Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007.
Zika virus (ZIKV) is a mosquito-borne flavivirus first isolated in Uganda from a sentinel monkey in 1947. Mosquito and sentinel animal surveillance studies have demonstrated that ZIKV is endemic to Africa and Southeast Asia, yet reported human cases are rare, with <10 cases reported in the literature. In June 2007, an epidemic of fever and rash associated with ZIKV was detected in Yap State, Federated States of Micronesia. We report the genetic and serologic properties of the ZIKV associated with this epidemic.
Lanciotti
Robert S
RS
Diagnostic and Reference Laboratory, Arbovirus Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA. rsl2@cdc.gov
Kosoy
Olga L
OL
Laven
Janeen J
JJ
Velez
Jason O
JO
Lambert
Amy J
AJ
Johnson
Alison J
AJ
Stanfield
Stephanie M
SM
Duffy
Mark R
MR
D000914:Antibodies, Viral / Q000097:blood; D001483:Base Sequence; D004196:Disease Outbreaks; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008849:Micronesia / Q000453:epidemiology; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012698:Serologic Tests; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification; D000071243:Zika Virus Infection / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012367:RNA, Viral