Identification of residual blood proteins in ticks by mass spectrometry proteomics.
Mass spectrometry-based proteomics of individual ticks demonstrated persistence of mammalian host blood components, including alpha- and beta-globin chains, histones, and mitochondrial enzymes, in Ixodes scapularis and Amblyomma americanum ticks for months after molting. Residual host proteins may identify sources of infection for ticks.
Wickramasekara
Samanthi
S
University of Arizona, Tucson, Arizona, USA.
Bunikis
Jonas
J
Wysocki
Vicki
V
Barbour
Alan G
AG
D000595:Amino Acid Sequence; D000818:Animals; D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D007814:Larva; D008297:Male; D051379:Mice; D018978:Molting; D009758:Nymph; D011817:Rabbits / Q000097:blood; D012756:Sheep / Q000097:blood; D053719:Tandem Mass Spectrometry; D013987:Ticks / Q000378:metabolism*
D001798:Blood Proteins