Secondary metabolites from Tectona philippinensis.
The air-dried leaves of Tectona philippinensis, an endemic and endangered Philippine medicinal plant, afforded 5-hydroxy-3,7,4'-trimethoxyflavone (1), 5,4'-dihydroxy-3,7-dimethoxyflavone (2), squalene (3), a mixture of lupeol (4a) and beta-amyrin (4b), chlorophyllide a (5), and hydrocarbons. Antimicrobial tests on 1 and 2 indicated low antifungal activity against the fungi, Candida albicans and Trichophyton mentagrophytes. Compound 1 was also found to have low antibacterial activity against Escherichia coli and Pseudomonas aeruginosa.
Ragasa
Consolacion Y
CY
Chemistry Department, De La Salle University, 1004 Manila. ragasac@dlsu.edu.ph
Lapina
Maria Claribel
MC
Lee
Jadz Jevz
JJ
Mandia
Emelina H
EH
Rideout
John A
JA
D002735:Chlorophyllides / Q000302:isolation & purification; D047309:Flavones / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification*; D029648:Verbenaceae / Q000737:chemistry*
D002735:Chlorophyllides; D047309:Flavones; D014315:Triterpenes; C034388:chlorophyllide a