Outbreak of chikungunya due to virus of Central/East African genotype in Malaysia.
Chikungunya is an acute febrile illness caused by an alphavirus which is transmitted by infective Aedes mosquitoes. Two previous outbreaks of chikungunya in Malaysia were due to chikungunya virus of Asian genotype. The present outbreak involved two adjoining areas in the suburb of Ipoh city within the Kinta district of Perak, a state in the northern part of Peninsular Malaysia. Thirty seven residents in the main outbreak area and two patients in the secondary area were laboratory confirmed to be infected with the virus. The index case was a 44-year Indian man who visited Paramakudi, Tamil Naidu, India on 21st November 2006 and returned home on 30th of November 2006, and subsequently developed high fever and joint pain on the 3rd of December 2006. A number of chikungunya virus isolates were isolated from both patients and Aedes albopictus mosquitoes in the affected areas. Molecular study showed that the chikungunya virus causing the Kinta outbreak was of the Central/East African genotype which occurred for the first time in Malaysia.
Noridah
O
O
Pejabat Kesihatan Daerah Kinta, 30000 Batu Gajah, Perak, Malaysia.
Paranthaman
V
V
Nayar
S K
SK
Masliza
M
M
Ranjit
K
K
Norizah
I
I
Chem
Y K
YK
Mustafa
B
B
Kumarasamy
V
V
Chua
K B
KB
D000293:Adolescent; D000328:Adult; D018354:Alphavirus Infections / Q000453:epidemiology* / Q000235:genetics / Q000635:transmission; D000818:Animals; D002646:Chikungunya virus / Q000235:genetics* / Q000302:isolation & purification; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D005838:Genotype; D006306:Health Surveys; D006801:Humans; D007194:India / Q000453:epidemiology; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D036301:Qualitative Research; D012698:Serologic Tests