Coexistence of tumid lupus erythematosus with systemic lupus erythematosus and discoid lupus erythematosus: a report of two cases of tumid lupus.
Tumid lupus erythematosus (LE) is a rare variant of chronic cutaneous LE that is characterized clinically by smooth, nonscarring, pink to violaceous papules or plaques without evidence of surface change. Histopathologic features include superficial and deep lymphocytic infiltration in a perivascular and periadnexal distribution, with dermal interstitial mucin deposition and focal or absent dermoepidermal junction involvement. These clinical and histopathologic features can be challenging to differentiate from other cutaneous diseases. This is particularly true because patients with tumid LE usually do not have other manifestations of systemic LE or cutaneous LE. We present 2 cases of tumid LE, one associated with concomitant systemic LE and the other occurring concurrently with discoid LE. Furthermore, we demonstrate the rare occurrence of a patient with tumid LE occurring below the waist at a photo-protected site.
Stead
Jennifer
J
Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
Headley
Catherine
C
Ioffreda
Michael
M
Kovarik
Carrie
C
Werth
Victoria
V
D000328:Adult; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D012867:Skin / Q000473:pathology