Clinical and laboratory profile of patients with tuberculosis/HIV coinfection at a national referral centre: a case series.
This case series describes the clinical and laboratory profile of 15 patients with tuberculosis (TB) HIV coinfection admitted to a referral centre in the Islamic Republic of Iran. Most of the patients (13) were male; the mean age was 36.9 years. Intravenous drug use was the route of transmission for all males and heterosexual intercourse for the 2 females; 12 patients had a history of imprisonment. All patients had pulmonary TB; 13 were smear-positive and all except 1 had atypical radiological presentation. Drug-induced hepatitis occurred in 3 patients and 12 had hepatitis C coinfection. Five patients died. The mean CD4 count was 229.2 (SD 199.5) cells/mm3 and 78.6% had CD4 count < 350. TB may be an AIDS-defining illness in this country.
Tabarsi
P
P
National Research Institute of Tuberculosis and Lung Disease, Tehran, Islamic Republic of Iran. tabarsi@nritld.ac.ir
Mirsaeidi
S M
SM
Amiri
M
M
Mansouri
S D
SD
Masjedi
M R
MR
Velayati
A A
AA
D017088:AIDS-Related Opportunistic Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D000328:Adult; D017677:Age Distribution; D018791:CD4 Lymphocyte Count; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006526:Hepatitis C / Q000453:epidemiology; D006786:Hospitals, Urban; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011329:Prisoners / Q000706:statistics & numerical data; D012017:Referral and Consultation; D012307:Risk Factors; D017678:Sex Distribution; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000150:complications; D011795:Surveys and Questionnaires; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*