title: Hair, nail, and pigment changes in major systemic disease.
abstract: In this article, the nail, hair, and pigment changes caused by systemic diseases will be reviewed. Among the subjects discussed are abnormalities of shape, attachments, surface, and color of the nails; hair alterations such as telogen and anagen effluvium, scarring alopecia, hypertrichosis, and hirsutism; and pigment changes due to connective tissue disorders, sarcoidosis, and metabolic and endocrinologic diseases, among others.
authors.affiliation: Sector of Dermatology and Post-Graduation Course, University Hospital and School of Medicine, Federal University of Rio de Janeiro, 22280-020 Rio de Janeiro, Brazil. ramos.e.silva@dermato.med.br
authors.forename: Marcia
authors.initials: M
authors.lastname: Ramos-e-Silva
authors.forename: Melissa
authors.initials: M
authors.lastname: Chaves Azevedo-e-Silva
authors.forename: Sueli Coclho
authors.initials: SC
authors.lastname: Carneiro
mesh_terms: D005260:Female; D006201:Hair Diseases / Q000209:etiology*; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000209:etiology*; D010859:Pigmentation Disorders / Q000209:etiology*