A new indication for liver transplantation: nodular regenerative hyperplasia in human immunodeficiency virus-infected patients.
Nodular regenerative hyperplasia is one of the causes of noncirrhotic portal hypertension and has recently been described in human immunodeficiency virus-infected patients, and the potential role of a prothrombotic state and hepatotoxic antiretroviral medication has been suggested. Moreover, it is now established that liver transplantation is feasible in HIV-infected patients. We describe here our experience concerning 3 HIV-infected patients with severe complications of nodular regenerative hyperplasia treated with liver transplantation.
Tateo
Mariagrazia
M
Centre Hépato-Biliaire, AP-HP Hôpital Paul Brousse, Villejuif, France.
Sebagh
Mylène
M
Bralet
Marie-Pierre
MP
Teicher
Elina
E
Azoulay
Daniel
D
Mallet
Vincent
V
Pol
Stanislas
S
Castaing
Denis
D
Samuel
Didier
D
Duclos-Vallée
Jean-Charles
JC
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006965:Hyperplasia / Q000209:etiology / Q000601:surgery; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male