Analysis of cerebrospinal fluid in healthy rabbits and rabbits with clinically suspected encephalitozoonosis.
Samples of uncontaminated cerebrospinal fluid (csf) were collected from the cisterna magna of 20 healthy laboratory rabbits and 21 pet rabbits with vestibular disease and/or paresis due to clinically suspected encephalitozoonosis. In the healthy rabbits' csf the leucocyte count was <or=4 leucocytes/microl (median 1.5 microl) and the concentration of protein ranged from 0.13 to 0.31 g/l (median 0.24 g/l). In the diseased rabbits, the number of leucocytes ranged from 1 to 87/microl (median 15/microl; P<0.001), and the concentration of protein ranged from 0.31 to 1.54 g/l (median 0.79 g/l; P<0.001); a cytological evaluation showed that they had greater numbers of lymphocytes and monocytes. It was concluded that encephalitozoonosis in rabbits is characterised by lymphomonocytic pleocytosis in CSF.
Jass
A
A
Clinic of Small Animal Medicine, Faculty of Veterinary Medicine, Ludwig Maximilian University Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Matiasek
K
K
Henke
J
J
Küchenhoff
H
H
Hartmann
K
K
Fischer
A
A
D000818:Animals; D000908:Antibodies, Fungal / Q000097:blood; D002555:Cerebrospinal Fluid / Q000166:cytology / Q000276:immunology / Q000382:microbiology*; D009670:Encephalitozoon cuniculi / Q000276:immunology / Q000302:isolation & purification; D016890:Encephalitozoonosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000401:mortality / Q000662:veterinary*; D007958:Leukocyte Count; D011817:Rabbits / Q000134:cerebrospinal fluid* / Q000382:microbiology; D012016:Reference Values; D014556:Urine / Q000382:microbiology
D000908:Antibodies, Fungal