title: Clinical application of magnification endoscopy and narrow-band imaging in the upper gastrointestinal tract: new imaging techniques for detecting and characterizing gastrointestinal neoplasia.
abstract: This article introduces one of the most advanced endoscopy imaging techniques, magnification endoscopy with narrow-band imaging. This technique can clearly visualize the microvascular (MV) architecture and microsurface (MS) structure. The application of this technique is quite useful for characterizing the mucosal neoplasia in the hypopharynx, oropharynx, esophagus, and stomach. The key characteristic findings for early carcinomatous lesions are an irregular MV pattern or irregular MS pattern as visualized by this technique. Such a diagnostic system could be applied to the early detection of mucosal neoplasia throughout the upper gastrointestinal tract.
authors.affiliation: Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin, Chikushino-city, Fukuoka, Japan. yao@fukuoka-u.ac.jp
authors.forename: Kenshi
authors.initials: K
authors.lastname: Yao
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takaki
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Matsui
authors.forename: Akinori
authors.initials: A
authors.lastname: Iwashita
authors.forename: George K
authors.initials: GK
authors.lastname: Anagnostopoulos
authors.forename: Philip
authors.initials: P
authors.lastname: Kaye
authors.forename: Krish
authors.initials: K
authors.lastname: Ragunath
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004947:Esophagus / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000473:pathology; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D041981:Gastrointestinal Tract / Q000473:pathology*; D006801:Humans; D008853:Microscopy