title: Coping and quality of life in patients awaiting lung transplantation.
abstract: OBJECTIVE
  Patients with end-stage lung disease (ESLD) experience significant decrements in quality of life (QOL). Although coping strategies are related to QOL in patients with ESLD, the extent to which specific native lung disease moderates this relationship is unknown.
  
  
  METHODS
  We investigated the relationship between coping, native lung disease, and QOL among 187 patients awaiting lung transplantation, including 139 patients with chronic obstructive pulmonary disease (COPD) and 48 with cystic fibrosis (CF). Participants completed a psychosocial battery assessing psychological QOL, physical QOL, and coping strategies.
  
  
  RESULTS
  For both COPD and CF patients, higher levels of Active Coping (P< .0001) and lower levels of Disengagement (P< .0001) were associated with better psychological QOL. For physical QOL, we observed a Native Disease x Coping interaction (P=.01) such that Active Coping was associated with better physical QOL in patients with COPD but not in patients with CF.
  
  
  CONCLUSIONS
  The relationship between coping and QOL may vary as a function of native lung disease. Patients' native disease may need to be considered in order to develop effective interventions to help patients cope successfully with ESLD.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27710, USA.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Taylor
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Smith
authors.forename: Michael A
authors.initials: MA
authors.lastname: Babyak
authors.forename: Krista A
authors.initials: KA
authors.lastname: Barbour
authors.forename: Benson M
authors.initials: BM
authors.lastname: Hoffman
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Sebring
authors.forename: R Duane
authors.initials: RD
authors.lastname: Davis
authors.forename: Scott M
authors.initials: SM
authors.lastname: Palmer
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Keefe
authors.forename: Robert M
authors.initials: RM
authors.lastname: Carney
authors.forename: Iris
authors.initials: I
authors.lastname: Csik
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Freedland
authors.forename: James A
authors.initials: JA
authors.lastname: Blumenthal
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000523:psychology* / Q000601:surgery; D004644:Emotions; D005260:Female; D006304:Health Status; D006801:Humans; D007389:Internal-External Control; D016040:Lung Transplantation / Q000523:psychology* / Q000534:rehabilitation; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D025341:Principal Component Analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000523:psychology* / Q000601:surgery; D011788:Quality of Life; D018434:Sickness Impact Profile; D013315:Stress, Psychological / Q000175:diagnosis / Q000523:psychology; D011795:Surveys and Questionnaires