title: Total synthesis of the originally proposed and revised structures of scleritodermin A.
abstract: The first total synthesis of the originally proposed and revised structure of scleritodermin A, along with an isomer, were achieved by the use of an alpha-azido carboxyl group serving as the key alpha-ketoamide precursor, thus leading to a revision of the structure originally proposed for natural scleritodermin A.
authors.affiliation: Chinese National Center for Drug Screening, State Key Laboratory of Drug Research Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guoshoujing Road, Zhangjiang Hi-Tech Park, Shanghai 201203,China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Liu
authors.forename: Yong-Mei
authors.initials: YM
authors.lastname: Cui
authors.forename: Fa-Jun
authors.initials: FJ
authors.lastname: Nan
mesh_terms: D000577:Amides / Q000737:chemistry; D007536:Isomerism; D007659:Ketones / Q000737:chemistry; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000577:Amides; D007659:Ketones; D010456:Peptides, Cyclic; C484931:scleritodermin A