title: Carotid angioplasty and stenting vs carotid endarterectomy for treatment of asymptomatic disease: single-center experience.
abstract: BACKGROUND
  Carotid angioplasty and stenting (CAS) with embolic protection is an acceptable alternative to carotid endarterectomy (CEA) in selected patients with symptomatic cervical carotid artery disease. Whether outcomes after CAS are comparable to those after CEA in the larger population of patients with asymptomatic disease is unclear.
  
  
  OBJECTIVE
  Carotid angioplasty and stenting performed in patients with asymptomatic disease will result in early outcomes equivalent to those with CEA performed in patients with asymptomatic disease at our center and in 2 landmark studies of CEA.
  
  
  METHODS
  Single-center retrospective review.
  
  
  METHODS
  Urban hospital.
  
  
  METHODS
  Three hundred twenty-six patients (202 men [62%] and 124 women [38%]; mean age, 71 years) with asymptomatic carotid artery stenoses treated with either CAS (n = 120) or CEA (n = 206) between January 1, 2001, and December 31, 2006. Overall mean degree of stenosis was 81.2%.
  
  
  METHODS
  Carotid angioplasty and stenting was performed using self-expanding nitinol stents coupled with a mechanical embolic protection system. Carotid endarterectomy was performed using general anesthesia with selective shunting based on carotid stump pressure.
  
  
  METHODS
  Stroke, myocardial infarction, and death rates at 30 days after surgery.
  
  
  RESULTS
  At 30 days after surgery, there was no statistical difference between outcomes after CAS (2 strokes [1.7%], 2 myocardial infarctions [1.7%], and 1 death [0.8%]) compared with CEA (2 strokes [1.0%], 3 myocardial infarctions [1.5%], and no deaths).
  
  
  CONCLUSIONS
  Vascular surgeons who have advanced catheter-based skills can safely perform CAS in patients with asymptomatic disease with periprocedural results comparable to those with CEA.
authors.affiliation: Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, 201 E Huron St, Galter 10-105, Chicago, IL 60611, USA. meskanda@nmh.org
authors.forename: Gale L
authors.initials: GL
authors.lastname: Tang
authors.forename: Jon S
authors.initials: JS
authors.lastname: Matsumura
authors.forename: Mark D
authors.initials: MD
authors.lastname: Morasch
authors.forename: William H
authors.initials: WH
authors.lastname: Pearce
authors.forename: Antoinette
authors.initials: A
authors.lastname: Nguyen
authors.forename: Daniel
authors.initials: D
authors.lastname: Amaranto
authors.forename: Mark K
authors.initials: MK
authors.lastname: Eskandari
mesh_terms: D000800:Angioplasty, Balloon; D016893:Carotid Stenosis / Q000601:surgery*; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D015607:Stents