Lipid droplets: a classic organelle with new outfits.
Lipid droplets are depots of neutral lipids that exist virtually in any kind of cell. Recent studies have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only to lipid homeostasis but also to diverse cellular functions. Because of the unique structure as well as the functional importance in relation to obesity, steatosis, and other prevailing diseases, the lipid droplet is now reborn as a brand new organelle, attracting interests from researchers of many disciplines.
Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, 466-8550, Japan. tfujimot@med.nagoya-u.ac.jp
Toyoshi
T
Fujimoto
Yuki
Y
Ohsaki
Jinglei
J
Cheng
Michitaka
M
Suzuki
Yuki
Y
Shinohara
D000818:Animals; D003593:Cytoplasm / Q000648:ultrastructure; D022162:Cytoplasmic Vesicles / Q000737:chemistry / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000737:chemistry* / Q000648:ultrastructure*; D008055:Lipids / Q000737:chemistry*; D015388:Organelles / Q000737:chemistry* / Q000648:ultrastructure*; D011506:Proteins / Q000378:metabolism
D008055:Lipids; D011506:Proteins