A chiral pool approach to the synthesis of optically active tetrahalo norbornyl building blocks.
Optical antipodes of the mono- and disubstituted polyhalo norbornyl derivatives were prepared in excellent yields. The monosubstituted derivatives 7 were obtained with good enantiopurities. A kaleidoscopic change in the product formation and distribution was observed by changing the chronology of reactions.
Department of Chemistry, Indian Institute of Technology, Kanpur, India. faiz@iitk.ac.in
Faiz Ahmed
FA
Khan
Ch
Ch
Sudheer