The rat temporal association cortical area 2 (Te2) comprises two subdivisions that are visually responsive and develop independently.
In this study, we have used the expression of non-phosphorylated neurofilament (NNF), a protein that exhibits differential areal and laminar neuronal patterning, to assess the chemoarchitectural organization of the rat temporal association cortex (Te). Since expression of NNF is associated with the latter stages of neuronal development, this enabled us to profile the hierarchical development of this region of the cortex. We also examined the expression of the protein Fos, the product of the immediate-early gene cFos, as a neuronal activity marker to determine which areas within this region are visually responsive. Our findings reveal the existence of two previously undescribed subdivisions within the dorsal and ventral domains of the rat temporal association cortical area 2 (Te2) which we have termed Te2d and Te2v, respectively. We also demonstrated the early maturation of the caudal region of Te2d while preceding the primary visual cortex. Within this region of the cortex, the Fos protein indicates that both subdivisions are visually responsive.
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Department of Anatomy and Cell Biology, Monash University, Clayton, Victoria, 3800, Australia.
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D000375:Aging / Q000502:physiology*; D000818:Animals; D005075:Biological Evolution; D001931:Brain Mapping; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D016900:Neurofilament Proteins / Q000378:metabolism; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D010775:Photic Stimulation; D011323:Primates / Q000033:anatomy & histology / Q000502:physiology; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D051381:Rats; D013045:Species Specificity; D013702:Temporal Lobe / Q000033:anatomy & histology* / Q000254:growth & development* / Q000378:metabolism; D014793:Visual Cortex / Q000033:anatomy & histology* / Q000254:growth & development* / Q000378:metabolism; D014796:Visual Perception / Q000502:physiology*
D016900:Neurofilament Proteins; D016760:Proto-Oncogene Proteins c-fos