Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac.
Neutron production is an unwanted result of high-energy radiation therapy and results in secondary exposure of patients and radiation therapists to radiation. Recent studies have shown that delivering therapy using a standard medical accelerator with the flattening filter removed may reduce neutron fluence by nearly 70% over the course of prostate intensity-modulated radiation therapy (IMRT). In the current study, the 197Au Bonner sphere technique was used to compare the neutron spectrum produced when the filter is present and when it is absent. In addition, the following was calculated: (1) the neutron-shielding parameters of source strength and ambient dose equivalent (H0) and (2) using the Monte Carlo technique, the sources of neutron production in the accelerator head. It was found that the neutron spectrum was nearly constant, regardless of the presence of the flattening filter; however, the total fluence and ambient dose equivalent over the course of prostate IMRT were more than 70% lower when the filter was removed. Similarly, shielding parameters were lower when the filter was removed. Finally, the primary collimator and jaws accounted for the majority of neutron production, both with and without the flattening filter; however, with the flattening filter removed, the upper jaw accounted for much more neutron production relative to when the filter was present. Ultimately, removal of the flattening filter may offer several clinical advantages, including a reduction in the dose from neutrons to the patient and to radiation personnel.
Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. sfkry@mdanderson.org
Stephen F
SF
Kry
Rebecca M
RM
Howell
Uwe
U
Titt
Mohammad
M
Salehpour
Radhe
R
Mohan
Oleg N
ON
Vassiliev
D000465:Algorithms; D004867:Equipment Design; D006801:Humans; D008297:Male; D009010:Monte Carlo Method; D009502:Neutrons; D010315:Particle Accelerators; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D012542:Scattering, Radiation; D012984:Software