Pulmonary lymphangitic sarcomatosis and a review of the literature.
Intrapulmonary spread of a sarcoma via lymphatics is a rare cause of death in a young adult. A 31-year old man was admitted to our hospital complaining of dyspnea and malaise of 2 months' duration. A chest radiography revealed bilateral hilar enlargement, and reticulonodular infiltrations. Thoracic CT-scans demonstrated mediastinal lymphadenopathy, thickening of interlobular septa, polygonal lines, and thickening of bronchovascular bundles. The diagnosis was made by open-lung biopsy. The patient died within 3 months after diagnosis. Pulmonary lymphangitic sarcomatosis is a rare but important manifestation of an angiosarcoma. Optimal treatment of these patients is not well defined, but a trial of chemotherapy may be warranted.
Gonlugur
Tanseli
T
Department of Chest Diseases, Canakkale State Hospital, 17100, Canakkale, Turkey.
Sapmaz
Feride
F
Katrancioglu
Ozgur
O
Gonlugur
Ugur
U
Elagoz
Sahende
S
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003593:Cytoplasm / Q000378:metabolism; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D010386:Pelvic Neoplasms / Q000175:diagnosis; D013902:Radiography, Thoracic / Q000379:methods; D012509:Sarcoma / Q000175:diagnosis* / Q000628:therapy*; D014057:Tomography, X-Ray Computed / Q000379:methods
D000970:Antineoplastic Agents