title: A synthetic approach to the fusicoccane A-B ring fragment based on a Pauson-Khand cycloaddition/Norrish type 1 fragmentation.
abstract: A synthetic approach to the A-B ring system within the fusicoccane family of diterpenes is presented. Key steps in this approach are a diastereoselective Pauson-Khand reaction, a Norrish 1 photofragmentation, a Charette cyclopropanation, and a ring-closing metathesis process.
authors.affiliation: Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, BC, Canada, V6T 1Z1.gdake@chem.ubc.ca
authors.forename: Gregory R
authors.initials: GR
authors.lastname: Dake
authors.forename: Erik E
authors.initials: EE
authors.lastname: Fenster
authors.forename: Brian O
authors.initials: BO
authors.lastname: Patrick
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry; D004224:Diterpenes / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D010777:Photochemistry; D013237:Stereoisomerism
chemical_list: D003521:Cyclopropanes; D004224:Diterpenes; C533054:fusicoccane A; C533055:fusicoccane B; C030797:cyclopropane