title: [Uncommon retroperitoneal and bone lesions: Erdheim-Chester disease].
abstract: We report a case of Erdheim-Chester disease, revealed by a polyuropolydipsic syndrome. During the patient's work-up, osteocondensing lesions were found; the biopsy of these lesions showed an infiltration by spumous cells of histiocytic lineage, CD68+, CD1a-, associated with a lymphoid infiltrate within an extensive fibrosis. Lung and retroperitoneal lesions were discovered. The surgical resection of the involved ureter was required. Histological examination of the resected specimen showed the same pattern of histiocytic infiltration. Our case report underlines the variety of lesions associated with Erdheim-Chester disease and the importance of a complete exploration.
authors.affiliation: Laboratoire d'anatomie et de cytologie pathologiques, CHU Habib-Bourguiba, 3029 Sfax, Tunisie.
authors.forename: Héla
authors.initials: H
authors.lastname: Mnif
authors.forename: Saloua
authors.initials: S
authors.lastname: Makni
authors.forename: Lobna
authors.initials: L
authors.lastname: Ayedi
authors.forename: Walid
authors.initials: W
authors.lastname: Trigui
authors.forename: Ali
authors.initials: A
authors.lastname: Bahloul
authors.forename: Frikha
authors.initials: F
authors.lastname: Mounir
authors.forename: Tahya
authors.initials: T
authors.lastname: Sellami-Boudawara
mesh_terms: D000328:Adult; D000367:Age Factors; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D011859:Radiography; D012185:Retroperitoneal Fibrosis / Q000000981:diagnostic imaging / Q000473:pathology*