title: Focal extramedullary haematopoiesis of the spleen: unusual MR appearance with pathological correlation.
abstract: We report the unusual MR appearance of focal extramedullary haematopoiesis (EMH) of the spleen in a 72-year-old man with thrombocytopenia. Variable MR signal characteristics of EMH, which depend upon the amount of fat and the level of haematopoietic activity, have been described previously. We believe, however, that the delayed central enhancement of EMH on MRI findings was exceptional and has not been reported previously. After pathological investigation and correlation, we believe that the central zone containing hypocellular collagenous bundles may account for this specific enhancement.
authors.affiliation: Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, 325, Cheng-Kung Road, Sec 2, Taipei 114, Taiwan, Republic of China.
authors.forename: C-W
authors.initials: CW
authors.lastname: Wang
authors.forename: C-Y
authors.initials: CY
authors.lastname: Yu
authors.forename: Y-J
authors.initials: YJ
authors.lastname: Peng
authors.forename: C-Y
authors.initials: CY
authors.lastname: Wang
authors.forename: W-C
authors.initials: WC
authors.lastname: Chang
authors.forename: G-S
authors.initials: GS
authors.lastname: Huang
mesh_terms: D000368:Aged; D005682:Gadolinium; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011868:Radioisotopes; D013156:Splenectomy; D013158:Splenic Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D013921:Thrombocytopenia / Q000097:blood / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D011868:Radioisotopes; D005682:Gadolinium