title: Terminal aziridines by alpha-deprotonation/electrophile trapping of N-protected aziridine.
abstract: N-tert-Butylsulfonyl and N-tert-butylsulfinyl aziridine undergo alpha-lithiation/electrophile trapping providing a new entry to terminal aziridines. With N-tert-butylsulfinyl aziridine complete asymmetric induction is observed alpha to nitrogen.
authors.affiliation: Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK. david.hodgson@chem.ox.ac.uk
authors.forename: David M
authors.initials: DM
authors.lastname: Hodgson
authors.forename: Steven P
authors.initials: SP
authors.lastname: Hughes
authors.forename: Amber L
authors.initials: AL
authors.lastname: Thompson
authors.forename: Tom D
authors.initials: TD
authors.lastname: Heightman
mesh_terms: D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry; D015394:Molecular Structure; D011522:Protons; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D011522:Protons; D008094:Lithium