Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study.
Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population.


OBJECTIVE
to study the impact of amoxicillin for 7 days in post-adenotonsillectomy recovery, comparing results with a control group.


METHODS
prospective, randomized, controlled study with 120 patients.


METHODS
the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities.


RESULTS
It was only in the fourth post-operative day that the group receiving antibiotic agents showed a statistically significant difference as far as pain is concerned. There was no difference between the two groups for other data analyzed.


CONCLUSIONS
considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.
Guerra
Marja Michelin
MM
FMABC, Brazil.
Garcia
Eduardo
E
Pilan
Renata Ribeiro de Mendonça
RR
Rapoport
Priscila Bogar
PB
Campanholo
Caio Barbosa
CB
Martinelli
Eli Onivaldo
EO
D000082:Acetaminophen / Q000627:therapeutic use; D000658:Amoxicillin / Q000009:adverse effects / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D004177:Dipyrone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005334:Fever / Q000517:prevention & control; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D014068:Tonsillectomy
D018712:Analgesics, Non-Narcotic; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen; D004177:Dipyrone; D000658:Amoxicillin