Plasma-sprayed CaTiSiO5 ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity.
Novel Ca-Si-Ti-based sphene (CaTiSiO5) ceramics possess excellent chemical stability and cytocompatibility. The aim of this study was to prepare sphene coating on titanium alloy (Ti-6Al-4V) for orthopaedic applications using the plasma spray method. The phase composition, surface and interface microstructure, coating thickness, surface roughness and bonding strength of the plasma-sprayed sphene coating were analysed using X-ray diffraction, scanning electron microscopy, atomic force microscopy and the standard mechanical testing of the American Society for Testing and Materials, respectively. The results indicated that sphene coating was obtained with a uniform and dense microstructure at the interface of the Ti-6Al-4V surface and the thickness and surface roughness of the coating were approximately 150 and 10 microm, respectively. Plasma-sprayed sphene coating on Ti-6Al-4V possessed a significantly improved bonding strength and chemical stability compared with plasma-sprayed hydroxyapatite (HAp) coating. Plasma-sprayed sphene coating supported human osteoblast-like cell (HOB) attachment and significantly enhanced HOB proliferation and differentiation compared with plasma-sprayed HAp coating and uncoated Ti-6Al-4V. Taken together, plasma-sprayed sphene coating on Ti-6Al-4V possessed excellent bonding strength, chemical stability and cellular bioactivity, indicating its potential application for orthopaedic implants.
Wu
Chengtie
C
Biomaterials and Tissue Engineering Research Unit, School of AMME, University of Sydney, Sydney 2006, Australia.
Ramaswamy
Yogambha
Y
Liu
Xuanyong
X
Wang
Guocheng
G
Zreiqat
Hala
H
D000469:Alkaline Phosphatase / Q000378:metabolism; D000497:Alloys; D001842:Bone and Bones / Q000166:cytology / Q000187:drug effects / Q000201:enzymology; D048708:Cell Growth Processes / Q000187:drug effects; D002516:Ceramics / Q000737:chemistry* / Q000494:pharmacology; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D020007:Implants, Experimental; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D010006:Osteoblasts / Q000166:cytology / Q000187:drug effects / Q000201:enzymology; D017640:Silicates / Q000737:chemistry; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology; D014961:X-Ray Diffraction
D000497:Alloys; D020099:Coated Materials, Biocompatible; D017640:Silicates; C031462:titanium alloy (TiAl6V4); D014025:Titanium; D000469:Alkaline Phosphatase