title: Cucurbitane-type triterpenoids from the stems of momordica charantia.
abstract: Four new cucurbitane-type triterpenes, cucurbita-5,23(E)-diene-3beta,7beta,25-triol (1), 3beta-acetoxy-7beta-methoxycucurbita-5,23(E)-dien-25-ol (2), cucurbita-5(10),6,23(E)-triene-3beta,25-diol (5), and cucurbita-5,24-diene-3,7,23-trione (6), together with four known triterpenes, 3beta,25-dihydroxy-7beta-methoxycucurbita-5,23(E)-diene (3), 3beta-hydroxy-7beta,25-dimethoxycucurbita-5,23(E)-diene (4), 3beta,7beta,25-trihydroxycucurbita-5,23(E)-dien-19-al (7), and 25-methoxy-3beta,7beta-dihydroxycucurbita-5,23(E)-dien-19-al (8), were isolated from the methyl alcohol extract of the stems of Momordica charantia. The structures of the new compounds were elucidated by spectroscopic methods.
authors.affiliation: Graduate Institute of Biotechnology, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan, Republic of China.
authors.forename: Chi-I
authors.initials: CI
authors.lastname: Chang
authors.forename: Chiy-Rong
authors.initials: CR
authors.lastname: Chen
authors.forename: Yun-Wen
authors.initials: YW
authors.lastname: Liao
authors.forename: Hsueh-Ling
authors.initials: HL
authors.lastname: Cheng
authors.forename: Yo-Chia
authors.initials: YC
authors.lastname: Chen
authors.forename: Chang-Hung
authors.initials: CH
authors.lastname: Chou
mesh_terms: D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D029777:Momordica charantia / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane