Thiamin deficiency as a cause of reversible cor pulmonale.
Thiamine deficiency may present four classic clinical forms: peripheral polyneuropathy, anorexia and muscular weakness (dry beriberi); high output heart failure with signs of congestion (wet beriberi); beriberi associated with shock (Shoshin beriberi) and Wernicke's encephalopathy. In this report we describe a picture that is suggestive of severe pulmonary hypertension and cor pulmonale, with jugular stasis, congestive hepatitis and generalized edema that reversed completely after the administration of thiamine.
Coelho
Liana S
LS
Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brasil.
Hueb
João C
JC
Minicucci
Marcos F
MF
Azevedo
Paula S
PS
Paiva
Sergio A R
SA
Zornoff
Leonardo A M
LA
D000328:Adult; D001602:Beriberi / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D008297:Male; D011660:Pulmonary Heart Disease / Q000188:drug therapy / Q000209:etiology*; D013831:Thiamine / Q000627:therapeutic use*; D013832:Thiamine Deficiency / Q000150:complications / Q000188:drug therapy; D014803:Vitamin B Complex / Q000627:therapeutic use
D014803:Vitamin B Complex; D013831:Thiamine