Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504) isolated from the mangrove plant Aegiceras corniculatum.
Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1) and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indol (3) were isolated, together with ( - )-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.
Li
Li-Ya
LY
State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Ding
Yi
Y
Groth
Ingrid
I
Menzel
Klaus-Dieter
KD
Peschel
Gundela
G
Voigt
Kerstin
K
Deng
Zi-Wei
ZW
Sattler
Isabel
I
Lin
Wen-Han
WH
D000470:Alkaloids / Q000737:chemistry*; D005670:Fusarium / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D029623:Primulaceae / Q000382:microbiology*; D011758:Pyrroles / Q000737:chemistry*
D000470:Alkaloids; D007211:Indoles; D011758:Pyrroles