Dynamic changes in serum estradiol and progesterone levels in patients of premenstrual syndrome with adverse flow of liver-qi.
OBJECTIVE
To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome (PMS) and reveal partial microcosmic mechanisms of adverse flow of liver-qi.


METHODS
Estradiol (E2) and progesterone (P) levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.


RESULTS
In the group of PMS with adverse flow of liver-qi, the secretive peak value of E2 and P at the follicular phase significantly decreased, and the secretive peak value at the luteal phase did not come into being.


CONCLUSIONS
Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi. One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2 and P.
Qiao
Mingqi
M
College of Basic Medical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, China.
Zhang
Huiyun
H
Yu
Yanhong
Y
Ci
Yuzhen
Y
Xu
Xujie
X
Ye
Qing
Q
Chen
Yuzhen
Y
D000328:Adult; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D011293:Premenstrual Syndrome / Q000097:blood* / Q000473:pathology / Q000503:physiopathology; D011374:Progesterone / Q000097:blood*; D019413:Qi; D055815:Young Adult
D011374:Progesterone; D004958:Estradiol