"Nonsolvent" applications of ionic liquids in biotransformations and organocatalysis.
The application of room-temperature ionic liquids (RTILs) as (co)solvents and/or reagents is well documented. However, RTILS also have "nonsolvent" applications in biotransformations and organocatalysis. Examples are the anchoring of substrates to RTILs; ionic-liquid-coated enzymes (ILCE) and enzyme-IL colyophilization; the construction of biocatalytic ternary reaction systems; the combination of enzymes, RTILs, membranes, and (bio)electrochemistry; and ionic-liquid-supported organocatalysts. These strategies provide more robust, more efficient, and more enantioselective bio- and organocatalysts with many practical applications. As shown herein, RTILs offer a wide range of promising alternatives to conventional chemistry.
Domínguez de María
Pablo
P
AkzoNobel BV, Chemicals Process and Product Technology Department, Velperweg 76, P.O. Box 9300, 6800 SB Arnhem, The Netherlands. pablo.dominguez@akzonobel.com
D001711:Biotransformation; D002384:Catalysis; D004795:Enzyme Stability; D004798:Enzymes / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D004798:Enzymes; D052578:Ionic Liquids; D009930:Organic Chemicals; D012997:Solvents