Chemical tools for functional studies of glycans.
In recent years a variety of chemical approaches have been developed for elucidating the molecular basis of biological processes in which glycans participate. The chemical technologies uncovered have greatly influenced the progress of glycomics research programs. This tutorial review highlights recent advances in chemical tools which have been developed and their applications in studies aimed at gaining a better understanding of the roles that glycans play in biological processes.
Park
Sungjin
S
Department of Chemistry, Yonsei University, Seoul, Korea.
Lee
Myung-Ryul
MR
Shin
Injae
I
D000818:Animals; D006023:Glycoproteins / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D037102:Lectins / Q000037:antagonists & inhibitors / Q000378:metabolism; D046228:Microarray Analysis; D011134:Polysaccharides / Q000737:chemistry* / Q000378:metabolism*
D006023:Glycoproteins; D037102:Lectins; D011134:Polysaccharides; D006026:Glycoside Hydrolases