Primary prevention of sudden cardiac death using implantable cardioverter defibrillators.
Despite substantial advances in prevention and treatment of cardiovascular diseases, sudden cardiac death (SCD) remains a leading cause of death in industrialized countries. Implantable cardioverter defibrillator (ICD) has been demonstrated to be an attractive option for primary prevention of SCD in high-risk patients. This review discusses the progress in the risk stratification for selecting high-risk patients, highlights the clinical trials of primary prevention for SCD, outlines the efficacy of combined use of cardiac resynchronization therapy with ICD, and analyses the cost-effectiveness issue of this device.
Ding
Ligang
L
Center of Arrhythmia, Fuwai Cardiovascular Hospital, Peking Union Medical College, Beijing, China.
Hua
Wei
W
Niu
Hongxia
H
Chen
Keping
K
Zhang
Shu
S
D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D006333:Heart Failure / Q000517:prevention & control*; D006801:Humans; D011322:Primary Prevention / Q000295:instrumentation* / Q000379:methods* / Q000592:standards; D016896:Treatment Outcome