title: A case report of metastasizing myoepithelial carcinoma of the parotid gland arising in a recurrent pleomorphic adenoma.
abstract: Myoepithelial carcinoma, arising in a recurrent or in a pre-existing pleomorphic adenoma of the parotid gland is an extremely rare cancer. We herein report the case of myoepithelial carcinoma occurring in a recurrent pleomorphic adenoma, which showed a high metastatic potential. A 53-year-old male, who had undergone a superficial parotidectomy of the pleomorphic adenoma 2 years previously, presented with recurrent parotid swelling and with multiple coin lesions in the lung. A total parotidectomy and a thoracoscopic biopsy of the lung lesion revealed both lesions to be myoepithelial carcinoma. The patient died about 12 months later despite undergoing intensive chemotherapy.
authors.affiliation: Department of Otorhinolaryngology, Juntendo University School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan. sooba@med.juntendo.ac.jp
authors.forename: Shinichi
authors.initials: S
authors.lastname: Ohba
authors.forename: Masato
authors.initials: M
authors.lastname: Fujimori
authors.forename: Shin
authors.initials: S
authors.lastname: Ito
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Matsumoto
authors.forename: Masateru
authors.initials: M
authors.lastname: Hata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takayanagi
authors.forename: Ryo
authors.initials: R
authors.lastname: Wada
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Ikeda
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010306:Parotid Gland / Q000601:surgery; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery; D003074:Solitary Pulmonary Nodule / Q000473:pathology / Q000556:secondary*