title: The European ACuteTox project: a modern integrative in vitro approach to better prediction of acute toxicity.
abstract: ACuteTox (optimization and prevalidation of an in vitro test strategy for predicting human acute toxicity) is an integrated European Union project under the Sixth Framework Programme with the aim of demonstrating that animal tests for acute systemic toxicity currently used for regulatory purposes could be replaced by a combination of alternative assays. Validated alternative test methods are urgently required for safety toxicology testing of chemicals, cosmetics, and drugs.
authors.affiliation: Expertrådet AB, Sollentuna, Sweden. cecilia.clemedson@expertradet.se
authors.forename: C
authors.initials: C
authors.lastname: Clemedson
mesh_terms: D005062:European Union; D006801:Humans; D007391:International Cooperation; D007928:Lethal Dose 50; D011237:Predictive Value of Tests; D023382:Toxicity Tests, Acute / Q000379:methods*