[Therapeutic or prophylactic antifungal vaccination: problems and solutions].
Due to a growing number of immunosuppressed patients after organ transplantation or antineoplastic chemotherapy, the significance of fungal infections has increased worldwide. In the future a large number of clinical studies with regard to genetically engineered vaccines - based on already performed pre-clinical investigations - will be conducted. However, classic vaccines might be of limited efficacy in fungal infections since fungi elicit primarily cellular immune responses.
Boneberger
S
S
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum Innenstadt, Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, 80337, München, Deutschland. Susanne.Boneberger@med.uni-muenchen.de
Korting
H C
HC
D003881:Dermatomycoses / Q000188:drug therapy* / Q000517:prevention & control*; D005657:Fungal Vaccines / Q000627:therapeutic use*; D006801:Humans; D014611:Vaccination / Q000379:methods*
D005657:Fungal Vaccines