What is your diagnosis? Peritoneal fluid from an Arabian horse after colic surgery.
A 16-year-old castrated male Arabian horse was presented to the Purdue University Veterinary Teaching Hospital with a 4-hour history of colic. Initial examinations provided strong evidence for small intestinal obstruction. Abdominal surgery revealed a strangulating lipoma, and 25 feet of small intestine were resected. Postoperatively, the horse developed obstructive ileus due to adhesion formation, which required a second laparotomy. During and after surgery, the abdomen was lavaged with sodium carboxymethylcellulose (CMC). One week after the second surgery, evaluation of peritoneal fluid revealed an inflammatory exudate, with many macrophages containing amorphous to granular, pink to magenta phagocytosed material. Extracellular aggregates of the material were also observed. The material was consistent with CMC. To our knowledge, this report is the first to demonstrate the phagocytosis of CMC by peritoneal fluid macrophages.
Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue Unniversity, West Lafayette, IN 47905, USA. pratts@purdue.edu
Suzanne M
SM
Pratt
John A
JA
Christian
L
L
Paige Jackson
Jan F
JF
Hawkins
Janice E
JE
Sojka
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology*; D002266:Carboxymethylcellulose Sodium; D003085:Colic / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D006734:Horse Diseases / Q000473:pathology* / Q000601:surgery; D006736:Horses; D008067:Lipoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D008264:Macrophages / Q000502:physiology; D008297:Male; D010587:Phagocytosis / Q000502:physiology
D002266:Carboxymethylcellulose Sodium