title: Postinfectious focal necrotizing myopathy.
abstract: A 37-year-old woman was admitted to our department with general fatigue, fever, and asymmetric pain in her lower legs, 2 weeks after a common cold. Dynamic skeletal scintigraphy with 780 MBq (20 mCi) Tc-99m HDP revealed increased perfusion and tracer uptake in the soft tissue of the lower legs, suggesting an inflammatory etiology. A muscle biopsy revealed a vasculitic necrotizing myopathy predominantly affecting the small vessels of the lower legs. We diagnosed it as a postinfectious immunologic reaction.
authors.affiliation: Department of Neurology, University Hospital, University of Cologne, Cologne, Germany. sylviaderyk@hotmail.com
authors.forename: Manuel
authors.initials: M
authors.lastname: Dafotakis
authors.forename: Roland
authors.initials: R
authors.lastname: Sparing
authors.forename: Simon B
authors.initials: SB
authors.lastname: Eickhoff
authors.forename: Christian
authors.initials: C
authors.lastname: Boy
authors.forename: Stefan
authors.initials: S
authors.lastname: Nikolin
authors.forename: Gereon R
authors.initials: GR
authors.lastname: Fink
mesh_terms: D000328:Adult; D001706:Biopsy; D003139:Common Cold / Q000150:complications; D004576:Electromyography / Q000379:methods; D005260:Female; D006801:Humans; D007249:Inflammation; D018482:Muscle, Skeletal / Q000473:pathology; D009135:Muscular Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D009336:Necrosis / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging / Q000379:methods*; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate