Ear, nose and throat manifestations of Behçet's disease: a review.
OBJECTIVE
To review Behçet's disease and to describe its clinical features in the head, neck and upper respiratory tract.


METHODS
A literature review was undertaken, following a Medline search of publications over a 30-year period, and utilising the expert knowledge of one of the authors (RJM) with a specialist interest in Behçet's disease.


RESULTS
Twenty-seven articles with ENT relevance were obtained. Otorhinolaryngological manifestations included symptoms and signs in the mouth, nose, sinus, larynx and ear.


CONCLUSIONS
Behçet's disease is usually considered to be a condition affecting the oral cavity, eyes and genitals. This article shows that most patients will also exhibit other ENT symptoms, hearing loss in particular. Indeed, Behçet's disease may present with features other than the classic triad of symptoms. Raised awareness of the clinical features within the head and neck region will hopefully enable early diagnosis and treatment of this potentially serious condition.
Webb
C J
CJ
Department of Otorhinolaryngology, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK.
Moots
R J
RJ
Swift
A C
AC
D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D015235:HLA-B Antigens / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D019226:Oral Ulcer / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D010038:Otorhinolaryngologic Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D012120:Respiration Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D013256:Steroids / Q000627:therapeutic use; D014456:Ulcer / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology
D015235:HLA-B Antigens; D007166:Immunosuppressive Agents; D013256:Steroids