title: Synthesis of azoxabicyclo[3.3.1]nonanones based on diastereoselective reactions of 1,1-bis(trimethylsilyloxy)ketene acetals with isoquinolines and quinolines.
abstract: Densely functionalized azoxabicyclo[3.3.1]nonanones were prepared by regio- and diastereoselective condensation of 1,1-bis(silyloxy)ketene acetals with isoquinolinium and quinolinium salts and subsequent regioselective and stereospecific iodolactonization.
authors.affiliation: Institut für Chemie, Universität Rostock, Rostock, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Schmidt
authors.forename: Dirk
authors.initials: D
authors.lastname: Michalik
authors.forename: Sven
authors.initials: S
authors.lastname: Rotzoll
authors.forename: Ehsan
authors.initials: E
authors.lastname: Ullah
authors.forename: Christine
authors.initials: C
authors.lastname: Fischer
authors.forename: Helmut
authors.initials: H
authors.lastname: Reinke
authors.forename: Helmar
authors.initials: H
authors.lastname: Görls
authors.forename: Peter
authors.initials: P
authors.lastname: Langer
mesh_terms: D000080:Acetals / Q000737:chemistry*; D053961:Azabicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry; D005561:Formates / Q000737:chemistry; D007546:Isoquinolines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D011804:Quinolines / Q000737:chemistry*; D013237:Stereoisomerism; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: D000080:Acetals; D053961:Azabicyclo Compounds; D005030:Ethylenes; D005561:Formates; D007546:Isoquinolines; D007659:Ketones; D011804:Quinolines; D014297:Trimethylsilyl Compounds; C008223:ketene; C014667:methyl chloroformate