Selective cauda equina hypertrophy with idiopathic inflammation.
A 20-year-old woman with selective cauda equina hypertrophy presented with muscle weakness and severe pain in the lower extremities. Serial immunotherapy was not effective. We performed biopsy of the cauda equina, and laminectomy and duraplasty of the thoracolumbar region. Biopsy revealed marked infiltration of small lymphocytes and foamy macrophages in the endoneurium. Three years after decompression surgery, her symptoms have improved slightly without progression or relapse. This is the first case of selective cauda equina hypertrophy with idiopathic inflammation. We propose that this is a new disease entity.
Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Japan. hayashiy@gifu-u.ac.jp
Yuichi
Y
Hayashi
Takeo
T
Sakurai
Akio
A
Kimura
Takahide
T
Ikeda
Zenjiro
Z
Matsuyama
Yoshihiro
Y
Suzuki
Yuji
Y
Tanaka
Isao
I
Hozumi
Hideo
H
Hosoe
Hitoshi
H
Takahashi
Takashi
T
Inuzuka
D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009220:Myositis / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D011128:Polyradiculopathy / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D019788:Fluorodeoxyglucose F18; C067980:CD68 antigen, human; D000097382:CD68 Molecule