[Chemical constituents of the spores of Ganoderma lucidum].
OBJECTIVE
To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum.


METHODS
Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data.


RESULTS
From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively.


CONCLUSIONS
Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.
Zhang
Xiao-qi
XQ
Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
Pang
Guo-liang
GL
Cheng
Yan
Y
Wang
Ying
Y
Ye
Wen-cai
WC
D004875:Ergosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D032902:Ganoderma / Q000737:chemistry*; D006538:Heptanoic Acids / Q000737:chemistry / Q000302:isolation & purification; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013172:Spores, Fungal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006538:Heptanoic Acids; D014315:Triterpenes; D007810:Lanosterol; C515005:ganoderic acid A; C036071:ergosterol-5,8-peroxide; D004875:Ergosterol