Recipient age and pulsatility index affect uterine receptivity in oocyte donation programmes.
Successful embryo implantation depends on interactions between the embryo and the uterus. Investigating factors related to the recipients in an oocyte donation programme could therefore improve the overall pregnancy outcome. In this study, the factors that affect outcomes following IVF after oocyte donation were evaluated in a retrospective cohort study. A total of 143 cycles were evaluated. All oocyte donors were younger than 30 years of age. In the youngest recipients (< 34 years old) the implantation rate was higher (P = 0.042) and the abortion rate was apparently lower than in the recipients of more advanced age (> or =40 years old). The implantation and pregnancy rates were higher when the pulsatility index was > or = 3.0. The pulsatility index on the day of embryo transfer in oocyte donation IVF cycles was an important determinant of successful pregnancy outcomes.
Huang
Lii-Shung
LS
Institute of Medicine, College of Medicine, Chung-Shan Medical University, Taichung, Taiwan, Republic of China.
Lee
Maw-Sheng
MS
Cheng
En-Hui
EH
Lee
Tsung-Hsien
TH
Liu
Chung-Hsien
CH
Lee
Meng-Chih
MC
Chou
Ming-Chih
MC
D000328:Adult; D000367:Age Factors; D000375:Aging; D010064:Embryo Implantation; D004624:Embryo Transfer; D004717:Endometrium / Q000473:pathology; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D018587:Oocyte Donation; D009865:Oocytes / Q000378:metabolism; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods