[Granular cell tumor].
The granular cell tumor (GCT) or Abrikossoff tumor is a neurogenic tumor often benign with a predominant cervicofacial localization. The mean age of onset ranges between 40 and 60 years of age. Female patients are twice more affected. It is a rare tumor (0.019 to 0.03% of all tumors). The prognosis is usually favorable after surgical excision. The histological aspect is usually specific. Nevertheless, the tumor may be mistaken for a malignant one, especially in case of shallow biopsy. The neurogenic markers and staining by periodic acid Schiff (PAS) help to make the diagnosis. The malignant forms with typical recurrence and metastases are extremely rare and require a wide excision.
Laboratoire d'anatomie et de cytologie pathologiques, CHU Habib-Bourguiba, Sfax, Tunisie. ayadilobna@yahoo.fr
L
L
Ayadi
A
A
Khabir
I
I
Fakhfakh
M H
MH
Abdelmoula
S
S
Makni
T
T
Sellami Boudawara
D000367:Age Factors; D003937:Diagnosis, Differential; D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000473:pathology; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D011379:Prognosis; D012737:Sex Factors