Antimycotic potential of Crataeva religiosa Hook and Forst against some selected fungal pathogens.
Crataeva religiosa Hook and Forst belonging to family Capparidaceae (Cappaceae) was selected based on its ethnopharmacological uses like diuretic, laxative, lithonotriptic, antirheumatic, antiperiodic, bitter tonic, rubifacient and counterirritant and was investigated to evaluate in vitro antimycotic potential of petroleum ether, chloroform, ethanolic and aqueous extracts against Candida albicans, Candida tropicalis, Candida krusei, Cryptococcus marinus and Aspergillus niger by disc diffusion method. The minimum inhibitory concentrations of C. religiosa extracts were found in the range of 0.062 - 0.5 mg/disc. The ethanolic extract significantly inhibits the growth of selected fungal pathogens, whereas aqueous extract do not show zone of inhibition against the tested Candida species. The results indicate the possible therapeutic uses of the plant as a potent antifungal agent.
Sahoo
Sabuj
S
University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bhubaneswar-751004, Orissa, India. sabujbiotech@rediffmail.com
Mishra
Sagar K
SK
Panda
Prasana K
PK
Tripathy
Shyamlendu
S
Mishra
Satya R
SR
Ellaiah
Poluri
P
Dash
Sashi K
SK
D000935:Antifungal Agents / Q000494:pharmacology*; D031483:Capparaceae; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*
D000935:Antifungal Agents; D010936:Plant Extracts