title: Prediction of peak forces for a shortening smooth muscle tissue subjected to vibration.
abstract: The objective of the present study is to investigate the peak forces for a tracheal smooth muscle tissue subjected to an applied longitudinal vibration following isotonic shortening. A non-linear finite element analysis was carried out to simulate the vibratory response under experimental conditions that corresponds to forced length oscillations at 33 Hz for 1 second. The stiffness change and hysteresis estimated from the experimental data was used in the analysis. The finite element results of peak forces are compared to the experimental data obtained. The comparison of results indicate that the approach and the vibratory response obtained may be useful for describing the cross-bridge de-attachments within the cells as well as connective tissue connections characteristic of tracheal smooth muscle tissue.
authors: Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA 23284-3015, USA. rmpidaparti@vcu.edu
authors: Ramana M
authors: RM
authors: Pidaparti
authors: Nandhini
authors: N
authors: Dhanaraj
authors: Richard A
authors: RA
authors: Meiss
mesh_terms: D000199:Actins / Q000378:metabolism; D000818:Animals; D001696:Biomechanical Phenomena / Q000379:methods; D003238:Connective Tissue / Q000502:physiology; D004285:Dogs; D004548:Elasticity; D020342:Finite Element Analysis; D007551:Isotonic Contraction / Q000502:physiology*; D053580:Muscle Strength / Q000502:physiology*; D009130:Muscle, Smooth / Q000502:physiology*; D009218:Myosins / Q000378:metabolism; D011237:Predictive Value of Tests; D012016:Reference Values; D014132:Trachea / Q000502:physiology; D014732:Vibration
chemical_list: D000199:Actins; D009218:Myosins