title: Epithelioid hemangioendothelioma of the oral cavity: a case report.
abstract: Epithelioid hemangioendothelioma is a rare vascular neoplasm which exhibits the potential for malignancy and recurrence as well as the ability to metastasize. Although numerous sites of involvement are possible, these tumors most commonly arise in soft tissues, lung, liver, bone, and lymph nodes. In this report, we describe a case of oral epithelioid hemangioendothelioma in a child. This tumor appeared as exophytic ulcerated painless masses in the maxillary and mandibular gingiva. Histologically, the tumor was composed of a proliferation of tumor cells arranged in nests, cords, and short strands. Epithelioid cells exhibited abundant eosinophilic cytoplasm with nuclear and cellular pleomorphism and intra-cytoplasmic vacuoles.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Faculty of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Nooshin
authors.initials: N
authors.lastname: Mohtasham
authors.forename: Ali A H
authors.initials: AA
authors.lastname: Kharrazi
authors.forename: Shokoofeh
authors.initials: S
authors.lastname: Jamshidi
authors.forename: Hamid
authors.initials: H
authors.lastname: Jafarzadeh
mesh_terms: D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D003593:Cytoplasm / Q000648:ultrastructure; D015622:Epithelioid Cells / Q000473:pathology; D005500:Follow-Up Studies; D005887:Gingival Neoplasms / Q000473:pathology*; D018323:Hemangioendothelioma, Epithelioid / Q000473:pathology*; D006801:Humans; D008297:Male; D008334:Mandible; D008437:Maxilla; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D019226:Oral Ulcer / Q000473:pathology; D014617:Vacuoles / Q000648:ultrastructure