title: Brunner's gland hyperplasia: treatment of severe diffuse nodular hyperplasia mimicking a malignancy on pancreatic-duodenal area.
abstract: Brunner's gland hyperplasia is a benign tumor of the duodenum and it is rarely associated with clinical symptoms. We report on a 64-yr-old man with Brunner's gland hyperplasia who had undergone a duodenocephalo-pancreatectomy. The reason is that he presented upper gastrointestinal obstructive symptoms and the esophagogastroduodenoscopic finding revealed the lesion to be an infiltrating type mass on the second portion of the duodenum with luminal narrowing. An abdominal computed tomography showed a 2.5 cm-sized mass in the duodenal second portion with a suspicious pancreatic invasion and 7 mm-sized lymph node around the duodenum. Duodenocephalopancreatectomy was successfully performed. Histological examination revealed a Brunner's gland hyperplasia. The final diagnosis was the coexistence of Brunner's gland hyperplasia and pancreatic heterotopia with a pancreatic head invasion. The literature on Brunner's gland hyperplasia is reviewed.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Woong Chul
authors.initials: WC
authors.lastname: Lee
authors.forename: Hyeon Woong
authors.initials: HW
authors.lastname: Yang
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Lee
authors.forename: Sung Hee
authors.initials: SH
authors.lastname: Jung
authors.forename: Gi Young
authors.initials: GY
authors.lastname: Choi
authors.forename: Hoon
authors.initials: H
authors.lastname: Go
authors.forename: Anna
authors.initials: A
authors.lastname: Kim
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Cha
mesh_terms: D002011:Brunner Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D002828:Choristoma; D003937:Diagnosis, Differential; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D004386:Duodenum / Q000000981:diagnostic imaging / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D016577:Pancreaticoduodenectomy; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed