title: The use of tissue electrical characteristics for breast cancer detection: a perspective review.
abstract: Breast cancer is the most frequently occurring malignancy in women. It is characterized by a high mortality rate. For the purpose of detecting this life threatening disease, research efforts are being made worldwide to exploit new technologies, to improve the detection accuracy of current devices and to develop new detection devices, comprehensive diagnostic procedures, and protocols. One such technology that is gaining popular attention over the recent years is the usage of electrical characteristics of the breast tissue to differentiate normal and cancerous tissues. Most of the devices using this technology are currently being used as adjunct diagnostic tools to improve the detection accuracy of established techniques like mammography and ultrasound. Also, early detection of breast cancer can help save many thousands of lives every year and can also reduce unnecessary healthcare expenditure caused by advanced stage treatment options. Hence, more research is also being done to adapt these devices into screening tools for early detection of breast cancer. The main objective of this review is to highlight the features of the currently available commercial devices that use this technology for breast cancer detection. The electrical behavior of normal and cancerous breast tissues is first presented. The various commercial devices that utilize electrical impedance or electropotentials for breast cancer detection are then described. Finally, conclusions and potential areas of research are highlighted.
authors.affiliation: Office of Biomedical Research, National University Hospital, Singapore. mykng@ntu.edu.sg
authors.forename: E Y K
authors.initials: EY
authors.lastname: Ng
authors.forename: S Vinitha
authors.initials: SV
authors.lastname: Sree
authors.forename: K H
authors.initials: KH
authors.lastname: Ng
authors.forename: G
authors.initials: G
authors.lastname: Kaw
mesh_terms: D001940:Breast / Q000503:physiopathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000503:physiopathology*; D002986:Clinical Trials as Topic; D017097:Electric Impedance; D004558:Electric Stimulation / Q000379:methods*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008280:Magnetics; D008327:Mammography / Q000379:methods; D008495:Medical Oncology / Q000379:methods; D015203:Reproducibility of Results; D012984:Software; D014054:Tomography / Q000379:methods; D016896:Treatment Outcome