title: Assessment of current practice in the diagnosis and therapy of idiopathic pulmonary fibrosis.
abstract: BACKGROUND
  The consensus statement on the Diagnosis and Therapy of Idiopathic Pulmonary Fibrosis (IPF) formulated by the American Thoracic Society/European Respiratory Society (ATS/ERS) was published in 2000. Acceptance and implementation of these guidelines have not been assessed. We surveyed the fellows of the American College of Chest Physicians (FCCP) to establish current practice patterns regarding the diagnosis and therapy of IPF.
  
  
  METHODS
  We electronically distributed a 32-item questionnaire to all 6443 pulmonary medicine board-certified Fellows of the American College of Chest Physicians. The response rate was 13%. Demographic characteristics were similar between respondents and non-respondents.
  
  
  RESULTS
  Seventy-two percent of respondents were familiar with the ATS/ERS consensus statement and 63% found it clinically useful. However, a similar number of respondents indicated that an update is needed. Bronchoscopy and surgical lung biopsy are used infrequently. Forty-five percent of pulmonary physicians advocate providing only supportive care for patients outside of clinical trials. If pharmacological therapy is recommended, prednisone (either alone or in combination with azathioprine) or off-label agents are preferentially prescribed. Despite physician awareness (79%) of clinical trials, interested patients are not consistently referred (54%). A majority of respondents (61%) felt that lung transplantation represents the only effective therapy for IPF, and 86% refer their patients to lung transplant centers.
  
  
  CONCLUSIONS
  There is substantial variability among pulmonary physicians in the diagnosis and management of IPF. This may, in part, reflect the current lack of effective pharmacologic therapy. Updated practice guidelines are needed for the diagnosis and therapy of IPF.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Mayo Building East 18, Rochester, MN, USA. peikert.tobias@mayo.edu
authors.forename: T
authors.initials: T
authors.lastname: Peikert
authors.forename: C E
authors.initials: CE
authors.lastname: Daniels
authors.forename: T J
authors.initials: TJ
authors.lastname: Beebe
authors.forename: K C
authors.initials: KC
authors.lastname: Meyer
authors.forename: J H
authors.initials: JH
authors.lastname: Ryu
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D001706:Biopsy / Q000706:statistics & numerical data; D001999:Bronchoscopy / Q000706:statistics & numerical data; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D019983:Guideline Adherence; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000175:diagnosis* / Q000188:drug therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011241:Prednisone / Q000627:therapeutic use; D015272:Pulmonary Medicine; D014481:United States
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D001379:Azathioprine; D011241:Prednisone