Frequency of celiac disease is not increased among multiple sclerosis patients.
We evaluated the presence of IgA and IgG celiac disease-related antibodies in a sample of 217 patients with multiple sclerosis (MS) and in a sample of 200 controls not affected by neurological disorders. None of the 217 patients with MS presented IgG and IgA anti-gliadin, anti-endomysial antibodies, anti-tissue transglutaminase and anti-reticulin, whereas only one of the selected controls presented specific antibodies; this subject resulted to be effectively affected by celiac disease. Our data did not show an increased frequency of celiac disease among patients with MS.
Dipartimento di Neuroscienze, Università di Catania, Via Santa Sofia no. 78, Catania, Italy.
A
A
Nicoletti
F
F
Patti
S
S
Lo Fermo
A
A
Sciacca
P
P
Laisa
A
A
Liberto
S
S
Lanzafame
D
D
Contraffatto
C
C
D'Agate
A
A
Russo
M
M
Zappia
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D044182:Benzylisoquinolines / Q000276:immunology; D002446:Celiac Disease / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D005903:Gliadin / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000276:immunology; D016036:Seroepidemiologic Studies; D011503:Transglutaminases / Q000276:immunology
D001323:Autoantibodies; D044182:Benzylisoquinolines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D005903:Gliadin; D011503:Transglutaminases; C003298:reticuline