Acute actinic cheilitis-like chemical irritant reaction following accidental contact with ethylene glycol-favorable response to topical 1% pimecrolimus cream: a case report.
Ethylene glycol is a colorless, odorless, nonvolatile, water-soluble fluid, mainly used as automobile antifreeze and coolant. This substance is a frequent culprit in accidental and intentional poisonings. Although potentially fatal systemic consequences of ethylene glycol ingestion are well known, local adverse effects through brief skin and mucosa contact with ethylene glycol have been rarely reported. Herein we report a patient with accidental ethylene glycol contact to the lower lip, who presented with acute, manifest, actinic cheilitis-like chemical irritant reaction and favorably responded to topical pimecrolimus 1% cream.
Department of Dermatology, Yeditepe University School of Medicine, Istanbul, Turkey. emelerkek@hotmail.com
Emel
E
Erkek
Mustafa
M
Kazkayasi
Onder
O
Bozdogan
D000059:Accidents; D000287:Administration, Topical; D002613:Cheilitis / Q000139:chemically induced* / Q000188:drug therapy; D019855:Ethylene Glycol / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008046:Lip / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D016559:Tacrolimus / Q000031:analogs & derivatives* / Q000627:therapeutic use
D007166:Immunosuppressive Agents; C117268:pimecrolimus; D019855:Ethylene Glycol; D016559:Tacrolimus