May-Thurner syndrome will be completed?
BACKGROUND
The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia.


OBJECTIVE
The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation.


METHODS
We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden.


CONCLUSIONS
Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.
De Bast
Yann
Y
Vascular Surgery department, Saint Anne Saint Remi Clinic, Brussels, Belgium. ydebast@hotmail.com
Dahin
Laurent
L
D000293:Adolescent; D000328:Adult; D005165:Factor V / Q000235:genetics*; D005260:Female; D005268:Femoral Vein; D006801:Humans; D007083:Iliac Artery; D007085:Ilium; D008161:Lumbosacral Region; D017354:Point Mutation; D011516:Prothrombin / Q000235:genetics*; D013577:Syndrome; D019851:Thrombophilia / Q000097:blood / Q000150:complications / Q000235:genetics; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics*; D055815:Young Adult
C095381:factor V Leiden; D005165:Factor V; D011516:Prothrombin