Difference in nutritional risk between mild cognitive impairment group and normal cognitive function elderly group.
The purpose of this study was to delineate the difference in nutritional risk between mild cognitive impairment (MCI) groups and normal cognitive function (NCF) elderly groups in the community. Data obtained from 490 subjects (237 NCF elderly and 253 MCI subjects) between 60 and 90 years of age were analyzed. The study protocol comprised demographic characteristics, history of current and past illnesses, drug history, Korean version of short-form Geriatric Depression Scale (K-SGDS), and nutritional screening initiative (NSI) checklist. Cognitive function was assessed by digit span, Korean short version of Boston naming test (K-BNT), simple Rey figure test, auditory verbal learning test (AVLT), controlled oral word association test (COWAT), stroop, go-no go, and contrasting program. Also, we examined the blood pressure, fasting serum glucose level, lipid profile, body mass index (BMI), and ApoE genotype. Multiple logistic regression analysis found that MCI was associated with moderate or high nutritional risk after adjustment for age, sex, educational level, and K-SGDS score (odds ratio (OR)=1.13, 95%; confidence interval (CI)=1.01-1.26). These results suggest that MCI may be associated with nutritional risk. Screening for nutritional risk should be included in multidimensional geriatric evaluation.
Lee
Kang Soo
KS
Department of Psychiatry, Yonsei University College of Medicine, Sungsan-ro 262, Seodaemun-gu, Shinchon-dong, Seoul 120-752, South Korea.
Hong
Chang Hyung
CH
Cheong
Hae-Kwan
HK
Oh
Byoung Hoon
BH
D000368:Aged; D001057:Apolipoproteins E / Q000235:genetics; D015992:Body Mass Index; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009748:Nutrition Disorders / Q000453:epidemiology*; D009752:Nutritional Status; D012307:Risk Factors; D012720:Severity of Illness Index
D001057:Apolipoproteins E