Biomagnetic activity in prostate cancer and BPH.
OBJECTIVE
The aim of this study was to investigate the role of biomagnetic activity measurements in detecting prostate malignancies, in differentiating cancerous from benign prostate lesions and in generally improving our understanding of prostate cancer biology.


METHODS
Magnetic recordings were obtained from 47 patients with palpable prostate lesions. Twenty-four had prostate carcinoma and 23 benign prostatic hyperplasia (BPH).


RESULTS
The magnetic field recorded in the 2-7 Hz frequency range was of high amplitude in most (95%) malignant lesions 248 +/- 82 Ft/Hz) and of low amplitude in most (95%) benign ones (166 +/-31 Ft/Hz). These findings displayed significant difference (p = 0.0021).


CONCLUSIONS
Prostate cancer emits higher biomagnetic activity than BPH. This finding confirms the higher angiogenic activity of prostate cancer. The use of this method is safe and seems promising.
Anninos
P
P
Lab of Medical Physics, Medical School, Democritus University of Thrace, Alex/polis, Greece. anninosf@axd.forthnet.gr
Papadopoulos
I
I
Kotini
A
A
D000368:Aged; D004574:Electromagnetic Fields; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology
D017430:Prostate-Specific Antigen