Dural infiltration of metastatic Hodgkin's lymphoma.
Hodgkin's disease is a neoplasm of clonal Reed-Sternberg cells. Intracranial Hodgkin's lymphoma is rare. We present a unique case of a 57-year-old woman with secondary intracranial lymphoma infiltrating the dura. Her past medical history included Hodgkin's lymphoma from which she was deemed to be in remission at the time of presentation. Following an acute onset of seizures, she underwent radiological investigations that demonstrated an enhancing right-sided temporal dural-based space occupying lesion. Histopathological findings revealed nodular sclerosing Hodgkin's lymphoma with pathognomonic Reed-Sternberg cells. In cases of intracranial lesions with dural infiltration, Hodgkin's lymphoma should be considered in the diagnosis.
Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
V A
VA
Elwell
L
L
Carney
P
P
Johns
J P
JP
Grieve
D004388:Dura Mater / Q000473:pathology*; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008224:Lymphoma, Follicular / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000556:secondary*; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D016539:Reed-Sternberg Cells / Q000473:pathology*; D012640:Seizures / Q000209:etiology