Filtering bleb rupture after intravitreal triamcinolone acetonide injection.
Intravitreal triamcinolone acetonide is effective in treating various ocular disorders associated with inflammation and swelling of the retina. Unfortunately, the use of intraocular steroids is also associated with several side effects, including increased intraocular pressure and the development of cataracts. This article describes a case of intravitreal steroid injection resulting in filtering bleb rupture due to an acute rise of intraocular pressure, expands on the mechanism, and provides possible ways to avoid such an occurrence in thin, cystic filtering blebs.
Kahook
Malik Y
MY
UPMC Eye Center, Eye and Ear Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Noecker
Robert J
RJ
Abdelghani
Wael M
WM
Schuman
Joel S
JS
D000368:Aged; D003228:Conjunctiva / Q000293:injuries*; D005260:Female; D018463:Filtering Surgery; D019793:Fluorescein; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects; D008269:Macular Edema / Q000188:drug therapy / Q000209:etiology; D012170:Retinal Vein Occlusion / Q000150:complications; D012421:Rupture; D013529:Surgical Wound Dehiscence / Q000175:diagnosis / Q000209:etiology*; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014822:Vitreous Body
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D019793:Fluorescein