Merkel cell carcinoma with a follicular lymphocytic infiltrate: report of 2 cases.
Merkel cell carcinoma (MCC) with a follicular lymphocytic infiltrate of the dermis was first reported by Bastian et al in 1996. Thereafter there were no further reports of such a morphological variant of MCC. We present here 2 cases of MCC characterized by foci of a dense lymphocytic infiltrate with the formation of lymphoid follicles. This feature may produce a potential diagnostic pitfall, rendering a lymphomatous appearance to the tumor.
Vazmitel
Marina
M
Academy of Medical Postgraduate Education of Belarus, Minsk, Republic of Belarus.
Michal
Michal
M
Kempf
Werner
W
Mukensnabl
Petr
P
Kazakov
Dmitry V
DV
D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000276:immunology* / Q000378:metabolism / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000276:immunology*; D008232:Lymphoproliferative Disorders / Q000473:pathology; D012878:Skin Neoplasms / Q000276:immunology* / Q000378:metabolism / Q000473:pathology*