title: meso-Phbox-Pd(II) catalyzed tandem carbonylative cyclization of 1-ethynyl-1-propargyl acetate.
abstract: Palladium(II) catalyzed carbonylation of 1-ethynyl-1-propargyl acetate is described; in the absence of the bisoxazoline (box) ligand, the second triple bond did not react, affording cyclic orthoesters and . The use of meso-Phbox-Pd(ii) strikingly changed the course of the reaction, yielding bicyclic lactone by tandem carbonylative cyclization as a result of insertion of the second triple bond.
authors.affiliation: Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba, 274-8510, Japan. kkk@phar.toho-u.ac.jp
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kato
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Teraguchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Motodate
authors.forename: Akira
authors.initials: A
authors.lastname: Uchida
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Mochida
authors.forename: Tat'yana A
authors.initials: TA
authors.lastname: Peganova
authors.forename: Nikolai V
authors.initials: NV
authors.lastname: Vologdin
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Akita
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010293:Pargyline / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: C543581:1-ethynyl-1-propargyl acetate; D009942:Organometallic Compounds; D010165:Palladium; D010293:Pargyline