title: Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives.
abstract: Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.
authors.affiliation: Inserm U558, F-31073Toulouse, France. rolland.y@chu-toulouse.fr
authors.forename: Y
authors.initials: Y
authors.lastname: Rolland
authors.forename: S
authors.initials: S
authors.lastname: Czerwinski
authors.forename: G
authors.initials: G
authors.lastname: Abellan Van Kan
authors.forename: J E
authors.initials: JE
authors.lastname: Morley
authors.forename: M
authors.initials: M
authors.lastname: Cesari
authors.forename: G
authors.initials: G
authors.lastname: Onder
authors.forename: J
authors.initials: J
authors.lastname: Woo
authors.forename: R
authors.initials: R
authors.lastname: Baumgartner
authors.forename: F
authors.initials: F
authors.lastname: Pillard
authors.forename: Y
authors.initials: Y
authors.lastname: Boirie
authors.forename: W M C
authors.initials: WM
authors.lastname: Chumlea
authors.forename: B
authors.initials: B
authors.lastname: Vellas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D016330:Frail Elderly; D006801:Humans; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000502:physiology / Q000503:physiopathology*; D009133:Muscular Atrophy / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000517:prevention & control