Exploring the impact of depressive symptoms and medication beliefs on medication adherence in hypertension--a primary care study.
OBJECTIVE
This study aimed to assess the levels of adherence in a sample of hypertensive patients being cared for in primary care in Northern Ireland and to explore the impact of depressive symptoms and medication beliefs on medication adherence.


METHODS
The study was conducted in 97 community pharmacies across Northern Ireland. A questionnaire containing measures of medication adherence, depressive symptoms and beliefs about medicines was completed by 327 patients receiving antihypertensive medications.


RESULTS
Analysis found that 9.3% of participants were non-adherent with their antihypertensive medication (self-report adherence scale) and 37.9% had scores indicative of depressive symptoms as determined by the Center for Epidemiological Studies Depression Scale (CES-D). In the univariate analysis, concerns about medications had negative effects on both adherence and depressive symptomatology. However, logistic regression analysis revealed that patients over the age of 50 were more likely to be adherent with their medication than those younger than 50. Depressive symptomatology and medication beliefs (concerns) were not significantly related to adherence in the regression analysis.


CONCLUSIONS
Depressive symptomatology was high in the sample as measured by the CES-D. Age was the only significant predictor of medication adherence in this population.


CONCLUSIONS
Health care professionals should consider the beliefs of the patient about their hypertensive medications and counsel younger patients on adherence.
Maguire
Lisa K
LK
Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom. lisa.maguire@qub.ac.uk
Hughes
Carmel M
CM
McElnay
James C
JC
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003863:Depression / Q000523:psychology*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000523:psychology; D016015:Logistic Models; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D015999:Multivariate Analysis; D009660:Northern Ireland; D011320:Primary Health Care
D000959:Antihypertensive Agents