title: Long-term endothelial cell loss after traumatic dislocation and repositioning of Artisan phakic IOL.
abstract: To evaluate long-term endothelial cell loss after traumatic dislocation and repositioning of an Artisan phakic intraocular lens (PIOL).
  
  
  
  Traumatic PIOL dislocation occurred in the patient's left eye 4 months after uneventful implantation for unilateral congenital myopia. Using the Konan semi-automated analysis method, endothelial cell density was measured preoperatively, before Artisan repositioning, and 1, 2, and 4 years after primary implantation.
  
  
  
  Endothelial cell density was 2770 cells/mm2 preoperatively and 2634 cells/mm2 before Artisan repositioning. After successful repositioning, endothelial cell density progressively decreased--1, 2, and 4 years from primary implantation, endothelial cell density was 2582, 2524, and 2538 cells/mm2, respectively, corresponding to losses of 6.8%, 8.9%, and 8.4%, respectively.
  
  
  
  Progressive and long-term endothelial loss after traumatic dislocation and repositioning of the Artisan PIOL may be comparable to that reported after uneventful implantation.
authors.affiliation: Department of Clinical Physiopathology, Ophthalmology Institute, Turin University, Turin, Italy. ugo.desanctis@unito.it
authors.forename: Ugo
authors.initials: U
authors.lastname: de Sanctis
authors.forename: Bernardo
authors.initials: B
authors.lastname: Mutani
authors.forename: Federico M
authors.initials: FM
authors.lastname: Grignolo
mesh_terms: D000328:Adult; D002452:Cell Count; D004728:Endothelium, Corneal / Q000473:pathology*; D005131:Eye Injuries / Q000150:complications*; D005500:Follow-Up Studies; D005548:Foreign-Body Migration / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D009216:Myopia / Q000151:congenital / Q000601:surgery; D012086:Reoperation; D014949:Wounds, Nonpenetrating / Q000150:complications*