[The peculiarities of development and course of distal polyneuropathy in diabetes mellitus type I].
A complex clinical and electroneuromyographic study of a representative sample of patients (125 patients aged from 17 to 45 years, mean age 28.5+/-1.0 years, illness duration from the debut to 15 years) with distal polyneuropathy (DP) in diabetes mellitus type I has been carried out. Clinical characteristics of movement and sensory disorders have been compared with electroneuromyographic characteristics in different terms of the disease. The domination of subjective disorders of pain sensitivity in the duration of diabetes mellitus within 3 years, progression of subjective and objective sensory disorders; appearance and progression of reflex and autonomic/trophic disorder in illness duration more than 3 years have been found. The symptoms of DP in diabetes mellitus type I always correspond to the changes of electroneuromyographic parameters; subclinical polyneuropathy diagnosed only on the basis of the electroneuromyographic data emerges in 75% and 45% of patients with diabetes mellitus with illness duration within 3 years and from 3 to 10 years, respectively.
Mitrofanova
I N
IN
Skvortsova
V I
VI
D000293:Adolescent; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D018450:Disease Progression; D004576:Electromyography; D006801:Humans; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology; D011115:Polyneuropathies / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D012720:Severity of Illness Index