title: Discordance of motion artifacts on magnetic resonance imaging in Creutzfeldt-Jakob disease: comparison of diffusion-weighted and conventional imaging sequences.
abstract: OBJECTIVE
  Motion artifact is problematic in the diagnosis of Creutzfeldt-Jakob disease (CJD) because of dementia. The purpose was to compare the occurrence of this artifact between a diffusion-weighted (DW) magnetic resonance (MR) imaging sequence and conventional sequences.
  
  
  METHODS
  Ten MR examinations comprising T2-weighted, T1-weighted, DW, and fluid-attenuated inversion recovery imaging in seven CJD patients were retrospectively evaluated. The occurrence of motion artifacts on each sequence were assessed, and the examination was classified into four groups as follows: group A, motion artifact not revealed on DW imaging but revealed on one or more other sequences; group B, revealed on DW imaging and one or more other sequences; group C, not revealed on any sequences; and group D, revealed on DW imaging but not on any other sequences.
  
  
  RESULTS
  The 10 MR examinations were classified as eight group A (80%), one B (10%), one C (10%), and zero D (0%).
  
  
  CONCLUSIONS
  Motion artifacts are likely to occur in any conventional imaging sequences in CJD, but the fast-imaging ability of DW imaging can reduce this artifact. The combination of an absence of motion artifact on DW imaging and the presence on conventional sequences may be one of the frequent findings of CJD.
authors.affiliation: Department of Radiology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama 589-8511, Japan. shimono@med.kindai.ac.jp
authors.forename: Taro
authors.initials: T
authors.lastname: Shimono
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuboyama
authors.forename: Masatomo
authors.initials: M
authors.lastname: Kuwabara
authors.forename: Sung-Woon
authors.initials: SW
authors.lastname: Im
authors.forename: Yukinobu
authors.initials: Y
authors.lastname: Yagyu
authors.forename: Izumi
authors.initials: I
authors.lastname: Imaoka
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Ashikaga
authors.forename: Makoto
authors.initials: M
authors.lastname: Hosono
authors.forename: Takamichi
authors.initials: T
authors.lastname: Murakami
mesh_terms: D000368:Aged; D016477:Artifacts; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009038:Motion; D012189:Retrospective Studies