title: Synthesis and biological activity of N-substituted spiro[benzoxazepine-piperidine] Abeta-peptide production inhibitors.
authors.affiliation: Laboratoire de Chimie Biomoléculaire, IBDM-UMR-6216-CNRS, Faculté des Sciences Luminy, Université de Méditerranée, Marseille cedex 9, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Laras
authors.forename: N
authors.initials: N
authors.lastname: Pietrancosta
authors.forename: T
authors.initials: T
authors.lastname: Tomita
authors.forename: T
authors.initials: T
authors.lastname: Iwatsubo
authors.forename: J L
authors.initials: JL
authors.lastname: Kraus
mesh_terms: D016229:Amyloid beta-Peptides / Q000037:antagonists & inhibitors* / Q000378:metabolism; D001381:Azepines / Q000737:chemistry*; D001554:Benzene / Q000737:chemistry*; D002460:Cell Line; D006801:Humans; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D010455:Peptides / Q000378:metabolism*; D010880:Piperidines / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D016229:Amyloid beta-Peptides; D001381:Azepines; D010455:Peptides; D010880:Piperidines; D013141:Spiro Compounds; D001554:Benzene