title: Infiltration of histiocytes and multinucleated giant cells in the myocardium of a patient with multicentric reticulohistiocytosis.
abstract: Multicentric reticulohistiocytosis (MRH) is a rare multisystem disease characterized by skin nodules and a destructive polyarthritis. We describe cardiac disease in a 42-year-old African American female with a history of MRH for 29 years and dilated cardiomyopathy for 5 years. During a congestive heart failure flare, the patient was slow to respond to standard treatment. A left/right heart catheterization and endomyocardial biopsy were performed, and the patient was found to have evidence of myocardial MRH infiltration.
authors.affiliation: Division of Rheumatology, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
authors.forename: Tamika
authors.initials: T
authors.lastname: Webb-Detiege
authors.forename: Harvey
authors.initials: H
authors.lastname: Sasken
authors.forename: Primal
authors.initials: P
authors.lastname: Kaur
mesh_terms: D000328:Adult; D001741:Black or African American; D001168:Arthritis / Q000150:complications; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D005260:Female; D006644:Histiocytes / Q000473:pathology*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000150:complications* / Q000473:pathology*; D006801:Humans; D009206:Myocardium / Q000473:pathology*