Estimation of the relative liver perfusion using two methods of radionuclide angiography in the patients with hemodynamic disorders in the portal system.
The aim of this study is the assessment of the relative arterial and venous contribution to the total liver blood flow (hepatic perfusion index-HPI), with two methods (S1 and S2), and estimation of their value. With this correction, HPI nonsignificantly increases (p>0.05) in all the groups of patients, with a very high correlation between the HPI (S1) and HPI (S2) values (p<0.01). In comparison to the portal perfusion in controls, values were significantly (p<0.01) lower in chronic active hepatitis and liver cirrhosis and differed between themselves (p<0.01). In the groups of cirrhotic patients with esophageal varices, sclerosated esophageal varices, recanalized umbilical vein, portal thrombosis and cavernous portal vein, portal perfusion was lower (p<0.01) than in controls, chronic active hepatitis and liver cirrhosis without collaterals. Both angioscintigraphic methods are useful for the estimation of the disturbances in the portal system. Because of the more exact estimation of the liver perfusion, S2 is recommended.
Institute for Nuclear Medicine, Clinical Center of Serbia.
V M
VM
Artiko
D P
DP
Sobić-Saranović
S V
SV
Pavlović
M S
MS
Perisić-Savić
M V
MV
Stojković
I B
IB
Radoman
S J
SJ
Knezević
M Z
MZ
Vlajković
V B
VB
Obradović
D004932:Esophageal and Gastric Varices / Q000209:etiology / Q000503:physiopathology; D006521:Hepatitis, Chronic / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D006975:Hypertension, Portal / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D011168:Portal System / Q000000981:diagnostic imaging*; D011875:Radionuclide Angiography; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000503:physiopathology