title: [Study on the release of oleanolic acid loaded nanocapsules in vitro].
abstract: OBJECTIVE
  To study the release of oleanolic acid loaded nanocapsules in vitro.
  
  
  METHODS
  The rules of drug release in vitro from oleanolic acid loaded nanocapsules were observed by dynamic penetration system and HPLC.
  
  
  RESULTS
  The profile curve of oleanolic acid loaded nanocapsules was fit for the Weibull equation. The release t(1/2) of oleanolic acid loaded nanocapsules was about 6.7 times as that of original oleanolic acid.
  
  
  CONCLUSIONS
  Oleanolic acid loaded nanocapsules have obviously sustained effect.
authors.affiliation: Xiangya Hospital, Central South University, Changsha 410008, China. huangyihy2008@163.com
authors.forename: Yi
authors.initials: Y
authors.lastname: Huang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Li
authors.forename: Xin-Zhong
authors.initials: XZ
authors.lastname: Li
authors.forename: Shao
authors.initials: S
authors.lastname: Liu
authors.forename: Peng
authors.initials: P
authors.lastname: Lei
authors.forename: Jin
authors.initials: J
authors.lastname: Xiao
mesh_terms: D002214:Capsules; D003487:Cyanoacrylates / Q000737:chemistry; D004337:Drug Carriers; D016503:Drug Delivery Systems; D053769:Nanocapsules / Q000737:chemistry*; D009828:Oleanolic Acid / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics*; D010316:Particle Size; D011091:Polyesters / Q000737:chemistry; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D002214:Capsules; D003487:Cyanoacrylates; D004337:Drug Carriers; D053769:Nanocapsules; D011091:Polyesters; D009828:Oleanolic Acid