title: Primary cardiac angiosarcoma evaluated with contrast two-dimensional and real-time three-dimensional echocardiography.
abstract: A 63-year-old lady presented with syncope and atypical chest pain. Conventional two-dimensional (2D) contrast echocardiogram showed a highly vascular mass compressing the right atrium without direct communication. A real-time three-dimensional echocardiogram (RT3DE) revealed its outer spatial relationship with the surrounding structures and its inner heterogeneity as well. A chest computed tomography revealed a solid cardiac mass (6 x 7 cm(2)) arising from the right atrium and multiple pulmonary nodules. Histopathology of the pericardial fluid confirmed angiosarcoma. To our knowledge, this is the first report of histology-confirmed primary cardiac angiosarcoma, which was completely evaluated by conventional 2D, contrast, and RT3DE.
authors.affiliation: Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA.
authors.forename: Hyun Suk
authors.initials: HS
authors.lastname: Yang
authors.forename: Shantanu
authors.initials: S
authors.lastname: Sengupta
authors.forename: Matt M
authors.initials: MM
authors.lastname: Umland
authors.forename: Krishnaswamy
authors.initials: K
authors.lastname: Chandrasekaran
authors.forename: Farouk
authors.initials: F
authors.lastname: Mookadam
mesh_terms: D002637:Chest Pain / Q000209:etiology; D004452:Echocardiography / Q000379:methods*; D019560:Echocardiography, Three-Dimensional; D005260:Female; D006338:Heart Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006394:Hemangiosarcoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D013575:Syncope