Ibis T5000: a universal biosensor approach for microbiology.
We describe a new technology, the Ibis T5000, for the identification of pathogens in clinical and environmental samples. The Ibis T5000 couples nucleic acid amplification to high-performance electrospray ionization mass spectrometry and base-composition analysis. The system enables the identification and quantification of a broad set of pathogens, including all known bacteria, all major groups of pathogenic fungi and the major families of viruses that cause disease in humans and animals, along with the detection of virulence factors and antibiotic resistance markers.
Ecker
David J
DJ
Ibis Biosciences, 1896 Rutherford Road, Carlsbad, California 92008, USA. decker@ibisbio.com
Sampath
Rangarajan
R
Massire
Christian
C
Blyn
Lawrence B
LB
Hall
Thomas A
TA
Eshoo
Mark W
MW
Hofstadler
Steven A
SA
D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D003140:Communicable Disease Control / Q000379:methods; D021821:Communicable Diseases, Emerging / Q000175:diagnosis* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D006801:Humans; D008828:Microbiological Techniques; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*