title: Systemic therapy of paediatric atopic dermatitis: an update.
abstract: Topical therapies are the mainstay in the treatment of atopic dermatitis, and are effective in the majority of patients with mild and localized disease. In patients with widespread or recalcitrant moderate to severe dermatitis, systemic therapies may be required. The frequently used systemic therapies are immunosuppressants, immune response modifiers, anti-inflammatories, antihistamines, and antibiotics. In this article, the indications and scientific support for the use of these medications is reviewed.
authors.affiliation: Department of Dermatology, Royal Children's Hospital, Parkville, Victoria, Australia.
authors.forename: Kate L A
authors.initials: KL
authors.lastname: Borchard
authors.forename: David
authors.initials: D
authors.lastname: Orchard
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D005228:Fatty Acids, Essential / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008516:Medicine, Chinese Traditional; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use; D010936:Plant Extracts / Q000627:therapeutic use; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D005228:Fatty Acids, Essential; D006634:Histamine H1 Antagonists; D007166:Immunosuppressive Agents; D010726:Phosphodiesterase Inhibitors; D010936:Plant Extracts