title: Malignant prolactinoma with craniospinal metastasis in a 12-year-old boy.
abstract: The authors report the clinical features of and imaging studies on a rare case of pediatric malignant prolactinoma. A 12-year-old boy presented with ataxia, blurred vision, and consciousness disturbance. He had received transcranial surgery and adjuvant radiotherapy. However, the tumor regrew with craniospinal metastasis 16 months after the operation. The relevant literature was reviewed regarding the clinical presentation, pathogenesis, treatment approaches, and prognosis of malignant prolactinoma.
authors.affiliation: Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7 Chung San South Road, Taipei, Taiwan, ROC.
authors.forename: Abel Po-Hao
authors.initials: AP
authors.lastname: Huang
authors.forename: Shih-Hung
authors.initials: SH
authors.lastname: Yang
authors.forename: Chi-Cheng
authors.initials: CC
authors.lastname: Yang
authors.forename: Meng-Fai
authors.initials: MF
authors.lastname: Kuo
authors.forename: Mu Zon
authors.initials: MZ
authors.lastname: Wu
authors.forename: Yong-Kwang
authors.initials: YK
authors.lastname: Tu
mesh_terms: D016543:Central Nervous System Neoplasms / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D019635:Neurosurgical Procedures; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D015175:Prolactinoma / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D011878:Radiotherapy