Reducing oxidized lipids to prevent cardiovascular disease.
Despite significant success in reducing plasma cholesterol, especially low-density lipoprotein cholesterol, risks for cardiovascular disease (CVD) complications remain. Among these risks are circulating levels of oxidative modified lipoproteins, primarily oxidized low-density lipoproteins (oxLDL). The evidence supporting oxLDL as a potential target for therapeutic management to reduce metabolic complications and CVD events is reviewed in this report.
Le
Ngoc-Anh
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Emory Lipid Research Laboratory, Emory University and Atlanta Veterans' Affairs Medical Center, 1670 Clairmont Road, Room 4A187, Decatur, GA 30033, USA. ale@emory.edu