Radical prostatectomy in the 21st century - the gold standard for localized and locally advanced prostate cancer.
Radical prostatectomy for treatment of prostate cancer is a technically sophisticated operation. Simpler therapies have therefore been developed in the course of decades. The decisive advantage of a radical operation is the chance of a cure with minimal collateral damage. It is the only approach that enables precise tumor staging. The 10-year progression-free survival probability is approximately 85% for a localized tumor with negative resection margins. This high cure rate is unsurpassed by competitive treatment modalities. Nowadays, experienced surgeons achieve excellent functional results (for example, recovery of continence and erectile function) with minimum morbidity. Even in the locally advanced stage, results are very good compared to those obtained with other treatment modalities. Pathological staging enables stratified adjuvant therapy based on concrete information. The overall prognosis can thus be significantly improved.
Department of Urology, Charité Universitätsmedizin Berlin, Berlin , Germany.
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Schostak
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Miller
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Schrader
D006801:Humans; D008297:Male; D011468:Prostatectomy / Q000009:adverse effects / Q000706:statistics & numerical data; D011471:Prostatic Neoplasms / Q000601:surgery*