title: Complete hydatidiform mole in a perimenopausal woman with a subsequent severe thyriotoxicosis.
abstract: BACKGROUND
  Gestational trophoblastic disease is one form of abnormal pregnancy, with a median maternal age of 27-28 years. One complication of trophoblastic disease is the development of a secondary hyperthyroidism, which resolves rapidly after evacuation of the hydatidiform mole.
  
  
  METHODS
  We report a case of a 53-year-old woman presenting with a complete hydatidiform mole and who developed a severe thyrotoxicosis after suction evacuation of the hydatidiform mole.
  
  
  CONCLUSIONS
  A severe thyriotoxicosis can occur even after surgical evacuation of the mole. Therefore, evaluation of the thyroid function prior to operation, especially with a high quantitative hCG, should be performed to avoid severe complications.
authors.affiliation: First Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Maistrasse 11, 80337 Munich, Germany.
authors.forename: Lena
authors.initials: L
authors.lastname: Struthmann
authors.forename: Margit
authors.initials: M
authors.lastname: Günthner-Biller
authors.forename: Florian
authors.initials: F
authors.lastname: Bergauer
authors.forename: Klaus
authors.initials: K
authors.lastname: Friese
authors.forename: Ioannis
authors.initials: I
authors.lastname: Mylonas
mesh_terms: D013956:Antithyroid Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011247:Pregnancy; D011441:Propylthiouracil / Q000627:therapeutic use; D013971:Thyrotoxicosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D014463:Ultrasonography; D014619:Vacuum Curettage
chemical_list: D013956:Antithyroid Agents; D011441:Propylthiouracil; D008727:Methotrexate