Oxidative rearrangements of isobenzofurans: studies toward the synthesis of the ajudazols.
We present a new facet of isobenzofuran chemistry which allows for its efficient manipulation to generate biologically relevant entities. This methodology has been successfully applied toward the synthesis of ajudazol A.
WestCHEM, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
Stephen J
SJ
Hobson
Andrew
A
Parkin
Rodolfo
R
Marquez
D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism; D001572:Benzofurans / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction
D001572:Benzofurans; D001688:Biological Products; D003374:Coumarins; C105430:benzofuran