title: [A cause of intracerebral calcifications that should be known: pseudohypoparathyroidism Ib].
abstract: In children, pseudohypoparathyroidism (PHP) is a rare but classical cause of basal ganglia calcifications. It is caused by resistance to parathormone (PTH). Hypocalcemia, which may be symptomatic, is its main feature. We report the case of a 13-year-old boy, affected by type Ib PHP revealed by hypocalcemia and seizures, with basal ganglia calcifications on the CT scan. We describe the characteristics of the 2 main types of PHP and emphasize the search for this disease when basal ganglia calcifications are discovered, even fortuitously, on a cerebral CT scan.
authors.affiliation: Service de pédiatrie, hôpital l'Archet II, route Saint-Antoine-de-Ginestière, 06200 Nice, France. pfaissolle@free.fr
authors.forename: P
authors.initials: P
authors.lastname: Faissolle
authors.forename: K
authors.initials: K
authors.lastname: Wagner-Mahler
authors.forename: J-C
authors.initials: JC
authors.lastname: Mas
authors.forename: M
authors.initials: M
authors.lastname: Moreigne
authors.forename: A
authors.initials: A
authors.lastname: Khalfi
authors.forename: V
authors.initials: V
authors.lastname: Léonetti
authors.forename: M
authors.initials: M
authors.lastname: Silvy
authors.forename: A
authors.initials: A
authors.lastname: Barlier
authors.forename: H
authors.initials: H
authors.lastname: Giudicelli
mesh_terms: D000293:Adolescent; D001480:Basal Ganglia Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D008297:Male; D011547:Pseudohypoparathyroidism / Q000175:diagnosis*; D011859:Radiography; D012640:Seizures / Q000209:etiology