Nocardiosis in adult-onset Still's disease and vasculitis syndrome.
Four cases of nocardiosis in patients with adult-onset Still disease and vasculitis syndrome are presented. Three patients developed lung abscesses and 1 case developed a brain abscess. All were treated with high-dose corticosteroids, and 3 were given cyclosporine when they developed nocardiosis. All patients were successfully treated with antibiotics; cyclosporine was discontinued in 2 cases. These cases indicate that systemic nocardiosis can develop in patients with various rheumatologic diseases who are treated with corticosteroid and immunosuppressive drugs such as cyclosporine.
Tada
Yoshifumi
Y
Department of Internal Medicine, Saga Medical School, Saga, Japan. taday@cc.saga-u.ac.jp
Fukuoka
Mami
M
Mitamura
Mio
M
Koarada
Shuichi
S
Suematsu
Rie
R
Inoue
Hisako
H
Ohta
Akihide
A
Nagasawa
Kohei
K
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D001922:Brain Abscess / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D016572:Cyclosporine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008169:Lung Abscess / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D009617:Nocardia Infections / Q000150:complications*; D016706:Still's Disease, Adult-Onset / Q000150:complications*; D014057:Tomography, X-Ray Computed; D014657:Vasculitis / Q000150:complications*
D000305:Adrenal Cortex Hormones; D016572:Cyclosporine