title: [Analysis of the spatial-temporal EEG organization as the way to the knowledge of neurophysiological mechanisms of the integrative brain activity].
abstract: Short results' review of investigations of Laboratory of Neurophysiology of Child of Sechenov Institute is presented in the article. Investigations are based on concept of academic M.N. Livanov about special role of spatial-temporal relations of brain potentials oscillations of various brain areas in providing of functional connection between them. It is shown, that in rest condition the structure of interregional relations of cortex biopotentials in all healthy people is characterized by high spatial orderliness that obviously assists to optimal realization of informational processes during various functional conditions from rest to complex cognitive functions. Special attention is given for the problem of functional signigicance of phase shifts of EEG waves. Data, that allows concluding that brainstem and thalamocartical integrative systems are characterized with relatively small inherited and phenotypic variability whereas fiber systems of both hemispheres that provide processes of intercortical integration are characterized by more expressed inter-individual variability, is presented. Intensive development of long associative and commissural tracks of telencephalon that joined even the most distanced cortical regions of hemispheres in united formation apparently results in formation of morpho-functional "skeleton" of neocortex, that occurred to be the basis for origin of qualitatively new (in comparison to animals) principals of formation of system organization of integral activity of the brain. Existence of long mono- and oligo-synaptic connections provides conditions for correlative develoment in ontogenesis of new function that is not conditioned by phylogenetic development.
authors.forename: A N
authors.initials: AN
authors.lastname: Shepoval'nikov
authors.forename: M N
authors.initials: MN
authors.lastname: Tsitseroshin
mesh_terms: D001921:Brain / Q000254:growth & development / Q000502:physiology*; D001931:Brain Mapping; D003344:Cortical Synchronization; D004569:Electroencephalography; D006801:Humans