Rapid detection of helicobacter pylori by endoscopic brush cytology and comparison with histopathology.
OBJECTIVE
The main objective of this study was to assess antral brush cytology as an alternate approach for the diagnosis of H. pylori infection as compared to histopathology.


METHODS
75 cases with diagnosis of antral gastritis underwent endoscopic antral biopsy as well as antral brushing cytology was included irrespective of age and sex. Cytological slides were stained with Giemsa stain & biopsy slides were stained with H&E and Giemsa stain. Correlation was done between cytological smear slides and biopsy slides.


RESULTS
Among 75 cases, H. pylori were positive in 55 (73.4%) cases of biopsy specimens while in brush cytology it was positive in 48 (64%) cases. In 45 (60%) of 75 cases, H. pylori was seen in both biopsy and brush cytology.


CONCLUSIONS
Endoscopic brush cytology provides an accurate, inexpensive and easy technique in the rapid detection of H.pylori infection.
Akhter
J
J
Department of Patholgy, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu. jasminakhter2003@yahoo.com
Shrestha
H G
HG
D003584:Cytological Techniques / Q000379:methods*; D005260:Female; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D011446:Prospective Studies