Ribosomal peptide-bond formation.
In this issue of Chemistry & Biology, Lang et al. (2008) add an important step toward a molecular understanding of ribosomal peptide-bond formation: they unravel the involvement of an essential partner of the reaction, namely the 2'-OH group of the 23S rRNA nucleotide A2451.
Pech
Markus
M
Max-Planck-Institut für Molekulare Genetik, Berlin, Germany.
Nierhaus
Knud H
KH
D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation; D012269:Ribosomal Proteins / Q000737:chemistry / Q000378:metabolism*
D010455:Peptides; D012269:Ribosomal Proteins