title: Fluorescent silica nanoparticles.
abstract: We report on the preparation of fluorescent silica nanoparticles (NPs). They have been prepared by (a) modification of the NPs by amino groups and subsequent introduction of amino-reactive fluorophores of various color and (b) by modification of the NPs by either azido groups or alkyne groups and subsequent conjugation to fluorophores by so-called click chemistry, which is a novel approach toward modifying silica NPs. The new NPs were characterized in terms of size and spectral properties.
authors.affiliation: Institute of Analytical Chemsitry, Chemo- and Biosensors, University of Regensburg, D-93040 Regensburg, Germany.
authors.forename: Heike
authors.initials: H
authors.lastname: Mader
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Li
authors.forename: Sayed
authors.initials: S
authors.lastname: Saleh
authors.forename: Martin
authors.initials: M
authors.lastname: Link
authors.forename: Peter
authors.initials: P
authors.lastname: Kele
authors.forename: Otto S
authors.initials: OS
authors.lastname: Wolfbeis
mesh_terms: D001681:Biological Assay / Q000295:instrumentation; D002713:Chlorine / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence / Q000379:methods*; D008956:Models, Chemical; D036103:Nanotechnology / Q000379:methods; D010316:Particle Size; D011437:Propylamines; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D005456:Fluorescent Dyes; D011437:Propylamines; D012821:Silanes; D002713:Chlorine; D012822:Silicon Dioxide; C477625:amino-propyl-triethoxysilane