Rearrangement of N,N-di-tert-butoxycarbonylpyridin-4-amines and formation of polyfunctional pyridines.
N, N-Di-tert-butoxycarbonylpyridin-4-amines were found to be rearranged to tert-butyl 4-(tert-butoxycarbonylamino)nicotinates by treatment with LDA in THF.
Liu
Yahua
Y
Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA.
Ding
Qiang
Q
Wu
Xu
X
D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
D000588:Amines; D002264:Carboxylic Acids; D011725:Pyridines; D010100:Oxygen