title: Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity.
abstract: BACKGROUND
  Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity.
  
  
  METHODS
  Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity.
  
  
  RESULTS
  Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups.
  
  
  CONCLUSIONS
  CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.
authors.affiliation: Department of Psychological Medicine, Otago University, Wellington, New Zealand. kate.scott@otago.ac.nz
authors.forename: K M
authors.initials: KM
authors.lastname: Scott
authors.forename: M
authors.initials: M
authors.lastname: Von Korff
authors.forename: J
authors.initials: J
authors.lastname: Alonso
authors.forename: M
authors.initials: M
authors.lastname: Angermeyer
authors.forename: E J
authors.initials: EJ
authors.lastname: Bromet
authors.forename: R
authors.initials: R
authors.lastname: Bruffaerts
authors.forename: G
authors.initials: G
authors.lastname: de Girolamo
authors.forename: R
authors.initials: R
authors.lastname: de Graaf
authors.forename: A
authors.initials: A
authors.lastname: Fernandez
authors.forename: O
authors.initials: O
authors.lastname: Gureje
authors.forename: Y
authors.initials: Y
authors.lastname: He
authors.forename: R C
authors.initials: RC
authors.lastname: Kessler
authors.forename: V
authors.initials: V
authors.lastname: Kovess
authors.forename: D
authors.initials: D
authors.lastname: Levinson
authors.forename: M E
authors.initials: ME
authors.lastname: Medina-Mora
authors.forename: Z
authors.initials: Z
authors.lastname: Mneimneh
authors.forename: M A
authors.initials: MA
authors.lastname: Oakley Browne
authors.forename: J
authors.initials: J
authors.lastname: Posada-Villa
authors.forename: H
authors.initials: H
authors.lastname: Tachimori
authors.forename: D
authors.initials: D
authors.lastname: Williams
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D002908:Chronic Disease / Q000453:epidemiology* / Q000523:psychology; D015897:Comorbidity; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors