[Association between refractory hypertension and cardiometabolic risk. The HIPERFRE study].
OBJECTIVE
Resistant hypertension (R-HT) is defined by the presence of uncontrolled blood pressure in patients treated with three or more drugs, being one of them diuretic. We sough to evaluate the prevalence and features of patients with R-HT attended at Primary Care of our environment.


METHODS
1724 hypertensive patients attended by 35 physicians at 14 Primary Care Units were analyzed in this descriptive, transversal, multicentral study.


RESULTS
Patients (41.5% males) with a mean age of 67+/-11 years, being half of them obese. Blood pressure is controlled in 41.6% and the prevalence of R-HT is of 13.2%. This later group of patients is characterized by an older age (69 vs 67 years, p<0.01) and more frequent obesity (62% vs 43%, p<0.001), diabetes (55% vs 11%, p<0.001), hyperlipidemia (68% vs 59%, p<0.05), and metabolic syndrome (68% vs 22%, p<0.001). At least half of them present some kind of end-organ damage. No pharmacologycal treatment is prescribed to 3% of these patients and 37% of them are on monotherapy. There is a higher prescription of angiotensin receptor, calcium channel, beta and alfa-blockers in the group of patients with R-HT. There is an independent and direct relationship between R-HT and age, male gender, diabetes, obesity, metabolic syndrome, and an inverse relationship with ischemic cardiopathy.


CONCLUSIONS
The prevalence of R-HT at Primary Care Units is of 13% and is related with age, male gender and metabolic risk factors.
Otero
F Raviña
FR
Servicio Galego de Saúde, Santiago de Compostela, Coruña, España. fernando.otero.ravina@serga.es
Grigorian
L Shamagian
LS
Lado
M López
ML
Lado
A Llerena
AL
Turrado
V Turrado
VT
Santos
J A Rodríquez
JA
Pazo
C Paniagua
CP
Vázquez
J A Mallo
JA
Vaamonde
L Mosquera
LM
González
J R Juanatey
JR
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008659:Metabolic Diseases / Q000209:etiology*; D008875:Middle Aged; D012307:Risk Factors