Multisystemic therapy for adolescents with poorly controlled type 1 diabetes: reduced diabetic ketoacidosis admissions and related costs over 24 months.
OBJECTIVE
The study aim was to determine if multisystemic therapy (MST), an intensive home-based psychotherapy, could reduce hospital admissions for diabetic ketoacidosis (DKA) in youth with poorly controlled type 1 diabetes over 24 months. Potential cost savings from reductions in admissions were also evaluated.


METHODS
A total of 127 youth were randomly assigned to MST or control groups and also received standard medical care.


RESULTS
Youth who received MST had significantly fewer hospital admissions than control subjects (chi(2) = 11.77, 4 d.f., n = 127; P = 0.019). MST-treated youth had significantly fewer admissions versus their baseline rate at 6-month (P = 0.004), 12-month (P = 0.021), 18-month (P = 0.046), and 24-month follow-up (P = 0.034). Cost to provide MST was 6,934 USD per youth; however, substantial cost offsets occurred from reductions in DKA admissions.


CONCLUSIONS
The study demonstrates the value of intensive behavioral interventions for high-risk youth with diabetes for reducing one of the most serious consequences of medication noncompliance.
Ellis
Deborah
D
Carmen and Anne Adams Department of Pediatrics, Wayne State University, Detroit, Michigan, USA. dellis@med.wayne.edu
Naar-King
Sylvie
S
Templin
Thomas
T
Frey
Maureen
M
Cunningham
Phillippe
P
Sheidow
Ashli
A
Cakan
Nedim
N
Idalski
April
A
D000293:Adolescent; D001521:Behavior Therapy / Q000191:economics; D002648:Child; D003131:Combined Modality Therapy; D003365:Costs and Cost Analysis; D003922:Diabetes Mellitus, Type 1 / Q000191:economics* / Q000628:therapy*; D016883:Diabetic Ketoacidosis / Q000191:economics* / Q000517:prevention & control*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008297:Male; D008824:Michigan; D010290:Parents; D016896:Treatment Outcome
D007004:Hypoglycemic Agents; D007328:Insulin