title: Different inflammatory reactions to vitamin D3 among the lateral, third and fourth ventricular choroid plexuses of the rat.
abstract: The four choroid plexuses in the brain ventricles are not identical, but differences among them have rarely been studied. The present work concerns the inflammatory and hemorrhagic choroid plexitis produced in Lewis rats by a single gavage of cholecalciferol (vitamin D(3)) or related steroids with vitamin D activity. Plexitis was very severe in the fourth ventricular plexus, somewhat less severe in the lateral ventricular plexuses, and almost absent in the third ventricular plexus. These findings were compared to the scanty data from the literature on differences among the plexuses.
authors.affiliation: Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA. levines@NKI.RFMH.Org
authors.forename: Seymour
authors.initials: S
authors.lastname: Levine
authors.forename: Arthur
authors.initials: A
authors.lastname: Saltzman
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Ginsberg
mesh_terms: D000818:Animals; D002552:Cerebral Ventricles / Q000473:pathology*; D002762:Cholecalciferol / Q000009:adverse effects*; D002831:Choroid Plexus / Q000378:metabolism*; D005260:Female; D007249:Inflammation / Q000473:pathology*; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D012720:Severity of Illness Index; D014815:Vitamins / Q000009:adverse effects*
chemical_list: D014815:Vitamins; D002762:Cholecalciferol