Prenatal diagnosis of Pentalogy of Cantrell in the first trimester: is 3-dimensional sonography needed?
We report the prenatal diagnosis of 2 cases of Pentalogy of Cantrell in the first trimester. In case 1, sonographic evaluation revealed ectopia cordis, omphalocele, and cystic hygroma at 10 weeks' gestation. In case 2, sonographic assessment during the first trimester detected ectopia cordis and omphalocele at 11 weeks' gestation. In both cases, the patient opted for elective pregnancy termination, and Pentalogy of Cantrell was confirmed in 2 male fetuses. We discuss the role of Doppler imaging and 3-dimensional sonography as complementary methods to conventional sonographic assessment of abdominal wall defects at early pregnancy.
Fetal Medicine Unit, Department of Obstetrics, Fernandes Figueira Institute, Oswaldo Cruz Foundation (IFF-FIOCRUZ), Avenida Rui Barbosa 716, 3 degrees Andar, Flamengo, Rio de Janeiro, Brazil.
Fernando Maia
FM
Peixoto-Filho
Luciana Carneiro
LC
do Cima
Marcos
M
Nakamura-Pereira
D034861:Abdominal Wall / Q000002:abnormalities / Q000000981:diagnostic imaging; D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000601:surgery; D000028:Abortion, Induced; D000328:Adult; D054083:Ectopia Cordis / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006554:Hernia, Umbilical / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D021621:Imaging, Three-Dimensional; D018191:Lymphangioma, Cystic / Q000000981:diagnostic imaging* / Q000601:surgery; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D013249:Sternum / Q000002:abnormalities / Q000000981:diagnostic imaging; D013577:Syndrome; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal / Q000379:methods; D055815:Young Adult