Copper-mediated C-H bond arylation of arenes with arylboronic acids.
A new copper-mediated cross-coupling of arenes and arylboronic acids is described. Under the influence of Cu(OCOCF 3) 2, the C-H bond arylation of electron-rich arenes with arylboronic acids takes place to afford a range of biaryls in good yields. The reaction is selective for cross-coupling; no homocoupling product arising from arenes or arylboronic acids is detected. Multiple C-H bond arylation is possible with indoles and pyrroles furnishing interesting extended pi-systems.
Ban
Ikuya
I
Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
Sudo
Tomoko
T
Taniguchi
Tadashi
T
Itami
Kenichiro
K
D001897:Boronic Acids / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D001897:Boronic Acids; D006841:Hydrocarbons, Aromatic; D009942:Organometallic Compounds; D003300:Copper