[Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole].
Fundic gland polyps (FGPs) are the most common type of gastric polyps, found primarily in the fundus and body of stomach. Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts. We experienced a patient who showed spontaneous resolution of multiple FGPs after the cessation of omeprazole. Two years ago, the patient showed only endoscopically confirmed erosive esophagitis without FGPs. Multiple FGPs developed one year after the use of omeprazole and spontaneously disappeared with the cessation of omeprazole.
Department of Internal Medicine, College of Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
Jin-Soo
JS
Kim
Hiun Suk
HS
Chae
Hyung-Keun
HK
Kim
Young-Seok
YS
Cho
Yong-Wan
YW
Park
Hye-Suk
HS
Son
Sok-Won
SW
Han
Kyu-Yong
KY
Choi
D000368:Aged; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D005748:Gastric Fundus / Q000473:pathology; D006801:Humans; D008297:Male; D009853:Omeprazole / Q000009:adverse effects*; D011127:Polyps / Q000139:chemically induced* / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000139:chemically induced* / Q000175:diagnosis*
D000897:Anti-Ulcer Agents; D009853:Omeprazole