[Protective and restorative effect of antioxidants in experimental intoxication with chlorophenols].
Experimental studies proved that ortho-chlorophenol intoxication is manifested by increased serum markers of cytolysis (alanine aminotransferase, aspartate aminotransferase) and cholestasis (alkaline phosphatase), intensified lipid peroxidation, depressed activity of antioxidant enzymes (catalase), impaired liver functional state. Studies covered protective efficiency of succinate oxymethyluracil and referent medication mexidol for ortho-chlorophenol poisoning.
Ibatullina
R B
RB
Myshkin
V A
VA
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D002733:Chlorophenols / Q000633:toxicity*; D011041:Poisoning / Q000517:prevention & control*; D051381:Rats
D000975:Antioxidants; D002733:Chlorophenols