Impact of diversity of colonizing strains on strategies for sampling Escherichia coli from fecal specimens.
Of 49 subjects, 21 were colonized with more than one strain of Escherichia coli and 12 subjects had at least one strain present in fewer than 20% of colonies. The ability to accurately characterize E. coli strain diversity is directly related to the number of colonies sampled and the underlying prevalence of the strain.
Lautenbach
Ebbing
E
Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6021, USA. ebbing@mail.med.upenn.edu
Bilker
Warren B
WB
Tolomeo
Pam
P
Maslow
Joel N
JN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000235:genetics* / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology*; D005260:Female; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged