Surface topography of zirconia implants does not alter action potentials of isolated rat sciatic nerves.
The purpose of this study was to explore the effects of airborne-particle abrasion and selective infiltration etching of a yttrium-partially stabilized tetragonal zirconia polycrystal (Y-TZP) implant surfaces on nerve conduction. Particle-abraded Y-TZP (P/Y-TZP), selective infiltration etched Y-TZP (SIE/Y-TZP), and commercially pure titanium (CP-Ti) were used in the study (n = 5).The compound action potentials of the right and left sciatic nerves of eight sacrificed rats were quantified at the in vitro level. The implants were brought into intimate contact with the nerves and the time required for initiation of compound action potentials (TcAP), depolarization (Dp), repolarization (Rp), and amplitude of evoked compound action potentials (cAPs) were recorded before and after contact with the implants. The difference in cAPs between the basal response and after contact with CP-Ti implant was significant (p < 0.05). Time-dependent changes in cAPs of P/Y-TZP and SIE/Y-TZP groups and their basal nerve responses were similar (p > 0.05). Within- and between-subject comparisons revealed that TcAP, Dp, and Rp values for all groups were similar (p > 0.05). Particle-abraded and selective infiltration-etched zirconia implant surfaces do not alter nerve conduction beyond physiologic limits.
Ertan
Ahmet Atila
AA
Department of Prosthodontics, Faculty of Dentistry, Hacettepe University, 06100 Sihhiye, Ankara, Turkey.
Celebi
Nilüfer
N
Bayolken
Merve
M
Onur
Mehmet Ali
MA
Aboushelib
Moustafa Nabil
MN
Feilzer
Albert
A
Cehreli
Murat
M
D000200:Action Potentials; D000818:Animals; D002478:Cells, Cultured; D008297:Male; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D019736:Prostheses and Implants; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000187:drug effects / Q000473:pathology*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D015040:Zirconium / Q000737:chemistry*
D015040:Zirconium; D014025:Titanium