Listeria monocytogenes meningitis associated with rhabdomyolysis and acute renal failure.
BACKGROUND
Numerous systemic infections are capable of inducing myositis and rhabdomyolysis. Clinical course of the disease is in the great majority of patients benign and without development of renal dysfunction. However, serious consequences are possible if acute renal failure (ARF) occurs, especially in critically ill patients.


METHODS
Patient with Listeria monocytogenes meningitis associated with rhabdomyolysis and acute non-oliguric ARF is presented.


RESULTS
Sixty-nine-year-old white male was admitted to our intensive care unit because of listerial meningitis. The course of the disease was complicated with rhabdomyolysis and non-oliguric ARF. After antimicrobial treatment with parenteral trimethoprim-sulfamethoxazole and 4 days of continuous veno-venous hemodiafiltration (CVVHDF) the patient recovered.


CONCLUSIONS
We report a case of listerial meningitis complicated with non-oliguric ARF. Rhabdomyolysis should be considered in all patients with infection and increased CK, especially if consciousness is impaired is altered. Furthermore, despite the normal diuresis ARF could be present and result in adverse consequences. We infer that timely diagnosis and treatment should improve the outcome of infection-induced rhabdomyolysis and could prevent a proportion of associated ARF.
Kutlesa
Marko
M
Department of Neuroinfections and Intensive Care Medicine, University Hospital for Infectious Diseases, Mirogojska 8, 10000, Zagreb, Croatia. kutlesam@yahoo.com
Lepur
Dragan
D
Bukovski
Suzana
S
Lepur
Nevija Kalabrić
NK
Barsić
Bruno
B
D058186:Acute Kidney Injury / Q000382:microbiology*; D000368:Aged; D006801:Humans; D008297:Male; D008584:Meningitis, Listeria / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D012206:Rhabdomyolysis / Q000382:microbiology*