Neonatal lupus erythematosus: an acquired autoimmune disorder and its cutaneous manifestations.
Neonatal lupus erythematosus is an uncommon transplacentally acquired autoimmune disorder. The most common clinical manifestations are skin rash, congenital atrioventricular block, thrombocytopenia, leukopenia, anemia, and hepatosplenomegaly. Usually, the skin rash resembles subacute cutaneous lupus, but different forms of rash have been reported in neonatal lupus erythematosus and some are rare forms. NLE should be suspected in babies with atypical skin lesions, even if present at birth.
Gasparello-Almeida
Rozana
R
Unit of Pediatric Rheumatology, Universidade Federal do Rio de Janeiro/Instituto de Puericultura e Pediatria Martagão Gesteira, Rio de Janiero, Brazil. rozanagasp@yahoo.com.br
Feitosa-Oliveira
Sheila Knupp
SK
D001327:Autoimmune Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000503:physiopathology; D008178:Lupus Erythematosus, Cutaneous / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D012307:Risk Factors