Prognosis of small adenocarcinoma of the lung based on thin-section computed tomography and pathological preparations.
OBJECTIVE
We investigated the relationship between findings from tumor opacity in the mediastinal window image and solid lesions in pathological preparations and related the results to tumor recurrence.


METHODS
The subjects were 115 patients with a lung adenocarcinoma of 20 mm or smaller who underwent surgical resection. The proportion of the reduction in the tumor opacity in the mediastinal window image maximum diameter to the maximum diameter of the tumor opacity was calculated as the reduction percentage, and the proportion of the maximum solid lesions in pathological preparation diameter to the maximum tumor diameter was calculated as the pathological ratio.


RESULTS
The incidence of relapse was significantly higher in patients with a reduction percentage of less than 50% and in patients with a pathological ratio of less than 50%.


CONCLUSIONS
Measurement of the reduction percentage and the pathological ratio may allow prediction of prognosis of small adenocarcinoma of the lung.
Ikehara
Mizuki
M
Division of Respiratory and Infectious Diseases, Department of Internal Medicine, St Marianna University School of Medicine, Yasahi-cho 1197-1, Asahi-ku, Yokohama, Japan. mizukiikehara@aol.com
Saito
Haruhiro
H
Yamada
Kouzo
K
Oshita
Fumihiro
F
Noda
Kazumasa
K
Nakayama
Haruhiko
H
Masui
Kazuo
K
Kameda
Yoichi
Y
Komase
Yuko
Y
Miyazawa
Teruomi
T
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D014057:Tomography, X-Ray Computed / Q000379:methods