Genetic variability of the 45W gene family between Chinese and Mexican Taenia solium.
Taenia solium 45W proteins are good candidates for development of anti-cysticercosis vaccines. However, the genetic characteristics of the 45 gene family are still unclear between different isolates. We investigated the polymorphism of the 45 gene family between Chinese and Mexican T. solium. Alignment showed that TSO45-4B and TSO45-1C antigens were conserved absolutely, whereas other TSO45 proteins varied between these two isolates. It is informative to guide using of recombinant 45W vaccines to control porcine cysticercosis caused by Asiatic or African/Latin American T. solium.
Zheng
Yadong
Y
Key Laboratory of Zoonoses of CAAS, Lanzhou, Gansu, China.
Cai
Xuepeng
X
Luo
Xuenong
X
Zhang
Dongfeng
D
Jing
Zhizhong
Z
D000818:Animals; D000947:Antigens, Helminth / Q000737:chemistry / Q000276:immunology; D001483:Base Sequence; D003551:Cysticercosis / Q000517:prevention & control / Q000662:veterinary*; D017931:DNA Primers; D014644:Genetic Variation; D016133:Polymerase Chain Reaction; D013045:Species Specificity; D041201:Taenia solium / Q000145:classification / Q000235:genetics* / Q000276:immunology; D014612:Vaccines / Q000276:immunology
D000947:Antigens, Helminth; D017931:DNA Primers; D014612:Vaccines