Acaricidal activity of the hyacinthacine analogues derived from pyrrolizidine alkaloids on Rhipicephalus (Boophilus) microplus.
This study reports the effect of six hyacinthacine analogues derived from pyrrolizidine alkaloids on egg hatchability and mortality rates of newly hatched larvae of the cattle tick Rhipicephalus (Boophilus) microplus. All the compounds were toxic to the larvae of the ticks and inhibited the eggs hatchability in the higher concentration tested (5 microg/ml). Even in the lowest concentration (0.625 microg/ml), some effect in the eggs hatchability was observed.
Duarte
Mônica Oliveira
MO
Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Ferrarini
Stela Regina
SR
Pazinatto
Mariane
M
de Oliveira
Eduardo Rolim
ER
Rolim
Verônica
V
Eifler-Lima
Vera Lucia
VL
Ribeiro
Vera Lucia Sardá
VL
von Poser
Gilsane
G
D000818:Animals; D007306:Insecticides / Q000494:pharmacology*; D015394:Molecular Structure; D011763:Pyrrolizidine Alkaloids / Q000494:pharmacology*; D048494:Rhipicephalus / Q000187:drug effects*; D016019:Survival Analysis
D007306:Insecticides; D011763:Pyrrolizidine Alkaloids; C508850:hyacinthacine A1; C500284:hyacinthacine A2