Highly diastereoselective and enantioselective formal [4 + 1] ylide annulation for the synthesis of optically active dihydrofurans.
On the basis of the reactions of camphor-derived sulfur ylide with alpha-ylidene-beta-diketones, highly efficient and selective synthesis of optically active dihydrofurans has been achieved.
Zheng
Jun-Cheng
JC
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Orangic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Zhu
Chun-Yin
CY
Sun
Xiu-Li
XL
Tang
Yong
Y
Dai
Li-Xin
LX