title: The 126,000 molecular weight protein of tobacco mosaic virus is associated with host chromatin in mosaic-diseased tobacco plants.
abstract: The infection-related polypeptide of apparent molecular weight (MW) 116,000, which previously was shown to be associated with host chromatin from mosaic-diseased leaves of tobacco mosaic virus (TMV)-infected tobacco, comigrated during electrophoresis in polyacrylamide gels with the 126,000 molecular weight protein translated from TMV RNA in vitro. Limited proteolysis of the 116,000 MW polypeptide and of the 126,000 MW translational product with protease V8 generated the same peptides, indicating that the proteins were very similar or identical. Thus, the virally coded 126,000 MW protein is associated with host chromatin. The possibility that viruses may perturb host metabolism at the genome level is discussed.
authors.affiliation: Department of Plant Physiology, Agricultural University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands.
authors.forename: H J
authors.initials: HJ
authors.lastname: van Telgen
authors.forename: R W
authors.initials: RW
authors.lastname: Goldbach
authors.forename: L C
authors.initials: LC
authors.lastname: van Loon