[Changes of seminal parameters, zinc concentration and antibacterial activity in patients with non-inflammatory chronic prostatitis/chronic pelvic pain syndrome].
OBJECTIVE
To investigate the seminal parameters, zinc concentration and antibacterial activity in patients with non- inflammatory chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).


METHODS
Seminal parameters, zinc concentration and antibacterial activity of seminal plasma were detected in 60 CP/CPPS patients and 20 normal men.


RESULTS
Statistically significant differences were found in the duration of semen liquefaction, sperm vitality, sperm motility, zinc concentration and antibacterial activity of the seminal plasma between the CP/CPPS and the control males ( P < 0.01). Zinc concentration was significantly correlated with the duration of sperm motility (r = 0. 272, P = 0.015) and antibacterial activity of the seminal plasma (r = 0.449, P < 0.01) in the CP/CPPS patients.


CONCLUSIONS
CP/CPPS has a significant negative impact on semen liquefaction, sperm motility and vitality, zinc concentration and antibacterial activity of seminal plasma. The antibacterial activity of seminal plasma is positively correlated with zinc concentration and sperm motility.
Zhao
Hui
H
Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Shen
Ji-hong
JH
Chen
Yu-ping
YP
Yu
Zhi-yong
ZY
Dong
Qiang
Q
Li
Hong
H
D002908:Chronic Disease; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D017699:Pelvic Pain / Q000473:pathology / Q000503:physiopathology*; D011472:Prostatitis / Q000503:physiopathology*; D012661:Semen / Q000737:chemistry* / Q000166:cytology; D013076:Sperm Count; D013081:Sperm Motility; D013577:Syndrome; D015032:Zinc / Q000032:analysis*
D015032:Zinc