title: Structural changes of poly-L-lysine in solution and lyophilized form.
abstract: Two structural changes of poly-L-lysine have been studied by various spectroscopic techniques; one is a structural change of a random coil sample in solution to a mixture of alpha-helix and beta-sheet during rapid freezing in the lyophilizing process, and the other is a pressure-induced structural change from an alpha-helix to a beta-sheet structure for a lyophilized sample.
authors.affiliation: Graduate School of Science and Technology, Kobe University, Nada, Kobe, Japan.
authors.forename: Ohki
authors.initials: O
authors.lastname: Kambara
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tamura
authors.forename: Akira
authors.initials: A
authors.lastname: Naito
authors.forename: Keisuke
authors.initials: K
authors.lastname: Tominaga
mesh_terms: D005612:Freeze Drying; D009682:Magnetic Resonance Spectroscopy; D011107:Polylysine / Q000737:chemistry*; D011487:Protein Conformation; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D012996:Solutions; D011107:Polylysine