Chemokines as pharmacological targets.
Chemokines play a key role in immune processes by controlling leukocyte recruitment in physiological and pathological condition. This review discusses the regulation of the chemokine system, its role in human diseases, and its potential relevance as a new pharmacological target.
Galliera
Emanuela
E
Laboratory of Leukocyte Biology, Medical Faculty, University of Milan, Milan, Italy.
Corsi
Massimiliano M
MM
Bonecchi
Raffaella
R
Locati
Massimo
M
Mantovani
Alberto
A
D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D018925:Chemokines / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000276:immunology; D009369:Neoplasms / Q000276:immunology
D000893:Anti-Inflammatory Agents; D018925:Chemokines