SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles.
SCK nanoparticles having differing core thermal characteristics were designed and evaluated as thermoresponsive drug delivery systems of doxorubicin for the killing of cancerous cells.
Nyström
Andreas M
AM
Center for Materials Innovation, Department of Chemistry and Department of Radiology, Washington University in Saint Louis, Saint Louis, Missouri 63130-4899, USA.
Xu
Zhiqiang
Z
Xu
Jinqi
J
Taylor
Sara
S
Nittis
Thalia
T
Stewart
Sheila A
SA
Leonard
Jeffrey
J
Wooley
Karen L
KL
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D004317:Doxorubicin / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D053758:Nanoparticles / Q000737:chemistry*; D013696:Temperature
D000970:Antineoplastic Agents; D004337:Drug Carriers; D004317:Doxorubicin