title: Dynamic changes in serum estradiol and progesterone levels in patients of premenstrual syndrome with adverse flow of liver-qi.
abstract: OBJECTIVE
  To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome (PMS) and reveal partial microcosmic mechanisms of adverse flow of liver-qi.
  
  
  METHODS
  Estradiol (E2) and progesterone (P) levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.
  
  
  RESULTS
  In the group of PMS with adverse flow of liver-qi, the secretive peak value of E2 and P at the follicular phase significantly decreased, and the secretive peak value at the luteal phase did not come into being.
  
  
  CONCLUSIONS
  Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi. One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2 and P.
authors.affiliation: College of Basic Medical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, China.
authors.forename: Mingqi
authors.initials: M
authors.lastname: Qiao
authors.forename: Huiyun
authors.initials: H
authors.lastname: Zhang
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Yu
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Ci
authors.forename: Xujie
authors.initials: X
authors.lastname: Xu
authors.forename: Qing
authors.initials: Q
authors.lastname: Ye
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D011293:Premenstrual Syndrome / Q000097:blood* / Q000473:pathology / Q000503:physiopathology; D011374:Progesterone / Q000097:blood*; D019413:Qi; D055815:Young Adult
chemical_list: D011374:Progesterone; D004958:Estradiol