Task-dependent semantic interference in language production: an fMRI study.
We used fMRI to investigate competition during language production in two word production tasks: object naming and color naming of achromatic line drawings. Generally, fMRI activation was higher for color naming. The line drawings were followed by a word (the distractor word) that referred to either the object, a related object, or an unrelated object. The effect of the distractor word on the BOLD response was qualitatively different for the two tasks. The activation pattern suggests two different kinds of competition during lexical retrieval: (1) Task-relevant responses (e.g., red in color naming) compete with task-irrelevant responses (i.e., the object's name). This competition effect was dominant in prefrontal cortex. (2) Multiple task-relevant responses (i.e., target word and distractor word) compete for selection. This competition effect was dominant in ventral temporal cortex. This study provides further evidence for the distinct roles of frontal and temporal cortex in language production, while highlighting the effects of competition, albeit from different sources, in both regions.
Spalek
Katharina
K
Center for Cognitive Neuroscience, University of Pennsylvania, USA. katharina.spalek@staff.hu-berlin.de
Thompson-Schill
Sharon L
SL
D000328:Adult; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D010296:Parietal Lobe / Q000033:anatomy & histology / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012660:Semantics; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology; D014705:Verbal Behavior / Q000502:physiology*; D055815:Young Adult