title: Direct invasion to the colon by hepatocellular carcinoma: report of two cases.
abstract: Although hepatocellular carcinoma (HCC) is a common tumor, direct invasion of the gastrointestinal tract by HCC is uncommon. Recently, we encountered two cases of HCC with direct invasion to the colon. The first patient was a 79-year-old man who underwent transarterial chemo-embolization (TACE) for HCC 1.5 years prior to admission to our hospital. Computed tomography (CT) showed a 7.5-cm liver tumor directly invading the transverse colon. Partial resection of the liver and transverse colon was performed. The patient survived 6 mo after surgery, but died of recurrent HCC. The second patient was a 69-year-old man who underwent TACE and ablation for HCC 2 years and 7 months prior to being admitted to our hospital for melena and abdominal distension. CT revealed a 6-cm liver tumor with direct invasion to the colon. The patient underwent partial resection of the liver and right hemicolectomy. The patient recovered from the surgery. But, unfortunately, he died of liver failure due to liver cirrhosis one month later. Although the prognosis of HCC that has invaded the colon is generally poor due to the advanced stage of the disease, surgical resection may be a favorable treatment option in patients with a good general condition.
authors.affiliation: Department of Surgery I, Oita University Faculty of Medicine, Yuhu, Oita 879-5593, Japan. teij01@ray.ocn.ne.jp
authors.forename: Teijiro
authors.initials: T
authors.lastname: Hirashita
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ohta
authors.forename: Kentaro
authors.initials: K
authors.lastname: Iwaki
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kai
authors.forename: Kohei
authors.initials: K
authors.lastname: Shibata
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sasaki
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Nakashima
authors.forename: Seigo
authors.initials: S
authors.lastname: Kitano
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D009361:Neoplasm Invasiveness; D011379:Prognosis