Isolation and identification of a bacteriophage capable of infecting Streptococcus suis type 2 strains.
Streptococcus suis (S. suis) type 2 infection is considered to be a major problem worldwide in the swine industry. Studying phages of S. suis type 2 would be crucial for understanding the ecology and evolution of the Gram-positive bacteria. However, at the present, very little is known about them. An S. suis type 2 bacteriophage, named SMP, was isolated from nasal swabs of healthy Bama minipigs and was characterized at the microbiological and molecular levels. Phage SMP had an isometric head of 50 nm, a noncontractile tail of approximately 135 nm, and a linear double-stranded DNA genome. The host range of phage SMP was limited to 2 of 24 S. suis type 2 strains tested. The genome of phage SMP contained 36,216 bp with an average G+C content of 41.6%.
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Key Lab Animal Disease Diagnostic & Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, PR China.
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D020869:Gene Expression Profiling; D015967:Gene Expression Regulation, Viral; D016679:Genome, Viral; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D013045:Species Specificity; D017108:Streptococcus Phages / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D017011:Streptococcus suis / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
D014764:Viral Proteins