Follow-up care for young adult survivors of cancer: lessons from pediatrics.
BACKGROUND
Recent advances in treatment of childhood cancer have resulted in overall survival rates approaching 75%, but approximately two-thirds experience late-effects related to the disease or treatment. Consequently, recommendations for comprehensive follow-up have been made. As the number of survivors of adult cancers increase, similar concerns about how to provide follow-up and achieve optimal quality of life are being raised. In this paper we propose that management of cancer survivors diagnosed in young adulthood (18-45 years) could benefit from experience gained treating survivors of childhood cancer.


METHODS
We reviewed research relating to differences in survival rates and late-effects; current arrangements for follow-up; effectiveness; and problems in organization of follow-up separately for survivors of child and adult cancers.


RESULTS
A number of models of follow-up were identified. Rationale for follow-up included early identification and treatment of second cancer and late-effects, health promotion and screening. Increasing numbers of survivors and range of late-effects were identified as problems in organizing services. A possible solution is risk-stratified follow-up, currently being developed in pediatrics.


CONCLUSIONS
New models of follow-up are needed that take account of financial costs for health services and survivors' concerns about their current and future health. Implications for continuing refinement of treatment protocols must be an integral part of the service.


CONCLUSIONS
International standards are needed to ensure all survivors have access to expert follow-up care and can benefit from new information that might lead to earlier treatment of late-effects.
Eiser
Christine
C
Department of Psychology, Western Bank, University of Sheffield, Sheffield, S10 2TP, UK. C.Eiser@Sheffield.ac.uk
Absolom
Kate
K
Greenfield
Diana
D
Snowden
John
J
Coleman
Robert
R
Hancock
Barry
B
Davies
Helena
H
D000223:Adaptation, Psychological; D000328:Adult; D001294:Attitude to Health; D002648:Child; D003266:Continuity of Patient Care / Q000191:economics*; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000191:economics / Q000523:psychology* / Q000628:therapy; D010372:Pediatrics; D011379:Prognosis; D011788:Quality of Life; D017741:Survivors / Q000523:psychology; D016896:Treatment Outcome