title: Poriacosones A and B: two new lanostane triterpenoids from Poria cocos.
abstract: Two new lanostane triterpenoids, poriacosones A (8) and B (9), together with eight known compounds were isolated from the sclerotia of Poria cocos (Schw.) Wolf (Polyporaceae), and identified by spectroscopic analysis, including IR, UV, CD, ESI-TOF-MS, HR-SIMS, 1D-, and 2D-NMR spectra. The structures of the new compounds were established as 3alpha,16alpha-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (8) and 3beta,16alpha-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (9).
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xiu-Wei
authors.initials: XW
authors.lastname: Yang
mesh_terms: D000818:Animals; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D020072:Polyporales / Q000737:chemistry*; D011817:Rabbits; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D010975:Platelet Aggregation Inhibitors; D014315:Triterpenes; C532681:poriacosone A; C532682:poriacosone B