pH and salivary sodium bicarbonate in cancer patients: correlation with seric concentration.
OBJECTIVE
To determine the correlation between pH and bicarbonate of soda in blood and saliva in child and adolescent patients during the administration of 3 g/m2 of methotrexate.


METHODS
A controlled clinical test was performed on 23 patients diagnosed with Acute Lymphoblastic Leukemia. Ages ranged from 4 to 18. The Spearman Correlation Coefficient was used to interpret the data.


RESULTS
No significant correlation was found between pH levels and seric and salivary sodium bicarbonate. However, there was a significant correlation between the levels of sodium bicarbonate in the body fluids evaluated (rs 0.2576, p=0.0354).


CONCLUSIONS
Changes modifying the microenvironment of the oral cavity probably do not allow saliva to be used to determine blood pH and seric bicarbonate.
Rojas-Morales
Thais
T
Research Institute, Faculty of Dentistry, Universidad del Zulia, Maracaibo, Zulia, Venezuela. moralesrojas@cantv.net
Navas
Rita
R
Viera
Ninoska
N
Alvarez
Carmen Julia
CJ
Chaparro
Neira
N
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006863:Hydrogen-Ion Concentration; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000378:metabolism*; D012463:Saliva / Q000737:chemistry*; D017693:Sodium Bicarbonate / Q000032:analysis* / Q000097:blood
D017693:Sodium Bicarbonate