Molecular epidemiology of dengue virus type 3 in Northern South America: 2000--2005.
A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.
Kochel
Tadeusz
T
United States Naval Medical Research Center Detachment, Unit 3800, APO AA 34031, American Embassy, Lima, Peru. tad.kochel@med.navy.mil
Aguilar
Patricia
P
Felices
Vidal
V
Comach
Guillermo
G
Cruz
Cristopher
C
Alava
Aracely
A
Vargas
Jorge
J
Olson
James
J
Blair
Patrick
P
D036022:Capsid Proteins / Q000235:genetics; D003715:Dengue / Q000453:epidemiology* / Q000821:virology*; D003716:Dengue Virus / Q000145:classification / Q000235:genetics*; D019143:Evolution, Molecular; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D010802:Phylogeny; D013020:South America / Q000453:epidemiology; D014759:Viral Envelope Proteins / Q000235:genetics; D014764:Viral Proteins / Q000235:genetics
D036022:Capsid Proteins; C084188:E protein, Dengue virus type 3; D014759:Viral Envelope Proteins; D014764:Viral Proteins; C084187:prM protein, Dengue virus type 3