title: Imaging of congenital diaphragmatic hernias.
abstract: Congenital diaphragmatic hernias are complex and life-threatening lesions that are not just anatomic defects of the diaphragm, but represent a complex set of physiologic derangements of the lung, the pulmonary vasculature, and related structures. Imaging plays an increasingly important role in the care of these infants. Prenatal sonography and MRI have allowed early and accurate identification of the defect and associated anomalies. These tools have also been the key to defining the degree of pulmonary hypoplasia and to predicting neonatal survival and need for aggressive respiratory rescue strategies. In the postnatal period, conventional radiography supplemented by cross-sectional imaging in selected cases can be very useful in sorting out the differential diagnosis of intrathoracic masses, in the detection of associated anomalies, and in the management of complications. Understanding the pathogenesis of diaphragmatic defects, the underlying physiologic disturbances, and the strengths and limitations of current imaging protocols is essential to the effective and accurate management of these complex patients.
authors.affiliation: Department of Radiology, Children's Hospital Boston, Harvard Medical School, 300 Longwood Ave., Boston, MA 02115, USA. george.taylor@childrens.harvard.edu
authors.forename: George A
authors.initials: GA
authors.lastname: Taylor
authors.forename: Omolola M
authors.initials: OM
authors.lastname: Atalabi
authors.forename: Judy A
authors.initials: JA
authors.lastname: Estroff
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D003964:Diaphragm / Q000002:abnormalities; D006548:Hernia, Diaphragmatic / Q000175:diagnosis* / Q000601:surgery; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011296:Prenatal Diagnosis