Bladder cancer and occupational exposures in North Rhine-Westphalia, Germany.
The relationship between exposure to carcinogenic substances and development of bladder cancer was assessed from a case-control study conducted in North Rhine-Westphalia, Germany. The study consisted of 156 cases with bladder cancer and 336 controls with prostate cancer. The primary focus was the role of polycyclic aromatic hydrocarbons (PAHs), since most individuals were considered exposed mainly to substances in this group. Data were collected from male patients who had applied for cancer rehabilitation treatment. Nominally significant smoking-adjusted odds ratio (OR) estimates were obtained for frequent exposures to bitumen (OR = 2.92, 95% CI 1.32-6.48) and tar (OR = 2.09, 95% CI 1.04-4.21) and an ever exposure to paints (OR = 1.69, 95% CI 1.10-2.61). A frequent exposure to pitch showed a non-significant elevated risk (OR = 3.06, 95% CI 0.77-12.10).
Department of Statistics, Technical University of Dortmund, Dortmund, Germany.
Frank
F
Geller
Wolfgang
W
Urfer
Klaus
K
Golka
D000368:Aged; D004785:Environmental Pollutants / Q000009:adverse effects*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016017:Odds Ratio; D011471:Prostatic Neoplasms / Q000453:epidemiology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology*
D004785:Environmental Pollutants