title: Diagnosis of mandibular osteomyelitis in probable coexisting tumor recurrence: role of Tc-99m ciprofloxacin imaging.
abstract: We demonstrate the use of Tc-99m ciprofloxacin imaging in a follow-up case of squamous cell carcinoma of the tongue post hemi-mandibulectomy with clinical suspicion of local recurrence of osteomyelitis. On Tc-99m ciprofloxacin scan, we observed a focus of sharply increasing radiotracer concentration in the left side of the mandible after 24 hours, indicating active bacterial infection. Histopathologic analysis revealed no evidence of local recurrence, whereas the culture examination showed bacterial growth sensitive to ciprofloxacin. A follow-up Tc-99m ciprofloxacin scan after debridement and 8 weeks of antibiotic treatment showed no focus of tracer concentration in the region of the mandible.
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. drbsingh5144@yahoo.com
authors.forename: Baljinder
authors.initials: B
authors.lastname: Singh
authors.forename: Vikas
authors.initials: V
authors.lastname: Prasad
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Singh
authors.forename: Asseem
authors.initials: A
authors.lastname: Bhatnagar
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
authors.forename: Kumar Ashok
authors.initials: KA
authors.lastname: Gupta
mesh_terms: D002939:Ciprofloxacin / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000150:complications* / Q000000981:diagnostic imaging*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications* / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010019:Osteomyelitis / Q000150:complications* / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C431804:Technetium Tc 99m ciprofloxacin; D002939:Ciprofloxacin