Urease inhibitor from Datisca cannabina linn.
A new flavonoid datisdirin (1), along with eight known compounds tectochrysine, cearoin, sideroxyline, ursolic acid, corosolic acid, arjunolic acid, erythrodiol and oleanolic acid, were isolated from the ethyl acetate fraction of D. cannabina Linn. The structure of compound 1 was deduced on the basis of its spectral data. Datisdirin showed activity against the ureases enzyme.
Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan. herbalist51@yahoo.com
Mansoor
M
Ahmad
Noor
N
Muhammad
Manzoor
M
Ahmad
Muhammad
M
Arif Lodhi
Noor
N
Jehan
Zahid
Z
Khan
Rosa
R
Ranjit
Farzana
F
Shaheen
Muhammad
M
Iqbal Choudhary
D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D010940:Plant Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D014510:Urease / Q000037:antagonists & inhibitors*
D004791:Enzyme Inhibitors; D005419:Flavonoids; D010940:Plant Proteins; D014510:Urease