Complete and unambiguous assignments of 1H and 13C chemical shifts of new arylamino derivatives of ortho-naphthofuranquinones.
Six new nor-beta-lapachones have been synthesized from reaction of 3-bromo-nor-beta-lapachone with arylamines. These derivatives have potent anticancer properties against several cell lines. Here, we report complete unambiguous assignments of (1)H and (13)C chemical shifts of the new compounds. The assignments were made using a combination of one- and two-dimensional NMR techniques ((1)H, (13)C, (1)H-(1)H COSY, (1)H-(13)C HSQC, and (1)H-(13)C HMBC).
da Silva Júnior
Eufrânio N
EN
Universidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, Campus do Valonguinho, 24020-141, Niterói, RJ, Brazil.
de Souza
Maria Cecília B V
MC
Pinto
Antônio V
AV
Pinto
Maria do Carmo F R
Mdo C
Nogueira
Christiane M
CM
Ferreira
Vitor F
VF
Azeredo
Rodrigo B V
RB
D000588:Amines / Q000737:chemistry; D000970:Antineoplastic Agents / Q000737:chemistry; D002247:Carbon Isotopes; D005663:Furans / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009281:Naphthalenes / Q000737:chemistry; D011809:Quinones / Q000737:chemistry*
D000588:Amines; D000970:Antineoplastic Agents; D002247:Carbon Isotopes; D005663:Furans; D009281:Naphthalenes; D011809:Quinones