Novel multicomponent reactions involving isoquinoline or phenanthridine and activated acetylenic ester in the presence of heterocyclic NH or 1,3-dicarbonyl compounds.
Multicomponent reactions involving azines (phenanthridine or isoquinoline) and dimethyl acetylenedicarboxylate were undertaken in the presence of heterocyclic NH compounds (indole, 2-methyl indole, 3-methyl indole, carbazole and 3,6-dibromocarbazole) or 1,3-dicarbonyl compounds such as N,N'-dimethylbarbituric acid, 1,3-diethyl-2-thiobarbituric acid, acetylacetone, 1,3-diphenyl-1,3-propandione and cyclopentan-1,3-dione to generate enaminoesters in good yields.
Nassiri
Mahmoud
M
Department of Chemistry, The University of Sistan and Balouchestan, P.O. Box 98135-674, Zahedan, Iran.
Maghsoodlou
Malek Taher
MT
Heydari
Reza
R
Habibi Khorassani
Sayyed Mostafa
SM
D000114:Acetylene / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007546:Isoquinolines / Q000737:chemistry*; D010617:Phenanthridines / Q000737:chemistry*
D004952:Esters; D006571:Heterocyclic Compounds; D007546:Isoquinolines; D010617:Phenanthridines; C039109:isoquinoline; D000114:Acetylene