The BCG controversy.
The history of tuberculosis control by vaccination with Bacille Calmette-Guérin (BCG) is reviewed. Use of the vaccine is evaluated in light of conflicting results from trials of BCG efficacy. Explanatinations are suggested for the variations between trials, and the continued use of BCG as a vaccine against tuberculosis is discussed.
Verhoef
J
J
Eijkman-Winkler Institute for Medical and Clinical Microbiology, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.