title: [Hormone replacement therapy in peri- and postmenopausal women and breast cancer risk].
abstract: Hormone therapy (HT), in peri- and postmenopause has been associated with a modest increase in the risk of breast cancer. Hormones play a major role in tumorigenesis of breast cancer, and reproductive factors are known to influence breast cancer risk. Female sex steroids are used for contraception or menopause treatment by women of reproductive age and postmenopausal women respectively. This review reports recent published epidemiological evidence and randomised trials which examined the effect of HT on the risk of breast cancer.
authors.affiliation: Klinik für Frauenheilkunde und Geburtshilfe der Universität Regensburg, Caritaskrankenhaus St. Josef, Regensburg.
authors.forename: Stefan
authors.initials: S
authors.lastname: Buchholz
authors.forename: Felicitas
authors.initials: F
authors.lastname: Horn
authors.forename: Olaf
authors.initials: O
authors.lastname: Ortmann
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000139:chemically induced*; D002979:Climacteric / Q000187:drug effects*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
chemical_list: D003278:Contraceptives, Oral, Hormonal