Dyspnea in interstitial lung disease.
OBJECTIVE
Dyspnea is a common complication of interstitial lung disease, yet little is known about its cause and effective management. This review attempts to summarize the current state of the art in this area.


RESULTS
Dyspnea is a near-universal finding in people with interstitial lung disease, predominantly due to neuromechanical abnormalities. Several well studied metrics exist for the measurement of dyspnea in this population, and its severity has been linked to quality of life and survival. The management of dyspnea in interstitial lung disease remains a challenge, with no proven pharmacological options. Pulmonary rehabilitation shows therapeutic promise, and aggressive treatment of physical and psychiatric comorbidities is important.


CONCLUSIONS
Dyspnea remains a common and difficult to treat symptom for people with interstitial lung disease. More research is sorely needed.
Collard
Harold R
HR
Department of Medicine, University of California San Francisco, San Francisco, California 94143, USA. hal.collard@ucsf.edu
Pantilat
Steven Z
SZ
D004417:Dyspnea / Q000175:diagnosis / Q000209:etiology* / Q000534:rehabilitation; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010102:Oxygen Inhalation Therapy; D011379:Prognosis; D012720:Severity of Illness Index