Chordate metamorphosis: ancient control by iodothyronines.
A new study shows that iodothyronines induce metamorphosis in the cephalochordate amphioxus by binding to a receptor homologous to vertebrate thyroid hormone receptors. Iodothyronine-induced metamorphosis may be an ancestral feature of the chordates.
Denver
Robert J
RJ
Department of Molecular, Cellular and Developmental Biology, The University of Michigan, Ann Arbor, Michigan 48109-1048, USA. rdenver@umich.edu
D000818:Animals; D002816:Chordata, Nonvertebrate / Q000378:metabolism / Q000502:physiology*; D008675:Metamorphosis, Biological; D011988:Receptors, Thyroid Hormone / Q000378:metabolism*; D013963:Thyroid Hormones / Q000378:metabolism*
D011988:Receptors, Thyroid Hormone; D013963:Thyroid Hormones