title: [Clinical analysis of 21 cases of cervical adenosquamous carcinoma].
abstract: OBJECTIVE
  To study the clinical characteristics, treatment modalities and prognosis of cervical adenosquamous carcinoma.
  
  
  METHODS
  The data of 21 patients with adenosquamous cervical cancer who were admitted into Zhongnan Hospital, Wuhan University from Jan 2001 to Dec 2005 were analyzed retrospectively. Six patients received surgical therapy only and 15 patients received combined therapy.
  
  
  RESULTS
  Seven cases were with positive pelvic lymph node metastases and 3 cases were with ovarian metastases. The median survival time of the combined therapy group and surgical therapy group was 54 and 20 months, respectively. In stage I and stage II patients, the median survival time of the combined therapy group and surgical therapy group was 66 and 20 months, respectively. The difference was significant between the two groups (P < 0.05).
  
  
  CONCLUSIONS
  Combined therapy should be given to patients with adenosquamous carcinoma of the cervix. Surgical therapy and chemotherapy play an important role in the management and prognosis of adenoquamous carcinoma of cervix. Preserve of ovary for patients with adenosquamous carcinoma of the cervix should only be done when the ovary is confirmed free from any malignant involvement by pathology.
authors.affiliation: Department of Gynecological Oncology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
authors.forename: Hong-Ning
authors.initials: HN
authors.lastname: Cai
authors.forename: Xu-Feng
authors.initials: XF
authors.lastname: Wu
authors.forename: Qun-Ying
authors.initials: QY
authors.lastname: Xiang
authors.forename: Yong-Yan
authors.initials: YY
authors.lastname: Xiong
authors.forename: Jun
authors.initials: J
authors.lastname: Zeng
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018196:Carcinoma, Adenosquamous / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D010052:Ovariectomy; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*
chemical_list: D002945:Cisplatin