Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography.
OBJECTIVE
To compare the efficacy of oral naproxen with intrauterine instillation of 1% lignocaine for pain relief in women undergoing hysterosalpingography (HSG) as an infertility investigation.


METHODS
One hundred women undergoing HSG were randomly allocated into 2 groups. Group A (n = 50) underwent intrauterine instillation of 5 mL of 1% lignocaine 2 minutes prior to the procedure, while the women in group B (n = 50) were instructed to self-administer a single oral dose of 375 mg of naproxen 1 hour prior to HSG. Pain scores immediately after the procedure (0 minutes) and delayed pain scores (30 minutes) were recorded and compared.


RESULTS
Women in both groups were comparable in age and parity. The mean +/- SD pain scores in group A and group B at 0 minutes and 30 minutes were not significantly different (P = 0.12 and P = 0.07).


CONCLUSIONS
Intrauterine lignocaine was no more effective than oral naproxen for pain relief during HSG.
Gupta
Nupur
N
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Ghosh
Bhaswati
B
Mittal
Suneeta
S
D000284:Administration, Oral; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000009:adverse effects*; D008012:Lidocaine / Q000008:administration & dosage*; D009288:Naproxen / Q000008:administration & dosage*; D010146:Pain / Q000517:prevention & control*; D014599:Uterus / Q000187:drug effects
D000700:Analgesics; D000779:Anesthetics, Local; D009288:Naproxen; D008012:Lidocaine