Comparison of laboratory-based and phylogenetic methods to distinguish between Haemophilus influenzae and H. haemolyticus.
New methods to distinguish between nontypeable Haemophilus influenzae and nonhemolytic H. haemolyticus were compared. The results of iga variable region hybridization to dotblots and library-on-a-slide microarrays were more similar to a "gold standard" multigenephylogenetic tree than iga-conserved region hybridization or P6 7F3 epitope immunoblots.
Sandstedt
Sara A
SA
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109-2029, United States. sandsted@umich.edu
Zhang
Lixin
L
Patel
Mayurika
M
McCrea
Kirk W
KW
Qin
Zhaohui
Z
Marrs
Carl F
CF
Gilsdorf
Janet R
JR
D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry; D002353:Carrier State / Q000382:microbiology*; D002675:Child, Preschool; D000939:Epitopes / Q000032:analysis; D006190:Haemophilus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D018073:Haemophilus Vaccines / Q000737:chemistry; D006193:Haemophilus influenzae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D015151:Immunoblotting / Q000379:methods*; D009693:Nucleic Acid Hybridization / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D010614:Pharynx / Q000382:microbiology; D010802:Phylogeny; D012697:Serine Endopeptidases / Q000235:genetics*
D001425:Bacterial Outer Membrane Proteins; D000939:Epitopes; D018073:Haemophilus Vaccines; C069990:P6 outer membrane protein, Haemophilus; D012697:Serine Endopeptidases; C021433:IgA-specific serine endopeptidase