title: Intracameral triamcinolone acetonide as treatment for endothelial allograft rejection after penetrating keratoplasty.
abstract: OBJECTIVE
  Intracameral injection of triamcinolone acetonide as treatment of therapy-resistant endothelial allograft rejection after penetrating keratoplasty is reported.
  
  
  METHODS
  A 32-year-old patient showed conventional therapy-resistant endothelial allograft rejection 2 months after penetrating keratoplasty. The patient received an intracameral injection of 4 mg in 0.1 mL of triamcinolone acetonide. Preinjection visual acuity was count fingers at 3 ft, and the graft showed diffuse haze and multiple endothelial rejection lines.
  
  
  RESULTS
  Within 2 weeks after injection, marked resolution of the microcystic edema and reversal of the endothelial rejection was noted. Fourteen months after injection, best-corrected visual acuity was 20/20, and intraocular pressure was 17 mm Hg without antiglaucoma therapy.
  
  
  CONCLUSIONS
  Intracameral injection of triamcinolone acetonide may be an additional treatment modality in the treatment of endothelial allograft rejection when traditional steroid therapies have failed.
authors.affiliation: Department of Ophthalmology, Nassau University Medical Center, East Meadow, NY, USA. pmaris@msn.com
authors.forename: Peter J G
authors.initials: PJ
authors.lastname: Maris
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Correnti
authors.forename: Eric D
authors.initials: ED
authors.lastname: Donnenfeld
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000187:drug effects; D004728:Endothelium, Corneal / Q000473:pathology* / Q000637:transplantation; D005938:Glucocorticoids / Q000008:administration & dosage*; D006084:Graft Rejection / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D015948:Keratoplasty, Penetrating; D008297:Male; D014184:Transplantation, Homologous; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide