Recent developments in analytical determination of furosemide.
Furosemide (FUR), a drug that promotes urine excretion, is used in the pharmacotherapy of various diseases and is considered as a doping agent in sports. FUR is a powerful diuretic (water pill). This medicine is used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, and nephrotic syndrome. Owing to its extensive use as a powerful diuretic, FUR has long attracted the attention of many analysts. A variety of analytical methods have been proposed for the determination of FUR in biological fluids and pharmaceutical samples. The revision includes the most relevant analytical methodologies used in its determination from the nineties decade at present.
Espinosa Bosch
M
M
Department of Pharmacy, General Hospital, University Hospital "Virgen del Rocío", Manuel Siurot s/n, 41013 Sevilla, Spain.
Ruiz Sánchez
A J
AJ
Sánchez Rojas
F
F
Bosch Ojeda
C
C
D002623:Chemistry Techniques, Analytical / Q000379:methods*; D004232:Diuretics / Q000032:analysis* / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods; D005665:Furosemide / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D049449:Luminescence; D008163:Luminescent Measurements / Q000379:methods; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence / Q000379:methods; D017186:Titrimetry / Q000379:methods
D004232:Diuretics; D005665:Furosemide