Sexual precocity associated with an abdominal tumor in an African boy.
We report a 3 year-old boy in Tanzania with an abdominal mass and isosexual precocity due to an hCG-secreting hepatoblastoma. Due to the limited availability of local diagnostic testing, surgery and chemotherapy were completed before immunohistochemical and endocrine results were available.
School of Paediatrics, University of NSW, Sydney, Australia. henningb2004@yahoo.com
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Bode
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Schimana
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Swai
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D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006498:Hepatectomy; D018197:Hepatoblastoma / Q000097:blood / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology*; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000032:analysis; D051176:beta Catenin / Q000097:blood
D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D051176:beta Catenin; D005047:Etoposide; D002945:Cisplatin