Perforating necrobiosis lipoidica in a girl with type 1 diabetes mellitus: a new case reported.
Necrobiosis lipoidica is an idiopathic dermatological condition that is strongly associated with diabetes mellitus. It is more commonly seen in women than men. The average age of onset is 30-40 years. Necrobiosis Lipoidica diabeticorum is an extremely rare finding in childhood diabetes. We describe the case of a 13-year-old girl who has had type 1 diabetes mellitus since she was 8 years old. The patient presented with 2 well-defined, persistent plaques with a depressed central area and elevated purple peripheral ring, one on the right thigh and the other over the lateral left leg. Histopathologic evaluation of the patient's biopsy confirmed the diagnosis of necrobiosis lipoidica with transfollicular elimination. Our patient is the second pediatric case described with perforating necrobiosis lipoidica. We review the literature and discuss clinical features, several complications, and the most recent treatment options for necrobiosis lipoidica in diabetic children.
Hammami
Houda
H
Dermatology Department, Military Hospital of Tunis, Tunis, Tunisia.
Youssef
Soumaya
S
Jaber
Kahena
K
Dhaoui
Mohamed Raouf
MR
Doss
Nejib
N
D000293:Adolescent; D001707:Biopsy, Needle; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007328:Insulin / Q000627:therapeutic use; D035002:Lower Extremity; D009335:Necrobiosis Lipoidica / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D018570:Risk Assessment; D012720:Severity of Illness Index
D007328:Insulin