title: Photo-pH dually modulated fluorescence switch based on DNA spatial nanodevice.
abstract: In this paper, we describe our strategy on the design, construction, and characterization of a novel molecular device. By integrating a photoregulated fluorescent switch and a DNA-based nanomachine, the distance-dependent FRET process between fluorescein and photochromic moieties can be further modulated by the spatial output of a unique proton-driven DNA manomachine. This device could be reversibly switched in a reliable manner, and the fluorescence variation behavior, exhibited by this dually modulated fluorescence switch, can also mimic the function of a Boolean logic operation.
authors.affiliation: National Centre for Nanoscience and Technology, Beijing, China.
authors.forename: Huajie
authors.initials: H
authors.lastname: Liu
authors.forename: Yucheng
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Wenxing
authors.initials: W
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Qu
authors.forename: Chen
authors.initials: C
authors.lastname: Chen
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Liu
authors.forename: Deqing
authors.initials: D
authors.lastname: Zhang
authors.forename: Daoben
authors.initials: D
authors.lastname: Zhu
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000528:radiation effects*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000528:radiation effects*; D006863:Hydrogen-Ion Concentration; D008027:Light; D015394:Molecular Structure; D036103:Nanotechnology / Q000379:methods*; D010777:Photochemistry
chemical_list: D005456:Fluorescent Dyes; D004247:DNA