Unplanned surgery after drug eluting stent implantation: a strategy for safe temporary withdrawal of dual oral antiplatelet therapy.
We describe four cases of patients with multiple coronary drug eluting stent implantation who underwent major surgery (cardiac and noncardiac) early after stent implantation and needed premature interruption of dual antiplatelet therapy. The transitory withdrawal of oral antiplatelet therapy was accomplished without complications with the use of an IIb/IIIa glycoprotein inhibitor (Tirofiban).
Cardiovascular Department, Cardiology Unit, Hospital of Legnano, Milan, Italy.
Maurizio
M
D'Urbano
Fabio
F
Barlocco
Arnaldo
A
Poli
Raffaela
R
Fetiveau
Pietro
P
Vandoni
Stefano
S
Savonitto
Stefano
S
De Servi
D000284:Administration, Oral; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001241:Aspirin; D000077144:Clopidogrel; D000075202:Contraindications; D004359:Drug Therapy, Combination; D054855:Drug-Eluting Stents; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D011300:Preoperative Care; D013514:Surgical Procedures, Operative; D013988:Ticlopidine / Q000031:analogs & derivatives*; D000077466:Tirofiban; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D014443:Tyrosine; D000077144:Clopidogrel; D000077466:Tirofiban; D013988:Ticlopidine; D001241:Aspirin