title: Capabilities of microbore columns coupled to inductively coupled plasma mass spectrometry in speciation of arsenic and selenium.
abstract: The performance of microHPLC-microconcentric nebulizer-inductively coupled plasma-mass spectrometry (ICP-MS) coupling for the simultaneous determination of As(III), As(V), monomethylarsenic acid (MMA), dimethylarsinic acid (DMA), selenite (SeIV) and selenate (SeVI) in water was evaluated. The accurate reduction of the off-column dead volume, specially the capillary of the micronebulizer, as well as the optimization of chromatographic conditions led to the claimed advantages expected for microbore columns: a significant diminution of sample and solvent consumption without sacrificing sensitivity and the overall resolution in faster analysis time (less than 5 min). Detection limits are in the range 0.03-0.04 microg L(-1) for arsenic species and 0.35 microg L(-1) for selenium species. The developed method was validated by analysing different spiked environmental water samples. Linearity, tested up to 50 microg L(-1), showed correlation coefficients above 0.999 and no matrix effect for high saline water samples. Good accuracy and repeatability was obtained for spiked influent and effluent water treatment plant.
authors.affiliation: Research Institute for Pesticides and Water, Universitat Jaume I, Avgda. Sos Baynat s/n, E-12071 Castelló, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Castillo
authors.forename: A F
authors.initials: AF
authors.lastname: Roig-Navarro
authors.forename: O J
authors.initials: OJ
authors.lastname: Pozo
mesh_terms: D001151:Arsenic / Q000032:analysis*; D002101:Cacodylic Acid / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D015203:Reproducibility of Results; D064586:Selenic Acid; D012643:Selenium / Q000032:analysis*; D018036:Selenium Compounds / Q000032:analysis; D018038:Sodium Selenite / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis; D014881:Water Supply / Q000032:analysis
chemical_list: D018036:Selenium Compounds; D014874:Water Pollutants, Chemical; D002101:Cacodylic Acid; D012643:Selenium; D018038:Sodium Selenite; D064586:Selenic Acid; D001151:Arsenic