Three-dimensional sonography with needle tracking: role in diagnosis and treatment of prostate cancer.
OBJECTIVE
Image-guided prostate biopsy has become routine in medical diagnosis. Although it improves biopsy outcome, it mostly operates in 2 dimensions, therefore lacking presentation of information in the complete 3-dimensional (3D) space. Because prostatic carcinomas are nonuniformly distributed within the prostate gland, it is crucial to accurately guide the needles toward clinically important locations within the 3D volume for both diagnosis and treatment.


METHODS
We reviewed the uses of 3D image-guided needle procedures in prostate cancer diagnosis and cancer therapy as well as their advantages, work flow, and future directions.


RESULTS
Guided procedures for the prostate rely on accurate 3D target identification and needle navigation. This 3D approach has potential for better disease diagnosis and therapy. Additionally, when fusing together different imaging modalities and cancer probability maps obtained from a population of interest, physicians can potentially place biopsy needles and other interventional devices more accurately and efficiently by better targeting regions that are likely to host cancerous tissue.


CONCLUSIONS
With the information from anatomic, metabolic, functional, biochemical, and biomechanical statuses of different regions of the entire gland, prostate cancers will be better diagnosed and treated with improved work flow.
Shen
Feimo
F
Eigen LLC, 13366 Grass Valley Ave, Grass Valley, CA 95945 USA.
Shinohara
Katsuto
K
Kumar
Dinesh
D
Khemka
Animesh
A
Simoneau
Anne R
AR
Werahera
Priya N
PN
Li
Lu
L
Guo
Yujun
Y
Narayanan
Ramkrishnan
R
Wei
Liyang
L
Barqawi
Al
A
Crawford
E David
ED
Davatzikos
Christos
C
Suri
Jasjit S
JS
D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D018084:Ultrasonography, Interventional