title: [Physiologically active argon-based gas mixtures as a means of creating fire-safe gaseous environments in pressurized modules of varying purpose].
abstract: Development of acute hypoxic hypoxia in consequence of fire in various pressurized modules was studied. The investigation was aimed to look into the effects of inert argon and dramatic oxygen reduction in gaseous environment on animals (Wistar rats, mice c57bl/6, balb/c and f1cbaxbalb/c hybrids, Japanese quail embryos) and microorganism (Escherichia coli strains k-12 jf 238 and k-12 jm 83). Also, inflammability of some widely used materials was assessed in order to provide inputs to developers of fire-safe gaseous mixtures for pressurized habitats. It was shown that argon is favorable to survivability of animals and to maintenance of a high level of oxygen consumption. Gaseous mixtures with oxygen content less than 15 volume % suppressed burning of selected materials. Results of the investigation offer possibilities for designing new hypoxic fire-safe gas mixtures that will provide adequate human performance and ensure survival in extreme situations.
authors: P E
authors: PE
authors: Soldatov
authors: I A
authors: IA
authors: Smirnov
authors: T S
authors: TS
authors: Smolenskaia
authors: T S
authors: TS
authors: Gur'eva
authors: O A
authors: OA
authors: Dadasheva
authors: L A
authors: LA
authors: Lysenko
authors: V K
authors: VK
authors: Il'in
authors: Z O
authors: ZO
authors: Solov'eva
mesh_terms: D000208:Acute Disease; D032761:Animal Experimentation; D000818:Animals; D001128:Argon; D003370:Coturnix; D018504:Ecological Systems, Closed; D004926:Escherichia coli; D005390:Fires / Q000517:prevention & control*; D005740:Gases; D006801:Humans; D000860:Hypoxia / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D010101:Oxygen Consumption; D011784:Quail / Q000196:embryology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D005740:Gases; D001128:Argon