title: Dynamic infrared imaging in identification of breast cancer tissue with combined image processing and frequency analysis.
abstract: Five combinations of image-processing algorithms were applied to dynamic infrared (IR) images of six breast cancer patients preoperatively to establish optimal enhancement of cancer tissue before frequency analysis. mid-wave photovoltaic (PV) IR cameras with 320x254 and 640x512 pixels were used. The signal-to-noise ratio and the specificity for breast cancer were evaluated with the image-processing combinations from the image series of each patient. Before image processing and frequency analysis the effect of patient movement was minimized with a stabilization program developed and tested in the study by stabilizing image slices using surface markers set as measurement points on the skin of the imaged breast. A mathematical equation for superiority value was developed for comparison of the key ratios of the image-processing combinations. The ability of each combination to locate the mammography finding of breast cancer in each patient was compared. Our results show that data collected with a 640x512-pixel mid-wave PV camera applying image-processing methods optimizing signal-to-noise ratio, morphological image processing and linear image restoration before frequency analysis possess the greatest superiority value, showing the cancer area most clearly also in the match centre of the mammography estimation.
authors.affiliation: Tampere University Hospital, Medical Imaging Centre, Tampere, Finland. risto.joro@fma.fi
authors.forename: R
authors.initials: R
authors.lastname: Joro
authors.forename: A-L
authors.initials: AL
authors.lastname: Lääperi
authors.forename: S
authors.initials: S
authors.lastname: Soimakallio
authors.forename: R
authors.initials: R
authors.lastname: Järvenpää
authors.forename: T
authors.initials: T
authors.lastname: Kuukasjärvi
authors.forename: T
authors.initials: T
authors.lastname: Toivonen
authors.forename: R
authors.initials: R
authors.lastname: Saaristo
authors.forename: P
authors.initials: P
authors.lastname: Dastidar
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007259:Infrared Rays; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted