title: [Predictive value of serum PSA in detection of prostate cancer by fine needle biopsy].
abstract: Parallel study of PSA and needle biopsy were performed in 356 men, aged 42-92 years; prostate cancer was detected in 182 cases while no cancer--in 174. When PSA level ranged 4-20 ng/ml, at density of 0.1-0.3, its specificity was low and cancer detection was under 50%. There was a direct correlation between the PSA indices and cancer detection rate, and nearly 100% of tumors were detected at the values of 25-30 ng/ml and 0.5-0.9 respectively. PSA level and especially results of morphological examination by means of prostate needle biopsy (Gleason) offer possibility to visualize tumor size and its malignant potential.
authors.forename: K M
authors.initials: KM
authors.lastname: Pozharisskiĭ
authors.forename: A A
authors.initials: AA
authors.lastname: Arzumanov
authors.forename: A G
authors.initials: AG
authors.lastname: Kudaĭbergenova
authors.forename: I V
authors.initials: IV
authors.lastname: Ovchinnikov
authors.forename: R V
authors.initials: RV
authors.lastname: Leonenkov
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology*; D012680:Sensitivity and Specificity
chemical_list: D017430:Prostate-Specific Antigen