Diagnostic and therapeutic challenges owing to concurrent pontine glioma and acute lymphoblastic leukemia.
The presence of 2 active primary tumors in a child is both unusual and challenging. This places the clinician and the family in a difficult situation while planning the treatment. The concurrent presence of a low-grade brain stem glioma and acute lymphoblastic leukemia in a genetically normal girl is presented. The problems encountered with diagnosis and treatment are discussed here.
Anoop
Parameswaran
P
Department of Pediatric Hemato-Oncology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, Surrey, UK.
Hargrave
Darren
D
Zacharoulis
Stergios
S
Saran
Frank
F
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D020295:Brain Stem Neoplasms / Q000473:pathology* / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000628:therapy; D011149:Pons / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000473:pathology*; D016634:Radiosurgery