Neurobiological correlates of coping through emotional approach.
This investigation considered possible health-related neurobiological processes associated with "emotional approach coping" (EAC), or intentional efforts to identify, process, and express emotions surrounding stressors. It was hypothesized that higher dispositional use of EAC strategies would be related to neural activity indicative of greater trait approach motivational orientation and to lower proinflammatory cytokine and cortisol responses to stress. To assess these relationships, 46 healthy participants completed a questionnaire assessing the two components of EAC (i.e., emotional processing and emotional expression), and their resting frontal cortical asymmetry was measured using electroencephalography (EEG). A subset (N=22) of these participants' levels of the soluble receptor for tumor necrosis factor-alpha (sTNFalphaRII), interleukin-6 (IL-6), and cortisol (all obtained from oral fluids) were also assessed before and after exposure to an acute laboratory stressor. Consistent with predictions, higher reported levels of emotional expression were significantly associated with greater relative left-sided frontal EEG asymmetry, indicative of greater trait approach motivation. Additionally, people who scored higher on EAC, particularly the emotional processing component, tended to show a less-pronounced TNF-alpha stress response. EAC was unrelated to levels of IL-6 and cortisol. Greater left-sided frontal EEG asymmetry was significantly related to lower baseline levels of IL-6 and to lower stress-related levels of sTNFalphaRII, and was marginally related to lower stress-related levels of IL-6. The findings suggest that the salubrious effects of EAC strategies for managing stress may be linked to an approach-oriented neurocognitive profile and to well-regulated proinflammatory cytokine responses to stress.
Master
Sarah L
SL
Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Los Angeles, CA 90095-1563, USA.
Amodio
David M
DM
Stanton
Annette L
AL
Yee
Cindy M
CM
Hilmert
Clayton J
CJ
Taylor
Shelley E
SE
D000293:Adolescent; D001931:Brain Mapping / Q000379:methods; D003863:Depression / Q000378:metabolism / Q000503:physiopathology / Q000523:psychology; D004569:Electroencephalography / Q000379:methods; D004644:Emotions / Q000502:physiology*; D005260:Female; D005625:Frontal Lobe / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis*; D007124:Immunoenzyme Techniques; D015850:Interleukin-6 / Q000032:analysis*; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011863:Radioimmunoassay; D012463:Saliva / Q000201:enzymology / Q000378:metabolism; D013315:Stress, Psychological / Q000378:metabolism / Q000503:physiopathology* / Q000523:psychology; D011795:Surveys and Questionnaires; D013647:Task Performance and Analysis; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*; D055815:Young Adult
D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D006854:Hydrocortisone