[Peculiarity of cell energy metabolism in newborns with hypoxic-ischemic encephalopathy caused by asphyxia].
The authors have studied changes of activity of succinate dehydrogenase (SD) of peripheral blood lymphocytes of newborn with hypoxic-ischemic encephalopathy at early neonatal period and against cerebrokurin medicine administration. Newborn children with hypoxic-ischemic encephalopathy due to severe asphyxia have significant disturbancies of cyto-energy metabolism which is proved through decrease in activity index of SD and decrease in quantity of the cells with moderate and high activity. Lymphocytes of newborns with severe asphyxia were caracterized on six days by absence of the cells with moderate and high activity. Newborns with severe asphyxia who had been prescribed cerebrokurin had on their six days considerable increase in lymphocytes with moderate and high activity.
Znamen'ska
T K
TK
Pokhyl'ko
V I
VI
Koval'ova
O M
OM
D000596:Amino Acids / Q000008:administration & dosage / Q000627:therapeutic use; D001238:Asphyxia Neonatorum / Q000097:blood / Q000150:complications*; D004338:Drug Combinations; D004734:Energy Metabolism / Q000187:drug effects; D005865:Gestational Age; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000097:blood / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control; D007231:Infant, Newborn; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use; D013385:Succinate Dehydrogenase / Q000097:blood / Q000378:metabolism; D016896:Treatment Outcome
D000596:Amino Acids; D004338:Drug Combinations; D010455:Peptides; D013385:Succinate Dehydrogenase