title: [Quantitative changes of anti-cancer active components in Taxus chinensis var. mairei branches and leaves].
abstract: The quantitative changes of anti-cancer ingredients such as taxol, cephalomannine, baccatin III and 10-deacetylbaccatin III in the branches and leaves of Taxus chinensis var. mairei during one growth season were measured by HPLC. The results showed that the contents of these anticancer ingredients had an obvious change from April when the new branches began to germinate to November when the branches basically stopped growing. The contents of taxol and cephalomannine in the branches and leaves of T. chinensis had the same change pattern, with the peaks appeared in May, and those of Baccatin III and 10-deacetylbaccatin III had the same change trend, with the highest values appeared in September and April, respectively. There was a significant positive correlation between the contents of taxol and cephalomannine (P <0.05), and a negative correlation between the contents of cephalomannine and 10-deacetylbaccatin III (P <0.05).
authors.affiliation: Key Laboratory of Forest Plant Ecology of Education Ministry, Northeast Forestry University, Harbin 150040, China. yangfengjian2003@yahoo.com.cn
authors.forename: Feng-jian
authors.initials: FJ
authors.lastname: Yang
authors.forename: Hai-he
authors.initials: HH
authors.lastname: Pang
authors.forename: Xue-ke
authors.initials: XK
authors.lastname: Zhang
authors.forename: Jia-yin
authors.initials: JY
authors.lastname: Sun
authors.forename: Yuan-gang
authors.initials: YG
authors.lastname: Zu
mesh_terms: D000470:Alkaloids / Q000032:analysis; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D017239:Paclitaxel / Q000032:analysis; D018515:Plant Leaves / Q000737:chemistry* / Q000254:growth & development; D012621:Seasons; D043823:Taxoids / Q000032:analysis; D020946:Taxus / Q000737:chemistry* / Q000254:growth & development
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; C073950:baccatin III; C056348:cephalomannine; D017239:Paclitaxel