Endothelial nuclear bulging: Morphological evidence for an intraglomerular perfusion regulating mechanism in the axolotl.
Kidneys of the Axolotl (Ambystoma mexicanum: Urodela, Amphibia) have been investigated by light and electron microscopy as well as microvascular corrosion casting. Numerous glomerular endothelial nuclei bulge into the glomerular capillary lumen. It is concluded that these cells virtually stop the blood-flow in the respective vessel by blockage of erythrocyte passage. A proposal for an intraglomerular regulation mechanism of capillary perfusion (and thus filtration) by endothelial isometric contraction in the Axolotl is made on the basis of morphological methods.
Ditrich
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Dept. Anatomy and Morphology, Institute for Zoology, University of Vienna, Althanstr. 14, Vienna, A-1090, Austria.
Splechtna
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