Dehydrogenative cyclocondensation of aldehydes, alkynes, and dialkylsilanes.
The nickel-catalyzed coupling of aldehydes, alkynes, and dialkylsilanes results in an unusual dehydrogenative cyclocondensation process to afford five-membered silacyclic products. The process allows dialkylsilanes to serve as a silylene synthetic equivalent. A mechanistic pathway for the process involving the formation of an aldehyde/alkyne-derived nickel metallacycle followed by sequential sigma-bond metathesis processes involving the two Si-H bonds has been proposed.
Baxter
Ryan D
RD
Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, USA.
Montgomery
John
J