title: Time course of accommodation after implantable collamer lens implantation.
abstract: OBJECTIVE
  To assess the time course of accommodative function after Implantable Collamer Lens (ICL) implantation and to investigate the relationship between patient age and accommodation in ICL-implanted eyes.
  
  
  METHODS
  Prospective, nonrandomized clinical trial.
  
  
  METHODS
  We prospectively examined 69 eyes of 40 consecutive patients with myopic refractive errors of -3.25 to -22.75 diopters (D) who were undergoing ICL implantation. We assessed the amplitude of accommodation using an accommodometer before and one, three, six, and 12 months after surgery. We also investigated its relationship with patient age.
  
  
  RESULTS
  The accommodation was 6.36 +/- 3.94 D (mean +/- standard deviation) before surgery and 4.89 +/- 2.72 D, 4.98 +/- 2.67 D, 5.16 +/- 2.72 D, and 5.72 +/- 2.85 D at one, three, six, and 12 months after surgery, respectively. The variance of data was statistically significant (P = .02, repeated-measures analysis of variance). Multiple comparisons demonstrated significant differences between measurements made before surgery and at one month after (P = .004, Fisher least significant difference test), before surgery and at three months after (P = .007), and before surgery and at six months after (P = .01). There was a significant correlation between patient age and accommodation before (Pearson correlation coefficient, r = -0.665; P < .001) and one year after (r = -0.803; P < .001) ICL implantation.
  
  
  CONCLUSIONS
  Accommodation was impaired transiently in the early postoperative periods, and then recovered gradually over time, indicating that transient dysfunction of the ciliary muscles by ICL fixation may occur after ICL implantation even if the crystalline lens remained intact. As patients aged, the amplitude of accommodation became significantly smaller not only in normal eyes but also in ICL-implanted eyes.
authors.affiliation: Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan. kamiyak-tky@umin.ac.jp
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Kamiya
authors.forename: Kimiya
authors.initials: K
authors.lastname: Shimizu
authors.forename: Daisuke
authors.initials: D
authors.lastname: Aizawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ishikawa
mesh_terms: D000065:Accommodation, Ocular; D000328:Adult; D000367:Age Factors; D002386:Cataract / Q000150:complications / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000601:surgery; D054120:Phakic Intraocular Lenses; D011183:Postoperative Complications; D011184:Postoperative Period; D013997:Time Factors