title: Reactive extraction of enantiomers of 1,2-amino alcohols via stereoselective thermodynamic and kinetic processes.
abstract: (R)-amino alcohol with an enantiomeric excess of >95% was resolved by reactive extraction processes from 2 equiv of racemic alcohol using a chiral receptor 2 as an enantioselective extractant. One resolution cycle is composed of three extractions: a stereoselective reversible imine formation, a stereoselective irreversible imine hydrolysis, and the recovery of 2 and enantiomeric amino alcohols.
authors.affiliation: Division of Nano Sciences, Ewha Womans University, Seoul 120-750, South Korea.
authors.forename: Lijun
authors.initials: L
authors.lastname: Tang
authors.forename: Sujung
authors.initials: S
authors.lastname: Choi
authors.forename: Raju
authors.initials: R
authors.lastname: Nandhakumar
authors.forename: Hyunjung
authors.initials: H
authors.lastname: Park
authors.forename: Hyein
authors.initials: H
authors.lastname: Chung
authors.forename: Jik
authors.initials: J
authors.lastname: Chin
authors.forename: Kwan Mook
authors.initials: KM
authors.lastname: Kim
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D000605:Amino Alcohols; D007097:Imines