The sebocyte culture: a model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acne.
Acne is the most common skin disease which affects millions of people worldwide. Seborrhea and sebostasis are major cosmetic problems but also lead occasionally to diseases. This article summarizes the data of newest research of sebostasis, seborrhoea and acne made possible through the development of human and animal sebocyte culture models.
Zouboulis
Christos C
CC
Department of Dermatology, Dessau Medical Center, Dessau, Germany. christos.zouboulis@klinikum-dessau.de
Schagen
Silke
S
Alestas
Theodosios
T
D000152:Acne Vulgaris / Q000503:physiopathology*; D002478:Cells, Cultured; D003346:Corticotropin-Releasing Hormone / Q000502:physiology; D012628:Dermatitis, Seborrheic / Q000503:physiopathology*; D005227:Fatty Acids / Q000096:biosynthesis; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology; D050155:Lipogenesis; D008297:Male; D047492:Peroxisome Proliferator-Activated Receptors / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D012627:Sebaceous Glands / Q000166:cytology* / Q000187:drug effects / Q000503:physiopathology*; D012629:Sebum / Q000502:physiology*
D005227:Fatty Acids; D047492:Peroxisome Proliferator-Activated Receptors; D011956:Receptors, Cell Surface; D003346:Corticotropin-Releasing Hormone