Conjunctival condylomata acuminata.
OBJECTIVE
To report a case of sexually transmitted conjunctival squamous papillomas and to propose a new term for this condition.


METHODS
We report a case of a 31-year-old white woman who presented with bilateral exuberant conjunctival papillomas. Her medical history included biopsy-proven human papillomavirus-induced genital warts, of which she was currently having a recurrence. We treated her eyes with topical a-interferon 2b.


RESULTS
After treatment, there was significant reduction of the conjunctival lesions. Tissue from a conjunctival lesion of her left eye showed a papillary squamous proliferation with delicated fibrovascular cores and acanthotic epithelium containing binucleate cells and koilocytes. Molecular testing confirmed the lesion to harbor human papillomavirus type 11.


CONCLUSIONS
The term "condylomata acuminata" typically refers to anogenital warts. From the similarities between the conjunctival lesions described in this patient and typical genital warts, it is our recommendation to refer to these lesions as conjunctival condylomata acuminata. This diagnostic term connotes a sexually transmitted etiology and should alert the health care provider to look for possible asymptomatic genital warts on the patient or the patient's sexual partner.
Department of Ophthalmology, Virginia Commonwealth University, Richmond, VA, USA.
Joseph
J
Iuorno
Alexander
A
Truskinovsky
Gary
G
Chung
Jay
J
Krachmer
Drew
D
Bawcombe
Andrew
A
Huang
D000287:Administration, Topical; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000150:complications* / Q000473:pathology / Q000628:therapy; D003229:Conjunctival Diseases / Q000150:complications* / Q000473:pathology / Q000628:therapy; D015828:Eye Infections, Viral / Q000150:complications* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage; D009883:Ophthalmic Solutions; D013508:Ophthalmologic Surgical Procedures; D011994:Recombinant Proteins; D009626:Terminology as Topic
D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D009883:Ophthalmic Solutions; D011994:Recombinant Proteins