Cystic undifferentiated sarcoma of liver in children: a pitfall diagnosis in endemic hydatidosis areas.
Undifferentiated (embryonal) sarcoma (UES) of the liver is a very rare pediatric neoplasm with an aggressive behavior. Multimodal treatment including complete surgical resection and chemotherapy has improved survival. We report a case of UES occurring in a 15-year-old female. Radiographic findings showed a multicystic mass appearance. The diagnosis of hydatid cyst was initially presumed. A complete tumor resection after 3 cycles of chemotherapy was performed. Histologically, only 20% of tumor necrosis was noted. Adjuvant chemotherapy was instituted. She remained well at 11 months of follow-up. Cystic appearance is a usual finding in UES. Differential diagnosis with hydatid cyst may be problematic in endemic hydatidosis areas.
Charfi
Slim
S
Laboratoire D'Anatomie et de Cytologie Pathologiques, CHU Habib Bourguiba, Sfax 3029, Tunisia. charfislim@gmail.com
Ayadi
Lobna
L
Toumi
Nabil
N
Frikha
Foued
F
Daoud
Emna
E
Makni
Saloua
S
Frikha
Mounir
M
Beyrouti
Mohamed Issam
MI
Sellami-Boudawara
Tahya
T
D015746:Abdominal Pain / Q000175:diagnosis / Q000209:etiology; D000293:Adolescent; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000175:diagnosis / Q000473:pathology*; D019353:Endemic Diseases; D019160:Endosonography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D018570:Risk Assessment; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014416:Tunisia