title: Predicting delayed graft function and mortality in kidney transplantation.
abstract: Kidney transplantation (KT) is the treatment of choice for end-stage renal failure, but such patients are increasingly older and have additional comorbid conditions leading to high mortality rates after transplantation. Delayed graft function is a common complication after KT, especially in recipients who receive expanded criteria donor, and these complications are associated with a poorer graft survival in the long term. Taken together, an appropriate assessment of comorbidity grouped in prognostic indexes could be a useful tool to make crucial therapeutic decisions at the time of transplant. Allocation systems based upon a recipient risk score, as well as identification of risk factors for delayed graft function, may improve outcomes after KT. The aim of this review is to assess the contribution and utility of comorbid conditions, grouped in prognostic indexes to predict and improve kidney transplant outcomes.
authors.affiliation: Department of Nephrology, Hospital Universitario de Canarias, Ofra s/n, 38320 La Laguna, Tenerife, Spain. domingohernandez@gmail.com
authors.forename: Domingo
authors.initials: D
authors.lastname: Hernández
authors.forename: Margarita
authors.initials: M
authors.lastname: Rufino
authors.forename: José Manuel
authors.initials: JM
authors.lastname: González-Posada
authors.forename: Sara
authors.initials: S
authors.lastname: Estupiñán
authors.forename: Germán
authors.initials: G
authors.lastname: Pérez
authors.forename: Domingo
authors.initials: D
authors.lastname: Marrero-Miranda
authors.forename: Armando
authors.initials: A
authors.lastname: Torres
authors.forename: Julio
authors.initials: J
authors.lastname: Pascual
mesh_terms: D015897:Comorbidity; D005544:Forecasting; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000401:mortality*; D013997:Time Factors; D016896:Treatment Outcome