Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate.
Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.
Cianfoni
A
A
Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, Department of Bio-images and Radiological Sciences, Rome, Italy.
Wintermark
M
M
Piludu
F
F
D'Alessandris
Q G
QG
Lauriola
L
L
Visocchi
M
M
Colosimo
C
C
D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged
D003287:Contrast Media