Right atrial thrombus from inferior vena cava after acute cardiotoxicity of 5-fluorouracil.
We reported a case of large right atrial thrombus which migrated from the inferior vena cava after acute left ventricular dysfunction due to 5-Fluorouracil cardiotoxicity. The patient had recurrent episodes of chest pain and dyspnea suggestive of pulmonary thromboembolism and several days later control echocardiography showed that the right atrial thrombus had disappeared. The patient was discharged with oral anticoagulant therapy with no further clinical sequelae during an 11 month period but died because of progression of metastatic processes. We hypothesized that initial congestive heart failure had been a provocative factor for thromboembolic events from previous thrombus formation at the inferior vena cava.
Kinova
Elena
E
University Hospital Queen Giovanna Cardiology, Sofia, Bulgaria. ekinova@hotmail.com
Zlatareva
Naydenka
N
Goudev
Assen
A
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D004452:Echocardiography; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006325:Heart Atria; D006331:Heart Diseases / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D013927:Thrombosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014682:Vena Cava, Inferior; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced* / Q000150:complications
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil