[Dual antiplatelet drug resistance in a patient allergic to clopidogrel: a case report].
In the present report we describe a 70-year-old woman after antimitotic stent implantation who developed an allergy to clopidogrel. We monitored her platelet activity while on different drug regimes and at different time points during the allergic reaction. Tests showed incomplete platelet inhibition by acetylsalicylic acid and clopidogrel (dual antiplatelet drug resistance) during the acute allergic reaction with gradual improvement together with patient clinical status.
Kuliczkowski
Wiktor
W
III Katedra i Oddział Kliniczny Kardiologii, Slaskie Centrum Chorób Serca, ul. Szpitalna 2, Zabrze. wiktor6@wp.pl
Sikora
Jacek
J
Dyrbuś
Krzysztof
K
Kaczmarski
Jacek
J
Gasior
Mariusz
M
Poloński
Lech
L
D000368:Aged; D001241:Aspirin / Q000494:pharmacology*; D000077144:Clopidogrel; D004351:Drug Resistance; D005260:Female; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D015607:Stents / Q000009:adverse effects*; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000494:pharmacology
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin