Enantioselective rhodium-catalysed 1,4-additions of 2-heteroarylzinc donors using Me-DUPHOS.
The enantioselective 1,4-addition of 2-(substituted)thienylzinc and 2-furanylzinc reagents has been achieved (up to 99 : 1 er) using a complex derived from [Rh(C(2)H(4))(2)Cl](2) and Me-DUPHOS.
Le Nôtre
Jérôme
J
Department of Chemistry, University of Bath, Claverton Down, Bath, UK.
Allen
Joseph C
JC
Frost
Christopher G
CG