title: [Obstructive sleep apnea syndrome and cardiovascular diseases].
abstract: Obstructive sleep apnea (OSA) syndrome is one of the most common respiratory disorders in humans. There is emerging evidence linking OSA to vascular disease, particularly hypertension. The underlying pathophysiological mechanisms that link OSA to cardiovascular diseases such as hypertension, congestive heart failure and atrial fibrillation are not entirely understood, although they certainly include mechanical events, increased sympathetic activity and oxidative stress. This review will examine the evidence and mechanisms linking OSA syndrome to cardiovascular disease.
authors.affiliation: Cardiologia e Fisiopatologia Cardiovascolare, Università e Azienda Ospedaliera di Perugia.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bentivoglio
authors.forename: Eva
authors.initials: E
authors.lastname: Bergamini
authors.forename: Marta
authors.initials: M
authors.lastname: Fabbri
authors.forename: Chiara
authors.initials: C
authors.lastname: Andreoli
authors.forename: Claudia
authors.initials: C
authors.lastname: Bartolini
authors.forename: Deborah
authors.initials: D
authors.lastname: Cosmi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Capasso
authors.forename: Paolo
authors.initials: P
authors.lastname: Bottini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ambrosio
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology; D015331:Cohort Studies; D045422:Continuous Positive Airway Pressure; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress; D017286:Polysomnography; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy