Carcinosarcoma of the orbit: report of two cases and review of the literature.
OBJECTIVE
To report the clinicopathologic features of 2 patients with carcinosarcoma of the orbit.


METHODS
Case reports.


METHODS
Two patients with orbital carcinosarcoma were identified.


METHODS
Retrospective chart review with clinicopathologic correlation and literature review.


METHODS
Clinical examination, imaging studies, and histopathologic findings.


RESULTS
Two patients, a 56-year-old woman and a 91-year-old woman, with orbital carcinosarcoma were identified. Both tumors contained sarcomatous and carcinomatous components and invaded periorbital structures.


CONCLUSIONS
Carcinosarcoma may arise in the orbit or extend into the orbit from the paranasal sinuses. This malignant neoplasm should be aggressively treated with a combination of surgical resection, chemotherapy, and radiation therapy.
Prakalapakorn
Sasapin G
SG
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Bernardino
C Robert
CR
Auclair
Paul L
PL
Grossniklaus
Hans E
HE
D000369:Aged, 80 and over; D002296:Carcinosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed