title: Group efficiency: a guideline for hits-to-leads chemistry.
authors.affiliation: Astex Therapeutics Ltd., 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK. m.verdonk@astex-therapeutics.com
authors.forename: Marcel L
authors.initials: ML
authors.lastname: Verdonk
authors.forename: David C
authors.initials: DC
authors.lastname: Rees
mesh_terms: D002626:Chemistry, Pharmaceutical; D004353:Drug Evaluation, Preclinical; D017408:Guidelines as Topic; D013816:Thermodynamics