Evidence-based recommendations regarding the differential diagnosis and assessment of nasal congestion: using the new GRADE system.
Nasal congestion is an important symptom in nasal pathology and can be defined as an objective restriction of nasal cavity airflow because of mucosal pathology and/or increased mucus secretion (excluding anatomical variants). Using the new Grading Recommendations Assessment, Development and Evaluation system, evidence-based recommendations are made that will encompass different clinical questions regarding diagnostic modalities of nasal congestion: (i) their usefulness in assessment of presence and severity of congestion; (ii) their usefulness in assessment of etiological pathology responsible for congestion; and (iii) their usefulness in follow up and treatment effectiveness evaluation of nasal congestion.
van Spronsen
E
E
Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, the Netherlands.
Ingels
K J A O
KJ
Jansen
A H
AH
Graamans
K
K
Fokkens
W J
WJ
D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006801:Humans; D008487:Medical History Taking; D009093:Mucus / Q000378:metabolism*; D009297:Nasal Mucosa / Q000378:metabolism*; D015508:Nasal Obstruction / Q000175:diagnosis* / Q000503:physiopathology; D009299:Nasal Provocation Tests; D009569:Nitric Oxide / Q000032:analysis; D010808:Physical Examination; D017410:Practice Guidelines as Topic; D012220:Rhinitis / Q000175:diagnosis / Q000503:physiopathology; D025363:Rhinomanometry; D023842:Rhinometry, Acoustic; D012720:Severity of Illness Index
D009569:Nitric Oxide