Effect of intranasal oxygen administration on blood gas variables and outcome in neonatal calves with respiratory distress syndrome: 20 cases (2004-2006).
OBJECTIVE
To determine the effect of intranasal oxygen administration on blood gas variables and outcome in neonatal calves with respiratory distress syndrome (RDS).


METHODS
Retrospective case series.


METHODS
20 neonatal calves with RDS.


METHODS
Arterial partial pressure of oxygen (PaO(2)), arterial partial pressure of carbon dioxide, and arterial oxygen saturation (SaO(2)) before and after intranasal administration of oxygen were analyzed.


RESULTS
There were significant increases in PaO(2) and SaO(2) in the first 24 hours after oxygen administration was begun, with mean +/- SD PaO(2) increasing from 38.4+/-8.8 mm Hg to 58.7+/-17.8 mm Hg during the first 3 hours of treatment. Calves with PaO(2)>55 mm Hg within the first 12 hours after oxygen administration was begun had a significantly higher survival rate (9/10) than did calves that did not reach this threshold (4/10).


CONCLUSIONS
Results suggested that intranasal oxygen administration was a simple method of improving blood gas variables in neonatal calves with RDS and that PaO(2) could be used to predict outcome.
Bleul
Ulrich T
UT
Clinic of Reproductive Medicine, Department of Farm Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.
Bircher
Barbara M
BM
Kähn
Wolfgang K
WK
D000281:Administration, Intranasal; D000818:Animals; D000831:Animals, Newborn; D001784:Blood Gas Analysis / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000401:mortality / Q000628:therapy*; D005260:Female; D008297:Male; D010100:Oxygen / Q000627:therapeutic use*; D010313:Partial Pressure; D012131:Respiratory Insufficiency / Q000401:mortality / Q000628:therapy / Q000662:veterinary*; D012189:Retrospective Studies; D016019:Survival Analysis; D013577:Syndrome; D016896:Treatment Outcome
D010100:Oxygen