[Finasteride preoperative preparation of patients with prostatic adenoma to transurethral prostatic resection].
Finasteride effect before transurethral resection (TUR) of the prostatic gland was studied in 88 patients with prostatic adenoma (PA). Forty seven patients received prosteride (Gedeon Richter), forty one patients - proscar (MSD) in a dose 5 mg/day for 3 months. Finasteride reduced blood flow in prostatic tissue, density of the vascular plexus, epithelium/stroma coefficient from 1.26 to 0.84. This decreased intraoperative blood loss, postoperative hematuria, TUR duration, postoperative rehabilitation, number of early and late TUR complications.
Tkachuk
V N
VN
Al'-Shukri
S Kh
SKh
Tkachuk
I N
IN
D000368:Aged; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D004791:Enzyme Inhibitors / Q000008:administration & dosage*; D018120:Finasteride / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods; D011467:Prostate / Q000098:blood supply / Q000601:surgery*; D011470:Prostatic Hyperplasia / Q000601:surgery*; D012039:Regional Blood Flow / Q000187:drug effects
D004791:Enzyme Inhibitors; D018120:Finasteride