Consensus statement on genetic research in dementia.
In this article, the authors describe how the European Dementia Consensus Network developed a consensus on research ethics in dementia, taking into account the questions posed by the era of genetic research and its new research methods. The consensus process started with a Delphi procedure to analyze relevant stakeholders' positions by describing their statements on the possibilities and limitations of research into genetic determinants of Alzheimer disease and to describe and analyze the moral desirability of genetic research on Alzheimer disease. The conclusions drawn from the Delphi procedure fuelled the development of the consensus statement, which is presented in this paper. The consensus statement aims to stimulate ethically acceptable research in the field of dementia and the protection of vulnerable elderly patients with dementia from application of inadequate research methods or designs.
Olde Rikkert
Marcel G M
MG
Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. M.Olde-Rikkert@ger.umcn.nl
van der Vorm
Anco
A
Burns
Alistair
A
Dekkers
Wim
W
Robert
Philipp
P
Sartorius
Norman
N
Selmes
Jacques
J
Stoppe
Gabriela
G
Vernooij-Dassen
Myrra
M
Waldemar
Gunhild
G
D000544:Alzheimer Disease / Q000235:genetics*; D003219:Confidentiality / Q000941:ethics; D003697:Delphi Technique; D017041:Ethics Committees; D032984:Ethics, Research; D005060:Europe; D036281:Genetic Research / Q000941:ethics*; D006801:Humans; D007258:Informed Consent / Q000941:ethics; D016743:Mental Competency