title: [Experimental study on electroacupuncture for strengthening gastrointestinal motility in the rat with acute pancreatitis].
abstract: OBJECTIVE
  To explore the mechanism of EA in treatment of acute pancreatitis.
  
  
  METHODS
  Twenty-four healthy male Wistar rats were randomly divided into 3 groups, a control group, a model group and an EA group. In the model group, rat acute pancreatitis model was prearpared by intraperitoneal injection of Caerulein, and in the EA group, EA was given at "Zusanli" (ST 36) and "Tianshu" (ST 25) of the model rat. The gastric emptying rate, small intestinal impelling ratio, myeloperoxidase activity in the pancreas tissue, pathological score of the pancreas and serum amylase were detected.
  
  
  RESULTS
  Compared with the control group, both the gastric emptying rate and the intestinal impelling ratio significantly decreased in the model group (P<0.05), and they significantly increased in the EA group compared with the model group (P<0.05). Myeloperoxidase activity in the pancreas tissue, pathological score of the pancreas and serum amylase activity significantly decreased in the EA group as compared with the model group (P<0.05).
  
  
  CONCLUSIONS
  EA can significantly improve the disturbance of gastrointestinal motility induced by acute pancreatitis and relieve pathological damage of pancreas.
authors.affiliation: Department of Acupuncture, First Clinical College of Harbin Medical University, Harbin 150001, China. hydyylj@163.com
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Xiu-feng
authors.initials: XF
authors.lastname: Shi
authors.forename: Ling-yun
authors.initials: LY
authors.lastname: Zhou
authors.forename: Dong-bo
authors.initials: DB
authors.lastname: Xue
mesh_terms: D000208:Acute Disease; D000681:Amylases / Q000097:blood; D000818:Animals; D015671:Electroacupuncture; D005769:Gastrointestinal Motility; D008297:Male; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000503:physiopathology / Q000628:therapy*; D009195:Peroxidase / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
chemical_list: D009195:Peroxidase; D000681:Amylases