Platelet-rich plasma for pediatric tonsillectomy patients.
OBJECTIVE
To determine if placement of autologous platelet-rich plasma (PRP) on the tonsil beds at the time of tonsillectomy would decrease postoperative pain and complications.


METHODS
Double blind, randomized, prospective study.


METHODS
Seventy children were recruited to participate in the study, ranging in age from 4 to 15 years. They were randomized to treatment (PRP) or control groups. The parents, patients, and nurses were blinded as to which group they were in. Postoperative pain scores were obtained using the FACES pain scale and recorded in a home diary.


RESULTS
Seventy patients were recruited to the study, and 12 did not submit their diaries and were considered to drop out of the study. Demographic data were similar for both control and treatment groups. Median pain scores, medication use, days to normal diet, and office visits did not differ between the two groups.


CONCLUSIONS
PRP applied once at the time of tonsillectomy does not improve postoperative pain or recovery in pediatric patients.
Sidman
James D
JD
Department of Otolaryngology, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota 55404, USA. sidma001@umn.edu
Lander
Timothy A
TA
Finkelstein
Marsha
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010149:Postoperative Pain / Q000517:prevention & control*; D053657:Platelet-Rich Plasma; D014068:Tonsillectomy