[Transplantation of spermatogonial stem cells and prospects of its application].
Spermatogonial stem cells are male germ line stem cells, whose potency of proliferation is indispensable for the permanent production of male germ cells. With the advances in the technology of cryopreservation, in vitro culture and intracytoplasmic sperm injection (ICSI), the transplantation of spermatogonial stem cells is showing a splendid vista of application in basic medical research and clinical practice. This review briefly introduces the genesis and differentiation of spermatogonial stem cells, the current situation of their transplantation and the prospects of its application in medical science.
Wang
Yu-Bin
YB
Department of Urology, Shanghai Institute of Andrology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China.
Chen
Bin
B
Wang
Zheng
Z
D018929:Cell Culture Techniques; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D007248:Infertility, Male / Q000601:surgery; D008297:Male; D013093:Spermatogonia / Q000166:cytology*; D033581:Stem Cell Transplantation