title: 18F-FDG-PET/CT as an indicator for resection of pulmonary epithelioid hemangioendothelioma.
abstract: A 60-year-old man with a 7-year history of multiple pulmonary nodules presented to our hospital because the nodules were seen to have increased in size on review of films on a regular medical checkup 1 week earlier. Computed tomography (CT) revealed multiple pulmonary nodules with calcification in the lungs. The largest nodule measuring 2.5 cm in the maximum dimension was lobulated and ill-defined. The patient underwent 18F-fluorodeoxyglucose positron emission tomography/CT (18F-FDG-PET/CT) to evaluate the multiple nodules and to search for a primary lesion. 18F-FDG-PET/CT revealed increased uptake in only two nodules with a standardized uptake value of 4.61 and 2.10, respectively. The two foci with increased 18F-FDG uptake were resected and pathologically proven to be pulmonary epithelioid hemangioendothelioma (PEH). PEH can transform into malignancy with metastasis. An 18F-FDG-PET/CT finding may be an indicator to decide on PEH resection.
authors.affiliation: Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Japan.
authors.forename: Sadahiro
authors.initials: S
authors.lastname: Watanabe
authors.forename: Fuzuki
authors.initials: F
authors.lastname: Yano
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Kita
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Soga
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shinmoto
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kosuda
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ozeki
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Aida
authors.forename: Ikuko
authors.initials: I
authors.lastname: Sakata
mesh_terms: D019788:Fluorodeoxyglucose F18; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D011300:Preoperative Care / Q000379:methods; D011379:Prognosis; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18