title: HIV and obstetric complications and fetal outcomes in Vellore, India.
abstract: Antenatal prevalence is more than 1% in parts of India, yet little is known about the complications and fetal outcomes in this region. We reviewed the records of 23,386 women who delivered at the Christian Medical College Hospital in Vellore, India from 2000 through 2002. HIV-infected women were more likely than HIV-uninfected women to have pregnancy-induced hypertension, anaemia, breech presentations, stillborn babies and fetal deaths. HIV-infected women who did not receive mother-to-child transmission prophylaxis or had breech fetal presentation were more likely to have fetal deaths (P = 0.001). HIV prophylaxis and optimal prenatal care should be a priority for HIV-infected pregnant women in resource-limited countries.
authors.affiliation: Department of Obstetrics and Gynaecology, Christian Medical College, Vellore, India. jessielionel@cmcvellore.ac.in
authors.forename: Jessie
authors.initials: J
authors.lastname: Lionel
authors.forename: T K
authors.initials: TK
authors.lastname: Aleyamma
authors.forename: Lilly
authors.initials: L
authors.lastname: Varghese
authors.forename: Jessica
authors.initials: J
authors.lastname: Buck
authors.forename: Geetha
authors.initials: G
authors.lastname: Gopalakrishnan
authors.forename: Sreekanth
authors.initials: S
authors.lastname: Chaguturu
authors.forename: Susan
authors.initials: S
authors.lastname: Cu-Uvin
authors.forename: Kenneth
authors.initials: K
authors.lastname: Mayer
mesh_terms: D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000517:prevention & control / Q000635:transmission / Q000821:virology; D018023:HIV Seronegativity; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008485:Medical Audit; D019829:Nevirapine / Q000627:therapeutic use; D007744:Obstetric Labor Complications / Q000453:epidemiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011295:Prenatal Care; D015215:Zidovudine / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D015215:Zidovudine; D019829:Nevirapine