Serotypes and susceptibility of Streptococcus pneumoniae strains isolated from children in Mexico.
OBJECTIVE
To identify serotypes and susceptibility of S. pneumoniae strains from 48 children with invasive infections and 50 carriers.


METHODS
Typing was performed by the Quellung reaction and susceptibility by Kirby-Bauer and Etest according to CLSI standards.


RESULTS
Of 31 meningeal strains, serotypes 19F, 3, 6B, 14 and 23F were predominant. Resistance to penicillin and STX was 16 and 58%, respectively; of 17 invasive non-meningeal strains, serotypes 19F and 3 were predominant and resistance to penicillin and SXT was 0 and 82%, respectively; of carrier strains, serotypes 6A, 6B, 19F and 23F were predominant.


CONCLUSIONS
A 10-valent conjugate vaccine could offer a better coverage for meningeal strains.
Villaseñor-Sierra
Alberto
A
Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Mexico. avillase@prodigy.net.mx
Lomas-Bautista
Maricarmen
M
Aguilar-Benavides
Sergio
S
Martínez-Aguilar
Gerardo
G
D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008800:Mexico; D008826:Microbial Sensitivity Tests; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification