title: [Treatment of intraventricular hemorrhage and hydrocephalus].
abstract: Most cases of intraventricular hemorrhage (IVH) occur secondary to spontaneous intracerebral or subarachnoid hemorrhage. The main concern is development of hydrocephalus, which is related to a poor prognosis. Over the last years, several treatment options for IVH have been introduced, but prospective data regarding the efficacy of those therapies (external ventricular drainage, intraventricular fibrinolysis, lumbar drainage, endoscopic hematoma evacuation) do not yet exist. This review focuses on combined therapy using an external ventricular drain and intraventricular fibrinolysis with r-TPA for IVH-associated initial occlusive hydrocephalus. Moreover, a continuing treatment strategy for persistent malresorptive communicating hydrocephalus using lumbar drainage is described.
authors.affiliation: Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054, Erlangen. hagen.huttner@uk-erlangen.de
authors.forename: H B
authors.initials: HB
authors.lastname: Huttner
authors.forename: D
authors.initials: D
authors.lastname: Staykov
authors.forename: J
authors.initials: J
authors.lastname: Bardutzky
authors.forename: C
authors.initials: C
authors.lastname: Nimsky
authors.forename: G
authors.initials: G
authors.lastname: Richter
authors.forename: A
authors.initials: A
authors.lastname: Doerfler
authors.forename: S
authors.initials: S
authors.lastname: Schwab
mesh_terms: D004322:Drainage; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D011379:Prognosis; D013129:Spinal Puncture; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed; D014696:Ventriculostomy