Successful topical treatment with mitomycin-C in a female with post-brachytherapy vaginal stricture.
Vaginal strictures are rare entities in pediatric population, mainly due to congenital genito-urinary tract malformations and sequelae of their surgical treatment, recurrent vaginitis and multisciplinary therapy for malignant tumors. The therapy of choice is not standardized. Conservative treatments are favored and dilators seem to be very effective, but their use in children is difficult due to poor compliance. We report our experience with topical application of mitomycin-C in a female with vaginal stricture secondary to brachytherapy.
Pediatric Surgery Unit, Department of Pediatrics, University Hospital, Padova, Italy.
Pietro
P
Betalli
Federica
F
De Corti
Daria
D
Minucci
Renzo
R
Mazzarotto
Luisa
L
Meneghini
Gianni
G
Bisogno
Giovanni
G
Cecchetto
D000293:Adolescent; D001918:Brachytherapy / Q000009:adverse effects*; D003251:Constriction, Pathologic / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D016685:Mitomycin / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000150:complications / Q000188:drug therapy; D014625:Vaginal Neoplasms / Q000150:complications* / Q000188:drug therapy* / Q000532:radiotherapy
D016685:Mitomycin