Evaluation of total disc arthroplasty: a canine model.
The study reported here was designed to examine the biomechanical and histopathologic properties of total disc arthroplasty (TDA) using a canine model. Thirty-seven dogs were divided into 3 groups (intact spine, fusion, TDA) and sacrificed either at study commencement or at 3 months. Results showed progressive fusion from 0 to 3 months in the fusion group. The TDA group maintained motion throughout this period. No neurologic complications were noted in either group. These results establish the canine as a model for future studies of TDA.
Orthopaedic Center of St. Louis, Chesterfield, Missouri, USA.
Brett A
BA
Taylor
Gbolahan O
GO
Okubadejo
Alpesh A
AA
Patel
Micael R
MR
Talcott
Toshii
T
Imamura
Nianbin
N
Hu
Bryan W
BW
Cunningham
D000818:Animals; D001178:Arthroplasty; D019643:Arthroplasty, Replacement / Q000379:methods*; D001696:Biomechanical Phenomena; D004285:Dogs; D007403:Intervertebral Disc / Q000503:physiopathology / Q000601:surgery*; D023421:Models, Animal; D019736:Prostheses and Implants; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D013123:Spinal Fusion