title: Orbital solitary fibrous tumor: a case report and review of the literature.
abstract: Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm typically arising in the pleura and involving the orbit as its most common extra-pleural location. We herein describe a well documented case of orbital SFT arising in a 62-year-old woman presenting with progressive swelling of the right upper eyelid and proptosis. The tumor had a benign clinical course, with radical surgical excision followed by regression of the clinical symptoms. We review the clinical, histopathological, and immunohistochemical features of the orbital SFT described so far, with particular emphasis on differential diagnosis with other spindle cell orbital neoplasms.
authors.affiliation: Department of Human Pathology and Oncology, University of Florence, Viale GB Morgagni 85, 50134, Florence, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Leoncini
authors.forename: Vincenza
authors.initials: V
authors.lastname: Maio
authors.forename: Marco
authors.initials: M
authors.lastname: Puccioni
authors.forename: Alessandro
authors.initials: A
authors.lastname: Franchi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Giorgi
authors.forename: Francesca
authors.initials: F
authors.lastname: Ucci
authors.forename: Marco
authors.initials: M
authors.lastname: Santucci
authors.forename: Daniela
authors.initials: D
authors.lastname: Massi
mesh_terms: D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D054364:Solitary Fibrous Tumors / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed