Development of the NADPH-diaphorase-positive neurons in the sympathetic ganglia.
Changes in the distribution of NADPH-diaphorase (NADPH-d) were studied in neurons of the superior cervical ganglion (SCG), stellate ganglion (SG) and celiac ganglia (CG) in newborn, 10-, 20-day-old, 1-month-old, 2-month-old and 6-month-old rats, mice and kittens. NADPH-d-positive neurons were revealed in all sympathetic ganglia in kittens but not in rodents from birth onwards. In kittens, the largest population of NADPH-d-positive cells was found in the SG, the smallest in the SCG (<1%) and we observed only a few cells in the CG. The proportion of NADPH-d-positive cells in the SG increased from 3.1 +/- 0.15% in newborn kittens to 9.3 +/- 0.63% in 20-day-old animals and decreased further from 8.1 +/- 0.75% in 30-day-old kittens to 3.4 +/- 0.54% in 2-month-old animals. The content of NADPH-d-positive cells in the CG and SCG did not change during development. There were no differences in cross-sectional area between neurons located in different ganglia of animals from the same age group under study. We conclude that the development of NADPH-d-positive neurons in different sympathetic ganglia has its own time dynamics and is completed by the end of the second month of life.
Emanuilov
Andrey I
AI
Department of Human Anatomy, Yaroslavl State Medical Academy, Yaroslavl, Russia.
Korzina
Marina B
MB
Archakova
Liudmila I
LI
Novakovskaya
Svetlana A
SA
Nozdrachev
Alexandr D
AD
Masliukov
Petr M
PM
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D005728:Ganglia, Sympathetic / Q000201:enzymology* / Q000254:growth & development*; D006651:Histocytochemistry; D051379:Mice; D009252:NADPH Dehydrogenase / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar; D013045:Species Specificity
D009252:NADPH Dehydrogenase