title: Enhanced affinity of ketotifen toward tamarind seed polysaccharide in comparison with hydroxyethylcellulose and hyaluronic acid: a nuclear magnetic resonance investigation.
abstract: Nuclear magnetic resonance (NMR) spectroscopy demonstrated that, in aqueous solution, ketotifen fumarate bound more strongly to tamarind seed polysaccharide (TSP) than to hydroxyethylcellulose or hyaluronic acid. Results were confirmed by dynamic dialysis technique.
authors.affiliation: Università di Pisa, Dipartimento di Chimica e Chimica Industriale, Via Risorgimento 35, I-56126 Pisa, Italy. gub@dcci.unipi.it
authors.forename: Gloria
authors.initials: G
authors.lastname: Uccello-Barretta
authors.forename: Samuele
authors.initials: S
authors.lastname: Nazzi
authors.forename: Federica
authors.initials: F
authors.lastname: Balzano
authors.forename: Giacomo
authors.initials: G
authors.lastname: Di Colo
authors.forename: Ylenia
authors.initials: Y
authors.lastname: Zambito
authors.forename: Chiara
authors.initials: C
authors.lastname: Zaino
authors.forename: Marco
authors.initials: M
authors.lastname: Sansò
authors.forename: Eleonora
authors.initials: E
authors.lastname: Salvadori
authors.forename: Marco
authors.initials: M
authors.lastname: Benvenuti
mesh_terms: D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D006820:Hyaluronic Acid / Q000737:chemistry*; D007665:Ketotifen / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011134:Polysaccharides / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D013329:Structure-Activity Relationship; D029861:Tamarindus / Q000737:chemistry*
chemical_list: D011134:Polysaccharides; D002482:Cellulose; D006820:Hyaluronic Acid; C002283:hydroxyethylcellulose; D007665:Ketotifen