title: Follicular dendritic cell sarcoma of the head and neck: case report and literature review.
abstract: OBJECTIVE
  This article presents a case of a patient with follicular dendritic cell sarcoma (FDS), a rare neoplasm usually of the head and neck, and reviews the literature.
  
  
  METHODS
  Literature review.
  
  
  METHODS
  A MEDLINE literature search was performed and the literature was reviewed.
  
  
  RESULTS
  Our patient presented with an FDS that had been excised from the upper neck and recurred in a level V node. He was treated with neck dissection and postoperative irradiation and remains disease free 5.25 years after salvage treatment. The literature search yielded 67 case reports on FDS of the head and/or neck. Most patients were treated with surgery (94%). Twenty-eight percent of patients received adjuvant radiotherapy; 18% received adjuvant chemotherapy. Fifty percent of patients were alive with no evidence of disease at last follow-up; 9% died from disease.
  
  
  CONCLUSIONS
  We currently treat head and neck FDS with wide resection and postoperative radiotherapy.
authors.affiliation: Departments of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
authors.forename: Bhishamjit S
authors.initials: BS
authors.lastname: Chera
authors.forename: Christine
authors.initials: C
authors.lastname: Orlando
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Villaret
authors.forename: William M
authors.initials: WM
authors.lastname: Mendenhall
mesh_terms: D044963:Biopsy, Fine-Needle; D020566:Dendritic Cells, Follicular / Q000473:pathology*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed