title: Status epilepticus and intrathecal fluorescein: anesthesia providers beware.
abstract: Fluorescein is a fluorochrome dye occasionally administered by intrathecal injection to identify and localize cerebrospinal fluid leaks. Although generally considered to be a benign intervention, intrathecal administration of fluorescein has resulted in adverse events. We report a case of status epilepticus after intrathecal administration of fluorescein. Anesthesia providers should be aware of complications associated with intrathecal fluorescein use and be prepared to manage neurologic complications during the perioperative period.
authors.affiliation: Department of Anesthesiology, Mayo Clinic, 200 First Street, S.W., Rochester, MN 55905, USA.
authors.forename: Adam K
authors.initials: AK
authors.lastname: Jacob
authors.forename: John A
authors.initials: JA
authors.lastname: Dilger
authors.forename: James R
authors.initials: JR
authors.lastname: Hebl
mesh_terms: D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis*; D005260:Female; D019793:Fluorescein / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007278:Injections, Spinal; D008875:Middle Aged; D013226:Status Epilepticus / Q000139:chemically induced*
chemical_list: D019793:Fluorescein