Long-term outcome of parenthood project during in vitro fertilization and after discontinuation of unsuccessful in vitro fertilization.
OBJECTIVE
To explore the long-term outcome of patients who began IVF treatment by considering not only treatment outcome in the center but also the parenthood project outcome after discontinuation of unsuccessful IVF.


METHODS
Retrospective cohort follow-up study.


METHODS
Two French IVF centers.


METHODS
Seven hundred twenty-four patients who began IVF treatment in 1998.


METHODS
Postal and phone contacts with unsuccessful IVF patients.


METHODS
Long-term outcome of parenthood project.


RESULTS
Of the 724 patients, a minimum of 53% and a maximum of 81% finally succeeded in their parenthood project during or after IVF treatment (depending on the hypotheses that the 204 patients not contacted either failed or succeeded in their parenthood project). An intermediate hypothesis gave an estimation of 66% of patients finally succeeding in having a child (40% during IVF treatment in the center and 26% after). Achievement of the parenthood project after IVF discontinuation was due mainly to adoption of a child (46%) or a birth following a spontaneous pregnancy (42%).


CONCLUSIONS
Unsuccessful patients should not lose hope, because nearly half may subsequently succeed in having a child.
de La Rochebrochard
Elise
E
INSERM Unit 822, 82 rue du General Leclerc, Le Kremlin-Bicêtre Cedex, France. roche@ined.fr
Quelen
Céline
C
Peikrishvili
Rusudan
R
Guibert
Juliette
J
Bouyer
Jean
J
D000300:Adoption; D000328:Adult; D015331:Cohort Studies; D004624:Embryo Transfer / Q000379:methods; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods* / Q000523:psychology / Q000706:statistics & numerical data*; D005602:France; D006801:Humans; D007398:Interpersonal Relations; D007407:Interviews as Topic; D008297:Male; D010290:Parents / Q000523:psychology*; D011247:Pregnancy; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013689:Telephone; D017211:Treatment Failure; D016896:Treatment Outcome