Moraxella bovis pathogenicity: an update.
Moraxella bovis is the etiologic agent of infectious bovine keratoconjunctivitis, the most important ocular disease affecting cattle worldwide. The severity of the cases varied from eyes that exhibited mild signs to severe clinical cases with profuse lacrimation, conjunctival swelling, corneal opacity, and ulceration. Although the mortality is low, there is a high morbidity and important economic loss in terms of significant reduction in production. This paper examines aspects such as the pathogenesis of the disease and the mechanisms by which this unique bacterium is able to disrupt the corneal epithelium and cause infection.
Area de Patología, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (UBA), Chorroarín 280, C1427CWO Ciudad de Buenos Aires, Argentina.
Gabriela Cintia
GC
Postma
Julio César
JC
Carfagnini
Leonardo
L
Minatel
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology* / Q000473:pathology / Q000635:transmission; D004198:Disease Susceptibility; D019573:Epithelium, Corneal / Q000382:microbiology* / Q000473:pathology; D006460:Hemolysin Proteins / Q000378:metabolism; D007639:Keratoconjunctivitis, Infectious / Q000382:microbiology* / Q000473:pathology / Q000635:transmission; D008245:Lysophospholipase / Q000378:metabolism; D016955:Moraxella bovis / Q000201:enzymology / Q000472:pathogenicity*; D045828:Moraxellaceae Infections / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D010447:Peptide Hydrolases / Q000378:metabolism; D014774:Virulence
D006460:Hemolysin Proteins; D008245:Lysophospholipase; D010447:Peptide Hydrolases