[The prevalence of metabolic syndrome and related factors in patients with schizophrenia].
OBJECTIVE
The aim of this study was to examine the prevalence of metabolic syndrome (MS) and related factors in patients with schizophrenia at an outpatient clinic.


METHODS
All 108 patients with schizophrenia or schizoaffective disorder that presented to the outpatient clinic between 12 May and 12 June 2006 were included in the study. Of the 108 patients, 100 whose biochemical analyses were completed were assessed.


RESULTS
The prevalence of MS was 21%, 34%, and 41% according to ATP III, ATP III-A, and IDF criteria, respectively. Increased waist circumference and low HDL level were frequent among the patients. The prevalence of MS increased with age. Mean age, duration of illness and duration of treatment were higher and family history of obesity was common in the patients with MS.


CONCLUSIONS
The prevalence of ATP III-defined MS in patients with schizophrenia was lower compared to that reported in other studies; however, the prevalence of MS was high based on ATP III-A and IDF criteria. Patients with schizophrenia are at increased risk for MS or related metabolic problems. In particular, when risk factors such as older age, female gender, long duration of illness and treatment, and family history of obesity exist, clinicians should examine the metabolic condition of the patient. Increased waist circumference and low HDL level are probably the best predictors of MS.
Haydarpaşa Numune Eğitim ve Araştirma Hastanesi Psikiyatri Kl., Istanbul. cemcerit@yahoo.com
Cem
C
Cerit
Eylem
E
Ozten
Mustafa
M
Yildiz
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001786:Blood Glucose; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications*; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications*; D014280:Triglycerides / Q000097:blood; D014421:Turkey / Q000453:epidemiology
D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides