Native aortic valve endocarditis caused by Candida sake.
The case is presented of a native valve endocarditis caused by Candida sake in a 34-year-old farmer with no history of intravenous drug abuse or pre-existing valvular abnormality. The patient presented with septicemia and multiorgan dysfunction syndrome (MODS). Clinical and diagnostic work-up revealed findings of severe aortic regurgitation and large vegetations on the aortic valve. Preoperatively, the patient was treated for three weeks with amphotericin B; when the MODS had improved, open-heart surgery with valve replacement was performed. Intravenous amphotericin B was continued postoperatively for three more weeks; a subsequent decision was taken to administer lifelong suppressive antifungal therapy.
Aggarwal
Neera
N
Escorts Heart and Superspeciality Institute, Majitha Verka Byepss Road, Amritsar, Punjab, India. aggarwalneera@yahoo.com
Pannu
Harshbir S
HS
Verma
Puneet
P
Saini
Davinder M
DM
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000000981:diagnostic imaging / Q000188:drug therapy; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008297:Male
D000900:Anti-Bacterial Agents; D000666:Amphotericin B