VanB phenotype-vanA genotype Enterococcus faecium with heterogeneous expression of teicoplanin resistance.
Six VanB phenotype-vanA genotype isolates of Enterococcus faecium with heterogeneous expression of teicoplanin resistance which gave rise to an outbreak at a Korean tertiary care teaching hospital have IS1216V in the coding region of vanS. This could be the underlying cause of the VanB phenotype-vanA genotype with heterogeneous expression of teicoplanin resistance.
Park
Il Joong
IJ
Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea.
Lee
Wee Gyo
WG
Shin
Jong Hee
JH
Lee
Kyung Won
KW
Woo
Gun Jo
GJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D019729:Carbon-Oxygen Ligases / Q000235:genetics; D024881:Drug Resistance, Bacterial; D016984:Enterococcus faecium / Q000235:genetics*; D005798:Genes, Bacterial; D005838:Genotype; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D010641:Phenotype; D017334:Teicoplanin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C071437:VanA ligase, Bacteria; C079913:VanB protein, Enterococcus; D017334:Teicoplanin; D019729:Carbon-Oxygen Ligases