title: SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles.
abstract: SCK nanoparticles having differing core thermal characteristics were designed and evaluated as thermoresponsive drug delivery systems of doxorubicin for the killing of cancerous cells.
authors.affiliation: Center for Materials Innovation, Department of Chemistry and Department of Radiology, Washington University in Saint Louis, Saint Louis, Missouri 63130-4899, USA.
authors.forename: Andreas M
authors.initials: AM
authors.lastname: Nyström
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Xu
authors.forename: Jinqi
authors.initials: J
authors.lastname: Xu
authors.forename: Sara
authors.initials: S
authors.lastname: Taylor
authors.forename: Thalia
authors.initials: T
authors.lastname: Nittis
authors.forename: Sheila A
authors.initials: SA
authors.lastname: Stewart
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Leonard
authors.forename: Karen L
authors.initials: KL
authors.lastname: Wooley
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D004317:Doxorubicin / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D053758:Nanoparticles / Q000737:chemistry*; D013696:Temperature
chemical_list: D000970:Antineoplastic Agents; D004337:Drug Carriers; D004317:Doxorubicin