title: Is anxiety sensitivity a predictor of PTSD in children and adolescents?
abstract: OBJECTIVE
  Anxiety sensitivity (AS) is the fear of the physical symptoms of anxiety and related symptoms. Longitudinal studies support AS as a vulnerability factor for development of anxiety disorders. This study aimed to investigate AS as a vulnerability factor in the development of childhood posttraumatic stress disorder (PTSD) following traumatic experiences.
  
  
  METHODS
  The study included 81 children 8-15 years of age who experienced the 1999 earthquake in Bolu, Turkey. The earthquake survivors were compared to a randomized group of age- and sex-matched controls 5 years after the earthquake. Both the subject and control groups were administered the Childhood Anxiety Sensitivity Index (CASI), State and Trait Anxiety Inventory for Children (STAI-C), and Child Depression Inventory (CDI), while the PTSD symptoms of the subjects were assessed using the Child Posttraumatic Stress Reaction Index (CPTS-RI).
  
  
  RESULTS
  Subjects and controls did not differ significantly in CASI, STAI-C, or CDI scores. Multiple regression analysis showed that both trait anxiety and CASI scores predicted CPTS-RI scores of the subjects; the prediction by CASI scores was over and above the effect of trait anxiety.
  
  
  CONCLUSIONS
  The results of this study support the hypothesis that AS may be a constitutional factor, which might increase the risk of PTSD following traumatic experiences.
authors.affiliation: Department of Child Psychiatry, Medical School, Ankara University, Ankara, Turkey.
authors.forename: Emine Zinnur
authors.initials: EZ
authors.lastname: Kiliç
authors.forename: Cengiz
authors.initials: C
authors.lastname: Kiliç
authors.forename: Savaş
authors.initials: S
authors.lastname: Yilmaz
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001007:Anxiety / Q000175:diagnosis* / Q000523:psychology; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D002648:Child; D035061:Control Groups; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004190:Disasters / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D010551:Personality / Q000145:classification; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011237:Predictive Value of Tests; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology; D014421:Turkey / Q000453:epidemiology