title: Food allergy: a clinician's criteria for including sera in a serum bank.
abstract: Safety assessment for genetically-engineered crop plants includes assessment for allergic responses. To facilitate this assessment, serum banks should contain well-characterised sera from patients with confirmed food allergies. A serum is defined as well-characterised if it is taken from a patient who has a convincing history of allergic responses to a known allergen or an allergen-containing food, a positive skin prick test (or elevated IgE response), and a positive response in a clinical food challenge.
authors.affiliation: Department of Dermatology, Allergy Unit, University Hospital Zürich, Gloriastrasse 31, CH 8091, Zürich, Switzerland. barbara.ballmer@usz.ch
authors.forename: B K
authors.initials: BK
authors.lastname: Ballmer-Weber
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Rivas
mesh_terms: D000485:Allergens / Q000276:immunology*; D001771:Blood Banks; D005512:Food Hypersensitivity / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D030841:Food, Genetically Modified; D006801:Humans; D007106:Immune Sera / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D030821:Plants, Genetically Modified / Q000276:immunology*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D012882:Skin Tests
chemical_list: D000485:Allergens; D007106:Immune Sera; D007073:Immunoglobulin E