Vaccination by muscle electroporation: the injury helps.
Electroporation has been widely adopted in gene therapy and vaccination processes. Improving the vaccination efficiency has been constant question for both basic research and clinical studies. Recent evidences suggest that the EP-induced muscle injury contribute to the high vaccination efficiency by muscle electroporation. Here, we propose increasing the current intensity as a quick and simple approach to improve vaccination efficiency.
Yuan
Ti-Fei
TF
D018274:Electroporation; D006801:Humans; D009132:Muscles; D014611:Vaccination / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage*; D014947:Wounds and Injuries / Q000276:immunology*
D014612:Vaccines