title: [Etanercept as a possible trigger of fatal pulmonary fibrosis].
abstract: Pulmonary fibrosis can be caused by external agents, including certain drugs. For some time now, tumor necrosis factor antagonists such as etanercept have been used to treat certain autoimmune diseases. Fibrosis caused by medication responds to withdrawal of the drug and treatment with corticosteroids. Very rarely, fibrosis is irreversible. We present the case of a patient who developed pulmonary fibrosis after initiating treatment with etanercept. The clinical course was fulminant despite withdrawal of the drug and high doses of corticosteroids.
authors: Servicio de Neumología, Hospital de Móstoles, Móstoles, Madrid, Spain. jmdpas@hotmail.com
authors: Juan M
authors: JM
authors: Díez Piña
authors: Oscar
authors: O
authors: Vázquez Gómez
authors: Sagrario
authors: S
authors: Mayoralas Alises
authors: José D
authors: JD
authors: García Jiménez
authors: Dolores
authors: D
authors: Alvaro Alvarez
authors: M Paz
authors: MP
authors: Rodríguez Bolado
mesh_terms: D000328:Adult; D000068800:Etanercept; D017809:Fatal Outcome; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced*; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept