[Molecular autopsy of sudden cardiac death: from postmortem to clinical approach].
Sudden cardiac death is one of the most prevalent cause of death in developed countries. Its aetiology varies according to the age. Some cardiac diseases may explain sudden death with minimal or no anatomic findings. However, many cardiac diseases, as for example channelopathies and hypertrophic cardiomyopathy have a genetic basis. Therefore genetic analyses (molecular autopsy) are becoming a useful tool in forensic medicine to identify the cause of sudden cardiac death and to improve the early diagnosis of asymptomatic carriers among relatives.
Michaud
Katarzyna
K
Unité de médecine forensique, Centre universitaire romand de médecine légale, Lausanne. Katarzyna.Michaud@chuv.ch
Lesta
Maria del Mar
Mdel M
Fellmann
Florence
F
Mangin
Patrice
P
D000328:Adult; D001344:Autopsy / Q000379:methods*; D009202:Cardiomyopathies / Q000235:genetics* / Q000473:pathology; D002312:Cardiomyopathy, Hypertrophic / Q000235:genetics / Q000473:pathology; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000473:pathology; D049429:Forensic Pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008133:Long QT Syndrome / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D013398:Sudden Infant Death / Q000209:etiology / Q000473:pathology