title: Chemical synthesis of cyclic galactooligofuranosides isolated from enzymatic degradation products of cell wall arabinogalactan of Mycobacterium tuberculosis.
abstract: Synthesis of cyclic tetra-, hexa- and octasaccharides containing alternating (1-->5)-beta- and (1-->6)-beta-galactofuranosyl linkages has been achieved by intramolecular cycloglycosylation of corresponding linear sugars and by cyclooligomerization of 1,6-linked and 1,5-linked disaccharides. In particular, cyclooligomerization of the (1-->6)-beta-galactofuranosyl disaccharide provides an efficient way to secure all three cyclic sugars in one operation.
authors.affiliation: Center for Bioactive Molecular Hybrids and Department of Chemistry, Yonsei University, Seoul, Korea. kwan@yonsei.ac.kr
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Kim
authors.forename: Bo-Young
authors.initials: BY
authors.lastname: Lee
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Yoon
authors.forename: Hyo Jin
authors.initials: HJ
authors.lastname: Jeon
authors.forename: Ju Yuel
authors.initials: JY
authors.lastname: Baek
authors.forename: Kyu-Sung
authors.initials: KS
authors.lastname: Jeong
mesh_terms: D002473:Cell Wall / Q000737:chemistry* / Q000378:metabolism; D003500:Cyclization; D005685:Galactans / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000737:chemistry* / Q000378:metabolism; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D005685:Galactans; D011135:Polysaccharides, Bacterial; C005653:arabinogalactan