18F-FDG-PET/CT as an indicator for resection of pulmonary epithelioid hemangioendothelioma.
A 60-year-old man with a 7-year history of multiple pulmonary nodules presented to our hospital because the nodules were seen to have increased in size on review of films on a regular medical checkup 1 week earlier. Computed tomography (CT) revealed multiple pulmonary nodules with calcification in the lungs. The largest nodule measuring 2.5 cm in the maximum dimension was lobulated and ill-defined. The patient underwent 18F-fluorodeoxyglucose positron emission tomography/CT (18F-FDG-PET/CT) to evaluate the multiple nodules and to search for a primary lesion. 18F-FDG-PET/CT revealed increased uptake in only two nodules with a standardized uptake value of 4.61 and 2.10, respectively. The two foci with increased 18F-FDG uptake were resected and pathologically proven to be pulmonary epithelioid hemangioendothelioma (PEH). PEH can transform into malignancy with metastasis. An 18F-FDG-PET/CT finding may be an indicator to decide on PEH resection.
Watanabe
Sadahiro
S
Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Japan.
Yano
Fuzuki
F
Kita
Tamotsu
T
Soga
Shigeyoshi
S
Shinmoto
Hiroshi
H
Kosuda
Shigeru
S
Ozeki
Yuichi
Y
Aida
Shinsuke
S
Sakata
Ikuko
I
D019788:Fluorodeoxyglucose F18; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D011300:Preoperative Care / Q000379:methods; D011379:Prognosis; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18