title: Current anti-infective treatment of bacterial urinary tract infections.
abstract: Antibiotic resistance nowadays plays an important role in the treatment of uncomplicated and complicated urinary tract infections (UTIs). In uncomplicated UTI efforts are made to use antibiotic substances exclusively for this indication. In complicated UTI substances with activity against bacteria harbouring common resistance mechanisms are investigated. Additionally pharmacokinetic/ pharmacodynamic parameters are used to improve dosing strategies.
authors.affiliation: Department of Urology, Justus-Liebig-University of Giessen, Rudolf-Buchheim-Str. 7, D-35385 Giessen, Germany. Wagenlehner@AOL.com
authors.forename: Florian M E
authors.initials: FM
authors.lastname: Wagenlehner
authors.forename: Christine
authors.initials: C
authors.lastname: Wagenlehner
authors.forename: Kurt G
authors.initials: KG
authors.lastname: Naber
authors.forename: W
authors.initials: W
authors.lastname: Weidner
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000150:complications / Q000382:microbiology; D006801:Humans; D014552:Urinary Tract Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents