Resin capsules: permeable containers for parallel/combinatorial solid-phase organic synthesis.
A resin capsule is a permeable container for resin beads designed for multiple/combinatorial solid-phase organic synthesis. Resin capsules consist of a high density polyethylene ring sealed with peek mesh on both sides. The cylindrical shape of resin capsules enabled space-saving packing into plastic columnlike reaction vessels commonly used for solid-phase organic synthesis. Resin capsules have been evaluated for their use in combinatorial synthesis, and a set of model compounds with excellent purity was prepared.
Bouillon
Isabelle
I
Department of Chemistry and Biochemistry, 251 Nieuwland Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Soural
Miroslav
M
Krchnák
Viktor
V
D002625:Chemistry, Organic / Q000379:methods*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D008863:Microspheres; D011095:Polyethylenes / Q000737:chemistry; D012117:Resins, Synthetic / Q000737:chemistry*; D013499:Surface Properties
D011095:Polyethylenes; D012117:Resins, Synthetic