Cancer and stem cell biology: how tightly intertwined?
Ever since the discovery of cancer stem cells in leukemia and, more recently, in solid tumors, enormous attention has been paid to the apparent stem cell nature of cancer. These concepts were the focus of the "Stem Cells and Cancer" symposium held recently at the University of California, San Francisco, and the inspiration for this overview of current research and important questions emerging in this area.
Kim
Carla F
CF
Stem Cell Program, Children's Hospital Boston, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. carla.kim@childrens.harvard.edu
Dirks
Peter B
PB
D000818:Animals; D004358:Drug Therapy; D033041:Embryo Research; D006801:Humans; D009369:Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology; D015398:Signal Transduction