Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects.
David P
DP
Gavin
Saritha
S
Kartan
Kayla
K
Chase
Dennis R
DR
Grayson
Rajiv P
RP
Sharma
D000107:Acetylation; D056572:Histone Deacetylase Inhibitors; D006655:Histone Deacetylases / Q000378:metabolism; D006657:Histones / Q000378:metabolism*; D006801:Humans; D006877:Hydroxamic Acids / Q000494:pharmacology*; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000201:enzymology*; D012559:Schizophrenia / Q000201:enzymology*
D056572:Histone Deacetylase Inhibitors; D006657:Histones; D006877:Hydroxamic Acids; C012589:trichostatin A; D006655:Histone Deacetylases