title: Coexistence of left-sided inferior vena cava, deep vein thrombosis of the upper and lower extremities and prothrombotic polymorphisms in a young patient: a case report.
abstract: A literature review suggests an interaction between an anomaly of the inferior vena cava and thrombophilia in the pathogenesis of deep vein thrombosis. Genetic thrombotic abnormalities have been found in some of the subjects having venous thromboembolic diseases. We report a case of a young man presenting with venous thrombosis of the upper and lower extremities, left-sided vena cava inferior and with combination of heterozygosity of the mutation of the genes Methylenetetrahydrofolate reductase 677 and Factor V 1691.
authors.affiliation: aDepartment of Cardiovascular Surgery, Turkey bDepartment of Radiology, Ankara University School of Medicine, Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Sirlak
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cakici
authors.forename: Mustafa Bahadir
authors.initials: MB
authors.lastname: Inan
authors.forename: Sadik
authors.initials: S
authors.lastname: Eryilmaz
authors.forename: Evren
authors.initials: E
authors.lastname: Ustuner
authors.forename: Cetin
authors.initials: C
authors.lastname: Atasoy
authors.forename: Bulent
authors.initials: B
authors.lastname: Kaya
authors.forename: Umit
authors.initials: U
authors.lastname: Ozyurda
mesh_terms: D000328:Adult; D005165:Factor V / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D035002:Lower Extremity; D008297:Male; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP) / Q000235:genetics*; D009154:Mutation; D011110:Polymorphism, Genetic; D034941:Upper Extremity; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000201:enzymology / Q000235:genetics* / Q000473:pathology
chemical_list: D005165:Factor V; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP)