Effect of the coherence properties of self-amplified-spontaneous-emission x-ray free electron lasers on single-particle diffractive imaging.
The longitudinal coherence properties of self-amplified-spontaneous- emission x-ray free electron lasers limit the resolution of single-particle diffraction imaging. We found that for the Linac Coherent Light Source (LCLS) at a wavelength of 1.5 A the particles have to be smaller than 500 nm in diameter to achieve atomic-resolution imaging with a resolution length of less than 2 A, suggesting that the longitudinal coherence is sufficient for imaging most biomolecular samples of interest.
Hau-Riege
Stefan P
SP
Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, CA 94551, USA. hauriege1@llnl.gov
D001695:Biology / Q000379:methods; D004583:Electrons; D007834:Lasers; D010316:Particle Size; D012542:Scattering, Radiation