Autologous chondrocyte implantation: where do we stand now?
Chondral damage to the young knee is common. In symptomatic patients current surgical treatment has focused on filling the defect with fibrocartilage; however, this tissue has poor resistance to shear forces, leading to failure and the onset of degenerative osteoarthritis.
Bone Tumour Unit and Joint Reconstruction Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, UK.
P D
PD
Gikas
W J S
WJ
Aston
T W R
TW
Briggs
D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000628:therapy*; D002358:Cartilage, Articular / Q000293:injuries* / Q000502:physiology / Q000637:transplantation; D019902:Chondrocytes / Q000637:transplantation*; D020219:Chondrogenesis / Q000502:physiology; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014182:Transplantation, Autologous