Controlling the formation of 1 out of 64 stereoisomers using organocatalysis.
The formation of 1 out of 64 stereoisomers, i.e. controlling the creation of 6 stereocenters, of important optically active bicyclo[3.3.1]non-2-ene compounds, has been achieved using organocatalysis; the reaction proceeds with excellent stereocontrol and can be carried out with the generation of enantiopure products using chromatography-free procedures.
Bertelsen
Søren
S
Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark.
Johansen
Rasmus L
RL
Jørgensen
Karl Anker
KA
D000447:Aldehydes / Q000737:chemistry; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis*; D002384:Catalysis; D008958:Models, Molecular; D013237:Stereoisomerism
D000447:Aldehydes; D001643:Bridged Bicyclo Compounds