title: A novel triterpenoid saponin from Polygala tenuifolia Willd.
abstract: A new triterpenoid saponin, tenuifoside A, was isolated together with three known triterpenoid saponins 2, 3, and 4 from the roots of Polygala tenuifolia Willd. With the help of chemical and spectral analyses (IR, MS, 1D-NMR, and 2D-NMR), the structure of the new saponin was elucidated as 3-O-beta-d-glucopyranosyl presenegenin 28-O-beta-d-xylopyranosyl-(1 --> 3)-beta-d-xylopyranosyl-(1 --> 4)-[beta-D-apiofuranosyl-(1 --> 3)]-alpha-L-rhamnopyranosyl-(1 --> 2)-[4-O-p-methoxycinnamoyl]-[alpha-l-rhamnopyranosyl-(1 --> 3)]-beta-d-fucopyranosyl ester (1). Three known triterpenoid saponins (2-4) were identified on the basis of spectroscopic data.
authors.affiliation: Department of Traditional Chinese Medicine Chemistry, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
authors.forename: Tun-Hai
authors.initials: TH
authors.lastname: Xu
authors.forename: Gang
authors.initials: G
authors.lastname: Lv
authors.forename: Ya-Juan
authors.initials: YJ
authors.lastname: Xu
authors.forename: Sheng-Xiu
authors.initials: SX
authors.lastname: Xie
authors.forename: Hong-Feng
authors.initials: HF
authors.lastname: Zhao
authors.forename: Dong
authors.initials: D
authors.lastname: Han
authors.forename: Yun-Shan
authors.initials: YS
authors.lastname: Si
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.forename: Jian-Zhao
authors.initials: JZ
authors.lastname: Niu
authors.forename: Dong-Ming
authors.initials: DM
authors.lastname: Xu
mesh_terms: D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D031801:Polygala / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D012503:Saponins; D014315:Triterpenes; C532930:tenuifoside A