title: Colchicine intoxication and infection risk: a case report.
abstract: Colchicine is widely used, primarily for the treatment of gouty arthritis and familial Mediterranean fever. Colchicine intoxication is a rare but potentially life-threatening event. Herein, we reported a 26-year-old woman who presented to the emergency department after ingesting 27.5 mg of colchicine in a suicide attempt. She exhibited signs typical of colchicine-poisoning and developed infectious complications but with subsequent complete recovery. This paper discusses the role of colchicine poisoning in increasing susceptibility to infections. This aspect is usually under-appreciated in the clinical picture of colchicine overdose.
authors.affiliation: Infectious Diseases & Clinical Microbiology Department, Ankara Research & Training Hospital, Ankara, Turkey. drzeliha@hotmail.com
authors.forename: Z
authors.initials: Z
authors.lastname: Kocak
authors.forename: H
authors.initials: H
authors.lastname: Akay
authors.forename: S
authors.initials: S
authors.lastname: Gucenmez
authors.forename: A
authors.initials: A
authors.lastname: Tufan
authors.forename: O
authors.initials: O
authors.lastname: Donderici
mesh_terms: D000328:Adult; D003078:Colchicine / Q000506:poisoning*; D062787:Drug Overdose; D004638:Emergency Treatment; D005260:Female; D006074:Gout Suppressants / Q000506:poisoning*; D006801:Humans; D007239:Infections / Q000209:etiology*; D013406:Suicide, Attempted
chemical_list: D006074:Gout Suppressants; D003078:Colchicine