title: Coexistence of hepatocellular carcinoma (HCC) and c-Kit negative gastrointestinal stromal tumor (GIST): a case report.
abstract: A past history of sporadic solid cancers is disclosed in 10% of gastrointestinal stromal tumor (GIST) patients. Simultaneous occurrence with other malignancies is encountered in 14 to 16%, but the synchronous occurrence of GIST and hepatocellular carcinoma (HCC) has been reported only once in the English literature. An 81-year-old male patient is presented with a preoperatively known HCC, in whom a synchronous small nodular omental GIST adjacent to the lesser curvature of the stomach was incidentally discovered. When a GIST is encountered, a thorough intraoperative investigation of the abdominal cavity currently remains the only reliable method for detection of a possible coexisting malignancy.
authors: First Department of Surgery, University of Athens, Medical School, Laiko Hospital, Athens, Greece.
authors: Evangelos
authors: E
authors: Felekouras
authors: Petrou
authors: P
authors: Athanasios
authors: Stefani
authors: S
authors: Vgenopoulou
authors: Ioannis
authors: I
authors: Papaconstantinou
authors: Evangelos
authors: E
authors: Prassas
authors: Athanasios
authors: A
authors: Giannopoulos
authors: John
authors: J
authors: Griniatsos
mesh_terms: D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D017115:Catheter Ablation; D003937:Diagnosis, Differential; D046152:Gastrointestinal Stromal Tumors / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008297:Male; D009852:Omentum / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis
chemical_list: D019009:Proto-Oncogene Proteins c-kit