[Chemical constituents from sea cucumber Holothuria nobilis].
OBJECTIVE
To study the chemical constituents of sea cucumber Holothuria hilla L..


METHODS
Compounds were isolated from the sea cucumber by multi-chromatography on Si gel, ODS Rp C-18 gel, DA101 resin, Sephadex LH-20 and HPLC. The structures were elucidated according to their spectral data and chemical character.


RESULTS
Four compounds were isolated from the sea cucumber, and were identified as: holothuria A (I), thymine (II), uracil (III), cholesterol (IV).


CONCLUSIONS
Compounds I IV are obtained from this kind of sea cucumber for the first time.
Zhang
Jia-Jia
JJ
Zhejiang Pharmaceutical College, Ningbo 315200, China. zjj@zjbti.net.cn
Dai
Jing-Bo
JB
Chen
Li-Li
LL
Ding
Ping-Yue
PY
Wu
Jun
J
D000818:Animals; D002784:Cholesterol / Q000737:chemistry / Q000302:isolation & purification; D047332:Holothuria / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013941:Thymine / Q000737:chemistry / Q000302:isolation & purification*; D014498:Uracil / Q000737:chemistry / Q000302:isolation & purification
D012503:Saponins; D014498:Uracil; D002784:Cholesterol; D013941:Thymine