title: Moyamoya vasculopathy in a child after hemolytic uremic syndrome: a possible etiopathogenesis.
abstract: Moyamoya disease is a cerebral vasculopathy of unknown etiology frequently seen in the Asian population. We report a case of moyamoya vasculopathy in an African-American child who had renal failure followed by cerebral ischemia. Our patient presented with hemolytic uremic syndrome (HUS) and renal failure, and later developed seizures. We believe that in this patient HUS led to the pathogenesis of moyamoya disease. We suggest that patients with HUS who develop any neurological symptoms should be investigated for moyamoya vasculopathy for early diagnosis and treatment.
authors.affiliation: Department of Pediatrics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612, USA. msingla@uic.edu
authors.forename: M
authors.initials: M
authors.lastname: Singla
authors.forename: E
authors.initials: E
authors.lastname: John
authors.forename: G
authors.initials: G
authors.lastname: Hidalgo
authors.forename: D
authors.initials: D
authors.lastname: Grewal
authors.forename: C
authors.initials: C
authors.lastname: Macmillan
mesh_terms: D001741:Black or African American; D002545:Brain Ischemia / Q000209:etiology / Q000473:pathology; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000473:pathology; D006801:Humans; D009072:Moyamoya Disease / Q000175:diagnosis / Q000209:etiology*; D051437:Renal Insufficiency / Q000150:complications / Q000473:pathology; D012640:Seizures / Q000209:etiology / Q000473:pathology