title: Comment on "Lowpenetrant  RB allele in  small-cell cancer shows  geldanamycin instability  and discordant expression  with mutant ras" by Park  et al.
authors.forename: J William
authors.initials: JW
authors.lastname: Harbour
mesh_terms: D000483:Alleles; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D016227:Benzoquinones / Q000494:pharmacology* / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism; D015972:Gene Expression Regulation, Neoplastic; D016161:Genes, Retinoblastoma; D011905:Genes, ras; D006801:Humans; D047029:Lactams, Macrocyclic / Q000494:pharmacology* / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism; D018832:Molecular Chaperones / Q000378:metabolism / Q000502:physiology; D050505:Mutant Proteins / Q000235:genetics / Q000378:metabolism*; D019683:Penetrance; D011489:Protein Denaturation / Q000187:drug effects; D017510:Protein Folding
chemical_list: D000903:Antibiotics, Antineoplastic; D016227:Benzoquinones; D047029:Lactams, Macrocyclic; D018832:Molecular Chaperones; D050505:Mutant Proteins; C001277:geldanamycin