Supported phospholipid membrane interactions with 1-butyl-3-methylimidazolium chloride.
Quartz crystal microbalance with dissipation measurements were conducted for a 98/2 mole ratio of 1,2-dielaidoylphosphocholine (DEPC) and 1,2-dimyristoylphosphoglycerol (DMPG) on silica, gold, and a self-assembled monolayer of 11-mercapto-1-undecanol (11MU) and 11-mercaptoundecanoic acid (11MUA) at 50 mol % each. This study demonstrates that vesicles composed of DEPC and DMPG at 98 and 2 mol %, respectively, formed a supported bilayer with unruptured vesicles present when adsorbed onto the self-assembled monolayer. Also, the partially formed supported bilayer apparently deadsorbed in the presence of 1-butyl-3-methylimidazolium chloride, suggesting that surface-bilayer interactions are weaker on a hydrophilic modified gold surface composed of 50/50 11MU/11MUA than the surface-bilayer interactions on silica.
Evans
Kervin O
KO
New Crops and Processing Technology Research Unit, United States Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research, Peoria, Illinois 61604, USA. Kervin.Evans@ars.usda.gov
D005227:Fatty Acids / Q000737:chemistry; D005233:Fatty Alcohols / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D010715:Phosphatidylglycerols / Q000737:chemistry; D010743:Phospholipids / Q000737:chemistry*; D010767:Phosphorylcholine / Q000031:analogs & derivatives; D012822:Silicon Dioxide / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors
C505222:11-mercaptoundecanoic acid; D005227:Fatty Acids; D005233:Fatty Alcohols; D007093:Imidazoles; D008051:Lipid Bilayers; D010715:Phosphatidylglycerols; D010743:Phospholipids; D013438:Sulfhydryl Compounds; D010767:Phosphorylcholine; C502841:1-butyl-3-methylimidazolium chloride; D006046:Gold; D012822:Silicon Dioxide; C002773:dimyristoylphosphatidylglycerol