Case of generalised myasthenia gravis with membranous nephropathy.
We report a 40-year old woman with bilateral partial ptosis, complete external ophthalmoplegia, and weakness and fatiguability of upper limbs. She was on treatment for hypertension for 5 months at the time of admission. She was found to have generalised myasthenia gravis and membranous nephropathy with end-stage renal disease. Her symptoms and signs improved within 2 months on treatment with neostigmine and prednisolone. It is postulated that either thymic hyperplasia or the subclinical stage of a thymoma may be the underlying aetiological factor in this patient.
Prasad
K P Ruwan C
KP
Teaching Hospital, Kandy, Sri Lanka. ruwan@med.ruh.ac.lk
Alahakoon
D G S
DG
Vidanagama
U
U
D000328:Adult; D001763:Blepharoptosis / Q000188:drug therapy / Q000209:etiology; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D009388:Neostigmine / Q000627:therapeutic use; D009886:Ophthalmoplegia / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D013945:Thymoma / Q000150:complications; D013952:Thymus Hyperplasia / Q000150:complications; D013953:Thymus Neoplasms / Q000150:complications; D016896:Treatment Outcome
D009388:Neostigmine; D011239:Prednisolone