title: Evaluation of the palatability of three nonsteroidal antiinflammatory top-dress formulations in horses.
abstract: The efficacy of top-dress antiinflammatory drugs ultimately depends on a patient's willingness to consume treated feed. The current study compares the palatability of two phenylbutazone top-dress formulations (Equipalazone Powder, Dechra Pharmaceuticals, and Pro-Dynam, VetXX, Ltd.) and a suxibuzone top-dress formulation (Danilon Equidos, Janssen Animal Health). Results of a three-period, crossover study on 18 healthy horses showed that Pro-Dynam was significantly less palatable, with significantly less consumption of treated feed compared with either Equipalazone Powder or Danilon Equidos. There was no statistically significant difference in terms of consumption of treated feed and palatability scores between Equipalazone Powder and Danilon Equidos.
authors.affiliation: Dechra Pharmaceuticals PLC, Battlefield Enterprise Park, Shrewsbury, Shropshire, UK. susan.longhofer@dechra.com
authors.forename: Susan L
authors.initials: SL
authors.lastname: Longhofer
authors.forename: Craig R
authors.initials: CR
authors.lastname: Reinemeyer
authors.forename: Steven V
authors.initials: SV
authors.lastname: Radecki
mesh_terms: D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D018592:Cross-Over Studies; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D008297:Male; D010653:Phenylbutazone / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D013649:Taste / Q000502:physiology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; C003371:suxibuzone; D010653:Phenylbutazone