Cationic cyclocholamides; toroidal facial amphiphiles with potential for anion transport.
Cholic acid has been transformed into cyclotrimeric and cyclotetrameric toroidal amphiphiles with inward-directed ammonium substituents; the cyclotrimer effects the transport of chloride anions across vesicle bilayer membranes.
Whitmarsh
Samuel D
SD
School of Chemistry, University of Bristol, Cantock's Close, Bristol, UKBS8 1TS.
Redmond
Adrian P
AP
Sgarlata
Valentina
V
Davis
Anthony P
AP
D000838:Anions / Q000737:chemistry*; D019826:Cholic Acid / Q000737:chemistry*; D017136:Ion Transport; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D011083:Polycyclic Compounds / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry
D000838:Anions; D047028:Macrocyclic Compounds; D011083:Polycyclic Compounds; D013501:Surface-Active Agents; D019826:Cholic Acid