Hydrodynamic model for liquid-impelled loop reactors.
A new type of bioreactor, in which two liquid phases are used, is introduced and a model description of its hydrodynamic behavior is given. The model is based on the two-phase drift-flux model of Zuber and Findlay and on a friction coefficient derived from one-phase flow theory. Drop sizes, necessary for model calculations, were estimated from literature correlations and photographically verified. The model predicts the continuous-phase circulation velocity and dispersed-phase hold-up within an accuracy of 5% for a pilot-plant reactor, and within 10% for a lab-scale reactor. Only at very low ranges, especially on lab scale, is this accuracy not attained.
van Sonsbeek
H M
HM
Food and Bioprocess Engineering Group, Department of Food Science, Agricultural University Wageningen, 6700 EV Wageningen, The Netherlands.
Verdurmen
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Verlaan
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Tramper
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