Fluoride oral retention after professional topical application in children with caries activity: effect of the immediate water consumption.
OBJECTIVE
Since there is no agreement about the time patients must refrain from drinking or eating after a professional application of acidulated phosphate fluoride (APF), the purpose of this study was to evaluate the effect of water consumption on fluoride in saliva.


METHODS
This blind randomized crossover in vivo study involved children who received a professional APF gel application followed by either drinking a glass of water (experimental group) or without rinsing, drinking, or eating (control group) for 2 hours. The nonstimulated saliva was collected at 0, 5, 15, 30, 60, and 120 minutes following the professional APF application. After a 7-day washout period, the control and treatment groups were switched.


RESULTS
There was a statistically significant difference in the fluoride retention between groups in the times 0 to 5 minutes (P<.05).


CONCLUSIONS
The data suggest that the recommendation of asking patients to refrain from drinking water for 30 minutes following the professional APF application is excessive and can be reduced to 15 minutes.
Lopes
Mariana de Figueiredo
Mde F
Faculty of Dentistry, Federal University of Maranhão, São Luís, Brazil.
Braga
Juliana de Kássia Silva
Jde K
de Oliveira
Ana Emília Figueiredo
AE
Cavalcante
Paulo Roberto Saraiva
PR
Ribeiro
Cecilia Cláudia Costa
CC
D000149:Acidulated Phosphate Fluoride / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002648:Child; D018592:Cross-Over Studies; D003731:Dental Caries / Q000378:metabolism / Q000517:prevention & control*; D004326:Drinking / Q000502:physiology*; D004435:Eating / Q000502:physiology; D005260:Female; D005460:Fluorides, Topical / Q000493:pharmacokinetics* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012463:Saliva / Q000378:metabolism*; D016037:Single-Blind Method; D013997:Time Factors
D002327:Cariostatic Agents; D005460:Fluorides, Topical; D000149:Acidulated Phosphate Fluoride