Recurrent pulmonary cryptococcosis in a patient with idiopathic CD4 lymphocytopenia.
A case of recurrent cryptococcosis with idiopathic CD4 lymphocytopenia is reported in this article. After an initial cryptococcal infection in the lung, the patient experienced one episode of cryptococcal meningitis and two more episodes of cryptococcal pneumonia within a period of 12 years. Genetic studies revealed that all isolated microbes were identical, indicating that all subsequent episodes were recurrence instead of re-infection.
Yuanjie
Zhu
Z
Cryptococcus Lab, Department of Dermatology, Changzheng Hospital, Shanghai, China.
Julin
Gu
G
Fubing
Che
C
Jianghan
Chen
C
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D015496:CD4-Positive T-Lymphocytes / Q000473:pathology*; D002681:China; D003453:Cryptococcosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D008231:Lymphopenia / Q000209:etiology*; D012008:Recurrence; D016896:Treatment Outcome
D000935:Antifungal Agents