title: Seborrheic dermatitis flare in a Dutch male due to commensal Malassezia furfur overgrowth.
abstract: This is a case of seborrheic dermatitis (SD) barbae from which Malassezia furfur (M. furfur) was isolated. The patient was a 57-year-old Dutch male, who was hospitalized for fever and weakness of extremities. He presented with symmetrical erythema with an abundance of greasy chaffy scales on his beard area. No reasons were detected for his fever following a routine search. M. furfur was identified through mycological examination, including direct microscopic examination, culture, Tween test, esculine splitting test and DNA sequencing, of samples from the skin lesions. The patient was treated with oral itraconazole capsules (200 mg, b.i.d. for 8 days, then 200 mg o.d. for 13 days), washing his scalp and face with 2% ketoconazole shampoo (once a day) and topical application of a cream containing 1% naftifine hydrochloride and 0.25% ketoconazole (b.i.d.). After treatment the fever subsided and the SD lesion gradually healed. M. furfur was not isolated again from skin scrapings and 7 days later therapy was terminated and no recurrence was noted after one week follow-up since the cessation of treatment.
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, P. R. China. ranyuping@vip.sina.com
authors.forename: Yuping
authors.initials: Y
authors.lastname: Ran
authors.forename: Xiaodan
authors.initials: X
authors.lastname: He
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.forename: Yaling
authors.initials: Y
authors.lastname: Dai
authors.forename: Lina
authors.initials: L
authors.lastname: Li
authors.forename: G S
authors.initials: GS
authors.lastname: Bulmer
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D012628:Dermatitis, Seborrheic / Q000188:drug therapy / Q000382:microbiology*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D005145:Face / Q000382:microbiology*; D006801:Humans; D008290:Malassezia / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D044465:White People
chemical_list: D000935:Antifungal Agents