title: Corticosteroid treatment of behaviour, language and motor regression in childhood disintegrative disorder.
abstract: Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two children with apparent CDD, who showed amelioration of behaviour, language and motor regression after corticosteroid treatment.
authors.affiliation: Ryegate Children's Centre, Tapton Crescent Road, Sheffield, UK. santosh.mordekar@sch.nhs.uk
authors.forename: Santosh R
authors.initials: SR
authors.lastname: Mordekar
authors.forename: Michael
authors.initials: M
authors.lastname: Prendergast
authors.forename: Arup K
authors.initials: AK
authors.lastname: Chattopadhyay
authors.forename: Peter S
authors.initials: PS
authors.lastname: Baxter
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D002659:Child Development Disorders, Pervasive / Q000150:complications / Q000188:drug therapy* / Q000523:psychology*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007802:Language; D007805:Language Development Disorders / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy* / Q000209:etiology; D012720:Severity of Illness Index
chemical_list: D000305:Adrenal Cortex Hormones