title: Motivational interviewing for modifying diabetes risk: a randomised controlled trial.
abstract: BACKGROUND
  Around 10-15% of adults aged over 40 years have pre-diabetes, which carries a high risk of progression to type 2 diabetes. Intensive lifestyle intervention reduces progression by as much as 58%. However, the cost and personnel requirements of these interventions are major obstacles to delivery in NHS primary care.
  
  
  OBJECTIVE
  To assess the effectiveness of a low-cost intervention, delivered in primary care by non-NHS staff, to reduce the risk of diabetes through weight loss and physical activity.
  
  
  METHODS
  Pragmatic single-blind randomised controlled trial with researchers and statistician blinded to group allocation.
  
  
  METHODS
  UK primary care.
  
  
  METHODS
  One-hundred and forty-one participants with a body mass index of 28 kg/m2 or more, but without diabetes or heart disease, received either information leaflets or individual behavioural counselling using motivational interviewing techniques. The intervention was delivered by five counsellors recruited from the local community. The primary outcomes were the proportions of participants meeting predefined targets for weight loss (5%) and moderate physical activity (150 minutes/week) after 6 months.
  
  
  RESULTS
  Using intention-to-treat analysis, more people in the intervention group achieved the weight-loss target (24% versus 7% for controls; odds ratio [OR]=3.96; 95% confidence interval [Cl]=1.4 to 11.4; number needed to treat [NNT]=6.1 (95% Cl=4 to 21). The proportion achieving the physical activity target did not increase significantly (38% versus 28% for controls; OR=1.6; 95% Cl=0.7 to 3.8).
  
  
  CONCLUSIONS
  Short-term weight loss, at a level which, if sustained, is clinically meaningful for reducing diabetes risk, is achievable in primary care, without excessive use of NHS monetary or personnel resources.
authors.affiliation: Peninsula Medical School, Exeter. Colin.Greaves@pms.ac.uk
authors.forename: Colin J
authors.initials: CJ
authors.lastname: Greaves
authors.forename: Andrew
authors.initials: A
authors.lastname: Middlebrooke
authors.forename: Lucy
authors.initials: L
authors.lastname: O'Loughlin
authors.forename: Sandra
authors.initials: S
authors.lastname: Holland
authors.forename: Jane
authors.initials: J
authors.lastname: Piper
authors.forename: Anna
authors.initials: A
authors.lastname: Steele
authors.forename: Tracy
authors.initials: T
authors.lastname: Gale
authors.forename: Fenella
authors.initials: F
authors.lastname: Hammerton
authors.forename: Mark
authors.initials: M
authors.lastname: Daly
mesh_terms: D001294:Attitude to Health; D003376:Counseling; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D015444:Exercise; D005260:Female; D006293:Health Promotion / Q000379:methods; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009042:Motivation; D010353:Patient Education as Topic / Q000379:methods; D012307:Risk Factors; D016037:Single-Blind Method; D016896:Treatment Outcome; D015431:Weight Loss