The Biomaterialbank of the German Competence Network of Heart Failure (CNHF) is a valuable resource for biomedical and genetic research.
Genetic research on heart failure (HF) requires large cohorts of well-phenotyped patients. The German Competence Network of Heart Failure (CNHF) organized a biobank in 2004 to supply the necessary infrastructure and standard operating procedures (SOPs) for a centralized collection of blood specimen. We centralized data and collected serum, plasma and DNA of well characterized HF subjects all over Germany. Different pseudonyms were created automatically to address data safety and other concerns about privacy. Thus far, we have collected 85,000 sample specimen from 9,500 prospectively evaluated patients with HF. Detailed medical data were prospectively acquired together with corresponding blood samples. In 2008 clinician-scientists can apply for access to the material. Our biobank represents a major facet of the CNHF and has already documented research and clinical utility.
Posch
Maximilian G
MG
Gelbrich
Götz
G
Pieske
Burkert
B
Lehmkuhl
Elke
E
Angermann
Christiane E
CE
Störk
Stefan
S
Neumann
Till
T
Düngen
Hans-Dirk
HD
Scheffold
Thomas
T
Müller-Tasch
Thomas
T
Maisch
Bernhard
B
Rauchhaus
Mathias
M
Dietz
Rainer
R
Ozcelik
Cemil
C
D001771:Blood Banks / Q000592:standards*; D030541:Databases, Genetic / Q000592:standards*; D005858:Germany; D006333:Heart Failure / Q000145:classification / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D011446:Prospective Studies; D013048:Specimen Handling / Q000379:methods / Q000592:standards; D014015:Tissue Banks / Q000592:standards*