title: A non-cross-linked soluble polystyrene-supported ruthenium catalyst for carbenoid transfer reactions.
abstract: Ruthenium nanoparticles supported on non-cross-linked soluble polystyrene were prepared by reacting [RuCl(2)(C(6)H(5)CO(2)Et)](2) with polystyrene in open air. They effectively catalyze intra- and intermolecular carbenoid insertion into C-H and N-H bonds, alkene cyclopropanation, and ammonium ylide/[2,3]-sigmatropic rearrangement reactions. This supported ruthenium catalyst is much more reactive than [RuCl(2)(p-cymene)](2) and [Ru(Por)CO] for catalytic intermolecular carbenoid C-H bond insertion into saturated alkanes. By using alpha-diazoacetamide as a substrate for intramolecular carbenoid C-H insertion, the supported ruthenium catalyst can be recovered and reused for ten successive iterations without significant loss of activity.
authors.affiliation: Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
authors.forename: Matthew Kwok-Wai
authors.initials: MK
authors.lastname: Choi
authors.forename: Wing-Yiu
authors.initials: WY
authors.lastname: Yu
authors.forename: Man-Ho
authors.initials: MH
authors.lastname: So
authors.forename: Cong-Ying
authors.initials: CY
authors.lastname: Zhou
authors.forename: Qing-Hai
authors.initials: QH
authors.lastname: Deng
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che
mesh_terms: D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry; D003521:Cyclopropanes / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D011137:Polystyrenes / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D012995:Solubility; D013057:Spectrum Analysis
chemical_list: D000475:Alkenes; D003432:Cross-Linking Reagents; D003521:Cyclopropanes; D011137:Polystyrenes; C030011:carbene; D012428:Ruthenium; C030797:cyclopropane; D008697:Methane