title: Investigation of Mycobacterium tuberculosis transmission aboard the U.S.S. Ronald Reagan, 2006.
abstract: Pulmonary tuberculosis (TB) was diagnosed in a sailor aboard the U.S.S. Ronald Reagan; an investigation was conducted to determine a screening strategy for 1,172 civilian passengers who were aboard during a temporary guest rider program. Sailors were screened for latent TB infection (LTBI) and TB disease. A case-control study was conducted among sailors to determine factors associated with new LTBI. No secondary TB disease was identified; 13% of close contacts had new LTBI. Factors associated with new LTBI among sailors were having been born outside the United States (adjusted odds ratio = 2.80; 95% confidence interval, 1.55--5.07) and being a carrier air wing member (adjusted odds ratio = 2.89; 95% confidence interval, 1.83--4.58). Among 38 civilian passengers berthed near the patient, 1 (3%) had LTBI. The investigation results indicated that Mycobacterium tuberculosis transmission was minimal and eliminated unnecessary TB screening for 1,134 civilians which saved public health resources.
authors.affiliation: Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, MS E-92, Atlanta, GA 30333, USA.
authors.forename: Ann M
authors.initials: AM
authors.lastname: Buff
authors.forename: Swati J
authors.initials: SJ
authors.lastname: Deshpande
authors.forename: Theresa A
authors.initials: TA
authors.lastname: Harrington
authors.forename: Taylor S
authors.initials: TS
authors.lastname: Wofford
authors.forename: Timothy W
authors.initials: TW
authors.lastname: O'Hara
authors.forename: Kenichi
authors.initials: K
authors.lastname: Carrigan
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Martin
authors.forename: Jackie C
authors.initials: JC
authors.lastname: McDowell
authors.forename: Kashef
authors.initials: K
authors.lastname: Ijaz
authors.forename: Paul A
authors.initials: PA
authors.lastname: Jensen
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Lambert
authors.forename: Marisa
authors.initials: M
authors.lastname: Moore
authors.forename: John E
authors.initials: JE
authors.lastname: Oeltmann
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D018562:Disease Transmission, Infectious; D006801:Humans; D008297:Male; D008403:Mass Screening; D008499:Medical Records; D008875:Middle Aged; D008889:Military Personnel / Q000706:statistics & numerical data*; D012306:Risk; D012767:Ships / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000635:transmission*; D014481:United States / Q000453:epidemiology