title: Novel and efficient one-pot tandem synthesis of 2-styryl-substituted 4(3H)-quinazolinones.
abstract: A novel one-pot tandem synthesis of 2-styryl-4(3 H)-quinazolinones in an acidic ionic liquid is reported. In this procedure isatoic anhydride, a primary aniline or ammonium acetate, and triethylorthoacetate are reacted in the presence of imidazolium trifluoroacetate [Hmim]TFA. Subsequently an aromatic aldehyde is added to the mixture to afford the title compounds in high to excellent yields.
authors.affiliation: Department of Chemistry, Faculty of Science, Shahid Beheshti University, Postal Code 1983963113, Evin, Tehran, Iran. m-dabiri@sbu.ac.ir
authors.forename: Minoo
authors.initials: M
authors.lastname: Dabiri
authors.forename: Mostafa
authors.initials: M
authors.lastname: Baghbanzadeh
authors.forename: Akram Sadat
authors.initials: AS
authors.lastname: Delbari
mesh_terms: D000085:Acetates / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D008956:Models, Chemical; D010078:Oxazines / Q000737:chemistry; D052999:Quinazolinones / Q000138:chemical synthesis*; D014269:Trifluoroacetic Acid / Q000737:chemistry
chemical_list: D000085:Acetates; D000447:Aldehydes; D000814:Aniline Compounds; D007093:Imidazoles; D052578:Ionic Liquids; D010078:Oxazines; D052999:Quinazolinones; D014269:Trifluoroacetic Acid; C037902:isatoic anhydride; C023650:aniline