[Determination of 5-hydroxymethyl furfuraldehyde in different processed products of polygonatum].
OBJECTIVE
By finding the changing regularity of 5-Hydroxymethyl furfuraldehyde (5-HMF) content in Polygonatum for different time, this provides basis for the technology of processing Polygonatum and quality standards of its prepared pieces.


METHODS
The testing solution was acquired by ultrasonic extraction, HPLC was used to determine the contents. The chromatographic conditions: Agilent HC-C18 column (5 microm, 250 mm x 4.6 mm). The mobile phase: methanol-water (15:85) at the flow rate of 1 ml/min. The determination wave length was 284 nm.


RESULTS
All kinds of processed Polygonatum had 5-Hydroxymethyl furfuraldethyde in different degrees, contents in Polygonatum kept relatively stable before 30 hours, but contents rose rapidly after 30 hours, contents decreased as continuing heating.


CONCLUSIONS
The result can provide useful references to quality control and standard porcessing condition of Polygonatum.
Yang
Yun
Y
Henan College of Traditional Chinese Medicine, Zhengzhou, China. yyun@china.com.cn
Xu
Min
M
Feng
Yun-xia
YX
He
Hai-hua
HH
D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000592:standards; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000032:analysis; D006358:Hot Temperature; D010946:Plants, Medicinal / Q000737:chemistry*; D031384:Polygonatum / Q000737:chemistry*; D011786:Quality Control; D012015:Reference Standards; D015203:Reproducibility of Results; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors; D014465:Ultrasonics
D004365:Drugs, Chinese Herbal; C008046:5-hydroxymethylfurfural; D005662:Furaldehyde