Spared unconscious influences of spatial memory in diencephalic amnesia.
Spatial memory is crucial to our daily lives and in part strongly depends on automatic, implicit memory processes. This study investigates the neurocognitive basis of conscious and unconscious influences of object-location memory in amnesic patients with Korsakoff's syndrome (N = 23) and healthy controls (N = 18) using a process-dissociation procedure in a computerized spatial memory task. As expected, the patients performed substantially worse on the conscious memory measures but showed even slightly stronger effects of unconscious influences than the controls. Moreover, a delayed test administered after 1 week revealed a strong decline in conscious influences in the patients, while unconscious influences were not affected. The presented results suggest that conscious and unconscious influences of spatial memory can be clearly dissociated in Korsakoff's syndrome.
Experimental Psychology, Helmholtz Institute, Utrecht University, Heidelberglaan 2, 3584 CS, Utrecht, The Netherlands. a.postma@uu.nl
Albert
A
Postma
Rémy
R
Antonides
Arie J
AJ
Wester
Roy P C
RP
Kessels
D000222:Adaptation, Physiological / Q000502:physiology; D000328:Adult; D000368:Aged; D000647:Amnesia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D001288:Attention / Q000502:physiology; D003071:Cognition / Q000502:physiology; D003243:Consciousness / Q000502:physiology; D004027:Diencephalon / Q000503:physiopathology; D005260:Female; D006801:Humans; D020915:Korsakoff Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009434:Neural Pathways / Q000503:physiopathology; D009473:Neuronal Plasticity / Q000502:physiology; D009483:Neuropsychological Tests; D020127:Recovery of Function / Q000502:physiology; D013028:Space Perception / Q000502:physiology; D014473:Unconscious, Psychology