Global cerebral hypoperfusion in a patient with transient global amnesia.
We report a 64-year-old male patient with pure transient global amnesia (TGA) who exhibited global cerebral hypoperfusion during an amnesia attack. Initial single photon emission computed tomography (SPECT) performed 3 hours after the onset of the amnesic attack revealed diffuse hypoperfusion in the cerebrum, whereas a second SPECT study, 1 month later, revealed improvement of cerebral blood flow. This case suggests that SPECT study is useful in revealing the pathophysiological mechanism of TGA and that TGA attacks are associated with global cerebral blood flow change.
Yamane
Yumiko
Y
Institute for Aging Brain and Cognitive Disorders, Hyogo Brain and Heart Center, 520 Saisho-ko, Himeji, Hyogo, Japan.
Ishii
Kazunari
K
Shimizu
Kotaro
K
Sofue
Keitaro
K
Yoshikawa
Toshiki
T
Miyamoto
Naokazu
N
Ohkawa
Shingo
S
D020236:Amnesia, Transient Global / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D015899:Tomography, Emission-Computed, Single-Photon