title: Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.
authors.forename: Kenichi A
authors.initials: KA
authors.lastname: Tanaka
authors.forename: Andras
authors.initials: A
authors.lastname: Gruber
authors.forename: Fania
authors.initials: F
authors.lastname: Szlam
authors.forename: Leslie A
authors.initials: LA
authors.lastname: Bush
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Hanson
authors.forename: Enrico
authors.initials: E
authors.lastname: Di Cera
mesh_terms: D019943:Amino Acid Substitution; D000925:Anticoagulants / Q000737:chemistry; D001120:Arginine / Q000031:analogs & derivatives; D004791:Enzyme Inhibitors / Q000737:chemistry*; D005340:Fibrinogen / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D020125:Mutation, Missense; D010875:Pipecolic Acids / Q000737:chemistry*; D011485:Protein Binding / Q000235:genetics; D011486:Protein C / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary / Q000235:genetics; D013449:Sulfonamides; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism
chemical_list: D000925:Anticoagulants; D004791:Enzyme Inhibitors; D010875:Pipecolic Acids; D011486:Protein C; D013449:Sulfonamides; D005340:Fibrinogen; D001120:Arginine; D013917:Thrombin; C031942:argatroban