[Screening for thrombophilia].
For thrombophilia should be screened, if a first thromboembolic event has occurred at the age of less than 45 years, if family history indicates thrombophilia, or in the case of a special clinical condition. To get valid diagnostic results a few pecularities concerning the physiology of coagulation and laboratory medicine have to be considered. This review gives an overview of pitfalls and options during the preanalytical phase of thrombophilia diagnostics. Furthermore, the laboratory assays to perform a screening are highlighted.
Institut für Klinische Chemie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel.
T
T
Lammers
C M
CM
Schambeck
D006403:Hematologic Tests / Q000379:methods*; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D019851:Thrombophilia / Q000175:diagnosis* / Q000517:prevention & control*