title: A hybrid plasmonic-photonic nanodevice for label-free detection of a few molecules.
abstract: Noble metal nanowaveguides supporting plasmon polariton modes are able to localize the optical fields at nanometer level for high sensitivity biochemical sensing devices. Here we report on the design and fabrication of a novel photonic-plasmonic device which demonstrates label-free detection capabilities on single inorganic nanoparticles and on monolayers of organic compounds. In any case, we determine the Raman scattering signal enhancement and the device detection limits that reach a number of molecules between 10 and 250. The device can be straightforwardly integrated in a scanning probe apparatus with the possibility to match topographic and label-free spectroscopic information in a wide range of geometries.
authors.affiliation: BIONEM laboratory, University of Magna Graecia, Campus S. Venuta, Catanzaro, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: De Angelis
authors.forename: Maddalena
authors.initials: M
authors.lastname: Patrini
authors.forename: Gobind
authors.initials: G
authors.lastname: Das
authors.forename: Ivan
authors.initials: I
authors.lastname: Maksymov
authors.forename: Matteo
authors.initials: M
authors.lastname: Galli
authors.forename: Luca
authors.initials: L
authors.lastname: Businaro
authors.forename: Lucio Claudio
authors.initials: LC
authors.lastname: Andreani
authors.forename: Enzo
authors.initials: E
authors.lastname: Di Fabrizio
mesh_terms: D008855:Microscopy, Electron, Scanning; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D010087:Oxides / Q000737:chemistry; D017655:Silicon Compounds / Q000737:chemistry; D013059:Spectrum Analysis, Raman
chemical_list: D010087:Oxides; D017655:Silicon Compounds