Rhodium-catalyzed enantio- and diastereoselective intramolecular [2 + 2 + 2] cycloaddition of unsymmetrical dienynes.
A cationic rhodium(i)/(R)-H(8)-BINAP or (R)-Segphos complex catalyzes an intramolecular [2 + 2 + 2] cycloaddition of unsymmetrical dienynes, leading to fused tri- and tetracyclic cyclohexenes bearing two tertiary or quaternary carbon centers in high yields with high enantio- and diastereoselectivity.
Sagae
Hiromi
H
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan.
Noguchi
Keiichi
K
Hirano
Masao
M
Tanaka
Ken
K