title: Perspectives on hormone replacement therapy: the Women's Health Initiative and new observational studies sampling the overall population.
abstract: This commentary integrates the most recent information on coronary heart disease from the Women's Health Initiative (WHI) trial and our new large observational studies, which complement and expand the WHI results to the overall population. Breast and colon cancer findings are also considered.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Tannen
authors.forename: Mark G
authors.initials: MG
authors.lastname: Weiner
authors.forename: Dawei
authors.initials: D
authors.lastname: Xie
authors.forename: Kurt
authors.initials: K
authors.lastname: Barnhart
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology; D015331:Cohort Studies; D003110:Colonic Neoplasms / Q000209:etiology; D003327:Coronary Disease / Q000209:etiology*; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D011159:Population Surveillance; D017698:Postmenopause; D016032:Randomized Controlled Trials as Topic; D016387:Women's Health