title: Biomechanical functional and sensory modelling of the gastrointestinal tract.
abstract: The aim of this review is to describe the biomechanical, functional and sensory modelling work that can be used to integrate the physiological, anatomical and medical knowledge of the gastrointestinal (GI) system. The computational modelling in the GI tract was designed, implemented and evaluated using a series of information and communication technologies-based tools. These tools modelled the morphometry, biomechanics, functions and sensory aspects of the human GI tract. The research presented in this review is based on the virtual physiological human concept that pursues a holistic approach to representation of the human body. Such computational modelling combines imaging data, GI physiology, the gut-brain axis, geometrical and biomechanical reconstruction, and computer graphics for mechanical, electronic and pain analysis. The developed modelling will aid research and ensure that medical professionals benefit through the provision of relevant and precise information about a patient's condition. It will also improve the accuracy and efficiency of the medical procedures that could result in reduced cost for diagnosis and treatment.
authors.affiliation: Mech-Sense, Aalborg Hospital Science and Innovation Centre, Søndre Skovvej 15, 9000 Aalborg, Denmark. dliao@hst.aau.dk
authors.forename: Donghua
authors.initials: D
authors.lastname: Liao
authors.forename: Dina
authors.initials: D
authors.lastname: Lelic
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
authors.forename: Asbjørn Mohr
authors.initials: AM
authors.lastname: Drewes
authors.forename: Hans
authors.initials: H
authors.lastname: Gregersen
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena / Q000379:methods*; D003198:Computer Simulation; D041981:Gastrointestinal Tract / Q000294:innervation* / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D012677:Sensation / Q000502:physiology*