title: [Preparation of a brochure for patients undergoing FOLFIRI chemotherapy based on survey of adverse reactions].
abstract: We have retrospectively been collecting data on adverse reactions to FOLFIRI chemotherapy in our hospital from September 2005 to August 2006, by electronic medical records. The retrospective study was of 67 patients who received FOLFIRI for advanced colorectal cancer. Survey results showed high incidences of vomiting(58.2%), anorexia(91.4%), constipation (47.8%), diarrhea (61.2%) and alopecia(71.6%). The first cycle using FOLFIRI therapy, vomiting (20.9%), anorexia(53.7%), constipation ( 14.9%), and diarrhea (23.9%)were observed. We sought to minimize inter-individual differences in pharmaceutical care and drug consultation by clinical pharmacists and to ensure the accurate understanding of patients. We are sure that this kind of activity will help us to provide better pharmaceutical care for patients.
authors.affiliation: Dept. of Pharmacy, Cancer Institute Hospital.
authors.forename: Kayoko
authors.initials: K
authors.lastname: Kamisugi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Matsusaka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imada
authors.forename: Daigo
authors.initials: D
authors.lastname: Shoji
authors.forename: Eri
authors.initials: E
authors.lastname: Nakamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Yokokawa
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Kawakami
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Hirata
authors.forename: Kazumi
authors.initials: K
authors.lastname: Nawano
authors.forename: Megumi
authors.initials: M
authors.lastname: Ogawa
authors.forename: Eiji
authors.initials: E
authors.lastname: Shinozaki
authors.forename: Mitsukuni
authors.initials: M
authors.lastname: Suenaga
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Mizunuma
authors.forename: Kiyohiko
authors.initials: K
authors.lastname: Hatake
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Hama
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use*; D002166:Camptothecin / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D003248:Constipation / Q000139:chemically induced; D003967:Diarrhea / Q000139:chemically induced; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000627:therapeutic use; D006306:Health Surveys; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010174:Pamphlets
chemical_list: D002955:Leucovorin; D005472:Fluorouracil; D002166:Camptothecin