[Effects of Qiulirunfei extracta on immunological function and influenza virus in mice].
OBJECTIVE
To investigate the effect of Qiulirunfei extracta on immunological function and Influenza virus type A (FM1 strain) in ICR mice.


METHODS
After given Qiulirunfei extracta, mice's body weight, spleen weight and lymphocyte stimulation index (SI) were tested; its antiviral effect was also observed in mice and chick embryo.


RESULTS
Qiulirunfei extracta inhibited effectively the growth of influenza virus type A (FM1 strain) in chick embryo, and reduced the mortality rate of mice infected by influenza virus type A (FM1 strain). Compared with control group, body weight, spleen index in experiment group increased greatly, and SI of lymphocyte increased significantly too.


CONCLUSIONS
Qiulirunfei extracta shows antiviral effects, and it is a good immune system enhancer.
Li
Xia
X
Department of Microbiology of Tianjin Medical University, Tianjin 300070, China.
Li
Xiao-Mian
XM
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D002642:Chick Embryo; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D009980:Influenza A virus / Q000187:drug effects*; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009976:Orthomyxoviridae Infections / Q000473:pathology / Q000517:prevention & control*; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D015996:Survival Rate; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D000998:Antiviral Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal