Neurobiology of cognitive aging: insights from imaging genetics.
Over the last several years, neuroscientists have been increasingly using neuroimaging techniques to unravel the neurobiology underlying cognitive aging, and in more recent years to explore the role of genes on the variability of the aging process. One of the primary goals of this research is to identify proteins involved in cognitive aging with the hope that this would facilitate the development of novel treatments to combat cognitive impairment. Further, it is likely with early identification of susceptible individuals, early intervention through life-style changes and other methods could increase an individual's resilience to the effects of aging.
Mattay
Venkata S
VS
Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, MD 20892, USA. vsm@mail.nih.gov
Goldberg
Terry E
TE
Sambataro
Fabio
F
Weinberger
Daniel R
DR
D000375:Aging / Q000235:genetics* / Q000502:physiology*; D000818:Animals; D003071:Cognition / Q000502:physiology*; D006801:Humans; D007206:Individuality; D008279:Magnetic Resonance Imaging; D008967:Molecular Biology / Q000379:methods*; D009483:Neuropsychological Tests; D009435:Synaptic Transmission / Q000502:physiology