Triterpenoidal saponins from the barks of Zygophyllum fabago L.
Two new triterpenoid saponins, zygophylosides O (1) and P (2), have been isolated from the barks of Zygophyllum fabago L. Their structures were elucidated as 3beta-[(2-O-sulfo-beta-D-xylopyranosyl)oxy]urs-12-ene-27,28-dioic acid and 3beta-[(2-O-sulfo-beta-D-xylopyranosyl)oxy]urs-12-ene-27,28-dioic acid 28-beta-D-glucopyranoside, respectively, by spectral and chemical evidence. Compound 1 showed weaker Nitric Oxide (NO) inhibitory activity.
National Pharmaceutical Engineering Centre for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, PR China.
Yu-Lin
YL
Feng
Bei
B
Wu
He-Ran
HR
Li
Yun-Qiu
YQ
Li
Li-Zhen
LZ
Xu
Shi-Lin
SL
Yang
Susumu
S
Kitanaka
D000818:Animals; D002460:Cell Line; D006868:Hydrolysis; D008264:Macrophages / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D009569:Nitric Oxide / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D012503:Saponins / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013778:Tetrazolium Salts; D013844:Thiazoles; D014315:Triterpenes / Q000302:isolation & purification*; D032445:Zygophyllum / Q000737:chemistry*
D010936:Plant Extracts; D012503:Saponins; D013778:Tetrazolium Salts; D013844:Thiazoles; D014315:Triterpenes; C530115:zygophyloside O; C530116:zygophyloside P; D009569:Nitric Oxide; C022616:thiazolyl blue