Updates on high-throughput molecular profiling for the study of rheumatoid arthritis.
The completion of the human genome mapping project has provided the necessary backdrop for the development of high-throughput array technologies. In contrast to the reductionist approach to studying the role of a particular molecule in a specific pathway, these technologies enable us to conduct a comprehensive survey of various molecular profiles across different cell types and individuals, placing us one step closer to understanding integrative regulatory networks and the workings of the cell as a whole.
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Laura F
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Department of Medicine, Division of Immunology and Rheumatology, Stanford, CA 94305, USA. laurasu@stanford.edu
D001172:Arthritis, Rheumatoid / Q000235:genetics* / Q000276:immunology; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000639:trends*; D040901:Proteomics