title: Lung biopsy: special techniques.
abstract: Transthoracic needle biopsy of the indeterminate pulmonary nodule is a well-established, highly accurate, and minimally invasive diagnostic procedure. A pulmonary nodule in virtually any location is accessible to transthoracic needle biopsy. A solid understanding of special biopsy techniques enables the operator to overcome the commonly encountered challenges, including small, mobile, and partly obscured nodules. Because biopsy-related complications can be reduced but not completely eliminated, a familiarity with such complications and the procedures used to manage them is essential. A close partnership with the cytology team is crucial in achieving a high diagnostic accuracy during transthoracic needle biopsy. In the future, biopsy-derived microarray analysis may play a greater role in guiding treatment and predicting treatment outcomes.
authors.affiliation: Division of Chest Imaging, Department of Radiology, Weill Cornell Medical College, New York, New York 10065, USA. mac9166@med.cornell.edu
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Cham
authors.forename: Maureen E
authors.initials: ME
authors.lastname: Lane
authors.forename: Claudia I
authors.initials: CI
authors.lastname: Henschke
authors.forename: David F
authors.initials: DF
authors.lastname: Yankelevitz
mesh_terms: D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods*; D003581:Cytodiagnosis / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D010347:Patient Care Planning; D011187:Posture; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed