Chromosomal localization of nine porcine genes encoding transcription factors involved in adipogenesis.
Chromosomal localization of nine porcine genes encoding transcription factors involved in adipogenesis was determined. BAC clones harboring sequences of selected genes CEBPA (SSC6q12), CEBPB (SSC17q23), CEBPD (SSC4q15), CEBPG (SSC6q12), PPARG (SSC13q24), SREBF1 (SSC10q17), DDIT3 (SSC12q15), GATA2 (SSC13q24 -->q31) and GATA3 (SSC5p12) were mapped by FISH. The positions of these genes in the human and pig genomes were compared. A potential role of the genes encoding adipogenesis factors as candidate genes for fatness traits as well as obesity-related phenotypes is discussed.
Szczerbal
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Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznan, Poznan, Poland. izabel@jay.au.poznan.pl
Chmurzynska
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D050156:Adipogenesis / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D022762:CCAAT-Enhancer-Binding Proteins / Q000235:genetics; D022202:Chromosomes, Artificial, Bacterial / Q000235:genetics; D003582:Cytogenetics; D017931:DNA Primers / Q000235:genetics; D050989:GATA2 Transcription Factor / Q000235:genetics; D017404:In Situ Hybridization, Fluorescence; D047495:PPAR gamma / Q000235:genetics; D013552:Swine / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*
D022762:CCAAT-Enhancer-Binding Proteins; D017931:DNA Primers; D050989:GATA2 Transcription Factor; D047495:PPAR gamma; D014157:Transcription Factors