title: Resistance exercise effects on blood glutathione status and plasma protein carbonyls: influence of partial vascular occlusion.
abstract: Seven weight-trained males performed both light resistance with partial occlusion (LRO: 30% 1 RM) and moderate resistance (MR: 70% 1 RM) to failure to ascertain whether blood protein carbonyls (PC) and glutathione status was altered compared to partial occlusion (PO) in a counterbalanced fashion. PO was identical in duration to the LRO session and all sessions were on separate days. PC did not differ for the three conditions at PRE (0.05 nM mg protein(-1)). PC significantly increased for PO and MR over time and was greater than the LRO treatment at POST (0.13 nM mg protein(-1)). The GSSG/TGSH ratio at PRE did not differ across treatments (8%) whereas the ratio at POST was significantly elevated for PO and MR treatments (17%). In contrast, no change occurred for the LRO session at any time. These results indicate that MR to failure and PO can significantly increase blood oxidative stress but LRO did not elicit oxidative stress.
authors.affiliation: Department of Exercise and Sport Science, University of North Carolina at Greensboro, 260 Health and Human Performance Building, Greensboro, NC 27412, USA. ahgoldfa@uncg.edu
authors.forename: A H
authors.initials: AH
authors.lastname: Goldfarb
authors.forename: R S
authors.initials: RS
authors.lastname: Garten
authors.forename: P D M
authors.initials: PD
authors.lastname: Chee
authors.forename: C
authors.initials: C
authors.lastname: Cho
authors.forename: G V
authors.initials: GV
authors.lastname: Reeves
authors.forename: D B
authors.initials: DB
authors.lastname: Hollander
authors.forename: C
authors.initials: C
authors.lastname: Thomas
authors.forename: K S
authors.initials: KS
authors.lastname: Aboudehen
authors.forename: M
authors.initials: M
authors.lastname: Francois
authors.forename: R R
authors.initials: RR
authors.lastname: Kraemer
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm; D005978:Glutathione / Q000097:blood*; D019803:Glutathione Disulfide / Q000097:blood; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D007511:Ischemia / Q000378:metabolism* / Q000503:physiopathology; D008297:Male; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000378:metabolism*; D018384:Oxidative Stress; D010953:Plasma Volume; D050050:Protein Carbonylation; D055070:Resistance Training; D013997:Time Factors; D014654:Vascular Patency; D055815:Young Adult
chemical_list: D019382:Human Growth Hormone; D005978:Glutathione; D019803:Glutathione Disulfide