Structure elucidation and complete NMR spectral assignments of two new dammarane-type tetraglycosides from Panax quinquefolium.
Two new saponins were isolated from leaves of Panax quinquefolium and their structures were elucidated as 3beta, 12beta, 20S-trihydroxy-25-methoxydammar-23-ene 3-O-{[beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranosyl]-20-O-[alpha-L-arabinopyranosyl(1-->6)]-beta-D-glucopyranoside (1) and 3beta, 20S-dihydroxy-12beta, 23R-epoxydammar-24-ene 3-O-{[beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranosyl]-20-O-[beta-D-xylopyanosyl(1-->6)]-beta-D-glucopyranoside (2) on the basis of (1)D and (2)D NMR (including (1)H, (13)C-NMR, (1)H-(1)H COSY, HSQC, TOCSY, HMBC, and NOESY), ESI-MS spectrometry and chemical methods.
Jiang
Hai-Ping
HP
College of Pharmacy, Liaoning University of Traditional Chinese Medicine, 77 Life one Road, DD Port, Dalian 116600, China.
Qiu
Ying-Kun
YK
Cheng
Da-Ren
DR
Kang
Ting-Guo
TG
Dou
De-Qiang
DQ
D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D005894:Panax / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000097669:Dammaranes
D006027:Glycosides; D014315:Triterpenes; D000097669:Dammaranes