title: The explosive-degrading cytochrome P450 system is highly conserved among strains of Rhodococcus spp.
abstract: Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a widely used explosive and a serious environmental pollutant. Nineteen strains of Rhodococcus spp. capable of utilizing RDX as the sole nitrogen source have been isolated. The cytochrome P450 system XplA-XplB, which is responsible for RDX breakdown, is present in 18 of these strains.
authors.affiliation: Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1TJ, United Kingdom.
authors.forename: Helena M B
authors.initials: HM
authors.lastname: Seth-Smith
authors.forename: James
authors.initials: J
authors.lastname: Edwards
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Rosser
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Rathbone
authors.forename: Neil C
authors.initials: NC
authors.lastname: Bruce
mesh_terms: D015373:Bacterial Typing Techniques; D001673:Biodegradation, Environmental; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism; D004269:DNA, Bacterial / Q000302:isolation & purification; D053834:Explosive Agents / Q000378:metabolism*; D009584:Nitrogen / Q000378:metabolism; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000302:isolation & purification; D012240:Rhodococcus / Q000145:classification / Q000201:enzymology* / Q000235:genetics; D017422:Sequence Analysis, DNA; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000378:metabolism*; D014227:Triazines / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D053834:Explosive Agents; D012336:RNA, Ribosomal, 16S; D012989:Soil Pollutants; D014227:Triazines; D003577:Cytochrome P-450 Enzyme System; D009584:Nitrogen; C009160:cyclonite