title: Comparative study of pharmacological activity of afala on the model of hormone-induced prostatitis in rats.
abstract: Afala (ultralow-dose antibodies to prostate-specific antigen) injected for 60 days to rats with hormone-induced prostatitis caused by sulpiride prevented the development of prostatic hyperplasia and reduced the severity of histological changes. The effect of Afala was superior to that of the reference drug (Serenoa repens extract).
authors.affiliation: Materia Medical Holding, Moscow. savelievakv@materiamedica.ru
authors.forename: K V
authors.initials: KV
authors.lastname: Savelieva
authors.forename: T G
authors.initials: TG
authors.lastname: Borovskaya
authors.forename: I A
authors.initials: IA
authors.lastname: Kheyfets
authors.forename: J L
authors.initials: JL
authors.lastname: Dugina
authors.forename: S A
authors.initials: SA
authors.lastname: Sergeeva
authors.forename: O I
authors.initials: OI
authors.lastname: Epstein
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000494:pharmacology*; D004195:Disease Models, Animal; D007124:Immunoenzyme Techniques; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology; D011388:Prolactin / Q000097:blood; D011467:Prostate / Q000187:drug effects / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000276:immunology*; D011470:Prostatic Hyperplasia / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy; D011472:Prostatitis / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D051381:Rats; D028024:Serenoa / Q000737:chemistry; D013469:Sulpiride
chemical_list: D000906:Antibodies; D010936:Plant Extracts; C533336:afala; D013469:Sulpiride; D011388:Prolactin; D017430:Prostate-Specific Antigen