title: (2+2) cycloaddition reaction of alkyl enol ethers with acrylates by in situ generated silyl triflic imide catalyst.
abstract: We describe here (2+2) cycloaddition reaction of alkyl enol ethers with acrylates catalyzed by triethylsilyl triflic imide (Et3SiNTf2), which was in situ generated from triethylsilane and triflic imide. The reaction efficiently provides substituted cyclobutanes bearing alkoxy function in a stereoselective manner.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. kay-t@pharm.kyoto-u.ac.jp
authors.forename: Kiyosei
authors.initials: K
authors.lastname: Takasu
authors.forename: Yuta
authors.initials: Y
authors.lastname: Miyakawa
authors.forename: Masataka
authors.initials: M
authors.lastname: Ihara
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Tokuyama
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D002384:Catalysis; D004986:Ether / Q000737:chemistry; D004987:Ethers / Q000737:chemistry*; D007094:Imides / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D012821:Silanes / Q000737:chemistry
chemical_list: D000179:Acrylates; D004987:Ethers; D007094:Imides; D007659:Ketones; D012821:Silanes; D004986:Ether; C512918:triethylsilane