Study of distortion-product otoacoustic emissions during hypothermia in humans.
OBJECTIVE
To evaluate the function of cochlear outer hair-cells under the influence of extra-corporeal circulation and moderate hypothermia during cardiac surgery.


METHODS
Prospective clinical study.


METHODS
Distortion-product otoacoustic emissions (DPOAE) were registered before surgery, immediately after general anesthesia induction, during extra-corporeal circulation with moderate hypothermia and after the surgical procedure.


RESULTS
Comparison of response-amplitudes before and after surgery and before and after general anesthesia initiation did not demonstrate statistical difference. Comparison of amplitudes before and after extra-corporeal circulation with moderate hypothermia demonstrated a statistically significant decrease in responses amplitudes during hypothermia.


CONCLUSIONS
The amplitudes of DPOAE decreased during moderate hypothermia induced during extra-corporeal circulation.
Borin
Andrei
A
Cruz
Oswaldo Laércio Mendonça
OL
D000328:Adult; D002318:Cardiovascular Diseases / Q000601:surgery; D005112:Extracorporeal Circulation; D018072:Hair Cells, Auditory, Outer / Q000502:physiology*; D006801:Humans; D007036:Hypothermia, Induced; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D010469:Perceptual Distortion / Q000502:physiology*; D011446:Prospective Studies