Copper(II)-catalyzed exo and enantioselective cycloadditions of azomethine imines.
A strategy for exo and enantioselective 1,3-dipolar cycloaddition of azomethine imines to 2-acryloyl-3-pyrazolidinone is described. The corresponding cycloadducts are isolated with high diastereoselectivities (up to >96:4 exo/endo) and enantioselectivities (up to 98% ee).
Department of Chemistry, North Dakota State University, Fargo, North Dakota 58105, USA. mukund.sibi@ndsu.edu
Mukund P
MP
Sibi
Digamber
D
Rane
Levi M
LM
Stanley
Takahiro
T
Soeta