Systemic therapy for psoriasis.
Psoriasis therapy has changed dramatically in the past decade with the introduction of biologic therapy. The treatment of moderate to severe psoriasis is reviewed. Phototherapy, conventional systemic therapy, and biologic therapy are discussed including practical tips for administering each agent. Overall approaches to treatment are discussed along with special circumstances where individual therapies have advantages.
Lee
Melvin
M
State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Department of Dermatology, Buffalo, NY, USA.
Kalb
Robert E
RE
D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy* / Q000628:therapy; D011993:Recombinant Fusion Proteins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D014467:Ultraviolet Therapy / Q000009:adverse effects / Q000379:methods
D000911:Antibodies, Monoclonal; D003879:Dermatologic Agents; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha