title: Coagulopathy in patients who experience snakebite.
abstract: OBJECTIVE
  Coagulopathy is a common complication of snakebite, but there is little information on the clinical importance of coagulopathy. We analyzed the characteristics of coagulopathy after envenomation.
  
  
  METHODS
  Ninety-eight patients who experienced snakebite were enrolled in this study. We divided all the patients into three groups by the ISTH DIC scoring system: the normal, simple coagulopathy and DIC groups. The coagulopathy group included both the simple coagulopathy and DIC groups. We then conducted a case-control study.
  
  
  RESULTS
  There was a significant decrease in the Hct, protein, albumin, ALP and cholesterol levels in the coagulopathy group, and only the cholesterol level was deceased in the DIC group (0<0.05). Leukocytosis and rhabdomyolysis were significantly associated with coagulopathy, and hemolysis and rhabdomyolysis were associated with DIC (p<0.05). The presence of rhabdomyolysis was considered a risk factor for coagulopathy (p<0.05). These conditions continued for up to six to seven days after the snakebite.
  
  
  CONCLUSIONS
  Evaluation of coagulopathy with using these characteristics is helpful to properly manage the patients who experience snakebite.
authors.affiliation: Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Jae Seok
authors.initials: JS
authors.lastname: Kim
authors.forename: Jae Won
authors.initials: JW
authors.lastname: Yang
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Kim
authors.forename: Seung Tae
authors.initials: ST
authors.lastname: Han
authors.forename: Bi Ro
authors.initials: BR
authors.lastname: Kim
authors.forename: Myung Sang
authors.initials: MS
authors.lastname: Shin
authors.forename: Jong In
authors.initials: JI
authors.lastname: Lee
authors.forename: Byoung Geun
authors.initials: BG
authors.lastname: Han
authors.forename: Seung Ok
authors.initials: SO
authors.lastname: Choi
mesh_terms: D000818:Animals; D001778:Blood Coagulation Disorders / Q000209:etiology*; D016022:Case-Control Studies; D005260:Female; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D015994:Incidence; D007964:Leukocytosis / Q000209:etiology; D008297:Male; D012189:Retrospective Studies; D012206:Rhabdomyolysis / Q000209:etiology; D012307:Risk Factors; D012909:Snake Bites / Q000150:complications*