title: Combined treatment with oral kanamycin and parenteral antibiotics for a case of persistent bacteremia and intestinal carriage with Campylobacter coli.
abstract: Campylobacter coli (C. coli) is a rare pathogen of bacteremia, but in immunocompromised hosts, C. coli occasionally causes bacteremia which can be refractory to antibiotic treatment. We report a case of C. coli bacteremia in a patient with X-linked agammaglobulinemia. Bacteremia relapsed repeatedly in spite of treatment with combined intravenous antibiotics. C. coli was observed in the biopsy specimens from the intestinal mucosa, suggesting intestinal carriage and reservoir of recurring infection. The addition of oral kamamycin with intravenous antibiotics was successful in eradicating C. coli from the blood and intestine.
authors.affiliation: Department of Infectious Diseases, Graduate School of Medicine, The University of Tokyo.
authors.forename: Haruka
authors.initials: H
authors.lastname: Okada
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Kitazawa
authors.forename: Sohei
authors.initials: S
authors.lastname: Harada
authors.forename: Satoru
authors.initials: S
authors.lastname: Itoyama
authors.forename: Shuji
authors.initials: S
authors.lastname: Hatakeyama
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ota
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Koike
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002169:Campylobacter Infections / Q000175:diagnosis / Q000188:drug therapy*; D017000:Campylobacter coli; D004359:Drug Therapy, Combination; D004403:Dysentery / Q000188:drug therapy; D004696:Endocarditis / Q000188:drug therapy; D006801:Humans; D007262:Infusions, Intravenous; D007612:Kanamycin / Q000008:administration & dosage*; D008297:Male; D008826:Microbial Sensitivity Tests; D010019:Osteomyelitis / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D007612:Kanamycin