Cutaneous mucormycosis: report of five cases and review of the literature.
Mucormycosis is a highly aggressive fungal infection caused by Zygomycetes, from the order of Mucorales. This infection commonly presents an aggressive and rapid course and typically affects immunocompromised patients. Mucormycosis can manifest in different clinical patterns and locations. Although the correct diagnosis is often difficult, an early identification is essential for patient survival. Several clinical forms of mucormycosis are recognised. Cutaneous mucormycosis is less common than other clinical forms, but potentially lethal if treatment is not rapid. Tissue examination by histopathology and culture confirms the fungal infection. Standard treatment includes antifungal therapies associated with surgical debridement. We report five different cases of cutaneous mucormycosis treated in our institution and the management carried out in each case.
Arnáiz-García
M E
ME
Department of Plastic and Reconstructive Surgery, Infectious Diseases Unit, Marqués de Valdecilla University Hospital, Santander, Spain. elearnaiz@hotmail.com
Alonso-Peña
D
D
González-Vela
M del Carmen
Mdel C
García-Palomo
J D
JD
Sanz-Giménez-Rico
J R
JR
Arnáiz-García
A M
AM
D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods; D003881:Dermatomycoses / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D008297:Male; D009091:Mucormycosis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D016038:Skin Transplantation / Q000379:methods; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
D000935:Antifungal Agents