title: Candidemia in the 21st century.
abstract: The 21st century has brought forth vast innovations in the healthcare field. The availability and use of aggressive chemotherapeutic and immunosuppressive agents as well as broad-spectrum antibacterial agents has created a large population of patients who are at increased risk of acquiring infections with fungal organisms, especially Candida species. This review will focus on the changing epidemiology of candidal bloodstream infections, its impact on healthcare and new advances in the diagnosis and treatment of candidemia.
authors.affiliation: Division of Infectious Diseases, Thomas Jefferson University, Suite 210, 211 South 9th Street, Philadelphia, PA 19107, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Chang
authors.forename: Dionissios
authors.initials: D
authors.lastname: Neofytos
authors.forename: David
authors.initials: D
authors.lastname: Horn
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D003695:Delivery of Health Care / Q000706:statistics & numerical data / Q000639:trends; D006801:Humans; D017410:Practice Guidelines as Topic; D014481:United States / Q000453:epidemiology
chemical_list: D000935:Antifungal Agents