Polyomavirus infection of the urinary tract presenting as hemorrhagic cystitis in an immunocompetent five-year-old boy.
Human polyomavirus infection, which can be detected morphologically on Pap-stained routine urine cytology specimens, is most commonly encountered in immunocompromised patients and is a well-described complication of renal transplantation. We present a case of an immunocompetent 5-year-old boy with a sudden onset of dysuria and hematuria due to a self-limited polyomavirus urinary tract infection detected on routine urine cytology and confirmed with real-time PCR. Although rare cases of nonhemorrhagic cystitis have been reported, to the best of our knowledge this is the first case of hemorrhagic cystitis occurring in this setting.
Gonzalez
Jorge L
JL
Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA. jorge.gonzalez@hitchcock.org
Balestra
Suellen
S
Schned
Alan R
AR
Gutmann
Edward J
EJ
Tsongalis
Gregory J
GJ
D002472:Cell Transformation, Viral; D002675:Child, Preschool; D003556:Cystitis / Q000175:diagnosis* / Q000652:urine / Q000821:virology; D006417:Hematuria / Q000175:diagnosis; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D008297:Male; D011120:Polyomavirus / Q000472:pathogenicity; D027601:Polyomavirus Infections / Q000175:diagnosis* / Q000473:pathology / Q000652:urine / Q000821:virology; D014551:Urinary Tract / Q000473:pathology / Q000821:virology*; D014556:Urine / Q000166:cytology