Staged approach for abdominal wound closure following combined liver and intestinal transplantation from living donors in pediatric patients.
Primary closure of the abdominal wall after combined liver and intestine transplantation from a living donor into a pediatric patient is usually not possible, because of the size of the donor organ, graft edema, and preexisting scars or stomas of the abdominal wall. Closure under tension may lead to abdominal compartment syndrome with vascular compromise and necrosis of the transplanted organ. We describe our experience of abdominal wound closure after liver and intestinal transplant in the pediatric patient using a staged approach. From February 2003 to June 2006, we managed five pediatric liver and intestinal living donor transplant recipients. Because of the large post-transplantation abdominal wall defect, a staged technique of abdominal wound closure was utilized. Initially, an absorbable Polygalactin mesh was sutured around the layer of the defect. As soon as adequate granulation tissue was formed over the mesh a STSG was applied. From the wound stand point all five patients were managed successfully with staged wound closure after transplantation. Granulation tissue filled and covered the mesh within 7.6 wk. A STSG was then used to cover the defect. All infants recovered well and none had a significant wound complication in the immediate post-operative period following STSG. At a mean follow-up of 24 months only one patient developed an entero-cutaneous fistula five months post-transplant. Staged abdominal wall coverage with the use of Polygalactin mesh followed by STSG is a simple and effective technique. A closed wound is achieved in a timely fashion with protection of the viscera. Residual ventral hernia will need to be managed in the future with one of several reconstructive techniques.
Grevious
Mark A
MA
Division of Plastic Surgery, University of Illinois at Chicago, 820 S. Wood Street, Chicago, IL 60612, USA. mgrev@uic.edu
Iqbal
Ronak
R
Raofi
Vandad
V
Beatty
Elizabeth
E
Oberholzer
José
J
Cohen
Mimis
M
Abcarian
Herand
H
Testa
Giuliano
G
Benedetti
Enrico
E
D034841:Abdominal Cavity / Q000601:surgery; D034861:Abdominal Wall / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006547:Hernia / Q000209:etiology; D006801:Humans; D007223:Infant; D007422:Intestines / Q000637:transplantation*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D012189:Retrospective Studies; D013526:Surgical Mesh; D013514:Surgical Procedures, Operative / Q000379:methods*; D013536:Suture Techniques / Q000009:adverse effects*; D014945:Wound Healing