title: Percutaneous aortic valve replacement: a novel design of the delivery and deployment system.
abstract: The frontier of percutaneous aortic valve replacement is challenged by hemodynamic and anatomic obstacles in the precise positioning of the device. With vital structures such as the mitral valve apparatus and the coronary ostia on either side, the margin of error is only within a few millimeters in the placement of the percutaneous aortic valve. An optimal system of delivery and deployment of this device has yet to be made commercially available. A novel design of a system of delivery and deployment of currently investigational aortic valved-stent is presented. In the proposed procedural and equipment strategy, the local hemodynamic and anatomic conditions are controlled to allow for precise placement of the device, and overall improvement of the patient stability and safety can be made possible. Continued efforts in innovative designs in this area are encouraged such that the percutaneous valvular intervention can become mainstay as it has in the arena of percutaneous coronary intervention.
authors.affiliation: HOCOR Cardiovascular Technologies, LLC, Honolulu, Hawaii, USA. hoart@mac.com
authors.forename: Paul C
authors.initials: PC
authors.lastname: Ho
mesh_terms: D001021:Aortic Valve / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000601:surgery; D004867:Equipment Design; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D015607:Stents