title: Effect of graded levels of dietary nitrite on pulmonary hypertension in broiler chickens and dilatory cardiomyopathy in turkey poults.
abstract: In two separate trials, day-old broiler chicks and turkey poults were fed graded levels of dietary sodium nitrite in order to investigate the possible role of nitrite-induced methaemoglobinaemia on the incidence of chicken pulmonary hypertension and spontaneous turkey cardiomyopathy (STC). A transient low level of methaemoglobinaemia was observed after 7 days of exposure to dietary nitrite, but the levels returned to normal afterwards in spite of the presence of nitrite in the diet throughout the experiment. No effect on pulmonary hypertension, as measured by the right ventricle weight to total ventricle weight ratio, was observed in chickens exposed to dietary nitrite. The group of turkey poults receiving 1200 mg/kg nitrite in the diet had a higher incidence of STC than controls (20 v. 5%), although the difference was not statistically significant. The levels of nitrite-induced methaemoglobinaemia were probably too low to be considered as the aetiology of increased STC incidence.
authors.affiliation: Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Santafe de Bogota, D.C. Colombia.
authors.forename: G J
authors.initials: GJ
authors.lastname: Diaz
authors.forename: R J
authors.initials: RJ
authors.lastname: Julian
authors.forename: E J
authors.initials: EJ
authors.lastname: Squires