title: Role of magnetic resonance methods in the evaluation of prostate cancer: an Indian perspective.
abstract: The challenges in detection, localization, and staging of prostate cancer have prompted the investigation of the role of various magnetic resonance (MR) methodologies in a large cohort of men prior to biopsy. The identification of suspicious areas of malignancy was carried out using magnetic resonance imaging (MRI), magnetic resonance spectroscopic imaging (MRSI) and diffusion-weighted imaging (DWI). Our data shows that apparent diffusion coefficient (ADC) may be a reliable marker to differentiate normal, benign, and malignant prostate tissues similar to the metabolite ratio. Also, the combined use of MRSI and DWI improves the diagnosis of prostate cancer. In this review, we present our experience on the use of MRI, MRSI and DWI methods in the assessment of prostate cancer in Indian men. Further, analysis of the comparison of the ADC and the metabolite ratio values reported in the literature across various patient populations are presented.
authors.affiliation: Department of NMR, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. jagan1954@hotmail.com
authors.forename: Naranamangalam R
authors.initials: NR
authors.lastname: Jagannathan
authors.forename: Virendra
authors.initials: V
authors.lastname: Kumar
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kumar
authors.forename: Sanjay
authors.initials: S
authors.lastname: Thulkar
mesh_terms: D006801:Humans; D007194:India; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011467:Prostate / Q000033:anatomy & histology / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology*; D012016:Reference Values
chemical_list: D017430:Prostate-Specific Antigen