[Early diagnosis of female genital tuberculosis by phage amplified biological assay].
OBJECTIVE
To establish an early diagnostic method for detecting female genital tuberculosis.


METHODS
Eighty-six women with genital tuberculosis during January 2005-September 2007 were examined by phage amplified biological assay, and the results were compared with those from leucorrhea culture, smear and PCR.


RESULTS
Forty-five patients were tuberculosis positive with 100% of specificity identified by phage amplified biological assay. Twenty patients were tuberculosis positive by PCR. Five patients were culture-positive tuberculosis and no case had smear-positive tuberculosis.


CONCLUSIONS
Phage amplified biologically assay is sensitive and specific, which could be used for the early diagnosis of female genital tuberculosis.
Liu
Bao-ying
BY
Department of Obstetrics and Gynecology, Guangzhou Chest Hospital, Guangzhou 510095, China. liubaoying169@sina.com
Li
Yan
Y
Zheng
Lei
L
Zhong
Mei
M
Yu
Yan-hong
YH
Xiong
Meng-zhou
MZ
D000293:Adolescent; D000328:Adult; D001431:Bacteriological Techniques / Q000379:methods; D001435:Bacteriophages; D001681:Biological Assay / Q000379:methods*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D012680:Sensitivity and Specificity; D014384:Tuberculosis, Female Genital / Q000175:diagnosis*; D055815:Young Adult