Synthesis of 4a-carba-alpha-D-lyxofuranose from 2,3-O-isopropylidene-L-erythruronolactone via Tebbe-mediated cascade reaction.
A new, efficient and highly diastereoselective approach for the synthesis of 1,2,3,5-tetraacetylcarba-alpha-D-lyxofuranose from D-ribose is reported via one-pot conversion of to using Tebbe reagent which involves a cascade reaction sequence of methylenation, cleavage of isopropyl group, carbocyclization and again methylenation.
Prasad Mishra
Girija
G
Organic Division III, Indian Institute of Chemical Technology, Hyderabad, India.
Venkata Ramana
G
G
Venkateswara Rao
B
B
D054329:Carbasugars / Q000138:chemical synthesis*; D007783:Lactones / Q000737:chemistry*; D009005:Monosaccharides / Q000737:chemistry*
C531504:2,3-O-isopropylidene-L-erythruronolactone; C531503:4a-carba-alpha-D-lyxofuranose; D054329:Carbasugars; D007783:Lactones; D009005:Monosaccharides