title: Detection of structure-switching in G-quadruplexes using end-stacking ability.
abstract: G-quadruplex-forming ODNs containing nonpolar aromatic fluorophore moiety, A(PY) at the dangling ends undergo pi-stacking on surface of G-quadruplex, and the fluorescence change can be used to distinguish the structure-switching between the mixed parallel/antiparallel structure and antiparallel structure.
authors.affiliation: Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.
authors.forename: Young Jun
authors.initials: YJ
authors.lastname: Seo
authors.forename: Il Joon
authors.initials: IJ
authors.lastname: Lee
authors.forename: Byeang Hyean
authors.initials: BH
authors.lastname: Kim
mesh_terms: D001483:Base Sequence; D002626:Chemistry, Pharmaceutical / Q000379:methods; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry; D015195:Drug Design; D005456:Fluorescent Dyes / Q000737:chemistry; D054856:G-Quadruplexes; D008956:Models, Chemical; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*; D013696:Temperature
chemical_list: D005456:Fluorescent Dyes; D009841:Oligonucleotides; D004247:DNA