An unexpected phosphine-catalyzed [3 + 2] annulation. Synthesis of highly functionalized cyclopentenes.
An unexpected phosphine-catalyzed [3 + 2] annulation from electron-deficient allenes and substituted alkylidenemalononitriles was realized in which the allylic moiety of the substituted alkylidenemalononitriles served as the three carbon unit of the cyclopentenes instead of the electron-deficient allenes.
Lu
Zheng
Z
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Zheng
Suqing
S
Zhang
Xumu
X
Lu
Xiyan
X
D000466:Alkadienes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis*; D009570:Nitriles / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry
D000466:Alkadienes; D003517:Cyclopentanes; D009570:Nitriles; D010720:Phosphines; C025947:propadiene; C044646:phosphine