Chromoblastomycosis associated with Fonsecaea pedrosoi in a carpenter handling exotic woods.
Chromoblastomycosis is a rare, hard to diagnose disease that arises mostly in the tropics, especially in humid areas, affecting mainly males and rural workers. It is characterized by verrucous plaques or nodules that are slow growing and attributed to infection by different pigmented (dematiaceous) fungi. Usually the infection develops after injury, being primarily located on the lower extremities. The authors present the case of a healthy, 60-year-old man observed with a one year history of an erythematous violaceous 5cm tumor located on the right thigh. A biopsy specimen for histopathology revealed single or clustered brown pigmented cells, with a single or double septum and thick cell walls. Cultural smears showed growth of Fonsecaea Pedrosoi. The patient was treated with oral itraconazole (200mg per day), with a good response and clinical cure in 6 months that left only an atrophic scar.
Menezes
Nuno
N
Serviço de Dermatologia do Centro Hospitalar V.N. de Gaia (CHVNG), Portugal.
Varela
Paulo
P
Furtado
Antónia
A
Couceiro
Antonio
A
Calheiros
Ismália
I
Rosado
Laura
L
Mota
Gioconda
G
Baptista
Armando
A
D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification; D002862:Chromoblastomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D009784:Occupational Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D011174:Portugal; D013848:Thigh; D014934:Wood / Q000382:microbiology*
D000935:Antifungal Agents; D017964:Itraconazole