Intracerebral haemorrhage in primary and metastatic brain tumours.
Intracerebral haemorrhage may both be a presenting manifestation in unrecognised brain tumour or--more frequently--take place in the disease course of known/suspected brain tumour due to diagnostic/therapeutic procedures, including biopsy, locoregional treatments and anti-angiogenic therapies. Apart from the difficulties inherent to accurate neuroradiological diagnosis in selected cases with small tumour volume, the main clinical problem that neurologists face is represented by decision making in prophylaxis/treatment of venous thromboembolism in these patients. These points are briefly discussed and available evidence on the last point is commented on.
Salmaggi
Andrea
A
Fondazione IRCCS Istituto Neurologico C. Besta, Via Celoria 11, 20133, Milan, Italy. salmaggi@istituto-besta.it
Erbetta
Alessandra
A
Silvani
Antonio
A
Maderna
Emanuela
E
Pollo
Bianca
B
D020533:Angiogenesis Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000098:blood supply* / Q000150:complications* / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology* / Q000503:physiopathology*; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D003952:Diagnostic Imaging; D006801:Humans; D018570:Risk Assessment; D054556:Venous Thromboembolism / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control
D020533:Angiogenesis Inhibitors; D000925:Anticoagulants; D000970:Antineoplastic Agents