Surgical management of diabetic foot infections and amputations.
The incidence of diabetes with severe foot infections (eg, necrotizing fasciitis, gas gangrene, ascending cellulitis, infection with systemic toxicity or metabolic instability) has risen significantly during the past decade. Foot infections are a major cause of hospitalization and subsequent lower extremity amputation among patients with diabetes mellitus who have a history of a preexisting ulceration. Surgical management often is required to address severe diabetic foot infections because they can be limb- or life-threatening. Critical limb ischemia, neuropathy, and an immunocompromised host, which often are associated with diabetic foot infections, complicate treatment and are associated with a poorer prognosis.
Zgonis
Thomas
T
Department of Orthopaedics, Podiatry Division, University of Texas Health Science Center, San Antonio, TX, USA.
Stapleton
John J
JJ
Girard-Powell
Valerie A
VA
Hagino
Ryan T
RT
D000671:Amputation, Surgical / Q000379:methods / Q000451:nursing*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000209:etiology; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods / Q000451:nursing*; D017719:Diabetic Foot / Q000150:complications / Q000628:therapy*; D019115:Fasciitis, Necrotizing / Q000209:etiology; D005738:Gas Gangrene / Q000209:etiology; D006801:Humans; D017053:Infection Control; D024802:Nurse's Role; D009730:Nursing Assessment; D009871:Operating Room Nursing / Q000458:organization & administration*; D010347:Patient Care Planning / Q000458:organization & administration; D010348:Patient Care Team / Q000458:organization & administration; D010353:Patient Education as Topic; D019990:Perioperative Care / Q000451:nursing / Q000458:organization & administration; D011300:Preoperative Care / Q000379:methods / Q000451:nursing; D016038:Skin Transplantation; D014946:Wound Infection / Q000209:etiology / Q000628:therapy*
D000900:Anti-Bacterial Agents