Securinega suffruticosa.
This review gives an account of the current knowledge on the chemical constituents, biological activity and pharmacological properties of Securinega suffruticosa. A wide range of chemical compounds have been isolated, mainly alkaloids, flavonoids, tannins and lipids. From the pharmacological point of view the most interesting group are the alkaloids, among which securinine, an indolizidine alkaloids containing a unique tricyclic structure.
Department of Pharmacognosy, Wrocław Medical University, pl. Nankiera 1, 50-140 Wrocław, Poland. dankaraj@wp.pl
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D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D000818:Animals; D001381:Azepines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004365:Drugs, Chinese Herbal; D019665:Euphorbiaceae / Q000737:chemistry / Q000502:physiology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006572:Heterocyclic Compounds, Bridged-Ring; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008517:Phytotherapy; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal
D000470:Alkaloids; D001381:Azepines; D004365:Drugs, Chinese Herbal; D006576:Heterocyclic Compounds, 4 or More Rings; D006572:Heterocyclic Compounds, Bridged-Ring; D007783:Lactones; D010880:Piperidines; C000785:securinine