Colon and rectal cancer after renal transplantation.
Increased cancer risk after renal transplantation is believed to be a consequence of continuous immunosuppression. However, the risk of colorectal cancer (CRC) after renal transplantation is controversial and has received limited study. Accumulating evidence suggests that colon and rectal cancers have different characteristics in the post-renal transplant patient (PRTP) and should be evaluated separately in transplant registries. This article reviews the current literature evaluating CRC diagnosed in PRTPs, focusing on clinical characteristics and treatment outcomes.
Kan
Manstein
M
Department of Surgery, St Paul's Hospital, University of British Columbia, C303-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada. mansteinkan@hotmail.com
Gill
John S
JS
Wiseman
Sam M
SM
D002170:Canada / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation; D008297:Male; D012004:Rectal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D012307:Risk Factors; D014481:United States / Q000453:epidemiology