Although SFTs are usually indolent neoplasms that are cured with complete surgical resection, malignant transformation has been described within histologically benign SFTs. However, no cases of malignant dissemination have been described in this localization.
  
  
  METHODS
  Discussion of the patient's clinical and radiologic history with a review of the relevant background literature.
  
  
  RESULTS
  We report the first case of spinal cord SFT with visceral dissemination years after the primary diagnosis, despite benign histologic features of the primary tumor.
  
  
  CONCLUSIONS
  This finding may indicate that long-term follow-up might be necessary in these patients. In addition, metastatic radical surgery of SFTs should be considered to achieve long-term survival since there are no currently available effective systemic therapies.
authors.affiliation: Vall d'Hebron University Hospital, Department of Medical Oncology, Barcelona, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Muñoz
authors.forename: Aleix
authors.initials: A
authors.lastname: Prat
authors.forename: Barbara
authors.initials: B
authors.lastname: Adamo
authors.forename: Sergio
authors.initials: S
authors.lastname: Peralta
authors.forename: Santiago
authors.initials: S
authors.lastname: Ramón y Cajal
authors.forename: Claudia
authors.initials: C
authors.lastname: Valverde
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008113:Liver Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D008175:Lung Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D019637:Orthopedic Procedures; D011013:Pneumonectomy; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D011878:Radiotherapy; D054364:Solitary Fibrous Tumors / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D013120:Spinal Cord Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis
chemical_list: D018952:Antigens, CD34; D019394:Ki-67 Antigen; D019253:Proto-Oncogene Proteins c-bcl-2; D014746:Vimentin