title: Value of myocardial regional perfusion on long-term function in collateral-dependent myocardium.
abstract: BACKGROUND
  Collateral circulation is considered key for left ventricular (LV) function recovery in patients with chronic total occlusion (CTO). However, there are conflicting reports about the influence of collaterals on LV recovery after revascularization.
  
  
  METHODS
  Echocardiographic assessment of regional myocardial perfusion, wall motion score (WMS), and left ventricular ejection fraction (LVEF) were performed in patients with angiographically visible collateral circulation of grades 2 and 3.
  
  
  RESULTS
  The WMS and LVEF of group B (with presence of myocardial regional perfusion) were significantly improved at one month and six months compared to those of group A (with absence of myocardial regional perfusion). The correlation between myocardial regional blood flow and changes in WMS and LVEF was significant at 6 months in patients with angiographically visible collateral circulation of grade 2 and 3. Similar correlations were observed on myocardial contrast echocardiography (MCE) score index.
  
  
  CONCLUSIONS
  Myocardial function recovery in patients with CTO is determined by myocardial regional perfusion. MCE has important value for prognosis and risk stratification in patients with CTO undergoing cardiac catheterization.
authors: Division of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing City, People's Republic of China. jj.xqyy@yahoo.com.cn
authors: Jun
authors: J
authors: Jin
authors: Lan
authors: L
authors: Huang
authors: Hong
authors: H
authors: Wang
authors: Yao-Ming
authors: YM
authors: Song
authors: Ai-Ming
authors: AM
authors: Li
authors: Jun
authors: J
authors: Qin
authors: Xue-Jun
authors: XJ
authors: Yu
authors: Zhao-Hua
authors: ZH
authors: Geng
authors: Xiao-Bo
authors: XB
authors: Zhou
authors: Gang
authors: G
authors: Zhao
authors: Yun-Hua
authors: YH
authors: Gao
authors: Zhen
authors: Z
authors: Liu
authors: Li
authors: L
authors: Yang
authors: Hong-Mei
authors: HM
authors: Xia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003097:Collateral Circulation / Q000502:physiology*; D003287:Contrast Media; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy; D004452:Echocardiography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion; D011379:Prognosis; D018570:Risk Assessment; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D003287:Contrast Media