title: PCR-like cascade reactions in the context of an allosteric enzyme mimic.
abstract: A supramolecular allosteric catalyst that exhibits a PCR-like cascade reaction is reported. The complex is triggered by a reaction with an acetate ion, which turns on a catalytic cascade that exponentially increases acetate ion concentration through an acyl transfer reaction.
authors.affiliation: Department of Chemistry and the International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.
authors.forename: Hyo Jae
authors.initials: HJ
authors.lastname: Yoon
authors.forename: Chad A
authors.initials: CA
authors.lastname: Mirkin
mesh_terms: D000085:Acetates / Q000737:chemistry; D040761:Biomimetic Materials / Q000737:chemistry*; D002384:Catalysis; D004247:DNA / Q000032:analysis / Q000737:chemistry; D004259:DNA-Directed DNA Polymerase / Q000737:chemistry / Q000378:metabolism; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D017553:Phosphorus Compounds / Q000737:chemistry; D016133:Polymerase Chain Reaction; D012238:Rhodium / Q000737:chemistry; D013457:Sulfur Compounds / Q000737:chemistry
chemical_list: D000085:Acetates; D017553:Phosphorus Compounds; D013457:Sulfur Compounds; D004247:DNA; D012238:Rhodium; D004259:DNA-Directed DNA Polymerase