The genetics of vertebrate myogenesis.
The molecular, genetic and cellular bases for skeletal muscle growth and regeneration have been recently documented in a number of vertebrate species. These studies highlight the role of transient subcompartments of the early somite as a source of distinct waves of myogenic precursors. Individual myogenic progenitor populations undergo a complex series of cell rearrangements and specification events in different regions of the body, all of which are controlled by distinct gene regulatory networks. Collectively, these studies have opened a window into the morphogenetic and molecular bases of the different phases of vertebrate myogenesis, from embryo to adult.
Bryson-Richardson
Robert J
RJ
Victor Chang Cardiac Research Institute, 384 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia. r.bryson-richardson@victorchang.edu.au
Currie
Peter D
PD
D000818:Animals; D004622:Embryo, Mammalian; D004625:Embryo, Nonmammalian; D006257:Head / Q000196:embryology; D006321:Heart / Q000196:embryology / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D024510:Muscle Development / Q000235:genetics*; D009132:Muscles / Q000196:embryology*; D009928:Organ Specificity / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism / Q000502:physiology; D014714:Vertebrates / Q000235:genetics*
D012333:RNA, Messenger