[A relationship of congenital brain malformations and tumor growth].
The peritumor-like areas of 12 cerebral hemispheric tumors were examined. Histological study revealed vascular malformations and/or congenital tissue dysplasias in all cases: cortical disorganization, neuronal heterotopy into the white matter, neural location in the molecular cortical layer, and persistence of a subpial granular cell layer. Immunohistochemical study using Ki-67 antibodies in the peritumor-like tissue dysplasias revealed proliferative activity in a number of cases. The associations of the origin of brain tumors and congenital malformations are discussed.
Grigor'ev
D G
DG
Cherstvyĭ
E D
ED
Stepanov
M E
ME
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D054022:Cerebrum / Q000002:abnormalities / Q000378:metabolism; D002648:Child; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000378:metabolism; D008297:Male; D054220:Malformations of Cortical Development / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism
D019394:Ki-67 Antigen; D009363:Neoplasm Proteins