Detection of Japanese encephalitis virus antibodies in bats in Southern China.
In this study, 336 bats of eight species were collected during 2004-2007 in six provinces of Southern China. Antibodies against Japanese encephalitis virus (JEV) were detected by ELISA in 43 of 336 (12.8%) serum samples. Among those ELISA-positive samples, 11 serum samples had neutralizing antibodies against JEV. No JEV was detected in brain and liver samples using specific real-time reverse transcriptase-polymerase chain reaction. This is the first report of JEV neutralizing antibodies in bats in China, which reinforces that bats can be involved in the life cycle of this virus.
Cui
Jie
J
School of Life Science, East China Normal University, Shanghai, China.
Counor
Dorian
D
Shen
Di
D
Sun
Guya
G
He
Hongxuan
H
Deubel
Vincent
V
Zhang
Shuyi
S
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002681:China; D002685:Chiroptera / Q000821:virology*; D004664:Encephalitis Virus, Japanese / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D008297:Male; D009500:Neutralization Tests; D020133:Reverse Transcriptase Polymerase Chain Reaction
D000914:Antibodies, Viral