title: Allele frequencies of 11 X-chromosomal loci in a population sample from Ghana.
abstract: Eleven X-chromosomal short tandem repeats (STRs) from two multiplex PCR approaches (DXS6807, DXS8378, DXS7132, DXS6800, DXS9898, DXS7424, DXS101, DXS7133, HPRTB, DXS8377, and DXS7423), located in four different X-chromosomal linkage groups, were typed in a population sample from Ghana, Africa. After genotyping unrelated men (129) and women (114) from the Ashanti population, forensic efficiency parameters such as polymorphism information content and mean exclusion chance were calculated. A deviation from the Hardy-Weinberg equilibrium could not be found. The investigation of 11 father-daughter and seven mother-son meioses revealed no mutations in any STR analyzed. Our data were compared with European, African-American, and Asian populations from the literature.
authors.affiliation: Institute of Forensic Medicine, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany. micaela.poetsch@uk-essen.de
authors.forename: Micaela
authors.initials: M
authors.lastname: Poetsch
authors.forename: Daniela
authors.initials: D
authors.lastname: El-Mostaqim
authors.forename: Frank
authors.initials: F
authors.lastname: Tschentscher
authors.forename: Edmund N L
authors.initials: EN
authors.lastname: Browne
authors.forename: Christian
authors.initials: C
authors.lastname: Timmann
authors.forename: Rolf D
authors.initials: RD
authors.lastname: Horstmann
authors.forename: Nicole
authors.initials: N
authors.lastname: von Wurmb-Schwark
mesh_terms: D041321:Chromosomes, Human, X; D016172:DNA Fingerprinting; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005869:Ghana; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences