title: [Metabolic syndrome in young adults type 1 diabetic patients].
abstract: OBJECTIVE
  The aim of the study was to estimate the prevalence of metabolic syndrome (MS) in type 1 diabetic patients and to assess the relationship between the scores of MS components and body mass and metabolic control.
  
  
  METHODS
  165 patients aged 18-32 years with diabetes duration 8-26 years were included into the study. The height, weight, waist circumference and blood pressure were measured. HbA1c and plasma lipids concentrations were examined. Body mass index (BMI), waist/hip ratio (WHR) and daily dose of insulin were calculated. MS was diagnosed according to the definition of National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP) and International Diabetes Federation (IDF).
  
  
  RESULTS
  The prevalence of individual components of MS was 10.3% for high triglycerides, 7.3% for low HDL, 27.9% for high blood pressure, and 10.3% for abnormal waist circumference according to NGEP and 18.8% according to IDF definition. After assuming that all type 1 diabetic patients fulfilled criteria for hyperglycemia, the prevalence of MS diagnosed according to NCEP was 10.9% (95% CI 6.1-15.7) and according to IDF was the same 10.9% (95% CI 6.1-15.7). In 14 patients MS was diagnosed according to both definitions, whereas 4 met only the NCEP, and another 4 met only the IDF criteria. Rrelationships between the scores of MS components and BMI (p < 0.0001) and HbA1c (p = 0.002) were found. Patients with MS were older than the patients without MS (p = 0.003) and needed higher insulin doses (p = 0.028).
  
  
  CONCLUSIONS
  According to the NCEP and IDF criteria similar prevalence of MS is recognized in type 1 diabetic patients. Only in 2/3 of them MS is diagnosed according to both definitions. The most frequently occurring component of MS is elevated blood pressure. The scores of MS components are related to the presence of overweight and to poor metabolic control.
authors.affiliation: Klinika Chorób Dzieci I Katedry Pediatrii, Uniwersytetu Medycznego w Lodzi. agnieszka.szadkowska@wp.pl
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Szadkowska
authors.forename: Iwona
authors.initials: I
authors.lastname: Pietrzak
authors.forename: Joanna
authors.initials: J
authors.lastname: Bodalska-Lipińska
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Czerniawska
authors.forename: Marianna
authors.initials: M
authors.lastname: Wlodarczyk
authors.forename: Anna
authors.initials: A
authors.lastname: Swatko-Mikolajczyk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Bodalski
mesh_terms: D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D015897:Comorbidity; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000453:epidemiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence
chemical_list: D006442:Glycated Hemoglobin; D008055:Lipids