Streptomycin suppression of ambivalent phage mutations.
Phenotypic repair by streptomycin has been studied in amber mutants of phage T4 on su- strains, as has the interference of SmR mutations with amber suppressors. The repair seems not to be specific; however a temporal specificity of streptomycin action has been demonstrated by means of pulse experiments. The dependence of the efficiency of suppression upon experimental condition is also reported.
Reale Scafati
A
A
Physics Laboratory, Istituto Superiore di Sanità, Rome, Italy.