Rhodium-catalyzed enantioselective desymmetrization of bicyclic hydrazines with alkynylboronic esters.
The first successful asymmetric transfer of rhodium-alkynyl species to symmetrical strained alkenes has been realized starting from bicyclic hydrazines and alkynylboronic esters.
Crotti
Stefano
S
Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126, Pisa, Italy.
Bertolini
Ferruccio
F
Macchia
Franco
F
Pineschi
Mauro
M
D001897:Boronic Acids / Q000737:chemistry*; D001643:Bridged Bicyclo Compounds / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D001897:Boronic Acids; D001643:Bridged Bicyclo Compounds; D004952:Esters; D006834:Hydrazines; D012238:Rhodium