Spectroscopic investigation of 3-pyrazolyl 2-pyrazoline derivative in homogeneous solvents.
How solvent conditions such as solvent polarity and hydrogen-bonding affect the fluorescence of a newly synthesized 3-pyrazolyl 2-pyrazoline derivative (Pyz) having pharmaceutical activity has been explored. The solvatochromic effect of Pyz is due to a change in dipole moment of the compound in the excited state. The relaxation of S1 state is perturbed in hydrogen-bonding solvents. The fluorescence properties of the systems are strongly dependent on the polarity of the media. The non-radiative relaxation process is facilitated by an increase in the polarity of the media. The photophysical response of Pyz in different solvents has been explained considering solute-solvent interactions.
Department of Chemistry, Jadavpur University, Kolkata 700032, India.
Smritimoy
S
Pramanik
Paltu
P
Banerjee
Arindam
A
Sarkar
Attreyee
A
Mukherjee
Kumar K
KK
Mahalanabis
Subhash Chandra
SC
Bhattacharya
D006860:Hydrogen Bonding; D007700:Kinetics; D008956:Models, Chemical; D011720:Pyrazoles / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013053:Spectrophotometry / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013997:Time Factors
D011720:Pyrazoles; D012997:Solvents; C538810:ethyl 1-(4-bromophenyl)-3-(4-cyano-3-methylphenyl-1H-pyrazol-5-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate