Minor iridoids from the roots of Valeriana wallichii.
Four new iridoids, valeriotetrates B and C (1 and 2), 8-methylvalepotriate (3), and 1,5-dihydroxy-3,8-epoxyvalechlorine A (4), together with three known iridoids, were isolated from the roots of Valeriana wallichii. The structures of the new compounds were elucidated by analysis of 1D and 2D NMR and HRESIMS data. Compound 4 is an unusual iridoid bearing a C-10 chloro group and an oxo bridge connecting C-3 and C-8, resulting in a rigid skeleton.
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.
Rui
R
Wang
Dan
D
Xiao
Yan-Hong
YH
Bian
Xiao-Yue
XY
Zhang
Bang-Jing
BJ
Li
Li-Sheng
LS
Ding
Shu-Lin
SL
Peng
D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014632:Valerian / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D039823:Iridoids