Contextual specificity of extinction of delay but not trace eyeblink conditioning in humans.
Renewal of an extinguished conditioned response has been demonstrated in humans and in animals using various types of procedures, except renewal of motor learning such as eyeblink conditioning. We tested renewal of delay and trace eyeblink conditioning in a virtual environment in an ABA design. Following acquisition in one context (A, e.g., an airport) and extinction in a different context (B, e.g., a city), tests for renewal took place in the acquisition (A) and extinction context (B), in a counterbalanced order. Results showed renewal of the extinguished conditioned response in the delay but not trace condition.
Mood & Anxiety Disorders Program, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA. christian.grillon@nih.gov
Christian
C
Grillon
Ruben P
RP
Alvarez
Linda
L
Johnson
Chanen
C
Chavis
D000328:Adult; D001288:Attention; D003215:Conditioning, Eyelid; D005108:Extinction, Psychological; D005260:Female; D006801:Humans; D007858:Learning; D008297:Male; D009040:Motion Pictures; D013997:Time Factors