title: Feasibility of laparoscopic sentinel basin dissection for limited resection in early gastric cancer.
abstract: BACKGROUND
  The clinical applications of sentinel node (SN) biopsies in early gastric cancer are limited because of low sensitivity. Sentinel basin (SB) dissection has been suggested as alternative to SN biopsy to improve sensitivity. The aim of this study was to examine the feasibility of laparoscopic SB dissection.
  
  
  METHODS
  Twenty-one gastric adenocarcinoma patients of cT1N0 were enrolled. Technetium 99 m human serum albumin and indocyanine green were injected into the submucosal layer around tumor using an intraoperative endoscope. Green-stained or radioactive lymphatic basins were detected and defined as SBs. After laparoscopic SB dissection, laparoscopy-assisted gastrectomy with D2 lymphadenectomy was performed. Dissected SB nodes and non-SB nodes were evaluated for metastasis pathologically.
  
  
  RESULTS
  The SB detection rate was 95.2%. Numbers of SBs were one in 6, two in 10, and three in 4 patients. The mean number of SB nodes was 7.0. Two patients with lymph node metastasis were diagnosed by SB dissection. Mean time of laparoscopic SB dissection procedure was 15.2 min.
  
  
  CONCLUSIONS
  Above findings suggest that laparoscopic SB dissection is technically feasible, and it might have better sensitivity than SN biopsy. However, the validity of this procedure should be evaluated in a larger series before being clinically applied.
authors.affiliation: Gastric Cancer Branch, National Cancer Center, Korea.
authors.forename: Jun Ho
authors.initials: JH
authors.lastname: Lee
authors.forename: Keun Won
authors.initials: KW
authors.lastname: Ryu
authors.forename: Myeong-Cherl
authors.initials: MC
authors.lastname: Kook
authors.forename: Jong Yeul
authors.initials: JY
authors.lastname: Lee
authors.forename: Chan Gyoo
authors.initials: CG
authors.lastname: Kim
authors.forename: Il Ju
authors.initials: IJ
authors.lastname: Choi
authors.forename: Seok-Ki
authors.initials: SK
authors.lastname: Kim
authors.forename: Seyoun
authors.initials: S
authors.lastname: Jang
authors.forename: Sook Ryun
authors.initials: SR
authors.lastname: Park
authors.forename: Young Woo
authors.initials: YW
authors.lastname: Kim
authors.forename: Byung-Ho
authors.initials: BH
authors.lastname: Nam
authors.forename: Jae-Moon
authors.initials: JM
authors.lastname: Bae
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D005240:Feasibility Studies; D005260:Female; D005743:Gastrectomy; D006801:Humans; D010535:Laparoscopy; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery