Chiral gamma-amino amide synthesis by heterobimetallic lanthanum/lithium/Pybox-catalyzed direct asymmetric mannich-type reactions of alpha-keto anilides.
Lu
Gang
G
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan.
Morimoto
Hiroyuki
H
Matsunaga
Shigeki
S
Shibasaki
Masakatsu
M
D000577:Amides / Q000737:chemistry*; D000813:Anilides / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
C530038:(4'S,5'S)-2,6-bis(4'-(triisopropylsilyl)oxymethyl-5'-phenyl-1',3'-oxazolin-2'-yl)pyridine; D000577:Amides; D000813:Anilides; D007659:Ketones; D010080:Oxazoles; D011725:Pyridines; D007811:Lanthanum; D008094:Lithium