The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial and Hurricane Katrina: lessons for managing clinical trials during and after a natural disaster.
Hurricane Katrina was one of the most catastrophic natural disasters to hit the United States. It had a major impact on health care in New Orleans, LA and the surrounding region, not only in relation to acute illness but also chronic disease. When Hurricane Katrina struck New Orleans on August 29, 2005, there were 193 participants being followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial at Tulane University Health Sciences Center. In the immediate aftermath of the storm, the Tulane University ACCORD Study site, in collaboration with the Study Coordinating Center and the Southeast Clinical Center Network office of the trial at Wake Forest University Health Sciences in North Carolina, took several actions in order to locate the participants, ensure their safety, and maintain the scientific integrity of the trial. We describe the actions taken and the relative success/failure of such actions.
McDuffie
Roberta
R
Tulane University Medical Center, New Orleans, LA, USA.
Summerson
John
J
Reilly
Patricia
P
Blackwell
Caroline
C
Goff
David
D
Kimel
Angela R
AR
Crago
Lenore
L
Fonseca
Vivian
V
D035843:Biomedical Research / Q000379:methods*; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D026661:Clinical Trials Data Monitoring Committees; D002986:Clinical Trials as Topic; D004189:Disaster Planning / Q000379:methods*; D004190:Disasters; D006801:Humans; D008145:Louisiana; D018570:Risk Assessment; D012307:Risk Factors