[Advances in the research of cell electrofusion under microgravity].
Bioseperation, cell cultivation and cell electrofusion are three main biological processes in space laboratories. Microgravity is free from the influences of convection and sedimentation. Therefore, it is an ideal realm for cell electrofusion and hence it can be used in the research of monoclonal antibody, cross breeding and microgravity biology. This paper reviews the research of cell electrofusion under microgravity, including the changes of cytoskeleton and the mechanism of cell electrofusion.
Sun
Yan
Y
Department of Bioengineering, Beihang University , Beijing 100083, China. sunyan@buaa.edu.cn
Yuan
Yanhong
Y
Yi
Zongchun
Z
Zhuang
Fengyuan
F
Fan
Yubo
Y
D000818:Animals; D018929:Cell Culture Techniques; D002459:Cell Fusion / Q000379:methods*; D004558:Electric Stimulation; D018274:Electroporation / Q000379:methods*; D051379:Mice; D008839:Microelectrodes; D014893:Weightlessness; D018474:Weightlessness Simulation