Synthesis of quinolines from 3-formylchromone.
A facile and versatile procedure for the synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones was elaborated on the basis of TMSCl-mediated recyclization of 3-formylchromone with various anilines. Limitations and scope of this methodology were established, and a possible mechanism for the heterocyclizations was proposed.
Plaskon
Andrey S
AS
Enamine Ltd., 23 A. Matrosova st., Kyiv 01103, Ukraine.
Ryabukhin
Sergey V
SV
Volochnyuk
Dmitriy M
DM
Gavrilenko
Konstantin S
KS
Shivanyuk
Alexander N
AN
Tolmachev
Andrey A
AA
D002867:Chromones / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
D002867:Chromones; D011804:Quinolines; C502480:formylchromone