title: Effect of silica precursors-type on mechanical properties of sol-gel coatings.
abstract: Reversion to narrowing, called restenosis, still remains an important problem of coronary angioplasty. Analysis of the problem revealed that the application of surface layers aimed at creating on the stent surface a neutral barrier between its metallic framework and tissues of the blood-vascular system is decidedly best to impede the restenosis. They also play the role of medicine carriers. This article presents a new sol-gel technology, to be applied in coronary stent coatings. Currently, this is one of the most progressive methods allowing the modification of surface layers of metallic biomaterials. The results presented prove that due to a proper selection of silica precursors it is possible to obtain continuous, smooth, plastic deformation-resistant sol-gel coatings, which additionally are characterised by very close adherence to the base material, nanometer thickness and low degree of surface development.
authors.affiliation: Institute of Materials Science and Applied Mechanics, Wrocław University of Technology, Poland. dominika.grygier@pwr.wroc.pl
authors.forename: Dominika
authors.initials: D
authors.lastname: Grygier
authors.forename: Włodzimierz
authors.initials: W
authors.lastname: Dudziński
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Wiktorczyk
authors.forename: Krystyna
authors.initials: K
authors.lastname: Haimann
mesh_terms: D000497:Alloys / Q000138:chemical synthesis / Q000627:therapeutic use; D002516:Ceramics / Q000138:chemical synthesis / Q000627:therapeutic use; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000627:therapeutic use; D023903:Coronary Restenosis / Q000517:prevention & control; D019544:Equipment Failure Analysis; D005782:Gels / Q000138:chemical synthesis / Q000627:therapeutic use*; D006801:Humans; D008422:Materials Testing; D044367:Phase Transition; D012822:Silicon Dioxide / Q000737:chemistry* / Q000627:therapeutic use; D015607:Stents / Q000009:adverse effects / Q000592:standards; D013499:Surface Properties
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D005782:Gels; D012822:Silicon Dioxide