The increased degradation of NAT-H28Y mutant protein is due to a reduced interaction with 14-3-3.
Huang
Z
Z
Chattoraj
A
A
Li
X
X
Snyder
S H
SH
Borjigin
J
J
D048948:14-3-3 Proteins / Q000378:metabolism*; D019943:Amino Acid Substitution; D000818:Animals; D047068:Arylalkylamine N-Acetyltransferase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D006801:Humans; D055550:Protein Stability; D051381:Rats; D020332:Rats, Inbred LEC
D048948:14-3-3 Proteins; C520223:Aanat protein, rat; D047068:Arylalkylamine N-Acetyltransferase