title: Cell cycle stage specific application of cypermethrin and carbendazim to assess the genotoxicity in somatic cells of Hordeum vulgare L.
abstract: In this study, the genotoxicity of commonly used insecticide cypermethrin and fungicide carbendazim were examined on root meristem cells of Hordeum vulgare L. Cypermethrin and carbendazim were applied with concentrations of 0.05%, 0.1% and 0.5% at different presoaking durations of 7 h, 17 h and 27 h which falls into G(1), S and G(2) phases of cell cycle, respectively. The cytogenetic studies of the root meristem cells of Hordeum vulgare L. showed that S phase of the cell cycle was more sensitive in comparison to other phases of cell cycle.
authors.affiliation: Genotoxic Lab, Department of Botany, Faculty of Sciences, Udai Pratap Autonomous College, Varanasi 221002, India. genotoxicdob@yahoo.co.in
authors.forename: Parul
authors.initials: P
authors.lastname: Singh
authors.forename: Anjil Kumar
authors.initials: AK
authors.lastname: Srivastava
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Singh
mesh_terms: D001562:Benzimidazoles / Q000633:toxicity*; D002219:Carbamates / Q000633:toxicity*; D002453:Cell Cycle / Q000187:drug effects; D002869:Chromosome Aberrations / Q000139:chemically induced; D005659:Fungicides, Industrial / Q000633:toxicity*; D001467:Hordeum / Q000166:cytology / Q000187:drug effects* / Q000235:genetics; D007306:Insecticides / Q000633:toxicity*; D018519:Meristem / Q000166:cytology / Q000187:drug effects / Q000235:genetics; D009152:Mutagenicity Tests; D018517:Plant Roots / Q000166:cytology / Q000187:drug effects / Q000235:genetics; D011722:Pyrethrins / Q000633:toxicity*; D016196:S Phase / Q000187:drug effects
chemical_list: D001562:Benzimidazoles; D002219:Carbamates; D005659:Fungicides, Industrial; D007306:Insecticides; D011722:Pyrethrins; C017160:cypermethrin; C006698:carbendazim