title: Actinomycetoma with negative culture: a therapeutic challenge.
abstract: Nocardia, Actinomyces, and Streptomyces species comprise the three broad classes of organisms that are causative for bacterial mycetoma. Although culture and molecular laboratory studies can usually identify the precise etiologic agent in bacterial mycetoma, occasionally these methods fail to clarify this situation. We report a classic clinical case of this infectious disease where usual diagnostic methods failed to identify the responsible organism, and discuss the empiric approach to such cases.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Austin
authors.initials: A
authors.lastname: Liu
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Maender
authors.forename: Neil
authors.initials: N
authors.lastname: Coleman
authors.forename: Sylvia
authors.initials: S
authors.lastname: Hsu
authors.forename: Ted
authors.initials: T
authors.lastname: Rosen
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D054242:Emigrants and Immigrants; D005188:False Negative Reactions; D005542:Forearm / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008828:Microbiological Techniques; D008875:Middle Aged; D008271:Mycetoma / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D009615:Nocardia / Q000302:isolation & purification*; D012867:Skin / Q000382:microbiology* / Q000473:pathology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination