title: [Effect of yupingfengsan on the growth of tumor and immunological function in tumor-bearing mice].
abstract: OBJECTIVE
  To explore the effect of yupingfengsan on the growth of tumor and immunological function in tumor-bearing mice.
  
  
  METHODS
  The models of tumor-bearing mice were established by inoculating the healthy mice with S180 tumor carneus cells cultured in vitro. Then the ratio of tumor restriction was calculated. The phagocytosis activity of phagocytes, the level of NO secreted by phagocytes, the proliferating activity of T lymphocytes and the level of IL-2 were detected in the mice after being treated with yupingfengsan 12 days.
  
  
  RESULTS
  yupingfengsan elevated the phagocytosis of phagocytes and the level of NO secreted by phagocytes. It promoted T lymphocytes to transform, and increased the level of IL-2 and the activity of NK cells.
  
  
  CONCLUSIONS
  yupingfengsan can increase the immunological function of tumor-bearing mice and suppress the development of tumor in mice.
authors.affiliation: Department of Pathogenic Biology, Mudanjiang Medical College, Mudanjiang 157011, China. zhanghj33@yahoo.com.cn
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Zhang
authors.forename: Xiao-Yun
authors.initials: XY
authors.lastname: Tang
authors.forename: Bao-Ling
authors.initials: BL
authors.lastname: Ju
authors.forename: Bao-Hui
authors.initials: BH
authors.lastname: Song
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D007376:Interleukin-2 / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009589:Nitrogen Oxides / Q000378:metabolism; D010586:Phagocytes / Q000187:drug effects / Q000378:metabolism; D010587:Phagocytosis / Q000187:drug effects; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D007376:Interleukin-2; D009589:Nitrogen Oxides