Characterization of microcalcification: can digital monitor zooming replace magnification mammography in full-field digital mammography?
The aim of this study was to compare the diagnostic accuracy and image quality of microcalcifications in zoomed digital contact mammography with digital magnification mammography. Three radiologists with different levels of experience in mammography reviewed 120 microcalcification clusters in 111 patients with a full-field digital mammography system relying on digital magnification mammogram (MAG) images and zoomed images from contact mammography (ZOOM) using commercially available zooming systems on monitors. Each radiologist estimated the probability of malignancy and rated the image quality and confidence rate. Performance was evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and receiver operating characteristic (ROC) analysis. All three radiologists rated MAG images higher than ZOOM images for sensitivity with statistical significance (average value, 92% vs. 87%, P<0.05) and performance by ROC analysis improved with MAG imaging. The confidence rate for diagnosis decision and the assessment of lesion characteristics were also better in MAG images than in ZOOM images with statistical significance (P<0.0001). Digital magnification mammography can enhance diagnostic performance when characterizing microcalcifications. Images zoomed from digital contact mammography cannot serve as an alternative to direct magnification digital mammography.
Kim
Min Jung
MJ
Department of Radiology, Research Institute of Radiological Science, Yonsei University Health System, 134 Shinchon-dong, Seodaemoon-gu, Seoul, South Korea, 120-752.
Kim
Eun-Kyung
EK
Kwak
Jin Young
JY
Son
Eun Ju
EJ
Youk
Ji Hyun
JH
Choi
Seon Hyeong
SH
Han
Mooyoung
M
Oh
Ki Keun
KK
D001706:Biopsy; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis*; D002114:Calcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D055088:Early Detection of Cancer; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008327:Mammography / Q000379:methods*; D008495:Medical Oncology / Q000379:methods; D015233:Models, Statistical; D012372:ROC Curve; D011871:Radiology / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity