Trends in occupational exposure to styrene in the European glass fibre-reinforced plastics industry.
OBJECTIVE
This study presents temporal trends of styrene exposure for workers in the European glass fibre-reinforced plastics (GRP) industry during the period 1966-2002.


METHODS
Data of personal styrene exposure measurements were retrieved from reports, databases and peer-reviewed papers. Only sources with descriptive statistics of personal measurements were accepted. The styrene exposure data cover personal air samples and biological monitoring data, that is, urinary styrene metabolites (mandelic acid and/or phenylglyoxylic acid) and styrene in blood. Means of series of measurements were categorized by year, country, production process, job and sampling strategy. Linear mixed models were used to identify temporal trends and factors affecting exposure levels.


RESULTS
Personal exposure measurements were available from 60 reports providing data on 24145 1-8-h time-weighted average shift personal air samples. Available data of biological exposure indicators included measurements of mandelic acid in post-shift urine (6361 urine samples being analysed). Trend analyses of the available styrene exposure data showed that the average styrene concentration in the breathing zone of open-mould workers in the European GRP industry has decreased on average by 5.3% per year during the period 1966-1990 and by only 0.4% annually in the period after 1990. The highest exposures were measured in Southern Europe and the lowest exposures in Northern Europe with Central Europe in between. Biological indicators of styrene (mandelic acid in post-shift urine) showed a somewhat steeper decline (8.9%), most likely because urine samples were collected in companies that showed a stronger decrease of styrene exposure in air than GRP companies where no biological measurements were carried out.
Van Rooij
J G M
JG
IndusTox Consult, P.O. Box 31070, Nijmegen 6503 CB, the Netherlands. joost.vanrooij@industox.nl
Kasper
A
A
Triebig
G
G
Werner
P
P
Jongeneelen
F J
FJ
Kromhout
H
H
D000395:Air Pollutants, Occupational / Q000032:analysis*; D002617:Chemical Industry / Q000639:trends*; D004784:Environmental Monitoring / Q000379:methods; D005060:Europe; D005898:Glass; D006801:Humans; D016273:Occupational Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D010969:Plastics; D020058:Styrene / Q000032:analysis*
D000395:Air Pollutants, Occupational; D010969:Plastics; C009753:fiberglass; D020058:Styrene