title: Adequacy of surgeon-performed ultrasound-guided thyroid fine-needle aspiration biopsy.
abstract: OBJECTIVE
  To determine the diagnostic accuracy of specimens obtained by a surgeon performing office-based ultrasound (US)-guided fine-needle aspiration biopsy (FNAB) of thyroid nodules.
  
  
  METHODS
  From 2003 to 2006, a single surgeon performed 447 consecutive office-based US-guided FNABs without on-site cytological specimen evaluation. Adequate specimens had at least six clusters of follicular cells from at least two separate needle passes.
  
  
  RESULTS
  Non-diagnostic specimens occurred in 16 of 447 (3.6%) nodules, whereas suboptimal specimens occurred in 17 of 447 (3.8%). Adequate samples were obtained in 413 of 447 (92.6%) of specimens. Malignancy was present in 20 of 447 (4.5%) and atypical features were present in 37 of 447 (8.3%). Benign diagnoses were rendered in 357 of 447 (79.9%) of specimens, of which four of 357 (1.1%) represented false-negative results.
  
  
  CONCLUSIONS
  Prior publications recommend that obtaining adequate thyroid cytology specimens requires use of US-guided FNAB and on-site evaluation of cytology adequacy. This study demonstrates that a combination of experienced US guidance, both capillary and aspiration sampling, and three to four needle passes produce comparable results while conserving costs and resources.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
authors.forename: Amol M
authors.initials: AM
authors.lastname: Bhatki
authors.forename: Brad
authors.initials: B
authors.lastname: Brewer
authors.forename: Toni
authors.initials: T
authors.lastname: Robinson-Smith
authors.forename: Yuri
authors.initials: Y
authors.lastname: Nikiforov
authors.forename: David L
authors.initials: DL
authors.lastname: Steward
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods* / Q000592:standards; D005260:Female; D013502:General Surgery; D006801:Humans; D008297:Male; D013964:Thyroid Neoplasms / Q000473:pathology; D016606:Thyroid Nodule / Q000000981:diagnostic imaging* / Q000473:pathology*; D014463:Ultrasonography