Phytoecdysteroids from Ajuga macrosperma var. breviflora roots.
Three new phytoecdysteroids, ajugacetalsterones C (1) and D (3) and breviflorasterone (2), were isolated from the roots of Ajuga macrosperma var. breviflora along with five known compounds, namely, 20-hydroxyecdysone, cyasterone, makisterone A, 20-hydroxyecdysone 3-acetate, and 20-hydroxyecdysone 2-acetate. The structures of 1-3 were elucidated on the basis of extensive 1D and 2D NMR spectroscopic studies. The new compounds possess acetal oxygen bridges between C-26 and C-20/C-22, or C-26/C-23, or a lactone bridge between C-26 and C-23.
Departament de Química Orgànica Biològica, Institut d'Investigacions Químiques i Ambientals de Barcelona, Josep Pascual Vila, Consejo Superior de Investigaciones Científicas, Jordi Girona 18-26, 08034 Barcelona, Spain.
Amaya
A
Castro
Josep
J
Coll
Yudelsy A
YA
Tandrón
Anil K
AK
Pant
Chandra S
CS
Mathela
D031328:Ajuga / Q000737:chemistry*; D026461:Ecdysteroids / Q000737:chemistry* / Q000302:isolation & purification*; D007194:India; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D026461:Ecdysteroids; C531884:ajugacetalsterone C; C531885:ajugacetalsterone D; C531886:breviflorasterone