title: Bridge to transplantation with a Toyobo-NCVC left ventricular assist device in a 3-year-old girl.
abstract: In Japan, no pulsatile ventricular assist devices are available specifically for use in children. Pumps designed for adults are thus often used in children. We report herein a case of end-stage heart failure in a 3-year old girl (height 100.4 cm; body weight 16.2 kg; body surface area 0.66 m2) who underwent implantation with an adult-sized Toyobo-NCVC left ventricular assist device (Toyobo-National Cardiovascular Center, Osaka, Japan) in our unit. We started with the driving mode to "full-fill, full-empty" mode. The problem was difficult-to-treat hypertension due to excessive stroke volume induced by the left ventricular assist device. Aggressive administration of antihypertensive therapy was needed. Successful heart transplantation was performed in Germany 5 months after beginning support with the Toyobo-NCVC left ventricular assist device.
authors.affiliation: Department of Pediatric Cardiac Surgery, Saitama University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, Japan. masuoka@saitama-med.ac.jp
authors.forename: Ayumu
authors.initials: A
authors.lastname: Masuoka
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Katogi
authors.forename: Mika
authors.initials: M
authors.lastname: Iwazaki
authors.forename: Toshiki
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishimura
authors.forename: Shunei
authors.initials: S
authors.lastname: Kyo
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D002311:Cardiomyopathy, Dilated / Q000150:complications* / Q000473:pathology / Q000628:therapy; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000209:etiology / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010166:Palliative Care; D011474:Prosthesis Design; D013902:Radiography, Thoracic; D013318:Stroke Volume; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents