[Ma2 antibody and multiple mononeuropathies].
Anti-Ma2 antibodies belong to a family of onconeuronal antibodies that target proteins expressed in brain, testis and several tumors. Previously observed in patients presenting with limbic encephalitis, they seem to be associated with several other paraneoplastic syndromes. We report the case of a 73-year-old woman presenting sensory and motor neuropathy associated with non-small-cell lung cancer who had Ma2-antibodies.
Ayrignac
X
X
Service de neurologie, CHU de Nîmes, 30029 Nîmes cedex, France.
Castelnovo
G
G
Landrault
E
E
Fayolle
H
H
Pers
Y-M
YM
Honnorat
J
J
Campello
C
C
Figarella-Branger
D
D
Labauge
P
P
D000368:Aged; D000912:Antibodies, Neoplasm / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000276:immunology*; D015415:Biomarkers / Q000032:analysis*; D002289:Carcinoma, Non-Small-Cell Lung / Q000145:classification* / Q000000981:diagnostic imaging / Q000276:immunology*; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000000981:diagnostic imaging / Q000209:etiology* / Q000276:immunology*; D006801:Humans; D008175:Lung Neoplasms / Q000145:classification* / Q000000981:diagnostic imaging / Q000276:immunology*; D008279:Magnetic Resonance Imaging; D009419:Nerve Tissue Proteins / Q000276:immunology*; D013902:Radiography, Thoracic
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D015415:Biomarkers; C119249:Ma2 antigen; D009419:Nerve Tissue Proteins