title: [Relevance of septal hypokinesia as a finding in myocardial perfusion gated-SPECT].
abstract: OBJECTIVE
  To identify septal hypokinesia (SH) with signs of right ventricular (RV) overload.
  
  
  METHODS
  Prospective study of consecutive patients divided into cases with SH (n = 39) and controls without SH (n = 27). Subjects with septal perfusion defects and alterations in conduction were excluded. Images were obtained after injection of 20 mCi (740 MBq) of technetium tracer. The perfusion and septal mobility, RV and left ventricle values were quantified and other clinical parameters were obtained. Multivariate non-parametric tests and Pearson's correlation tests were applied.
  
  
  RESULTS
  RV perfusion was higher in the case group (31.7 % vs 27.5 %, p = 0.012). 35.9 % of cases had undergone cardiac surgery (CS) in the past. A higher number of subjects with valve diseases (VD) was found in the case group (23.1 % vs 3.7 %, p = 0.031); the same occurred with smoking (46.2 % in cases vs. 11.1 % in controls, p = 0.05). Correlation was obtained between septal mobility and RV perfusion (-0.374, p = 0.015 bilateral), and between mobility of the septum and the RV (0.299, p = 0.015 unilateral).
  
  
  CONCLUSIONS
  This test has been scarcely applied in RV pathology; this entity has great repercussion on the prognosis of patients with heart failure. These findings may clarify certain aspects of its physiopathology.
  
  
  CONCLUSIONS
  According to our study, SH is associated with the degree of RV perfusion and mobility, as well as the presence of history of CS, VD and smoking.
authors.affiliation: Servicio de Medicina Nuclear, Hospital General Universitario Gregorio Marañón, Madrid, España. jalonso.hgugm@salud.madrid.org
authors.forename: J C
authors.initials: JC
authors.lastname: Alonso Farto
authors.forename: A
authors.initials: A
authors.lastname: Rotger
authors.forename: S R
authors.initials: SR
authors.lastname: Martínez de Llano
authors.forename: F
authors.initials: F
authors.lastname: Jiménez
authors.forename: R
authors.initials: R
authors.lastname: Hernández
authors.forename: P
authors.initials: P
authors.lastname: Domínguez
authors.forename: J M
authors.initials: JM
authors.lastname: Pérez Vázquez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001145:Arrhythmias, Cardiac / Q000000981:diagnostic imaging*; D055426:Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; D016022:Case-Control Studies; D005260:Female; D006346:Heart Septum / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D011446:Prospective Studies