Progressive apraxia of speech presenting as isolated disorder of speech articulation and prosody: a case report.
Apraxia of speech (AOS) is a rare disorder of motor speech programming, and few case reports have included sufficient description of both clinical findings and lesion localization. We report a case with an isolated progressive speech articulation deficit and brain involvement restricted to the left superior frontal gyrus. This case suggests that slowly progressive AOS may be a clinical disorder distinct from primary progressive aphasia, and that it can occur without language disorders or bucco-facial apraxia. Our findings highlight the importance of the left hemisphere in speech articulatory deficits and suggest that the left superior frontal gyrus plays a crucial role in specific articulatory processes.
Unit of Neurology, Regina Apostolorum Hospital, Rome, Italy. monica.ricci@libero.it
M
M
Ricci
M
M
Magarelli
V
V
Todino
A
A
Bianchini
E
E
Calandriello
R
R
Tramutoli
D000368:Aged; D001072:Apraxias / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D001184:Articulation Disorders / Q000209:etiology*; D018450:Disease Progression; D005260:Female; D005625:Frontal Lobe / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D049268:Positron-Emission Tomography; D015899:Tomography, Emission-Computed, Single-Photon; D014956:Writing