title: [Type 1 diabetic patients evolution to hypertension].
abstract: OBJECTIVE
  Check the evolution of type 1(T1) diabetic patients to hypertension and prehypertension and baseline factors related to final blood pressure levels (BP).
  
  
  METHODS
  Observational study involving 127 T1 diabetic patients submitted to clinical and laboratory evaluation and followed by for 5 (2.4-9.2) years.
  
  
  RESULTS
  From the initially normotensive patients, 21.7% developed prehypertension, 4.7% developed hypertension and 73.6% remained with normal BP. From the prehypertensive patients, 35% returned to normal BP, 50% remained prehypertensive and 15% developed hypertension. The relative risk for hypertension development was 3.2 (0.8-12.3) in the prehypertensive compared to the normotensive group. The prevalence of prehypertension and hypertension increased from 15.7% to 26% and 0.8% to 7% respectively. Levels of serum creatinine predicted final levels of systolic and diastolic BP.
  
  
  CONCLUSIONS
  It is emphasized the importance of renal function and BP evaluation even when they are in normal range to minimize the deleterious effects of hypertension in the development of nephropathy and cardiovascular disease.
authors.affiliation: Faculdade de Ciências Médicas, Universidade Estadual do Rio de Janeiro, RJ, Brasil. robertacobas@ig.com.br
authors.forename: Roberta
authors.initials: R
authors.lastname: Cobas
authors.forename: Bráulio
authors.initials: B
authors.lastname: Santos
authors.forename: Luiza
authors.initials: L
authors.lastname: Braga
authors.forename: Edna Ferreira
authors.initials: EF
authors.lastname: Cunha
authors.forename: Marilia Brito
authors.initials: MB
authors.lastname: Gomes
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003404:Creatinine / Q000097:blood; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000209:etiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D008137:Longitudinal Studies; D008297:Male; D015995:Prevalence; D055815:Young Adult
chemical_list: D003404:Creatinine