Predictors of restenosis after coronary artery stenting.
OBJECTIVE
The aim of this study was to analyze restenosis after percutaneous coronary intervention, factors related to restenosis after coronary artery stenting and the degree of the risk of restenosis were evaluated.


METHODS
The study enrolled 181 patients (249 lesions) who underwent the first coronary artery stenting. Multivariate analysis was performed, and the restenotic index (RI) was calculated by combining the extracted predictors.


RESULTS
Among the 181 patients (249 lesions), restenosis occurred in 89 (111 lesions) and did not occur in 92 (138 lesions). Vascular revasculation was performed in 95 restenosed target lesions in 68 patients. The mean period of follow-up angiography after the procedures was 206 days in the restenosis group and 271 days in the non-restenosis group, i.e. significantly shorter in the restenosis group. As a result of multivariate analysis, diabetes mellitus, Cr level, amount of the contrast medium used and stent diameter were selected as significant factors that independently contributed to the restenosis after coronary artery stenting. By combining these factors, the RI was calculated by the following formula for the prediction of restenosis: RI=exp (1.088xCr+0.909xdiabetes mellitus+0.871xcontrast medium+0.591xstent diameter).


CONCLUSIONS
The risk of restenosis after coronary artery stenting can be predicted to an extent according to the RI devised in this study.
Health Service Center, Showa University, Tokyo, Japan. yoneyama@med.showa-u.ac.jp
K
K
Yoneyama
A
A
Tsuboya
M
M
Kogo
Y
Y
Kiuchi
Y
Y
Takeyama
D000368:Aged; D017023:Coronary Angiography; D005260:Female; D006083:Graft Occlusion, Vascular / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment; D015607:Stents