title: Tooth size patterns in patients with hypodontia and supernumerary teeth.
abstract: OBJECTIVE
  Anomalies of tooth number may not be isolated conditions but may have wider associations in the development of the dentition including tooth size. This study aimed to examine links between hypodontia, supernumerary teeth and crown size, considering the effect on the development of the whole dentition and so increase understanding of the aetiology of these conditions.
  
  
  RESULTS
  The patients, who were all of European ancestry, were 60 young adults (30 males and 30 females) with hypodontia and 60 age and sex matched controls together with 60 young adults (39 males and 21 females) with supernumerary teeth and 60 age and sex matched controls. Hand measurements of mesiodistal and buccolingual dimensions were made of the teeth on dental study models using Mitutoyo electric callipers. The mean value of two measurements was used and intra-operator and inter-operator reliability determined. Patients with hypodontia had smaller teeth than the control group and this difference was statistically significant (p<0.05) for all teeth except the MD dimensions of 13, 23, 24 and 44. The difference in size was greatest for the BL dimensions in hypodontia patients. Further, the greater the number of missing teeth the smaller the tooth size. The hypodontia patients also showed higher variability in tooth dimensions than the control group. Patients with supernumerary teeth had larger teeth than the controls, with the greatest differences in the MD dimensions. In both hypodontia and supernumerary patients the differences in tooth size were generalised throughout the dentition.
  
  
  CONCLUSIONS
  In anomalies of tooth number the size of teeth is also involved. In patients with hypodontia and supernumerary teeth the crown size of the whole dentition is affected. These findings are compatible with a multifactorial aetiology of these conditions.
authors.affiliation: International Collaborating Centre in Oro-facial Genetics and Development, University of Liverpool, School of Dental Sciences, Daulby Street, Liverpool L69 3GN, UK. a.h.brook@liverpool.ac.uk
authors.forename: A H
authors.initials: AH
authors.lastname: Brook
authors.forename: R C
authors.initials: RC
authors.lastname: Griffin
authors.forename: R N
authors.initials: RN
authors.lastname: Smith
authors.forename: G C
authors.initials: GC
authors.lastname: Townsend
authors.forename: G
authors.initials: G
authors.lastname: Kaur
authors.forename: G R
authors.initials: GR
authors.lastname: Davis
authors.forename: J
authors.initials: J
authors.lastname: Fearne
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000848:Anodontia / Q000473:pathology*; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D003765:Models, Dental; D009811:Odontometry; D015203:Reproducibility of Results; D014096:Tooth, Supernumerary / Q000473:pathology*