Life threatening sepsis and mortality following stapled hemorrhoidopexy.
BACKGROUND
Stapled hemorrhoidopexy (SH) was conceived and developed in Europe. Over the past decade, there have been reports of severe, life-threatening complications and 2 deaths. These are the first such cases from the Americas including the third known mortality.


METHODS
Two case reports from US surgeons are combined with eleven reports from the medical literature (both English and non-English speaking journals) for review. Only complications which required emergency abdominal operative intervention with fecal diversion were included.


RESULTS
These 2 cases occurred early in the surgeons' experience with SH (under 10 cases). Incomplete rings (doughnuts) of excised rectal tissue were noted in both patients. There have been a total of 13 patients reported from seven countries across three continents requiring emergency abdominal exploration and fecal diversion for complications related directly to SH. The complications noted in these 13 patients include: 9 cases of perforation, 6 cases of sepsis, 2 cases each of obstruction and Fournier's gangrene, and 1 case each of rectovaginal fistula and intra-abdominal hemorrhage. Seventy per cent of patients underwent abdominal exploration within 3 days of SH, 90% within 5 days. The age range was 24 to 77 years. Two of the 3 oldest patients did not survive the complication (68 and 77 years of age). Three patients succumbed to sepsis in the immediate postoperative period: one on postoperative day 4 after SH (Germany),one on postoperative day 6 after SH (Spain) and the third on postoperative day 10 after SH (US). The 2 mortalities from Europe occurred immediately after colostomy 4 days after SH (Germany) and immediately after re-exploration 6 days after SH and 5 days after initial colostomy (Spain). There have been a few reports of successful, non-operative management in select patients. Symptoms of abdominal pain, urinary retention, and fever after SH frequently herald these severe life-threatening complications.


CONCLUSIONS
SH has resulted in potential serious morbidity and even mortality in the immediate postoperative period. As the procedure has spread in popularity around the world, so too, it appears, have these severe, life-threatening complications. These complications are often heralded by abdominal pain, urinary retention, and fever. Surgeons should be aware of all of the potential complications (and associated warning signs and symptoms) of SH.
Department of Surgery, University of Missouri-Kansas City, Missouri, USA.
William C
WC
Cirocco
D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006484:Hemorrhoids / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D012007:Rectum / Q000382:microbiology / Q000601:surgery; D018805:Sepsis / Q000209:etiology*; D017792:Surgical Stapling; D013537:Sutures / Q000382:microbiology