title: Exacerbation of Mycoplasma gallisepticum infection in turkeys by rhinotracheitis virus.
abstract: Groups of 1-day-old turkey poults from a parent flock free of antibodies to turkey rhinotracheitis virus (TRTV) and the pathogenic mycoplasmas, were infected by eyedrop with virulent TRTV, with Mycoplasma gallisepticum (Mg) or with both agents together. Dual infection resulted in increased morbidity compared with those groups given single infections. The presence of the Mg in the dual infection had no apparent effect on the pathogenesis of the virus, but the virus caused the Mycoplasma to be more invasive. Mg infection caused a transient depression in TRTV ELISA antibody titres at 29 days post-inoculation. At 14 days post-infection Mg haemagglutination inhibition (HI) and rapid serum agglutination (RSA) titres were higher (P <0.01) in the mixed infection group compared with those infected with Mg alone, but there was no significant difference between ELISA antibody titres of these two groups.
authors.affiliation: Department of Veterinary Pathology, University of Liverpool, Neston, Wirral, England.
authors.forename: C J
authors.initials: CJ
authors.lastname: Naylor
authors.forename: A R
authors.initials: AR
authors.lastname: Al-Ankari
authors.forename: A I
authors.initials: AI
authors.lastname: Al-Afaleq
authors.forename: J M
authors.initials: JM
authors.lastname: Bradbury
authors.forename: R C
authors.initials: RC
authors.lastname: Jones