title: Evaluation of global left ventricular function assessment by dual-source computed tomography compared with MRI.
abstract: Left ventricular (LV) function assessment by dual-source computed tomography (DSCT) was compared with the reference standard method using magnetic resonance imaging (MRI). Accurate assessment of LV function is essential for the prediction of prognosis in cardiac disease. Thirty-four patients undergoing DSCT examination of the heart for various clinical indications underwent MRI after DSCT. Short-axis cine images were reconstructed from the DSCT datasets and were analyzed using a dedicated post-processing software-tool to generate global left ventricular function parameters. Five DSCT datasets were considered to be of insufficient image quality. DSCT showed a small overestimation of end-diastolic and end-systolic volumes of 11.0 ml and 3.5 ml, respectively. Myocardial mass assessed by DSCT showed an average underestimation of 0.2 g. DSCT showed a small overestimation of LV ejection fraction (LVEF) of 0.4%-point with a Bland-Altman interval of [-8.67 (0.40) 9.48]. Global LV functional parameters calculated from DSCT datasets acquired in daily clinical practice correlated well with MRI and may be considered interchangeable. However, visual assessment of the image quality of the short-axis cine slices should be performed to detect any artifacts in the DSCT data which could influence accuracy.
authors.affiliation: Thoraxcenter, Department of Cardiology, University Medical Centre Groningen, P.O. Box 30001, 9700 RB, Groningen, The Netherlands. p.a.van.der.vleuten@thorax.umcg.nl
authors.forename: Pieter A
authors.initials: PA
authors.lastname: van der Vleuten
authors.forename: Gonda J
authors.initials: GJ
authors.lastname: de Jonge
authors.forename: Daniël D
authors.initials: DD
authors.lastname: Lubbers
authors.forename: René A
authors.initials: RA
authors.lastname: Tio
authors.forename: Tineke P
authors.initials: TP
authors.lastname: Willems
authors.forename: Matthijs
authors.initials: M
authors.lastname: Oudkerk
authors.forename: Felix
authors.initials: F
authors.lastname: Zijlstra
mesh_terms: D000368:Aged; D017023:Coronary Angiography / Q000379:methods; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D011379:Prognosis; D015203:Reproducibility of Results; D012984:Software; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016277:Ventricular Function, Left