Selective cauda equina hypertrophy with idiopathic inflammation.
A 20-year-old woman with selective cauda equina hypertrophy presented with muscle weakness and severe pain in the lower extremities. Serial immunotherapy was not effective. We performed biopsy of the cauda equina, and laminectomy and duraplasty of the thoracolumbar region. Biopsy revealed marked infiltration of small lymphocytes and foamy macrophages in the endoneurium. Three years after decompression surgery, her symptoms have improved slightly without progression or relapse. This is the first case of selective cauda equina hypertrophy with idiopathic inflammation. We propose that this is a new disease entity.
Hayashi
Yuichi
Y
Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Japan. hayashiy@gifu-u.ac.jp
Sakurai
Takeo
T
Kimura
Akio
A
Ikeda
Takahide
T
Matsuyama
Zenjiro
Z
Suzuki
Yoshihiro
Y
Tanaka
Yuji
Y
Hozumi
Isao
I
Hosoe
Hideo
H
Takahashi
Hitoshi
H
Inuzuka
Takashi
T
D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009220:Myositis / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D011128:Polyradiculopathy / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D019788:Fluorodeoxyglucose F18; C067980:CD68 antigen, human; D000097382:CD68 Molecule