title: Mesojejunoileac liposarcoma with intrahepatic metastasis in a dog.
abstract: We report a liposarcoma at the mesojejunoileum that was widely excised, and then the intrahepatic metastatic liposarcoma was found. The dog was treated by two single-agent chemotherapy separately. The patient was an 8-year-old, male Dachshund, and was referred to our hospital owing to the significant distention of the left abdomen. Neither radiography nor ultrasonography detected the actual association of the tumor with the abdominal viscera before surgery. A large-sized tumor mass that adhered to the mesojejunoileum was explored by laparatomy. Final diagnosis of a pleomorphic liposarcoma was made by the routine histology and further identified by Oil Red O stain. The two single-agent chemotherapy including doxorubicin followed by capecitabine, however, failed to cause remission of the intrahepatic metastatic lesions. The patient died 22 months after operation and the cause of death was supposed to be metastatic liposarcoma.
authors.affiliation: Department of Veterinary Medicine, and Veterinary Medical Teaching Hospital, Graduate Institute of Veterinary Pathology, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
authors.forename: Shih-Chieh
authors.initials: SC
authors.lastname: Chang
authors.forename: Jiunn-Wang
authors.initials: JW
authors.lastname: Liao
mesh_terms: D000818:Animals; D000069287:Capecitabine; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D004285:Dogs; D004317:Doxorubicin / Q000627:therapeutic use; D017809:Fatal Outcome; D005472:Fluorouracil / Q000031:analogs & derivatives / Q000627:therapeutic use; D007078:Ileal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D007580:Jejunal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D007813:Laparotomy / Q000662:veterinary; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000662:veterinary*; D011859:Radiography
chemical_list: D003841:Deoxycytidine; D000069287:Capecitabine; D004317:Doxorubicin; D005472:Fluorouracil