title: Generalized essential telangiectasia.
abstract: A 56-year-old woman presented with multiple, erythematous cutaneous vessels that blanched with diascopy and were symmetrically distributed over both lower and upper extremities. The lesions had been present for approximately 6 years and were asymptomatic. Generalized essential telangiectasia (GET) is an idiopathic syndrome of widespread, asymptomatic telangiectases of unknown cause. In our patient, an extensive laboratory evaluation showed low levels of circulating vitamin C as well as the presence of urinary matrix metalloproteinases. The relevance of these abnormal findings is unclear. No uniformly effective treatment exists for GET. Our patient was started on oral doxycycline and was referred for laser therapy.
authors.affiliation: Department of Dermatology, New York University, USA.
authors.forename: Julie K
authors.initials: JK
authors.lastname: Karen
authors.forename: Stephanie J
authors.initials: SJ
authors.lastname: Mengden
authors.forename: Hideko
authors.initials: H
authors.lastname: Kamino
authors.forename: Jerome L
authors.initials: JL
authors.lastname: Shupack
mesh_terms: D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000008:administration & dosage; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D017445:Skin Diseases, Vascular / Q000175:diagnosis* / Q000628:therapy; D013684:Telangiectasis / Q000175:diagnosis* / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline