title: Precise reporting of traditional Chinese medicine interventions in randomized controlled trials.
abstract: Traditional Chinese medicine (TCM) intervention should be concisely and precisely reported in randomized controlled trials (RCTs). Based on State Food and Drug Administration's categories, we recommend reporting the interventions as follows: (1) Single Chinese herbal medicine-based/formula-based/extraction-based intervention includes 1) Name, dosage format and registration; 2) The composition and quality of intervention; 3) Pharmaceutical processing and quality control; 4) Stability of final product and quality control; 5) Function and safety description; 6) Dosage and treatment course; 7) Control group. (2) Active compound-based TCM drug intervention includes 1) Name of active compound(s); 2) Original source of active compound(s); 3) The brief process obtaining active compound(s); 4) Percentage of active compound(s) in final product; 5) Added materials and its quality and quantity control. Besides, the detailed information of intervention can be published as an online supplement in web site.
authors.forename: Zhao-xiang
authors.initials: ZX
authors.lastname: Bian
authors.forename: David
authors.initials: D
authors.lastname: Moher
authors.forename: You-ping
authors.initials: YP
authors.lastname: Li
authors.forename: Tai-xiang
authors.initials: TX
authors.lastname: Wu
authors.forename: Simon
authors.initials: S
authors.lastname: Dagenais
authors.forename: Chung-wah
authors.initials: CW
authors.lastname: Cheng
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Ting-qian
authors.initials: TQ
authors.lastname: Li
mesh_terms: D004365:Drugs, Chinese Herbal / Q000592:standards* / Q000627:therapeutic use; D019317:Evidence-Based Medicine; D008516:Medicine, Chinese Traditional / Q000592:standards*; D010506:Periodicals as Topic; D011643:Publishing / Q000592:standards*; D016032:Randomized Controlled Trials as Topic / Q000592:standards*; D012107:Research Design
chemical_list: D004365:Drugs, Chinese Herbal