[A novel triterpenoid saponin from Prunella vulgaris].
To study the constituents of the Prunella vulgaris L, the constituents were isolated by various column chromatography and the structures were identified on the basis of chemical and spectral analysis. One saponin compound (I) and one flavone glycoside compound (II) were obtained from Prunella vulgaris L. Their structures were elucidated as 16-oxo-17-demethyl-3beta,24-dihydroxylolean-12-en-3-O-beta-D-glucuronoside (I), and acacetin-7-O-beta-D-glucopyranoside (II). Compound I is a novel triterpenoid saponin and named as prunelloside A. Compound II was obtained for the first time from the Prunella genus.
College of Traditional Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China. zhanglanzhen01@126.com
Lan-Zhen
LZ
Zhang
Ya-Jian
YJ
Guo
Guang-Zhong
GZ
Tu
Ren-Bing
RB
Shi
Wen
W
Qin
Yin-Ying
YY
Ba
Fan
F
Yang
D005419:Flavonoids / Q000302:isolation & purification*; D005960:Glucosides / Q000302:isolation & purification*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D031347:Prunella / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D005419:Flavonoids; D005960:Glucosides; D012503:Saponins; D014315:Triterpenes; C477955:acacetin-7-O-glucoside; C542627:prunelloside A