Nasal encephalocele in a child with Beckwith-Wiedemann syndrome.
Beckwith-Wiedemann syndrome (BWS) is a rare congenital syndrome characterized by gigantism, macroglossia, exophthalmos, postpartum hypoglycemia, and multiple midline defects such as omphalocele. The authors describe, to the best of their knowledge, the first case of a child in whom BWS was diagnosed and who was subsequently treated for a nasal encephalocele. Because the authors believe that this feature might not be an incidental finding in patients with BWS, intranasal masses in these patients should be carefully differentiated, as complications might be severe.
Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands. m.l.d.broekman-4@umcutrecht.nl
Marike L D
ML
Broekman
Eelco W
EW
Hoving
Kuan H
KH
Kho
Lucienne
L
Speleman
K Sen
KS
Han
Patrick W
PW
Hanlo
D001506:Beckwith-Wiedemann Syndrome / Q000473:pathology* / Q000601:surgery; D004677:Encephalocele / Q000473:pathology* / Q000601:surgery; D005005:Ethmoid Sinus; D005260:Female; D006801:Humans; D007223:Infant; D015508:Nasal Obstruction / Q000209:etiology / Q000473:pathology / Q000601:surgery