title: [Long-acting medications for the treatment of hyperkinetic disorders - a systematic review and European treatment guideline. Part 1: overview and recommendations].
abstract: A panel of experts from several European countries has accomplished a systematic review of published and unpublished data on the use of long-acting medications in ADHD and hyperkinetic disorder. Based on this analysis detailed recommendations about the use of these drugs in practice have been developed: (1) Long-acting preparations should be licensed and used; (2) They should not completely replace short-acting drugs (which will be the initial treatment for many children in view of cost and the greater flexibility of dosing). Individual clinical choices are necessary. (3) Both ATX and extended-release stimulants should be available. In addition, detailed recommendations will be made with regard to the criteria to be applied in choosing a preparation for the individual patient.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut für Seelische Gesundheit, Mannheim.
authors.forename: Tobias
authors.initials: T
authors.lastname: Banaschewski
authors.forename: David
authors.initials: D
authors.lastname: Coghill
authors.forename: Paramala
authors.initials: P
authors.lastname: Santosh
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zuddas
authors.forename: Philip
authors.initials: P
authors.lastname: Asherson
authors.forename: Jan
authors.initials: J
authors.lastname: Buitelaar
authors.forename: Marina
authors.initials: M
authors.lastname: Danckaerts
authors.forename: Manfred
authors.initials: M
authors.lastname: Döpfner
authors.forename: Stephen V
authors.initials: SV
authors.lastname: Faraone
authors.forename: Aribert
authors.initials: A
authors.lastname: Rothenberger
authors.forename: Joseph
authors.initials: J
authors.lastname: Sergeant
authors.forename: Hans-Christoph
authors.initials: HC
authors.lastname: Steinhausen
authors.forename: Edmund J S
authors.initials: EJ
authors.lastname: Sonuga-Barke
authors.forename: Eric
authors.initials: E
authors.lastname: Taylor
mesh_terms: D000662:Amphetamines / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D001289:Attention Deficit Disorder with Hyperactivity / Q000097:blood / Q000188:drug therapy*; D001682:Biological Availability; D000697:Central Nervous System Stimulants / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D002648:Child; D003692:Delayed-Action Preparations; D019317:Evidence-Based Medicine; D006801:Humans; D008657:Metabolic Clearance Rate / Q000502:physiology; D008774:Methylphenidate / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D017410:Practice Guidelines as Topic
chemical_list: D000662:Amphetamines; D000697:Central Nervous System Stimulants; D003692:Delayed-Action Preparations; D008774:Methylphenidate