title: Food allergy mediated by IgG antibodies associated with migraine in adults.
abstract: BACKGROUND
  Migraine occurs with a high prevalence of 18 per cent. Management requires a tailored regimen of pharmacological and other measures based on individual clinical history. In some patients, allergen-specific IgG has been suspected to be involved in their mechanism, however, serological methods to investigate such possibility, are seldomly used.
  
  
  OBJECTIVE
  The aim of this study was to investigate allergen-specific IgG in serum of patients with migraine refractory to traditional treatment.
  
  
  METHODS
  Serum antibodies to specific 108 food allergens were measured by enzyme immunoassay from 56 patients with migraine and a control group without migraine.
  
  
  RESULTS
  In addition to statistical significant differences in the number of positives for IgG food allergens between patients with migraine and a controlled group, elimination diets successfully control the migraine without the need of medications.
  
  
  CONCLUSIONS
  According to the results obtained, serum IgG antibodies to common food should be investigated in patients with migraine.
authors.affiliation: Centro de Inmunología y Alergias, Querétaro, Querétaro, México.
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Arroyave Hernández
authors.forename: Mauro
authors.initials: M
authors.lastname: Echavarría Pinto
authors.forename: Mauro
authors.initials: M
authors.lastname: Echevarría Pinto
authors.forename: Hebert Luis
authors.initials: HL
authors.lastname: Hernández Montiel
mesh_terms: D000328:Adult; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications* / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence
chemical_list: D007074:Immunoglobulin G