Effect of ethanol on opioid drug permeability through caco-2 cell monolayers.
Volpe
Donna A
DA
Division of Product Quality Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, Maryland 20993-0002, USA. donna.volpe@fda.hhs.gov
Asafu-Adjaye
Ebenezer B
EB
Ellison
Christopher D
CD
Doddapaneni
Suresh
S
Uppoor
Ramana S
RS
Khan
Mansoor A
MA
D000701:Analgesics, Opioid / Q000493:pharmacokinetics*; D018938:Caco-2 Cells; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans
D000701:Analgesics, Opioid; D000431:Ethanol