title: Pregnancy outcome in preimplantation genetic diagnosis cycle by blastomere biopsy is related to both quality and quantity of embryos on day 3.
abstract: The aim of this study was to determine the impact of day 3 embryo quality and quantity on subsequent embryonic development and pregnancy outcome following embryo biopsy. The findings demonstrate that a significantly lower proportion of poor/fair-quality embryos develop further after biopsy, and that patients with <4 good embryos on day 3 may have poor outcome. Therefore, appropriate counseling needs to be given to them before therapy is initiated.
authors.affiliation: Reproductive Medical Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.forename: Canquan
authors.initials: C
authors.lastname: Zhou
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Xu
authors.forename: Cong
authors.initials: C
authors.lastname: Fang
authors.forename: Minfang
authors.initials: M
authors.lastname: Zhang
mesh_terms: D000328:Adult; D001706:Biopsy; D001757:Blastomeres / Q000473:pathology*; D004624:Embryo Transfer / Q000379:methods*; D047108:Embryonic Development / Q000502:physiology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D019836:Preimplantation Diagnosis / Q000379:methods*; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies; D013997:Time Factors