[Atomic absorption fingerprint and identification studies of Da Huo Luo pill. I. Exploration of inorganic elements fingerprint for establishment of industrial standard].
The fingerprints for most of Chinese medicines based on their organic compositions have been well established. Nevertheless, there are very few known fingerprints which are based on inorganic elements. In order to identify the Da Huo Luo Dan and its efficiency from other Chinese medicines, the authors attempted to set up a fingerprint which could be determined by the measurement of inorganic elements in Da Huo Luo Dan and other Chinese medicines. In the present study, the authors first employed 28 batches of Da Huo Luo Dan produced by Zhang-Shu Pharmatheutical Company in Jiang Xi Province to screen 12 kinds of inorganic elements measured by atomic absorption spectrophotometer and established the atomic absorption fingerprints. Secondly, the authors tried to identify Da Huo Luo Dan and other Chinese medicines by using the similarly analysis of vectors and the statistical analysis of compositional data. The result showed that the methods the authors used here were predictable to tell the efficiency of Da Huo Luo Dan from others. The authors' study also proves that establishment of standard for quality control by analysis of inorganic elements in Chinese medicines is feasible. The present study provides a new idea and a new technique that serve for the establishment of industrial standards for analysis of inorganic elements fingerprint to explore the effects of Chinese medicines.
Center of Analysis and Testing, Nanchang University, Nanchang 330047, China. zqf@ncu.edu.cn
Qi-Feng
QF
Zhang
Long-Yin
LY
Zhu
Shu-Liang
SL
Ding
Chen
C
Wang
Long-Fei
LF
Tu
D002214:Capsules / Q000737:chemistry; D004345:Drug Industry / Q000592:standards; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008672:Metals, Alkali / Q000032:analysis*; D008673:Metals, Alkaline Earth / Q000032:analysis*; D019216:Metals, Heavy / Q000032:analysis*; D013054:Spectrophotometry, Atomic / Q000379:methods*
D002214:Capsules; D004365:Drugs, Chinese Herbal; D008672:Metals, Alkali; D008673:Metals, Alkaline Earth; D019216:Metals, Heavy