One-step multicomponent encapsulation by compound-fluidic electrospray.
Fabrication of sophisticated or smart materials often needs controlled integrating multiple components into a single capsule. Most of conventional microencapsulation strategies merely envelop one content into a shell every time. We report a compound-fluidic electrospray method could one-step enclose multiple components into a single microcapsule without contact. The as-prepared microcapsules have multiple compartments inside, in each of which different content can be addressably loaded. This approach gives flexibility for generating diverse microcapsules that could one-step integrate different active components in microscopic domain free of contact, which may find potential applications in multicomponent drug delivery, microreactors and others.
Chen
Hongyan
H
Beijing National Laboratory for Molecular Sciences, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, PR China.
Zhao
Yong
Y
Song
Yanlin
Y
Jiang
Lei
L
D004339:Drug Compounding / Q000295:instrumentation* / Q000379:methods*; D005456:Fluorescent Dyes / Q000737:chemistry; D005990:Glycerol / Q000737:chemistry; D008863:Microspheres; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D014025:Titanium / Q000737:chemistry
D005456:Fluorescent Dyes; D011108:Polymers; C009495:titanium dioxide; D014025:Titanium; D005990:Glycerol