Follicular dendritic cell sarcoma of the head and neck: case report and literature review.
OBJECTIVE
This article presents a case of a patient with follicular dendritic cell sarcoma (FDS), a rare neoplasm usually of the head and neck, and reviews the literature.


METHODS
Literature review.


METHODS
A MEDLINE literature search was performed and the literature was reviewed.


RESULTS
Our patient presented with an FDS that had been excised from the upper neck and recurred in a level V node. He was treated with neck dissection and postoperative irradiation and remains disease free 5.25 years after salvage treatment. The literature search yielded 67 case reports on FDS of the head and/or neck. Most patients were treated with surgery (94%). Twenty-eight percent of patients received adjuvant radiotherapy; 18% received adjuvant chemotherapy. Fifty percent of patients were alive with no evidence of disease at last follow-up; 9% died from disease.


CONCLUSIONS
We currently treat head and neck FDS with wide resection and postoperative radiotherapy.
Chera
Bhishamjit S
BS
Departments of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
Orlando
Christine
C
Villaret
Douglas B
DB
Mendenhall
William M
WM
D044963:Biopsy, Fine-Needle; D020566:Dendritic Cells, Follicular / Q000473:pathology*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed