title: Newborn hearing screening in infants with cleft palates.
abstract: OBJECTIVE
  The high incidence of conductive hearing loss from serous effusion in patients with cleft palate is well known. This study investigates the results and interpretation of newborn hearing screening in infants with cleft palates.
  
  
  METHODS
  Retrospective cohort review.
  
  
  METHODS
  One hundred fourteen newborns with cleft palate, with or without cleft lip, born between 1999 and 2005 and referred to a craniofacial anomalies clinic.
  
  
  METHODS
  Tympanostomy tubes were placed in 102 newborns, and follow-up audiograms were available for 104 infants.
  
  
  METHODS
  Hearing screening outcomes were collected. Sex, gestational period, type of screening performed, the presence of hearing loss after tube placement, and the presence of associated syndromes were noted.
  
  
  RESULTS
  Eighty-two (72%) of 114 of newborns with cleft palates passed their hearing screen. Of the 30 newborns who failed their hearing screen, and had tympanostomy tubes placed, 13 (43%) had persistent hearing loss after tube placement. Factors predicting persistent hearing loss include cleft palate alone, female infants, and the presence of an associated syndrome.
  
  
  CONCLUSIONS
  Newborns with cleft palate are at higher risk of failing their newborn hearing screen compared with healthy neonates. Detection of sensorineural or conductive hearing loss unrelated to middle ear effusions is more difficult in this at-risk population with cleft palate because of the high prevalence of serous otitis media.
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Children's Hospital, Boston, Massachusetts, USA.
authors.forename: Judy L
authors.initials: JL
authors.lastname: Chen
authors.forename: Anna H
authors.initials: AH
authors.lastname: Messner
authors.forename: Ginny
authors.initials: G
authors.lastname: Curtin
mesh_terms: D001301:Audiometry, Pure-Tone; D002648:Child; D002675:Child, Preschool; D002972:Cleft Palate / Q000453:epidemiology*; D015331:Cohort Studies; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000453:epidemiology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening / Q000379:methods*; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D012189:Retrospective Studies