Four-component benzyne coupling reactions: a concise total synthesis of dehydroaltenuene B.
A four-component coupling reaction of 3,5-dimethoxybenzyne with 2-methyl-2-cyclohexenylmagnesium chloride, carbon dioxide, and iodine was utilized as a key step in the first total synthesis of dehydroaltenuene B.
Soorukram
Darunee
D
Department of Chemistry, Imperial College London, London SW7 2AZ, England.
Qu
Tao
T
Barrett
Anthony G M
AG
D001203:Ascomycota / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D053138:Cyclohexenes / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis*; D008274:Magnesium / Q000737:chemistry; D009183:Mycotoxins / Q000138:chemical synthesis; D009942:Organometallic Compounds / Q000737:chemistry
D001555:Benzene Derivatives; D053138:Cyclohexenes; D007783:Lactones; D009183:Mycotoxins; D009942:Organometallic Compounds; C524146:benzyne; C040005:altenuene; D008274:Magnesium