Discovery of bifunctional thiourea/secondary-amine organocatalysts for the highly stereoselective nitro-Mannich reaction of alpha-substituted nitroacetates.
Han
Bo
B
Key laboratory of Drug-Targeting and Drug Deliver System of Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Liu
Qing-Ping
QP
Li
Rui
R
Tian
Xu
X
Xiong
Xiao-Feng
XF
Deng
Jin-Gen
JG
Chen
Ying-Chun
YC
D000085:Acetates / Q000138:chemical synthesis* / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D007097:Imines / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
D000085:Acetates; D000588:Amines; D004952:Esters; D007097:Imines; C028257:nitroacetic acid; D013890:Thiourea