title: Lessons learned from the CRUSADE National Quality Improvement Initiative.
abstract: The CRUSADE National Quality Improvement Initiative was created to track national care patterns, facilitate process improvement, and improve patient outcomes among patients with acute coronary syndromes (ACS). CRUSADE found that patients in community practice were sicker than those in randomized clinical trials and often failed to receive evidence-based therapies. Dosing regimens of antithrombotic therapy were also suboptimal, raising safety concerns. Over time, guideline adherence and dosing regimens of ACS patients have improved dramatically, leading to significantly improved outcomes. Ongoing quality improvement efforts will be needed to further improve evidence-based and personalized care of patients with ACS.
authors.affiliation: Duke Clinical Research Institute, 2400 Pratt Street, Room 7009, Durham, NC 27705, USA. peter016@mc.duke.edu
authors.forename: Eric D
authors.initials: ED
authors.lastname: Peterson
authors.forename: David Z
authors.initials: DZ
authors.lastname: Bynum
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Roe
mesh_terms: D054058:Acute Coronary Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D015397:Program Evaluation; D011785:Quality Assurance, Health Care; D011787:Quality of Health Care / Q000592:standards*; D016896:Treatment Outcome; D014481:United States
chemical_list: D005343:Fibrinolytic Agents