Age-related chances of mitochondrial cytochrome C oxidase and F0F1-ATP synthase subunit contents in rat cerebral cortex.
The levels of subunits I, II/III, and IV of cytochrome c oxidase and of subunits alpha, beta and gamma of F(0)F(1)-ATP synthase in inner mitochondrial membrane proteins purified from cerebral cortex of rat at 2, 6, 12, 18, 24, 26 months of age were analyzed by Western blot. Age-related changes in the content of subunits, encoded either in mitochondrial or nuclear DNA, were observed.
Nicoletti
V G
VG
Institute of Biochemistry, Faculty of Medicine, University of Catania, Viale A. Doria 6, I-95125 Catania, Italy.
Tendi
E A
EA
Lalicata
C
C
Reale
S
S
Villa
R F
RF
Ragusa
N
N
Giuffrida-Stella
A M
AM