Contemporary practice patterns and beliefs regarding tocolysis among u.s. Maternal-fetal medicine specialists.
OBJECTIVE
To estimate maternal-fetal medicine specialists' practice patterns and perceived risks and benefits to tocolysis.


METHODS
We performed a mail-based survey of all Society for Maternal-Fetal Medicine (SMFM) members in the United States. Subjects were asked whether they would recommend tocolysis and what would be their first-line tocolytic in five scenarios: 1) acute preterm labor; 2) maintenance tocolysis after arrested preterm labor; 3) repeat acute preterm labor; 4) preterm premature rupture of membranes (PROM) without contractions; and 5) preterm PROM with contractions.


RESULTS
A total of 827 (46%) SMFM members responded. Ninety-six percent, 56%, 56%, 32%, and 29% would recommend tocolysis for acute preterm labor, repeat acute preterm labor, preterm PROM with contractions, preterm PROM without contractions, and maintenance tocolysis, respectively. The most common first-line tocolytic was magnesium for acute preterm labor (45%) and repeat acute preterm labor (41%); nifedipine was the most common maintenance tocolysis (79%). Eighty percent believed tocolysis was associated with moderate or significant benefit in the setting of acute preterm labor; however, fewer than 50% responded similarly for the other four scenarios. In all five scenarios, more than 50% of respondents indicated there was minimal or no risk associated with tocolysis. Having a nonacademic practice was independently associated with the recommendation for tocolysis.


CONCLUSIONS
Almost all maternal-fetal medicine specialists recommend tocolysis in the setting of acute preterm labor, and many recommend tocolysis for other indications. Magnesium and nifedipine are the most commonly prescribed first-line tocolytics.


METHODS
III.
Fox
Nathan S
NS
Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY, USA. naf9015@med.cornell.edu
Gelber
Shari E
SE
Kalish
Robin B
RB
Chasen
Stephen T
ST
D000328:Adult; D001291:Attitude of Health Personnel; D002983:Clinical Competence; D003625:Data Collection; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D009774:Obstetrics; D011177:Postal Service; D010818:Practice Patterns, Physicians'; D011247:Pregnancy; D047928:Premature Birth / Q000517:prevention & control*; D011295:Prenatal Care / Q000379:methods / Q000592:standards; D015145:Tocolysis / Q000706:statistics & numerical data*; D014481:United States