title: Case of acute generalized exanthematous pustulosis caused by ampicillin/cloxacillin sodium in a pregnant woman.
abstract: We report a case of acute generalized exanthematous pustulosis (AGEP) induced by ampicillin/cloxacillin sodium (ABPC/MCIPC) in a pregnant woman. AGEP is caused mostly by drugs. Among them, beta-lactam antibiotics account for a high proportion of the cases, predominantly by amoxicillin. To our knowledge, this is only the second case ever reported in the Japanese language published work of AGEP induced by ABPC/MCIPC.
authors.affiliation: Department of Dermatology, Tokyo Medical University, Tokyo, Japan. yukamat@aol.com
authors.forename: Yuka
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Yukari
authors.initials: Y
authors.lastname: Okubo
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Ito
authors.forename: Ryoji
authors.initials: R
authors.lastname: Tsuboi
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003023:Cloxacillin / Q000008:administration & dosage / Q000009:adverse effects*; D004338:Drug Combinations; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005076:Exanthema / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D010328:Patch Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology; D013290:Streptococcal Infections / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D000658:Amoxicillin; D003023:Cloxacillin