[Using solutions of hydroxyethyl starch (6% HES 200/0.5 (refortan) and 6% HES 130/0.4 (voluven)) in neuroanesthesiology].
The paper provides the results of a complex experimental and clinical study of the effects of infusion solutions of hydroxyethyl starch (HES 200/0.5--Refortan and HES 130/0.4--Voluven) on hemostatic and systemic hemodynamic parameters in patients operated on for neurosurgical pathology of the brain. The HES solutions are shown to have a more pronounced volemic effect and a slightly higher hypocoagulation effect on the hemostatic system (as compared with physiological solution); the latter does not, however, achieve its clinical value with the used doses of the solutions.
Kondrat'ev
A N
AN
Novikov
V Iu
VIu
Savvina
I A
IA
Driagina
N V
NV
D000758:Anesthesia / Q000379:methods*; D006439:Hemodynamics / Q000187:drug effects; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage* / Q000494:pharmacology; D008875:Middle Aged; D009422:Nervous System Diseases / Q000097:blood / Q000503:physiopathology / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods*; D010642:Phenoxyacetates / Q000008:administration & dosage* / Q000494:pharmacology; D010952:Plasma Substitutes / Q000008:administration & dosage* / Q000494:pharmacology; D010976:Platelet Count
C485123:HES 130-0.4; D006895:Hydroxyethyl Starch Derivatives; D010642:Phenoxyacetates; D010952:Plasma Substitutes; C022160:refortan