Vortex chamber for in situ recovery of the antibiotic Myxovirescin A in continuous cultivation.
A vortex chamber for continuous adsorption of the antibiotic Myxovirescin A on XAD resins was developed. In this paper the design and use of the vortex chamber in an external bypass of a continuous process is described. Compared with the normal continuous process, the specific production rate of the antibiotic is four to five times higher when the antibiotic is continuously adsorbed. A semicontinuous process could be performed by using two chambers for adsorption and regeneration alternatively.
Hecht
V
V
GBF-Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig-Stöckheim, Federal Republic of Germany.
Vorlop
J
J
Kalbitz
H
H
Gerth
K
K
Lehmann
J
J