title: Human interferon does not protect cowpea plant cell protoplasts against infection with alfalfa mosaic virus.
abstract: Orchansky et al. (P. Orchansky, M. Rubenstein, and I. Sela), Proc. Natl. Acad. Sci. USA 79, 2278-2280, 1982) reported that natural and recombinant human interferon (HuIFN), e.g., HuIFN-beta and -alpha subspecies gamma3, protects plant cells from infection with a plant virus (tobacco mosaic virus). For their study they used tobacco leaf discs as well as tobacco protoplasts. It is now reported that recombinant HuIFN-beta and HuIFN-alpha2 do not significantly decrease alfalfa mosaic virus increase in cowpea mesophyll protoplasts.
authors.affiliation: Department of Biochemistry, State University of Leiden, P.O. Box 9505, 2300 RA Leiden, The Netherlands.
authors.forename: M J
authors.initials: MJ
authors.lastname: Huisman
authors.forename: H J
authors.initials: HJ
authors.lastname: Broxterman
authors.forename: H
authors.initials: H
authors.lastname: Schellekens
authors.forename: L
authors.initials: L
authors.lastname: van Vloten-Doting