Investigation of Mycobacterium tuberculosis transmission aboard the U.S.S. Ronald Reagan, 2006.
Pulmonary tuberculosis (TB) was diagnosed in a sailor aboard the U.S.S. Ronald Reagan; an investigation was conducted to determine a screening strategy for 1,172 civilian passengers who were aboard during a temporary guest rider program. Sailors were screened for latent TB infection (LTBI) and TB disease. A case-control study was conducted among sailors to determine factors associated with new LTBI. No secondary TB disease was identified; 13% of close contacts had new LTBI. Factors associated with new LTBI among sailors were having been born outside the United States (adjusted odds ratio = 2.80; 95% confidence interval, 1.55--5.07) and being a carrier air wing member (adjusted odds ratio = 2.89; 95% confidence interval, 1.83--4.58). Among 38 civilian passengers berthed near the patient, 1 (3%) had LTBI. The investigation results indicated that Mycobacterium tuberculosis transmission was minimal and eliminated unnecessary TB screening for 1,134 civilians which saved public health resources.
Buff
Ann M
AM
Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, MS E-92, Atlanta, GA 30333, USA.
Deshpande
Swati J
SJ
Harrington
Theresa A
TA
Wofford
Taylor S
TS
O'Hara
Timothy W
TW
Carrigan
Kenichi
K
Martin
Nicholas J
NJ
McDowell
Jackie C
JC
Ijaz
Kashef
K
Jensen
Paul A
PA
Lambert
Lauren A
LA
Moore
Marisa
M
Oeltmann
John E
JE
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D018562:Disease Transmission, Infectious; D006801:Humans; D008297:Male; D008403:Mass Screening; D008499:Medical Records; D008875:Middle Aged; D008889:Military Personnel / Q000706:statistics & numerical data*; D012306:Risk; D012767:Ships / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000635:transmission*; D014481:United States / Q000453:epidemiology