title: Panton-Valentine Leukocidin associated with community acquired methicillin resistant Staphylococcus aureus: a case report and review of interim guidelines.
abstract: We report a case of community acquired methicillin resistant Staphylococcus aureus pneumonia. The causative organism was positive for the toxin Panton-Valentine Leukocidin. This resulted in a severe pneumonia requiring a prolonged stay on our intensive care unit. This infection is becoming more common in the United Kingdom. It can cause a far more aggressive illness than the hospital acquired infection with a high mortality if it becomes an invasive infection. The Department of Health has recently produced interim guidelines for its treatment which we have also reviewed.
authors.affiliation: Department of Anaesthetics, Kent and Sussex Hospital, Mount Ephraim, Tunbridge Wells, Kent TN4 9JG, UK. alylowe@aol.com
authors.forename: L N
authors.initials: LN
authors.lastname: Baldwin
authors.forename: A D
authors.initials: AD
authors.lastname: Lowe
mesh_terms: D001427:Bacterial Toxins / Q000032:analysis*; D017714:Community-Acquired Infections / Q000382:microbiology / Q000628:therapy; D005098:Exotoxins / Q000032:analysis*; D005260:Female; D006801:Humans; D007956:Leukocidins / Q000032:analysis*; D016106:Methicillin Resistance; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000382:microbiology* / Q000628:therapy / Q000635:transmission; D017410:Practice Guidelines as Topic; D011379:Prognosis; D013203:Staphylococcal Infections / Q000382:microbiology* / Q000628:therapy / Q000635:transmission; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin