[Sinusitis--judicious antibiotic treatment].
The paper presents different forms of sinusitis in children and adults as well as the patomechanism of sinusitis of infective and non-infective origin. The role of bacterial infection has been discussed. Participation of major pathogens of URTI such as S. pneumoniae, H. influenzae and M. catarrhalis has been highlighted and the factors influencing growth of their antibiotic-resistant stains. Guidelines concerning antibiotic therapy in children and adults, depending on disease course, age and factors influencing growth of resistant stains have been presented. Causes of failure in treatment of sinusitis have been analysed eg. in case of bacterial biofilm growth or non-neutrophilic inflammation forms. Antimicrobial treatment concerns mainly acute and aggravated infections. In case of chronic sinusitis, antibiotic therapy is complementary to surgical treatment.
Niedzielska
Grazyna
G
Katedra i Klinika Otolaryngologii Dzieciecej, Foniatrii i Audiologii AM w Lublinie.
D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D012852:Sinusitis / Q000188:drug therapy* / Q000382:microbiology / Q000821:virology; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents