Implications of blood-brain barrier disruption in ALS.
Our letter to the editor addresses important questions regarding the role of the blood-spinal cord barrier in amyotrophic lateral sclerosis. The novel finding of barrier dysfunction in ALS has implications for disease pathogenesis. This discussion should prove of widespread interest to researchers and may help in formulating various new therapeutic strategies to protect barrier function and thus extend functionality and lifespan in ALS patients.
Garbuzova-Davis
Svitlana
S
Saporta
Samuel
S
Sanberg
Paul R
PR
D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000503:physiopathology*; D001812:Blood-Brain Barrier / Q000503:physiopathology*; D006801:Humans