Minocycline: old and new therapeutic uses.
Since the introduction of minocycline HCl in the late 1960's, it has been used for disease states that have ranged from typical community-acquired infectious diseases to others that are non-infectious, such as resistant rheumatoid arthritis. Owing to its high penetration characteristics throughout the body, minocycline can be used in the treatment of a wide variety of extracellular and intracellular pathogens. This review examines the known and potential therapeutic uses of minocycline in a clinical setting.
Freeman
C D
CD
Department of Pharmacy Practice, College of Pharmacy, Butler University, Indianapolis, IN 46208, USA; Department of Pharmacy, Community Hospital East, Indianapolis, IN, USA.
Nightingale
C H
CH
Quintiliani
R
R