Brown-Séquard syndrome secondary to spontaneous bleed from postradiation cavernous angiomas.
The spontaneous occurrence of acute Brown-Séquard syndrome is an extremely rare event, with most reported cases being secondary to spontaneous epidural hematomas and spinal cord ischemia. We report a rare case of Brown-Séquard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood. Postulated mechanisms leading to the condition include postradiation molecular changes and venous occlusion.
Mathews
M S
MS
Department of Neurological Surgery, University of California Irvine, Irvine, Calif, USA. mmathews@uci.edu
Peck
W W
WW
Brant-Zawadzki
M
M
D000328:Adult; D018437:Brown-Sequard Syndrome / Q000175:diagnosis* / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000209:etiology*; D006392:Hemangioma, Cavernous / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000150:complications* / Q000175:diagnosis; D011878:Radiotherapy / Q000009:adverse effects*