title: Nickel-catalyzed cross-coupling reactions of benzylic zinc reagents with aromatic bromides, chlorides and tosylates.
abstract: Benzylic zinc reagents prepared by direct insertion of zinc to benzylic chlorides in the presence of LiCl undergo smooth cross-coupling reactions with aromatic chlorides, bromides and tosylates using Ni(acac)(2) and PPh(3) as a catalyst system.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377 München, Germany.
authors.forename: Matthias A
authors.initials: MA
authors.lastname: Schade
authors.forename: Albrecht
authors.initials: A
authors.lastname: Metzger
authors.forename: Stephan
authors.initials: S
authors.lastname: Hug
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel
mesh_terms: D001593:Benzyl Compounds / Q000737:chemistry*; D001965:Bromides / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D014105:Tosyl Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D001593:Benzyl Compounds; D001965:Bromides; D002712:Chlorides; D014105:Tosyl Compounds; D009532:Nickel; D015032:Zinc