First total synthesis of clausine L and pityriazole, a metabolite of the human pathogenic yeast Malassezia furfur.
The first total synthesis of the alkaloid pityriazole is described using three consecutive palladium-catalyzed coupling reactions.
Forke
Ronny
R
Department Chemie, Technische Universität Dresden, Bergstrasse 66, 01069 Dresden, Germany.
Jäger
Anne
A
Knölker
Hans-Joachim
HJ
D002227:Carbazoles / Q000138:chemical synthesis* / Q000378:metabolism; D002384:Catalysis; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000378:metabolism; D008290:Malassezia / Q000378:metabolism*; D010165:Palladium / Q000737:chemistry
D002227:Carbazoles; D007211:Indoles; C531182:clausine L; C531183:pityriazole; D010165:Palladium