title: Impaired spermatogenesis by testicular sarcoidosis.
abstract: Testicular involvement by sarcoidosis is a rare condition. A 23-year-old Japanese man had asymptomatic bilateral testicular lesions, which were detected by gallium scintigram, together with lesions located bilaterally in the uvea, lungs and hilar, and mediastinal lymph nodes and unilateral supraclavicular lymph nodes. Semen analysis demonstrated severely impaired spermatogenesis. Treatment with corticosteroid dramatically improved these lesions and restored spermatogenesis. This case report suggests that testicular sarcoidosis may cause male infertility.
authors.affiliation: Department of Respirology B2, Graduate School of Medicine, Chiba University, Chiba, Japan. takiguchi@faculty.chiba-u.jp
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takiguchi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Matsuno
authors.forename: Katsushi
authors.initials: K
authors.lastname: Kurosu
authors.forename: Osamu
authors.initials: O
authors.lastname: Okada
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Sho
authors.initials: S
authors.lastname: Ohta
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Ichikawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kuriyama
mesh_terms: D000284:Administration, Oral; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012507:Sarcoidosis / Q000188:drug therapy / Q000473:pathology*; D055101:Semen Analysis; D013091:Spermatogenesis / Q000187:drug effects / Q000502:physiology*; D013094:Spermatozoa / Q000473:pathology*; D013733:Testicular Diseases / Q000188:drug therapy / Q000473:pathology*; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone