title: Primary leiomyosarcoma of the tibia--five years without recidivism.
abstract: Primary leiomyosarcoma of the bone is a rare malignancy. Clinical follow-up suggests that primary osseous leiomyosarcoma has an aggressive biologic behaviour with poor survival time. We report a case of primary leiomyosarcoma arising from the proximal metaphysis of the right tibia of a 55-year old woman with a long follow-up period, without recidivism. Primary leiomyosarcoma has to be considered as a differential diagnostic possibility in the case of bone tumours seen on routine initial plain radiographs as lytic lesions. If the tumour has been adequately excised at the time of diagnosis, as in the present case, with adjuvant therapy protocol, the long-term prognosis of such an aggressive tumour can be exceptionally good.
authors.affiliation: Orthopaedic Clinical Hospital, Lovran, Croatia. branko.sestan1@ri.htnet.hr
authors.forename: B
authors.initials: B
authors.lastname: Sestan
authors.forename: D
authors.initials: D
authors.lastname: Miletic
authors.forename: N
authors.initials: N
authors.lastname: Jonjic
authors.forename: I
authors.initials: I
authors.lastname: Rakovac
authors.forename: D
authors.initials: D
authors.lastname: Ekl
authors.forename: T
authors.initials: T
authors.lastname: Djapic
authors.forename: H
authors.initials: H
authors.lastname: Stalekar
mesh_terms: D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013977:Tibia / Q000473:pathology* / Q000601:surgery*