Organ preservation surgery for laryngeal cancer.
The advent of combined chemotherapy and radiation protocols in the treatment of laryngeal cancer has given rise to the term "organ preservation." Open organ preservation surgical procedures for laryngeal cancer and their indications for use are reviewed. Principles involved in organ preservation laryngeal surgery and how they relate to evaluating and confidently selecting surgical candidates are discussed. Because total laryngectomy and medical organ preservation protocols may not be acceptable to the patient from a quality of life standpoint, the authors emphasize that it is incumbent upon the head and neck surgeon to have a thorough understanding of all options available for treatment in the organ preservation paradigm for laryngeal cancer to provide the best oncologic and functional outcome.
Tufano
Ralph P
RP
Department of Otolaryngology - Head and Neck Surgery, 6th Floor Johns Hopkins Outpatient Center, 601 N. Caroline Street, Baltimore, MD 21287, USA. rtufano@jhmi.edu
Stafford
Edward M
EM
D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D007828:Laryngoscopy; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D016879:Salvage Therapy / Q000379:methods