title: Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target.
abstract: The Japan Atherosclerosis Society (JAS) guidelines for the prevention of atherosclerotic diseases, proposing management for LDL cholesterol as the primary target, have successfully contributed to the prevention of cardiovascular events; however, recently, the impact of hypertriglyceridemia as an additional cardiovascular risk has become understood, especially in light of the rise in obesity, metabolic syndrome, and diabetes in the Japanese population. Rather than waiting to obtain conclusive domestic data confirming that hypertriglyceridemia is a cardiovascular risk factor and that its management is efficacious, we propose guidelines for hypertriglyceridemia using non-HDL cholesterol as a second target.
authors.affiliation: The Research Committee for Primary Hyperlipidemia, Research on Measures for Intractable Diseases by the Ministry for Health, Labor, and Welfare in Japan. shimano-tky@umin.ac.jp
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Shimano
authors.forename: Hidenori
authors.initials: H
authors.lastname: Arai
authors.forename: Mariko
authors.initials: M
authors.lastname: Harada-Shiba
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Ueshima
authors.forename: Takao
authors.initials: T
authors.lastname: Ohta
authors.forename: Shizuya
authors.initials: S
authors.lastname: Yamashita
authors.forename: Takanari
authors.initials: T
authors.lastname: Gotoda
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kiyohara
authors.forename: Toshio
authors.initials: T
authors.lastname: Hayashi
authors.forename: Junji
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Shimamoto
authors.forename: Hideaki
authors.initials: H
authors.lastname: Bujo
authors.forename: Shun
authors.initials: S
authors.lastname: Ishibashi
authors.forename: Koji
authors.initials: K
authors.lastname: Shirai
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oikawa
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Saito
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yamada
mesh_terms: D050197:Atherosclerosis / Q000517:prevention & control; D015415:Biomarkers / Q000378:metabolism; D002309:Cardiology / Q000592:standards*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000473:pathology; D002784:Cholesterol / Q000378:metabolism; D008076:Cholesterol, HDL / Q000378:metabolism; D008078:Cholesterol, LDL / Q000378:metabolism*; D050171:Dyslipidemias / Q000175:diagnosis / Q000517:prevention & control; D017408:Guidelines as Topic; D006801:Humans; D015228:Hypertriglyceridemia / Q000517:prevention & control* / Q000628:therapy*; D007564:Japan; D008055:Lipids / Q000737:chemistry; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D002784:Cholesterol