title: The effect of wood-derived inhibitors on 2, 3-butanediol production by Klebsiella pneumoniae.
abstract: Four potential inhibitors, hydroxymethylfurfural, furfural, syringaldehyde and vanillin, were assayed over a range of concentrations and times to simulate the amounts that might be expected to accumulate when the hydrolyzed water-soluble fraction from steam-treated aspenwood was added in a fed-batch mode to K. pneumoniae. Combinations of the individual materials resulted in a cumulative inhibitory effect. Prolonged incubation could alleviate some of the inhibition.
authors.affiliation: Biotechnology and Chemistry Department, Forintek Canada Corp., 800 Montreal Road, Ottawa, Canada, K1G 3Z5.
authors.forename: N K
authors.initials: NK
authors.lastname: Nishikawa
authors.forename: R
authors.initials: R
authors.lastname: Sutcliffe
authors.forename: J N
authors.initials: JN
authors.lastname: Saddler