[Separation and purification technology of main active composition of Hongye Xingtong soft capsules with macroporous resin].
OBJECTIVE
To study the technical conditions of the extraction and purification of the active composition from Polygonum orientale and Crataegus pinnatifida Bge. in Hongye Xingtong soft capsules with the macroporous resin.


METHODS
The orientm, isorientm and hyperoside were used as index to screen the five kinds of resins. And the technical conditions of the enrichment and purification of D101 resin selected out of above were all-round studied.


RESULTS
The D101 was fit for adsorbing orientm, isorientm and hyperoside. Under the optimal conditions, the transfer rate of orientm, isorientm and hyperoside was above 91%, and the total solid was cut down by more than 60%.


CONCLUSIONS
The D101 is greatly effective for the enrichment and purification of the active composition of P. orientale and C. pinnatifida Bge.
School of Pharmacy, Guiyang Medical College, Guiyang 550004, China.
Lin
L
Ma
Yong-Lin
YL
Wang
Ai-Min
AM
Wang
Yan-Yu
YY
Lan
Yong-Jun
YJ
Li
Xun
X
He
Yong
Y
Huang
D027825:Crataegus / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D028502:Polygonum / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D012117:Resins, Synthetic / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D012117:Resins, Synthetic; C021304:hyperoside; D011794:Quercetin