title: Urodynamic leak point pressures weakly correlate with subjective urinary incontinence severity.
abstract: OBJECTIVE
  To evaluate preoperative abdominal leak point pressures (ALPP) with pre- and postoperative Incontinence Severity Index (ISI) scores.
  
  
  METHODS
  A review of women who underwent a midurethral sling procedure between August 2004 and April 2006 was conducted. Eligible women completed preoperative urodynamic testing with ALPP determination and subjective incontinence severity assessment using the ISI before and 6 weeks after surgery. The ISI and ALPP relationship was analyzed using a Spearman rank correlation (Rho).
  
  
  RESULTS
  Ninety-nine women met the inclusion criteria. Mean ALPP was 77.7 (25-172 cm H2O). Mean improvement in ISI following surgery was 4 (-8 to 12). ALPP correlated with preoperative ISI (Spearman Rho -0.28, P=0.01), preoperative leakage frequency (ISI question 1) (Spearman Rho -0.32, P=0.001), and the ISI change 6 weeks postoperatively (ISI-delta) (Spearman Rho -0.23, P=0.002).
  
  
  CONCLUSIONS
  ALPP is associated with subjective incontinence severity. Women with the lowest ALPP improved most following a midurethral sling procedure.
authors.affiliation: Department of Gynecology and Obstetrics, Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Cara L
authors.initials: CL
authors.lastname: Grimes
authors.forename: Paul D
authors.initials: PD
authors.lastname: Hanissian
authors.forename: Kris
authors.initials: K
authors.lastname: Strohbehn
authors.forename: Marlene B
authors.initials: MB
authors.lastname: Goldman
authors.forename: James L
authors.initials: JL
authors.lastname: Whiteside
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014550:Urinary Incontinence, Stress / Q000503:physiopathology*; D014563:Urodynamics