title: [Acute CSF changes in the mesencephalon aqueduct after subarachnoid hemorrhage as measured by PC-MRI].
abstract: OBJECTIVE
  Determining acute intracranial hydrodynamic changes after subarachnoid hemorrhage through an analysis of the CSF stroke volume (SV) as measured by phase-contrast MRI (PC-MRI) in the mesencephalon aqueduct.
  
  
  METHODS
  A prospective study was performed in 33 patients with subarachnoid hemorrhage. A PC-MRI imaging study was performed n the acute phase (< 48 hours). CSF flow was measured in the aqueduct. The appearance of acute hydrocephalus (HCA) was then compared with data on CSF flow, and the location of the intraventricular and perimesencephalic bleeding.
  
  
  RESULTS
  CSF analysis was performed on 27 patients, 11 of whom presented with an acute HCA. All 11 patients had an abnormal SV in the aqueduct: patients with a communicating HCA had an increased SV (n=8); and patients with a noncommunicating HCA had a nil SV (n=3). Patients with a normal SV in the aqueduct did not develop an acute HCA. Intraventricular bleeding significantly led to HCA (P=0.02), which was of the communicating type in 70% of cases.
  
  
  CONCLUSIONS
  Subarachnoid hemorrhage leads to intracranial CSF hydrodynamic modifications in the aqueduct in the majority of patients. CSF flow can help us to understand the mechanism of the appearance of acute HCA. Indeed, hydrocephalus occurred - of the communicating type in most cases - even in the presence of intraventricular bleeding.
authors.affiliation: Service de neurologie, hôpital de Bicêtre, 94275 Kremlin-Bicêtre cedex, France. guillaume.saliou@bct.aphp.fr
authors.forename: G
authors.initials: G
authors.lastname: Saliou
authors.forename: O
authors.initials: O
authors.lastname: Balédent
authors.forename: P
authors.initials: P
authors.lastname: Lehmann
authors.forename: G
authors.initials: G
authors.lastname: Paradot
authors.forename: C
authors.initials: C
authors.lastname: Gondry-Jouet
authors.forename: R
authors.initials: R
authors.lastname: Bouzerar
authors.forename: G
authors.initials: G
authors.lastname: Devisme
authors.forename: M
authors.initials: M
authors.lastname: Theaudin
authors.forename: H
authors.initials: H
authors.lastname: Deramond
authors.forename: D
authors.initials: D
authors.lastname: Le Gars
authors.forename: M-E
authors.initials: ME
authors.lastname: Meyer
authors.forename: J-N
authors.initials: JN
authors.lastname: Vallée
mesh_terms: D000208:Acute Disease; D002535:Cerebral Aqueduct / Q000473:pathology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008636:Mesencephalon / Q000473:pathology*; D008875:Middle Aged; D011446:Prospective Studies; D013345:Subarachnoid Hemorrhage / Q000134:cerebrospinal fluid* / Q000473:pathology