Actinomycetoma with negative culture: a therapeutic challenge.
Nocardia, Actinomyces, and Streptomyces species comprise the three broad classes of organisms that are causative for bacterial mycetoma. Although culture and molecular laboratory studies can usually identify the precise etiologic agent in bacterial mycetoma, occasionally these methods fail to clarify this situation. We report a classic clinical case of this infectious disease where usual diagnostic methods failed to identify the responsible organism, and discuss the empiric approach to such cases.
Liu
Austin
A
Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
Maender
Jennifer L
JL
Coleman
Neil
N
Hsu
Sylvia
S
Rosen
Ted
T
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D054242:Emigrants and Immigrants; D005188:False Negative Reactions; D005542:Forearm / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008828:Microbiological Techniques; D008875:Middle Aged; D008271:Mycetoma / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D009615:Nocardia / Q000302:isolation & purification*; D012867:Skin / Q000382:microbiology* / Q000473:pathology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination