[Comparison of midazolam and propofol as conscious sedation in oocyte retrieval of IVE-ET].
To compare the efficacy and safety of midazolam combined with fentanyl and propofol combined with fentanyl as conscious sedation in oocyte retrieval of in vitro fertilization and embryo transplantation (IVF-ET).



Eighty patients receiving IVE-ET were randomly divided into midazolam combined with fentanyl group (midazolam group) and propofol combined with fentanyl group (propofol group). Antalgic effects, circulation status (blood pressure, heart rate), respiration status (rate, oxygen saturation and respiration depression) during operation, nausea and vomiting, and amnestic effects after operation were compared.



No differences of antalgic effects and circulation status between two groups were observed. Percentages of respiration depression,vomiting and amnesia of midazolam group were 5.0 %, 10.0 % and 25%, respectively, and those of propofol group were 25%, 27.5% and 7.5%, respectively, which had statistical significance.



As conscious sedation, midazolam combined with fentanyl is better than propofol combined with fentanyl in oocyte retrieval of IVF-ET.
The Affiliated Obstetrics and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Yuan-Ying
YY
Ma
Yan
Y
Shen
Li-San
LS
Zhang
D000328:Adult; D019162:Anesthetics, Combined / Q000008:administration & dosage; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D005307:Fertilization in Vitro; D006801:Humans; D008874:Midazolam / Q000008:administration & dosage*; D054315:Oocyte Retrieval / Q000379:methods*; D015742:Propofol / Q000008:administration & dosage*
D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol