title: [Prepared evening primrose oil microspheres by spray drying].
abstract: OBJECTIVE
  To explore the best technique parameters on preparing evening primrose oil microspheres by spray drying technique.
  
  
  METHODS
  GC and internal standard method were used to determine the content of gamma-linolenic acid methyl esters, the technological parameters were investigated by orthogonal experimental design with the yield and entrapment rate as indexes.
  
  
  RESULTS
  The charging rate as 3 mL x min(-1), atomizing pressure as 100 kPa and the temperature of inlet as 105 degrees C were the best technique parameters.
  
  
  CONCLUSIONS
  Evening primrose oil microspheres accorded with the expecting demand. The main influencing factor is the charging rate. Spray drying is reasonable and practical for preparing evening primrose oil microspheres.
authors.affiliation: College of Pharmacy, Yanbian University, Yanji 133000, China. gjp807@ybu.edu.cn
authors.forename: Jian-Peng
authors.initials: JP
authors.lastname: Guo
authors.forename: Hong
authors.initials: H
authors.lastname: Xue
mesh_terms: D002849:Chromatography, Gas; D005240:Feasibility Studies; D016014:Linear Models; D008863:Microspheres; D031665:Oenothera biennis / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017965:gamma-Linolenic Acid / Q000032:analysis
chemical_list: D010938:Plant Oils; D017965:gamma-Linolenic Acid