[Clinical evaluation on fengweicao granule in treating benign prostatic hyperplasia].
OBJECTIVE
To report the effect of Fengweicao Granule (FWCCG), a Chinese herbal preparation made of herba Pteris multifidae, in treating benign prostatic hyperplasia (BPH).


METHODS
One hundred and fifty-five patients were assigned to two groups, the 108 patients in the treated group were administered orally with FWCG twice a day, 5 g every time; the 47 patients in the control group were treated with Proscar 5 mg per day for 3 months. The effects were evaluated by the change of the related indexes before and after treatment, including scoring by international prostatic symptom scale (I-PSS), maximum flowing rate of urine (MFR), residue urine volume (RU) in urinary bladder determined by abdominal B-ultrasonography and volume of prostate.


RESULTS
After being treated for 3 months, the I-PSS, MFR and RU improved remarkably in both groups (P <0.05 or P <0.01), but with no significant change in the volume of prostate, neither with significant difference in comparison between the two groups (P >0.05).


CONCLUSIONS
FWCG has a good effect with less adverse reaction in treating BPH.
Xue
Bo-Xin
BX
Department of Urology, Second Hospital Affiliated to Suzhou University, Jiangsu. xbxcp@hotmail.com
Shan
Yu-Xi
YX
Xiang
Gui
G
D004231:Diuresis / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D018120:Finasteride / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D011470:Prostatic Hyperplasia / Q000188:drug therapy*; D032495:Pteris
D004365:Drugs, Chinese Herbal; D004791:Enzyme Inhibitors; C550106:fengweicao; D018120:Finasteride