A simple and selective sensor for the determination of ascorbic acid in vitamin C tablets based on paptode.
A method for the determination of ascorbic acid in vitamin C tablets based on a very simple paptode design on TLC strips is described. This procedure is based on the reduction of iron(III) with ascorbic acid and the formation of a colorful red complex with immobilized 2,2'-dipyridyl (dipy) on TLC strips. The linear range of the system was 20-200 ppm with a detection limit of 1 ppm and a relative standard deviation of 1.5% (n = 28). The parameters, such as pH, concentration of iron(III), concentration of dipy and the volume of dipy per 1 cm(2) of TLC strips, were optimized. The proposed sensor was successfully applied for the determination of ascorbic acid in vitamin C tablets.
Chemistry Department, Shiraz University, Shiraz, Iran. abbaspour@chem.susc.ac.ir
Abdolkarim
A
Abbaspour
Abdolreza
A
Khajehzadeh
Abolhassan
A
Noori
D015082:2,2'-Dipyridyl / Q000737:chemistry; D001205:Ascorbic Acid / Q000032:analysis* / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D002855:Chromatography, Thin Layer / Q000379:methods*; D003116:Color; D006863:Hydrogen-Ion Concentration; D007501:Iron / Q000737:chemistry; D010084:Oxidation-Reduction; D012680:Sensitivity and Specificity; D012984:Software; D013607:Tablets / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D013607:Tablets; D015082:2,2'-Dipyridyl; D007501:Iron; D001205:Ascorbic Acid