Control of mosquito vectors of tropical infectious diseases: (1) bioefficacy of mosquito coils containing several pyrethroids and a synergist.
The bioefficacy of mosquito coils containing several pyrethroids were tested in a 25 m3 room against Culex pipiens quinquefasciatus, Aedes aegypti and Anopheles dirus. The test results were compared with tests against Culex pipiens pallens in Japan. Based on the KT50 values (the 50% knockdown time) of mosquito coils containing dl, d-T80-allethrin, d, d-T-prallethrin and methoxymethyl-tetrafluorobenzyl tetramethyl-cyclopropanecarboxylate (K-3050) at doses of 0.05-0.5% (w/w) with or without a synergist, the pyrethroid susceptibility of the four mosquito species was as follows: Cx. p. quinquefasciatus was several times more tolerant to pyrethroids than Cx. p. pallens, Ae. aegypti was a further several times more tolerant than Cx. p. quinquefasciatus, and An. dirus was more susceptible than Cx. p. pallens (KT50 value: about half of Cx. p. pallens). The order of their susceptibilities is common for pyrethroids. Mosquito coils containing d, d-T-prallethrin and K-3050 at doses of 0.05-0.2% (w/w) and N-(2-ethylhexyl)bicycle-[2,2,1]-hept-5-ene-2,3-dicarboxyimide as a synergist at a ratio of 2 times the active ingredient were highly effective against Ae. aegypti, the most important mosquito vector for dengue fever.
Katsuda
Yoshio
Y
Research and Development Laboratory, Dainihon Jochugiku Co, Ltd, Osaka, Japan. y.minamite@kincho.co.jp
Leemingsawat
Somjai
S
Thongrungkiat
Supatra
S
Komalamisara
Narumon
N
Kanzaki
Tsutomu
T
Watanabe
Tomoe
T
Kahara
Tomoko
T
D000818:Animals; D003141:Communicable Diseases / Q000469:parasitology*; D009033:Culicidae / Q000187:drug effects*; D006801:Humans; D007564:Japan; D009032:Mosquito Control / Q000379:methods*; D011722:Pyrethrins / Q000494:pharmacology*; D013785:Thailand; D014329:Tropical Climate
D011722:Pyrethrins