Severe acute haemorrhagic liver failure in a neonate with a favourable spontaneous outcome.
Acute liver failure in neonates is rare and is frequently associated with an unfavourable outcome. There is no curative treatment other than liver transplantation. Screening for viral, metabolic, toxic or vascular disease is essential to assess the prognosis and to guide specific treatment. Hepatic haemorrhage in neonates is often associated with bacterial infection, trauma and coagulopathies. We present a unique case of neonatal acute liver failure and multifocal massive haemorrhagic intrahepatic lesions of traumatic origin, documented by US and MRI. The patient made a spontaneous recovery. Clinical, biological and imaging outcome was excellent despite the apparent severity of the initial features. The only possible aetiology was a difficult caesarean delivery for mild fetal macrosomia.
Cavet
Madeleine
M
Service de Radiologie, Hôpital d'enfants Armand-Trousseau, Université Pierre et Marie Curie Paris VI, 26-28 Avenue du docteur Arnold Netter, 75571, Paris Cedex 12, France.
Balu
Marie
M
Garel
Catherine
C
Mitanchez
Delphine
D
Renolleau
Sylvain
S
Alexandre
Marie
M
Pariente
Danièle
D
Ducou le Pointe
Hubert
H
D006470:Hemorrhage / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D008107:Liver Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D017114:Liver Failure, Acute / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D012075:Remission, Spontaneous; D014463:Ultrasonography