title: Highly Direct alpha-Selective Glycosylations of 3,4-O-Carbonate-Protected 2-Deoxy- and 2,6-Dideoxythioglycosides by Preactivation Protocol.
abstract: A new efficient pre-activation method for the highly alpha-stereoselective glycosylation of 2-deoxysugars and 2,6-dideoxysugars has been developed using 2-deoxy- and 2,6-dideoxythioglycosides as glycosyl donors. The approach allows a wide range of glycosyl acceptors and donors to be used; the alpha-selectivity is very good to excellent.
authors.affiliation: The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd #38, Beijing 100083, China.
authors.forename: Yin-Suo
authors.initials: YS
authors.lastname: Lu
authors.forename: Qin
authors.initials: Q
authors.lastname: Li
authors.forename: Li-He
authors.initials: LH
authors.lastname: Zhang
authors.forename: Xin-Shan
authors.initials: XS
authors.lastname: Ye
mesh_terms: D002236:Carbohydrate Conformation; D002254:Carbonates / Q000737:chemistry*; D006031:Glycosylation; D013237:Stereoisomerism; D013865:Thioglycosides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002254:Carbonates; D013865:Thioglycosides