title: [Evans syndrome associated with idiopathic mixed-type autoimmune hemolytic anemia].
abstract: A 60-year-old man was admitted to our hospital with severe anemia and blood findings showed hemolytic anemia. Further serological examination revealed both warm-reactive autoantibody and cold agglutinin against erythrocytes. The cold agglutinin showed a low titer, 1 : 32 at 4 degrees C, and had a high thermal amplitude of 30 degrees C or higher, resulting in sufficient activity for hemolysis. Since no underlying disorders could be detected, the diagnosis was idiopathic mixed-type autoimmune hemolytic anemia. Although thrombocytopenia (Evans syndrome) subsequently appeared, corticosteroid was extremely effective for both anemia and thrombocytopenia. In this report we describe a rare case of Evans syndrome associated with mixed-type autoimmune hemolytic anemia, which had a dramatic response to corticosteroid therapy.
authors: Division of Hematology/Oncology, Department of Internal Medicine, Asahikawa City Hospital.
authors: Yasutaka
authors: Y
authors: Kakinoki
authors: Masako
authors: M
authors: Nagase
authors: Kohei
authors: K
authors: Okada
authors: Koji
authors: K
authors: Chiba
authors: Takashi
authors: T
authors: Fukuhara
authors: Takayoshi
authors: T
authors: Miyake
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*