title: Microelectrodes for studying neurobiology.
abstract: Microelectrodes have emerged as an important tool used by scientists to study biological changes in the brain and in single cells. This review briefly summarizes the ways in which microelectrodes as chemical sensors have furthered the field of neurobiology by reporting on changes that occur on the subsecond time scale. Microelectrodes have been used in a variety of fields including their use by electrophysiologists to characterize neuronal action potentials and develop neural prosthetics. Here we restrict our review to microelectrodes that have been used as chemical sensors. They have played a major role in many important neurobiological findings.
authors.affiliation: Department of Chemistry and Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599-3290, USA.
authors.forename: Justin M
authors.initials: JM
authors.lastname: Kita
authors.forename: R Mark
authors.initials: RM
authors.lastname: Wightman
mesh_terms: D000818:Animals; D005089:Exocytosis; D008839:Microelectrodes; D009446:Neurobiology / Q000295:instrumentation* / Q000379:methods*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D009569:Nitric Oxide / Q000378:metabolism; D014664:Vasodilation
chemical_list: D009569:Nitric Oxide