title: In vitro withanolide production by Withania somnifera L. cultures.
abstract: In vitro multiple shoots, root, callus and cell suspension cultures of Withania somnifera exhibited the potentiality to produce pharmacologically active withanolides. Multiple shoots cultures exhibited an increase in withanolide A accumulation compared to shoots of the mother plant. In vitro generated root cultures as well as callus and suspension cultures also produced withanolides albeit at lower levels.
authors.affiliation: Central Institute of Medicinal and Aromatic Plants (CIMAP), P. O.-CIMAP, Lucknow-226015, India.
authors.forename: Farzana
authors.initials: F
authors.lastname: Sabir
authors.forename: Neelam S
authors.initials: NS
authors.lastname: Sangwan
authors.forename: Narayan D
authors.initials: ND
authors.lastname: Chaurasiya
authors.forename: Laxmi N
authors.initials: LN
authors.lastname: Misra
authors.forename: Rajender S
authors.initials: RS
authors.lastname: Sangwan
mesh_terms: D002478:Cells, Cultured; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000096:biosynthesis; D035264:Flowers / Q000378:metabolism; D007210:Indoleacetic Acids / Q000378:metabolism; D018515:Plant Leaves / Q000166:cytology / Q000378:metabolism; D018517:Plant Roots / Q000378:metabolism; D018520:Plant Shoots / Q000378:metabolism; D032341:Withania / Q000378:metabolism*; D054358:Withanolides
chemical_list: C433551:3-rhamnopyranosyl(1-4)-glucopyranosyl-12-diacetoxy-20-hydroxywitha-5,24-dienolide; D007210:Indoleacetic Acids; D054358:Withanolides; C030737:indoleacetic acid; D004875:Ergosterol