title: Catalytic durability of magnetoproteoliposomes captured by high-gradient magnetic forces in a miniature fixed-bed reactor.
abstract: Cytochrome c-oxidase, used as a model membrane-bound enzyme, was embedded in phospholipid bilayer membranes, attached to nanometer-sized Fe(3)O(4) colloids (so-called magnetoliposomes). In comparison with the lipid-depleted free enzyme, both the activity and the enzymatic stability of the complexes, stored at 4 degrees C, were considerably enhanced. These beneficial properties of magnetoproteoliposomes have been successfully exploited in a magnetically controlled fixed-bed bioreactor, operating in a continuous flow regime. (c) 1996 John Wiley & Sons, Inc.
authors.affiliation: Interdisciplinary Research Centre, Katholieke Universiteit Leuven, Campus Kortrijk, B-8500 Kortrijk, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: De Cuyper
authors.forename: B
authors.initials: B
authors.lastname: De Meulenaer
authors.forename: P
authors.initials: P
authors.lastname: Van der Meeren
authors.forename: J
authors.initials: J
authors.lastname: Vanderdeelen