title: The role of prophylactic bilateral oophorectomy at the time of initial diagnosis of a unilateral ovarian metastasis in cases with colorectal adenocarcinoma.
abstract: OBJECTIVE
  In cases with a macroscopic unilateral ovarian metastasis of colorectal adenocarcinoma, a clear therapeutic policy regarding a prophylactic bilateral oophorectomy is lacking.
  
  
  METHODS
  Four cases of ovarian metastases of colorectal adenocarcinoma are presented.
  
  
  RESULTS
  Case 1 is a 63-year-old with ascending colon carcinoma, Dukes' C, and right oophorectomy due to metachronous ovarian metastasis. Case 2 is a 28-year-old with transverse colon carcinoma, Dukes' D, and right oophorectomy due to synchronous ovarian metastasis. Case 3 is a 40-year-old with rectal carcinoma, Dukes' B, and right oophorectomy due to metachronous ovarian metastasis. Case 4 is a 32-year-old with rectal carcinoma, Dukes' D, and bilateral oophorectomy due to synchronous and metachronous ovarian metastases. Later, in cases 1 and 3, in which a unilateral ovary was preserved, ovarian metastases to the preserved ovary were found and caused severe clinical symptoms. However, by that time their general condition did not permit any additional laparotomy.
  
  
  CONCLUSIONS
  Without other extensive metastases, if demonstrable diseases are found in a unilateral ovary, a prophylactic bilateral oophorectomy is recommended.
authors.affiliation: Department of Surgery, Rakuwakai-Otowa Hospital, Kyoto, Japan. rakuwadr011@rakuwadr.com
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takahashi
authors.forename: Ryuzaburo
authors.initials: R
authors.lastname: Kagawa
authors.forename: Ryoji
authors.initials: R
authors.lastname: Takeda
authors.forename: Shingo
authors.initials: S
authors.lastname: Sakata
authors.forename: Michihiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Nishizaki
authors.forename: Yoko
authors.initials: Y
authors.lastname: Iwasa
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery*; D000328:Adult; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods*