title: Neuromyelitis optica in a young child with positive serum autoantibody.
abstract: Relapsing neuromyelitis optica is rare in children. The identification of a highly specific serum autoantibody marker (neuromyelitis optica-immunoglobulin G) differentiates neuromyelitis optica from other demyelinating disorders, particularly in clinically challenging cases. We present a child with multiple episodes of transverse myelitis and optic neuritis with positive neuromyelitis optica-immunoglobulin G titers, consistent with a diagnosis of relapsing neuromyelitis optica. Serial titers of neuromyelitis optica-immunoglobulin G normalized during remission.
authors: Division of Child Neurology, Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. .
authors: Ingrid P
authors: IP
authors: Loma
authors: Miya R
authors: MR
authors: Asato
authors: Robyn A
authors: RA
authors: Filipink
authors: Gulay
authors: G
authors: Alper
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000276:immunology; D009471:Neuromyelitis Optica / Q000175:diagnosis* / Q000276:immunology; D009902:Optic Neuritis / Q000175:diagnosis / Q000276:immunology; D012008:Recurrence
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G