[Bolus percutaneous ethanol injections in hepatocellular carcinoma--clinical results].
OBJECTIVE
To establish the effectiveness of large-volume percutaneous ethanol injection under general anesthesia (Shot-PEI) as a local method for destruction of large hepatocellular carcinoma (HCC).


METHODS
46 patients with 48 HCC were treated with Shot-PEI. 1-4 sessions per lesion were performed with 12-138 ml ethanol per session.


RESULTS
Complete destruction was achieved in 43.8% of the tumors. Major complications occurred in 10.9% of the patients. Local recurrences were 19%.


CONCLUSIONS
Shot-PEI is an effective method for destruction of large tumors and multiplies the therapeutic options in HCC.
Genov
I
I
Grigorov
N
N
Mitova
R
R
Golemanov
B
B
Dinkov
L
L
Donov
M
M
D000368:Aged; D000768:Anesthesia, General; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D000431:Ethanol / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014463:Ultrasonography
D000431:Ethanol