[Influence of low magnetic field on lipid peroxidation].
Free radicals (FR) are atoms, molecules or their fragments, whose excess leads to the development of the oxidizing stress, which is the cause of many neoplasmic, neurodegenerative, inflammatory diseases and aging the organism. The main exogenous sources of free radicals are among others: industrial pollution, tobacco smoke, ionizing radiation, ultrasound and magnetic field. The low frequency magnetic field is more and more applied in the physician therapy. The aim of our study was to prove, if the magnetically field applied in the magntetotherapy, affects generating the reactive forms of oxygen according to its working time.


METHODS
The research material made up male, adult, Sprague-Dawley race rats age 3-4 months. To investigation compounds reacting with the tiobarbituric acid, the blood was taken from the rat caudal vein into the test-glass including EDTA before being affected by the magnetic field. After the single exposition and after 14 days of being affected by the magnetic field, the concentration of the compounds reacting with the tiobarbituric acid in the serum was measured.


RESULTS
After the single exposition to the changeable magnetic field (frequency 40 Hz, induction 7 mT, working time 30' and 60 min) the process of the peroxidation of lipids slowed down. A increase of the peroxidation of lipids was observed after 14 days and these changes are statistically significant.


CONCLUSIONS
Low magnetic field used in magnetotherapy causes the changes of the generating the reactive forms of oxygen.
Ciejka
Elzbieta
E
Uniwersytet Medyczny w Łodzi, Katedra Fizjologii Doświadczalnej i Klinicznej, Zakład Fizjologii Układu Krazenia. elzbietareh@interia.pl
Goraca
Anna
A
D000818:Animals; D004574:Electromagnetic Fields / Q000009:adverse effects*; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D017382:Reactive Oxygen Species / Q000528:radiation effects*
D017382:Reactive Oxygen Species