title: Large B cell lymphoma--year by year.
abstract: Non Hodgkin's Lymphoma (NHL) comprises a group of lymphoproliferative disorders the frequency of which continues to rise. Although many classification systems exist for identifying specific histological subtypes, NHL is generally divided into indolent (low-grade) and aggressive (intermediate- and high-grade) forms. Large B Cell Lymphoma (LBCL) is one of the commonest aggressive NHLs. The aim of this review is to provide a general overview of NHL, its clinically practicable cellular classification, epidemiology and in depth overview of the evolution of treatment of LBCL during the past 5 years. Current guidelines from National Cancer Institute (NCI), USA and National Institute on Clinical Excellence (NICE), UK are mentioned and recommendations according to our own set-up are suggested.
authors.affiliation: Department of Oncology, Combined Military Hospital, Rawalpindi, Pakistan.
authors.forename: Abdus Samad
authors.initials: AS
authors.lastname: Syed
authors.forename: Fauzia Abdus
authors.initials: FA
authors.lastname: Samad
authors.forename: Mahmood
authors.initials: M
authors.lastname: ur Rahman
mesh_terms: D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy