title: [If I were to wake up clumsy and shaking (10 years later)].
abstract: The diagnosis and treatment of early Parkinson's disease (PD) has undergone considerable changes in the last 10 years. Identification of genes responsible for familial forms of the disease as well as the possibility of detecting dopaminergic dysfunction before the appearance of motor symptoms has opened up the possibility of presymptomatic diagnosis. The concept of PD is changing. Therapeutic strategies are quite different. Several studies support the recommendation of not delaying the onset of dopaminergic therapies. Nonetheless, neuroprotection still has not been totally demonstrated and this continues to be an objective of priority.
authors: Centro de Investigación Parkinson, Policlínica Guipúzcoa, Parque Tecnológico de Miramón, San Sebastián. glinazasoro@terra.es
authors: G
authors: G
authors: Linazasoro
mesh_terms: D000818:Animals; D015259:Dopamine Agents / Q000627:therapeutic use; D006801:Humans; D010300:Parkinson Disease / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy; D013997:Time Factors
chemical_list: D015259:Dopamine Agents