Immunohistological correlation in different stages of squamous cell carcinoma.
Squamous cell carcinoma is one of the most frequent cutaneous carcinomas, this neoplasic process inducing cellular and tumoral immune response modifications. Our study refers at 60 patients, squamous cell carcinoma diagnosed, at whom we determined IL-2, IL-6 and TNF-alpha, using ELISA technique. The discovered results were different, depending on the differentiation form. The cellular immune response presented important modifications only in poor differentiated form of the disease.
Bălăşoiu
Maria
M
Department of Microbiology-Immunology, University of Medicine and Pharmacy of Craiova, Romania. turculeanu_balasoiu@yahoo.com
Turculeanu
Adriana
A
Mărgăritescu
Cl
C
Avrămescu
Carmen Silvia
CS
Bălăşoiu
A T
AT
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000473:pathology*; D002454:Cell Differentiation; D018450:Disease Progression; D006801:Humans; D007150:Immunohistochemistry; D007376:Interleukin-2 / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D008875:Middle Aged; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D007376:Interleukin-2; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha