Hematopoietic stem cell transplantation in Langerhans cell histiocytosis: case report and review of the literature.
The prognosis in children with LCH who do not respond to the conventional therapies is very poor. SCT may be a new approach. However, there are limited data about the results of the transplantations. Herein we report a patient with refractory multisystem LCH who underwent allogeneic bone marrow transplantation and is disease and treatment free 54 months after transplantation. Further studies are required to establish the role of SCT in refractory LCH.
Kesik
Vural
V
Department of Pediatric Oncology, School of Medicine, Gulhane Military Medical Academy, Etlik, Ankara, Turkey. vural73@yahoo.com
Citak
Caglar
C
Kismet
Erol
E
Koseoglu
Vedat
V
Akyuz
Canan
C
D016026:Bone Marrow Transplantation; D002675:Child, Preschool; D018380:Hematopoietic Stem Cell Transplantation; D006646:Histiocytosis, Langerhans-Cell / Q000628:therapy*; D006801:Humans; D008297:Male; D011379:Prognosis; D012074:Remission Induction