title: Cardiac cine MRI: Quantification of the relationship between fast gradient echo and steady-state free precession for determination of myocardial mass and volumes.
abstract: OBJECTIVE
  To determine the correlation function between the steady-state free precession (SSFP) and fast gradient echo (FGRE) cine MRI pulse sequences for measuring the myocardial mass and volumes.
  
  
  METHODS
  Cardiac cine MRI examinations were acquired in 50 individuals (female: 35, male: 15, mean age 64.1 +/- 9.1 years, range 48-83) using SSFP and FGRE cardiac pulse sequences.
  
  
  RESULTS
  The mean (standard deviation [SD]) left ventricular end diastolic volume measured by SSFP was significantly larger (4.5%) than by FGRE (P < 0.001); this was also the case for end systolic volume (15.0%, P < 0.001). The relationship between SSFP and FGRE measures were linear and highly correlated (P < 0.001) for both left ventricular end diastolic and end systolic volumes (r(2) = 0.90 vs. 0.91, respectively). We determined linear regression models to estimate the SSFP values based on the FGRE measures. Slope (intercept) for ejection fraction, stroke volume, and cardiac output were 0.99 (-2.79), 0.77 (17.5), and 0.76 (1.29), respectively.
  
  
  CONCLUSIONS
  Linear relationships exist for key LV function parameters when comparing SSFP and FGRE cine MRI. These results indicate that existing databases and normal values for FGRE LV function may be converted to corresponding LV function values for SSFP MRI.
authors.affiliation: Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA.
authors.forename: Ashkan Akhavan
authors.initials: AA
authors.lastname: Malayeri
authors.forename: W Craig
authors.initials: WC
authors.lastname: Johnson
authors.forename: Robson
authors.initials: R
authors.lastname: Macedo
authors.forename: Joan
authors.initials: J
authors.lastname: Bathon
authors.forename: João A C
authors.initials: JA
authors.lastname: Lima
authors.forename: David A
authors.initials: DA
authors.lastname: Bluemke
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002302:Cardiac Output / Q000502:physiology; D003971:Diastole / Q000502:physiology; D005260:Female; D006321:Heart / Q000033:anatomy & histology*; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000502:physiology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*