title: Obesity and persisting sleep apnea after adenotonsillectomy in Greek children.
abstract: BACKGROUND
  The relative importance of obesity and adenotonsillar hypertrophy in the pathogenesis of obstructive sleep-disordered breathing (SDB) in childhood is unclear. Adenotonsillectomy (AT) for SDB is not always curative, and obese children are at increased risk for residual disease postoperatively.
  
  
  OBJECTIVE
  The aim of this investigation was to assess the efficacy of AT as treatment for SDB in obese and nonobese children.
  
  
  METHODS
  Children with adenoidal and/or tonsillar hypertrophy who underwent AT for the treatment of SDB underwent polysomnography preoperatively and postoperatively. A body mass index (BMI) z score of > 1.645 was used to define obesity. The achievement of a postoperative obstructive apnea-hypopnea index (OAHI) of less than one episode per hour (ie, the cure of SDB) was the primary outcome measure.
  
  
  RESULTS
  Twenty-two obese children (mean [+/- SD] age, 5.8 +/- 1.8 years; mean BMI z score, 2.6 +/- 0.8; mean OAHI, 9.5 +/- 9.7 episodes per hour) and 48 nonobese children (mean age, 6.9 +/- 2.6 years; mean BMI z score, 0.09 +/- 1.1; OAHI, 6 +/- 5.4 episodes per hour) were recruited. After surgery, obese and nonobese subjects did not differ in the efficacy of AT (postoperative OAHI of less than one episode per hour, 22.7% vs 25% of subjects, respectively; p > 0.05). The presence of obesity, adenoidal or tonsillar hypertrophy, gender, and postoperative BMI change were not significant predictors of SDB cure.
  
  
  CONCLUSIONS
  Obesity does not necessarily predict an unfavorable outcome of AT as treatment for SDB.
authors.affiliation: Department of Otorhinolaryngology, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Maria T
authors.initials: MT
authors.lastname: Apostolidou
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Emmanouel I
authors.initials: EI
authors.lastname: Alexopoulos
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Chaidas
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Georgia
authors.initials: G
authors.lastname: Ntamagka
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Karathanasi
authors.affiliation: Department of Otorhinolaryngology, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Theoharis I
authors.initials: TI
authors.lastname: Apostolidis
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Gourgoulianis
authors.affiliation: Sleep Disorders Laboratory, University of Thessaly School of Medicine, Larissa, Greece. Electronic address: KADITIA@hotmail.com.
authors.forename: Athanasios G
authors.initials: AG
authors.lastname: Kaditis
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology*; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D006115:Greece; D006801:Humans; D006984:Hypertrophy / Q000150:complications / Q000473:pathology / Q000601:surgery; D008297:Male; D009765:Obesity / Q000150:complications* / Q000473:pathology / Q000601:surgery; D014066:Palatine Tonsil / Q000473:pathology*; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000473:pathology / Q000601:surgery*; D014068:Tonsillectomy; D016896:Treatment Outcome