A case of prolonged seizure after ECT in a patient treated with clomipramine, lithium, L-tryptophan, quetiapine, and thyroxine for major depression.
Electroconvulsive therapy (ECT) is indicated for the treatment of severe treatment refractory depression in many countries. It is associated with a low risk of morbidity and mortality. It is usual for high doses of psychotropic medications to be prescribed concomitantly with ECT, although published data on the interactions of these with ECT is lacking. Here, we present the case of a middle-aged woman on multiple psychotropic medications who went into status epilepticus for 45 minutes after ECT.
Rucker
James
J
South London and Maudsley NHS Foundation Trust, London, UK. james.rucker@doctors.org.uk
Cook
Marilyn
M
D000339:Affect; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000627:therapeutic use; D018692:Antimanic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002997:Clomipramine / Q000009:adverse effects* / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003865:Major Depressive Disorder / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D003987:Dibenzothiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D018020:Lithium Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D000069348:Quetiapine Fumarate; D012008:Recurrence; D013226:Status Epilepticus / Q000139:chemically induced / Q000209:etiology* / Q000523:psychology; D013974:Thyroxine / Q000009:adverse effects* / Q000627:therapeutic use; D014364:Tryptophan / Q000009:adverse effects* / Q000627:therapeutic use
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D018692:Antimanic Agents; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D018020:Lithium Compounds; D000069348:Quetiapine Fumarate; D014364:Tryptophan; D002997:Clomipramine; D013974:Thyroxine