title: [Usage of beta-adrenolytic agents in patients with chronic pulmonary obstructive disease].
abstract: Beta-blockers are commonly used in the contemporary pharmacotherapy. They are considered the drugs of choice in the treatment of many, especially cardiological, disorders. Chronic obstructive pulmonary disease (COPD) is a very common disease, which is classified as the fourth cause of the chronic morbidity and mortality in the USA. Frequent occurrence, as well as the fact that some risk factors, such as cigarette smoking, are common for both COPD and cardiovascular diseases cause that the number of patients suffering from their coexistence is increasing. Because first beta-blockers had a strong bronchoconstrictory effect, their use is contraindicated in conditions associated with airway obstruction. This review was aimed to investigate the safety of using of beta-blockers in patients with COPD. We try to answer whether selective beta-blockers and so-called hybrid beta-blockers are safe for patients suffering from this disorder. We also try to elaborate some therapeutic recommendations.
authors.affiliation: Slaski Uniwersytet Medyczny, Klinika Chorób Wewnetrznych i Farmakologii Klinicznej. boolean@poczta.onet.pl
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Bułdak
authors.forename: Anna
authors.initials: A
authors.lastname: Duława
authors.forename: Robert
authors.initials: R
authors.lastname: Krysiak
authors.forename: Bogusław
authors.initials: B
authors.lastname: Okopień
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D000319:Adrenergic beta-Antagonists