Diagnostic value of lumbar puncture in afebrile infants with suspected new-onset seizures.
No established guidelines address the need for lumbar puncture in fever-free infants younger than 6 months of age with a first seizure. We analyzed cerebrospinal fluid results in infants and found that lumbar puncture adds little diagnostic value to the evaluation of young, well-appearing infants presenting with possible new-onset seizures.
Department of Neurology, Children's National Medical Center and George Washington University School of Medicine, Washington, DC, USA.
Tarannum M
TM
Lateef
Tammy N
TN
Tsuchida
Taeun
T
Chang
Jami
J
Johnson
William D
WD
Gaillard
Karin B
KB
Nelson
D003937:Diagnosis, Differential; D004827:Epilepsy / Q000134:cerebrospinal fluid / Q000175:diagnosis; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007958:Leukocyte Count; D009504:Neutrophils / Q000166:cytology; D010372:Pediatrics / Q000379:methods; D011446:Prospective Studies; D012640:Seizures / Q000134:cerebrospinal fluid* / Q000175:diagnosis*; D013129:Spinal Puncture; D013997:Time Factors
D005947:Glucose