Allergen structures and biologic functions: the cutting edge of allergy research.
Studies of structure and function of allergens using state-of-the-art technologies have led to a better understanding of allergenicity, including aspects related to cross-reactivity, allergen nomenclature, and the identification of antigenic determinants. This information is being applied to the design and production of allergy vaccines, some of which already have proven efficacy and safety in clinical trials.
Pomés
Anna
A
Indoor Biotechnologies, 1216 Harris Street, Charlottesville, VA 22903, USA. apomes@inbio.com
D000485:Allergens / Q000737:chemistry / Q000276:immunology*; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003429:Cross Reactions; D003888:Desensitization, Immunologic; D018604:Epitope Mapping; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology* / Q000628:therapy; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D000485:Allergens; D000939:Epitopes; D007073:Immunoglobulin E