Stereoselective synthesis of spirocyclopentanones via N-heterocyclic carbene-catalyzed reactions of enals and dienones.
Homoenolates generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis undergo a conjugate addition/cyclization sequence with cyclic dienones, culminating in the efficient synthesis of spirocyclopentanones.
Nair
Vijay
V
Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India. vijaynair_2001@yahoo.com
Babu
Beneesh Pattoorpadi
BP
Vellalath
Sreekumar
S
Suresh
Eringathodi
E