Multi-vicinal fluoroalkanes: a new class of organofluorine compounds.
"Multi-vicinal fluoroalkanes" are straight-chain alkanes in which each adjacent carbon atom is bonded to one fluorine atom. Such molecules may be regarded as intermediate in structure between alkanes and perfluoroalkanes. The alternate fluoromethylene groups also generate stereogenic centres, which need to be controlled during synthesis. This review will describe our recent progress in the preparation of such single isomer motifs and the study of the conformational behaviour of this new class of organofluorine compounds.
Hunter
Luke
L
Centre for Biomolecular Sciences and School of Chemistry, University of St Andrews, St Andrews, United Kingdom.
O'Hagan
David
D
D000473:Alkanes / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry* / Q000145:classification*; D007536:Isomerism; D015394:Molecular Structure
D000473:Alkanes; D006845:Hydrocarbons, Fluorinated