Epoxydons and a pyrone from the marine-derived fungus Nigrospora sp. PSU-F5.
Nigrospoxydons A-C (1- 3) and nigrosporapyrone (4), four new metabolites, were isolated from the marine-derived fungus Nigrospora sp. PSU-F5 together with nine known compounds. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopic techniques. The antibacterial activity against the standard Staphylococcus aureus ATCC 25923 and methicillin-resistant S. aureus was evaluated.
Trisuwan
Kongkiat
K
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.
Rukachaisirikul
Vatcharin
V
Sukpondma
Yaowapa
Y
Preedanon
Sita
S
Phongpaichit
Souwalak
S
Rungjindamai
Nattawut
N
Sakayaroj
Jariya
J
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification; D001203:Ascomycota / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D001688:Biological Products; D011753:Pyrones