Conformal and intensity-modulated radiotherapy for cervical cancer.
Three-dimensional radiotherapy planning techniques, including conformal radiotherapy and intensity-modulated radiotherapy, have potential for improving outcomes in cervical cancer. Accurate target volume definition is essential in order to maximise normal tissue sparing while minimising the risk of a geographical miss. This reduction in toxicity provides the option of dose escalation, particularly with simultaneous integrated boost intensity-modulated radiotherapy. The evidence for the current use and potential applications of these techniques in the treatment of cervical cancer are discussed.
Department of Radiotherapy, Hammersmith Hospital, Du Cane Road, London, UK. alexandra.taylor@imperial.nhs.uk
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D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D011874:Radiometry / Q000295:instrumentation / Q000379:methods; D020266:Radiotherapy, Conformal / Q000295:instrumentation / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation* / Q000379:methods; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*