title: Primary angiosarcoma of the brain in a child.
abstract: We describe a pediatric case of primary angiosarcoma of the brain displaying striking intravascular papillary pattern, consistent with the "Dabska tumor," often in continuity with a massive, multifocal intravascular papillary endothelial hyperplasia. The tumor contained small hemangioma and obliterated dysplastic arteries as well as very large thin-walled veins. The surrounding brain tissue showed scattered telangiectasias, conglomerates of calcified dysplastic arteries, old hemorrhages and gliosis. Colocalization of these lesions suggests the development of a papillary angiosarcoma in the pre-existing vascular malformation. Although never reported, the possibility of a malignant transformation of endothelial papillary hyperplasia also should be considered in this case.
authors.affiliation: Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. boleklach2@hotmail.com
authors.forename: Boleslaw
authors.initials: B
authors.lastname: Lach
authors.forename: Maher
authors.initials: M
authors.lastname: Hassounah
authors.forename: Yasser
authors.initials: Y
authors.lastname: Khafaga
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002648:Child; D003399:Craniotomy; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D009362:Neoplasm Metastasis; D009383:Neoplasms, Vascular Tissue / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011859:Radiography