Lung cancer mortality in a cohort of workers in a petrochemical plant: occupational or residential risk?
The purpose of the present study is to examine the role of environmental (non occupational) exposures in lung cancer risk among petrochemical workers at a large petrochemical plant built on the Sicilian coast in the immediate vicinity of the town of Gela, Italy in 1960. The cohort included workers employed in the Gela petrochemical plant in 1960-1993. We looked at mortality rates for the period 1960-2002. An internal comparison was performed between two categories of workers with different likelihood of residence in Gela during the period of employment. The rate ratio of mortality from lung cancer comparing "probable residents" with "possible non residents," adjusted for age, calendar period, andjob classification (only blue collar, only white collar and both), was 1.66 (90% Confidence Interval 1.07-2.58). Although the information collected is quite sparse and no inferences can be made about risk sources, the results show a possible excess of residential/environmental risk from lung cancer mortality for those workers more likely to have been residents in Gela.
Pasetto
Roberto
R
Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy. roberto.pasetto@iss.it
Comba
Pietro
P
Pirastu
Roberta
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002617:Chemical Industry; D015331:Cohort Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D010578:Petroleum; D018570:Risk Assessment
D010578:Petroleum