Concise, Biomimetic Total Synthesis of d,l-Marcfortine C.
A biomimetic total synthesis of the fungal metabolite marcfortine C utilizing an intramolecular Diels-Alder reaction is described. In addition, a key stereoselective oxaziridine-mediated oxidation/pinacol rearrangement of indole 24 was used to complete the total synthesis.
Greshock
Thomas J
TJ
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523.
Grubbs
Alan W
AW
Williams
Robert M
RM