Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli.
In a functional magnetic resonance imaging experiment, expectancy cues signaling emotional stimuli were used to study the personality trait of novelty seeking. BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability.
Bermpohl
Felix
F
Berenson-Allen Center for Non-Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. felix.bermpohl@charite.de
Pascual-Leone
Alvaro
A
Amedi
Amir
A
Merabet
Lotfi B
LB
Fregni
Felipe
F
Wrase
Jana
J
Schlagenhauf
Florian
F
Bauer
Michael
M
Heinz
Andreas
A
Schlaug
Gottfried
G
Northoff
Georg
G
D000339:Affect / Q000502:physiology*; D005106:Exploratory Behavior; D006801:Humans; D008279:Magnetic Resonance Imaging; D017397:Prefrontal Cortex / Q000502:physiology*; D013694:Temperament