Pediatric optic neuritis.
OBJECTIVE
Describe the clinical characteristics of pediatric optic neuritis.


METHODS
Retrospective observational case series was performed on patients < or = 12 years of age with optic neuritis at Childrens Hospital Los Angeles.


RESULTS
Thirty-one patients (48 eyes) were identified. Mean follow-up was 2.7 years. There were 17 preadolescents (< 10-years-old) in group I, and 14 adolescents (10--12-years-old) in group II. Females comprised 59% of group I, and 71% of group II. Bilateral cases comprised 65% from group I, and 43% from group II. Five patients from group I had acute disseminated encephalomyelitis (ADEM). Two patients from group II had multiple sclerosis (MS). No other patients developed MS. There was no difference in initial or final vision for the eyes with or without steroid treatment.


CONCLUSIONS
Pediatric optic neuritis has no gender or racial predilection, is usually bilateral, and is associated with ADEM rather than MS.
Chirapapaisan
Niphon
N
Department of Ophthalmology, Siriraj Hospital, 2 Prannok, Bangkoknoi, Bangkok 10700, Thailand. sincs@mahidol.ac.th
Borchert
Mark S
MS
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D004673:Encephalomyelitis, Acute Disseminated / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000209:etiology; D009902:Optic Neuritis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012189:Retrospective Studies