title: Ulcerative lichen planus of the sole: excellent response to topical tacrolimus.
abstract: Ulcerative lichen planus of the sole is a rare variant of lichen planus, characterized by chronic painful disabling ulceration of the soles. Despite many treatment modalities used to treat ulcerative lichen planus, it is still considered a resistant disease. We report a Saudi female patient with ulcerative lichen planus of the soles resistant to many systemic and topical agents. We used topical tacrolimus 0.1% ointment with excellent response and complete healing in a few weeks as well as good maintenance during a follow-up period of more than 2 years.
authors.affiliation: Division of Dermatology, Department of Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia. khenaizans@ngha.med.sa
authors.forename: Sultan
authors.initials: S
authors.lastname: Al-Khenaizan
authors.forename: Luluah
authors.initials: L
authors.lastname: Al Mubarak
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D005260:Female; D005528:Foot / Q000473:pathology; D005533:Foot Dermatoses / Q000188:drug therapy* / Q000473:pathology; D016523:Foot Ulcer / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008010:Lichen Planus / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology; D016559:Tacrolimus / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus