Avian myeoloblastosis virus (AMV): only one side of the coin.
For many years, scientists and suppliers have refered to AMV-RT as the reverse transcriptase produced by the Avian Myelobalstosis Virus. This manuscript briefly reviews the molecular basis for biological dependence of AMV for the envelope and RT proteins that are produced by its natural helper the Myeloblastosis Associated Virus (MAV). Because the wide use of the term <<AMV RT>> obscures scientific facts, it is worthwhile to clarify this issue for the scientific community, especially for younger scientists who might not be aware of the functional relationships that exist between these two viruses.
Department of Dermatology, University of Michigan Medical School, 1150 W, Medical Center Dr,, Medical Science I, Room 6447, Ann Arbor, Michigan 48109-0609, USA. bperbal@free.fr
Bernard
B
Perbal
D009189:Avian Myeloblastosis Virus / Q000502:physiology*; D006378:Helper Viruses / Q000201:enzymology*; D012194:RNA-Directed DNA Polymerase / Q000235:genetics / Q000378:metabolism*; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*
D014764:Viral Proteins; D012194:RNA-Directed DNA Polymerase