title: Intermediate scale for assessment of Parkinson's disease. Characteristics and structure.
abstract: The present study is devoted to the verification of the basic metrical characteristics of the ISAPD. One hundred and sixty-seven Parkinson's disease (PD) patients were included. Group A (n = 40) was simultaneously assessed by five raters who applied the ISAPD and other PD rating scales (PDRS). A set of timed tests, the MiniMental State Examination (MMSE) and the Hamilton Scale for Depression (HSD) were administered by an independent examiner. Group B (n = 127) was individually assessed through the UPDRS and the other PDRSs by separate neurologists in four different hospitals. The ISAPD was administered in 7.0 +/- 3.7 min. The internal consistency of this scale was high (Cronbach's alpha = 0.97). The inter-rater reliability of their items was very satisfactory (for all items, kappa > 0.70). There was a high correlation with the Hoehn and Yahr classification (r(s) = 0.71; p < 0.001) and some timed tests. The convergent validity with the other PDRS (UPDRS and Schwab and England Scale) was also very high (r(s) = 0.83-0.92; p < 0.001). The ISAPD also correlated with the MMSE and the HSD. Factor analysis identified three factors (activities of daily living; gait and mobility; speech and eating) that explained 76% of the variance. The ISAPD is an easy to apply, reliable, and valid scale that fulfills the aim for which it was designed.
authors.affiliation: The Cooperative Multicentric Group, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Martínez-Martin
authors.forename: A
authors.initials: A
authors.lastname: Gil-Nagel
authors.forename: L
authors.initials: L
authors.lastname: Morlán Gracia
authors.forename: J
authors.initials: J
authors.lastname: Balseiro Gómez
authors.forename: F J
authors.initials: FJ
authors.lastname: Martínez-Sarriés
authors.forename: F
authors.initials: F
authors.lastname: Bermejo
authors.forename: T
authors.initials: T
authors.lastname: Del Ser Quijano
authors.forename: M C
authors.initials: MC
authors.lastname: Macías
authors.forename: C
authors.initials: C
authors.lastname: Jiménez-Rojas
authors.forename: E
authors.initials: E
authors.lastname: Marañón
authors.forename: J M
authors.initials: JM
authors.lastname: Grau Veciana
authors.forename: C
authors.initials: C
authors.lastname: Roig Arnall
authors.forename: O
authors.initials: O
authors.lastname: Bruna
authors.forename: C
authors.initials: C
authors.lastname: Junquéplaja
authors.forename: S
authors.initials: S
authors.lastname: Giménez-Roldán
authors.forename: J A
authors.initials: JA
authors.lastname: Burguera