title: [Fatal ewe's milk-induced anaphylaxis: laboratory work-up].
abstract: Selective ewe's or goat's milk allergy without cow's milk allergy often presents as a severe picture. Diagnosis and follow-up are facilitated by the use of laboratory tests. Serum tryptase is elevated after mast cell degranulation. Combined determination of serum tryptase and immunoglobulin-E levels are particularly useful in the work-up of anaphylaxis, should it have been fatal. A case of ewe's milk allergy without cow's milk allergy and its laboratory work-up are reported.
authors.affiliation: Laboratoire d'immunologie, INSERM UMR 600/CNRS UMR 6212, hôpital de la Conception, Assistance publique-Hôpitaux de Marseille, faculté de médecine de Marseille, 147 boulevard Baille, Marseille, France. jvitte@ap-hm.fr
authors.forename: J
authors.initials: J
authors.lastname: Vitte
authors.forename: P
authors.initials: P
authors.lastname: Bongrand
mesh_terms: D000707:Anaphylaxis / Q000209:etiology* / Q000276:immunology / Q000401:mortality*; D000818:Animals; D001344:Autopsy; D002648:Child; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D016269:Milk Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000401:mortality*; D012756:Sheep; D053802:Tryptases / Q000032:analysis
chemical_list: D007073:Immunoglobulin E; D053802:Tryptases