Day-night difference in thermoregulatory responses to olfactory stimulation.
Previously, we observed that olfactory stimulation with scent of grapefruit oil (SGFO) or scent of lavender oil (SLVO) affected, elevated or lowered brown adipose tissue temperature (BAT-T) in conscious mice, respectively. In the present study, to test the day-night difference in the actions of olfactory stimulations, we examined the responses of BAT-T and body temperature (BT) measured as the abdominal temperature to SGFO or SLVO during day-time at 14:00 and night-time at 2:00 in conscious rats. In the light period, BAT-T and BT were suppressed after SLVO and elevated after SGFO whereas in the dark period, these parameters remained unchanged with olfactory stimulations. Bilateral lesions of the hypothalamic suprachiasmatic nucleus (SCN) eliminated the effects of olfactory stimulations with SGFO and SVLO on BAT-T and BT. Moreover, sympathetic nerve activity innervating brown adipose tissue (BAT-SNA) changes after SGFO or SLVO were abolished in SCN-lesioned rats. Thus, we concluded that there is day-night difference in the effects of SGFO or SLVO on BAT-T and BT, and that the SCN might be involved in these effects.
Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan. mtanida@sk.ritsumei.ac.jp
Mamoru
M
Tanida
Jiao
J
Shen
Takuo
T
Nakamura
Akira
A
Niijima
Katsuya
K
Nagai
D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001831:Body Temperature / Q000187:drug effects / Q000502:physiology*; D001833:Body Temperature Regulation / Q000187:drug effects / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D027523:Lavandula; D008297:Male; D009812:Odorants; D009822:Oils, Volatile / Q000008:administration & dosage; D009833:Olfactory Pathways / Q000187:drug effects / Q000502:physiology*; D010938:Plant Oils / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar; D013268:Stimulation, Chemical; D013493:Suprachiasmatic Nucleus / Q000293:injuries / Q000502:physiology
D009822:Oils, Volatile; D010938:Plant Oils; C045718:lavender oil