title: Cell survival and chromosomal aberrations in CHO-K1 cells irradiated by carbon ions.
abstract: Chinese hamster ovary CHO-K1 cells were exposed to high LET (12)C-beam (LET: 830 keV/microm) in the dose range of 0-6 Gy and to (60)Co irradiation and the RBE value was obtained. Effects of (12)C-beam exposure on cell survival and chromosomal aberrations were calculated. The chromosomal aberration data were fitted with linear equation. The distribution of aberration in cells was examined with a standard u-test and used to evaluate the data according to Poisson probabilities. The variance to the mean ratio sigma(2)/Y and the dispersion index (u) were determined. Overdispersion was significant (p<0.05) when the value of u exceeded 1.96.
authors.affiliation: Institute of Physics, Swietokrzyska Academy, ul. Swietokrzyska 15, 25-406 Kielce, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Czub
authors.forename: D
authors.initials: D
authors.lastname: Banaś
authors.forename: A
authors.initials: A
authors.lastname: Błaszczyk
authors.forename: J
authors.initials: J
authors.lastname: Braziewicz
authors.forename: I
authors.initials: I
authors.lastname: Buraczewska
authors.forename: J
authors.initials: J
authors.lastname: Choiński
authors.forename: U
authors.initials: U
authors.lastname: Górak
authors.forename: M
authors.initials: M
authors.lastname: Jaskóła
authors.forename: A
authors.initials: A
authors.lastname: Korman
authors.forename: A
authors.initials: A
authors.lastname: Lankoff
authors.forename: H
authors.initials: H
authors.lastname: Lisowska
authors.forename: A
authors.initials: A
authors.lastname: Łukaszek
authors.forename: Z
authors.initials: Z
authors.lastname: Szefliński
authors.forename: A
authors.initials: A
authors.lastname: Wójcik
mesh_terms: D000818:Animals; D016466:CHO Cells / Q000528:radiation effects; D002250:Carbon Radioisotopes; D002470:Cell Survival / Q000528:radiation effects*; D002869:Chromosome Aberrations / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D007477:Ions; D016012:Poisson Distribution; D011827:Radiation
chemical_list: D002250:Carbon Radioisotopes; D007477:Ions