title: Clinical outcome of diabetic foot ulcers treated with negative pressure wound therapy and the transition from acute care to home care.
abstract: Diabetic foot ulcers affect millions of people in the United States of America and impose tremendous medical, psychosocial and financial loss or burden. Negative pressure wound therapy (NPWT) is generally well tolerated and appears to stimulate a robust granulation tissue response compared with other wound healing modalities. This device may be a cost-effective adjunctive wound healing therapy. This literature review will focus on the clinical outcome of diabetic foot ulcers treated with NPWT, its implication in the transition from acute care to home care, factors that might influence clinical outcomes in home care as well as quality-of-life aspects in these patients. Patient care for diabetic foot ulceration is complex and necessitates multiprofessional collaboration to provide comprehensive wound care. It is clear that when we strive for limb preservation in this most high-risk population, it is important to have an available versatile, efficacious wound healing modality. There is a need for an easy transition from acute care to home care. Resources need to be combined in a collaborative and synergistic fashion to allow patient to perform many daily living activities while receiving the potential benefits of an advanced wound healing modality.
authors.affiliation: Department of Surgery, Dr William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Center for Lower Extremity Ambulatory Research, 3333 Green Bay Road, North Chicago, IL 60048, USA.
authors.forename: Stephanie C
authors.initials: SC
authors.lastname: Wu
authors.forename: David G
authors.initials: DG
authors.lastname: Armstrong
mesh_terms: D003266:Continuity of Patient Care / Q000458:organization & administration; D003299:Cooperative Behavior; D003362:Cost-Benefit Analysis; D017719:Diabetic Foot / Q000628:therapy*; D019317:Evidence-Based Medicine; D006699:Home Care Services / Q000458:organization & administration; D006801:Humans; D053208:Kaplan-Meier Estimate; D054843:Negative-Pressure Wound Therapy / Q000379:methods* / Q000451:nursing; D017063:Outcome Assessment, Health Care; D010348:Patient Care Team / Q000458:organization & administration; D010351:Patient Discharge; D018579:Patient Selection; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D012449:Safety; D014945:Wound Healing