title: Thymic Langerhans cell histiocytosis mimicking lymphoma.
abstract: Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal expansion of antigen presenting Langerhans cells. Different clinical features can be seen according to the involved organs and systems. Multisystem disease with organ dysfunction is more common in infants, whereas single system disease is usually observed in older children. The disease can affect any system or organ throughout the body. Thymus is a rarely involvement site reported in LCH and usually is accompanied by skin, bone or lung disease. Here we report a 12-year-old male with thymic involvement by LCH clinically mimicking lymphoma.
authors.affiliation: Department of Pediatric Oncology, Hacettepe University Institute of Oncology, Ankara, Turkey. drbegul@yahoo.com
authors.forename: Begül
authors.initials: B
authors.lastname: Yağci
authors.forename: Ali
authors.initials: A
authors.lastname: Varan
authors.forename: Aysegül
authors.initials: A
authors.lastname: Uner
authors.forename: Canan
authors.initials: C
authors.lastname: Akyüz
authors.forename: Münevver
authors.initials: M
authors.lastname: Büyükpamukçu
mesh_terms: D002637:Chest Pain; D002648:Child; D003937:Diagnosis, Differential; D004417:Dyspnea; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D013902:Radiography, Thoracic; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D015431:Weight Loss