Ten-membered lactones from the marine-derived fungus Curvularia sp.
Investigation of the secondary metabolites of the marine-derived fungus Curvularia sp. yielded four new 10-membered lactones (1-4), along with the known modiolide A (5). The structures of 1-4 were characterized on the basis of spectroscopic and MS data and resemble known 10-membered lactones, but feature modified oxidation patterns around their macrocycles.
Greve
Hendrik
H
Institute for Pharmaceutical Biology, University of Bonn, Nussallee 6, D-53115 Bonn, Germany.
Schupp
Peter J
PJ
Eguereva
Ekaterina
E
Kehraus
Stefan
S
König
Gabriele M
GM
D001203:Ascomycota / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008386:Marine Biology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D000461:Rhodophyta / Q000382:microbiology
D007783:Lactones