[Behcet's disease and joint affection].
OBJECTIVE
To study joint pathology in patients with Behcet's disease (BD).


METHODS
The trial enrolled 183 BD patients (128 males, 54females, mean age 32.0 +/- 9.8 years, age at BD onset 22.3 +/- 9.9 years, mean duration of the disease 9.5 +/- 8.9 years.


RESULTS
Joint pathology occurred in 74.8% patients, in 10.9% patients the disease onset was associated with arthritis and arthralgia. 3 patients had aceptic necrosis of the head of the femur and knee joint, 3 patients--bone marrow infarction. Knee joints were affected more frequently than others (up to 40%) followed by ankle, elbow and radiocarpal and other joints. In BD duration about 10 years, none of the examinees had stage III of sacroiliitis, stage II was diagnosed only in 4 patients, stage I (suspicion)--in 9. Significant sacroillitis was not registered, bilateral sacroiliitis occurred only in 9 patients. HLA B5 was detected in 61% patients while HLA B27--only in 9.7%.


CONCLUSIONS
The articular syndrome was seen in 3/4 of BD patients. Arthritis runs a recurrent course. Erosive arthritis, sacroiliitis and combination of the latter with HLA B27 are rare.
Alekberova
Z S
ZS
Elonakov
A V
AV
Goloeva
R G
RG
Smirnov
A V
AV
Guseva
I A
IA
Nasonov
E L
EL
D000328:Adult; D018771:Arthralgia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D001168:Arthritis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis; D012426:Russia / Q000453:epidemiology
D006680:HLA Antigens