title: The use of Levosimendan for myocardiopathy due to acute Chagas' disease.
abstract: Acute Chagas' disease corresponds to the initial period of a Trypanosoma cruzi infection. Levosimendan is a positive inotropic drug with vasodilatory properties that is indicated for acute heart failure. We describe two cases of myocarditis due to acute Chagas' disease, resulting from oral intake of sugar cane juice infected with T. cruzi and resulting complications. Both developed acute decompensated heart failure refractory to Dobutamine. We describe for the first time in the medical literature the use of Levosimendan for myocarditis due to acute Chagas' disease, with excellent clinical and hemodynamic results.
authors.forename: Rafael
authors.initials: R
authors.lastname: de March Ronsoni
authors.forename: Rubens Vaz
authors.initials: RV
authors.lastname: Feijó
authors.forename: Luiz Henrique
authors.initials: LH
authors.lastname: Melo
authors.forename: Fabiano Luis
authors.initials: FL
authors.lastname: Schwingel
authors.forename: Wilson Jacob
authors.initials: WJ
authors.lastname: Filho
authors.forename: Renata Zomer
authors.initials: RZ
authors.lastname: de Albernaz Muniz
authors.forename: Sarah
authors.initials: S
authors.lastname: Weber
authors.forename: Adriana
authors.initials: A
authors.lastname: Moro
mesh_terms: D000208:Acute Disease; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D002598:Chagas Cardiomyopathy / Q000188:drug therapy*; D006801:Humans; D006835:Hydrazones / Q000627:therapeutic use*; D009205:Myocarditis / Q000188:drug therapy* / Q000469:parasitology; D011724:Pyridazines / Q000627:therapeutic use*; D000077464:Simendan
chemical_list: D002316:Cardiotonic Agents; D006835:Hydrazones; D011724:Pyridazines; D000077464:Simendan