Frequency of celiac disease is not increased among multiple sclerosis patients.
We evaluated the presence of IgA and IgG celiac disease-related antibodies in a sample of 217 patients with multiple sclerosis (MS) and in a sample of 200 controls not affected by neurological disorders. None of the 217 patients with MS presented IgG and IgA anti-gliadin, anti-endomysial antibodies, anti-tissue transglutaminase and anti-reticulin, whereas only one of the selected controls presented specific antibodies; this subject resulted to be effectively affected by celiac disease. Our data did not show an increased frequency of celiac disease among patients with MS.
Nicoletti
A
A
Dipartimento di Neuroscienze, Università di Catania, Via Santa Sofia no. 78, Catania, Italy.
Patti
F
F
Lo Fermo
S
S
Sciacca
A
A
Laisa
P
P
Liberto
A
A
Lanzafame
S
S
Contraffatto
D
D
D'Agate
C
C
Russo
A
A
Zappia
M
M
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D044182:Benzylisoquinolines / Q000276:immunology; D002446:Celiac Disease / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D005903:Gliadin / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000276:immunology; D016036:Seroepidemiologic Studies; D011503:Transglutaminases / Q000276:immunology
D001323:Autoantibodies; D044182:Benzylisoquinolines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D005903:Gliadin; D011503:Transglutaminases; C003298:reticuline