title: Efficient array design for sonotherapy.
abstract: New linear multi-row, multi-frequency arrays have been designed, constructed and tested as fully operational ultrasound probes to produce confocal imaging and therapeutic acoustic intensities with a standard commercial ultrasound imaging system. The triple-array probes and imaging system produce high quality B-mode images with a center row imaging array at 5.3 MHz and sufficient acoustic power with dual therapeutic arrays to produce mild hyperthermia at 1.54 MHz. The therapeutic array pair in the first probe design (termed G3) utilizes a high bandwidth and peak pressure, suitable for mechanical therapies. The second multi-array design (termed G4) has a redesigned therapeutic array pair which is optimized for a high time-averaged power output suitable for mild hyperthermia applications. The 'thermal therapy' design produces more than 4 W of acoustic power from the low-frequency arrays with only a 10.5 degrees C internal rise in temperature after 100 s of continuous use with an unmodified conventional imaging system or substantially longer operation at lower acoustic power. The low-frequency arrays in both probe designs were examined and contrasted for real power transfer efficiency with a KLM model which includes all lossy contributions in the power delivery path from system transmitters to the tissue load. Laboratory verification was successfully performed for the KLM-derived estimates of transducer parallel model acoustic resistance and dissipation resistance, which are the critical design factors for acoustic power output and undesired internal heating, respectively.
authors.affiliation: University of California, Davis, CA, USA. dnstephens@ucdavis.edu
authors.forename: Douglas N
authors.initials: DN
authors.lastname: Stephens
authors.forename: Dustin E
authors.initials: DE
authors.lastname: Kruse
authors.forename: Arif S
authors.initials: AS
authors.lastname: Ergun
authors.forename: Stephen
authors.initials: S
authors.lastname: Barnes
authors.forename: X Ming
authors.initials: XM
authors.lastname: Lu
authors.forename: Katherine W
authors.initials: KW
authors.lastname: Ferrara
mesh_terms: D000162:Acoustics; D003198:Computer Simulation; D004560:Electricity; D006361:Heating; D009038:Motion; D015203:Reproducibility of Results; D014159:Transducers; D014464:Ultrasonic Therapy / Q000379:methods*