[Study on anti-diabetes active fraction and constituents from Potentilla chinesis].
OBJECTIVE
To study the active fraction and constituents from Potentilla chinesis.


METHODS
Tested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.


RESULTS
The fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).


CONCLUSIONS
Fraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.
Zhao
Chuan
C
School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China.
Qiao
Wei
W
Zhang
Yan-Wen
YW
Lu
Bin
B
Duan
Hong-Quan
HQ
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D047309:Flavones; D005419:Flavonoids / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D031987:Potentilla / Q000737:chemistry*
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D047309:Flavones; D005419:Flavonoids; D007004:Hypoglycemic Agents; C043562:flavone