Cyanide poisoning in the post-transplantation patient-a cautionary tale.
There have been few reported cases of cyanide toxicity following treatment with sodium nitroprusside. We report on the case of a paediatric patient who had received sodium nitroprusside for intractable hypertension in the post-operative period, resulting in cyanide toxicity. Treatment with sodium thiosulphate, sodium nitrate and haemodialysis resulted in the elimination of cyanide from the circulation. The patient made a full recovery with no neurological sequelae.
Quinlan
Catherine
C
Paediatric Nephrology, Children's University Hospital, Temple Street, Dublin 1, Ireland. cathyquinlan@mac.com
Gill
Denis
D
Waldron
Mary
M
Awan
Atif
A
D000293:Adolescent; D003486:Cyanides / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D016030:Kidney Transplantation; D009599:Nitroprusside / Q000009:adverse effects* / Q000627:therapeutic use*; D011183:Postoperative Complications; D014665:Vasodilator Agents / Q000009:adverse effects / Q000627:therapeutic use
D003486:Cyanides; D014665:Vasodilator Agents; D009599:Nitroprusside