Admission hyperglycemia and length of hospital stay in patients with diabetes and heart failure: a prospective cohort study.
The authors assessed the relationship between glycemia and length of hospital stay (LOS) in a prospective cohort study of patients with diabetes mellitus and heart failure (HF). Of 212 patients with acute HF exacerbation, 119 (56%) also had diabetes. The mean age of the cohort was 63+/-0.87 years, and the mean body mass index was 29.3 kg/m2. Diabetic patients had significantly longer LOS compared with the nondiabetics (5.0+/-0.29 vs 3.4+/-0.19; P<.001). In patients with diabetes, the mean glycated hemoglobin A1c was 8.3%, admission blood glucose (BG) was 169+/-7.7 mg/dL, and average BG was 196+/-8.1 mg/dL. After adjusting for age, sex, weight, hypertension, renal function, and anemia, LOS was significantly correlated with admission BG (r=0.31; P<.001) and average BG (r=0.34; P=.001). In patients with acute HF exacerbation, diabetes significantly prolonged LOS. Hyperglycemia correlated with LOS.
Department of Medicine, SUNY Downstate and King County Hospital Center, Brooklyn, NY, USA.
Yohannes
Y
Gebreegziabher
Peter A
PA
McCullough
Chard
C
Bubb
Lesel
L
Loney-Hutchinson
John N
JN
Makaryus
Naveen
N
Anand
Vijay
V
Divakaran
Philippe
P
Akhrass
Anis
A
Alam
Hans von
Hv
Gizycki
Samy I
SI
McFarlane
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D048909:Diabetes Complications / Q000097:blood*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006333:Heart Failure / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000150:complications*; D007902:Length of Stay / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D011446:Prospective Studies; D012307:Risk Factors; D013318:Stroke Volume; D013997:Time Factors
D001786:Blood Glucose; D006442:Glycated Hemoglobin