title: Corticospinal facilitation following prolonged proprioceptive stimulation by means of passive wrist movement.
abstract: The purpose of this study was to evaluate the delayed effects of repetitive sensory stimulation with passive wrist movement on corticospinal excitability of the forearm and hand musculature. Motor evoked potential responses to single and double pulse transcranial magnetic stimulation were recorded from the flexor carpi radialis, extensor carpi radialis, and the first dorsal interosseous muscles of the right limb. Data were collected before and after a 1 hour session of passive wrist movement (intervention group, n = 11) or after a same period of rest (control group, n = 9). Motor evoked potential size and area were analyzed to evaluate corticospinal excitability and short interval intracortical inhibition and facilitation. Training with passive movement resulted in a prolonged increase in corticospinal excitability in the flexor carpi radialis and extensor carpi radialis (until at least 1 hour postintervention), but did not evoke significant changes in the levels of short interval intracortical inhibition and facilitation. No such effects were noted in the control group or first dorsal interosseous muscle. Prolonged proprioceptive stimulation with passive wrist movement induces a delayed increase in corticospinal excitability of the forearm muscles. Accordingly, this intervention may promote motor cortical reorganization in the targeted muscles. Results show induced effects from passive movement training that may prove useful for neurorehabilitation therapies.
authors.affiliation: Motor Control Laboratory, Department of Biomedical Kinesiology, Group Biomedical Sciences, Katholieke Universiteit Leuven, Belgium. marc.mace@faber.kuleuven.be
authors.forename: Marc J-M
authors.initials: MJ
authors.lastname: Macé
authors.forename: Oron
authors.initials: O
authors.lastname: Levin
authors.forename: Kaat
authors.initials: K
authors.lastname: Alaerts
authors.forename: John C
authors.initials: JC
authors.lastname: Rothwell
authors.forename: Stephan P
authors.initials: SP
authors.lastname: Swinnen
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology*; D008297:Male; D009068:Movement / Q000502:physiology*; D018482:Muscle, Skeletal / Q000294:innervation / Q000502:physiology*; D010812:Physical Stimulation / Q000379:methods*; D011434:Proprioception / Q000502:physiology*; D011712:Pyramidal Tracts / Q000502:physiology*; D014955:Wrist Joint / Q000502:physiology*