title: Navigating the RNA folding landscape.
abstract: Analysis of individual RNA folding reactions reveals that, as in proteins, cooperative interactions selectively drive RNA toward its biologically active, native conformation. This new work establishes a platform for future investigations of the physical principles underlying the assembly of large RNA enzymes.
authors.forename: Ruben L
authors.initials: RL
authors.lastname: Gonzalez
mesh_terms: D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry; D020871:RNA Stability; D016337:RNA, Catalytic / Q000737:chemistry*
chemical_list: D016337:RNA, Catalytic; D012313:RNA