Daphniphyllum and diterpenoid alkaloids from Daphniphyllum longeracemosum.
Four new Daphniphyllum alkaloids, daphlongamines A-D (1-4), were isolated from the fruits of Daphniphyllum longeracemosum. Their structures were characterized by spectroscopic methods, especially 2D NMR techniques. A single-crystal X-ray diffraction analysis was used to confirm the stereochemistry of 3. Remarkably, this is the first report of aconitine- and veatchine-type diterpenoid alkaloids from the genus Daphniphyllum.
Li
Chun-Shun
CS
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Di
Ying-Tong
YT
Mu
Shu-Zhen
SZ
He
Hong-Ping
HP
Zhang
Qiang
Q
Fang
Xin
X
Zhang
Yu
Y
Li
Shun-Lin
SL
Lu
Yang
Y
Gong
Yan-Qing
YQ
Hao
Xiao-Jiang
XJ
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031995:Saxifragaceae / Q000737:chemistry*
D000470:Alkaloids; D004224:Diterpenes; D004365:Drugs, Chinese Herbal