title: Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis.
authors.affiliation: Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Nören-Müller
authors.forename: Wolfram
authors.initials: W
authors.lastname: Wilk
authors.forename: Krishna
authors.initials: K
authors.lastname: Saxena
authors.forename: Harald
authors.initials: H
authors.lastname: Schwalbe
authors.forename: Markus
authors.initials: M
authors.lastname: Kaiser
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
mesh_terms: D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000201:enzymology*; D017027:Protein Tyrosine Phosphatases / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
chemical_list: D004791:Enzyme Inhibitors; D007211:Indoles; D017027:Protein Tyrosine Phosphatases