Skeletal muscle and bone: effect of sex steroids and aging.
Both estrogen and testosterone are present in males and females. Both hormones contribute to the well being of skeletal muscle and bone in men and women, and there is evidence that the loss of sex hormones is associated with the age-related decline in bone and skeletal muscle mass. Hormonal supplementation of older adults to restore estrogen and testosterone levels to those of young men and women is not without penalty.
Brown
Marybeth
M
Center for Gender Physiology, Physical Therapy Program, Biomedical Sciences, University of Missouri, Columbia, Missouri 65211, USA. brownmb@health.missouri.edu
D000375:Aging / Q000502:physiology*; D001846:Bone Development / Q000502:physiology*; D001842:Bone and Bones / Q000502:physiology*; D004967:Estrogens / Q000502:physiology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D008297:Male; D008593:Menopause; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000254:growth & development / Q000502:physiology*; D013718:Tensile Strength / Q000502:physiology; D013739:Testosterone / Q000502:physiology
D004967:Estrogens; D012739:Gonadal Steroid Hormones; D013739:Testosterone