title: High-resolution STM imaging of novel single G4-DNA molecules.
abstract: The molecular morphology of long G4-DNA wires made by a novel synthetic method was, for the first time, characterized by high-resolution scanning tunneling microscopy (STM). The STM images reveal a periodic structure seen as repeating "bulbs" along the molecules. These bulbs reflect the helix morphology of the wires. The STM measurements were supported by a statistical morphology analysis of the DNA pitch length and apparent height relative to the surface. In the absence of X-ray and NMR data for these wires, the STM measurements provide a unique alternative to characterize the helix morphology.
authors.forename: Errez
authors.initials: E
authors.lastname: Shapir
authors.forename: Lior
authors.initials: L
authors.lastname: Sagiv
authors.forename: Natalia
authors.initials: N
authors.lastname: Borovok
authors.forename: Tatiana
authors.initials: T
authors.lastname: Molotski
authors.forename: Alexander B
authors.initials: AB
authors.lastname: Kotlyar
authors.forename: Danny
authors.initials: D
authors.lastname: Porath
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure*; D054856:G-Quadruplexes; D016252:Microscopy, Scanning Tunneling
chemical_list: D004247:DNA