Double emulsion templated monodisperse phospholipid vesicles.
We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids.
Shum
Ho Cheung
HC
School of Engineering and Applied Sciences and Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.
Lee
Daeyeon
D
Yoon
Insun
I
Kodger
Tom
T
Weitz
David A
DA
D004655:Emulsions; D010316:Particle Size; D010743:Phospholipids / Q000737:chemistry*
D004655:Emulsions; D010743:Phospholipids