title: Relationship between ankle-brachial index and carotid intima-media thickness in HIV-infected patients.
abstract: Both low and high ankle-brachial index are considered as indicators of systemic atherosclerosis in older HIV-negative adults. Whether those ankle-brachial index values are predictors of atherosclerosis in HIV-positive subjects remains unknown. We measured ankle-brachial index in 139 HIV-infected patients and compared the results obtained with carotid intima-media thickness, a well established marker of subclinic atherosclerosis. Ankle-brachial index was associated with carotid intima-media thickness. Patients with low ankle-brachial index, but not those with high ankle-brachial index, had high carotid intima-media thickness.
authors.affiliation: Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain.
authors.forename: Félix
authors.initials: F
authors.lastname: Gutiérrez
authors.forename: Enrique
authors.initials: E
authors.lastname: Bernal
authors.forename: Sergio
authors.initials: S
authors.lastname: Padilla
authors.forename: Ildefonso
authors.initials: I
authors.lastname: Hernández
authors.forename: Mar
authors.initials: M
authors.lastname: Masiá
mesh_terms: D000328:Adult; D000368:Aged; D000842:Ankle / Q000098:blood supply; D001916:Brachial Artery / Q000503:physiopathology*; D002340:Carotid Artery Diseases / Q000175:diagnosis* / Q000209:etiology; D017536:Carotid Artery, Common / Q000473:pathology*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D017539:Tunica Intima / Q000473:pathology; D017540:Tunica Media / Q000473:pathology