title: Adult-to-embryo chemical signaling in the regulation of larval development in trochophore animals: cellular and molecular mechanisms.
abstract: The regulation of larval development by starved adults occurs in both freshwater snails, Helisoma trivolvis and marine polychaetes, Platynereis dumerilii. Serotonin (5-HT) links this environmental signal which is detected by larval apical sensory neurons to changes in larval development. A profile of the stage-dependent expression of 5-HT receptors and coupled G proteins is essential in this regulatory mechanism. The final effect on development depends on the modulation of the activity of the larval digestive system.
authors.affiliation: Department of Comparative Physiology, Institute for Developmental Biology, Moscow, Russia. lena_vor@mail.ru
authors.forename: Elena E
authors.initials: EE
authors.lastname: Voronezhskaya
authors.forename: K I
authors.initials: KI
authors.lastname: Glebov
authors.forename: Marina Yu
authors.initials: MY
authors.lastname: Khabarova
authors.forename: E G
authors.initials: EG
authors.lastname: Ponimaskin
authors.forename: L P
authors.initials: LP
authors.lastname: Nezlin
mesh_terms: D000818:Animals; D007814:Larva / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D008954:Models, Biological; D011077:Polychaeta / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D011985:Receptors, Serotonin / Q000378:metabolism; D015398:Signal Transduction; D012908:Snails / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*
chemical_list: D043562:Receptors, G-Protein-Coupled; D011985:Receptors, Serotonin