Conjugation of spermine facilitates cellular uptake and enhances antitumor and antibiotic properties of highly lipophilic porphyrins.
Hahn
Frank
F
Kekulé-Insitut für Organische Chemie und Biochemie, LIMES Institute, Program Unit Membrane Biology and Lipid Biochemistry, Rheinische Friedrich Wilhelms Universität Bonn, Gerhard Domagk Str. 1, 53121 Bonn, Germany.
Schmitz
Katja
K
Balaban
Teodor S
TS
Bräse
Stefan
S
Schepers
Ute
U
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008055:Lipids / Q000737:chemistry*; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D013096:Spermine / Q000737:chemistry* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D008055:Lipids; D011166:Porphyrins; D013096:Spermine