title: Sequence and phylogenetic analysis of a Chinese very virulent infectious bursal disease virus.
abstract: The complete genome sequence of a Chinese very virulent infectious bursal disease virus (vvIBDV) strain, Harbin-1, was determined. Based on the sequence analysis, the molecular characteristics and potential virulence determinants and origin of vvIBDV strains were identified. Phylogenetic analysis indicated that a reassortment and/or recombination event may have occurred in the emergence of Chinese vvIBDV strains.
authors.affiliation: Laboratory for Animal Molecular Virology, Department of Molecular Biology and Biochemistry, College of Biological Science, China Agricultural University, 100094 Beijing, China.
authors.forename: R X
authors.initials: RX
authors.lastname: Xia
authors.forename: H Y
authors.initials: HY
authors.lastname: Wang
authors.forename: G M
authors.initials: GM
authors.lastname: Huang
authors.forename: M F
authors.initials: MF
authors.lastname: Zhang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018175:Birnaviridae Infections / Q000662:veterinary* / Q000821:virology; D002645:Chickens; D002681:China; D007243:Infectious bursal disease virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D008969:Molecular Sequence Data; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology*; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D016865:Reassortant Viruses; D011995:Recombination, Genetic; D014774:Virulence
chemical_list: D012367:RNA, Viral