title: An interpretative phenomenological analysis of adaptation to recurrent venous thrombosis and heritable thrombophilia: the importance of multi-causal models and perceptions of primary and secondary control.
abstract: Venous thromboembolic disease (VTE) is a serious, life-threatening condition and a major cause of mortality and morbidity. Heritable thrombophilia increases risk of recurrent VTE. The present study employed Interpretative Phenomenological Analysis (IPA) to explore adaptation to recurrent VTE and heritable thrombophilia in six female patients. Three main themes were identified focusing on: (1) patients' multi-causal models of VTE and the maintenance of; (2) primary control; and (3) secondary control as facilitators of adjustment. Overall, genetic testing following recurrent VTE did not have a negative impact on patients. One area of concern, however, related to passing on the susceptibility to children.
authors.affiliation: Psychology, Sheffield Hallam University, Sheffield Haemophilia and Thrombosis Centre, Sheffield, UK. t.j.moore@shu.ac.uk
authors.forename: Tria
authors.initials: T
authors.lastname: Moore
authors.forename: Paul
authors.initials: P
authors.lastname: Norman
authors.forename: Peter R
authors.initials: PR
authors.lastname: Harris
authors.forename: Michael
authors.initials: M
authors.lastname: Makris
mesh_terms: D000328:Adult; D000368:Aged; D001291:Attitude of Health Personnel; D001364:Awareness; D003710:Demography; D005260:Female; D006801:Humans; D008875:Middle Aged; D011320:Primary Health Care / Q000379:methods*; D012008:Recurrence; D011795:Surveys and Questionnaires; D019851:Thrombophilia / Q000235:genetics* / Q000628:therapy*; D020246:Venous Thrombosis / Q000628:therapy*