Long-range correlation of renal sympathetic nerve activity in both conscious and anesthetized rats.
In this study we employed both detrended fluctuation analysis (DFA) and multiscale entropy (MSE) measurements to compare the long-range temporal correlation (LRTC) of multifibre renal sympathetic nerve activity (RSNA) between conscious and anesthetized Wistar rats. It was found that both methods showed the obvious LRTC properties in conscious state. Moreover, the scaling exponent of the RSNA in conscious rats was significantly higher than that in anesthetized rats. The results of MSE analysis showed that the entropy values, derived from the conscious group, increased on small time scales and then stabilized to a relatively constant value whereas the entropy measure, derived from anesthetized animals, almost monotonically decreased. This suggests that the fractal properties of underlying dynamics of the system have been reduced by anesthesia. The results demonstrate that apparently random fluctuations in multifibre RSNA are dictated by a complex deterministic process that imparts "long-term" memory to the dynamic system. However, this memory is significantly weakened by anesthesia.
Key Laboratory of Bioactive Materials, Ministry of Education and the College of Life Sciences, Nankai University, Tianjin 300071, PR China.
Yatang
Y
Li
Jiaheng
J
Qiu
Zhuo
Z
Yang
Edward J
EJ
Johns
Tao
T
Zhang
D000200:Action Potentials / Q000502:physiology; D000758:Anesthesia; D000818:Animals; D003243:Consciousness / Q000502:physiology*; D019277:Entropy; D017709:Fractals; D007668:Kidney / Q000294:innervation*; D008297:Male; D017711:Nonlinear Dynamics; D051381:Rats; D017208:Rats, Wistar; D013223:Statistics as Topic; D013564:Sympathetic Nervous System / Q000502:physiology*