[Contribution of dynamic interpretation of CA 125 measurements to the understanding of an atypical clinical case].
The dynamic interpretation of the serum concentrations of markers is frequently used to calculate biological indicators of therapeutic efficiency and relapse. But analysis of marker kinetics can also help improve our understanding of the natural history of different types of cancer and their evolution under treatment. This application is illustrated by an analysis of CA 125 kinetics measured in a patient with stage III ovarian cancer treated with multiple lines of chemotherapy and who had a survival time of 9 years.
Département de biologie et de pathologie des tumeurs, Centre Georges-François-Leclerc, Dijon, France. jriedinger@dijon.fnclcc.fr
J-M
JM
Riedinger
M
M
Mousseau
A-S
AS
Gauchez
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D010051:Ovarian Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000473:pathology
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen