[Particle release in metal-on-metal bearings. A risk analysis].
Modern metal-on-metal bearings show very low wear rates but release particles and ions from the articulating surfaces into the joint and the whole organism. Especially during the run-in period an increased number of particles is produced. The released metal ions potentially trigger cytotoxic, cancerogenic and allergic reactions, which can impair the patient's health locally or systemically. Many surgeons fear a hypersensitivity reaction to the metal ions of the CoCr alloy in their patients. Today it is assumed that the incidence of these implant-related complications is very low but in some cases it will lead to early failure of the implant. Because the available alternative bearing combinations (ceramic-on-polyethylene and ceramic-on-ceramic) also bear the risk of severe complications, a final statement on the best and safest bearing choice for the patient cannot be made based on the currently existing data.
Heisel
C
C
Labor für Biomechanik und Implantatforschung, Orthopädische Universitätsklinik, Heidelberg. Christian.Heisel@ok.uni-heidelberg.de
Thomsen
M
M
Jakubowitz
E
E
Kretzer
J P
JP
D005549:Foreign-Body Reaction / Q000453:epidemiology*; D006622:Hip Prosthesis / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008670:Metals; D011475:Prosthesis Failure; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors
D008670:Metals