[Effects of electroacupuncture at shu-points of the five zang-organs on electrophysiologic function of sciatic nerve in the rabbit of Guillain-Barre syndrome].
OBJECTIVE
To probe into the mechanism of electroacupuncture at shu-points of the five zang-organs for treatment of Guillain-Barre syndrome (GBS).


METHODS
Eighty healthy giant-ear white rabbits were randomly divided into 4 groups, a blank group, a model group, an electroacupuncture (EA) group and an immunoglobulin group, 20 rabbits in each group. The internationally recognized P 2 immune rabbit model was used in the study. The EA group were treated with EA at shu-points of the five zang-organs and the immunoglobulin group with intravenous injection of immunoglobulin 80 mg/kg/day. The sciatic nerve movement conduction velocity (MCV) and F wave incidence rate were investigated respectively at the 7th and 14th days of treatment in the rabbits of GBS.


RESULTS
The sciatic nerve MCV significantly reduced in the model group, and it significantly increased (P < 0.01) and F wave abnormal cases was significantly reduced (P < 0.05) after treatment for 14 days in the EA group as compared with those in the model group.


CONCLUSIONS
EA at shu-points of the five zang-organs can increase the sciatic nerve MCV and decrease the abnormal F wave incidence rate of the sciatic nerve in the rabbit of GBS.
Wang
Hong-Feng
HF
Changchun University of TCM, Changchun 130117, China. ccwhf@126.com
Dong
Gui-Rong
GR
D015669:Acupuncture Points; D000818:Animals; D015671:Electroacupuncture; D005260:Female; D020275:Guillain-Barre Syndrome / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D009431:Neural Conduction; D011817:Rabbits; D012584:Sciatic Nerve / Q000503:physiopathology*