Lipodystrophia centrifugalis abdominalis infantilis in a Caucasian girl: report of a case with perieccrine inflammation.
Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is a rare, self-limiting disease typically affecting Asian children around the age of three. In classic cases, patients present with a hypopigmented patch with central atrophy and an erythematous border in the groin area. We present a case of LCAI affecting a female Caucasian toddler that shows striking perieccrine inflammation, a finding not previously reported in this entity. LCAI has been rarely reported in Caucasian children; as a result, there is sparse literature on the histopathological findings in this subset. This case illustrates how significant deep dermal and perieccrine inflammation can be seen in this condition, thus broadening the histopathological spectrum of this disorder.
Sarpa
Hege Grande
HG
Department of Dermatology, University of Utah, Salt Lake City, UT 84132, USA.
Vanderhooft
Sheryll
S
Bowen
Anneli R
AR
D002675:Child, Preschool; D003879:Dermatologic Agents; D004439:Eccrine Glands / Q000473:pathology*; D005260:Female; D006119:Groin / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000188:drug therapy / Q000473:pathology*; D008060:Lipodystrophy / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000627:therapeutic use; D044465:White People
D003879:Dermatologic Agents; C117268:pimecrolimus; D016559:Tacrolimus