title: Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography.
abstract: OBJECTIVE
  To compare the efficacy of oral naproxen with intrauterine instillation of 1% lignocaine for pain relief in women undergoing hysterosalpingography (HSG) as an infertility investigation.
  
  
  METHODS
  One hundred women undergoing HSG were randomly allocated into 2 groups. Group A (n = 50) underwent intrauterine instillation of 5 mL of 1% lignocaine 2 minutes prior to the procedure, while the women in group B (n = 50) were instructed to self-administer a single oral dose of 375 mg of naproxen 1 hour prior to HSG. Pain scores immediately after the procedure (0 minutes) and delayed pain scores (30 minutes) were recorded and compared.
  
  
  RESULTS
  Women in both groups were comparable in age and parity. The mean +/- SD pain scores in group A and group B at 0 minutes and 30 minutes were not significantly different (P = 0.12 and P = 0.07).
  
  
  CONCLUSIONS
  Intrauterine lignocaine was no more effective than oral naproxen for pain relief during HSG.
authors.affiliation: Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Nupur
authors.initials: N
authors.lastname: Gupta
authors.forename: Bhaswati
authors.initials: B
authors.lastname: Ghosh
authors.forename: Suneeta
authors.initials: S
authors.lastname: Mittal
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000009:adverse effects*; D008012:Lidocaine / Q000008:administration & dosage*; D009288:Naproxen / Q000008:administration & dosage*; D010146:Pain / Q000517:prevention & control*; D014599:Uterus / Q000187:drug effects
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D009288:Naproxen; D008012:Lidocaine