title: Antimicrobial activity of essential oil and major constituents of Salvia chloroleuca.
abstract: The aerial parts of Salvia chloroleuca were collected at full flowering stage at Shahrestanak (Tehran province of Iran). The essential oil was isolated by hydrodistillation and analyzed by combination of capillary GC and GC-MS. Thirty-four components were identified, representing 98.5% of the total oil. beta-Pinene (10.6%), alpha-pinene (9.0%), beta-caryophyllene (9.0%), 1,8-cineole (9.0%) and carvacrol (7.9%) were the main components. The in vitro antimicrobial activity of the essential oil of S. chloroleuca was studied against seven Gram-positive and Gram-negative bacteria (Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) and three fungi (Candida albicans, Saccharomyces cerevisiae and Aspergillus niger); the disc diffusion method and MIC values indicated that the oil exhibited moderate to high antimicrobial activity.
authors.affiliation: Department of Marine Biology, Faculty of Sciences, Hormozgan University, Bandar Abbas, Iran. morteza110110@gmail.com
authors.forename: Morteza
authors.initials: M
authors.lastname: Yousefzadi
authors.forename: Ali
authors.initials: A
authors.lastname: Sonboli
authors.forename: Samad Nejad
authors.initials: SN
authors.lastname: Ebrahimi
authors.forename: Seid Hasan
authors.initials: SH
authors.lastname: Hashemi
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D001892:Camphanes; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification* / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D005839:Gentamicins / Q000494:pharmacology; D007711:Klebsiella pneumoniae / Q000187:drug effects; D009761:Nystatin / Q000494:pharmacology; D009822:Oils, Volatile / Q000302:isolation & purification* / Q000494:pharmacology*; D053723:Panax notoginseng; D035261:Plant Components, Aerial / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D027561:Salvia miltiorrhiza; D013210:Staphylococcus / Q000187:drug effects; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001892:Camphanes; D004365:Drugs, Chinese Herbal; D005839:Gentamicins; D009822:Oils, Volatile; C000604051:danshen dripping pill; D009761:Nystatin; D013752:Tetracycline