title: The impact of gestational weight gain and diet on abnormal glucose tolerance during pregnancy in Hispanic women.
abstract: OBJECTIVE
  To examine the association of gestational weight gain and dietary factors with abnormal glucose tolerance (AGT).
  
  
  METHODS
  We conducted a prospective cohort study among 813 Hispanic prenatal care patients in Massachusetts. Gestational weight gain and oral glucose tolerance test results were abstracted from medical records. Dietary intake was assessed using a semi-quantitative food frequency questionnaire. Target weight gain was based on BMI-specific weekly weight gain rates established by the Institute of Medicine (IOM).
  
  
  RESULTS
  We observed a statistically significant interaction between prepregnancy BMI and weight gain in relation to AGT (P < 0.01). Class II/III (BMI > or = 35 kg/m2) obese women who had a high rate of weight gain (>0.30 kg/week) or who exceeded target weight were 3-4 times as likely to develop AGT compared to women who gained within IOM ranges (OR = 4.2, 95% CI 1.1-16.0, OR = 3.2 95% CI 1.0-10.5, respectively). Decreasing levels of saturated fatty acids and energy-dense snack foods and increasing levels of fiber and polyunsaturated:saturated fat ratio were significantly associated with decreased risk of AGT, independent of gestational weight gain [corrected].
  
  
  CONCLUSIONS
  Weight gain among class II/III obese women and certain dietary components may represent modifiable risk factors for AGT.
authors.affiliation: Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, 136 Harrison Avenue, Boston, MA 02111, USA. alison.tovar@tufts.edu
authors.forename: Alison
authors.initials: A
authors.lastname: Tovar
authors.forename: Aviva
authors.initials: A
authors.lastname: Must
authors.forename: Odilia I
authors.initials: OI
authors.lastname: Bermudez
authors.forename: Raymond R
authors.initials: RR
authors.lastname: Hyatt
authors.forename: Lisa
authors.initials: L
authors.lastname: Chasan-Taber
mesh_terms: D000293:Adolescent; D000328:Adult; D016640:Diabetes, Gestational / Q000503:physiopathology; D005247:Feeding Behavior; D005260:Female; D018149:Glucose Intolerance / Q000209:etiology*; D005951:Glucose Tolerance Test; D006630:Hispanic or Latino; D006801:Humans; D008404:Massachusetts; D015596:Nutrition Assessment; D016017:Odds Ratio; D011247:Pregnancy; D011795:Surveys and Questionnaires; D015430:Weight Gain / Q000502:physiology*; D055815:Young Adult