Bioactive natural products from endophytes: a review.
Endophytes, microorganisms that reside in the internal tissues of living plants without causing any immediate overt negative effects, have been found in every plant species examined to date and recognized as potential sources of novel natural products for exploitation in medicine, agriculture, and industry with more and more bioactive natural products isolated from the microorganisms. In this review, we focus mainly on bioactive natural products from endophytic microorganisms by their different functional roles. The prospect and facing problems of isolating natural products from endophytes are also discussed.
Guo
B
B
Shanghai Key Laboratory of Agrobiotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200030, PR China.
Wang
Y
Y
Sun
X
X
Tang
K
K
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry*; D017753:Ecosystem; D005658:Fungi / Q000737:chemistry*; D006801:Humans; D010944:Plants / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D001688:Biological Products