Systemic fluoride poisoning and death from inhalational exposure to sulfuryl fluoride.
We report a poisoning death from inhalational exposure to the gas fumigants chloropicrin and sulfuryl fluoride. The patient displayed both local irritant effects of chloropicrin and systemic effects of sulfuryl fluoride. The clinical course, marked by initial hypocalcemia, delayed onset of ventricular dysrhythmias, and death, is consistent with fluoride being the predominant mechanism of toxicity with sulfuryl fluoride.
Schneir
Aaron
A
University of San Diego Medical Center, San Diego, California 92103-8676, USA. aschneir@ ucsd.edu
Clark
Richard F
RF
Kene
Mamta
M
Betten
David
D
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D004781:Environmental Exposure / Q000009:adverse effects; D017809:Fatal Outcome; D005260:Female; D005458:Fluoride Poisoning / Q000209:etiology; D005651:Fumigation; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000506:poisoning*; D006996:Hypocalcemia / Q000139:chemically induced; D019570:Inhalation Exposure; D007306:Insecticides / Q000506:poisoning*; D013441:Sulfinic Acids / Q000506:poisoning*
D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D013441:Sulfinic Acids; C048899:sulfuryl fluoride; C100187:chloropicrin