Histologic examination of Leeds-Keio artificial ligament implanted on the surface of a tumor endoprosthesis.
The Leeds-Keio (L-K) artificial ligament is made of polyester fibers with an open-weave mesh structure. It has been used clinically for knee ligament reconstruction as a scaffold, allowing tissue ingrowth and new ligament formation. We have used the L-K ligament in bone tumor surgery for reattaching remaining muscles to the target zone of a tumor endoprosthesis. We histologically examined the L-K ligament obtained from 2 patients during revision surgery 39 months after the primary surgery. There were dense fibrous tissues between muscles and the L-K ligament. Collagen fibers proliferated in the space between the polyester fibers, and a slight inflammatory reaction was apparent. We concluded that the L-K ligament had a high potential for inducing biological tissue regeneration even on the metal surface.
Department of Orthopaedic Surgery, Yamagata University School of Medicine, Iida-Nishi, Yamagata, Japan.
Toshihisa
T
Osanai
Takashi
T
Tsuchiya
Masato
M
Sugawara
D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation; D001859:Bone Neoplasms / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000175:diagnosis / Q000601:surgery*; D048091:Guided Tissue Regeneration / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D017888:Medial Collateral Ligament, Knee / Q000473:pathology*; D012516:Osteosarcoma / Q000175:diagnosis / Q000601:surgery*; D019736:Prostheses and Implants; D012086:Reoperation; D055815:Young Adult