title: Detection of cement leakage after vertebroplasty with a non-flat-panel angio unit compared to multidetector computed tomography--an ex vivo study.
abstract: The purpose of this study was to investigate the detection of cement leakages after vertebroplasty using angiographic computed tomography (ACT) in a non-flat-panel angio unit compared to multidetector computed tomography (MDCT). Vertebroplasty was performed in 19 of 33 cadaver vertebrae (23 thoracic and 10 lumbar segments). In the angio suite, ACT (190 degrees ; 1.5 degrees per image) was performed to obtain volumetric data. Another volumetric data set of the specimen was obtained by MDCT using a standard algorithm. Nine multiplanar reconstructions in standardized axial, coronal, and sagittal planes of every vertebra were generated from both data sets. Images were evaluated on the basis of a nominal scale with 18 criteria, comprising osseous properties (e.g., integrity of the end plate) and cement distribution (e.g., presence of intraspinal cement). MDCT images were regarded as gold standard and analyzed by two readers in a consensus mode. Rotational acquisitions were analyzed by six blinded readers. Results were correlated with the gold standard using Cohen's j-coefficient analysis. Furthermore, interobserver variability was calculated. Correlation with the gold standard ranged from no correlation (osseous margins of the neuroforamen, j = 0.008) to intermediate (trace of vertebroplasty canula; j = 0.615) for criteria referring to osseous morphology. However, there was an excellent correlation for those criteria referring to cement distribution, with kappa values ranging from 0.948 (paravertebral cement distribution) to 0.972 (intraspinal cement distribution). With a minimum of j = 0.768 ("good correlation") and a maximum of j = 0.91 ("excellent"), interobserver variability was low. In conclusion, ACT in an angio suite without a flat-panel detector depicts a cement leakage after vertebroplasty as well as MDCT. However, the method does not provide sufficient depiction of osseous morphology.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum Ernst von, Bergmann gGmbH, Charlottenstr. 72, 14467 Potsdam, Germany. clebaumann@yahoo.com
authors.forename: Clemens
authors.initials: C
authors.lastname: Baumann
authors.forename: Heiko
authors.initials: H
authors.lastname: Fuchs
authors.forename: Kerstin
authors.initials: K
authors.lastname: Westphalen
authors.forename: Johannes
authors.initials: J
authors.lastname: Hierholzer
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000379:methods*; D001843:Bone Cements; D002102:Cadaver; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000000981:diagnostic imaging*; D006801:Humans; D066298:In Vitro Techniques; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*; D054854:Vertebroplasty
chemical_list: D001843:Bone Cements