Tepid sponging plus dipyrone versus dipyrone alone for reducing body temperature in febrile children.
OBJECTIVE
The role of tepid sponging to promote fever control in children is controversial. We did not find any studies reporting on the effectiveness of tepid sponging in addition to dipyrone. The aim of this study was to compare the effects of tepid sponging plus dipyrone with dipyrone alone for reducing fever.


METHODS
A randomized clinical trial was undertaken at Instituto Materno-Infantil Professor Fernando Figueira, Recife, Pernambuco.


METHODS
Children from six months to five years old with axillary temperature greater than 38 masculineC in the emergency ward between January and July 2006 were eligible. One hundred and twenty children were randomly assigned to receive oral dipyrone (20 mg/kg) or oral dipyrone and tepid sponging for 15 minutes. The primary outcome was mean temperature reduction after 15, 30, 60, 90 and 120 minutes. Secondary outcomes were crying and irritability.


RESULTS
106 children finished the study. After the first 15 minutes, the fall in axillary temperature was significantly greater in the sponged group than in the control group (p < 0.001). From 30 to 120 minutes, better fever control was observed in the control group. Crying and irritability were observed respectively in 52% and 36% of the sponged children and in none and only two of the controls.


CONCLUSIONS
Tepid sponging plus dipyrone cooled faster during the first 15 minutes, but dipyrone alone presented better fever control over the two-hour period. Tepid sponging caused mild discomfort, crying and irritability for most of the children.


BACKGROUND
ACTRN12608000083392.
Alves
João Guilherme Bezerra
JG
Instituto Materno Infantil Professor Fernando Figueira, Recife, Pernambuco, Brazil. joaoguilherme@imip.org.br
Almeida
Natália Dornelas Câmara Marques de
ND
Almeida
Camila Dornelas Câmara Marques de
CD
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001494:Baths / Q000009:adverse effects; D001833:Body Temperature Regulation / Q000187:drug effects; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003448:Crying; D004177:Dipyrone / Q000627:therapeutic use*; D005260:Female; D005334:Fever / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004177:Dipyrone