title: The effect of structured exercise classes and a lifestyle intervention on cardiovascular risk factors in primary schoolchildren: an exploratory trial (The A-CLASS Project).
abstract: This exploratory trial evaluates the effect of a structured exercise (STEX) or lifestyle intervention (PASS) program upon cardiovascular (CV) disease risk factors in children. Sixty-one schoolchildren were randomly assigned by school to an intervention or control (CON) condition. The effect of the STEX (compared with CON) was a mean benefit of -0.018 mm for average maximum carotid intimamedia thickness. The PASS intervention did not result in clinically important effects, and no other substantial changes were observed. Relatively high probability of clinically beneficial effects of the STEX intervention suggests that a larger, definitive randomized trial with longer follow-up is warranted.
authors.affiliation: Research Institute for Sport and Exercise Scnences (REACH Group), Liverpool John Moores University, UK.
authors.forename: Jayne
authors.initials: J
authors.lastname: Henaghan
authors.forename: Nicola
authors.initials: N
authors.lastname: McWhannell
authors.forename: Lawrence
authors.initials: L
authors.lastname: Foweather
authors.forename: N Tim
authors.initials: NT
authors.lastname: Cable
authors.forename: Alan M
authors.initials: AM
authors.lastname: Batterham
authors.forename: Gareth
authors.initials: G
authors.lastname: Stratton
authors.forename: Keith P
authors.initials: KP
authors.lastname: George
mesh_terms: D000886:Anthropometry; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002339:Carotid Arteries / Q000473:pathology; D002648:Child; D015444:Exercise; D005260:Female; D006266:Health Education / Q000379:methods*; D006293:Health Promotion; D006801:Humans; D008019:Life Style; D008297:Male; D009043:Motor Activity; D010865:Pilot Projects; D015397:Program Evaluation; D012307:Risk Factors; D012574:Schools; D040241:Social Marketing; D013334:Students; D017539:Tunica Intima / Q000473:pathology