[Comparison of fundus photography and fluorescein angiography in grading diabetic retinopathy].
OBJECTIVE
To study the consistency of the color fundus photography and fluorescein angiography for grading the diabetic retinopathy.


METHODS
It was a retrospective case series. The agreement study was conducted in a series of diabetic patients, who were excluded from the mild non-proliferative diabetic retinopathy (NPDR) and the severe proliferative diabetic retinopathy (PDR). Ninety-nine cases (188 eyes) met the selected criteria Five 50 degrees non-stereoscopic photography for each eye were taken in all cases before FFA was performed. The diabetic retinopathy was graded from the fundus photography and FFA images according to international diabetic retinopathy disease severity scale. The kappa value was calculated according to the grading outcomes from the fundus photography and FFA images to estimate the agreement of the grading outcomes.


RESULTS
The fundus photography showed 59 moderate NPDR (31.4%), 76 severe NPDR (40.4%) and 53 PDR eyes (28.2%) respectively, FFA showed 50 moderate NPDR (26.6%), 72 severe NPDR (38.3%) and 66 PDR (35.1%) respectively. The agreement for the grading of DR by the fundus photography and FFA was substantial (K = 0.601). In the evaluation whether it was necessary to implement PRP (more serious than NPDR and PDR), there was higher agreement between them (K = 0.652).


CONCLUSIONS
Five 50 degrees photography can provides the support of the application of PRP for diabetic patients, FFA may be earlier and relatively accuracy in the diagnose of diabetic retinopathy.
Beijing Tongren Eye Center, Beijing Tongren Hospital Affiliated of Capital Medical University, Beijing 100730, China.
Li-qin
LQ
Gao
Feng
F
Zhang
Hai-ying
HY
Zhou
Wei
W
Yan
Ying
Y
Xiong
Guang-lu
GL
Wang
D000328:Adult; D000368:Aged; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010781:Photography; D011859:Radiography; D012189:Retrospective Studies; D012720:Severity of Illness Index