title: A conserved mutation in an ethylene biosynthesis enzyme leads to andromonoecy in melons.
abstract: Andromonoecy is a widespread sexual system in angiosperms characterized by plants carrying both male and bisexual flowers. In melon, this sexual form is controlled by the identity of the alleles at the andromonoecious (a) locus. Cloning of the a gene reveals that andromonoecy results from a mutation in the active site of 1-aminocyclopropane-1-carboxylic acid synthase. Expression of the active enzyme inhibits the development of the male organs and is not required for carpel development. A causal single-nucleotide polymorphism associated with andromonoecy was identified, which suggests that the a allele has been under recent positive selection and may be linked to the evolution of this sexual system.
authors.affiliation: INRA (Institut National de la Recherche Agronomique)-CNRS, UMR1165, Unité de Recherche en Génomique Végétale, 2 rue Gaston Crémieux, F-91057 Evry, France.
authors.forename: Adnane
authors.initials: A
authors.lastname: Boualem
authors.forename: Mohamed
authors.initials: M
authors.lastname: Fergany
authors.forename: Ronan
authors.initials: R
authors.lastname: Fernandez
authors.forename: Christelle
authors.initials: C
authors.lastname: Troadec
authors.forename: Antoine
authors.initials: A
authors.lastname: Martin
authors.forename: Halima
authors.initials: H
authors.lastname: Morin
authors.forename: Marie-Agnes
authors.initials: MA
authors.lastname: Sari
authors.forename: Fabrice
authors.initials: F
authors.lastname: Collin
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Flowers
authors.forename: Michel
authors.initials: M
authors.lastname: Pitrat
authors.forename: Michael D
authors.initials: MD
authors.lastname: Purugganan
authors.forename: Catherine
authors.initials: C
authors.lastname: Dogimont
authors.forename: Abdelhafid
authors.initials: A
authors.lastname: Bendahmane
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D001665:Binding Sites; D005075:Biological Evolution; D003433:Crosses, Genetic; D028463:Cucumis melo / Q000201:enzymology* / Q000235:genetics / Q000502:physiology*; D035264:Flowers / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D017343:Genes, Plant; D006239:Haplotypes; D008190:Lyases / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D009154:Mutation; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012641:Selection, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D008190:Lyases; C021773:1-aminocyclopropanecarboxylate synthase