Anticoagulant induced leukoagglutination.
Low leukocyte count secondary to leukocyte aggregation caused by an ethylene diamine tetra acetic acid (EDTA) occur in both benign and malignant disorders. We report a 71-year-old male patient who was admitted to the hospital with acute chest infection. Complete blood count (CBC) collected in EDTA tube and analyzed by sysmex instrument SE/9500 revealed low hemoglobin level of 9.4g/dl, white blood cell (WBC) count of 8.2x109/L and neutrophils of 4.8x109/L. Peripheral blood smear review shows multiple leukocytes aggregation one clump in each field. When we ask for another blood sample in citrate anticoagulant, the CBC showed WBC count of 11.8x109/L and neutrophils of 6.26 x 109/L. This is a case of low leukocyte count secondary to leukocyte aggregation induced by EDTA.
Al-Amoudi
Saeed M
SM
Department of Pathology, King Fahd General Hospital, Jeddah, Kingdom of Saudi Arabia. saeed_alamoudi@hotmail.com
D000368:Aged; D000371:Agglutination / Q000187:drug effects*; D000925:Anticoagulants / Q000009:adverse effects*; D004492:Edetic Acid / Q000009:adverse effects*; D006801:Humans; D007962:Leukocytes / Q000187:drug effects*; D008297:Male
D000925:Anticoagulants; D004492:Edetic Acid