Genomics and ethics: the case of cloned and/or transgenic animals.
The point of the present study is to illustrate and, if possible, promote the existing link between genomics and ethics, taking the example of cloned and transgenic animals. These 'new animals' raise theoretical and practical problems that concern applied ethics. We will explore more particularly an original strategy showing that it is possible, starting from philosophical questioning about the nature of identity, to use a genomic approach, based on amplification fragment length polymorphism (AFLP) and methylation-sensitive amplification polymorphism (MSAP) detection, to provide useful tools to define more rigorously what cloned animals are, by testing their genetic and epigenetic identity. We expect from the future results of this combined approach to stimulate the creativity of the philosophical and ethical reflection about the impact of biotechnology on animals, and to increase scientific involvement in such issues.
de Montera
Béatrice
B
Laboratoire de Biologie du Développement et Biotechnologies, INRA, Domaine de Vilvert, 78 352 Jouy-en-Josas cedex, France. bdemontera@tiscali.fr