Programming DNA tube circumferences.
Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.
Yin
Peng
P
Department of Computer Science, California Institute of Technology, Pasadena, CA 91125, USA. py@caltech.edu
Hariadi
Rizal F
RF
Sahu
Sudheer
S
Choi
Harry M T
HM
Park
Sung Ha
SH
Labean
Thomas H
TH
Reif
John H
JH
D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D036103:Nanotechnology; D043942:Nanotubes; D009690:Nucleic Acid Conformation
D004277:DNA, Single-Stranded; D004247:DNA