title: Physical health 25 years later: the predictive ability of neuroticism.
abstract: OBJECTIVE
  Neuroticism, a personality trait related to distress and emotional stability, is often correlated with physical symptoms and disease presence. Theorists have posited that chronic emotional instability creates physiological changes detrimental to health, yet most findings are based on cross-sectional analyses. The objective of the current study was to examine neuroticism assessed in 1973 and the likelihood of reporting physical conditions 25 years later.
  
  
  METHODS
  Participants included 21676 adult twins (n = 8143 intact twin pairs) ranging from 15 to 47 years old in 1973 who were assessed again between 1998 and 2002.
  
  
  METHODS
  Thirteen physical conditions, including chronic fatigue syndrome, ulcers, and coronary heart disease, were selected based on their prior theoretical and empirical links to personality traits.
  
  
  RESULTS
  Results indicate that the likelihood of having a physical condition is related to higher levels of prior neuroticism, with some associations attenuated when controlling for familial similarity.
  
  
  CONCLUSIONS
  Familial influences are most pronounced for conditions most related to systemic pain, suggesting genetic pathways between neuroticism and these pain experiences.
authors.affiliation: Department of Psychology, University of California, Irvine, CA 92697-7085, USA. scharles@uci.edu
authors.forename: Susan Turk
authors.initials: ST
authors.lastname: Charles
authors.forename: Margaret
authors.initials: M
authors.lastname: Gatz
authors.forename: Kenji
authors.initials: K
authors.lastname: Kato
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Pedersen
mesh_terms: D000293:Adolescent; D000328:Adult; D005544:Forecasting; D005824:Genetics, Behavioral; D006304:Health Status; D006801:Humans; D008875:Middle Aged; D009497:Neurotic Disorders / Q000235:genetics / Q000503:physiopathology*; D016017:Odds Ratio; D011795:Surveys and Questionnaires; D013548:Sweden