title: Ontology for genome comparison and genomic rearrangements.
abstract: We present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further automated analysis can be built. The nomenclature defined by the ontology will foster clearer communication between biologists, and also standardize terms used by data publishers in the results of analysis programs. The overriding aim of this ontology is the facilitation of consistent annotation of genomes through computational methods, rather than human annotators. To this end, the ontology includes definitions that support computer analysis and automated transfer of annotations between genomes, rather than relying upon human mediation.
authors.affiliation: School of Computing Science, University of Newcastle upon Tyne, Claremont Tower, Claremont Road, Newcastle upon Tyne NE1 7RU, UK.
authors.forename: Keith
authors.initials: K
authors.lastname: Flanagan
authors.forename: Robert
authors.initials: R
authors.lastname: Stevens
authors.forename: Matthew
authors.initials: M
authors.lastname: Pocock
authors.forename: Pete
authors.initials: P
authors.lastname: Lee
authors.forename: Anil
authors.initials: A
authors.lastname: Wipat