Iterative molecular assembly based on the cation-pool method. Convergent synthesis of dendritic molecules.
An iterative method for molecular assembly has been developed based on the cation-pool method using (trimethylsilyl)diphenylmethane as a building block. The silyl group works as both an activating group of the benzene ring in the Friedel-Crafts type reaction and an electroauxiliary in the subsequent low temperature anodic oxidation to generate dendritic diarylcarbenium ions, which were well characterized by low-temperature NMR spectroscopy. The convergent synthesis of dendritic molecules has been achieved by repeating the sequence.
Nokami
Toshiki
T
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku, Kyoto 615-8510, Japan.
Ohata
Kousuke
K
Inoue
Masafumi
M
Tsuyama
Hiroaki
H
Shibuya
Akito
A
Soga
Kazuya
K
Okajima
Masayuki
M
Suga
Seiji
S
Yoshida
Jun-ichi
J
D001559:Benzhydryl Compounds / Q000737:chemistry*; D002412:Cations / Q000737:chemistry; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D001559:Benzhydryl Compounds; D002412:Cations; D050091:Dendrimers; C010129:diphenylmethane