title: Optimization of data-acquistion rates in time-correlated single-photon fluorimetry.
abstract: Four different operating configurations of a time-to-amplitude converter were examined for performance in the time-correlated single-photon fluorimetric experiment. Parameters considered were the intensity/count linearity, maximum data rate, and decay distortion. The inverted configuration with an interactive source was optimum. This arrangement combined total linearity with a 37-kHz conversion rate and did not distort the fluorescence decay. In addition, the pulse-height analyzer could severely limit the overall system data rate and could destroy the TAC intensity/count linearity.
authors.affiliation: General Chemistry Division, Lawrence Livermore Laboratory, University of California, Livermore, California 94550Department of Chemistry, Purdue University, West Lafayette, Indiana 47907.
authors.forename: G R
authors.initials: GR
authors.lastname: Haugen
authors.forename: B W
authors.initials: BW
authors.lastname: Wallin
authors.forename: F E
authors.initials: FE
authors.lastname: Lytle