4-phenyldiazenyl 2-(phenylimino methyl) phenols; synthesis and in-vitro biological evaluation as potential antibacterial agents.
A new series of 4-phenyldiazenyl 2-(phenylimino methyl) phenols were synthesized by the condensation of 5-[(2-chloro phenyl) diazenyl] 2-hydroxybenzaldehyde with different substituted aromatic amines and sulphonamides. All the synthesized compounds were screened in-vitro for their antibacterial activity against different human pathogens viz: B. anthracis, E.coli, S. aureus, S. typhimurium, and P. aeruginosa using disk diffusion assay. All the compounds exhibited considerable inhibition against the bacteria tested.
Halve
Anand K
AK
School of Studies in Chemistry, Jiwaji University Gwalior - 474011, India. halveanand@yahoo.co.in
Dubey
Pushp Kant
PK
Kankoriya
Amit
A
Tiwari
Kiran
K
D000588:Amines; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D052978:Disk Diffusion Antimicrobial Tests; D006801:Humans; D010636:Phenols / Q000138:chemical synthesis* / Q000494:pharmacology; D013449:Sulfonamides
D000588:Amines; D000900:Anti-Bacterial Agents; D010636:Phenols; D013449:Sulfonamides