title: Vasospasm and stroke attributable to ephedra-free xenadrine: case report.
abstract: Following the 2004 ban of ephedra, which was linked to several cases of stroke and myocardial infarction, manufacturers have marketed "ephedra-free" weight loss products that include the active ingredient synephrine. Despite the lack of data on safety and efficacy, synephrine is touted by its promoters as a "safe" alternative to ephedra and is often combined with caffeine, as in the supplement Xenadrine-EFX. We report a case of left middle cerebral artery vasopasm and stroke in a young healthy patient in the setting of Xenadrine-EFX use.
authors.affiliation: Walter Reed Army Medical Center, Silver Spring, MD 20910, USA.
authors.forename: Robert O
authors.initials: RO
authors.lastname: Holmes
authors.forename: Jinny
authors.initials: J
authors.lastname: Tavee
mesh_terms: D000328:Adult; D019587:Dietary Supplements / Q000009:adverse effects*; D029789:Ephedra / Q000009:adverse effects*; D005260:Female; D006801:Humans; D028321:Plant Preparations / Q000009:adverse effects*; D012307:Risk Factors; D020521:Stroke / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D020301:Vasospasm, Intracranial / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology
chemical_list: D028321:Plant Preparations