Cu+ -ATPases brake system.
Copper (Cu+) transport ATPases are characterized by cytoplasmic metal-binding repeats. Using cryo-electron microscopy (cryo-EM) of functionally intact Cu+-ATPases and high-resolution structures of isolated domains, Wu et al. (2008) produced a model that explains how Cu+ binding to cytoplasmic sites controls the enzyme transport rate.
José M
JM
Argüello
Manuel
M
González-Guerrero
D000251:Adenosine Triphosphatases / Q000737:chemistry*; D027682:Cation Transport Proteins / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D000073840:Copper-Transporting ATPases; D020285:Cryoelectron Microscopy; D008958:Models, Molecular; D017434:Protein Structure, Tertiary
D027682:Cation Transport Proteins; D003300:Copper; D000251:Adenosine Triphosphatases; D000073840:Copper-Transporting ATPases