[Prepared evening primrose oil microspheres by spray drying].
OBJECTIVE
To explore the best technique parameters on preparing evening primrose oil microspheres by spray drying technique.


METHODS
GC and internal standard method were used to determine the content of gamma-linolenic acid methyl esters, the technological parameters were investigated by orthogonal experimental design with the yield and entrapment rate as indexes.


RESULTS
The charging rate as 3 mL x min(-1), atomizing pressure as 100 kPa and the temperature of inlet as 105 degrees C were the best technique parameters.


CONCLUSIONS
Evening primrose oil microspheres accorded with the expecting demand. The main influencing factor is the charging rate. Spray drying is reasonable and practical for preparing evening primrose oil microspheres.
Guo
Jian-Peng
JP
College of Pharmacy, Yanbian University, Yanji 133000, China. gjp807@ybu.edu.cn
Xue
Hong
H
D002849:Chromatography, Gas; D005240:Feasibility Studies; D016014:Linear Models; D008863:Microspheres; D031665:Oenothera biennis / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017965:gamma-Linolenic Acid / Q000032:analysis
D010938:Plant Oils; D017965:gamma-Linolenic Acid