[Obstructive sleep apnea syndrome and cardiovascular diseases].
Obstructive sleep apnea (OSA) syndrome is one of the most common respiratory disorders in humans. There is emerging evidence linking OSA to vascular disease, particularly hypertension. The underlying pathophysiological mechanisms that link OSA to cardiovascular diseases such as hypertension, congestive heart failure and atrial fibrillation are not entirely understood, although they certainly include mechanical events, increased sympathetic activity and oxidative stress. This review will examine the evidence and mechanisms linking OSA syndrome to cardiovascular disease.
Bentivoglio
Maurizio
M
Cardiologia e Fisiopatologia Cardiovascolare, Università e Azienda Ospedaliera di Perugia.
Bergamini
Eva
E
Fabbri
Marta
M
Andreoli
Chiara
C
Bartolini
Claudia
C
Cosmi
Deborah
D
Capasso
Vincenzo
V
Bottini
Paolo
P
Ambrosio
Giuseppe
G
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology; D015331:Cohort Studies; D045422:Continuous Positive Airway Pressure; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress; D017286:Polysomnography; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy