[HCV genotypes in Polish blood donors in period 1995-2007].
The results of HCV genotype distribution between 1995 and 2007 in Polish blood donors were analyzed. Special attention was drawn into the analysis of HCV polymorphism isolated from blood donors in the early phase of infection (RNA HCV positive/anti-HCV negative). Such donors identified in Poland since 2000 when the NAT for HCV was introduced are very important for molecular epidemiology analysis. The increasing frequency of 3a and 4 genotypes is observed in comparison to blood donors and patients with anti-HCV antibodies.
Brojer
Ewa
E
Zakład Immunologii Hematologicznej i Transfuzjologicznej, Instytut Hematologii i Transfuzjologii, Warszawa. ebrojer@ihit.waw.pl
Grabarczyk
Piotr
P
Kopacz
Aneta
A
Potepa
Anna
A
Medyńska
Joanna
J
Smolarczyk-Wodzyńska
Justyna
J
Letowska
Magdalena
M
D001782:Blood Donors / Q000706:statistics & numerical data*; D005838:Genotype; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D018937:Hepatitis C Antibodies / Q000097:blood*; D018936:Hepatitis C Antigens / Q000097:blood*; D006801:Humans; D008403:Mass Screening / Q000706:statistics & numerical data; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D012367:RNA, Viral / Q000097:blood; D012189:Retrospective Studies
D018937:Hepatitis C Antibodies; D018936:Hepatitis C Antigens; D012367:RNA, Viral