Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome.
OBJECTIVE
To describe the clinical course of a case of intravascular lymphoma.


METHODS
Case report.


METHODS
Retrospective chart review.


RESULTS
A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.


CONCLUSIONS
Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.
Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts 01805, USA.
Patricia J
PJ
Pahk
Derrick J
DJ
Todd
Gregory R
GR
Blaha
Sarkis H
SH
Soukiasian
Dan S
DS
Landmann
Donald E
DE
Craven
Bruce S
BS
Tronic
Yuval
Y
Zabar
Jeffrey L
JL
Marx
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D058846:Antibodies, Monoclonal, Murine-Derived; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001808:Blood Vessels / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000627:therapeutic use; D005451:Fluorescein Angiography; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008223:Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D000069283:Rituximab; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis*; D019043:Vascular Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000201:enzymology; D014750:Vincristine / Q000627:therapeutic use; D014786:Vision Disorders / Q000209:etiology
D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; D007770:L-Lactate Dehydrogenase