Hypertrophic cardiomyopathy presenting as restrictive cardiomyopathy: a case complicated by biventricular apical aneurysms and papillary fibroelastoma.
This report describes a 45-year-old male patient with nonobstructive hypertrophic cardiomyopathy, biventricular apical aneurysms, and papillary fibroelastoma. Histology revealed muscle fiber disarray, interstitial fibrosis, and mural vessel changes. The wall of the aneurysms showed fat infiltration, and loss and replacement of muscle fibers with fibrous tissues. A review of the literature suggests that this case is the first reported experience with the three pathologies occurring in combination.
Department of Pathology, Toronto General Hospital, Toronto, Ontario, Canada.
Gursharan S
GS
Soor
Moyukh O
MO
Chakrabarti
Raheela F
RF
Siddiqui
Nasir A
NA
Khan
Vivek
V
Rao
Jagdish
J
Butany
D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D002313:Cardiomyopathy, Restrictive / Q000473:pathology*; D003937:Diagnosis, Differential; D005350:Fibroma / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006322:Heart Aneurysm / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006338:Heart Neoplasms / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010210:Papillary Muscles / Q000473:pathology*