Catalytic asymmetric deprotonation of phosphine boranes and sulfides as a route to P-stereogenic compounds.
A comparison between phosphine boranes and sulfides in their catalytic asymmetric deprotonation using organolithiums and sub-stoichiometric amounts of (-)-sparteine has revealed superior catalytic efficiency in the phosphine sulfide deprotonation.
Gammon
Jonathan J
JJ
Department of Chemistry, University of York, Heslington, York, UK.
Canipa
Steven J
SJ
O'Brien
Peter
P
Kelly
Brian
B
Taylor
Sven
S
D001880:Boranes / Q000138:chemical synthesis*; D002384:Catalysis; D007202:Indicators and Reagents; D008094:Lithium / Q000737:chemistry; D008968:Molecular Conformation; D010720:Phosphines / Q000138:chemical synthesis*; D011522:Protons; D012997:Solvents; D013034:Sparteine / Q000737:chemistry; D013237:Stereoisomerism; D013440:Sulfides / Q000138:chemical synthesis*
D001880:Boranes; D007202:Indicators and Reagents; D010720:Phosphines; D011522:Protons; D012997:Solvents; D013440:Sulfides; D013034:Sparteine; D008094:Lithium