title: New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007.
abstract: This review summarizes selected articles appearing from January to December 2007 in the Journal of Allergy and Clinical Immunology. Articles were chosen that related to advances in mechanisms of chronic allergic inflammation and asthma, including those describing gene association studies, mast cells, IgE, eosinophils, cytokines, the inception of allergy, airway remodeling, preclinical therapeutic targets, and virally induced asthma.
authors.affiliation: Department of Medicine, University of California San Diego, La Jolla, CA 92093-0635, USA. dbroide@ucsd.edu
authors.forename: David
authors.initials: D
authors.lastname: Broide
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D016207:Cytokines / Q000276:immunology / Q000378:metabolism; D004804:Eosinophils / Q000276:immunology* / Q000378:metabolism; D000091344:Filaggrin Proteins; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D007073:Immunoglobulin E / Q000097:blood; D007249:Inflammation / Q000235:genetics / Q000276:immunology; D007381:Intermediate Filament Proteins / Q000276:immunology / Q000378:metabolism; D008407:Mast Cells / Q000276:immunology* / Q000378:metabolism; D011110:Polymorphism, Genetic; D011968:Receptors, Histamine / Q000276:immunology / Q000378:metabolism; D012141:Respiratory Tract Infections / Q000150:complications; D012907:Smoking; D018418:Th2 Cells / Q000276:immunology* / Q000378:metabolism; D014777:Virus Diseases / Q000150:complications
chemical_list: D018926:Anti-Allergic Agents; D016207:Cytokines; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins; D011968:Receptors, Histamine; D007073:Immunoglobulin E