title: Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study.
abstract: Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population.
  
  
  OBJECTIVE
  to study the impact of amoxicillin for 7 days in post-adenotonsillectomy recovery, comparing results with a control group.
  
  
  METHODS
  prospective, randomized, controlled study with 120 patients.
  
  
  METHODS
  the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities.
  
  
  RESULTS
  It was only in the fourth post-operative day that the group receiving antibiotic agents showed a statistically significant difference as far as pain is concerned. There was no difference between the two groups for other data analyzed.
  
  
  CONCLUSIONS
  considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.
authors.affiliation: FMABC, Brazil.
authors.forename: Marja Michelin
authors.initials: MM
authors.lastname: Guerra
authors.forename: Eduardo
authors.initials: E
authors.lastname: Garcia
authors.forename: Renata Ribeiro de Mendonça
authors.initials: RR
authors.lastname: Pilan
authors.forename: Priscila Bogar
authors.initials: PB
authors.lastname: Rapoport
authors.forename: Caio Barbosa
authors.initials: CB
authors.lastname: Campanholo
authors.forename: Eli Onivaldo
authors.initials: EO
authors.lastname: Martinelli
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000658:Amoxicillin / Q000009:adverse effects / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D004177:Dipyrone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005334:Fever / Q000517:prevention & control; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D014068:Tonsillectomy
chemical_list: D018712:Analgesics, Non-Narcotic; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen; D004177:Dipyrone; D000658:Amoxicillin