title: [Assesment of real optoelectronic method in the detection of cervical intraepithelial neoplasia].
abstract: BACKGROUND
  Biophysics is becoming an important factor in prevention of cervical cancer. One of the most promising concepts of biophysical program for the prevention of cervical cancer is the optoelectronic method--Truscreen.
  
  
  OBJECTIVE
  The objective of the work was to determine the usefulness of the real optoelectronic device in the detection of cervical intraepithelial neoplasia
  
  
  METHODS
  From August 2006 till September 2007, 147 patients were examined in the Laboratory of Pathophysiology of Uterine Cervix in Gynecology and Obstetrics Clinical Hospital of Karol Marcinkowski University of Medical Sciences. The study reports prospective, blind trial. The following diagnostic examinations were carried out: examination with the use of optoelectronic method, DNA HPV HIGH RISK test, colposcopy examination and histopatologic biopsy.
  
  
  RESULTS
  The specificity of the optoelectronic method for positive diagnoses amounted to 84%. The sensitivity for intraephitelial changes (CIN 1, CIN 2) was estimated at 53%, and for severe grades (CIN 3, Carcinoma planoepitheliale) at 80%.
  
  
  CONCLUSIONS
  Optoelectronic diagnostics is useful in the detection of cervical neoplastic changes. The optoelectronic method may prove to be a significant diagnostic device at the basic and advanced level of cervical screening. The advantage of the optoelectronic method over prevention based on cytodiagnostics and colposcopy, includes the immediate result of the examination and its automation as well as standardization.
authors.affiliation: Klinika Onkologii Ginekologicznej, Katedra Ginekologii, Połoznictwa i Onkologii Ginekologicznej UM im. K. Marcinkowskiego w Poznaniu. pruski@oxytop.pl
authors.forename: Dominik
authors.initials: D
authors.lastname: Pruski
authors.forename: Witold
authors.initials: W
authors.lastname: Kedzia
authors.forename: Marcin
authors.initials: M
authors.lastname: Przybylski
authors.forename: Agata
authors.initials: A
authors.lastname: Józefiak
authors.forename: Helena
authors.initials: H
authors.lastname: Kedzia
authors.forename: Marek
authors.initials: M
authors.lastname: Spaczyński
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000473:pathology*; D003127:Colposcopy; D004279:DNA, Viral / Q000032:analysis*; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D008875:Middle Aged; D055095:Optics and Photonics; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000473:pathology; D011044:Poland; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D014626:Vaginal Smears / Q000295:instrumentation* / Q000379:methods*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000473:pathology
chemical_list: D004279:DNA, Viral