title: Artery-only occlusion may provide superior renal preservation during laparoscopic partial nephrectomy.
abstract: OBJECTIVE
  Artery-only occlusion (AO) has been used during nephron-sparing surgery to reduce ischemic damage. However, this has not been demonstrated in laparoscopic partial nephrectomy (LPN). We compared our experience with AO and both artery and vein occlusion (AV) in LPN to optimize the method of ischemia.
  
  
  METHODS
  This retrospective case-control study identified 25 patients who underwent AO during LPN and matched them to a cohort of 53 patients who underwent LPN with AV. The groups were compared for ischemia time, blood loss, transfusion rate, and renal function.
  
  
  RESULTS
  The 2 cohorts were comparable on demographic data. Blood loss was similar, with AO and AV demonstrating equivalent transfusion rates. The 2 cohorts had similar warm ischemia times. Positive margin rate was not affected by venous backflow in the AO cohort (0% AO vs 1.9% AV, P = .679). No significant postoperative change in creatinine (Cr) or creatinine clearance (CrCl) was seen for AO; however, a significant change in Cr and CrCl was seen in AV.
  
  
  CONCLUSIONS
  AO during LPN does not lead to a greater blood loss or an increased warm ischemia time. The benefit of AO on renal function is significant and requires further investigation.
authors: Section of Urology, Department of Surgery, University of Chicago, Chicago, IL 60637, USA. emgong@post.harvard.edu
authors: Edward M
authors: EM
authors: Gong
authors: Kevin C
authors: KC
authors: Zorn
authors: Marcelo A
authors: MA
authors: Orvieto
authors: Alvaro
authors: A
authors: Lucioni
authors: Lambda P
authors: LP
authors: Msezane
authors: Arieh L
authors: AL
authors: Shalhav
mesh_terms: D016022:Case-Control Studies; D003250:Constriction; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D007674:Kidney Diseases / Q000517:prevention & control*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control*; D012077:Renal Artery; D012082:Renal Veins; D012189:Retrospective Studies