title: Patient mood and neuropsychological outcome after laparoscopic and conventional colectomy.
abstract: The study was designed to compare patients after laparoscopic and conventional colectomy with regard to early postoperative mood, cognitive function, and neurocognitive variables S100beta and neuron-specific enolase (NSE). Forty-five laparoscopic and 25 open colectomies were enrolled into the prospective study. Outcome measurements were positive and negative postoperative mood (BSKE), neuropsychological tests (Trail-Making Test; word reproduction; Stroop Test), and serum biochemical parameters (S100beta; NSE). Following laparoscopic procedure, patients described significantly better positive mood (P< .05), tended to require less time in the Trail-Making Test and Stroop Test, and had lower postoperative serum concentrations of S100beta compared to conventional colectomy patients (P< .01). The current results revealed several group differences, which, in their entirety, seem to represent a more beneficial outcome after laparoscopic colonic surgery.
authors.affiliation: Department of Anaesthesiology, University of Luebeck, Luebeck, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Gameiro
authors.forename: W
authors.initials: W
authors.lastname: Eichler
authors.forename: O
authors.initials: O
authors.lastname: Schwandner
authors.forename: R
authors.initials: R
authors.lastname: Bouchard
authors.forename: J
authors.initials: J
authors.lastname: Schön
authors.forename: P
authors.initials: P
authors.lastname: Schmucker
authors.forename: H-P
authors.initials: HP
authors.lastname: Bruch
authors.forename: M
authors.initials: M
authors.lastname: Hüppe
mesh_terms: D000339:Affect; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy / Q000379:methods* / Q000523:psychology*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009414:Nerve Growth Factors / Q000097:blood; D010751:Phosphopyruvate Hydratase / Q000097:blood; D011594:Psychometrics; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood
chemical_list: D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase