In vivo analysis of wound architecture in 700 microm microphakonit cataract surgery.
OBJECTIVE
To analyze the clear corneal wound architecture in 700 microm cataract surgery (microphakonit) using anterior segment optical coherence tomography (AS-OCT).


METHODS
Dr Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.


METHODS
Wound architecture was analyzed by AS-OCT 30 minutes after surgery and 1, 3, and 7 days postoperatively in 12 eyes (11 patients) that had microphakonit surgery. Five eyes had microphakonit with a 700 microm phaco tip with no intraocular lens (IOL) implantation, and 7 eyes had foldable IOL implantation after the main port was extended with a 2.8 mm keratome.


RESULTS
Twenty-four clear corneal wounds, which included the main port and the side port, were studied. The mean endothelial misalignment in the microphakonit wound was 0.085 mm +/- 0.09 (SD) immediately postoperatively, 0.057 +/- 0.07 mm at 1 day, 0.020 +/- 0.04 mm at 3 days, and 0.0 mm at 7 days. The mean coaptation loss was 0.030 +/- 0.06 mm immediately postoperatively, 0.029 +/- 0.04 mm at 1 day, and 0.029 +/- 0.04 mm at 3 days. There was a significant positive correlation between the change in stromal hydration and coaptation loss in the 17 wounds without extension; 82.3% of wounds at 3 days and 100% at 7 days had complete endothelial alignment.


CONCLUSIONS
Although there was no significant difference in endothelial misalignment, coaptation loss, or amount of stromal hydration between microphakonit wounds without and wounds with a 2.8 mm keratome extension, wound healing and resolution of coaptation loss or endothelial realignment occurred earlier in wounds without extension.
Agarwal
Amar
A
Doctor Agarwal's Eye Hospital and Eye Research Centre, 19 Cathedral Road, Chennai, Tamil Nadu, India. dragarwal@vsnl.com
Kumar
Dhivya Ashok
DA
Jacob
Soosan
S
Agarwal
Athiya
A
D003315:Cornea / Q000473:pathology* / Q000601:surgery; D003319:Corneal Stroma / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D008866:Microsurgery / Q000379:methods*; D018918:Phacoemulsification / Q000379:methods*; D041623:Tomography, Optical Coherence; D014945:Wound Healing