title: Phylogenetic characterization of canine distemper virus isolates from naturally infected dogs and a marten in Korea.
abstract: We sequenced the hemagglutinin (H) genes from four canine distemper virus (CDV) isolates obtained from three dogs and a marten in Korea. These sequences were included in subsequent H gene-focused phylogenetic tree analysis of 89 CDV strains. This analysis revealed eight clades designated as EU1, EU2, EU3, NA1, NA2, Asia 1, Asia 2 and Vaccine. Three of the Korean isolates (97Jindo, 98Marten and 07D111) occurred in the Asia 2 group that also contains many Japanese CDV strains isolated in 1998. The remaining Korean strain (07Q72) fell into the Asia 1 group. The 21 H protein sequences of 25 Asia 1 strains are generally predicted to bear nine potential N-linked glycosylation sites. In contrast, the 9 H protein sequences of 12 Asia 2 strains had eight potential N-linked glycosylation sites. The remaining strains had six (98Marten and 07D111) and seven (97Jindo) potential N-linked glycosylation sites.
authors.affiliation: National Veterinary Research and Quarantine Service, Anyang, Kyunggi-do 430-824, Republic of Korea.
authors.forename: Dong-Jun
authors.initials: DJ
authors.lastname: An
authors.forename: Sook-Hee
authors.initials: SH
authors.lastname: Yoon
authors.forename: Jee-Yong
authors.initials: JY
authors.lastname: Park
authors.forename: In-Sun
authors.initials: IS
authors.lastname: No
authors.forename: Bong-Kyun
authors.initials: BK
authors.lastname: Park
mesh_terms: D000818:Animals; D004216:Distemper / Q000453:epidemiology / Q000821:virology*; D004217:Distemper Virus, Canine / Q000235:genetics*; D004285:Dogs; D005260:Female; D014644:Genetic Variation; D007723:Korea / Q000453:epidemiology; D008297:Male; D045969:Mustelidae / Q000821:virology*; D010802:Phylogeny