[Comparative experimental morphological study of the impact of various drainages for cyclodialysis to the adjacent tissues].
The investigation was made on 8 eyes (4 rabbits) undergone cyclodialysis with the hydrogen or collagenic drainage being introduced into the supraciliary cleft. Comparative pathohistological study indicated the evident advantages of a hydrogel implant ensuring the drainage function of the formed cyclodialysis cleft throughout the experiment (5 weeks). By contrast, subject to resolution, the collagenic drainage spurred the early development of young connective tissue in the cyclodialysis cleft just on day 14 after implantation. Complete atresia of the cyclodialysis cleft and cessation of its drainage function might be suggested by week 3. Moreover, hydrogel material has, in our opinion, a less noticeable irritating effect on the adjacent tissues and causes minimum inflammatory and fibroplastic reactions.
Bakharev
A V
AV
Fedorov
A A
AA
Batmanov
Iu E
IuE
D000818:Animals; D000867:Anterior Chamber / Q000378:metabolism; D001082:Aqueous Humor / Q000378:metabolism*; D002829:Choroid / Q000378:metabolism / Q000601:surgery*; D002924:Ciliary Body / Q000378:metabolism / Q000601:surgery*; D004195:Disease Models, Animal; D018463:Filtering Surgery / Q000379:methods*; D005500:Follow-Up Studies; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D009798:Ocular Hypertension / Q000601:surgery*; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation*; D011817:Rabbits; D016896:Treatment Outcome; D014945:Wound Healing
D020136:Hydrogel, Polyethylene Glycol Dimethacrylate