title: Arginine vasopressin in the treatment of vasodilatory septic shock.
abstract: Vasodilatory septic shock is characterized by profound vasodilation of the peripheral circulation, relative refractoriness to catecholamines and a relative deficiency of the posterior pituitary hormone, vasopressin. Arginine vasopressin is effective in restoring vascular tone in vasodilatory septic shock and may be associated with decreased mortality in less severe septic shock as well as improved mortality and decreased renal failure in septic shock patients at risk for renal failure.
authors.affiliation: University of British Columbia, Division of Critical Care, Department of Medicine, Kelowna General Hospital, BC, Canada. clholmes@telus.net
authors.forename: Cheryl L
authors.initials: CL
authors.lastname: Holmes
authors.forename: Keith R
authors.initials: KR
authors.lastname: Walley
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D012772:Shock, Septic / Q000188:drug therapy* / Q000503:physiopathology*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology*; D014667:Vasopressins / Q000172:deficiency
chemical_list: D014662:Vasoconstrictor Agents; D014667:Vasopressins; D001127:Arginine Vasopressin