title: "Click chemistry" in zeolites: copper(I) zeolites as new heterogeneous and ligand-free catalysts for the Huisgen [3+2] cycloaddition.
abstract: For the first time, copper(I)-exchanged zeolites were developed as catalysts in organic synthesis. These solid materials proved to be versatile and efficient heterogeneous, ligand-free catalytic systems for the Huisgen [3+2] cycloaddition. These cheap and easy-to-prepare catalysts exhibited a wide scope and compatibility with functional groups. They are very simple to use, easy to remove (by filtration), and are recyclable (up to three times without loss of activity). Investigations with deuterated alkynes and deuterated zeolites proved that this Cu(I)-zeolite-catalyzed "click" reaction exhibited a mechanism different from that reported for the Meldal-Sharpless version.
authors.affiliation: Laboratoire de Physicochimie des Hydrocarbures, Institut de Chimie de Strasbourg, 4 rue Blaise Pascal, Strasbourg, France.
authors.forename: Stefan
authors.initials: S
authors.lastname: Chassaing
authors.forename: Abdelkarim
authors.initials: A
authors.lastname: Sani Souna Sido
authors.forename: Aurélien
authors.initials: A
authors.lastname: Alix
authors.forename: Mayilvasagam
authors.initials: M
authors.lastname: Kumarraja
authors.forename: Patrick
authors.initials: P
authors.lastname: Pale
authors.forename: Jean
authors.initials: J
authors.lastname: Sommer