Maternal virilization due to luteoma associated with delayed lactation.
OBJECTIVE
To report on a patient with virilization during pregnancy who experienced delayed lactation secondary to elevated maternal androgens.


METHODS
Case report and review of the literature.


METHODS
University hospital.


METHODS
A 32-year-old pregnant woman presented with virilization at 32 weeks' gestation.


METHODS
Laboratory evaluation, ultrasound examination, magnetic resonance imaging, cesarean section for fetal indication, nipple stimulation to facilitate lactation.


METHODS
Case report.


RESULTS
Postpartum normalization of serum T levels and patient ability to breastfeed exclusively after delayed initiation of lactation.


CONCLUSIONS
Maternal virilization during pregnancy is rare and is often due to androgen-secreting tumors that are benign. Therefore, careful evaluation of these patients is important to avoid inadvertent oophorectomy.
Dahl
Stephanie K
SK
Department of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA. skdahl@medicine.nodak.edu
Thomas
Michael A
MA
Williams
Daniel B
DB
Robins
Jared C
JC
D000328:Adult; D000728:Androgens / Q000097:blood; D001942:Breast Feeding; D002585:Cesarean Section; D005260:Female; D005865:Gestational Age; D006801:Humans; D007774:Lactation; D050498:Live Birth; D018311:Luteoma / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D015854:Up-Regulation; D014770:Virilism / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology
D000728:Androgens