title: Comparative studies on the pathogenicity of cytopathic avian enteroviruses (avian nephritis virus) isolated from broiler chicks.
abstract: The pathogenicities of three cytopathic avian enteroviruses, strains AAF7, M-8, and G-4260 which were classified as avian nephritis viruses, were compared following inoculation into chicken kidney cell (CKC) cultures, embryonating eggs, and 1-day-old chicks. Strain M-8 produced the largest plaques, highest yields in CKC cultures, highest pathogenicity for embryonating eggs, and severest lesions in the kidney of experimentally-infected chicks. In contrast, strain AAF7 was the least pathogenic. All strains caused growth retardation and nephritis in experimentally-infected chicks.
authors.affiliation: Chemo-Sero-Therapeutic Research Institute, Shimizu-cho, Kumamoto, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takase
authors.forename: T
authors.initials: T
authors.lastname: Uchimura
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto