Cooperative interactions between pairs of homologous chromatids during meiosis in Saccharomyces cerevisiae.
We report a novel instance of negative interference during Saccharomyces cerevisiae meiosis, where Cre-mediated recombination between pairs of allelic loxP sites is more frequent than expected. We suggest that endogenous crossover recombination mediates cooperative pairing interactions between all four chromatids of a meiotic bivalent.
Genetics Graduate Group, Section of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.
Joshua Chang
JC
Mell
Kelly
K
Komachi
Owen
O
Hughes
Sean
S
Burgess
D000483:Alleles; D002842:Chromatids / Q000235:genetics*; D023902:Chromosome Pairing; D015825:Chromosomes, Fungal / Q000235:genetics; D003434:Crossing Over, Genetic; D008540:Meiosis / Q000235:genetics*; D008957:Models, Genetic; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000235:genetics*; D012854:Sister Chromatid Exchange