Facilitated transport of penicillin G by bulk liquid membrane with TBP as carrier.
The facilitated transport of penicillin G from aqueous solutions to the stripping phase through bulk liquid membrane (BLM) containing TBP in 3% iso-octanol and n-butyl acetate was studied. Na(2)CO(3) solution was used as the stripping phase. Experiments were performed as a function of stirring rate, TBP concentration and type of diluent in the liquid membrane phase, pH, and initial penicillin G concentration in the feed phase, Na(2)CO(3) concentration in the stripping phase, etc. The results showed that the BLM process could carry out the simultaneous separation and concentration of penicillin G from dilute aqueous solutions, and arise "up-hill" effect due to the characteristic of non-equilibrium mass transfer. The diffusion of penicillin G complex in the liquid membrane phase played an important role in BLM process. The mass transfer mechanism of BLM for this system was also discussed.
Ren
Zhongqi
Z
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Lv
Yuanyuan
Y
Zhang
Weidong
W
D000085:Acetates / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008567:Membranes, Artificial; D010755:Organophosphates / Q000737:chemistry*; D010400:Penicillin G / Q000737:chemistry* / Q000302:isolation & purification*; D013997:Time Factors
D000085:Acetates; D002254:Carbonates; D008567:Membranes, Artificial; D010755:Organophosphates; C005686:sodium carbonate; C006848:butyl acetate; C009524:tributyl phosphate; D010400:Penicillin G