title: Concurrent B-cell chronic lymphocytic leukemia and multiple myeloma treated successfully with lenalidomide.
abstract: The occurrence of multiple myeloma and chronic lymphocytic leukemia in the same patient is very uncommon. The immunomodulatory agent lenalidomide has been shown to have high response rates in multiple myeloma and appears to be quite active in advanced CLL. We report two patients with concurrent CLL and MM who were both treated successfully with lenalidomide.
authors.affiliation: Division of Hematology/Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, HWCRB-4th Floor, 4100 John R, Detroit, MI 48201, USA. srinivas@karmanos.org
authors.forename: Sridhar
authors.initials: S
authors.lastname: Srinivasan
authors.forename: Charles A
authors.initials: CA
authors.lastname: Schiffer
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D000077269:Lenalidomide; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy* / Q000503:physiopathology; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy* / Q000503:physiopathology; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D013792:Thalidomide; D000077269:Lenalidomide