title: Both layers of the COPII coat come into view.
abstract: Anterograde transport in the early secretory pathway is mediated by COPII-coated vesicles. Stagg et al. (2008) have now visualized the double-layered COPII coat using electron cryomicroscopy, providing insight into how coats are assembled to accommodate cargo of different sizes.
authors.affiliation: Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
authors.forename: Frederick M
authors.initials: FM
authors.lastname: Hughson
mesh_terms: D020285:Cryoelectron Microscopy; D006801:Humans; D008958:Models, Molecular; D021381:Protein Transport; D033921:Vesicular Transport Proteins / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D033921:Vesicular Transport Proteins