2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines.
Microwave irradiations of 2-(aminoaryl)alkanone O-phenyl oximes and carbonyl compounds generate iminyl radicals in company with imines; iminyl on imine ring closure yields dihydroquinazolines or quinazolines when ZnCl2 is included in the mixture.
University of St. Andrews, School of Chemistry, EaStChem, St. Andrews, Fife, UK KY16 9ST.
Fernando
F
Portela-Cubillo
Jackie S
JS
Scott
John C
JC
Walton
D000473:Alkanes / Q000737:chemistry*; D000586:Amination; D002712:Chlorides / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
D000473:Alkanes; D002712:Chlorides; D007202:Indicators and Reagents; D010091:Oximes; D011799:Quinazolines; D017967:Zinc Compounds; C016837:zinc chloride