title: MultiHance in MRA of peripheral vasculature.
abstract: Magnetic resonance angiography (MRA) is a cost effective technique able to detect and quantify stenoses, provide sub-millimeter resolution with full arterial coverage, and show true vessel delineation without artifacts.The quality of images obtained with gadolinium-enhanced MRA depends on the gradient system, coil, sequence design, and contrast agent (volume, dose and injection rate). MRA protocols are evolving from standard k-space sampling (linear from the periphery or the center) to elliptic centric view ordering and to time-resolved MRA. Finally, the gadolinium-based contrast agent Gd-BOPTA (gadobenate dimeglumine, MultiHance; Bracco Imaging, Milan, Italy) offers considerably greater imaging efficacy compared to conventional gadolinium chelates,because identical results can be obtained at lower doses. In conclusion, MRA of the peripheral vasculature is a simple and fast technique, which permits evaluation of a large field of view without risk of radiation exposure.
authors.affiliation: Department of Radiology, Hôpital Cardiovasculaire et Pneumologique, Louis Pradel, 28 rue du Doyen Lepiné, 69394 Lyon Cedex 3, France. philippe.douek@creatis.univ-lyon1-fr
authors.forename: Philippe C
authors.initials: PC
authors.lastname: Douek
mesh_terms: D003287:Contrast Media; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008536:Meglumine / Q000031:analogs & derivatives*; D009942:Organometallic Compounds; D016491:Peripheral Vascular Diseases / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine