[Phosphoproteomics and its application in cancer research].
Phosphoproteome is the whole complement of phosphorylated proteins in a cell, tissue or organism, and has become an interesting study subject since the discovery of phosphorylation as a key regulatory mechanism of cell life. Phosphoproteomics is a method which studies the compact of the phosphorylated proteins, expression and modification, interaction and association, rule of the regulatory and so on. Recently, phosphoproteomics is widely used in cancer research. It will provide important information in cancer research, cancer diagnosis, and therapy.
Liu
Jie-Qiong
JQ
Cancer Research Institute, Central South University, Changsha 410078, China.
He
Zhi-Min
ZM
D066246:ErbB Receptors / Q000235:genetics; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism*; D010750:Phosphoproteins / Q000235:genetics / Q000378:metabolism*; D010766:Phosphorylation; D040901:Proteomics / Q000379:methods; D015398:Signal Transduction
D010750:Phosphoproteins; D066246:ErbB Receptors