Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate.
Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded bla(OXA-58) gene that was 100% homologous to the same gene in Acinetobacter baumannii.
Marti
Sara
S
Servei de Microbiologia, Centre de Diagnóstic Biomèdic, Hospital Clínic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.
Sánchez-Céspedes
Javier
J
Blasco
M Dolores
MD
Ruiz
Marc
M
Espinal
Paula
P
Alba
Verónica
V
Fernández-Cuenca
Felipe
F
Pascual
Alvaro
A
Vila
Jordi
J
D000150:Acinetobacter / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D000151:Acinetobacter Infections / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D015780:Carbapenems / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015780:Carbapenems; D015378:Imipenem; D001618:beta-Lactamases; C509061:beta-lactamase OXA-58, Acinetobacter junii