Hair follicles--an efficient storage and penetration pathway for topically applied substances. Summary of recent results obtained at the Center of Experimental and Applied Cutaneous Physiology, Charité -Universitätsmedizin Berlin, Germany.
In the past, it was assumed that the intercellular route was the only relevant penetration pathway for topically applied substances. Recent results on follicular penetration obtained at the Center for Experimental and Applied Cutaneous Physiology, Charité - Universitätsmedizin Berlin, Germany, emphasize that the hair follicles represent a highly relevant and efficient penetration pathway and reservoir for topically applied substances.
Lademann
J
J
Center of Experimental and Applied Cutaneous Physiology, Charité - Universitätsmedizin Berlin, Berlin, Germany. Juergen.Lademann@charite.de
Knorr
F
F
Richter
H
H
Blume-Peytavi
U
U
Vogt
A
A
Antoniou
C
C
Sterry
W
W
Patzelt
A
A
D000287:Administration, Topical; D000818:Animals; D003358:Cosmetics / Q000008:administration & dosage / Q000378:metabolism*; D004337:Drug Carriers; D018859:Hair Follicle / Q000378:metabolism*; D006801:Humans; D053758:Nanoparticles; D010539:Permeability; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism*; D012869:Skin Absorption
D003358:Cosmetics; D004337:Drug Carriers; D004364:Pharmaceutical Preparations