Regulation of the intercellular adhesin locus regulator (icaR) by SarA, sigmaB, and IcaR in Staphylococcus aureus.
The staphylococcal accessory regulator SarA and the alternative sigma factor sigma(B) have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and sigma(B) are also required for icaR expression and that IcaR does not have a significant effect on its own expression.
Cerca
Nuno
N
Department of Microbiology and Immunology, Virginia Commonwealth University, P.O. Box 980678, Richmond, VA 23928, USA.
Brooks
Jamie L
JL
Jefferson
Kimberly K
KK
D018829:Adhesins, Bacterial / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D018441:Biofilms / Q000254:growth & development; D015964:Gene Expression Regulation, Bacterial; D005816:Genetic Complementation Test; D008954:Models, Biological; D009154:Mutation; D011401:Promoter Regions, Genetic / Q000235:genetics; D012808:Sigma Factor / Q000235:genetics / Q000378:metabolism; D013211:Staphylococcus aureus / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism
D018829:Adhesins, Bacterial; D001426:Bacterial Proteins; C088021:SarA protein, bacterial; D012808:Sigma Factor; D015534:Trans-Activators