Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.
Phytochemical investigation of the fruits of Momordica charantia resulted in the isolation and characterization of two new (1 and 2) and eight known cucurbitane-type triterpene glycosides and one cucurbitane-type triterpene. The glycosides (7beta,25-dimethoxycucurbita-5(6),23( E)-dien-19-al 3- O-beta-D-allopyranoside (1); 25-methoxycucurbita-5(6),23(E)-dien-19-ol 3-O-beta-D-allopyranoside (2); momordicosides A, F (1), F (2), G, K, and L; and goyaglycoside-c and goyaglycoside-d) and the triterpene [3 beta,7 beta,25-trihydroxycucurbita-5,23(E)-dien-19-al] were characterized by physical, chemical, and spectroscopic techniques, including 1D- and 2D-NMR as well as by comparison with the reported data.
Liu
Yi
Y
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, Mississippi, USA.
Ali
Zulfiqar
Z
Khan
Ikhlas A
IA
D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D029777:Momordica charantia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes