Biotransformation of zerumbone by Caragana chamlagu.
Suspension cultured cells of Caragana chamlagu (Leguminosae) converted zerumbone (1) into zerumbone epoxide (2) as the intermediate, (2R,3R,7R)-2,3-epoxy-9-humulen-8-one (3) and (2R,3S,7R)-2,3-epoxy-9-humulen-8-one (4) as new sesquiterpenes in 11%, 36% and 21% yields, respectively.
Sakamaki
Hiroshi
H
College of Science and Technology, Nihon University, 7-24-1 Narashinodai, Funabashi-shi, Chiba, 274-8501, Japan. sakamaki@chem.ge.cst.nihon-u.ac.jp
Itoh
Ken-Ichi
K
Kitanaka
Susumu
S
Sawada
Seiji
S
Horiuchi
C Akira
CA
D001711:Biotransformation; D032602:Caragana / Q000166:cytology / Q000378:metabolism*; D013058:Mass Spectrometry; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000378:metabolism*
D012717:Sesquiterpenes; C403304:zerumbone