title: Improvements in vision-related quality of life with AcrySof IQ SN60WF aspherical intraocular lenses.
abstract: OBJECTIVE
  To compare vision-related quality of life and higher-order aberrations (HOAs) with an aspherical intraocular lens (IOL) (AcrySof IQ SN60WF) and a conventional spherical IOL (AcrySof SA60AT) (both Alcon) after phacoemulsification.
  
  
  METHODS
  Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
  
  
  METHODS
  Sixty-five patients were prospectively randomized to receive an Alcon AcrySof IQ SN60WF IOL (30 eyes) or an AcrySof SA60AT IOL (35 eyes). All patients had a complete ophthalmologic examination including uncorrected visual acuity, best spectacle-corrected visual acuity (BSCVA), and wavefront analysis preoperatively and 3 months postoperatively. Patients also completed the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) to evaluate vision-related quality of life.
  
  
  RESULTS
  The mean postoperative BSCVA (logMAR) was 0.09 +/- 0.07 (SD) in the aspherical IOL group and 0.12 +/- 0.08 in the spherical IOL group; the difference was not statistically significant. Spherical aberrations were statistically significantly lower in the aspherical IOL group (mean 0.12 +/- 0.23 microm) than in the spherical IOL group (mean 0.33 +/- 0.20 microm) (P = .001). Both IOL types improved most aspects of patients' vision-related quality of life. The aspherical IOL group had clinically significant improvement on more NEI VFQ-25 subscales, although the difference between groups in vision-related quality of life was not statistically significant.
  
  
  CONCLUSIONS
  Eyes with the aspherical AcrySof IQ SN60WF IOL had reduced HOAs and spherical aberrations compared with eyes with the spherical AcrySof SA60AT IOL; however, there were no statistically significant differences in visual acuity or vision-related quality of life between groups.
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, ROC.
authors.forename: I-Chan
authors.initials: IC
authors.lastname: Lin
authors.forename: I-Jong
authors.initials: IJ
authors.lastname: Wang
authors.forename: Mei-Shu
authors.initials: MS
authors.lastname: Lei
authors.forename: Luke L-K
authors.initials: LL
authors.lastname: Lin
authors.forename: Fung-Rong
authors.initials: FR
authors.lastname: Hu
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014785:Vision, Ocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000180:Acrylic Resins