[The effect of gengnianningshentang on treating 72 patients with female climacteric syndrome of fever due to yin-deficiency].
OBJECTIVE
To observe the clinical effect of gengnianningshentang on the treatment of the climacteric syndrome of fever due to yin-deficiency.


METHODS
108 patients with climacteric syndrome of fever due to yin-deficiency were divided randomly into treatment group (76 cases)and control group (32 cases). Treatment group was treated by gengnianningshentang, and control group was treated by Vitamin E for 3 months. Level of serum E2, LH and FSH were determined, while the variation of symptom scores of climacteric syndrome was observed.


RESULTS
Level of serum E2 in treatment group increased significantly and serum LH and FSH decreased significantly after treatment (p < 0.01). The post treatment total scores of climacteric syndrome in the treament group were significantly improved (p < 0.01).


CONCLUSIONS
Gengnianningshentang can significantly improve the levels of E2, FSH and LH, and climacteric syndrome in patients of fever due to yin-deficiency. The total effect of gengnianningshentang is much better than western medicine.
Li
Jian-Jun
JJ
Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China.
Pan
Ai-Zhen
AZ
Yi
Wei-Min
WM
D002979:Climacteric; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D019584:Hot Flashes / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D016896:Treatment Outcome; D014810:Vitamin E / Q000494:pharmacology / Q000627:therapeutic use; D016710:Yin Deficiency / Q000097:blood / Q000188:drug therapy
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D014810:Vitamin E; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone