WCAFTI: worrisome cytologic alterations following tissue infarction; a mimicker of malignancy in breast cytology.
The acronym WCAFTI (cafti)-(Worrisome cytologic alterations following tissue infarction) is introduced here for the first time for the entity which describes the spectrum of cytologic changes seen in spontaneous infarction of an epithelial lesion. The pathology may be responsible for abnormal cytologic findings such as cellular dyshesiveness, nuclear enlargement with cytoplasmic blurring and irregular nuclei. Although, it is a rare event, it is essential for a cytologist to be aware of this new acronym WCAFTI to avoid misinterpretation of atypical cells and necrosis as indicators of malignancy. It is typically described here in a fibroadenoma from a 49-year-old female who sought medical help for pain in left breast mass.
Kavdia
Reeti
R
Department of Pathology, St. John's Medical College and Hospital, Bangalore 560034, India.
Kini
Usha
U
D000818:Animals; D001943:Breast Neoplasms / Q000098:blood supply* / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007238:Infarction; D008875:Middle Aged