title: Use of integrated FDG-PET/CT in sarcoidosis.
abstract: We studied five patients with mediastinal lymph node enlargement suggestive of malignant lymphoma, lung cancer, or sarcoidosis. Integrated [(18)F]fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) was performed on all patients. Sarcoidosis can be a pitfall in PET/CT imaging, which may lead to false-positive results of malignancy. Increased FDG uptake in mediastinal lymph nodes is often comparable with malignant lymphoma or lymph node metastases. Histological confirmation of the lesions should be mandatory, except for patients in whom sarcoidosis can be accurately confirmed by other diagnostic methods.
authors.affiliation: Department of Internal Medicine II, University Hospital Ulm, Ulm, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Krüger
authors.forename: Andreas Konrad
authors.initials: AK
authors.lastname: Buck
authors.forename: Felix Manuel
authors.initials: FM
authors.lastname: Mottaghy
authors.forename: Sandra
authors.initials: S
authors.lastname: Pauls
authors.forename: Hubert
authors.initials: H
authors.lastname: Schelzig
authors.forename: Vinzenz
authors.initials: V
authors.lastname: Hombach
authors.forename: Sven Norbert
authors.initials: SN
authors.lastname: Reske
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18