Palladium-catalyzed 1,4-addition of terminal alkynes to unsaturated carbonyl compounds promoted by electron-rich ligands.
The efficient palladium-catalyzed conjugate addition of terminal alkynes to alpha,beta-unsaturated carbonyl compounds has been developed using electron-rich ligands, producing the corresponding gamma,delta-alkynyl ketone and gamma,delta-alkynyl esters in good yields.
Zhou
Lei
L
College of Chemistry, South China University of Technology, Guangzhou, 510640, PR China.
Chen
Liang
L
Skouta
Rachid
R
Jiang
Huan-feng
HF
Li
Chao-Jun
CJ