title: VanB phenotype-vanA genotype Enterococcus faecium with heterogeneous expression of teicoplanin resistance.
abstract: Six VanB phenotype-vanA genotype isolates of Enterococcus faecium with heterogeneous expression of teicoplanin resistance which gave rise to an outbreak at a Korean tertiary care teaching hospital have IS1216V in the coding region of vanS. This could be the underlying cause of the VanB phenotype-vanA genotype with heterogeneous expression of teicoplanin resistance.
authors.affiliation: Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Il Joong
authors.initials: IJ
authors.lastname: Park
authors.forename: Wee Gyo
authors.initials: WG
authors.lastname: Lee
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Kyung Won
authors.initials: KW
authors.lastname: Lee
authors.forename: Gun Jo
authors.initials: GJ
authors.lastname: Woo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D019729:Carbon-Oxygen Ligases / Q000235:genetics; D024881:Drug Resistance, Bacterial; D016984:Enterococcus faecium / Q000235:genetics*; D005798:Genes, Bacterial; D005838:Genotype; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D010641:Phenotype; D017334:Teicoplanin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C071437:VanA ligase, Bacteria; C079913:VanB protein, Enterococcus; D017334:Teicoplanin; D019729:Carbon-Oxygen Ligases