Cardiorespiratory function after operation for pectus excavatum.
OBJECTIVE
We performed a review of current data to determine the effect that operation has on pulmonary function, aerobic capacity, and stroke volume in patients with pectus excavatum.


METHODS
Two reviewers independently assessed clinical trials and collected data on interventions and outcomes. To qualify for inclusion, a study had to include preoperative and postoperative assessment, provide outcomes in either a published percentile or qualified matched control form to control for interval growth, and include only original patient groups.


RESULTS
Postoperative total lung capacity for patients who had Ravitch repair was significantly lower (SMD, 0.71 [CI -1.06, -0.36]; I(2) = 19.6%) than preoperative. Based on 2 studies after removal of the Nuss bar, FEV(1) was significantly increased from preoperative values (SMD, 0.39 [CI, 0.03, 0.74]; I(2) = 0%). Stroke volume increased after surgery (SMD, 0.40 [CI, 0.10, 0.70]; I(2) = 0%) after Ravitch repair. There was a trend toward improved exercise tolerance, but it was not statistically significant.


CONCLUSIONS
Total lung capacity was decreased after Ravitch repair, and FEV(1) was increased after Nuss bar removal. Stroke volume may be increased after Ravitch repair. Exercise tolerance was not improved after either type of surgical repair.
Department of Pediatrics, Mayo Clinic College of Medicine, Rochester, MN, USA.
Jonathan N
JN
Johnson
Tyler K
TK
Hartman
Paul T
PT
Pianosi
David J
DJ
Driscoll
D005660:Funnel Chest / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D011184:Postoperative Period; D013318:Stroke Volume / Q000502:physiology; D014109:Total Lung Capacity / Q000502:physiology*; D016896:Treatment Outcome; D016276:Ventricular Function / Q000502:physiology*