[Factors associated with microalbuminuria in non-hypertensive type-2 diabetes patients].
BACKGROUND
Microalbuminuria is a well known risk factor for renal damage and for cardiovascular disease in type-2 diabetic patients.


OBJECTIVE
To evaluate anthropometric, laboratory, and diet factors related to the presence of microalbuminuria in non-hypertensive type 2 diabetic subjects.


METHODS
We carry-out an assessment of a group of non-hypertensive diabetic patients with or without microalbuminuria. Some anthropometric measures, physical fitness, tobacco and alcohol consumption, creatinine clearance, HbA1c, lipid profile, the mean fast serum glucose levels in last two years, 24 h urine protein, and caloric intake were all measured.


RESULTS
From 86 included patients, 19 had microalbuminuria; it was related with the length of diabetes mellitus duration (114 +/- 55 vs. 84 +/- 67 months; p = 0.03), higher HbA1c level (8.9 vs. 7.1%; p = 0.001), and lower HDL-cholesterol levels (37.7 +/- 11 vs. 42.9 +/- 12 mg/dL; p = 0.03). In the multivariate analysis HbA1c level, and mean fast glucose remained significant.


CONCLUSIONS
In non-hypertensive diabetic subjects, poor glucose control, and longer disease duration were both related with microalbuminuria. Moreover, caloric intake, exercise, tobacco or alcohol consumption, or BMI did not show association with microalbuminuria.
López-Arce
Gustavo
G
Servicio de Medicina Interna, Hospital Central Sur de PEMEX. glopezarce@hotmail.com
Espinoza-Peralta
Diego
D
Hernández-Alarcón
Adriana
A
Arce-Salinas
C Alejandro
CA
D000419:Albuminuria / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged