Imaging in osteoarthritis.
Conventional radiography is still the first and most important imaging examination in a clinical setting when evaluating a patient with a known or suspected diagnosis of osteoarthritis (OA). In research and clinical trials, it still is a valuable tool for stratifying patients who have OA into different categories for inclusion criteria and eligibility. MRI has become crucial in understanding the natural history of the disease and in guiding future therapies because of its ability to image the knee as a whole organ and to assess cartilage morphology and composition directly and in a three-dimensional manner. The other modalities discussed in this article are valuable additional techniques indicated on a case-by-case basis.
Guermazi
Ali
A
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, Third Floor, Boston, MA 02118, USA. guermazi@bu.edu
Burstein
Deborah
D
Conaghan
Philip
P
Eckstein
Felix
F
Hellio Le Graverand-Gastineau
Marie-Pierre
MP
Keen
Helen
H
Roemer
Frank W
FW
D001027:Aortography / Q000379:methods; D003287:Contrast Media / Q000494:pharmacology; D003952:Diagnostic Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D015207:Osteoarthritis, Hip / Q000175:diagnosis*; D020370:Osteoarthritis, Knee / Q000175:diagnosis*; D011877:Radionuclide Imaging / Q000379:methods; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color / Q000379:methods
D003287:Contrast Media