title: [Thrombus in transit - two cases of patients with massive pulmonary embolism treated with thrombolysis].
abstract: Two cases of large, free-floating right heart thrombi in patients with massive pulmonary embolism and a history of deep vein thrombosis are presented. In a 30-year-old male with prominent obesity and a history of hypertension, disappearance of the thrombus at the end of alteplase infusion coexisted with onset of haemodynamic stabilization. In a 70-year-old female, the thrombus, which persisted despite streptokinase administration, translocated suddenly (during echocardiography) to the pulmonary artery, which resulted in a deterioration in her status. After alteplase administration following heparin infusion, steady clinical and echocardiographic improvement was observed.
authors.affiliation: Oddział Chorób Wewnetrznych Szpitala Miejskiego ZOZ Poznań - Nowe Miasto. welikowski@wp.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Elikowski
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Małek
authors.forename: Joanna
authors.initials: J
authors.lastname: Bestrzyńska
authors.forename: Rafał
authors.initials: R
authors.lastname: Kolasiński
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Sciskała
authors.forename: Wojciech
authors.initials: W
authors.lastname: Sarnowski
mesh_terms: D000368:Aged; D004452:Echocardiography; D005260:Female; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D013923:Thromboembolism / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator