Solid variant of primary effusion lymphoma in successfully treated HIV infection: a case report.
Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, mainly met in severely immunocompromised, HIV-positive patients. PEL is aetiologically related to human herpes virus-8 (HHV-8) and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumour mass. Recently, cases of HIV-positive patients with HHV-8-positive solid tissue lymphomas, not associated with an effusion, have been reported (solid variant of PEL). The prognosis of PEL is reported to be poor. We report a case of an HIV-positive patient with a typical solid variant of PEL without effusion. Interestingly, his disease developed while being on stable antiretroviral therapy (ART) with high CD4 counts. He had a relatively long survival with chemotherapy and ART.
Mylona
E
E
Fifth Department of Internal Medicine, Evaggelismos Hospital, Athens, Greece. emylon@med.uoa.gr
Baraboutis
I G
IG
Georgiou
O
O
Rondogianni
D
D
Lekakis
L J
LJ
Papastamopoulos
V
V
Apostolidis
I
I
Skoutelis
A T
AT
D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D015497:HIV-1 / Q000187:drug effects; D019288:Herpesvirus 8, Human; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000473:pathology* / Q000821:virology; D054685:Lymphoma, Primary Effusion / Q000473:pathology* / Q000821:virology; D008297:Male; D016896:Treatment Outcome
D019380:Anti-HIV Agents