Tc-99m MIBI scintigraphy in tall cell variant of papillary thyroid carcinoma with negative radioiodine scan.
We report on a 45-year-old man who had a mass on the wall of the anterior right hemithorax. An excisional biopsy indicated carcinoma metastasis from thyroid malignancy. Tc-99m methoxyisobutyl isonitrile (MIBI) scintigraphy revealed markedly increased activity on the left side of the thyroid and the thoracic wall mass. Postoperative histology revealed a tall cell variant of papillary thyroid carcinoma. Whole body scintigraphy after radioiodine treatment was negative twice. However, Tc-99m MIBI and bone scintigraphy showed multiple soft tissue and bone metastases in the follow-up period. He died 3 years later because of complications of distant lung metastases.
Kaya
Meryem
M
Department of Nuclear Medicine, Hospital of the University of Trakya, Edirne, Turkey.
Cermik
Tevfik Fikret
TF
D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D051598:Whole Body Imaging / Q000379:methods*
D007457:Iodine Radioisotopes; D017256:Technetium Tc 99m Sestamibi