New insights into adolescent acne.
OBJECTIVE
Acne vulgaris remains one of the most common conditions affecting adolescents. The pediatric practitioner is the first to evaluate adolescent acne, making familiarity with the condition and its management essential. This review covers some of the recent literature regarding acne to help practitioners stay current on the issues regarding this topic.


RESULTS
The pathogenesis of acne is multifactorial and complex, but recent advances in molecular genetics have provided additional information on the actions of Proprionibacterium acnes. Nutritional studies have reevaluated a possible role for diet and lifestyle factors in acne development. Many therapies are available to control acne and to limit associated scarring. Their appropriate use requires an understanding of not only the benefits but also the possible risks and adverse effects involved. Recent concerns regarding the use of antibiotics and isotretinoin will be addressed.


CONCLUSIONS
This study reviews the recent literature regarding teenage acne, focusing on pathogenesis, associations, and controversies and considerations in therapy.
Tom
Wynnis L
WL
Department of Pediatrics and Medicine (Dermatology), University of California, San Diego, California, USA.
Barrio
Victoria R
VR
D000152:Acne Vulgaris / Q000209:etiology / Q000378:metabolism* / Q000628:therapy*; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003611:Dairy Products / Q000009:adverse effects; D003879:Dermatologic Agents / Q000627:therapeutic use; D015444:Exercise / Q000502:physiology; D038321:Glycemic Index; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use; D008967:Molecular Biology; D017592:Skin Care; D013315:Stress, Psychological / Q000503:physiopathology; D013546:Sweating
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D015474:Isotretinoin