Effect of dietary soybean protein level on the plasma homocysteine concentration in rats.
There was an inverse correlation between the plasma homocysteine concentration and dietary protein level or protein intake when a soybean protein isolate (SPI) was used as a protein source for rats. The hepatic cystathionine beta-synthase activity increased in response to the dietary SPI level. The results suggest that a high-protein diet might be an effective means to lower the plasma homocysteine concentration, probably through enhancement of the homocysteine-metabolizing activity.
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, 836 Ohya, Shizuoka 422-8529, Japan.
Hiroshi
H
Okawa
Tatsuya
T
Morita
Kimio
K
Sugiyama
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D006711:Homocystine / Q000097:blood*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D030262:Soybean Proteins / Q000494:pharmacology*
D030262:Soybean Proteins; D006711:Homocystine