Pichia anomala fungal keratitis.
OBJECTIVE
To report a case of fungal keratitis of the eye caused by Pichia anomala in a patient with systemic lupus erythematous and Stevens-Johnson syndrome.


METHODS
This was a retrospective chart review.


RESULTS
A 50-year-old woman with systemic lupus erythematosus presented with ocular pain of 4-day duration. Culture of corneal scrapings was positive for P. anomala. Clinically, the organism appeared to respond to topical natamycin, amphotericine B, and oral itraconazole.


CONCLUSIONS
A rare case of P. anomala-associated keratitis was successfully treated with topical amphotericin B, natamycin, and systemic inidazole.
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kyung-Ah
KA
Park
Kyeon
K
Ahn
Eui-Sang
ES
Chung
Tae-Young
TY
Chung
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D010866:Natamycin / Q000627:therapeutic use; D010843:Pichia / Q000302:isolation & purification*; D013262:Stevens-Johnson Syndrome / Q000150:complications
D000935:Antifungal Agents; D007093:Imidazoles; C029899:imidazole; D000666:Amphotericin B; D010866:Natamycin