Natural marine anti-inflammatory products.
The marine environment has been shown to be the source of a great diversity of chemical structures with promising biological activities. The isolation, biological evaluation, chemical properties and synthetic elaborations of the products of marine organisms and microorganisms have attracted the attention of organic chemists, medicinal chemists, biologists and pharmacists. Marine organisms and microorganisms have provided a large proportion of the natural anti-inflammatory products over the last years. Marine organisms include green algae, brown algae, red algae, sponges, coelenterates, bryozoans, molluscs, tunicates, echinoderms, miscellaneous marine organisms and marine microorganisms and phytoplankton. This review describes current progress in the development of a selection of new anti-inflammatory agents from marine sources. The chemistry and biological evaluation are discussed.
Abad
María José
MJ
Department of Pharmacology, Faculty of Pharmacy, University Complutense, Ciudad Universitaria s/n, 28040, Madrid, Spain. mjabad@farm.ucm.es
Bedoya
Luis Miguel
LM
Bermejo
Paulina
P
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry*; D006801:Humans; D006838:Hydrocarbons / Q000737:chemistry; D008386:Marine Biology; D011134:Polysaccharides / Q000737:chemistry
D000893:Anti-Inflammatory Agents; D001688:Biological Products; D006838:Hydrocarbons; D011134:Polysaccharides