title: The development of carbonate-containing apatite/collagen composite for osteoconductive apical barrier material.
abstract: The current report describes the properties of a new apical barrier material formulated from carbonate-containing apatite (CAp) and collagen. CAp particles of around 50 nm were deposited on reconstituted collagen fibers. CAp/col with about 60 wt % CAp (corresponding to apatite content of bone) was obtained after 1 day of calcification. CAp content increased up to about 80 wt % in a 15-day calcification reaction. CAp/col was composed of fine calcified collagen fibers. The crystallinity and Ca/PO(4) ratio of CAp were comparable to those of bone apatite. The mixture of CAp/col and saline reached a pH of about 9. The optimum powder-to-liquid ratio (P/L) to set into a root canal was determined to be 1.2. Furthermore, the mixture (P/L = 1.2) condensed in a root canal was liquid permeable. Thus, the CAp/col was expected as an apical barrier material with osteoconductivity.
authors: Department of Endodontics, Asahi University School of Dentistry, Gifu, Japan.
authors: Yoshihiro
authors: Y
authors: Takenaka
authors: Mayumi
authors: M
authors: Iijima
authors: Satoshi
authors: S
authors: Kawano
authors: Yasumitsu
authors: Y
authors: Akita
authors: Takakazu
authors: T
authors: Yoshida
authors: Yutaka
authors: Y
authors: Doi
authors: Ichiro
authors: I
authors: Sekine
mesh_terms: D001031:Apatites / Q000138:chemical synthesis / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D002113:Calcification, Physiologic; D002254:Carbonates; D025021:Cementogenesis; D003094:Collagen / Q000737:chemistry; D003432:Cross-Linking Reagents; D018360:Crystallography, X-Ray; D004338:Drug Combinations; D012387:Root Canal Filling Materials / Q000138:chemical synthesis* / Q000737:chemistry; D019227:Tooth Apex
chemical_list: D001031:Apatites; D001672:Biocompatible Materials; D002254:Carbonates; D003432:Cross-Linking Reagents; D004338:Drug Combinations; D012387:Root Canal Filling Materials; C030782:carboapatite; D003094:Collagen