Corticosteroid treatment of behaviour, language and motor regression in childhood disintegrative disorder.
Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two children with apparent CDD, who showed amelioration of behaviour, language and motor regression after corticosteroid treatment.
Mordekar
Santosh R
SR
Ryegate Children's Centre, Tapton Crescent Road, Sheffield, UK. santosh.mordekar@sch.nhs.uk
Prendergast
Michael
M
Chattopadhyay
Arup K
AK
Baxter
Peter S
PS
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D002659:Child Development Disorders, Pervasive / Q000150:complications / Q000188:drug therapy* / Q000523:psychology*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007802:Language; D007805:Language Development Disorders / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy* / Q000209:etiology; D012720:Severity of Illness Index
D000305:Adrenal Cortex Hormones