A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT).
Two patients, one with malignant pleural mesothelioma and one with a malignant short spindle cell tumor, received boron neutron capture therapy (BNCT). In each case, the tumors regressed or remained stable in size for 3-6 months following BNCT. No acute or late adverse events higher than grade 2 were observed.
Suzuki
Minoru
M
Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kumatori-cho, Sennan-gun, Osaka, Japan. msuzuki@rri.kyoto-u.ac.jp
Endo
Kazuo
K
Satoh
Hiroaki
H
Sakurai
Yoshinori
Y
Kumada
Hiroaki
H
Kimura
Hiroyuki
H
Masunaga
Shinichiro
S
Kinashi
Yuko
Y
Nagata
Kenji
K
Maruhashi
Akira
A
Ono
Koji
K
D000328:Adult; D001896:Boron Compounds / Q000627:therapeutic use*; D016754:Boron Neutron Capture Therapy / Q000379:methods*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000532:radiotherapy*; D008875:Middle Aged; D010865:Pilot Projects; D010997:Pleural Neoplasms / Q000532:radiotherapy*
D001896:Boron Compounds