title: Hypothalamic control of the pituitary-gonadal axis in higher primates: key advances over the last two decades.
abstract: This review provides a brief historical background to the foundation of primate reproductive neuroendocrinology that was laid by Ernst Knobil during the late 1960s and early 1970s. This is followed by a discussion of studies conducted over the last two decades that I view as having contributed to the current understanding of the field of primate reproductive neuroendocrinology. The review concludes with a short summary of key questions that remain to be addressed.
authors.affiliation: Department of Cell Biology and Physiology, University of Pittsburgh, Magee-Womens Research Institute, Pittsburgh, PA 15213, USA. plant1@pitt.edu
authors.forename: T M
authors.initials: TM
authors.lastname: Plant
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007031:Hypothalamus / Q000378:metabolism*; D020738:Leptin / Q000378:metabolism; D009452:Neuroendocrinology; D010913:Pituitary-Adrenal System / Q000502:physiology*; D011323:Primates; D011627:Puberty; D012098:Reproduction / Q000502:physiology
chemical_list: D020738:Leptin; D007987:Gonadotropin-Releasing Hormone