title: Carcinogenic effect of an antitumor drug etoposide in laboratory animals.
abstract: Intravenous injection of antitumor drug etoposide in the maximum tolerated dose was followed by the development of breast cancer in 38.1% female Wistar rats and 6.7% female outbred mice.
authors.affiliation: Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences. toxicology_lab@mail.ru
authors.forename: T I
authors.initials: TI
authors.lastname: Fomina
authors.forename: V M
authors.initials: VM
authors.lastname: Perelmuter
authors.forename: S V
authors.initials: SV
authors.lastname: Vtorushin
authors.forename: M V
authors.initials: MV
authors.lastname: Zavjalova
authors.forename: T G
authors.initials: TG
authors.lastname: Borovskaja
authors.forename: E A
authors.initials: EA
authors.lastname: Timina
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000633:toxicity*; D001943:Breast Neoplasms / Q000139:chemically induced / Q000473:pathology*; D005047:Etoposide / Q000008:administration & dosage / Q000633:toxicity*; D005260:Female; D007275:Injections, Intravenous; D051379:Mice; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000970:Antineoplastic Agents; D005047:Etoposide