title: [PSA variations in persons with latent prostate cancer].
abstract: The introduction and common use of serum PSA (Prostate Specific Antigen) has been demonstrated a useful index on latent prostate cancer diagnostic but in the same time has increased surgical intervention on histological forms with no eventual future evolution. Benign comportment of latent carcinomas being well known in advance, we correlated in vitro serum PSA from latent tumors, with the samples from a control group (prostates without signs of malignization). Levels of PSA were slightly elevated compared to age norms, mainly in cases with a large coexistent hypertrophy. Our reduced sample does not stand any statistic analysis, but this observation could eventually explain increased diagnostic and hyper-treatment of non-important carcinomas from a clinical point of view.
authors.affiliation: General Hospital of Thebes, University of Medicine and Pharmacy Gr.T. Popa Iaşi, School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Stamatiou
authors.forename: M
authors.initials: M
authors.lastname: Danciu
authors.forename: C
authors.initials: C
authors.lastname: Karakos
authors.forename: F
authors.initials: F
authors.lastname: Sofras
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D002277:Carcinoma / Q000175:diagnosis* / Q000276:immunology*; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000276:immunology*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen