[On the glycinergic component of the mechanisms of medial vestibular nucleus neurons functioning].
Tests with surviving medulla sections of white non-strain male rats showed 100 microM of strychnine (glycine antagonist) but not 20-100 microM GABA-negative biku-kullin and picrotoxin reduced almost double the postsynaptic N1-amplitude of the population response to afferent vestibular stimulation in the ventral region of the medial vestibular nucleus (MVN). This suggests a glycinergic component in the mechanisms of MVN neurons functioning and absence of a GAMA-ergic analog in healthy adult rats.
Motin
V G
VG
Iasnetsov
V V
VV
D000818:Animals; D004558:Electric Stimulation; D019706:Excitatory Postsynaptic Potentials / Q000187:drug effects; D018684:Glycine Agents / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009474:Neurons / Q000187:drug effects* / Q000502:physiology*; D051381:Rats; D013331:Strychnine / Q000008:administration & dosage / Q000494:pharmacology*; D014726:Vestibular Nuclei / Q000187:drug effects* / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000096:biosynthesis
D018684:Glycine Agents; D005680:gamma-Aminobutyric Acid; D013331:Strychnine