title: Colorimetric discrimination between important alkaloid nuclei mediated by a bis-salphen chromophore.
abstract: A new colorimetric method is presented that allows for simple and effective discrimination between (iso)quinoline nuclei pertinent to many alkaloid species. The method is based on the reversible incorporation of Zn2+ ions into a bis-salphen chromophore under aqueous conditions. The metalation process is a function of the stability of the Zn-N (acceptor-donor) interaction and is accompanied by a clear colorimetric response.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Av. Paisos Catalans 16, 43007 Tarragona, Spain.
authors.forename: Sander J
authors.initials: SJ
authors.lastname: Wezenberg
authors.forename: Eduardo C
authors.initials: EC
authors.lastname: Escudero-Adán
authors.forename: Jordi
authors.initials: J
authors.lastname: Benet-Buchholz
authors.forename: Arjan W
authors.initials: AW
authors.lastname: Kleij
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D003124:Colorimetry / Q000379:methods*; D018360:Crystallography, X-Ray; D007546:Isoquinolines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013056:Spectrophotometry, Ultraviolet; D017967:Zinc Compounds / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D007546:Isoquinolines; D017967:Zinc Compounds