Cryptococcus neoformans, Cryptococcus gattii: serotypes in Venezuela.
Cryptococcus neoformans is one of the medically important yeast-like fungi. C. neoformans var. gatti has been made a species: C. gatti. In our country, there are few studies about these two species and their serotypes. The aim of this study was to determine the distribution of C. neoformans and C. gattii, and their serotypes in Venezuelan clinical isolates. One hundred and twenty C. neoformans and 12 C. gattii clinical isolates were identified by L-canavanine, glycine, and bromothymol blue agar media (CGB). These were investigated by agglutination and adsorption studies with anticryptococcal sera, which were produced by rabbit immunization. Of the 132 isolates 59.8% were typed serotype A (C. neoformans), followed by 25.8% serotype D (C. neoformans), 5.3% serotype AD (C. neoformans), and 5.3% were typed serotype C (var. gattii). Additionally 3.8% were serotype B (C. gattii).
Sección de Micología Médica, Instituto de Medicina Tropical, Universidad Central de Venezuela, Apartado 47408, Los Chaguaramos, Caracas 1041, Venezuela. celinaperezdesalazar@gmail.com
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C
Pérez
M
M
Dolande
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M
Moya
A
A
Roselló
Claudia R Hartung
CR
de Capriles
M E
ME
Landaeta
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S
Mata-Essayag
D000818:Animals; D003453:Cryptococcosis / Q000453:epidemiology* / Q000382:microbiology*; D003454:Cryptococcus / Q000145:classification* / Q000302:isolation & purification; D003455:Cryptococcus neoformans / Q000145:classification* / Q000302:isolation & purification; D003470:Culture Media; D006801:Humans; D007114:Immunization; D016533:Mycological Typing Techniques; D011817:Rabbits; D012703:Serotyping; D013045:Species Specificity; D014687:Venezuela / Q000453:epidemiology
D003470:Culture Media