title: Macrocyclic nonviral vectors: high cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene.
abstract: New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transfection, have been obtained by attaching guanidinium groups at the lower rim of calix[4]arenes.
authors: Dipartimento di Chimica Organica e Industriale, Università di Parma, V.le G. P. Usberti 17/a, 43100 Parma, Italy.
authors: Valentina
authors: V
authors: Bagnacani
authors: Francesco
authors: F
authors: Sansone
authors: Gaetano
authors: G
authors: Donofrio
authors: Laura
authors: L
authors: Baldini
authors: Alessandro
authors: A
authors: Casnati
authors: Rocco
authors: R
authors: Ungaro
mesh_terms: D047250:Calixarenes / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*; D045744:Cell Line, Tumor; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004586:Electrophoresis; D019791:Guanidine / Q000737:chemistry*; D006801:Humans; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*; D010714:Phosphatidylethanolamines / Q000378:metabolism; D014162:Transfection / Q000295:instrumentation* / Q000379:methods*
chemical_list: C410262:1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine; D010636:Phenols; D010714:Phosphatidylethanolamines; C121325:calix(4)arene; D047250:Calixarenes; D004247:DNA; D019791:Guanidine