title: Ultrasound-estimated bladder weight predicts risk of surgery for benign prostatic hyperplasia in men using alpha-adrenoceptor blocker for LUTS.
abstract: OBJECTIVE
  Although invasive and expensive, the pressure-flow study is known as the reference standard for the diagnosis of bladder outlet obstruction. We investigated the usefulness of ultrasound-estimated bladder weight (UEBW) as a predictor of the need for surgery for benign prostatic hyperplasia (BPH).
  
  
  METHODS
  A total of 97 consecutive male patients >50 years old with lower urinary tract symptoms (LUTS) were prospectively enrolled in this study. The surgery rate was correlated with the UEBW, the results of uroflowmetry, the postvoid residual urine volume, prostate volume, and International Prostate Symptom Score.
  
  
  RESULTS
  Surgery for BPH was performed in 37 of the 97 patients studied. The surgery rate was associated with a high UEBW (>or=35 g), severe LUTS (International Prostate Symptom Score of >or=20), a voided volume of <100 mL at free uroflowmetry, and poor uroflow (maximal flow rate of <10 mL/s). Multivariate analysis revealed that severe LUTS and a high UEBW were the risk factors for surgery for BPH.
  
  
  CONCLUSIONS
  The results of our study have shown that the UEBW can be regarded as a useful parameter to identify patients with LUTS who are at risk of needing surgery for BPH.
authors.affiliation: Department of Urology, University of Fukui Faculty of Medicine, Fukui, Japan. hinaakino@yahoo.co.jp
authors.forename: Hironobu
authors.initials: H
authors.lastname: Akino
authors.forename: Masanobu
authors.initials: M
authors.lastname: Maekawa
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nakai
authors.forename: Rikiya
authors.initials: R
authors.lastname: Shioyama
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Ishida
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Oyama
authors.forename: Yoshiji
authors.initials: Y
authors.lastname: Miwa
authors.forename: Osamu
authors.initials: O
authors.lastname: Yokoyama
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009929:Organ Size; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000601:surgery*; D053448:Prostatism / Q000188:drug therapy* / Q000209:etiology*; D012307:Risk Factors; D014463:Ultrasonography; D001743:Urinary Bladder / Q000000981:diagnostic imaging* / Q000473:pathology*; D013521:Urologic Surgical Procedures, Male / Q000706:statistics & numerical data
chemical_list: D000317:Adrenergic alpha-Antagonists