title: Copper-mediated C-H bond arylation of arenes with arylboronic acids.
abstract: A new copper-mediated cross-coupling of arenes and arylboronic acids is described. Under the influence of Cu(OCOCF 3) 2, the C-H bond arylation of electron-rich arenes with arylboronic acids takes place to afford a range of biaryls in good yields. The reaction is selective for cross-coupling; no homocoupling product arising from arenes or arylboronic acids is detected. Multiple C-H bond arylation is possible with indoles and pyrroles furnishing interesting extended pi-systems.
authors.affiliation: Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
authors.forename: Ikuya
authors.initials: I
authors.lastname: Ban
authors.forename: Tomoko
authors.initials: T
authors.lastname: Sudo
authors.forename: Tadashi
authors.initials: T
authors.lastname: Taniguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D006841:Hydrocarbons, Aromatic; D009942:Organometallic Compounds; D003300:Copper