title: [Adalimumab: the molecule and manufacturing procedure].
abstract: Adalimumab is a fully human monoclonal antibody targeted toward tumor necrosis factor alpha (TNF-alpha). TNF-alpha is proinflammatory cytokine involved in the pathogenesis of many inflammatory diseases, as the psoriasis. The production process of adalimumab is complex and it is based in the called phague display technology.
authors.affiliation: Servicio de Dermatología. Hospital de Cruces. Cruces (Vizcaya). España. ZURINE.MARTINEZDELAGRANALVAREZDEARCAYA@osakidetza.net
authors.forename: Z
authors.initials: Z
authors.lastname: Martínez de Lagrán
authors.forename: S
authors.initials: S
authors.lastname: Pérez-Barrio
authors.forename: J L
authors.initials: JL
authors.lastname: Díaz-Pérez
mesh_terms: D000068879:Adalimumab; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D061067:Antibodies, Monoclonal, Humanized; D001435:Bacteriophages / Q000378:metabolism*; D001709:Biotechnology / Q000379:methods; D006801:Humans
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068879:Adalimumab