The role of radiation therapy in the management of sarcomas.
Sarcomas represent a heterogeneous, challenging, and rare group of tumors that present many management challenges. In this article, the authors concentrate on the radiotherapeutic management of sarcomas occurring in the most common locations: the extremities, the trunk, and the retroperitoneum. An overview of the current radiotherapeutic management of soft tissue sarcoma is presented in addition to a discussion of how surgical management may affect radiotherapeutic management. Finally, the authors describe current controversies surrounding the appropriate management of sarcomas with radiotherapy and describe ongoing studies and future areas of research.
Radiation Oncology Branch, National Cancer Center, National Cancer Institute, Building 10, Hatfield CRC, B2-3500, 10 Center Drive, Bethesda, MD 20892, USA.
Aradhana
A
Kaushal
Deborah
D
Citrin
D001918:Brachytherapy; D006801:Humans; D020360:Neoadjuvant Therapy; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery