title: Electron transfer-initiated Diels-Alder cycloadditions of 2'-hydroxychalcones.
abstract: An efficient approach to cyclohexenyl chalcones employing highly electron rich 2'-hydroxychalcone dienophiles via electron transfer-initiated Diels-Alder cycloaddition is described. Using the methodology, the total synthesis of nicolaiodesin C has been accomplished.
authors.affiliation: Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, Boston, Massachusetts 02215, USA.
authors.forename: Huan
authors.initials: H
authors.lastname: Cong
authors.forename: Dustin
authors.initials: D
authors.lastname: Ledbetter
authors.forename: Gerard T
authors.initials: GT
authors.lastname: Rowe
authors.forename: John P
authors.initials: JP
authors.lastname: Caradonna
authors.forename: John A
authors.initials: JA
authors.lastname: Porco
mesh_terms: D000107:Acetylation; D002070:Butadienes / Q000737:chemistry*; D047188:Chalcones / Q000138:chemical synthesis*; D003500:Cyclization; D004583:Electrons
chemical_list: D002070:Butadienes; D047188:Chalcones; C471531:nicolaioidesin C