Concise synthesis of a heptasaccharide antigen found in the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990.
A straight forward synthesis of a heptasaccharide part of the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990, known to have antigenicity, has been achieved in excellent yield. Judicious choice of protecting groups in the intermediates played a significant role throughout the synthesis. Most of the intermediate steps furnished satisfactory yield.
Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226 001, India.
Rajib
R
Panchadhayee
Anup
A
Kumar Misra
D000942:Antigens, Bacterial / Q000737:chemistry / Q000276:immunology*; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002473:Cell Wall / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000737:chemistry*; D008969:Molecular Sequence Data; D009170:Nontuberculous Mycobacteria / Q000276:immunology*; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry
D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D009844:Oligosaccharides