Oxygen homeostasis: how the worm adapts to variable oxygen levels.
A recent study has found that activation of the hypoxia-inducible transcription factor HIF in the nematode Caenorhabditis elegans can alter oxygen preferences and dramatically re-wire the neuronal circuit required for avoiding high oxygen levels.
Branicky
Robyn S
RS
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Schafer
William R
WR
D000222:Adaptation, Physiological; D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D006706:Homeostasis; D051793:Hypoxia-Inducible Factor 1 / Q000378:metabolism*; D009424:Nervous System Physiological Phenomena; D010100:Oxygen / Q000502:physiology*
D051793:Hypoxia-Inducible Factor 1; D010100:Oxygen