title: Transanal endoscopic microsurgery is a safe and reliable technique even for complex rectal lesions.
abstract: BACKGROUND
  Transanal endoscopic microsurgery (TEM) is a minimally invasive technique for the excision of rectal lesions, with lower morbidity and mortality rates than open surgery. Following advances in laparoscopic colorectal surgery and endoscopic mucosal resection, this study evaluated the safety and efficacy of TEM in the treatment of complex rectal lesions.
  
  
  METHODS
  All patients were entered into a prospective database. Complex lesions were identified as high (more than 15 cm from anorectal margin), large (maximum dimension over 8 cm), involving two or more rectal quadrants, or recurrent.
  
  
  RESULTS
  Seventy-one lesions (13 carcinomas and 58 tubulovillous adenomas) were identified. The median duration of operation was 60 (interquartile range (i.q.r.) 30-80) min, with an estimated median blood loss of 0 (i.q.r. 0-10) ml. Median hospital stay was 2 (i.q.r. 1-3) days. One patient developed postoperative urinary retention and one returned with rectal bleeding that did not require further surgery. Two patients developed rectal strictures after operation that were dilated successfully. There was no recurrence of benign lesions during a median follow-up of 21 (i.q.r. 6.5-35) months.
  
  
  CONCLUSIONS
  TEM is a safe technique with low associated morbidity, even when used to excise complex rectal lesions. As such it remains the treatment of choice for rectal lesions not requiring primary radical resection.
authors.affiliation: Department of Gastro-intestinal Surgery, Cheltenham General Hospital, Sandford Road, Cheltenham GL53 7AN, UK. Rosie_darwood@btinternet.com
authors.forename: R J
authors.initials: RJ
authors.lastname: Darwood
authors.forename: J M D
authors.initials: JM
authors.lastname: Wheeler
authors.forename: N R
authors.initials: NR
authors.lastname: Borley
mesh_terms: D018253:Adenoma, Villous / Q000601:surgery*; D016063:Blood Loss, Surgical; D002277:Carcinoma / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008866:Microsurgery / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology; D011351:Proctoscopy / Q000379:methods*; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000601:surgery*