title: Solid variant of primary effusion lymphoma in successfully treated HIV infection: a case report.
abstract: Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, mainly met in severely immunocompromised, HIV-positive patients. PEL is aetiologically related to human herpes virus-8 (HHV-8) and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumour mass. Recently, cases of HIV-positive patients with HHV-8-positive solid tissue lymphomas, not associated with an effusion, have been reported (solid variant of PEL). The prognosis of PEL is reported to be poor. We report a case of an HIV-positive patient with a typical solid variant of PEL without effusion. Interestingly, his disease developed while being on stable antiretroviral therapy (ART) with high CD4 counts. He had a relatively long survival with chemotherapy and ART.
authors.affiliation: Fifth Department of Internal Medicine, Evaggelismos Hospital, Athens, Greece. emylon@med.uoa.gr
authors.forename: E
authors.initials: E
authors.lastname: Mylona
authors.forename: I G
authors.initials: IG
authors.lastname: Baraboutis
authors.forename: O
authors.initials: O
authors.lastname: Georgiou
authors.forename: D
authors.initials: D
authors.lastname: Rondogianni
authors.forename: L J
authors.initials: LJ
authors.lastname: Lekakis
authors.forename: V
authors.initials: V
authors.lastname: Papastamopoulos
authors.forename: I
authors.initials: I
authors.lastname: Apostolidis
authors.forename: A T
authors.initials: AT
authors.lastname: Skoutelis
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D015497:HIV-1 / Q000187:drug effects; D019288:Herpesvirus 8, Human; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000473:pathology* / Q000821:virology; D054685:Lymphoma, Primary Effusion / Q000473:pathology* / Q000821:virology; D008297:Male; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents