[Placental mesenchymal dysplasia].
Placental mesenchymal dysplasia (PMD) is a recently described entity. Because of the presence of an embryo and a multicystic placenta, it has been initially misinterpreted as a partial mole on ultrasound as well as on gross examination. However, careful microscopic examination, cytogenetic analyses, molecular studies and follow-up of children allowed to better understand this placental abnormality, allowing an antenatal diagnosis. Our purpose was to describe ultrasonographic, macroscopic and microscopic features in PMD on the basis of a literature review and our own experience. We also detailed clinical presentation, complications of pregnancy and fetopathologic associations. We discussed ethiopathogenic hypotheses as well as differential diagnoses.
Allias
Fabienne
F
Service d'anatomie et cytologie pathologiques, hôpital de la Croix-Rousse, 93, Grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France. fabienne.allias-montmayeur@chu-lyon.fr
Lebreton
Frédérique
F
Collardeau-Frachon
Sophie
S
Vasiljevic
Alexandre
A
Rossignol
Sylvie
S
Massardier
Jérôme
J
Huissoud
Cyril
C
Devouassoux-Shisheboran
Mojgan
M
D002824:Chorionic Villi / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D047108:Embryonic Development; D005260:Female; D005313:Fetal Death / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006828:Hydatidiform Mole / Q000000981:diagnostic imaging / Q000473:pathology; D007231:Infant, Newborn; D008297:Male; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography