Stabbing in the BAK--an original target for avirulence genes of plant pathogens.
Paradoxically, plant pathogens possess avirulence genes that render them avirulent in resistant hosts. In Cell Host & Microbe, Shan et al. (2008) show that the original role of the Pseudomonas syringae avirulence genes AvrPto and AvrPtoB is to target BAK1, a protein kinase important in hormone and innate immunity signaling.
Boller
Thomas
T
Zurich-Basel Plant Science Center, Botanisches Institut der Universität Basel, Hebelstrasse 1, CH-4056 Basel, Switzerland. thomas.boller@unibas.ch
D029681:Arabidopsis Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D010935:Plant Diseases / Q000276:immunology* / Q000382:microbiology; D010944:Plants / Q000276:immunology* / Q000382:microbiology; D011485:Protein Binding; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D044224:Pseudomonas syringae / Q000472:pathogenicity*; D037521:Virulence Factors / Q000235:genetics / Q000378:metabolism*
D029681:Arabidopsis Proteins; D001426:Bacterial Proteins; D037521:Virulence Factors; C081695:avrPto protein, Pseudomonas syringae; C463660:BAK1 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases