Trifluoromethylation of N-benzoylhydrazones.
A method for the nucleophilic trifluoromethylation of N-benzoylhydrazones using Me3SiCF3/AcONa has been described. The CN bond of the hydrazones is activated by difluoroboron group, which is introduced by means of boron trifluoride and allylsilane.
N.D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Russian Federation. adil25@mail.ru
Alexander D
AD
Dilman
Dmitry E
DE
Arkhipov
Vitalij V
VV
Levin
Pavel A
PA
Belyakov
Alexander A
AA
Korlyukov
Marina I
MI
Struchkova
Vladimir A
VA
Tartakovsky
D001554:Benzene / Q000737:chemistry*; D018360:Crystallography, X-Ray; D017611:Fluorine Compounds / Q000737:chemistry*; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry; D008745:Methylation; D008958:Models, Molecular; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry
D017611:Fluorine Compounds; D006835:Hydrazones; D012821:Silanes; D001554:Benzene