[Separation and purification of alkaloids from radix of Zanthoxylum nitidum by macroporous adsorption resin].
OBJECTIVE
To obtain the optimal conditions for separating the alkaloids from the extract of Radix of Zanthoxylum nitidum by selecting appropriate macroporous adsorption resins.


METHODS
Eight types of macroporous adsorption were evaluated in separating efficiency with measuring the adsorption ratio and eluting ratio of Alkaloids as indexes.


RESULTS
The XDA-5 macroporous adsorption resin had the best separating efficiency. After enrichment and purification with it, the product purity and yield of alkaloids were up to 33.25% and 90.15%, respectively.


CONCLUSIONS
This method is simple, feasible and fit for industry production.
Liu
Shao
S
Department of Pharmacy, Xiangya Hospital, Center South University, Changsha 410008, China. liushao999@hotmail.com
Zhang
Wei
W
Lei
Peng
P
Li
Xin-Zhong
XZ
Liang
Yi-Zeng
YZ
D000327:Adsorption; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D016062:Porosity; D012116:Resins, Plant / Q000737:chemistry*; D032106:Zanthoxylum / Q000737:chemistry*
D000470:Alkaloids; D012116:Resins, Plant