title: Neutralization of lethality and proteolytic activities of Malayan pit viper (Calloselasma rhodostoma) venom with North American Virginia opossum (Didelphis virginiana) serum.
abstract: Malayan pit viper (Calloselasma rhodostoma) envenomation is a major health problem in South East Asia. During envenomation, venom components mainly affect the hemostatic system. The sera from the North American Virginia opossums (Didelphis virginiana) were able to neutralize the venom of the Malayan pit viper. These natural inhibitors could be explored as potential therapeutics against envenomations of a variety of venomous snake species in different geographical habitats.
authors.affiliation: Program of Biotechnology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Piboon
authors.initials: P
authors.lastname: Pornmanee
authors.forename: Elda E
authors.initials: EE
authors.lastname: Sánchez
authors.forename: Gonzalo
authors.initials: G
authors.lastname: López
authors.forename: Amorn
authors.initials: A
authors.lastname: Petsom
authors.forename: Orawan
authors.initials: O
authors.lastname: Khow
authors.forename: Narumol
authors.initials: N
authors.lastname: Pakmanee
authors.forename: Lawan
authors.initials: L
authors.lastname: Chanhome
authors.forename: Polkit
authors.initials: P
authors.lastname: Sangvanich
authors.forename: John C
authors.initials: JC
authors.lastname: Pérez
mesh_terms: D000818:Animals; D003435:Crotalid Venoms / Q000037:antagonists & inhibitors*; D048293:Didelphis / Q000097:blood*; D007928:Lethal Dose 50
chemical_list: D003435:Crotalid Venoms