[Ovarian epithelial dysplasia: myth or reality? Review].
Ovarian epithelial dysplasia has been described in the ovarian surface epithelium by histologic, morphometric and nuclear profile studies. It could represent a potential precursor of ovarian malignancy in patients with genetic risk of ovarian cancer, although its natural history and progression to carcinoma are unpredictable. Diagnosis and identification of ovarian dysplasia would certainly be useful to understand the early steps of ovarian carcinogenesis. However, dysplasia in relation with ovulation induction seems to have a different pattern. We report dysplasia definitions and the current clinical management.
Chêne
G
G
Département de chirurgie, centre Jean-Perrin, rue Montalembert, 63000 Clermont-Ferrand, France. chenegautier@yahoo.fr
Penault-Llorca
F
F
Le Bouëdec
G
G
Mishellany
F
F
Dauplat
M-M
MM
Tardieu
A-S
AS
Pomel
C
C
Jaffeux
P
P
Aublet-Cuvelier
B
B
Pouly
J-L
JL
Déchelotte
P
P
Dauplat
J
J
D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D006801:Humans; D007150:Immunohistochemistry; D010049:Ovarian Diseases / Q000145:classification / Q000150:complications / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000235:genetics; D010060:Ovulation; D002578:Uterine Cervical Dysplasia / Q000145:classification / Q000150:complications / Q000473:pathology*