Biological and pathobiological functions of gelatinase dimers and complexes.
The two matrix metalloproteinases, MMP-2 and MMP-9, are known to form various dimer complexes. In the present review, some of these complexes are described along with their biological and pathobiological functions.
Malla
Nabin
N
Department of Medical Biochemistry, Institute of Medical Biology, Medical Faculty, University of Tromsø, Tromsø, Norway.
Sjøli
Stian
S
Winberg
Jan-Olof
JO
Hadler-Olsen
Elin
E
Uhlin-Hansen
Lars
L
D000818:Animals; D019281:Dimerization; D005109:Extracellular Matrix / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism*; D006242:Haptoglobins / Q000378:metabolism; D006801:Humans; D054834:Lipocalins / Q000378:metabolism; D020778:Matrix Metalloproteinase 2 / Q000737:chemistry / Q000378:metabolism*; D020780:Matrix Metalloproteinase 9 / Q000737:chemistry / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism*; D019714:Tissue Inhibitor of Metalloproteinases / Q000378:metabolism*; D000509:alpha-Fetoproteins / Q000378:metabolism
D006025:Glycosaminoglycans; D006242:Haptoglobins; D054834:Lipocalins; D011509:Proteoglycans; D019714:Tissue Inhibitor of Metalloproteinases; D000509:alpha-Fetoproteins; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9