title: Approach to diagnosis and pathological examination in bronchial Dieulafoy disease: a case series.
abstract: BACKGROUND
  There are limited series concerning Dieulafoy disease of the bronchus. We describe the clinical presentation of a series of 7 patients diagnosed with Dieulafoy disease of the bronchus and provide information about the pathological diagnosis approach.
  
  
  METHODS
  A retrospective review of patients who underwent surgery for massive and unexplained recurrent hemoptysis in a referral center during a 11-year period.
  
  
  RESULTS
  Seven heavy smoker (49 pack years) patients (5 males) mean aged 54 years experienced a massive hemoptysis (350-1000 ml) unrelated to a known lung disease and frequently recurrent. Bronchial contrast extravasation was observed in 3 patients, combining both CT scan and bronchial arteriography. Efficacy of bronchial artery embolization was achieved in 40% of cases before surgery. Pathological examination demonstrated a minute defect in 3 cases and a large and dysplasic superficial bronchial artery in the submucosa in all cases.
  
  
  CONCLUSIONS
  Dieulafoy disease should be suspected in patients with massive and unexplained episodes of recurrent hemoptysis, in order to avoid hazardous endoscopic biopsies and to alert the pathologist if surgery is performed.
authors.affiliation: Service de Pneumologie et Unité de Réanimation Médicale, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris and Université Pierre et Marie Curie, Paris, France. antoine.parrot@tnn.ap-hop-paris.fr
authors.forename: Antoine
authors.initials: A
authors.lastname: Parrot
authors.forename: Martine
authors.initials: M
authors.lastname: Antoine
authors.forename: Antoine
authors.initials: A
authors.lastname: Khalil
authors.forename: Jonathan
authors.initials: J
authors.lastname: Théodore
authors.forename: Gilles
authors.initials: G
authors.lastname: Mangiapan
authors.forename: Bernard
authors.initials: B
authors.lastname: Bazelly
authors.forename: Muriel
authors.initials: M
authors.lastname: Fartoukh
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D001981:Bronchial Arteries / Q000473:pathology* / Q000601:surgery; D001982:Bronchial Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D001999:Bronchoscopy; D004621:Embolization, Therapeutic; D005260:Female; D006469:Hemoptysis / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D014662:Vasoconstrictor Agents