Cellular adhesion, proliferation and viability on conducting polymer substrates.
This work reports a comprehensive study about cell adhesion and proliferation on the surface of different electroactive substrates formed by pi-conjugated polymers. Biological assays were performed considering four different cellular lines: two epithelial and two fibroblasts. On the other hand, the electroactivity of the three conducting systems was determined in physiological conditions. Results indicate that the three substrates behave as a cellular matrix, even though compatibility with cells is larger for PPy and the 3-layered system. Furthermore, the three polymeric systems are electro-compatible with the cellular monolayers.
del Valle
Luis J
LJ
Departament d'Enginyeria Agroalimentaria i Biotecnología, ESAB, Universitat Politècnica de Catalunya, Castelldefels, Spain. luis.javier.del.valle@upc.edu
Estrany
Francesc
F
Armelin
Elaine
E
Oliver
Ramón
R
Alemán
Carlos
C
D000818:Animals; D001672:Biocompatible Materials; D002448:Cell Adhesion; D002460:Cell Line; D049109:Cell Proliferation; D002470:Cell Survival; D004285:Dogs; D006801:Humans; D008855:Microscopy, Electron, Scanning; D011108:Polymers / Q000378:metabolism*
D001672:Biocompatible Materials; D011108:Polymers