[Phage lytic enzymes--new hope in battle against bacterial infections].
Bacteriophage lytic enzymes are produced during phage replication cycle in bacterial cells. Lysis of bacterial cell wall enables release of virus particles. Bakteriophage enzymes activity are highly specific, therefore they are able to destroy selected bacterial species, also resistant to antibiotics. This creates new possibilities in therapy of bacterial infections.
Niczyporuk
Jowita Samanta
JS
Ośrodek Diagnostyki i Zwałczania Zagrozén Biologicznych Wojskowego Instytutu Higieny i Epidemiologii.
Bartoszcze
Michał
M
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001408:Bacillus anthracis / Q000187:drug effects / Q000472:pathogenicity / Q000821:virology; D001424:Bacterial Infections / Q000188:drug therapy*; D001435:Bacteriophages / Q000201:enzymology*; D010450:Endopeptidases / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D010457:Peptidoglycan / Q000378:metabolism; D013210:Staphylococcus / Q000187:drug effects / Q000472:pathogenicity / Q000821:virology
D000900:Anti-Bacterial Agents; D010457:Peptidoglycan; D010450:Endopeptidases; C001143:endolysin