title: Undifferentiated carcinoma of the esophagus with rapid growth of lymph node. A case report and review of the literature.
abstract: We present a case of undifferentiated carcinoma of the esophagus (UCE) treated with chemotherapy consisting of 5-fluorouracil plus nedaplatin and radiotherapy. The patient developed rapid growth of lymph nodes and died of massive hematemesis 2 months after the diagnosis. UCE is rare but highly malignant. Since there is no established treatment for UCE, its clinical outcome is invariably poor. We also reviewed the effectiveness of chemotherapy against UCE.
authors.affiliation: Second Department of Surgery, Dokkyo University School of Medicine, Tochigi, Japan. smori4281@mac.com
authors.forename: Shozo
authors.initials: S
authors.lastname: Mori
authors.forename: Nobumi
authors.initials: N
authors.lastname: Tagaya
authors.forename: Kiyoshige
authors.initials: K
authors.lastname: Hamada
authors.forename: Aya
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Tokihiko
authors.initials: T
authors.lastname: Sawada
authors.forename: Koichi
authors.initials: K
authors.lastname: Honma
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kubota
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D017024:Chemotherapy, Adjuvant; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D004945:Esophagoscopy; D017809:Fatal Outcome; D005472:Fluorouracil / Q000008:administration & dosage; D006396:Hematemesis / Q000209:etiology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D018714:Radiotherapy, Adjuvant
chemical_list: D009944:Organoplatinum Compounds; C053989:nedaplatin; D005472:Fluorouracil