title: [Clinical observation on catgut implantation at Shu- and Mu-acupoints for treatment of premature ovarian failure].
abstract: OBJECTIVE
  To observe clinical therapeutic effect of catgut implantation at Shu- and Mu-acupoints of liver, spleen and kidney on premature ovarian failure.
  
  
  METHODS
  One hundred and thirty-two cases of premature ovarian failure were randomly divided into a catgut implantation group and a medication group, 66 cases in each group. The catgut implantation group were treated by catgut implantation at She- and Mu-acupoints of liver, spleen and kidney, and the medication group were treated with oral administration of Estradiol Valerate 2 mg, qd, for 20 days, and 10 days later, Medroxyprogesterone Acetate 4 mg was added, b. i. d, for 10 days, averaging 6 months of medication. The therapeutic effects and changes of serum follicle-stimulating hormone (FSH) and estradiol (E2) were observed in the two groups.
  
  
  RESULTS
  After treatment, serum FSH and E2 significantly improved in the two groups (P<0.01), with the serum E2 in the catgut implantation group increased more significantly than that in the medication group (P<0.01). The cured rate and the total effective rate were 84.9% and 97.0% in the catgut implantation group and 31.8% and 84.8% in the medication group, the cured rate in the catgut implantation group being better than that in the medication group (P<0.05). Ten month later, the therapeutic effect in the catgut implantation group was kept.
  
  
  CONCLUSIONS
  Catgut implantation at Shu- and Me-acupoints of liver, spleen and kidney has a good therapeutic effect on premature ovarian failure with no side effect.
authors.affiliation: First Clinical Medical College, Guangzhou University of TCM, Guangdong 510405, China. hongjiao1029@163.com
authors.forename: Hong-Jiao
authors.initials: HJ
authors.lastname: Liu
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Peng
authors.forename: Xue-Bing
authors.initials: XB
authors.lastname: Xu
mesh_terms: D015669:Acupuncture Points; D000328:Adult; D002398:Catgut; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D016649:Primary Ovarian Insufficiency / Q000628:therapy*
chemical_list: D004958:Estradiol; D005640:Follicle Stimulating Hormone