Soluble RNA methylase activity of transplantable mouse hepatomas.
The soluble ribonucleic acid (sRNA) methylase activity and the histology of several transplantable mouse hepatomas were examined. Three hepatomas (H-1, H-4, and H-6) were relatively fast growing. H-1 and H-6 hepatomas had higher sRNA methylase activity, H-4 had amounts of activity similar to those of liver, and H-3 hepatoma had variable amounts. sRNA methylase activity did not seem to be correlated with rate of growth but may have been associated with the state of differentiation.
Hancock
R L
RL
Division of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
Grunau
J
J
D000818:Animals; D002454:Cell Differentiation; D005260:Female; D008114:Liver Neoplasms, Experimental / Q000201:enzymology* / Q000473:pathology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D012995:Solubility; D012359:tRNA Methyltransferases / Q000378:metabolism*
D012359:tRNA Methyltransferases