title: Early life trauma and sensitivity to current life stressors in individuals with and without cocaine dependence.
abstract: This study investigated the link between exposure to early life trauma, sensitivity to current daily stressors, and cocaine dependence. Individuals with (n = 105) or without (n = 53) cocaine dependence completed the Early Trauma Inventory and the Daily Hassles Scale. In comparison to controls, cocaine-dependent individuals reported almost twice as many daily hassles and perceived those hassles more negatively (p < .001). For participants with cocaine dependence, a significant relationship between exposure to early life trauma and negative perception of current daily hassles was observed (p < .01), whereas no such relationship was observed for participants without cocaine dependence. Adverse childhood events may lead to an altered view of the environment that contributes to increased irritability with daily life events among cocaine-dependent individuals.
authors.affiliation: Division of Clinical Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA. backs@musc.edu
authors.forename: Sudie E
authors.initials: SE
authors.lastname: Back
authors.forename: Kathleen T
authors.initials: KT
authors.lastname: Brady
authors.forename: Angela E
authors.initials: AE
authors.lastname: Waldrop
authors.forename: Sharon D
authors.initials: SD
authors.lastname: Yeatts
authors.forename: Aimee L
authors.initials: AL
authors.lastname: McRae
authors.forename: Eve
authors.initials: E
authors.lastname: Spratt
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D019970:Cocaine-Related Disorders / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D015995:Prevalence; D012680:Sensitivity and Specificity; D013313:Stress Disorders, Post-Traumatic / Q000453:epidemiology* / Q000523:psychology*