title: An efficient method for the synthesis of vinylbromohydrin and vinylbromoalkoxy derivatives and cyclocarbonylation of alpha-allenic alcohols catalyzed by palladium chloride.
abstract: Vinylidenecyclopropanes undergo hydrobromination or alkoxybromination in the presence of N-bromosuccinimide and water or alcohols to give the corresponding vinylbromohydrin and vinylbromoalkoxy derivatives in moderate to excellent yields at room temperature. These vinylbromohydrin derivatives can be easily transformed to alpha-allenic alcohols in the presence of Et3N under mild conditions. In addition, the cyclocarbonylation of alpha-allenic alcohols with CO catalyzed by palladium chloride to give the corresponding lactones under different reaction conditions has been described.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Shi