An optimum animal model for neonatal thoracoscopy.
OBJECTIVE
This study attempted to define an optimum animal model for neonatal thoracoscopy.


METHODS
Seven rabbits and three 5-7-kg piglets were subjected to thoracoscopy by three pediatric surgeons. The outcome for the successful completion of esophageal anastomosis and additional procedures, including diaphragmatic plication and lung biopsy, were noted.


RESULTS
Whereas esophageal anastomosis could be accomplished in all piglets, it could be achieved in only 1 rabbit. Additional procedures were possible in 2 piglets and no rabbits. Anesthetic complications were seen in 4 rabbits and 1 piglet.


CONCLUSIONS
Our findings suggest that the piglet may be the optimum animal model for replicating neonatal thoracoscopy. The fragility of the rabbit, coupled with a limited intrathoracic working space, limits its use for thoracoscopy.
Jones
Vinci S
VS
Department of Pediatric Surgery, The Children's Hospital at Westmead, Sydney, Australia. vincij@chw.edu.au
Wood
James G
JG
Godfrey
Craig
C
Cohen
Ralph C
RC
D000818:Animals; D006801:Humans; D007231:Infant, Newborn; D023421:Models, Animal; D011817:Rabbits; D013552:Swine; D013906:Thoracoscopy / Q000379:methods*