[Systane and cataract surgery].
OBJECTIVE
To emphasize and measure the effect of post-cataract surgery Systane treatment.


METHODS
Eye Clinic - Central Clinical Hospital - Bucharest, Romania.


METHODS
Six months clinical, observational, prospective, double-masked study on two groups of patients with cataract surgery (phacoemulsification technique) performed by the same surgeon. Group A (19 patients) received topic treatment with Systane and group B (17 patients) topic treatment with purified water (both with the same presentation form), associated with classical postoperatively treatment. Each patient answered a standardized questionnaire about subjective symptoms of ocular discomfort Several clinical tests were performed for both groups: Schirmer 1 test, tear break-up time (TBUT) and fluorescein staining showing epithelial defects. The groups were homogeneous about the age and sex distribution.


METHODS
any ocular or general associated disease. Statistic analyse: t-student test.


RESULTS
First examination (after one week treatment) show that 73,68% patients treated with Systane did not have subjective symptoms comparing with 47,05% patients without Systane. Final tests (3 week examination) results for subjective symptoms were improved in both groups: 94,73% group A and 70,58% group B (p<0,001). Abnormal values (under 10 mm) for Schirmer 1 test were found in 17,64% of group B patients comparing with 11,76% patients of group A at the first examination. Final Schirmer 1 test results are statistically better in group A 100%-normal values, comparing with 88,23%-normal values in group B. The stability of tear film (TBUT) is altered in 52,94% of purified water treated patients; only in 21,05% of Systane patients existing this problem at the first examination (p<0,001). After 3 weeks treatment 23,52% group B patients and 5,26% group A patients had TBUT altered. Initially fluorescein staining is present in 4 group B patients and in 1 group A patient, comparing with only 1 group B patient in final tests.


CONCLUSIONS
Cataract surgery can affect ocular tear film production and stability by many factors including postoperatively anti-inflammatory classical treatment. Systane prevents the signs and symptoms of tear film insufficiency, decrease post surgery complications and improve epithelial repair. Systane gives a higher satisfaction to the patient associated with a healthy and stable ocular surface.
Stefan
C
C
Central Clinical Military Hospital, Bucharest, Romania. cstefan58@yahoo.com
Dumitrica
Diana Melinte
DM
D000368:Aged; D002387:Cataract Extraction; D004311:Double-Blind Method; D015352:Dry Eye Syndromes / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage* / Q000737:chemistry; D018918:Phacoemulsification / Q000379:methods; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013666:Tears / Q000187:drug effects*; D016896:Treatment Outcome
D009883:Ophthalmic Solutions