The potential relationship between QTc interval prolongation and ziprasidone treatment: three cases.
QTc interval prolongation may appear as a consequence of both typical and atypical antipsychotic treatments. Ziprasidone, which is effective in treating schizophrenia, is associated with QTc prolongation. Although the prolongation of QTc with ziprasidone treatment is often pronounced, there is a scarce number of cases reported about the relationship between ziprasidone and QTc prolongation. Of the three cases presented in this case series, two cases showed values exceeding 0.50 s with ziprasidone treatment.
Eker
S S
SS
Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey. saygineker@yahoo.com
Sarandol
A
A
Akkaya
C
C
Sivrioglu
E Y
EY
Kirli
S
S
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000009:adverse effects*; D013844:Thiazoles / Q000009:adverse effects*
D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone