title: Azathioprine in the management of autoimmune uveitis.
abstract: OBJECTIVE
  To evaluate the role of azathioprine as an immunosuppressive for steroid-resistant autoimmune uveitis (AIU).
  
  
  METHODS
  Patients using oral prednisolone for active AIU without clinical response were recruited. A standard protocol of oral prednisolone and azathioprine was used.
  
  
  RESULTS
  Twenty-seven patients participated in the study: 3 with anterior uveitis, 1 pars planitis, 4 idiopatic panuveitis, 8 Vogt-Koyonagi-Harada syndrome, 3 Behcet disease, and 8 choroidoretinopathies. Complete response was observed in 92%. Eleven patients had well-tolerated minor side effects.
  
  
  CONCLUSIONS
  Azathioprine is safe and effective in controlling steroid-resistant AIU.
authors: MRCOphth, Moorfields Eye Hospital, London, UK. patricio.pacheco@moorfields.nhs.uk
authors: Patricio A
authors: PA
authors: Pacheco
authors: Simon R J
authors: SR
authors: Taylor
authors: Miguel T
authors: MT
authors: Cuchacovich
authors: Gonzalo V
authors: GV
authors: Diaz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000188:drug therapy*; D001379:Azathioprine / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D014605:Uveitis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine