title: Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor.
abstract: A fast-scan-rate swept laser for optical coherence tomography (OCT) is suitable to record and analyze a 3-D image volume. However, the whole OCT system speed is limited by data streaming, processing, and storage. In this case, postprocessing is a common technique. Endoscopic clinical applications prefer onsite diagnosis, which requires a real-time technique. Parallel digital signal processors were applied to stream and process data directly from a data digitizer. A real-time system with 20-kHz axial line speed, which was limited only by our swept laser scan rate, was implemented. To couple with the system speed, an endoscope based on an improved 3-D microelectromechanical motor (diameter 1.5 mm, length 9.4 mm) was developed. In vivo 3-D imaging of the human airway was demonstrated.
authors.affiliation: University of California, Irvine, Department of Biomedical Engineering, Irvine, California 92612, USA.
authors.forename: Jianping
authors.initials: J
authors.lastname: Su
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Lingfeng
authors.initials: L
authors.lastname: Yu
authors.forename: Henri
authors.initials: H
authors.lastname: G Colt
authors.forename: Matthew
authors.initials: M
authors.lastname: Brenner
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Chen
mesh_terms: D003199:Computer Systems; D019723:Endoscopes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation*; D008029:Lighting / Q000295:instrumentation; D008168:Lung / Q000033:anatomy & histology*; D019563:Mechanics; D018613:Microscopy, Confocal / Q000295:instrumentation*; D008904:Miniaturization; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D041623:Tomography, Optical Coherence / Q000295:instrumentation*; D014132:Trachea / Q000033:anatomy & histology*