Susceptibility testing and molecular classification of Paecilomyces spp.
In vitro susceptibility profiles of 58 Paecilomyces clinical isolates are reported. Amphotericin B, itraconazole, and echinocandins showed poor activity against Paecilomyces lilacinus, while the new triazoles were active against it. Paecilomyces variotii exhibited a different susceptibility pattern, being susceptible to most antifungal agents apart from voriconazole and ravuconazole.
Castelli
Maria Victoria
MV
Servicio de Micologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Carretera Majadahonda-Pozuelo Km2, 28220 Majadahonda, Madrid, Spain.
Alastruey-Izquierdo
Ana
A
Cuesta
Isabel
I
Monzon
Araceli
A
Mellado
Emilia
E
Rodriguez-Tudela
Juan L
JL
Cuenca-Estrella
Manuel
M
D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D004271:DNA, Fungal / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D054714:Echinocandins / Q000494:pharmacology; D017964:Itraconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010143:Paecilomyces / Q000145:classification / Q000187:drug effects* / Q000235:genetics*; D010802:Phylogeny
D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D054714:Echinocandins; D017964:Itraconazole; D000666:Amphotericin B