Synthetic, structural and biological properties of binuclear complexes with some Schiff bases.
The complexes of Co(II), Ni(II) and Cu(II) with N,N'-bis-[5-X-salicylidene]-4,4'-diaminodibenzyl, abbreviated as H2-XSalPDADB (X = -H, -CH3, -Br) have been synthesized and investigated by elemental analysis, electrical conductance, magnetic, spectral and thermal studies. The molar conductivity data indicate that the complexes are non-electrolytes. Analytical data support 1:1 (M:L) stoichiometry. The reflectance spectra along with the magnetic data suggest pseudo-tetrahedral geometry for the complexes. The Schiff bases function as tetradentate ligands coordinating through ON-NO donor system. Substitution in the phenyl ring of the complexes produces shift in the azomethine v(C=N) stretching vibrational frequency, which is related to the Hammett's substituent perameter (sigma). The 1H-NMR data reveal that all Schiff bases exist in enol-iminic form. Various ESR parameters for copper complexes have been calculated. The compounds have been screened for their biological activities.
Patil
Raju M
RM
Department of Chemistry, Institute of Science, 15, Madam Cama Road, Mumbai-400 032, India. rmpatil_2006@yahoo.com
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004553:Electric Conductivity; D004578:Electron Spin Resonance Spectroscopy; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D009532:Nickel / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry* / Q000494:pharmacology; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared
D000900:Anti-Bacterial Agents; D008024:Ligands; D009942:Organometallic Compounds; D012545:Schiff Bases; D003035:Cobalt; D003300:Copper; D009532:Nickel