Wilms' tumor-1: a riddle wrapped in a mystery, inside a kidney.
After more than 15 years of intense study, WT1 remains a complex protein with multiple functions and targets. This Commentary discusses new developments and puts past results in perspective.
Kreidberg
Jordan A
JA
Department of Medicine, Children's Hospital Boston, Boston, Massachusetts 02115, USA. Jordan.Kreidberg@childrens.harvard.edu
Hartwig
Sunny
S
D000818:Animals; D006801:Humans; D007668:Kidney; D007680:Kidney Neoplasms / Q000235:genetics*; D051379:Mice; D018345:Mice, Knockout; D020033:Protein Isoforms; D025721:WT1 Proteins / Q000235:genetics*; D009396:Wilms Tumor / Q000235:genetics*
D020033:Protein Isoforms; D025721:WT1 Proteins