title: Right ventricular myocardial velocities and timing estimate pulmonary artery systolic pressure.
abstract: BACKGROUND
  Non-invasive estimation of pulmonary artery systolic pressure (PASP) is important for identifying and following up patients. We aimed at revisiting the accuracy of various right ventricular (RV) Doppler echocardiographic measurements of PASP.
  
  
  METHODS
  Twenty-eight patients were studied with simultaneous right heart catheterization (RHC), conventional and tissue Doppler echocardiography (TDE). We measured RV-right atrial (RA) peak pressure drop, RV spectral filling and myocardial velocities and timings.
  
  
  RESULTS
  RV-RA peak pressure drop (r=0.89, p<0.001) strongly correlated with PASP. Both RV spectral and myocardial measurements of isovolumic relaxation time (IVRT) modestly correlated with PASP (r=0.63, p<0.01 and <0.001). Time interval measurements missed 6 and 9 cases with normal PASP by using proposed cut off values. Combining myocardial IVRT and isovolumic contraction velocity (IVCV) in a formula, predicted PASP in all but 3 of our patients. In addition, TDE measurements were obtainable in all cases compared to RV-RA gradient which were measurable in only 64% of patients.
  
  
  CONCLUSIONS
  RV-RA peak pressure drop is the most accurate non-invasive method for assessing PASP. Combining myocardial IVCV and IVRT can be used accurately in estimating PASP being more feasible than RV-RA drop. Such additional measurement might be important in patients follow-up when RV-RA gradient is difficult to obtain.
authors.affiliation: Department of Clinical Physiology, Heart Centre, Umeå University Hospital, Umeå, Sweden. per.lindqvist@medicin.umu.se
authors.forename: Per
authors.initials: P
authors.lastname: Lindqvist
authors.forename: Michael Y
authors.initials: MY
authors.lastname: Henein
authors.forename: Gerhard
authors.initials: G
authors.lastname: Wikström
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D015150:Echocardiography, Doppler / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D013997:Time Factors; D016278:Ventricular Function, Right / Q000502:physiology*; D055815:Young Adult