title: Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India.
abstract: To determine the incidence and natural history of congenital cytomegalovirus (CMV) infection in a population of women with near universal serologic reactivity for CMV, a prospective study of 423 women attending the antenatal clinic of the Comprehensive Rural Health Center in northern India was conducted. All 9 (2.1%) CMV positive infants were born to mothers who were CMV seropositive at the first antenatal visit. One child had hepatosplenomegaly at birth and another child had mild unilateral hearing loss at 4 months of age.
authors.affiliation: Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Lalit
authors.initials: L
authors.lastname: Dar
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Pati
authors.forename: A Raj Kumar
authors.initials: AR
authors.lastname: Patro
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Deorari
authors.forename: Sanjay
authors.initials: S
authors.lastname: Rai
authors.forename: Shashi
authors.initials: S
authors.lastname: Kant
authors.forename: Shobha
authors.initials: S
authors.lastname: Broor
authors.forename: Karen B
authors.initials: KB
authors.lastname: Fowler
authors.forename: William J
authors.initials: WJ
authors.lastname: Britt
authors.forename: Suresh B
authors.initials: SB
authors.lastname: Boppana
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000453:epidemiology*; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D015994:Incidence; D007194:India / Q000453:epidemiology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology* / Q000821:virology*; D009035:Mothers; D011446:Prospective Studies; D012424:Rural Population; D013163:Splenomegaly / Q000209:etiology; D014556:Urine / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M