title: Fluoroscopy guided instillation therapy in chyluria using combination of povidone iodine with contrast agent. Is a single instillation sufficient?
abstract: OBJECTIVE
  To evaluate the safety and efficacy of a single instillation in a combination of povidone iodine with contrast agent under fluoroscopy guidance for the treatment of chyluria.
  
  
  METHODS
  From December 1999 to July 2006 a total of 40 patients with chyluria were treated by renal pelvic instillation therapy (RPIS). The sclerosing solution was prepared using povidone iodine with contrast agent diluted with sterile water in a ratio of 1:1:3. It was instilled on the side having chylous efflux using a bulb tip ureteric catheter. Unilateral instillation was done in 26 cases, 10 on the right side and 16 on left. Fourteen patients had bilateral chylous efflux and RPIS was performed on both sides in the same session. Fluoroscopy was used to evaluate the complete filling of the pelvic calyceal system. The sclerosing solution was kept in the system for 5 minutes and the ureteric catheter was then withdrawn.
  
  
  RESULTS
  Immediate clearance was observed in 39 patients. Recurrence occurred in five patients. They were treated again using the same procedure with satisfactory results. The longest follow-up was five years and the shortest five months.
  
  
  CONCLUSIONS
  RPIS of chyluria using a single instillation a combination of povidone iodine with contrast agent is safe and effective. Use of fluoroscopy helps to determine the exact amount of sclerosing solution required to completely fill the system and therefore overfilling is avoided. Moreover, the complications, which arise due to pyelointerstitial backflow, are prevented.
authors.affiliation: Chitale Clinic Pvt. Ltd, Solapur, Maharashtra, India. drgrsharma@yahoo.co.in
authors.forename: Gyanendra
authors.initials: G
authors.lastname: Sharma
authors.forename: Vinayak
authors.initials: V
authors.lastname: Chitale
authors.forename: Rajgopal
authors.initials: R
authors.lastname: Karva
authors.forename: Anshu
authors.initials: A
authors.lastname: Sharma
authors.forename: Abdul Bari
authors.initials: AB
authors.lastname: Durug
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002913:Chyle; D004338:Drug Combinations; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D007322:Instillation, Drug; D007682:Kidney Pelvis; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D011206:Povidone-Iodine / Q000008:administration & dosage*; D011704:Pyelonephritis / Q000150:complications; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D016896:Treatment Outcome; D014556:Urine; D014570:Urologic Diseases / Q000175:diagnosis / Q000628:therapy*; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D012597:Sclerosing Solutions; D011206:Povidone-Iodine