title: Time-suppression test using a colorimetric probe (alamarBlue) that measures bacterial metabolic activity.
abstract: We developed a time-suppression test using alamarBlue, which will allow estimation of the cidal or static nature of antimicrobials very easily and quickly. As an example, the effects of vancomycin, linezolid, and daptomycin on a representative strain of Staphylococcus aureus were estimated.
authors.affiliation: Department of Pediatrics, Juntendo University, Tokyo, Japan.
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Komatsu
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tajima
authors.forename: Teruyo
authors.initials: T
authors.lastname: Ito
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Yamashiro
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hiramatsu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003124:Colorimetry; D010078:Oxazines; D013211:Staphylococcus aureus / Q000187:drug effects / Q000378:metabolism*; D014966:Xanthenes
chemical_list: D000900:Anti-Bacterial Agents; D010078:Oxazines; D014966:Xanthenes; C005843:resazurin