title: Development of Acid-Sensitive Platinum(II) Complexes With Protein-Binding Properties.
abstract: Four new protein-binding platinum(II) complexes, 10, 11, 21, 22, in which the dichloroplatinum moiety is coordinated either to a carbon-substituted or a nitrogen-substituted ethylene diamino ligand, were prepared in ten-step syntheses. According to pH-dependent stability studies with strictly related compounds, 11 and 22 exhibit acid-sensitive properties.
authors.affiliation: Institute of Macromolecular Chemistry University of Freiburg Stefan-Meier-Straße 31 Freiburg 79104 Germany.
authors.forename: M T
authors.initials: MT
authors.lastname: Schütte
authors.forename: R
authors.initials: R
authors.lastname: Mülhaupt
authors.forename: F
authors.initials: F
authors.lastname: Kratz