title: Diffusion-weighted imaging of primary brain lymphomas: effect of ADC value and signal intensity of T2-weighted imaging.
abstract: The purpose of this study was to determine whether apparent diffusion coefficient (ADC) value and T2 signal intensity (SI) in primary brain lymphomas affect their SI on diffusion-weighted images (DWI). On DWI of 16 brain lesions of 16 patients, 9 (56.2%) were hyperintense (grade-3), 4 (25%) partially hyperintense (grade-2) and 3 (18.8%) isointense (grade-1). The mean ADC value of grade-3 lesions was significantly lower than of grade-1 lesions (p=0.028). The grade-1 lesions had ADC values of more than 0.8 and contrast-to-noise ratios of less than 18 on T2-weighted images. Their ADC value and T2 signal intensity affect their SI on DWI.
authors.affiliation: Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, Japan.
authors.forename: Masuma
authors.initials: M
authors.lastname: Akter
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hirai
authors.forename: Keishi
authors.initials: K
authors.lastname: Makino
authors.forename: Mika
authors.initials: M
authors.lastname: Kitajima
authors.forename: Ryuji
authors.initials: R
authors.lastname: Murakami
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Fukuoka
authors.forename: Akira
authors.initials: A
authors.lastname: Sasao
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kuratsu
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity