A case of CD45-negative diffuse large B-cell lymphoma in thyroid gland.
CD45, also referred to as the leukocyte common antigen (LCA), is selectively expressed on nucleated hematopoietic cells in healthy individuals. It is also widely expressed in various types of hematologic malignancies--although 10% of acute lymphoblastic leukemia and more than 50% of multiple myeloma have been reported to lack its expression. In this paper, we report a rare case of CD45-negative non-Hodgkin's lymphoma (NHL) that affected the thyroid gland.
Inaba
Tohru
T
Department of Infection Control and Laboratory Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan. inaba178@koto.kpu-m.ac.jp
Nishimura
Hiroshi
H
Saito
Junko
J
Yamane
Yoko
Y
Yuasa
Soichi
S
Hosokawa
Yohei
Y
Fujita
Naohisa
N
D000368:Aged; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D016130:Immunophenotyping; D017493:Leukocyte Common Antigens / Q000032:analysis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008297:Male; D013964:Thyroid Neoplasms / Q000473:pathology*
D017493:Leukocyte Common Antigens