Prostate carcinoma metastasis to extraocular muscles.
Prostate carcinoma, when metastatic, typically involves bone and produces both osteoblastic and osteolytic changes. Orbital involvement is uncommon and extraocular muscle enlargement is a rare presentation of metastatic prostate adenocarcinoma. The authors present 2 patients with prostatic tumor metastasis to extraocular muscles. One patient had single-muscle involvement; the other presented with bilateral progressive proptosis, upper eyelid retraction, and bilateral multiple extraocular muscle enlargement mimicking thyroid-associated orbitopathy. Clinicians should be aware that, although rare, prostate cancer can involve the extraocular muscles.
Oculoplastic, Orbital and Oncology Service, Department of Ophthalmology and Visual Sciences, University of Iowa Hospital and Clinics, Iowa City, Iowa 52242-1091, U.S.A.
Adel H
AH
Alsuhaibani
Keith D
KD
Carter
Jeffrey A
JA
Nerad
Andrew G
AG
Lee
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D000369:Aged, 80 and over; D001706:Biopsy; D005134:Eye Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D009801:Oculomotor Muscles / Q000000981:diagnostic imaging / Q000473:pathology* / Q000528:radiation effects; D011471:Prostatic Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed