title: Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate.
abstract: Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.
authors.affiliation: Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, Department of Bio-images and Radiological Sciences, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cianfoni
authors.forename: M
authors.initials: M
authors.lastname: Wintermark
authors.forename: F
authors.initials: F
authors.lastname: Piludu
authors.forename: Q G
authors.initials: QG
authors.lastname: D'Alessandris
authors.forename: L
authors.initials: L
authors.lastname: Lauriola
authors.forename: M
authors.initials: M
authors.lastname: Visocchi
authors.forename: C
authors.initials: C
authors.lastname: Colosimo
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged
chemical_list: D003287:Contrast Media