Fine-needle aspiration biopsy as an auxiliary diagnostic tool on intraoral minor salivary gland adenoid cystic carcinoma.
BACKGROUND
Fine-needle aspiration biopsy (FNAB) is useful in diagnosis of major salivary gland adenoid cystic carcinoma (ACC), but it has been rarely reported on minor salivary gland ACC.


OBJECTIVE
The aim of this study was to report the utility of FNAB on diagnosis of ACC involving minor salivary glands.


METHODS
Three patients presenting ACC involving the palate (2 cases) and buccal mucosa (1 case), with a mean age of 36 years and 2:1 female-to-male ratio, were included in the study. All of the patients were submitted to FNAB for diagnostic purposes.


RESULTS
All smears were stained with hematoxylin-eosin, Papanicolaou, and Diff-Quik and showed the presence of small polyhedral cells with hyperchromatic nuclei and extracellular basophilic globular amorphous substance, compatible with ACC. Diagnosis of the 3 cases was subsequently confirmed through histopathology.


CONCLUSIONS
The FNAB was easy to perform and cost-effective, and proved to be an useful adjunctive tool in diagnosis of intraoral ACC.
Netto
Juliana de Noronha Santos
Jde N
Estacio de Sa University, Rio de Janeiro, Brazil.
Miranda
Aguida Maria Menezes Aguiar
AM
da Silveira
Henrique Martins
HM
dos Santos
Teresa Cristina Ribeiro Bartholomeu
TC
Pires
Fábio Ramôa
FR
D000328:Adult; D044963:Biopsy, Fine-Needle / Q000379:methods*; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002610:Cheek / Q000473:pathology; D004396:Coloring Agents; D003581:Cytodiagnosis / Q000379:methods; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005110:Extracellular Space; D005260:Female; D005456:Fluorescent Dyes; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D010157:Palatal Neoplasms / Q000473:pathology; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*
D004396:Coloring Agents; D005456:Fluorescent Dyes