[Tartrate resistant acid phosphatase--TRACP-5b as a modern bone resorption marker].
The evaluation of bone metabolism in everyday practise is based on measurements of non-invasive bone markers. TRACP-5b has been considered as a potentially useful marker of bone resorption rate. It is an enzyme that is secreted by osteoclasts in the course of bone resorption. This review summarizes recent informations about TRACP 5b as a bone resorption marker in various clinical situations.
Nowak
Zbigniew
Z
Wojskowy Instytut Medyczny w Warszawie, CSK MON, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii, Poland. zbnowak@wp.pl
Konieczna
Maria
M
Saracyn
Marek
M
Wańkowicz
Zofia
Z
D000135:Acid Phosphatase / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001862:Bone Resorption / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D010010:Osteoclasts / Q000378:metabolism*; D000071681:Tartrate-Resistant Acid Phosphatase
D015415:Biomarkers; D007527:Isoenzymes; C000605510:ACP5 protein, human; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase