title: Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia.
abstract: This study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g(2))), a spatially filtered source localization technique in magnetoencephalography (MEG), for identification of epileptogenic areas of focal cortical dysplasia (FCD). Three children with FCD were investigated to localize the ictal onset zone (IOZ). All patients subsequently had extraoperative electrocorticography (ECoG) for intractable epilepsy and surgical resection. SAM(g(2)) analysis showed overlapping of interictal MEG spike sources with the IOZ on ECoG in all children. We recommend MEG-SAM(g(2)) and MEG interictal spike source localization in patients with epileptogenic FCD.
authors.affiliation: Department of Psychiatry and Behavioral Proteomics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Ryouhei
authors.initials: R
authors.lastname: Ishii
authors.forename: Leonides
authors.initials: L
authors.lastname: Canuet
authors.forename: Ayako
authors.initials: A
authors.lastname: Ochi
authors.forename: Jing
authors.initials: J
authors.lastname: Xiang
authors.forename: Katsumi
authors.initials: K
authors.lastname: Imai
authors.forename: Derrick
authors.initials: D
authors.lastname: Chan
authors.forename: Masao
authors.initials: M
authors.lastname: Iwase
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Takeda
authors.forename: O Carter
authors.initials: OC
authors.lastname: Snead
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Otsubo
mesh_terms: D000293:Adolescent; D001931:Brain Mapping; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D054220:Malformations of Cortical Development / Q000150:complications