Acute disseminated encephalomyelitis: clinical and pathogenesis features.
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADEM reveals involvement of white matter, with infiltration of monocytoid cells and perivenous demyelination.
Noorbakhsh
Farshid
F
Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.
Johnson
Richard T
RT
Emery
Derek
D
Power
Christopher
C
D003937:Diagnosis, Differential; D004673:Encephalomyelitis, Acute Disseminated / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D006801:Humans; D007114:Immunization; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D014765:Viral Vaccines / Q000008:administration & dosage
D014765:Viral Vaccines