Correlation of antimüllerian hormone and baseline follicle-stimulating hormone levels.
OBJECTIVE
To compare how a given level of antimüllerian hormone (AMH) might be used to predict the level of FSH.


METHODS
Retrospective cohort study.


METHODS
Academically affiliated private fertility center.


METHODS
Eighty-one women in preparation for an IVF cycle.


METHODS
None.


METHODS
Levels of FSH and AMH before start of ovulation induction.


RESULTS
Serum AMH and log-converted FSH levels were negatively correlated (R(2) = 0.42). The linear regression model for FSH, based on random AMH, was as follows: LnFSH = 2.3 + -0.25 x lnAMH; 95% confidence limits of the coefficient 0.-32 to 0.-18, suggesting that an AMH level of 0.5 ng/mL is predictive of a baseline FSH level of 12.1 mIU/mL (95% confidence interval 11.4-12.7 mIU/mL).


CONCLUSIONS
These data demonstrate a statistical association between FSH and AMH in assessing ovarian reserve. Using FSH and AMH in combination may improve the evaluation of ovarian reserve. However, it remains to be determined which of these two ovarian function parameters is superior in assessing ovarian reserve with a single test and which test, or combination of tests, will in the future be used in routine infertility evaluations.
Singer
Tomer
T
Department of Obstetrics and Gynecology, Lenox Hill Hospital, New York, NY, USA.
Barad
David H
DH
Weghofer
Andrea
A
Gleicher
Norbert
N
D000328:Adult; D000375:Aging; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015331:Cohort Studies; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D010053:Ovary / Q000502:physiology*; D010062:Ovulation Induction; D012189:Retrospective Studies
D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone