Long-alkyl-chain quaternary ammonium lactate based ionic liquids.
A new group of quaternary ammonium lactate based ionic liquids have been prepared and characterized. Didecyldimethylammonium (DDA) and benzalkonium (BA) D,L- and L-lactates are air-stable, hydrophilic, surface-active salts. They are very effective antibacterial and antifungal agents, especially the DDA lactates, against Streptococcus mutants and Candida albicans. Their activities are comparable or more effective than the original benzalkonium chloride. In addition, they have been shown to be good insect-feeding deterrents. However, they are poor antifungal agents for wood preservation. The toxicity of the DDA and BA lactates has also been studied and the results are presented in this paper.
Cybulski
Jacek
J
Industrial Chemistry Research Institute ul. Rydygiera 8, 01-793 Warsaw, Poland.
Wiśniewska
Anna
A
Kulig-Adamiak
Anna
A
Lewicka
Lidia
L
Cieniecka-Rosłonkiewicz
Anna
A
Kita
Kazimierz
K
Fojutowski
Andrzej
A
Nawrot
Jan
J
Materna
Katarzyna
K
Pernak
Juliusz
J
D000473:Alkanes / Q000737:chemistry*; D000818:Animals; D001419:Bacteria / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D005658:Fungi / Q000187:drug effects; D007313:Insecta / Q000502:physiology; D052578:Ionic Liquids / Q000737:chemistry* / Q000494:pharmacology / Q000633:toxicity; D019344:Lactic Acid / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D051381:Rats; D013499:Surface Properties; D014934:Wood / Q000187:drug effects
D000473:Alkanes; D052578:Ionic Liquids; D000644:Quaternary Ammonium Compounds; D019344:Lactic Acid