title: Aortic stenosis in the Dogue de Bordeaux.
abstract: OBJECTIVE
  To evaluate the occurrence of aortic stenosis and establish echocardiographic reference values in the Dogue de Bordeaux in Denmark.
  
  
  METHODS
  Fifty-three dogs were auscultated for evidence of a cardiac murmur and a full echocardiographic examination was performed. The criterion for the diagnosis of aortic stenosis was a peak aortic velocity greater than 2.5 m/s from a subcostal transducer location.
  
  
  RESULTS
  A left-basilar ejection murmur was detected in 38 (72 per cent) of the dogs. An aortic ejection velocity greater than 2.5 m/s was identified in 9 (17 per cent) of the dogs from a subcostal view. The aortic annulus in Dogue de Bordeaux was smaller than that considered normal in other breeds with comparable body size. Furthermore, a decreased aortoseptal angle was noticed in dogs with aortic stenosis.
  
  
  CONCLUSIONS
  The Dogue de Bordeaux may be highly predisposed to aortic stenosis. The small aortic annulus noted in healthy and affected Dogue de Bordeaux and a decreased aortoseptal angle noted in affected dogs in this study might reflect key aetiological features in the development of aortic stenosis.
authors.affiliation: Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Dyrlaegevej 16, 1870 Frederiksberg C, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Höllmer
authors.forename: J L
authors.initials: JL
authors.lastname: Willesen
authors.forename: A T
authors.initials: AT
authors.lastname: Jensen
authors.forename: J
authors.initials: J
authors.lastname: Koch
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D001947:Breeding; D003718:Denmark / Q000453:epidemiology; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology; D004285:Dogs; D004452:Echocardiography / Q000592:standards / Q000662:veterinary*; D005260:Female; D006326:Heart Auscultation / Q000662:veterinary; D006337:Heart Murmurs / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012016:Reference Values