title: Fishing lines, time-delayed guideposts, and other tricks used by developing pharyngeal neurons in Caenorhabditis elegans.
abstract: The 20 neurons that innervate the Caenorhabditis elegans pharynx form a simple nervous system that develops and operates in near complete isolation from the rest of the worm body and, therefore, offers a manageable degree of complexity for developmental genetics studies. This review discusses the progress that has been made in determining the mechanisms by which 4 of the 20 pharyngeal neurons develop, and emphasizes surprising processes that add to the classic growth cone guidance model which is usually thought to explain how most axons establish their trajectories.
authors.affiliation: Department of Cell Molecular Biology, University of Göteborg, Göteborg, Sweden. marc.pilon@cmb.gu.se
authors.forename: Marc
authors.initials: M
authors.lastname: Pilon
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology* / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D010614:Pharynx / Q000196:embryology* / Q000294:innervation / Q000502:physiology
chemical_list: D029742:Caenorhabditis elegans Proteins