title: Vincristine-induced paralytic ileus in Parkinson's disease.
abstract: We present an elderly patient with metastatic breast cancer and Parkinson's disease (PD) of moderate severity who developed paralytic ileus of protracted course after a low dose of 0.16 mg/m(2) intravenous vincristine. Since colonic myenteric plexus involvement occurs in PD, we suggest that it may predispose to vinca alkaloids-induced autonomic neuropathy. Vincristine should be used with caution in this clinical setup.
authors.affiliation: Department of Neurology, Hadassah University Hospital, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
authors.forename: R R
authors.initials: RR
authors.lastname: Leker
authors.forename: T
authors.initials: T
authors.lastname: Peretz
authors.forename: A
authors.initials: A
authors.lastname: Hubert
authors.forename: A
authors.initials: A
authors.lastname: Lossos