Synthesis of 3-selena-1-dethiacephems and selenazepines via iodocyclization.
A convenient approach to synthesize novel selenium-beta-lactams, 3-selena-1-dethiacephems and selenazepines, was accomplished via the regioselective iodocyclization reaction. The substituent of allenyl moieties dramatically influenced the regiochemical outcome in the iodocyclization of allene-selenourea derivatives.
Garud
Dinesh R
DR
Department of Chemistry, Faculty of Engineering, Gifu University, Gifu-501-1193, Japan.
Koketsu
Mamoru
M
D000480:Alkynes / Q000737:chemistry; D001381:Azepines / Q000138:chemical synthesis*; D002511:Cephalosporins / Q000138:chemical synthesis*; D003500:Cyclization; D007455:Iodine / Q000737:chemistry; D016566:Organoselenium Compounds / Q000138:chemical synthesis*; D047090:beta-Lactams / Q000138:chemical synthesis
D000480:Alkynes; D001381:Azepines; D002511:Cephalosporins; D016566:Organoselenium Compounds; D047090:beta-Lactams; D007455:Iodine