Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease.
Mead
Adam J
AJ
Gale
Rosemary E
RE
Hills
Robert K
RK
Gupta
Manu
M
Young
Bryan D
BD
Burnett
Alan K
AK
Linch
David C
DC
D000483:Alleles; D015331:Cohort Studies; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000235:genetics*; D009154:Mutation; D011379:Prognosis; D011505:Protein-Tyrosine Kinases; D051941:fms-Like Tyrosine Kinase 3 / Q000235:genetics*
C497970:FLT3 protein, human; D011505:Protein-Tyrosine Kinases; D051941:fms-Like Tyrosine Kinase 3