title: Feruhermonins A-C: three daucane esters from the seeds of Ferula hermonis (Apiaceae).
abstract: Seventeen daucane esters have been isolated from the seeds of Ferula hermonis Boiss (Apiaceae). Three of these sesquiterpenes, 4beta-hydroxy-6alpha-benzoyl-7-daucen-9-one (1), 4beta, 8beta-dihydroxy-6alpha-benzoyl-dauc-9-ene (2), and 4beta, 9alpha-dihydroxy-6alpha-benzoyl-dauc-7-ene (4), named feruhermonins A-C, respectively, are novel natural products. The structures of these compounds were elucidated unequivocally by a series of 1D and 2D NMR analyses. Although 4beta, 8beta-dihydroxy-6alpha-(4-hydroxy-3-methoxybenzoyl)-dauc-9-ene (3) was reported previously, the complete spectroscopic data for this compound are presented here for the first time.
authors.affiliation: Phytochemistry Research Laboratory, Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, UK.
authors.forename: Abdurazag A
authors.initials: AA
authors.lastname: Auzi
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Gray
authors.forename: Mohamed M
authors.initials: MM
authors.lastname: Salem
authors.forename: Adnan A
authors.initials: AA
authors.lastname: Badwan
authors.forename: Satyajit D
authors.initials: SD
authors.lastname: Sarker
mesh_terms: D005309:Ferula / Q000737:chemistry*; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D012717:Sesquiterpenes