title: Regulation of flagellar length in Chlamydomonas.
abstract: Chlamydomonas reinhardtii has two apically localized flagella that are maintained at an equal and appropriate length. Assembly and maintenance of flagella requires a microtubule-based transport system known as intraflagellar transport (IFT). During IFT, proteins destined for incorporation into or removal from a flagellum are carried along doublet microtubules via IFT particles. Regulation of IFT activity therefore is pivotal in determining the length of a flagellum. Reviewed is our current understanding of the role of IFT and signal transduction pathways in the regulation of flagellar length.
authors.affiliation: Department of Anatomy and Cell Biology, Oklahoma State University Center for Health Sciences, Tulsa, OK 74107, United States. nedra.wilson@okstate.edu
authors.forename: Nedra F
authors.initials: NF
authors.lastname: Wilson
authors.forename: Janaki Kannan
authors.initials: JK
authors.lastname: Iyer
authors.forename: Julie A
authors.initials: JA
authors.lastname: Buchheim
authors.forename: William
authors.initials: W
authors.lastname: Meek
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000502:physiology; D016825:Chlamydomonas reinhardtii / Q000166:cytology* / Q000235:genetics; D005407:Flagella / Q000648:ultrastructure*; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D015800:Protozoan Proteins