title: A cross-sectional study on aqueous humour lactate dehydrogenase level in retinoblastoma.
abstract: Lactate dehydrogenase enzyme is a non-specific marker found raised in different body fluids in various pathological conditions. This cross-sectional study was done in a medical college of Kolkata, India to find out lactate dehydrogenase level of aqueous humour in retinoblastoma cases. Aqueous humour lactate dehydrogenase level from 21 histology proved retinoblastoma cases and 21 controls was estimated and compared. Range of lactate dehydrogenase levels in retinoblastoma cases were 863-4819 IU/l; mean being 3396.9 IU/l; and in controls range was 48-146 IU/l; mean being 90.6 IU/l; 76.19% of retinoblastoma cases had value over 3000 IU/l. None of the controls had value above 150 IU/l. The difference between lactate dehydrogenase values of cases and controls was significant (p<0.001).
authors.affiliation: Department of Pathology, Midnapore Medical College and Hospital, Paschim Mednipur.
authors.forename: Subhalakshmi
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: Sambuddha
authors.initials: S
authors.lastname: Ghosh
authors.forename: Pradyot Narayan
authors.initials: PN
authors.lastname: Biswas
authors.forename: Subir Kumar
authors.initials: SK
authors.lastname: Dutta
authors.forename: Debnath
authors.initials: D
authors.lastname: Chattopadhyay
mesh_terms: D001082:Aqueous Humor / Q000201:enzymology*; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D011379:Prognosis; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000201:enzymology*; D012175:Retinoblastoma / Q000175:diagnosis / Q000201:enzymology*; D012720:Severity of Illness Index
chemical_list: D014408:Biomarkers, Tumor; D007770:L-Lactate Dehydrogenase