Clinicopathologic characteristics of gastric cancer patients who underwent noncurative gastrectomy with long-term survival.
OBJECTIVE
To demonstrate clinicopathologic characteristics of gastric cancer patients who underwent noncurative gastrectomy with long-term survival.


METHODS
We retrospectively reviewed 202 advanced gastric cancer patients who underwent noncurative gastrectomy.


RESULTS
The long-term survivors who survived for more than 3 years comprised four of 65 patients with a residual tumor in the peritoneum, one of 50 patients with a residual tumor from lymph node metastasis, three of 41 patients positive for the resected margin (M-factor) and 17 of 153 patients with free intraperitoneal cancer cells (Cy-factor). Multivariate analysis indicated that independent indicators affecting survival were lymph node metastasis and peritoneal metastasis in patients with the Cy-factor and histology in patients with the M-factor.


CONCLUSIONS
Long-term survival can only be expected in patients with the Cy-factor who have neither macroscopic peritoneal metastasis nor lymph node metastasis or in patients with the M-factor who have a well-differentiated tumor.
Saito
Hiroaki
H
Department of Surgery, Division of Surgical Oncology, Tottori University School of Medicine, 36-1 Nishi-cho, Yonago, 683-8504, Japan. sai10@grape.med.tottori-u.ac.jp
Yamada
Yoshinori
Y
Tsujitani
Shunichi
S
Ikeguchi
Masahide
M
D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007564:Japan; D053208:Kaplan-Meier Estimate; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness / Q000473:pathology; D018365:Neoplasm, Residual / Q000401:mortality / Q000473:pathology*; D010166:Palliative Care; D010534:Peritoneal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000556:secondary*; D011379:Prognosis; D012189:Retrospective Studies; D013223:Statistics as Topic; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D017741:Survivors