Morphogenesis of the tumor patterns.
The mathematical modeling of tumor growth allows us to describe the most important regularities of these systems. A stochastic model, based on the most important processes that take place at the level of individual cells, is proposed to predict the dynamical behavior of the expected radius of the tumor and its fractal dimension. It was found that the tumor has a characteristic fractal dimension, which contains the necessary information to predict the tumor growth until it reaches a stationary state. This fractal dimension is distorted by the effects of external fluctuations. The model predicts a phenomenon which indicates stochastic resonance when the multiplicative and the additive noise are correlated.
Izquierdo-Kulich
Elena
E
Department of Physical-Chemistry, Faculty of Chemistry, University of Havana, Havana, Cuba. elenaik@fq.uh.cu
Nieto-Villar
Jos Manuel
JM
D003198:Computer Simulation; D017709:Fractals; D006801:Humans; D008954:Models, Biological; D008962:Models, Theoretical; D009024:Morphogenesis; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D013269:Stochastic Processes