Microtubule stabilization: formins assert their independence.
Mammalian Diaphanous-related (mDia) formins are well known for their actin nucleation and filament elongation activities. They have since emerged as microtubule-binding proteins, and a recent study shows that mDia2 stabilizes microtubules independently of its actin nucleation activity.
DeWard
Aaron D
AD
Laboratory of Cell Structure and Signal Integration, Van Andel Research Institute, 333 Bostwick Ave., N.E., Grand Rapids, Michigan 49503, USA.
Alberts
Arthur S
AS
D000199:Actins / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000737:chemistry / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological; D011485:Protein Binding
D000199:Actins; D002352:Carrier Proteins; D008869:Microtubule-Associated Proteins