title: [Autologous bone marrow integrating artificial bone and ilium periosteum transplantation for treatment of bone nonunion].
abstract: OBJECTIVE
  To evaluate the initial clinical effect of the autologous bone marrow integrating artificial bone and ilium periosteum transplantation in treatment of problematic nonunion.
  
  
  METHODS
  From January 2004 to July 2006, 12 patients (13 limbs)with problematic nonunion were treated with autologous bone marrow integrating artificial bone and ilium periosteum. There were 8 males and 4 females, aged 17-58 years old. The position of nonunion were the tibia in 7 limbs, the femur in 3 limbs, the humerus in 2 limbs. The operated number was 1-4, mean 2.5. The time from injury to therapy was 13 months to 9 years, mean 47.6 months. The bone defect distance was 6-30 mm (mean 15 mm) through 1 : 1 X-rays before operation. Eleven limbs were treated by internal fixation (10 limbs by the bone nail and 1 limb by the limited contact-dynamic compression plate), 2 limbs were treated by the external fixation. The X-ray films were taken at 1 day, 1, 3, 6, 9, 12 months after operation to observe fracture union.
  
  
  RESULTS
  All patients were followed up for 12-26 months (mean 17.5 months) and achieved union within 4-7 months (mean 6 months). No deformity of rotation, angulation and crispation occurred in 13 limbs, but functional impairment occurred in 6 limbs after union of fracture.
  
  
  CONCLUSIONS
  Autologous bone marrow integrating artificial bone and ilium periosteum transplantation for treatment of problematic nonunion has the satisfactory result.
authors.affiliation: Department of Orthopedics, Affiliated Hospital of Luzhou Medical College, Luzhou Sichuan, 646000, PR China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Ge
authors.forename: Yukai
authors.initials: Y
authors.lastname: Lei
authors.forename: Ruisheng
authors.initials: R
authors.lastname: Xu
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Lu
authors.forename: Dechou
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D018786:Bone Substitutes; D005260:Female; D005500:Follow-Up Studies; D005599:Fractures, Ununited / Q000601:surgery*; D006801:Humans; D007085:Ilium; D008297:Male; D008875:Middle Aged; D010521:Periosteum / Q000637:transplantation*
chemical_list: D018786:Bone Substitutes