Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica.
OBJECTIVE
To determine the seroprevalence of neuromyelitis optica antibody (NMO)-IgG in Brazilian patients with clinical diagnosis of relapsing neuromyelitis optica, also known as Devic's disease.


METHODS
We determined NMO-IgG titers in 28 patients (25 of them females) that fulfilled the 1999 NMO diagnostic criteria proposed by Wingerchuk et al.


RESULTS
NMO-IgG was detected in 18 NMO patients (64.3%).


CONCLUSIONS
Our results showed that seroprevalence of NMO-IgG in Brazilian NMO patients was similar to the observed in other studies.
Adoni
Tarso
T
Department of Neurology, School of Medicine, University of São Paulo, São Paulo, SP, Brazil. tarso@dfvneuro.com.br
Lino
Angelina Maria Martins
AM
Marchiori
Paulo Eurípedes
PE
Kok
Fernando
F
Callegaro
Dagoberto
D
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001938:Brazil; D002648:Child; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000276:immunology*; D016036:Seroepidemiologic Studies; D055815:Young Adult
D001323:Autoantibodies; D015415:Biomarkers; D007074:Immunoglobulin G