title: Efficient synthesis of sulfonyl azides from sulfonamides.
abstract: Triflyl azide serves as an efficient diazo transfer reagent in this first direct synthesis of sulfonyl azides from readily available and stable sulfonamides. The process is experimentally simple, mild, and high-yielding. Sulfonyl azides participate in various catalytic transformations providing rapid access to diversely functionalized sulfonamide derivatives in good yields.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Raushel
authors.forename: Suresh M
authors.initials: SM
authors.lastname: Pitram
authors.forename: Valery V
authors.initials: VV
authors.lastname: Fokin
mesh_terms: D001386:Azides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D013449:Sulfonamides / Q000737:chemistry*; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001386:Azides; D013449:Sulfonamides; D013450:Sulfones