title: Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable.
abstract: Multiple sclerosis is a heterogeneous disease with varying clinical picture. There have been substantial efforts to develop outcome measurements for therapeutic interventions but very few studies have addressed the value of bodily functions from the patient perspective. In a randomly selected cohort of early (<5 years, n=84) and longer lasting disease courses (>15 years, n=82) patients we asked for a weighting of 13 bodily functions and compared results with actual disability as measured by the United Kingdom Disability Scale. Lower limb function was given the highest priority in both patient groups followed by visual functioning and cognition especially in longer lasting MS. Actual disability did not correlate with the given priorities indicating that experienced deficits do not influence the subjective ratings of bodily functions. These results underline that ambulation-focused scales in MS represent a key dimension from the patient perspective. Visual functioning should be taken more into account.
authors.affiliation: Institute of Neuroimmunology and Clinical MS Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. heesen@uke.uni-hamburg.de
authors.forename: C
authors.initials: C
authors.lastname: Heesen
authors.forename: J
authors.initials: J
authors.lastname: Böhm
authors.forename: C
authors.initials: C
authors.lastname: Reich
authors.forename: J
authors.initials: J
authors.lastname: Kasper
authors.forename: M
authors.initials: M
authors.lastname: Goebel
authors.forename: S M
authors.initials: SM
authors.lastname: Gold
mesh_terms: D000293:Adolescent; D000328:Adult; D004185:Disability Evaluation; D006233:Persons with Disabilities / Q000523:psychology*; D005684:Gait; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology / Q000523:psychology*; D010465:Perception; D011795:Surveys and Questionnaires; D006113:United Kingdom; D014785:Vision, Ocular