Fetal sex and maternal asthma control in pregnancy.
Asthma is a prevalent chronic disorder that might substantially complicate pregnancy. Some recent reports suggest that the presence of a female fetus might be associated with worse maternal asthma symptoms during pregnancy. We tested this hypothesis using the sample of 719 pregnant women with asthma prospectively enrolled in the OTIS study. The presence of a female fetus was associated with a higher incidence of hospitalizations for asthma during pregnancy (OR = 1.84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations.
Bakhireva
Ludmila N
LN
Division of Pharmacy Practice and Department of Family/Community Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Schatz
Michael
M
Jones
Kenneth Lyons
KL
Tucker
Carey M
CM
Slymen
Donald J
DJ
Klonoff-Cohen
Hillary S
HS
Gresham
Louise
L
Johnson
Diana
D
Chambers
Christina D
CD
D000328:Adult; D000704:Analysis of Variance; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005333:Fetus; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008137:Longitudinal Studies; D008429:Maternal Welfare; D015999:Multivariate Analysis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods / Q000706:statistics & numerical data*; D018570:Risk Assessment; D012727:Sex Characteristics; D012732:Sex Determination Analysis; D016896:Treatment Outcome
D018927:Anti-Asthmatic Agents