[Clinical observation on catgut implantation at Shu- and Mu-acupoints for treatment of premature ovarian failure].
OBJECTIVE
To observe clinical therapeutic effect of catgut implantation at Shu- and Mu-acupoints of liver, spleen and kidney on premature ovarian failure.


METHODS
One hundred and thirty-two cases of premature ovarian failure were randomly divided into a catgut implantation group and a medication group, 66 cases in each group. The catgut implantation group were treated by catgut implantation at She- and Mu-acupoints of liver, spleen and kidney, and the medication group were treated with oral administration of Estradiol Valerate 2 mg, qd, for 20 days, and 10 days later, Medroxyprogesterone Acetate 4 mg was added, b. i. d, for 10 days, averaging 6 months of medication. The therapeutic effects and changes of serum follicle-stimulating hormone (FSH) and estradiol (E2) were observed in the two groups.


RESULTS
After treatment, serum FSH and E2 significantly improved in the two groups (P<0.01), with the serum E2 in the catgut implantation group increased more significantly than that in the medication group (P<0.01). The cured rate and the total effective rate were 84.9% and 97.0% in the catgut implantation group and 31.8% and 84.8% in the medication group, the cured rate in the catgut implantation group being better than that in the medication group (P<0.05). Ten month later, the therapeutic effect in the catgut implantation group was kept.


CONCLUSIONS
Catgut implantation at Shu- and Me-acupoints of liver, spleen and kidney has a good therapeutic effect on premature ovarian failure with no side effect.
Liu
Hong-Jiao
HJ
First Clinical Medical College, Guangzhou University of TCM, Guangdong 510405, China. hongjiao1029@163.com
Peng
Jian-Hong
JH
Xu
Xue-Bing
XB
D015669:Acupuncture Points; D000328:Adult; D002398:Catgut; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D016649:Primary Ovarian Insufficiency / Q000628:therapy*
D004958:Estradiol; D005640:Follicle Stimulating Hormone