title: [Clinical and neuroimmunoendocrine effects of doxasosine in treatment of arterial hypertension accompanied by prostate benign hyperplasia in elderly people].
abstract: Arterial hypertension accompanied by prostate benign hyperplasia is very important not medical but social problem in elderly people. The clinical and neuroimmunoendocrine status of elderly patients with arterial hypertension accompanied by prostate benign hyperplasia treated by alpha1-blocker doxasosine is described in the article. Intercellular interactions were examined for tumor necrosis factor alpha, proinflammative interleukine-6, soluble intersellular molecule of adhesion. The positive role of doxasosine is demonstrated.
authors.forename: A N
authors.initials: AN
authors.lastname: Il'nitskiĭ
authors.forename: K I
authors.initials: KI
authors.lastname: Proshchaev
authors.forename: S R
authors.initials: SR
authors.lastname: Filippov
authors.forename: V V
authors.initials: VV
authors.lastname: Liutsko
authors.forename: V V
authors.initials: VV
authors.lastname: Slikin
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D004305:Dose-Response Relationship, Drug; D017292:Doxazosin / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D013997:Time Factors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D014463:Ultrasonography
chemical_list: D000317:Adrenergic alpha-Antagonists; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D018799:Intercellular Adhesion Molecule-1; D017430:Prostate-Specific Antigen; D017292:Doxazosin