Gastrointestinal metastasis of lung cancer with special emphasis on a long-term survivor after operation.
OBJECTIVE
The aim of this study was to report the clinical characteristics and outcomes of gastrointestinal metastasis from lung cancer, with special emphasis on a long-term survivor after surgery.


METHODS
We retrospectively reviewed all patients diagnosed with lung cancer between 2000 and 2007 at a tertiary referral center for cancer.


RESULTS
Gastrointestinal metastases were detected in 10 (0.19%) of 5,239 lung cancer patients. Small bowel metastases occurred in one-half of the patients, making it the most common metastatic site. One patient underwent emergency surgery because of an intestinal perforation. Although a perforation developed only in this patient, surgical intervention was required for five other patients to relieve intestinal obstruction or control bleeding. The prognosis was poor, with a median survival of 96.5 days after diagnosis. However, one patient remains alive >5 years post-operatively, without a recurrence, suggesting that surgical resection is an option for cure in properly selected patients.


CONCLUSIONS
Physicians should be familiar with unique features of lung cancer with metastasis to the gastrointestinal tract so as to render early and optimal management.
Department of Internal Medicine, Korea Cancer Center Hospital, 215-4, Gongneung-dong, Nowon-gu, Seoul, 139-706, South Korea.
Min Soo
MS
Kim
Eun Hee
EH
Kook
Se Han
SH
Ahn
Se Young
SY
Jeon
Jung Ho
JH
Yoon
Min Sung
MS
Han
Cheol Hyeon
CH
Kim
Jae Cheol
JC
Lee
D000368:Aged; D003110:Colonic Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000556:secondary; D006801:Humans; D007414:Intestinal Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology*; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary; D017741:Survivors