title: Abnormal fundus autofluorescence patterns in myopic choroidal neovascularisation.
abstract: OBJECTIVE
  To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularisation (CNV).
  
  
  METHODS
  Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. FAF patterns, time after the onset of CNV seen on FAF and FAF changes were evaluated.
  
  
  RESULTS
  The following patterns were observed: pattern I (n = 2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n = 11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n = 4), large lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n = 10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on colour fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, nine eyes; pattern III, two eyes).
  
  
  CONCLUSIONS
  Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV.
authors.affiliation: Department of Ophthalmology, Osaka University Medical School, Osaka, Japan. sawamiki@ophthal.med.osaka-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Sawa
authors.forename: F
authors.initials: F
authors.lastname: Gomi
authors.forename: M
authors.initials: M
authors.lastname: Tsujikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ikuno
authors.forename: H
authors.initials: H
authors.lastname: Sakaguchi
authors.forename: K
authors.initials: K
authors.lastname: Sayanagi
authors.forename: Y
authors.initials: Y
authors.lastname: Tano
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D020256:Choroidal Neovascularization / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000473:pathology*; D009896:Optic Atrophy / Q000175:diagnosis*; D012189:Retrospective Studies