title: [Postoperative manifestation of acute compartment syndrome by previously unknown heterozygote sickle cell anemia. A clinical case report].
abstract: Patients suffering from sickle cell disease show an increased ischemic intolerance due to continuous pro-inflammatory activation and dysfunction of the endothelium by recurrent vaso-occlusive episodes. The presented case shows the manifestation of a postoperative compartment syndrome of the lower leg following the intraoperative use of blood arrest in a patient with previously unknown sickle cell disease. Preexisting vulnerability for tissue hypoxia in patients at risk should be a major concern for intraoperative use of blood arrest during surgery of the extremities.
authors.affiliation: Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland. antje.schulz@charite.de
authors.forename: A
authors.initials: A
authors.lastname: Schulz
authors.forename: A C
authors.initials: AC
authors.lastname: Disch
authors.forename: I
authors.initials: I
authors.lastname: Melcher
authors.forename: N P
authors.initials: NP
authors.lastname: Haas
authors.forename: K-D
authors.initials: KD
authors.lastname: Schaser
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications* / Q000175:diagnosis / Q000235:genetics*; D000868:Anterior Compartment Syndrome / Q000175:diagnosis* / Q000601:surgery; D001859:Bone Neoplasms / Q000601:surgery*; D001860:Bone Plates; D002812:Chondroma / Q000175:diagnosis / Q000601:surgery*; D005500:Follow-Up Studies; D006580:Genetic Carrier Screening; D006451:Hemoglobin, Sickle / Q000235:genetics; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis* / Q000601:surgery; D012086:Reoperation; D013536:Suture Techniques; D013977:Tibia / Q000601:surgery*; D014945:Wound Healing; D055815:Young Adult
chemical_list: D006451:Hemoglobin, Sickle