Regional chemotherapy: overview.
Regional chemotherapy was developed in the 1950s and continues to play an integral part in the development of newer therapies for advanced solid malignancies. Regional therapies have evolved in complexity but are still based on the pharmacokinetics of drug delivery to solid malignancies. Newer techniques demonstrate that the combination of regional therapies, hyperthermia, and surgery is essential in promoting improved patient outcomes.
Muchmore
James H
JH
Department of Surgery, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA. jmuchmo@aol.com
Wanebo
Harold J
HJ
D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000266:history; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000266:history / Q000379:methods; D002986:Clinical Trials as Topic; D049673:History, 20th Century; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents