title: [Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis].
abstract: OBJECTIVE
  The objective of the study is to verify the clinical effectiveness of a cream containing lactoferrin in the treatment of acute vulvovagininal candidiasis.
  
  
  METHODS
  The study enrolled 34 patients aged 25-45 years and preenting signs and symptoms of acute vulvovaginal candidiasis. The patients have been treated with a cream containing lactoferrin 4%, 5 g of cream in vagina and 2 cm applied on the vulva twice a day for 7 days. At the end of the treatment the patients a clinical and microscopical examination was performed in order to evaluate the effectiveness of the therapy.
  
  
  RESULTS
  The results obtained showed that 27 women completely recovered, 5 showed a good improvement and only 2 women were still suffering from vulvovaginitis at the end of treatment.
  
  
  CONCLUSIONS
  From the data of our study, a cream containing lactoferrin seems to be clinically effective in the treatment of acute vulvovaginal candidiasis, with a good response on all the characteristic symptoms of this infection.
authors.affiliation: Centro Salute Donna, Azienda USL, Ferrara, Italia. kostin@alice.it
authors.forename: D
authors.initials: D
authors.lastname: Costantino
authors.forename: C
authors.initials: C
authors.lastname: Guaraldi
mesh_terms: D000328:Adult; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007781:Lactoferrin / Q000627:therapeutic use*; D008875:Middle Aged; D014622:Vaginal Creams, Foams, and Jellies
chemical_list: D014622:Vaginal Creams, Foams, and Jellies; D007781:Lactoferrin