title: A Mathematical model of Schistosoma mansoni in Biomphalaria glabrata with control strategies.
abstract: We describe and analyze a mathematical model for schistosomiasis in which infected snails are distinguished from susceptible through increased mortality and no reproduction. We based the model on the same derivation as Anderson and May (J. Anim. Ecol. 47:219-247, 1978), Feng and Milner (A New Mathematical Model of Schistosomiasis, Mathematical Models in Medical and Health Science, Nashville, TN, 1997. Innov. Appl. Math., Vanderbilt Univ. Press, Nashville, pp. 117-128, 1998), and May and Anderson (J. Anim. Ecol. 47:249-267, 1978), but used logistic growth both in human and snail hosts. We introduce a parameter r, the effective coverage of medical treatment/prevention to control the infection. We determine a reproductive number for the disease directly related to its persistence and extinction. Finally, we obtain a critical value for r that indicates the minimum treatment effort needed in order to clear out the disease from the population.
authors.affiliation: Department of Mathematics, Purdue University, West Lafayette, IN 47907-2067, USA.
authors.forename: Ruijun
authors.initials: R
authors.lastname: Zhao
authors.forename: Fabio Augusto
authors.initials: FA
authors.lastname: Milner
mesh_terms: D000465:Algorithms; D000818:Animals; D001700:Biomphalaria / Q000469:parasitology*; D003198:Computer Simulation; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D006790:Host-Parasite Interactions; D006801:Humans; D008954:Models, Biological; D011156:Population Density; D011157:Population Dynamics; D012550:Schistosoma mansoni / Q000502:physiology*; D012555:Schistosomiasis mansoni / Q000469:parasitology / Q000517:prevention & control* / Q000628:therapy