title: Keeping plants in shape: polycomb-group genes and histone methylation.
abstract: The Polycomb-group proteins (Pc-G) are transcriptional repressors that control many key developmental transitions in plants. Recent whole genome profiling of the histone methylation marks that are characteristic of the Pc-G have suggested many novel targets of Pc-G regulation. However, the number and nature of targets also suggests that Pc-G regulation may be much more dynamic than hitherto assumed. We discuss the role of histone methylation in gene regulation, the complexes involved in setting and reading the mark and how activity states may be reset during development.
authors: Institute of Genetics, Heinrich-Heine-University Duesseldorf, Universitaetsstr. 1, Germany.
authors: Nicole
authors: N
authors: Schatlowski
authors: Kate
authors: K
authors: Creasey
authors: Justin
authors: J
authors: Goodrich
authors: Daniel
authors: D
authors: Schubert
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D006657:Histones / Q000378:metabolism*; D046911:Macromolecular Substances; D008745:Methylation; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D010944:Plants / Q000235:genetics*; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins / Q000235:genetics*
chemical_list: D006657:Histones; D046911:Macromolecular Substances; D010940:Plant Proteins; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins