title: [Thermosensitive polymers in drug form technology. II. Possibilities of use of thermosensitive polymers as active substance carriers].
abstract: Thermosensitive drug delivery can be used as substances carriers, which are applied in oral system, vaginal systems of release, applied on skin, the rectal, nasal, passed to eyes and parenteral. Sol-gel transition of the prepared formulations at physiological temperature ranges of the body makes possible their application in the liquid state and subsequent gelification in situ providing a prolonged release of the active substance at the application site.
authors.affiliation: Katedra i Zakład Technologii Postaci Leku Akademia Medyczna im. Piastów Slaskich, Wrocław. bozkar@wp.pl
authors.forename: Bozena
authors.initials: B
authors.lastname: Karolewicz
authors.forename: Janusz
authors.initials: J
authors.lastname: Pluta
mesh_terms: D000279:Administration, Cutaneous; D001704:Biopolymers / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D004333:Drug Administration Routes; D004337:Drug Carriers / Q000737:chemistry* / Q000145:classification*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D009883:Ophthalmic Solutions / Q000008:administration & dosage; D044367:Phase Transition; D011108:Polymers / Q000737:chemistry* / Q000145:classification*; D013148:Spironolactone / Q000737:chemistry; D013329:Structure-Activity Relationship; D013696:Temperature
chemical_list: D001704:Biopolymers; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D009883:Ophthalmic Solutions; D011108:Polymers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D013148:Spironolactone