title: Recurrent gastric perforation as a late complication of radiotherapy for mucosa-associated lymphoid tissue lymphoma of the stomach.
abstract: Radiation therapy can be used to treat Helicobacter pylori-negative or eradication-refractory extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) of the stomach. We report a case of gastric perforation which occurred more than 1 year after the completion of radiotherapy for H. pylori eradication-refractory gastric MALT lymphoma, and then recurred shortly afterwards. This was considered to be a late complication of radiation toxicity. Although gastric perforation due to radiotherapy has been reported very rarely in the past, even in advanced disease, this case shows that perforation can develop in patients with superficial disease and can relapse.
authors.affiliation: Department of Internal Medicine, Karatsu Red Cross Hospital. ootsuka-t@koseikan.jp
authors.forename: Taiga
authors.initials: T
authors.lastname: Otsuka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Noda
authors.forename: Masako
authors.initials: M
authors.lastname: Yokoo
authors.forename: Kazuo
authors.initials: K
authors.lastname: Ibaraki
mesh_terms: D000368:Aged; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000175:diagnosis*; D011878:Radiotherapy / Q000009:adverse effects*; D012008:Recurrence; D012421:Rupture; D013270:Stomach / Q000293:injuries* / Q000528:radiation effects; D013274:Stomach Neoplasms / Q000532:radiotherapy*