title: [Influence of Qingpeng plaster on blood vessels and mast cells in skin tissue of channel points of nude mice].
abstract: OBJECTIVE
  To investigate the changes in the numbers of blood vessels and mast cells, which is relative to blood microcirculation in skin, during Qingpeng plaster (ZANG medicine) being applied to the skin surface of nude mice.
  
  
  METHODS
  Fifteen healthy adult nude mice were divided into Qingpeng plaster group and the control group. The sites of skin tissues stuck with the plaster or with control plaster were selected after 7 days treated, and then all the slices stained and observed.
  
  
  RESULTS
  The numbers of the vessels and the mast cells increased in the dermal tissue of Qingpeng paster group. Although there were a few dilated blood vessels in the control group, but the numbers of the vessels and the mast cells were obviously less than those of the Qingpeng plaster group. Statistical analysis showed that there was a significant difference (P < 0.001) between tow groups.
  
  
  CONCLUSIONS
  Qingpeng plaster can cause obvious vascular dilatation and promot mast cells aggregation in the Qingpeng plaster stuck parts of the skin tissue.
authors.affiliation: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China. psy_1mf@yahoo.com.cn
authors.forename: Ming-Fu
authors.initials: MF
authors.lastname: Luo
authors.forename: Cui-Hong
authors.initials: CH
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Guo
authors.forename: Jun-Na
authors.initials: JN
authors.lastname: He
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Ma
authors.forename: Shu-You
authors.initials: SY
authors.lastname: Wang
authors.forename: Shun-Yue
authors.initials: SY
authors.lastname: Li
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000166:cytology / Q000187:drug effects*; D002452:Cell Count; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000494:pharmacology*; D005260:Female; D008297:Male; D008407:Mast Cells / Q000166:cytology / Q000187:drug effects*; D051379:Mice; D008819:Mice, Nude; D012867:Skin / Q000098:blood supply / Q000166:cytology* / Q000187:drug effects*
chemical_list: D004365:Drugs, Chinese Herbal; C540321:Qingpeng plaster