A new rearranged dolabellane diterpene from the soft coral Clavularia inflata.
A new dolabellane type diterpene 1 has been isolated through its acetate 1a. The structure of 1a was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by mass spectrometry. The structure of 1 was deduced by comparison of its NMR spectral data with those of 1a, while its relative stereochemistry was deduced by NOESY. The absolute stereochemistry of C-7 was determined by analyses of 1 separately esterified with R and S O-mandelic acids.
Chemistry Department, De La Salle University-Manila, Manila, 1004, Philippines.
Glenn V
GV
Alea
Bruce F
BF
Bowden
Consolacion Y
CY
Ragasa
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation
D004224:Diterpenes; C115566:dolabellane