A case of invasive rhinosinusitis by Fusarium verticillioides (Saccardo) Nirenberg in an apparently immunocompetent patient.
A case of chronic invasive rhinosinusitis in an apparently healthy man, caused by Fusarium verticillioides, is described. The identity of the isolate as F. verticillioides was established by demonstrating characteristic morphological features and by amplification of rDNA using species-specific primers. Surgical debridement of the infected nasal tissue and therapy with amphotericin B resulted in a favorable outcome. To the best of our knowledge, F. verticillioides has not been described previously to cause this condition.
Macêdo
Danielle P C
DP
Departamento de Micologia, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brasil. danielle_xande@yahoo.com.br
Neves
Rejane P
RP
Fontan
Juliana
J
Souza-Motta
Cristina M
CM
Lima
Débora
D
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D004271:DNA, Fungal / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D005670:Fusarium / Q000166:cytology / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D012220:Rhinitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012852:Sinusitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D000666:Amphotericin B