Histological aspects of rhinosinusal polyps.
Contemporary cohort cross-sectional study.


BACKGROUND
Despite its importance for an accurate diagnosis, histology differences among nasal polyps and its clinical implications are rarely reported in the literature. The existing papers classify polyp samples without concern for prior treatments, which could influence the results attained.


OBJECTIVE
carry out a morphological study, through light microscopy, of nasal polyps' structural alterations in the absence of any type of prior treatment and histologically classify it in relation to studies published in the literature.


METHODS
We studied 89 patients with nasosinusal polyps without prior treatment. Polyp samples were collected by outpatient biopsy and analyzed through light microscopy after dyeing with hematoxylin-eosin.


RESULTS
Samples were classified in the following way: Edematous or eosinophilic polyp 65 cases (73%); fibro-inflammatory polyp: 16 cases (18%); Polyp with Sero-mucinose gland hyperplasia: 06 cases (6.7%) and polyp with stroma atypia: 2 cases (2.3%).


CONCLUSIONS
eosinophilic pattern prevailed in the patients with nasosinusal polyps of the population studied. This pattern is similar to the ones found in the major studies, which, however, do not mention prior treatment.


CONCLUSIONS
after analyzing the polyps' histological characteristics, we noticed that the untreated polyps present a predominantly eosinophilic pattern.
Luciano Gustavo Ferreira
LG
Couto
Atílio Maximino
AM
Fernades
Daniel Ferracioli
DF
Brandão
Dalisio de
Dd
Santi Neto
Fabiana Cardoso Pereira
FC
Valera
Wilma T
WT
Anselmo-Lima
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D016009:Chi-Square Distribution; D015331:Cohort Studies; D004396:Coloring Agents; D003430:Cross-Sectional Studies; D004802:Eosinophilia / Q000473:pathology; D005260:Female; D006416:Hematoxylin; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000145:classification / Q000648:ultrastructure*; D010254:Paranasal Sinus Diseases / Q000473:pathology*; D010256:Paranasal Sinuses / Q000648:ultrastructure*
D004396:Coloring Agents; D006416:Hematoxylin