title: Follicular recruitment is reduced in minimal stimulation for controlled ovarian hyperstimulation using purified human menopausal gonadotropin compared with follicle-stimulating hormone.
abstract: Ovulation induction using a minimal stimulation protocol with clomiphene citrate and highly purified hMG was associated with a 20% reduction in the number of follicles recruited compared with clomiphene citrate and recombinant FSH. This reduction may reduce the risk of multiple gestation without reducing the pregnancy rate.
authors.affiliation: Department of Gynecology and Obstetrics, Division of Reproductive Endocrinology and Infertility, Emory University School of Medicine, Atlanta, Georgia, USA. john.park@carolinaconceptions.com
authors.forename: John K
authors.initials: JK
authors.lastname: Park
authors.forename: Rachel
authors.initials: R
authors.lastname: Clark
authors.forename: Donna R
authors.initials: DR
authors.lastname: Session
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000494:pharmacology; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D008596:Menotropins / Q000494:pharmacology*; D015999:Multivariate Analysis; D006080:Ovarian Follicle / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D011272:Pregnancy, Multiple; D012189:Retrospective Studies
chemical_list: D005300:Fertility Agents, Female; D002996:Clomiphene; D008596:Menotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone