Tuberculosis from Mycobacterium bovis in binational communities, United States.
The epidemiology of tuberculosis (TB) in the United States is changing as the incidence of disease becomes more concentrated in foreign-born persons. Mycobacterium bovis appears to be contributing substantially to the TB incidence in some binational communities with ties to Mexico. We conducted a retrospective analysis of TB case surveillance data from the San Diego, California, region from 1994 through 2005 to estimate incidence trends, identify correlates of M. bovis disease, and evaluate risk factors for deaths during treatment. M. bovis accounted for 45% (62/138) of all culture-positive TB cases in children (<15 years of age) and 6% (203/3,153) of adult cases. M. bovis incidence increased significantly (p = 0.002) while M. tuberculosis incidence declined (p<0.001). Almost all M. bovis cases from 2001 through 2005 were in persons of Hispanic ethnicity. Persons with M. bovis were 2.55x (p = 0.01) as likely to die during treatment than those with M. tuberculosis.
University of California San Diego School of Medicine, La Jolla, California 92093-0622, USA. trodwell@ucsd.edu
Timothy C
TC
Rodwell
Marisa
M
Moore
Kathleen S
KS
Moser
Stephanie K
SK
Brodine
Steffanie A
SA
Strathdee
D000293:Adolescent; D000328:Adult; D002140:California / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004641:Emigration and Immigration; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D008875:Middle Aged; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D016012:Poisson Distribution; D012307:Risk Factors; D014376:Tuberculosis / Q000453:epidemiology* / Q000208:ethnology* / Q000382:microbiology / Q000401:mortality; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000208:ethnology / Q000382:microbiology / Q000401:mortality