Comparison of groupings among members of the genus Aspergillus based on phylogeny and production of bioactive compounds.
Three hundred sixty-six Aspergillus strains preserved at the National Institute of Technology and Evaluation (NITE) were compared as to phylogenetic relationships (11 species-clusters) based on the DNA sequences of the D1/D2 domains of LSU rRNA and ITS regions, including the 5.8S rRNA and biological activities of their secondary metabolites. The results showed relatively well correlation between the phylogenetic distribution and the production of bioactive compounds, especially, antimicrobial activities.
Anzai
Kozue
K
NITE Biotechnology Development Center, Department of Biotechnology, National Institute of Technology and Evaluation, Chiba, Japan.
Mayuzumi
Shinzo
S
Nakashima
Takuji
T
Sato
Hajime
H
Inaba
Shigeki
S
Park
Ju-Young
JY
Kuwahara
Natsumi
N
Suzuki
Rieko
R
Utsumi
Noriko
N
Yokoyama
Fumie
F
Ohfuku
Yuko
Y
Ando
Katsuhiko
K
D001230:Aspergillus / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D004271:DNA, Fungal / Q000235:genetics; D010802:Phylogeny
D004271:DNA, Fungal