Diagnostic accuracy of 3.0-Tesla rectal magnetic resonance imaging in preoperative local staging of primary rectal cancer.
OBJECTIVE
To evaluate the diagnostic accuracy of 3.0-T rectal magnetic resonance imaging (MRI) in the preoperative local staging of primary rectal cancer.


METHODS
Forty-two patients with surgically and pathologically proven primary rectal cancer who underwent preoperative gadobenate dimeglumine-enhanced 3.0-T rectal MRI, were enrolled in this retrospective study. Two radiologists, who were blinded to the pathology results, independently reviewed the MR images and recorded their confidence level for determination of perirectal extension, and regional lymph node (LN) involvement using a 5-point scale. The diagnostic accuracy of each reviewer for local staging was calculated by receiver operating characteristic (ROC) curve analysis. Interobserver agreement was also calculated using linear weighted kappa statistics.


RESULTS
The diagnostic accuracy (area under the ROC curve, Az) for determining perirectal extension was for reviewer 1, 0.860 (95% confidence interval, 0.72-0.95) and for reviewer 2, 0.853 (0.71-0.94), respectively. The Az for determination of regional LN involvement was for reviewer 1, 0.902 (0.77-0.97) and for reviewer 2, 0.843 (0.70-0.94), respectively. Interobserver agreement included, respectively, good, and moderate agreement for perirectal extension, and regional LN involvement (kappa = 0.662, and 0.522, respectively).


CONCLUSIONS
3.0-T rectal MRI can provide accurate information of perirectal extension and regional LN involvement in the preoperative local staging of primary rectal cancer.
Kim
Seung Ho
SH
Department of Radiology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.
Lee
Jeong Min
JM
Lee
Min Woo
MW
Kim
Gi Hyeon
GH
Han
Joon Koo
JK
Choi
Byung Ihn
BI
D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D009942:Organometallic Compounds; D011300:Preoperative Care; D012372:ROC Curve; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies
D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine