[The use of baclosan in the complex therapy of muscle-tonic and myofascial pain syndromes in patients with dorsopathy].
Baclosan (baclofen), a GABA analogue, has been used in the treatment of 20 patients, aged 20-56 years, with a pain syndrome in dorsopathy of lumbar spine. Baclosan has been administered in the increasing dosages (from 10 mg to 30 mg per day) for 4 weeks in conjunction with traditional therapy (symptomatic pharmacotherapy, physiotherapy, reflexotherapy etc).The control group consisted of 10 patients who received only basic therapy (without baclosan). Patient's status has been measured clinically and with several scales. The results obtained allow to conclude that baclosan exerts a positive effect in the pain syndrome caused by dorsopathy. Its inclusion to the complex therapy reduces both the pain intensity and the degree of muscle-tonic tension as well as improves the motor function and emotional state of patients.
Batysheva
T T
TT
Boĭko
A N
AN
Zaĭtsev
K A
KA
Bagir'
L V
LV
Kostenko
E V
EV
D000328:Adult; D001418:Baclofen / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D001696:Biomechanical Phenomena; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000494:pharmacology* / Q000627:therapeutic use*; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000503:physiopathology*; D009209:Myofascial Pain Syndromes / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D013122:Spinal Diseases / Q000209:etiology*
D009125:Muscle Relaxants, Central; D001418:Baclofen