Thymoma, myasthenia gravis, and other paraneoplastic syndromes.
The relationship between myasthenia gravis and thymic pathology, including thymoma, is well known. Approximately 10% to 15% of patients who have myasthenia gravis are observed to have a thymoma. Myasthenia gravis may be considered as the most common of the paraneoplastic syndromes in patients who have thymoma. This article summarizes the clinical aspects of myasthenia gravis, followed by a review of the less often recognized paraneoplastic disorders noted to occur in patients who have thymoma.
Department of Neurology, Indiana University School of Medicine, Emerson Hall Room 125, 545 Barnhill Drive, Indianapolis, IN 46202, USA. laumjone@iupui.edu
Laura M
LM
Tormoehlen
Robert M
RM
Pascuzzi
D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents; D009157:Myasthenia Gravis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D010257:Paraneoplastic Syndromes / Q000150:complications*; D013934:Thymectomy / Q000009:adverse effects; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*
D002800:Cholinesterase Inhibitors; D007166:Immunosuppressive Agents