[Severe phenotypes in sarcoidosis. Non-pulmonary involvement].
When involving some organ systems, sarcoidosis can affect functional outcome and/or constitute a life-threatening condition. Neurological expression is often overt and thus easily diagnosed. However, diagnosing heart involvement requires a thorough history taking and at least one systematic electrocardiogram. These lesions are serious and require a corticosteroid therapy, initiated in most cases at the daily dose of 1 mg/kg. This therapy should be combined with organ-specific treatments, always necessary though not sufficient.
Chapelon-Abric
Catherine
C
Service de médecine interne 2, groupe hospitalier Pitié-Salpêtrière, 75651 Paris Cedex 13, France. catherine.chapelon@psl.aphp.fr
D009202:Cardiomyopathies / Q000150:complications; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D007818:Laryngeal Diseases / Q000150:complications; D009422:Nervous System Diseases / Q000150:complications; D010641:Phenotype; D012507:Sarcoidosis / Q000150:complications*; D012720:Severity of Illness Index