The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture.
Drug-eluting stents (DES) have made a tremendous impact on the practice of percutaneous coronary intervention. Recently however, long-term DES failures have become a focal point, particularly with restenosis and thrombosis. An uncommon, yet important cause of DES failure is stent fracture. Of the two established first generation DES, the sirolimus-eluting stent (SES) has been particularly linked to cases of stent fracture, likely as a result of its closed cell design compared with other DES employing an open cell system. We present 2 cases of SES fracture confirmed using high-resolution intravascular optical coherence tomography giving unique insights into the in-vivo appearance of this complication.
Barlis
Peter
P
Sianos
Georgios
G
Ferrante
Giuseppe
G
Del Furia
Francesca
F
D'Souza
Savio
S
Di Mario
Carlo
C
D000368:Aged; D023903:Coronary Restenosis / Q000000981:diagnostic imaging* / Q000209:etiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D020123:Sirolimus / Q000008:administration & dosage*; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000706:statistics & numerical data; D014463:Ultrasonography
D020123:Sirolimus