title: Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.
abstract: OBJECTIVE
  During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce.
  
  
  METHODS
  From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression.
  
  
  RESULTS
  After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months.
  
  
  CONCLUSIONS
  Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern.
authors.affiliation: Scandanavian Quality Register for Thyroid and Parathyroid Surgery, Lund, Sweden. anders.bergenfelz@med.lu.se
authors.forename: A
authors.initials: A
authors.lastname: Bergenfelz
authors.forename: S
authors.initials: S
authors.lastname: Jansson
authors.forename: A
authors.initials: A
authors.lastname: Kristoffersson
authors.forename: H
authors.initials: H
authors.lastname: Mårtensson
authors.forename: E
authors.initials: E
authors.lastname: Reihnér
authors.forename: G
authors.initials: G
authors.lastname: Wallin
authors.forename: I
authors.initials: I
authors.lastname: Lausen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003625:Data Collection / Q000706:statistics & numerical data; D016208:Databases, Factual / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D019106:Postoperative Hemorrhage / Q000453:epidemiology / Q000209:etiology; D011446:Prospective Studies; D011785:Quality Assurance, Health Care / Q000706:statistics & numerical data; D012042:Registries / Q000706:statistics & numerical data*; D012086:Reoperation; D012307:Risk Factors; D013548:Sweden; D013959:Thyroid Diseases / Q000601:surgery*; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D055815:Young Adult