50 grams glucose challenge test for screening of gestational diabetes mellitus in each trimester in potential diabetic pregnancy.
OBJECTIVE
To evaluate the cutoff value of the 50 grams glucose challenge test (GCT) for screening of gestational diabetes mellitus (GDM) in each trimester in potential diabetic pregnancy and to determine the prevalence of GDM.


METHODS
Retrospective descriptive study (Diagnostic test).


METHODS
Section of Obstetrics and Gynecology, Taksin Hospital.


METHODS
Two thousand and ten potential diabetic pregnant women who attended the antenatal care clinic at Taksin Hospital between August 2004 and December 2005 were identified and recruited based on risk indicators.


METHODS
A GCT was performed If GCT was positive, 100 grams oral glucose tolerance test (OGTT) was done to confirm the GDM. All relevant data including demographic information, GCT and OGTT results were collected The receiver operating characteristic (ROC) curve was used to identify the cutoff value of GCT for screening of GDM.


METHODS
The cutoff value of GCT for screening of GDM in each trimester by using ROC curve.


RESULTS
The cutoff values of GCT in 1st, 2nd, 3rd, and all trimesters were 179, 177, 184, and 179 mg/dl respectively The authors recommended 177 mg/dl as the cutoff value of GCT for screening of GDM in potential diabetic pregnancy in each trimester The prevalence of GDM in 1st, 2nd, 3rd, and all trimesters were 14.22, 13.04, 11.96, and 13.2% respectively.


CONCLUSIONS
The threshold of 177 mg/dl was recommended as the cutoff value of GCT for screening of GDM in each trimester in potential diabetic pregnancy. The prevalence was 13.2%.
Punthumapol
Chanvitya
C
Section of Obstetrics and Gynecology, Taksin Hospital, Bangkok, Thailand.
Tekasakul
Putthawan
P
D016640:Diabetes, Gestational / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D005951:Glucose Tolerance Test / Q000706:statistics & numerical data*; D006801:Humans; D008403:Mass Screening; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D015995:Prevalence; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013785:Thailand / Q000453:epidemiology