title: Superficial femoral artery thrombosis as a cause for distal embolism in primary antiphospholipid syndrome.
abstract: Antiphospholipid syndrome is a diagnosis with the clinical manifestations of thromboses in the presence of an antiphospholipid antibody. A 25-year-old man with a history of deep venous thrombosis, pulmonary emboli, and myocardial infarction, and receiving long-term anticoagulation with warfarin, all due to primary antiphospholipid syndrome, presented with blue toe syndrome from a primary superficial femoral artery thrombus. He was anticoagulated with fondaparinux in addition to dipyridamole and aspirin perioperatively. The area of thrombus was resected and reconstructed using a cephalic vein interposition graft. This report reviews antiphospholipid syndrome and identifies potential questions and problems relating to a rare clinical presentation.
authors.affiliation: University of Arizona Health Science Center and Southern Arizona Veterans Affairs Health Care System, Tucson, Ariz, USA.
authors.forename: Lannery S
authors.initials: LS
authors.lastname: Lauvao
authors.forename: Kaoru R
authors.initials: KR
authors.lastname: Goshima
authors.forename: Luis R
authors.initials: LR
authors.lastname: Leon
authors.forename: Paul E
authors.initials: PE
authors.lastname: Nolan
authors.forename: John D
authors.initials: JD
authors.lastname: Hughes
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001157:Arterial Occlusive Diseases / Q000150:complications* / Q000175:diagnosis; D018438:Blue Toe Syndrome / Q000209:etiology* / Q000628:therapy; D005263:Femoral Artery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D017131:Thrombectomy / Q000379:methods*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D014859:Warfarin