title: Use of the amniotic fluid index combined with estimated fetal weight within 10 days of delivery for prediction of macrosomia at birth.
abstract: OBJECTIVE
  The purpose of this study was to assess the value of combining the sonographically estimated fetal weight (EFW) and amniotic fluid index (AFI) measured within 10 days of term delivery for prediction of macrosomia at birth.
  
  
  METHODS
  Prospective sonographic fetal biometric measurements and delivery ward data of a single center, uploaded separately over a 4-year period, were retrospectively linked to yield an unselected sample of nondiabetic pregnancies with live-born term neonates.
  
  
  RESULTS
  Of the 1925 pregnancies evaluated, 140 (7.2%) were macrosomic (birth weight > or =4000 g). The AFI was significantly higher in the macrosomic group (P < .001). On receiver operating characteristic curve analysis, the area under the curve was larger for predictions based on the EFW alone than on the AFI. An EFW of 4000 g or higher had a positive predictive value of 46.6% for macrosomia at birth. Use of the previously suggested combined EFW and AFI cutoffs of 3689 g and 119 mm, respectively, yielded a positive predictive value of 30.3%.
  
  
  CONCLUSIONS
  Combined use of the EFW and AFI rather than the EFW alone does not improve prediction of macrosomia at birth.
authors.affiliation: Department of Obstetrics and Gynecology, Helen Schneider's Hospital for Women, Rabin Medical Center, 49100 Petach Tikva, Israel. yudavi@inter.net.il
authors.forename: Avi
authors.initials: A
authors.lastname: Ben-Haroush
authors.forename: Nir
authors.initials: N
authors.lastname: Melamed
authors.forename: Reuven
authors.initials: R
authors.lastname: Mashiach
authors.forename: Israel
authors.initials: I
authors.lastname: Meizner
authors.forename: Yariv
authors.initials: Y
authors.lastname: Yogev
mesh_terms: D000653:Amniotic Fluid / Q000000981:diagnostic imaging; D019540:Area Under Curve; D001699:Biometry; D005260:Female; D005320:Fetal Macrosomia / Q000175:diagnosis* / Q000000981:diagnostic imaging; D020567:Fetal Weight; D005865:Gestational Age; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011247:Pregnancy; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods*