Diffusion resistance and enzyme activity decay in a pellet.
The effective enzyme activity decay can be decreased by diffusion limitation in the immobilized pellet. Thiele modulus changes and/or poisoning of various enzyme forms are two phenomena which are influenced by diffusion limitation. This article considers these effects on enzyme decay as applied to glucose isomerase.
Department of Chemical Engineering, West Virginia University, Morgantown, West Virginia.
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Verhoff
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Goldstein