title: Treating sensitive cervical areas with ozone. A prospective controlled clinical trial.
abstract: OBJECTIVE
  To determine whether the treatment of hypersensitive teeth with gaseous ozone (Healozone, KaVo 1600 ppm) for 60 seconds reduces pain immediately after treatment and in the longer term.
  
  
  METHODS
  In three private practices in Switzerland, 31 subjects suffering from hypersensitive teeth were treated with gaseous ozone over a period of 54 weeks (one test and one control tooth in each subject). A cross-over design was chosen. The pain level was measured with a Visual Analogue Scale before and after the treatment.
  
  
  RESULTS
  The subjects' pain level was reduced by 55% +/- 5.5% immediately after the ozone treatment. Over time, the pain level decreased significantly in all groups: The pain level in the test teeth was significantly reduced in Weeks 0-22 (treatment group, P < 0.001) compared to the pain level before treatment. The pain level in the control group was also reduced significantly over time in Weeks 0-22 (no-treatment, P = 0.025) and in Weeks 22-54 (treatment group, P = 0.0065). Comparing test and control teeth over time, there was no statistically significant difference in pain reduction (P = 0.58).
authors.affiliation: Department of Preventive, Restorative and Pediatric Dentistry, School of Dental Medicine, University of Bern, Switzerland.
authors.forename: Jan Eric
authors.initials: JE
authors.lastname: Dähnhardt
authors.forename: Markus
authors.initials: M
authors.lastname: Gygax
authors.forename: Bernhard
authors.initials: B
authors.lastname: Martignoni
authors.forename: Peter
authors.initials: P
authors.lastname: Suter
authors.forename: Adrian
authors.initials: A
authors.lastname: Lussi
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D018592:Cross-Over Studies; D003807:Dentin Sensitivity / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000145:classification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010083:Oxidants, Photochemical / Q000008:administration & dosage / Q000627:therapeutic use*; D010126:Ozone / Q000008:administration & dosage / Q000627:therapeutic use*; D010147:Pain Measurement; D010514:Periodontal Pocket / Q000145:classification; D012907:Smoking; D014100:Toothpastes / Q000627:therapeutic use
chemical_list: D010083:Oxidants, Photochemical; D014100:Toothpastes; D010126:Ozone