title: Eosinophilic angiocentric fibrosis of the sinonasal tract.
abstract: Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory fibrosing lesion of the upper respiratory tract and orbit that occurs mainly in young to middle-aged women. The etiology of EAF is unknown. To our knowledge, approximately 28 cases have been previously reported in the English literature. We report here 3 additional cases of EAF of the sinonasal tract; 2 in women aged 19 and 31 years, and 1 in a man aged 49 years. The 19-year-old woman is the youngest patient with EAF ever described. The patients presented with a nasal cavity mass, face pain, or nasal obstructive symptoms of long duration.
authors.affiliation: Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA.
authors.forename: Ognjen
authors.initials: O
authors.lastname: Kosarac
authors.affiliation: Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: Mario A
authors.initials: MA
authors.lastname: Luna
authors.affiliation: Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA.
authors.forename: Jae Y
authors.initials: JY
authors.lastname: Ro
authors.affiliation: Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA. Electronic address: aayala@tmh.tmc.edu.
authors.forename: Alberto G
authors.initials: AG
authors.lastname: Ayala
mesh_terms: D000328:Adult; D004802:Eosinophilia / Q000473:pathology*; D005157:Facial Pain / Q000473:pathology; D005260:Female; D005355:Fibrosis; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology; D015508:Nasal Obstruction / Q000209:etiology* / Q000473:pathology*; D009300:Nasal Septum / Q000473:pathology