Chuktabrins A and B, two novel limonoids from the twigs and leaves of Chukrasia tabularis.
Two novel limonoids, chuktabrin A (1), featuring the unique motifs of a 1,3-dioxolan-2-one and a 3,4-dihydro-2 H-pyran, and chuktabrin B (2), possessing an unprecedented polycyclic skeleton, were isolated from Chukrasia tabularis. The structures of 1 and 2 bearing a biosynthetically extended C3 and C2 unit at C-15, respectively, were elucidated on the basis of spectroscopic data, and that of 1 was confirmed by a single-crystal X-ray diffraction.
Zhang
Chuan-Rui
CR
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
Fan
Cheng-Qi
CQ
Zhang
Li
L
Yang
Sheng-Ping
SP
Wu
Yan
Y
Lu
Yang
Y
Yue
Jian-Min
JM
D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification; D029582:Meliaceae / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D014961:X-Ray Diffraction
D036701:Limonins