Comparison of information content for microsatellites and SNPs in poultry and cattle.
Data were available for 12 poultry microsatellites and 29 poultry single nucleotide polymorphisms (SNPs), and for 34 cattle microsatellites and 36 cattle SNPs. Stochastic permutation was used to determine the number of SNPs needed to obtain the same average information content as a given number of microsatellites. For poultry, the information content averaged 0.71 for the 12 microsatellites compared to 0.72 for the 29 SNPs. For cattle, the information content averaged 0.92 for the 34 microsatellites compared with 0.79 for the 36 SNPs. This study shows that, for each microsatellite, three SNPs are needed to obtain the same average information content.
Schopen
G C B
GC
Animal Breeding and Genomics Centre, Wageningen University, Wageningen, 6700 AH, The Netherlands. ghyslaine.schopen@wur.nl
Bovenhuis
H
H
Visker
M H P W
MH
van Arendonk
J A M
JA
D000818:Animals; D002417:Cattle / Q000235:genetics*; D002645:Chickens / Q000235:genetics*; D005819:Genetic Markers; D005838:Genotype; D018895:Microsatellite Repeats; D020641:Polymorphism, Single Nucleotide; D013269:Stochastic Processes
D005819:Genetic Markers