[A case of simultaneous hepatic metastases of ascending colon cancer responding completely to tegafur/uracil plus oral Leucovorin therapy after primary lesion resection].
An 81-year-old woman, who suffered from ascending colon cancer with liver metastases, underwent right hemicolectomy. She did not undergo liver resection due to her age and her family's decision, and was treated with UFT plus oral Leucovorin therapy. The metastases were remarkably reduced in the early phase and disappeared completely on SPIO-MRI 2 years 9 months later. Adverse effects of this therapy are relatively few, and it can serve as first-line chemotherapy for advanced colorectal cancer.
Tomimatsu
Hiroaki
H
Dept. of Surgery, Chichibu Municipal Hospital.
Nakano
Tatsuya
T
D000284:Administration, Oral; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D005641:Tegafur / Q000627:therapeutic use*; D014498:Uracil / Q000627:therapeutic use*
D005641:Tegafur; D014498:Uracil; D002955:Leucovorin