Long-term follow-up of tamoxifen treatment in adolescents with gynecomastia.
Ten pubertal boys treated with tamoxifen for gynecomastia for more than 3 months were evaluated after 2.5-7 years (mean 4.6 years) to determine the side effects of this therapy. We assessed the safety of long duration in adolescents with pubertal gynecomastia treated with tamoxifen. We did not find any serious side effects of tamoxifen in these patients.
Derman
Orhan
O
Department of Pediatrics, Hacettepe University, Faculty of Medicine, Ankara, Turkey. oderman@hacettepe.edu.tr
Kanbur
Nuray
N
Kilic
Ilke
I
Kutluk
Tezer
T
D000293:Adolescent; D002648:Child; D004305:Dose-Response Relationship, Drug; D004965:Estrogen Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006177:Gynecomastia / Q000188:drug therapy*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D013629:Tamoxifen / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
D004965:Estrogen Antagonists; D013629:Tamoxifen