Fluorination reactions in microreactors.
The DAST-mediated conversion of a range of alcohols to the corresponding fluorides in a microstructured device is described. This safe, practical fluorination method will facilitate reactions currently challenging on large scale.
Gustafsson
Tomas
T
Swiss Federal Institute of Technology (ETH) Zurich, Laboratorium für Organische Chemie, HCI F 315, CH-8093 Zurich, Switzerland.
Gilmour
Ryan
R
Seeberger
Peter H
PH
D000438:Alcohols / Q000737:chemistry*; D004048:Diethylamines / Q000737:chemistry; D005459:Fluorides / Q000138:chemical synthesis*; D005461:Fluorine / Q000737:chemistry; D008832:Microchemistry / Q000379:methods*
D000438:Alcohols; D004048:Diethylamines; D005461:Fluorine; C040394:diethylaminosulfur trifluoride; D005459:Fluorides