[A comparative study of sphingolipids in transplanted melanomas with high and low metastatic activity].
The content of sphingolipids in M3 and B16/F10 melanomas with a high metastatic potential and in Claudman's and B16/F1 melanomas with a low metastatic potential was studied. It was shown that the content of total lipid-bound sialic acids and ganglioside GM3 in melanomas with a high metastatic potential is considerably higher than that in melanomas with a low metastatic potential. On the other hand, the ceramide to glucosylceramide molar ratio is higher in melanomas with a low metastatic potential. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2008, vol. 34, no. 2; see also http://www.maik.ru.
Kandyba
A G
AG
Kozlov
A M
AM
Somova
O G
OG
Diatlovitskaia
E V
EV
D000818:Animals; D008546:Melanoma, Experimental / Q000378:metabolism* / Q000556:secondary*; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009368:Neoplasm Transplantation; D013107:Sphingolipids / Q000378:metabolism*
D013107:Sphingolipids