title: Peptide mass fingerprinting using isotopically encoded photo-crosslinking amino acids.
abstract: When isotopically labelled photo-crosslinking amino acids are site-specifically incorporated into proteins, in combination with the corresponding non-labeled analogue, cross-linked tryptic peptides are easily identified in mass spectra via characteristic "doublet" patterns.
authors.affiliation: Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
authors.forename: Bryan J
authors.initials: BJ
authors.lastname: Wilkins
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Daggett
authors.forename: T Ashton
authors.initials: TA
authors.lastname: Cropp
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000378:metabolism; D003432:Cross-Linking Reagents / Q000737:chemistry; D007553:Isotope Labeling; D013058:Mass Spectrometry; D008958:Models, Molecular; D008970:Molecular Weight; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism; D010449:Peptide Mapping / Q000379:methods*
chemical_list: D000596:Amino Acids; D003432:Cross-Linking Reagents; D010446:Peptide Fragments