Neurobehavioral testing in human risk assessment.
Neurobehavioral tests are being increasingly used in human risk assessment and there is a strong need for guidance. The field of neurobehavioral toxicology has evolved from research which initially focused on using traditional neuropsychological tests to identify "abnormal cases" to include methods used to detect sub-clinical deficits, to further incorporate the use of neurosensory assessment, and to expand testing from occupational populations to vulnerable populations including older adults and children. Even as exposures in the workplace are reduced, they have been increasing in the environment and research on exposure has now expanded to cross the entire lifetime. These neurobehavioral methods are applied in research and the findings used for regulatory purposes to develop preventative action for exposed populations. This paper reflects a summary of the talks presented at the Neurobehavioral Testing in Human Risk Assessment symposium presented at the 11th meeting of the International Neurotoxicology Association.
Center for Research on Occupational and Environmental Toxicology, L606, Oregon Health & Science University, Portland, OR 97239, USA. rohlmand@ohsu.edu
Diane S
DS
Rohlman
Roberto
R
Lucchini
W Kent
WK
Anger
David C
DC
Bellinger
Christoph
C
van Thriel
D000328:Adult; D001519:Behavior / Q000187:drug effects*; D002648:Child; D015987:Effect Modifier, Epidemiologic; D004781:Environmental Exposure / Q000706:statistics & numerical data; D006801:Humans; D007509:Irritants / Q000633:toxicity; D020258:Neurotoxicity Syndromes / Q000453:epidemiology* / Q000523:psychology*; D010575:Pesticides / Q000633:toxicity; D011153:Population; D018570:Risk Assessment
D007509:Irritants; D010575:Pesticides