[Chronic virus infections in combination with tubercular process].
The objective of this study was to investigate the role of chronic viral infections in development of the atypical and complicated forms of tuberculosis. Were investigated human herpes virus-2 (HHV-2), cytomegalovirus (CMV) and hepatitis C virus (HCV). Chronic viral infections have been identified as a risk factor for developing and complicated tuberculosis. Research has been shown, that infection of chronic virus diseases in patients with tuberculosis is rather significant and in several times exceeds similar parameters in healthy persons (CMV: 5.8% in healthy persons and 68.5% in patients with tuberculosis; HHV-2: 39% in healthy persons, 92%in patients with tuberculosis; HCV: in 36.4% patients with tuberculosis complicated with cirrhosis). The high level of chronic virus diseases and/or high frequency of their activization at patients with tuberculosis of various forms testify to interrelation between them. Increased level of chronic viral infections in patients with tuberculosis explained by the social factors and tuberculosis-induced immunodeficiency.
Karalian
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MA
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D005846:Georgia (Republic) / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014376:Tuberculosis / Q000150:complications*; D014777:Virus Diseases / Q000150:complications* / Q000453:epidemiology