title: [Development of amniotic fluid-derived stem cell].
abstract: OBJECTIVE
  To review the latest development of amniotic fluid-derived stem cell(AFS) and to predict its future application.
  
  
  METHODS
  The recent articles about AFS were extensively reviewed. The origin,culture,identification,and directional differentiation as well as future application of AFS were summarized and discussed.
  
  
  RESULTS
  In 1993, AFS were thought to be exist possibly, and it was confirmed in recent years. AFS have some surface markers like other stem cells, and has multi-differentiated potential and extensive future application in cell therapy and tissue engineering approaches.
  
  
  CONCLUSIONS
  As a new stem cell, AFS remains to be further researched.
authors.affiliation: Center of Prenatal Diagnosis of Sichuan Province, West China Second Hospital, Sichuan University, Chengdu Sichuan, 610041, PR China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Zhang
authors.forename: Xinlian
authors.initials: X
authors.lastname: Chen
authors.forename: He
authors.initials: H
authors.lastname: Wang
authors.forename: Shanling
authors.initials: S
authors.lastname: Liu
mesh_terms: D000653:Amniotic Fluid / Q000166:cytology*; D000818:Animals; D002478:Cells, Cultured; D006801:Humans; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering