title: Dietary consumption of phytochemicals and breast cancer risk in Mexican women.
abstract: OBJECTIVE
  To perform an evaluation of selected phytochemicals intake and breast cancer (BC) risk in Mexican women.
  
  
  METHODS
  We conducted hospital-based case-control study.
  
  
  METHODS
  Mexico City between 1994 and 1996.
  
  
  METHODS
  A total of 141 histologically confirmed BC cases were age-matched (+/-3 years) to an equal number of hospital controls. The reproductive history of each woman was obtained by direct interview. The dietary consumption of flavonols, flavones, flavan-3-ols, cinnamic acid, lariciresinol, pinoresinol, secoisolariciresinol, matairesinol and coumestrol was obtained by means of a validated FFQ.
  
  
  RESULTS
  Among postmenopausal women, high dietary intake of flavonols and flavones was associated with a significant reduction of BC risk (high v. low tertile: OR = 0.21, 95 % CI 0.07, 0.60, P for trend = 0.004 and OR = 0.29, 95 % CI 0.10, 0.82, P for trend = 0.025, respectively); consumption of lignans (lariciresinol and pinoresinol) showed a similar effect, but only among premenopausal women (high v. low tertile: OR = 0.32, 95 % CI 0.10, 0.99, P for trend = 0.051 and OR = 0.19, 95 % CI 0.06, 0.62, P for trend = 0.006, respectively).
  
  
  CONCLUSIONS
  Our results support a protective role of specific dietary phytochemicals in BC risk by menopausal status, independent of other reproductive factors.
authors.affiliation: Instituto Nacional de Salud Pública, Av. Universidad No. 655, Col. Sta. María Ahuacatitlán, CP 62508, Cuernavaca, Morelos, Mexico.
authors.forename: Luisa
authors.initials: L
authors.lastname: Torres-Sanchez
authors.forename: Marcia
authors.initials: M
authors.lastname: Galvan-Portillo
authors.forename: Mary S
authors.initials: MS
authors.lastname: Wolff
authors.forename: Lizbeth
authors.initials: L
authors.lastname: Lopez-Carrillo
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D016022:Case-Control Studies; D004032:Diet; D004034:Diet Surveys; D005247:Feeding Behavior; D005260:Female; D047309:Flavones / Q000008:administration & dosage; D044948:Flavonols / Q000008:administration & dosage; D006801:Humans; D017705:Lignans / Q000008:administration & dosage; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D048789:Phytoestrogens / Q000008:administration & dosage*; D010840:Phytosterols / Q000008:administration & dosage; D017698:Postmenopause; D017697:Premenopause; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D047309:Flavones; D044948:Flavonols; D017705:Lignans; D048789:Phytoestrogens; D010840:Phytosterols