[Executive dysfunctions in female patients with borderline personality disorder with regard to impulsiveness and depression].
BACKGROUND
Because of the presence of pronounced impulsiveness and affective dysregulation in subjects with Borderline Personality Disorder (BPD) executive dysfunctions have been suspected. Previous studies in this area revealed inconsistent results. However, most of these studies did not control for comorbidity (e. g. impulsiveness, depression) and current medication of participants. The aim of this study was, therefore, to investigate executive (dys)functions in patients with BPD and healthy controls controlling for impulsivity. Furthermore, a second control group with depression was included to test the specificity of the results.


METHODS
24 unmedicated, female BPD patients as well as 24 healthy controls were matched for age, sex, and intelligence. Additionally, 22 female subjects with a life-time diagnosis of depression were included. All subjects completed a neuropsychological test battery assessing executive functions.


RESULTS
No significant differences in executive functioning were found between the three groups. BPD patients showed, however, a decreased ability to delay a gratification compared with controls.


CONCLUSIONS
These results implicate that BPD patients have deficits in motivational areas while other executive functions are not or only marginally involved.
Völker
Kathleen Anna
KA
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Ernst-Moritz-Arndt-Universität Greifswald.
Spitzer
Carsten
C
Limberg
Anke
A
Grabe
Hans-Jörgen
HJ
Freyberger
Harald Jürgen
HJ
Barnow
Sven
S
D000328:Adult; D001883:Borderline Personality Disorder / Q000150:complications / Q000523:psychology*; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000150:complications / Q000523:psychology*; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology*; D055815:Young Adult