Maternal and fetal exposure to bisphenol A in Korea.
Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 microg/L in pregnant women and from non-detectable to 8.86 microg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p<0.05).
Lee
Young Joo
YJ
Human Exposure Assessment Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Republic of Korea.
Ryu
Heui-Young
HY
Kim
Hyun-Kyung
HK
Min
Chung Sik
CS
Lee
Jin Hee
JH
Kim
Eunhee
E
Nam
Bong Hyun
BH
Park
Joo Hong
JH
Jung
Jin Young
JY
Jang
Dong Deuk
DD
Park
Eun Young
EY
Lee
Kwan-Hee
KH
Ma
Jin-Young
JY
Won
Hey-Sung
HS
Im
Moon-Whan
MW
Leem
Jong-Han
JH
Hong
Yun-Chul
YC
Yoon
Hae-Seong
HS
D000328:Adult; D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors / Q000097:blood*; D004784:Environmental Monitoring; D004968:Estrogens, Non-Steroidal / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D007723:Korea; D018811:Maternal Exposure; D008431:Maternal-Fetal Exchange; D010636:Phenols / Q000097:blood*; D011247:Pregnancy; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D004968:Estrogens, Non-Steroidal; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds