A new 5,11-epoxymegastigmane glucoside from Acanthus ilicifolius.
From a China mangrove plant Acanthus ilicifolius Linn., a new compound, 5,11-epoxymegastigmane glucoside (1) was isolated along with one known compound of megastigmane glucosides, (6S, 9S)-roseoside (2). The structure of compound 1 was determined on the basis of 1D- and 2D-NMR techniques (DEPT, COSY, HMBC, HMQC, NOESY) and HR-FABMS. The structure of 1 was established as (1S, 3S, 5R, 6R, 7E)-5,11-epoxy-3-hydroxymegastigman-7-en-9-one-3-O-beta-D-glucopyranoside.
Huo
Changhong
C
Department of Natural Medicines and the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, P. R. China.
Liang
Hong
H
Tu
Guangzhong
G
Zhao
Yuying
Y
Lin
Wenhan
W
D027901:Acanthaceae / Q000737:chemistry*; D003512:Cyclohexanones / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D045792:Norisoprenoids / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment
C534119:5,11-epoxymegastigmane glucoside; D003512:Cyclohexanones; D005960:Glucosides; D045792:Norisoprenoids; C413264:megastigmane