title: Management of peripheral arterial disease patients: comparing the ACC/AHA and TASC-II guidelines.
abstract: BACKGROUND
  Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis associated with a high risk of morbidity and mortality from cardiovascular events. Despite this, PAD is often undiagnosed and, therefore, undertreated.
  
  
  OBJECTIVE
  The purpose of this review is to highlight and provide clinical insight into the similarities and differences between the available PAD treatment guidelines developed by the American College of Cardiology/American Heart Association (ACC/AHA) and the Trans-Atlantic Inter-Society Consensus II (TASC II) working group.
  
  
  METHODS
  Recommendations from the ACC/AHA 2005 Practice Guidelines for the Management of Patients with Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic) and TASC II Inter-Society Consensus for the Management of Peripheral Arterial users for personal Disease, initiated in 2004 and published in 2007, were compared. Supplemental information was obtained by searching the PubMed and MEDLINE databases using relevant terms. Unintentional bias may have been introduced into the manuscript by not performing a systematic review of the literature with pre-defined search terms.
  
  
  CONCLUSIONS
  While some variation exists in the content of the recommendations, both documents agree on the need for aggressive management of patients with PAD. In spite of these recommendations, there is a general lack of adherence to the current guidelines-a critical concern considering the high morbidity and mortality associated with the disease. However, the results of ongoing clinical trials may serve to increase awareness of the importance of aggressive management of PAD.
authors.affiliation: University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. mohlere@uphs.upenn.edu
authors.forename: Emile
authors.initials: E
authors.lastname: Mohler
authors.forename: Jay
authors.initials: J
authors.lastname: Giri
mesh_terms: D006801:Humans; D008019:Life Style; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D017410:Practice Guidelines as Topic; D016540:Smoking Cessation