title: BCG osteomyelitis caused by the BCG Tokyo strain and confirmed by molecular method.
abstract: Bacille Calmette-Guérin (BCG) osteitis is a rare complication of BCG vaccination. We describe two cases of BCG osteomyelitis developed in Korean infants who were given multipuncture BCG vaccination. The cultures of bone curettage specimens grew mycobacteria. The isolates were identified as BCG Tokyo strains by the deletion of the region of difference 1 (RD1) and characterization of RD8 and RD14 using the multiplex polymerase chain reaction.
authors.affiliation: Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: So Hee
authors.initials: SH
authors.lastname: Kim
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Kim
authors.forename: Byung Wook
authors.initials: BW
authors.lastname: Eun
authors.forename: Won Joon
authors.initials: WJ
authors.lastname: Yoo
authors.forename: Kyoung Un
authors.initials: KU
authors.lastname: Park
authors.forename: Eun Hwa
authors.initials: EH
authors.lastname: Choi
authors.forename: Eui-Chong
authors.initials: EC
authors.lastname: Kim
authors.forename: Hoan Jong
authors.initials: HJ
authors.lastname: Lee
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D007723:Korea; D008297:Male; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000382:microbiology; D009163:Mycobacterium bovis / Q000235:genetics / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D032581:Tuberculosis Vaccines / Q000009:adverse effects*
chemical_list: D004269:DNA, Bacterial; D032581:Tuberculosis Vaccines