Inhibitors of sterol biosynthesis as Staphylococcus aureus antibiotics.
Walsh
Christopher T
CT
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
Fischbach
Michael A
MA
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000378:metabolism; D013211:Staphylococcus aureus / Q000378:metabolism* / Q000472:pathogenicity; D013261:Sterols / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D014774:Virulence
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D013261:Sterols; C091056:CrtM protein, Staphylococcus aureus; D013186:Farnesyl-Diphosphate Farnesyltransferase