Thymoma, myasthenia gravis, and other paraneoplastic syndromes.
The relationship between myasthenia gravis and thymic pathology, including thymoma, is well known. Approximately 10% to 15% of patients who have myasthenia gravis are observed to have a thymoma. Myasthenia gravis may be considered as the most common of the paraneoplastic syndromes in patients who have thymoma. This article summarizes the clinical aspects of myasthenia gravis, followed by a review of the less often recognized paraneoplastic disorders noted to occur in patients who have thymoma.
Tormoehlen
Laura M
LM
Department of Neurology, Indiana University School of Medicine, Emerson Hall Room 125, 545 Barnhill Drive, Indianapolis, IN 46202, USA. laumjone@iupui.edu
Pascuzzi
Robert M
RM
D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents; D009157:Myasthenia Gravis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D010257:Paraneoplastic Syndromes / Q000150:complications*; D013934:Thymectomy / Q000009:adverse effects; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*
D002800:Cholinesterase Inhibitors; D007166:Immunosuppressive Agents