A Preparation of enantiomerically enriched axially chiral beta-diketimines: synthesis of (-)- and (+)-IAN amine.
The preparation of an enantiomerically enriched beta-diketimine composed of isoquinoline and 2-aminonaphthalene (IAN amine) is described, thereby offering new opportunities in the synthesis of nonracemic beta-diketimine- and pyridine-based chiral catalysts.
Luesse
Sarah B
SB
Department of Chemistry & Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235-1822, USA.
Counceller
Carla M
CM
Wilt
Jeremy C
JC
Perkins
Brittany R
BR
Johnston
Jeffrey N
JN
D015081:2-Naphthylamine / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007546:Isoquinolines / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013237:Stereoisomerism
D000588:Amines; D007546:Isoquinolines; D009281:Naphthalenes; D015081:2-Naphthylamine