[Impregnate occasion for male renal transplant recipients].
OBJECTIVE
To explore the impregnate occasion for male renal transplant recipients.


METHODS
Twenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at the dose of 4.1-6 mg/[kg x d]), 11 in Group B (6-24 months and 2.1-4 mg/[kg x d]) and 8 in Group C (longer than 24 months and 1.3-2 mg/[kg x d]). The semen of the patients were detected and compared with those of 12 normal volunteers.


RESULTS
Statistically significant differences were observed in sperm motility and sperm head deformity between Group A and C (P < 0.05), but not in pH value and sperm volume, vitality and concentration among the 3 groups (P > 0.05).


CONCLUSIONS
For male renal transplant recipients, 2 years or longer after the transplantation is the most suitable time for impregnation.
Xu
Long-Gen
LG
Renal Transplantation and Blood Purification Center, 117th Hospital of PLA, Hangzhou, Zhejiang 310013, China. xulonggen@sina.com
Zhu
Xiao-Feng
XF
Jin
Li-Ming
LM
Xu
Hui-Ming
HM
Ling
Xia
X
Tang
Xiao-Yang
XY
Xu
Biao
B
D000328:Adult; D003075:Coitus; D016572:Cyclosporine / Q000008:administration & dosage* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D016030:Kidney Transplantation; D008297:Male; D011184:Postoperative Period; D012661:Semen / Q000737:chemistry / Q000166:cytology / Q000187:drug effects; D013076:Sperm Count; D013081:Sperm Motility / Q000187:drug effects; D013997:Time Factors
D007166:Immunosuppressive Agents; D016572:Cyclosporine