A diffusive model of the ball and chain inactivation.
The ball and chain mechanism is a widely accepted theory for the inactivation of the Shaker K(+)channel. In this paper we propose a diffusive model that predicts a rate of inactivation that is comparable to the experimental measurements.
Borys
Przemyslaw
P
Department of Physical Chemistry and Technology of Polymers, Section of Physics and Applied Mathematics, Silesian University of Technology, Ks M Strzody 9, Gliwice, Poland. pborys@dione.cc
Grzywna
Zbigniew J
ZJ
D002462:Cell Membrane / Q000378:metabolism; D008956:Models, Chemical; D010455:Peptides / Q000378:metabolism; D011487:Protein Conformation; D051637:Shaker Superfamily of Potassium Channels / Q000737:chemistry*
D010455:Peptides; D051637:Shaker Superfamily of Potassium Channels