The chick embryo chorioallantoic membrane in the study of tumor angiogenesis.
The chick embryo chorioallantoic membrane (CAM) is commonly used as an experimental in vivo assay to study both angiogenesis and antiangiogenesis in response to tissues, cells or soluble factors. This article summarizes literature data about the use of the CAM in the study of tumor angiogenesis and particularly our experimental data concerning the study of angiogenesis in multiple myeloma and in neuroblastoma.
Ribatti
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Department of Human Anatomy and Histology, University of Bari Medical School, Italy. ribatti@anatomia.uniba.it
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000818:Animals; D049109:Cell Proliferation; D002642:Chick Embryo; D049033:Chorioallantoic Membrane / Q000473:pathology*; D006801:Humans; D009101:Multiple Myeloma / Q000098:blood supply / Q000188:drug therapy; D009369:Neoplasms / Q000098:blood supply* / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000473:pathology*; D009447:Neuroblastoma / Q000188:drug therapy / Q000473:pathology
D020533:Angiogenesis Inhibitors