[Clinical features of aniridia].
OBJECTIVE
To explore the various clinical features of aniridia and its treatment.


METHODS
It was a retrospective case series. All the 8 cases of 16 aniridia patients in our department from January, 1984 to January, 2007 were assayed. All the patients were bilateral aniridia suffering from abnormal vision and manifested with various degree of cataract, 5 eyes manifested with refractory glaucoma, 8 eyes with horizontal nystagmus. These patients underwent cataract extraction and intraocular lens implantation, trabeculectomy, ciliary process laser photocoagulation, in some of patients glass and cover strabismus exercise, color contact lens therapy were applied.


RESULTS
Vision acuity in all of patients with severe cataract were improved after cataract surgery. One glaucoma eye underwent trabeculectomy, but failed to control the IOP and then received ciliary process laser photocoagulation. Three glaucoma eyes only underwent ciliary process laser photocoagulation, 1 eye received topical anti-glaucoma eye drops. The IOP of 3 eyes was controlled. However, the IOP of 2 eyes was not to be controlled. Vision acuity was improved in 4 strabismus eyes after wearing glass and strabismus exercise, the symptom of photophobia was disappeared in 2 eyes after wearing a pair of color contact lens.


CONCLUSIONS
Although it is hard selection to select the proper treatment for aniridia, most of the cases can obtain a better vision, and relief of the symptom after proper treatment.
Yu
Wei-hong
WH
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Dong
Fang-tian
FT
Li
Jing-zhen
JZ
Mao
Jin
J
D000293:Adolescent; D000328:Adult; D015783:Aniridia / Q000175:diagnosis* / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D015348:Vision, Binocular; D055815:Young Adult