Prescribing and monitoring hemodialysis dose.
Small patients require higher Kt/V, the ratio of dialysis dose (the product of small-molecule clearance (K) and dialysis session length (t) to body water volume (V), than large patients. The errors implicit in Kt/V for judging hemodialysis dose are reviewed; methods for prescribing hemodialysis based on new technology are discussed; and thoughts about future development are suggested.
Lowrie
Edmund G
EG
Retired; Cape Neddick, Maine, USA. edlowrie@prodigy.net
D049628:Body Size; D015314:Dialysis Solutions / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008962:Models, Theoretical; D006435:Renal Dialysis / Q000379:methods* / Q000401:mortality / Q000592:standards; D015996:Survival Rate; D016896:Treatment Outcome; D014508:Urea / Q000378:metabolism
D015314:Dialysis Solutions; D014508:Urea