title: Antibiotic prophylaxis before invasive dental procedures in patients with arthroplasties of the hip and knee.
abstract: More than a million hip replacements are carried out each year worldwide, and the number of other artificial joints inserted is also rising, so that infections associated with arthroplasties have become more common. However, there is a paucity of literature on infections due to haematogenous seeding following dental procedures. We reviewed the published literature to establish the current knowledge on this problem and to determine the evidence for routine antibiotic prophylaxis prior to a dental procedure. We found that antimicrobial prophylaxis before dental interventions in patients with artificial joints lacks evidence-based information and thus cannot be universally recommended.
authors.affiliation: University of Geneva Hospitals and Faculty of Medicine, 24 Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.
authors.forename: I
authors.initials: I
authors.lastname: Uçkay
authors.forename: D
authors.initials: D
authors.lastname: Pittet
authors.forename: L
authors.initials: L
authors.lastname: Bernard
authors.forename: D
authors.initials: D
authors.lastname: Lew
authors.forename: A
authors.initials: A
authors.lastname: Perrier
authors.forename: R
authors.initials: R
authors.lastname: Peter
mesh_terms: D019072:Antibiotic Prophylaxis; D016470:Bacteremia / Q000517:prevention & control*; D003729:Dental Care / Q000379:methods*; D017742:Dental Care for Chronically Ill / Q000379:methods; D019317:Evidence-Based Medicine; D017408:Guidelines as Topic; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control*