title: Amelanotic malignant melanoma in an acral location.
abstract: We present the case of a 74-year-old white female admitted to the Department of Dermatology because of a tumor in the IV-V interdigital area of her right foot. A crimson, dome-shaped tumor with a granular, spongy surface (diameter 4 cm) had developed over a period of about 3 months. The biopsy, stained with H and E, revealed an anaplastic malignant tumor. Additional immunochemical staining with Melan A allowed us to make the final diagnosis: amelanotic malignant melanoma (MM). The melanoma was removed by amputation of digits IV and V, with partial removal of the metatarsal bones (Clark degree 5, Breslow thickness 9 mm). Sentinel node biopsy was done using Tc99; it revealed no neoplastic alteration. The patient is still under oncological observation.
authors: Department of Dermatology, Venereology and Allergology, Medical University, Chalubinskiego 1, 50-368 Wroclaw, Poland. luke71@interia.pl
authors: Lukasz
authors: L
authors: Matusiak
authors: Andrzej
authors: A
authors: Bieniek
authors: Zdzislaw
authors: Z
authors: Wozniak
authors: Jacek Cezary
authors: JC
authors: Szepietowski
mesh_terms: D000368:Aged; D005260:Female; D005533:Foot Dermatoses / Q000473:pathology* / Q000601:surgery; D006801:Humans; D018328:Melanoma, Amelanotic / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*