The effects of priming on frontal-temporal communication.
Repeated exposure to a stimulus facilitates its processing. This is reflected in faster and more accurate identification, reduced perceptual identification thresholds, and more efficient classifications for repeated compared with novel items. Here, we test a hypothesis that this experience-based behavioral facilitation is a result of enhanced communication between distinct cortical regions, which reduces local processing demands. A magnetoencephalographic investigation revealed that repeated object classification led to decreased neural responses in the prefrontal cortex and temporal cortex. Critically, this decrease in absolute activity was accompanied by greater neural synchrony (a measure of functional connectivity) between these regions with repetition. Additionally, the onset of the enhanced interregional synchrony predicted the degree of behavioral facilitation. These findings suggest that object repetition results in enhanced interactions between brain regions, which facilitates performance and reduces processing demands on the regions involved.
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Massachusetts Institute of Technology/Harvard Medical School, Boston, MA 02115, USA.
Avniel S
AS
Ghuman
Moshe
M
Bar
Ian G
IG
Dobbins
David M
DM
Schnyer
D001931:Brain Mapping; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D007858:Learning / Q000502:physiology*; D015225:Magnetoencephalography; D008297:Male; D013702:Temporal Lobe / Q000502:physiology*