Data mining tools for genotype-phenotype correlation.
Single Nucleotide Polymorphisms (SNPs) may be the key to diagnosing and treating certain diseases. A preliminary study was conducted at The Ohio State University Medical Center Information Warehouse to correlate such SNPs with a selected group of lab values for cardiology patients. Early results show that data mining tools can be valuable for understanding such correlations, but further refinement of the methodology and data preparation is needed to fully realize such value.
Liu
Jianhua
J
The Information Warehouse, The Ohio State University Medical Center, Columbus, OH 43201, USA.
Buskirk
Jason
J
Santangelo
Jennifer
J
Deiter
Ryan J
RJ
Papp
Audrey
A
Cooke
Glen E
GE
Sadee
Woldgang
W
Kamal
Jyoti
J
D002097:C-Reactive Protein / Q000032:analysis; D002318:Cardiovascular Diseases / Q000097:blood / Q000235:genetics*; D005838:Genotype; D006801:Humans; D016247:Information Storage and Retrieval; D008055:Lipids / Q000097:blood; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide
D008055:Lipids; D002097:C-Reactive Protein