Stuttering priapism complicating warfarin therapy in a patient with protein C deficiency.
Priapism is a rare disorder defined as a persistent penile erection that continues hours beyond, or is unrelated to, sexual stimulation. There are two types of priapism; ischemic low-flow type or non-ischemic high flow, with differing etiologies. Priapism associated with thrombophilia is a well-recognized entity. However, the pathogenesis of this association is not fully understood. We report a rare case of recurrent (stuttering) priapism in a patient with protein C deficiency while maintained on Warfarin therapy. This therapy was also complicated by Warfarin-induced skin necrosis.
Abu Sham'a
R A H
RA
Department of Internal Medicine and Cardiology, Makassed Hospital, Jerusalem, Israel. dr_rshama@yahoo.com
Kufri
F H
FH
Yassin
I H
IH
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D017984:Enoxaparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011317:Priapism / Q000209:etiology*; D020151:Protein C Deficiency / Q000150:complications / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000209:etiology; D020246:Venous Thrombosis / Q000150:complications* / Q000209:etiology; D014859:Warfarin / Q000009:adverse effects* / Q000627:therapeutic use
D000925:Anticoagulants; D017984:Enoxaparin; D014859:Warfarin