o-Dihaloarenes as aryne precursors for nickel-catalyzed [2 + 2 + 2] cycloaddition with alkynes and nitriles.
o-Dihaloarenes acting as aryne precursors react with acetylenes and nitriles catalyzed by the NiBr(2)(dppe)/dppe/Zn system to give substituted naphthalene, phenanthridine or triphenylene derivatives depending on the reaction conditions in moderate to excellent yields with good tolerance of functional groups.
Hsieh
Jen-Chieh
JC
Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan. chcheng@mx.nthu.edu.tw
Cheng
Chien-Hong
CH