title: Extensive callosal infarction showing difficulty in knitting as an initial symptom.
abstract: A 66-year-old right-handed woman with type 2 diabetes mellitus was admitted to our hospital with progressive dysarthria and gait disturbance preceded by difficulty in knitting. Brain magnetic resonance imaging (MRI) showed a lesion involving the entire corpus callosum. Although tumor was considered in the differential diagnosis because of the atypical imaging findings, she was diagnosed with infarction based on clinical improvement after admission and sequential changes in MRI. We suggest that difficulty in knitting may be an important early manifestation of a callosal disconnection syndrome and that follow-up clinical and imaging examinations would contribute to confirmation of the diagnosis.
authors.affiliation: Department of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Koshigaya. keisuke@dokkyomed.ac.jp
authors.forename: Keisuke
authors.initials: K
authors.lastname: Suzuki
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Takiguchi
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Masayuki
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Koichi
authors.initials: K
authors.lastname: Hirata
authors.forename: Kenji
authors.initials: K
authors.lastname: Hara
authors.forename: Shiho
authors.initials: S
authors.lastname: Suzuki
authors.forename: Kohzo
authors.initials: K
authors.lastname: Takebayashi
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Aso
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Inukai
mesh_terms: D000368:Aged; D020520:Brain Infarction / Q000175:diagnosis* / Q000473:pathology* / Q000503:physiopathology; D003337:Corpus Callosum / Q000473:pathology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004401:Dysarthria / Q000503:physiopathology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D019957:Motor Skills Disorders / Q000209:etiology*; D013577:Syndrome; D013927:Thrombosis / Q000503:physiopathology