[Neutrophilic nitroblue tetrazolium reduction test in the diagnosis of neonatal bacterial infection].
The kinetics of a spontaneous peripheral blood neutrophilic nitroblue tetrazolium test (NBT-test) has been studied in neonatal infants. The reaction is shown to come to an end after 60-min reaction mixture thermostating, thereafter the proportion of activated neutrophils (PAN) does not change (PAN(infinity)). The reaction is described using the first-order kinetic equation that is similar to that having the rate constant k1. The calculations of PAN(infinity) and k1 allow a differential diagnosis of bacterial infections with and/or without pneumonia.
Tatarchenko
V V
VV
Linchevskiĭ
G L
GL
Vorob'eva
O V
OV
Gerasimov
I G
IG
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D018375:Neutrophil Activation / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D009580:Nitroblue Tetrazolium / Q000737:chemistry*; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000276:immunology
D009580:Nitroblue Tetrazolium