New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007.
This review summarizes selected articles appearing from January to December 2007 in the Journal of Allergy and Clinical Immunology. Articles were chosen that related to advances in mechanisms of chronic allergic inflammation and asthma, including those describing gene association studies, mast cells, IgE, eosinophils, cytokines, the inception of allergy, airway remodeling, preclinical therapeutic targets, and virally induced asthma.
Broide
David
D
Department of Medicine, University of California San Diego, La Jolla, CA 92093-0635, USA. dbroide@ucsd.edu
D000818:Animals; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D016207:Cytokines / Q000276:immunology / Q000378:metabolism; D004804:Eosinophils / Q000276:immunology* / Q000378:metabolism; D000091344:Filaggrin Proteins; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D007073:Immunoglobulin E / Q000097:blood; D007249:Inflammation / Q000235:genetics / Q000276:immunology; D007381:Intermediate Filament Proteins / Q000276:immunology / Q000378:metabolism; D008407:Mast Cells / Q000276:immunology* / Q000378:metabolism; D011110:Polymorphism, Genetic; D011968:Receptors, Histamine / Q000276:immunology / Q000378:metabolism; D012141:Respiratory Tract Infections / Q000150:complications; D012907:Smoking; D018418:Th2 Cells / Q000276:immunology* / Q000378:metabolism; D014777:Virus Diseases / Q000150:complications
D018926:Anti-Allergic Agents; D016207:Cytokines; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins; D011968:Receptors, Histamine; D007073:Immunoglobulin E