Colorimetric discrimination between important alkaloid nuclei mediated by a bis-salphen chromophore.
A new colorimetric method is presented that allows for simple and effective discrimination between (iso)quinoline nuclei pertinent to many alkaloid species. The method is based on the reversible incorporation of Zn2+ ions into a bis-salphen chromophore under aqueous conditions. The metalation process is a function of the stability of the Zn-N (acceptor-donor) interaction and is accompanied by a clear colorimetric response.
Wezenberg
Sander J
SJ
Institute of Chemical Research of Catalonia (ICIQ), Av. Paisos Catalans 16, 43007 Tarragona, Spain.
Escudero-Adán
Eduardo C
EC
Benet-Buchholz
Jordi
J
Kleij
Arjan W
AW
D000470:Alkaloids / Q000737:chemistry*; D003124:Colorimetry / Q000379:methods*; D018360:Crystallography, X-Ray; D007546:Isoquinolines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013056:Spectrophotometry, Ultraviolet; D017967:Zinc Compounds / Q000737:chemistry*
D000470:Alkaloids; D007546:Isoquinolines; D017967:Zinc Compounds