A refillable microfabricated drug delivery device for treatment of ocular diseases.
An implantable manually-actuated microfabricated drug delivery device was demonstrated as a new approach for delivering therapeutic compounds to ocular tissue in acute in vitro, ex vivo, and in vivo studies.
Lo
Ronalee
R
Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Li
Po-Ying
PY
Saati
Saloomeh
S
Agrawal
Rajat
R
Humayun
Mark S
MS
Meng
Ellis
E
D004129:Dimethylpolysiloxanes / Q000737:chemistry; D016503:Drug Delivery Systems / Q000295:instrumentation*; D017743:Equipment Reuse; D005123:Eye / Q000473:pathology*; D005128:Eye Diseases / Q000188:drug therapy* / Q000473:pathology; D005240:Feasibility Studies; D006801:Humans; D009339:Needles
D004129:Dimethylpolysiloxanes