title: Adapting a generic tuberculosis control operational guideline and scaling it up in China: a qualitative case study.
abstract: BACKGROUND
  The TB operational guideline (the deskguide) is a detailed action guide for county TB doctors aiming to improve the quality of DOTS, while the China national TB policy guide is a guide to TB control that is comprehensive but lacks operational usability for frontline TB doctors. This study reports the process of deskguide adaptation, its scale-up and lessons learnt for policy implications.
  
  
  METHODS
  The deskguide was translated, reviewed, and revised in a working group process. Details of the eight adaptation steps are reported here. An operational study was embedded in the adaptation process. Two comparable prefectures were chosen as pilot and control sites in each of two participating provinces. In the pilot sites, the deskguide was used with the national policy guide in routine in-service training and supervisory trips; while in the control sites, only the national policy guide was used. In-depth interviews and focus groups were conducted with 16 county TB doctors, 16 township doctors, 17 village doctors, 63 TB patients and 57 patient family members. Following piloting, the deskguide was incorporated into the national TB guidelines for county TB dispensary use.
  
  
  RESULTS
  Qualitative research identified that the deskguide was useful in the daily practice of county TB doctors. Patients in the pilot sites had a better knowledge of TB and better treatment support compared with those in the control sites.
  
  
  CONCLUSIONS
  The adaptation process highlighted a number of general strategies to adapt generic guidelines into country specific ones: 1) local policy-makers and practitioners should have a leading role; 2) a systematic working process should be employed with capable focal persons; and 3) the guideline should be embedded within the current programmes so it is sustainable and replicable for further scale-up.
authors.affiliation: Nuffield Centre for International Health and Development, University of Leeds, UK. x.wei@leeds.ac.uk
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Wei
authors.forename: John D
authors.initials: JD
authors.lastname: Walley
authors.forename: Xinyuan
authors.initials: X
authors.lastname: Liang
authors.forename: Feiying
authors.initials: F
authors.lastname: Liu
authors.forename: Xiulei
authors.initials: X
authors.lastname: Zhang
authors.forename: Renzhong
authors.initials: R
authors.lastname: Li
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D002681:China; D023801:Directly Observed Therapy / Q000592:standards*; D004502:Education, Medical, Continuing; D005260:Female; D017144:Focus Groups; D019983:Guideline Adherence; D017408:Guidelines as Topic; D006291:Health Policy; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D010865:Pilot Projects; D010818:Practice Patterns, Physicians' / Q000592:standards*; D036301:Qualitative Research; D014376:Tuberculosis / Q000628:therapy*