The neuronal basis of attention: rate versus synchronization modulation.
Extensive theoretical and experimental work on the neuronal correlates of visual attention raises two hypotheses about the underlying mechanisms. The first hypothesis, named biased competition, originates from experimental single-cell recordings that have shown that attention upmodulates the firing rates of the neurons encoding the attended features and downregulates the firing rates of the neurons encoding the unattended features. Furthermore, attentional modulation of firing rates increases along the visual pathway. The other, newer hypothesis assigns synchronization a crucial role in the attentional process. It stems from experiments that have shown that attention modulates gamma-frequency synchronization. In this paper, we study the coexistence of the two phenomena using a theoretical framework. We find that the two effects can vary independently of each other and across layers. Therefore, the two phenomena are not concomitant. However, we show that there is an advantage in the processing of information if rate modulation is accompanied by gamma modulation, namely that reaction times are shorter, implying behavioral relevance for gamma synchronization.
Buehlmann
Andres
A
Computational Neuroscience, Universitat Pompeu Fabra, 08003 Barcelona, Spain. andres.buhlmann@upf.edu
Deco
Gustavo
G
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001288:Attention / Q000187:drug effects / Q000502:physiology*; D015982:Bias; D003344:Cortical Synchronization / Q000187:drug effects; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D000882:Haplorhini; D007266:Inhibition, Psychological; D008959:Models, Neurological; D016202:N-Methylaspartate / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D013057:Spectrum Analysis; D013997:Time Factors; D014793:Visual Cortex / Q000166:cytology*; D014794:Visual Fields / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology; D014796:Visual Perception / Q000187:drug effects / Q000502:physiology*; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid / Q000494:pharmacology
D018690:Excitatory Amino Acid Agonists; D016202:N-Methylaspartate; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid