Aggressive thyroid carcinoma showing thymic-like differentiation (CASTLE): case report and review of the literature.
Carcinoma showing thymic-like differentiation (CASTLE) is a rare tumour of the thyroid, which arises from ectopic thymic tissue or remnants of branchial pouches. A systematic review of English literature evidences less than thirty cases; from them, it clearly appears that CASTLE is considered an indolent slow-growing neoplasia even when lymph nodes metastasis are present. We describe a case of very aggressive CASTLE, which showed seeding along fine needle aspiration tract.
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia, Italy.
Carlo
C
Cappelli
Andrea
A
Tironi
Gian Pietro
GP
Marchetti
Ilenia
I
Pirola
Elvira
E
De Martino
Andrea
A
Delbarba
Maurizio
M
Castellano
Enrico Agabiti
EA
Rosei
D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D002454:Cell Differentiation; D002828:Choristoma / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D013950:Thymus Gland; D013964:Thyroid Neoplasms / Q000473:pathology*