Sunscreens' photochemical behaviour: in vivo evaluation by the stripping method.
This study shows the influence of a water-in-oil emulsion and an oil-in-water emulsion on the photochemical behaviour of four sunscreen preparations containing various amounts of three UV filters: octyl methoxycinnamate, butyl methoxydibenzoylmethane, and 4-methylbenzylidene camphor. With the stripping method in vivo, skin-product interactions were evaluated after topical application and ultra-violet exposure. Evaluations were also made under the same operating conditions as in determining sun protection factor in vivo. Results showed that each sunscreen preparation has a particular photochemical behaviour related to filter mixture and emulsion type. When developing a sunscreen preparation the choice of the emulsion type and filters is relevant for achieving optimum efficacy and spectral stability.
Laboratoires Lutsia, 17 rue de Pontoise, 95521 Osny Cedex France.
G
G
Marginean Lazar
A E
AE
Fructus
A
A
Baillet
J L
JL
Bocquet
P
P
Thomas
J P
JP
Marty