Identification of the nukacin KQU-131, a new type-A(II) lantibiotic produced by Staphylococcus hominis KQU-131 isolated from Thai fermented fish product (Pla-ra).
Staphylococcus hominis KQU-131, isolated from Thai fermented marine fish, produces a heat stable bacteriocin. Structural and genetic analysis indicated that the bacteriocin is a variant of nukacin ISK-1, a type-A(II) lantibiotic, and we termed the bacteriocin nukacin KQU-131. There were three different amino acid residues between nukacin ISK-1 and nukacin KQU-131, one residue in the leader peptide and the other two in the mature peptide.
Wilaipun
Pongtep
P
Department of Fishery Products, Faculty of Fisheries, Kasetsart University, Chatuchak, Bangkok, Thailand.
Zendo
Takeshi
T
Okuda
Ken-ichi
K
Nakayama
Jiro
J
Sonomoto
Kenji
K
D000595:Amino Acid Sequence; D001430:Bacteriocins / Q000737:chemistry* / Q000302:isolation & purification* / Q000378:metabolism; D001483:Base Sequence; D017124:Conserved Sequence; D005396:Fish Products / Q000032:analysis*; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D041181:Staphylococcus hominis / Q000378:metabolism*; D013785:Thailand
D001430:Bacteriocins; C532383:nukacin KQU-131, Staphylococcus hominis