title: Reach of benchmark psychiatric trial results to community-based providers: a case study of CATIE.
abstract: OBJECTIVE
  To evaluate the familiarity of front-line clinicians with findings from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE), the influence of didactic continuing medical education on provider knowledge about key details of CATIE, and how location-related factors affect rates of pre-event knowledge and intraevent learning about CATIE.
  
  
  METHODS
  Data derived from the Massachusetts General Hospital Psychiatry Academy (MGH-PA) semester II live symposia provided in different cities nationally between September and December 2006 were analyzed to evaluate providers' self-assessment of their knowledge about CATIE. In addition, participants were also asked a preactivity and postactivity question to assess learning of material presented during the live event psychosis lecture. Descriptive statistics were utilized to characterize participants' self-assessment of knowledge about CATIE, while parametric and nonparametric statistical tests were used to evaluate the degree of observed learning and the effect of lecture location on the results.
  
  
  RESULTS
  3333 participants (mean attendance: N = 278 per event) attended 1 of the 12 MGH-PA live symposia. Of the subsample of providers who treat schizophrenia, 51% indicated that either they had never heard of CATIE or they were not familiar enough with its results to change their practice. Overall, the proportion of correct answers on the postactivity question was 65%, compared with 24% prior to the lecture (chi(2) = 48.68, df = 1, p < .001). Degree of learning did not differ among symposium locations.
  
  
  CONCLUSIONS
  In this sample, the CATIE study had very limited dissemination to, and impact on, a geographically and occupationally diverse sample of mental health practitioners. Robust learning of a key methodologic detail of this trial was evidenced across symposium locations.
authors.affiliation: Massachusetts General Hospital Department of Psychiatry, Division of Postgraduate Education, Boston, MA 02114, USA. tpetersen@partners.org
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Petersen
authors.forename: Jeff C
authors.initials: JC
authors.lastname: Huffman
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Weiss
authors.forename: Mark A
authors.initials: MA
authors.lastname: Blais
authors.forename: Charissa F
authors.initials: CF
authors.lastname: Andreotti
authors.forename: Madeline B
authors.initials: MB
authors.lastname: Horwitz
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Birnbaum
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001364:Awareness; D019985:Benchmarking / Q000706:statistics & numerical data*; D002983:Clinical Competence; D003156:Community Mental Health Services / Q000706:statistics & numerical data*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D011570:Psychiatry / Q000706:statistics & numerical data*; D012559:Schizophrenia / Q000188:drug therapy* / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents