The role of retinoids in the adult nervous system and their therapeutic potential.
The mode of action of retinoids in relation to their activity in the adult central nervous system and the potential of synthetic retinoid analogues is reviewed. Investigation into the activity of such molecules will further our understanding of the retinoid pathway during nervous system development and in various neurological disease states.
Christie
V B
VB
School of Biological and Biomedical Sciences, University of Durham, South Road, Durham, DH1 3LE, United Kingdom.
Marder
T B
TB
Whiting
A
A
Przyborski
S A
SA
D000328:Adult; D000818:Animals; D006801:Humans; D008954:Models, Biological; D009420:Nervous System / Q000187:drug effects* / Q000378:metabolism; D009422:Nervous System Diseases / Q000188:drug therapy; D012176:Retinoids / Q000494:pharmacology* / Q000502:physiology*
D012176:Retinoids