SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Seyfried
Irina
I
Hofbauer
Sebastian
S
Stoecher
Markus
M
Greil
Richard
R
Tinhofer
Inge
I
D000483:Alleles; D000970:Antineoplastic Agents / Q000494:pharmacology; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D016158:Genes, p53; D007093:Imidazoles / Q000494:pharmacology*; D066298:In Vitro Techniques; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000235:genetics*; D010879:Piperazines / Q000494:pharmacology*; D020641:Polymorphism, Single Nucleotide; D011401:Promoter Regions, Genetic; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors* / Q000235:genetics*
D000970:Antineoplastic Agents; D007093:Imidazoles; D010879:Piperazines; C482205:nutlin 3; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2