Autologous chondrocyte implantation: where do we stand now?
Chondral damage to the young knee is common. In symptomatic patients current surgical treatment has focused on filling the defect with fibrocartilage; however, this tissue has poor resistance to shear forces, leading to failure and the onset of degenerative osteoarthritis.
Gikas
P D
PD
Bone Tumour Unit and Joint Reconstruction Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, UK.
Aston
W J S
WJ
Briggs
T W R
TW
D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000628:therapy*; D002358:Cartilage, Articular / Q000293:injuries* / Q000502:physiology / Q000637:transplantation; D019902:Chondrocytes / Q000637:transplantation*; D020219:Chondrogenesis / Q000502:physiology; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014182:Transplantation, Autologous