The Fokker-Planck approach for the cooperative molecular motor model with finite number of motors.
We provide the methodology for the analysis of the cooperative molecular motor model with finite number of motors, which are linearly and rigidly coupled, based on the Fokker-Planck approach. The probability density functions for the position of motors are solved numerically from the stationary Fokker-Planck equations. By using these probability density functions, we provide the analytical expressions, such as the velocity, the rate of the ATP consumption, the energetic efficiency, and the dissipation energy rates. Furthermore, we investigate three specific examples, such as single motor model, 2-motor model, and infinitely coupled motor model. Numerical algorithm to solve the Fokker-Planck equations is also provided.
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho Uji, Kyoto 611-0011, Japan.
Kazunari
K
Mouri
Tetsuya
T
Shimokawa
D020342:Finite Element Analysis; D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000737:chemistry* / Q000378:metabolism*; D011336:Probability
D020409:Molecular Motor Proteins