[The studies on the Ku Huang granula technology].
OBJECTIVE
To determine the optimum technology of the Ku Huang granula.


METHODS
Making Emodin and Chrysophanol for index, using HPLC, extracturm softening point data and orthogonal design experiment to research the preparatory technology of the Ku Huang granula to screen the optimum technology.


RESULTS
The Ku Huang granula was pelletized at 100% dextrin, 170 degrees C- 175 degrees C spray drying and at the conditions of 75% ethylalcohol, 85 degrees C, 4 Hz, 3 hours fluidizing pelletization.


CONCLUSIONS
The optimum condition is reasonable.
Qian
Kun
K
Lei Yunshang Pharmaceutical Limited Company, Suzhou 215009, China.
Kuang
Qi
Q
Dong
Wei
W
Shen
Jun
J
D000880:Anthraquinones / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification* / Q000592:standards; D004642:Emodin / Q000032:analysis; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry; D019664:Polygonaceae / Q000737:chemistry; D011786:Quality Control; D029909:Sophora / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013995:Time
D000880:Anthraquinones; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C530853:ku huang; D004642:Emodin; C027113:chrysophanic acid