Stress-associated or functional hypothalamic amenorrhea in the adolescent.
Stress-associated amenorrhea in the adolescent is likely similar to the disorder found in young reproductive-aged adults and is termed hypothalamic amenorrhea. The key defect is an abnormality in the secretion of gonadotropin-releasing hormone. This review examines the current studies that characterize the disorder and the plausible factor(s) that may account for the disturbances in gonadotropin-releasing hormone, and identifies directions for future research in this group of disorders.
Department of Reproductive Biology, Case Western Reserve School of Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, MAC 7105, Cleveland, OH 44106-5034, USA. James.Liu@case.edu
James H
JH
Liu
Arthur H
AH
Bill
D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D005260:Female; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology* / Q000503:physiopathology; D010913:Pituitary-Adrenal System / Q000502:physiology* / Q000503:physiopathology; D013315:Stress, Psychological / Q000150:complications*; D013961:Thyroid Gland / Q000502:physiology* / Q000503:physiopathology