title: Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica.
abstract: OBJECTIVE
  To determine the seroprevalence of neuromyelitis optica antibody (NMO)-IgG in Brazilian patients with clinical diagnosis of relapsing neuromyelitis optica, also known as Devic's disease.
  
  
  METHODS
  We determined NMO-IgG titers in 28 patients (25 of them females) that fulfilled the 1999 NMO diagnostic criteria proposed by Wingerchuk et al.
  
  
  RESULTS
  NMO-IgG was detected in 18 NMO patients (64.3%).
  
  
  CONCLUSIONS
  Our results showed that seroprevalence of NMO-IgG in Brazilian NMO patients was similar to the observed in other studies.
authors.affiliation: Department of Neurology, School of Medicine, University of São Paulo, São Paulo, SP, Brazil. tarso@dfvneuro.com.br
authors.forename: Tarso
authors.initials: T
authors.lastname: Adoni
authors.forename: Angelina Maria Martins
authors.initials: AM
authors.lastname: Lino
authors.forename: Paulo Eurípedes
authors.initials: PE
authors.lastname: Marchiori
authors.forename: Fernando
authors.initials: F
authors.lastname: Kok
authors.forename: Dagoberto
authors.initials: D
authors.lastname: Callegaro
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001938:Brazil; D002648:Child; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000276:immunology*; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D007074:Immunoglobulin G