Pattern of dyslipidaemia among Nigerians with type 2 diabetes mellitus.
OBJECTIVE
To characterize the pattern of lipid profile abnormalities among Nigerians with type 2 diabetes mellitus attending the Diabetes clinic of a tertiary referral centre in Nigeria.


METHODS
A cross sectional analysis of 192 diabetic patients consecutively recruited from patients attending the Diabetes clinic and 52 volunteering non-diabetic and non-hypertensive controls was undertaken. The main outcome measures were lipid profile and anthropometric indices. Data analysis was done with SPSS version 10. Results were expressed as mean +/- SD. Differences between groups were regarded as significant atp < 0.05. Comparisons of means, test of association were done using independent t-test, chi-square test and bivariate (Pearson's) correlation analysis.


RESULTS
Eighty-nine percent of the patients had at least one abnormal lipid profile while 64.5% had combined dyslipidaemia. Reduced HDL-C and raised TG constituted the most (88.0%) and least (25.0%) prevalent abnormalities respectively. Significant difference in the mean values of HDL-C and LDL-C was observed between the patients and controls.


CONCLUSIONS
Dyslipidaemia is common among patients with type 2 diabetes mellitus in Nigeria with majority of the patients having a combined dyslipidaemia. There is therefore the need to pay great attention to the lipid parameters in Nigerians with type 2 diabetes mellitus.
Okafor
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Endocrinology, Unit, Department of Medicine, Lagos University Teaching Hospital, Idi-Araba, Lagos. glochris2@yahoo.com
Fasanmade
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Oke
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D050171:Dyslipidemias / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence
D008055:Lipids