[Venous thromboses and pulmonary arterial thromboembolism in neurosurgical patients].
The paper gives the results of a study conducted in 3 groups of neurosurgical patients in the analysis of autoptic material over 15 years in order to detect pulmonary arterial thromboembolism (PATE) as a cause of postoperative death in neurosurgical patients. In the latter, the incidence of PATE was ascertained to be 5.4%, as evidenced by autopsy and the distribution of the onset of a fatal outcome was biphasic. The informative value of determination of the blood level of fibrin D-dimer was analyzed in neurosurgical patients as a screening method for diagnosing prethrombosis. The method has shown to be of high informative value (about 90% sensitivity) and may be used in clinical practice. The effectiveness and safety of the combined procedure of preventing venous thromboembolic events (mechanical method with a subsequent switching over to pharmacological methods on days 3) were evaluated. The method has proven to be effective and safe.
Markina
M S
MS
Lubnin
A Iu
AIu
Madorskiĭ
S V
SV
Kirichkova
O A
OA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006801:Humans; D048228:Intermittent Pneumatic Compression Devices; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D053828:Stockings, Compression; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control
D000925:Anticoagulants; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D