title: Value of the intraoperative assessment of the depth of myometrial invasion in endometrial carcinoma.
abstract: OBJECTIVE
  The aim of the study was to evaluate the value of intraoperative assessment of depth of myometrial invasion in patients with FIGO stage I of the endometrial carcinoma.
  
  
  METHODS
  A total number of 112 patients with FIGO stage I of the endometrial carcinoma undergoing surgery were enrolled in the study. All patients had undergone intraoperative assessment of the depth of myometrial invasion performed by a surgeon. The depth was determined as more or less than 50% of myometrial thickness according to FIGO classification. Gross visual estimation of the depth of myometrial invasion at the time of the operation was compared with the final histopathological report. Sensitivity, specificity and positive and negative predictive values of the method were determined by means of statistical analyses.
  
  
  RESULTS
  The depth of the myometrial invasion was accurately determined by the surgeon in 82.1% of cases. Sensitivity and specificity were 68% and 82.1%, respectively. The accurate prediction rate of the myometrial invasion in the group of patients with well differentiated (G1) endometrial carcinoma was higher (88.4%) than in group with moderately and low differentiated tumour (78.3%).
  
  
  CONCLUSIONS
  The accuracy of macroscopic evaluation of myometrial invasion is high and reaches up to 82.1%. The accurate determination rate increases if the differentiation of tumour is higher.
authors.affiliation: Institute of Nursing and Obstetrics, Faculty of Medicine, University of Rzeszów. b.obrzut@interia.pl
authors.forename: Bogdan
authors.initials: B
authors.lastname: Obrzut
authors.forename: Marzanna
authors.initials: M
authors.lastname: Obrzut
authors.forename: Joanna
authors.initials: J
authors.lastname: Skret-Magierło
authors.forename: Andrzej
authors.initials: A
authors.lastname: Skret
authors.forename: Dariusz
authors.initials: D
authors.lastname: Ulman
authors.forename: Piotr
authors.initials: P
authors.lastname: Król
authors.forename: Marcin
authors.initials: M
authors.lastname: Zmuda
mesh_terms: D000328:Adult; D000368:Aged; D018269:Carcinoma, Endometrioid / Q000473:pathology* / Q000601:surgery*; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011044:Poland; D011237:Predictive Value of Tests; D011446:Prospective Studies