[Case of GIST of the rectum successfully treated with imatinib mesylate neoadjuvant therapy].
A 60-year-old man, with a high risk GIST of the rectum, suspected of the infiltration to the prostate and measuring 10 cm in diameter, underwent resection after neoadjuvant therapy of imatinib mesylate. Perineal approach was added because intraperitoneal dissection was not enough, however, the infiltration to the prostate was denied completely due to a reduction in the tumor size, thus total peritoneal resection was avoided. It seems that neoadjuvant therapy with imatinib mesylate is useful for resectability and for the preservation of the functions of ambient organs.
Tsuchida
Kazuhito
K
Department of Gastrointestinal Surgery, Kanagawa Cancer Center.
Shiozawa
Manabu
M
Sugano
Nobuhiro
N
Morinaga
Soichiro
S
Akaike
Makoto
M
Sugimasa
Yukio
Y
Takemiya
Shoji
S
Kameda
Yoichi
Y
Rino
Yasushi
Y
Imada
Toshio
T
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001549:Benzamides; D003082:Colectomy; D046152:Gastrointestinal Stromal Tumors / Q000628:therapy*; D006801:Humans; D000068877:Imatinib Mesylate; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010879:Piperazines / Q000008:administration & dosage*; D011743:Pyrimidines / Q000008:administration & dosage*; D012007:Rectum
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate