Comparability and reproducibility of the carotid-femoral pulse wave velocity measurements using a multi-element carotid tonometry sensor.
To evaluate the comparability and reproducibility of the carotid-femoral pulse wave velocity (PWV) measured by the newly developed device compared to that measured by the standard device and the validity of brachial-ankle PWV as a substitute of carotid-femoral PWV. We measured aortic PWV twice in 21 normotensive males by using the standard devices and the newly developed device. We also measured brachial-ankle PWV in the same subjects. There was a strong, significant correlation between aortic (carotid-femoral) PWV measured by using two different devices (r = 0.741, P = 0.00012). Interquartile range of the differences of carotid-femoral PWV measured by Form (0.75 m/s (-0.36, 0.39)) was smaller than that by Complior (1.67 m/s (-1.03, 0.63)). There was no correlation between carotid-femoral PWV, measured by either device, and brachial ankle PWV. Our present results suggest that carotid-femoral PWV measured by using Form was comparable to, and may be more reproducible than, that measured by Complior that has been widely used as a predictable marker for cardiovascular events. Our results also suggest brachial-ankle PWV may not be a substitute for carotid-femoral PWV.
Department of Clinical Pharmacology and Therapeutics, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
I
I
Ueda
T
T
Tagawa
S
S
Watanabe
K
K
Yamakawa
T
T
Yasu
S
S
Ueda
D001783:Blood Flow Velocity / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation*; D002339:Carotid Arteries / Q000502:physiology*; D005263:Femoral Artery / Q000502:physiology*; D006801:Humans; D008297:Male; D008365:Manometry / Q000295:instrumentation*; D011673:Pulsatile Flow / Q000502:physiology; D012016:Reference Values; D015203:Reproducibility of Results; D055815:Young Adult