Fetal sex and maternal asthma control in pregnancy.
Asthma is a prevalent chronic disorder that might substantially complicate pregnancy. Some recent reports suggest that the presence of a female fetus might be associated with worse maternal asthma symptoms during pregnancy. We tested this hypothesis using the sample of 719 pregnant women with asthma prospectively enrolled in the OTIS study. The presence of a female fetus was associated with a higher incidence of hospitalizations for asthma during pregnancy (OR = 1.84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations.
Division of Pharmacy Practice and Department of Family/Community Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Ludmila N
LN
Bakhireva
Michael
M
Schatz
Kenneth Lyons
KL
Jones
Carey M
CM
Tucker
Donald J
DJ
Slymen
Hillary S
HS
Klonoff-Cohen
Louise
L
Gresham
Diana
D
Johnson
Christina D
CD
Chambers
D000328:Adult; D000704:Analysis of Variance; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005333:Fetus; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008137:Longitudinal Studies; D008429:Maternal Welfare; D015999:Multivariate Analysis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods / Q000706:statistics & numerical data*; D018570:Risk Assessment; D012727:Sex Characteristics; D012732:Sex Determination Analysis; D016896:Treatment Outcome
D018927:Anti-Asthmatic Agents