The isoelectric point, a key to understanding a variety of biochemical problems: a minireview.
We address the importance of the isoelectric point (IEP) of proteins and membrane components such as phospholipids for our understanding and interpretation of isoforms and opposite charge interactions in the formation of complexes. Five examples drawn from the literature are newly approached from the IEP point of view to clarify general principles.
Schuurmans Stekhoven
F M A H
FM
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, Nijmegen, 6525 ED, The Netherlands. F.Stekhoven@science.ru.nl
Gorissen
M H A G
MH
Flik
G
G
D000818:Animals; D001669:Biochemical Phenomena; D001671:Biochemistry; D006801:Humans; D007526:Isoelectric Point; D010743:Phospholipids / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*
D010743:Phospholipids; D011506:Proteins