title: Myocardial infarction and arterial thrombosis in identical newborn twins with homozygosity for the PAI-1 4 G/5 G polymorphism.
abstract: Myocardial infarction in the perinatal period, in the absence of congenital heart disease or coronary artery lesions, is rare. The most common etiology described are the thromboembolism and perinatal asphyxia. We report a case of monozygotic twins who developed, after birth, acute vascular events and both had PAI-1 4G/4G homozygosity.
authors.forename: Vittoria
authors.initials: V
authors.lastname: De Lucia
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Andreassi
authors.forename: Laura
authors.initials: L
authors.lastname: Sabatini
authors.forename: Lamia
authors.initials: L
authors.lastname: Ait-Ali
authors.forename: Isabella
authors.initials: I
authors.lastname: Spadoni
authors.forename: Sandra
authors.initials: S
authors.lastname: Giusti
mesh_terms: D000328:Adult; D004200:Diseases in Twins / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D006720:Homozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000235:genetics*; D017395:Plasminogen Activator Inhibitor 1 / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D013927:Thrombosis / Q000175:diagnosis / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*
chemical_list: D017395:Plasminogen Activator Inhibitor 1; C051321:SERPINE1 protein, human