An improved mechanism-based cross-linker for multiplexed kinase detection and inhibition in a complex proteome.
Liu
Kai
K
Deptartment of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117557, Singapore.
Kalesh
Karunakaran A
KA
Ong
Li Bing
LB
Yao
Shao Q
SQ
D000241:Adenosine / Q000737:chemistry / Q000494:pharmacology*; D000595:Amino Acid Sequence; D000818:Animals; D016466:CHO Cells; D002417:Cattle; D006224:Cricetinae; D003412:Cricetulus; D003432:Cross-Linking Reagents / Q000737:chemistry / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D009281:Naphthalenes / Q000737:chemistry / Q000494:pharmacology*; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D010766:Phosphorylation; D010770:Phosphotransferases / Q000032:analysis* / Q000037:antagonists & inhibitors* / Q000378:metabolism; D020543:Proteome / Q000378:metabolism*
D003432:Cross-Linking Reagents; D004791:Enzyme Inhibitors; D009281:Naphthalenes; D010455:Peptides; D020543:Proteome; C027717:2,3-naphthalenedicarboxaldehyde; D010770:Phosphotransferases; D000241:Adenosine