title: [Abdominal aortic involvement in active giant cell (temporal) arteritis: a study of 20 patients by Doppler ultrasonography and computed tomographic angiography].
abstract: OBJECTIVE
  This study used Doppler ultrasonography and computed tomographic angiography (CTA) to assess the prevalence of abdominal aortic lesions that suggested abdominal aortitis at diagnosis of giant-cell or temporal arteritis (GCA). We also evaluated the contribution of these 2 techniques to diagnosis.
  
  
  METHODS
  This single-center study included patients admitted to the internal medicine department of the Nantes (France) University Hospital, between May 1999 and May 2002 at the time of their diagnosis with biopsy-proven GCA. In the 8 weeks after diagnosis, patients underwent a thorough workup, including the collection of clinical and laboratory data. Imaging tests for each patient included Doppler ultrasonography and a CTA scan of the abdominal aorta, looking for aneurysms, ectasia, and thickening of the aortic wall.
  
  
  RESULTS
  This study included 20 patients (17 women, mean age 73.9+/-7.2 years, mean CRP=116+/-75.9mg/L). Doppler ultrasonography suggested aortitis in 8 cases (40%): 7 patients (35%) had a hypoechoic halo, 3 (15%) a small aneurysm (diameter < 30mm), and 2 (10%) both. CTA scans of the aorta showed aortitis in 5 cases (25%), all with abnormal thickening of the aortic wall. CTA did not identify any aneurysms. Overall, abdominal aortitis was suspected in 10 patients (50%).
  
  
  CONCLUSIONS
  At the time of GCA diagnosis, both Doppler ultrasonography and CTA can detect morphological abnormalities of the abdominal aorta. Here they suggested asymptomatic abdominal aortitis in half the patients. Doppler ultrasonography appears more effective for detecting aortic aneurysms, while CTA seems helpful for the diagnosis of parietal thickening. The risk factors associated with abdominal aortitis in GCA remain to be identified.
authors.affiliation: Service de médecine interne, CHU Hôtel-Dieu, place Alexis-Ricordeau, 44035 Nantes, Cedex 01, France. christian.agard@chu-nantes.fr
authors.forename: Christian
authors.initials: C
authors.lastname: Agard
authors.forename: Luis
authors.initials: L
authors.lastname: Said
authors.forename: Thierry
authors.initials: T
authors.lastname: Ponge
authors.forename: Jérôme
authors.initials: J
authors.lastname: Connault
authors.forename: Agathe
authors.initials: A
authors.lastname: Masseau
authors.forename: Marc-Antoine
authors.initials: MA
authors.lastname: Pistorius
authors.forename: Bernard
authors.initials: B
authors.lastname: Planchon
authors.forename: Benoît
authors.initials: B
authors.lastname: Dupas
authors.forename: Jacques H
authors.initials: JH
authors.lastname: Barrier
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Hamidou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods*; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging; D001025:Aortitis / Q000000981:diagnostic imaging; D050197:Atherosclerosis / Q000000981:diagnostic imaging; D001706:Biopsy; D002114:Calcinosis / Q000000981:diagnostic imaging; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D005260:Female; D013700:Giant Cell Arteritis / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013684:Telangiectasis / Q000000981:diagnostic imaging; D036542:Tomography, Spiral Computed; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler