title: Just the FACTs: histone H2B ubiquitylation and nucleosome dynamics.
abstract: In this issue of Molecular Cell, Fleming et al. (2008) show that histone H2B ubiquitylation and FACT function interdependently to facilitate nucleosome reassembly during transcription elongation, thereby demonstrating that histone posttranslational modifications can provide important but transient transcriptional signaling cues.
authors.affiliation: Department of MCD Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. hartzog@biology.ucsc.edu
authors.forename: Grant A
authors.initials: GA
authors.lastname: Hartzog
authors.forename: Tiffani K
authors.initials: TK
authors.lastname: Quan
mesh_terms: D002843:Chromatin / Q000378:metabolism; D006657:Histones / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism; D008745:Methylation; D009707:Nucleosomes / Q000378:metabolism*; D011485:Protein Binding; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000378:metabolism*; D014158:Transcription, Genetic; D054875:Ubiquitination
chemical_list: D002843:Chromatin; D006657:Histones; D009707:Nucleosomes; D008239:Lysine