Myelodysplastic syndrome with isolated 5q deletion (5q- syndrome). A clonal stem cell disorder characterized by defective ribosome biogenesis.
Cazzola
Mario
M
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism; D002626:Chemistry, Pharmaceutical / Q000379:methods; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D002986:Clinical Trials as Topic; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D000077269:Lenalidomide; D008297:Male; D009190:Myelodysplastic Syndromes / Q000188:drug therapy* / Q000235:genetics*; D013234:Stem Cells / Q000166:cytology; D013577:Syndrome; D013792:Thalidomide / Q000031:analogs & derivatives / Q000627:therapeutic use
D013792:Thalidomide; D000077269:Lenalidomide