Brain metastasis from thymic carcinoma in association with SIADH and pituitary enlargement: a case report.
A 49-year-old white female presented to the emergency room complaining of severe headaches. A brain computed tomography (CT) showed a large right temporal mass that measured 2.9 x 5 cm. Sodium was low at admission, which indicated syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Her pituitary gland was enlarged. Thorax CT revealed a large anterior mediastinal mass measuring 6.3 x 3.6 cm. Pathology revealed a poorly differentiated carcinoma arising from the thymus. This case is unique because thymic cancer rarely results in brain metastases and very rarely causes SIADH with changes in pituitary volume and signal quality.
Walid
Mohammad Sami
MS
Medical Center of Central Georgia, Georgia Neurosurgical Institute, Macon, GA 31201, USA. mswalid@yahoo.com
Troup
Earl Christopher
EC
Robinson
Joe Sam
JS
D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000556:secondary; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007010:Hyponatremia / Q000209:etiology; D007177:Inappropriate ADH Syndrome / Q000150:complications*; D008875:Middle Aged; D008881:Migraine Disorders / Q000209:etiology; D010902:Pituitary Gland / Q000473:pathology*; D013945:Thymoma / Q000150:complications* / Q000556:secondary; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000473:pathology