Increase in the frequency of recovery of meticillin-resistant Staphylococcus aureus in acute and chronic maxillary sinusitis.
This study compared the rate of recovery of meticillin-resistant Staphylococcus aureus (MRSA) between the periods 2001-2003 and 2004-2006 in acute and chronic maxillary sinusitis. Cultures were obtained from 458 patients, 244 with acute and 214 with chronic maxillary sinusitis; 215 isolates were recovered in the 2 years between 2001 and 2003 (118 from acute and 97 from chronic sinusitis), and 243 in the 2 years between 2004 and 2006 (126 from acute and 117 from chronic sinusitis). S. aureus was isolated from ten (8 %) of the patients with acute sinusitis between 2001 and 2003, three (30 %) of which were MRSA, and from 13 (10 %) of the patients with acute sinusitis between 2004 and 2006, nine (69 %) of which were MRSA (P <0.01). S. aureus was found in 15 (15 %) of the patients with chronic sinusitis between 2001 and 2003, four (27 %) of which were MRSA, and from 23 (20 %) of the patients with chronic sinusitis between 2004 and 2006, 14 (61 %) of which were MRSA (P <0.05). Antimicrobial therapy was administered over the last 3 months to 122 (57 %) of the patients with chronic sinusitis. MRSA was isolated more often from these individuals (28/122; 23 %) than from those not treated previously (10/92 or 11 %) (P <0.05). These data illustrate that a significant increase occurred in the rate of recovery of MRSA in patients with acute and chronic maxillary sinusitis over the periods studied.
Brook
Itzhak
I
Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA.
Foote
Perry A
PA
Departments of Otolaryngology, Alachua General and North Florida Regional Hospitals, Gainesville, FL, USA.
Hausfeld
Jeffrey N
JN
Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D006801:Humans; D015523:Maxillary Sinusitis / Q000188:drug therapy / Q000382:microbiology*; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance; D008875:Middle Aged; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000187:drug effects*
D008712:Methicillin