title: Predicted and observed in-hospital mortality after left main coronary artery stenting in 204 patients.
abstract: BACKGROUND
  The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM).
  
  
  METHODS
  We studied 204 patients treated with elective or emergent coronary angioplasty. We estimated in-hospital mortality using the EuroSCORE, Parsonnet and GRACE risk scores and compared this data with actual in-hospital mortality.
  
  
  RESULTS
  There were no deaths among 62 patients undergoing elective PCI LM regardless of the estimated risk. Acute coronary syndrome (ACS) was diagnosed in all 142 patients undergoing emergent PCI LM. Mortality in this group was 24% (34/142). Area under receiver operating characteristic curve (AUC) values for the EuroSCORE, Parsonnet and GRACE risk scores in patients with ACS were 0.812 (p = 0.0001), 0.857 (p = 0.0001), and 0.870 (p = 0.0001), respectively. No statistically significant differences were found when these AUC values for different evaluated risk scores were compared. Overall, the EuroSCORE and Parsonnet risk scores had no discriminative value, as all deaths occurred in the highest risk group. Only the GRACE risk score discriminated risk among intermediate- and high-risk patients with ACS.
  
  
  CONCLUSIONS
  The EuroSCORE and Parsonnet scoring systems are of no value in predicting periprocedural mortality risk in patients undergoing elective PCI LM. Overall, discriminative ability of the EuroSCORE, Parsonnet, and GRACE risk scores in unselected patients with ACS undergoing emergent PCI LM was good. In this group of patients, the EuroSCORE and Parsonnet scoring systems had no discriminative value in low and moderate risk patients. Only the GRACE risk score discriminated risk among intermediate and high risk patients.
authors.affiliation: Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Toruń, Poland. adamsuk@cm.umk.pl
authors.forename: Adam
authors.initials: A
authors.lastname: Sukiennik
authors.forename: Joanna
authors.initials: J
authors.lastname: Ostrowska-Nowak
authors.forename: Joanna
authors.initials: J
authors.lastname: Wiśniewska-Szmyt
authors.forename: Marek
authors.initials: M
authors.lastname: Radomski
authors.forename: Marcin
authors.initials: M
authors.lastname: Rychter
authors.forename: Mirosław
authors.initials: M
authors.lastname: Jabłoński
authors.forename: Tomasz
authors.initials: T
authors.lastname: Białoszyński
authors.forename: Marek
authors.initials: M
authors.lastname: Koziński
authors.forename: Tomasz
authors.initials: T
authors.lastname: Fabiszak
authors.forename: Ryszard
authors.initials: R
authors.lastname: Dobosiewicz
authors.forename: Ewa
authors.initials: E
authors.lastname: Zabielska
authors.forename: Tamara
authors.initials: T
authors.lastname: Sukiennik
authors.forename: Aldona
authors.initials: A
authors.lastname: Kubica
authors.forename: Anna
authors.initials: A
authors.lastname: Król
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Demidowicz
authors.forename: Maciej
authors.initials: M
authors.lastname: Chojnicki
authors.forename: Zofia
authors.initials: Z
authors.lastname: Grabczewska
authors.forename: Iwona
authors.initials: I
authors.lastname: Swiatkiewicz
authors.forename: Maria
authors.initials: M
authors.lastname: Bogdan
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Grześk
authors.forename: Jacek
authors.initials: J
authors.lastname: Kubica
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D003324:Coronary Artery Disease / Q000401:mortality* / Q000628:therapy*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome