Prenatal diagnosis of fetal hepatoblastoma: case report and review of the literature.
Hepatoblastoma is the most common liver malignancy in childhood. The reported incidence is 11.2 cases per 1 million during the first year of life. Genetic predispositions include Beckwith-Wiedemann syndrome and familial polyposis. The prognosis depends on the extent of tumor spreading at the time of initial treatment, which typically includes chemotherapy and surgery. Imaging of hepatoblastoma has only rarely been reported prenatally. Here we report a recent case with a successful outcome and discuss issues of differential diagnosis and treatment.
Catanzarite
Val
V
Department of Maternal-Fetal Medicine, Sharp Mary Birch Hospital for Women, and San Diego Perinatal Center, San Diego, California 92123, USA. vcatanza@gmail.com
Hilfiker
Mary
M
Daneshmand
Sean
S
Willert
Jennifer
J
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D018197:Hepatoblastoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color / Q000379:methods