Ruthenium catalyzed biomimetic oxidation in organic synthesis inspired by cytochrome P-450.
Simulation of the function of cytochrome P-450 with low valent ruthenium complex catalysts leads to the discovery of biomimetic, catalytic oxidation of various substrates selectively under mild conditions. The reactions discussed in this tutorial review are simple, clean, and practical. The principle of these reactions is fundamental and gives wide-scope and environmentally benign future practical methods.
Murahashi
Shun-Ichi
S
Department of Chemistry, Okayama University of Science, Okayama, Japan. murahashi@high.ous.ac.jp
Zhang
Dazhi
D
D040761:Biomimetic Materials / Q000737:chemistry*; D002384:Catalysis; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry / Q000378:metabolism*; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D012428:Ruthenium / Q000737:chemistry*
D009930:Organic Chemicals; D012428:Ruthenium; D003577:Cytochrome P-450 Enzyme System