Analysis of fat and muscle mass in patients with inflammatory bowel disease during remission and active phase.
Inflammatory bowel disease (IBD) is often associated with malnutrition. The aim of this study was to compare the body composition of outpatients with IBD during remission and active phase. In order to evaluate disease activity we used Crohn's Disease Activity Index for Crohn's disease (CD) patients and Lichtiger's Index for ulcerative colitis (UC) patients. All patients underwent the analysis of BMI, arm muscle area (AMA) and triceps plus subscapula skinfold thickness (TST+SST) to identify total, muscle and fat mass, respectively. In total 102 patients were evaluated (CD, n 50; UC, n 52) and the majority was young women. Malnutrition according to BMI was found in 14.0 % of patients with CD and 5.7 % of UC patients. Muscle mass depletion was detected in more than half of the CD and UC patients. The BMI, TST+SST and AMA values were lower in the active phase only in CD patients (P < 0.05). Fat mass depletion was associated with active phase in both CD and UC patients. Body composition parameters obtained using BMI, TST+SST and AMA were not correlated with the presence of fistula in CD patients (P>0.05). In conclusion, patients without signs of malnutrition had fat mass depletion especially in the active phase and muscle mass depletion occurred both in CD and UC patients.
Rocha
Raquel
R
Department of Sciences of Nutrition, School of Nutrition, Federal University of Bahia, Avenida Araújo Pinho 32, Canela 40110-150, Salvador, Bahia, Brazil. raquelrocha2@yahoo.com.br
Santana
Genoile Oliveira
GO
Almeida
Neogélia
N
Lyra
Andre Castro
AC
D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D000886:Anthropometry / Q000379:methods; D001823:Body Composition; D015992:Body Mass Index; D003093:Colitis, Ulcerative / Q000150:complications / Q000473:pathology*; D003424:Crohn Disease / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000209:etiology / Q000503:physiopathology; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D012008:Recurrence; D012074:Remission Induction; D012720:Severity of Illness Index; D012885:Skinfold Thickness; D055815:Young Adult