title: Two cases of lupus cystitis with no bladder irritation symptoms.
abstract: Lupus cystitis is a rare manifestation in systemic lupus erythematosus (SLE); it usually occurs in association with gastrointestinal manifestations. We report two cases of lupus cystitis without bladder irritation symptoms. Both cases developed severe abdominal pain, nausea, and diarrhea and showed no bladder irritation symptoms. The diagnosis of lupus cystitis was made by abdominal ultrasonography and bladder biopsy. The patients were treated with intravenous methylprednisolone pulse therapy followed by oral prednisolone. Their symptoms were ameliorated, and hydroureteronephrosis improved. Thus, when a patient with SLE shows gastrointestinal symptoms, further examinations are required to determine whether the patient has lupus cystitis.
authors.affiliation: Department of Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama. kkino@med.kindai.ac.jp
authors.forename: Koji
authors.initials: K
authors.lastname: Kinoshita
authors.forename: Kazuya
authors.initials: K
authors.lastname: Kishimoto
authors.forename: Hideki
authors.initials: H
authors.lastname: Shimazu
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nozaki
authors.forename: Masafumi
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Shinya
authors.initials: S
authors.lastname: Ikoma
authors.forename: Masanori
authors.initials: M
authors.lastname: Funauchi
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001706:Biopsy; D003556:Cystitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008775:Methylprednisolone / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D014463:Ultrasonography; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D011239:Prednisolone; D008775:Methylprednisolone