Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target.
The Japan Atherosclerosis Society (JAS) guidelines for the prevention of atherosclerotic diseases, proposing management for LDL cholesterol as the primary target, have successfully contributed to the prevention of cardiovascular events; however, recently, the impact of hypertriglyceridemia as an additional cardiovascular risk has become understood, especially in light of the rise in obesity, metabolic syndrome, and diabetes in the Japanese population. Rather than waiting to obtain conclusive domestic data confirming that hypertriglyceridemia is a cardiovascular risk factor and that its management is efficacious, we propose guidelines for hypertriglyceridemia using non-HDL cholesterol as a second target.
Shimano
Hitoshi
H
The Research Committee for Primary Hyperlipidemia, Research on Measures for Intractable Diseases by the Ministry for Health, Labor, and Welfare in Japan. shimano-tky@umin.ac.jp
Arai
Hidenori
H
Harada-Shiba
Mariko
M
Ueshima
Hirotsugu
H
Ohta
Takao
T
Yamashita
Shizuya
S
Gotoda
Takanari
T
Kiyohara
Yutaka
Y
Hayashi
Toshio
T
Kobayashi
Junji
J
Shimamoto
Kazuaki
K
Bujo
Hideaki
H
Ishibashi
Shun
S
Shirai
Koji
K
Oikawa
Shinichi
S
Saito
Yasushi
Y
Yamada
Nobuhiro
N
D050197:Atherosclerosis / Q000517:prevention & control; D015415:Biomarkers / Q000378:metabolism; D002309:Cardiology / Q000592:standards*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000473:pathology; D002784:Cholesterol / Q000378:metabolism; D008076:Cholesterol, HDL / Q000378:metabolism; D008078:Cholesterol, LDL / Q000378:metabolism*; D050171:Dyslipidemias / Q000175:diagnosis / Q000517:prevention & control; D017408:Guidelines as Topic; D006801:Humans; D015228:Hypertriglyceridemia / Q000517:prevention & control* / Q000628:therapy*; D007564:Japan; D008055:Lipids / Q000737:chemistry; D012307:Risk Factors
D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D002784:Cholesterol