Changes in gray matter induced by learning--revisited.
BACKGROUND
Recently, activation-dependant structural brain plasticity in humans has been demonstrated in adults after three months of training a visio-motor skill. Learning three-ball cascade juggling was associated with a transient and highly selective increase in brain gray matter in the occipito-temporal cortex comprising the motion sensitive area hMT/V5 bilaterally. However, the exact time-scale of usage-dependant structural changes occur is still unknown. A better understanding of the temporal parameters may help to elucidate to what extent this type of cortical plasticity contributes to fast adapting cortical processes that may be relevant to learning.


RESULTS
Using a 3 Tesla scanner and monitoring whole brain structure we repeated and extended our original study in 20 healthy adult volunteers, focussing on the temporal aspects of the structural changes and investigated whether these changes are performance or exercise dependant. The data confirmed our earlier observation using a mean effects analysis and in addition showed that learning to juggle can alter gray matter in the occipito-temporal cortex as early as after 7 days of training. Neither performance nor exercise alone could explain these changes.


CONCLUSIONS
We suggest that the qualitative change (i.e. learning of a new task) is more critical for the brain to change its structure than continued training of an already-learned task.
Driemeyer
Joenna
J
Department of Systems Neuroscience, University of Hamburg (UKE), Hamburg, Germany.
Boyke
Janina
J
Gaser
Christian
C
Büchel
Christian
C
May
Arne
A
D000328:Adult; D001921:Brain / Q000033:anatomy & histology* / Q000473:pathology / Q000502:physiology; D002540:Cerebral Cortex / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007858:Learning; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D015233:Models, Statistical; D009473:Neuronal Plasticity; D012044:Regression Analysis