Biotransformation of beta-amyrin acetate by Rhodobacter sphaeroides.
The microbial transformation of beta-amyrin acetate (compound 1) occurred in the culture of Rhodobacter sphaeroides producing three metabolites. The metabolites were purified and identified as beta-amyrin (compound 2), (3beta)-olean-12-ene-3, 23-diol (compound 3), and erythrodiol (compound 4). Initially, it was found that beta-amyrin acetate could be deacetylated and hydroxylated by microbial methods.
College of Life Science and Technology, Shanxi University, Taiyuan, PR China.
Guan-E
GE
Yang
Zhaoming
Z
Zhang
Hongjun
H
Bai
Jun
J
Gong
Yufen
Y
Wang
Baozhen
B
Li
Jiankuan
J
Li
D019149:Bioreactors / Q000382:microbiology*; D001711:Biotransformation; D018929:Cell Culture Techniques / Q000379:methods*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D012242:Rhodobacter sphaeroides / Q000378:metabolism*
D009828:Oleanolic Acid; C000265:beta-amyrin acetate