title: Microendoscopy of Reinke's space.
abstract: OBJECTIVE
  Contemporary surgical treatment of the superficial layer of the lamina propria or Reinke's space is most commonly performed through an incision in the overlying vocal fold epithelium. This approach may disrupt normal tissue, induce scarring, and allow extrusion of implanted materials. Previously reported external approaches to Reinke's space required either a laryngofissure or a "minithyrotomy" for access. These surgical approaches were performed without direct imaging of Reinke's space. Instruments placed below the vocal fold epithelium via this external approach were visualized through the translucent vocal fold epithelium. We designed this study to identify the feasibility of limited-access surgery of the lamina propria using microendoscopes placed into Reinke's space through an external approach.
  
  
  METHODS
  A cadaveric human larynx was dissected, and microendoscopes were directly advanced into Reinke's space through a subepithelial puncture of the cricothyroid membrane, as well as lateral fenestration through the thyroid cartilage.
  
  
  RESULTS
  Photodocumentation of the undersurface of vocal fold epithelium, the opposing surface of the vocal ligament, and the intervening Reinke's space was successfully accomplished.
  
  
  CONCLUSIONS
  Advances in both microendoscopes and accompanying instrumentation permit access to the superficial layer of the lamina propria without disrupting the overlying epithelium. This approach to microendoscopy of Reinke's space may allow for more effective surgical treatment of cysts, chronic edema, vascular abnormalities, atrophy, scarring, and sulcus vocalis.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1078, USA.
authors.forename: Henry T
authors.initials: HT
authors.lastname: Hoffman
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Bock
authors.forename: Lucy Hynds
authors.initials: LH
authors.lastname: Karnell
authors.forename: Janice
authors.initials: J
authors.lastname: Ahlrichs-Hanson
mesh_terms: D002102:Cadaver; D006801:Humans; D007820:Laryngeal Mucosa / Q000033:anatomy & histology / Q000601:surgery*; D007828:Laryngoscopy; D008297:Male; D014827:Vocal Cords / Q000033:anatomy & histology / Q000601:surgery*