Low molecular peptides as potential inhibitors of plasmin.
Ten peptides of the general formula A-Phe-Lys-X where A = H, H-D-Val, H-L-Val, H-D-Ala, H-L-Ala and X = OH, NH2 were obtained and tested for their antiplasmin activity with the use of amidolytic test.
Department of Organic Chemistry, Medical Academy, 1 Kilińskiego Str., Białystok, Poland. amarkow@amb.edu.pl
Agnieszka
A
Markowska
Krystyna
K
Midura-Nowaczek
Irena
I
Bruzgo
D005341:Fibrinolysin / Q000037:antagonists & inhibitors*; D020128:Inhibitory Concentration 50; D010455:Peptides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D010455:Peptides; D005341:Fibrinolysin