title: Study on analgesic effect of traditional Chinese medicine.
abstract: Chinese medicine has been used in treating pain for a long time. Much progress has been made in studies on the mechanism of the analgesic effect of Chinese medicine in animal experiments. It is found that the analgesic action may be related to the following actions: (1) Reducing the secretion of peripheral algogenic substances and inducing the secretion of pain-sensitive substances; (2) Alleviating the accumulation of local algogenic substances; (3) Increasing the release of endogenous analgesic substances; (4) Regulating c-fos gene and increasing the secretion of such substances in the central nervous system, etc. In this paper, the experimental methods and analgesic effect of Chinese medicines are reviewed.
authors.affiliation: Department of Chinese Medicine, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Shan
authors.initials: S
authors.lastname: Yu
authors.forename: Ling
authors.initials: L
authors.lastname: Xu
authors.forename: Pin-kang
authors.initials: PK
authors.lastname: Wei
authors.forename: Zhi-feng
authors.initials: ZF
authors.lastname: Qin
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Hai-dong
authors.initials: HD
authors.lastname: Peng
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D008516:Medicine, Chinese Traditional; D023421:Models, Animal
chemical_list: D000700:Analgesics; D004365:Drugs, Chinese Herbal