[Functions of protein MTS1 (S100A4) in normal and tumor cells].
To date vast evidence has been accumulated showing the role of protein MTS1 in the metastasis development and cell motility regulation, both in norm and upon pathological change of various tissues. The structure of the protein and its gene, as well as the regulation of the gene expression, are studied in detail. Significant advances have been achieved in understanding molecular mechanisms involving MTS1. This paper reviews the current knowledge of the issue.
Koshelev
Iu A
IuA
Georgiev
G P
GP
Kibardin
A V
AV
D000818:Animals; D002465:Cell Movement / Q000235:genetics; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000235:genetics* / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics*; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism*; D009928:Organ Specificity / Q000235:genetics
D019941:Cyclin-Dependent Kinase Inhibitor p16