Phylogenetic analysis of viridans group streptococci causing endocarditis.
Identification of viridans group streptococci (VGS) to the species level is difficult because VGS exchange genetic material. We performed multilocus DNA target sequencing to assess phylogenetic concordance of VGS for a well-defined clinical syndrome. The hierarchy of sequence data was often discordant, underscoring the importance of establishing biological relevance for finer phylogenetic distinctions.
Simmon
Keith E
KE
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA.
Hall
Lori
L
Woods
Christopher W
CW
Marco
Francesc
F
Miro
Jose M
JM
Cabell
Christopher
C
Hoen
Bruno
B
Marin
Mercedes
M
Utili
Riccardo
R
Giannitsioti
Efthymia
E
Doco-Lecompte
Thanh
T
Bradley
Suzanne
S
Mirrett
Stanley
S
Tambic
Arjana
A
Ryan
Suzanne
S
Gordon
David
D
Jones
Phillip
P
Korman
Tony
T
Wray
Dannah
D
Reller
L Barth
LB
Tripodi
Marie-Francoise
MF
Plesiat
Patrick
P
Morris
Arthur J
AJ
Lang
Selwyn
S
Murdoch
David R
DR
Petti
Cathy A
CA
D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006801:Humans; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000382:microbiology*; D034363:Viridans Streptococci / Q000235:genetics*