title: Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting with diffusion MR imaging changes.
abstract: Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during subacute exacerbation. Vasculitic changes in biopsy studies as well as the elevation of antithyroid antibodies and CSF protein suggests an inflammatory cause. We report the case of a patient with SREAT with changes on diffusion-weighted MR imaging, which improved with corticosteroid therapy and plasmapheresis, supporting the theory of inflammatory changes in exacerbation of presumptive SREAT.
authors.affiliation: Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.
authors.forename: C
authors.initials: C
authors.lastname: Grommes
authors.forename: C
authors.initials: C
authors.lastname: Griffin
authors.forename: K A
authors.initials: KA
authors.lastname: Downes
authors.forename: A J
authors.initials: AJ
authors.lastname: Lerner
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D050031:Hashimoto Disease / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents