Radioactive iodine (131I) therapy for thyrotoxicosis at Groote Schuur Hospital over a 6-year period.
The case records of 262 patients who received 131I therapy during a 6-year period were analysed retrospectively. These included seventy-eight patients who received more than one therapeutic dose. The major indication for 131I therapy was thyrotoxicosis occurring in patients aged 40 years and over. The racial incidence in this series is striking. The effects on thyroid function of two low-dose schedules (4 mCi and 6 mCi) were compared. The major complication encountered was hypothyroidism. 4 mCi appears to be as effective as 6 mCi with the added advantage of producing less hypothyroidism.
Thyroid Clinic and Endocrine Research Group, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
J
J
Sagel
S
S
Epstein
J
J
Kalk
W
W
Van Mieghem
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D012189:Retrospective Studies; D013971:Thyrotoxicosis / Q000532:radiotherapy*; D016896:Treatment Outcome; D055815:Young Adult
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals