Magnetic resonance angiography of collateral blood supply to spinal cord in thoracic and thoracoabdominal aortic aneurysm patients.
OBJECTIVE
Preservation of spinal cord blood supply during descending thoracic (TAA) and thoracoabdominal aortic aneurysm (TAAA) surgery is mandatory to prevent neurologic complications. Although collateral arteries have been identified occasionally and are considered crucial for maintaining spinal cord function in the individual patient, their critical functionality is poorly understood and very little experience exists with visualization. This study investigated whether the preoperative and postoperative presence or absence of collateral arteries detected by magnetic resonance angiography (MRA) is related to spinal cord function during the intraoperative exclusion of the segmental supply to the Adamkiewicz artery.


METHODS
Spinal cord MRA was used to localize the Adamkiewicz artery and its segmental supplier in 85 patients scheduled for open elective surgery for TAA or TAAA. The segmental artery to the Adamkiewicz artery was inside the cross-clamped aortic area in 55 patients, and spinal cord supply was consequently dependent on collateral supply. In these 55 patients the presence of collaterals originating from arteries outside the cross-clamped aortic segment was related to changes in the intraoperative motor-evoked potentials (MEPs) that occurred before corrective measures. Twenty-one patients returned for postoperative MRA.


RESULTS
A highly significant (P < .0015) relation was found between the presence of collaterals and intraoperative spinal cord function. In 30 of 31 patients (97%) in whom collaterals were identified, MEPs remained stable. The collaterals in most patients originated caudally to the distal clamp (eg, from the pelvic arteries), which were perfused by means of extracorporeal circulation during cross-clamping. The MEPs declined in 9 of 24 patients (38%) in whom no collaterals were preoperatively visualized. Postoperatively, the 21 patients who had MRA, including 10 in whom preoperatively no collaterals were found, displayed a well-developed collateral network.


CONCLUSIONS
Collateral arteries supplying the spinal cord can be systematically visualized using MRA. Spinal cord blood supply during open aortic surgery may crucially depend on collateral arteries. Preoperatively identified collateral supply was 97% predictive for stable intraoperative spinal cord function. Patients in whom no collaterals can be depicted preoperatively are at increased risk for spinal cord dysfunction.
Backes
Walter H
WH
Department of Radiology, Maastricht University Hospital, Maastricht, The Netherlands.
Nijenhuis
Robbert J
RJ
Mess
Werner H
WH
Wilmink
Freke A
FA
Schurink
Geert Willem H
GW
Jacobs
Michael J
MJ
D000328:Adult; D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis* / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis* / Q000601:surgery*; D003097:Collateral Circulation; D003287:Contrast Media / Q000494:pharmacology; D017558:Elective Surgical Procedures / Q000379:methods; D019054:Evoked Potentials, Motor; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods; D011336:Probability; D011446:Prospective Studies; D011856:Radiographic Image Enhancement; D018570:Risk Assessment; D013116:Spinal Cord / Q000098:blood supply*; D016896:Treatment Outcome
D003287:Contrast Media