Evaluation of bone mass in children with long bone fracture compared with controls.
Childhood is a critical period for achieving skeletal mass. In adults, low bone density is associated with an increased fracture risk and it has been postulated that the same is true for children. If this were the case, we would expect that children with fractures might have a lower bone mass than those without. A case-control study of 30 cases and 30 age and sex-matched controls was carried out. Each child underwent height and weight measurements, a simple interview and phalangeal ultrasound to measure speed of sound. The difference in mean speed of sound was -51.81 m/s (95% confidence interval -83.0 to -20.6; P=0.002) in children with simple long bone fractures versus controls. In children, there appears to be a significant difference in bone mass between those with a simple long bone fracture and those who have never sustained a fracture. To be certain that this is owing to cause rather than effect, and also as this is an important public health issue, further studies are warranted.
Bradshaw
Joanne H
JH
Department of Paediatrics, The General Infirmary at Leeds, Leeds, UK. jo.bradshaw@cht.nhs.uk
Holland
Philip
P
Feltbower
Richard G
RG
D015502:Absorptiometry, Photon; D000293:Adolescent; D015519:Bone Density / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D050278:Finger Phalanges / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D006810:Humeral Fractures / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D008297:Male; D011885:Radius Fractures / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D015599:Trauma Severity Indices; D014463:Ultrasonography; D006113:United Kingdom / Q000453:epidemiology