title: Strontium levels in different causes of death: diagnostic efficacy in drowning.
abstract: Trace element determination can be applied in forensic medicine to diagnose the cause of death. Drowning is the second leading cause of death from unintentional injury. Despite the many diagnostic methods used, the post-mortem diagnosis of drowning continues to be one of the most difficult in forensic pathology. Strontium is a highly sensitive marker of water aspiration in a liquid medium rich in this metal. The aims of this study were to confirm the diagnostic value of strontium in cases of drowning compared with other causes of death, to analyse factors that could affect its concentration and to ascertain the sensitivity and specificity of strontium in right and left ventricles and peripheral serum for the post-mortem diagnosis of drowning. We studied 120 cadavers selected from medico-legal autopsies with different causes of death. Strontium (Sr) levels were measured in the serum (left and right ventricles and peripheral vein) of all cadavers and, in the case of drowning, in the water medium itself, by using Zeeman AAS. Our results confirm the usefulness of blood Sr levels for diagnosing seawater and freshwater drowning, although great care should be exercised in the latter case.
authors.affiliation: Department of Legal and Forensic Medicine, School of Medicine, University of Murcia, 30100 Espinardo, Murcia, Spain. mdperez@um.es
authors.forename: M D
authors.initials: MD
authors.lastname: Pérez-Cárceles
authors.forename: A
authors.initials: A
authors.lastname: Sibón
authors.forename: M L
authors.initials: ML
authors.lastname: Gil Del Castillo
authors.forename: M A
authors.initials: MA
authors.lastname: Vizcaya
authors.forename: E
authors.initials: E
authors.lastname: Osuna
authors.forename: T
authors.initials: T
authors.lastname: Casas
authors.forename: J L
authors.initials: JL
authors.lastname: Romero
authors.forename: A
authors.initials: A
authors.lastname: Luna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001344:Autopsy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D004332:Drowning / Q000097:blood*; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D005618:Fresh Water; D006801:Humans; D008297:Male; D008875:Middle Aged; D012623:Seawater; D013324:Strontium / Q000097:blood*; D055815:Young Adult
chemical_list: D013324:Strontium