[Photodynamic therapy in vulvar intraepithelial neoplasia].
BACKGROUND
Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).


METHODS
The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).


METHODS
We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva.


CONCLUSIONS
We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree.
Olejek
Anita
A
Katedra i Oddział Kliniczny Ginekologii, Połoznictwa i Ginekologii Onkologicznej SIUM w Bytomiu, Bytom. anitaolejek@wp.pl
Kozak-Darmas
Iwona
I
Biniszkiewicz
Tomasz
T
Kellas-Sleczka
Sylwia
S
Sieroń
Aleksander
A
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000622:Aminolevulinic Acid / Q000008:administration & dosage*; D002278:Carcinoma in Situ / Q000188:drug therapy* / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D011044:Poland; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000473:pathology
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid