title: Intravenous magnesium sulphate infusion in the management of very severe tetanus in a child: a descriptive case report.
abstract: We report a 7-year-old boy with very severe tetanus treated with continuous infusion of magnesium sulphate for the control of spasms and severe autonomic dysfunction which was refractory to deep sedation and mechanical ventilation. The infusion was not associated with any adverse effects and he made an uneventful recovery. We recommend the use of intravenous magnesium sulphate infusion as an inexpensive and highly effective modality in severe tetanus.
authors.affiliation: Department of Child Health, Christian Medical College Hospital, Vellore, India. mammen.puliyel@gmail.com
authors.forename: Mammen M
authors.initials: MM
authors.lastname: Puliyel
authors.forename: Rajappan
authors.initials: R
authors.lastname: Pillai
authors.forename: Sophy
authors.initials: S
authors.lastname: Korula
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D001342:Autonomic Nervous System Diseases / Q000188:drug therapy / Q000209:etiology; D002648:Child; D006760:Hospitalization; D006801:Humans; D007262:Infusions, Intravenous; D008278:Magnesium Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D012121:Respiration, Artificial; D013035:Spasm / Q000150:complications / Q000188:drug therapy; D013742:Tetanus / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D008278:Magnesium Sulfate