Effect of cerebronorm on energy metabolism and lipid peroxidation in rat brain during hypoxia.
Cerebronorm prevents de-energization of mitochondria, limitation of succinate- and NAD-dependent energy production, and oxidation-phosphorylation uncoupling and inhibits LPO processes in the brain of rats under conditions of hypoxia.
Vasilyev
K Yu
KY
Institute of Pharmacology, Siberian Division of Russian Academy of Medical Sciences, Tomsk.
Khazanov
V A
VA
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004734:Energy Metabolism / Q000187:drug effects / Q000502:physiology*; D000860:Hypoxia / Q000503:physiopathology*; D007290:Inosine Diphosphate / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D009536:Niacinamide / Q000494:pharmacology; D010085:Oxidative Phosphorylation / Q000187:drug effects; D051381:Rats; D012256:Riboflavin / Q000494:pharmacology; D019802:Succinic Acid / Q000494:pharmacology
D009536:Niacinamide; D007290:Inosine Diphosphate; D019802:Succinic Acid; D012256:Riboflavin