Association of the BDNF Val66Met variation with obesity in women.
Brain-derived neurotrophic factor (BDNF) has been implied in the regulation of food intake. In the present study, we genotyped the Val66Met polymorphism in a Belgian cohort of 532 obese women and 197 healthy female controls and were, for the first time, able to show an association of the 66Met allele with obesity, at least in our female cohort.
Beckers
Sigri
S
Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium. sigri.beckers@ua.ac.be
Peeters
Armand
A
Zegers
Doreen
D
Mertens
Ilse
I
Van Gaal
Luc
L
Van Hul
Wim
W
D000293:Adolescent; D000328:Adult; D001530:Belgium; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics*; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D008875:Middle Aged; D020125:Mutation, Missense; D009765:Obesity / Q000235:genetics*; D011110:Polymorphism, Genetic; D044465:White People / Q000235:genetics
D019208:Brain-Derived Neurotrophic Factor