title: Cu2O-catalyzed tandem ring-opening/coupling cyclization process for the synthesis of 2,3-dihydro-1,4-benzodioxins.
abstract: 2,3-Dihydro-1,4-benzodioxins can be prepared in a tandem one-pot procedure by reaction of o-iodophenols with epoxides catalyzed by Cu2O/1,10-phenanthroline/Cs2CO3 system. The reaction is suggested to occur via a novel ring-opening/coupling mechanism, giving moderate to good yields. Moreover, both aryl and aliphatic epoxides are tolerated under these conditions.
authors.affiliation: Department of Chemistry, Zhejiang University, Xi Xi Campus, Hangzhou, Zhejiang 310028, PR of China. wlbao@css.zju.edu.cn
authors.forename: Weiliang
authors.initials: W
authors.lastname: Bao
authors.forename: Yunyun
authors.initials: Y
authors.lastname: Liu
authors.forename: Xin
authors.initials: X
authors.lastname: Lv
authors.forename: Weixing
authors.initials: W
authors.lastname: Qian
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D004147:Dioxins / Q000138:chemical synthesis*; D004852:Epoxy Compounds / Q000737:chemistry; D010087:Oxides / Q000737:chemistry; D010618:Phenanthrolines / Q000737:chemistry
chemical_list: D004147:Dioxins; D004852:Epoxy Compounds; D010087:Oxides; D010618:Phenanthrolines; D003300:Copper