title: Some O,O',O'',O'''-di/tetra aryldithioimidophonate transition metal complexes derived from catechol and bisphenol-A as antibacterial and antifungal agents.
abstract: Two new substituted-thioimidophonate derivatives H1L1 (O,O',O'',O'''-diaryldithioimidophonates) and H1L2 (O,O',O'',O'''-tetra aryldithioimidophonates) were synthesized. These thioimidophonates are potential ligands towards transition metal ions. The reaction of M(II) acetates (M(II)=Mn(II), Co(II), Ni(II), Cu(II), and Zn(II)) with H1L1 and H1L2 resulted in the formation of solid complexes with the composition (L1/L2)(2)M(II). These compounds were characterized through elemental analysis, electrical conductance, infrared, electronic spectra, nmr, magnetic susceptibilities etc. Vibrational mode assignments of nu(PN), nu(PS), nu(MS), phenyl and methyl group bands are made. Structural and bonding changes are correlated with these vibrational frequencies. All the compounds were screened for their antibacterial and antifungal properties and have exhibited potential activities with MIC (0.09-1.50 microg/ml).
authors.affiliation: Department of Chemistry, Faculty of Natural Sciences, Jamia Millia Islamia (Central University), New Delhi 110025, India.
authors.forename: Vikrant
authors.initials: V
authors.lastname: Kumar
authors.forename: Tansir
authors.initials: T
authors.lastname: Ahamad
authors.forename: N
authors.initials: N
authors.lastname: Nishat
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001559:Benzhydryl Compounds; D002396:Catechols / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D010636:Phenols / Q000737:chemistry*; D013057:Spectrum Analysis; D013329:Structure-Activity Relationship; D028561:Transition Elements; D000098826:Bisphenol A Compounds
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001559:Benzhydryl Compounds; D002396:Catechols; D009942:Organometallic Compounds; D010636:Phenols; D028561:Transition Elements; C034221:catechol; C006780:bisphenol A; D000098826:Bisphenol A Compounds