Haemolytic disease of the newborn because of rare anti-Vel.
Routine screening for maternal immunization in a 36-year-old woman revealed an alloimmunization against the high-incidence Vel antigen during a second pregnancy. Because of the development of immunoglobulin G-type anti-Vel, the infant developed haemolytic disease of the newborn, with severe jaundice and reticulocytosis. Phototherapy was needed to reduce hyperbilirubinaemia.
van Gammeren
A J
AJ
Department of Clinical Chemistry and Haematology, Amphia Hospital, Breda, The Netherlands. avangammeren@amphia.nl
Overbeeke
M A M
MA
Idema
R N
RN
van Beek
R H T
RH
Ten Kate-Booij
M J
MJ
Ermens
A A M
AA
D000328:Adult; D001789:Blood Group Antigens / Q000276:immunology; D004899:Erythroblastosis, Fetal / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D006932:Hyperbilirubinemia / Q000628:therapy; D007074:Immunoglobulin G; D007231:Infant, Newborn; D007518:Isoantibodies / Q000276:immunology*; D010789:Phototherapy; D011247:Pregnancy
D001789:Blood Group Antigens; D007074:Immunoglobulin G; D007518:Isoantibodies