[Pulmonary manifestations of the vasculitides].
The vasculitides involving the lower respiratory tract are mainly the small vessels vasculitides associated with antineutrophil cytoplasmic autoantibodies including Wegener granulomatosis (WG), microscopic polyangiitis (MPA), and Churg-Strauss syndrome (SCS). WG pulmonary manifestations mainly consist of nodules and pneumonias often cavitary, and tracheobronchial stenoses. MPA often consists of pulmonary-renal syndrome with alveolar hemorrhage possibly severe. In SCS, asthma with eosinophilia and further eosinophilic pneumonia are the characteristic pulmonary features. Lung biopsy may be necessary in WG to obtain a definite diagnosis when no other site for biopsy is possible.
Cordier
Jean-François
JF
Service de pneumologie, Centre de référence des maladies orphelines pulmonaires, hôpital Louis-Pradel, Lyon. jean-francois.cordier@chu-lyon.fr
D001249:Asthma / Q000175:diagnosis; D001528:Behcet Syndrome / Q000175:diagnosis / Q000000981:diagnostic imaging; D001706:Biopsy; D001982:Bronchial Diseases / Q000175:diagnosis; D001995:Bronchography; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006469:Hemoptysis / Q000209:etiology; D006470:Hemorrhage / Q000175:diagnosis; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D010995:Pleural Diseases; D010996:Pleural Effusion / Q000175:diagnosis / Q000000981:diagnostic imaging; D011014:Pneumonia / Q000175:diagnosis; D011650:Pulmonary Alveoli; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000175:diagnosis; D014657:Vasculitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology