title: Aberrometry in clinical practice: case series.
abstract: The application of aberrometry in the field of refractive surgery has led to the availability of several methods of measuring ocular aberrations in a clinical setting. A case series from four patients diagnosed with corneal thinning disorders is described in this paper (keratectasia following refractive surgery, pellucid marginal degeneration, forme fruste keratoconus or keratoconus). These cases demonstrate how aberrometry can be used to help in the differential diagnosis of patients with corneal thinning disorders, although the standard polynomial fitting for aberrometry data may fail in some patients. Measurement of ocular aberrations can provide an improved description of the optical quality of the eye and hence can be useful to the clinician in evaluating eyes with optical abnormalities.
authors.affiliation: Faculty of Life Sciences, University of Manchester, Manchester M60 1QD, United Kingdom. Hema.Radhakrisnan@manchester.ac.uk
authors.forename: Hema
authors.initials: H
authors.lastname: Radhakrishnan
authors.forename: Clare
authors.initials: C
authors.lastname: O'Donnell
mesh_terms: D000328:Adult; D003261:Contact Lenses; D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis* / Q000628:therapy; D019781:Corneal Topography / Q000379:methods*; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000175:diagnosis* / Q000628:therapy; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects; D008297:Male; D008875:Middle Aged