Heparin is procoagulant in the absence of antithrombin.
Smith
Stephanie A
SA
Morrissey
James H
JH
D000818:Animals; D000991:Antithrombins / Q000172:deficiency*; D001777:Blood Coagulation / Q000187:drug effects*; D003029:Coagulants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D017984:Enoxaparin / Q000494:pharmacology*; D015943:Factor Va / Q000378:metabolism; D015951:Factor Xa / Q000378:metabolism; D015844:Heparin Cofactor II / Q000378:metabolism; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D011122:Polyphosphates / Q000494:pharmacology; D013917:Thrombin / Q000378:metabolism
D000991:Antithrombins; D003029:Coagulants; D017984:Enoxaparin; D008074:Lipoproteins; D011122:Polyphosphates; C051928:lipoprotein-associated coagulation inhibitor; D015943:Factor Va; D015844:Heparin Cofactor II; D013917:Thrombin; D015951:Factor Xa