[The regulation of sigmaB activity and its role in some gram-positive food-borne pathogens--a review].
The alternative sigma factor sigmaB modulates the stress response of several Gram-positive bacteria. Not only does sigmaB play a prominent role in sporulation in the Gram-positive model organism Bacillus subtilis, but it also contributes both directly and indirectly to bacterial virulence in the food-borne human pathogens Bacillus cereus, Listeria monocytogenes and Staphylococcus aureus. As sigmaB has been shown to regulate expression of both virulence and virulence-associated genes, it indicates that sigmaB is a key player in pathogen ecophysiology.
Feng
Yingying
Y
Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Science, Central China Normal University, Wuhan, 430079, China.
Zhang
Xiaoli
X
Luo
Qin
Q
Zhou
Qingchun
Q
D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism*; D018441:Biofilms; D024881:Drug Resistance, Bacterial; D005516:Food Microbiology; D006094:Gram-Positive Bacteria / Q000145:classification / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D012808:Sigma Factor / Q000737:chemistry / Q000378:metabolism*
D001426:Bacterial Proteins; D012808:Sigma Factor