Overview of murine thrombosis models.
There are a myriad of options on where and how to perform thrombosis studies in mice. Models have been developed for systemic thrombosis, larger and smaller vessels of both the arterial and venous systems as well as several different microvascular beds. However, there are important differences between the models and investigators need to be careful and thoughtful when they choose which model to use.
Whinna
Herbert C
HC
Department of Pathology and Laboratory Medicine, School of Medicine, The University of North Carolina at Chapel Hill, NC 27599-7035, USA. whinna@med.unc.edu
D000818:Animals; D001158:Arteries / Q000293:injuries / Q000378:metabolism; D051379:Mice; D023421:Models, Animal; D013927:Thrombosis / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*; D014680:Veins / Q000293:injuries / Q000378:metabolism