Phytochemical investigation of Anaphalis lactea.
Four new compounds, 2',6'-dihydroxy-3'-(2-hydroxy-3-methyl-3-butenyl)-4'-methoxychalcone ( 1), 4,6-dihydroxy-7-isobutyryl-5-prenyl-2(3 H)-benzofuranone ( 4), 7- O-(beta- D-glucopyranosyloxy)-5-hydroxy-1(3 H)-isobenzofuranone ( 6) and (2 R,3 S)-3-methyl-2-(5-oxo-2-isopropenylhexyl)-cyclopentanone ( 7), along with thirteen known compounds were isolated from the whole plant of Anaphalis lactea. Their structures were established based on spectroscopic methods including IR, UV, MS, CD, 1 D NMR and 2 D NMR techniques. Compounds 2, 4 - 6 and 8 - 16 were tested for free-radical scavenging properties in the DPPH assays.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, People's Republic of China.
Zhao-Yan
ZY
Ren
Huan-Yang
HY
Qi
Yan-Ping
YP
Shi
D000975:Antioxidants / Q000302:isolation & purification*; D019659:Asteraceae / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification; D047188:Chalcones / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification
D000975:Antioxidants; D001572:Benzofurans; D047188:Chalcones; D012717:Sesquiterpenes