[Case report: periodical infliximab administration enabled closure of colostomy in fistulating perianal Crohn's disease].
A 29-year old woman with Crohn's disease was performed colostomy due to severe perianal abscess. Her disease had been easy to recur and she was admitted to hospital for intestinal bleeding caused by acute exacerbation in Crohn's disease on October 2006. The bleeding was stopped rapidly and clinical remission was maintained with bimonthly administration of infliximab. Finally, her colostomy was closed after 5 years 8 months. Periodical treatment of infliximab not only prevented recurrence but also enabled closure of colostomy in fistulating perianal Crohn's disease.
Department of Internal Medicine, Shiga University of Medical Science.
Tomoyuki
T
Tsujikawa
Hirotsugu
H
Imaeda
Yu
Y
Kobayashi
Rie
R
Oosaki
Ayano
A
Sonoda
Kumiko
K
Senou
Kiyoyuki
K
Hayafuji
Hideki
H
Minematsu
Atsuhiro
A
Ogawa
Tamio
T
Nakahara
Kazunori
K
Hata
Akira
A
Andoh
Masaya
M
Sasaki
Yasuharu
Y
Saito
Yoshihide
Y
Fujiyama
D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D003125:Colostomy; D003424:Crohn Disease / Q000628:therapy*; D005260:Female; D005765:Gastrointestinal Agents / Q000008:administration & dosage*; D006801:Humans; D000069285:Infliximab; D012074:Remission Induction; D055502:Secondary Prevention; D016896:Treatment Outcome
D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D000069285:Infliximab