A novel HLA-A*3315 allele identified by haplotype-specific extraction and sequence-based typing.
A novel HLA-A*33 variant allele, A*3315, was identified in three Korean siblings. This allele shows only one nucleotide difference from A*330301 in exon 4 at nucleotide position 727 (codon 219 CGG-->TGG), resulting in an amino acid change from arginine (R) to tryptophan (W).
Lim
J
J
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim
Y
Y
Han
K
K
Kim
H-J
HJ
Min
W-S
WS
D000483:Alleles; D001483:Base Sequence; D015234:HLA-A Antigens / Q000235:genetics* / Q000302:isolation & purification; D006239:Haplotypes / Q000235:genetics*; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens; C082945:HLA-A*33 antigen