Microbial production of fructosyltransferases for synthesis of pre-biotics.
Fructooligosaccharides (FOS) are prebiotic substances found in several vegetable or natural foods. The main commercial production of FOS comes from enzymatic transformation of sucrose by the microbial enzyme fructosyltransferase. The development of more efficient enzymes, with high activity and stability, is required and this has attracted the interest of biotechnologists and microbiologists with production by several microorganisms being studied. This article reviews and discusses FOS chemical structure, enzyme characteristics, the nomenclature, producer microorganisms and enzyme production both in solid state fermentation and submerged cultivation.
Maiorano
Alfredo Eduardo
AE
Laboratório de Biotechnologia Industrial, Instituto de Pesquisas Tecnológicas do Estado de São Paulo-IPT, Av. Prof. Almeida Prado 532, 05508-901, Sao Paulo, Brazil.
Piccoli
Rosane Moniz
RM
da Silva
Elda Sabino
ES
de Andrade Rodrigues
Maria Filomena
MF
D001230:Aspergillus / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D005285:Fermentation; D006602:Hexosyltransferases / Q000378:metabolism*; D007218:Industrial Microbiology / Q000379:methods; D009844:Oligosaccharides / Q000737:chemistry* / Q000378:metabolism*; D001426:Bacterial Proteins
D006602:Hexosyltransferases; D009844:Oligosaccharides; C116580:fructooligosaccharide; C021451:inulosucrase; D001426:Bacterial Proteins