title: Ovine toxoplasmosis: transmission, clinical outcome and control.
abstract: Toxoplasma gondii is a significant cause of abortion in sheep. Infection is picked up from the environment and if initiated during pregnancy may cause fetal mortality. Infected sheep remain persistently infected with tissue cysts in brain and muscle (meat), and are also immune and would not be expected to abort again. The live tachyzoite vaccine (Toxovax) protects against abortion and this allows the suggestion that it may also reduce or prevent tissue cyst development in muscle. If this were so it raises the question of whether the vaccine could be used to make meat safer for human consumption.
authors.affiliation: Moredun Research Institute, Edinburgh, Scotland, UK. david.buxton@moredun.ac.uk
authors.forename: D
authors.initials: D
authors.lastname: Buxton
authors.forename: S W
authors.initials: SW
authors.lastname: Maley
authors.forename: S E
authors.initials: SE
authors.lastname: Wright
authors.forename: S
authors.initials: S
authors.lastname: Rodger
authors.forename: P
authors.initials: P
authors.lastname: Bartley
authors.forename: E A
authors.initials: EA
authors.lastname: Innes
mesh_terms: D000034:Abortion, Veterinary / Q000453:epidemiology / Q000209:etiology / Q000469:parasitology / Q000517:prevention & control; D000821:Animal Feed / Q000469:parasitology; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002415:Cats; D003667:Decoquinate / Q000627:therapeutic use; D005260:Female; D005506:Food Contamination; D018445:Infectious Disease Transmission, Vertical; D018512:Parasitemia / Q000453:epidemiology / Q000469:parasitology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary; D016052:Protozoan Vaccines; D012756:Sheep; D012757:Sheep Diseases / Q000151:congenital / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D013552:Swine / Q000469:parasitology; D014124:Toxoplasmosis, Animal / Q000151:congenital / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; D016052:Protozoan Vaccines; C532473:tovomax; D003667:Decoquinate