title: [Trends in the indications for penetrating keratoplasty].
abstract: OBJECTIVE
  To identify the indications for penetrating keratoplasty at the Department of Ophthalmology of the Santa Casa of São Paulo from January 1996 to December 2005 and to compare them with those from January 1991 to December 1995.
  
  
  METHODS
  Charts of patients who had undergone penetrating keratoplasty from January 1996 to December 2006 were retrospectively reviewed.
  
  
  RESULTS
  There were 587 keratoplasties done in this period. The average age of patients was 49.6 +/- 21.1 years (range 1 to 91 years). The most common indications were infectious keratitis (17.9%), trauma (16%), pseudophakic bullous keratopathy (14.7%), keratoconus (13.1%), regrafts (12.8%) and herpetic keratitis (6.6%).
  
  
  CONCLUSIONS
  The leading indications for penetrating keratoplasty were infectious keratitis, trauma, bullous keratopathy, herpetic keratitis. There was a decreasing trend in penetrating keratoplasty for keratoconus and regraft during the last 10 years.
authors.affiliation: Departamento de Oftalmologia, Santa Casa de São Paulo, São Paulo, SP, Brasil. fabianasano@hotmail.com
authors.forename: Fabiana Tiemi
authors.initials: FT
authors.lastname: Sano
authors.forename: Paulo Elias Correa
authors.initials: PE
authors.lastname: Dantas
authors.forename: Wilmar Roberto
authors.initials: WR
authors.lastname: Silvino
authors.forename: Janaina Zamuner
authors.initials: JZ
authors.lastname: Sanchez
authors.forename: Ronaldo Yuiti
authors.initials: RY
authors.lastname: Sano
authors.forename: Fabio
authors.initials: F
authors.lastname: Adams
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Nishiwaki-Dantas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D003316:Corneal Diseases / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D015948:Keratoplasty, Penetrating / Q000706:statistics & numerical data / Q000639:trends*; D008297:Male; D008875:Middle Aged; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D055815:Young Adult