Imaging of pediatric lymphomas.
Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) represent 10% to 15% of all malignancies occurring in children younger than 20 years of age. Advances in cross-sectional imaging and the availability of positron emission tomography (PET) and PET-CT have had a major impact on imaging and management of pediatric patients. This article reviews the clinical features of lymphoma, focusing on the spectrum of imaging findings seen in diagnosis, staging, and follow-up of HL and NHL. Pediatric NHL has four major histologic subtypes: Burkitt lymphoma, diffuse large B-cell lymphoma, anaplastic large cell lymphoma, and lymphoblastic lymphoma. The most important subtype of HL is nodular sclerosis.
Abramson
Sara J
SJ
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. abramsos@mskcc.org
Price
Anita P
AP
D002648:Child; D003952:Diagnostic Imaging; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology; D009367:Neoplasm Staging