Modification of second cancer risk after malignant melanoma by parental history of cancer.
The Swedish Family-Cancer Database was used to quantify the incidence of second tumours in melanoma patients with a parental history of cancer. Patients with parents affected by melanoma showed a 32.3-fold risk of second primary melanomas, which was greater than a multiplicative interaction.
Zhang
H
H
Division of Molecular Genetic Epidemiology, German Cancer Research Center, DKFZ, Heidelberg, Germany.
Bermejo
J Lorenzo
JL
Sundquist
J
J
Hemminki
K
K
D000328:Adult; D000368:Aged; D015331:Cohort Studies; D006801:Humans; D008487:Medical History Taking; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D010290:Parents; D012189:Retrospective Studies; D012307:Risk Factors; D012878:Skin Neoplasms / Q000473:pathology*; D013548:Sweden / Q000453:epidemiology