NMR studies of novel Schiff bases derived from L-alpha-amino methyl esters and 3-hydroxypyridin-4-carboxaldehyde.
Schiff bases of 3-hydroxypyridin-4-carboxaldehyde and L-alpha-amino esters as well as those derived from the structurally related amines lacking the ester function have been synthesised. In two cases a tetrahydro-1H-imidazo[4,5-c]pyridine was formed as a by-product. (1)H, (13)C, (15)N-NMR spectral data and density functional theory (DFT) calculations established the structure of all compounds.
Perona
Almudena
A
Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, UNED, Senda del Rey 9, E-28040 Madrid, Spain. aperona@bec.uned.es
Sanz
Dionisia
D
Claramunt
Rosa M
RM
Elguero
José
J
D000596:Amino Acids / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D007555:Isoxazoles / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D008956:Models, Chemical; D015394:Molecular Structure; D012015:Reference Standards; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
D000596:Amino Acids; D004952:Esters; D007555:Isoxazoles; D012545:Schiff Bases