title: [Alginate-chitosan microspheres for the specific sorption of antibodies].
abstract: Potentially hemocompatible alginate-chitiosan microparticles and microcapsules coated with a semipermeable membrane with incorporated glycoconjugates were synthesized. The membrane acts as a barrier, which keeps the incorporated glycoconjugate from going outside but permits antibodies to penetrate inside and specifically bind to antigens, high-molecular polysaccharide conjugates. The carriers obtained are highly competitive in sorption capacity with Sepharose modified by the same oligosaccharides.
authors.forename: O E
authors.initials: OE
authors.lastname: Selina
authors.forename: A A
authors.initials: AA
authors.lastname: Chinarev
authors.forename: P S
authors.initials: PS
authors.lastname: Obukhova
authors.forename: A
authors.initials: A
authors.lastname: Bartkowiak
authors.forename: N V
authors.initials: NV
authors.lastname: Bovin
authors.forename: E A
authors.initials: EA
authors.lastname: Markvicheva
mesh_terms: D000327:Adsorption; D000464:Alginates; D000818:Animals; D001323:Autoantibodies / Q000302:isolation & purification*; D048271:Chitosan; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D006801:Humans; D008567:Membranes, Artificial; D051379:Mice; D008863:Microspheres; D009844:Oligosaccharides / Q000276:immunology
chemical_list: D000464:Alginates; D001323:Autoantibodies; D006603:Hexuronic Acids; D008567:Membranes, Artificial; D009844:Oligosaccharides; D020723:Glucuronic Acid; D048271:Chitosan