Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder.
Little is known about whether the clinical correlates of hoarding behavior are different in men and women with obsessive-compulsive disorder (OCD). In the current study, we evaluated the association of hoarding with categories of obsessions and compulsions, psychiatric disorders, personality dimensions, and other clinical characteristics separately in 151 men and 358 women with OCD who were examined during the OCD Collaborative Genetics Study. We found that, among men but not women, hoarding was associated with aggressive, sexual, and religious obsessions and checking compulsions. In men, hoarding was associated with generalized anxiety disorder and tics whereas, among women, hoarding was associated with social phobia, post-traumatic stress disorder, body dysmorphic disorder, nail biting, and skin picking. In women but not men, hoarding was associated with schizotypal and dependent personality disorder dimensions, and with low conscientiousness. These findings indicate that specific clinical correlates of hoarding in OCD are different in men and women and may reflect sex-specific differences in the course, expression, and/or etiology of hoarding behavior in OCD.
Samuels
Jack F
JF
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer 4-181, Baltimore, MD 21287-7228, USA. jacks@jhmi.edu
Bienvenu
O Joseph
OJ
Pinto
Anthony
A
Murphy
Dennis L
DL
Piacentini
John
J
Rauch
Scott L
SL
Fyer
Abby J
AJ
Grados
Marco A
MA
Greenberg
Benjamin D
BD
Knowles
James A
JA
McCracken
James T
JT
Cullen
Bernadette
B
Riddle
Mark A
MA
Rasmussen
Steven A
SA
Pauls
David L
DL
Liang
Kung-Yee
KY
Hoehn-Saric
Rudolf
R
Pulver
Ann E
AE
Nestadt
Gerald
G
D000203:Activities of Daily Living / Q000523:psychology*; D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000523:psychology*; D012720:Severity of Illness Index; D012737:Sex Factors; D012725:Sexual Behavior / Q000523:psychology*