Interplay of JH, 20E and biogenic amines under normal and stress conditions and its effect on reproduction.
Juvenile hormone (JH) and 20-hydroxyecdysone (20E) are well known to play a gonadotropic role in adult insects. In Drosophila the mechanism of reciprocal regulation of JH and 20E is shown to be responsible for their proper balance. Dopamine is a mediator in this JH and 20E interplay. A proper balance between JH and 20E is crucial for the normal progress of oogenesis. An imbalance of gonadotropins leads to reproductive defects: a rise in JH titre leads to oviposition arrest, a rise in 20E level, to the degradation of vitellogenic oocytes. Upon a change in the level of one of the gonadotropins, the balance is restored owing to the relative change in the titre of the other.
Gruntenko
N E
NE
Laboratory of Stress Genetics, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Lavrentjev ave. 10, 630090 Novosibirsk, Russia. nataly@bionet.nsc.ru
Rauschenbach
I Yu
IY
D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000502:physiology*; D004441:Ecdysterone / Q000378:metabolism*; D005260:Female; D007605:Juvenile Hormones / Q000378:metabolism*; D052287:Oviparity
D015306:Biogenic Monoamines; D007605:Juvenile Hormones; D004441:Ecdysterone