title: Corporeal grafting for severe hypospadias: a single institution experience with 3 techniques.
abstract: OBJECTIVE
  Correction of severe chordee by corporeal body grafting has been successfully performed using various grafts and biomaterials. We report a single institution comparison of our experience using small intestinal submucosa, tunica vaginalis and dermal grafts at stage 1 hypospadias repair.
  
  
  METHODS
  A retrospective chart review was performed of the records of all patients who underwent staged hypospadias repair from 1985 to 2006 with corporeal body grafting at stage 1 with small intestinal submucosa, tunica vaginalis or dermal grafts. Age at grafting, time between stages, residual chordee at stage 2 repair and the need for additional plication or chordee correction at stage 2 were recorded.
  
  
  RESULTS
  A total of 71 patients were identified with a median age of 10 months at stage 1 repair and a median of 7.6 months between stages 1 and 2 repair. Dermal grafts, tunica vaginalis and small intestinal submucosa grafts were used in 29, 21 and 20 patients, respectively. One patient received a combination of small intestinal submucosa and tunica vaginalis. None of the patients receiving tunica vaginalis graft required any further correction of chordee. One patient with a dermal graft and 1 receiving small intestinal submucosa required Nesbit plication at stage 2 repair for minor ventral chordee. One patients receiving small intestinal submucosa showed severe fibrosis at the graft site, requiring excision and repeat grafting with tunica vaginalis. This patient has been previously described. The 2 patients with small intestinal submucosa related complications had 4-ply grafts. We have seen no complications associated with 1-ply small intestinal submucosa. At limited followup we have not seen residual chordee after stage 2 repair.
  
  
  CONCLUSIONS
  In a large group of children requiring corporeal grafting for severe chordee we observed successful chordee correction with 1-ply small intestinal submucosa, tunica vaginalis or dermal grafts.
authors: Department of Urology, Indiana University, Indianapolis, Indiana 46202, USA.
authors: Jeffrey A
authors: JA
authors: Leslie
authors: Mark P
authors: MP
authors: Cain
authors: Martin
authors: M
authors: Kaefer
authors: Kirstan K
authors: KK
authors: Meldrum
authors: Rosalia
authors: R
authors: Misseri
authors: Richard C
authors: RC
authors: Rink
mesh_terms: D020405:Dermis / Q000637:transplantation*; D006801:Humans; D007021:Hypospadias / Q000601:surgery*; D007223:Infant; D007413:Intestinal Mucosa / Q000637:transplantation*; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D012189:Retrospective Studies; D012704:Serous Membrane / Q000637:transplantation; D014521:Urethra / Q000601:surgery; D013521:Urologic Surgical Procedures, Male / Q000379:methods*