title: Multifocal granulomatous hepatitis caused by Actinobacillus pleuropneumoniae serotype 2 in slaughter pigs.
abstract: In a survey of 66 894 slaughter pigs, 11 animals from three farms were found to have multifocal granulomatous lesions in the liver, caused by Actinobacillus pleuropneumoniae serotype 2. The lesions consisted of epithelioid cells and multinucleated giant cells, with asteroid bodies and discernible gram-negative bacteria. Lymph nodes and spleen were occasionally affected. The results suggested that haematogenous spread had occurred from pre-existing pulmonary infections.
authors.affiliation: Toyama Prefectural Meat Inspection Centre, 28-4 Shinbori, Imizu, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ohba
authors.forename: T
authors.initials: T
authors.lastname: Shibahara
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: A
authors.initials: A
authors.lastname: Takashima
authors.forename: M
authors.initials: M
authors.lastname: Nagoshi
authors.forename: R
authors.initials: R
authors.lastname: Osanai
authors.forename: M
authors.initials: M
authors.lastname: Kubo
mesh_terms: D000189:Actinobacillus Infections / Q000473:pathology* / Q000662:veterinary*; D016977:Actinobacillus pleuropneumoniae; D000818:Animals; D006099:Granuloma / Q000382:microbiology / Q000473:pathology; D006520:Hepatitis, Animal / Q000382:microbiology* / Q000473:pathology*; D007150:Immunohistochemistry; D011001:Pleuropneumonia / Q000473:pathology / Q000662:veterinary; D013154:Spleen / Q000473:pathology; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology* / Q000473:pathology*