title: Pediatric experience with the VentrAssist LVAD.
abstract: OBJECTIVE
  The purpose of this study is to describe the first experience of implanting a new left ventricular assist device in pediatric patients with end-stage heart failure.
  
  
  METHODS
  In two recent prospective, international, multicenter clinical trials, three children (aged </= 16 years) were implanted successfully with the VentrAssist (Ventracor Limited, Chatswood, Australia), a relatively small, novel, continuous flow, third-generation left ventricular assist device.
  
  
  RESULTS
  Despite the patients' disease severity (each child was in extremis at the time of implantation), VentrAssist (Ventracor Limited) implantation enabled each patient to be discharged home from the hospital. All patients survived for more than 1 year. One patient was successfully transplanted and another was bridged to an adequate degree of recovery; unfortunately, the third patient died on postoperative day 375 while waiting for a suitable donor heart. Consistent with the complications associated with left ventricular assist devices in adults, the main complications in these pediatric patients were infection and thromboembolism.
  
  
  CONCLUSIONS
  The VentrAssist may provide a major advancement in the management of larger children and adolescents with end-stage heart failure.
authors.affiliation: New Zealand Heart and Lung Transplant Service, Auckland City Hospital, Auckland, New Zealand. pruygrok@adhb.govt.nz
authors.forename: Peter N
authors.initials: PN
authors.lastname: Ruygrok
authors.forename: Don S
authors.initials: DS
authors.lastname: Esmore
authors.forename: Peter M
authors.initials: PM
authors.lastname: Alison
authors.forename: Kirsten A
authors.initials: KA
authors.lastname: Finucane
authors.forename: Shay P
authors.initials: SP
authors.lastname: McGuinness
authors.forename: Alastair D
authors.initials: AD
authors.lastname: McGeorge
authors.forename: Justin
authors.initials: J
authors.lastname: Negri
authors.forename: Kylie
authors.initials: K
authors.lastname: Jones
authors.forename: Helen C
authors.initials: HC
authors.lastname: Gibbs
mesh_terms: D000293:Adolescent; D002311:Cardiomyopathy, Dilated / Q000601:surgery; D002648:Child; D003131:Combined Modality Therapy; D004867:Equipment Design; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology