title: CFD analysis of a Mag-Lev ventricular assist device for infants and children: fourth generation design.
abstract: Thousands of pediatric patients suffering from heart failure would benefit from longer-term mechanical circulatory support. There are, however, few support systems available in the United States as viable mechanical assist alternatives for these patients. Therefore, we have designed and developed an axial flow pediatric ventricular assist device (PVAD) with an impeller that is fully suspended by magnetic bearings. This blood pump is designed to generate 0.5-4 L/min for pressure rises of 50-95 mm Hg over 6,000-9,000 rpm. We have performed four major design iterations. Building upon the third design phase, we made improvements to create the PVAD4 model. Numerical simulations of the PVAD4 under steady flow simulations were performed to compare the predictions of the latest PVAD4 model to the earlier PVAD3 design. The PVAD4 design resulted in lower fluid stress levels and an increase in pressure generation. A blood damage analysis was also completed. As compared with the earlier PVAD3 design, the damage analysis of the PVAD4 indicated a reduction in the mean and maximum damage index for the new design. All of these numerical findings are encouraging and demonstrate progress toward achieving a superior pump design.
authors.affiliation: Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, Virginia 23284-3015, USA. althrock@vcu.edu
authors.forename: Amy L
authors.initials: AL
authors.lastname: Throckmorton
authors.forename: Alexandrina
authors.initials: A
authors.lastname: Untaroiu
mesh_terms: D002648:Child; D006353:Heart-Assist Devices; D018056:Hemorheology; D006801:Humans; D007223:Infant; D008955:Models, Cardiovascular; D011474:Prosthesis Design / Q000295:instrumentation*