title: The safety and efficacy of bilateral simultaneous total hip replacement: an analysis of 2063 cases.
abstract: Comparison of the safety and efficacy of bilateral simultaneous total hip replacement (THR) and that of staged bilateral THR and unilateral THR was conducted using DerSimonian-Laird heterogeneity meta-analysis. A review of the English-language literature identified 23 citations eligible for inclusion. A total of 2063 bilateral simultaneous THR patients were identified. Meta-analysis of homogeneous data revealed no statistically significant differences in the rates of thromboembolic events (p = 0.268 and p = 0.365) and dislocation (p = 0.877) when comparing staged or unilateral with bilateral simultaneous THR procedures. A systematic analysis of heterogeneous data demonstrated that the mean length of hospital stay was shorter after bilateral simultaneous THR. Higher blood transfusion requirements were expected following bilateral simultaneous THR than staged or unilateral THR, and surgical time was not different between groups. This procedure was also found to be economically and functionally efficacious when performed by experienced surgeons in specialist centres.
authors.affiliation: Academic Department of Trauma and Orthopaedics, Leeds General Infirmary, Leeds School of Medicine, Leeds University, Great George Street, Leeds LS1 3EX, UK. etsiridis@doctors.org.uk
authors.forename: E
authors.initials: E
authors.lastname: Tsiridis
authors.forename: G
authors.initials: G
authors.lastname: Pavlou
authors.forename: J
authors.initials: J
authors.lastname: Charity
authors.forename: Ev
authors.initials: E
authors.lastname: Tsiridis
authors.forename: G
authors.initials: G
authors.lastname: Gie
authors.forename: R
authors.initials: R
authors.lastname: West
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods* / Q000592:standards; D006801:Humans; D007902:Length of Stay; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality; D011655:Pulmonary Embolism / Q000209:etiology* / Q000401:mortality; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D013223:Statistics as Topic; D020246:Venous Thrombosis / Q000209:etiology* / Q000401:mortality