Cyano-bridged coordination polymer nanoparticles with high nuclear relaxivity: toward new contrast agents for MRI.
New water-soluble paramagnetic Gd-containing cyano-bridged metallic coordination polymer nanoparticles with a chitosan shell show high nuclear relaxivity in acidic water which is up to six times higher than that of the actually used Gd-chelates.
Guari
Yannick
Y
Institut Charles Gerhardt Montpellier, UMR 5253, Chimie Moléculaire et Organisation du Solide, Université Montpellier II, Place E. Bataillon, 34095 Montpellier cedex 5, France.
Larionova
Joulia
J
Corti
Maurizio
M
Lascialfari
Alessandro
A
Marinone
Massimo
M
Poletti
Giulio
G
Molvinger
Karine
K
Guérin
Christian
C
D003287:Contrast Media / Q000737:chemistry*; D005682:Gadolinium / Q000737:chemistry; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013696:Temperature; D014867:Water / Q000737:chemistry
D003287:Contrast Media; D009570:Nitriles; D011108:Polymers; D014867:Water; D005682:Gadolinium