title: Effects of Mg-ATP on the flavonoid production in the Scutellaria baicalensis Georgii suspension cultures.
abstract: This work focused on the cultivation of S. baicalensis Georgii in vitro cultures and on the possibilities of increasing the production of secondary metabolites in these cultures. The aim of the Sstudy was to determine whether the baicalin transport through vacuolar membrane is dependent on the presence of Mg-ATP. Our results showed that Mg-ATP had a significant effect on the ratio of baicalin and baicalein content and on the transport speed of these flavonoids. Therefore, the transport mechanism for baicalin are probably some of the MRP proteins which are the subfamily of the ABC transporte
authors.affiliation: Charles University in Prague, Faculty of Pharmacy, Department of Pharmacognosy.
authors.forename: Z
authors.initials: Z
authors.lastname: Krsková
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: J
authors.initials: J
authors.lastname: Pec
authors.forename: J
authors.initials: J
authors.lastname: Dusek
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology*; D002478:Cells, Cultured; D044950:Flavanones / Q000096:biosynthesis*; D005419:Flavonoids / Q000096:biosynthesis*; D006861:Hydrogen Peroxide / Q000494:pharmacology; D008751:Methylene Blue / Q000494:pharmacology; D018517:Plant Roots; D031364:Scutellaria baicalensis / Q000378:metabolism*
chemical_list: D044950:Flavanones; D005419:Flavonoids; C038044:baicalin; C006680:baicalein; D000255:Adenosine Triphosphate; D006861:Hydrogen Peroxide; D008751:Methylene Blue