Sexual precocity associated with an abdominal tumor in an African boy.
We report a 3 year-old boy in Tanzania with an abdominal mass and isosexual precocity due to an hCG-secreting hepatoblastoma. Due to the limited availability of local diagnostic testing, surgery and chemotherapy were completed before immunohistochemical and endocrine results were available.
Bode
H H
HH
School of Paediatrics, University of NSW, Sydney, Australia. henningb2004@yahoo.com
Schimana
W
W
Swai
B
B
Bode
U
U
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006498:Hepatectomy; D018197:Hepatoblastoma / Q000097:blood / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology*; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000032:analysis; D051176:beta Catenin / Q000097:blood
D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D051176:beta Catenin; D005047:Etoposide; D002945:Cisplatin