[Recent advance and prospect on taxol production by endophytic fungus fermentation--a review].
Taxol has become a widely used clinical anti-cancer drug. Due to the scaricity of Taxus trees, current taxol output cannot meet the requirement of the market. Taxol produced by endophytic fungus fermentation has high prospective. We reviewed advantages of taxol production by fungus fermentation, research advances of isolation, biodiversity of taxol-producing fungi and methods of improved taxol output by endophytic fungus fermentation.
Zhao
Kai
K
Laboratory of Microbiology, College of Life Science, Heilongjiang University, Harbin 150080, China. zk395@yahoo.com.cn
Ping
Wenxiang
W
Zhou
Dongpo
D
D000970:Antineoplastic Agents / Q000378:metabolism*; D044822:Biodiversity; D005285:Fermentation; D005658:Fungi / Q000378:metabolism*; D017239:Paclitaxel / Q000096:biosynthesis*
D000970:Antineoplastic Agents; D017239:Paclitaxel