Golgi governance: the third way.
It is a subject of intense debate whether proteins are transported by vesicles through the membranous stacks of the Golgi or whether the stacks mature, carrying the cargo along. In this issue, Patterson et al. (2008) present evidence for a third model in which the Golgi stacks are a continuous structure and proteins rapidly equilibrate between the layers.
Simon
Sanford M
SM
Laboratory of Cellular Biophysics, The Rockefeller University, New York, NY 10021, USA. simon@mail.rockefeller.edu
D000818:Animals; D006056:Golgi Apparatus / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D021381:Protein Transport