title: Aspergillus sellar abscess: case report and review of the literature.
abstract: Aspergillus sellar abscess is a very rare form of fungal infections of the central nervous system (CNS). In this report, we describe the successful treatment of a patient with aspergillus sellar abscess. A 65-year-old woman presented with headache, nasal discharge and decreased visual acuity. The diagnosis of sellar mass was made on the basis of magnetic resonance imaging (MRI) examination. The computed tomography (CT) scan revealed sellar enlargement and sellar floor bony destruction. After hospitalization the patient underwent transsphenoidal surgery. Histopathological examination of the sellar mass revealed aspergillosis. Postoperatively, amphotericine-B and itraconazole therapy was started. During a six-month follow-up, the patient's headache and inertia disappeared, visual acuity improved. Aspergillus sellar abscess must be considered in the differential diagnosis of a sellar mass. The correct diagnosis of pituitary aspergillosis can only be achieved by histopathological examination. Surgical intervention and antifungal therapy should be considered the optimal treatment.
authors.affiliation: Department of Neurosurgery, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Wu Hou District, Chengdu-610 041, China.
authors.forename: Li
authors.initials: L
authors.lastname: Hao
authors.forename: Chen
authors.initials: C
authors.lastname: Jing
authors.forename: Cai
authors.initials: C
authors.lastname: Bowen
authors.forename: He
authors.initials: H
authors.lastname: Min
authors.forename: You
authors.initials: Y
authors.lastname: Chao
mesh_terms: D000038:Abscess / Q000150:complications* / Q000628:therapy; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D012658:Sella Turcica / Q000187:drug effects / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents