A triumvirate at the testis tip: sharing the power of stem cell control.
Much attention has been given to the role of the niche in controlling stem cell maintenance and differentiation. However, cells other than niche cells might direct stem cell behavior. Evidence from the Drosophila reproductive system suggests that this is the case.
Gilboa
Lilach
L
Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. lilach.gilboa@weizmann.ac.il
D000818:Animals; D002454:Cell Differentiation; D004268:DNA-Binding Proteins / Q000378:metabolism; D004330:Drosophila / Q000166:cytology* / Q000196:embryology / Q000378:metabolism; D029721:Drosophila Proteins / Q000378:metabolism; D004625:Embryo, Nonmammalian; D005854:Germ Cells / Q000166:cytology; D053613:Janus Kinase 1 / Q000378:metabolism; D008297:Male; D008954:Models, Biological; D012097:Repressor Proteins / Q000378:metabolism; D050791:STAT Transcription Factors / Q000378:metabolism; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D013737:Testis / Q000166:cytology / Q000196:embryology / Q000378:metabolism
D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D012097:Repressor Proteins; D050791:STAT Transcription Factors; C081010:zfh1 protein, Drosophila; D053613:Janus Kinase 1