Using ChemBank to probe chemical biology.
ChemBank (http://chembank.broad.harvard.edu/) is a public, Web-based informatics environment. ChemBank stores and makes freely available data derived from small molecules and small-molecule screens and has resources for relating and studying these data. Currently, ChemBank stores information on hundreds of thousands of small molecules and hundreds of biomedically relevant assays performed at the Broad Institute screening center. Web-based analysis tools are available within ChemBank to study the relationships between small molecules, cell measurements, and cell states. This unit demonstrates the use of ChemBank data to ask and answer questions relating to chemical biology and screening experiments contained within ChemBank.
Petri Seiler
Kathleen
K
Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Kuehn
Heidi
H
Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Pat Happ
Mary
M
Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
DeCaprio
Dave
D
Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Clemons
Paul A
PA
Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
D003628:Database Management Systems; D016208:Databases, Factual; D004353:Drug Evaluation, Preclinical; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D008967:Molecular Biology / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000737:chemistry*
D004364:Pharmaceutical Preparations