title: Paraganglioma: a potentially challenging tumor.
abstract: Paragangliomas are usually low-grade neoplasms with a benign natural history. While the treatment of paraganglioma has historically been controversial, surgery and radiotherapy have become standardized as therapies of choice for primary therapy. More recently, stereotactic radiosurgery has been used effectively against this rare tumor. The development of metastatic disease in patients with paraganglioma is an unusual and challenging event. This case report and review describes the specific features of this disease and the multiple therapeutic options.
authors.affiliation: Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA. mtrombet@wpahs.org
authors.forename: Mark
authors.initials: M
authors.lastname: Trombetta
authors.forename: Jan
authors.initials: J
authors.lastname: Silverman
authors.forename: Athanasios
authors.initials: A
authors.lastname: Colonias
authors.forename: Vincent
authors.initials: V
authors.lastname: Lee
authors.forename: Alok
authors.initials: A
authors.lastname: Mohanty
authors.forename: David
authors.initials: D
authors.lastname: Parda
mesh_terms: D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010235:Paraganglioma / Q000175:diagnosis* / Q000628:therapy*