Intrahepatic extramedullary hematopoiesis mimicking a hypervascular hepatic neoplasm on dynamic- and SPIO-enhanced MRI.
We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic MR imaging. The lesion did not demonstrate an apparent signal drop on a T2-weighted sequence following administration of a superparamagnetic iron-oxide agent (SHU 555A). A hepatocellular adenoma was the initial radiological diagnosis. To the best of our knowledge, this is the first report of a histopathologically proven intrahepatic EMH evaluated with dynamic- and SPIO-enhanced MRI.
Lee
In Joon
IJ
Department of Radiology, Seoul National University Hospital, Seoul, Korea.
Kim
Se Hyung
SH
Kim
Dae Sik
DS
Lee
Jeong Min
JM
Han
Joon Koo
JK
Choi
Byung Ihn
BI
D000236:Adenoma / Q000175:diagnosis*; D000328:Adult; D003937:Diagnosis, Differential; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008099:Liver / Q000502:physiology*; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D055728:Primary Myelofibrosis / Q000503:physiopathology