title: [Evolution in the epidemiology of non-variceal upper digestive hemorrhage from 1985 to 2006].
abstract: OBJECTIVE
  to describe changes occurred in the characteristics of patients suffering from non-variceal upper gastrointestinal bleeding, and in this condition s epidemiology.
  
  
  METHODS
  a prospective study was carried out to examine the occurrence and causes of non-variceal upper digestive bleeding in the corresponding health department at Virgen de las Nieves Hospital in Granada, Spain. In this study three periods of time were compared. Group 1 (1985): 284 patients; group 2 (1996): 259 patients; and group 3 (2006) 291 patients.
  
  
  RESULTS
  in group 1 the incidence was 71/100,000 inhabitants; in group 2, 64/100,000; and in group 3, 66/100,000. Mean age in 1985 was 57.4; in 1996, 59.6; and in 2006, 62.38. In all groups a majority of cases were men (75.4, 69.5, and 72.2%, respectively). Major causes included duodenal ulcer (1: 40.5%; 2: 43.2%; 3: 40.5%), gastric ulcer (1: 24.3%; 2: 30%; 3: 18.9%); LAMG (1: 53.3%; 2: 43.2%; 3: 9.6%); neoplasia (1: 1.7%; 2: 1.9%; 3: 5.2%), and vascular injuries (1: 0.5%; 2: 1.5%; 3: 9.3%). The death rate was 2.5% in 1985; 1.5% in 1996; and 1% in 2006.
  
  
  CONCLUSIONS
  a significant increase in mean age over the years was detected. The most frequent cause of hemorrhage was duodenal ulcer followed by gastric ulcer. Of significance is an increase in the proportion of neoplasms above of vascular injuries in the later group as apposed to the earlier one. We found no significant difference in mortality between groups.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Virgen de las Nieves, Granada. juradohernandez@terra.es
authors.forename: A M
authors.initials: AM
authors.lastname: Jurado Hernández
authors.forename: J
authors.initials: J
authors.lastname: de Teresa Galván
authors.forename: M
authors.initials: M
authors.lastname: Ruiz-Cabello Jiménez
authors.forename: L M
authors.initials: LM
authors.lastname: Pinel Julián
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors