title: Eosinophilic esophagitis in children: clinical manifestations.
abstract: During the past decade, the increasing number of recognized cases of eosinophilic esophagitis in children and adults has resulted in a dramatic expansion of the medical literature surrounding it. Clinical and basic research has contributed to a better, but still incomplete, body of knowledge regarding its clinical and histologic manifestations, as well as its immunologic and genetic pathogenesis. This article provides a broad framework for recognizing the remarkable variety of clinical manifestations of eosinophilic esophagitis in children, which must be considered as part of the differential diagnosis in many different clinical situations.
authors.affiliation: Cincinnati Center for Eosinophilic Disorders, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. phil.putnam@cchmc.org
authors.forename: Philip E
authors.initials: PE
authors.lastname: Putnam
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004802:Eosinophilia; D004941:Esophagitis / Q000150:complications* / Q000473:pathology*; D006801:Humans; D010641:Phenotype; D012140:Respiratory Tract Diseases / Q000150:complications*; D012307:Risk Factors