title: [Cushing's syndrome].
abstract: Cushing's syndrome results from inappropriate exposure to excessive endogenous glucocorticoids. Untreated, it has an important morbidity and a significant mortality. The syndrome remains a challenge to diagnose and manage. Here, we propose algorithms for the diagnosis of Cushing's syndrome and its cause, and review pathogenesis, clinical features, and treatment.
authors.affiliation: Centre de référence maladies rares de la surrénale, service des maladies endocriniennes et métaboliques, hôpital Cochin, AP-HP 75679 Paris.
authors.forename: Laurence
authors.initials: L
authors.lastname: Guignat
authors.forename: Xavier
authors.initials: X
authors.lastname: Bertagna
authors.forename: Jérôme
authors.initials: J
authors.lastname: Bertherat
mesh_terms: D003480:Cushing Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D003937:Diagnosis, Differential; D006801:Humans