Growth hormone inhibits the 11 beta-Hydroxysteroid dehydrogenase type 1 gene promoter activity via insulin-like growth factor I in HepG2 cells.
Li
R-S
RS
Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan. lrs0701@hama-med.ac.jp
Nakagawa
Y
Y
Liu
Y-J
YJ
Fujisawa
Y
Y
Sai
S
S
Nakanishi
T
T
Chapman
K E
KE
Seckl
J R
JR
Ohzeki
T
T
D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1 / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000235:genetics*; D002460:Cell Line; D019382:Human Growth Hormone / Q000494:pharmacology*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000502:physiology*; D008156:Luciferases / Q000378:metabolism; D011401:Promoter Regions, Genetic / Q000187:drug effects*; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D001616:beta-Galactosidase / Q000378:metabolism
D012333:RNA, Messenger; D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I; D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1; D008156:Luciferases; D001616:beta-Galactosidase