Assessing the risk to U.K. children from carbendazim residues in apple products.
We present a detailed study into the effects that uncertainty and variability have on the levels of dietary exposure of young children to carbendazim in a range of apple products, including raw apples, apple juice and processed apple foods. It is estimated that exposure is greater than the provisional EU acute reference dose of 0.02 mg/kg-bw/day on 0.29% of person days, although there is large uncertainty in the true number. The contribution from apple juice consumption appears to be significant. The issues presented are common to many dietary risk analysis problems, and the methods could be applied to any food group and chemical of interest.
Holmes
Mel
M
Central Science Laboratory, Sand Hutton, York.
Kennedy
Marc C
MC
Riccio
Rossella
R
Hart
Andy
A
D000969:Antinematodal Agents / Q000008:administration & dosage / Q000633:toxicity*; D001499:Bayes Theorem; D001562:Benzimidazoles / Q000008:administration & dosage / Q000633:toxicity*; D002219:Carbamates / Q000008:administration & dosage / Q000633:toxicity*; D002675:Child, Preschool; D004032:Diet; D004034:Diet Surveys; D005506:Food Contamination; D006801:Humans; D007223:Infant; D027845:Malus; D018570:Risk Assessment; D006113:United Kingdom
D000969:Antinematodal Agents; D001562:Benzimidazoles; D002219:Carbamates; C006698:carbendazim