title: Surface properties and biocompatibility of acid-etched titanium.
abstract: The purpose of this study was to evaluate the effects of acid-etched titanium on the biological responses of osteoblast-like MC3T3-E1 cells. Four types of treatments (polishing, sandblasting, concentrated H2SO4 etching, and concentrated H2SO4 etching with vacuum firing) were carried out on the surfaces of commercially pure titanium (cpTi) disks. MC3T3-E1 cells were then cultured on the treated cpTi surfaces. Through surface roughness measurement and SEM analysis, it was found that the acid-etched surfaces showed higher roughness values than the sandblasted ones. Scanning electron microscope analysis showed that the cells on the disks treated with acid-etching and acid-etching with vacuum firing spread as well as the sandblasted ones. There were no significant differences in cell proliferation and collagen production on cpTi among the four different surface treatments. Based on the results of this study, it was concluded that etching with concentrated sulfuric acid was a simple and effective way to roughen the surface of titanium without compromising its biocompatibility.
authors: Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima 890-8544, Japan.
authors: Yukari
authors: Y
authors: Iwaya
authors: Miho
authors: M
authors: Machigashira
authors: Kenji
authors: K
authors: Kanbara
authors: Motoharu
authors: M
authors: Miyamoto
authors: Kazuyuki
authors: K
authors: Noguchi
authors: Yuichi
authors: Y
authors: Izumi
authors: Seiji
authors: S
authors: Ban
mesh_terms: D016475:3T3 Cells; D000134:Acid Etching, Dental; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D002448:Cell Adhesion; D002452:Cell Count; D002465:Cell Movement; D049109:Cell Proliferation; D048430:Cell Shape; D002478:Cells, Cultured; D003094:Collagen / Q000096:biosynthesis; D045662:Dental Etching; D003764:Dental Materials / Q000737:chemistry*; D003775:Dental Polishing; D006358:Hot Temperature; D051379:Mice; D008855:Microscopy, Electron, Scanning; D010006:Osteoblasts / Q000473:pathology*; D013464:Sulfuric Acids / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D014618:Vacuum
chemical_list: D001672:Biocompatible Materials; D003764:Dental Materials; D013464:Sulfuric Acids; D003094:Collagen; D014025:Titanium; C033158:sulfuric acid