Growth and antioxidant system of Escherichia coli in response to microcystin-RR.
Microcystins are a kind of cyclic hepatoxins produced by many species of cyanobacteria. The toxic effects of microcystins on animals and plants have been well studied. However, the reports about the effects of microcystins on microbial cells are very limited. In present paper, Escherichia coli was undertaken to determine the effect of microcystin-RR. These results suggested that microcystin-RR could prolong the growth of E. coli when exposed to high concentrations of microcystin-RR and cause the accumulation of ROS and induce the oxidant stress for a short time. The antioxidant system protects E. coli from oxidative damage.
Yang
C Y
CY
State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan 430072, China.
Wang
W B
WB
Li
D H
DH
Liu
Y D
YD
D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D003124:Colorimetry; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development* / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008387:Marine Toxins; D052998:Microcystins / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D000975:Antioxidants; D008387:Marine Toxins; D052998:Microcystins; D017382:Reactive Oxygen Species; D017392:Thiobarbituric Acid Reactive Substances; C063855:microcystin RR; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione