Peroxisomes: minted by the ER.
Peroxisomes are one of numerous organelles in a eukaryotic cell; they are small, single-membrane-bound vesicles involved in cellular metabolism, particularly fatty acid degradation. Transport of metabolites and co-factors in and across the membrane is taken care of by specific transporters. Peroxisome formation and maintenance has been debated for a long time: opinions swinging from autonomous to ER-derived organelles. Only recently it has been established firmly that the site of origin of peroxisomes is the ER. It implies that a new branch of the endomembrane system is open to further characterization.
Tabak
Henk F
HF
Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. h.f.tabak@uu.nl
van der Zand
Adabella
A
Braakman
Ineke
I
D000818:Animals; D004721:Endoplasmic Reticulum / Q000502:physiology*; D006801:Humans; D020675:Peroxisomes / Q000502:physiology*