title: Osteomalacic myopathy associated with coexisting coeliac disease and primary biliary cirrhosis.
abstract: OBJECTIVE
  To report a patient with coeliac disease (CD) associated with primary biliary cirrhosis (PBC) who presented with myopathy without classical symptoms of CD.
  
  
  METHODS
  A 42-year-old woman presented with inability to walk and marked loss of motor function. She had elevated liver enzymes with a cholestatic pattern. Antimitochondrial antibody M2 band, anti-endomysial antibody, antigliadin IgA and IgM were positive. Histopathologic findings of the liver revealed PBC and duodenal biopsy was consistent with CD. She was also found to have osteomalacia. She showed slow response to gluten-free diet, but accelerated full recovery with vitamin D replacement.
  
  
  CONCLUSIONS
  In PBC patients with subclinical CD and myopathy, vitamin D status can provide a basis for treatment.
authors.affiliation: Section of Rheumatology, Department of Internal Medicine, Gazi University, Ankara, Turkey. mehmetderyademirag@yahoo.com
authors.forename: Mehmet D
authors.initials: MD
authors.lastname: Demirag
authors.forename: Berna
authors.initials: B
authors.lastname: Goker
authors.forename: Seminur
authors.initials: S
authors.lastname: Haznedaroglu
authors.forename: Mehmet A
authors.initials: MA
authors.lastname: Ozturk
authors.forename: Tarkan
authors.initials: T
authors.lastname: Karakan
authors.forename: Reha
authors.initials: R
authors.lastname: Kuruoglu
mesh_terms: D000328:Adult; D002446:Celiac Disease / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D003937:Diagnosis, Differential; D055050:Diet, Gluten-Free; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000503:physiopathology; D009135:Muscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D010018:Osteomalacia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014807:Vitamin D / Q000627:therapeutic use*
chemical_list: D007070:Immunoglobulin A; D007075:Immunoglobulin M; D014807:Vitamin D