title: Cutaneous pythiosis in a nontravelled California horse.
abstract: An 18-year-old Arabian mare was examined with a large mass on the left hind pastern and fetlock. The mare was located in the Central Valley of northern California, and had never been out of the state. Routine histopathological processing and examination of biopsy samples from the mass showed several hyphal organisms that were delineated with a silver stain. Using immunohistochemistry the organism was diagnosed as Pythium insidiosum. The owner declined debulking surgery, and despite treatment with an immunotherapeutic vaccine, the horse's condition deteriorated leading to euthanasia.
authors.affiliation: Department of Medicine and Epidemiology, University of California, Davis, California 95616, USA. sdwhite@ucdavis.edu
authors.forename: Stephen D
authors.initials: SD
authors.lastname: White
authors.forename: Majid
authors.initials: M
authors.lastname: Ghoddusi
authors.forename: Amy M
authors.initials: AM
authors.lastname: Grooters
authors.forename: Kathryn
authors.initials: K
authors.lastname: Jones
mesh_terms: D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D006736:Horses; D007167:Immunotherapy / Q000662:veterinary*; D011775:Pythium / Q000302:isolation & purification*; D012871:Skin Diseases / Q000382:microbiology / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D014612:Vaccines / Q000627:therapeutic use*
chemical_list: D014612:Vaccines