[Adalimumab: the molecule and manufacturing procedure].
Adalimumab is a fully human monoclonal antibody targeted toward tumor necrosis factor alpha (TNF-alpha). TNF-alpha is proinflammatory cytokine involved in the pathogenesis of many inflammatory diseases, as the psoriasis. The production process of adalimumab is complex and it is based in the called phague display technology.
Martínez de Lagrán
Z
Z
Servicio de Dermatología. Hospital de Cruces. Cruces (Vizcaya). España. ZURINE.MARTINEZDELAGRANALVAREZDEARCAYA@osakidetza.net
Pérez-Barrio
S
S
Díaz-Pérez
J L
JL
D000068879:Adalimumab; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D061067:Antibodies, Monoclonal, Humanized; D001435:Bacteriophages / Q000378:metabolism*; D001709:Biotechnology / Q000379:methods; D006801:Humans
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068879:Adalimumab