An antifungal property of crude plant extracts from Anogeissus leiocarpus and Terminalia avicennioides.
Chloroform, ethanolic, methanolic, ethyl acetate and aqueous root extracts of Anogeissus leiocarpus and Terminalia avicennioides were investigated in vitro for antifungal activities against Aspergillus niger, Aspergillus fumigatus, Penicillium species, Microsporum audouinii and Trichophyton rubrum using radial growth technique. The plant extracts inhibited the growth of all the test organisms. The minimum inhibitory concentration (MIC) of the extracts ranged between 0.03 microg/ml and 0.07 microg/ml while the minimum fungicidal concentration ranged between 0.04 microg/ml and 0.08 microg/ml. Anogeissus leiocarpus appears to be more effective as an antifungal agent than Terminalia avicennioides. Ethanolic extracts of the two plant roots were more effective than the methanolic, chloroform, or aqueous extracts against all the test fungi.
Mann
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Department of Science Laboratory Technology, The Federal Polytechnic, P.M.B. 55, Bida, Niger State, Nigeria. abdumann@yahoo.com
Banso
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Clifford
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D000935:Antifungal Agents / Q000494:pharmacology*; D029764:Combretaceae; D006801:Humans; D016488:Medicine, African Traditional; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots
D000935:Antifungal Agents; D010936:Plant Extracts