title: Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter.
abstract: Structural delineation and assignment are the fundamental steps in understanding the anatomy of the human brain. The white matter has been structurally defined in the past only at its core regions (deep white matter). However, the most peripheral white matter areas, which are interleaved between the cortex and the deep white matter, have lacked clear anatomical definitions and parcellations. We used axonal fiber alignment information from diffusion tensor imaging (DTI) to delineate the peripheral white matter, and investigated its relationship with the cortex and the deep white matter. Using DTI data from 81 healthy subjects, we identified nine common, blade-like anatomical regions, which were further parcellated into 21 subregions based on the cortical anatomy. Four short association fiber tracts connecting adjacent gyri (U-fibers) were also identified reproducibly among the healthy population. We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies.
authors.affiliation: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Oishi
authors.forename: Karl
authors.initials: K
authors.lastname: Zilles
authors.forename: Katrin
authors.initials: K
authors.lastname: Amunts
authors.forename: Andreia
authors.initials: A
authors.lastname: Faria
authors.forename: Hangyi
authors.initials: H
authors.lastname: Jiang
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Kazi
authors.initials: K
authors.lastname: Akhter
authors.forename: Kegang
authors.initials: K
authors.lastname: Hua
authors.forename: Roger
authors.initials: R
authors.lastname: Woods
authors.forename: Arthur W
authors.initials: AW
authors.lastname: Toga
authors.forename: G Bruce
authors.initials: GB
authors.lastname: Pike
authors.forename: Pedro
authors.initials: P
authors.lastname: Rosa-Neto
authors.forename: Alan
authors.initials: A
authors.lastname: Evans
authors.forename: Jiangyang
authors.initials: J
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Huang
authors.forename: Michael I
authors.initials: MI
authors.lastname: Miller
authors.forename: Peter C M
authors.initials: PC
authors.lastname: van Zijl
authors.forename: John
authors.initials: J
authors.lastname: Mazziotta
authors.forename: Susumu
authors.initials: S
authors.lastname: Mori
mesh_terms: D000293:Adolescent; D000328:Adult; D000716:Anatomy, Artistic; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008488:Medical Illustration; D008875:Middle Aged