title: Clinical case report and literature review: metachronous colorectal splenic metastases.
abstract: A 52-year-old woman with a rising carcinoembryonic antigen CEA, no clinical or radiological findings, a negative colonoscopy, and a positron emission tomography (PET) scan that revealed an isolated hypermetabolic lesion in the spleen. The patient underwent splenectomy by laparoscopic surgery. The pathological study confirmed the presence of an isolated metastasis to the spleen. This case reveals the rare occurrence of isolated splenic metastases in the context of colorectal cancer and illustrates the role of PET when a patient shows a rising CEA with negative clinicoradiological studies.
authors.affiliation: Medical Oncology Department, Hospital Marina Alta, Dènia, Alacant, Spain. joanmagasent @telefonica.net
authors.forename: J M
authors.initials: JM
authors.lastname: Gasent Blesa
authors.forename: E
authors.initials: E
authors.lastname: de la Morena
authors.forename: J B
authors.initials: JB
authors.lastname: Laforga Canales
authors.forename: D
authors.initials: D
authors.lastname: Vilaseca Martínez
authors.forename: C
authors.initials: C
authors.lastname: Vázquez
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy; D000971:Antineoplastic Combined Chemotherapy Protocols; D002272:Carcinoembryonic Antigen / Q000097:blood; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008875:Middle Aged; D049268:Positron-Emission Tomography; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000556:secondary*
chemical_list: D002272:Carcinoembryonic Antigen; D019788:Fluorodeoxyglucose F18