What is the contents of the magic draft IVIg?
Intravenous immunoglobulins (IVIg) consist of IgG concentrated from pooled plasma of numerous donors. Their contents is variable, depending in part on the method of preparation. Natural antibodies and natural autoantibodies are prominent in these preparations and their function. Among these, are the idiotype (Id)/anti-Id dimers. Attention has recently been paid to Fc-gamma receptors and sialylation of the IgG from IVIg.
Seite
Jean-François
JF
Immunology and Pathology Research Unit, Medical School, Brest, France.
Shoenfeld
Yehuda
Y
Youinou
Pierre
P
Hillion
Sophie
S
D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000378:metabolism; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000097:blood / Q000276:immunology* / Q000378:metabolism; D017452:Receptors, IgG / Q000378:metabolism
D001323:Autoantibodies; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007130:Immunoglobulin Idiotypes; D016756:Immunoglobulins, Intravenous; D017452:Receptors, IgG