title: Invasive rhino-orbital fungal sinusitis following dental manipulation.
abstract: Rhinocerebral mucormycosis is a fulminant fungal infection of the nose and paranasal sinuses in immunocompromised patients. But mucormycosis following dental manipulation in immunocompetent patients leading to orbital involvement is rare. The objective of this study was to highlight the variable presentations of mucormycosis. We had two immunocompetent patients, who had undergone some dental treatment by quacks, later developed fulminant mucormycosis of the paranasal sinuses and blindness. The endoscopic sinus surgery and Amphotericin B chemotherapy resulted in a good outcome. This disease requires an aggressive approach of combined endoscopic sinus surgery and Amphotericin B to increase the chances of survival in these patients.
authors.affiliation: Department of ENT & HNS, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.
authors.forename: Hemant
authors.initials: H
authors.lastname: Chopra
authors.forename: Kapil
authors.initials: K
authors.lastname: Dua
authors.forename: Suneet
authors.initials: S
authors.lastname: Bhatia
authors.forename: Nisha
authors.initials: N
authors.lastname: Dua
authors.forename: Vikrant
authors.initials: V
authors.lastname: Mittal
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003729:Dental Care / Q000009:adverse effects*; D005658:Fungi / Q000302:isolation & purification / Q000502:physiology; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D009916:Orbital Diseases / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D012852:Sinusitis / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D055815:Young Adult
chemical_list: D000935:Antifungal Agents