title: Dietary and viscosupplementation in ankle arthritis.
abstract: Glucosamine and chondroitin sulfate are the most well-marketed dietary supplements directed toward managing symptoms associated with osteoarthritis. The presumption of their benefit in the ankle is based largely on promising results from their use in knee osteoarthritis. Likewise, viscosupplementation has proved to be efficacious in the management of osteoarthritis of the knee. Preliminary studies demonstrate a realization of this benefit in the ankle joint, but further research is required. So far, the literature has shown the dietary and viscosupplementation discussed in this article to be relatively safe for use.
authors.affiliation: Department of Orthopaedics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
authors.forename: Shaun K
authors.initials: SK
authors.lastname: Khosla
authors.forename: Judith F
authors.initials: JF
authors.lastname: Baumhauer
mesh_terms: D000843:Ankle Joint; D002809:Chondroitin Sulfates / Q000627:therapeutic use; D019587:Dietary Supplements; D005944:Glucosamine / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D010003:Osteoarthritis / Q000628:therapy*; D055676:Viscosupplementation
chemical_list: D006820:Hyaluronic Acid; D002809:Chondroitin Sulfates; D005944:Glucosamine