Stereoselective iterative one-pot synthesis of N-glycolylneuraminic acid-containing oligosaccharides.
The use of an N-acyloxazolidinone-protected S-adamantanyl thiosialoside allows the highly stereoselective, one-pot multicomponent synthesis of alpha-sialoside-based oligosaccharides.
Crich
David
D
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, USA. dcrich@chem.wayne.edu
Wu
Baolin
B
D006801:Humans; D006868:Hydrolysis; D009438:Neuraminic Acids / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D023303:Oxazolidinones / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity
D009438:Neuraminic Acids; D009844:Oligosaccharides; D023303:Oxazolidinones; C032592:N-glycolylneuraminic acid