Structural changes of poly-L-lysine in solution and lyophilized form.
Two structural changes of poly-L-lysine have been studied by various spectroscopic techniques; one is a structural change of a random coil sample in solution to a mixture of alpha-helix and beta-sheet during rapid freezing in the lyophilizing process, and the other is a pressure-induced structural change from an alpha-helix to a beta-sheet structure for a lyophilized sample.
Kambara
Ohki
O
Graduate School of Science and Technology, Kobe University, Nada, Kobe, Japan.
Tamura
Atsuo
A
Naito
Akira
A
Tominaga
Keisuke
K
D005612:Freeze Drying; D009682:Magnetic Resonance Spectroscopy; D011107:Polylysine / Q000737:chemistry*; D011487:Protein Conformation; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared
D012996:Solutions; D011107:Polylysine