Molecular mechanism of apoptosis induction by resveratrol, a natural cancer chemopreventive agent.
In efforts to identify naturally occurring compounds that act as protective agents, resveratrol, a phytoalexin existing in wine, has attracted much interest because of its diverse pharmacological characteristics. Considering that apoptosis induction is the most potent defense approach for cancer treatment, we have tried to summarize our present understanding of apoptosis induction by resveratrol based on the two major apoptosis pathways.
Fan
Enguo
E
College of Life Sciences, Nankai University, Tian Jin, China.
Jiang
Sha
S
Zhang
Lijuan
L
Bai
Yuhua
Y
D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D001688:Biological Products / Q000494:pharmacology*; D018890:Chemoprevention / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*; D000077185:Resveratrol; D015398:Signal Transduction / Q000187:drug effects; D013267:Stilbenes / Q000494:pharmacology*
D016588:Anticarcinogenic Agents; D001688:Biological Products; D013267:Stilbenes; D000077185:Resveratrol