title: MicroCore: mapping genome expression to cell pathways and networks.
abstract: The MicroCore toolkit is a suite of analysis programs for microarray and proteomics data that is open source and programmed exclusively in Java. MicroCore provides a flexible and extensible environment for the interpretation of functional genomics data through visualization. The first version of the application (downloadable from the MicroCore website: http://www.ucl.ac.uk/oncology/MicroCore/microcore.htm), implements two programs-PIMs (protein interaction maps) and MicroExpress-and is soon to be followed by an extended version which will also feature a fuzzy k-means clustering application and a Java-based R plug-in for microarray analysis. PIMs and MicroExpress provide a simple yet powerful way of graphically relating large quantities of expression data from multiple experiments to cellular pathways and biological processes in a statistically meaningful way.
authors.affiliation: Department of Clinical Oncology, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK.
authors.forename: Manish
authors.initials: M
authors.lastname: Patel
authors.forename: Sylvia
authors.initials: S
authors.lastname: Nagl