title: [The relationship between the degradation of actin and the postmortem interval in rats].
abstract: OBJECTIVE
  To observe the degradation of actin in cardiac muscle, brain and skeletal muscle of rats after death and to find an objective parameter interval (PMI) estimation.
  
  
  METHODS
  Twenty eight clear Sprague Dawley rats put into an artificial climate incubator (set at 20 degrees C) for 0, 24, 48, 72, The actin contents in the above tissues were quantitated by Western-blot Pro Plus 5.0 image analysis system, and were then statistically analyzed
  
  
  RESULTS
  Actin content in all these tissues decreased gradually with prolonged differences between the groups was statistically significant (P < 0.05), with fastest, then the lung, the spleen, the liver, the kidney, the cardiac muscle order. There was a strong correlation between actin degradation and determination (R2) exceeded 0.75 in all these tissues.
  
  
  CONCLUSIONS
  degradation, the actin contents in cardiac muscle, liver, spleen, lung, kindey, rats decreased gradually with prolonged PMI, which may potentially be PMI estimation.
authors: School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
authors: Yang
authors: Y
authors: Liu
authors: Jin-Xia
authors: JX
authors: Kuai
authors: Yan-Wei
authors: YW
authors: Zhang
authors: Ying-Yuan
authors: YY
authors: Wang
mesh_terms: D000199:Actins / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D003643:Death; D005260:Female; D049429:Forensic Pathology / Q000379:methods*; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D011180:Postmortem Changes; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D000199:Actins