The chemical and hydroxyl radical scavenging activity changes of ginsenoside-Rb1 by heat processing.
The chemical and hydroxyl radical (*OH) scavenging activity changes of ginsenoside Rb(1) (Rb(1)) by heat processing were investigated in this study. Rb(1) was changed into 20(S)-Rg(3), 20(R)-Rg(3), Rk(1), and Rg(5) by heat processing through glucosyl elimination and epimerization of carbon-20 by SN1 reaction. The glucosyl moiety, separated from Rb(1), made Maillard reaction product (MRPs) with glycine. The generations of 20(S)-Rg(3) and MRPs were related to the increased OH scavenging activity of Rb(1) by heat processing.
Lee
Yong Jae
YJ
Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Shillim-Dong San 56-1, Seoul 151-742, Republic of Korea.
Kim
Hyun Young
HY
Kang
Ki Sung
KS
Lee
Jin Gyun
JG
Yokozawa
Takako
T
Park
Jeong Hill
JH
D002626:Chemistry, Pharmaceutical / Q000379:methods; D002851:Chromatography, High Pressure Liquid; D004578:Electron Spin Resonance Spectroscopy; D016166:Free Radical Scavengers / Q000494:pharmacology; D036145:Ginsenosides / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry; D005998:Glycine / Q000737:chemistry; D006358:Hot Temperature; D017665:Hydroxyl Radical; D008027:Light; D015416:Maillard Reaction; D008956:Models, Chemical; D005894:Panax / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D013481:Superoxides
D016166:Free Radical Scavengers; D036145:Ginsenosides; D010936:Plant Extracts; D013481:Superoxides; D017665:Hydroxyl Radical; C442759:ginsenoside Rb1; D005947:Glucose; D005998:Glycine