title: Contribution of serum biomarkers to the diagnosis of invasive candidiasis.
abstract: Invasive candidiasis is the most important opportunistic fungal infection, causing high morbidity and mortality. Traditional methods of diagnosis, which include blood culture and biopsy, usually lack both sensitivity and specificity, or become positive late in the course of the infection. Therefore, new nonculture-based methods are being developed. In this review, we will discuss the most recent studies concerning the use of serum biomarkers in the diagnosis of invasive Candida infections.
authors.affiliation: Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apartado 699, E-48080 Bilbao, Vizcaya, Spain. alain@cicbiogune.es
authors.forename: Ana
authors.initials: A
authors.lastname: Laín
authors.forename: Natalia
authors.initials: N
authors.lastname: Elguezabal
authors.forename: María Dolores
authors.initials: MD
authors.lastname: Moragues
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Ruiz
authors.forename: Amalia
authors.initials: A
authors.lastname: del Palacio
authors.forename: José
authors.initials: J
authors.lastname: Pontón
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood*; D002175:Candida; D002177:Candidiasis / Q000097:blood* / Q000175:diagnosis / Q000382:microbiology; D015169:Colony Count, Microbial / Q000379:methods; D006801:Humans; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers