title: Reliability of death certificates in prostate cancer patients.
abstract: OBJECTIVE
  To evaluate the reliability of cause-of-death diagnoses among prostate cancer patients.
  
  
  METHODS
  Information from death certificates obtained from the Swedish Death Register was compared with systematically reviewed medical records from the population-based Swedish Regional Prostate Cancer Register, South-East Region. In total, 5675 patients were included who had been diagnosed with prostate cancer between 1987 and 1999 and who had died before 1 January 2003.
  
  
  RESULTS
  The proportion of prostate cancer cases classified as having died from prostate cancer was 3% higher in the official death certificates than in the reviewed records [0.03, 95% confidence interval (CI) 0.02 to 0.04]. Overall agreement between the official cause of death and the reviewed data was 86% (95% CI 85 to 87%). A higher accuracy was observed among men with localized disease (88%, 95% CI 87 to 89%), aged 60 years or younger at death (96%, 95% CI 93 to 100%), or who had undergone curative treatment (91%, 95% CI 88 to 95%). This study indicates a relatively high reliability of official cause-of-death statistics of prostate cancer patients in Sweden.
  
  
  CONCLUSIONS
  Mortality data obtained from death certificates may be useful in the evaluation of large-scale prostate cancer intervention programmes, especially among younger patients with localized disease.
authors.affiliation: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. katja.Fall@ki.se
authors.forename: Katja
authors.initials: K
authors.lastname: Fall
authors.forename: Fredrik
authors.initials: F
authors.lastname: Strömberg
authors.forename: Johan
authors.initials: J
authors.lastname: Rosell
authors.forename: Ove
authors.initials: O
authors.lastname: Andrèn
authors.forename: Eberhard
authors.initials: E
authors.lastname: Varenhorst
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D003644:Death Certificates; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000401:mortality*; D012042:Registries; D015203:Reproducibility of Results; D013548:Sweden