Chemical design of nanoparticle probes for high-performance magnetic resonance imaging.
Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular imaging probes. Herein, we present an overview of recent breakthroughs in the development of new synthetic MNP probes with which the sensitive and target-specific observation of biological events at the molecular and cellular levels is possible.
Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
Young-wook
YW
Jun
Jae-Hyun
JH
Lee
Jinwoo
J
Cheon
D000818:Animals; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D015336:Molecular Probe Techniques; D053758:Nanoparticles / Q000737:chemistry