[Effect of a personalized diet in the metabolic control and renal function of patients with type 2 diabetes].
OBJECTIVE
to evaluate a personalized diet customize for present comorbidity, on metabolic control indicators and renal function.


METHODS
a non-randomized clinical trial was conducted during a three-month period in a group of patients with microalbuminuria and in a group with macroalbuminuria. The patients received personalized dietary counseling customize to their comorbidity (obesity, hypertension, and dislypidemia). The effect of the diet was measured through metabolic control variables: body mass index (BMI), waist circumference, fasting glucose levels, glycated hemoglobin (HbA(1))c and lipids profile; the renal function variables were: glomerular filtration rate (GFR) and urine albumin excretion (UAE). Statistical analysis was done with t-paired test.


RESULTS
thirty-nine patients were included (21 women and 18 men). After the intervention, the weight and waist circumference had significantly decreased (p = 0.01); the fasting glucose levels and HbA(1)c were significantly lower (p = 0.001). The HDL-cholesterol increased significantly (p = 0.009); UAE decreased significantly in patients with micro and macroalbuminuria; 123.0 +/- 73.4 to 105.3 +/- 61.3 mg/24-h; p = 0.040 and 1482.7 +/- 1200.6 to 1093.5 +/- 601.8 mg/24-h; p = 0.02. The GFR increased in both groups: 68.9 +/- 35.4 to 74.7 +/- 41.6 mL/min, p = 0.04; and 62.2 +/- 26.6 to 68.5 +/- 25.3 mL/min, p = 0.02.


CONCLUSIONS
the dietary intervention improved the metabolic control and renal function in type 2 diabetes patients with comorbidity.
Velázquez-López
Lubia
L
Hospital Regional 1, Unidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social.
Sil-Acosta
María Juana
MJ
Goycochea-Robles
María Victoria
MV
Escobedo-De la Peña
Jorge
J
Castañeda-Limones
Rutila
R
D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000178:diet therapy* / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D003927:Diet, Diabetic; D002149:Energy Intake; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000178:diet therapy; D006973:Hypertension / Q000178:diet therapy; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy