[Neuroblastoma in children].
Neuroblastomas have a very heterogenic clinical presentation, ranging from relatively benign forms with the potential of spontaneous regression, to foudroyant malignant forms. Over half of neuroblastomas must be classified as high-risk tumors with a markedly high rate of recurrence. Despite multidisciplinary therapeutic approaches, the survival rate of children with this type of tumor is still below 40%. An ever-growing amount of data from international studies dating from the early 1970s onwards, points to the necessity of re-evaluating the medical approach in establishing the diagnosis and staging, understanding tumor biology and pathology, as well as therapy planning.
Hörmann
M
M
Abteilung allgemeine Radiologie und Kinderradiologie, Medizinische Universität Wien, Währingergürtel 18-20, A-1090 Wien, Osterreich. marcus.hoermann@meduniwien.ac.at
D000293:Adolescent; D000367:Age Factors; D019046:Bone Marrow Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008017:Life Expectancy; D008279:Magnetic Resonance Imaging; D008403:Mass Screening; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000175:diagnosis; D049268:Positron-Emission Tomography; D011379:Prognosis; D011788:Quality of Life; D012307:Risk Factors; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography