Asymmetric EM reveals new twists in phage phi29 biology.
Tang et al. (2008) probe the virion structure of bacteriophage phi29 by asymmetric reconstructions of cryo-electron microscopy images, visualizing subunit conformations, protein-DNA interactions, and a novel twist of dsDNA that may aid in retention of the genome prior to ejection.
Robert L
RL
Duda
James F
JF
Conway
D017103:Bacillus Phages / Q000235:genetics / Q000648:ultrastructure*; D020285:Cryoelectron Microscopy; D004279:DNA, Viral / Q000737:chemistry; D007091:Image Processing, Computer-Assisted; D014771:Virion / Q000737:chemistry* / Q000648:ultrastructure*
D004279:DNA, Viral