title: The oligoribonuclease gene in Streptomyces coelicolor is not transcriptionally or translationally coupled to adpA, a key bldA target.
abstract: Transcriptional analysis of the gene in Streptomyces coelicolor encoding oligoribonuclease indicates that it is not transcriptionally or translationally coupled to adpA, a key bldA target for morphological differentiation. Interestingly, construction and phenotypic analysis of an S. coelicolor oligoribonuclease null mutant revealed a conditional defect in morphological differentiation that is reminiscent of bldA and other known developmental mutants.
authors.affiliation: Department of Molecular Microbiology, John Innes Centre, Norwich, UK. jason_sello@brown.edu
authors.forename: Jason K
authors.initials: JK
authors.lastname: Sello
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Buttner
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D005095:Exoribonucleases / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D014176:Protein Biosynthesis; D012329:RNA, Bacterial / Q000235:genetics / Q000378:metabolism*; D012356:RNA, Transfer, Leu / Q000235:genetics / Q000378:metabolism*; D048372:Streptomyces coelicolor / Q000166:cytology / Q000201:enzymology* / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; C107344:BldA tRNA, Streptomyces coelicolor; D012329:RNA, Bacterial; D012356:RNA, Transfer, Leu; D005095:Exoribonucleases; C094587:oligoribonuclease