[Role of Helicobacter species in hepatobiliary diseases].
Helicobacter species have been found in extragastric tissues of humans and mice, and it has been shown that hepatic infection with H. hepaticus causes chronic hepatitis and hepatocellular carcinoma (HCC) in mice. 18 studies of humans with hepatobiliary diseases have been reviewed. In studies of patients with HCC the results imply a pathogen role of Helicobacter species. The same trend was not found in studies of humans with other hepatobiliary diseases. There is no evidence of the possible involvement of Helicobacter species in the development of diseases in the hepatobiliary system.
Rigshospitalet, Klinisk Mikrobiologisk Afdeling 9301.
Maria Engedal
ME
Rasmussen
Liv Ebbeskov
LE
Lauritsen
Leif Percival
LP
Andersen
D000818:Animals; D001660:Biliary Tract Diseases / Q000382:microbiology*; D006528:Carcinoma, Hepatocellular / Q000382:microbiology; D015209:Cholangitis, Sclerosing / Q000382:microbiology; D002764:Cholecystitis / Q000382:microbiology; D016998:Helicobacter / Q000302:isolation & purification; D016481:Helicobacter Infections / Q000382:microbiology*; D006505:Hepatitis / Q000382:microbiology; D006520:Hepatitis, Animal / Q000382:microbiology; D006801:Humans; D008099:Liver / Q000382:microbiology; D008105:Liver Cirrhosis, Biliary / Q000382:microbiology; D008107:Liver Diseases / Q000382:microbiology*; D008113:Liver Neoplasms / Q000382:microbiology; D051379:Mice