Detection of microscopic leaks in fermenter cooling coils.
Microscopic leaks in fermenter cooling coils were identified as the source of chronic fermentation contaminations. Methods used to identify the problem in production fermenters are described. Recommendations for upgrading quality control criteria for new installations are presented.
Fermentation Products Department, Hoffmann-La Roche, Belvidere, New Jersey 07823.
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CA
Perkowski
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Daransky
J
J
Williams