title: Immunology of mycobacterial infections: with special reference to Mycobacterium avium subspecies paratuberculosis.
abstract: The interplay between mycobacteria and host determines the outcome of infection. After uptake of mycobacteria by macrophages, several possible scenarios may emerge; mycobacteria may be destroyed immediately or there is establishment of persistent infection. This review is focused around mycobacteria-host interactions with reference to Mycobacterium avium subspecies paratuberculosis (MAP) infection and highlights protective mechanisms involved in order to design vaccines and other control strategies.
authors.affiliation: Central Institute for Research on Goats, Makhdoom, P.O. Farah, District Mathura 281122, Uttar Pradesh, India.
authors.forename: Jagdeep Singh
authors.initials: JS
authors.lastname: Sohal
authors.forename: S V
authors.initials: SV
authors.lastname: Singh
authors.forename: P
authors.initials: P
authors.lastname: Tyagi
authors.forename: Swati
authors.initials: S
authors.lastname: Subhodh
authors.forename: P K
authors.initials: PK
authors.lastname: Singh
authors.forename: A V
authors.initials: AV
authors.lastname: Singh
authors.forename: K
authors.initials: K
authors.lastname: Narayanasamy
authors.forename: Neelam
authors.initials: N
authors.lastname: Sheoran
authors.forename: Komal
authors.initials: K
authors.lastname: Singh Sandhu
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D016207:Cytokines / Q000276:immunology / Q000378:metabolism*; D003602:Cytotoxicity, Immunologic; D003713:Dendritic Cells / Q000276:immunology; D006801:Humans; D008264:Macrophages / Q000276:immunology* / Q000382:microbiology; D016927:Mycobacterium avium subsp. paratuberculosis / Q000276:immunology* / Q000472:pathogenicity; D010283:Paratuberculosis / Q000276:immunology* / Q000382:microbiology; D010587:Phagocytosis; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology / Q000378:metabolism; D051193:Toll-Like Receptors / Q000276:immunology* / Q000378:metabolism
chemical_list: D000907:Antibodies, Bacterial; D016207:Cytokines; D016692:Receptors, Antigen, T-Cell, gamma-delta; D051193:Toll-Like Receptors