[Clinico-patogenetic value of glycated hemoglobin in therapeutic practice].
The purpose of the given job is to work out a new method of isoelectric focusing (IEF) of glicated haemoglobin. 747 patients have been observed. Glicated haemoglobin (Hba1c) was measured in 442 patients with diabetes mellitus and 305 patients without diabetes mellitus (DM) using basic methods: IEF with the following photocolorimetry (IEF+PC); photometric and chromatographic methods. The author modified IEF technique in borat-poliolnoj for definition of Hba1c in clinic. It was estimated analytical reliability of method IEF. It was established that methods of definition Hba1c are most used in laboratories. It was found a specified interrelation between the levels of Hba1c and consequences of DM.
Korolev
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D003920:Diabetes Mellitus / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007525:Isoelectric Focusing / Q000379:methods; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D006442:Glycated Hemoglobin