title: A case of ovarian endodermal sinus tumor diagnosed during pregnancy.
abstract: Pregnancy complicated by endodermal sinus tumor of the ovary is extremely rare. The authors present a case report of a pregnant woman with persistent left adnexal mass and subsequently found to have a primary endodermal sinus tumor of the ovary that was diagnosed at 19 weeks of gestation. After left salpingo-oophorectomy had been performed, the patient chose to terminate the pregnancy before the initiation of combination chemotherapy with bleomycin, etoposide, and cisplatin. The response to chemotherapy was not satisfactory. The patient expired after seven cycles of treatment had been completed because of pulmonary fibrosis and the drug toxicity of bleomycin.
authors.affiliation: Department of Obstetrics and Gynecology, Falculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. iisarink@yahoo.com
authors.forename: Isarin
authors.initials: I
authors.lastname: Thanaboonyawat
authors.forename: Mongkol
authors.initials: M
authors.lastname: Benjapibal
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects / Q000627:therapeutic use; D001761:Bleomycin / Q000009:adverse effects / Q000627:therapeutic use; D002945:Cisplatin / Q000009:adverse effects / Q000627:therapeutic use; D018240:Endodermal Sinus Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005047:Etoposide / Q000009:adverse effects / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D010052:Ovariectomy / Q000379:methods; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011658:Pulmonary Fibrosis / Q000139:chemically induced
chemical_list: D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin