title: Viral interference in feline leukemia-sarcoma complex.
abstract: Feline leukemia viruses replicate in feline embryo fibroblast cultures without causing visible effects. The virus-infected cultures acquire a resistance to superinfection with the closely related focus-forming feline leukemia pseudotypes of murine sarcoma virus and the feline sarcoma viruses. This induction of viral interference in tissue cultures with the cell-transforming effects of the challenge viruses can be used as a quantitative in vitro assay for the detection of feline leukemia viruses. Preliminary observations indicate that the interference is virus strain-specific (type-specific) and suggest the existence of distinct differences in viral envelope characteristics demonstrable in the viral interference tests.
authors.affiliation: National Cancer Institute, Bethesda, Maryland 20014, USA.
authors.forename: P S
authors.initials: PS
authors.lastname: Sarma
authors.forename: T
authors.initials: T
authors.lastname: Log