title: Implantation of a left ventricular assist device in a patient with primary antiphospholipid syndrome.
abstract: The antiphospholipid syndrome is characterized by arterial and venous thrombosis and is associated with the presence of circulating antiphospholipid antibodies. Arterial thrombosis can result in myocardial infarction, which may potentially lead to end-stage heart failure. Here we report our anticoagulation protocol for patients with antiphospholipid syndrome that undergo axial-flow left ventricle assist devices (HeartMate II; Thoratec, Pleasanton, CA) implantation.
authors.affiliation: Department of Cardiothoracic, Transplant, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Anna Lassia
authors.initials: AL
authors.lastname: Meyer
authors.forename: Christian
authors.initials: C
authors.lastname: Kuehn
authors.forename: Clemens
authors.initials: C
authors.lastname: Gras
authors.forename: Doris
authors.initials: D
authors.lastname: Malehsa
authors.forename: Christoph
authors.initials: C
authors.lastname: Bara
authors.forename: Stefan
authors.initials: S
authors.lastname: Fischer
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.forename: Martin
authors.initials: M
authors.lastname: Strüber
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D058846:Antibodies, Monoclonal, Murine-Derived; D000925:Anticoagulants / Q000008:administration & dosage; D018951:Antigens, CD20; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000628:therapy; D006333:Heart Failure / Q000150:complications / Q000628:therapy*; D006353:Heart-Assist Devices; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D010951:Plasma Exchange; D010956:Plasmapheresis; D011300:Preoperative Care; D019919:Prosthesis Implantation / Q000379:methods*; D000069283:Rituximab; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000925:Anticoagulants; D018951:Antigens, CD20; D000069283:Rituximab; D014859:Warfarin; D006493:Heparin