CCN3-mutant mice are distinct from CCN3-null mice.
A recent manuscript reported phenotypic alterations associated to the expression of a CCN3 protein deleted for the Von Willebrand type C repeat that is common to the various members of the CCN family of proteins. In this comment, the biological significance of these alterations is briefly discussed.
Department of Dermatology, University of Michigan Medical School, Medical Science I, 1150 W. Medical Center Dr., Ann Arbor, MI, 48109-0609, USA, perbalbernard@yahoo.com.
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B
Perbal