title: Molecular characterization of highly virulent fowl adenoviruses associated with outbreaks of inclusion body hepatitis.
abstract: Restriction enzyme analysis of DNA was used to characterize fowl adenoviruses (FAVs) consistently associated with outbreaks of acute inclusion body hepatitis. When low doses of these FAVs were administered via a natural route to chickens they caused IBH. A strong genomic relationship was demonstrated between these virulent FAVs. In contrast, the genomes of serologically related, but non-virulent or mildly virulent FAVs were found to differ substantially from those of the virulent FAVs.
authors.affiliation: CSIRO Division of Animal Health, Animal Health Research Laboratory, P.O. Parkville, Victoria, Australia.
authors.forename: K M
authors.initials: KM
authors.lastname: Erny
authors.forename: D A
authors.initials: DA
authors.lastname: Barr
authors.forename: K J
authors.initials: KJ
authors.lastname: Fahey