title: Achieving behavioral control with millisecond resolution in a high-level programming environment.
abstract: The creation of psychophysical tasks for the behavioral neurosciences has generally relied upon low-level software running on a limited range of hardware. Despite the availability of software that allows the coding of behavioral tasks in high-level programming environments, many researchers are still reluctant to trust the temporal accuracy and resolution of programs running in such environments, especially when they run atop non-real-time operating systems. Thus, the creation of behavioral paradigms has been slowed by the intricacy of the coding required and their dissemination across labs has been hampered by the various types of hardware needed. However, we demonstrate here that, when proper measures are taken to handle the various sources of temporal error, accuracy can be achieved at the 1 ms time-scale that is relevant for the alignment of behavioral and neural events.
authors.affiliation: Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, USA. wfasaad@alum.mit.edu
authors.forename: Wael F
authors.initials: WF
authors.lastname: Asaad
authors.forename: Emad N
authors.initials: EN
authors.lastname: Eskandar
mesh_terms: D000818:Animals; D001519:Behavior / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology*; D001525:Behavioral Sciences / Q000295:instrumentation / Q000379:methods*; D001921:Brain / Q000502:physiology; D006801:Humans; D008838:Microcomputers; D009482:Neurophysiology / Q000295:instrumentation / Q000379:methods; D011381:Programming Languages; D011589:Psychology, Experimental / Q000592:standards / Q000639:trends; D011601:Psychophysics / Q000295:instrumentation / Q000379:methods*; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D012984:Software / Q000592:standards / Q000639:trends*; D012985:Software Design; D012986:Software Validation; D013997:Time Factors; D014584:User-Computer Interface