The risks and benefits of searching for incidental findings in MRI research scans.
We weigh the presumed benefits of routinely searching all research scans for incidental findings (IFs) against its substantial risks, including false-positive and false-negative findings, and the possibility of triggering unnecessary, costly evaluations and perhaps harmful treatments. We argue that routinely searching for IFs may not maximize benefits and minimize risks to participants.
Royal
Jason M
JM
City University of New York, USA.
Peterson
Bradley S
BS
D000328:Adult; D035843:Biomedical Research / Q000941:ethics*; D001927:Brain Diseases / Q000175:diagnosis*; D003951:Diagnostic Errors; D030881:Disclosure / Q000941:ethics*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D035842:Research Subjects; D018570:Risk Assessment