title: [Cathepsin S in pathogenesis of neurological diseases].
abstract: Cathepsin S, one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. Those functions are closely associated with the pathogenesis of various neurological diseases. It would be beneficial to elucidate the role of Cathepsin S in the pathogenesis of various neurological diseases.
authors.affiliation: Department of Neurology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
authors.forename: Da-Ming
authors.initials: DM
authors.lastname: Wang
authors.forename: Jian-Ren
authors.initials: JR
authors.lastname: Liu
authors.forename: Hao-Yu
authors.initials: HY
authors.lastname: Hu
authors.forename: Guo-Ping
authors.initials: GP
authors.lastname: Shi
mesh_terms: D000544:Alzheimer Disease / Q000503:physiopathology*; D001254:Astrocytoma / Q000503:physiopathology*; D001932:Brain Neoplasms / Q000503:physiopathology*; D002403:Cathepsins / Q000502:physiology*; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000503:physiopathology*
chemical_list: D002403:Cathepsins; C028217:cathepsin S