Micro/nanostructured polymeric systems for biomedical and pharmaceutical applications.
This review provides an outline of the polymeric micro/nanostructured advanced systems that are suited for the controlled and targeted administration of, specifically, nonconventional drugs. The contribution of new trends in drug-delivery technology is focused on two major parts, dealing with brief surveys of: the biodegradable/bioerodible polymeric systems used in the formulation of micro/nanoparticles and techniques used in the preparation of micro/nanoparticles for their biomedical application in cancer treatment specifically, in inflammation pathologies, as oxygen carriers (blood substitutes) and in tissue-engineering practice. A small discussion of the future perspectives of the described systems is also given.
Chiellini
Federica
F
Laboratory of Bioactive Polymeric Materials for Biomedical and Environmental Applications - UdR INSTM - Department of Chemistry & Industrial Chemistry, University of Pisa, Pisa, Italy.
Piras
Anna Maria
AM
Errico
Cesare
C
Chiellini
Emo
E
D004339:Drug Compounding / Q000379:methods*; D015195:Drug Design; D008904:Miniaturization; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
D004364:Pharmaceutical Preparations; D011108:Polymers