title: [Retroperitoneal fibrosis and Castleman disease in two patients with high IgG4 levels].
abstract: With the cumulative increase in the number of autoimmune pancreatitis cases, the disease is now widely accepted as a symptom of IgG4-related systemic disease. We recently experienced two cases of retroperitoneal fibrosis and Castleman disease presenting high IgG4 levels without evident pancreatic lesions. Both patients were successfully treated with steroid therapy. It is necessary to acknowledge that retroperitoneal fibrosis and Castleman disease, with or without pancreatic lesions, may have aspects of IgG4-related systemic disease and that the measurement of serum IgG4 and tissue immunostaining for IgG4 should be considered for diagnosing and treating the conditions.
authors.affiliation: Department of Internal Medicine Gastroenterology, Fujieda City General Hospital.
authors.forename: Ichita
authors.initials: I
authors.lastname: Miwa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Masanobu
authors.initials: M
authors.lastname: Kageoka
authors.forename: Ken
authors.initials: K
authors.lastname: Nagata
authors.forename: Akihiko
authors.initials: A
authors.lastname: Ohata
authors.forename: Yuji
authors.initials: Y
authors.lastname: Noda
authors.forename: Kentarou
authors.initials: K
authors.lastname: Ikeya
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Matsui
authors.forename: Kenji
authors.initials: K
authors.lastname: Koda
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Watanabe
mesh_terms: D000368:Aged; D001327:Autoimmune Diseases / Q000150:complications; D005871:Castleman Disease / Q000150:complications*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012185:Retroperitoneal Fibrosis / Q000150:complications*
chemical_list: D007074:Immunoglobulin G