Conformal and intensity-modulated radiotherapy for cervical cancer.
Three-dimensional radiotherapy planning techniques, including conformal radiotherapy and intensity-modulated radiotherapy, have potential for improving outcomes in cervical cancer. Accurate target volume definition is essential in order to maximise normal tissue sparing while minimising the risk of a geographical miss. This reduction in toxicity provides the option of dose escalation, particularly with simultaneous integrated boost intensity-modulated radiotherapy. The evidence for the current use and potential applications of these techniques in the treatment of cervical cancer are discussed.
Taylor
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Department of Radiotherapy, Hammersmith Hospital, Du Cane Road, London, UK. alexandra.taylor@imperial.nhs.uk
Powell
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D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D011874:Radiometry / Q000295:instrumentation / Q000379:methods; D020266:Radiotherapy, Conformal / Q000295:instrumentation / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation* / Q000379:methods; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*