Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T.
The marine bacterium Saccharophagus degradans strain 2-40 (Sde 2-40) is emerging as a vanguard of a recently discovered group of marine and estuarine bacteria that recycles complex polysaccharides. We report its complete genome sequence, analysis of which identifies an unusually large number of enzymes that degrade >10 complex polysaccharides. Not only is this an extraordinary range of catabolic capability, many of the enzymes exhibit unusual architecture including novel combinations of catalytic and substrate-binding modules. We hypothesize that many of these features are adaptations that facilitate depolymerization of complex polysaccharides in the marine environment. This is the first sequenced genome of a marine bacterium that can degrade plant cell walls, an important component of the carbon cycle that is not well-characterized in the marine environment.
Weiner
Ronald M
RM
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA. RWeiner@umd.edu
Taylor
Larry E
LE
Henrissat
Bernard
B
Hauser
Loren
L
Land
Miriam
M
Coutinho
Pedro M
PM
Rancurel
Corinne
C
Saunders
Elizabeth H
EH
Longmire
Atkinson G
AG
Zhang
Haitao
H
Bayer
Edward A
EA
Gilbert
Harry J
HJ
Larimer
Frank
F
Zhulin
Igor B
IB
Ekborg
Nathan A
NA
Lamed
Raphael
R
Richardson
Paul M
PM
Borovok
Ilya
I
Hutcheson
Steven
S
D034241:Alteromonadaceae / Q000737:chemistry / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D002874:Chromosome Mapping; D016680:Genome, Bacterial; D006026:Glycoside Hydrolases / Q000235:genetics / Q000378:metabolism; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D021381:Protein Transport; D012623:Seawater / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D015398:Signal Transduction; D013379:Substrate Specificity
D001426:Bacterial Proteins; D011134:Polysaccharides; D006026:Glycoside Hydrolases; C019822:carbohydrase