Design and synthesis of medium-ring lactam libraries inspired by octalactin a. A convergent-divergent approach.
Brown
Neil
N
Department of Chemistry, University of Missouri, 205 Spencer Chemical Laboratories, 5100 Rockhill Road, Kansas City, Missouri 64110, USA.
Gao
Ge
G
Minatoya
Machiko
M
Xie
Baohan
B
Vandervelde
David
D
Lushington
Gerald H
GH
Perchellet
Jean-Pierre H
JP
Perchellet
Elisabeth M
EM
Crow
Kyle R
KR
Buszek
Keith R
KR
D000588:Amines / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D001547:Benzaldehydes / Q000737:chemistry; D002219:Carbamates / Q000737:chemistry; D003500:Cyclization; D015195:Drug Design; D007769:Lactams / Q000138:chemical synthesis / Q000494:pharmacology*; D007783:Lactones / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008956:Models, Chemical; D013237:Stereoisomerism; D014508:Urea / Q000737:chemistry
D000588:Amines; D000596:Amino Acids; D000900:Anti-Bacterial Agents; D001547:Benzaldehydes; D002219:Carbamates; D007769:Lactams; D007783:Lactones; C509476:octalactin A; D014508:Urea