title: [Organ-specific fungal infections as a complication of treatment of children with cancer. A single centre observation].
abstract: Increasing intensity of treatment of childhood malignancies as well as administration of the new generation broad-spectrum antibiotics is associated with increased risk of fungal infections. In this paper, we describe two patients, in whom anti-neoplastic treatment was complicated by systemic fungal infection. Early suspicion and/or detection of fungal infection enables more effective and shorter treatment. Administration of an anti-fungal drug should be considered in every neutropenic patient after chemotherapy and/or with protracted fever. Since the anti-fungal treatment is usually prolonged, this results in significant interruption of the chemotherapy.
authors.affiliation: Katedra i Klinika Pediatrii, Hematologii i Onkologii Dzieciecej, Slaska Akademia Medyczna, ul. 3 Maja 13/15, 41-800 Zabrze, Poland.
authors.forename: Lidia
authors.initials: L
authors.lastname: Kajdas
authors.forename: Tomasz
authors.initials: T
authors.lastname: Szczepański
authors.forename: Sylwia
authors.initials: S
authors.lastname: Trzeszkowska-Rotkegel
authors.forename: Halina
authors.initials: H
authors.lastname: Bubała
authors.forename: Danuta
authors.initials: D
authors.lastname: Sońta-Jakimczyk
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D009181:Mycoses / Q000209:etiology*; D009369:Neoplasms / Q000150:complications*; D009503:Neutropenia / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents