title: Single-step apical barrier placement in immature teeth using mineral trioxide aggregate and management of periapical inflammatory lesion using platelet-rich plasma and hydroxyapatite.
abstract: We present here a case report of a tooth with an immature root with a large periapical lesion. The open apex was managed by placing an apical barrier using mineral trioxide aggregate, and the periapical lesion was treated surgically. A combination of platelet-rich plasma (PRP) and hydroxyapatite graft (HA) was used to achieve faster healing of the periapical lesion. The case was followed up for 11 months. The indications and advantages of apical barrier placement, periapical surgery, and the role of PRP and HA in postsurgical healing are discussed.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Rural Dental College, Rahata, Ahmednagar, India.
authors.forename: Hemalatha
authors.initials: H
authors.lastname: Hiremath
authors.forename: Neerav
authors.initials: N
authors.lastname: Gada
authors.forename: Yogesh
authors.initials: Y
authors.lastname: Kini
authors.forename: Sadanand
authors.initials: S
authors.lastname: Kulkarni
authors.forename: Shoeb Sheikh
authors.initials: SS
authors.lastname: Yakub
authors.forename: Sandeep
authors.initials: S
authors.lastname: Metgud
mesh_terms: D000293:Adolescent; D017607:Aluminum Compounds / Q000494:pharmacology*; D018786:Bone Substitutes; D017610:Calcium Compounds / Q000494:pharmacology*; D003809:Dentin, Secondary / Q000378:metabolism; D004338:Drug Combinations; D017886:Durapatite; D006171:Gutta-Percha; D006801:Humans; D007180:Incisor; D008297:Male; D008437:Maxilla; D010087:Oxides / Q000494:pharmacology*; D010485:Periapical Periodontitis / Q000601:surgery*; D053657:Platelet-Rich Plasma; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012389:Root Canal Obturation; D017640:Silicates / Q000494:pharmacology*; D019227:Tooth Apex / Q000187:drug effects / Q000254:growth & development*
chemical_list: D017607:Aluminum Compounds; D018786:Bone Substitutes; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D006171:Gutta-Percha; D017886:Durapatite