Blood cells contribute to glial repair in an insect.
Using antibodies specific for haemocytes, we have shown that these blood cells penetrate the abdominal nervous connectives of the cockroach following selective disruption of the glia using the DNA-intercalating drug, ethidium bromide, as a glial toxin. Within 4 days post-lesion, the labelled cells formed a mosaic beneath the neural lamella and penetrated deeply among the disrupted subperineurial glia. These observations confirm that exogenous cells are involved in glial repair and support a previous hypothesis that they play critical roles in both structural repair and the recruitment of endogenous reactive cells.
Howes
E A
EA
Zoology Department, University College, London WC1E 6BT, U.K.
Chain
B M
BM
Smith
P J
PJ
Treherne
J E
JE