title: Prenatal ultrasonographic diagnosis of persistent hyperplastic primary vitreous.
abstract: Persistent hyperplastic primary vitreous (PHPV) is a rare developmental malformation of the eye characterized by the presence of a vascular membrane located behind the lens. We report, for the first time in the literature, the identification on ultrasound examination of bilateral cataract and thickened hyaloid artery-lens junction, leading to a diagnosis of bilateral PHPV, in a fetus at 23 weeks' gestation. Histological examination at postmortem confirmed the prenatal diagnosis of bilateral PHPV and cataract. A thorough ultrasound examination of the fetal eye in cases with cataract is recommended.
authors.affiliation: Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel. eldad210@bezeqint.net
authors.forename: E
authors.initials: E
authors.lastname: Katorza
authors.forename: M
authors.initials: M
authors.lastname: Rosner
authors.forename: Y
authors.initials: Y
authors.lastname: Zalel
authors.forename: Y
authors.initials: Y
authors.lastname: Gilboa
authors.forename: R
authors.initials: R
authors.lastname: Achiron
mesh_terms: D000028:Abortion, Induced; D002386:Cataract / Q000000981:diagnostic imaging* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005865:Gestational Age; D006801:Humans; D007908:Lens, Crystalline / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D054514:Persistent Hyperplastic Primary Vitreous / Q000000981:diagnostic imaging* / Q000473:pathology; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D014822:Vitreous Body / Q000002:abnormalities / Q000000981:diagnostic imaging*