Post-transcriptional control of gene expression through subcellular relocalization of mRNA binding proteins.
Eukaryotic cells have developed multiple mechanisms to respond to different physiological cues, such as cellular stress, which allow the cells to adapt themselves to their new environment. The regulation of post-transcriptional gene expression is an important component of the cellular stress response and is mediated by mRNA binding proteins (mRBPs). Recently, several studies have shown that regulated subcellular localization of mRBPs upon diverse stimuli (such as cellular stress) provides an additional level of regulation for gene expression.
Cammas
Anne
A
INSERM U563, Toulouse F-31000, France.
Lewis
Stephen M
SM
Vagner
Stephan
S
Holcik
Martin
M
D005786:Gene Expression Regulation; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000378:metabolism*; D015398:Signal Transduction; D013347:Subcellular Fractions / Q000378:metabolism*
D012333:RNA, Messenger; D016601:RNA-Binding Proteins