title: [A case-control study on depression and anxiety in hypertensive patients].
abstract: OBJECTIVE
  To study the current situation of depression and anxiety from patients with hypertension as well as to provide reference for the development of control and prevention program.
  
  
  METHODS
  Participants older than 35-year including both hypertensive patients and healthy controls were randomly selected in 2 communities of Pukou district in Nanjing through Health Behavior Survey. All the subjects were assessed by the Zung's self-rating depression scale (SDS) and the Zung's self-rating anxiety scale (SAS).
  
  
  RESULTS
  Raw score and index score of SDS and SAS were both significantly (P < 0.01) greater in hypertensive patients than in healthy control group. The prevalence of depression of 17.9% and anxiety of 9.5% in patient group were found significantly higher than that in healthy control group as 11.5% and 4.3%. Data from logistic regression model analysis showed that depression and anxiety were possible risk factors of hypertension (OR = 1.677, 95% CI: 1.013-2.776; OR = 2.451, 95% CI: 1.228-4.894). There was a combined effect seen between depression and anxiety (OR = 5.238, 95% CI: 2.356-11.664) but interaction did not appear.
  
  
  CONCLUSIONS
  Depression and anxiety were possibly associated with hypertension and more attention needs to be paid to the mental health situation of hypertensive patients in order to improve their quality of life.
authors.affiliation: Department of Epidemiology and Biostatistics, Public Health College, Southeast University, Nanjing 210009, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Han
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Yin
authors.forename: Fei
authors.initials: F
authors.lastname: Xu
authors.forename: Xin
authors.initials: X
authors.lastname: Hong
authors.forename: Ya-Qiong
authors.initials: YQ
authors.lastname: Liang
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Wang
mesh_terms: D000368:Aged; D001007:Anxiety / Q000453:epidemiology*; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors