Hippocampal volumes and depression subtypes.
Studies of depression and hippocampal volume have yielded inconsistent results. This inconsistency could stem from the heterogeneity of depressive disorders. We conducted cross-sectional and longitudinal analyses of hippocampal volumes in atypical depressive, melancholic depressive, and control subjects. We found no effect of depression subtype on hippocampal volume or memory performance.
Psychology Research, VA Boston Healthcare System, Boston, MA 02130, USA. dlg@bu.edu
Daniel L
DL
Greenberg
Martha E
ME
Payne
James R
JR
MacFall
David C
DC
Steffens
Ranga R
RR
Krishnan
D000368:Aged; D001284:Atrophy; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests