Management of dyslipidaemia - evidence and practical recommendations.
BACKGROUND
Dyslipidaemia is a common condition managed in general practice.


OBJECTIVE
This article reviews the evidence and gives practical advice for the management of dyslipidaemia in general practice.


CONCLUSIONS
It is essential to identify people at risk of cardiovascular disease (CVD) and to instigate appropriate treatment strategies. An assessment of absolute risk is the most appropriate method of identifying those at a higher risk of CVD where CVD is not overt. People with an absolute risk of >15% of a cardiovascular event in the next 5 years should be actively treated. Drug therapy should also be considered in those estimated to be at 10-15% risk of a cardiovascular event in the next 5 years if they have additional risk factors. It is important to select an appropriate lipid lowering therapy (or combination of drugs) in order to reach lipid targets, which need to consider not just LDL-c but also HDL-c and triglycerides. Lifestyle management should underpin all lipid management strategies.
Nestel
Paul J
PJ
Cardiovascular Nutrition Laboratory, Baker Heart Research Institute, Melbourne, Victoria.
O'Brien
Richard
R
Nelson
Mark
M
D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D050171:Dyslipidemias / Q000150:complications / Q000628:therapy*; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008019:Life Style; D017063:Outcome Assessment, Health Care; D017410:Practice Guidelines as Topic; D012307:Risk Factors
D000960:Hypolipidemic Agents