Lipodystrophia centrifugalis abdominalis infantilis in a Caucasian girl: report of a case with perieccrine inflammation.
Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is a rare, self-limiting disease typically affecting Asian children around the age of three. In classic cases, patients present with a hypopigmented patch with central atrophy and an erythematous border in the groin area. We present a case of LCAI affecting a female Caucasian toddler that shows striking perieccrine inflammation, a finding not previously reported in this entity. LCAI has been rarely reported in Caucasian children; as a result, there is sparse literature on the histopathological findings in this subset. This case illustrates how significant deep dermal and perieccrine inflammation can be seen in this condition, thus broadening the histopathological spectrum of this disorder.
Department of Dermatology, University of Utah, Salt Lake City, UT 84132, USA.
Hege Grande
HG
Sarpa
Sheryll
S
Vanderhooft
Anneli R
AR
Bowen
D002675:Child, Preschool; D003879:Dermatologic Agents; D004439:Eccrine Glands / Q000473:pathology*; D005260:Female; D006119:Groin / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000188:drug therapy / Q000473:pathology*; D008060:Lipodystrophy / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000627:therapeutic use; D044465:White People
D003879:Dermatologic Agents; C117268:pimecrolimus; D016559:Tacrolimus