Assessment of exercise capacity in women with type 2 diabetes.
The primary aim of this study was to compare the maximal oxygen uptake as evaluated from a submaximal exercise test (EVO2peak) to direct measurements of VO2peak during a maximal exercise test as means of monitoring the aerobic endurance capacity in women with type 2 diabetes (T2D). Twenty-seven women with T2D participated in the study. The program consisted of combined group training 1 h twice a week during 12 weeks and walks 1 h per week. EVO2 max was estimated using a submaximal exercise test on a bicycle ergometer ad modum Astrand. VO2peak and maximal work rate were measured using an incremental maximal exercise test on an electrically braked bicycle ergometer at baseline and after 6 and 12 weeks. EVO2peak was higher than VO2peak at baseline and significantly higher at 12 weeks (EVO2peak1.92+/-0.54 l min(-1), VO2peak 1.41+/-0.36, P<0.005). Maximal work rate increased significantly after 12 weeks (12+/-15, P<0.005) compared to baseline. The main finding of this study was that EVO2peak assessed using a submaximal exercise test, systematically overestimated VO2peak. The combined group training increased maximal work rate but not VO2peak. This is likely to reflect peripheral adaptation to exercise and/or improved mechanical efficiency.
Segerström
Asa B
AB
Division of Physiotherapy, Department of Health Sciences, Lund University, Lund, Sweden. asa.segerstrom@med.lu.se
Glans
Forouzan
F
Eriksson
Karl-Fredrik
KF
Groop
Leif
L
Thorsson
Ola
O
Wollmer
Per
P
D000222:Adaptation, Physiological / Q000502:physiology; D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism* / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D010807:Physical Endurance / Q000502:physiology*