title: Prospective comparative study on the acceptability of unsedated transnasal endoscopy in younger versus older patients.
abstract: OBJECTIVE
  The aim of this prospective study was to compare the acceptance and tolerance for unsedated transnasal esophagogastroduodenoscopy (EGD) between younger and older patients.
  
  
  BACKGROUND
  Little information is available on comparisons of younger and older patients with regard to acceptance and tolerance of transnasal EGD.
  
  
  METHODS
  A total of 260 patients were referred for unsedated transnasal EGD and divided into 2 groups according to their age: less than 60 years of age (group A, n=160) and 60 years of age and older (group B, n=100). A questionnaire for tolerance was completed by each patient (a validated 0 to 10 scale where "0" represents no discomfort/well tolerated and "10" represents severe discomfort/poorly tolerated).
  
  
  RESULTS
  In 94.4% of group A and 95.0% of group B, insertions were successfully completed (P>0.05). Between groups A and B, discomfort during nasal anesthesia (1.7+/-0.2 vs. 1.6+/-0.2) and overall tolerance during procedure (1.7+/-0.2 vs. 1.5+/-0.2) were similar (P>0.05). However, discomfort during insertion was significantly greater in group A than in group B (2.5+/-0.2 vs. 1.9+/-0.2, P=0.02). Of all, 97.4% of group A and 94.7% of group B were willing to undergo unsedated transnasal EGD in the future (P>0.05).
  
  
  CONCLUSIONS
  There was no significant difference in acceptability between younger and older patients for unsedated transnasal EGD. Otherwise, younger patients experienced significantly more discomfort during insertion than did older patients.
authors.affiliation: Department of Gastroenterology, Aso Iizuka Hospital, Iizuka, Japan.
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Murata
authors.forename: Kazuya
authors.initials: K
authors.lastname: Akahoshi
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Motomura
authors.forename: Noriaki
authors.initials: N
authors.lastname: Matsui
authors.forename: Masaru
authors.initials: M
authors.lastname: Kubokawa
authors.forename: Mitsuhide
authors.initials: M
authors.lastname: Kimura
authors.forename: Jiro
authors.initials: J
authors.lastname: Ouchi
authors.forename: Kuniomi
authors.initials: K
authors.lastname: Honda
authors.forename: Shingo
authors.initials: S
authors.lastname: Endo
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakamura
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Takayanagi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016145:Endoscopy, Digestive System / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose; D010342:Patient Acceptance of Health Care; D011446:Prospective Studies; D011795:Surveys and Questionnaires