title: Effect of fluconazole on the interactions between human neutrophils and Candida albicans.
abstract: The effects of fluconazole on the candidacidal activity of human neutrophils were investigated. Three clinical isolates of Candida albicans were studied in a colony count assay and the presence of fluconazole during incubation of yeasts with neutrophils had no effect on neutrophil candidacidal activity. These results, using a different assay and three additional isolates, confirm previous studies showing that fluconazole does not interfere with the ability of neutrophils to kill C. albicans.
authors.affiliation: Evans Memorial Department of Clinical Research and the Department of Medicine, Boston University Medical Center Hospital, Boston, MA 02118, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Sugar
authors.forename: J
authors.initials: J
authors.lastname: Tjia