title: Paraneoplastic pemphigus regression after thymoma resection.
abstract: BACKGROUND
  Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases.
  
  
  METHODS
  A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved pemphigus regression. The clinical correlations between pemphigus and thymoma are presented.
  
  
  CONCLUSIONS
  Our case report provides further evidence for the important role of autoantibodies in the pathogenesis of paraneoplastic skin diseases in thymoma patients. It also documents the improvement of the associated pemphigus after radical treatment of the thymoma.
authors.affiliation: Thoracic Surgery Department, Theagenio Cancer Hospital, Thessaloniki, Greece. nibarbet@yahoo.gr
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Barbetakis
authors.forename: Georgios
authors.initials: G
authors.lastname: Samanidis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Paliouras
authors.forename: Ioannis
authors.initials: I
authors.lastname: Boukovinas
authors.forename: Christos
authors.initials: C
authors.lastname: Asteriou
authors.forename: Eleni
authors.initials: E
authors.lastname: Stergiou
authors.forename: Kostas
authors.initials: K
authors.lastname: Laschos
authors.forename: Christodoulos
authors.initials: C
authors.lastname: Tsilikas
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000503:physiopathology*; D010392:Pemphigus / Q000503:physiopathology*; D013945:Thymoma / Q000473:pathology / Q000601:surgery*; D013953:Thymus Neoplasms / Q000473:pathology / Q000601:surgery*