[Clinical similarity and diagnostic difficulties in differentiation of diabetes mellitus type 1 and type 2 in adolescence - case report].
The authors would like to present the difficulties in differentiation of diabetes mellitus type 1 and type 2 in adolescence on the basis of two 17 years-old patients. In both patients' cases the following symptoms: polydipsia, polyuria and weight loss with hyperglycemia and glycosuria have been observed for a few months. During laboratory studies some additional abnormalities were observed: elevated HbA1c, dyslipidemia and high level of liver enzymes. Normal level of insulin as well as C-peptide lack of ketonuria and negative parameters of autoimmunologic reaction the supported diagnosis of diabetes mellitus type 2. Due to insulin therapy and metformin a correct level of glycemia was achieved.


CONCLUSIONS
Decompensated diabetes mellitus type 2 in adolescents may be difficult to differentiate with type 1.
Petriczko
Elzbieta
E
Klinika Pediatrii, Endokrynologii, Diabetologii, Chorob Metabolicznych i Kardiologii Wieku Rozwojowego, Szczecin, Poland. petrela1@wp.pl
Horodnicka-Józwa
Anita
A
Ostrowska
Iwona
I
Szmit-Domagalska
Justyna
J
Wójcik
Krystyna
K
Adamczyk
Teresa
T
Walczak
Mieczysław
M
D000293:Adolescent; D002096:C-Peptide / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008297:Male
D002096:C-Peptide; D007328:Insulin