[Intrasal corticosteriods prescription to allergic rhinoconjunctivitis and rhinosinusitis during pediatric ages].
The different diseases that affect the upper respiratory tract, like allergic rhinitis, rhinoconjunctivitis, and rhinosinusitis have inflammation as their main pathophysiological component. Affects approximately 25% of the adults and 40% of the children. Intranasal corticosteroids (INSs) are considered the most effective treatment for the management of allergic rhinoconjunctivitis. Unlike antihistamines or antileukotrienes, INSs have a more profound effect on nasal congestion and the related sleep disturbance and daytime somnolence resulting from nasal congestion that affect their everyday quality of life. We review INSs mechanism of action, pharmacological properties of the different INSs, their therapeutic use and give our suggestions for their proper use.
Sacre Hazouri
José Antonio
JA
Instituto Privado de Alergia, Inmunología y Vías Respiratorias (INPAIR), Córdoba, Veracruz, México. sacre_1@hotmail.com
de la Torre González
Carlos
C
López González
Ana Luisa
AL
Alvarez Vega
Ricardo
R
D000284:Administration, Oral; D002648:Child; D003233:Conjunctivitis, Allergic / Q000188:drug therapy*; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
D005938:Glucocorticoids