title: Inpatient preseptal cellulitis: experience from a tertiary eye care centre.
abstract: OBJECTIVE
  To describe causes of preseptal cellulitis (PSC) and outcome of treatment in patients admitted to a tertiary eye-care centre.
  
  
  METHODS
  A 15-year (January 1991 to December 2005) review of inpatients with clinical signs and symptoms or radiological evidence suggestive of PSC was conducted. Patients with infection anterior to the orbital septum which is characterised by acute onset of eyelid oedema, tenderness, erythema, warmth and chemosis were included in the study.
  
  
  RESULTS
  Among the 104 patients (male:female 64:40) fulfilling the diagnostic criteria for PSC, acute dacryocystitis (ADC) was the most common predisposing cause in 32.6% patients, followed by sinusitis/upper-respiratory infection (URI) in 28.8% and trauma/recent surgery in 27.8% patients. Fifty-per cent required surgical intervention including dacryocystorhinostomy/probing/stenting in 74% and abscess/chalazian drainage in 28.8%. In 38.5% of the patients who had surgical intervention, microbiological investigations were carried out, cultures were positive in 90%. Most common micro-organisms recovered included Staphylococcus and Streptococcus species followed by Haemophilus influenzae and Klebsiella pneumonia. Blood cultures were positive in two of the 34 patients in whom blood was drawn. Most patients responded to systemic antibiotics with resolution of PSC. Seven patients developed late complications which included subacute lid abscesses, eyelid necrosis and cicatricial ectropion.
  
  
  CONCLUSIONS
  Sinusitis/URI, ADC and recent history of trauma/surgery were the most common cause of PSC in admitted patients. Although most patients responded to systemic antibiotics, surgical intervention was necessary in some patients to prevent associated complications.
authors.affiliation: Oculoplastic and Orbit Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. orbitdr@yahoo.com
authors.forename: I A
authors.initials: IA
authors.lastname: Chaudhry
authors.forename: F A
authors.initials: FA
authors.lastname: Shamsi
authors.forename: E
authors.initials: E
authors.lastname: Elzaridi
authors.forename: W
authors.initials: W
authors.lastname: Al-Rashed
authors.forename: A
authors.initials: A
authors.lastname: Al-Amri
authors.forename: Y O
authors.initials: YO
authors.lastname: Arat
mesh_terms: D000038:Abscess / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D004322:Drainage / Q000379:methods; D005141:Eyelid Diseases / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D005260:Female; D006192:Haemophilus Infections / Q000382:microbiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D012720:Severity of Illness Index; D013203:Staphylococcal Infections / Q000382:microbiology; D013290:Streptococcal Infections / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents