[New tumour markers useful in diagnostics and monitoring of cervical cancer].
Cervical carcinoma is the most frequent disease of the female reproductive organs. The tumour markers may be helpful: in early diagnosis of cervical cancer, the initial assesment of the extent of the disease, monitoring of tumour growth or tumour volume reduction, recurrence of cancer, and have been used for monitoring of the clinical course of chemotherapy and radiotherapy. In this paper we have focused on the role of new tumour markers, especially cytokines (for example G-CSF, VEGF) and molecular markers of carcinogenesis (for example Bcl-2 and p53), in comparison to typical tumour markers useful in diagnostic of cervical cancer such as CA 125, SCC-Ag, TPA, TPS, CYFRA 21-1.
Bedkowska
Grazyna Ewa
GE
Zakład Diagnostyki Biochemicznej, Akademii Medycznej w Białymstoku. zdb@amb.edu.pl
Lawicki
Sławomir
S
Szmitkowski
Maciej
M
D000951:Antigens, Neoplasm / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000097:blood; D006801:Humans; D010455:Peptides / Q000097:blood; D015843:Serpins / Q000097:blood; D019396:Tissue Polypeptide Antigen / Q000097:blood; D002583:Uterine Cervical Neoplasms / Q000097:blood / Q000175:diagnosis*; D042461:Vascular Endothelial Growth Factor A / Q000097:blood
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D010455:Peptides; D015843:Serpins; D019396:Tissue Polypeptide Antigen; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; C051072:squamous cell carcinoma-related antigen; C089984:tissue polypeptide specific antigen; D016179:Granulocyte Colony-Stimulating Factor