title: Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.
abstract: We report the preparation of organometallic Pd(allyl) dinuclear complexes in protein cages of apo-Fr by reactions with [Pd(allyl)Cl]2 (allyl = eta3-C3H5). One of the dinuclear complexes is converted to a trinuclear complex by replacing a Pd-coordinated His residue to an Ala residue. These results suggest that multinuclear metal complexes with various coordination structures could be prepared by the deletion or introduction of His, Cys, and Glu at appropriate positions on protein surface.
authors.affiliation: Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Abe
authors.forename: Jochen
authors.initials: J
authors.lastname: Niemeyer
authors.forename: Mizue
authors.initials: M
authors.lastname: Abe
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Takezawa
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ueno
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Hikage
authors.forename: Gerhard
authors.initials: G
authors.lastname: Erker
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Watanabe
mesh_terms: D001052:Apoferritins / Q000737:chemistry* / Q000235:genetics; D001665:Binding Sites; D018360:Crystallography, X-Ray; D003545:Cysteine / Q000737:chemistry / Q000235:genetics; D018698:Glutamic Acid / Q000737:chemistry / Q000235:genetics; D006639:Histidine / Q000737:chemistry / Q000235:genetics; D009154:Mutation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D018698:Glutamic Acid; D006639:Histidine; D010165:Palladium; D001052:Apoferritins; D003545:Cysteine