Use of the abiotic proton balance for determining linear relations among net conversion rates of primary metabolites in fermentation processes.
Linear relations among net conversion rates of primary metabolites in fermentation processes can be determined by using the macroscopic or pathway balancing methods. It is shown that the process observability can be improved by incorporating both the abiotic proton balance and the pH control reagent addition rate measurement into the balancing methods. (c) 1996 John Wiley & Sons, Inc.
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