title: [Late-onset vaccination-induced subcutaneous pseudolymphoma].
abstract: Persistent subcutaneous nodules arise on rare occasions at sites of injection of aluminium hydroxide-adsorbed vaccine. We report a case following a diphtheria, tetanus and pertussis vaccination. The late onset of the lesion, four years after the injection, led to an uncertain preoperative diagnosis. Histopathologic examination showed features of a subcutaneous pseudolymphoma. The demonstration of aluminium by Morin staining and atomic absorption spectrometry on a paraffin-embedded tissue probe supported the diagnosis of a vaccination-induced pseudolymphoma.
authors.affiliation: Département de pathologie, CHU de Strasbourg, hôpital de Hautepierre, 1, avenue Molière, 67098 Strasbourg cedex, France.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Croce
authors.forename: Benoît
authors.initials: B
authors.lastname: Lhermitte
authors.forename: Catherine
authors.initials: C
authors.lastname: Tomasetto
authors.forename: Olivier
authors.initials: O
authors.lastname: Guillard
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Bellocq
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Chenard
mesh_terms: D000535:Aluminum; D004396:Coloring Agents; D003937:Diagnosis, Differential; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D019310:Pseudolymphoma / Q000139:chemically induced* / Q000473:pathology*; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology
chemical_list: D004396:Coloring Agents; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D000535:Aluminum