Association between plasma lipid levels and migraine in subjects aged > or =50 years: preliminary data from the Zabùt Aging Project.
We evaluated the association between lipid levels and migraine using cross-sectional, population-based data of 1809 subjects aged > or =50 years; 151 subjects with migraine and 1658 nonmigraineurs were included. Diagnosis of migraine was carried out using the criteria of the International Headache Society. The following plasma lipids were collected: total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG). Only TC (p<0.003) and LDL-C levels (p<0.004) were significantly higher in migraineurs than nonmigraineurs. After multiple adjustments, only elevated TC (> or =220 mg/dl) was significantly associated with migraine (OR [95% CI]=1.6 [1.1-2.3]); this association increased in elderly males with migraine (OR [95% CI]=3.8 [1.4-9.9]). According to our results, TC plasma levels should be closely monitored in elderly males with migraine.
Adult Headache Center Department of Clinical Neuroscience, University of Palermo, Via La Loggia 1, 90129 Palermo, Italy. roberto.monastero@unipa.it
Roberto
R
Monastero
Carmela
C
Pipia
Angelo B
AB
Cefalù
Eva Turco
ET
Liveri
Rosamaria
R
Rosano
Rosolino
R
Camarda
Cecilia
C
Camarda
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D007558:Italy; D008055:Lipids / Q000097:blood* / Q000145:classification; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood*; D016017:Odds Ratio; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides