[Pathogenesis of insulin resistance in different endocrinopathies].
Visceral obesity, insulin resistance and increased cardiovascular morbidity and mortality are strongly related. Development of visceral obesity and regulation of body fat distribution in general are influenced by many factors. This article is a summary of current knowledge about pathogenesis of insulin resistance in different endocrinopathies, particularly in the Cushing's syndrome and acromegaly, as they are both connected with the pathological conditions mentioned above.
Durovcová
V
V
III. interní klinika 1. lékarské fakulty UK a VFN Praha. viktoria.durovcova@gmail.com
Krsek
M
M
Haluzík
M
M
D004700:Endocrine System Diseases / Q000503:physiopathology*; D013006:Growth Hormone / Q000502:physiology; D006728:Hormones / Q000502:physiology; D006801:Humans; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism; D007333:Insulin Resistance / Q000502:physiology*; D050152:Intra-Abdominal Fat / Q000378:metabolism; D011965:Receptors, Glucocorticoid / Q000502:physiology
D006728:Hormones; D011965:Receptors, Glucocorticoid; D013006:Growth Hormone; D006913:Hydroxysteroid Dehydrogenases