Susceptibility testing and molecular classification of Paecilomyces spp.
In vitro susceptibility profiles of 58 Paecilomyces clinical isolates are reported. Amphotericin B, itraconazole, and echinocandins showed poor activity against Paecilomyces lilacinus, while the new triazoles were active against it. Paecilomyces variotii exhibited a different susceptibility pattern, being susceptible to most antifungal agents apart from voriconazole and ravuconazole.
Servicio de Micologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Carretera Majadahonda-Pozuelo Km2, 28220 Majadahonda, Madrid, Spain.
Maria Victoria
MV
Castelli
Ana
A
Alastruey-Izquierdo
Isabel
I
Cuesta
Araceli
A
Monzon
Emilia
E
Mellado
Juan L
JL
Rodriguez-Tudela
Manuel
M
Cuenca-Estrella
D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D004271:DNA, Fungal / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D054714:Echinocandins / Q000494:pharmacology; D017964:Itraconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010143:Paecilomyces / Q000145:classification / Q000187:drug effects* / Q000235:genetics*; D010802:Phylogeny
D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D054714:Echinocandins; D017964:Itraconazole; D000666:Amphotericin B