Daphniphyllum and diterpenoid alkaloids from Daphniphyllum longeracemosum.
Four new Daphniphyllum alkaloids, daphlongamines A-D (1-4), were isolated from the fruits of Daphniphyllum longeracemosum. Their structures were characterized by spectroscopic methods, especially 2D NMR techniques. A single-crystal X-ray diffraction analysis was used to confirm the stereochemistry of 3. Remarkably, this is the first report of aconitine- and veatchine-type diterpenoid alkaloids from the genus Daphniphyllum.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Chun-Shun
CS
Li
Ying-Tong
YT
Di
Shu-Zhen
SZ
Mu
Hong-Ping
HP
He
Qiang
Q
Zhang
Xin
X
Fang
Yu
Y
Zhang
Shun-Lin
SL
Li
Yang
Y
Lu
Yan-Qing
YQ
Gong
Xiao-Jiang
XJ
Hao
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031995:Saxifragaceae / Q000737:chemistry*
D000470:Alkaloids; D004224:Diterpenes; D004365:Drugs, Chinese Herbal