Identification of transmembrane region and orientation of aquaglyceroporin of Plasmodium falciparum.
Aquaglyceroporin is a subclass of aquaporin water channels. This protein is also a focused potential drug target for falciparum malaria. However, the knowledge about the structure of this protein is limited. In this communication, the author performed a study to determine the transmembrane region and orientation of aquaglyceroporin of Plasmodium falciparum . According to this study, six transmembrane regions of aquaglyceroporin of P. falciparum can be identified. These regions can be the focused target for future drug development.
Wiwanitkit
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Department of Clinical Laboratory Medicine, Faculty of Medicine, Wiwanitkit House, Bangkhae, Bangkok 10160, Thailand. wviroj@yahoo.com
D000595:Amino Acid Sequence; D000818:Animals; D051397:Aquaglyceroporins / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000235:genetics*; D017433:Protein Structure, Secondary
D051397:Aquaglyceroporins