title: Fluoride oral retention after professional topical application in children with caries activity: effect of the immediate water consumption.
abstract: OBJECTIVE
  Since there is no agreement about the time patients must refrain from drinking or eating after a professional application of acidulated phosphate fluoride (APF), the purpose of this study was to evaluate the effect of water consumption on fluoride in saliva.
  
  
  METHODS
  This blind randomized crossover in vivo study involved children who received a professional APF gel application followed by either drinking a glass of water (experimental group) or without rinsing, drinking, or eating (control group) for 2 hours. The nonstimulated saliva was collected at 0, 5, 15, 30, 60, and 120 minutes following the professional APF application. After a 7-day washout period, the control and treatment groups were switched.
  
  
  RESULTS
  There was a statistically significant difference in the fluoride retention between groups in the times 0 to 5 minutes (P<.05).
  
  
  CONCLUSIONS
  The data suggest that the recommendation of asking patients to refrain from drinking water for 30 minutes following the professional APF application is excessive and can be reduced to 15 minutes.
authors.affiliation: Faculty of Dentistry, Federal University of Maranhão, São Luís, Brazil.
authors.forename: Mariana de Figueiredo
authors.initials: Mde F
authors.lastname: Lopes
authors.forename: Juliana de Kássia Silva
authors.initials: Jde K
authors.lastname: Braga
authors.forename: Ana Emília Figueiredo
authors.initials: AE
authors.lastname: de Oliveira
authors.forename: Paulo Roberto Saraiva
authors.initials: PR
authors.lastname: Cavalcante
authors.forename: Cecilia Cláudia Costa
authors.initials: CC
authors.lastname: Ribeiro
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002648:Child; D018592:Cross-Over Studies; D003731:Dental Caries / Q000378:metabolism / Q000517:prevention & control*; D004326:Drinking / Q000502:physiology*; D004435:Eating / Q000502:physiology; D005260:Female; D005460:Fluorides, Topical / Q000493:pharmacokinetics* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012463:Saliva / Q000378:metabolism*; D016037:Single-Blind Method; D013997:Time Factors
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical; D000149:Acidulated Phosphate Fluoride