An expedient asymmetric synthesis of platencin.
A short and efficient synthesis of enone 3, a key intermediate in the total synthesis of platencin (2), based on an intramolecular Diels-Alder reaction is described.
Nicolaou
K C
KC
Chemical Synthesis Laboratory@Biopolis, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, The Helios Block, #03-08, Singapore 138667. kcn@scripps.edu
Toh
Qiao-Yan
QY
Chen
David Y-K
DY
D000627:Aminophenols / Q000138:chemical synthesis*; D008956:Models, Chemical; D011083:Polycyclic Compounds / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000627:Aminophenols; D011083:Polycyclic Compounds; C520340:platencin