title: Expansile properties of otowicks: an in vitro study.
abstract: OBJECTIVE
  To determine the expansile and absorptive properties of the expandable ear wick when tested with commonly prescribed ear drop preparations.
  
  
  METHODS
  This in vitro study assessed wick expansion and absorption of drops when different ear drop preparations were applied. Nine commonly used ear drop preparations were tested (Gentisone HC, Sofradex, Otomize, Betnesol, Exocin, Canesten, Locorten-Vioform, EarCalm and ichthammol glycerin) with a standard expandable ear wick.
  
  
  METHODS
  Weight, length and width of otowick following exposure to ear drops.
  
  
  RESULTS
  There was a marked difference in the absorption and expansion of the otowick when different drops were used. This corresponded to the aqueous or oil base of each preparation. All aqueous ear drop preparations (i.e. Gentisone HC, Sofradex, Otomize, Betnesol, Exocin and EarCalm) produced similar rates of absorption into, and expansion of, the otowick. The oil-based ear drop preparations (i.e. Canesten, Locorten-Vioform and ichthammol glycerin) failed to expand the wick and showed poor rates of absorption into the wick.
  
  
  CONCLUSIONS
  Expandable ear wicks should only be used in conjunction with aqueous ear drops. When using expandable otowicks as an adjunct to treating fungal otitis externa, acetic acid ear drops should be prescribed, as all other anti-fungal drops are oil-based.
authors.affiliation: Department of ENT, Royal United Hospital Bath NHS Trust, Bath, UK. philip.clamp@nhs.net
authors.forename: P J
authors.initials: PJ
authors.lastname: Clamp
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D004338:Drug Combinations; D004427:Ear Diseases / Q000188:drug therapy*; D004867:Equipment Design / Q000592:standards; D005601:Framycetin / Q000008:administration & dosage; D005839:Gentamicins / Q000008:administration & dosage; D006096:Gramicidin / Q000008:administration & dosage; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D007322:Instillation, Drug; D009355:Neomycin / Q000008:administration & dosage; D010032:Otitis Externa / Q000188:drug therapy*; D013630:Tampons, Surgical; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D005839:Gentamicins; C071179:Otomize; C057138:gentisone HC; D006096:Gramicidin; D005601:Framycetin; C023881:Sofradex; D003907:Dexamethasone; D009355:Neomycin; D006854:Hydrocortisone