An exploratory analysis of neurocognition in methamphetamine-induced psychotic disorder and paranoid schizophrenia.
OBJECTIVE
This exploratory study compared the neurocognitive performances of individuals with methamphetamine-induced psychotic disorder (MA psychosis) and paranoid schizophrenia.


BACKGROUND
MA psychosis presents very similarly to paranoid schizophrenia and the relationship between the 2 disorders is not well-understood. Neurocognitive functioning is one potential factor for comparison, as deficits are documented in both schizophrenia and methamphetamine dependence.


METHODS
Participants were selected through chart review. Neurocognitive test scores for participants with paranoid schizophrenia (n=20) and MA psychosis (n=19) were obtained from hospital records and compared.


RESULTS
Results of multivariate analysis of variance found no significant differences between the groups in any neurocognitive domain.


CONCLUSIONS
These preliminary findings suggest that similarities between the disorders may extend to neurocognition. Low power and sampling limitations may contribute to the null findings.
Jacobs
Elizabeth
E
Department of Psychology, University of Hawai'i at Manoa, Honolulu, HI 96822-2294, USA. eajacobs@hawaii.edu
Fujii
Daryl
D
Schiffman
Jason
J
Bello
Iruma
I
D000328:Adult; D019969:Amphetamine-Related Disorders / Q000175:diagnosis* / Q000523:psychology / Q000534:rehabilitation; D000697:Central Nervous System Stimulants / Q000633:toxicity*; D003072:Cognition Disorders / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000633:toxicity*; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011594:Psychometrics; D011605:Psychoses, Substance-Induced / Q000175:diagnosis* / Q000523:psychology; D015203:Reproducibility of Results; D012563:Schizophrenia, Paranoid / Q000139:chemically induced / Q000175:diagnosis* / Q000523:psychology / Q000534:rehabilitation
D000697:Central Nervous System Stimulants; D008694:Methamphetamine