Immunodeficiency disorders in horses.
Immunodeficiencies are characterized as primary (genetic) or secondary (acquired). Primary immunodeficiencies are relatively uncommon; however, clinically, they present a significant challenge to the practitioner, especially if the underlying disorder goes unrecognized. Secondary immunodeficiencies may present at any age, but failure of passive transfer in neonatal foals is most commonly encountered. This article provides a general overview of clinical signs and diagnosis of primary and secondary immunodeficiencies currently recognized in horses.
Crisman
Mark V
MV
Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA. farmuse@vt.edu
Scarratt
W Kent
WK
D000361:Agammaglobulinemia / Q000662:veterinary*; D000818:Animals; D000833:Animals, Suckling / Q000276:immunology; D003126:Colostrum / Q000276:immunology; D006734:Horse Diseases / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology; D006736:Horses; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive / Q000662:veterinary; D007075:Immunoglobulin M / Q000172:deficiency; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D016511:Severe Combined Immunodeficiency / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary
D007075:Immunoglobulin M