title: Electroencephalographic evaluation of gold wire implants inserted in acupuncture points in dogs with epileptic seizures.
abstract: The purpose of this study was to evaluate both, clinically and with electroencephalographic (EEG) recordings, the effect of gold wire implants in acupuncture points in dogs with uncontrolled idiopathic epileptic seizures. Fifteen dogs with such diagnosis were enrolled in the study. A first EEG recording was performed in all dogs under anaesthesia with xylazine (1mg/kg) and propofol (6 mg/kg) before the treatment protocol, and a second EEG was performed 15 weeks later. Relative frequency power, intrahemispheric coherence available through EEG, number of seizures and seizure severity were compared before and after treatment using a Wilcoxon signed-rank test. There were no significant statistical differences before and after treatment in relative power or in intrahemispheric coherence in the EEG recording. However, there was a significant mean difference in seizure frequency and seizure severity between control and treatment periods. After treatment, nine of the 15 dogs (60%) had at least a 50% reduction in seizures frequency during the 15 weeks established as follow-up of this treatment.
authors.affiliation: Departamento de Fisiología y Farmacología, Facultada de Medicina Veterinaria y Zootecnial, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Delegación Coyoacan, Ciudad de México, C.P. 04510, Mexico.
authors.forename: G
authors.initials: G
authors.lastname: Goiz-Marquez
authors.forename: S
authors.initials: S
authors.lastname: Caballero
authors.forename: H
authors.initials: H
authors.lastname: Solis
authors.forename: C
authors.initials: C
authors.lastname: Rodriguez
authors.forename: H
authors.initials: H
authors.lastname: Sumano
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods / Q000592:standards / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D004285:Dogs; D004569:Electroencephalography / Q000662:veterinary; D004831:Epilepsies, Myoclonic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D005260:Female; D006046:Gold / Q000627:therapeutic use*; D008297:Male; D012640:Seizures / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*
chemical_list: D006046:Gold