title: Long-term outcome of parenthood project during in vitro fertilization and after discontinuation of unsuccessful in vitro fertilization.
abstract: OBJECTIVE
  To explore the long-term outcome of patients who began IVF treatment by considering not only treatment outcome in the center but also the parenthood project outcome after discontinuation of unsuccessful IVF.
  
  
  METHODS
  Retrospective cohort follow-up study.
  
  
  METHODS
  Two French IVF centers.
  
  
  METHODS
  Seven hundred twenty-four patients who began IVF treatment in 1998.
  
  
  METHODS
  Postal and phone contacts with unsuccessful IVF patients.
  
  
  METHODS
  Long-term outcome of parenthood project.
  
  
  RESULTS
  Of the 724 patients, a minimum of 53% and a maximum of 81% finally succeeded in their parenthood project during or after IVF treatment (depending on the hypotheses that the 204 patients not contacted either failed or succeeded in their parenthood project). An intermediate hypothesis gave an estimation of 66% of patients finally succeeding in having a child (40% during IVF treatment in the center and 26% after). Achievement of the parenthood project after IVF discontinuation was due mainly to adoption of a child (46%) or a birth following a spontaneous pregnancy (42%).
  
  
  CONCLUSIONS
  Unsuccessful patients should not lose hope, because nearly half may subsequently succeed in having a child.
authors.affiliation: INSERM Unit 822, 82 rue du General Leclerc, Le Kremlin-Bicêtre Cedex, France. roche@ined.fr
authors.forename: Elise
authors.initials: E
authors.lastname: de La Rochebrochard
authors.forename: Céline
authors.initials: C
authors.lastname: Quelen
authors.forename: Rusudan
authors.initials: R
authors.lastname: Peikrishvili
authors.forename: Juliette
authors.initials: J
authors.lastname: Guibert
authors.forename: Jean
authors.initials: J
authors.lastname: Bouyer
mesh_terms: D000300:Adoption; D000328:Adult; D015331:Cohort Studies; D004624:Embryo Transfer / Q000379:methods; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods* / Q000523:psychology / Q000706:statistics & numerical data*; D005602:France; D006801:Humans; D007398:Interpersonal Relations; D007407:Interviews as Topic; D008297:Male; D010290:Parents / Q000523:psychology*; D011247:Pregnancy; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013689:Telephone; D017211:Treatment Failure; D016896:Treatment Outcome