[Combined treatment for rectal cancer using different radiomodification means].
The paper presents an evaluation of the results of surgical and combined treatment received by 961 patients at the Center's Clinics within 28 years. The analysis was based on 3 protocols of prospective randomized study. It dealt with assessment of the end results of surgical and combined treatment for operable rectal cancer using one preoperative hyperfractonated STD of 5-25 Gy. That was combined with local microwave hyperthermia and two radio modifiers--local microwave hyperthermia+intrarectal administration of a preparation containing metronidazolum. Due to the latter factor, the rate of 3-year relapse-free survival rose considerably. Also, loco-regional and distant metastasis incidence was cut down due to superior ablasticity of surgery.
Barsukov
Iu A
IuA
Tkachev
S I
SI
Oltarzhevskaia
N D
ND
Korovina
M A
MA
Iarmolenko
S P
SP
Vaĭnson
A A
AA
Perevoshchikov
A G
AG
Nikolaev
A V
AV
Gradiushko
A T
AT
Kutateladze
T O
TO
Vlasov
O A
OA
Malikho
A G
AG
Tamrazov
R I
RI
Kuz'michev
D V
DV
Aliev
V A
VA
Mamedli
Z Z
ZZ
D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012004:Rectal Neoplasms / Q000401:mortality* / Q000628:therapy*; D012189:Retrospective Studies; D015996:Survival Rate