[Surgical treatment of primary hyperparathyroidism: our experience].
The Authors report their experience on 136 patients with primary hyperparathyroidism. Nephrolitiasis was proven in 56 patients (41.3%), 20 patients (14.7%) were asyntomatic. Acute primary hyperparathyroidism was detected in 12 cases (8.8%). The preoperative localization of the diseased glands permits to minimize the procedure in terms of length and region of incision, extent of exploration and morbidity. 91.3% of the lesions were single adenoma, 7.3% double adenomas and 1.4% hyperplasia in MEN 1. The intraoperative PTH assay, performed in 90 patients (66.2%), showed a sensibility of 93.4%. Surgical treatment was successful in 93.4% of cases ( 127/136 patients), increasing to 97.0% (132/136patients) if only recurrent hyperparathyroidism was considered, with no mortality and morbidity of 4.4%.
Casella
Claudio
C
Endocrinochirurgia, Università Studi di Brescia, Università degli Studi di Brescia, Cattedra di Chirurgia Generale.
Di Fabio
Francesco
F
Di Betta
Ernesto
E
Nascimbeni
Riccardo
R
Salerni
Bruno
B
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D016105:Parathyroidectomy; D011877:Radionuclide Imaging; D014463:Ultrasonography
D010281:Parathyroid Hormone