[Q-T interval dispersion in patients with coronary heart disease in various terms after angioplastic revascularization].
According to epidemiological researches data, in 75-80% of coronary heart disease (CHD) cases, the cause of sudden death is ventricular rhythm disturbances. Degree of coronary arteries lesion plays an important role in development of these disturbances. Study of Q-T interval dispersion is one of prospective methods of noninvasive assessment of risk of occurrence of dangerous for life ventricular arrhythmias. The authors studied indices of Q-T interval end its parts dispersion in patients with coronary atherosclerosis, and also estimated influence of angioplastic myocardial revasculization on electrical instability markers during 6 months after intracoronary intervention. It was proved that coronary atherosclerosis in patients with CHD contributes to increase of degree of myocardial depolarization and repolarization nonhomogeneity. Value of Q-T interval and its parts dispersion does not depend on number of affected coronary arteries. Revascularization of myocardium contributes to reliable decrease of Q-T interval and its parts dispersion. More marked its decrease is registered in 6 months after transcutaneous intracoronary intervention. Development of restenosis is accompanied by increase of indices of Q-T interval and its parts dispersion.
Kuzubova
A V
AV
Afanas'ev
Iu I
IuI
Grigorova
S Iu
SIu
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D003327:Coronary Disease / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D018450:Disease Progression; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000379:methods; D011379:Prognosis; D012720:Severity of Illness Index