Management of optic neuritis in Canada: survey of ophthalmologists and neurologists.
BACKGROUND
Acute isolated optic neuritis is often the first manifestation of multiple sclerosis (MS), and its management remains controversial. Over the past decade, with the advent of new disease-modifying agents, management of isolated optic neuritis has become more complicated.


OBJECTIVE
To evaluate the current practice patterns of Canadian ophthalmologists and neurologists in the management of acute optic neuritis, and to evaluate the impact of recently published randomized clinical trials.


METHODS
Mail survey.


METHODS
All practicing ophthalmologists and neurologists in Canada were mailed a survey evaluating the management of isolated acute optic neuritis and familiarity with recent clinical trials. Surveys for 1158 were mailed, and completed surveys were collected anonymously through a datafax system. Second and third mailings were sent to non-respondents 6 and 12 weeks later.


RESULTS
The final response rate was 34.5%. Although many acute optic neuritis patients initially present to ophthalmologists, neurologists are the physicians primarily managing these patients. Ordering magnetic resonance imaging, and treating with high dose intravenous steroids has become the standard of care. However, 15% of physicians (14% of ophthalmologists and 16% of neurologists) continue to prescribe low dose oral steroids, and steroids are being given for reasons other than to shorten the duration of visual symptoms by 73% of ophthalmologists and 50% of neurologists. More neurologists than ophthalmologists are familiar with recent clinical trials involving disease-modifying agents.


CONCLUSIONS
Although the management of acute optic neuritis has been evaluated in large clinical trials that were published in major international journals, some ophthalmologists and neurologists are not following evidence-based recommendations.
Division of Neurology, University of Saskatchewan, Saskatoon, SK, Canada.
Edward J
EJ
Atkins
Carolyn D
CD
Drews-Botsch
Nancy J
NJ
Newman
Olivier
O
Calvetti
Seegar
S
Swanson
Valérie
V
Biousse
D002170:Canada / Q000453:epidemiology; D006306:Health Surveys; D006801:Humans; D009462:Neurology / Q000379:methods / Q000706:statistics & numerical data*; D009885:Ophthalmology / Q000379:methods / Q000706:statistics & numerical data*; D009902:Optic Neuritis / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data