title: Low-pressure airlift fermenter for single cell protein production: II. Continuous culture of pichia yeast.
abstract: Experiments using Pichia yeast grown on n-paraffins have been conducted in laboratory 10-L airlift fermenters and in a 640-L module of commercial scale. Results confirmed the design concept of combining oxygen transfer and fermenter cooling with low-pressure air. However, in the absence of mass transport constraints, the build up of toxic factors in the fermenter appeared to be a major variable limiting cell productivity. Foaming in the large fermenter also presented a serious problem, which must be solved before low-pressure airlift fermenters become practical.
authors.affiliation: Mobil Research and Development Corporation, Central Research Laboratory, P.O. Box 1025, Princeton, NJ 08540.
authors.forename: N Y
authors.initials: NY
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Srinivasan
authors.forename: R I
authors.initials: RI
authors.lastname: Leavitt
authors.forename: V F
authors.initials: VF
authors.lastname: Coty
authors.forename: E F
authors.initials: EF
authors.lastname: Kondis