What is the contents of the magic draft IVIg?
Intravenous immunoglobulins (IVIg) consist of IgG concentrated from pooled plasma of numerous donors. Their contents is variable, depending in part on the method of preparation. Natural antibodies and natural autoantibodies are prominent in these preparations and their function. Among these, are the idiotype (Id)/anti-Id dimers. Attention has recently been paid to Fc-gamma receptors and sialylation of the IgG from IVIg.
Immunology and Pathology Research Unit, Medical School, Brest, France.
Jean-François
JF
Seite
Yehuda
Y
Shoenfeld
Pierre
P
Youinou
Sophie
S
Hillion
D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000378:metabolism; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000097:blood / Q000276:immunology* / Q000378:metabolism; D017452:Receptors, IgG / Q000378:metabolism
D001323:Autoantibodies; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007130:Immunoglobulin Idiotypes; D016756:Immunoglobulins, Intravenous; D017452:Receptors, IgG