title: Effects of dietary benzo[a]pyrene on growth and hematological parameters in juvenile rockfish, Sebastes schlegeli (Hilgendorf).
abstract: Experiments were conducted to evaluate the effect of dietary benzo[a]pyrene (B[a]P) on the growth and hematological parameters of rockfish, Sebastes schlegeli, after they were fed with subchronic dietary B[a]P for 30 days. The weight growth rate of the rockfish was significantly different from that of the control group at dietary B[a]P concentration of 1.5 and 2.0 mg/kg. Significant reduction in red blood cells, hematocrit, and hemoglobin were observed during 30 days of exposure to the highest concentration. Over 30 days, serum AST increased at a B[a]P concentration of 1.5 mg/kg and LDH increased at a B[a]P concentration of 1.0 mg/kg concentration. However, no changes were observed in ALT, total protein, magnesium or calcium.
authors.affiliation: Marine Environmental Management Team, National Fisheries Research and Development Institute, Busan 619-902, South Korea. cosmas@nfrdi.re.kr
authors.forename: Seong Gil
authors.initials: SG
authors.lastname: Kim
authors.forename: Dae Kuk
authors.initials: DK
authors.lastname: Park
authors.forename: Suck Woo
authors.initials: SW
authors.lastname: Jang
authors.forename: Jae Seong
authors.initials: JS
authors.lastname: Lee
authors.forename: Seong Soo
authors.initials: SS
authors.lastname: Kim
authors.forename: Mi Hee
authors.initials: MH
authors.lastname: Chung
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001564:Benzo(a)pyrene / Q000633:toxicity*; D001769:Blood / Q000187:drug effects*; D001772:Blood Cell Count; D001774:Blood Chemical Analysis; D004032:Diet; D004785:Environmental Pollutants / Q000633:toxicity*; D005399:Fishes / Q000502:physiology*; D006128:Growth / Q000187:drug effects*; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000097:blood; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D004785:Environmental Pollutants; D006454:Hemoglobins; D014874:Water Pollutants, Chemical; D001564:Benzo(a)pyrene; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase