title: Brain abscess caused by Cladophialophora Bantiana in an immunocompetent host: need for a novel cost-effective antifungal agent.
abstract: We report a 53-year-old male who presented with headache, tremor and memory disturbance. Radiological evaluation was suggestive of brain abscess. He underwent gross total excision of the cerebral abscess. The histopathological examination and pus culture was suggestive of brain abscess caused by Cladophialophora bantiana. Authors report a rare case of biopsy and culture proven Cladophialophora bantiana brain abscess in an immunocompetent host. The authors review the relevant literature and current treatment options while emphasizing the need for a cost-effective novel antifungal drug to salvage a subset of patients suffering from this rare but increasingly frequent condition.
authors.affiliation: Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi-110 029, India. sachin.aiims@gmail.com
authors.forename: S A
authors.initials: SA
authors.lastname: Borkar
authors.forename: M S
authors.initials: MS
authors.lastname: Sharma
authors.forename: G
authors.initials: G
authors.lastname: Rajpal
authors.forename: M
authors.initials: M
authors.lastname: Jain
authors.forename: I
authors.initials: I
authors.lastname: Xess
authors.forename: B S
authors.initials: BS
authors.lastname: Sharma
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D001922:Brain Abscess / Q000382:microbiology* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology / Q000601:surgery
chemical_list: D000935:Antifungal Agents