[Dermatopathy associated with levamisole-induced reversible posterior leukoencephalopathy].
Levamisole is an antihelmintic drug that stimulates antibodies formation increasing both T response, and neutrophilic response, and quimiotaxis. It is used in dermatology for the treatment of plane warts, erythema multiforme, aphtous ulcers and, with prednisone, in lichen planus. With prolonged use this drug has been implicated in adverse dermatological reactions as lichenoid eruptions, ulcers and vasculitis. We present a 9-years old girl who developed a cutaneous eruption and a reverse leucoencephalopathy with a short treatment but high doses of the drug.
Boente
María Del C
Mdel C
Servicio de Dermatología, Hospital del Niño Jesús, Tucumán, Argentina. mboente@arnet.com.ar
Bibas Bonet
Hilda
H
Primc
Norma B
NB
D002648:Child; D003875:Drug Eruptions / Q000150:complications* / Q000209:etiology*; D005260:Female; D006801:Humans; D007978:Levamisole / Q000009:adverse effects*; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced* / Q000150:complications*; D012871:Skin Diseases / Q000188:drug therapy; D014860:Warts / Q000188:drug therapy
D007978:Levamisole