[A new flavonoid from heartwood of Caesalpinia sappan].
OBJECTIVE
To seek for new active components from Caesalpinia sappan.


METHODS
The chemical constituents were isolated and identified by means of chromatographic and spectroscopic technologies methods.


RESULTS
Nine compounds were isolated, and their structures were identified as 3, 8-dihydroxy4, 10-dimethoxy-7-oxo-[2] benzopyrano[4,3-b] benzopyran (1), 3-deoxysappanchalcone (2), sappanchalcone (3), 3-deoxysappanone B (4), rhamnetin (5), protosappanin C (6), 3, 7-dihydroxy-chroman-4-one (7), dimethyl adipate (8), daucosterin (9).


CONCLUSIONS
Compound 1 was a new compound, and compounds 7, 8 were isolated from this plant for the first time.
Shu
Shi-Hui
SH
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.
Han
Jing-Lan
JL
Du
Guan-Hua
GH
Qin
Hai-Lin
HL
D000818:Animals; D029911:Caesalpinia / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology
C540313:3,8-dihydroxy-4,10-dimethoxy-7-oxo-(2)-benzopyrano(4,3-b)benzopyran; D004365:Drugs, Chinese Herbal; D005419:Flavonoids