title: [Obtaining antibodies to 1,4-dihydropyridine calcium channel blockers].
abstract: Immunization of rabbits with amlodipine conjugated with horseradish peroxidase resulted in raising polyclonal antibodies that allowed group determination of 1,4-dihydropyridine calcium channel blockers in aqueous solutions by ELISA with a sensitivity of 0.1 to 1.0 ng/ml for amlodipine, felodipine, nifedipine, and isradipine.
authors.forename: A A
authors.initials: AA
authors.lastname: Burkin
authors.forename: M A
authors.initials: MA
authors.lastname: Murkin
mesh_terms: D000818:Animals; D000906:Antibodies / Q000737:chemistry / Q000276:immunology*; D002121:Calcium Channel Blockers / Q000032:analysis / Q000276:immunology*; D004095:Dihydropyridines / Q000032:analysis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D008297:Male; D011817:Rabbits; D012680:Sensitivity and Specificity
chemical_list: D000906:Antibodies; D002121:Calcium Channel Blockers; D004095:Dihydropyridines