Control of an Escherichia coli mixed culture via affinity binding.
A chemostat with population specific recycle was employed to alter the dynamics of a competitive mixed culture of Escherichia coli. Based on differential expression of a functional maltoporin, the two populations were separated by specific adhesion on starch-Sepharose. The slower growing population was the recycled to the reactor. The specific recycle was successful in maintaining the slower growing population at a high level than in comparable reactors without recycle.
Roos
J W
JW
Department of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Hjortso
M A
MA