Asymmetric synthesis of 4- and 5-substituted pipecolic esters by ring-closing metathesis and palladium-catalyzed formate reduction.
Asymmetric synthesis of 4- and 5-substituted pipecolic esters was achieved by the sequence of allylation, ring-closing metathesis, and palladium-catalyzed formate reduction.
Sun
Chong-Si
CS
Department of Chemistry, National Central University, 300 Jhong-Da Rd. Jhong-Li, Taoyuan, Taiwan.
Lin
Yu-Shiang
YS
Hou
Duen-Ren
DR
D000498:Allyl Compounds / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D004952:Esters / Q000138:chemical synthesis*; D005561:Formates / Q000737:chemistry*; D008956:Models, Chemical; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D010875:Pipecolic Acids / Q000138:chemical synthesis*
D000498:Allyl Compounds; D004952:Esters; D005561:Formates; D010875:Pipecolic Acids; D010165:Palladium