A novel triterpenoid saponin from Polygala tenuifolia Willd.
A new triterpenoid saponin, tenuifoside A, was isolated together with three known triterpenoid saponins 2, 3, and 4 from the roots of Polygala tenuifolia Willd. With the help of chemical and spectral analyses (IR, MS, 1D-NMR, and 2D-NMR), the structure of the new saponin was elucidated as 3-O-beta-d-glucopyranosyl presenegenin 28-O-beta-d-xylopyranosyl-(1 --> 3)-beta-d-xylopyranosyl-(1 --> 4)-[beta-D-apiofuranosyl-(1 --> 3)]-alpha-L-rhamnopyranosyl-(1 --> 2)-[4-O-p-methoxycinnamoyl]-[alpha-l-rhamnopyranosyl-(1 --> 3)]-beta-d-fucopyranosyl ester (1). Three known triterpenoid saponins (2-4) were identified on the basis of spectroscopic data.
Xu
Tun-Hai
TH
Department of Traditional Chinese Medicine Chemistry, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Lv
Gang
G
Xu
Ya-Juan
YJ
Xie
Sheng-Xiu
SX
Zhao
Hong-Feng
HF
Han
Dong
D
Si
Yun-Shan
YS
Li
Yu
Y
Niu
Jian-Zhao
JZ
Xu
Dong-Ming
DM
D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D031801:Polygala / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
D012503:Saponins; D014315:Triterpenes; C532930:tenuifoside A