Recently published papers: a little less ventilation, a little more oxygen please?
Recent papers discussed include two large, multicentre, high-positive end-expiratory pressure trials in acute lung injury and reflects upon the usefulness of such trial designs. Further papers considered include the emerging story of beta2-agonists for pulmonary oedema, highlights the newly described, iatrogenic demon, of ventilator-induced diaphragm injury, promotes the addition of B-type natriuretic peptide testing to the prediction of extubation success, and muses again over the oxygen debate.
General Intensive Care Unit, St George's Hospital, London SW17 0QT, UK. jball@sgul.ac.uk
Jonathan
J
Ball
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000818:Animals; D016638:Critical Illness; D003964:Diaphragm / Q000473:pathology; D006801:Humans; D018496:Hyperoxia; D009133:Muscular Atrophy / Q000209:etiology; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010102:Oxygen Inhalation Therapy; D011175:Positive-Pressure Respiration / Q000379:methods; D011654:Pulmonary Edema / Q000188:drug therapy; D016032:Randomized Controlled Trials as Topic; D012121:Respiration, Artificial / Q000009:adverse effects; D012128:Respiratory Distress Syndrome / Q000628:therapy; D018805:Sepsis / Q000628:therapy; D015300:Ventilator Weaning
D000318:Adrenergic beta-Agonists; D020097:Natriuretic Peptide, Brain