title: Acute dystonia in a young schizophrenic patient associated with ingestion of a cloperastine containing cough syrup.
abstract: Acute dystonic reactions are usually observed after exposure to drugs with antidopaminergic actions. We report on one patient with acute dystonia associated with ingestion of a cloperastine containing syrup, who suffered from schizophrenia but had been neuroleptic-free for 6months. Cloperastine has antihistaminic properties. We suggest that antihistaminic agents may induce acute dystonia by altering the balance between dopamine and acetylcholine in the striatum.
authors.affiliation: Centro de Neurologia y Neurocirugia Funcional, Clinica Quirón, Parque Alcolea s/n, 20012 San Sebastián, Guipúzcoa, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Linazasoro
authors.forename: M T
authors.initials: MT
authors.lastname: Garmendia
authors.forename: X
authors.initials: X
authors.lastname: Lizaso