Effect of vitamin E supplementation of sheep and goats fed diets supplemented with polyunsaturated fatty acids and low in Se.
Vitamin E (VitE) and selenium (Se) are an essential part of the antioxidative functions of metabolism. There are situations of low supply of both micronutrients. As VitE is involved in ruminal biohydrogenation of polyunsaturated fatty acids (PUFA) and their protection against oxidation in metabolism, diets supplemented with PUFA may challenge VitE to an extent making recommended supplies insufficient. Twelve goats and sheep each were fed a diet supplemented with PUFA and characterised by low Se and limited VitE contents during the last 2 months of gestation and the first 2 months of lactation. The basal diet consisted of hay and concentrate. Six goats and sheep received extra VitE, while the control groups received no extra VitE. Blood and milk samples were taken. In addition, liver, heart muscle and spleen samples were obtained from the offspring after slaughtering at an age of 8 weeks. No significant changes were observed in serum Se and VitE. A significant increase in serum VitE concentrations between 2 and 4 weeks postpartum (pp) was evident in the supplemented kids. In 4, 6 and 8 weeks pp, the serum concentrations of VitE in the supplemented kids were significantly higher compared to the unsupplemented group. In the kids, VitE was higher in liver of the supplemented groups. There were no significant differences in response to extra VitE between sheep and goat. The kids responded to serum VitE different from that of lambs, as a significant difference was observed between supplemented and unsupplemented animals in the goat kids, but not the lambs. In conclusion, goats and sheep have to be viewed differently and may not be considered alike relating to VitE/Se metabolism and requirements, especially in young animals.
Liesegang
A
A
Institute of Animal Nutrition, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland. aliese@vetphys.uzh.ch
Staub
T
T
Wichert
B
B
Wanner
M
M
Kreuzer
M
M
D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000833:Animals, Suckling; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage* / Q000378:metabolism; D005260:Female; D006041:Goats / Q000378:metabolism*; D007774:Lactation / Q000378:metabolism; D008892:Milk / Q000737:chemistry; D009751:Nutritional Requirements; D010084:Oxidation-Reduction; D011247:Pregnancy; D011897:Random Allocation; D012643:Selenium / Q000008:administration & dosage* / Q000172:deficiency* / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*; D013045:Species Specificity; D014810:Vitamin E / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*
D005231:Fatty Acids, Unsaturated; D014810:Vitamin E; D012643:Selenium