[Severe phenotypes in sarcoidosis pulmonary involvement].
Severe forms of pulmonary sarcoidosis are not frequent and include stage IV pulmonary involvement and specific complications of intrathoracic sarcoidosis. Pulmonary hypertension may be due to granulomatous involvement of vessels and/or extrinsic compression of pulmonary arteries by enlarged lymph nodes. Bronchial stenosis is rare and delay in therapy usually result in corticoresistance. Mycetomas may develop in cystic spaces and be responsible for severe haemoptysis. A better knowledge of these patterns is associated with a better management of severe sarcoidosis.
Wallaert
Benoît
B
Service de pneumologie et immunoallergologie, centre de compétence des maladies orphelines pulmonaires, clinique des maladies respiratoires, hôpital Albert-Calmette, CHRU de Lille, Université Lille-II, 59037 Lille Cedex, France. bwallaert@chru-lille.fr
D001228:Aspergillosis / Q000150:complications; D001982:Bronchial Diseases; D003251:Constriction, Pathologic; D015769:Granuloma, Respiratory Tract / Q000150:complications / Q000473:pathology; D006801:Humans; D010641:Phenotype; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D012720:Severity of Illness Index