title: The centrosome is a polyfunctional multiprotein cell complex.
abstract: Contemporary knowledge about centrosome proteins and their ensembles, which can be divided into several functional groups--microtubule-nucleating proteins, microtubule-anchoring proteins, centriole-duplication proteins, cell cycle control proteins, primary cilia growth regulation proteins, and proteins of regulation of cytokinesis--is reviewed. Structural-temporal classification of centrosomal proteins and the scheme of interconnection between the different centrosomal protein complexes are presented.
authors.affiliation: Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia. irina_alieva@belozersky.msu.ru
authors.forename: I B
authors.initials: IB
authors.lastname: Alieva
authors.forename: R E
authors.initials: RE
authors.lastname: Uzbekov
mesh_terms: D000818:Animals; D002502:Centrioles / Q000737:chemistry / Q000378:metabolism; D018385:Centrosome / Q000145:classification / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D046912:Multiprotein Complexes / Q000145:classification / Q000378:metabolism / Q000502:physiology*; D011485:Protein Binding
chemical_list: D046912:Multiprotein Complexes