Nutrient intake risk factors of osteoporosis in postmenopausal women.
This study was conducted to assess the association between dietary nutrient intake and osteoporosis risk in post-menopausal women. Bone mineral density was measured at the lumbar spine by dual-energy X-ray absorptiometry and a structured questionnaire was administered by a trained interviewer, which included information on sociodemographics, medical and reproductive history, and dietary intake. The study sample included 134 osteoporotic and 137 non-osteoporotic subjects between the ages of 52 and 68. Nutrient variables were classified into tertiles. Odds ratios and 95% confidence intervals (CI) were calculated which compared the highest tertile with the lowest tertile as a reference group. Odds ratios for osteoporosis were 1.47 (95% CI: 1.03-2.05) for total protein, 1.62 (95% CI: 0.51-3.92) for animal protein, and 2.98 (95% CI: 1.42-4.23) for sodium. Odds ratios for osteoporosis in the highest tertile were: 0.42 (95% CI: 0.23-0.83) for vegetable protein, 0.72 (95% CI: 0.51-0.90) for Ca, and 0.65 (95% CI: 0.49-0.88) for Fe, relative to the respective lowest tertile. These findings suggest that adequate nutrient intake may be important for prevention of osteoporosis in postmenopausal women.
Kim
Jeongseon
J
Cancer Cohort Branch, National Cancer Control Research Institute, National Cancer Center, 809 Madu1-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea. jskim@ncc.re.kr
Lim
Sun-Young
SY
Kim
Joo-Hak
JH
D015502:Absorptiometry, Photon / Q000379:methods; D000368:Aged; D000375:Aging / Q000502:physiology; D015519:Bone Density / Q000187:drug effects / Q000502:physiology*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D002136:Calcium, Dietary / Q000008:administration & dosage*; D016022:Case-Control Studies; D016001:Confidence Intervals; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D015438:Health Behavior; D006801:Humans; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena / Q000502:physiology*; D016017:Odds Ratio; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology*; D015995:Prevalence; D017584:Reproductive History; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
D050071:Bone Density Conservation Agents; D002136:Calcium, Dietary; D004044:Dietary Proteins