Long-term outcome of conventional radiation therapy for central neurocytoma.
The authors report the long-term outcome of conventional radiation therapy (RT) in six cases of central neurocytoma (CN). Between 1985 and 1992, six patients were treated with RT for residual tumors or for prevention of recurrence after surgery. The median follow-up period of radiological and clinical status were 171 (range: 128-229) and 202 months (range: 165-227), respectively. Tumors disappeared in three and reduced in three patients at the last follow-up. One-mortality case due to radiation necrosis and one radiation-induced malignancy occurred. White matter degeneration and cortical atrophy were noticed with slow progression of performance deterioration in two patients. Conventional RT seemed to effectively control residual CN after surgery. However, more sophisticated radiation techniques should be applied to minimize the late sequela.
Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
Sun Ha
SH
Paek
Jung-Ho
JH
Han
Jin Wook
JW
Kim
Chul-Kee
CK
Park
Hee-Won
HW
Jung
Sung-Hye
SH
Park
Il Han
IH
Kim
Dong Gyu
DG
Kim
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D018306:Neurocytoma / Q000473:pathology / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects*; D013995:Time; D014057:Tomography, X-Ray Computed