title: Thrombotic thrombocytopenic purpura associated with multiple myeloma.
abstract: Thrombotic thrombocytopenic purpura is a thrombotic microangiopathic disease. Associations with collagen vascular diseases, pregnancy, some drugs, surgical intervention, and infections are documented (known). Malignancy is also one of the known factors associated with thrombotic thrombocytopenic purpura. These malignancies are usually the disseminated solid organ tumors. Hematological malignancies constitute a rare association. Here, we present a patient with thrombotic thrombocytopenic purpura associated with multiple myeloma and discuss the pathogenesis. To our knowledge, this is the first case report of thrombotic thrombocytopenic purpura associated with multiple myeloma.
authors.affiliation: Department of Internal Medicine, Istanbul Medical School, Istanbul University, Istanbul, Turkey. nalpay@istanbul.edu.tr
authors.forename: Nilufer
authors.initials: N
authors.lastname: Alpay
authors.forename: Sami
authors.initials: S
authors.lastname: Uzun
authors.forename: Gulistan
authors.initials: G
authors.lastname: Bahat
authors.forename: Selim
authors.initials: S
authors.lastname: Yavuz
authors.forename: Nilgun
authors.initials: N
authors.lastname: Erten
authors.forename: Cemil
authors.initials: C
authors.lastname: Tascioglu
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood / Q000150:complications* / Q000473:pathology*; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000150:complications* / Q000473:pathology*