title: [Beyond dyssynchrony: what are the factors determining the response to cardiac resynchronization therapy?].
abstract: Although cardiac resynchronization therapy is currently used for treatment of refractory heart failure in patients with low ejection fraction and cardiac dyssynchrony, there is a substantial number of non-responders. This indicates that, in addition to cardiac dyssynchrony, there are other factors affecting response to cardiac resynchronization therapy. Pre-implant identification of these factors appears of crucial importance in order to finalize the resynchronization treatment to those patients who have the highest probability of a positive response. In this review the main non-dyssynchrony determinants of response to cardiac resynchronization therapy are presented and discussed.
authors.affiliation: UO di Cardiologia, Azienda Ospedaliera Universitaria, Ferrara. donatomele@libero.it
authors.forename: Donato
authors.initials: D
authors.lastname: Mele
authors.forename: Tiziano
authors.initials: T
authors.lastname: Toselli
authors.forename: Alessandro
authors.initials: A
authors.lastname: Dal Monte
authors.forename: Gabriele
authors.initials: G
authors.lastname: Guardigli
authors.forename: Claudio
authors.initials: C
authors.lastname: Ceconi
authors.forename: Roberto
authors.initials: R
authors.lastname: Ferrari
mesh_terms: D000368:Aged; D003663:Decision Trees; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial