title: Acute disseminated encephalomyelitis: clinical and pathogenesis features.
abstract: Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADEM reveals involvement of white matter, with infiltration of monocytoid cells and perivenous demyelination.
authors.affiliation: Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.
authors.forename: Farshid
authors.initials: F
authors.lastname: Noorbakhsh
authors.forename: Richard T
authors.initials: RT
authors.lastname: Johnson
authors.forename: Derek
authors.initials: D
authors.lastname: Emery
authors.forename: Christopher
authors.initials: C
authors.lastname: Power
mesh_terms: D003937:Diagnosis, Differential; D004673:Encephalomyelitis, Acute Disseminated / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D006801:Humans; D007114:Immunization; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D014765:Viral Vaccines / Q000008:administration & dosage
chemical_list: D014765:Viral Vaccines