title: Genetic diversity of Porphyromonas gingivalis isolates recovered from single "refractory" periodontitis sites.
abstract: Multilocus sequence typing and fimA genotyping were performed on Porphyromonas gingivalis isolates from 15 subjects with "refractory" periodontitis. Several sequence types were detected for most individual pockets. The variation indicated recombination at the recA and pepO genes. The prevalence of fimA genotypes II and IV confirmed their association with periodontitis.
authors.affiliation: Institute of Oral Biology, Faculty of Dentistry, University of Oslo, P.O. Box 1052, NO-0316 Oslo, Norway. morteene@odont.uio.no
authors.forename: Morten
authors.initials: M
authors.lastname: Enersen
authors.forename: Ingar
authors.initials: I
authors.lastname: Olsen
authors.forename: Dominique A
authors.initials: DA
authors.lastname: Caugant
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000235:genetics; D010450:Endopeptidases / Q000235:genetics; D036781:Fimbriae Proteins / Q000235:genetics; D005798:Genes, Bacterial; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D010514:Periodontal Pocket / Q000382:microbiology; D010518:Periodontitis / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D011938:Rec A Recombinases / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; C063055:fimbrillin; D036781:Fimbriae Proteins; D011938:Rec A Recombinases; D010450:Endopeptidases