title: Chuktabrins A and B, two novel limonoids from the twigs and leaves of Chukrasia tabularis.
abstract: Two novel limonoids, chuktabrin A (1), featuring the unique motifs of a 1,3-dioxolan-2-one and a 3,4-dihydro-2 H-pyran, and chuktabrin B (2), possessing an unprecedented polycyclic skeleton, were isolated from Chukrasia tabularis. The structures of 1 and 2 bearing a biosynthetically extended C3 and C2 unit at C-15, respectively, were elucidated on the basis of spectroscopic data, and that of 1 was confirmed by a single-crystal X-ray diffraction.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
authors.forename: Chuan-Rui
authors.initials: CR
authors.lastname: Zhang
authors.forename: Cheng-Qi
authors.initials: CQ
authors.lastname: Fan
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Sheng-Ping
authors.initials: SP
authors.lastname: Yang
authors.forename: Yan
authors.initials: Y
authors.lastname: Wu
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Yue
mesh_terms: D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification; D029582:Meliaceae / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D036701:Limonins