4 Hz magnetic field decreases oxidative stress in mouse brain: a chemiluminescence study.
We investigated the effects of delta and theta brain wave frequency magnetic fields (3, 4, and 5) on mouse brain by detecting photonic oxidative stress makers; spontaneous photon emission (SPE) and lucigenin and tert-butyl hydroperoxide (TBHP) induced chemiluminescences (CL). For this purpose, Balb/C mice were exposed to 3, 4, and 5 Hz magnetic fields (MF) at 0.7 mT for 3 h, respectively. After that we monitored SPE and lucigenin and TBHP-induced CL of the homogenates of mice brains. There was a significant decrease in SPE in the 4 Hz MF-exposed group. Lucigenin-induced CL was also significantly decreased only in the 4 Hz MF-exposed group. TBHP-induced CL was also distinctively decreased by all frequencies, 3, 4, and 5 Hz MF exposures. These results showed that oxidative stress in a mouse brain was decreased by 4 Hz MF. We suggest that the application of 4 Hz MF will contribute to magnetic field therapy.
Park
Won-Hee
WH
Laboratory of Hygienic Pharmacy, College of Pharmacy, Sookmyung Women's University, Seoul, Korea.
Soh
Kwang-Sup
KS
Lee
Byung-Cheon
BC
Pyo
Myoung-Yun
MY
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields; D008163:Luminescent Measurements; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D018384:Oxidative Stress / Q000502:physiology* / Q000528:radiation effects*; D011829:Radiation Dosage; D017382:Reactive Oxygen Species / Q000378:metabolism*
D017382:Reactive Oxygen Species