title: Use of propofol for anesthesia in cats with primary hepatic lipidosis: 44 cases (1995-2004).
abstract: OBJECTIVE-To determine morbidity and fatalities in cats with hepatic lipidosis that received propofol to facilitate placement of a feeding tube. STUDY DESIGN-Retrospective case series. ANIMALS-44 Cats with presumed primary hepatic lipidosis anesthetized for placement of a feeding tube. PROCEDURES-Medical records from January 1995 through December 2004 were reviewed to identify cats that matched the inclusion criteria (histologic confirmation of hepatic lipidosis, anesthetized for placement of feeding tube, complete intensive care unit [ICU] records, and recorded outcome). Data extracted included age, body weight, sex, anesthetic drugs, drug dosages, type of feeding tube, duration of anesthesia, number of hours in ICU, administration of blood products, and survival until discharge from ICU. RESULTS-44 Cats (21 females and 23 males) were included in the analysis. Age range was 3 to 15 years (median, 8 years), and body weight ranged from 1.8 to 9.0 kg (4.0 to 19.8 lb), with a median of 4.8 kg (10.6 lb). Twenty-seven cats were administered propofol. There was no significant association between the use of propofol or the dosage of propofol and any risk factor, need for blood products, number of hours in the ICU, or survival. There was no significant difference between cats that received propofol and cats that did not receive propofol with regard to interval until discharge from the ICU. CONCLUSIONS AND CLINICAL RELEVANCE-The use of propofol did not increase morbidity or fatalities in cats with primary hepatic lipidosis. Thus, propofol can be used in these cats for placement of a feeding tube.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Lysa P
authors.initials: LP
authors.lastname: Posner
authors.forename: Makoto
authors.initials: M
authors.lastname: Asakawa
authors.forename: Hollis N
authors.initials: HN
authors.lastname: Erb
mesh_terms: D018686:Anesthetics, Intravenous / Q000009:adverse effects / Q000494:pharmacology*; D000818:Animals; D002371:Cat Diseases / Q000401:mortality / Q000601:surgery*; D002415:Cats; D005260:Female; D007441:Intubation, Gastrointestinal / Q000662:veterinary; D008064:Lipidoses / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D008099:Liver; D008107:Liver Diseases / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D008297:Male; D015742:Propofol / Q000009:adverse effects / Q000494:pharmacology*; D012189:Retrospective Studies
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol