Interplay of JH, 20E and biogenic amines under normal and stress conditions and its effect on reproduction.
Juvenile hormone (JH) and 20-hydroxyecdysone (20E) are well known to play a gonadotropic role in adult insects. In Drosophila the mechanism of reciprocal regulation of JH and 20E is shown to be responsible for their proper balance. Dopamine is a mediator in this JH and 20E interplay. A proper balance between JH and 20E is crucial for the normal progress of oogenesis. An imbalance of gonadotropins leads to reproductive defects: a rise in JH titre leads to oviposition arrest, a rise in 20E level, to the degradation of vitellogenic oocytes. Upon a change in the level of one of the gonadotropins, the balance is restored owing to the relative change in the titre of the other.
Laboratory of Stress Genetics, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Lavrentjev ave. 10, 630090 Novosibirsk, Russia. nataly@bionet.nsc.ru
N E
NE
Gruntenko
I Yu
IY
Rauschenbach
D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000502:physiology*; D004441:Ecdysterone / Q000378:metabolism*; D005260:Female; D007605:Juvenile Hormones / Q000378:metabolism*; D052287:Oviparity
D015306:Biogenic Monoamines; D007605:Juvenile Hormones; D004441:Ecdysterone