title: Transient isolated lesion of the splenium associated with clinically mild influenza encephalitis.
abstract: Transient isolated lesions of the splenium with restricted diffusion are rare in the pediatric population. We report two such cases with influenza-associated encephalitis/encephalopathy (IAEE). These reversible isolated central splenial lesions are not specific for IAEE, but the notable feature associated with this specific presentation is a comparatively milder form of encephalitis that resolves clinically and radiologically within a short time.
authors.affiliation: Department of Radiology and Medical Imaging, Dayton Children's Medical Center, Dayton, OH 45404, USA. ganapathys@childrensdayton.org
authors.forename: Srinivas
authors.initials: S
authors.lastname: Ganapathy
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Ey
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Wolfson
authors.forename: Nadir
authors.initials: N
authors.lastname: Khan
mesh_terms: D002648:Child; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D018792:Encephalitis, Viral / Q000175:diagnosis*; D006801:Humans; D007251:Influenza, Human / Q000175:diagnosis*; D008297:Male; D012075:Remission, Spontaneous