title: BFA effects are tissue and not just plant specific.
abstract: Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified.
authors.affiliation: Department of Cell Biology, Heidelberg Institute for Plant Sciences, University of Heidelberg, 69120 Heidelberg, Germany.
authors.forename: David G
authors.initials: DG
authors.lastname: Robinson
authors.forename: Markus
authors.initials: M
authors.lastname: Langhans
authors.forename: Claude
authors.initials: C
authors.lastname: Saint-Jore-Dupas
authors.forename: Chris
authors.initials: C
authors.lastname: Hawes
mesh_terms: D020126:Brefeldin A / Q000494:pharmacology*; D006056:Golgi Apparatus / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D018546:Hypocotyl / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D018515:Plant Leaves / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D010944:Plants / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D020126:Brefeldin A