[Lung protective ventilation - supportive and adjunctive therapies in acute lung injury].
Various supportive and adjunctive therapies to conventional mechanical ventilation have been evaluated in patients with acute lung injury and acute respiratory distress syndrome (e.g. nitric oxide, prone position, surfactant, glucocorticoids). Although some investigations have shown promising improvements in oxygenation and physiological variables, large randomized trials of adjunctive and supportive therapies showed no impact on survival.
David
Matthias
M
Klinik für Anästhesiologieder Johannes Gutenberg-Universität in Mainz. david@uni-mainz.de
Markstaller
Klaus
K
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D005858:Germany; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012121:Respiration, Artificial / Q000009:adverse effects*; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000517:prevention & control*
D000893:Anti-Inflammatory Agents