Purine and pyrimidine derivatives from the South China Sea gorgonian Subergorgia suberosa.
Three new purine derivatives, namely, 4-caryboxy-5,6-dihydro-4H,8H-pyrimido[1,2,3-cd]purine-8,10(9H)-dione (1), 7,9-dihydro-1-(3-oxobutyl)-1H-purine-6,8-dione (2), and 7-hydro-9-(3-oxobutyl)-1H-purine-6,8-dione (3) together with six known purine and pyrimidine derivatives were isolated from the EtOH/CH(2)Cl(2) extracts of the South China Sea gorgonian Subergorgia suberosa. The structures of 1-3 were determined on the bases of extensive spectroscopic analysis, including 1D and 2D NMR data.
Qi
Shu-Hua
SH
Key Laboratory of Marine Bio-Resourses Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou, Guangdong, PR China. shuhuaqi2001@yahoo.com
Zhang
Si
S
Gao
Cheng-Hai
CH
Li
Qin-Xing
QX
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011687:Purines / Q000737:chemistry / Q000302:isolation & purification*; D011743:Pyrimidines / Q000737:chemistry / Q000302:isolation & purification*
D011687:Purines; D011743:Pyrimidines