title: Fine-needle aspiration biopsy as an auxiliary diagnostic tool on intraoral minor salivary gland adenoid cystic carcinoma.
abstract: BACKGROUND
  Fine-needle aspiration biopsy (FNAB) is useful in diagnosis of major salivary gland adenoid cystic carcinoma (ACC), but it has been rarely reported on minor salivary gland ACC.
  
  
  OBJECTIVE
  The aim of this study was to report the utility of FNAB on diagnosis of ACC involving minor salivary glands.
  
  
  METHODS
  Three patients presenting ACC involving the palate (2 cases) and buccal mucosa (1 case), with a mean age of 36 years and 2:1 female-to-male ratio, were included in the study. All of the patients were submitted to FNAB for diagnostic purposes.
  
  
  RESULTS
  All smears were stained with hematoxylin-eosin, Papanicolaou, and Diff-Quik and showed the presence of small polyhedral cells with hyperchromatic nuclei and extracellular basophilic globular amorphous substance, compatible with ACC. Diagnosis of the 3 cases was subsequently confirmed through histopathology.
  
  
  CONCLUSIONS
  The FNAB was easy to perform and cost-effective, and proved to be an useful adjunctive tool in diagnosis of intraoral ACC.
authors.affiliation: Estacio de Sa University, Rio de Janeiro, Brazil.
authors.forename: Juliana de Noronha Santos
authors.initials: Jde N
authors.lastname: Netto
authors.forename: Aguida Maria Menezes Aguiar
authors.initials: AM
authors.lastname: Miranda
authors.forename: Henrique Martins
authors.initials: HM
authors.lastname: da Silveira
authors.forename: Teresa Cristina Ribeiro Bartholomeu
authors.initials: TC
authors.lastname: dos Santos
authors.forename: Fábio Ramôa
authors.initials: FR
authors.lastname: Pires
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle / Q000379:methods*; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002610:Cheek / Q000473:pathology; D004396:Coloring Agents; D003581:Cytodiagnosis / Q000379:methods; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005110:Extracellular Space; D005260:Female; D005456:Fluorescent Dyes; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D010157:Palatal Neoplasms / Q000473:pathology; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*
chemical_list: D004396:Coloring Agents; D005456:Fluorescent Dyes