title: Clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension versus three daily injections of ceftiofur sodium sterile powder for the treatment of footrot in feedlot cattle.
abstract: A study was conducted in a feedlot in Alberta, Canada, to compare the clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension with three daily treatments of ceftiofur sodium sterile powder for the treatment of footrot. Use of a long-acting antimicrobial to treat footrot would reduce labor costs and hospital pen space requirements during high-risk periods. Four hundred cattle clinically diagnosed with footrot were systematically randomized to one of two treatment groups. The treatment success rate at 14 days after treatment (99.5% for ceftiofur crystalline free acid sterile injectable suspension and 99.0% for ceftiofur sodium sterile powder for injection) was not statistically different (P>.05) between the two drugs.
authors.affiliation: Alberta Beef Health Solutions Inc., Picture Butte, Alberta, Canada. donkersg@telus.net
authors.forename: Joyce
authors.initials: J
authors.lastname: Van Donkersgoed
authors.forename: Marike
authors.initials: M
authors.lastname: Dussault
authors.forename: Pete
authors.initials: P
authors.lastname: Knight
authors.forename: Les
authors.initials: L
authors.lastname: Byers
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D005260:Female; D005535:Foot Rot / Q000188:drug therapy*; D007794:Lameness, Animal / Q000188:drug therapy; D008297:Male; D016896:Treatment Outcome
chemical_list: D002511:Cephalosporins; C053503:ceftiofur