title: Brain natriuretic peptides as biomarkers for atherosclerosis.
abstract: Identification of atherosclerotic risk factors provides targets for development of preventive therapies. Risk factor assessment permits evaluation of an individual's prospective risk of coronary heart disease (CHD). However, it has become apparent that traditional risk factors may not predict CHD in some patients. As a result, many individuals do not receive the benefit of intensive preventive strategies. Accordingly, considerable effort has focused on the identification of novel biomarkers to enhance risk stratification. Given its prognostic utility in heart failure and acute coronary syndrome, brain natriuretic peptide (BNP) and its amino-terminal fragment have received interest as possible biomarkers for CHD.
authors.affiliation: Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: Kellan E
authors.initials: KE
authors.lastname: Ashley
authors.forename: John M
authors.initials: JM
authors.lastname: Galla
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Nicholls
mesh_terms: D050197:Atherosclerosis / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain