title: A dosimetry intercomparison phantom for intraoperative radiotherapy.
abstract: Intraoperative radiotherapy (IORT) using very low kV x-rays is a promising new treatment modality and has proven to be effective for managing breast and neurological tumours. We have treated in excess of 75 patients using four Zeiss Intrabeam x-ray sources (XRS). To date there has been no published data of any dosimetric intercomparison of this type of x-ray source used at other cancer centres worldwide. This paper describes the design of a simple dosimetry intercomparison phantom for use with these very low kV x-ray sources. A prototype polymethyl methacrylate (PMMA) phantom has been manufactured, the dimensions of which were determined by the dimensions of the XRS, the beam energy and the attenuating properties of PMMA. The phantom is used in conjunction with Gafchromic XR Type-R film (GC-XRR) and its purpose is to measure the absorbed dose at a fixed distance from the effective point source at the tip of the XRS. The utility of this phantom is further enhanced through the use of an interlock, which eliminates the need to use the mobile gantry. We have used this phantom to conduct a qualitative dosimetric intercomparison of four Zeiss Intrabeam x-ray sources with positive results. This phantom is low cost, easy to manufacture, simple to use and could be adopted as a standard method of dosimetric intercomparison for Intrabeam x-ray sources as this mode of IORT becomes more widespread.
authors.affiliation: Department of Radiation Physics, The Princess Royal Hospital, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom. kris.armoogum@nhs.net
authors.forename: Kris
authors.initials: K
authors.lastname: Armoogum
authors.forename: Colin
authors.initials: C
authors.lastname: Watson
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D009423:Nervous System Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D019047:Phantoms, Imaging; D011878:Radiotherapy / Q000295:instrumentation* / Q000379:methods*; D011879:Radiotherapy Dosage; D014965:X-Rays