title: Variable association between Chlamydophila psittaci infection and ocular adnexal lymphomas: methodological biases or true geographical variations?
abstract: Since the first publication in 2004, a large number of reports have raised the question of an association between ocular adnexal lymphoma and Chlamydia psittaci. The results of this scientific debate, however, remain controversial. The primary objective of this paper was therefore to raise important questions concerning the interpretation of the different and heterogeneous data on the association between Chlamydophila psittaci and ocular adnexal lymphoma, namely the impact of the methodology used and the epidemiological variability of seroprevalence of C. psittaci antibodies. This paper also provides some methodological suggestions for future studies in the field of chlamydia-lymphoma associations.
authors.affiliation: Department of Clinical Hematology, Institut Curie, Paris, France. didier.decaudin@curie.net
authors.forename: Didier
authors.initials: D
authors.lastname: Decaudin
authors.forename: Riccardo
authors.initials: R
authors.lastname: Dolcetti
authors.forename: Patricia
authors.initials: P
authors.lastname: de Cremoux
authors.forename: Maurilio
authors.initials: M
authors.lastname: Ponzoni
authors.forename: Anne
authors.initials: A
authors.lastname: Vincent-Salomon
authors.forename: Claudio
authors.initials: C
authors.lastname: Doglioni
authors.forename: Rémi
authors.initials: R
authors.lastname: Dendale
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Escande
authors.forename: Livia
authors.initials: L
authors.lastname: Lumbroso-Le Rouic
authors.forename: Andrés J M
authors.initials: AJ
authors.lastname: Ferreri
mesh_terms: D015982:Bias; D002691:Chlamydophila psittaci; D005134:Eye Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D005843:Geography; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000453:epidemiology*; D009956:Psittacosis / Q000175:diagnosis / Q000453:epidemiology*; D016036:Seroepidemiologic Studies