title: Gastric infiltration of diffuse large B-cell lymphoma: endoscopic diagnosis and improvement of lesions after chemotherapy.
abstract: Diffuse large B-cell lymphoma (DLBCL) is the most common histologic subtype of the non-Hodgkin's lymphoma (NHL) accounting for about 40% of all NHLs. This is a case report about the endoscopic appearance of a DLBCL with infiltration to the stomach in a 39-year-old female. She had a 6-mo history of lumbar and left upper quadrant pain with intermittent episodes of melena. A computer tomograghy (CT) scan showed mural thickening of the gastric antrum. Endoscopic examination revealed multiple gastric ulcers. Definite diagnosis could be made by endoscopic biopsies and the patient had a good response to chemotherapy. This response correlated well with a further endoscopic follow-up. A follow-up endoscopic examination could be considered to evaluate a good response to chemotherapy in DLBCL patients with secondary gastric dissemination.
authors.affiliation: Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran", Vasco de Quiroga 15, Tlalpan 14000, Mexico City, Mexico. sergiozepeda@medscape.com
authors.forename: Sergio
authors.initials: S
authors.lastname: Zepeda-Gomez
authors.forename: Jesus
authors.initials: J
authors.lastname: Camacho
authors.forename: Edgar
authors.initials: E
authors.lastname: Oviedo-Cardenas
authors.forename: Carmen
authors.initials: C
authors.lastname: Lome-Maldonado
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001706:Biopsy; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D008495:Medical Oncology / Q000379:methods; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D013270:Stomach / Q000473:pathology*; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary
chemical_list: D000970:Antineoplastic Agents