title: [Results of autogenous bone marrow grafting in disorders of bone healing and bone defectives].
abstract: The aim of the study constituted a prospective assessment of efficacy of autogenous bone marrow grafting for the treatment of defective bone healing in patients with isolated and multiple injuries. Material comprised 3367 patients that were operated since June 1st 2004 to October 31st 2007 due to long bone fractures. Disorders of bone healing were diagnosed in 32 (0.95%) patients. 9 (28.1%) patients from the study group were treated due to multiple injuries (with severity of injuries assessed to be 33 points according to ISS; on the average 2.9 injured body regions). Multifragmental and comminutive fractures were note in 12 (37.5%), in this group 3 open fractures. The average time interval to achieve bone healing was 4.5 months, but was about twice longer in cases of pseudoarthrosis. The method was not effective in 7 (21.8%) patients. Defective bone healing was predominantly noted in cases of femoral, tibia and radial fractures. Bone marrow grafting proved the most effective in cases of delayed unions and non-infected pseudoarthrosis and non-union.
authors.affiliation: Klinika Medycyny Ratunkowej i Obrazeń Wielonarzadowych II Katedry Chirurgii UJ CM w Krakowie. whladki@interia.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Hładki
authors.forename: Jacek
authors.initials: J
authors.lastname: Lorkowski
authors.forename: Marek
authors.initials: M
authors.lastname: Trybus
authors.forename: Leszek
authors.initials: L
authors.lastname: Brongel
mesh_terms: D016026:Bone Marrow Transplantation; D005260:Female; D005592:Fracture Fixation / Q000009:adverse effects*; D017102:Fracture Healing; D050723:Fractures, Bone / Q000601:surgery*; D005597:Fractures, Open / Q000601:surgery*; D005599:Fractures, Ununited / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011542:Pseudarthrosis / Q000209:etiology / Q000601:surgery; D014182:Transplantation, Autologous; D016896:Treatment Outcome