title: Ethnoveterinary use of southern African plants and scientific evaluation of their medicinal properties.
abstract: OBJECTIVE
  Livestock keepers in many developing countries with restricted access to orthodox veterinary healthcare services commonly use traditional remedies to treat their animals when disease is encountered. This review collates the documented use of plants in South Africa for healing various ailments in domestic animals, and records bioactivity testing that has been carried out on these plants.
  
  
  METHODS
  A literature survey was conducted on the use of plants in South African ethnoveterinary medicine (EVM), as well as on biological activity investigations relating to their ethnoveterinary use where available.
  
  
  RESULTS
  The ethnoveterinary application of plants, and results of screening studies of EVM plant extracts in various bioassays is presented. For diseases such as coughs, wounds, skin diseases, mild diarrhoea and reproductive disorders, EVM may be a cheap and easily accessible alternative to expensive pharmaceuticals. Studies on biological activity of EVM plants can provide indications of promising leads for extracts that can be developed into standardized medications to be used on a commercial basis. Isolation studies on active plants may yield pure active compounds that could be chemically modified to optimize medicinal value and reduce possible toxic effects.
  
  
  CONCLUSIONS
  In South Africa, a large proportion of the population relies on traditional remedies to treat themselves and their animals for common diseases. Only a small percentage of EVM plants have been analysed for biological activity or toxic effects, and hence research in this field offers fertile possibilities for future investigation.
authors.affiliation: Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa. lyndy.mcgaw@up.ac.za
authors.forename: L J
authors.initials: LJ
authors.lastname: McGaw
authors.forename: J N
authors.initials: JN
authors.lastname: Eloff
mesh_terms: D000818:Animals; D007202:Indicators and Reagents; D016488:Medicine, African Traditional; D008517:Phytotherapy / Q000662:veterinary*; D010946:Plants, Medicinal / Q000737:chemistry*; D013019:South Africa; D014730:Veterinary Medicine
chemical_list: D007202:Indicators and Reagents