[Postmenopausal osteoporosis: when is it necessary to perform laboratory testing? Which testing strategy?].
Causes of secondary osteoporosis represent 10 to 20% of all postmenopausal osteoporosis causes. Accordingly, laboratory testing needs to be performed to exclude those conditions before any therapeutic strategy. It is particularly the case in women with a recent fragility fracture or in otherwise healthy women with unexplained low bone mineral density. While there is no consensus for a simple testing strategy, evaluation of serum and urine calcium, phosphate, creatinine with 25-hydroxyvitamin D and complete blood count including erythrocyte sedimentation rate and possibly protein electrophoresis and serum thyroid-stimulating hormone could be recommended.
Unité de ménopause et des maladies osseuses métaboliques, hôpital Paule-de-Viguier, 330, avenue de Grande-Bretagne, 31059 Toulouse cedex 9, France.
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Frayssinet
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Trémollieres
D015519:Bone Density; D002118:Calcium / Q000172:deficiency*; D019411:Clinical Laboratory Techniques; D003937:Diagnosis, Differential; D005260:Female; D050723:Fractures, Bone / Q000517:prevention & control; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000175:diagnosis; D006980:Hyperthyroidism / Q000150:complications / Q000175:diagnosis; D008286:Malabsorption Syndromes / Q000150:complications / Q000175:diagnosis; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis* / Q000209:etiology*; D012307:Risk Factors; D013972:Thyrotropin / Q000097:blood*; D014808:Vitamin D Deficiency / Q000150:complications* / Q000175:diagnosis
D013972:Thyrotropin; D002118:Calcium