Diffuse periairway thickening in patients with Mikulicz disease.
A 70-year-old woman presented with dry mouth, bilateral swelling of the eyelids, and abnormal taste and smell sensations that had persisted for 3 years. She was diagnosed with Mikulicz disease and presented with dyspnea on exertion afterwards. Chest computed tomography and magnetic resonance imaging showed wall thickening of the trachea and bilateral bronchus. Transbronchial needle aspiration showed lymphoproliferative lesion in the tracheobronchus. The patient was treated with corticosteroid, which improved all of her clinical symptoms, computed tomography, and magnetic resonance findings. In this case, we presented a rare condition of coexistent Mikulicz disease with tracheobroncial wall thickening caused by lymphoproliferation without lesions in small airways or lung.
Sakashita
Akihiro
A
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Japan.
Nishimura
Yoshihiro
Y
Nogami
Munenobu
M
Kuramoto
Emi
E
Kono
Yuko
Y
Yamamoto
Masatsugu
M
Tamao
Natsumi
N
Ohtera
Hiroshi
H
Kobayashi
Kazuyuki
K
Funada
Yasuhiro
Y
Nishiuma
Teruaki
T
Kotani
Yoshikazu
Y
Ohno
Yoshiharu
Y
D000368:Aged; D001982:Bronchial Diseases / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000150:complications; D008279:Magnetic Resonance Imaging; D008882:Mikulicz' Disease / Q000150:complications* / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014133:Tracheal Diseases / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology