title: [Functional changes in the cardioesophageal region following laparoscopic fundoplication].
abstract: Functional changes of antireflux mechanisms after laparoscopic fundpolication.
  
  
  OBJECTIVE
  To examine manometry and pH-study in evaluation of the changes in measurable features of antireflux mechanisms after fundoplication for gastro-oesophageal reflux disease.
  
  
  METHODS
  Laparoscopic Nissen-Rossetti fundoplications with hiatorhaphy were performed in patients with gastroesophageal reflux disease. Preoperative and postoperative manometry and pH-study were compared in set of twenty satisfied orjerated without any complaints after surgery who agreed with preoperative and postoperative examinations.
  
  
  RESULTS
  Higher length of lower esophageal sphincter following antireflux fundoplication (P = 0.0003), increased tone of lower esophageal sphincter with antireflux fundoplication (P = 0.0001) and lower value of pH-study after fundoplication (P = 0.0001) were observed.
  
  
  CONCLUSIONS
  Postoperative manometry and pH-study effectively evaluated gastro-oesophageal reflux changes following fundoplication for gastro-oesophageal reflux disease.
authors.affiliation: I. chirurgická klinika FN Olomouc. mlovecek@seznam.cz
authors.forename: M
authors.initials: M
authors.lastname: Lovecek
authors.forename: R
authors.initials: R
authors.lastname: Vrba
authors.forename: R
authors.initials: R
authors.lastname: Aujeský
authors.forename: C
authors.initials: C
authors.lastname: Neoral
mesh_terms: D002299:Cardia / Q000503:physiopathology; D049630:Esophageal Sphincter, Lower / Q000503:physiopathology*; D050782:Esophageal pH Monitoring; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D008365:Manometry