title: A case of sebaceoma with extensive apocrine differentiation.
abstract: Apocrine differentiation is a rare event in sebaceoma, and only 3 cases have been reported. We report a case of sebaceoma with extensive apocrine differentiation on the scalp in a 73-year-old Japanese woman. The resected tumor was located entirely within the dermis and subcutis as a well-circumscribed, lobulated, solid, and partially cystic mass, measuring 35 mm at the largest diameter. Histopathologically, it was composed of uniform basaloid cells with clusters of sebocytes, squamous islands of ductal structures, and apocrine cells with apparent decapitation secretion. Nuclear atypia of all types of cells was inconspicuous, and mitotic figures were infrequent. We considered the lesion to be a sebaceoma with apocrine differentiation.
authors.affiliation: Department of Pathology, Faculty of Medicine, Oita University, Yufu-shi, Oita, Japan. d04d4004@med.oita-u.ac.jp
authors.forename: Jin
authors.initials: J
authors.lastname: Tanahashi
authors.forename: Kenji
authors.initials: K
authors.lastname: Kashima
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Daa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kondoh
authors.forename: Naomi
authors.initials: N
authors.lastname: Yada
authors.forename: Eiji
authors.initials: E
authors.lastname: Kuratomi
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yokoyama
mesh_terms: D006607:Adenoma, Sweat Gland / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D000368:Aged; D001050:Apocrine Glands / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012535:Scalp / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000378:metabolism / Q000473:pathology*