title: Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions.
authors.affiliation: Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
authors.forename: Sam
authors.initials: S
authors.lastname: Hay
authors.forename: Jiayun
authors.initials: J
authors.lastname: Pang
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Monaghan
authors.forename: Xi
authors.initials: X
authors.lastname: Wang
authors.forename: Rhiannon M
authors.initials: RM
authors.lastname: Evans
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Sutcliffe
authors.forename: Rudolf K
authors.initials: RK
authors.lastname: Allemann
authors.forename: Nigel S
authors.initials: NS
authors.lastname: Scrutton
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry*; D002384:Catalysis; D001411:Geobacillus stearothermophilus / Q000201:enzymology; D006859:Hydrogen / Q000737:chemistry*; D007554:Isotopes; D007700:Kinetics; D008956:Models, Chemical; D015335:Molecular Probes / Q000737:chemistry; D009243:NAD / Q000737:chemistry; D009249:NADP / Q000737:chemistry; D010084:Oxidation-Reduction; D010453:Peptide Synthases / Q000737:chemistry*; D011789:Quantum Theory; D020124:Thermotoga maritima / Q000201:enzymology
chemical_list: D007554:Isotopes; D015335:Molecular Probes; D009243:NAD; D009249:NADP; D006859:Hydrogen; D000426:Alcohol Dehydrogenase; D010453:Peptide Synthases; C020041:dihydrofolate synthetase