Leader genes: a data mining approach for molecular genomics.
A very large amount of genes is involved in each different cellular process, but only a few of them are supposed to play a central role. The leader gene approach is a data mining method, which may allow the identification of genes with potential highest importance in a given cellular process. We plan to use this method to shed new lights on molecular mechanisms of some complex oral diseases.
Giacomelli
Luca
L
Department of Oral Pahology and Medicine, School of Dental Medicine, Universit of Genova, Genoa, Italy.
Marconcini
Simone
S
Derchi
Giacomo
G
Barone
Antonio
A
Covani
Ugo
U
D002453:Cell Cycle; D005796:Genes; D023281:Genomics / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000235:genetics; D016247:Information Storage and Retrieval; D009059:Mouth Diseases / Q000235:genetics*; D010012:Osteogenesis / Q000235:genetics; D012871:Skin Diseases / Q000235:genetics; D013601:T-Lymphocytes / Q000166:cytology