[Surgical site infection following proximal GIT procedures].
BACKGROUND
Surgical site infections (ICHM) remain a serious problem in the proximal GIT surgery, with incidence rates from 5% to 26% in planned procedures, and up to 40% in urgent procedures. Surgical site infections result in increased postooperative morbidity and mortality rates, prolonged hospitalization and increased treatment costs. Minimalization of the surgical site infection rates is an important epidemiological and therapeutical objective.


OBJECTIVE
A retrospective study assessed surgical site infections rates in urgent and elective procedures on the proximal GIT, and in a selected group of elective procedures on the large intestine and rectum. The significance of some risk factors was assessed based on analyses of surgical site infections in all subjects operated during the two-year study period.


METHODS
Infection rates following urgent procedures were analysed in 545 subjects operated for acute abdomen during 2003-2004. In another study group of 4667 subjects operated during 2005-2006, surgical site infection rates were analysed based on assessment of some risk factors. In this group, incidence of surgical site infections in 640 patients following proximal GIT procedures was studied. In a selected group of 192 elective colorectal procedures, incidence rates of surgical site infections and peritoneal infections were evaluated.


RESULTS
Surgical site infections occurred in 71 (13 %) of the subjects in the group of 545 patients operated for acute abdomen. In 48 patients, the microbiological findings in surgical site infections were positive with the following commonest pathogens: Escherichia coli, staphylococci and Enteroccocus faecalis. Surgical site infections were demonstrated in 217 subjects (4.6%) out of the total of 4667 patients included in the study group. The surgical site infections risk factors, which were found statistically significant (p < 0.05), included the procedure's duration over 2 hours (p = 0.042) and the age > 50 (p = 0.047). Surgical site infections occurred most frequently in the group of 640 subjects with proximal GIT procedures, classified as septic procedures (surgical site infections in 28.5% and in the peritenal cavity in 8%). In the group of 192 subjects with colorectal procedures, the surgical site infections occurred in 6.8%, peritoneal cavity infections in 3.1% of the subjects.


CONCLUSIONS
Surgical site infections are the commonest postoperative infections in proximal GIT surgeries. The surgical site is the commonest location. The principal pathogens following urgent procedures include Enterobacteriacae, enterococci and staphylococci. The following risk factors were found statistically significant: the procedure's duration (> 2 hours) and the patient's age (< 50 years).
Vyhnánek
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Chirurgicklá klinika 3. LF UK a FNKV Praha. vyhnanek@fnkv.cz
Duchác
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Skála
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Teplan
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D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000382:microbiology