title: Ovarian reserve evaluation: state of the art.
abstract: OBJECTIVE
  Revise role of hormonal basal and dynamic tests, as well as ultrasonographic measures as ovarian reserve markers, in order to provide better counseling to subfertile couples.
  
  
  METHODS
  Review of publications on the topic, with an emphasis on recent well designed articles.
  
  
  RESULTS
  Currently available ovarian reserve tests do not provide sufficient evidence to be solely considered ideal, even for premature ovarian senescence patients who do not present subfertility complaints. However, these markers occupy important place in initial approach to treatment of subfertile couples, predicting unsatisfactory results that could be improved by differentiated induction schemes and reducing excessive psychological and financial burdens, and adverse effects.
  
  
  CONCLUSIONS
  In order to remedy the limitations due to the scarcity of strong evidence about this topic, future studies should try to clarify predictive value of markers in groups of specific diseases-related subfertility and pay special attention to propaedeutic multivariate models including anti-Müllerian hormone and antral follicle count.
authors.affiliation: Sector of Human Reproduction, Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil. bramalho@usp.br
authors.forename: Bruno Ramalho
authors.initials: BR
authors.lastname: de Carvalho
authors.forename: Ana Carolina Japur de Sá
authors.initials: AC
authors.lastname: Rosa e Silva
authors.forename: Júlio César
authors.initials: JC
authors.lastname: Rosa e Silva
authors.forename: Rosana Maria
authors.initials: RM
authors.lastname: dos Reis
authors.forename: Rui Alberto
authors.initials: RA
authors.lastname: Ferriani
authors.forename: Marcos Felipe
authors.initials: MF
authors.lastname: Silva de Sá
mesh_terms: D054304:Anti-Mullerian Hormone / Q000378:metabolism; D016922:Cellular Senescence; D002996:Clomiphene / Q000494:pharmacology; D004958:Estradiol / Q000378:metabolism; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006801:Humans; D007265:Inhibins / Q000378:metabolism; D008297:Male; D006080:Ovarian Follicle / Q000378:metabolism; D010050:Ovarian Function Tests / Q000379:methods*; D010053:Ovary / Q000502:physiology*; D016649:Primary Ovarian Insufficiency / Q000628:therapy; D014463:Ultrasonography / Q000379:methods
chemical_list: D005300:Fertility Agents, Female; C422364:inhibin B; D002996:Clomiphene; D004958:Estradiol; D007265:Inhibins; D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone