Enantioselective cyanosilylation of ketones catalyzed by recyclable polymeric and dimeric Mn(III) salen complexes at room temperature.
Recyclable polymeric 1 and dimeric 2 chiral Mn(III) salen complexes catalyzed enantioselective cyanosilylation of various ketones in the presence of triphenylphosphine oxide as an additive proceeded smoothly at room temperature, providing excellent yields (up to 98%) and enantiomeric excess (up to 86%) of respective cyanohydrin trimethylsilyl ether. For most of the substrates, the Catalyst 1 showed slightly better reactivity and enantioselecitivity than the Catalyst 2 nevertheless both the catalysts were easily recovered and reused four times with the retention of their efficiency.
Discipline of Inorganic Materials and Catalysis, Central Salt and Marine Chemicals Research Institute (CSMCRI), Bhavnagar, Gujarat, India. khan2593@yahoo.co.in
Noor-Ul H
NU
Khan
Santosh
S
Agrawal
Rukhsana I
RI
Kureshy
Sayed H R
SH
Abdi
K Jeya
KJ
Prathap
Raksh V
RV
Jasra
D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D019281:Dimerization; D005029:Ethylenediamines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D013379:Substrate Specificity; D013696:Temperature; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
D003486:Cyanides; D005029:Ethylenediamines; D007659:Ketones; D009942:Organometallic Compounds; D011108:Polymers; D014297:Trimethylsilyl Compounds; D008345:Manganese; C058010:trimethylsilyl cyanide; C011452:disalicylaldehyde ethylenediamine