title: Effect of hydration and continuous urinary drainage on urine production in children.
abstract: OBJECTIVE
  Although urine production depends on numerous physiological variables there are no quantitative data regarding the effect of bladder decompression, by means of continuous catheter drainage, on urine production. The aim of this study was to investigate this effect.
  
  
  METHODS
  The study was carried out in two stages, each consisting of two phases. The effect of two distinct orally administered amounts of water was recorded in relation to continuous bladder decompression on the changes with time of urine volume and the urine production rate. In the first stage, 35 children were randomly divided into two groups and two different hydration schemes (290 and 580 ml of water/m2) were used. After the second urination of Phase 1, continuous drainage was employed in the phase that followed (Phase 2). In the second stage, a group of 10 children participated and Phase 2 was carried out 1 day after the completion of Phase 1.
  
  
  RESULTS
  It was shown that the amount of urine produced increased in accordance with the degree of hydration and doubled or tripled with continual urine drainage by catheter for the same degree of hydration and within the same time interval. This was also true for Stage 2, in which Phase 2 was performed 24 h after Phase 1, indicating that diuresis during Phase 2 (as a result of Phase 1) was negligible.
  
  
  CONCLUSIONS
  It was shown that during continuous drainage of urine with bladder catheterization there is an increased need for fluids, which should be administered early.
authors.affiliation: Second Department of Pediatrics, A. P. Kyriakou Children's Hospital, Athens, Greece.
authors.forename: Marianthi
authors.initials: M
authors.lastname: Galetseli
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Dimitriou
authors.forename: Helen
authors.initials: H
authors.lastname: Tsapra
authors.forename: Maria
authors.initials: M
authors.lastname: Moustaki
authors.forename: Polyxeni
authors.initials: P
authors.lastname: Nicolaidou
authors.forename: Andrew
authors.initials: A
authors.lastname: Fretzayas
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D008297:Male; D014546:Urinary Catheterization; D014563:Urodynamics / Q000502:physiology*; D014882:Water-Electrolyte Balance / Q000502:physiology