Dynamics and determinants of Staphylococcus aureus carriage in infancy: the Generation R Study.
Serial nasal swabs were collected at the ages of 1.5, 6, and 14 months from 443 infants in the Generation R Study. The objective was to study the dynamics and determinants of Staphylococcus aureus nasal carriage in the first year of life. The prevalence of S. aureus carriage decreased in the first year of life, from 52.1% at the age of 1.5 months to 12.9% at 14 months. Persistent carriage, defined as continuous carriage of the same S. aureus strain at the three sampling moments, was rarely detected in early infancy.
Lebon
Ankie
A
The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.
Labout
Joost A M
JA
Verbrugh
Henri A
HA
Jaddoe
Vincent W V
VW
Hofman
Albert
A
van Wamel
Willem
W
Moll
Henriette A
HA
van Belkum
Alex
A
D000367:Age Factors; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009666:Nose / Q000382:microbiology; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*