title: Continent orthotopic ileal neobladder after kidney transplantation in a patient with urothelial cell carcinoma associated with Chinese herb nephropathy.
abstract: A 58-year-old man underwent kidney transplantation on November 14, 2002 for end-stage kidney disease after Chinese herb nephropathy. Immunosuppressive therapy was maintained with tacrolimus, mycophenolate mofetil, and methylpredonisolone. He was diagnosed with right ureteral cancer and underwent right nephroureterectomy on December 13, 2003. Then, he underwent left nephroureterectomy for left ureteral cancer on March 5, 2004. Subsequently, he was diagnosed with multiple bladder cancers and carcinoma in situ. On August 31, he underwent radical cystectomy with an orthotopic ileal neobladder (Studer's method). The postoperative course was uneventful. After 3 years follow-up, this patient shows no evidence of recurrence and his serum creatinine level is stable (1.7 mg/dL). The continence is maintained during both day and night; he voids without intermittent self-catheterization. We suggest that an orthotopic ileal neobladder is a safe method of urinary diversion after cystectomy in kidney transplant recipients.
authors.affiliation: Department of Urology, Tokyo Women's Medical University, Tokyo, Japan. hirokilolo@sepia.ocn.ne.jp
authors.forename: H
authors.initials: H
authors.lastname: Shirakawa
authors.forename: H
authors.initials: H
authors.lastname: Ishida
authors.forename: Y
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: K
authors.initials: K
authors.lastname: Omoto
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Setoguchi
authors.forename: S
authors.initials: S
authors.lastname: Iida
authors.forename: D
authors.initials: D
authors.lastname: Toki
authors.forename: K
authors.initials: K
authors.lastname: Tanabe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003404:Creatinine / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000633:toxicity*; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000139:chemically induced / Q000601:surgery; D007668:Kidney / Q000473:pathology*; D016030:Kidney Transplantation; D008297:Male; D009035:Mothers; D014019:Tissue Donors; D014513:Ureter / Q000601:surgery; D001743:Urinary Bladder / Q000503:physiopathology*; D014554:Urination
chemical_list: D004365:Drugs, Chinese Herbal; D003404:Creatinine