title: Understanding the concept of chemotherapy-related nausea: the patient experience.
abstract: The aim of this study was to explore the experience of chemotherapy-related nausea in patients with cancer. A qualitative study was carried out with 17 patients who had experienced nausea during their chemotherapy in the UK and USA. Nausea was described as distressing and complex symptom. Patients attempted to construct an understanding of nausea using cognitive processes such as analysing their experience of nausea and related symptoms, attributing causation to nausea and comparing their experiences not only to their own expectations, but also to others' symptom experiences. A number of concurrent and associated symptoms linked with nausea were identified. Preliminary evidence emerged for nausea as part of a cluster of symptoms. Anti-emetic medication, provider-directed management strategies and self-management strategies were used by patients to minimize the effects of nausea. Self-management techniques, such as dietary strategies, were rooted in participants' understanding of nausea and their beliefs about what caused nausea, and there was little evidence of guidance from professionals beyond advice about medication management. This study reveals some of the complexities behind chemotherapy-induced nausea, including a potential symptom cluster, and contributes towards a clearer understanding of this symptom and its effects on patients' lives.
authors.affiliation: University of Manchester, School of Nursing, Midwifery & Social Work, Manchester, UK. alex.molassiotis@manchester.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Molassiotis
authors.forename: C T
authors.initials: CT
authors.lastname: Stricker
authors.forename: B
authors.initials: B
authors.lastname: Eaby
authors.forename: L
authors.initials: L
authors.lastname: Velders
authors.forename: P A
authors.initials: PA
authors.lastname: Coventry
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000932:Antiemetics / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced* / Q000517:prevention & control / Q000523:psychology; D009369:Neoplasms / Q000188:drug therapy* / Q000523:psychology; D011788:Quality of Life
chemical_list: D000932:Antiemetics