Chemical composition and antispasmodic effect of Casimiroa pringlei essential oil on rat uterus.
The Casimiroa pringlei essential oil was analyzed to determine its chemical composition. Its effect on rat uterine smooth muscle was studied and compared with verapamil. Pure commercial piperitone, eucalyptol, and alpha-terpineol, the major constituents of C. pringlei essential oil, were tested on the uterine tonic contraction induced by high-potassium depolarizing solution (KCl 60 mM).
Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Mexico. Hecpon43@yahoo.com.mx
Héctor
H
Ponce-Monter
María G
MG
Campos
Salud
S
Pérez
Cuauhtémoc
C
Pérez
Miguel
M
Zavala
Arturo
A
Macías
Martha
M
Oropeza
Norma
N
Cárdenas
D000704:Analysis of Variance; D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology; D032081:Casimiroa / Q000737:chemistry; D002849:Chromatography, Gas; D005260:Female; D013058:Mass Spectrometry; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010276:Parasympatholytics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts; D010938:Plant Oils / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D014590:Uterine Contraction / Q000187:drug effects*; D014599:Uterus / Q000187:drug effects*; D014700:Verapamil / Q000494:pharmacology
D002121:Calcium Channel Blockers; D009822:Oils, Volatile; D010276:Parasympatholytics; D010936:Plant Extracts; D010938:Plant Oils; D011189:Potassium Chloride; D014700:Verapamil