Disturbances of self-other distinction after stimulation of the extrastriate body area in the human brain.
In a recent experiment with functional magnetic-resonance imaging, we found that brain activity in the extrastriate body area (EBA) distinguished between observed self- and other-generated movements, being significantly higher during observation of someone else's movement. Here, we investigated further the role of EBA in self-other distinctions using low-frequency repetitive transcranial magnetic stimulation (rTMS). As compared with rTMS applied over a control site, rTMS applied over the EBA increased reaction times, without affecting accuracy, for the detection of other-generated movements. Performance on a control motion-direction detection task was unaffected. These findings provide additional evidence for the role of the EBA in processing information necessary for identifying ourselves as agents of self-generated movements.
David
Nicole
N
University of Cologne, Cologne, Germany. ndavid@uke.de
Jansen
Marije
M
Cohen
Michael X
MX
Osswald
Katja
K
Molnar-Szakacs
Istvan
I
Newen
Albert
A
Vogeley
Kai
K
Paus
Tomás
T
D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D004532:Ego; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009068:Movement / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D050781:Transcranial Magnetic Stimulation; D055815:Young Adult