Lego clocks: building a clock from parts.
A new finding opens up speculation that the molecular mechanism of circadian clocks in Synechococcus elongatus is composed of multiple oscillator systems (Kitayama and colleagues, this issue, pp. 1513-1521), as has been described in many eukaryotic clock model systems. However, an alternative intepretation is that the pacemaker mechanism-as previously suggested-lies primarily in the rate of ATP hydrolysis by the clock protein KaiC.
Brunner
Michael
M
University of Heidelberg Biochemistry Center, 69120 Heidelberg, Germany. michael.brunner@bzh.uni-heidelberg.de
Simons
Mirre J P
MJ
Merrow
Martha
M
D001426:Bacterial Proteins / Q000502:physiology*; D001683:Biological Clocks; D008954:Models, Biological; D010766:Phosphorylation; D046940:Synechococcus / Q000502:physiology*
D001426:Bacterial Proteins