title: Sequence of the spike protein of the Belgian B164S isolate of nephropathogenic infectious bronchitis virus.
abstract: The sequence of the gene encoding the spike glycoprotein (S) of the 1984 Belgian nephropathogenic isolate B1648 has been determined and shown to encode a protein of 1171 amino acids. Comparison of the deduced amino acid sequence of the S1 (amino-terminal half) of S, which induces virus-neutralizing antibodies, with that of vaccinal strains D274, H120 and D1466 revealed that it differed from them by 21, 25 and 49%, respectively, and by 24 to 25% from the North American nephropathogenic isolates Gray and Holte. The deduced amino add sequence of the S2 (carboxy-terminal) half of S differed by 10 to 12% (25% from D1466).
authors.affiliation: Compton Laboratory, Institute for Animal Health, Compton, Newbury, Berkshire, UK.
authors.forename: K
authors.initials: K
authors.lastname: Shaw
authors.forename: P
authors.initials: P
authors.lastname: Britton
authors.forename: D
authors.initials: D
authors.lastname: Cavanagh