title: Biomaterials and biofunctionality in layered macromolecular assemblies.
abstract: Recent research in the field of LbL assembly is summarized and categorized as fabrication, sensing, drug release/delivery, and cell technology. Special emphasis is given to topics such as cell-membrane-mimic assembly, fabrication of free-standing biomolecular structures including protein microtubes, detection of DNA adducts and reactive metabolites, DNA hybridization analysis, sensing of toxic and bio-active chemicals, entrapment of proteins and DNA, biocomponent carriers with barcode encoding, release and delivery of DNA plasmids, multiagent delivery, smart defense capsules and oxidation-resistant films, vector introduction to cells, patterned cell culturing and microfluidic microreactors, stem cell differentiation, cellular uptake and degradation, and control of cellular apoptosis.
authors.affiliation: World Premier International (WPI) Research Center for Materials, Nanoarchitectonics (MANA) and Supermolecules Group, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan. ariga.katsuhiko@nims.go.jp
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Ariga
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Hill
authors.forename: Qingmin
authors.initials: Q
authors.lastname: Ji
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000737:chemistry; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D036103:Nanotechnology
chemical_list: D001672:Biocompatible Materials; D046911:Macromolecular Substances