[RuII(NO+)]3+-core complexes with 4-methyl-pyrimidine and ethyl-isonicotinate: synthesis, X-ray structure, spectroscopy, and computational and NO-release studies upon UVA irradiation.
The reaction of RuCl(3)(NO).H(2)O with 4-methylpyrimidine (MePYM) and ethylisonicotinate (EINT), in absolute ethanol at 40-55 degrees C afforded crystalline trans-[RuCl(3)(NO)L(2)] complexes. Structural studies via X-ray diffraction, and spectroscopic methods (NMR, IR, UV-visible (UV-Vis)) revealed that the molecular structures have the two Ls in trans positions (axial) and the chloride anions and the NO(+) cation as equatorial ligands; pyrimidine...pyrimidine pairing pattern via two weak C-H...N interactions occur. The molecular structures for the EINT derivative was inferred from spectroscopy and computations. Under irradiation at 366 nm several solutions of the title compounds deliver NO via first order processes. Visible light (420-700 nm) does not produce significant NO release from CH(2)Cl(2) and CH(3)CN solutions within 24h.
Tamasi
Gabriella
G
Department of Chemical and Biosystem Sciences and Technologies, University of Siena, Via A. Moro 2, I-53100 Siena, Italy.
Curci
Matia
M
Berrettini
Francesco
F
Justice
Nicholas
N
Sega
Alessandro
A
Chiasserini
Luisa
L
Cini
Renzo
R
D018360:Crystallography, X-Ray; D007539:Isonicotinic Acids / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*; D017975:Ruthenium Compounds / Q000737:chemistry*; D013057:Spectrum Analysis; D014466:Ultraviolet Rays; D014961:X-Ray Diffraction
D007539:Isonicotinic Acids; D008024:Ligands; D009942:Organometallic Compounds; D011743:Pyrimidines; D017975:Ruthenium Compounds; C094021:ethyl isonicotinate; C030986:pyrimidine