Fibrous ring formation in cirrhotics treated with band ligation.
OBJECTIVE
We observed that the formation of a fibrous ring following variceal eradication appeared to be associated with less variceal recurrence. We aimed to evaluate this formally.


METHODS
Twenty-one cirrhotic patients with a fibrous ring formation in the esophagus after eradication of varices (FR group) were compared with 21 controls of similar age, gender and liver function but without ring formation after eradication in terms of variceal recurrence, portal hypertension related bleeding and survival.


RESULTS
Both groups were similar with regard to baseline demographic and clinical data. During a mean follow-up period of 28.8+/-18.3 (SD) months, variceal recurrence occurred in 2 (9.5%) patients in the FR group compared to 10 (47.6%) in the control group (p=0.005). Cox regression model revealed a significant difference in probability of variceal recurrence between the two groups (p=0.006). In the FR group 1 patient bled and 3 died vs. 2 and 6 patients in the control group respectively. The differences between the groups in relation to bleeding and death were not statistically significant.


CONCLUSIONS
In cirrhotic patients undergoing band ligation for eradication of esophageal varices, the formation of a fibrous ring is followed by a lower variceal recurrence rate.
Triantos
Christos
C
2nd Department of Gastroenterology, Evangelismos General Hospital, Athens, Greece. chtriantos@hotmail.com
Manolakopoulos
Spilios
S
Anastasiou
Jiannis
J
Armonis
Anastasios
A
Saveriadis
Adam
A
Vlachogiannakos
Jiannis
J
Kougioumtzan
Anastasios
A
Bethanis
Sotirios
S
Tzourmakliotis
Dimitrios
D
Karamanolis
Dimitrios
D
Burroughs
Andrew
A
Economopoulos
Theofanis
T
D000368:Aged; D003238:Connective Tissue / Q000473:pathology*; D016145:Endoscopy, Digestive System; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000601:surgery*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications / Q000517:prevention & control; D006801:Humans; D008026:Ligation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence