title: [Primary hyperparathyroidism as a differential diagnosis of Creutzfeldt-Jakob disease].
abstract: We report the case of a 79-years-old woman, hospitalized for a suspicion of Creutzfeldt-Jakob disease because of subacute dementia associated with gait disorder. Laboratory testing revealed elevated serum calcium at 3.51 mmol/l (N=2.25-2.60 mmol/l) caused by a hyperparathyroidism. After symptomatic treatment of hypercalcemia by biphosphonate, cognitive functions as well as the gait disorder improved quickly. A double parathyroid adenoma was removed surgically. Primary hyperparathyroidism is a curable cause of a Creutzfeldt-Jakob like syndrome. Serum calcium should be checked in this clinical setting.
authors.affiliation: Service de Neurologie, Hôpital A-Mignot, Centre Hospitalier de Versailles, 1 Rue Richaud, 78000 Versailles, France.
authors.forename: M-L
authors.initials: ML
authors.lastname: Chadenat
authors.forename: M-A
authors.initials: MA
authors.lastname: Dalloz
authors.forename: J
authors.initials: J
authors.lastname: D'Anglejean
authors.forename: F
authors.initials: F
authors.lastname: Fineyre
authors.forename: F
authors.initials: F
authors.lastname: Pico
mesh_terms: D000368:Aged; D002118:Calcium / Q000097:blood; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D003704:Dementia / Q000209:etiology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D020235:Gait Apraxia / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D049950:Hyperparathyroidism, Primary / Q000097:blood / Q000209:etiology*
chemical_list: D002118:Calcium