Dioxirane mediated asymmetric epoxidations: stereochemical studies via isotopic labeling.
A study, via isotopic labeling, of the stereoselective processes in a Shi-type epoxidation, has revealed that the chiral platform provided by the catalyst mediates the transfer of the pro-S "O" of the related dioxirane species to the alkene in a doubly stereoselective manner.
Catalan Institution for Research and Advanced Studies (ICREA), Passeig Lluís Companys 23, 08018, Barcelona, Spain.
Natalia
N
Nieto
Ian J
IJ
Munslow
Jonathan
J
Barr
J
J
Benet-Buchholz
Anton
A
Vidal-Ferran