Inaccurate hemoglobin A(1C) levels in patients with type 1 diabetes and hereditary persistence of hemoglobin F.
We report 2 African-American boys with type 1 diabetes and hereditary persistence of hemoglobin F. The diagnosis came to light after both patients exhibited inconsistent hemoglobin A(1C) (HbA(1C)) levels with respect to serum glucose measurements. This demonstrates the importance of frequent glucose monitoring and interpreting the HbA(1C) level in light of serum glucose measurements.
Felner
Eric I
EI
Department of Pediatrics, Division of Endocrinology, Emory University School of Medicine, Atlanta, GA, USA. efelner@emory.edu
McGrath
Maureen
M
D001774:Blood Chemical Analysis / Q000379:methods; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D002648:Child; D015897:Comorbidity; D048909:Diabetes Complications / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000175:diagnosis*; D005319:Fetal Hemoglobin / Q000096:biosynthesis*; D019270:Fructosamine / Q000097:blood; D020022:Genetic Predisposition to Disease; D005947:Glucose / Q000378:metabolism; D006442:Glycated Hemoglobin / Q000096:biosynthesis*; D006453:Hemoglobinopathies / Q000097:blood / Q000150:complications; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male
D001786:Blood Glucose; D005319:Fetal Hemoglobin; D019270:Fructosamine; D005947:Glucose; D006442:Glycated Hemoglobin; D007328:Insulin