Neutralization of lethality and proteolytic activities of Malayan pit viper (Calloselasma rhodostoma) venom with North American Virginia opossum (Didelphis virginiana) serum.
Malayan pit viper (Calloselasma rhodostoma) envenomation is a major health problem in South East Asia. During envenomation, venom components mainly affect the hemostatic system. The sera from the North American Virginia opossums (Didelphis virginiana) were able to neutralize the venom of the Malayan pit viper. These natural inhibitors could be explored as potential therapeutics against envenomations of a variety of venomous snake species in different geographical habitats.
Pornmanee
Piboon
P
Program of Biotechnology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Sánchez
Elda E
EE
López
Gonzalo
G
Petsom
Amorn
A
Khow
Orawan
O
Pakmanee
Narumol
N
Chanhome
Lawan
L
Sangvanich
Polkit
P
Pérez
John C
JC
D000818:Animals; D003435:Crotalid Venoms / Q000037:antagonists & inhibitors*; D048293:Didelphis / Q000097:blood*; D007928:Lethal Dose 50
D003435:Crotalid Venoms