title: Familial myeloma.
abstract: We describe a family with five cases of multiple myeloma, three cases of monoclonal gammopathy of undetermined significance (MGUS), and five cases of prostate cancer in two generations. The putative progenitor had progeny with two female partners. The progeny had prostate cancer, multiple myeloma, and MGUS.
authors.affiliation: Creighton University School of Medicine, Omaha, USA.
authors.forename: Henry T
authors.initials: HT
authors.lastname: Lynch
authors.forename: Kelly
authors.initials: K
authors.lastname: Ferrara
authors.forename: Bart
authors.initials: B
authors.lastname: Barlogie
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Coleman
authors.forename: Jane F
authors.initials: JF
authors.lastname: Lynch
authors.forename: Dennis
authors.initials: D
authors.lastname: Weisenburger
authors.forename: Warren
authors.initials: W
authors.lastname: Sanger
authors.forename: Patrice
authors.initials: P
authors.lastname: Watson
authors.forename: Henry
authors.initials: H
authors.lastname: Nipper
authors.forename: Vinetta
authors.initials: V
authors.lastname: Witt
authors.forename: Stephan
authors.initials: S
authors.lastname: Thomé
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044383:Black People / Q000235:genetics; D005260:Female; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D007146:Immunoglobulin lambda-Chains / Q000097:blood; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary; D010265:Paraproteinemias / Q000097:blood / Q000235:genetics* / Q000276:immunology; D010375:Pedigree; D011471:Prostatic Neoplasms / Q000235:genetics*
chemical_list: D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains