title: Bilateral ductal carcinoma in situ of the breast after radiation therapy for Ewing's sarcoma of the vertebra in a young woman: report of a case.
abstract: Thoracic radiation in the early years of life is a known risk factor for breast cancer later in life. A 21-year-old woman who had received thoracic radiation therapy for Ewing's sarcoma of the vertebra 9 years earlier was referred to our hospital for investigation of a palpable mass in her left breast. Ultrasonography and excisional biopsy showed ductal carcinoma in situ (DCIS) of the left breast, with no detectable pathology in the right breast except that it was more hypoplastic than the left breast. Considering the known risk factors for invasive breast cancer in both breasts, we performed bilateral skin-sparing mastectomy with immediate breast reconstruction using subpectoral implants. The final histopathological diagnosis was bilateral DCIS.
authors.affiliation: Fifth Department of Surgery, Ankara Numune Training and Research Hospital, Resat Nuri Sokak, No: 102/B-16, Yukari Ayranci, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Keskek
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kilic
authors.forename: Tamer
authors.initials: T
authors.lastname: Ertan
authors.forename: Adnan
authors.initials: A
authors.lastname: Erdem
authors.forename: Omer
authors.initials: O
authors.lastname: Yoldas
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000209:etiology* / Q000601:surgery; D002278:Carcinoma in Situ / Q000209:etiology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods; D009381:Neoplasms, Radiation-Induced / Q000601:surgery*; D012512:Sarcoma, Ewing / Q000532:radiotherapy*; D013125:Spinal Neoplasms / Q000532:radiotherapy*; D013904:Thoracic Vertebrae