title: The impact of nutrition intervention on quality of life in pre-dialysis chronic kidney disease patients.
abstract: OBJECTIVE
  Uraemic symptoms as a result of reduced kidney function may impact on an individual's functional and nutritional status. This study aims to investigate whether providing individualised nutritional counselling can improve nutritional status and influence quality of life in pre-dialysis chronic kidney disease patients.
  
  
  METHODS
  Fifty-three stage IV and V pre-dialysis chronic kidney disease patients underwent assessment of nutritional status (by Patient Generated Subjective Global Assessment) and quality of life (by Kidney Disease Quality of Life). Participants were assessed at baseline and following a 12-week randomised-controlled treatment, allocated to either individualised counselling with regular follow-up (n=24) or standard care treatment (generic education only (n=23)).
  
  
  RESULTS
  At baseline, nutritional status was significantly correlated with all general quality of life sub-scales. There was a statistically significant mean difference in change between groups for: symptoms of kidney disease (7.1 (0.1-14.1) p=0.047); cognitive functioning (14.6 (5.4-23.7) p=0.003); and vitality (12.0 (4.6-19.5) p=0.002) favouring intervention treatment.
  
  
  CONCLUSIONS
  Quality of life is related to nutritional status in pre-dialysis patients. Providing individualised nutritional counselling improves many components of quality of life, compared with standard nutrition care, in the stage prior to dialysis treatment.
authors.affiliation: Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Qld, Australia. katrina.campbell@kcl.ac.uk
authors.forename: Katrina Louise
authors.initials: KL
authors.lastname: Campbell
authors.forename: Susan
authors.initials: S
authors.lastname: Ash
authors.forename: Judith Dorothea
authors.initials: JD
authors.lastname: Bauer
mesh_terms: D000368:Aged; D018450:Disease Progression; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007676:Kidney Failure, Chronic / Q000178:diet therapy* / Q000523:psychology*; D008297:Male; D015596:Nutrition Assessment; D009752:Nutritional Status; D011788:Quality of Life; D016896:Treatment Outcome