title: [The studies on the Ku Huang granula technology].
abstract: OBJECTIVE
  To determine the optimum technology of the Ku Huang granula.
  
  
  METHODS
  Making Emodin and Chrysophanol for index, using HPLC, extracturm softening point data and orthogonal design experiment to research the preparatory technology of the Ku Huang granula to screen the optimum technology.
  
  
  RESULTS
  The Ku Huang granula was pelletized at 100% dextrin, 170 degrees C- 175 degrees C spray drying and at the conditions of 75% ethylalcohol, 85 degrees C, 4 Hz, 3 hours fluidizing pelletization.
  
  
  CONCLUSIONS
  The optimum condition is reasonable.
authors.affiliation: Lei Yunshang Pharmaceutical Limited Company, Suzhou 215009, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Qian
authors.forename: Qi
authors.initials: Q
authors.lastname: Kuang
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
authors.forename: Jun
authors.initials: J
authors.lastname: Shen
mesh_terms: D000880:Anthraquinones / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification* / Q000592:standards; D004642:Emodin / Q000032:analysis; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry; D019664:Polygonaceae / Q000737:chemistry; D011786:Quality Control; D029909:Sophora / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013995:Time
chemical_list: D000880:Anthraquinones; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C530853:ku huang; D004642:Emodin; C027113:chrysophanic acid