title: The mitochondrial proteome: from inventory to function.
abstract: Mitochondria are central to cellular energetics, metabolism, and signaling. In this issue, Pagliarini et al. (2008) report the largest compendium of mammalian mitochondrial proteins to date. Together with proteomic studies in yeast, this study represents an important step toward the systematic characterization of the mitochondrial proteome and of mitochondrial diseases.
authors.affiliation: Institut für Biochemie und Molekularbiologie, ZBMZ, Universität Freiburg, 79104 Freiburg, Germany.
authors.forename: Chris
authors.initials: C
authors.lastname: Meisinger
authors.forename: Albert
authors.initials: A
authors.lastname: Sickmann
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Pfanner
mesh_terms: D000818:Animals; D006801:Humans; D013058:Mass Spectrometry; D051379:Mice; D008928:Mitochondria / Q000737:chemistry*; D024101:Mitochondrial Proteins / Q000032:analysis*; D020543:Proteome
chemical_list: D024101:Mitochondrial Proteins; D020543:Proteome