[Urate urolithiasis: efficacy of combined treatment with trometamol compositum].
Contact dissolution of urate concrements was assessed in a direct action of the drug trometamol compositum on a concrement in combination with modem low-invasive technologies. A total of 67 patients with urate urolithiasis were divided into two groups: 44 patients of group 1 have undergone contact litholysis, 23 patients of group 2 have undergone extracorporeal shock-wave lithotripsy followed by contact litholysis. Dissolution was made with the drug trometamol compositum (Berlin-Chemie, Germany) delivered antegradely through nephrostomic drainage made previously. Other important components of litholysis consisted in low-intensive laser radiation and prophylactic antibacterial therapy. Positive results were achieved in all the patients. Mean litholysis duration was 4.8 +/- 1.8 days in group 1 and 1.09 +/- 0.29 days in group 2. Thus, high efficacy of the method is demonstrated.
V P
VP
Avdoshin
M I
MI
Andriukhin
E V
EV
Ol'shanskaia
D000328:Adult; D000368:Aged; D005079:Excipients / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D008096:Lithotripsy / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014325:Tromethamine / Q000008:administration & dosage*; D014527:Uric Acid; D052878:Urolithiasis / Q000188:drug therapy*
D005079:Excipients; D014325:Tromethamine; D014527:Uric Acid