[Effects of different intensity pulsed electromagnetic fields on serum estradiol of ovariectomized rats].
OBJECTIVE
To explore the effects of different intensity pulsed electromagnetic fields (PEMFs) on serum estradiol in ovariectomized rats.


METHODS
Fifty female SD rats were randomly divided into five groups: sham-operated control (no PEMF treatment), ovariectomized control(no PEMF treatment),ovariectomized group I, II, III (PEMF treatment at 8 Hz frequency and 0.77 mT, 3.82 mT, 9.87 mT intensity, 40 min daily for 30 days). Except for the sham-operated control rats, a standardized ovariectomy was used on every rat of other groups. The serum estradiol(E2) of rats was assessed at 30 days after PEMF treatment.


RESULTS
The E2 values of the SHAM control group were significantly higher than those of other four groups (P < 0.05 or P < 0.01), but the difference in E2 values was not significant among the other four groups (P > 0.05).


CONCLUSIONS
PEMFs can not improve the serum estradiol level of ovariectomized rat, it shows that the therapeutical effect of PEMFs is not due to improve the serum estradiol level.
Yang
Yong-Hong
YH
Department of Rehabilitation, West China Hospital, Sichuan University, Chengdu 610041, China.
He
Cheng-Qia
CQ
Yang
Lin
L
Wang
Wei
W
Lei
Zhong-Jie
ZJ
D000818:Animals; D004574:Electromagnetic Fields; D004958:Estradiol / Q000097:blood*; D005260:Female; D010052:Ovariectomy; D051381:Rats; D017207:Rats, Sprague-Dawley
D004958:Estradiol