[Goodpasture's syndrome].
Goodpasture s syndrome (GS) is an auto-immune disease that is part of the pulmonary-renal syndrome spectrum. It is characterized by the linear deposition of anti-glomerular basement membrane antibodies (anti-GBM) in glomerular and alveolar basement membrane resulting in alveolar hemorrhage and progressive glomerulonephritis. An early diagnosis is important to decrease clinical morbidity. In the present work we illustrate a GS case initially diagnosed as Wegener s granulomatosis. The patient showed favorable clinical evolution with corticosteroid therapy associated with plasmapheresis and cyclophosphamide.
Shinjo
Samuel Katsuyuki
SK
Disciplina da Reumatologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil. samuel.shinjo@gmail.com
Hasegawa
Eduardo Massato
EM
Costa Malheiros
Denise Maria Avancini
DM
Levy-Neto
Mauricio
M
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male