title: A case of Ludwig angina: a case report and review of the literature.
abstract: Ludwig angina is a rapidly progressing submaxillary, submandibular, and sublingual necrotizing cellulitis of the floor of the mouth that can have lethal consequences due to airway obstruction. Various aerobic and anaerobic microorganisms, and less often fungi, have been implicated to cause Ludwig angina, including oral flora such as streptococci and staphylococci. Early recognition and the use of parenteral antibiotics can prevent mortality and morbidity. We report a case of a 25-year-old white man who was admitted to the hospital by his dentist after being diagnosed with Ludwig angina secondary to periodontal abscesses involving teeth #17 and #32. Although antibiotics were administered, while in the hospital, the decedent had difficulty swallowing and was drooling. He suddenly began to have seizure-like activity thought to be anoxic myoclonus. The decedent was aggressively resuscitated and taken to the operating room for neck exploration and a tracheostomy. Neck exploration revealed severe necrotizing acute inflammation of the deep soft tissues and musculature of the neck. He remained on life support for 7 days until he was declared brain dead. Ludwig angina is a progressive cellulitis that often results in death by asphyxia. Ludwig angina can be complicated by subsequent deep neck infection. The underlying etiologies and common scenarios are examined, and significant autopsy findings and dissecting procedures are discussed. The pathophysiology of Ludwig angina is studied with a review of the current literature.
authors: Department of Pathology and Laboratory Medicine, Division of Forensic Pathology, Medical University of South Carolina, Charleston, South Carolina, USA. bradley.marcus@palmettohealth.org
authors: Bradley J
authors: BJ
authors: Marcus
authors: Jennifer
authors: J
authors: Kaplan
authors: Kim A
authors: KA
authors: Collins
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001237:Asphyxia / Q000209:etiology*; D001439:Bacteroides / Q000302:isolation & purification; D001926:Brain Death; D003680:Deglutition Disorders / Q000209:etiology; D004487:Edema / Q000473:pathology; D016983:Enterococcus / Q000302:isolation & purification; D004825:Epiglottis / Q000473:pathology; D049429:Forensic Pathology; D005881:Gingiva / Q000473:pathology; D006801:Humans; D008020:Life Support Care; D008158:Ludwig's Angina / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008168:Lung / Q000382:microbiology; D008297:Male; D009207:Myoclonus / Q000209:etiology; D009333:Neck / Q000382:microbiology / Q000473:pathology; D009334:Neck Muscles / Q000473:pathology; D009336:Necrosis; D012121:Respiration, Artificial; D012798:Sialorrhea / Q000209:etiology; D040521:Subcutaneous Tissue / Q000473:pathology; D013492:Suppuration
chemical_list: D000900:Anti-Bacterial Agents