Two new holostan-type triterpene glycosides from the sea cucumber Bohadschia marmorata JAEGER.
Two new holostan-type triterpene glycosides, 17-hydroxy fuscocineroside B (1) and 25-hydroxy fuscocineroside B (2), together with a known triterpene glycoside, fuscocineroside B (3) were isolated from the sea cucumber Bohadschia marmorata JAEGER. The structures of the new triterpene glycosides were elucidated on the basis of spectroscopic analyses and chemical reactions. Compounds 1 and 3 showed considerable antifungal activities against six strains.
Yuan
Weihua
W
Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai, PR China.
Yi
Yanghua
Y
Tang
Haifeng
H
Xue
Mei
M
Wang
Zenglei
Z
Sun
Guoquan
G
Zhang
Wen
W
Liu
Baoshu
B
Li
Ling
L
Sun
Peng
P
D000818:Animals; D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D012616:Sea Cucumbers / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000935:Antifungal Agents; D006027:Glycosides; D014315:Triterpenes; C515361:fuscocineroside B