title: Treatment of idiopathic sclerosing inflammation of the orbit (myositis) with infliximab.
abstract: OBJECTIVE
  We report the successful use of infliximab in a young patient with idiopathic sclerosing orbital inflammation (myositis).
  
  
  METHODS
  We describe the patient's medical records and review the literature.
  
  
  RESULTS
  Idiopathic myositis in this patient could not be satisfactorily treated with corticosteroids or chemotherapy. Biopsy showed sclerosing orbital inflammation. The patient had a prompt and sustained response with infliximab and methotrexate treatment.
  
  
  CONCLUSIONS
  Infliximab and methotrexate might be considered in patients with idiopathic sclerosing orbital inflammation (myositis).
authors.affiliation: St Erik's Eye Hospital, Karolinska Institute, Stockholm, Sweden. sven.sahlin@sankterik.se
authors.forename: Sven
authors.initials: S
authors.lastname: Sahlin
authors.forename: Börje
authors.initials: B
authors.lastname: Lignell
authors.forename: Maria
authors.initials: M
authors.lastname: Williams
authors.forename: Maryam
authors.initials: M
authors.lastname: Dastmalchi
authors.forename: Abiel
authors.initials: A
authors.lastname: Orrego
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D000069285:Infliximab; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000627:therapeutic use*; D055622:Orbital Myositis / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D019233:Retreatment; D012598:Sclerosis; D017211:Treatment Failure
chemical_list: D000305:Adrenal Cortex Hormones; D000911:Antibodies, Monoclonal; D000069285:Infliximab; D008727:Methotrexate