Cerebellar ataxia following prolonged use of metronidazole: case report and literature review.
Cerebellar toxicity is a rare adverse event in patients treated with metronidazole. Here, we present a patient who developed cerebellar toxicity accompanied by objective abnormalities on magnetic resonance imaging, and review the literature on this unusual reaction. Discontinuation of metronidazole almost always results in resolution of symptoms and structural lesions.
Patel
Kalpeshkumar
K
Department of Internal Medicine, Monmouth Medical Center, 300 Second Avenue, Long Branch, NJ 07740, USA.
Green-Hopkins
Israel
I
Lu
Stanley
S
Tunkel
Allan R
AR
D000890:Anti-Infective Agents / Q000009:adverse effects*; D002524:Cerebellar Ataxia / Q000139:chemically induced* / Q000000981:diagnostic imaging; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008795:Metronidazole / Q000009:adverse effects*; D008875:Middle Aged; D011859:Radiography
D000890:Anti-Infective Agents; D008795:Metronidazole