A roadmap to disentangle the molecular etiology of schizophrenia.
Schizophrenia is a severe mental disorder striking mainly young adults and leading to life-long disability in a substantial portion of the sufferers. On the other hand, substantial knowledge about its etiology and pathogenesis is still lacking. Therefore the European Science Foundation (ESF) sponsored a meeting of a panel of European experts on schizophrenia research to discuss the state of art and future perspectives of key topics in this area. The fields covered genetics, epidemiology, animal models, molecular neuropathology and imaging. This was a first step to establish a network of European groups dedicated to Schizophrenia research. The coming calls of the frame work program will be used to strengthen this network in order to achieve substantial progress in understanding and treating this devastating illness.
Falkai
Peter
P
Department of Psychiatry and Psychotherapy, University of Goettingen, Von-Siebold-Strasse 5, 37075 Goettingen, Germany. pfalkai@gwdg.de
Mike
Owen
O
Inez
Myin-Germeys
MG
Paul
Harrison
H
Andras
Bilkei-Gorzo
BG
Sophia
Frangou
F
D000818:Animals; D001921:Brain / Q000473:pathology; D003430:Cross-Sectional Studies; D003952:Diagnostic Imaging; D004195:Disease Models, Animal; D004843:Epistasis, Genetic; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008126:Lod Score; D009419:Nerve Tissue Proteins / Q000235:genetics; D020890:Neuregulin-1; D012559:Schizophrenia / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology
C094131:NRG1 protein, human; D009419:Nerve Tissue Proteins; D020890:Neuregulin-1