2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines.
Microwave irradiations of 2-(aminoaryl)alkanone O-phenyl oximes and carbonyl compounds generate iminyl radicals in company with imines; iminyl on imine ring closure yields dihydroquinazolines or quinazolines when ZnCl2 is included in the mixture.
Portela-Cubillo
Fernando
F
University of St. Andrews, School of Chemistry, EaStChem, St. Andrews, Fife, UK KY16 9ST.
Scott
Jackie S
JS
Walton
John C
JC
D000473:Alkanes / Q000737:chemistry*; D000586:Amination; D002712:Chlorides / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
D000473:Alkanes; D002712:Chlorides; D007202:Indicators and Reagents; D010091:Oximes; D011799:Quinazolines; D017967:Zinc Compounds; C016837:zinc chloride