Analysis of protein surface patterns by pocket similarity network.
In this work, in order to reveal protein surface patterns in a systems biology framework, we analyze the similarity among the surface cavities by investigating the features of the pocket similarity network such as the community structure, the small-world property, the scale-free characteristic, and the hubs.
Liu
Zhi-Ping
ZP
Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100080, China.
Wu
Ling-Yun
LY
Wang
Yong
Y
Zhang
Xiang-Sun
XS
Chen
Luonan
L
D019295:Computational Biology / Q000379:methods*; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D040681:Structural Homology, Protein; D013499:Surface Properties
D011506:Proteins