Late widespread skeletal metastases from myxoid liposarcoma detected by MRI only.
BACKGROUND
Myxoid liposarcoma is the second most commonly occurring sub-type of liposarcomas. In contrast to other soft tissue sarcomas, it is known to have a tendency to spread toward extrapulmonary sites, such as soft tissues, retroperitoneum, and the peritoneal surface. Bony spread, however, is not as common.


METHODS
We report an unusual case of diffuse skeletal metastases from myxoid liposarcoma occurring 13 years after treatment of the primary tumour in the left lower limb. The skeletal spread of the disease was demonstrated on MRI only after other imaging modalities (plain radiography, CT and TC99 bone scans) had failed to detect these metastases.


CONCLUSIONS
MRI is an extremely sensitive and specific screening tool in the detection of skeletal involvement in these types of sarcomas, and therefore, should be a part of the staging process.
London Bone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK. sammyhanna@hotmail.com
Sammy A
SA
Hanna
Yassar A
YA
Qureshi
Lee
L
Bayliss
Lee A
LA
David
Paul
P
O'Donnell
Ian R
IR
Judson
Timothy W R
TW
Briggs
D006801:Humans; D018208:Liposarcoma, Myxoid / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000209:etiology / Q000556:secondary*; D018482:Muscle, Skeletal / Q000473:pathology*