Langerhans cell histiocytosis: a case report and summary of the current recommendations of the Histiocyte Society.
Langerhans cell histiocytosis (LCH) is a rare proliferative disorder in which pathological Langerhans cells (LCs) accumulate in a variety of organs. Historically, the nomenclature regarding LCH has been confusing because the disease had been sub-categorized simply based upon different clinical manifestations. Herein, we report a child with the classic finding of disseminated LCH and summarize the current recommendation of the Histiocyte Society regarding the classification, evaluation, prognosis and treatment of LCH.
Satter
Elizabeth K
EK
Department of Dermatology, Naval Medical Center, San Diego, CA, USA. Elizabeth.Satter@med.navy.mil
High
Whitney A
WA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001847:Bone Diseases / Q000000981:diagnostic imaging; D002675:Child, Preschool; D003919:Diabetes Insipidus / Q000209:etiology; D005183:Failure to Thrive / Q000209:etiology; D006646:Histiocytosis, Langerhans-Cell / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000378:metabolism; D008297:Male; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011859:Radiography; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology*; D012886:Skull / Q000000981:diagnostic imaging