title: Membrane antigen expression in Epstein-Barr virus-infected Raji cells in the presence of phosphonoacetic acid.
abstract: The expression of the Epstein-Barr virus (EBV)-induced membrane antigen (MA) in Raji cells experimentally infected with EBV concentrates was inhibited by phosphonoacetic acid (PAA) as determined by membrane immunofluorescence and inhibition of antibody-dependent lymphocyte cytotoxicity. PAA was only effective if present during the first 24 hr following virus adsorption, indicating that the synthesis of MA was primarily a late viral gene function requiring viral DNA synthesis.
authors.affiliation: Department of Microbiology, Mayo Clinic, Rochester, Minnesota 55901, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Granlund
authors.forename: G R
authors.initials: GR
authors.lastname: Pearson