title: Asymmetric autocatalytic Mannich reaction in the presence of water and its implication in prebiotic chemistry.
abstract: An enantioselective process in which the chiral Mannich product acts as a catalyst for its own replication was observed to occur under various conditions in the presence of water.
authors.affiliation: Organic Chemistry, Department of Chemistry, Göteborg University, SE-412 96 Göteborg, Sweden. mamou@chem.gu.se
authors.forename: Mohamed
authors.initials: M
authors.lastname: Amedjkouh
authors.forename: Maria
authors.initials: M
authors.lastname: Brandberg
mesh_terms: D002384:Catalysis; D019418:Evolution, Chemical; D008352:Mannich Bases / Q000737:chemistry*; D000069497:Origin of Life; D014867:Water / Q000737:chemistry
chemical_list: D008352:Mannich Bases; D014867:Water