title: Xenon ventilation CT with a dual-energy technique of dual-source CT: initial experience.
abstract: Institutional review board approval and written informed consent were obtained. Although xenon (Xe) ventilation CT has been introduced as a potential method with which to depict regional ventilation, quantification of Xe enhancement has been limited by the variability of lung attenuation caused by different lung volumes between scans. The purpose of this study was to assess the feasibility of Xe ventilation CT with a dual-energy technique. Dual-energy CT was performed in 12 subjects after Xe inhalation. With use of a dual-energy technique, the Xe component could be extracted without any influence from lung volume. Dynamic and static regional ventilation function can be displayed with an exact match to the thin-section CT image.
authors.affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Chae
authors.forename: Joon Beom
authors.initials: JB
authors.lastname: Seo
authors.forename: Hyun Woo
authors.initials: HW
authors.lastname: Goo
authors.forename: Namkug
authors.initials: N
authors.lastname: Kim
authors.forename: Koun-Sik
authors.initials: KS
authors.lastname: Song
authors.forename: Sang Do
authors.initials: SD
authors.lastname: Lee
authors.forename: Soo-Jong
authors.initials: SJ
authors.lastname: Hong
authors.forename: Bernhard
authors.initials: B
authors.lastname: Krauss
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D016014:Linear Models; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012123:Pulmonary Ventilation; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014978:Xenon
chemical_list: D014978:Xenon