title: Mechanistically inspired catalysts for enantioselective desymmetrizations by olefin metathesis.
abstract: In asymmetric olefin metathesis reactions, the addition of halide additives is often required to augment enantioselectivities, despite the fact that the additives result in catalysts with diminished reactivities. The preparation of new chiral Ru-based catalysts was accomplished by exploiting previously reported mechanistic studies. The catalysts possess a high level of reactivity and successfully induce high levels of asymmetry in desymmetrization reactions without the use of halide additives.
authors.affiliation: Department of Chemistry, Université de Montréal, Station Downtown, Montréal, PQ, Canada.
authors.forename: Pierre-André
authors.initials: PA
authors.lastname: Fournier
authors.forename: Jolaine
authors.initials: J
authors.lastname: Savoie
authors.forename: Brice
authors.initials: B
authors.lastname: Stenne
authors.forename: Marion
authors.initials: M
authors.lastname: Bédard
authors.forename: Alain
authors.initials: A
authors.lastname: Grandbois
authors.forename: Shawn K
authors.initials: SK
authors.lastname: Collins
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D013237:Stereoisomerism
chemical_list: D000475:Alkenes