Nonseminomatous germ cell tumor of the testis 9 years after a germ cell tumor of the pineal gland: case report and review of the literature.
Extragonadal germ cell tumors are extremely rare and account for only 3%-5% of all germ cell tumors. These tumors are rarely associated with metachronous primary testicular germ cell tumors. We report the fourth case of a primary germ cell tumor occurring after the treatment of a primary CNS germ cell tumor in a 27 year-old male with embryonal cell carcinoma of the testicle 9 years after the treatment of a germ cell tumor of the pineal gland. This represents the first case of a non-seminomatous germ cell tumor of the testicle after a CNS germ cell tumor. This case illustrates the importance of long term follow-up and self-examination in patients with extragonadal germ cell tumors.
Department of Urology, Temple University Hospital, Philadelphia, Pennsylvania 19140, USA.
Jason
J
Rothman
Richard E
RE
Greenberg
William I
WI
Jaffe
D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy; D018236:Carcinoma, Embryonal / Q000473:pathology; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology / Q000628:therapy; D016609:Neoplasms, Second Primary / Q000473:pathology; D010870:Pineal Gland; D013736:Testicular Neoplasms / Q000473:pathology