A combined reflectometry and quartz crystal microbalance with dissipation setup for surface interaction studies.
We have developed an instrument for surface interaction studies, which combines a newly invented four detector optical reflectometry setup with quartz crystal microbalance with dissipation (QCM-D) monitoring. The design is such that data from both techniques can be obtained simultaneously on the same sensor surface, with the same signal-to-noise ratio and time resolution, as for the individual techniques. In addition, synchronized information about structural transformations, molecular mass, and the hydration of thin films on solid surfaces can be obtained on the same specimen, as validated by monitoring the formation of supported lipid bilayers on a silica-coated QCM sensor surface. We emphasize that the optical (molecular) mass can be separated from the acoustic mass including hydrodynamically coupled solvent, which means, in turn, that the amount of solvent sensed by the QCM-D technique can be dynamically resolved during adsorption processes. In addition, the advantage/necessity to use four, compared to two, detector reflectometry is emphasized.
Wang
Guoliang
G
Chemical Physics Group, Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden. guowa@fy.chalmers.se
Rodahl
Michael
M
Edvardsson
Malin
M
Svedhem
Sofia
S
Ohlsson
Gabriel
G
Höök
Fredrik
F
Kasemo
Bengt
B
D000162:Acoustics; D000327:Adsorption; D003460:Crystallization; D004563:Electrochemistry; D004867:Equipment Design; D007700:Kinetics; D007834:Lasers; D008051:Lipid Bilayers / Q000737:chemistry*; D015233:Models, Statistical; D010783:Photometry / Q000295:instrumentation* / Q000379:methods; D011791:Quartz / Q000737:chemistry*; D012542:Scattering, Radiation; D012997:Solvents; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
D008051:Lipid Bilayers; D012997:Solvents; D011791:Quartz; D014025:Titanium