title: Interaction of BOP1, a protein for ribosome biogenesis, with EB1 in Giardia lamblia.
abstract: A search for a protein(s) interacting with the block of proliferation 1 (Bop1) protein of Giardia lamblia led to the isolation of end binding (EB1) protein 1, a protein that is known to function as a microtubule (MT) plus-end-tracking protein in other organisms. Interaction between Bop1 and EB1 of G. lamblia was confirmed by co-immunoprecipitation of in vitro-synthesized Bop1 and EB1 proteins. This result suggests coordination between ribosome biogenesis and cell cycle-related processes such as mitosis.
authors.affiliation: Department of Environmental Medical Biology and Institute of Tropical Medicine, Post Brain Korea 21 Program, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Juri
authors.initials: J
authors.lastname: Kim
authors.forename: Seobo
authors.initials: S
authors.lastname: Sim
authors.forename: Tai-Soon
authors.initials: TS
authors.lastname: Yong
authors.forename: Soon-Jung
authors.initials: SJ
authors.lastname: Park
mesh_terms: D000818:Animals; D016829:Giardia lamblia / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D047468:Immunoprecipitation; D008870:Microtubules / Q000378:metabolism; D008938:Mitosis; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism*; D020798:Two-Hybrid System Techniques
chemical_list: D015800:Protozoan Proteins