[Influence of Qingpeng plaster on blood vessels and mast cells in skin tissue of channel points of nude mice].
OBJECTIVE
To investigate the changes in the numbers of blood vessels and mast cells, which is relative to blood microcirculation in skin, during Qingpeng plaster (ZANG medicine) being applied to the skin surface of nude mice.


METHODS
Fifteen healthy adult nude mice were divided into Qingpeng plaster group and the control group. The sites of skin tissues stuck with the plaster or with control plaster were selected after 7 days treated, and then all the slices stained and observed.


RESULTS
The numbers of the vessels and the mast cells increased in the dermal tissue of Qingpeng paster group. Although there were a few dilated blood vessels in the control group, but the numbers of the vessels and the mast cells were obviously less than those of the Qingpeng plaster group. Statistical analysis showed that there was a significant difference (P < 0.001) between tow groups.


CONCLUSIONS
Qingpeng plaster can cause obvious vascular dilatation and promot mast cells aggregation in the Qingpeng plaster stuck parts of the skin tissue.
Luo
Ming-Fu
MF
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China. psy_1mf@yahoo.com.cn
Li
Cui-Hong
CH
Zhang
Dong
D
Guo
Ying
Y
He
Jun-Na
JN
Ma
Hui-Min
HM
Wang
Shu-You
SY
Li
Shun-Yue
SY
D000818:Animals; D001808:Blood Vessels / Q000166:cytology / Q000187:drug effects*; D002452:Cell Count; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000494:pharmacology*; D005260:Female; D008297:Male; D008407:Mast Cells / Q000166:cytology / Q000187:drug effects*; D051379:Mice; D008819:Mice, Nude; D012867:Skin / Q000098:blood supply / Q000166:cytology* / Q000187:drug effects*
D004365:Drugs, Chinese Herbal; C540321:Qingpeng plaster