[Studies on chemical constituents of the roots of Angelica pubescens].
OBJECTIVE
To study the chemical constituents of the roots of Angelica pubescens.


METHODS
Fresh roots of Angelica pubescens were extracted with EtOH,the chemical constituents in the extract were isolated by column chromatography as macroporous absorption resin,and ODS etc. Their structures were confirmed by spectral analysis (NMR, MS).


RESULTS
Seven compounds were isolated and their structures were identified as nodakenetin (I), umbelliferone (II), columbianetin (III), beta-D-glucosyl-columbianetin (IV), columbianin (V), tert. -O-beta-D- glucopyranosyl -(R)-by-akangelicin (VI) and sec. -O-beta-D- glucopyranosyl-(R) -byakangelicin (VII).


CONCLUSIONS
Compound IV, VI and VII are isolated from Angelica pubescens for the first time.
Ding
Xi-Fei
XF
Jiangsu Institute of Botany, CAS, Nanjing Botanical Garden Mem Sun Yat-Sen, Nanjing 210014, China.
Feng
Xu
X
Dong
Yun-Fa
YF
Zhao
Xing-Zeng
XZ
Chen
Yu
Y
Wang
Ming
M
D000157:Aconitine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D029969:Angelica / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014468:Umbelliferones / Q000737:chemistry / Q000302:isolation & purification*
C457321:8-O-methylcolumbianine; D003374:Coumarins; D011564:Furocoumarins; D005960:Glucosides; D014468:Umbelliferones; C062747:columbianetin glucopyranoside; C031477:7-hydroxycoumarin; C001684:marmesin; D000157:Aconitine