Palladium-catalyzed chloroimination of imidoyl chlorides to a triple bond: an intramolecular reaction leading to 4-chloroquinolines.
In this paper, a new type of effective chloroimination was reported. This reaction afforded 4-chloro-2-perfluoroalkyl quinolines from fluorinated imidoyl chlorides in high yields. This is the first achievement of oxidative addition-reductive elimination type C-Cl bond activation by chloropalladation.
Department of Applied Chemistry, Faculty of Engineering, Okayama University, 3-1-1, Tsushimanaka, Okayama 700-8530, Japan.
Akira
A
Isobe
Jun
J
Takagi
Toshimasa
T
Katagiri
Kenji
K
Uneyama