title: New Flavonoids from Boldoa purpurascens Cav.
abstract: Phytochemical analysis of the leaves of BOLDOA PURPURASCENS Cav. led to isolation of four flavone glycosides, three of which are new compounds. Their structures have been determined by mass spectrometry and by 1 D and 2 D NMR analysis, i. e., 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-alpha- L-rhamnopyranosyl-(1-->2)-beta- D-xylopyranoside ( 1), 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-beta- D-xylopyranoside ( 2), and 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-alpha- L-rhamnopyranosyl-(1-->2)-beta- D-glucopyranoside ( 3). The known compound was 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-beta- D-glucopyranoside ( 4). The aglycone 4',5-dihydroxy-6,7-methylenedioxyflavonol is known as gomphrenol. Compounds 1 and 2 failed to show antifungal activity when tested against three different strains of fungi, i. e., FUSARIUM CULMORUM, BOTRYTIS CINEREA, and ASPERGILLUS FLAVUS.
authors.affiliation: Department of Pharmacy at Marta Abreu University, Road to Camajuani, Santa Clara, Cuba.
authors.forename: Dulce María
authors.initials: DM
authors.lastname: Mosquera
authors.forename: Amuri
authors.initials: A
authors.lastname: Kilonda
authors.forename: Suzanne
authors.initials: S
authors.lastname: Toppet
authors.forename: Frans
authors.initials: F
authors.lastname: Compernolle
authors.forename: Wim
authors.initials: W
authors.lastname: Dehaen
authors.forename: Isabelle E
authors.initials: IE
authors.lastname: François
authors.forename: Bruno P
authors.initials: BP
authors.lastname: Cammue
authors.forename: Sandra
authors.initials: S
authors.lastname: Apers
authors.forename: Luc
authors.initials: L
authors.lastname: Pieters
authors.forename: Armando Cuéllar
authors.initials: AC
authors.lastname: Cuéllar
mesh_terms: D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects*; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D019906:Nuclear Magnetic Resonance, Biomolecular; D039281:Nyctaginaceae / Q000737:chemistry*
chemical_list: D005419:Flavonoids