Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli.
A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3'-formyl-5'-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-alpha-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.
Faculte des Sciences de Monastir, Laboratoire de Chimie des Substances Naturelles et de Synthese Organique 99/UR/12-26, 5000 Monastir, Tunisie.
Samia
S
Ammar
Mohamed Ali
MA
Mahjoub
Houda Ben
HB
Abdelkader
Kaouther
K
Liouane
Ines
I
Skandarani
Leila
L
Chekir-Ghedira
Zine
Z
Mighri
D031823:Anagallis / Q000737:chemistry*; D016587:Antimutagenic Agents / Q000302:isolation & purification*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D052160:Benzothiazoles / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006834:Hydrazines / Q000737:chemistry; D015394:Molecular Structure; D009153:Mutagens / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010851:Picrates; D013451:Sulfonic Acids / Q000737:chemistry
D016587:Antimutagenic Agents; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D005419:Flavonoids; D006834:Hydrazines; D009153:Mutagens; D010851:Picrates; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl