Revised enzyme synthesis rate expression in cybernetic models of bacterial growth.
A revised enzyme synthesis rate expression for cybernetic models of bacterial growth is presented. The rate expression, which is comprised of inducible and constitutive contributions, provides for a basal enzyme level that is necessary to predict certain types of commonly observed continuous culture transients. The response of a continuous culture to a step change in feed stream composition is simulated using both the old and new formulations, and the ramifications for the "matching-law" formulation are discussed.
Turner
B G
BG
School of Chemical Engineering, Purdue University, West Lafeyette, Indiana 47907, USA.
Ramkrishna
D
D