Intraoperative imaging of pancreas transplant allografts using indocyanine green with laser fluorescence.
Vascular thrombosis is a cause of allograft loss after pancreas transplantation. We present the use of intraoperative fluorescence imaging with the SPY imaging device (Novadaq Technologies Inc, Toronto, Canada) in two pancreas transplants as a means to assess potency of the vascular anastomoses. Intravenous indocyanine green 2.5 mg/mL was fluoresced with the device to create the intraoperative video sequences, which were recorded. After 60-day follow-up, real-time SPY imaging on these two pancreas transplants did not demonstrate adverse effects on patients or the transplanted allografts. This method of vascular imaging could prove useful in improving short-term graft survival and possibly lowering the thrombosis rates seen with pancreas transplantation. Long-term correlation studies between intraoperative findings and graft survival must be performed to confirm the utility of this imaging method.
Sanchez
Edmund Q
EQ
Baylor Regional Transplant Institute, Baylor University Medical Center, Dallas, Texas, USA. edmunds@BaylorHealth.edu
Chinnakotla
Srinath
S
Khan
Tariq
T
Nikitin
Dmitriy
D
Vasani
Sugam
S
Randall
Henry B
HB
McKenna
Greg J
GJ
Ruiz
Richard
R
Onaca
Nicholas
N
Levy
Marlon F
MF
Goldstein
Robert M
RM
Docherty
John C
JC
Hurd
David K
DK
Klintmalm
Göran B
GB