title: Advancement of flow-based analysis with alternative chemical reactions and new devices for environmental and biological samples.
abstract: This review includes our researches and other methodologies related to flow-based techniques, such as flow injection analysis (FIA) and sequential injection analysis (SIA). The methods will demonstrate semi-and full automated FIA and SIA, including liquid-liquid and liquid-solid extraction. FIA using alternative chemical reactions in the aqueous solution was applied to the trace analysis of metals in biological and environmental samples. For durable liquid-liquid extraction, several phase separators were designed. Moreover, multi-channel FIA with newly designed flow cells and SIA with lab-on-valve devices have been used for the simultaneous and successive determination of metals and organic compounds. On-line solid phase extraction (SPE) has also been proposed for highly sensitive analysis of organic and inorganic compounds.
authors.affiliation: Department of Applied Chemistry, Aichi Institute of Technology, Yakusa, Toyota, Japan. tadsakai@aitech.ac.jp
authors.forename: Tadao
authors.initials: T
authors.lastname: Sakai
authors.forename: Norio
authors.initials: N
authors.lastname: Teshima
mesh_terms: D001331:Automation; D001695:Biology; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004777:Environment; D017022:Flow Injection Analysis / Q000295:instrumentation / Q000379:methods*; D007287:Inorganic Chemicals / Q000032:analysis*; D008670:Metals / Q000032:analysis*; D009930:Organic Chemicals / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D052617:Solid Phase Microextraction
chemical_list: D007287:Inorganic Chemicals; D008670:Metals; D009930:Organic Chemicals