Thrombotic thrombocytopenic purpura associated with multiple myeloma.
Thrombotic thrombocytopenic purpura is a thrombotic microangiopathic disease. Associations with collagen vascular diseases, pregnancy, some drugs, surgical intervention, and infections are documented (known). Malignancy is also one of the known factors associated with thrombotic thrombocytopenic purpura. These malignancies are usually the disseminated solid organ tumors. Hematological malignancies constitute a rare association. Here, we present a patient with thrombotic thrombocytopenic purpura associated with multiple myeloma and discuss the pathogenesis. To our knowledge, this is the first case report of thrombotic thrombocytopenic purpura associated with multiple myeloma.
Alpay
Nilufer
N
Department of Internal Medicine, Istanbul Medical School, Istanbul University, Istanbul, Turkey. nalpay@istanbul.edu.tr
Uzun
Sami
S
Bahat
Gulistan
G
Yavuz
Selim
S
Erten
Nilgun
N
Tascioglu
Cemil
C
D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood / Q000150:complications* / Q000473:pathology*; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000150:complications* / Q000473:pathology*