title: Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis Study (KIDS).
abstract: Atopic dermatitis (AD) is a multifactorial disease that usually decreases the quality of life of affected patients. The purpose of this study was to evaluate the associated factors for atopic dermatitis, asthma, rhinitis, and food allergy by physical examination of the skin and a questionnaire in nursery school children in Ishigaki Island, Okinawa, Japan. Enrolled in this study were 460 children from 0 to 6 years of age. Physical examination of skin symptoms and blood tests were performed. Information on past history and family history of atopic dermatitis, asthma, rhinitis, and food allergy were collected by questionnaire. The prevalence of atopic dermatitis was 12.2% (56/460). The cumulative prevalence of asthma, rhinitis, and food allergy was 19.9% (91/458), 3.3% (15/457), and 5.5% (25/456), respectively. In multivariate analysis, maternal history of rhinitis, atopic dermatitis siblings, past history of asthma and food allergy, and elevation of total IgE were significantly related to atopic dermatitis. A high total IgE level was a strong risk factor specific for atopic dermatitis in this population.
authors.affiliation: Department of Dermatology, Kyushu University Hospital, Maidashi 3-1-1, Higashiku, Fukuoka, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Fukiwake
authors.forename: Norihiro
authors.initials: N
authors.lastname: Furusyo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Takeoka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Toyoda
authors.forename: Norihiko
authors.initials: N
authors.lastname: Kubo
authors.forename: Makiko
authors.initials: M
authors.lastname: Kido
authors.forename: Sayaka
authors.initials: S
authors.lastname: Hayashida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Uchi
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Moroi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Urabe
authors.forename: Naoko
authors.initials: N
authors.lastname: Kinukawa
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nose
authors.forename: Jun
authors.initials: J
authors.lastname: Hayashi
authors.forename: Masutaka
authors.initials: M
authors.lastname: Furue
mesh_terms: D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007223:Infant; D007564:Japan; D012307:Risk Factors