Food allergy mediated by IgG antibodies associated with migraine in adults.
BACKGROUND
Migraine occurs with a high prevalence of 18 per cent. Management requires a tailored regimen of pharmacological and other measures based on individual clinical history. In some patients, allergen-specific IgG has been suspected to be involved in their mechanism, however, serological methods to investigate such possibility, are seldomly used.


OBJECTIVE
The aim of this study was to investigate allergen-specific IgG in serum of patients with migraine refractory to traditional treatment.


METHODS
Serum antibodies to specific 108 food allergens were measured by enzyme immunoassay from 56 patients with migraine and a control group without migraine.


RESULTS
In addition to statistical significant differences in the number of positives for IgG food allergens between patients with migraine and a controlled group, elimination diets successfully control the migraine without the need of medications.


CONCLUSIONS
According to the results obtained, serum IgG antibodies to common food should be investigated in patients with migraine.
Arroyave Hernández
Carlos M
CM
Centro de Inmunología y Alergias, Querétaro, Querétaro, México.
Echavarría Pinto
Mauro
M
Echevarría Pinto
Mauro
M
Hernández Montiel
Hebert Luis
HL
D000328:Adult; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications* / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence
D007074:Immunoglobulin G