title: Salt-induced guest relocation from a macrocyclic cavity into a biomolecular pocket: interplay between cucurbit[7]uril and albumin.
abstract: The binding affinity of Neutral Red with cucurbit[7]uril (CB7) can be fine-tuned by addition and competitive binding of metal ions, which leads also to a pK(a) shift of the dye; this can be exploited to relocate the dye from the macrocyclic cavity of CB7 to the biomolecular pocket of bovine serum albumin.
authors.affiliation: Radiation & Photochemistry Division, Bhabha Atomic Research Centre, Mumbai, 400 085, India.
authors.forename: Mhejabeen
authors.initials: M
authors.lastname: Shaikh
authors.forename: Jyotirmayee
authors.initials: J
authors.lastname: Mohanty
authors.forename: Achikanath C
authors.initials: AC
authors.lastname: Bhasikuttan
authors.forename: Vanya D
authors.initials: VD
authors.lastname: Uzunova
authors.forename: Werner M
authors.initials: WM
authors.lastname: Nau
authors.forename: Haridas
authors.initials: H
authors.lastname: Pal
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D002417:Cattle; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry*; D009499:Neutral Red / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D001952:Bridged-Ring Compounds; D007093:Imidazoles; D009499:Neutral Red; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride; C456276:cucurbit(7)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils