title: Organozinc reagents in DMSO solvent: remarkable promotion of SN2' reaction for allene synthesis.
abstract: The S N2' reaction of propragyl mesylates with organozinc reagents was dramatically improved in DMSO solvent, and the stereoselective conversion of chiral substrates was successfully achieved using LiCl-free diorganozinc without the loss of optical purity.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki-aza Aoba 6-3, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naka
authors.forename: Andrew E H
authors.initials: AE
authors.lastname: Wheatley
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo
mesh_terms: D000466:Alkadienes / Q000138:chemical synthesis*; D000480:Alkynes / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D000466:Alkadienes; D000480:Alkynes; D008698:Mesylates; D009942:Organometallic Compounds; C025947:propadiene; D015032:Zinc; D004121:Dimethyl Sulfoxide