Catalysis of Ugi four component coupling reactions by rare earth metal triflates.
Substoichiometric quantities of scandium and ytterbium triflate increase the yield of Ugi four component coupling reactions of aromatic aldehydes 2- to 7-fold. These rare earth metal triflates enhance the reaction yields primarily via activation of the imine intermediate of this multicomponent reaction.
Department of Chemistry, Brown University, 324 Brook Street, Providence, Rhode Island 02912, USA.
Babajide O
BO
Okandeji
Jonathan R
JR
Gordon
Jason K
JK
Sello