title: Polypoidal choroidal vasculopathy with drusen.
abstract: OBJECTIVE
  To study the prevalence and clinical features of drusen in eyes with polypoidal choroidal vasculopathy (PCV).
  
  
  METHODS
  Retrospectively, we reviewed the records of 98 consecutive patients with PCV (102 eyes). Drusen were examined in the inner macula, which was defined as an area within 1500 microm of the center of the fovea. Eyes that had at least one intermediate or large (>or=63 microm) soft drusen within the inner macula were defined as having drusen.
  
  
  RESULTS
  In these 102 eyes with PCV, 23 (23%) showed soft drusen in the inner macula. In such cases, the fellow eyes, those without a PCV lesion, sometimes also showed soft drusen in the inner macula (11 eyes); 34 (33%) of the eyes with PCV had soft drusen in the inner macula of at least one eye. Comparison of the group of eyes with PCV and drusen in one or both eyes with the group with PCV and no drusen in either eye revealed no significant difference in patient characteristics or in ocular manifestations.
  
  
  CONCLUSIONS
  Drusen are not an unusual feature of PCV, at least in Japanese patients, and, when present, they appear to have only a minor effect, if any, on the clinical course.
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Iwama
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan. tujikawa@kuhp.kyoto-u.ac.jp.
authors.forename: Akitaka
authors.initials: A
authors.lastname: Tsujikawa
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Sasahara
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Hirami
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tamura
authors.affiliation: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Nagahisa
authors.initials: N
authors.lastname: Yoshimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000150:complications* / Q000175:diagnosis; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000150:complications* / Q000175:diagnosis; D015995:Prevalence; D015593:Retinal Drusen / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green