A silencing safeguard: links between RNA silencing and mRNA processing in Arabidopsis.
RNA silencing is a genome defense mechanism used by many eukaryotic organisms to fight viruses and to control transposable elements. Work by Gregory et al. on Arabidopsis thaliana (in this issue of Developmental Cell) revealed a mechanism whereby the plant protects its endogenous messenger RNAs from undergoing RNA silencing and uncovered an unexpected role of the cap-binding protein ABH1 in miRNA biogenesis.
Chen
Xuemei
X
Department of Botany and Plant Sciences, University of California, Riverside, Riverside, CA 92521, USA. xuemei.chen@ucr.edu
D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000235:genetics / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism; D005095:Exoribonucleases / Q000235:genetics / Q000378:metabolism; D020868:Gene Silencing; D017343:Genes, Plant; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D039381:RNA Cap-Binding Proteins / Q000235:genetics / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000378:metabolism*; D018749:RNA, Plant / Q000235:genetics / Q000378:metabolism; D034741:RNA, Small Interfering / Q000737:chemistry / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics / Q000378:metabolism; D043244:Ribonuclease III / Q000235:genetics / Q000378:metabolism; D000072099:Serrate-Jagged Proteins
D029681:Arabidopsis Proteins; D002135:Calcium-Binding Proteins; D018797:Cell Cycle Proteins; D005095:Exoribonucleases; D036341:Intercellular Signaling Peptides and Proteins; D008565:Membrane Proteins; D035683:MicroRNAs; D010940:Plant Proteins; D039381:RNA Cap-Binding Proteins; D012333:RNA, Messenger; D018749:RNA, Plant; D034741:RNA, Small Interfering; D016601:RNA-Binding Proteins; D012324:RNA-Dependent RNA Polymerase; D043244:Ribonuclease III; D000072099:Serrate-Jagged Proteins; C435105:At2g13540 protein, Arabidopsis; C420966:HYL1 protein, Arabidopsis; C000606277:SE protein, Arabidopsis; C418137:Xrn1 protein, plant; C514575:RDR6 protein, Arabidopsis; C402383:DCL1 protein, Arabidopsis