title: Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae.
abstract: The twin-Cx(9)C motif protein Pet191 is essential for cytochrome c oxidase maturation. The motif Cys residues are functionally important and appear to be present in disulfide linkages within a large oligomeric complex associated with the mitochondrial inner membrane. The import of Pet191 differs from that of other twin-Cx(9)C motif class of proteins in being independent of the Mia40 pathway.
authors.affiliation: University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
authors.forename: Oleh
authors.initials: O
authors.lastname: Khalimonchuk
authors.forename: Kevin
authors.initials: K
authors.lastname: Rigby
authors.forename: Megan
authors.initials: M
authors.lastname: Bestwick
authors.forename: Fabien
authors.initials: F
authors.lastname: Pierrel
authors.forename: Paul A
authors.initials: PA
authors.lastname: Cobine
authors.forename: Dennis R
authors.initials: DR
authors.lastname: Winge
mesh_terms: D020816:Amino Acid Motifs; D003576:Electron Transport Complex IV / Q000096:biosynthesis / Q000378:metabolism*; D004734:Energy Metabolism / Q000235:genetics; D015966:Gene Expression Regulation, Fungal / Q000235:genetics; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism / Q000648:ultrastructure; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics
chemical_list: D008565:Membrane Proteins; C532451:Pet191 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D003576:Electron Transport Complex IV