Isolation of calcium phosphate crystals from complex biological fluids using bisphosphonate-modified superparamagnetic beads.
The surface of superparamagnetic magnetic beads was modified with bisphosphonates to selectively capture calcium phosphate crystals from complex biological fluids (i.e. synovial fluid).
Bioanalytical Chemistry & Diagnostics Group, National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
Aaron
A
Hernandez-Santana
Alexander
A
Yavorskyy
Adedayo
A
Olinyole
Geraldine M
GM
McCarthy
Gillian P
GP
McMahon
D001826:Body Fluids / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry / Q000302:isolation & purification*; D003460:Crystallization; D004164:Diphosphonates / Q000737:chemistry*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties; D013582:Synovial Fluid / Q000737:chemistry
D002130:Calcium Phosphates; D004164:Diphosphonates