One-step multicomponent encapsulation by compound-fluidic electrospray.
Fabrication of sophisticated or smart materials often needs controlled integrating multiple components into a single capsule. Most of conventional microencapsulation strategies merely envelop one content into a shell every time. We report a compound-fluidic electrospray method could one-step enclose multiple components into a single microcapsule without contact. The as-prepared microcapsules have multiple compartments inside, in each of which different content can be addressably loaded. This approach gives flexibility for generating diverse microcapsules that could one-step integrate different active components in microscopic domain free of contact, which may find potential applications in multicomponent drug delivery, microreactors and others.
Beijing National Laboratory for Molecular Sciences, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, PR China.
Hongyan
H
Chen
Yong
Y
Zhao
Yanlin
Y
Song
Lei
L
Jiang
D004339:Drug Compounding / Q000295:instrumentation* / Q000379:methods*; D005456:Fluorescent Dyes / Q000737:chemistry; D005990:Glycerol / Q000737:chemistry; D008863:Microspheres; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D014025:Titanium / Q000737:chemistry
D005456:Fluorescent Dyes; D011108:Polymers; C009495:titanium dioxide; D014025:Titanium; D005990:Glycerol