Danish-American family (family E) with 'Parkinson's Disease': Pitfalls of genetic studies.
Clinical and genetic investigations were undertaken to evaluate a large Danish-American kindred with a possible autosomal dominant parkinsonian syndrome (PS) as indicated by the index case. After full investigation of available data a suspected autosomal dominant inheritance pattern of PS could not be confirmed. However, it is possible that this kindred represents familial tremor. Longitudinal clinical observations on this family are planned.
Wszolek
Z K
ZK
Department of Internal Medicine, Section of Neurology, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, NE 68198-2045, U.S.A.
Peeiffer
R F
RF
Denson
M A
MA
McComb
R D
RD