title: [Optimization of matrix formulation of effective parts cataplasm of Pogostemon cablin by uniform design].
abstract: OBJECTIVE
  To optimize the matrix formulation of the effective part Cataplasm of Pogostemon Cablin.
  
  
  METHODS
  The optimal preparation prescription was selected by U17 (17(11)) uniform design,and the tacking strength, cohesive strength and transdermal speed constant were used as test indexes. The equations of three test indexes were established by SPSS. With analysis of the contribution of factors by SPSS regression, the optimal matrix formulation was acquired.
  
  
  RESULTS
  The optimal matrix formulation is carbopol U10-NoveriteTM7s-glycerine-sorbitol-kaolin-citric acid-aluminum trichloride (1.0:5.0:20:2.0:2.0:0.25:0.2).
  
  
  CONCLUSIONS
  The matrix has good adhesive property, proper drug release rate, desirable hemocompatibility with the extractions of Pogostemon cablin.
authors.affiliation: Guang Dong Food and Drug Vocational College, Guangzhou 510520, China. wangxiaogen404@126.com
authors.forename: Xiao-Gen
authors.initials: XG
authors.lastname: Wang
authors.forename: Yu-Fan
authors.initials: YF
authors.lastname: Zou
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Chen
mesh_terms: D000268:Adhesiveness; D001672:Biocompatible Materials / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000378:metabolism; D019686:Lamiaceae / Q000737:chemistry* / Q000378:metabolism; D012044:Regression Analysis; D012869:Skin Absorption; D014835:Volatilization
chemical_list: D001672:Biocompatible Materials; D004365:Drugs, Chinese Herbal