title: Do substance type and diagnosis make a difference? A study of remission from alcohol- versus drug-use disorders using the National Epidemiologic Survey on Alcohol and Related Conditions.
abstract: OBJECTIVE
  This study examined rates of remission from substance-use disorders based on type of disorder (abuse vs dependence), type of substance (alcohol vs other drug), and polysubstance involvement (alcohol or drug vs alcohol and drug).
  
  
  METHODS
  Participants in the National Epidemiologic Survey on Alcohol and Related Conditions were included if they met criteria for a prior-to-past-year alcohol- and/ or drug-use disorder (N = 12,297). Odds ratios were computed to examine differences in the rate of remission as of the past year.
  
  
  RESULTS
  Individuals with a prior-to-past-year diagnosis of abuse were more likely to be remitted, compared with those with a diagnosis of dependence. Individuals with both prior-to-past-year alcohol- and drug-use disorders were less likely to be remitted, compared with those with only an alcohol- or drug-use disorder. No differences were observed in remission rates comparing individuals with a prior-to-past-year alcohol-use disorder with those with a drug-use disorder.
  
  
  CONCLUSIONS
  The findings support prior research in suggesting a worse prognosis for individuals with a diagnosis of dependence and problematic use of both alcohol and drugs. In contrast with results from treatment samples, these general population data indicate that alcohol-use and drug-use disorders have a similar prognosis.
authors.affiliation: University of California, Los Angeles, Integrated Substance Abuse Programs, 11075 Santa Monica Boulevard, Suite 200, Los Angeles, California 90025, USA. karno@ucla.edu
authors.forename: Mitchell P
authors.initials: MP
authors.lastname: Karno
authors.forename: Christine E
authors.initials: CE
authors.lastname: Grella
authors.forename: Noosha
authors.initials: N
authors.lastname: Niv
authors.forename: Umme
authors.initials: U
authors.lastname: Warda
authors.forename: Alison A
authors.initials: AA
authors.lastname: Moore
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000175:diagnosis / Q000453:epidemiology / Q000534:rehabilitation*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D013287:Illicit Drugs; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000534:rehabilitation*; D013695:Temperance; D014481:United States
chemical_list: D013287:Illicit Drugs