title: Highly efficient construction of large molecular cavity using 1,3-alternate tetraoxacalix[2]arene[2]triazine as a platform.
abstract: In the presence of K(2)CO(3) in refluxing THF, dichloro-substituted tetraoxacalix[2]arene[2]triazine, a readily available macrocyclic compound from cyanuric acid chloride and benzyl 1,3-dihydroxybenzoate, underwent highly efficient nucleophilic displacement reactions with bis-nucleophilic reagents of different geometry, length and chirality in a 2+2 fashion to produce large and size-tunable cavity bis-tetraoxacalix[2]arene[2]triazines in good to excellent yields.
authors: Beijing National Laboratory for Molecular Sciences, Laboratory of Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China. mxwang@iccas.ac.cn
authors: Bao-Yong
authors: BY
authors: Hou
authors: Qi-Yu
authors: QY
authors: Zheng
authors: De-Xian
authors: DX
authors: Wang
authors: Zhi-Tang
authors: ZT
authors: Huang
authors: Mei-Xiang
authors: MX
authors: Wang
mesh_terms: D008958:Models, Molecular; D014227:Triazines / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D014227:Triazines