title: Leader genes: a data mining approach for molecular genomics.
abstract: A very large amount of genes is involved in each different cellular process, but only a few of them are supposed to play a central role. The leader gene approach is a data mining method, which may allow the identification of genes with potential highest importance in a given cellular process. We plan to use this method to shed new lights on molecular mechanisms of some complex oral diseases.
authors.affiliation: Department of Oral Pahology and Medicine, School of Dental Medicine, Universit of Genova, Genoa, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Giacomelli
authors.forename: Simone
authors.initials: S
authors.lastname: Marconcini
authors.forename: Giacomo
authors.initials: G
authors.lastname: Derchi
authors.forename: Antonio
authors.initials: A
authors.lastname: Barone
authors.forename: Ugo
authors.initials: U
authors.lastname: Covani
mesh_terms: D002453:Cell Cycle; D005796:Genes; D023281:Genomics / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000235:genetics; D016247:Information Storage and Retrieval; D009059:Mouth Diseases / Q000235:genetics*; D010012:Osteogenesis / Q000235:genetics; D012871:Skin Diseases / Q000235:genetics; D013601:T-Lymphocytes / Q000166:cytology