[Correlation between structural and functional analysis in glaucoma suspects].
OBJECTIVE
To establish correlations between structural and functional parameters in glaucoma suspects.


METHODS
In 43 patients (83 eyes) of glaucoma patients we have performed standard automated perimetry, scanning laser polarimetry (GDx-VCC) of the retinal nerve fiber layer (RNFL) and optical coherence tomography (Stratus OCT) of the RNFL and optic disc.


RESULTS
Diagnostic concordance (achieved if one eye is deemed normal--respectively abnormal--by both tests) was 60.24% between perimetry and OCT respectively 61.44% between perimetry and GDx. The Areas under the Receiver Operating Characteristic curve were between 0.524-0.574 for OCT parameters and 0.518-0.548 for GDx parameters (considering the visual field examination as "gold standard"). The correlation between RNFL measurements in OCT and GDx took values between r = 0.481 and r = 0.352.


CONCLUSIONS
Structural and functional damage are not consistent with each other in early glaucoma, resulting in the fact that both tests should be used in the diagnostic strategy
Chiseliţă
D
D
Clinica I Oftalmologie, Iaşi.
Danielescu
C
C
Apostol
Alina
A
D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D003941:Diagnostic Techniques, Ophthalmological; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D007834:Lasers; D008875:Middle Aged; D012372:ROC Curve; D015203:Reproducibility of Results; D012383:Romania; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D041623:Tomography, Optical Coherence / Q000379:methods; D058609:Visual Field Tests / Q000379:methods