title: Inhibition of Trichoderma reesei cellulase by sugars and solvents.
abstract: Inhibition of Trichoderma reesei cellulase by sugars (glucose, delta-gluconolactone, and cellobiose) and solvents (ethanol, butanol, and acetone) was studied using cellulose azure. Glucose, cellobiose, ethanol, and butanol were noncompetitive inhibitors, delta-gluconolactone was a mixed inhibitor, and acetone was a noncompetitive activator. Converting cellobiose to glucose reduces the effective inhibitor binding constant by 6 times and converting cellobiose to ethanol reduces it by 16 times.
authors.affiliation: Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, USA.
authors.forename: M
authors.initials: M
authors.lastname: Holtzapple
authors.forename: M
authors.initials: M
authors.lastname: Cognata
authors.forename: Y
authors.initials: Y
authors.lastname: Shu
authors.forename: C
authors.initials: C
authors.lastname: Hendrickson