[Pathology of primary tumours of the pleura].
In the WHO classification, pleural tumours of mesothelial and mesenchymal origin as well as lymphoproliferative disorders are distinguished, with malignant mesotheliomas forming the most common primary pleural tumour. Histologically, a prognostically relevant differentiation between epitheloid (40-60 %), sarcomatoid (20-30 %), and biphasic mesotheliomas (20-30 %) is made. Besides other rare primary tumours of the pleura, the differential diagnoses of malignant mesotheliomas comprise carcinomatous pleuritis of intra- and extrapulmonary malignancies. Especially in early tumour stages, the differentiation from reactive pleural changes requires a close interdisciplinary cooperation with a careful correlation between histopathological findings and clinical presentation.
Zentrum für Pathologie, Klinikum Bremen-Mitte, Bremen. klaus.junker@klinikum-bremen-mitte.de
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D018254:Adenomatoid Tumor; D003937:Diagnosis, Differential; D006801:Humans; D008654:Mesothelioma / Q000145:classification / Q000473:pathology*; D009367:Neoplasm Staging; D010994:Pleura / Q000473:pathology; D016066:Pleural Effusion, Malignant / Q000473:pathology; D010997:Pleural Neoplasms / Q000145:classification / Q000473:pathology*; D011379:Prognosis; D054363:Solitary Fibrous Tumor, Pleural / Q000473:pathology