A novel bla(CTX-M-14) gene-harboring complex class 1 integron with an In4-like backbone structure from a clinical isolate of Escherichia coli.
Escherichia coli BDE0502 contained 3 beta-lactamase genes including bla(DHA-1), bla(SHV-12), and bla(CTX-M-14). The bla(CTX-M-14) gene was found on a complex class 1 integron with an In4-like backbone structure. The bla(CTX-M-14) gene was proceeded by a partial copy of ISEcp1 in addition to the complete copy of ISCR1 element.
Bae
Il Kwon
IK
Research Institute for Antimicrobial Resistance, Kosin University College of Medicine, Busan 602-030, South Korea.
Lee
Yong Hwan
YH
Jeong
Ho Joong
HJ
Hong
Seong Geun
SG
Lee
Sang Hee
SH
Jeong
Seok Hoon
SH
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000201:enzymology / Q000382:microbiology*; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D032023:Integrons; D007723:Korea; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics*; D047090:beta-Lactams / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases