title: Long term outcome after balloon angioplasty and stenting of subclavian artery obstruction: a single centre experience.
abstract: BACKGROUND
  Percutaneous transluminal angioplasty is an accepted and successful treatment strategy in obstructive disease of the subclavian artery. The purpose of this study was to evaluate the technical and clinical long-term outcome following endovascular therapy.
  
  
  METHODS
  We retrospectively analyzed 99 patients (mean age of 65 +/- 10 years) with 100 interventions of the subclavian arteries and the brachiocephalic trunk with different aetiologies [atherosclerosis (90%); Takayasu's arteritis (5%); thromboembolism (2%); external compression (1%); iatrogenic dissection (1%) and occlusion after graft implantation in type B dissection (1%)].
  
  
  RESULTS
  Primary success rate was 97% (100% for stenoses and 90% for total occlusions). Treatment modalities included balloon angioplasty (PTA) alone (16%), stent implantation (78%), rotational thrombectomy (2%) and atherectomy (1%). The primary 1-year patency rate of the whole study cohort was 87% being not significantly lower after PTA (75%) compared to stent assisted angioplasty (89%). After thrombectomy and atherectomy no relevant restenosis were found. Multivariable analysis of 1-year restenosis-free survival revealed younger age (p = 0.03) and stenting (p = 0.04) as independent predictor. The blood pressure difference between both limbs at baseline was 42 +/- 24 mmHg and dropped to 10 +/- 14 mmHg after the intervention and 15 +/- 20 mmHg after 12 months, respectively (p = 0.01).
  
  
  CONCLUSIONS
  Endovascular therapy of subclavian artery obstructions of various aetiologies offers good acute success rates even in total occlusions. Long-term patency rate is in favour of stent placement.
authors.affiliation: Department of Angiology, Heart Centre Bad Krozingen, Bad Krozingen, Germany. sebastian.sixt@herzzentrum.de
authors.forename: S
authors.initials: S
authors.lastname: Sixt
authors.forename: A
authors.initials: A
authors.lastname: Rastan
authors.forename: U
authors.initials: U
authors.lastname: Schwarzwälder
authors.forename: T
authors.initials: T
authors.lastname: Schwarz
authors.forename: E
authors.initials: E
authors.lastname: Norry
authors.forename: U
authors.initials: U
authors.lastname: Frank
authors.forename: C
authors.initials: C
authors.lastname: Müller
authors.forename: U
authors.initials: U
authors.lastname: Beschorner
authors.forename: K
authors.initials: K
authors.lastname: Bürgelin
authors.forename: T
authors.initials: T
authors.lastname: Nazary
authors.forename: K
authors.initials: K
authors.lastname: Hauswald
authors.forename: M
authors.initials: M
authors.lastname: Hauk
authors.forename: F-J
authors.initials: FJ
authors.lastname: Neumann
authors.forename: T
authors.initials: T
authors.lastname: Zeller
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000379:methods*; D001807:Blood Vessel Prosthesis; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D013349:Subclavian Steal Syndrome / Q000601:surgery*; D016896:Treatment Outcome