A conserved structure and function of the YidC homologous protein Slr1471 from Synechocystis sp. PCC 6803.
In this article, we show that the orf slr1471 from Synechocystis sp. PCC 6803 codes for a functional member of the YidC/Alb3/Oxa1 protein family, and the encoded protein has a transmembrane topology with a common core structure. Using specific antibodies raised against the Synechocystis YidC homologous protein, we further show that the Synechocystis YidC protein appears to be predominantly localized in the cyanobacterial cytoplasmic membrane. The impact of the described findings for synthesis of membrane proteins and for protein sorting within cyanobacterial cells is discussed.
Sven
Gathmann
G
Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, Albert-Ludwigs-Universität, Stefan-Meier-Strasse 19, Freiburg, Germany.
Eva
Rupprecht
R
Uwe
Kahmann
K
Schneider
Dirk
D
D001426:Bacterial Proteins / Q000737:chemistry*; D002462:Cell Membrane / Q000737:chemistry; D004926:Escherichia coli / Q000737:chemistry / Q000235:genetics; D005816:Genetic Complementation Test; D008565:Membrane Proteins / Q000737:chemistry*; D010957:Plasmids; D017434:Protein Structure, Tertiary; D046939:Synechocystis / Q000737:chemistry* / Q000235:genetics
D001426:Bacterial Proteins; D008565:Membrane Proteins