Choriocarcinoma in an AIDS patient--relapsing but not fatal.
Choriocarcinoma is associated with high mortality in immunocompromised patients, in contrast to a good prognosis in immunocompetent individuals. Respiratory failure due to metatstatic choriocarcinoma is associated with high mortality in any patient. We report a case of a woman with AIDS that survived metastatic choriocarcinoma and respiratory failure. We also observed that in contrast to some in vitro studies, the markedly elevated levels of beta-subunit of human chorionic gonadotropin in this patient did not have any apparent inhibitory effect on viral replication.
Shah
Archan M
AM
Department of Medicine, Baystate Medical Center, Tufts University School of Medicine, 759 Chestnut Street - S2570, Springfield, MA 01199, USA. shaharch@yahoo.com
Tidswell
Mark
M
Prefontaine
Michel
M
Skiest
Daniel J
DJ
Pantanowitz
Liron
L
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology / Q000517:prevention & control; D000328:Adult; D002822:Choriocarcinoma / Q000209:etiology / Q000517:prevention & control; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005260:Female; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1 / Q000502:physiology; D006801:Humans; D012008:Recurrence; D012131:Respiratory Insufficiency; D014594:Uterine Neoplasms / Q000209:etiology / Q000517:prevention & control; D019562:Viral Load
D018997:Chorionic Gonadotropin, beta Subunit, Human