title: Management of gingivobuccal complex cancer.
abstract: BACKGROUND
  Squamous cell carcinoma of the oral cavity ranks as the 12th most common cancer in the world and the 8th most frequent in males. It accounts for up to one-third of all tobacco-related cancers in India. Cancer of the gingivobuccal complex is especially common in Indians due to their tobacco habits. This review focuses on the management of lower gingivobuccal complex cancers.
  
  
  METHODS
  References for this review were identified by search of Medline and other bibliographic information available in the PubMed database. The search terms carcinoma oral cavity, and cancer oral cavity, buccal mucosa, gingiva, gingivobuccal complex, and alveolus cancer/carcinoma were used. References from relevant articles and abstracts from international conferences were also included. Only articles published in the English language were used.
  
  
  RESULTS
  Treatment of gingivobuccal complex cancer is primarily surgical. Radical neck dissection, or its modification, is the standard treatment for the node-positive neck. Supraomohyoid neck dissection is the accepted treatment for the node-negative neck. Radiotherapy is usually not the preferred modality of treatment for early gingivobuccal complex cancer. It is used either as postoperative adjuvant treatment or as definitive treatment for advanced cancer with or without chemotherapy. Chemotherapy has been used as neo-adjuvant, adjuvant or palliative treatment. Advanced cancers are common and continue to pose a challenge to the multidisciplinary team.
  
  
  CONCLUSIONS
  Gingivobuccal complex cancer remains a major public health problem despite being highly preventable and easily detectable. Advanced cancers constitute a major proportion of patients presenting for treatment. These patients are difficult to treat and have a poor outcome.
authors.affiliation: Department of Surgical Oncology, King George's Medical University, Lucknow, India. misralko@satyam.net.in
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Misra
authors.forename: Arun
authors.initials: A
authors.lastname: Chaturvedi
authors.forename: N C
authors.initials: NC
authors.lastname: Misra
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000628:therapy*; D005887:Gingival Neoplasms / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D037981:Neck Dissection / Q000379:methods; D009367:Neoplasm Staging
chemical_list: D000970:Antineoplastic Agents