[The role of some cell regeneration markers of epithelial cells in genesis of gastric tumors associated with H. pylori].
It is established, that chronic atrophic gastritis adenomatous polyps and gastric cancer are consecutive stages of gastric mucous tunic cell renovation disturbance, manifests itself in progressive delay its apoptosis activity from proliferation, which reflects increase in expression Ki-67 and Bcl-2. Eradication of Helicobacter pylori shorts activity and reduces intensity of inflammatory process in gastric mucous tunic and improves indices of cell renovation.
Osadchuk
A M
AM
Osadchuk
M A
MA
Kvetnoĭ
I M
IM
D017209:Apoptosis / Q000502:physiology*; D014408:Biomarkers, Tumor / Q000096:biosynthesis; D001706:Biopsy; D049109:Cell Proliferation; D018450:Disease Progression; D004847:Epithelial Cells / Q000378:metabolism / Q000473:pathology; D005753:Gastric Mucosa / Q000378:metabolism / Q000382:microbiology / Q000473:pathology*; D005757:Gastritis, Atrophic / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000096:biosynthesis; D011230:Precancerous Conditions; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis; D013274:Stomach Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology*
D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D019253:Proto-Oncogene Proteins c-bcl-2