Reorganization of sleep architecture after surgery for OSAHS.
CONCLUSIONS
Genioglossus advancement and hyoid suspension (GAHM) plus uvulopalatopharyngoplasty (UPPP) can decrease the apnea hypopnea index (AHI) and arousal index, especially respiratory-related arousals. Correspondingly, sleep architecture is reorganized, which is expressed postoperatively as an increase in slow wave sleep and a decrease in lighter sleep.


OBJECTIVE
To explore the reorganization of sleep patterns after GAHM plus UPPP for severe obstructive sleep apnea hypopnea syndrome (OSAHS).


METHODS
GAHM plus UPPP was performed on 31 patients with severe OSAHS (AHI > 40). The postoperative follow-up was 6 months.


RESULTS
The AHI was reduced from 65.93 +/- 23.83 preoperatively to 28.58 +/- 29.11 postoperatively. The arousal index was reduced from 56.00 +/- 18.78 to 41.97 +/- 20.73, and the respiratory arousal index was reduced from 35.44 +/- 21.57 to 22.63 +/- 21.99. No significant change was seen in the spontaneous arousal index (preoperative, 20.56 +/- 12.97; postoperative, 19.34 +/- 10.29). The percentage of REM sleep during the total sleep time (TST) increased from 10.53 +/- 9.13% to 13.92 +/- 6.76%, and the S3 + S4 percentage of TST increased from 3.07 +/- 3.01% to 7.09 +/- 6.83%. Correspondingly, the S1 + S2 percentage of TST decreased from 86.53 +/- 9.28% to 78.89 8.89%.
Sun
Xiaoqiang
X
Department of Otolaryngology, Affiliated Sixth People's Hospital of Shanghai Jiao Tong University, Otolaryngology Institute of Shanghai Jiao Tong University, China.
Yi
Hongliang
H
Cao
Zhenyu
Z
Yin
Shankai
S
D000328:Adult; D000368:Aged; D001143:Arousal; D006801:Humans; D006928:Hyoid Bone / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D017286:Polysomnography; D012890:Sleep; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology / Q000601:surgery*; D012894:Sleep Stages; D012895:Sleep, REM; D014059:Tongue / Q000601:surgery; D014609:Uvula / Q000601:surgery