[Effects of delayed cord clamping on hemoglobin and ferritin levels in infants at three months of age].
This study assessed the effect of delayed (1 minute after delivery) clamping of the umbilical cord on hemoglobin and ferritin levels in infants at three months of age. Mothers and their infants born through vaginal delivery, at term, and without congenital anomalies (325 pairs) were recruited at a hospital in São Paulo, Brazil, in 2006 (164 in the delayed clamping subgroup and 161 in the early clamping subgroup). Maternal hemoglobin at delivery, umbilical cord hemoglobin, and ferritin were recorded. At three months follow-up, venous blood samples were drawn from 224 (69%) infants for hemoglobin and ferritin measurement. Socioeconomic, maternal reproductive, anthropometric, and infant feeding variables were studied. Multiple linear regression models were used to analyze the data. The effect of delayed clamping at birth, measured at three months, was only significant for ferritin (p = 0.040), and the concentration was higher (23.29ng/mL) in this subgroup as compared to the early clamping subgroup. Delayed umbilical cord clamping can serve as a strategy to improve infant iron status and prevent iron deficiency.
Venâncio
Sonia Isoyama
SI
Instituto de Saúde, Secretaria de Estado da Saúde de São Paulo, São Paulo, Brasil. soniav@isaude.sp.gov.br
Levy
Renata Bertazzi
RB
Saldiva
Sílvia Regina Dias Médici
SR
Mondini
Lenise
L
Alves
Maria Cecília Goi Porto
MC
Leung
Siu Lum
SL
D000740:Anemia / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D018798:Anemia, Iron-Deficiency / Q000517:prevention & control; D001938:Brazil / Q000453:epidemiology; D003250:Constriction; D005293:Ferritins / Q000097:blood*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007223:Infant; D009321:Natural Childbirth; D012959:Socioeconomic Factors; D013997:Time Factors; D014470:Umbilical Cord / Q000737:chemistry
D006454:Hemoglobins; D005293:Ferritins