Spatially patterned gradients of synaptic connectivity are established early in the developing retina.
Retinal neurons receive input from other cells via synapses and the position of these synapses on the neurons reflects the retinal regions from which information is received. A new study in Neural Development establishes that the spatial distribution of excitatory synaptic inputs emerges at the onset of synapse formation rather than as a result of changes during neuronal reorganisation.
Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA. scohenco@uci.edu
Susana
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Cohen-Cory
D000818:Animals; D012160:Retina / Q000166:cytology* / Q000196:embryology*; D012165:Retinal Ganglion Cells / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D013569:Synapses / Q000502:physiology*