Arsenic in rice: II. Arsenic speciation in USA grain and implications for human health.
Rice is a potentially important route of human exposure to arsenic, especially in populations with rice-based diets. However, arsenic toxicity varies greatly with species. The initial purpose of the present study was to evaluate arsenic speciation in U.S. rice. Twenty-four samples containing high levels of arsenic and produced in different regions of the U.S were selected from a previous market-basket survey. Arsenite and dimethyl arsinic acid (DMA) were the major species detected. DMA increased linearly with increasing total As but arsenite remained fairly constant at approximately 0.1 mg kg(-1), showing that rice high in As was dominated by DMA. A similar result was obtained when our data was combined with other published speciation studies for U.S. rice. However, when all published speciation data for rice was analyzed a second population dominated by inorganic As and lower levels of DMA was found. We thus categorized rice into DMA and Inorganic As types. Rice from the U.S. was predominantly the DMA type, as were single samples from Australia and China, whereas rice from Asia and Europe was the Inorganic As type. We suggest that methylation of As occurs within rice and that genetic differences lead to the two rice types. Insufficient understanding of DMA toxicity precludes a firm assessment of the relative health risks associated with the two rice types but, based on current knowledge, we suggest that the DMA rice type is likely to be less of a health risk than the Inorganic As rice type and, on this basis, rice from the U.S. may be safer than rice from Asia and Europe.
Department of Crop and Soil Sciences, Cornell University, Ithaca, New York 14853, USA. yjz1@cornell.edu
Yamily J
YJ
Zavala
Russell
R
Gerads
Hakan
H
Gorleyok
John M
JM
Duxbury
D001151:Arsenic / Q000032:analysis*; D004781:Environmental Exposure; D006801:Humans; D012275:Oryza / Q000737:chemistry*; D011786:Quality Control; D014481:United States
D001151:Arsenic