Determination of reactor biomass by acoustic resonance densitometry.
Acoustic resonance densitometry (ARD) is reported as a method suitable not only for precise investigations into changes of specific gravity in bioreactor media but also as a technique able to provide an accurate wide range and direct determination of cellular mass in fermentation processes. It is further shown that this method can replace present optical procedures, minimizing dilution errors and operator involvement and is suitable for development as an on-line biomass monitoring system.
Biosensor Group, Microbial Technology Laboratory, Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, England SP4 OJG.
B C
BC
Blake-Coleman
D J
DJ
Clarke
M R
MR
Calder
S C
SC
Moody