title: [Study on anti-diabetes active fraction and constituents from Potentilla chinesis].
abstract: OBJECTIVE
  To study the active fraction and constituents from Potentilla chinesis.
  
  
  METHODS
  Tested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.
  
  
  RESULTS
  The fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).
  
  
  CONCLUSIONS
  Fraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.
authors.affiliation: School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhao
authors.forename: Wei
authors.initials: W
authors.lastname: Qiao
authors.forename: Yan-Wen
authors.initials: YW
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Lu
authors.forename: Hong-Quan
authors.initials: HQ
authors.lastname: Duan
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D047309:Flavones; D005419:Flavonoids / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D031987:Potentilla / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D047309:Flavones; D005419:Flavonoids; D007004:Hypoglycemic Agents; C043562:flavone