Ozonization and cyclic voltammetry as efficient methods for the regeneration of gelatin-coated SPR chips.
The application of ozonization and cyclic voltammetry for the regeneration of gold chips containing a chemisorbed gelatin layer is reported. The efficiency of the regeneration process was analyzed using various surface analysis techniques indicating a complete removal of the biopolymer layer. The current findings open up perspectives for regeneration and multiple application of gold chips for SPR measurements.
Van Vlierberghe
Sandra
S
Polymer Chemistry and Biomaterials Research Group, Ghent University, Ghent, Belgium.
De Wael
Karolien
K
Buschop
Hans
H
Adriaens
Annemie
A
Schacht
Etienne
E
Dubruel
Peter
P
D004563:Electrochemistry / Q000379:methods*; D005780:Gelatin / Q000737:chemistry*; D010126:Ozone / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods; D013438:Sulfhydryl Compounds / Q000737:chemistry; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
D013438:Sulfhydryl Compounds; D010126:Ozone; D005780:Gelatin