Senescence triggered by the loss of the VHL tumor suppressor.
Young
Arthur P
AP
Department of Developmental and Stem Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA. arthur.young@joslin.harvard.edu
Kaelin
William G
WG
D000818:Animals; D016922:Cellular Senescence / Q000235:genetics*; D017353:Gene Deletion; D020022:Genetic Predisposition to Disease; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000235:genetics*; D051794:Von Hippel-Lindau Tumor Suppressor Protein / Q000235:genetics*
D051794:Von Hippel-Lindau Tumor Suppressor Protein; C497446:VHL protein, human; C494469:VHL protein, mouse