title: A testing approach based on tiny doses still awaits big results.
authors.forename: Amy
authors.initials: A
authors.lastname: Coombs
mesh_terms: D000818:Animals; D001682:Biological Availability; D001709:Biotechnology / Q000191:economics / Q000639:trends*; D004195:Disease Models, Animal; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004345:Drug Industry / Q000191:economics / Q000639:trends*; D006801:Humans; D012109:Research Support as Topic; D014481:United States; D014486:United States Food and Drug Administration