title: The effects of examination stress on salivary cortisol, immunoglobulin A, and chromogranin A in nursing students.
abstract: This study aimed to assess the effects of examination stress on salivary cortisol, immunoglobulin A (IgA), and chromogranin A (CgA) in nursing students. Saliva samples were collected from 15 healthy females before and immediately after the one-hour examination, and two hours after the examination. Salivary cortisol, IgA, and CgA concentrations were determined by enzyme-linked immunosorbent assay. Both IgA and CgA concentrations statistically increased immediately after the examination (P < 0.05) and decreased two hours after the examination. No significant differences were observed between before and after the examination in the salivary cortisol concentration. These findings suggest that the acute stress due to the examination is associated with raised salivary IgA and CgA, but not cortisol.
authors: Department of Health Science, School of Nursing, Osaka Prefecture University, Osaka, Japan. takatsuj@nursing.osakafu-u.ac.jp
authors: Koichi
authors: K
authors: Takatsuji
authors: Yoshie
authors: Y
authors: Sugimoto
authors: Shoko
authors: S
authors: Ishizaki
authors: Yasuka
authors: Y
authors: Ozaki
authors: Etsuko
authors: E
authors: Matsuyama
authors: Yukari
authors: Y
authors: Yamaguchi
mesh_terms: D053379:Chromogranin A / Q000378:metabolism*; D004521:Educational Measurement; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D007070:Immunoglobulin A / Q000378:metabolism*; D011598:Psychoneuroimmunology; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D013312:Stress, Physiological / Q000378:metabolism*; D013338:Students, Nursing / Q000523:psychology; D014495:Universities
chemical_list: D053379:Chromogranin A; D007070:Immunoglobulin A; D006854:Hydrocortisone