Study on analgesic effect of traditional Chinese medicine.
Chinese medicine has been used in treating pain for a long time. Much progress has been made in studies on the mechanism of the analgesic effect of Chinese medicine in animal experiments. It is found that the analgesic action may be related to the following actions: (1) Reducing the secretion of peripheral algogenic substances and inducing the secretion of pain-sensitive substances; (2) Alleviating the accumulation of local algogenic substances; (3) Increasing the release of endogenous analgesic substances; (4) Regulating c-fos gene and increasing the secretion of such substances in the central nervous system, etc. In this paper, the experimental methods and analgesic effect of Chinese medicines are reviewed.
Yu
Shan
S
Department of Chinese Medicine, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China.
Xu
Ling
L
Wei
Pin-kang
PK
Qin
Zhi-feng
ZF
Li
Jun
J
Peng
Hai-dong
HD
D000700:Analgesics / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D008516:Medicine, Chinese Traditional; D023421:Models, Animal
D000700:Analgesics; D004365:Drugs, Chinese Herbal