Impaired spermatogenesis by testicular sarcoidosis.
Testicular involvement by sarcoidosis is a rare condition. A 23-year-old Japanese man had asymptomatic bilateral testicular lesions, which were detected by gallium scintigram, together with lesions located bilaterally in the uvea, lungs and hilar, and mediastinal lymph nodes and unilateral supraclavicular lymph nodes. Semen analysis demonstrated severely impaired spermatogenesis. Treatment with corticosteroid dramatically improved these lesions and restored spermatogenesis. This case report suggests that testicular sarcoidosis may cause male infertility.
Takiguchi
Yuichi
Y
Department of Respirology B2, Graduate School of Medicine, Chiba University, Chiba, Japan. takiguchi@faculty.chiba-u.jp
Matsuno
Daisuke
D
Kurosu
Katsushi
K
Okada
Osamu
O
Tatsumi
Koichiro
K
Ohta
Sho
S
Ichikawa
Tomohiko
T
Kuriyama
Takayuki
T
D000284:Administration, Oral; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012507:Sarcoidosis / Q000188:drug therapy / Q000473:pathology*; D055101:Semen Analysis; D013091:Spermatogenesis / Q000187:drug effects / Q000502:physiology*; D013094:Spermatozoa / Q000473:pathology*; D013733:Testicular Diseases / Q000188:drug therapy / Q000473:pathology*; D055815:Young Adult
D005938:Glucocorticoids; D011239:Prednisolone