Experimental design for parameter estimation from batch culture.
An experimental design to estimate the parameters in a Monod-type equation from batch culture data was examined. Consideration was given to the design of experiments to estimate accurate values of the parameters. Sequential experimental design with the information index was used for this purpose. With this approach the standard deviation of the parameter values was reduced using simulated batch culture data.
Yoo
Y J
YJ
Department of Chemical and Nuclear Engineering, University of Maryland, College Park, Maryland 20742.
Marino-Galarraga
M
M
Hong
J
J
Hatch
R T
RT