Convenient preparations of azo-dye labeled amino acids and amines.
N-(4-Arylazobenzoyl)-1H-benzotriazoles 3 react with amino acids 4 and amines 6 to give azo-dye labeled amino acids (5a-m) and amines (7a-n) in high yields (74-100%) with retention of chirality.
Katritzky
Alan Roy
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
Chen
Qi-Yin
QY
Tala
Srinivasa Rao
SR
D000588:Amines / Q000032:analysis / Q000737:chemistry*; D000596:Amino Acids / Q000032:analysis / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D004396:Coloring Agents / Q000737:chemistry*; D013194:Staining and Labeling / Q000379:methods*; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry
D000588:Amines; D000596:Amino Acids; D001391:Azo Compounds; D002264:Carboxylic Acids; D004396:Coloring Agents; D014230:Triazoles