Atlantic salmon (Salmo salar L.) parr fed genetically modified soybeans and maize: Histological, digestive, metabolic, and immunological investigations.
Physiological and health related responses to dietary inclusion of genetically modified (GM) full-fat soybean meal (Roundup Ready; GM-soy) and maize (MON810 Bt-maize; GM-maize), as well as non-parental, untransformed lines (nGM-soy and nGM-maize D2), were evaluated in farmed Atlantic salmon (Salmo salar L.) parr during the first 8 months of feeding. Significant effects of dietary GM presence were only found in intestinal Na+-dependent d-glucose uptake and SGLT1 protein level in the region pyloric caeca in which the highest values were found in the GM-soy, intermediate in the nGM-soy, and lowest in the standard FM fed groups. Data from this study confirm that GM soybeans (RRS) and maize (MON810) at inclusion levels of about 6% appear to be as safe as commercially available nGM soy and maize in diets for Atlantic salmon parr. Results from studies with higher inclusion levels and with non-modified, isogenic or near-isogenic parental lines as control groups are pending.
Aquaculture Protein Centre (APC), CoE, Norway. anne.mckellep@veths.no
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Bakke-McKellep
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Sanden
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Danieli
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Acierno
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Hemre
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Maffia
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Krogdahl
D000821:Animal Feed; D000818:Animals; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D004063:Digestion / Q000502:physiology*; D030841:Food, Genetically Modified; D007107:Immune System / Q000187:drug effects*; D007075:Immunoglobulin M / Q000097:blood / Q000187:drug effects; D020317:Salmo salar / Q000254:growth & development* / Q000276:immunology; D013025:Glycine max / Q000235:genetics; D003313:Zea mays / Q000235:genetics
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D007075:Immunoglobulin M