Natural products in parallel synthesis: triazole libraries of nonactic acid.
The synthesis of a library of nonactic acid-derived triazoloamide derivatives and their evaluation as antimicrobial agents is described.
Luesse
Sarah B
SB
Promiliad Biopharma, 340 W. State Street Athens, OH 45701, USA.
Wells
Gregg
G
Nayek
Abhijit
A
Smith
Adrienne E
AE
Kusche
Brian R
BR
Bergmeier
Stephen C
SC
McMills
Mark C
MC
Priestley
Nigel D
ND
Wright
Dennis L
DL
D000588:Amines; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002384:Catalysis; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D002712:Chlorides / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D015195:Drug Design; D005663:Furans / Q000737:chemistry; D006090:Gram-Negative Bacteria / Q000378:metabolism; D006094:Gram-Positive Bacteria / Q000378:metabolism; D018942:Macrolides / Q000138:chemical synthesis / Q000737:chemistry; D008956:Models, Chemical; D014230:Triazoles / Q000737:chemistry*
D000588:Amines; D000890:Anti-Infective Agents; D002712:Chlorides; D005663:Furans; D018942:Macrolides; D014230:Triazoles; C514123:methyl nonactate; D003300:Copper; C050476:nonactin