Coexistence of left-sided inferior vena cava, deep vein thrombosis of the upper and lower extremities and prothrombotic polymorphisms in a young patient: a case report.
A literature review suggests an interaction between an anomaly of the inferior vena cava and thrombophilia in the pathogenesis of deep vein thrombosis. Genetic thrombotic abnormalities have been found in some of the subjects having venous thromboembolic diseases. We report a case of a young man presenting with venous thrombosis of the upper and lower extremities, left-sided vena cava inferior and with combination of heterozygosity of the mutation of the genes Methylenetetrahydrofolate reductase 677 and Factor V 1691.
Sirlak
Mustafa
M
aDepartment of Cardiovascular Surgery, Turkey bDepartment of Radiology, Ankara University School of Medicine, Ankara, Turkey.
Cakici
Mehmet
M
Inan
Mustafa Bahadir
MB
Eryilmaz
Sadik
S
Ustuner
Evren
E
Atasoy
Cetin
C
Kaya
Bulent
B
Ozyurda
Umit
U
D000328:Adult; D005165:Factor V / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D035002:Lower Extremity; D008297:Male; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP) / Q000235:genetics*; D009154:Mutation; D011110:Polymorphism, Genetic; D034941:Upper Extremity; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000201:enzymology / Q000235:genetics* / Q000473:pathology
D005165:Factor V; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP)