Multiple sequence alignments as tools for protein structure and function prediction.
Multiple sequence alignments have much to offer to the understanding of protein structure, evolution and function. We are developing approaches to use this information in predicting protein-binding specificity, intra-protein and protein-protein interactions, and in reconstructing protein interaction networks.
Valencia
Alfonso
A
Protein Design Group, National Centre for Biotechnology, CNB-CSIC, Madrid, Spain. valencia@cnb.uam.es