Biopsy of solid liver tumors: adverse consequences.
BACKGROUND
Percutaneous radiologically-guided liver biopsy is used routinely worldwide in all secondary-level hospital centers. While it has an undoubted role in the investigation and management of acute and chronic inflammatory conditions of the liver, its role in hepatic oncology is doubtful and probably dangerous.


METHODS
We report on two patients who underwent preoperative biopsy of potentially resectable liver tumors.


RESULTS
At the time of surgery, there was evidence of seeding at the biopsy site in both cases. In case 1, potentially curative liver resection was rendered incurable because of gross peritoneal carcinomatosis lying adjacent to the site of liver biopsy. In case 2, the patient underwent curative liver resection, but there was histopathological evidence of peritoneal disease beyond the liver capsule along the falciform ligament at the site of the previous biopsy.


CONCLUSIONS
No patient with a suspicious liver tumor which is thought to be malignant and has any possibility of being a potential candidate for liver surgery, should be subjected to pre-operative diagnostic biopsy in a non-specialist center.
Department of Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK.
Dhya
D
Al-Leswas
Derek A
DA
O'Reilly
Graeme J
GJ
Poston
D001706:Biopsy / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009366:Neoplasm Seeding; D010534:Peritoneal Neoplasms / Q000556:secondary*; D012307:Risk Factors