A novel placement method of the Bravo wireless pH monitoring capsule for measuring intragastric pH.
OBJECTIVE
The delivery system of the Bravo capsule was designed for placement on the esophagus. We evaluated the feasibility of our novel placement method of the Bravo capsule using a clip to monitor intragastric pH and to compare the accuracy of the Bravo wireless system to the traditionally used Slimline catheter-Mark III Digitrapper pH monitoring system.


METHODS
The Bravo capsule was placed by clip or conventional delivery system using suction on the gastric wall in 20 fasted subjects. A separate group of ten healthy volunteers underwent simultaneous intragastric pH monitoring for comparison of the two systems with meals.


RESULTS
Early dislodgment rate of the capsules was lower when placed using clipping (20%) than using conventional delivery system (70%) within 48 h after placement. We observed prominent movement of one catheter in the stomach during the study. Post-test calibration drifts of the catheters at pH 7.01 were significantly greater than those of the Bravo capsules (P = 0.02).


CONCLUSIONS
Our novel clipping method of the Bravo pH capsule placement provided accurate monitoring of intragastric pH with merits of tolerability, acid stability, and fixing position.
Chang
Jae Hyuck
JH
Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kangnam St. Mary's Hospital, The Catholic University of Korea, No. 505, Banpo-Dong, Seocho-Gu, Seoul, 137-040, South Korea.
Choi
Myung Gyu
MG
Yim
Dong-Seok
DS
Cho
Yu Kyung
YK
Park
Jae Myung
JM
Lee
In Seok
IS
Kim
Sang Woo
SW
Chung
In Sik
IS
D000328:Adult; D000368:Aged; D002404:Catheterization; D050782:Esophageal pH Monitoring; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D013270:Stomach / Q000737:chemistry; D055815:Young Adult