Potential effect of excluding variant Creutzfeldt-Jakob disease on the eye donor pool in Australia.
OBJECTIVE
To quantitate the likely effect on the available eye donor pool by excluding potential donors who may have had exposure to variant Creutzfeldt-Jakob disease by virtue of spending time in countries where bovine spongiform encephalopathy (BSE) is endemic.


METHODS
A telephone survey by systematic sampling from the Brisbane phone directory was undertaken to ascertain the number of potential donors who had resided in the United Kingdom and in other countries.


RESULTS
Between 19% of potential donors would have had to have been excluded by virtue of residing in the United Kingdom for >6 months between 1980 and 1996 and 29% for those who had traveled to any other country in which BSE was identified.


CONCLUSIONS
This study suggests that adopting an eye bank policy of excluding donors potentially exposed to BSE would have a significant effect on donor numbers. Health departments and eye banks will need to weigh the small additional protection from such policy decisions against the likely effect on corneal tissue supply.
Hirst
Lawrence W
LW
Queensland Eye Bank, Princess Alexandra Hospital, Brisbane, Australia. lawrie.hirst@qei.org.au
Pascual
Cheryl
C
Madden
Peter
P
Whitby
Michael
M
McLaws
Mary-Louise
ML
D000818:Animals; D001315:Australia / Q000453:epidemiology; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology*; D016643:Encephalopathy, Bovine Spongiform / Q000453:epidemiology / Q000635:transmission*; D005125:Eye Banks; D006306:Health Surveys; D006801:Humans; D007407:Interviews as Topic; D011159:Population Surveillance; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014019:Tissue Donors / Q000706:statistics & numerical data*; D014195:Travel / Q000706:statistics & numerical data*; D006113:United Kingdom / Q000453:epidemiology