Improvement of Lactobacillus plantarum aerobic growth as directed by comprehensive transcriptome analysis.
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that resumption of growth after stagnation correlated with activation of CO(2)-producing pathways, suggesting that a limiting CO(2) concentration induced the stagnation. Analogously, increasing the CO(2) gas partial pressure during aerobic fermentation prevented the temporal growth stagnation.
Stevens
Marc J A
MJ
TI Food and Nutrition, P.O. Box 557, 6700 AN Wageningen, The Netherlands.
Wiersma
Anne
A
de Vos
Willem M
WM
Kuipers
Oscar P
OP
Smid
Eddy J
EJ
Molenaar
Douwe
D
Kleerebezem
Michiel
M
D000332:Aerobiosis; D000693:Anaerobiosis; D002245:Carbon Dioxide / Q000378:metabolism; D005285:Fermentation; D020869:Gene Expression Profiling; D007700:Kinetics; D048191:Lactiplantibacillus plantarum / Q000235:genetics* / Q000254:growth & development*; D014158:Transcription, Genetic
D002245:Carbon Dioxide