Genomic analysis and geographic visualization of H5N1 and SARS-CoV.
Emerging infectious diseases and organisms present critical issues of national security public health, and economic welfare. We still understand little about the zoonotic potential of many viruses. To this end, we are developing novel database tools to manage comparative genomic datasets. These tools add value because they allow us to summarize the direction, frequency and order of genomic changes. We will perform numerous real world tests with our tools with both Avian Influenza and Coronaviruses.
Hill
Andrew W
AW
Department of Ecology and Evolutionary Biology and Museum of Natural History,University of Colorado, Boulder CO 80309, USA.
Alexandrov
Boyan
B
Guralnick
Robert P
RP
Janies
Daniel
D
D000818:Animals; D001717:Birds; D021821:Communicable Diseases, Emerging / Q000453:epidemiology; D004196:Disease Outbreaks; D016679:Genome, Viral; D014943:Global Health; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics; D009976:Orthomyxoviridae Infections / Q000453:epidemiology* / Q000821:virology; D011159:Population Surveillance / Q000379:methods; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology*