title: Dynamic left ventricular outflow tract obstruction without basal septal hypertrophy, caused by catecholamine therapy and volume depletion.
abstract: Hypertrophic cardiomyopathy (HCM) with hypertrophy of the basal septum is the most common etiology of left ventricular outflow tract (LVOT) obstruction. In this article, we report the case of a patient with a structurally normal heart who developed hemodynamic deterioration due to severe LVOT obstruction following treatment with catecholamines. Hypovolemia accompanied with a hyperdynamic condition, resulting from catecholamine treatment, may cause dynamic LVOT obstruction due to the systolic anterior motion of the mitral valve leaflet. The solution for this is early recognition and correction of aggravating factors such as, withdrawal of catecholamine therapy and volume replacement.
authors.affiliation: Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Yang
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Park
authors.forename: Jeong Hoon
authors.initials: JH
authors.lastname: Yang
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Cho
authors.forename: Hyo Song
authors.initials: HS
authors.lastname: Kim
authors.forename: Kyoung A
authors.initials: KA
authors.lastname: Choi
authors.forename: Ho Joong
authors.initials: HJ
authors.lastname: Kim
mesh_terms: D002395:Catecholamines / Q000009:adverse effects*; D006346:Heart Septum; D006801:Humans; D006984:Hypertrophy; D020896:Hypovolemia / Q000139:chemically induced / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010953:Plasma Volume; D014694:Ventricular Outflow Obstruction / Q000139:chemically induced* / Q000209:etiology
chemical_list: D002395:Catecholamines