title: De novo autoimmune hepatitis following liver transplantation: a case report.
abstract: De novo autoimmune hepatitis (AIH), a rare disorder first described in 1998, appears in patients with liver transplants due to autoimmune and nonautoimmune etiologies. De novo AIH occurs in 2.5% to 3.4% of allografts; children seem to have a predilection for this syndrome. We have present herein a case of a liver allograft recipient who developed chronic hepatitis associated with autoimmune features outlining the clinical course, liver histology, and response to treatment.
authors.affiliation: Department of Surgery, Transplant Unit, University of L'Aquila, San Salvatore Hospital, L'Aquila, Italy. dcp.doc@libero.it
authors.forename: P
authors.initials: P
authors.lastname: Di Cocco
authors.forename: A
authors.initials: A
authors.lastname: Barletta
authors.forename: K
authors.initials: K
authors.lastname: Clemente
authors.forename: M
authors.initials: M
authors.lastname: D'Angelo
authors.forename: S
authors.initials: S
authors.lastname: Greco
authors.forename: C
authors.initials: C
authors.lastname: Mazzotta
authors.forename: G
authors.initials: G
authors.lastname: Orlando
authors.forename: V
authors.initials: V
authors.lastname: Rizza
authors.forename: A
authors.initials: A
authors.lastname: Famulari
authors.forename: A
authors.initials: A
authors.lastname: Grimaldi
authors.forename: F
authors.initials: F
authors.lastname: Pisani
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000601:surgery; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D019693:Hepatitis, Autoimmune / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000601:surgery*; D017093:Liver Failure / Q000209:etiology / Q000601:surgery; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase