Conclusions and recommendations from the symposium, Beyond Cholesterol: Prevention and Treatment of Coronary Heart Disease with n-3 Fatty Acids.
After the symposium "Beyond Cholesterol: Prevention and Treatment of Coronary Heart Disease with n-3 Fatty Acids," faculty who presented at the conference submitted manuscripts relating to their conference topics, and these are presented in this supplement. The content of these manuscripts was reviewed, and 2 conference calls were convened. The objective was to summarize existing evidence, gaps in evidence, and future research needed to strengthen recommendations for specific intakes of n-3 fatty acids for different conditions relating to cardiovascular disease. The following 2 questions were the main items discussed. What are the roles of n-3 fatty acids in primary versus secondary prevention of coronary heart disease? What are the roles of n-3 fatty acids in hypertriglyceridemia, in the metabolic syndrome and type 2 diabetes, and in sudden cardiac death, cardiac arrhythmias, and vulnerable plaque? Each area was summarized by using 2 general categories: 1) current knowledge for which general consensus exists, and 2) recommendations for research and policy. Additional references for these conclusions can be found in the articles included in the supplement.
Deckelbaum
Richard J
RJ
Institute of Human Nutrition, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA.
Leaf
Alexander
A
Mozaffarian
Dariush
D
Jacobson
Terry A
TA
Harris
William S
WS
Akabas
Sharon R
SR
D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D003327:Coronary Disease / Q000517:prevention & control*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006291:Health Policy; D006801:Humans; D015228:Hypertriglyceridemia / Q000517:prevention & control; D024821:Metabolic Syndrome / Q000517:prevention & control; D012107:Research Design
D015525:Fatty Acids, Omega-3