[Characteristics of responses of rabbit joint structures to intraarticular introduction of calcitonin].
On a model of autoimmune arthritis in rabbits, reduction of inflammatory-destructive process manifestation was observed in all joint tissues under the influence of the intraarticular introduction of calcitonin. Improving metabolic processes in the matrix of tissue-connecting elements of a joint, this specimen inhibits the inflammatory destruction of the subchondral bone and hyaline cartilage in conditions of experimental rheumatoid inflammation.
Belova
S V
SV
Kariakina
E V
EV
D000818:Animals; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000503:physiopathology*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000503:physiopathology*; D001842:Bone and Bones / Q000187:drug effects / Q000503:physiopathology; D002116:Calcitonin / Q000378:metabolism / Q000494:pharmacology*; D002358:Cartilage, Articular / Q000187:drug effects / Q000503:physiopathology*; D004195:Disease Models, Animal; D007270:Injections, Intra-Articular; D007596:Joints / Q000187:drug effects / Q000503:physiopathology*; D011817:Rabbits
C028815:salmon calcitonin; D002116:Calcitonin