title: Giant cell glioblastoma: review of the literature and illustrated case.
abstract: Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.
authors: Neurosurgery Service, São Marcos Hospital, Braga, Portugal.
authors: J M
authors: JM
authors: Valle-Folgueral
authors: L
authors: L
authors: Mascarenhas
authors: J A
authors: JA
authors: Costa
authors: F
authors: F
authors: Vieira
authors: J
authors: J
authors: Soares-Fernandes
authors: P
authors: P
authors: Beleza
authors: C
authors: C
authors: Alegria
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D017809:Fatal Outcome; D005909:Glioblastoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary; D008875:Middle Aged; D011379:Prognosis; D013120:Spinal Cord Neoplasms / Q000556:secondary