Relationship between clinical, 24-hour, average day-time and night-time blood pressure and measures of arterial stiffness in essential hypertension.
Arterial wall stiffness is considered an independent cardiovascular risk factor. Aim of this study was to evaluate relationship between clinical, 24-hour, average day-time and night-time blood pressure (BP) and measures of arterial stiffness assessed by pulse wave velocity (PWV) (using SphygmoCor applanation tonometer) in essential hypertension (severe-resistant (RH, n=29) and moderate hypertension (EH, n=35)) and in normotensive control subjects (n-29) (NCS) matched by age. After multiple regression analysis, PWV remains significantly correlated mainly with night-time pulse pressure and to a lesser extent with age. PWV was significantly higher in RH compared to moderate EH and NCS.
Third Department of Internal Medicine, General Faculty Hospital, Prague, Czech Republic. janorosa@zoznam.sk
J
J
Rosa
B
B
Strauch
O
O
Petrák
T
T
Pikus
R
R
Holaj
T
T
Zelinka
D
D
Wichterle
J
J
Widimský
D000328:Adult; D001158:Arteries / Q000502:physiology / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology*; D016022:Case-Control Studies; D002940:Circadian Rhythm / Q000502:physiology*; D004548:Elasticity; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008875:Middle Aged; D009126:Muscle Relaxation / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology* / Q000503:physiopathology; D011673:Pulsatile Flow / Q000502:physiology; D012016:Reference Values