title: Consortium to Establish a Registry for Alzheimer's Disease (CERAD): the first twenty years.
abstract: The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) was funded by the National Institute on Aging in 1986 to develop standardized, validated measures for the assessment of Alzheimer's disease (AD). The present report describes the measures that CERAD developed during its first decade and their continued use in their original and translated forms. These measures include clinical, neuropsychological, neuropathologic, and behavioral assessments of AD and also assessment of family history and parkinsonism in AD. An approach to evaluating neuroimages did not meet the standards desired. Further evaluations that could not be completed because of lack of funding (but where some materials are available) include evaluation of very severe AD and of service use and need by patient and caregiver. The information that was developed in the U.S. and abroad permits standardized assessment of AD in clinical practice, facilitates epidemiologic studies, and provides information valuable for individual and public health planning. CERAD materials and data remain available for those wishing to use them.
authors.affiliation: Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, USA. ggf@geri.duke.edu
authors.forename: Gerda G
authors.initials: GG
authors.lastname: Fillenbaum
authors.forename: Gerald
authors.initials: G
authors.lastname: van Belle
authors.forename: John C
authors.initials: JC
authors.lastname: Morris
authors.forename: Richard C
authors.initials: RC
authors.lastname: Mohs
authors.forename: Suzanne S
authors.initials: SS
authors.lastname: Mirra
authors.forename: Patricia C
authors.initials: PC
authors.lastname: Davis
authors.forename: Pierre N
authors.initials: PN
authors.lastname: Tariot
authors.forename: Jeremy M
authors.initials: JM
authors.lastname: Silverman
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Clark
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Welsh-Bohmer
authors.forename: Albert
authors.initials: A
authors.lastname: Heyman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000503:physiopathology; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D012042:Registries; D012958:Societies, Scientific / Q000458:organization & administration*