Malignant prolactinoma with craniospinal metastasis in a 12-year-old boy.
The authors report the clinical features of and imaging studies on a rare case of pediatric malignant prolactinoma. A 12-year-old boy presented with ataxia, blurred vision, and consciousness disturbance. He had received transcranial surgery and adjuvant radiotherapy. However, the tumor regrew with craniospinal metastasis 16 months after the operation. The relevant literature was reviewed regarding the clinical presentation, pathogenesis, treatment approaches, and prognosis of malignant prolactinoma.
Huang
Abel Po-Hao
AP
Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7 Chung San South Road, Taipei, Taiwan, ROC.
Yang
Shih-Hung
SH
Yang
Chi-Cheng
CC
Kuo
Meng-Fai
MF
Wu
Mu Zon
MZ
Tu
Yong-Kwang
YK
D016543:Central Nervous System Neoplasms / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D019635:Neurosurgical Procedures; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D015175:Prolactinoma / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D011878:Radiotherapy