title: Efficacy and safety of innovative cosmeceuticals.
abstract: The research and development of cosmeceuticals is booming in recent years. Many substances, either from botanical, animal, or chemically synthesized sources, are tested or investigated as the active ingredients in cosmeceuticals. The interactions between cosmeceuticals and skin are complex, depending on the specific composites in cosmeceutical products, condition of the skin or general health status of a subject, and the environment where the action occurs. As such, careful preclinical or clinical evaluation of efficacy and safety is a prerequisite for the development of a specific cosmeceutical product. This article reviews some of the ingredients that are currently in use or might be potential candidates in cosmeceuticals of different categories.
authors.affiliation: Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, China.
authors.forename: Xing-Hua
authors.initials: XH
authors.lastname: Gao
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Huachen
authors.initials: H
authors.lastname: Wei
authors.forename: Hong-Duo
authors.initials: HD
authors.lastname: Chen
mesh_terms: D000818:Animals; D003358:Cosmetics / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D010936:Plant Extracts / Q000627:therapeutic use; D015595:Skin Aging / Q000187:drug effects; D012880:Skin Pigmentation / Q000187:drug effects; D013473:Sunscreening Agents / Q000627:therapeutic use
chemical_list: D003358:Cosmetics; D003879:Dermatologic Agents; D010936:Plant Extracts; D013473:Sunscreening Agents