[A case of bird related hypersensitivity pneumonitis had a progressive course].
A 50-year-old woman was admitted due to productive cough continuing for 3 years. A chest computed tomography showed appearance of nonspecific interstitial pneumonia (NSIP). Thoracoscopic lung biopsy specimens showed mainly a pattern of NSIP with multinucleated cells and cholesterol clefts. She was not a bird fancier, but had indirect exposure to birds in her living environment, and had been using feather-filled duvets for a long time. We established a diagnosis of bird-related hypersensitivity pneumonitis based on antibodies in serum positive to pigeon dropping extracts. She was treated by coadministration of corticosteroids and immunosuppressants, and avoidance of bird-related antigens, but had a progressive course and died of respiratory failure.
Kohno
Ayumi
A
Department of Respiratory Medicine, Tokyo Metropolitan Hiroo Hospital.
Enomoto
Tatsuji
T
Kaneko
Kazuyo
K
Saitoh
Hitoshi
H
Narato
Ritsuko
R
Yomota
Makiko
M
Tanaka
Michio
M
Takemura
Tamiko
T
Nakamura
Seiichi
S
D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000628:therapy*; D000818:Animals; D001716:Bird Fancier's Lung / Q000175:diagnosis; D001717:Birds / Q000276:immunology; D005260:Female; D006801:Humans; D008875:Middle Aged