Clindamycin-resistant Clostridium perfringens cellulitis.
Clostridium perfringens is responsible for a number of clinical conditions ranging from relatively mild food poisoning to the potentially life-threatening gas gangrene. Fortunately, C. perfringens has remained relatively susceptible to first line antibiotics in the treatment of soft tissue infection, however, the prevalence of antibiotic resistance is increasing amongst other anaerobic organisms. A case of anaerobic cellulitis caused by a clindamycin-resistant C. perfringens is described here, emphasising the emerging problem of antimicrobial resistance.
Department of Microbiology, Western Infirmary, Dumbarton Road, Glasgow G11 6NT, United Kingdom. nitish.khanna@nhs.net
Nitish
N
Khanna
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D002981:Clindamycin; D003016:Clostridium perfringens; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000382:microbiology; D003646:Debridement; D024881:Drug Resistance, Bacterial; D005738:Gas Gangrene / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D015995:Prevalence; D017592:Skin Care / Q000379:methods; D013492:Suppuration; D013848:Thigh; D014945:Wound Healing
D000900:Anti-Bacterial Agents; D002981:Clindamycin