Acaricidal activity of the hyacinthacine analogues derived from pyrrolizidine alkaloids on Rhipicephalus (Boophilus) microplus.
This study reports the effect of six hyacinthacine analogues derived from pyrrolizidine alkaloids on egg hatchability and mortality rates of newly hatched larvae of the cattle tick Rhipicephalus (Boophilus) microplus. All the compounds were toxic to the larvae of the ticks and inhibited the eggs hatchability in the higher concentration tested (5 microg/ml). Even in the lowest concentration (0.625 microg/ml), some effect in the eggs hatchability was observed.
Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Mônica Oliveira
MO
Duarte
Stela Regina
SR
Ferrarini
Mariane
M
Pazinatto
Eduardo Rolim
ER
de Oliveira
Verônica
V
Rolim
Vera Lucia
VL
Eifler-Lima
Vera Lucia Sardá
VL
Ribeiro
Gilsane
G
von Poser
D000818:Animals; D007306:Insecticides / Q000494:pharmacology*; D015394:Molecular Structure; D011763:Pyrrolizidine Alkaloids / Q000494:pharmacology*; D048494:Rhipicephalus / Q000187:drug effects*; D016019:Survival Analysis
D007306:Insecticides; D011763:Pyrrolizidine Alkaloids; C508850:hyacinthacine A1; C500284:hyacinthacine A2