Local effects of inbreeding on embryo number and consequences for genetic diversity in Kerguelen mouflon.
A classical paradigm in population genetics is that homozygosity or inbreeding affects individual fitness through increased disease susceptibility and mortality, and diminished breeding success. Using data from an insular population of mouflon (Ovis aries) founded by a single pair of individuals, we compare embryo number of ewes with different levels of inbreeding. Contrary to expectations, ewes with the highest levels of homozygosity showed the largest number of embryos. Using two different statistical approaches, we showed that this relationship is probably caused by heterozygosity at specific genes. The genetics of embryo number coupled with cyclic dynamics could play a central role in promoting genetic variation in this population.
Kaeuffer
Renaud
R
Département des Sciences Biologiques, Université du Québec à Montréal, CP 8888 succursale centre-ville, Montréal, QC, Canada H3B 3P8. kaeuffer.renaud@courrier.uqam.ca
Réale
Denis
D
Pontier
Dominique
D
Chapuis
Jean-Louis
JL
Coltman
David W
DW
D000818:Animals; D005260:Female; D014644:Genetic Variation; D007178:Inbreeding; D008098:Litter Size; D016015:Logistic Models; D018895:Microsatellite Repeats; D011247:Pregnancy; D034561:Sheep, Domestic / Q000196:embryology / Q000235:genetics*