Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1.
A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.
Santivañez
Saul J
SJ
Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru.
Gutierrez
Ariana M
AM
Rosenzvit
Mara C
MC
Muzulin
Patricia M
PM
Rodriguez
Mary L
ML
Vasquez
Julio C
JC
Rodriguez
Silvia
S
Gonzalez
Armando E
AE
Gilman
Robert H
RH
Garcia
Hector H
HH
D000818:Animals; D002162:Camelus / Q000469:parasitology*; D018509:DNA, Helminth / Q000032:analysis / Q000737:chemistry*; D004272:DNA, Mitochondrial / Q000032:analysis / Q000737:chemistry*; D004285:Dogs; D004443:Echinococcosis; D048209:Echinococcus granulosus / Q000145:classification* / Q000201:enzymology / Q000235:genetics; D003576:Electron Transport Complex IV / Q000235:genetics*; D005838:Genotype; D006801:Humans; D010568:Peru / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology; D015047:Zoonoses / Q000453:epidemiology / Q000469:parasitology* / Q000635:transmission
D018509:DNA, Helminth; D004272:DNA, Mitochondrial; D003576:Electron Transport Complex IV