Serum chromium levels before and after revision surgery for loosened metal-on-metal total hip arthroplasty.
We investigated the changes of serum chromium levels before and after revision surgery in 10 patients (1 male and 9 females) who underwent exchange of a metal-on-metal articulation for a metal-on-polyethylene component because of aseptic loosening of a metal-on-metal total hip prosthesis. Of the 10 patients, 2 had bilateral metal-on-metal total hip arthroplasty. In the 8 patients who had no residual metal articulation, the mean serum chromium levels before and after revision surgery were 2.53 microg/L and 0.46 microg/L, respectively. In the 2 patients who still had a metal articulation on the contralateral side, the mean serum chromium levels before and after revision surgery were 2.85 microg/L and 1.90 microg/L, respectively. Moderate serum chromium levels in patients with metal-on-metal total hip arthroplasty show a decrease after removal of the metal-on-metal articulation.
Department of Orthopedic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Katsuhiko
K
Maezawa
Masahiko
M
Nozawa
Keiji
K
Matsuda
Munehiko
M
Sugimoto
Katsuo
K
Shitoto
Hisashi
H
Kurosawa
D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D002857:Chromium / Q000097:blood*; D002858:Chromium Alloys; D005260:Female; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D020959:Polyethylene; D011475:Prosthesis Failure; D012086:Reoperation
D002858:Chromium Alloys; D008670:Metals; D002857:Chromium; D020959:Polyethylene