title: [Photodynamic therapy in vulvar intraepithelial neoplasia].
abstract: BACKGROUND
  Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).
  
  
  METHODS
  The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).
  
  
  METHODS
  We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva.
  
  
  CONCLUSIONS
  We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree.
authors.affiliation: Katedra i Oddział Kliniczny Ginekologii, Połoznictwa i Ginekologii Onkologicznej SIUM w Bytomiu, Bytom. anitaolejek@wp.pl
authors.forename: Anita
authors.initials: A
authors.lastname: Olejek
authors.forename: Iwona
authors.initials: I
authors.lastname: Kozak-Darmas
authors.forename: Tomasz
authors.initials: T
authors.lastname: Biniszkiewicz
authors.forename: Sylwia
authors.initials: S
authors.lastname: Kellas-Sleczka
authors.forename: Aleksander
authors.initials: A
authors.lastname: Sieroń
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000622:Aminolevulinic Acid / Q000008:administration & dosage*; D002278:Carcinoma in Situ / Q000188:drug therapy* / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D011044:Poland; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid