title: Comparison of groupings among members of the genus Aspergillus based on phylogeny and production of bioactive compounds.
abstract: Three hundred sixty-six Aspergillus strains preserved at the National Institute of Technology and Evaluation (NITE) were compared as to phylogenetic relationships (11 species-clusters) based on the DNA sequences of the D1/D2 domains of LSU rRNA and ITS regions, including the 5.8S rRNA and biological activities of their secondary metabolites. The results showed relatively well correlation between the phylogenetic distribution and the production of bioactive compounds, especially, antimicrobial activities.
authors.affiliation: NITE Biotechnology Development Center, Department of Biotechnology, National Institute of Technology and Evaluation, Chiba, Japan.
authors.forename: Kozue
authors.initials: K
authors.lastname: Anzai
authors.forename: Shinzo
authors.initials: S
authors.lastname: Mayuzumi
authors.forename: Takuji
authors.initials: T
authors.lastname: Nakashima
authors.forename: Hajime
authors.initials: H
authors.lastname: Sato
authors.forename: Shigeki
authors.initials: S
authors.lastname: Inaba
authors.forename: Ju-Young
authors.initials: JY
authors.lastname: Park
authors.forename: Natsumi
authors.initials: N
authors.lastname: Kuwahara
authors.forename: Rieko
authors.initials: R
authors.lastname: Suzuki
authors.forename: Noriko
authors.initials: N
authors.lastname: Utsumi
authors.forename: Fumie
authors.initials: F
authors.lastname: Yokoyama
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ohfuku
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Ando
mesh_terms: D001230:Aspergillus / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D004271:DNA, Fungal / Q000235:genetics; D010802:Phylogeny
chemical_list: D004271:DNA, Fungal