[Adrenal failure caused by primary adrenal non-Hodgkin lymphoma: a case report and review of the literature].
We report a case of 78-year old man who presented with symptoms of adrenal insufficiency. The computed tomography (CT) scan showed the presence of bilateral adrenal masses. A CT-scan guided needle biopsy revealed diffuse large- B cell lymphoma. The absence of pathological findings in clinical, bone marrow and CT scan examinations supported the diagnosis of primary non-Hodgkin Lymphoma of the adrenal glands. The patient was treated with four cycles of R-CHOP chemotherapy with Rituximab, liposomal Doxorubicin, Cyclophosphamide, Vincristine and Prednisolone. At the end of fourth cycle there was radiological improvement but the chemotherapy was stopped because of IV grade toxicity. He completed treatment with radiotherapy of right adrenal mass. Few days after finishing radiation therapy the patient died due to a disseminated infection. No progressive disease was founded.
Hernández Marín
B
B
Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Díaz Muñoz de la Espada
V M
VM
Alvarez Alvarez
R
R
Encinas García
S
S
Khosravi Shahi
P
P
Pérez Fernández
R
R
Pérez Manga
G
G
D000310:Adrenal Gland Neoplasms / Q000150:complications*; D000309:Adrenal Insufficiency / Q000209:etiology*; D000368:Aged; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D008297:Male