Magnesium nitride as a convenient source of ammonia: preparation of primary amides.
The use of magnesium nitride (Mg 3N 2) as a convenient source of ammonia has been explored for the direct transformation of esters to primary amides. Methyl, ethyl, isopropyl, and tert-butyl esters are converted to the corresponding carboxamides in good yields (75-99%).
Veitch
Gemma E
GE
Department of Chemistry, Lensfield Road, University of Cambridge, Cambridge CB2 1EW, UK.
Bridgwood
Katy L
KL
Ley
Steven V
SV
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000641:Ammonia / Q000138:chemical synthesis* / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D017616:Magnesium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D000577:Amides; D004952:Esters; D017616:Magnesium Compounds; D000641:Ammonia; C532304:magnesium nitride