Guidelines for the diagnosis of ocular sarcoidosis.
OBJECTIVE
To delineate features of ocular sarcoidosis.


METHODS
Comparison of the old and new Japanese guidelines for diagnosing ocular sarcoidosis by review of the medical records of 100 sarcoidosis patients and 147 patients with non-sarcoidosis uveitis.


RESULTS
The overall diagnostic sensitivity and specificity for the old guidelines were 80.0% and 45.6%; sensitivity and specificity for the new guidelines were 84.0% and 83.0%. Positive and negative predictive values and the likelihood ratios for a positive and negative test result improved. The new guidelines achieved more than 80% specificity for all categories.


CONCLUSIONS
The new guidelines allow easier distinction of ocular sarcoidosis.
Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
Yuri
Y
Asukata
Mami
M
Ishihara
Yukiko
Y
Hasumi
Satoshi
S
Nakamura
Kiyofumi
K
Hayashi
Shigeaki
S
Ohno
Nobuhisa
N
Mizuki
D005128:Eye Diseases / Q000175:diagnosis*; D006801:Humans; D016013:Likelihood Functions; D008499:Medical Records; D009885:Ophthalmology / Q000639:trends; D017410:Practice Guidelines as Topic / Q000592:standards*; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014605:Uveitis / Q000175:diagnosis / Q000209:etiology