title: Preoperative volume prediction in adult live donor liver transplantation: 3-D CT volumetry approach to prevent miscalculations.
abstract: BACKGROUND
  The precise preoperative calculation of functional liver volumes for both donor and recipient is a crucial part of the evaluation process in adult living donor liver transplantation. The purpose of this study was to describe and validate our modus 3-D CT volumetry.
  
  
  METHODS
  Native (unenhanced), arterial, and venous phase CT images from 62 consecutive live liver donors were subjected to 3-D CT liver volume calculations and virtual 3-D liver partitioning. Graft-volume estimates based on our modus 3-D volumetry, which subtracted intrahepatic vascular volume from the "smallest" (native) unenhanced CT phase, were subsequently compared to the intraoperative graft-weights obtained in all 62 cases. Calculated (preoperative) liver-volume-body-weight-ratios and measured (intraoperative) liver-weight-body-weight-ratios of liver grafts were analyzed.
  
  
  RESULTS
  Preoperative calculations of graft-volume according to our modus 3-D CT volumetry did not yield statistically significant over- or under-estimations when compared to the intraoperative findings independent of their age or gender.
  
  
  CONCLUSIONS
  Our modus 3-D volumetry, when based on the "smallest" (native) unenhanced CT phase, accurately accounted for intrahepatic vascular volumes and offered a precise virtual model of individualized operative conditions for each potential live liver donor.
authors.affiliation: Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Radtke
authors.forename: G C
authors.initials: GC
authors.lastname: Sotiropoulos
authors.forename: S
authors.initials: S
authors.lastname: Nadalin
authors.forename: E P
authors.initials: EP
authors.lastname: Molmenti
authors.forename: T
authors.initials: T
authors.lastname: Schroeder
authors.forename: F H
authors.initials: FH
authors.lastname: Saner
authors.forename: G
authors.initials: G
authors.lastname: Sgourakis
authors.forename: V R
authors.initials: VR
authors.lastname: Cicinnati
authors.forename: C
authors.initials: C
authors.lastname: Valentin-Gamazo
authors.forename: C E
authors.initials: CE
authors.lastname: Broelsch
authors.forename: M
authors.initials: M
authors.lastname: Malago
authors.forename: Hauke
authors.initials: H
authors.lastname: Lang
mesh_terms: D000328:Adult; D000465:Algorithms; D001706:Biopsy; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging* / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D020858:Tissue and Organ Harvesting / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography