Quality of life and insulin resistance in patients with coronary heart disease.
OBJECTIVE
Diabetes mellitus and impaired glucose tolerance have not only been associated with increased morbidity and mortality, but also with poor quality of life. The purpose of this study was to determine whether there is a relationship between poor quality of life and insulin resistance in patients with myocardial infarction without known diabetes mellitus.


RESULTS
One hundred and nineteen patients, men and women aged between 31 and 80 years with a hospital-diagnosed myocardial infarction occurring 3 months before inclusion, were studied. Minor symptoms evaluation profile was used to estimate the quality of life at entry. Low quality of life (contentment and vitality) was significantly negatively (P<0.05) associated with insulin resistance.


CONCLUSIONS
In patients with coronary heart disease and without known diabetes mellitus an estimated measure of quality of life was significantly and independently associated with poor insulin resistance.
Agewall
Stefan
S
Department of Cardiology, Aker University Hospital, Oslo University, Oslo, Norway. stefan.agewall@medisin.uio.no
Henareh
Loghman
L
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D003327:Coronary Disease / Q000150:complications*; D005260:Female; D006304:Health Status; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications; D008875:Middle Aged; D011581:Psychological Tests; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires; D013548:Sweden