title: Pulsed-arterial-spin-labeling perfusion 3T MRI following single seizure: a first case report study.
abstract: A 41-year-old woman with focal epilepsy was analyzed immediately and 1 week post-ictally using pulsed-arterial-spin-labeling perfusion 3T MRI, a non-invasive method. Seizure-associated blood flow alterations were characterized by increased ictal perfusion in the occipito-parietal right cortex, and hypoperfusion in the same location 1 week later. These results indicate that non-invasive perfusion MRI can be used routinely to detect vascular alterations in epilepsy, and possibly to identify the location of the seizure focus.
authors.affiliation: Service of Neuroradiology, Verona City Hospital, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Pizzini
authors.forename: Paolo
authors.initials: P
authors.lastname: Farace
authors.forename: Tiziano
authors.initials: T
authors.lastname: Zanoni
authors.forename: Stefano
authors.initials: S
authors.lastname: Magon
authors.forename: Alberto
authors.initials: A
authors.lastname: Beltramello
authors.forename: Andrea
authors.initials: A
authors.lastname: Sbarbati
authors.forename: Paolo F
authors.initials: PF
authors.lastname: Fabene
mesh_terms: D000328:Adult; D001158:Arteries; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology; D004827:Epilepsy / Q000175:diagnosis*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D019275:Radiopharmaceuticals; D013113:Spin Labels
chemical_list: D019275:Radiopharmaceuticals; D013113:Spin Labels