BFA effects are tissue and not just plant specific.
Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified.
Robinson
David G
DG
Department of Cell Biology, Heidelberg Institute for Plant Sciences, University of Heidelberg, 69120 Heidelberg, Germany.
Langhans
Markus
M
Saint-Jore-Dupas
Claude
C
Hawes
Chris
C
D020126:Brefeldin A / Q000494:pharmacology*; D006056:Golgi Apparatus / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D018546:Hypocotyl / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D018515:Plant Leaves / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D010944:Plants / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure
D020126:Brefeldin A