title: Contrast-enhanced sonography of a hepatocellular carcinoma undergoing spontaneous necrosis.
abstract: Spontaneous necrosis of hepatocellular carcinoma (HCC) is rare. We report the case of a 72-year-old woman with an HCC nodule that underwent necrosis after sonographically guided needle biopsy. Baseline sonographic examination revealed only a nonspecific change in the echogenicity of the lesion. Subsequent necrosis was suggested on contrast-enhanced sonographic examination and was confirmed on spiral CT.
authors.affiliation: Department of Gastroenterology, Misericordia Hospital, Via Senese 22, 58100 Grosseto, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Giannetti
authors.forename: Marco
authors.initials: M
authors.lastname: Corsetti
authors.forename: Sergio
authors.initials: S
authors.lastname: Quaranta
authors.forename: Luca
authors.initials: L
authors.lastname: Franci
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D009336:Necrosis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D010743:Phospholipids; D013459:Sulfur Hexafluoride; D036542:Tomography, Spiral Computed; D018084:Ultrasonography, Interventional
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride