Trifluoromethylation of N-benzoylhydrazones.
A method for the nucleophilic trifluoromethylation of N-benzoylhydrazones using Me3SiCF3/AcONa has been described. The CN bond of the hydrazones is activated by difluoroboron group, which is introduced by means of boron trifluoride and allylsilane.
Dilman
Alexander D
AD
N.D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Russian Federation. adil25@mail.ru
Arkhipov
Dmitry E
DE
Levin
Vitalij V
VV
Belyakov
Pavel A
PA
Korlyukov
Alexander A
AA
Struchkova
Marina I
MI
Tartakovsky
Vladimir A
VA
D001554:Benzene / Q000737:chemistry*; D018360:Crystallography, X-Ray; D017611:Fluorine Compounds / Q000737:chemistry*; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry; D008745:Methylation; D008958:Models, Molecular; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry
D017611:Fluorine Compounds; D006835:Hydrazones; D012821:Silanes; D001554:Benzene