title: A histone code for chromatin assembly.
abstract: In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. (2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histone chaperones CAF-1 and Rtt106. Chen et al. (2008) establish that the acetylation mark promotes chromatin reassembly following DNA double-strand break repair.
authors.affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Fillingham
authors.forename: Jack F
authors.initials: JF
authors.lastname: Greenblatt
mesh_terms: D000107:Acetylation; D042002:Chromatin Assembly and Disassembly; D053903:DNA Breaks, Double-Stranded; D004260:DNA Repair; D042421:Histone Code; D006657:Histones / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000378:metabolism*
chemical_list: D006657:Histones