Hybrid neurofibroma-schwannoma of the orbit.
OBJECTIVE
To report a case of an unusual orbital tumor with histologic features of both neurofibroma and schwannoma.


METHODS
Clinical and pathological findings are presented in a patient with an orbital tumor.


RESULTS
Orbital magnetic resonance imaging in a 51-year-old female revealed a heterogeneously enhancing right orbital mass. An anterior orbitotomy was performed, and pathological evaluation revealed a tumor with discrete areas of both neurofibroma and schwannoma.


CONCLUSIONS
Hybrid neurofibroma-schwannomas may arise within the orbit.
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27713, USA. kenneth.youens@duke.edu
Kenneth E
KE
Youens
Julie
J
Woodward
Dana
D
Wallace
Thomas J
TJ
Cummings
D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D009455:Neurofibroma / Q000473:pathology* / Q000601:surgery; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D009915:Orbit / Q000601:surgery*; D009918:Orbital Neoplasms / Q000473:pathology* / Q000601:surgery; D018570:Risk Assessment; D016896:Treatment Outcome