title: Microwave activation of enzymatic catalysis.
abstract: Microwave irradiation can be used to regulate biocatalysis. Herein, the utilization of hyperthermophilic enzymes in a microwave reactor is reported. While these enzymes are inactive at low temperatures, they can be activated with microwave irradiation. To the best of our knowledge, this is the first illustration of a specific microwave effect in enzymatic catalysis.
authors.affiliation: Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Young
authors.forename: Jason
authors.initials: J
authors.lastname: Nichols
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kelly
authors.forename: Alexander
authors.initials: A
authors.lastname: Deiters
mesh_terms: D043182:Carboxylesterase / Q000378:metabolism; D002384:Catalysis; D004798:Enzymes / Q000378:metabolism*; D006358:Hot Temperature; D007700:Kinetics; D008872:Microwaves; D020027:Pyrococcus furiosus / Q000201:enzymology; D048229:Sulfolobus solfataricus / Q000201:enzymology; D020124:Thermotoga maritima / Q000201:enzymology; D000519:alpha-Galactosidase / Q000378:metabolism; D001617:beta-Glucosidase / Q000378:metabolism
chemical_list: D004798:Enzymes; D043182:Carboxylesterase; D001617:beta-Glucosidase; D000519:alpha-Galactosidase