Carbocyclic Sinefungin.
(3aS,4S,6R,6aR)-Tetrahydro-2,2-dimethyl-6-vinyl-3aH-cyclopenta[d][1,3]-dioxol-4-ol, itself available from ribose, provided a convenient entry point for an 18-step preparation of carbocyclic sinefungin. This procedure is adaptable to a number of carbocyclic sinefungin analogs with diversity of heterocyclic base and in the amino acid bearing side chain.
Yin
Xueqiang
X
Department of Chemistry and Biochemistry, Auburn University Auburn, Alabama 36849-5312.
Zhao
Guoxia
G
Schneller
Stewart W
SW