Renal epithelioid angiomyolipoma: a case report and literature review.
BACKGROUND
Renal epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, closely simulating renal cell carcinoma both clinically and histologically. Only a relatively small number of cases of epithelioid angiomyolipoma of the kidney have been reported.


OBJECTIVE
To highlight clinicopathological features of this rare tumour.


METHODS
We report herein a new case of renal epithelioid angiomyolipoma in a 38-year-old male with no stigmata of tuberous sclerosis. The tumour was composed of diffuse sheets of epithelioid cells, small numbers of adipocytes and occasional blood vessels. Immunohistochemically, neoplastic cells were immunoreactive for HMB-45, but negative for cytokeratin. The patient showed no evidence of recurrence or metastatic disease one year after radical nephrectomy.


CONCLUSIONS
Epithelioid angiomyolipoma may be locally aggressive and can metastasise; therefore, long-term post-operative follow-up is mandatory.
Limaïem
F
F
Department of Pathology, Hospital La Rabta, 1007 Bab Saadoun Tunis, Tunisia. fatenlimaiem@yahoo.fr
Mekni
A
A
Chelly
I
I
Nouira
Y
Y
Khadija
B
B
Haouet
S
S
Kchir
N
N
Horchani
A
A
Moncef
Z
Z
D000328:Adult; D018207:Angiomyolipoma / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male