title: Hemorrhage into cystic vestibular schwannoma following stereotactic radiation therapy.
abstract: The occurrence of a hemorrhage into a vestibular schwannoma is a rare phenomenon. Several reports, however, indicate a risk profile for a subgroup of patients with vestibular schwannoma which show hypervascularity in the histopathological examination. Cystic formation, large size, mixed Antoni type and anticoagulation therapy seem to enhance the risk of tumor hemorrhage. We report on a patient with a large cystic vestibular schwannoma who died from fatal bleeding into the tumor 15 months following stereotactic radiation therapy. Since hemorrhage seems to be a relevant risk in large cystic vestibular schwannomas, a surgical treatment should be preferred whenever possible.
authors.affiliation: Neurochirurgische Klinik und Poliklinik, Universität Erlangen-Nürnberg, Erlangen, Germany. ganslandt@nch.imed.uni-erlangen.de
authors.forename: O
authors.initials: O
authors.lastname: Ganslandt
authors.forename: A
authors.initials: A
authors.lastname: Fahrig
authors.forename: C
authors.initials: C
authors.lastname: Strauss
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000209:etiology; D001523:Mental Disorders / Q000209:etiology; D009464:Neuroma, Acoustic / Q000150:complications / Q000601:surgery*; D010291:Paresis / Q000209:etiology; D011183:Postoperative Complications / Q000473:pathology*; D016634:Radiosurgery / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D014474:Unconsciousness / Q000209:etiology