title: Blood cells contribute to glial repair in an insect.
abstract: Using antibodies specific for haemocytes, we have shown that these blood cells penetrate the abdominal nervous connectives of the cockroach following selective disruption of the glia using the DNA-intercalating drug, ethidium bromide, as a glial toxin. Within 4 days post-lesion, the labelled cells formed a mosaic beneath the neural lamella and penetrated deeply among the disrupted subperineurial glia. These observations confirm that exogenous cells are involved in glial repair and support a previous hypothesis that they play critical roles in both structural repair and the recruitment of endogenous reactive cells.
authors.affiliation: Zoology Department, University College, London WC1E 6BT, U.K.
authors.forename: E A
authors.initials: EA
authors.lastname: Howes
authors.forename: B M
authors.initials: BM
authors.lastname: Chain
authors.forename: P J
authors.initials: PJ
authors.lastname: Smith
authors.forename: J E
authors.initials: JE
authors.lastname: Treherne