Hypotony maculopathy in a patient with HLA-B27-associated uveitis.
OBJECTIVE
To describe a patient with HLA-B27-associated anterior uveitis who developed hypotony maculopathy.


METHODS
Visual acuity, biomicroscopic slit-lamp examination, and fluorescein angiogram.


RESULTS
Following an episode of acute anterior nongranulomatous HLA-B27-associated uveitis, the patient developed decreased vision, choroidal folds, optic disc edema, and a serous exudative detachment characteristic of hypotony maculopathy. The intraocular pressure was noted to be 4 mmHg. Following therapy with topical 1% prednisolone acetate and 5% homatropine, both the intraocular pressure and retinal anatomy normalized.


CONCLUSIONS
Hypotony maculopathy may be seen in patients with HLA-B27-associated uveitis and should be considered as a cause of vision loss in patients with this condition.
Department of Ophthalmology, California Pacific Medical Center, San Francisco, California, USA.
Richard
R
Roe
Bruno Castelo
BC
Branco
Emmett T
ET
Cunningham
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D015796:HLA-B27 Antigen / Q000097:blood*; D006801:Humans; D007429:Intraocular Pressure; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D015814:Ocular Hypotension / Q000150:complications / Q000209:etiology* / Q000503:physiopathology; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology; D012164:Retinal Diseases / Q000209:etiology*; D014326:Tropanes / Q000627:therapeutic use; D014605:Uveitis / Q000150:complications* / Q000188:drug therapy / Q000276:immunology*; D014786:Vision Disorders / Q000209:etiology
D000893:Anti-Inflammatory Agents; D015796:HLA-B27 Antigen; D014326:Tropanes; C009935:prednisolone acetate; C100236:homatropine; D011239:Prednisolone