[Methodological aspects of evaluation of potential lipid capacity for peroxidation from the serum levels of TBA-active products during iron ion stimulation].
The authors propose a simple and reproducible procedure for using iron ions to stimulate serum lipid peroxidation, with TBA-active products being further determined. The procedure determines the reserve of lipids that can be oxidized during oxidative stress. A combination of direct studies and correlation analysis suggests that low-density lipoproteins and very low-density lipoproteins are the major substrates for lipid peroxidation while high-density lipoproteins show a high resistance to this process. The presented procedure may be used to monitor lipid peroxidation in various conditions and upon various exposures in common laboratory practice.
Kulikova
A I
AI
Tugusheva
F A
FA
Zubina
I M
IM
Shepilova
I N
IN
D001774:Blood Chemical Analysis; D007477:Ions / Q000097:blood / Q000737:chemistry; D007501:Iron / Q000097:blood* / Q000737:chemistry; D015227:Lipid Peroxidation; D008075:Lipoproteins, HDL / Q000097:blood / Q000737:chemistry; D008079:Lipoproteins, VLDL / Q000097:blood / Q000737:chemistry; D018384:Oxidative Stress; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis* / Q000737:chemistry
D007477:Ions; D008075:Lipoproteins, HDL; D008079:Lipoproteins, VLDL; D017392:Thiobarbituric Acid Reactive Substances; D007501:Iron