title: The effect of bed rest and an exercise countermeasure on leg venous function.
abstract: This study was performed to assess the effect of resistive vibration exercise during bed rest deconditioning on venous vascular dimension and function, as measured with ultrasound in the popliteal vein. Sixteen men were assigned to bed rest (BR-Ctrl) or bed rest with resistive vibration exercise (BR-RVE). Before and at 25 and 52 days of bed rest, popliteal vein diameter was measured at increasing cuff pressures. Venous capacitance and compliance were calculated from the pressure-volume curve. After 52 days of bed rest, BR-Ctrl showed no change in baseline popliteal vein diameter or compliance, while venous capacitance decreased. Resistive vibration exercise had no effect on the response in venous diameter, capacitance or compliance to 52 days of bed rest. The decline in venous capacitance due to long-term bed rest is not effectively counteracted by resistive vibration exercise, indicating that an alternative factor during bed rest deconditioning is responsible for venous changes.
authors: Department of Physiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. n.vanduijnhoven@fysiol.umcn.nl.
authors: Noortje T L
authors: NT
authors: van Duijnhoven
authors: Michiel W P
authors: MW
authors: Bleeker
authors: Patricia C E
authors: PC
authors: de Groot
authors: Dick H J
authors: DH
authors: Thijssen
authors: Dieter
authors: D
authors: Felsenberg
authors: Jörn
authors: J
authors: Rittweger
authors: Maria T E
authors: MT
authors: Hopman
mesh_terms: D000328:Adult; D001510:Bed Rest; D018493:Cardiovascular Deconditioning / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D011152:Popliteal Vein / Q000000981:diagnostic imaging / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology; D014463:Ultrasonography; D018924:Vascular Capacitance / Q000502:physiology; D014732:Vibration