title: Designed synthesis of new ortho-carborane derivatives: from mono- to polysubstituted frameworks.
abstract: The use of nucleophilic and electrophilic processes allow the designed synthesis of several B-iodinated derivatives of o-carborane. Because of the straightforward Pd-catalyzed conversion of B-I to B-C bond with Grignard reagents, such as methylMgBr and biPhenylMgBr, both, symmetrical 3,6-R 2-1,2- closo-C 2B 10H 10 and asymmetrical 3-I-6-Me-1,2- closo-C 2B 10H 10 could be obtained. Not only conventional reactions in solution have been studied but also a highly efficient, clean and fast solvent-free procedure has provided successful results to regioselectively produce B-iodinated o-carborane derivatives by a careful control of the reaction conditions. The high number of nonequivalent leaving groups in boron iodinated o-carborane derivatives opens the possibility through B-C coupling to materials with novel possibilities and to self-assembling due to the enhanced polarizability of the C-H bond.
authors.affiliation: Institut de Ciencia de Materials de Barcelona (CSIC) Campus UAB, 08193 Bellaterra, Spain.
authors.forename: Gemma
authors.initials: G
authors.lastname: Barberà
authors.forename: Albert
authors.initials: A
authors.lastname: Vaca
authors.forename: Francesc
authors.initials: F
authors.lastname: Teixidor
authors.forename: Reijo
authors.initials: R
authors.lastname: Sillanpää
authors.forename: Raikko
authors.initials: R
authors.lastname: Kivekäs
authors.forename: Clara
authors.initials: C
authors.lastname: Viñas