Towards the total synthesis of FD-838: modular enantioselective assembly of the core.
A rapid assembly of the tetracyclic core of FD-838, featuring a catalytic asymmetric Stetter reaction, is described.
Orellana
Arturo
A
Department of Chemistry, York University, 4700 Keele Street, Toronto, ON, Canada. aorellan@yorku.ca
Rovis
Tomislav
T
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D000900:Anti-Bacterial Agents; C529961:FD 838; D005663:Furans; D007093:Imidazoles