[Metabonomics in medical and pharmaceutical research].
Metabonomics is a new "-omics" science in post-gene time. Metabonomics can directly understand the physiological and biochemical situation by its "metabolome profile" as a whole, and therefore can provide various information that differs from other "-omics". Metabonomics has been applied in disease diagnosis, assessment of animal models, screening of new drugs, evaluation of drug safety, discovery of new bio-markers of toxicity, as well as research of traditional Chinese medicine.
Liu
Chang-Xiao
CX
Tianjin National Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China.
D000818:Animals; D054316:Biomarkers, Pharmacological / Q000378:metabolism; D035843:Biomedical Research; D003933:Diagnosis; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008516:Medicine, Chinese Traditional; D055442:Metabolome; D055432:Metabolomics; D023421:Models, Animal; D018675:Toxicity Tests
D054316:Biomarkers, Pharmacological