title: Synthesis of 4a-carba-alpha-D-lyxofuranose from 2,3-O-isopropylidene-L-erythruronolactone via Tebbe-mediated cascade reaction.
abstract: A new, efficient and highly diastereoselective approach for the synthesis of 1,2,3,5-tetraacetylcarba-alpha-D-lyxofuranose from D-ribose is reported via one-pot conversion of to using Tebbe reagent which involves a cascade reaction sequence of methylenation, cleavage of isopropyl group, carbocyclization and again methylenation.
authors.affiliation: Organic Division III, Indian Institute of Chemical Technology, Hyderabad, India.
authors.forename: Girija
authors.initials: G
authors.lastname: Prasad Mishra
authors.forename: G
authors.initials: G
authors.lastname: Venkata Ramana
authors.forename: B
authors.initials: B
authors.lastname: Venkateswara Rao
mesh_terms: D054329:Carbasugars / Q000138:chemical synthesis*; D007783:Lactones / Q000737:chemistry*; D009005:Monosaccharides / Q000737:chemistry*
chemical_list: C531504:2,3-O-isopropylidene-L-erythruronolactone; C531503:4a-carba-alpha-D-lyxofuranose; D054329:Carbasugars; D007783:Lactones; D009005:Monosaccharides