Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis Study (KIDS).
Atopic dermatitis (AD) is a multifactorial disease that usually decreases the quality of life of affected patients. The purpose of this study was to evaluate the associated factors for atopic dermatitis, asthma, rhinitis, and food allergy by physical examination of the skin and a questionnaire in nursery school children in Ishigaki Island, Okinawa, Japan. Enrolled in this study were 460 children from 0 to 6 years of age. Physical examination of skin symptoms and blood tests were performed. Information on past history and family history of atopic dermatitis, asthma, rhinitis, and food allergy were collected by questionnaire. The prevalence of atopic dermatitis was 12.2% (56/460). The cumulative prevalence of asthma, rhinitis, and food allergy was 19.9% (91/458), 3.3% (15/457), and 5.5% (25/456), respectively. In multivariate analysis, maternal history of rhinitis, atopic dermatitis siblings, past history of asthma and food allergy, and elevation of total IgE were significantly related to atopic dermatitis. A high total IgE level was a strong risk factor specific for atopic dermatitis in this population.
Fukiwake
Noriko
N
Department of Dermatology, Kyushu University Hospital, Maidashi 3-1-1, Higashiku, Fukuoka, Japan.
Furusyo
Norihiro
N
Takeoka
Hiroaki
H
Toyoda
Kazuhiro
K
Kubo
Norihiko
N
Kido
Makiko
M
Hayashida
Sayaka
S
Uchi
Hiroshi
H
Moroi
Yoichi
Y
Urabe
Kazunori
K
Kinukawa
Naoko
N
Nose
Yoshiaki
Y
Hayashi
Jun
J
Furue
Masutaka
M
D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007223:Infant; D007564:Japan; D012307:Risk Factors