Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform.
We demonstrate in vivo volumetric bidirectional blood flow imaging in animal models using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image half-planes, enabling volumetric bidirectional flow mapping without manual segmentation.
Tao
Yuankai K
YK
Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA. yt13@duke.edu
Davis
Anjul M
AM
Izatt
Joseph A
JA
D000465:Algorithms; D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology*; D002642:Chick Embryo; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D051379:Mice; D012212:Rheology / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*