Macrophages and dendritic cells: what is the difference?
Segerer et al. report the expression and localization of macrophage and dendritic-cell markers in human renal biopsies and indicate that both cell types express CD68, findings that resonate with murine studies. The functional and phenotypic distinction between macrophages and dendritic cells is discussed.
Phagocyte Laboratory, Medical Research Council Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
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Ferenbach
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Hughes
D000954:Antigens, Surface / Q000032:analysis; D015415:Biomarkers / Q000032:analysis; D003713:Dendritic Cells / Q000737:chemistry* / Q000502:physiology; D006801:Humans; D016130:Immunophenotyping; D007668:Kidney / Q000166:cytology; D007674:Kidney Diseases / Q000276:immunology; D008264:Macrophages / Q000737:chemistry* / Q000502:physiology
D000954:Antigens, Surface; D015415:Biomarkers