title: Association of clinical and magnetic resonance imaging findings with outcome in dogs suspected to have ischemic myelopathy: 50 cases (2000-2006).
abstract: OBJECTIVE
  To determine whether clinical signs or magnetic resonance imaging findings were associated with outcome in dogs with presumptive ischemic myelopathy.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  50 dogs.
  
  
  METHODS
  Medical records and magnetic resonance images were reviewed. A neurologic score from 1 (normal) to 5 (most severe degree of dysfunction) was assigned on the basis of neurologic signs at the time of initial examination. Follow-up information was obtained from the medical records and by means of a telephone questionnaire completed by owners and referring veterinarians.
  
  
  RESULTS
  Median neurologic score at the time of initial examination was 3 (range, 2 to 5). Median follow-up time was 584 days (range, 4 to 2,090 days). Neurologic score at the time of initial examination and extent of the lesion seen on magnetic resonance images (quantified as the lesion length-to-vertebral length ratio and as the percentage cross-sectional area of the lesion) were significantly associated with outcome. Sensitivity of using a lesion length-to-vertebral length ratio > 2.0 or a percentage cross-sectional area of the lesion > or = 67% to predict an unsuccessful outcome was 100%.
  
  
  CONCLUSIONS
  Results suggested that severity of neurologic signs at the time of initial examination and extent of the lesions seen on magnetic resonance images were associated with outcome in dogs with ischemic myelopathy.
authors.affiliation: The Centres for Small Animal Studies, Animal Health Trust, Newmarket, Suffolk, England.
authors.forename: Luisa
authors.initials: L
authors.lastname: De Risio
authors.forename: Vicki
authors.initials: V
authors.lastname: Adams
authors.forename: Ruth
authors.initials: R
authors.lastname: Dennis
authors.forename: Fraser J
authors.initials: FJ
authors.lastname: McConnell
authors.forename: Simon R
authors.initials: SR
authors.lastname: Platt
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D004285:Dogs; D005260:Female; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000662:veterinary*; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020760:Spinal Cord Ischemia / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000662:veterinary*