Disseminated Trichosporon inkin and Histoplasma capsulatum in a patient with newly diagnosed AIDS.
Histoplasma capsulatum and Trichosporon inkin may cause disseminated disease in immunocompromised patients. Disseminated T inkin, the causative agent of white piedra, is rare and difficult to diagnose. We report the case of a 28 year-old man with newly diagnosed HIV infection who developed asymptomatic lesions on his trunk and extremities. Histology demonstrated perivascular and intravascular budding yeasts. Blood cultures revealed fungal organisms that were difficult to culture. Specimens were positive for H capsulatum (confirmed by DNA probe) and T inkin. Compared with disseminated histoplasmosis, disseminated Trichosporon is relatively uncommon. Physicians should be aware of this agent in immunocompromised hosts.
David
Consuelo
C
Department of Dermatology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Martin
Donna Bilu
DB
Deng
April
A
Cooper
Jennifer Z
JZ
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D000328:Adult; D001706:Biopsy; D003881:Dermatomycoses / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006658:Histoplasma; D006660:Histoplasmosis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D014250:Trichosporon