title: Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia.
abstract: OBJECTIVE
  To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors.
  
  
  METHODS
  We examined associations among several domains of executive function (working memory, behavioral inhibition, cognitive flexibility, and self-monitoring), coping, and emotional/behavioral problems in 30 children and adolescents ages 10- to 20-years old who completed treatment for ALL and 30 healthy controls matched on age and sex.
  
  
  RESULTS
  We found partial support for our hypothesis that performance on executive function measures is associated with strategies used to cope with stress, and emotional and behavioral problems in ALL survivors.
  
  
  CONCLUSIONS
  Findings suggest that executive function impairment may be associated with difficulties in coping and emotion regulation in a subgroup of children treated for ALL. Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.
authors.affiliation: Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, P.O. Box 800223, Charlottesville, VA 22908-0223, USA. lkc3h@virginia.edu
authors.forename: Laura K
authors.initials: LK
authors.lastname: Campbell
authors.forename: Mary
authors.initials: M
authors.lastname: Scaduto
authors.forename: Deborah
authors.initials: D
authors.lastname: Van Slyke
authors.forename: Frances
authors.initials: F
authors.lastname: Niarhos
authors.forename: James A
authors.initials: JA
authors.lastname: Whitlock
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Compas
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D003071:Cognition; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000523:psychology*; D013315:Stress, Psychological / Q000209:etiology*; D017741:Survivors / Q000523:psychology*; D055815:Young Adult