[Molecular biological monitoring for Streptococcus pneumoniae isolated from patients with invasive pneumococcal infection].
Pneumococcal infection is one of the most important problems of the modern medicine. Need for organization of system of epidemiological surveillance for this infection with obligatory assessment of epidemic genovariants by molecular biological methods is evident. Assessment of pneumococci isolated from patients and carriers by using multilocus sequence typing, pulse-field electrophoresis, and restriction fragments length polymorphism analysis allowed to conclude that the latter method, which have high discriminating ability, is advantageous for these purposes.
Martynova
A V
AV
Turkutiukov
V B
VB
D015373:Bacterial Typing Techniques / Q000379:methods*; D016521:Electrophoresis, Gel, Pulsed-Field; D016680:Genome, Bacterial; D006801:Humans; D017720:Molecular Epidemiology; D011008:Pneumococcal Infections / Q000517:prevention & control*; D012150:Polymorphism, Restriction Fragment Length; D017421:Sequence Analysis; D012800:Siberia / Q000453:epidemiology; D013296:Streptococcus pneumoniae / Q000145:classification / Q000235:genetics*