Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli.
A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3'-formyl-5'-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-alpha-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.
Ammar
Samia
S
Faculte des Sciences de Monastir, Laboratoire de Chimie des Substances Naturelles et de Synthese Organique 99/UR/12-26, 5000 Monastir, Tunisie.
Mahjoub
Mohamed Ali
MA
Abdelkader
Houda Ben
HB
Liouane
Kaouther
K
Skandarani
Ines
I
Chekir-Ghedira
Leila
L
Mighri
Zine
Z
D031823:Anagallis / Q000737:chemistry*; D016587:Antimutagenic Agents / Q000302:isolation & purification*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D052160:Benzothiazoles / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006834:Hydrazines / Q000737:chemistry; D015394:Molecular Structure; D009153:Mutagens / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010851:Picrates; D013451:Sulfonic Acids / Q000737:chemistry
D016587:Antimutagenic Agents; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D005419:Flavonoids; D006834:Hydrazines; D009153:Mutagens; D010851:Picrates; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl