title: Unifying statistical classification and geodesic active regions for segmentation of cardiac MRI.
abstract: This paper presents a segmentation method that extends geodesic active region methods by the incorporation of a statistical classifier trained using feature selection. The classifier provides class probability maps based on class representative local features, and the geodesic active region formulation enables the partitioning of the image according to the region information. We demonstrate automatic segmentation results of the myocardium in cardiac late gadolinium-enhanced magnetic resonance imaging (CE-MRI) data using coupled level set curve evolutions, in which the classifier is incorporated both from a region term and from a shape term from particle filtering. The results show potential for clinical studies of scar tissue in late CE-MRI data.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. jenny@bwh.harvard.edu
authors.forename: Jenny
authors.initials: J
authors.lastname: Folkesson
authors.forename: Eigil
authors.initials: E
authors.lastname: Samset
authors.forename: Raymond Y
authors.initials: RY
authors.lastname: Kwong
authors.forename: Carl-Fredrik
authors.initials: CF
authors.lastname: Westin
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D006321:Heart / Q000033:anatomy & histology*; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008955:Models, Cardiovascular; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity