Diffusion-weighted imaging of primary brain lymphomas: effect of ADC value and signal intensity of T2-weighted imaging.
The purpose of this study was to determine whether apparent diffusion coefficient (ADC) value and T2 signal intensity (SI) in primary brain lymphomas affect their SI on diffusion-weighted images (DWI). On DWI of 16 brain lesions of 16 patients, 9 (56.2%) were hyperintense (grade-3), 4 (25%) partially hyperintense (grade-2) and 3 (18.8%) isointense (grade-1). The mean ADC value of grade-3 lesions was significantly lower than of grade-1 lesions (p=0.028). The grade-1 lesions had ADC values of more than 0.8 and contrast-to-noise ratios of less than 18 on T2-weighted images. Their ADC value and T2 signal intensity affect their SI on DWI.
Akter
Masuma
M
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, Japan.
Hirai
Toshinori
T
Makino
Keishi
K
Kitajima
Mika
M
Murakami
Ryuji
R
Fukuoka
Hirofumi
H
Sasao
Akira
A
Kuratsu
Jun-ichi
J
Yamashita
Yasuyuki
Y
D000328:Adult; D000368:Aged; D000465:Algorithms; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity