Transformation of N-phenylpiperazine by mixed cultures from a municipal wastewater treatment plant.
Samples from a wastewater treatment plant were used as inocula for mixed cultures dosed with N-phenylpiperazine (NPP), a model compound containing the piperazine ring found in many fluoroquinolones. Chemical analyses showed that NPP (50 mg liter(-1)) disappeared in 12 days, with the appearance of a transient metabolite and two nitrosated compounds.
Jung
Carina M
CM
Divisions of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA.
Heinze
Thomas M
TM
Deck
Joanna
J
Strakosha
Ruth
R
Sutherland
John B
JB
D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010879:Piperazines / Q000378:metabolism*; D013997:Time Factors; D014871:Water Microbiology
D010879:Piperazines; C031503:phenylpiperazine