The oligoribonuclease gene in Streptomyces coelicolor is not transcriptionally or translationally coupled to adpA, a key bldA target.
Transcriptional analysis of the gene in Streptomyces coelicolor encoding oligoribonuclease indicates that it is not transcriptionally or translationally coupled to adpA, a key bldA target for morphological differentiation. Interestingly, construction and phenotypic analysis of an S. coelicolor oligoribonuclease null mutant revealed a conditional defect in morphological differentiation that is reminiscent of bldA and other known developmental mutants.
Sello
Jason K
JK
Department of Molecular Microbiology, John Innes Centre, Norwich, UK. jason_sello@brown.edu
Buttner
Mark J
MJ
D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D005095:Exoribonucleases / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D014176:Protein Biosynthesis; D012329:RNA, Bacterial / Q000235:genetics / Q000378:metabolism*; D012356:RNA, Transfer, Leu / Q000235:genetics / Q000378:metabolism*; D048372:Streptomyces coelicolor / Q000166:cytology / Q000201:enzymology* / Q000235:genetics; D014158:Transcription, Genetic
D001426:Bacterial Proteins; C107344:BldA tRNA, Streptomyces coelicolor; D012329:RNA, Bacterial; D012356:RNA, Transfer, Leu; D005095:Exoribonucleases; C094587:oligoribonuclease