title: Immunodeficiency disorders in horses.
abstract: Immunodeficiencies are characterized as primary (genetic) or secondary (acquired). Primary immunodeficiencies are relatively uncommon; however, clinically, they present a significant challenge to the practitioner, especially if the underlying disorder goes unrecognized. Secondary immunodeficiencies may present at any age, but failure of passive transfer in neonatal foals is most commonly encountered. This article provides a general overview of clinical signs and diagnosis of primary and secondary immunodeficiencies currently recognized in horses.
authors.affiliation: Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA. farmuse@vt.edu
authors.forename: Mark V
authors.initials: MV
authors.lastname: Crisman
authors.forename: W Kent
authors.initials: WK
authors.lastname: Scarratt
mesh_terms: D000361:Agammaglobulinemia / Q000662:veterinary*; D000818:Animals; D000833:Animals, Suckling / Q000276:immunology; D003126:Colostrum / Q000276:immunology; D006734:Horse Diseases / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology; D006736:Horses; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive / Q000662:veterinary; D007075:Immunoglobulin M / Q000172:deficiency; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D016511:Severe Combined Immunodeficiency / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary
chemical_list: D007075:Immunoglobulin M