title: Mechanistic investigation of the gold-catalyzed aerobic oxidation of aldehydes: added insight from Hammett studies and isotopic labelling experiments.
abstract: The gold-catalyzed aerobic oxidation of aldehydes proceeds through development of a partial negative charge and has a significant kinetic isotope effect (kH/kD = 2.8-2.9), which illustrates that activation of the C-H bond takes place in the rate-determining step.
authors.affiliation: Center for Sustainable and Green Chemistry, Technical University of Denmark, Kemitorvet, DK-2800 Lyngby, Denmark. pf@kemi.dtu.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Fristrup
authors.forename: Louise
authors.initials: L
authors.lastname: Bahn Johansen
authors.forename: Claus
authors.initials: C
authors.lastname: Hviid Christensen