Antifungal activity of the lemongrass oil and citral against Candida spp.
Superficial mycoses of the skin are among the most common dermatological infections, and causative organisms include dermatophytic, yeasts, and non-dermatophytic filamentous fungi. The treatment is limited, for many reasons, and new drugs are necessary. Numerous essential oils have been tested for both in vitro and in vivo antifungal activity and some pose much potential as antifungal agents. By using disk diffusion assay, we evaluated the antifungal activity of lemongrass oil and citral against yeasts of Candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis). This study showed that lemongrass oil and citral have a potent in vitro activity against Candida spp.
Silva
Cristiane de Bona da
Cde B
Pos-Graduation program in Pharmaceuthical Sciences, Pharmaceutical School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. csbona@smail.ufsm.br
Guterres
Sílvia S
SS
Weisheimer
Vanessa
V
Schapoval
Elfrides E S
EE
D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D052978:Disk Diffusion Antimicrobial Tests; D039821:Monoterpenes / Q000494:pharmacology*; D010938:Plant Oils / Q000494:pharmacology*; D013729:Terpenes / Q000494:pharmacology*
D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents; D039821:Monoterpenes; D010938:Plant Oils; D013729:Terpenes; C052901:lemongrass oil; C007076:citral