title: [Study on effect of demethoxycurcumin in Curcuma long on stability of curcumin].
abstract: OBJECTIVE
  To investigate effect of demethoxycurcumin on stability of curcumin.
  
  
  METHODS
  To add the demethoxycurcumin to pure curcumin, the change of curcumin was determined by HPLC and the dynamics of curcumin degradation was investigated.
  
  
  RESULTS
  The stability both obtained from alcohol and demethoxycurcumin improved the stabilization of curcumin, the demi-period of curcumin prolonged with the addition of demethoxycurcumin.
  
  
  CONCLUSIONS
  The commixture of curcumin and demethoxycurcumin are more stable than pure curcumin at the same conditions. Stability of curcumin is improved by demethoxycurcumin,it is crude stabilizing agent.
authors.affiliation: Tangshan Key Laboratory of New Drug Research, Pharmaceutical Department of North China Coal Medical College, Tangshan 063000, China. tsyxhg@163.com
authors.forename: Gang
authors.initials: G
authors.lastname: Han
authors.forename: Rui
authors.initials: R
authors.lastname: Bi
authors.forename: Quan
authors.initials: Q
authors.lastname: Le
authors.forename: Lin-Lin
authors.initials: LL
authors.lastname: Zhao
authors.forename: Yue
authors.initials: Y
authors.lastname: Dong
authors.forename: Qing-Hui
authors.initials: QH
authors.lastname: Lin
mesh_terms: D002851:Chromatography, High Pressure Liquid; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification* / Q000378:metabolism; D036381:Diarylheptanoids; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D010946:Plants, Medicinal / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D036381:Diarylheptanoids; D004365:Drugs, Chinese Herbal; D000431:Ethanol; D003474:Curcumin; C050229:demethoxycurcumin