Phosphate starvation signaling: a threesome controls systemic P(i) homeostasis.
Systemic signaling between roots and shoots is required to maintain mineral nutrient homeostasis for optimal metabolism under varying environmental conditions. Recent work has revealed molecular components of a signaling module that controls systemic phosphate homeostasis, modulates uptake and transport in Arabidopsis. This module comprises PHO2, a protein that controls protein stability, the phloem-mobile microRNA-399 and a ribo-regulator that squelches the activity of miR399 towards PHO2 by a novel mechanism. This advance is a significant step for the design of future rational approaches to improve crop phosphate use efficiency.
Doerner
Peter
P
Institute of Molecular Plant Science, School of Biological Sciences, Daniel Rutherford Building, King's Buildings, University of Edinburgh, Edinburgh EH9 3JH, Scotland, United Kingdom. Peter.Doerner@ed.ac.uk
D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000502:physiology; D006706:Homeostasis; D035683:MicroRNAs / Q000502:physiology; D008954:Models, Biological; D010710:Phosphates / Q000378:metabolism*; D022661:RNA, Untranslated / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D044763:Ubiquitin-Conjugating Enzymes / Q000502:physiology
D029681:Arabidopsis Proteins; D035683:MicroRNAs; D010710:Phosphates; D022661:RNA, Untranslated; C514696:UBC24 protein, Arabidopsis; D044763:Ubiquitin-Conjugating Enzymes