Asymmetric multifunctional organocatalytic Michael addition of nitroalkanes to alpha,beta-unsaturated ketones.
Cinchona alkaloid derived primary amine thioureas organocatalyzed Michael addition of nitroalkanes to enones in good yield and up to 98% ee and offered a new way to construct quaternary stereocenters from enones and nitroalkanes.
Li
Pengfei
P
Dalian Institute of Chemical Physics, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Science, 457 Zhongshan Road, Dalian, 116023, China.
Wang
Yongcan
Y
Liang
Xinmiao
X
Ye
Jinxing
J
D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D009574:Nitro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000473:Alkanes; D002930:Cinchona Alkaloids; D007659:Ketones; D009574:Nitro Compounds