Remote control of cellular behaviour with magnetic nanoparticles.
By binding magnetic nanoparticles to the surface of cells, it is possible to manipulate and control cell function with an external magnetic field. The technique of activating cells with magnetic nanoparticles offers a means to isolate and explore cellular mechanics and ion channel activation to gain better understanding of these processes. Here, we go beyond using this technique as an investigative tool and focus on its potential to actively control cellular functions and processes with an eye towards biological and clinical applications. In particular, we focus on applications in tissue engineering and regenerative medicine.
Dobson
Jon
J
Institute for Science & Technology in Medicine, Keele University, Thornburrow Drive, Harsthill, Stoke-on-Trent, UK. bea22@keele.ac.uk
D002469:Cell Separation / Q000379:methods* / Q000639:trends; D018189:Immunomagnetic Separation / Q000379:methods / Q000639:trends*; D008846:Micromanipulation / Q000379:methods* / Q000639:trends; D053758:Nanoparticles / Q000627:therapeutic use*; D036103:Nanotechnology / Q000379:methods* / Q000639:trends; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends