HIV and obstetric complications and fetal outcomes in Vellore, India.
Antenatal prevalence is more than 1% in parts of India, yet little is known about the complications and fetal outcomes in this region. We reviewed the records of 23,386 women who delivered at the Christian Medical College Hospital in Vellore, India from 2000 through 2002. HIV-infected women were more likely than HIV-uninfected women to have pregnancy-induced hypertension, anaemia, breech presentations, stillborn babies and fetal deaths. HIV-infected women who did not receive mother-to-child transmission prophylaxis or had breech fetal presentation were more likely to have fetal deaths (P = 0.001). HIV prophylaxis and optimal prenatal care should be a priority for HIV-infected pregnant women in resource-limited countries.
Lionel
Jessie
J
Department of Obstetrics and Gynaecology, Christian Medical College, Vellore, India. jessielionel@cmcvellore.ac.in
Aleyamma
T K
TK
Varghese
Lilly
L
Buck
Jessica
J
Gopalakrishnan
Geetha
G
Chaguturu
Sreekanth
S
Cu-Uvin
Susan
S
Mayer
Kenneth
K
D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000517:prevention & control / Q000635:transmission / Q000821:virology; D018023:HIV Seronegativity; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008485:Medical Audit; D019829:Nevirapine / Q000627:therapeutic use; D007744:Obstetric Labor Complications / Q000453:epidemiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011295:Prenatal Care; D015215:Zidovudine / Q000627:therapeutic use
D019380:Anti-HIV Agents; D015215:Zidovudine; D019829:Nevirapine