Submicromolar, selective G-quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines.
Cetinkol
Ozgül Persil
OP
School of Chemistry and Biochemistry, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.
Engelhart
Aaron E
AE
Nanjunda
Rupesh K
RK
Wilson
W David
WD
Hud
Nicholas V
NV
D000818:Animals; D001372:Aza Compounds / Q000737:chemistry / Q000378:metabolism*; D001483:Base Sequence; D002417:Cattle; D004247:DNA / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D054856:G-Quadruplexes; D006801:Humans; D008024:Ligands; D013050:Spectrometry, Fluorescence; D013379:Substrate Specificity; D016615:Telomere / Q000235:genetics*; D013816:Thermodynamics
D001372:Aza Compounds; D008024:Ligands; D004247:DNA