Acute interstitial pneumonia in siblings: a case report.
Acute interstitial pneumonia (AIP) is a rapidly progressive condition of unknown cause that occurs in a previously healthy individual and produces the histologic findings of diffuse alveolar damage. Since the term AIP was first introduced in 1986, there have been very few case reports of AIP in children. Here we present a case of AIP in a 3-yr-old girl whose other two siblings showed similar radiologic findings. The patient was confirmed to have AIP from autopsy showing histological findings of diffuse alveolar damage and proliferation of fibroblasts. Her 3-yr-old brother was also clinically and radiologically highly suspected as having AIP, and the other asymptomatic 8-yr-old sister was radiologically suspected as having AIP.
Kwon
Seung Yeon
SY
Department of Pediatrics and Institution of Allergy, Yonsei University College of Medicine, Seoul, Korea.
Kim
Jong Min
JM
Sohn
Myung Hyun
MH
Kim
Dong Soo
DS
Kim
Myung Joon
MJ
Cho
Sang-Ho
SH
D000208:Acute Disease; D002675:Child, Preschool; D005192:Family Health; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000473:pathology; D035781:Siblings; D014057:Tomography, X-Ray Computed