[Assessment of retinopathy of prematurity].
OBJECTIVE
The study aims to evaluate the ROP, the factors that influence this disease in very low birth weight newborns that are included in the neonatal screening program.


METHODS
It is a retrospective study performed on 82 preterm newborns managed by The Neonatology Department of Obstetrics and Gynecology Clinic I from Cluj over a period of 15 months. There were assessed: prenatal factors, birth, perinatal pathology, therapy received, incidence of ROP and the necessity for laser therapy The statistical analysis has been performed in Epi 6.


RESULTS
The group is composed of 82 newborns with gestational age of 30.01+/-2.18 weeks and birth weight of 1240.19 +/- 347.41 g. The diagnosis of ROP is highly correlated with the gestational age (p = 0.000019) and with the birth weight (p=0.00627). We did not find a significant correlation between the duration of the mechanical ventilation and ROP, but the correlation is obvious with the duration of oxygen-therapy (p=0.005) and FiO2 (p=0.005). From the prenatal factors, we distinguished a high percentage (29.5%) of non followed pregnancies in newborns that developed ROP. The incidence of retinopathy was 39.02% and the laser therapy has been necessary in 14.8% of all cases.


CONCLUSIONS
The incidence of ROP has been 39.02%. The factors that influenced the ROP incidence were: non followed pregnancies, duration of oxygen-therapy, FiO2 applied, pCO2.
Zaharie
Gabriela
G
Catedra de Neonatologie, UMF Iuliu Haţieganu Cluj-Napoca.
Tălu
Simona
S
Stefănut
Claudia
C
Vlăduţiu
Cristina
C
Popa
Monica
M
Szbadi
Liana Kudor
LK
D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D053685:Laser Therapy; D010102:Oxygen Inhalation Therapy / Q000009:adverse effects; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D015995:Prevalence; D012121:Respiration, Artificial / Q000009:adverse effects; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology / Q000601:surgery; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome; D015351:Vision Screening