Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter.
Structural delineation and assignment are the fundamental steps in understanding the anatomy of the human brain. The white matter has been structurally defined in the past only at its core regions (deep white matter). However, the most peripheral white matter areas, which are interleaved between the cortex and the deep white matter, have lacked clear anatomical definitions and parcellations. We used axonal fiber alignment information from diffusion tensor imaging (DTI) to delineate the peripheral white matter, and investigated its relationship with the cortex and the deep white matter. Using DTI data from 81 healthy subjects, we identified nine common, blade-like anatomical regions, which were further parcellated into 21 subregions based on the cortical anatomy. Four short association fiber tracts connecting adjacent gyri (U-fibers) were also identified reproducibly among the healthy population. We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies.
Oishi
Kenichi
K
The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Zilles
Karl
K
Amunts
Katrin
K
Faria
Andreia
A
Jiang
Hangyi
H
Li
Xin
X
Akhter
Kazi
K
Hua
Kegang
K
Woods
Roger
R
Toga
Arthur W
AW
Pike
G Bruce
GB
Rosa-Neto
Pedro
P
Evans
Alan
A
Zhang
Jiangyang
J
Huang
Hao
H
Miller
Michael I
MI
van Zijl
Peter C M
PC
Mazziotta
John
J
Mori
Susumu
S
D000293:Adolescent; D000328:Adult; D000716:Anatomy, Artistic; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008488:Medical Illustration; D008875:Middle Aged