Henoch-Schönlein purpura and thrombocytopenia after planned antiretroviral treatment interruption in a Thai girl with HIV infection.
A handful of Henoch-Schönlein purpura (HSP) cases have been reported in HIV-infected adult patients. We report herein the case of an 11-year-old Thai girl with HIV infection, who developed severe abdominal pain and palpable purpura consistent with HSP, 3 months after planned antiretroviral treatment interruption (PTI). One month later she developed thrombocytopenia. It is possible that an HIV effect on vascular endothelium or PTI-associated immune activation contributed to HSP and thrombocytopenia.
Bunupuradah
Torsak
T
The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center, Bangkok, Thailand. torsak.b@hivnat.org
Puthanakit
Thanyawee
T
Pancharoen
Chitsanu
C
Butterworth
Oratai
O
Phanuphak
Praphan
P
Ananworanich
Jintanat
J
D019380:Anti-HIV Agents / Q000008:administration & dosage; D002648:Child; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy* / Q000821:virology; D015497:HIV-1; D006801:Humans; D011695:IgA Vasculitis / Q000209:etiology*; D018894:Reverse Transcriptase Inhibitors / Q000008:administration & dosage; D013785:Thailand; D013921:Thrombocytopenia / Q000209:etiology*
D019380:Anti-HIV Agents; D018894:Reverse Transcriptase Inhibitors