Group efficiency: a guideline for hits-to-leads chemistry.
Verdonk
Marcel L
ML
Astex Therapeutics Ltd., 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK. m.verdonk@astex-therapeutics.com
Rees
David C
DC
D002626:Chemistry, Pharmaceutical; D004353:Drug Evaluation, Preclinical; D017408:Guidelines as Topic; D013816:Thermodynamics