In vitro withanolide production by Withania somnifera L. cultures.
In vitro multiple shoots, root, callus and cell suspension cultures of Withania somnifera exhibited the potentiality to produce pharmacologically active withanolides. Multiple shoots cultures exhibited an increase in withanolide A accumulation compared to shoots of the mother plant. In vitro generated root cultures as well as callus and suspension cultures also produced withanolides albeit at lower levels.
Sabir
Farzana
F
Central Institute of Medicinal and Aromatic Plants (CIMAP), P. O.-CIMAP, Lucknow-226015, India.
Sangwan
Neelam S
NS
Chaurasiya
Narayan D
ND
Misra
Laxmi N
LN
Sangwan
Rajender S
RS
D002478:Cells, Cultured; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000096:biosynthesis; D035264:Flowers / Q000378:metabolism; D007210:Indoleacetic Acids / Q000378:metabolism; D018515:Plant Leaves / Q000166:cytology / Q000378:metabolism; D018517:Plant Roots / Q000378:metabolism; D018520:Plant Shoots / Q000378:metabolism; D032341:Withania / Q000378:metabolism*; D054358:Withanolides
C433551:3-rhamnopyranosyl(1-4)-glucopyranosyl-12-diacetoxy-20-hydroxywitha-5,24-dienolide; D007210:Indoleacetic Acids; D054358:Withanolides; C030737:indoleacetic acid; D004875:Ergosterol