Treatment recommendations for patients with common respiratory tract infections with variables indicative of treatment failure.
Treatment with an appropriate antimicrobial agent significantly decreases the bacterial burden and reduces the risk of a patient progressing to a more severe infection. When evaluating the use of antibiotics, practitioners should consider such factors as the local resistance patterns of common respiratory pathogens, the likelihood of infection with a resistant organism, and the potential for treatment failure. Recent antibiotic use is a risk factor for treatment failure. For patients with risk factors predictive of treatment failure, beta-lactams (usually in combination with a beta-lactamase inhibitor or a macrolide) and fluoroquinolones are most commonly recommended.
Basri
Raymond S
RS
New York Medical College, Valhalla, NY, USA.
Weiland
David A
DA
Ledgerwood
Greg L
GL
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D029481:Bronchitis, Chronic / Q000188:drug therapy / Q000382:microbiology; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D004334:Drug Administration Schedule; D016903:Drug Monitoring; D004363:Drug Utilization / Q000592:standards; D005194:Family Practice / Q000379:methods / Q000592:standards; D006801:Humans; D018579:Patient Selection; D011014:Pneumonia / Q000188:drug therapy / Q000382:microbiology; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D012307:Risk Factors; D012852:Sinusitis / Q000188:drug therapy / Q000382:microbiology; D017211:Treatment Failure
D000900:Anti-Bacterial Agents