[Rare concurrence of airway scleroma and nonspecific aortoarteritis (Takayasu's disease)].
A case of a rare concomitance of airway scleroma and nonspecific aortoarteritis was studied in a 14-year-old girl, a native from the scleroma endemic Rovno Region. She had been treated for 4 years for this disease verified by a histological study of a laryngeal biopsy specimen. The fact that scleroma was a predictor of Takayasu's disease in this case cannot be ruled out; suggesting a pathogenetic association between both diseases. Concentric narrowing of the lumen of the aorta and its branching vessels contributed to the development of hypoxia and CNS ischemia, which worsened the severity of a pathological process in the airway and caused a fatal outcome during an episode of asphyxia.
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Iampol'skaia
D000293:Adolescent; D001011:Aorta / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007830:Larynx / Q000473:pathology; D012226:Rhinoscleroma / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D013625:Takayasu Arteritis / Q000150:complications* / Q000473:pathology* / Q000628:therapy