title: Detection of HLA-antibodies prior to renal transplantation: prospects and limitations of new assays.
abstract: Donor-specific HLA antibodies are responsible for most early renal allograft rejections and allograft losses. Therefore, detection of HLA antibodies prior to transplantation is an important step in the evaluation of renal allograft recipients. In this mini-review we will describe recent advances in the techniques used to detect donor-specific HLA antibodies with emphasis on their potential application for patient management and their current limitations.
authors: Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
authors: Patrizia
authors: P
authors: Amico
authors: Gideon
authors: G
authors: Hönger
authors: Michael
authors: M
authors: Mayr
authors: Stefan
authors: S
authors: Schaub
mesh_terms: D005434:Flow Cytometry; D006084:Graft Rejection / Q000517:prevention & control*; D006680:HLA Antigens / Q000097:blood*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods*
chemical_list: D006680:HLA Antigens