title: [Internal fixation of spinal column by posterior approach and extraperitoneal bilateral focal debridement for treatment of tuberculosis of lumbosacral vertebral body].
abstract: OBJECTIVE
  To evaluate the application value of internal fixation of spinal column by posterior approach and extraperitoneal bilateral focal debridement for the treatment of tuberculosis of lumbosacral vertebral body.
  
  
  METHODS
  From March 2000 to February 2005, 16 cases of spinal tuberculosis in L3-S1 were treated with internal fixation of spinal column by posterior approach and extraperitoneal bilateral focal debridement. Sixteen cases included 11 males and 5 females, and the age was 21-56 years. The locations of spinal tuberculosis were L3 in 4 cases, L4 in 6, Ls in 4, and S1 in 2. The course of disease averaged 13 months (range 6 months to 6 years). The ESR of all cases was greater than 20 mm/h (average 40 mm/h); WBC was normal in 14 cases, and a little high in 2 cases. The X-ray picture showed narrow intervertebral space in 5 cases, compressed body of vertebra in 7 cases, and destroyed 2 consecutive vertebra and its sclerotin was conduplicate in 1 case. All cases were abscess in major psoas muscle. The CT showed destruction of bone, abscess-formation and dead bone in body of vertebra of 16 cases. The abscess were found in vertebral canal in 5 cases and dura mater of spinal cord and spinal nerve root crushed in 2 cases. The MRI showed destruction of bone, abscess-formation and hibateral abscess in major psoas muscle in 11 cases. The abscess were found in vertebral canal and dura mater of spinal cord and spinal nerve root crushed in 6 cases. The therapy of paid was treated after operation in all the cases.
  
  
  RESULTS
  Incision healed by first intention in 16 cases; and disruption of wound occurred and healing was achieved after symptomatic treatment in 1 case. Sixteen cases were followed up 2-5 years (29 months on average). Among all the cases, anaesthesia in double thigh was found in 3 cases, adynamia of dorsiflexion in foot in 1 case, gatism in 1 case; after 2 weeks the symptoms were vanished. Indirect hernia of fold inguen were found in 1 case after 2 years, and the patient refused operation for age and was no longer followed up. Fuzzy, ensic and acerb in eyes were found in 6 cases, hearing disturbance were found in 2 cases, and symptoms were vanished after medication adjustment. Low-grade fever and lumbar myalgia were found in 1 case and cured after staying in bed and medication adjustment. All ESR were normal, synostosis of lumbosacral vertebral body was found in 13 cases, kyphosis in 1 case.
  
  
  CONCLUSIONS
  Internal fixation of spinal column by posterior approach and extraperitoneal bilateral focal debridement is safe and available way for the treatment of tuberculosis of lumbosacral vertebral body, it can save the times of operation, shorten period and enhance effect of treatment.
authors.affiliation: Luoyang Orthopaedics and Traumatological Institute, Luoyang Henan, 471002, P.R. China. zhuminghai@china.com.cn
authors.forename: Minghai
authors.initials: M
authors.lastname: Zhu
authors.forename: Guohui
authors.initials: G
authors.lastname: Liang
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Cai
authors.forename: Feng
authors.initials: F
authors.lastname: Feng
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D005592:Fracture Fixation / Q000379:methods*; D005593:Fracture Fixation, Internal; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D012447:Sacrum; D013131:Spine / Q000601:surgery*; D014399:Tuberculosis, Spinal / Q000601:surgery*