Development of maxillary accessory ostium following sinusitis in rabbits.
OBJECTIVE
Maxillary accessory ostium is one of the anatomical variations that may play a role in the development of chronic maxillary sinusitis. Although some authors claim that accessory ostia develop following acute maxillary sinusitis, it is not clear whether they are congenital or acquired.


METHODS
Animal experimental study.


METHODS
Ten New Zealand type rabbits were used in the study. In phase 1, lateral nasal walls of five New Zealand type rabbits were examined for the presence of natural and accessory ostia of the maxillary sinus and any area resembling fontanelles in humans. In phase 2, experimental sinusitis was induced in the right sides of the other five rabbits. Following sacrifice, lateral nasal walls were examined for the development of accessory ostia.


RESULTS
Six of the ten sides of phase 1 animals contained a membranous part in the medial wall of the maxillary sinus resembling the fontanelles in humans (60%). None of them had an accessory maxillary ostium. Accessory ostia developed in two of the five sides with sinusitis (40%).


CONCLUSIONS
We have shown for the first time that accessory maxillary ostia develop following experimental sinusitis in rabbits. Further studies in humans are indicated.
Genc
Selahattin
S
Kecioren Education and Research Hospital ENT Clinic, Ankara, Turkey.
Ozcan
Muge
M
Titiz
Ali
A
Unal
Adnan
A
D000818:Animals; D004195:Disease Models, Animal; D005557:Formaldehyde; D008443:Maxillary Sinus / Q000473:pathology*; D015523:Maxillary Sinusitis / Q000209:etiology* / Q000473:pathology*; D009079:Mucociliary Clearance; D009297:Nasal Mucosa / Q000473:pathology; D011008:Pneumococcal Infections / Q000473:pathology*; D011142:Polyvinyl Alcohol; D011817:Rabbits; D013630:Tampons, Surgical
D005557:Formaldehyde; C027490:polyvinyl alcohol formaldehyde foam; D011142:Polyvinyl Alcohol