title: Sesquiterpenes from Curcuma comosa.
abstract: From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7 alpha-hydroxyneocurdione, 7 beta-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Qu
authors.forename: Fengming
authors.initials: F
authors.lastname: Xu
authors.forename: Seikou
authors.initials: S
authors.lastname: Nakamura
authors.forename: Hisashi
authors.initials: H
authors.lastname: Matsuda
authors.forename: Yutana
authors.initials: Y
authors.lastname: Pongpiriyadacha
authors.forename: Lijun
authors.initials: L
authors.lastname: Wu
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshikawa
mesh_terms: D030024:Curcuma / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D045788:Sesquiterpenes, Germacrane / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D005663:Furans; D006574:Heterocyclic Compounds, 2-Ring; D010936:Plant Extracts; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; C504126:curdione; C117943:dehydrocurdione; C442489:furanodiene; C438916:procurcumenol; C048393:germacrone; C053720:alismol