Chiral phosphites derived from carboranes: electronic effect in catalytic asymmetric hydrogenation.
A series of new fine-tunable monodentate phosphite and phosphoramidite ligands based on carboranes have been synthesized and used for asymmetric Rh-catalyzed hydrogenation of prochiral olefins with the result of up to 99.8% ee. Dependence of the enantioselectivity on the electron-withdrawing or electron-donating properties of the carboranyl substituent has been studied.
Lyubimov
Sergey E
SE
Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia. lssp452@mail.ru
Kalinin
Valery N
VN
Tyutyunov
Andrey A
AA
Olshevskaya
Valentina A
VA
Dutikova
Yulia V
YV
Cheong
Chan Seong
CS
Petrovskii
Pavel V
PV
Safronov
Anton S
AS
Davankov
Vadim A
VA