Does Helicobacter pylori play a role in the development of chronic adenotonsillitis?
OBJECTIVE
Evaluation of the possible relationship between chronic adenotonsillitis and Helicobacter pylori (HP).


METHODS
The study was performed prospectively on 91 pediatric patients who underwent tonsillectomy, adenoidectomy or adenotonsillectomy due to chronic tonsillitis and/or adenoiditis. The adenotonsillectomy specimens were examined for HP colonization by rapid urease test (RUT) and immunohistochemical evaluation. Before surgery, anti-HP IgG and IgA antibody titers were detected by enzyme linked immunosorbent assay (ELISA) test in venous blood samples of the patients.


RESULTS
The RUT was positive in only two of the adenoidectomy specimens (2.2%) and in none of the tonsillectomy specimens. A positive result was not detected in any tonsillectomy specimens using immunohistochemical examination. Serum IgG antibody was positive in 21 (23%) patients, IgA antibody was detected in 7 (7.69%) patients and both tests were positive only in 3 (3.29%) patients.


CONCLUSIONS
The results of this study suggested that HP would not colonize in tonsil tissue of patients with chronic tonsillitis.
Vayisoglu
Yusuf
Y
Mersin University, School of Medicine, Department of Otorhinolaryngology, Mersin, Turkey. yvayisoglu@gmail.com
Ozcan
Cengiz
C
Polat
Ayse
A
Delialioglu
Nuran
N
Gorur
Kemal
K
D000234:Adenoids / Q000382:microbiology*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis / Q000378:metabolism / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D011446:Prospective Studies; D014069:Tonsillitis / Q000382:microbiology*; D014510:Urease / Q000378:metabolism
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014510:Urease