title: Yolk sac tumor in the nasal cavity.
abstract: Yolk sac carcinoma (YST) is rare malignant tumor of germ cell origin. It most commonly arises from the gonads but extragonadal sites of origin are reported in 20% of the cases. Head and neck germ cell tumors are uncommon and only a small number are malignant. We present the case of a 48 years old man presenting with a YST of the sinonasal tract and the arterior skull base. The patient underwent an anterior craniofacial resection and postoperative radiotherapy and continues showing no evidence of disease seven years after treatment. We discuss radiological and histological features of this tumor and provide a review of three other cases of YST arising in children.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Bernardo Cunha Araujo
authors.initials: BC
authors.lastname: Filho
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: McHugh
authors.forename: Ricardo L
authors.initials: RL
authors.lastname: Carrau
authors.forename: Amin B
authors.initials: AB
authors.lastname: Kassam
mesh_terms: D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed