title: A novel placement method of the Bravo wireless pH monitoring capsule for measuring intragastric pH.
abstract: OBJECTIVE
  The delivery system of the Bravo capsule was designed for placement on the esophagus. We evaluated the feasibility of our novel placement method of the Bravo capsule using a clip to monitor intragastric pH and to compare the accuracy of the Bravo wireless system to the traditionally used Slimline catheter-Mark III Digitrapper pH monitoring system.
  
  
  METHODS
  The Bravo capsule was placed by clip or conventional delivery system using suction on the gastric wall in 20 fasted subjects. A separate group of ten healthy volunteers underwent simultaneous intragastric pH monitoring for comparison of the two systems with meals.
  
  
  RESULTS
  Early dislodgment rate of the capsules was lower when placed using clipping (20%) than using conventional delivery system (70%) within 48 h after placement. We observed prominent movement of one catheter in the stomach during the study. Post-test calibration drifts of the catheters at pH 7.01 were significantly greater than those of the Bravo capsules (P = 0.02).
  
  
  CONCLUSIONS
  Our novel clipping method of the Bravo pH capsule placement provided accurate monitoring of intragastric pH with merits of tolerability, acid stability, and fixing position.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kangnam St. Mary's Hospital, The Catholic University of Korea, No. 505, Banpo-Dong, Seocho-Gu, Seoul, 137-040, South Korea.
authors.forename: Jae Hyuck
authors.initials: JH
authors.lastname: Chang
authors.forename: Myung Gyu
authors.initials: MG
authors.lastname: Choi
authors.forename: Dong-Seok
authors.initials: DS
authors.lastname: Yim
authors.forename: Yu Kyung
authors.initials: YK
authors.lastname: Cho
authors.forename: Jae Myung
authors.initials: JM
authors.lastname: Park
authors.forename: In Seok
authors.initials: IS
authors.lastname: Lee
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Kim
authors.forename: In Sik
authors.initials: IS
authors.lastname: Chung
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization; D050782:Esophageal pH Monitoring; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D013270:Stomach / Q000737:chemistry; D055815:Young Adult