TiO2 nanoparticles as a soft X-ray molecular probe.
This communication reports the development of a TiO2-streptavidin nanoconjugate as a new biological label for X-ray bio-imaging applications; this new probe, used in conjunction with the nanogold probe, will make it possible to obtain quantitative, high-resolution information about the location of proteins using X-ray microscopy.
Ashcroft
Jared M
JM
Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Gu
Weiwei
W
Zhang
Tierui
T
Hughes
Steven M
SM
Hartman
Keith B
KB
Hofmann
Cristina
C
Kanaras
Antonios G
AG
Kilcoyne
David A
DA
Le Gros
Mark
M
Yin
Yadong
Y
Alivisatos
A Paul
AP
Larabell
Carolyn A
CA
D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D017348:Microscopy, Electron, Scanning Transmission / Q000379:methods; D015335:Molecular Probes / Q000737:chemistry*; D015394:Molecular Structure; D010316:Particle Size; D019809:Streptavidin / Q000737:chemistry; D014025:Titanium / Q000737:chemistry*; D014965:X-Rays
D015335:Molecular Probes; C009495:titanium dioxide; D006046:Gold; D019809:Streptavidin; D014025:Titanium