The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Interpretation of exercise intolerance in COPD requires an integrated, multisystemic approach.
Neder
J Alberto
JA
Respiratory Medicine, Federal University of São Paulo, Brazil.
D017079:Exercise Tolerance / Q000502:physiology*; D006801:Humans; D010101:Oxygen Consumption / Q000502:physiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D015656:Respiratory Mechanics / Q000502:physiology