title: Clinical observation on treatment of post-craniocerebral traumatic mental disorder by integrative medicine.
abstract: OBJECTIVE
  To observe the clinical efficacy of integrative medical therapy in treating post-craniocerebral traumatic mental disorder (PCT-MD).
  
  
  METHODS
  Sixty patients with confirmed diagnosis of PCT-MD were randomly assigned to the treated group and the control group equally. All were treated by conventional comprehensive Western medicine, but to patients in the treated group, modified Xufu Zhuyu Decoction (XFZY) was additionally given and the therapeutic course for both groups was 20 days. Changes in mental symptoms were observed and recorded on the 10th and 20th day and clinical efficacy as well as cranial CT image was estimated after termination of the treatment.
  
  
  RESULTS
  The clinical effective rate in the treated group and the control group was 96.67% and 83.30% respectively. Comparison between them showed significant difference (P<0.05). Significant differences were also shown in the comparisons between the two groups in improving mental symptoms, either on the 10th or on the 20th day (P<0.05 and P<0.01 respectively), and in post-treatment cranial CT image (P<0.05).
  
  
  CONCLUSIONS
  Better efficacy could be obtained by integrative medical therapy in treating PCT-MD.
authors.affiliation: Department of Traditional Chinese Medicine, the Second Hospital Affiliated to Medical College of Zhejiang University, Hangzhou, China. kathetyluogaz@tom.com
authors.forename: Mei
authors.initials: M
authors.lastname: Sun
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Zhan
authors.forename: Chen-yu
authors.initials: CY
authors.lastname: Jin
authors.forename: Jian-zhen
authors.initials: JZ
authors.lastname: Shan
authors.forename: Shu
authors.initials: S
authors.lastname: Xu
authors.forename: Yun-lai
authors.initials: YL
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000009:adverse effects; D001523:Mental Disorders / Q000188:drug therapy*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal