AA amyloidosis due to chronic oxalate arthritis and vasculitis in a patient with secondary oxalosis after jejunoileal bypass surgery.
We report a case of a woman with secondary oxalosis after jejunoileal bypass surgery for obesity, who presented with oxalate stone disease and renal insufficiency requiring dialysis. Thirty years after surgery, longstanding osteoarticular symptoms were recognized as oxalate arthritis. Eventually, she also developed oxalate vasculitis, which improved with corticoid treatment and intensification of dialysis. Work-up for kidney transplantation revealed AA amyloidosis on gastric and colonic biopsies. Since no other cause of chronic inflammation could be identified, it was concluded that the amyloidosis was secondary to oxalate arthritis and vasculitis. To our knowledge, this is the first report on this association.
Cornelis
Tom
T
Department of Nephrology and Renal Transplantation, University Hospitals Leuven, B-3000 Leuven, Belgium.
Bammens
Bert
B
Lerut
Evelyne
E
Cosyn
Luc
L
Goovaerts
Gerda
G
Westhovens
René
R
Vanrenterghem
Yves
Y
D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D001168:Arthritis / Q000150:complications* / Q000378:metabolism*; D005260:Female; D006801:Humans; D006959:Hyperoxaluria / Q000209:etiology / Q000378:metabolism; D007581:Jejunoileal Bypass / Q000009:adverse effects*; D008286:Malabsorption Syndromes / Q000209:etiology / Q000378:metabolism; D008875:Middle Aged; D009397:Nephrocalcinosis / Q000209:etiology / Q000473:pathology; D009767:Obesity, Morbid / Q000601:surgery; D010070:Oxalates / Q000378:metabolism*; D013997:Time Factors; D014657:Vasculitis / Q000150:complications*
D010070:Oxalates