Enantioselective cyanosilylation of ketones catalyzed by recyclable polymeric and dimeric Mn(III) salen complexes at room temperature.
Recyclable polymeric 1 and dimeric 2 chiral Mn(III) salen complexes catalyzed enantioselective cyanosilylation of various ketones in the presence of triphenylphosphine oxide as an additive proceeded smoothly at room temperature, providing excellent yields (up to 98%) and enantiomeric excess (up to 86%) of respective cyanohydrin trimethylsilyl ether. For most of the substrates, the Catalyst 1 showed slightly better reactivity and enantioselecitivity than the Catalyst 2 nevertheless both the catalysts were easily recovered and reused four times with the retention of their efficiency.
Khan
Noor-Ul H
NU
Discipline of Inorganic Materials and Catalysis, Central Salt and Marine Chemicals Research Institute (CSMCRI), Bhavnagar, Gujarat, India. khan2593@yahoo.co.in
Agrawal
Santosh
S
Kureshy
Rukhsana I
RI
Abdi
Sayed H R
SH
Prathap
K Jeya
KJ
Jasra
Raksh V
RV
D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D019281:Dimerization; D005029:Ethylenediamines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D013379:Substrate Specificity; D013696:Temperature; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
D003486:Cyanides; D005029:Ethylenediamines; D007659:Ketones; D009942:Organometallic Compounds; D011108:Polymers; D014297:Trimethylsilyl Compounds; D008345:Manganese; C058010:trimethylsilyl cyanide; C011452:disalicylaldehyde ethylenediamine