title: Structure and biosynthesis of norneolambertellin produced by Lambertella sp. 1346.
abstract: Norneolambertellin (1) was isolated from a mycoparasite Lambertella sp. 1346. Combined analysis of the NMR spectra and chemical shift prediction based on molecular orbital calculation successfully revealed a novel pyrano[3,2-c]chromene-2,5-dione structure, which was further confirmed by X-ray crystallographic analysis. Isotopomer distribution analysis of the sample, prepared under labeling conditions, deduced its biosynthetic pathway.
authors.affiliation: Department of Agriculture and Bioscience, Hirosaki University, 3-Bunkyo-cho, Hirosaki, Aomori 036-8561, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Murakami
authors.forename: Noboru
authors.initials: N
authors.lastname: Takada
authors.forename: Warren
authors.initials: W
authors.lastname: Hehre
authors.forename: Masaru
authors.initials: M
authors.lastname: Hashimoto
mesh_terms: D001203:Ascomycota / Q000378:metabolism*; D002244:Carbon / Q000737:chemistry; D002626:Chemistry, Pharmaceutical / Q000379:methods; D018360:Crystallography, X-Ray / Q000379:methods*; D015195:Drug Design; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007477:Ions; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D008956:Models, Chemical; D008968:Molecular Conformation; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D007477:Ions; D009281:Naphthalenes; D013141:Spiro Compounds; D002244:Carbon; C504281:lambertellin