title: Immunoglobulin A pemphigus associated with immunoglobulin A gammopathy and lung cancer.
abstract: Immunoglobulin (Ig)A pemphigus is a rare disease marked by a vesiculopustular eruption characterized by intercellular IgA deposition in the epidermis. It has clinical and histopathological heterogeneity and encompasses two subgroups: subcorneal pustular dermatosis type and intraepidermal neutrophilic IgA dermatosis type. IgA pemphigus has been rarely associated with monoclonal IgA paraprotein, myeloma and B-cell lymphoma in the past. We report the first case, to our knowledge, of a 47-year-old male patient with a subcorneal pustular dermatosis type of IgA pemphigus associated with IgA gammopathy and lung cancer.
authors.affiliation: Second Department of Dermatology and Venereology, A. Sygros Hospital, Athens, Greece.
authors.forename: Haritini
authors.initials: H
authors.lastname: Petropoulou
authors.forename: George
authors.initials: G
authors.lastname: Politis
authors.forename: Pantelis
authors.initials: P
authors.lastname: Panagakis
authors.forename: Eftihia
authors.initials: E
authors.lastname: Hatziolou
authors.forename: Kiriaki
authors.initials: K
authors.lastname: Aroni
authors.forename: George
authors.initials: G
authors.lastname: Kontochristopoulos
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D017809:Fatal Outcome; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008168:Lung / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D018307:Neoplasms, Squamous Cell / Q000150:complications* / Q000000981:diagnostic imaging; D010265:Paraproteinemias / Q000150:complications* / Q000276:immunology; D010392:Pemphigus / Q000150:complications* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D001323:Autoantibodies; D007070:Immunoglobulin A