Relationship between presurgical memory performance on the Wechsler Memory Scale-III and memory change following temporal resection for treatment of intractable epilepsy.
Previous research demonstrated a relationship between preoperative memory measured by the Wechsler Memory Scale-Revised (WMS-R) and postsurgical memory change in patients who underwent left (LATL), but not right (RATL) anterior temporal lobectomy. The current study replicated previous efforts using the Wechsler Memory Scale-Third Edition (WMS-III) in a larger sample. The WMS-III was administered to 161 patients with medically intractable epilepsy prior to and approximately 6 months following LATL or RATL. Correlations between presurgical memory on WMS-III indices and memory change following surgery were calculated for each group. Significant negative relationships were found between pre- and postsurgical memory scores in patients who underwent LATL on all WMS-III measures (r=-0.31 to -0.43). Significant negative correlations were observed in patients who underwent RATL only on visual memory measures (r=-0.24 to -0.44). Findings support previous conclusions using the WMS-R showing that patients who undergo LATL with higher presurgical memory ability are at greater risk for memory decline following temporal resection than patients with lower presurgical memory scores.
Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Daniel J
DJ
Harvey
Richard I
RI
Naugle
Joshua
J
Magleby
Jessica S
JS
Chapin
Imad M
IM
Najm
William
W
Bingaman
Robyn M
RM
Busch
D000293:Adolescent; D000328:Adult; D038481:Anterior Temporal Lobectomy; D004292:Dominance, Cerebral / Q000502:physiology; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis*; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis*; D011379:Prognosis; D011594:Psychometrics; D012189:Retrospective Studies; D012307:Risk Factors; D014888:Wechsler Scales / Q000706:statistics & numerical data*