Fertility preservation in patients with non-oncological conditions.
In addition to cancers, many non-oncological conditions, including chromosomal abnormalities and autoimmune disorders, are currently treated with gonadotoxic agents that can lead to premature ovarian failure. Because of the young age of some of the women affected by these conditions, attempts to preserve fertility and ovarian function are recommended. To date, retrieval of immature oocytes followed by in-vitro maturation and vitrification has been found to be especially useful for women who cannot undergo ovarian stimulation, or when there is a contraindication.
Gidoni
Yariv
Y
Department of Obstetrics and Gynecology, McGill University, 687 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.
Holzer
Hananel
H
Tulandi
Togas
T
Tan
Seang Lin
SL
D000367:Age Factors; D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy; D015925:Cryopreservation; D003603:Cytotoxins / Q000009:adverse effects*; D005260:Female; D005298:Fertility; D006402:Hematologic Diseases / Q000188:drug therapy; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D008594:Menopause, Premature; D009865:Oocytes; D010052:Ovariectomy / Q000009:adverse effects
D003603:Cytotoxins