title: Perioperative beta-blockers in noncardiac surgery: evolution of the evidence.
abstract: After studies in the 1990s suggested that beta-blockers offer substantial benefits when given before surgery, several national organizations endorsed the perioperative use of these drugs as a best practice in certain patients, However, subsequent research has cast doubt on whether it is appropriate to use these drugs as widely as suggested by those early studies.
authors.affiliation: Cleveland Clinic Lerner College of Medicine of Case Western University, Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. harteb@ccf.org
authors.forename: Brian
authors.initials: B
authors.lastname: Harte
authors.forename: Amir K
authors.initials: AK
authors.lastname: Jaffer
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D017202:Myocardial Ischemia / Q000517:prevention & control*; D019990:Perioperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists