title: [New and rarley used treatment options for refractory hand eczema: local UVA-1 phototherapy, retinoids, calcineurin inhibitors].
abstract: Hand eczema (HE) is one of the most frequent skin diseases. HE has a wide spectrum, with variable etiology, severity, and morphology. It often displays a chronically relapsing course with a poor prognosis, and has a high impact on the quality of life. Although different treatment options exist, the management of patients with chronic HE is often unsatisfactory. We highlight new and rarely used approaches to treat chronic HE uncluding local UVA-1-phototherapy, retinoids including the new oral retinoid alitretinoin, and calcineurin inhibitors.
authors.affiliation: Klinik für Dermatologie und Venerologie, Medizinische Hochschule Hannover, Ricklinger Strasse 5, 30449, Hannover, Deutschland. Raap.Ulrike@mh-hannover.de
authors.forename: U
authors.initials: U
authors.lastname: Raap
authors.forename: C
authors.initials: C
authors.lastname: Kenneweg
authors.forename: A
authors.initials: A
authors.lastname: Kapp
authors.forename: T
authors.initials: T
authors.lastname: Werfel
mesh_terms: D000284:Administration, Oral; D065095:Calcineurin Inhibitors; D002908:Chronic Disease; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004485:Eczema / Q000628:therapy*; D006229:Hand Dermatoses / Q000628:therapy*; D006801:Humans; D012008:Recurrence; D012176:Retinoids / Q000627:therapeutic use*; D014467:Ultraviolet Therapy / Q000639:trends*
chemical_list: D065095:Calcineurin Inhibitors; D003879:Dermatologic Agents; D012176:Retinoids