title: Anaesthesia for caesarean section in a patient with  Ehlers-Danlos syndrome associated with postural orthostatic  tachycardia syndrome.
abstract: We report the use of regional anaesthesia for elective caesarean section in a primigravida with hypermobility type Ehlers-Danlos syndrome (type III) associated with postural orthostatic tachycardia syndrome. Single-shot spinal anaesthesia was performed after failed epidural anaesthesia. This genotype, although generally associated with fewer antenatal and peripartum complications, is more likely than other types to display dysautonomia and orthostatic intolerance. This requires careful management for delivery.
authors.affiliation: Department of Anaesthetics, Whittington Hospital, London, UK. tljdoc@aol.com
authors.forename: T L
authors.initials: TL
authors.lastname: Jones
authors.forename: C
authors.initials: C
authors.lastname: Ng
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D004535:Ehlers-Danlos Syndrome / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D054972:Postural Orthostatic Tachycardia Syndrome / Q000209:etiology / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*