MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization.
We present MetaRoute, an efficient search algorithm based on atom mapping rules and path weighting schemes that returns relevant or textbook-like routes between a source and a product metabolite within seconds for genome-scale networks. Its speed allows the algorithm to be used interactively through a web interface to visualize relevant routes and local networks for one or multiple organisms based on data from KEGG.


BACKGROUND
http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute.


BACKGROUND
Supplementary details are available at http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute.
Blum
Torsten
T
Division for Simulation of Biological Systems, ZBIT/WSI, University of Tübingen, Tübingen, Germany. blum@informatik.uni-tuebingen.de
Kohlbacher
Oliver
O
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D030541:Databases, Genetic; D016247:Information Storage and Retrieval; D053858:Metabolic Networks and Pathways; D020543:Proteome / Q000235:genetics / Q000378:metabolism; D012984:Software; D014584:User-Computer Interface
D020543:Proteome