A cross-sectional study on aqueous humour lactate dehydrogenase level in retinoblastoma.
Lactate dehydrogenase enzyme is a non-specific marker found raised in different body fluids in various pathological conditions. This cross-sectional study was done in a medical college of Kolkata, India to find out lactate dehydrogenase level of aqueous humour in retinoblastoma cases. Aqueous humour lactate dehydrogenase level from 21 histology proved retinoblastoma cases and 21 controls was estimated and compared. Range of lactate dehydrogenase levels in retinoblastoma cases were 863-4819 IU/l; mean being 3396.9 IU/l; and in controls range was 48-146 IU/l; mean being 90.6 IU/l; 76.19% of retinoblastoma cases had value over 3000 IU/l. None of the controls had value above 150 IU/l. The difference between lactate dehydrogenase values of cases and controls was significant (p<0.001).
Mukhopadhyay
Subhalakshmi
S
Department of Pathology, Midnapore Medical College and Hospital, Paschim Mednipur.
Ghosh
Sambuddha
S
Biswas
Pradyot Narayan
PN
Dutta
Subir Kumar
SK
Chattopadhyay
Debnath
D
D001082:Aqueous Humor / Q000201:enzymology*; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D011379:Prognosis; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000201:enzymology*; D012175:Retinoblastoma / Q000175:diagnosis / Q000201:enzymology*; D012720:Severity of Illness Index
D014408:Biomarkers, Tumor; D007770:L-Lactate Dehydrogenase