[Cryoglobulinemia].
Cryoglobulins are immunoglobulins that precipitate at temperatures below 37 degrees C. They mainly occur in association with hepatitis C but also in other persistent viral infections and autoimmune as well as hematologic diseases. As circulating immune-complexes, they can cause severe tissue damage in virtually all organs, in particular the skin, joints and kidneys. This article gives a review on the different types of cryoglobulinemia, their clinical presentation and current therapeutic strategies.
Ottl
Tobias
T
Abteilung Transplantationsimmunologie und Nephrologie, Medizinische Klinik, Universitätsspital Basel, Petersgraben 4, Basel. oettlt@uhbs.ch
Trendelenburg
Marten
M
D003449:Cryoglobulinemia / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D003450:Cryoglobulins / Q000276:immunology*; D006801:Humans
D003450:Cryoglobulins