title: [Radiation and nonradiation factors in thyroid pathology development for Chernobyl cleanup workers--residents of Mayak PA affected zone].
abstract: Thyroid state study was been carried out for Chernobyl NPP accident liquidators living in Ozyorsk, the city, located in the nuclear facility affected zone (Mayak PA). In total 531 individuals were examined. Thyroid assessment was made basing on physical examination, on ultrasound study and on hormones measurement of thyroid stimulating hormone, free thyroxine and thyroid peroxidase antibody. Screening revealed thyroid pathology for 27% of clean-up workers. As a result of the study carried the following conclusions were made: thyroid disease prevalence among the Ozyorsk residents participated in the breakdown elimination after Chernobyl accident was not differ from the individuals who didn't take part in this work; the prevalence of thyroid disease in liquidators was significantly connected with non radiation risk factors: with gender (for women compared to men), RR = 4.0, 95% CI 2.9-5.5; with age (over 60 years old vs under 60 years old), RR for women was 1.7; 95% CI 1.0-3.0 and for men -1.9; 95% CI 1.1-3.2; with hereditary predisposition, RR for autoimmune thyroiditis was 3.3, 95% CI 1.4-7.9.
authors.forename: E I
authors.initials: EI
authors.lastname: Rabinovich
authors.forename: S V
authors.initials: SV
authors.lastname: Povolotskaia
authors.forename: V B
authors.initials: VB
authors.lastname: Shorokhova
authors.forename: V A
authors.initials: VA
authors.lastname: Turdakova
authors.forename: S N
authors.initials: SN
authors.lastname: Sokolova
authors.forename: V A
authors.initials: VA
authors.lastname: Privalov
authors.forename: E F
authors.initials: EF
authors.lastname: Ryzhova
authors.forename: V P
authors.initials: VP
authors.lastname: Ryzhov
authors.forename: A N
authors.initials: AN
authors.lastname: Egorov
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D047852:Chernobyl Nuclear Accident; D015331:Cohort Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology*; D015995:Prevalence; D011832:Radiation Injuries / Q000453:epidemiology*; D011848:Radioactive Pollutants; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D013959:Thyroid Diseases / Q000453:epidemiology*; D013961:Thyroid Gland / Q000473:pathology / Q000528:radiation effects; D014505:Urban Population
chemical_list: D011848:Radioactive Pollutants