title: Measurement and analysis of the flow field in a pulsatile ventricularassist device.
abstract: A pneumatically driven ventricular assist device (VAD) of unconventional geometry, designed to mitigate adverse haemostatic phenomena by optimization of flow patterns, was investigated using two-component laser Doppler anemometry (LDA). Data were taken on a rectilinear grid over two orthogonal traverses, allowing synthesis of three-dimensional velocity vectors over most of the grid. The resulting data were examined by two-dimensional and three-dimensional static and animated computer graphic visualizations of the time-varying vector fields. This analysis revealed illuminating and previously unobserved features of the complex flow fields within pulsatile VADs and identified design considerations that bear upon minimization of turbulence and of flow recirculation and stasis. The findings of this study suggest that, while total abolition of undesirable flow phenomena in a diaphragm-type blood pump is probably impossible, comprehensive investigation in vitro can engender considerable improvements in the efficacy of a device.
authors.affiliation: Graduate School of Biomedical Engineering, University of New South Wales, Sydney, New South Wales, Australia. Allen.nugent@unsw.edu.au
authors.forename: A H
authors.initials: AH
authors.lastname: Nugent
authors.forename: C D
authors.initials: CD
authors.lastname: Bertram
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D003198:Computer Simulation; D006353:Heart-Assist Devices; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology*; D016276:Ventricular Function