[The influence of damage factors of the different nature on the lipid composition in the mice liver].
The combined effect of the X-rays at the dose of 4 and 5 Gy and the Tween 80 (the 0.3% solution) in the 10% solution of the water acetone on the lipid composition in the mice Balb/c liver is studied after 1 month. It is revealed that the disturbance of the linear dependence of "biological effect-dose" is due to the enhancement of the action of the acute X-rays with sublethal doses after the preliminary administration of the low toxic chemical agents at low doses on the lipid composition of the mice liver. The decrease of differences in the scale of the correlation between the generalized phospholipid composition parameters in the mice liver after combined action of the chemical and physical factors is shown. The interrelation between the mice Balb/c survival and the ratio of the general phospholipid fractions of the lipid liver in the age control groups is found.
Kozlov
M V
MV
Shishkina
L N
LN
D000096:Acetone / Q000633:toxicity*; D000818:Animals; D041702:BALB 3T3 Cells; D004307:Dose-Response Relationship, Radiation; D008099:Liver / Q000737:chemistry / Q000187:drug effects* / Q000528:radiation effects*; D008297:Male; D051379:Mice; D010743:Phospholipids / Q000032:analysis*; D011136:Polysorbates / Q000633:toxicity*; D012996:Solutions; D013501:Surface-Active Agents / Q000633:toxicity*; D013997:Time Factors; D014965:X-Rays
D010743:Phospholipids; D011136:Polysorbates; D012996:Solutions; D013501:Surface-Active Agents; D000096:Acetone