title: [Observe effect of treating C-IBS by Tongyouqing].
abstract: OBJECTIVE
  To explore the effect of Tongyouqing treating the C-IBS.
  
  
  METHODS
  According to rome standard II, fifty-eithy C-IBS patients were randomly divided into two groups. Control group (28 cases) were given tijiaseluo (6 mg, qd). Treatment group (30 cases) were given Tongyouqing. After treatment for 4 weeks, observing and comparing the two groups IBS symptom between treatment before and later (Bristol score, abdominal distention, abdominal angina, constipation, partial defecation, belch, mind). To understand the condition of the colonic dynamic by colonic transit trial. Comparing the effective rate of the two group and the proportion of patients still choosing the medicine which they were given.
  
  
  RESULTS
  The symptom score of the two groups patients, there were signifi-cant differences between the two groups before treatment and after treatment (P <0.05). After treatment, treatment group is prefer to control group in the improvement of the colonic dynamic (P <0.05). The effective rate and the proportion of patients still choosing the medicine which they were given of treatment group is also more higher than control group.
  
  
  CONCLUSIONS
  Tongyouqing can relieve the gastrointestinal symptom, improve the fecal character, lessen abdominal distention and abdominal angina, increase the defecating times, improve the colonic dynamic, improve the mind state quilkly and manifestly. Tongyouqing is an effective method to treat C-IBS. It deserves clinical spreading, its mechnism needs further study.
authors.affiliation: Guangzhou Hospital of Traditional Chinese Medicine, Guangzhou 510130, China. zdjlyh@126.com
authors.forename: Yong-Hui
authors.initials: YH
authors.lastname: Lv
authors.forename: Yun-Peng
authors.initials: YP
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003106:Colon / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal; C540318:Tongyouqing