New qnr gene cassettes associated with superintegron repeats in Vibrio cholerae O1.
A novel qnr determinant emerged in ciprofloxacin-resistant Vibrio cholerae O1 from the Amazon region of Brazil. This qnrVC1 was in a typical class 1 integron. Its attC showed 89% identity with V. parahaemolyticus superintegron repeats. Analysis showed V. cholerae O1 carrying qnrVC2 associated with a V. cholerae superintegron repeat.
Fonseca
Erica L
EL
Instituto Oswaldo Cruz, Rio de Janeiro, Brazil; and Instituto Nacional de Controle de Qualidade em Saúde, Rio de Janeiro.
Dos Santos Freitas
Fernanda
F
Vieira
Verônica V
VV
Vicente
Ana C P
AC
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D002771:Cholera / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D006801:Humans; D032023:Integrons / Q000235:genetics; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D015363:Quinolones / Q000494:pharmacology; D017422:Sequence Analysis, DNA; D041241:Vibrio cholerae O1 / Q000187:drug effects / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015363:Quinolones