You're too old for that.
Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.
Shah
Vinay A
VA
Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1091, USA.
Randhawa
Sandeep
S
Mizen
Thomas
T
Lee
Andrew G
AG
Foroozan
Rod
R
D000367:Age Factors; D000368:Aged; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D029242:Optic Atrophy, Hereditary, Leber / Q000175:diagnosis* / Q000188:drug therapy; D009900:Optic Nerve / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D012607:Scotoma / Q000175:diagnosis*; D058609:Visual Field Tests; D014794:Visual Fields
D007166:Immunosuppressive Agents; D011241:Prednisone; D008727:Methotrexate