[Biocompatibility of dialysis fluid in peritoneal dialysis--limitations and possibilities of improvement].
Standard glucose dialysis solutions are characterised by low biocompatibility because of hyperosmolality, low pH, lactate buffer and presence of glucose degradation products. These factors cause failure of peritoneum as dialysis membrane. In our paper we present problems of biocompatibility of glucose-based solutions as well as possibilities of improvement in this field thanks to application of alternative solutions.
Olszowska
Anna
A
Wojskowy Instytut Medyczny w Warszawie, CSK MON, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii, Poland.
Wańkowicz
Zofia
Z
D001639:Bicarbonates / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry*; D015314:Dialysis Solutions / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000737:chemistry; D010530:Peritoneal Dialysis
D001639:Bicarbonates; D001672:Biocompatible Materials; D015314:Dialysis Solutions; D019344:Lactic Acid; D005947:Glucose