Electrocardiographic features in a patient with the coexistence of long QT syndrome and coronary vasospasm.
A 20-year-old woman suffered from cardiopulmonary arrest due to ventricular fibrillation. The electrocardiogram after resuscitation showed prolonged QTc interval with bifid T wave. On the third hospital day, the QTc interval and the T-wave changes improved. However, the QTc interval was distinctively prolonged after administration of epinephrine, oral glucose load, and intracoronary acetylcholine (Ach) into the left coronary artery. Moreover, an injection of Ach into the right coronary artery provoked severe coronary spasm. This is a case of the coexistence of long QT syndrome (LQTS) and coronary vasospasm, which may give an important clinical implication for the treatment of LQTS.
Tanaka
Yasuaki
Y
Department of Cardiology, Yokohama Minami Kyosai Hospital, Kanagawa, Yokohama, Japan. yasuaki@mxk.mesh.ne.jp
Nishizaki
Mitsuhiro
M
Yamawake
Noriyoshi
N
Sakurada
Harumizu
H
Hiraoka
Masayasu
M
D000109:Acetylcholine; D000293:Adolescent; D003329:Coronary Vasospasm / Q000150:complications* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000187:drug effects* / Q000379:methods*; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000150:complications* / Q000175:diagnosis*
D000109:Acetylcholine