Genetic diversity of Porphyromonas gingivalis isolates recovered from single "refractory" periodontitis sites.
Multilocus sequence typing and fimA genotyping were performed on Porphyromonas gingivalis isolates from 15 subjects with "refractory" periodontitis. Several sequence types were detected for most individual pockets. The variation indicated recombination at the recA and pepO genes. The prevalence of fimA genotypes II and IV confirmed their association with periodontitis.
Enersen
Morten
M
Institute of Oral Biology, Faculty of Dentistry, University of Oslo, P.O. Box 1052, NO-0316 Oslo, Norway. morteene@odont.uio.no
Olsen
Ingar
I
Caugant
Dominique A
DA
D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000235:genetics; D010450:Endopeptidases / Q000235:genetics; D036781:Fimbriae Proteins / Q000235:genetics; D005798:Genes, Bacterial; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D010514:Periodontal Pocket / Q000382:microbiology; D010518:Periodontitis / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D011938:Rec A Recombinases / Q000235:genetics
D001426:Bacterial Proteins; D004269:DNA, Bacterial; C063055:fimbrillin; D036781:Fimbriae Proteins; D011938:Rec A Recombinases; D010450:Endopeptidases