[Studies on resistance mechanisms to paralytic shellfish poisoning in bivalves].
Paralytic shellfish poisoning (PSP) toxins could be neuromuscular paralysis agents, which could blocke the voltage-gated sodium channels, and then could cause holdback in nervous system transmission. Some bivalves could be tolerant of PSP toxins. The resistance mechanisms might be related to metabolism, biotransformation and the mutation of voltage-gated sodium channels, etc., in which the mutation of sodium channels might be the most important molecular mechanism of the resistance mechanism of bivalves.
Cui
Weimin
W
Department of Biotechnology, Jinan University, Guangzhou 510632, China.
Yang
Weidong
W
Liu
Jiesheng
J
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D049872:Bivalvia / Q000502:physiology*; D008387:Marine Toxins / Q000737:chemistry / Q000633:toxicity*; D057096:Shellfish Poisoning
D008387:Marine Toxins