[Review of effervescent technique in pharmaceutics research].
Effervescent technique, which can accelerate drug disintegration and dissolution, is usually applied in quick release preparations. Along with the development of pharmaceutical technique and theory, effervescent technique is used more and more extensively to adjust the behavior of drug release, such as in sustained and controlled release preparations, pulsatile drug delivery systems, and so on. This review demonstrated the new applying of effervescent technique in effervescent tablets, stomach floating forms, osmotic pump tablets and pulsatile drug delivery systems, adding to the critical common technique of effervescent forms in drug research. This will be benefit for the further research and development of effervescent technique.
Luo
Xiao-Jian
XJ
National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China. luoxj98@126.com
Xin
Hong-Liang
HL
Rao
Xiao-Yong
XY
Xiao
Zhi-Qiang
ZQ
Gao
Li-Li
LL
Sun
Ting-Ting
TT
Guo
Qi-Li
QL
D004304:Dosage Forms; D016503:Drug Delivery Systems; D006801:Humans; D009995:Osmosis; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D013607:Tablets
D004304:Dosage Forms; D004364:Pharmaceutical Preparations; D013607:Tablets