[A cause of intracerebral calcifications that should be known: pseudohypoparathyroidism Ib].
In children, pseudohypoparathyroidism (PHP) is a rare but classical cause of basal ganglia calcifications. It is caused by resistance to parathormone (PTH). Hypocalcemia, which may be symptomatic, is its main feature. We report the case of a 13-year-old boy, affected by type Ib PHP revealed by hypocalcemia and seizures, with basal ganglia calcifications on the CT scan. We describe the characteristics of the 2 main types of PHP and emphasize the search for this disease when basal ganglia calcifications are discovered, even fortuitously, on a cerebral CT scan.
Faissolle
P
P
Service de pédiatrie, hôpital l'Archet II, route Saint-Antoine-de-Ginestière, 06200 Nice, France. pfaissolle@free.fr
Wagner-Mahler
K
K
Mas
J-C
JC
Moreigne
M
M
Khalfi
A
A
Léonetti
V
V
Silvy
M
M
Barlier
A
A
Giudicelli
H
H
D000293:Adolescent; D001480:Basal Ganglia Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D008297:Male; D011547:Pseudohypoparathyroidism / Q000175:diagnosis*; D011859:Radiography; D012640:Seizures / Q000209:etiology