Antihyperlipidemic effect of Casearia sylvestris methanolic extract.
Casearia sylvestris methanolic extract (MCE) was screened at doses of 125-500 mg/kg for its antihyperlipidemic activity. The antihyperlipidemic effect was evaluated in olive oil-loaded mice. Acute treatment caused inhibition in the triglyceride (TG) and serum lipase elevation-induced by 5 ml/kg of olive oil.
Departamento de Farmácia, Universidade do Extremo Sul Catarinense - UNESC, Av. Universitária n(omicron)1105, Bairro: Universitário, CEP: 88806-000, Criciúma - SC, Brazil. tatiana_sch@Yahoo.com.br
Tatiana
T
Schoenfelder
Claus T
CT
Pich
Reginaldo
R
Geremias
Silvio
S
Avila
Elaine N
EN
Daminelli
Rozangela C
RC
Pedrosa
Jane
J
Bettiol
D000818:Animals; D037821:Casearia; D006949:Hyperlipidemias / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D008049:Lipase / Q000097:blood; D008297:Male; D051379:Mice; D000069463:Olive Oil; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage*; D018515:Plant Leaves; D010938:Plant Oils; D014280:Triglycerides / Q000097:blood
D000960:Hypolipidemic Agents; D000069463:Olive Oil; D010936:Plant Extracts; D010938:Plant Oils; D014280:Triglycerides; D008049:Lipase