Depression and HIV/AIDS.
HIV/AIDS continues to be a significant public health problem. Millions of people worldwide are infected with this virus daily, and thousands die yearly of AIDS-related illnesses. Despite rapid advances in our knowledge about HIV and its mode of transmission, we have been unable to find a cure or prevent new infections. Psychiatric comorbidity is associated with HIV/AIDS: as a risk factor for HIV infection, a comorbidity of HIV infection, sequelae of HIV/AIDS, and a potential mediator for progression to AIDS. In this article, we focus on depression, which is prevalent in HIV/AIDS. We review the evidence associating depression with HIV, the challenges in recognizing depression in HIV-positive individuals, and the psychopharmacologic strategies known to be effective in the treatment of HIV-positive individuals with depression.
Benton
Tami D
TD
bentont@email.chop.edu
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000523:psychology*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D003865:Major Depressive Disorder / Q000188:drug therapy / Q000453:epidemiology*; D015658:HIV Infections / Q000453:epidemiology* / Q000523:psychology*; D006801:Humans; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
D000929:Antidepressive Agents, Tricyclic; D000697:Central Nervous System Stimulants; D017367:Selective Serotonin Reuptake Inhibitors