Clinical observation on treatment of post-craniocerebral traumatic mental disorder by integrative medicine.
OBJECTIVE
To observe the clinical efficacy of integrative medical therapy in treating post-craniocerebral traumatic mental disorder (PCT-MD).


METHODS
Sixty patients with confirmed diagnosis of PCT-MD were randomly assigned to the treated group and the control group equally. All were treated by conventional comprehensive Western medicine, but to patients in the treated group, modified Xufu Zhuyu Decoction (XFZY) was additionally given and the therapeutic course for both groups was 20 days. Changes in mental symptoms were observed and recorded on the 10th and 20th day and clinical efficacy as well as cranial CT image was estimated after termination of the treatment.


RESULTS
The clinical effective rate in the treated group and the control group was 96.67% and 83.30% respectively. Comparison between them showed significant difference (P<0.05). Significant differences were also shown in the comparisons between the two groups in improving mental symptoms, either on the 10th or on the 20th day (P<0.05 and P<0.01 respectively), and in post-treatment cranial CT image (P<0.05).


CONCLUSIONS
Better efficacy could be obtained by integrative medical therapy in treating PCT-MD.
Sun
Mei
M
Department of Traditional Chinese Medicine, the Second Hospital Affiliated to Medical College of Zhejiang University, Hangzhou, China. kathetyluogaz@tom.com
Zhan
Xiao-ping
XP
Jin
Chen-yu
CY
Shan
Jian-zhen
JZ
Xu
Shu
S
Wang
Yun-lai
YL
D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000009:adverse effects; D001523:Mental Disorders / Q000188:drug therapy*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal