An unbalanced translocation, der(17)t(1;17)(p13;p11.2), leads to heterozygous loss of TP53 and is associated with clinical evolution in myelodysplastic syndrome.
So
C C
CC
Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, S A R China. scc@pathology.hku.hk
Wan
T S K
TS
Ma
E S K
ES
Chan
L C
LC
D000368:Aged; D000740:Anemia / Q000235:genetics / Q000503:physiopathology; D020732:Cytogenetic Analysis / Q000379:methods; D018450:Disease Progression; D005260:Female; D017353:Gene Deletion; D016158:Genes, p53; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000175:diagnosis / Q000235:genetics*; D014178:Translocation, Genetic