Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.
The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through blood smear examination. These animals were divided into two groups i.e. A and B. Horses of Group A, were treated with diminazene diaceturate, while horses of Group B were treated with diminazene aceturate. Efficacy of the drugs was determined by the reversal of clinical signs and a negative blood smear examination. The efficacy of diminazene diaceturate was demonstrated to be 80% while diminazene aceturate was found to have 90% efficacy against babesiosis.
Rashid
Hamad Bin
HB
Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Chaudhry
Mamoona
M
Rashid
Haroon
H
Pervez
Khalid
K
Khan
Muhammad Arif
MA
Mahmood
Asim Khalid
AK
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001403:Babesia / Q000254:growth & development*; D001404:Babesiosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D004133:Diminazene / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology*; D006736:Horses; D008297:Male
D000981:Antiprotozoal Agents; C003915:diminazene aceturate; D004133:Diminazene