Successful treatment of pituitary abscess with oral administration of sparfloxacin.
Pituitary abscess is a rare infection and it is difficult to make the correct diagnosis. It is usually treated by a combination of surgical drainage and intravenous administration of antibiotics. We describe a 74-year-old woman with recurrent meningo-encephalitis due to pituitary abscess. The abscess increased in size in spite of the intravenous administration of panipenem/betamipron (PAPM/BP), clindamycin (CLDM) and chloramphenicol (CP). Finally she was successfully treated with oral administration of sparfloxacin (SPFX) without operation.
Uchida
Yujiro
Y
Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka. uchy@cclm.med.kyushu-u.ac.jp
Tsuchimochi
Noriko
N
Oku
Miwako
M
Fujihara
Naoko
N
Shimono
Nobuyuki
N
Okada
Kaoru
K
Harada
Mine
M
D000284:Administration, Oral; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001922:Brain Abscess / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D024841:Fluoroquinolones / Q000008:administration & dosage*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016920:Meningitis, Bacterial / Q000188:drug therapy* / Q000209:etiology; D010900:Pituitary Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; C061363:sparfloxacin