Accurate non-invasive determination of pKa of surface functionalised ion exchange monoliths using capacitively coupled contactless conductivity detection.
The use of on-column capacitively coupled contactless conductivity detection for the accurate non-invasive visualisation of the pH dependence of covalently bound boronic acid groups within a monolithic polymeric capillary column is demonstrated.
Centre for Bioanalytical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.
Eoin
E
Gillespie
Damian
D
Connolly
Pavel N
PN
Nesterenko
Brett
B
Paull
D001897:Boronic Acids / Q000737:chemistry; D004553:Electric Conductivity; D004563:Electrochemistry; D019075:Electrophoresis, Capillary / Q000379:methods*; D007474:Ion Exchange
D001897:Boronic Acids