A lethal form of Gorham disease associated with extensive musculoskeletal pneumatosis: case report and review of the literature.
We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death.
Atalabi
Omolola M
OM
Department of Radiology, College of Medicine, University College Hospital, Ibadan, Ibadan, Oyo State, Nigeria.
Fishman
Steven J
SJ
Kozakewich
Harry P
HP
Alsamarah
Ali Y
AY
Alomari
Ahmad I
AI
D000293:Adolescent; D002916:Chylothorax / Q000209:etiology; D003937:Diagnosis, Differential; D018450:Disease Progression; D004646:Emphysema / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010015:Osteolysis, Essential / Q000150:complications / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed