title: Quantification of blood flow velocity in stenosed arteries by the use of finite elements: an observer-independent noninvasive method.
abstract: Interventions for peripheral arterial disease should be designed to treat a physiological rather than an anatomic defect. Thus, for vascular surgeons, functional information about stenoses is as important as the anatomic one. In case of finding a stenosis by the use of magnetic resonance angiography, it would be a matter of particular interest to derive automatically and directly objective information about the hemodynamic influence on blood flow, caused by patient-specific stenoses. We developed a methodology to noninvasively perform numerical simulations of a patient's hemodynamic state on the basis of magnetic resonance images and by the means of the finite element method. We performed patient-specific three-dimensional simulation studies of the increase in systolic blood flow velocity due to stenoses using the commercial computational fluid dynamic software package FIDAP 8.52. The generation of a mesh defining the flow domain with a stenosis and some simulation results are shown.
authors.affiliation: Department of Surgery, Division of Vascular Surgery, Medical University Innsbruck, 6020 Innsbruck, Austria. h.muehlthaler@kh-schwaz.at
authors.forename: Hannes
authors.initials: H
authors.lastname: Mühlthaler
authors.forename: Bernhard
authors.initials: B
authors.lastname: Quatember
authors.forename: Gustav
authors.initials: G
authors.lastname: Fraedrich
authors.forename: Markus
authors.initials: M
authors.lastname: Mühlthaler
authors.forename: Bernhard
authors.initials: B
authors.lastname: Pfeifer
authors.forename: Andreas
authors.initials: A
authors.lastname: Greiner
authors.forename: Michael F H
authors.initials: MF
authors.lastname: Schocke
mesh_terms: D000465:Algorithms; D001157:Arterial Occlusive Diseases / Q000473:pathology* / Q000503:physiopathology*; D001783:Blood Flow Velocity; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008955:Models, Cardiovascular; D016491:Peripheral Vascular Diseases / Q000473:pathology* / Q000503:physiopathology*