title: [Urothelial carcinoma in situ of the seminal vesicles--an indicator of tumour multifocality].
abstract: We report a case of multifocal urothelial carcinoma in situ of the left ureter with early stromal invasion and concomitant in situ lesions in bladder, prostate and seminal vesicle. After complete topographical mapping of the cystoprostatovesiculectomy specimen the unusual manifestation of urothelial carcinoma in situ in a seminal vesicle turned out to be a tumour spread via the ductus ejaculatorius into the seminal vesicle. DNA sequencing of the tumour suppressor gene TP53 of different tumour lesions revealed identical wild-type sequences.
authors.affiliation: Institut für Pathologie der RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen. ngaisa@ukaachen.de
authors.forename: N T
authors.initials: NT
authors.lastname: Gaisa
authors.forename: A
authors.initials: A
authors.lastname: Donner
authors.forename: S
authors.initials: S
authors.lastname: von Serenyi
authors.forename: E
authors.initials: E
authors.lastname: Dahl
authors.forename: J
authors.initials: J
authors.lastname: Grosse
authors.forename: R
authors.initials: R
authors.lastname: Knüchel
mesh_terms: D001706:Biopsy; D002277:Carcinoma / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology; D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D011471:Prostatic Neoplasms / Q000473:pathology; D012669:Seminal Vesicles / Q000473:pathology*; D013050:Spectrometry, Fluorescence