title: Cytokines as a key component of cancer-related inflammation.
abstract: Inflammatory conditions in some tissues increase the risk of cancer. Cytokines and chemokines are components of an intensive dialog promoting angiogenesis, metastasis, subversion of adaptive immunity and changing response to hormones and to chemotherapeutic agents. Cytokines involved in cancer-related inflammation represent a target for innovative diagnostic and therapeutic strategies, and a future challenge for scientists and clinicians.
authors.affiliation: Istituto Clinico Humanitas IRCCS, Via Manzoni 56, Rozzano, Milan, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Germano
authors.forename: Paola
authors.initials: P
authors.lastname: Allavena
authors.forename: Alberto
authors.initials: A
authors.lastname: Mantovani
mesh_terms: D018925:Chemokines / Q000502:physiology; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000502:physiology*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D007375:Interleukin-1 / Q000502:physiology; D015850:Interleukin-6 / Q000502:physiology; D009369:Neoplasms / Q000503:physiopathology*; D009389:Neovascularization, Pathologic; D017472:Receptors, Interleukin-1 / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology
chemical_list: D018925:Chemokines; D016207:Cytokines; D007375:Interleukin-1; D015850:Interleukin-6; D017472:Receptors, Interleukin-1; D014409:Tumor Necrosis Factor-alpha