title: Transformation of N-phenylpiperazine by mixed cultures from a municipal wastewater treatment plant.
abstract: Samples from a wastewater treatment plant were used as inocula for mixed cultures dosed with N-phenylpiperazine (NPP), a model compound containing the piperazine ring found in many fluoroquinolones. Chemical analyses showed that NPP (50 mg liter(-1)) disappeared in 12 days, with the appearance of a transient metabolite and two nitrosated compounds.
authors.affiliation: Divisions of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA.
authors.forename: Carina M
authors.initials: CM
authors.lastname: Jung
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Heinze
authors.forename: Joanna
authors.initials: J
authors.lastname: Deck
authors.forename: Ruth
authors.initials: R
authors.lastname: Strakosha
authors.forename: John B
authors.initials: JB
authors.lastname: Sutherland
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010879:Piperazines / Q000378:metabolism*; D013997:Time Factors; D014871:Water Microbiology
chemical_list: D010879:Piperazines; C031503:phenylpiperazine