title: [Discuss of efficacy study to traditional Chinese medicine complex prescription].
abstract: There are many differences between traditional Chinese medicine (TCM) and western medicine, and the use of TCM has its feature under the guide of TCM theory. Determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs is the base of TCM treatment, the main form of TCM apply is compatibility, formula corresponding differentiation of symptoms and signs is the key for TCM to get better effects, integrated adjustment is the TCM mode of action. All above determined the methods and standards to evaluate the pharmacodynamic effect of TCM cannot completely accord to Western medicine. Use modern technology and combine the feature of TCM to estabilish the method for effects evaluation and standard system of TCM, which is the key point to correctly appraise the effects of TCM. Stabilized quality control is the precondition of pharmacodynamic action appraisement, animal models combined disease and symptoms are the necessary tools for effect appraisement, integrated adjustment need mutiple index to appraise pharmacodynamic action, the method to avoid subjective error in TCM reseach is using mathematical model and parameter to scientificly analyse data, also the explaination of mechanism of action need standard clinical pharmacology experimental date.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Guo
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000592:standards; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods* / Q000592:standards; D008954:Models, Biological; D011786:Quality Control; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal