Concomitant coronary artery disease among Asian ischaemic stroke patients.
BACKGROUND
Coronary artery disease (CAD) is the leading cause of death following ischaemic stroke. We aimed to study the prevalence and associations of concomitant CAD among ischaemic stroke patients in Singapore.


METHODS
We prospectively studied 2686 consecutive Asian ischaemic stroke patients.


RESULTS
CAD was prevalent among 24% of the study patients. Older age, hypertension, diabetes, hyperlipidaemia, atrial fibrillation, large stroke and South Asian ethnicity were independently associated with CAD.


CONCLUSIONS
The variables found to be associated with CAD are known atherosclerotic risk factors (older age, hypertension, diabetes, hyperlipidaemia) or associations of cardioembolic stroke (atrial fibrillation, large stroke). The over-representation of South Asians with concomitant CAD is consistent with the high burden of CAD in this ethnic group.
De Silva
Deidre Anne
DA
Singapore General Hospital campus, National University of Singapore, Singapore. deidre.a.de.silva@sgh.com.sg
Woon
Fung Peng
FP
Moe
Kyaw Thu
KT
Chen
Christopher L H
CL
Chang
Hui Meng
HM
Wong
Meng Cheong
MC
D000368:Aged; D002545:Brain Ischemia / Q000150:complications* / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D012846:Singapore / Q000453:epidemiology; D020521:Stroke / Q000150:complications* / Q000453:epidemiology; D015996:Survival Rate; D013997:Time Factors