Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions.
Hay
Sam
S
Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Pang
Jiayun
J
Monaghan
Phillip J
PJ
Wang
Xi
X
Evans
Rhiannon M
RM
Sutcliffe
Michael J
MJ
Allemann
Rudolf K
RK
Scrutton
Nigel S
NS
D000426:Alcohol Dehydrogenase / Q000737:chemistry*; D002384:Catalysis; D001411:Geobacillus stearothermophilus / Q000201:enzymology; D006859:Hydrogen / Q000737:chemistry*; D007554:Isotopes; D007700:Kinetics; D008956:Models, Chemical; D015335:Molecular Probes / Q000737:chemistry; D009243:NAD / Q000737:chemistry; D009249:NADP / Q000737:chemistry; D010084:Oxidation-Reduction; D010453:Peptide Synthases / Q000737:chemistry*; D011789:Quantum Theory; D020124:Thermotoga maritima / Q000201:enzymology
D007554:Isotopes; D015335:Molecular Probes; D009243:NAD; D009249:NADP; D006859:Hydrogen; D000426:Alcohol Dehydrogenase; D010453:Peptide Synthases; C020041:dihydrofolate synthetase