Genetic instability is not a requirement for tumor development.
Bodmer
Walter
W
Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, United Kingdom.
Bielas
Jason H
JH
Beckman
Robert A
RA
D020137:Base Pair Mismatch; D002471:Cell Transformation, Neoplastic; D004777:Environment; D044127:Epigenesis, Genetic; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D008954:Models, Biological; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D010641:Phenotype; D012641:Selection, Genetic