title: [Prelymphoma as a stage of malignant lymphoma (baboon malignant lymphoma model)].
abstract: Ten percent of the monkeys (more then 400 animals) from P. hamadrias herd of Sukhumi monkey colony died of a 20 year-long enzootic of malignant lymphoma associated with STLV-1 retrovirus. Retrospective analysis revealed regular (in more than 80% of cases) development of prelymphoma preceded by malignant process for a considerable time (up to 10 years or more). Prelymphoma occurred as mild hemopoietic inhibition including lymphopoiesis. Clinico-morphological signs of prelymphoma were: hypoplasia, edema and discomplexation in lymph nodes, anemia and inflammatory, i. e. degenerative lesions of the skin and mucous membranes.
authors.forename: L A
authors.initials: LA
authors.lastname: Iakovleva
mesh_terms: D000818:Animals; D006800:Deltaretrovirus Infections / Q000473:pathology* / Q000503:physiopathology*; D004195:Disease Models, Animal; D005260:Female; D008223:Lymphoma / Q000473:pathology* / Q000503:physiopathology* / Q000821:virology; D038041:Lymphopoiesis; D008297:Male; D009367:Neoplasm Staging; D048529:Papio hamadryas; D012189:Retrospective Studies; D015303:Simian T-lymphotropic virus 1