TBOxCr(III)Cl-catalyzed enantioselective synthesis of 1,3-butadien-2-ylcarbinols.
A highly enantioselective synthesis of 1,3-butadien-2-ylcarbinols is achieved by using the TBOxCr(III)Cl catalyst and homoallenylbromide 1. This method can be further extended to the enantio- and regioselective propargylation of aldehydes.
Naodovic
Marina
M
Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
Xia
Guoyao
G
Yamamoto
Hisashi
H
D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D000432:Methanol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D002070:Butadienes; D009942:Organometallic Compounds; C532597:tethered bis(8-quinolinato)Cr(III)Cl; D000432:Methanol