title: Hualyzin, a symmetrical urea derivative isolated from Penicillium herquei isolate GA4.
abstract: Penicillium herquei isolate GA4 was isolated from the infected Conchocelis of Porphyra yezoensis. A large-scale fermentation using yeast extract sucrose medium and repeated chromatography afforded a new symmetrical urea derivative, hualyzin (1). The structure was determined by detailed NMR spectroscopic investigations and MS fragmentation analysis.
authors.affiliation: Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, 266071 Qingdao, People's Republic of China.
authors.forename: Ling
authors.initials: L
authors.lastname: Ding
authors.forename: Serge
authors.initials: S
authors.lastname: Fotso
authors.forename: Fuchao
authors.initials: F
authors.lastname: Li
authors.forename: Song
authors.initials: S
authors.lastname: Qin
authors.forename: Hartmut
authors.initials: H
authors.lastname: Laatsch
mesh_terms: D002681:China; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*; D044664:Porphyra / Q000382:microbiology; D014508:Urea / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C531267:hualyzin; D014508:Urea