title: Genetic variation at three enzyme loci within a Thailand population of Opisthorchis viverrini.
abstract: Genetic variation among 231 individuals of Opisthorchis viverrini from the Ban Phai District, Khon Kaen Province (Thailand) was examined at three polymorphic enzymes: enolase (ENOL), phosphoglucomutase (PGM), and triose phosphate isomerase (TPI). Four alleles were detected for TPI and PGM, whereas only two alleles were detected for ENOL. The inferred genotype frequencies for both TPI and ENOL were not significantly different from Hardy-Weinberg equilibrium. In contrast, the inferred genotype frequencies for PGM showed a significant departure from Hardy-Weinberg equilibrium, with a lack of heterozygous individuals. This heterozygote deficiency suggests non-random mating and/or potentially high self fertilization.
authors.affiliation: Walai Rukhavej Botanical Research Institute, Mahasarakham University, Mahasarakham 44150, Thailand.
authors.forename: Weerachai
authors.initials: W
authors.lastname: Saijuntha
authors.forename: Paiboon
authors.initials: P
authors.lastname: Sithithaworn
authors.forename: Sopit
authors.initials: S
authors.lastname: Wongkham
authors.forename: Thewarach
authors.initials: T
authors.lastname: Laha
authors.forename: Rojchai
authors.initials: R
authors.lastname: Satrawaha
authors.forename: Neil B
authors.initials: NB
authors.lastname: Chilton
authors.forename: Trevor N
authors.initials: TN
authors.lastname: Petney
authors.forename: Ross H
authors.initials: RH
authors.lastname: Andrews
mesh_terms: D000483:Alleles; D000818:Animals; D003530:Cyprinidae / Q000469:parasitology; D005393:Fish Diseases / Q000469:parasitology*; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D009889:Opisthorchiasis / Q000469:parasitology / Q000662:veterinary*; D009891:Opisthorchis / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification; D010733:Phosphoglucomutase / Q000235:genetics; D010751:Phosphopyruvate Hydratase / Q000235:genetics; D013785:Thailand; D014305:Triose-Phosphate Isomerase / Q000235:genetics
chemical_list: D010751:Phosphopyruvate Hydratase; D014305:Triose-Phosphate Isomerase; D010733:Phosphoglucomutase