title: [Quantitative assessment of wall motion in gated SPECT using the centerline method].
abstract: Evaluation of myocardial wall motion is an important assessment of heart function. Specific analysis programs in nuclear medicine, such as QGS (quantitative gated SPECT) analysis and p-FAST (perfusion-function assessment for myocardial SPECT), have been used to assess wall motion, but they have not evaluated it through a comparison of normal data. The centerline method, using left ventriculograms (LVG), evaluates regional wall motion quantitatively through a comparison of normal data and patient data, and abnormality of wall motion is expressed in units of standard deviation (SD) s from the mean motion in a reference population. However, angiography is an invasive inspection, wall motion analysis is usually in one direction, and the conventional centerline method is not a three-dimensional analysis. The purpose of this study was to apply the centerline method to nuclear medicine and examine the wall motion of subjects through a comparison of normal wall motion non-invasively and in a three-dimensional way. We arranged the analysis program using C language and inspected it using a dynamic cardiac phantom and computed tomography (CT) scanner. We made a polar map that indicated the mean and SD of normal wall motion. Our proposed method was able to assess the wall motion of subjects quantitatively through a comparison of normal wall motion in nuclear medicine.
authors: Department of Radiology, University of Tokyo Hospital, Japan.
authors: Toshikazu
authors: T
authors: Imae
authors: Keita
authors: K
authors: Fujii
authors: Masaaki
authors: M
authors: Takano
authors: Junichi
authors: J
authors: Yamazaki
authors: Kyohito
authors: K
authors: Iida
authors: Kazuo
authors: K
authors: Mima
authors: Hiroyuki
authors: H
authors: Shinohara
mesh_terms: D000328:Adult; D005260:Female; D006321:Heart / Q000502:physiology*; D006334:Heart Function Tests / Q000379:methods*; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*