title: Multicentric squamous cell carcinona in a paca (Agouti paca) resembling Bowen's disease.
abstract: An 8-yr-old female paca (Agouti paca) was admitted at the Veterinary Hospital of the Belo Horizonte Zoo (Brazil) with an ulcerated cutaneous nodule of approximately 1.5 cm in diameter in the left ear. One week later, other cutaneous nodules were detected in various body locations. The animal died during a surgical procedure to remove the tumors. All cutaneous nodules were histologically similar with features of squamous cell carcinoma. Considering the predominant in situ nature of the lesion as well as its multicentric localization, the disease reported here closely resembles Bowen's disease, which has been described in humans and which has been identified as a rare neoplastic disease of cats, with one single report in a dog. This is the first report of a neoplastic disease in Agouti
authors.affiliation: Fundação Zoo-botânica de Belo Horizonte, Av. Otacílio Negrão de Lima, 8000 31365-450 Belo Horizonte, MG, Brazil.
authors.forename: Marcela M
authors.initials: MM
authors.lastname: Luppi
authors.forename: Marcelo C C
authors.initials: MC
authors.lastname: Malta
authors.forename: Maria E L T
authors.initials: ME
authors.lastname: Costa
authors.forename: Rafael O C
authors.initials: RO
authors.lastname: Motta
authors.forename: Renato L
authors.initials: RL
authors.lastname: Santos
mesh_terms: D000818:Animals; D000835:Animals, Wild; D001913:Bowen's Disease / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D012376:Rodent Diseases / Q000175:diagnosis* / Q000473:pathology*; D012377:Rodentia; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*