Analysis of DNA elasticity.
With a model that incorporates hydrodynamics directly, we show that flow experiments can be used for detecting some characteristics of the DNA elasticity which manifest themselves clearly at large length scales but cannot be observed by mechanical forcing experiments even at very small length scales. By systematic analysis, the conclusiveness of different experimental methods is evaluated. For the wormlike chain, confirmed as the correct model for DNA, we find an underlying scaling relation between its extension and flow velocity of the form L(p) approximately v(0.155), which emphasizes the significance of hydrodynamics.
Linna
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RP
Laboratory of Computational Engineering, Helsinki University of Technology, P.O. Box 9203, FIN-02015 HUT, Finland.
Kaski
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D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D004548:Elasticity; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D011108:Polymers / Q000737:chemistry; D013314:Stress, Mechanical; D013816:Thermodynamics
D011108:Polymers; D004247:DNA