Antifungal stilbenoids from Stemona japonica.
Three new dihydrostilbenes, stilbostemins P-R (1-3), and a new dihydrophenanthrene, stemanthrene G (4), were isolated from the roots of Stemona japonica together with three known bibenzyls, 3,5-dihydroxy-2'-methoxy bibenzyl (5), 3,3'-dihydroxy-2,5'-dimethoxy bibenzyl (6), and 3,5,2'-trihydroxy-4-methyl bibenzyl (7). Their structures were elucidated by spectroscopic analyses. Compounds 5 and 6 exhibited strong antifungal activities against Candida albicans.
Zhang
Ya-Zhong
YZ
Anhui Institute for Drug Control, Hefei, China.
Xu
Guo-Bing
GB
Zhang
Tong
T
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D018517:Plant Roots / Q000737:chemistry; D041901:Stemonaceae / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry* / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D013267:Stilbenes