title: Influence of an interpositional spacer on the behaviour of the tibiofemoral joint: a finite element study.
abstract: BACKGROUND
  Interpositional arthroplasty is considered by many surgeons for the treatment of isolated medial compartment osteoarthritis of the knee. In this procedure, an interpositional spacer is inserted into the medial compartment of the joint with no bone resection and no mechanical fixation. Major problems such as implant dislocation, severe pain or need for revision have been reported post-operatively.
  
  
  METHODS
  In this study, the kinematics of a knee implanted with an interpositional spacer made of either polyurethane or cobalt-chrome during walking, stair ascent and squatting cycles have been predicted and compared to the normal knee using finite element analysis. In addition, articular cartilage stress histories have been examined to obtain distributions of cumulative stress, a measure of the likelihood of articular cartilage degeneration.
  
  
  RESULTS
  The insertion of a polyurethane interpositional spacer in the medial side of the knee did not affect knee kinematics as compared to the normal knee, but caused an increase of articular cartilage cumulative contact stress exposures in the medial compartment of the joint. The knee implanted with the Co-Cr spacer exhibited similar trends in knee kinematics, however significantly different ranges of motion were observed during some periods of the activity cycles, specifically during the first half of the walking cycle where lower ranges of motion were predicted. In addition, higher articular cartilage cumulative contact stress exposures were observed in both compartments of the knee. In both cases, cumulative contact stress exposures of the tibial articular cartilage were more affected than those of the femoral articular cartilage.
  
  
  CONCLUSIONS
  These results suggest implant material as an important parameter in the design phase of interpositional spacers.
authors.affiliation: Trinity Centre for Bioengineering, School of Engineering, Parsons Building, Trinity College, Dublin 2, Ireland. s.checa@tcd.ie
authors.forename: S
authors.initials: S
authors.lastname: Checa
authors.forename: M
authors.initials: M
authors.lastname: Taylor
authors.forename: A
authors.initials: A
authors.lastname: New
mesh_terms: D001178:Arthroplasty / Q000295:instrumentation / Q000379:methods; D002358:Cartilage, Articular / Q000503:physiopathology / Q000601:surgery; D005269:Femur / Q000502:physiology / Q000601:surgery*; D020342:Finite Element Analysis; D006801:Humans; D007717:Knee / Q000502:physiology / Q000601:surgery*; D007719:Knee Joint / Q000502:physiology / Q000601:surgery*; D007720:Knee Prosthesis; D011237:Predictive Value of Tests; D016059:Range of Motion, Articular / Q000502:physiology; D013314:Stress, Mechanical; D013977:Tibia / Q000502:physiology / Q000601:surgery*; D016138:Walking / Q000502:physiology