Seventeen-year-old mother-to-child HIV type 1 transmission identified by phylogeny and signature patterns.
A case, in which the clinical suspicion of perinatal HIV transmission of a newly diagnosed 17-year-old woman was supported by the phylogenetic analyses of pol sequences obtained for routine resistance testing and further substantiated by analyses of gag and env, is described.
Katzenstein
Terese L
TL
Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark. terese.katzenstein@rh.regionh.dk
Petersen
Ann Berith
AB
Jørgensen
Louise Bruun
LB
Strand
Tine Johanne
TJ
Madsen
Tina Vasehus
TV
Gerstoft
Jan
J
D000293:Adolescent; D001483:Base Sequence; D005260:Female; D005814:Genes, Viral / Q000235:genetics*; D015658:HIV Infections / Q000635:transmission* / Q000821:virology; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008969:Molecular Sequence Data; D010802:Phylogeny; D011247:Pregnancy