Recognition of guests by water-stabilized cavitand hosts.
Water stabilized, deep cavitands with three walls and an open side are shown to be receptors for amines and ammonium cations bearing bulky aliphatic groups. The missing wall allows the binding of guests not accommodated by the four-walled counterparts.
Lledó
Agustí
A
The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Hooley
Richard J
RJ
Rebek
Julius
J
D000218:Adamantane / Q000031:analogs & derivatives / Q000737:chemistry; D047250:Calixarenes / Q000138:chemical synthesis / Q000737:chemistry*; D004988:Ethers, Cyclic / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D008968:Molecular Conformation; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012118:Resorcinols / Q000138:chemical synthesis / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D004988:Ethers, Cyclic; D000644:Quaternary Ammonium Compounds; D012118:Resorcinols; C442939:cavitand; C466160:resorcinarene; D014867:Water; D047250:Calixarenes; D010649:Phenylalanine; D000218:Adamantane