[Use of topical voriconazole in Alternaria keratitis].
METHODS
A 38-year-old man with fungal Alternaria keratitis was referred from another hospital 25 days after post-traumatic penetrating keratoplastia surgery on his right eye. We commenced treatment with topical voriconazole and the condition resolved.


CONCLUSIONS
Fungal Alternaria keratitis is rare, and treatment is difficult because the clinical response does not correlate well with the antibiotic in vitro sensitivity of the fungus. Clinical cases need to be diagnosed and treated quickly if visual loss is to be avoided. The combination of topical and systemic voriconazole has been shown to be an effective treatment for this condition
De-Domingo-Barón
B
B
Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, España. bdedbar@yahoo.es
Rodríguez-Ares
T
T
Touriño-Peralba
R
R
Pardo-Sánchez
F
F
Romero-Jung
P
P
Barcia
M
M
D000284:Administration, Oral; D000328:Adult; D000528:Alternaria; D000935:Antifungal Agents / Q000008:administration & dosage*; D015821:Eye Infections, Fungal / Q000188:drug therapy* / Q000382:microbiology; D005131:Eye Injuries / Q000601:surgery; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000382:microbiology; D015948:Keratoplasty, Penetrating; D008297:Male; D009181:Mycoses / Q000188:drug therapy; D009883:Ophthalmic Solutions; D011743:Pyrimidines / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage*; D065819:Voriconazole
D000935:Antifungal Agents; D009883:Ophthalmic Solutions; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole