title: The effects of increasing obesity on outcomes of vascular surgery.
abstract: The aim of this study was to determine whether vascular patients are becoming progressively more obese and whether morbid obesity affects outcomes from vascular surgery. Data for the index vascular procedures of infrainguinal bypass, carotid endarterectomy, and abdominal aortic aneurysm (AAA) repair were collected in a computer database for 1996-2006. Body mass index (BMI) was stratified into <18.5 kg/m2 as underweight, >35 kg/m2 as morbidly obese, and other as control (18.5 < BMI < 35). The data were analyzed with respect to operation duration, length of stay, complication rates, and mortality rates. Results were adjusted for potential confounding variables, including mode of admission, diabetes, cardiac history, renal function, and smoking. A total of 1,317 patients were reviewed, and 1,105 cases were deemed suitable for analysis. The incidence of morbid obesity increased in a linear manner from 1.3% to 9% over the 10-year period. The operation duration was longer for morbidly obese subjects compared with normals. This was only statistically significant for AAA repair category, with a mean operating time of 158.4 +/- 65.5 min for patients with BMI <35 kg/m2 vs. 189.8 +/- 92.2 min for morbidly obese patients (p < 0.014). Infection rates were consistently higher in the morbidly obese group; however, this reached a statistically significant rate among AAA repair cases (43.5% [n = 16] vs. 34.8% [n = 159], p < 0.004). There were no significant differences in other complications, graft failure, length of stay, or mortality. Vascular patients are becoming progressively more obese. Procedures performed on morbidly obese subjects take longer, and these patients have higher rates of infectious complications. This is mainly attributable to AAA. This did not translate into poorer final outcomes in this study, although significant differences might emerge from a larger sample.
authors.affiliation: Vascular Surgery Department, Norfolk and Norwich Vascular Unit, Norfolk and Norwich University Hospital, Norwich, UK. nkh950@yahoo.com
authors.forename: Nader
authors.initials: N
authors.lastname: Khandanpour
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Armon
authors.forename: Rob
authors.initials: R
authors.lastname: Foxall
authors.forename: Felicity J
authors.initials: FJ
authors.lastname: Meyer
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D015992:Body Mass Index; D002340:Carotid Artery Diseases / Q000150:complications / Q000601:surgery; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D015999:Multivariate Analysis; D009767:Obesity, Morbid / Q000150:complications*; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000601:surgery*; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality