Primary pulmonary synovial sarcoma, a rare primary lung neoplasm: two case reports and review of the current literature.
This report describes the clinical, histological and immunohistochemical features of two patients with primary pulmonary synovial sarcoma in the context of the literature. Chest pain, cough, haemoptysis and an enlarging pleural-based mass are the main clinical manifestations. Diagnosis depends on identifying epithelioid or spindle cells microscopically and on immunohistochemistry showing positivity for cytokeratin and vimentin and epithelial membrane antigen stains. Surgical excision is the main treatment approach.
Jiang
Jingjin
J
Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Zhou
Jianying
J
Ding
Wei
W
D000328:Adult; D002637:Chest Pain / Q000209:etiology; D003371:Cough / Q000209:etiology; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013584:Sarcoma, Synovial / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D014746:Vimentin / Q000378:metabolism
D014746:Vimentin; D007633:Keratins