title: Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform.
abstract: We demonstrate in vivo volumetric bidirectional blood flow imaging in animal models using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image half-planes, enabling volumetric bidirectional flow mapping without manual segmentation.
authors.affiliation: Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA. yt13@duke.edu
authors.forename: Yuankai K
authors.initials: YK
authors.lastname: Tao
authors.forename: Anjul M
authors.initials: AM
authors.lastname: Davis
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Izatt
mesh_terms: D000465:Algorithms; D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology*; D002642:Chick Embryo; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D051379:Mice; D012212:Rheology / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*