An evidence-based strategy for remission in schizophrenia.
Over the past 50 years, the therapeutic goal for schizophrenia has slowly but steadily increased, from one of modest improvement in self-care and control of aggression or self-injury in the 1950s, to effective control of both positive and negative symptoms in the 1990s. As physicians have become more equipped with a better tool kit of pharmacologic and psychosocial interventions, the pessimistic attitude toward long-term outcome has gradually given way to cautious and guarded optimism. Remission may even be considered a potentially realistic goal. This article briefly reviews the status of remission as a therapeutic goal in the treatment of schizophrenia and summarizes available treatment research reporting remission and recovery as clinical outcomes.
Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA. psychiatry@lij.edu
John M
JM
Kane
D014150:Antipsychotic Agents / Q000627:therapeutic use; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D012074:Remission Induction; D012559:Schizophrenia / Q000628:therapy*; D055502:Secondary Prevention
D014150:Antipsychotic Agents