Anaplastic large-cell T-cell lymphoma.
A 64-year-old woman presented with 2 years of pruritic and ulcerated nodules and tumors on the trunk and arms. Histopathologic examination showed a diffuse infiltrate that consisted of predominantly small lymphocytes and scattered large atypical multinucleated cells positive for CD30. These findings were consistent with a diagnosis of anaplastic large-cell T-cell lymphoma, which is a CD30+ cutaneous lymphoma. This case highlights the importance of considering both histopathologic and clinical criteria in diagnosing a patient with a CD30+ cutaneous lymphoma.
Stein
Jennifer A
JA
Department of Dermatology, New York University, USA.
Soldano
Anthony C
AC
Latkowski
Jo-Ann M
JA
D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017730:Ki-1 Antigen / Q000276:immunology; D054446:Lymphoma, Primary Cutaneous Anaplastic Large Cell / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*
D017730:Ki-1 Antigen