Palladium(II)-catalyzed ring enlargement of 2-(arylmethylene)cyclopropylcarbinols: strong effect of substituent electronic nature on the reaction pathway.
In the presence of Pd(II) catalyst and copper(II) bromide, 2-(arylmethylene)cyclopropylcarbinols undergo ring enlargement to deliver (arylcyclobutenyl)carbinols or hydrogenated furans in good yields under mild conditions; mechanisms accounting for the distinct products have been proposed on the basis of control and deuterium labeling experiments.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai, China 200032.
Guo-Qiang
GQ
Tian
Zhi-Liang
ZL
Yuan
Zhi-Bin
ZB
Zhu
Min
M
Shi