title: [Influence of non-depolarizing relaxant on facial nerve monitoring during total intravenous anesthesia].
abstract: OBJECTIVE
  To study the feasibility of using non-depolarizing relaxant in intraoperative facial nerve monitoring (IFNM) during total intravenous anesthesia (TIVA).
  
  
  METHODS
  Thirty adult patients, aged 37 (20-50), with ASA class I or II, without disorder of facial nerve, underwent IFNM during TIVA, using fentanyl, midazolam, and propofol, to record the compound muscle action potentials (CMAPs) of the facial nerve. Train of four (TOF) pattern was used to evaluate the degree of peripheral neuromuscular blockade. The relationship between the TOF value and CMAP was studied.
  
  
  RESULTS
  When the TOP value was 1 the wave amplitude of the CMAP of facial nerve was 0.19 +/- 0.08 mv, significantly lower than that when no muscle relaxant was used (2.72 +/- 0.34 mv, P < 0.01), however, when the TOF values were > or = 2 there were no statistically significant differences in the amplitude of the CMAP of facial nerve. In addition, clear graph of CMAP could be obtained when the TOF values were > or = 2.
  
  
  CONCLUSIONS
  IFNM can be safely and efficaciously performed when neuromuscular blockade is monitored carefully during TIVA.
authors.affiliation: Department of Anesthesia, Unit of Neuroelectrophysiology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Yan-hao
authors.initials: YH
authors.lastname: Gu
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Liang
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000328:Adult; D000768:Anesthesia, General / Q000379:methods; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000494:pharmacology*; D004576:Electromyography; D005154:Facial Nerve / Q000187:drug effects* / Q000502:physiology; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D008297:Male; D008874:Midazolam / Q000008:administration & dosage / Q000494:pharmacology; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage / Q000494:pharmacology*; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol