title: [Genomic analysis of enterohemorrhagic Escherichia coli (EHEC) O157:H7 strains isolated in Saitama City].
abstract: To elucidate the origin of infection, we conducted epidemiological and bacteriological studies to clarify the origin of five sporadic outbreaks of enterohemorrhagic Escherichia coli (EHEC) O157:H7 between May and July 2007 in Saitama City and its outskirts. Of the 20 subjects were reported; including 6 patients and 5 infected persons, none of the 9 symptomatic subjects developed hemolytic-uremic syndrome. No association was confirmed between infection and food materials, but 11 organisms showed almost the same chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis. Our results suggested that these 5 sporadic outbreaks were part of a diffuse outbreak induced by an EHEC O157:H7 strain having a single origin.
authors.affiliation: S C Institute of Health Science and Research.
authors.forename: Koji
authors.initials: K
authors.lastname: Kikuchi
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kaetsu
authors.forename: Sumie
authors.initials: S
authors.lastname: Kobori
authors.forename: Akiko
authors.initials: A
authors.lastname: Yamamichi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ueno
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Inoue
authors.forename: Mariko
authors.initials: M
authors.lastname: Takano
authors.forename: Motonobu
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002876:Chromosomes, Bacterial / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification*; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000235:genetics* / Q000302:isolation & purification*; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male
chemical_list: D004269:DNA, Bacterial