Adult-to-embryo chemical signaling in the regulation of larval development in trochophore animals: cellular and molecular mechanisms.
The regulation of larval development by starved adults occurs in both freshwater snails, Helisoma trivolvis and marine polychaetes, Platynereis dumerilii. Serotonin (5-HT) links this environmental signal which is detected by larval apical sensory neurons to changes in larval development. A profile of the stage-dependent expression of 5-HT receptors and coupled G proteins is essential in this regulatory mechanism. The final effect on development depends on the modulation of the activity of the larval digestive system.
Voronezhskaya
Elena E
EE
Department of Comparative Physiology, Institute for Developmental Biology, Moscow, Russia. lena_vor@mail.ru
Glebov
K I
KI
Khabarova
Marina Yu
MY
Ponimaskin
E G
EG
Nezlin
L P
LP
D000818:Animals; D007814:Larva / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D008954:Models, Biological; D011077:Polychaeta / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D011985:Receptors, Serotonin / Q000378:metabolism; D015398:Signal Transduction; D012908:Snails / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*
D043562:Receptors, G-Protein-Coupled; D011985:Receptors, Serotonin