Mosquito-based transmission blocking vaccines for interrupting Plasmodium development.
Reduction of transmission is critical for effective malaria control. Transmission blocking vaccines, which are intended to prevent the parasites from infecting the mosquito vectors, could target mosquito antigens that are required for the successful development of the parasite in its vector. Here we review recent advances in the identification of promising candidate antigens for a mosquito-based transmission blocking vaccine.
Lavazec
Catherine
C
Institut Pasteur, Unité de génétique et génomique des insectes vecteurs, 28 rue du Docteur Roux, 75015 Paris, France. clavazec@pasteur.fr
Bourgouin
Catherine
C
D000818:Animals; D009033:Culicidae / Q000469:parasitology*; D006801:Humans; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission*; D017780:Malaria Vaccines / Q000276:immunology*; D010961:Plasmodium / Q000254:growth & development* / Q000276:immunology*
D017780:Malaria Vaccines