The first 5 minutes after greater occipital nerve block.
We performed greater occipital nerve blocks on 24 migraineurs with unilateral migraine and trigeminal nerve distribution allodynia. Using a visual analog scale for migraine pain, brush allodynia in the trigeminal nerve distribution and photophobia were reduced 64%, 75%, and 67%, respectively, after 5 minutes. Allodynia improved faster than headache. The results of this study suggest that greater occipital nerve blocks initiate an inhibitory process that shuts down several symptom generators.
Young
William
W
Thomas Jefferson University-Neurology, Philadelphia, PA 19107, USA.
Cook
Brianna
B
Malik
Shahram
S
Shaw
James
J
Oshinsky
Michael
M
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology / Q000628:therapy; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement / Q000187:drug effects / Q000379:methods; D013127:Spinal Nerves / Q000187:drug effects / Q000502:physiology; D013997:Time Factors; D014276:Trigeminal Nerve / Q000187:drug effects / Q000502:physiology; D055815:Young Adult