[Biological response modifiers in the treatment of immunoinflammatory diseases].
Biological response modifiers are modified (poly) peptides from living organisms designed to modulate a specific biologic process. Biotechnology has led to the rapid development of recombinant drugs for treatment of many immunoinflammatory diseases. In this article, we briefly describe the main types of these therapeutic proteins, their mechanisms of action and side-effects.
Skov
Lone
L
Gentofte Hospital, Dermatologisk Afdeling, Hellerup. lskov@dadlnet.dk
Bendtzen
Klaus
K
D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use*; D001327:Autoimmune Diseases / Q000188:drug therapy*; D016207:Cytokines / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use*; D007249:Inflammation / Q000188:drug therapy*; D036341:Intercellular Signaling Peptides and Proteins / Q000009:adverse effects / Q000627:therapeutic use*; D011993:Recombinant Fusion Proteins / Q000009:adverse effects / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D016207:Cytokines; D007155:Immunologic Factors; D036341:Intercellular Signaling Peptides and Proteins; D011993:Recombinant Fusion Proteins