Formal total synthesis of (-)-haouamine A.
A largely catalysis based approach to optically active haouamine A (-)-1 is presented, which provides the hexacyclic compound previously used to construct this cytotoxic marine alkaloid.
Fürstner
Alois
A
Max-Planck-Institut für Kohlenforschung, D-45470, Mülheim/Ruhr, Germany. fuerstner@mpi-muelheim.mpg.de
Ackerstaff
Jens
J
D018360:Crystallography, X-Ray; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D000097566:Cyclophanes
D006576:Heterocyclic Compounds, 4 or More Rings; C474767:haouamine A; D000097566:Cyclophanes