title: Four-component benzyne coupling reactions: a concise total synthesis of dehydroaltenuene B.
abstract: A four-component coupling reaction of 3,5-dimethoxybenzyne with 2-methyl-2-cyclohexenylmagnesium chloride, carbon dioxide, and iodine was utilized as a key step in the first total synthesis of dehydroaltenuene B.
authors.affiliation: Department of Chemistry, Imperial College London, London SW7 2AZ, England.
authors.forename: Darunee
authors.initials: D
authors.lastname: Soorukram
authors.forename: Tao
authors.initials: T
authors.lastname: Qu
authors.forename: Anthony G M
authors.initials: AG
authors.lastname: Barrett
mesh_terms: D001203:Ascomycota / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D053138:Cyclohexenes / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis*; D008274:Magnesium / Q000737:chemistry; D009183:Mycotoxins / Q000138:chemical synthesis; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D053138:Cyclohexenes; D007783:Lactones; D009183:Mycotoxins; D009942:Organometallic Compounds; C524146:benzyne; C040005:altenuene; D008274:Magnesium