title: In-vivo imaging of carotid plaque neoangiogenesis with contrast-enhanced harmonic ultrasound.
abstract: We describe a case where a mild carotid atherosclerotic plaque was assessed by contrast enhanced harmonic ultrasonography and image analysis. Quantitative indices of plaque echogenicity were determined prior and after the injection of microbubbles. Changes in plaque echogenicity were detected possibly due to the flow of microbubbles through vasa vasorum within the plaque and at the plaque base at the adventitial level. Future histological studies remain to be done to link the presence and the extent of plaque and adventitial neovascularization with the visual and quantitative findings derived by contrast enhanced harmonic ultrasound and image analysis.
authors.forename: Theodore G
authors.initials: TG
authors.lastname: Papaioannou
authors.forename: Manolis
authors.initials: M
authors.lastname: Vavuranakis
authors.forename: Aristides
authors.initials: A
authors.lastname: Androulakis
authors.forename: George
authors.initials: G
authors.lastname: Lazaros
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kakadiaris
authors.forename: Ioannis
authors.initials: I
authors.lastname: Vlaseros
authors.forename: Morteza
authors.initials: M
authors.lastname: Naghavi
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kallikazaros
authors.forename: Christodoulos
authors.initials: C
authors.lastname: Stefanadis
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000150:complications / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000150:complications / Q000000981:diagnostic imaging*; D003287:Contrast Media; D006801:Humans; D008297:Male; D045423:Microbubbles; D009389:Neovascularization, Pathologic / Q000150:complications / Q000000981:diagnostic imaging*; D014463:Ultrasonography
chemical_list: D003287:Contrast Media