Eosinophilic angiocentric fibrosis of the sinonasal tract.
Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory fibrosing lesion of the upper respiratory tract and orbit that occurs mainly in young to middle-aged women. The etiology of EAF is unknown. To our knowledge, approximately 28 cases have been previously reported in the English literature. We report here 3 additional cases of EAF of the sinonasal tract; 2 in women aged 19 and 31 years, and 1 in a man aged 49 years. The 19-year-old woman is the youngest patient with EAF ever described. The patients presented with a nasal cavity mass, face pain, or nasal obstructive symptoms of long duration.
Kosarac
Ognjen
O
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA.
Luna
Mario A
MA
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
Ro
Jae Y
JY
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA.
Ayala
Alberto G
AG
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA. Electronic address: aayala@tmh.tmc.edu.
D000328:Adult; D004802:Eosinophilia / Q000473:pathology*; D005157:Facial Pain / Q000473:pathology; D005260:Female; D005355:Fibrosis; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology; D015508:Nasal Obstruction / Q000209:etiology* / Q000473:pathology*; D009300:Nasal Septum / Q000473:pathology