Association between plasma lipid levels and migraine in subjects aged > or =50 years: preliminary data from the Zabùt Aging Project.
We evaluated the association between lipid levels and migraine using cross-sectional, population-based data of 1809 subjects aged > or =50 years; 151 subjects with migraine and 1658 nonmigraineurs were included. Diagnosis of migraine was carried out using the criteria of the International Headache Society. The following plasma lipids were collected: total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG). Only TC (p<0.003) and LDL-C levels (p<0.004) were significantly higher in migraineurs than nonmigraineurs. After multiple adjustments, only elevated TC (> or =220 mg/dl) was significantly associated with migraine (OR [95% CI]=1.6 [1.1-2.3]); this association increased in elderly males with migraine (OR [95% CI]=3.8 [1.4-9.9]). According to our results, TC plasma levels should be closely monitored in elderly males with migraine.
Monastero
Roberto
R
Adult Headache Center Department of Clinical Neuroscience, University of Palermo, Via La Loggia 1, 90129 Palermo, Italy. roberto.monastero@unipa.it
Pipia
Carmela
C
Cefalù
Angelo B
AB
Liveri
Eva Turco
ET
Rosano
Rosamaria
R
Camarda
Rosolino
R
Camarda
Cecilia
C
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D007558:Italy; D008055:Lipids / Q000097:blood* / Q000145:classification; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood*; D016017:Odds Ratio; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides