Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.
We report the preparation of organometallic Pd(allyl) dinuclear complexes in protein cages of apo-Fr by reactions with [Pd(allyl)Cl]2 (allyl = eta3-C3H5). One of the dinuclear complexes is converted to a trinuclear complex by replacing a Pd-coordinated His residue to an Ala residue. These results suggest that multinuclear metal complexes with various coordination structures could be prepared by the deletion or introduction of His, Cys, and Glu at appropriate positions on protein surface.
Abe
Satoshi
S
Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
Niemeyer
Jochen
J
Abe
Mizue
M
Takezawa
Yusuke
Y
Ueno
Takafumi
T
Hikage
Tatsuo
T
Erker
Gerhard
G
Watanabe
Yoshihito
Y
D001052:Apoferritins / Q000737:chemistry* / Q000235:genetics; D001665:Binding Sites; D018360:Crystallography, X-Ray; D003545:Cysteine / Q000737:chemistry / Q000235:genetics; D018698:Glutamic Acid / Q000737:chemistry / Q000235:genetics; D006639:Histidine / Q000737:chemistry / Q000235:genetics; D009154:Mutation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
D009942:Organometallic Compounds; D018698:Glutamic Acid; D006639:Histidine; D010165:Palladium; D001052:Apoferritins; D003545:Cysteine