title: The auxin influx carrier LAX3 promotes lateral root emergence.
abstract: Lateral roots originate deep within the parental root from a small number of founder cells at the periphery of vascular tissues and must emerge through intervening layers of tissues. We describe how the hormone auxin, which originates from the developing lateral root, acts as a local inductive signal which re-programmes adjacent cells. Auxin induces the expression of a previously uncharacterized auxin influx carrier LAX3 in cortical and epidermal cells directly overlaying new primordia. Increased LAX3 activity reinforces the auxin-dependent induction of a selection of cell-wall-remodelling enzymes, which are likely to promote cell separation in advance of developing lateral root primordia.
authors.affiliation: School of Biosciences & Centre for Plant Integrative Biology, University of Nottingham, LE12 5RD, UK.
authors.forename: Kamal
authors.initials: K
authors.lastname: Swarup
authors.forename: Eva
authors.initials: E
authors.lastname: Benková
authors.forename: Ranjan
authors.initials: R
authors.lastname: Swarup
authors.forename: Ilda
authors.initials: I
authors.lastname: Casimiro
authors.forename: Benjamin
authors.initials: B
authors.lastname: Péret
authors.forename: Yaodong
authors.initials: Y
authors.lastname: Yang
authors.forename: Geraint
authors.initials: G
authors.lastname: Parry
authors.forename: Erik
authors.initials: E
authors.lastname: Nielsen
authors.forename: Ive
authors.initials: I
authors.lastname: De Smet
authors.forename: Steffen
authors.initials: S
authors.lastname: Vanneste
authors.forename: Mitch P
authors.initials: MP
authors.lastname: Levesque
authors.forename: David
authors.initials: D
authors.lastname: Carrier
authors.forename: Nicholas
authors.initials: N
authors.lastname: James
authors.forename: Vanessa
authors.initials: V
authors.lastname: Calvo
authors.forename: Karin
authors.initials: K
authors.lastname: Ljung
authors.forename: Eric
authors.initials: E
authors.lastname: Kramer
authors.forename: Rebecca
authors.initials: R
authors.lastname: Roberts
authors.forename: Neil
authors.initials: N
authors.lastname: Graham
authors.forename: Sylvestre
authors.initials: S
authors.lastname: Marillonnet
authors.forename: Kanu
authors.initials: K
authors.lastname: Patel
authors.forename: Jonathan D G
authors.initials: JD
authors.lastname: Jones
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Taylor
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Schachtman
authors.forename: Sean
authors.initials: S
authors.lastname: May
authors.forename: Goran
authors.initials: G
authors.lastname: Sandberg
authors.forename: Philip
authors.initials: P
authors.lastname: Benfey
authors.forename: Jiri
authors.initials: J
authors.lastname: Friml
authors.forename: Ian
authors.initials: I
authors.lastname: Kerr
authors.forename: Tom
authors.initials: T
authors.lastname: Beeckman
authors.forename: Laurent
authors.initials: L
authors.lastname: Laplaze
authors.forename: Malcolm J
authors.initials: MJ
authors.lastname: Bennett
mesh_terms: D017360:Arabidopsis; D029681:Arabidopsis Proteins / Q000502:physiology*; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000494:pharmacology*; D026901:Membrane Transport Proteins / Q000502:physiology*; D010937:Plant Growth Regulators / Q000494:pharmacology; D018517:Plant Roots / Q000166:cytology / Q000254:growth & development*
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D007210:Indoleacetic Acids; C531125:LAX3 protein, Arabidopsis; D026901:Membrane Transport Proteins; D010937:Plant Growth Regulators