title: Effect of soft laser and bioactive glass on bone regeneration in the treatment of infra-bony defects (a clinical study).
abstract: This study aimed to investigate the influence of low-power 830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated with bioactive glass graft material. Twenty patients with chronic periodontitis and bilateral infra-bony defects were included. Using a split mouth design, we treated 20 defects with bioactive glass plus laser irradiation during surgical procedures and on days 3, 5, 7 postoperatively; 20 contra-lateral defects were treated with bioactive glass only. Clinical probing pocket depths, clinical attachment levels and standardized periapical radiographs were recorded at baseline and at 3 months and 6 months postoperatively. At 3 months there was a statistically significant difference between the laser and non-laser sites in the parameters investigated. However, at 6 months, no difference was observed. Our results have confirmed the positive effect of soft laser in accelerating periodontal wound healing.
authors.affiliation: Department of Oral Medicine and Periodontology, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
authors.forename: Nayer S
authors.initials: NS
authors.lastname: AboElsaad
authors.forename: Mena
authors.initials: M
authors.lastname: Soory
authors.forename: Laila M A
authors.initials: LM
authors.lastname: Gadalla
authors.forename: Laila I
authors.initials: LI
authors.lastname: Ragab
authors.forename: Stephen
authors.initials: S
authors.lastname: Dunne
authors.forename: Khaled R
authors.initials: KR
authors.lastname: Zalata
authors.forename: Chris
authors.initials: C
authors.lastname: Louca
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D001861:Bone Regeneration / Q000187:drug effects* / Q000528:radiation effects*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002516:Ceramics / Q000627:therapeutic use*; D055113:Chronic Periodontitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy; D005260:Female; D006801:Humans; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: C022107:Bioglass; D018786:Bone Substitutes