title: Dilemma of renal disease in elderly.
abstract: The aging process results in profound anatomic and functional changes in a number of human body systems. Changes in kidney function with normal aging are the most dramatic of any human organ or organ system. These include anatomical, physiological, hemodynamic and immunological changes. Increased propensities of systemic diseases and exposure to poly-pharmacy of the aged group have an additive deleterious effect. The aforementioned changes have its implications on clinical presentations, management and prognosis of all renal diseases in elderly. Atypical presentation, more frequent and longer course are the characteristics of acute renal failure in this age group. Also, presentation of glomerular diseases, clinical course, prognosis, decision of performing a renal biopsy and use of immunosuppressive drugs in elderly specially those subgroup above 80 years of age are still a big challenges that needs a consensus and standardization.
authors.affiliation: Nephrology Unit, New Damietta Al-Azhar University Hospital and Faculty of Medicine, Mansoura Urology and Nephrology Center, Mansoura, Egypt.
authors.forename: Abdel Basset
authors.initials: AB
authors.lastname: El Essawy
authors.forename: Dujanah
authors.initials: D
authors.lastname: Mousa
authors.forename: Mohamed
authors.initials: M
authors.lastname: Al-Sulaiman
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000473:pathology / Q000628:therapy; D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D015432:Glomerulonephritis, Membranoproliferative / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D006417:Hematuria / Q000209:etiology; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017582:Renal Replacement Therapy
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000960:Hypolipidemic Agents; D010975:Platelet Aggregation Inhibitors