title: On-pump beating heart mitral valve surgery without cross-clamping the aorta.
abstract: OBJECTIVE
  Cardiac reperfusion injury is a well-described complication occurring after ischemia or following cardioplegic arrest. Various strategies have been developed to prevent ischemic reperfusion injury. The aim of this study was to assess the efficacy and applicability of the on-pump beating heart mitral valve surgery without cross-clamping the aorta in order to prevent reperfusion injury.
  
  
  METHODS
  The prospective study (between April 2005 and December 2006) included 88 consecutive patients who underwent mitral valve surgery. The operations were carried out on a beating heart using normothermic cardiopulmonary bypass without cross-clamping the aorta, therefore perfusing the heart antegradely through the aortic root. Venting the heart from the aorta and the pulmonary vein provided adequate visualization of the operative field.
  
  
  RESULTS
  Seventy-eight patients (88.6%) underwent mitral valve replacement and 10 patients (11.3%) underwent mitral valve repair with this technique. Concomitant surgery was required in 29 patients (32.9%). Twenty-five patients (28.4%) had also undergone previous open heart surgery. Mean cardiopulmonary bypass time was 57.4 +/- 18.4 minutes. Mean duration of ventilation was 12.2 +/- 3.5 hours, mean intensive care unit stay was 1.3 +/- 1.6 days, and mean hospital stay was 6.9 +/- 4.5 days. One-year survival was 96.6% for all causes of mortality.
  
  
  CONCLUSIONS
  In this study, we showed that on-pump beating heart operations without cross-clamping is an acceptable surgical choice for mitral valve disease. Complication rates are low and perioperative mortality is lower than that generally reported with conventional technique.
authors.affiliation: Cardiovascular Surgery Clinic, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey. fehmiege@yahoo.com
authors.forename: Salih Fehmi
authors.initials: SF
authors.lastname: Katircioglu
authors.forename: Ferit
authors.initials: F
authors.lastname: Cicekcioglu
authors.forename: Ufuk
authors.initials: U
authors.lastname: Tutun
authors.forename: Ali Ihsan
authors.initials: AI
authors.lastname: Parlar
authors.forename: Seyhan
authors.initials: S
authors.lastname: Babaroglu
authors.forename: Ufuk
authors.initials: U
authors.lastname: Mungan
authors.forename: Aysen
authors.initials: A
authors.lastname: Aksoyek
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001013:Aorta, Thoracic; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D003250:Constriction; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*