Ongoing control of Haemophilus influenzae type B infections in Canadian children, 2004-2007.
The uniform use in Canada of a single Haemophilus influenzae type b conjugate vaccine in combination with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccines (DTaP.IPV/Hib) facilitates ongoing assessment of vaccine effectiveness, including any effects of recently added concurrent vaccinations and increasing time since vaccination. Surveillance at 12 pediatric centers in 2004-2007 indicates that vaccine failures remain rare and case totals approach an irreducible minimum, with no age shift.
Scheifele
David W
DW
Division of Pediatric Infectious and Immunologic Diseases, University of British Columbia, Vancouver, British Columbia. dscheifele@cw.bc.ca
Bettinger
Julie A
JA
Halperin
Scott A
SA
Law
Barbara
B
Bortolussi
Robert
R
D000293:Adolescent; D016667:Bacterial Capsules / Q000008:administration & dosage* / Q000276:immunology; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000008:administration & dosage* / Q000276:immunology; D006192:Haemophilus Infections / Q000453:epidemiology / Q000517:prevention & control*; D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000276:immunology; D019741:Haemophilus influenzae type b / Q000276:immunology*; D006801:Humans; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage* / Q000276:immunology; D016896:Treatment Outcome; D017778:Vaccines, Combined / Q000008:administration & dosage* / Q000276:immunology
D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D011054:Poliovirus Vaccine, Inactivated; D017778:Vaccines, Combined