[Thermosensitive polymers in drug form technology. I. Classification and characteristics].
The following presentation is a review of literature related to application of thermosensitive polymers in technology of drug form. In this review described the classsification and examples of this polymers. Thermosensitive drug delivery can be used as substances carriers, which are applied in oral system, vaginal systems of release, applied on skin, the rectal, nasal, passed to eyes and parenteral. Sol-gel transition of the prepared formulations at physiological temperature ranges of the body makes possible their application in the liquid state and subsequent gelification in situ providing a prolonged release of the active substance at the application site.
Pluta
Janusz
J
Katedra i Zakład Technologii Postaci Leku Akademia Medyczna im. Piastów Slaskich, Wrocław.
Karolewicz
Bozena
B
D001704:Biopolymers / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D004333:Drug Administration Routes; D004337:Drug Carriers / Q000737:chemistry* / Q000145:classification*; D044367:Phase Transition; D011108:Polymers / Q000737:chemistry* / Q000145:classification*; D013329:Structure-Activity Relationship; D013696:Temperature
D001704:Biopolymers; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D011108:Polymers