title: Intraoperative imaging of pancreas transplant allografts using indocyanine green with laser fluorescence.
abstract: Vascular thrombosis is a cause of allograft loss after pancreas transplantation. We present the use of intraoperative fluorescence imaging with the SPY imaging device (Novadaq Technologies Inc, Toronto, Canada) in two pancreas transplants as a means to assess potency of the vascular anastomoses. Intravenous indocyanine green 2.5 mg/mL was fluoresced with the device to create the intraoperative video sequences, which were recorded. After 60-day follow-up, real-time SPY imaging on these two pancreas transplants did not demonstrate adverse effects on patients or the transplanted allografts. This method of vascular imaging could prove useful in improving short-term graft survival and possibly lowering the thrombosis rates seen with pancreas transplantation. Long-term correlation studies between intraoperative findings and graft survival must be performed to confirm the utility of this imaging method.
authors.affiliation: Baylor Regional Transplant Institute, Baylor University Medical Center, Dallas, Texas, USA. edmunds@BaylorHealth.edu
authors.forename: Edmund Q
authors.initials: EQ
authors.lastname: Sanchez
authors.forename: Srinath
authors.initials: S
authors.lastname: Chinnakotla
authors.forename: Tariq
authors.initials: T
authors.lastname: Khan
authors.forename: Dmitriy
authors.initials: D
authors.lastname: Nikitin
authors.forename: Sugam
authors.initials: S
authors.lastname: Vasani
authors.forename: Henry B
authors.initials: HB
authors.lastname: Randall
authors.forename: Greg J
authors.initials: GJ
authors.lastname: McKenna
authors.forename: Richard
authors.initials: R
authors.lastname: Ruiz
authors.forename: Nicholas
authors.initials: N
authors.lastname: Onaca
authors.forename: Marlon F
authors.initials: MF
authors.lastname: Levy
authors.forename: Robert M
authors.initials: RM
authors.lastname: Goldstein
authors.forename: John C
authors.initials: JC
authors.lastname: Docherty
authors.forename: David K
authors.initials: DK
authors.lastname: Hurd
authors.forename: Göran B
authors.initials: GB
authors.lastname: Klintmalm