title: Cerebral salt wasting syndrome following neurosurgical intervention in tuberculous meningitis.
abstract: Cerebral salt wasting is characterized by inappropriate natriuresis and volume contraction in the presence of cerebral pathology. Diagnosis can be difficult and therapy is challenging. We report two children with tuberculous meningitis and hydrocephalus who developed cerebral salt wasting following neurosurgical intervention. The first patient was managed with rigorous salt and water replacement whereas the second patient required the addition of fludrocortisone for control of salt-wasting.
authors.affiliation: Pediatric Intensive Care Unit, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai 400 022, India. nagotkar.leena@gmail.com
authors.forename: L
authors.initials: L
authors.lastname: Nagotkar
authors.forename: P
authors.initials: P
authors.lastname: Shanbag
authors.forename: N
authors.initials: N
authors.lastname: Dasarwar
mesh_terms: D001921:Brain / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery*; D007010:Hyponatremia / Q000175:diagnosis / Q000652:urine; D008297:Male; D011183:Postoperative Complications; D012964:Sodium / Q000378:metabolism*; D014390:Tuberculosis, Meningeal / Q000601:surgery*; D019282:Wasting Syndrome / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism*
chemical_list: D012964:Sodium