title: [Intelligence development in children with early-onset epilepsy with complex partial seizures].
abstract: OBJECTIVE
  Eighty-four outpatients treated for epilepsy with complex partial seizures were followed up 18 years later.
  
  
  RESULTS
  Of these Patients, 35% showed stabile learning disabilities when they were first treated and also 18 years later. These Patients did not achieve a regular school qualification. Forty-eight percent suffered from a psychiatric disorder as classified by the ICD-10. Children with a pathological neurological result in the first examination showed poorer cognitive outcomes than Patients with only mild neurological impairment. The age of onset of the disease did not significantly predict subsequent cognitive abilities. Patients who showed complex partial seizures and generalized seizures showed poorer cognitive outcomes, as did Patients with a psychiatric disorder or psychosocial problems.
  
  
  CONCLUSIONS
  The study points to the importance of a conjoint neurological and psychiatric treatment to deal with the different impairments and corresponding developmental course of the disease.
authors.affiliation: Kinderklinik Siegen, Wellersbergstrasse 60, 57072, Siegen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Pott
authors.forename: M
authors.initials: M
authors.lastname: Heyken
authors.forename: H
authors.initials: H
authors.lastname: Remschmidt
mesh_terms: D000293:Adolescent; D002648:Child; D003072:Cognition Disorders / Q000453:epidemiology*; D015897:Comorbidity; D004828:Epilepsies, Partial / Q000453:epidemiology*; D004827:Epilepsy / Q000453:epidemiology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007360:Intelligence; D001523:Mental Disorders / Q000453:epidemiology*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D055815:Young Adult