MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences.
We have developed a computer system, MITOMASTER, to make analysis of human mitochondrial DNA (mtDNA) sequences efficient, accurate, and easily available. From imported sequences, the system identifies nucleotide variants, determines the haplogroup, rules out possible pseudogene contamination, identifies novel DNA sequence variants, and evaluates the potential biological significance of each variant. This system should be beneficial for mtDNA analyses of biomedical physicians and investigators, population biologists and forensic scientists. MITOMASTER can be accessed at http://mammag.web.uci.edu/twiki/bin/view/Mitomaster.
Department of Information and Computer Science, University of California, Irvine, Irvine, California 92697-3940, USA.
Marty C
MC
Brandon
Eduardo
E
Ruiz-Pesini
Dan
D
Mishmar
Vincent
V
Procaccio
Marie T
MT
Lott
Kevin Cuong
KC
Nguyen
Syawal
S
Spolim
Upen
U
Patil
Pierre
P
Baldi
Douglas C
DC
Wallace
D000465:Algorithms; D000818:Animals; D019295:Computational Biology; D004272:DNA, Mitochondrial / Q000737:chemistry*; D030541:Databases, Genetic; D014644:Genetic Variation; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
D004272:DNA, Mitochondrial