Urease inhibitor from Datisca cannabina linn.
A new flavonoid datisdirin (1), along with eight known compounds tectochrysine, cearoin, sideroxyline, ursolic acid, corosolic acid, arjunolic acid, erythrodiol and oleanolic acid, were isolated from the ethyl acetate fraction of D. cannabina Linn. The structure of compound 1 was deduced on the basis of its spectral data. Datisdirin showed activity against the ureases enzyme.
Ahmad
Mansoor
M
Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan. herbalist51@yahoo.com
Muhammad
Noor
N
Ahmad
Manzoor
M
Arif Lodhi
Muhammad
M
Jehan
Noor
N
Khan
Zahid
Z
Ranjit
Rosa
R
Shaheen
Farzana
F
Iqbal Choudhary
Muhammad
M
D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D010940:Plant Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D014510:Urease / Q000037:antagonists & inhibitors*
D004791:Enzyme Inhibitors; D005419:Flavonoids; D010940:Plant Proteins; D014510:Urease