Multiple seizures after bupropion overdose in a small child.
Unintentional ingestion of bupropion in young children has generally resulted in limited toxicity. We report a case of pediatric bupropion ingestion resulting in multiple seizures. The patient experienced hallucinations, agitation, vomiting, tachycardia and seizures after ingestion of 1050 (48 mg/kg) of extended-release bupropion. The potential for severe toxicity in the setting of pediatric overdose should be recognized.
Spiller
Henry A
HA
Kentucky Regional Poison Center, Louisville, KY 40232-5070, USA. henry.spiller@nortonhealthcare.org
Schaeffer
Scott E
SE
D018687:Antidepressive Agents, Second-Generation / Q000506:poisoning*; D016642:Bupropion / Q000506:poisoning*; D002648:Child; D062787:Drug Overdose; D004636:Emergency Service, Hospital; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D008297:Male; D012640:Seizures / Q000139:chemically induced* / Q000188:drug therapy
D018687:Antidepressive Agents, Second-Generation; D016642:Bupropion