title: Reagent switchable stereoselective beta(1,2) mannoside mannosylation: OH-2 of mannose is a privileged acceptor.
abstract: The discovery of novel conditions for highly beta-stereoselective (>9 : 1) mannosylation of OH-2 of mannosides using a straightforward perbenzylthioglycoside donor has allowed ready assembly of beta-mannosyl oligosaccharides including the repeating trisaccharide motif of the O5 antigen of pathogen Klebsiella pneumoniae.
authors.affiliation: Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford, UK.
authors.forename: Katie J
authors.initials: KJ
authors.lastname: Doores
authors.forename: Benjamin G
authors.initials: BG
authors.lastname: Davis
mesh_terms: D002236:Carbohydrate Conformation; D006878:Hydroxides / Q000737:chemistry*; D008362:Mannosides / Q000737:chemistry*; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013865:Thioglycosides / Q000737:chemistry
chemical_list: D006878:Hydroxides; D008362:Mannosides; D009844:Oligosaccharides; D013865:Thioglycosides; C031356:hydroxide ion