TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.
Bowen
D
D
Groves
M J
MJ
Burnett
A K
AK
Patel
Y
Y
Allen
C
C
Green
C
C
Gale
R E
RE
Hills
R
R
Linch
D C
DC
D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000235:genetics*; D009154:Mutation; D015995:Prevalence; D011379:Prognosis; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
D016159:Tumor Suppressor Protein p53