title: Detection of trace Hg2+ via induced circular dichroism of DNA wrapped around single-walled carbon nanotubes.
abstract: The strongly induced circular dichroism (ICD) signals of DNA wrapped around single-walled carbon nanotubes (SWCNTs) are shown by the Synchrotron Radiation Facility. In solution, trace amounts of Hg ions have a strong affinity to bind the nucleic bases of DNA-SWCNTs via a pseudo-first-order kinetic reaction. The Hg binding to the bases of DNA results in partial DNA disassociation from the SWCNTs. Such disassociation of DNA from the SWCNTs will decrease the coupling effects of the transition dipole moments between DNA and SWCNTs, thus inducing the ICD signal of DNA-SWCNTs to decrease significantly. Herein, the ICD of DNA-SWCNTs is applied to detect the concentration of Hg ions at nM level.
authors.affiliation: Laboratory for Bio-Environmental Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Beijing 100049, PR China. gaoxy@ihep.ac.cn
authors.forename: Xueyun
authors.initials: X
authors.lastname: Gao
authors.forename: Gengmei
authors.initials: G
authors.lastname: Xing
authors.forename: Yanlian
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Shi
authors.forename: Ru
authors.initials: R
authors.lastname: Liu
authors.forename: Weiguo
authors.initials: W
authors.lastname: Chu
authors.forename: Long
authors.initials: L
authors.lastname: Jing
authors.forename: Feng
authors.initials: F
authors.lastname: Zhao
authors.forename: Chang
authors.initials: C
authors.lastname: Ye
authors.forename: Hui
authors.initials: H
authors.lastname: Yuan
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Fang
authors.forename: Chen
authors.initials: C
authors.lastname: Wang
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D002413:Cations, Divalent / Q000737:chemistry; D002942:Circular Dichroism / Q000379:methods; D004247:DNA / Q000737:chemistry*; D008628:Mercury / Q000032:analysis / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D037742:Nanotubes, Carbon / Q000737:chemistry*
chemical_list: D002413:Cations, Divalent; D037742:Nanotubes, Carbon; D004247:DNA; D008628:Mercury