title: A fluorescence-based fiber optic biosensor for the flow-injection analysis of penicillin.
abstract: A penicillin fiber optic sensor is described. The sensor is based on co-immobilization of a pH indicator, fluorescein isothiocyanate (FITC), and penicillinase on a preactivated biodyne B membrane attached to the end of a bifurcated optical fiber. The characteristics of the sensor are investigated in conjunction with a flow injection analysis system. The proposed sensor is reversible and responds to penicillin in the concentration range of 1 x 10(-4) to 5 x 10(-2) mol/L. The application of this sensor to penicillin analysis in some pharmaceutical samples is demonstrated.
authors.affiliation: Department of Chemistry, University of New Orleans, New Orleans, LA 70148, USA.
authors.forename: X
authors.initials: X
authors.lastname: Xie
authors.forename: A A
authors.initials: AA
authors.lastname: Suleiman
authors.forename: G G
authors.initials: GG
authors.lastname: Guilbault