title: Coronary artery bypass grafting is associated with excellent long-term survival and quality of life: a prospective cohort study.
abstract: BACKGROUND
  We investigated the long-term outcome of coronary artery bypass grafting both in terms of survival and quality of life.
  
  
  METHODS
  Ten-year postsurgery survival was collated on patients undergoing coronary artery bypass grafting from 1994 to 1996, and quality of life was assessed using EQ-5D and a quality-of-life thermometer. We analyzed data from 1,180 patients. Mean age was 61 years, and 79% had triple-vessel disease.
  
  
  RESULTS
  Thirty-day mortality was 3.3% (1.8% elective). Mean time to censorship for survivors was 9.9 years (range, 8.1 to 12.3 years). Ten-year survival was 66% across all patients, 70% for elective patients. Ten-year cardiac survival was 82%. Percutaneous intervention was required in 25 patients in the subsequent 10 years (2%), and only 4 required redo coronary artery bypass grafting (0.3%); 59% of patients reported no angina, and 88% of patients had grade II angina or better. Of 621 patients who were assessed for quality of life at 10 years, 530 (85%) had a quality of life within a 95% confidence interval of the score found in the general population with similar age. Poor quality of life was reported in 91 patients (14.7%). Significant predictors of poor long-term quality of life were current smoking, Canadian Cardiovascular Society grade III or IV, redo operation, female sex, diabetes, peripheral vascular disease, more than 2 days in intensive care, and chronic obstructive pulmonary disease. Twenty-five percent of patients with poor EQ-5D outcome had grade IV angina. Interestingly, age did not correlate with poor outcome, and administration of blood, arterial revascularization, left mainstem disease, or cross-clamp fibrillation had no impact on survival or outcome.
  
  
  CONCLUSIONS
  Coronary artery bypass grafting is associated with excellent 10-year survival and quality of life.
authors.affiliation: Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough, United Kingdom. joeldunning@doctors.org.uk
authors.forename: Joel
authors.initials: J
authors.lastname: Dunning
authors.forename: Julian R L
authors.initials: JR
authors.lastname: Waller
authors.forename: Barbara
authors.initials: B
authors.lastname: Smith
authors.forename: Sue
authors.initials: S
authors.lastname: Pitts
authors.forename: Simon W H
authors.initials: SW
authors.lastname: Kendall
authors.forename: Khalid
authors.initials: K
authors.lastname: Khan
mesh_terms: D000368:Aged; D002423:Cause of Death; D015331:Cohort Studies; D015897:Comorbidity; D001026:Coronary Artery Bypass / Q000523:psychology; D004739:England; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000401:mortality* / Q000523:psychology / Q000601:surgery; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D012086:Reoperation; D016019:Survival Analysis; D015996:Survival Rate