Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India.
To determine the incidence and natural history of congenital cytomegalovirus (CMV) infection in a population of women with near universal serologic reactivity for CMV, a prospective study of 423 women attending the antenatal clinic of the Comprehensive Rural Health Center in northern India was conducted. All 9 (2.1%) CMV positive infants were born to mothers who were CMV seropositive at the first antenatal visit. One child had hepatosplenomegaly at birth and another child had mild unilateral hearing loss at 4 months of age.
Dar
Lalit
L
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Pati
Sunil Kumar
SK
Patro
A Raj Kumar
AR
Deorari
Ashok Kumar
AK
Rai
Sanjay
S
Kant
Shashi
S
Broor
Shobha
S
Fowler
Karen B
KB
Britt
William J
WJ
Boppana
Suresh B
SB
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000453:epidemiology*; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D015994:Incidence; D007194:India / Q000453:epidemiology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology* / Q000821:virology*; D009035:Mothers; D011446:Prospective Studies; D012424:Rural Population; D013163:Splenomegaly / Q000209:etiology; D014556:Urine / Q000821:virology
D000914:Antibodies, Viral; D007075:Immunoglobulin M