Asymmetry in optic disc morphometry as measured by confocal scanning laser ophthalmoscopy in subjects with hyperopic anisometropia.
OBJECTIVE
To determine whether there is an asymmetry in optic nerve head morphometry in subjects with hyperopic anisometropia.


METHODS
Seventeen men and 20 women with a mean age of 31.43 +/- 2.73 (standard error of mean) years underwent a complete eye examination and optic nerve head topography with the Heidelberg Retina Tomograph II (Heidelberg Engineering, GmBH, Heidelberg, Germany). Differences in optic nerve head parameters between anisometropic eyes and fellow eyes were evaluated using the paired-sample t test or Wilcoxon signed rank test and the correlations between refraction, visual acuity, and disc parameters were evaluated with Spearman's correlation coefficient.


RESULTS
The median refractive errors of hyperopic anisometropic and fellow eyes were +4 D (range: +2.0 to +7.50 D) and 0 D (range: 0 to +4 D), respectively. The mean best-corrected visual acuity of the amblyopic eyes was 0.43 +/- 0.25. The mean disc area of the anisometropic eyes (1.69 +/- 0.35 mm2) was significantly smaller than the fellow eyes (2.01 +/- 0.42 mm2) (P < .001). The differences between eyes in mean cup area, rim area, rim volume, and cup shape were statistically significant (P < .05). In aniosmetropic eyes, refractive error (r = -0.406; P = .013) and visual acuity (r = 0.347; P = .035) showed significant correlations with rim area.


CONCLUSIONS
Hyperopic anisometropia is associated with a remarkable interocular difference in optic disc size and other topographic parameters.
Department of Ophthalmology, Selcuk University Meram Medical Faculty, Konya, Turkey.
Banu
B
Bozkurt
Murat
M
Irkec
Umut
U
Arslan
D000293:Adolescent; D000328:Adult; D000550:Amblyopia / Q000209:etiology; D015858:Anisometropia / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods; D009898:Optic Disk / Q000002:abnormalities*; D014054:Tomography; D014792:Visual Acuity