A combined harmonic phase and strain-encoded pulse sequence for measuring three-dimensional strain.
Measurement of myocardial strain provides direct information about heart function that can be correlated with disease. We present an MRI pulse sequence that acquires in just six heartbeats both harmonic phase (HARP) and strain-encoded (SENC) images and provides dense measurements of radial, circumferential and longitudinal strains within a single short-axis slice. Normal volunteer data confirm the feasibility of this pulse sequence, and acquired data demonstrate the strain measurement reliability.
Sampath
Smita
S
Image Analysis and Communications Laboratory, Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD 21218, USA. smita.sampath@yale.edu
Osman
Nael F
NF
Prince
Jerry L
JL
D000328:Adult; D016477:Artifacts; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009200:Myocardial Contraction / Q000502:physiology*