title: The value of a combination of wire localization and ultrasound-guided vacuum-assisted breast biopsy for clustered microcalcifications.
abstract: The purpose of this study is to introduce and evaluate the usefulness of the combination of wire localization and ultrasound (US)-guided, vacuum-assisted breast biopsy (VAB) to histologically diagnose mammographically detected clustered microcalcifications in the absence of sonographic and clinically palpable masses. Fifty-eight consecutive patients (mean age 53 years) with 58 mammographically detected microcalcification clusters underwent mammographically guided wire localization followed by VAB with US guidance for targeting the wire. Mammography of the specimens obtained was performed in all cases for identification of microcalcifications. The procedure took approximately 24 min (range, 18-52 min). No significant immediate and delayed complications were observed. Microcalcifications were evident on both specimen radiographs and microscopic slides in 56 cases (97%). The combination of wire localization and US-guided VAB could provide an accurate and useful method for diagnosing mammographically detected, clustered microcalcifications.
authors.affiliation: Department of Radiology, Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, 10, 1-Ga, Ami-Dong, Seo-Ku, Busan 602-739, Republic of Korea.
authors.forename: Ki Seok
authors.initials: KS
authors.lastname: Choo
authors.forename: Hee Suk
authors.initials: HS
authors.lastname: Kwak
authors.forename: Young
authors.initials: Y
authors.lastname: Tae Bae
authors.forename: Jee-Yeon
authors.initials: JY
authors.lastname: Lee
authors.forename: Seung Ju
authors.initials: SJ
authors.lastname: Lee
authors.forename: Hyoung Il
authors.initials: HI
authors.lastname: Seo
authors.forename: Su Bong
authors.initials: SB
authors.lastname: Nam
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods*; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D016217:Ultrasonography, Mammary; D014618:Vacuum