title: Clinical and histopathological analysis of oral squamous cell carcinoma in young people: a descriptive study in Brazilians.
abstract: We retrospectively analysed the clinical and histological characteristics of oral squamous cell carcinoma (SCC) in a sample of Brazilian patients 45 years of age or less. Files from a single oral histopathological service were studied during the period 1990 to 2005 and the clinical data collected. The histological sections of the invasive part of each tumour were analysed and classified using the criteria of Bryne et al. A total of 46 patients were selected, 36 (78%) of whom were white; 38 (83%) were male; and the most common site was the floor of the mouth (n=14, 30%) followed by the tongue (n=13, 28%). Most selected patients used tobacco and alcohol, and 43 were diagnosed as having clinical stages III and IV disease. Nine of the tumours (20%) were well differentiated, 23 were moderately differentiated, and the rest (n=14) were poorly differentiated. The characteristics of this group suggest that oral SCC in young patients does not behave differently from the oral SCC found in the overall population.
authors.affiliation: Department of Pathology and Clinical Propedeutics (Oral Pathology), São Paulo State University-UNESP, Araçatuba, São Paulo, Brazil. carol pr@yahoo.com.br
authors.forename: Ana Carolina Prado
authors.initials: AC
authors.lastname: Ribeiro
authors.forename: Alan Roger Santos
authors.initials: AR
authors.lastname: Silva
authors.forename: Luciana Estevam
authors.initials: LE
authors.lastname: Simonato
authors.forename: Leda Maria Pescinini
authors.initials: LM
authors.lastname: Salzedas
authors.forename: Maria Lucia Marçal Mazza
authors.initials: ML
authors.lastname: Sundefeld
authors.forename: Ana Maria Pires
authors.initials: AM
authors.lastname: Soubhia
mesh_terms: D000328:Adult; D000367:Age Factors; D001938:Brazil; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D009367:Neoplasm Staging; D012189:Retrospective Studies