title: Theoretical simulation and experimental validation of inverse quasi-one-dimensional steady and unsteady glottal flow models.
abstract: In physical modeling of phonation, the pressure drop along the glottal constriction is classically assessed with the glottal geometry and the subglottal pressure as known input parameters. Application of physical modeling to study phonation abnormalities and pathologies requires input parameters related to in vivo measurable quantities commonly corresponding to the physical model output parameters. Therefore, the current research presents the inversion of some popular simplified flow models in order to estimate the subglottal pressure, the glottal constriction area, or the separation coefficient inherent to the simplified flow modeling for steady and unsteady flow conditions. The inverse models are firstly validated against direct simulations and secondly against in vitro measurements performed for different configurations of rigid vocal fold replicas mounted in a suitable experimental setup. The influence of the pressure corrections related to viscosity and flow unsteadiness on the flow modeling is quantified. The inversion of one-dimensional glottal flow models including the major viscous effects can predict the main flow quantities with respect to the in vitro measurements. However, the inverse model accuracy is strongly dependent on the pertinence of the direct flow modeling. The choice of the separation coefficient is preponderant to obtain pressure predictions relevant to the experimental data.
authors.affiliation: Department of Speech and Cognition, GIPSA-Laboratory, UMR CNRS 5216, Grenoble Universities, 961 rue de la Houille Blanche, BP 46, 38402 Saint Martin d'Heres, France. julien.cisonni@gipsa-lab.inpg.fr
authors.forename: Julien
authors.initials: J
authors.lastname: Cisonni
authors.forename: Annemie
authors.initials: A
authors.lastname: Van Hirtum
authors.forename: Xavier
authors.initials: X
authors.lastname: Pelorson
authors.forename: Jan
authors.initials: J
authors.lastname: Willems
mesh_terms: D005931:Glottis / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D008962:Models, Theoretical; D010699:Phonation / Q000502:physiology*; D015203:Reproducibility of Results