title: Cranial vault metastasis of giant cell tumor.
abstract: Giant cell tumors are benign bony tumors involving the epiphysis of long bones. Here, we present a case of giant cell tumor involving the parietal bone that had metastasized from the sacrum. A 36-year-old healthy woman presented to neurosurgery clinic in April 2005 reporting a "bump" over the left parietal area that had been increasing in size over the past 6 months. The lesion was nontender, and the patient had no other associated neurological symptoms. As we have presented here, cranial vault metastases can occur and should be considered in a differential diagnosis of bony lesions found in this location. These distant metastases, although relatively uncommon, must be managed aggressively. Newer radiation treatments seem to be a promising favorable adjunct to wide local resection and should be investigated further for these tumors.
authors.affiliation: Department of Neurosurgery, Louisiana State University Health Sciences Center in Shreveport, PO Box 33932, Shreveport, LA 71130-39392, USA.
authors.forename: Christina
authors.initials: C
authors.lastname: Notarianni
authors.affiliation: Department of Neurosurgery, Louisiana State University Health Sciences Center in Shreveport, PO Box 33932, Shreveport, LA 71130-39392, USA.
authors.forename: Fluerette
authors.initials: F
authors.lastname: Abreo
authors.affiliation: Department of Neurosurgery, Louisiana State University Health Sciences Center in Shreveport, PO Box 33932, Shreveport, LA 71130-39392, USA. Electronic address: ananda@lsuhsc.edu.
authors.forename: Anil
authors.initials: A
authors.lastname: Nanda
mesh_terms: D000328:Adult; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000473:pathology*; D006801:Humans; D010294:Parietal Bone / Q000473:pathology*; D012447:Sacrum / Q000473:pathology*; D012888:Skull Neoplasms / Q000556:secondary*; D013125:Spinal Neoplasms / Q000473:pathology*