Autogenous osteochondral grafting for treatment of stifle osteochondrosis in dogs.
OBJECTIVE
To develop and assess clinical outcomes for osteochondral autografting for treatment of stifle osteochondrosis (OC) in dogs.


METHODS
Retrospective case series.


METHODS
Dogs with stifle OC (n=10).


METHODS
Osteochondral autografting was developed and optimized in canine cadavers and purpose-bred research dogs using the Osteochondral Autograft Transfer System (OATS). Dogs with stifle OC (n=10 dogs, 12 stifles) were then treated using the OATS system. Outcomes were assessed by radiography (n=12), magnetic resonance imaging (1), second-look arthroscopy (9), lameness scoring (12), and telephone survey of owners (10 clients, 12 stifles) 6-15 months after surgery.


RESULTS
Complications were documented in 4 of the 12 stifles treated and included peri-incisional seromas (3) and marked stifle effusion (1). Subjective assessment of follow-up radiographs revealed evidence of integration of the grafts with maintenance of subchondral bone surface architecture. Subjective assessment of follow-up MRI in 1 stifle revealed evidence for incorporation of grafts with restoration of articular surface contour. Second-look arthroscopy 6-30 weeks after surgery revealed maintenance of articular cartilage at the graft site. Dogs were significantly (P<.001) less lame at follow-up compared with preoperative scores. Based on follow-up owner surveys, only 2 dogs had no pain or lameness; the other dogs were judged to have mild pain and/or lameness. All owners noticed improvement in the dogs' quality of life after surgery.


CONCLUSIONS
Osteochondral autografting deserves consideration and further evaluation as a primary treatment option for stifle OC in dogs.


CONCLUSIONS
Osteochondral autografting for treatment of lateral femoral condylar OC lesions in dogs using OATS instrumentation is safe and results in improved function and quality of life based on owners' perception 6-15 months after treatment.
Cook
James L
JL
Comparative Orthopaedic Laboratory, University of Missouri, 900 E Campus Dr, Columbia, MO 65211, USA. cookjl@missouri.edu
Hudson
Caleb C
CC
Kuroki
Keiichi
K
D000818:Animals; D016025:Bone Transplantation / Q000662:veterinary*; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005260:Female; D005500:Follow-Up Studies; D007794:Lameness, Animal / Q000453:epidemiology / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D010007:Osteochondritis / Q000601:surgery / Q000662:veterinary*; D011183:Postoperative Complications / Q000453:epidemiology / Q000662:veterinary; D011788:Quality of Life; D012189:Retrospective Studies; D013264:Stifle / Q000601:surgery; D016896:Treatment Outcome