title: Umbilical cord ulceration after prenatal diagnosis of duodenal atresia with interstitial deletion of chromosome 13q: a case report.
abstract: Umbilical cord ulceration complicated by massive local hemorrhage may be a lethal event in the fetus, and this ulceration has been reported to be associated with upper intestinal atresia. The diagnosis of umbilical cord bleeding is difficult. We present a case of umbilical cord ulceration, hemorrhage, and duodenal atresia which had, in addition, an interstitial deletion of chromosome 13q. A female infant weighing 1,691 g was delivered by cesarean section at 34 weeks of gestation and had resuscitation and laparotomy. Just before the cesarean section, ultrasonography showed a 'double bubble' sign and a linear shadow, suggesting fibrin in the amniotic cavity. This finding may help in the diagnosis of bleeding from the cord.
authors.affiliation: Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, Japan. hidehiko@pluto.dti.ne.jp
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Miyake
authors.forename: Akihito
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamada
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okazaki
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Morita
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kondo
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ishida
authors.forename: Takako
authors.initials: T
authors.lastname: Nishina
authors.forename: Akishige
authors.initials: A
authors.lastname: Yokota
authors.forename: Akihito
authors.initials: A
authors.lastname: Nakai
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Takeshita
mesh_terms: D000328:Adult; D002585:Cesarean Section; D002872:Chromosome Deletion; D002882:Chromosomes, Human, Pair 13; D004380:Duodenal Obstruction / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology; D007621:Karyotyping; D011247:Pregnancy; D014057:Tomography, X-Ray Computed; D014456:Ulcer / Q000000981:diagnostic imaging / Q000209:etiology*; D016216:Ultrasonography, Prenatal; D014470:Umbilical Cord / Q000000981:diagnostic imaging*