A comparison of florfenicol and tulathromycine for the treatment of undifferentiated fever in feedlot calves.
The purpose of this study was to compare the relative cost-effectiveness of florfenicol with that of tulathromycin for treatment of undifferentiated fever (UF) in feedlot calves at ultra-high risk of developing UF that receive metaphylactic tulathromycin on arrival at the feedlot. Calves that received therapeutic florfenicol had lower overall mortality (P=.045) and bovine respiratory disease mortality (P=.050) compared with calves that received therapeutic tulathromycin, but no significant differences were detected in feedlot performance, carcass characteristics, or other animal health variables. There was a net advantage of Can$41.19/treated animal in the florfenicol group versus the tulathromycin group. This study demonstrates that it is more cost-effective to use florfenicol than tulathromycin for the initial treatment of UF in feedlot calves at ultra-high risk of developing UF that receive on-arrival metaphylactic tulathromycin.
Perrett
Tye
T
Feedlot Health Management Services Ltd., Okotoks, Alberta, Canada.
Abutarbush
Sameeh M
SM
Wildman
Brian K
BK
Fuchs
Maria T
MT
Schunicht
Oliver C
OC
Pollock
Colleen M
CM
Fenton
R Kent
RK
Jim
G Kee
GK
Guichon
P Timothy
PT
Booker
Calvin W
CW
Berg
Janice
J
Roder
Joe
J
Spire
Mark
M
D000818:Animals; D000831:Animals, Newborn; D000900:Anti-Bacterial Agents / Q000191:economics / Q000627:therapeutic use*; D048090:Bovine Respiratory Disease Complex / Q000188:drug therapy* / Q000401:mortality; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000401:mortality; D003362:Cost-Benefit Analysis; D004187:Disaccharides / Q000191:economics / Q000627:therapeutic use*; D005334:Fever / Q000188:drug therapy / Q000401:mortality / Q000662:veterinary; D006571:Heterocyclic Compounds / Q000191:economics / Q000627:therapeutic use*; D013839:Thiamphenicol / Q000031:analogs & derivatives* / Q000191:economics / Q000627:therapeutic use; D016896:Treatment Outcome; D018942:Macrolides
D000900:Anti-Bacterial Agents; D004187:Disaccharides; D006571:Heterocyclic Compounds; D013839:Thiamphenicol; C035534:florfenicol; C485204:tulathromycin; D018942:Macrolides