Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling.
Cardoso
B A
BA
Martins
L R
LR
Santos
C I
CI
Nadler
L M
LM
Boussiotis
V A
VA
Cardoso
A A
AA
Barata
J T
JT
D049109:Cell Proliferation; D006801:Humans; D015847:Interleukin-4 / Q000502:physiology*; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D011494:Protein Kinases / Q000378:metabolism*; D015398:Signal Transduction; D058570:TOR Serine-Threonine Kinases; D014407:Tumor Cells, Cultured
D015847:Interleukin-4; D011494:Protein Kinases; C546842:MTOR protein, human; D058570:TOR Serine-Threonine Kinases