Recovery and sequence analysis of hepatitis a virus from springwater implicated in an outbreak of acute viral hepatitis.
An outbreak of acute hepatitis A virus in North Carolina was linked to drinking water from a contaminated shallow spring by phylogenetic analysis of hepatitis A virus (HAV) genomic sequences. Detection of HAV and fecal indicators in the water provided useful and timely information to assist with public health prevention and control measures.
Tallon
Lindsay A
LA
North Carolina Center for Public Health Preparedness, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. ltallon@hsph.harvard.edu
Love
David C
DC
Moore
Zack S
ZS
Sobsey
Mark D
MD
D015169:Colony Count, Microbial; D004196:Disease Outbreaks; D004755:Enterobacteriaceae / Q000302:isolation & purification; D005618:Fresh Water / Q000821:virology*; D005838:Genotype; D006506:Hepatitis A / Q000453:epidemiology* / Q000821:virology*; D030041:Hepatitis A virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009657:North Carolina / Q000453:epidemiology; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017421:Sequence Analysis; D017385:Sequence Homology
D012367:RNA, Viral