title: Ketoisophorone transformation by Marchantia polymorpha and Nicotiana tabacum cultured cells.
abstract: Stereospecific olefin (C=C) and carbonyl (C=O) reduction of the readily available prochiral compound ketoisophorone (2,2,6-trimethyl-2-cyclohexene-1,4-dione) (1) by Marchantia polymorpha and Nicotiana tabacum cell suspension cultures produce the chiral products (6R)-levodione (2), (4R,5S)-4-hydroxy-3,3,5-trimethylcyclohexanone (3), and (4R,6R)-actinol (4) as well as the minor components (4R)-hydroxyisophorone (5) and (4S)-phorenol (6).
authors.affiliation: Chemistry of Medicinal Plants Department, National Research Centre, Dokki, Cairo, Egypt. elamir77@yahoo.com
authors.forename: Mohamed-Elamir F
authors.initials: ME
authors.lastname: Hegazy
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hirata
authors.forename: Ahmed
authors.initials: A
authors.lastname: Abdel-Lateff
authors.forename: Mohamed H Abd
authors.initials: MH
authors.lastname: el-Razek
authors.forename: Abou El-Hamd H
authors.initials: Ael-H
authors.lastname: Mohamed
authors.forename: Nahed M
authors.initials: NM
authors.lastname: Hassan
authors.forename: Paul W
authors.initials: PW
authors.lastname: Paré
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Mahmoud
mesh_terms: D002478:Cells, Cultured; D003512:Cyclohexanones / Q000737:chemistry / Q000378:metabolism*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D047008:Marchantia / Q000235:genetics* / Q000378:metabolism; D011110:Polymorphism, Genetic; D013057:Spectrum Analysis; D013237:Stereoisomerism; D014026:Nicotiana / Q000166:cytology* / Q000378:metabolism
chemical_list: D003512:Cyclohexanones; C476259:ketoisophorone