title: Successful treatment for chromoblastomycosis caused by Fonsecaea monophora: a report of three cases in Guangdong, China.
abstract: Fonsecaea pedrosoi is the most prevalent aetiological agent of chromoblastomycosis. Fonsecaea monophora is a new species segregated from Fonsecaea pedrosoi. Herein, we report on three cases of chromoblastomycosis caused by F. monophora that were successfully treated with terbinafine and/or itraconazole. Clinical characteristics and mycological parameters are described. Two of the three patients underwent combination therapy with itraconazole and terbinafine during early stages of treatment and were completely healed in a relatively short course of treatment.
authors.affiliation: Department of Dermatology, Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Junmin
authors.initials: J
authors.lastname: Zhang
authors.forename: Liyan
authors.initials: L
authors.lastname: Xi
authors.forename: Changming
authors.initials: C
authors.lastname: Lu
authors.forename: Xiqing
authors.initials: X
authors.lastname: Li
authors.forename: Ting
authors.initials: T
authors.lastname: Xie
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Xie
authors.forename: Sybren
authors.initials: S
authors.lastname: De Hoog
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001203:Ascomycota / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002681:China; D002862:Chromoblastomycosis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D004359:Drug Therapy, Combination; D005145:Face / Q000382:microbiology / Q000473:pathology; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage / Q000627:therapeutic use; D007868:Leg Dermatoses / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use; D000077291:Terbinafine; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D017964:Itraconazole; D000077291:Terbinafine