Importance of type II secretion for survival of Legionella pneumophila in tap water and in amoebae at low temperatures.
Legionella pneumophila type II secretion mutants showed reduced survival in both tap water at 4 to 17 degrees C and aquatic amoebae at 22 to 25 degrees C. Wild-type supernatants stimulated the growth of these mutants, indicating that secreted factors promote low-temperature survival. There was a correlation between low-temperature survival and secretion function when 12 additional Legionella species were examined.
Söderberg
Maria A
MA
Department of Microbiology and Immunology, Northwestern University Medical School, Chicago, IL 60611, USA.
Dao
Jenny
J
Starkenburg
Shawn R
SR
Cianciotto
Nicholas P
NP
D048248:Acanthamoeba castellanii / Q000382:microbiology*; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D003080:Cold Temperature; D006249:Hartmannella / Q000382:microbiology*; D016952:Legionella pneumophila / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D050296:Microbial Viability; D009154:Mutation; D014871:Water Microbiology
D001426:Bacterial Proteins