Relationship between abnormal characteristics of sublingual collateral and portal vein hemodynamic changes in patients with primary hepatic carcinoma.
OBJECTIVE
To investigate the relationship between the abnormal characteristics of sublingual collateral (SC) and portal vein hemodynamic changes in patients with primary hepatic carcinoma (PHC).


METHODS
A total of 123 patients of PHC with abnormal SC were enrolled. The SC characteristics were classified and evaluated. The principal components (PC) of SC extracted from them by principal component analysis and the relationship between PC and the dynamic changes of portal vein flow were analyzed by correlation analysis.


RESULTS
Three groups of PC were extracted, namely PC-1 (length, width, presentation type of visualization), PC-2 (circuitous, vesicular change), and PC-3 (color, collateral hemostasis, petechiae, ecchymosis). Their total accumulative contribution degree reached 56.803%. Correlation analysis shows that PC-1 was significantly positively correlated with the hemodynamic parameters of the portal vein (P<0.01), while PC-2 and PC-3 were not (P>0.05).


CONCLUSIONS
Length, width and presentation type of SC could be used for predicting the changes of portal venous pressure in PHC patients.
Deng
Wei-zhe
WZ
Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.
Lang
Qing-bo
QB
Ling
Chang-quan
CQ
D000328:Adult; D000368:Aged; D003097:Collateral Circulation; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008113:Liver Neoplasms / Q000503:physiopathology*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011169:Portal Vein / Q000503:physiopathology*; D025341:Principal Component Analysis; D014059:Tongue / Q000098:blood supply*