title: Sex hormone effects on body fluid regulation.
abstract: In young women, estradiol and progesterone primarily control reproduction, but they also affect fluid regulation. Estradiol lowers the operating point for osmoregulation of arginine vasopressin and thirst and increases plasma volume. Although total body water and sodium content are only mildly affected, data presented in this article suggest that reproductive hormones alter homeostatic set points for body fluid and tonicity.
authors.affiliation: The John B. Pierce Laboratory and Yale University School of Medicine, New Haven, CT 06519, United States. nstach@jbpierce.org
authors.forename: Nina S
authors.initials: NS
authors.lastname: Stachenfeld
mesh_terms: D001127:Arginine Vasopressin / Q000187:drug effects; D001826:Body Fluids / Q000187:drug effects*; D004958:Estradiol / Q000502:physiology*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000037:antagonists & inhibitors; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D016729:Leuprolide / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D008297:Male; D011374:Progesterone / Q000502:physiology*; D012462:Saline Solution, Hypertonic; D012964:Sodium; D013894:Thirst; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D012462:Saline Solution, Hypertonic; D001127:Arginine Vasopressin; D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D004958:Estradiol; D012964:Sodium; D016729:Leuprolide; C061018:ganirelix