Efficacy of vaginal misoprostol before hysteroscopy for cervical priming in patients who have undergone cesarean section and no vaginal deliveries.
We wanted to investigate the effect of misoprostol administered vaginally before operative hysteroscopy on cervical dilation, complications, and failure rates in patients who have undergone cesarean section and who have never delivered vaginally. Sixty patients who had undergone cesarean section, who had never delivered vaginally before, and were about to undergo hysteroscopy for various intrauterine lesions were included in this randomized controlled study. Thirty-two patients in the study group were given misoprostol 400 microg, and 28 patients in the control group were given placebo (hexetidine pill) vaginally twice, 6 and 12 hours before the procedure. Primary endpoints were cervical width detected with Hegar dilators and complication and failure rates. Mean cervical width was greater in patients in the study group (6.5 +/- 0.8) than it was in patients in the control group (3.0 +/- 0.6), (p = .0001). Complication and failure rates were lower in patients in the study group (p = .01). Administration of vaginal misoprostol before hysteroscopy proved to be effective in cervical ripening and in reducing complication and failure rates.
Uckuyu
Ayla
A
Department of Obstetric and Gynecology, Baskent University Faculty of Medicine, Ankara, Turkey. aylauckuyu@yahoo.com
Ozcimen
Emel Ebru
EE
Sevinc
Faika Ceylan
FC
Zeyneloglu
Hulusi Bulent
HB
D000282:Administration, Intravaginal; D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects*; D002585:Cesarean Section; D036861:Delivery, Obstetric; D004106:Dilatation / Q000379:methods; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D016595:Misoprostol / Q000008:administration & dosage*; D011300:Preoperative Care; D014591:Uterine Diseases / Q000601:surgery
D016595:Misoprostol