[Chromosome 17 abnormalities in medulloblastomas and their prognostic value].
The cytogenetic profile of chromosome 17 was studied in 180 medlloblastomas by the interphasic FISH technique, which revealed the high incidence of this aberration and its association with the poor clinical course of the disease. The interphasic cytogenetic analysis of chromosome 17 abnormalities in medulloblastoma biopsy specimens may be recommended for its inclusion into a complex of laboratory diagnostic methods used in the examination of these tumors.
Korshunov
A G
AG
Sycheva
R V
RV
Gorelyshev
S K
SK
Ozerov
S S
SS
Golanov
A V
AV
D000293:Adolescent; D000328:Adult; D002528:Cerebellar Neoplasms / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D002869:Chromosome Aberrations; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D053208:Kaplan-Meier Estimate; D008297:Male; D008527:Medulloblastoma / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D011237:Predictive Value of Tests