Analysis of acrylamide in a complex matrix of polyacrylamide solutions treated by heat and ultraviolet light.
A recently developed headspace/solid-phase microextraction/gas chromatograph (GC) equipped with a nitrogen-phosphorus detector (NPD) (HS/SPME/GC/NPD) method was used to analyze acrylamide formed in an aqueous polyacrylamide solution (25%) treated by heat or photo-irradiation. Original polyacrylamide contained 0.43 +/- 0.11 microg/mL of acrylamide. When polyacrylamide solution was heated at 70 degrees C for 16 h with 0.5% potassium persulfate, the amount of acrylamide increased to 1.02 +/- 0.11 microg/mL. When polyacrylamide solution was irradiated by UV (lambda = 300 nm) for 16 h with 0.05% 2-anthraquinone sulfate sodium salt, the amount of acrylamide increased to 1.14 +/- 0.54 microg/mL. Polyacrylamide has been used in cosmetic formulations. The present study, therefore, suggests that there is another route of acrylamide exposure to humans in addition to foods and beverages.
Ishizuka
Mayumi
M
Department of Environmental Toxicology, University of California, Davis, California 95616, USA.
Fujioka
Kazutoshi
K
Shibamoto
Takayuki
T
D020106:Acrylamide / Q000032:analysis*; D000180:Acrylic Resins / Q000737:chemistry*; D002849:Chromatography, Gas; D003358:Cosmetics / Q000737:chemistry; D006358:Hot Temperature; D012996:Solutions; D014466:Ultraviolet Rays; D000099166:Polyacrylamides
D020106:Acrylamide; D000180:Acrylic Resins; D003358:Cosmetics; D012996:Solutions; D000099166:Polyacrylamides