[Influence of prenatal stress on free radical oxidation lipids, both proteins and activity of superoxiddismutase in neurones and glial cells of the rat brain cortex].
Processes of free radical oxidation of protein, lipids, and activity of superoxiddismutase in neurons and glial cells of the rat brain cortex in ontogenesis and after prenatal stress. Irrespective of age, the level of free radical oxidation of lipids and proteins in neurons is higher in comparison with the glia. The same was found in the study of superoxiddismutase activity. After prenatal stress, the level of free radical oxidation of lipids is reduced both in neurons, and in the glia. On the contrary, the contents of oxidation of proteins rises in neurons on the average fourfold. Activity of superoxiddismutase in animals who had suffered from prenatal stress is considerably reduced in neurons remaining unchanged in glial cells.
Flerov
M A
MA
Gerasimova
I A
IA
V'iushina
A V
AV
Pritvorova
A V
AV
D000818:Animals; D000831:Animals, Newborn; D002540:Cerebral Cortex / Q000378:metabolism* / Q000473:pathology; D005260:Female; D005609:Free Radicals / Q000378:metabolism*; D007103:Immobilization / Q000009:adverse effects*; D050356:Lipid Metabolism; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009457:Neuroglia / Q000378:metabolism* / Q000473:pathology; D009474:Neurons / Q000378:metabolism* / Q000473:pathology; D010084:Oxidation-Reduction; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D013482:Superoxide Dismutase / Q000378:metabolism
D005609:Free Radicals; D009419:Nerve Tissue Proteins; D013482:Superoxide Dismutase