Structural evidence that scytalidolisin (formerly scytalidopepsin A) is a serine-carboxyl peptidase of the sedolisin family.
Scytalidopepsin A, a pepstatin-insensitive acid endopeptidase from the fungus Scytalidium lignicolum was found to be a member of the sedolisin family of serine-carboxyl peptidases through analyses of the amino acid sequences of peptides derived from the reduced, pyridylethylated enzyme by enzymatic digestion. Hence it should be renamed scytalidolisin (or Scytalidium sedolisin).
Takahashi
Kenji
K
Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Japan. kenjitak@ls.toyaku.ac.jp
Oda
Kohei
K
D000595:Amino Acid Sequence; D001203:Ascomycota / Q000201:enzymology; D002268:Carboxypeptidases / Q000737:chemistry* / Q000145:classification / Q000378:metabolism*; D017124:Conserved Sequence; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D012697:Serine Endopeptidases / Q000737:chemistry* / Q000145:classification / Q000378:metabolism*
D002268:Carboxypeptidases; D012697:Serine Endopeptidases; C479198:sedolisin