Improvement of Lactobacillus plantarum aerobic growth as directed by comprehensive transcriptome analysis.
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that resumption of growth after stagnation correlated with activation of CO(2)-producing pathways, suggesting that a limiting CO(2) concentration induced the stagnation. Analogously, increasing the CO(2) gas partial pressure during aerobic fermentation prevented the temporal growth stagnation.
TI Food and Nutrition, P.O. Box 557, 6700 AN Wageningen, The Netherlands.
Marc J A
MJ
Stevens
Anne
A
Wiersma
Willem M
WM
de Vos
Oscar P
OP
Kuipers
Eddy J
EJ
Smid
Douwe
D
Molenaar
Michiel
M
Kleerebezem
D000332:Aerobiosis; D000693:Anaerobiosis; D002245:Carbon Dioxide / Q000378:metabolism; D005285:Fermentation; D020869:Gene Expression Profiling; D007700:Kinetics; D048191:Lactiplantibacillus plantarum / Q000235:genetics* / Q000254:growth & development*; D014158:Transcription, Genetic
D002245:Carbon Dioxide