Non-crystalline and crystalline rheumatic disorders in chronic kidney disease.
Rheumatic syndromes are cause for morbidity in patients with end-stage renal disease. Recent advances in understanding the role of tissue remodeling have provided insight into the pathogenic mechanisms responsible for some of these manifestations. Here, we survey recent and clinically relevant advances in translational research that impact our understanding of rheumatic syndromes seen in patients with significant renal disease. The management of acute and chronic crystalline arthropathies in chronic kidney disease and hemodialysis patients is discussed.
Sarraf
Pasha
P
US National Instituteof Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.
Kay
Jonathan
J
Reginato
Anthony M
AM
D016723:Bone Remodeling; D002129:Calcium Oxalate / Q000378:metabolism; D002805:Chondrocalcinosis / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D003460:Crystallization; D006073:Gout / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D012216:Rheumatic Diseases / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D014511:Uremia / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology
D002129:Calcium Oxalate