title: Morphological manifestations for the protective effect of miliacin in organs of immunogenesis after treatment with methotrexate.
abstract: Morphological changes in lymphoid organs induced by antitumor drug methotrexate were studied in 219 male (CBAxC57B1/6)F1 mice. Plant triterpenoid miliacin attenuated the lymphotoxic effect of this drug.
authors.affiliation: Orenburg State Medical Academy.
authors.forename: A D
authors.initials: AD
authors.lastname: Zheleznova
authors.forename: L M
authors.initials: LM
authors.lastname: Zheleznov
authors.forename: A A
authors.initials: AA
authors.lastname: Shtil
authors.forename: B A
authors.initials: BA
authors.lastname: Frolov
mesh_terms: D000818:Animals; D002452:Cell Count; D006965:Hyperplasia; D008221:Lymphoid Tissue / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008727:Methotrexate / Q000633:toxicity*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009929:Organ Size / Q000187:drug effects; D020011:Protective Agents / Q000494:pharmacology*; D013154:Spleen / Q000187:drug effects / Q000473:pathology; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology; D013997:Time Factors; D014315:Triterpenes / Q000494:pharmacology*
chemical_list: D020011:Protective Agents; D014315:Triterpenes; C031972:miliacin; D008727:Methotrexate