title: A case of canine streptococcal meningoencephalitis diagnosed using universal bacterial polymerase chain reaction assay.
abstract: A 3-year-old, spayed female, mixed-breed dog was evaluated for acute, progressive neurological disease. Analysis of cerebrospinal fluid (CSF) showed neutrophilic pleocytosis. The dog later developed liver disease, thrombocytopenia, and anemia that were presumably secondary to ceftriaxone administration. Bacterial cultures of blood, urine, and CSF were negative. However, a universal bacterial polymerase chain reaction assay of CSF identified deoxyribonucleic acid from Streptococcus spp. The dog recovered with therapy for streptococcal encephalitis.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Street, Columbus, Ohio 43210, USA.
authors.forename: Jeannette S
authors.initials: JS
authors.lastname: Messer
authors.forename: Susan O
authors.initials: SO
authors.lastname: Wagner
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Baumwart
authors.forename: Carmen M
authors.initials: CM
authors.lastname: Colitz
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D004283:Dog Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004285:Dogs; D005260:Female; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D009820:Ohio; D016133:Polymerase Chain Reaction / Q000379:methods / Q000662:veterinary*; D013290:Streptococcal Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D013291:Streptococcus / Q000302:isolation & purification; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents