title: Biatrial myxoma and cerebral ischemia successfully treated with intravenous thrombolytic therapy and surgical resection.
abstract: We report what we believe is the 1st case in the medical literature in which an intravenous thrombolytic agent was used successfully--without massive intracranial bleeding--to treat acute stroke induced by atrial myxoma. Our patient, who had biatrial myxomas with a dual blood supply from the right coronary artery, presented with cerebral ischemia. Transesophageal echocardiography was essential in clarifying the diagnosis and in helping to direct surgical treatment.
authors.affiliation: Department of Internal Medicine, Division of Cardiology, and Department of Neurology at the University of Texas Health Science Center Medical School at Houston, Houston, Texas 77030, USA. Morhaf.Ibrahim@uth.tmc.edu
authors.forename: Morhaf
authors.initials: M
authors.lastname: Ibrahim
authors.forename: Cezar
authors.initials: C
authors.lastname: Iliescu
authors.forename: Hazim J
authors.initials: HJ
authors.lastname: Safi
authors.forename: Maximilian L
authors.initials: ML
authors.lastname: Buja
authors.forename: David D
authors.initials: DD
authors.lastname: McPherson
authors.forename: Francisco
authors.initials: F
authors.lastname: Fuentes
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006325:Heart Atria; D006338:Heart Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000473:pathology / Q000601:surgery*; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator