Immobilized cell cross-flow reactor.
A cross-current flow reactor was operated using sodium alginate gel entrapped yeast cells under growth conditions. Micron-sized silica, incorporated into the biocatalyst particles (1 mm mean diameter) improved mechanical strength and internal surface adhesion. The process showed decreased productivity and stability at 35 degrees C compared to the normal study done at 30 degrees C. The increased number of cross flows diminish the product inhibition effect. The residence time distribution shows that the cross-flow bioreactor system can be approximated to either a train of backmixed fermentors in series or a plug flow fermentor with moderate axial dispersion.
Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, New Jersey 08854.
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Chotani
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Constantinides