title: Number of teeth and mortality risk in the Baltimore Longitudinal Study of Aging.
abstract: BACKGROUND
  Findings from several studies suggested an association between oral health and several health outcomes including cardiovascular disease, aspiration pneumonia, malnutrition, poor quality of life, and mortality. Using data from the Baltimore Longitudinal Study of Aging (BLSA), we tested the hypothesis that number of teeth is indicative of mortality risk independent of other confounders.
  
  
  METHODS
  Dentists conducted a standardized oral examination that included tooth count, tooth with coronal and cervical caries count, and gingival and periodontal index. Blood tests used in the analysis included fasting glucose, oral glucose tolerance test, serum low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, triglycerides, and white blood cell counts. Physical activity, skin fold thickness, body mass index and chronic diseases were also evaluated.
  
  
  RESULTS
  Of the 500 BLSA participants evaluated, 198 died an average of 130 (+/-75) months postdental evaluation, and 302 survivors were followed for a mean of 185 (+/-90) months. Based on multivariate Cox regression models, being edentulous or having than 20 teeth was independently associated with mortality.
  
  
  CONCLUSIONS
  The results of this study support the notion that number of teeth is a significant and independent risk indicator for early mortality. These findings suggest that the improvement of oral health may have a positive impact on general health and may delay mortality.
authors.affiliation: Community Oral Health Department, Dental School, UFRGS, R Ramiro Barcelos, 2492 Porto Alegre, RS, Brazil. dalvapadilha@via-rs.net
authors.forename: Dalva Maria Pereira
authors.initials: DM
authors.lastname: Padilha
authors.forename: Juliana Balbinot
authors.initials: JB
authors.lastname: Hilgert
authors.forename: Fernando Neves
authors.initials: FN
authors.lastname: Hugo
authors.forename: Angelo José Gonçalves
authors.initials: AJ
authors.lastname: Bós
authors.forename: Luigi
authors.initials: L
authors.lastname: Ferrucci
mesh_terms: D000368:Aged; D004245:DMF Index; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009026:Mortality; D009910:Oral Hygiene; D010512:Periodontal Index; D016016:Proportional Hazards Models; D012307:Risk Factors; D016388:Tooth Loss