Combined right nephrectomy and pancreaticoduodenectomy. Indications and outcomes.
BACKGROUND
Nephrectomy and pancreaticoduodenctomy are operations often performed for the treatment of malignancy. However, the combination of both procedures is rarely reported.


OBJECTIVE
The indications and outcomes of combined right nephrectomy and pancreaticoduodenectomy were assessed.


METHODS
Patients were identified from a prospective operative database between 2002 and 2008.


METHODS
A tertiary care center.


METHODS
One-hundred and 80 patients undergoing pancreaticoduodenectomy. There were 5 (2.8%) patients treated by combined right nephrectomy and pancreaticoduodenal resection.


METHODS
Description of these 5 patients.


RESULTS
Three patients had retroperitoneal sarcomas adherent to the right kidney and duodenum, one patient had a locally advanced transitional-cell carcinoma and the remaining patient presented with an ampullary malignancy and concurrent right renal tumor All patients underwent en bloc resection with clear margins. Median operating time was 13 hours (range: 9-21 hours). There was no perioperative mortality in this series. Complications were noted in 3 (60%) patients related to pancreaticoduodenal resection and all were managed conservatively without significant clinical impact. Median post-operative hospital stay was 8 days (range: 7-11 days). At a median follow-up of 14 months (range: 3-36 months) all patients were alive without evidence of disease recurrence.


CONCLUSIONS
En bloc right nephrectomy combined with pancreaticoduodenal resection can be performed in selected patients with malignant tumors with acceptable morbidity to achieve clear resection margins.
Nikfarjam
Mehrdad
M
Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine. Hershey, PA 17033-0850, USA.
Gusani
Niraj J
NJ
Kimchi
Eric T
ET
Mahraj
Rickhesvar P
RP
Staveley-O'Carroll
Kevin F
KF
D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects / Q000706:statistics & numerical data*; D017063:Outcome Assessment, Health Care; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000706:statistics & numerical data*; D018579:Patient Selection; D010414:Pennsylvania; D011446:Prospective Studies; D012186:Retroperitoneal Neoplasms / Q000601:surgery*; D013997:Time Factors