Convergent total syntheses of fluvibactin and vibriobactin using molybdenum(VI) oxide-catalyzed dehydrative cyclization as a key step.
Efficient total syntheses of fluvibactin and vibriobactin have been achieved via molybdenum(VI) oxide-catalyzed dehydrative cyclization, Sb(OEt)(3)-catalyzed ester-amide transformation, and WSCI and HOAt-promoted dehydrative amide formation.
Sakakura
Akira
A
EcoTopia Science Institute, Nagoya University, Japan.
Umemura
Shuhei
S
Ishihara
Kazuaki
K
D002384:Catalysis; D002396:Catechols / Q000138:chemical synthesis*; D003500:Cyclization; D008982:Molybdenum / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis*; D013095:Spermidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D014867:Water / Q000737:chemistry*
D002396:Catechols; D010080:Oxazoles; D014867:Water; C082368:fluvibactin; D008982:Molybdenum; C040227:vibriobactin; C024687:sodium molybdate(VI); D013095:Spermidine