Coricidin HBP abuse: patient characteristics and psychiatric manifestations as recorded in an inpatient psychiatric unit.
Coricidin HBP, a cold medication containing dextromethorphan, has become a popular agent abused among adolescents. This retrospective chart review examines the potential psychiatric manifestations of Coricidin HBP misuse and patterns of use among patients treated in an inpatient child and adolescent psychiatric unit. Coricidin HBP use was documented in 47 patient. The data revealed that Coricidin HBP use was associated with: (a) predominantly depressive symptomatology; (b) transient substance-induced psychosis; (c) cardiac toxicity; and (d) greater quantities used per episode by Caucasians. Clinicians treating adolescents need to be aware of the abuse potential and psychiatric manifestations of this dextromethorphan-containing product.
Loma Linda University Medical Center 11374 Mountain View Avenue, Loma Linda, CA 92354, USA.
Daniel L
DL
Dickerson
Mary Ann
MA
Schaepper
Mark D
MD
Peterson
Michelle D
MD
Ashworth
D000082:Acetaminophen / Q000506:poisoning*; D000293:Adolescent; D000367:Age Factors; D000437:Alcoholism / Q000453:epidemiology; D002140:California; D002648:Child; D002744:Chlorpheniramine / Q000506:poisoning*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000139:chemically induced* / Q000453:epidemiology*; D003915:Dextromethorphan / Q000506:poisoning*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D062787:Drug Overdose / Q000453:epidemiology*; D005260:Female; D006327:Heart Block / Q000139:chemically induced* / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D010665:Phenylpropanolamine / Q000506:poisoning*; D011567:Psychiatric Department, Hospital / Q000706:statistics & numerical data; D011605:Psychoses, Substance-Induced / Q000453:epidemiology*; D012189:Retrospective Studies; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000453:epidemiology*; D013406:Suicide, Attempted / Q000523:psychology / Q000706:statistics & numerical data; D017180:Tachycardia, Ventricular / Q000139:chemically induced* / Q000453:epidemiology
D004338:Drug Combinations; C479098:acetaminophen, chlorpheniramine, dextromethorphan, phenylpropanolamine drug combination; D010665:Phenylpropanolamine; D000082:Acetaminophen; D002744:Chlorpheniramine; D003915:Dextromethorphan