Glassy cell carcinoma of the urethra.
Glassy cell carcinoma is a poorly differentiated form of adenosquamous carcinoma that has never been reported in the urinary tract. We present the first case of primary glassy cell carcinoma of the urethra in a 48-year-old woman. She presented with a newly developed bulky mass protruding from her urethra. A biopsy of this mass revealed sheets of large polygonal cells with a "ground-glass" cytoplasm among a heavy inflammatory infiltrate, establishing the diagnosis of glassy cell carcinoma of the urethra. Treatment of her tumor included a combined surgical and chemotherapeutic approach.
Weissbart
Steven J
SJ
Department of Urology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Bianco
Fernando J
FJ
Sotelo
Tiffany
T
Atalla
Mohamed A
MA
Sesterhenn
Isabell A
IA
Jarrett
Thomas W
TW
D018196:Carcinoma, Adenosquamous / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014523:Urethral Neoplasms / Q000473:pathology*