Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma.
A 66-year old female with HIV-negative classic Kaposi's sarcoma responded to mTOR targeting by rapamycin. The response was well documented by PET-CT. This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in this disease.
Merimsky
Ofer
O
Unit of Bone and Soft Tissue Oncology, Division of Oncology, Tel-Aviv Sourasky Medical Center, 6 Weitzman Street, Tel-Aviv 64239, Israel.
Jiveliouk
Irina
I
Sagi-Eisenberg
Ronit
R