title: Nosocomial Streptococcus pneumoniae infection causing children's acute otitis media.
abstract: Streptococcus pneumoniae is the most frequent pathogen in young children's acute otitis media. It also plays a significant role in nosocomial ear infection in children, while it causes pneumonia with or without bacteremia in hospitalized elderly people. Multiple antibiotic resistant strains are prevalent among S. pneumoniae isolates from the respiratory tract of hospitalized patients in Hungary. This fact makes therapeutic reconsiderations concerning the use of oral beta-lactams mandatory. In this retrospective study two nosocomial outbreaks caused by multiresistant S. pneumoniae in two pediatric hospitals are described. The patients admitted with a chronic underlying disease (milk intolerance and gastro-oesophageal reflux were predominant) or respiratory tract infection acquired acute otitis media. Therapy with oral beta-lactams (first and second generation cephalosporins and amoxicillin), macrolides and co-trimoxazole was ineffective in most of the cases or resulted in transient improvement. In some cases acute otitis media resolved with the improvement of the underlying condition, in two cases administration of cefotaxime resulted in recovery and in one case mastoidectomy became necessary.
authors.affiliation: St. László Hospital, Gyàli ut 57, Budapest, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Marton
authors.forename: A
authors.initials: A
authors.lastname: Nagy
authors.forename: G
authors.initials: G
authors.lastname: Katona
authors.forename: F
authors.initials: F
authors.lastname: Fekete
authors.forename: P
authors.initials: P
authors.lastname: Votisky
authors.forename: Z
authors.initials: Z
authors.lastname: Lajos