title: Evidence of left ventricular systolic and diastolic dysfunction by color tissue Doppler imaging despite normal ejection fraction in patients on chronic hemodialysis program.
abstract: BACKGROUND
  Cardiovascular diseases are responsible for about half of deaths and are the major cause of mortality in hemodialysis patients. The aim of this study is to assess left ventricular (LV) longitudinal myocardial functions by color tissue Doppler imaging (TDI) in patients with chronic renal failure on a regular hemodialysis program.
  
  
  METHODS
  Thirty-one patients on a regular hemodialysis program (mean age 47 +/- 12 years; 17 males, 14 females) were included into the study. Twenty-three healthy subjects (mean age 44 +/- 8 years; 15 males, 8 females) were studied as a control group. The patients had been on maintenance hemodialysis for at least 1 month and hemodialysis sessions were three times per week. For color TDI, apical two- and four-chamber views of left ventricle were used. Sample volumes were placed on the mid-left ventricle in the inner half of the myocardium at the septum, lateral, inferior, and anterior walls. Peak LV strain, peak systolic strain rate, peak early diastolic strain rate, peak late diastolic strain rate, peak systolic tissue velocity, peak early diastolic tissue velocity, and peak late diastolic tissue velocity values were measured.
  
  
  RESULTS
  Mean peak LV strain, mean peak systolic strain rate, and mean peak systolic tissue velocity values were all lower in the hemodialysis group. Although mean peak late diastolic strain rate and mean peak late diastolic tissue velocity values were similar between the groups, mean peak early diastolic strain rate and mean peak early diastolic tissue velocity values were lower in the hemodialysis group.
  
  
  CONCLUSIONS
  Patients with chronic renal failure on regular hemodialysis program show significant alterations at LV longitudinal myocardial function parameters assessed by color TDI.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. okangulel@hotmail.com
authors.forename: Okan
authors.initials: O
authors.lastname: Gulel
authors.forename: Korhan
authors.initials: K
authors.lastname: Soylu
authors.forename: Serkan
authors.initials: S
authors.lastname: Yuksel
authors.forename: Muge
authors.initials: M
authors.lastname: Karaoglanoglu
authors.forename: Kuddusi
authors.initials: K
authors.lastname: Cengiz
authors.forename: Melda
authors.initials: M
authors.lastname: Dilek
authors.forename: Cavid
authors.initials: C
authors.lastname: Hamiseyev
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Kale
authors.forename: Nurol
authors.initials: N
authors.lastname: Arik
mesh_terms: D000328:Adult; D018618:Echocardiography, Doppler, Color / Q000379:methods*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000000981:diagnostic imaging* / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D006435:Renal Dialysis / Q000009:adverse effects*; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology*