Heterogeneity of drug target expression among metastatic lesions: lessons from a breast cancer autopsy program.
Steeg
Patricia S
PS
Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA. steegp@mail.nih.gov
D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001344:Autopsy; D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D016503:Drug Delivery Systems; D005260:Female; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D018740:Genetic Heterogeneity / Q000187:drug effects*; D006801:Humans; D008954:Models, Biological; D009362:Neoplasm Metastasis
D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor