Calciphylaxis of the breast: a rare disease in the differential diagnosis of breast cancer.
Calciphylaxis is a rare, but potentially life-threatening condition usually observed in patients with end-stage chronic renal disease and characterized by small- and medium-sized blood vessel calcification leading to tissue ischemia. The clinical features are primarily cutaneous, consisting of skin necrosis and ulceration, mostly located in the lower extremities. We report a case of a 56-year-old woman with a previous history of renal disease and atypical lobular hyperplasia of the right breast, who developed painful skin necrosis on both breasts. Differential diagnosis comprises acute bacterial infection with ulceration, cutaneous vasculitis, cancer and calciphylaxis.
Padovan
Cristina
C
UCO di Dermatologia, Dipartimento di Scienze Cliniche Morfologiche e Tecnologiche, Università di Trieste Ospedale Maggiore - Palazzina infettivi, Via Pietà, 34100 Trieste, Italy. c_padovan@inwind.it
Bonfigli
Fabrizio
F
Ulessi
Bruno
B
Gottardi
Chiara
C
Giansante
Carlo
C
Trevisan
Giusto
G
D001941:Breast Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D001943:Breast Neoplasms; D002115:Calciphylaxis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D000069449:Cinacalcet; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008408:Mastectomy; D008875:Middle Aged; D009281:Naphthalenes / Q000008:administration & dosage; D016105:Parathyroidectomy; D016896:Treatment Outcome
D009281:Naphthalenes; D000069449:Cinacalcet