Haemostasis after cold-knife conisation: a randomised prospective trial comparing cerclage suture versus electro-cauterization.
OBJECTIVE
The purpose of this study was to compare two different techniques of obtaining haemostasis after cold-knife conisation.


METHODS
Seventy-eight women who required conisation for treatment of cervical intraepithelial neoplasia were prospectively enrolled in a randomised clinical trial to receive either cerclage with cold-knife conisation or cautery with cold-knife conisation. Outcome measures evaluated include estimated blood loss, operative time, early late haemorrhage and dysmenorrhoea. The short- and long-term morbidity was compared, and a six-month follow up was completed.


RESULTS
The procedure-related complication rate was 16.7% in the cautery group, compared with 7.0% in the suture group (P < 0.05). The cerclage group had significantly shorter operative time and intraoperative blood loss than the cautery group (P < 0.05). Postoperative bleeding and dysmenorrhoea were observed in eight (10.2%), and 14 cases (17.9%), in cerclage and cautery group, respectively. Three cases (3.8%) had postoperative infections and were cured with oral antibiotics.


CONCLUSIONS
These results suggest that cerclage suturing technique provided excellent haemostasis and restoration of normal cervical anatomy. Cerclage suture of the cone bed is superior to only cauterization as a method of achieving haemostasis, with significantly less blood loss and shorter operative time.
Dane
Cem
C
Department of Gynecology and Obstetrics, Haseki Training and Research Hospital, Istanbul, Turkey. cemdane@yahoo.com
Dane
Banu
B
Cetin
Ahmet
A
Erginbas
Murat
M
D000328:Adult; D023802:Cerclage, Cervical; D002584:Cervix Uteri / Q000601:surgery; D019092:Conization / Q000009:adverse effects* / Q000379:methods; D004564:Electrocoagulation; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000601:surgery*