Enantioselective syntheses of (-)- and (+)-monomorine I.
A concise enantioselective total synthesis of unnatural (-)-monomorine I has been achieved starting from lactam 2 in 54% overall yield. Natural (+)-monomorine I was also synthesized.
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan. toyooka@pha.u-toyama.ac.jp
Naoki
N
Toyooka
Dejun
D
Zhou
Hideo
H
Nemoto
D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
D007212:Indolizines; C110223:indolizidine-195B