Stem cell transplantation programme at Singapore General Hospital.
The adult transplant programme at Singapore General Hospital (SGH) was established in 1985 and more than 820 transplants have been performed to date. An average of about 60 adult transplants (autologous and allogeneic) are performed each year. Transplants offered at SGH run the range from autologous to mismatched cord and unrelated transplants. Special interests of the transplant programme include non-myeloablative transplants in aplastic anaemia, cell therapy protocols including cytokine-induced killer cells, patterns of GVHD, cord blood transplantation for autoimmune diseases and graft engineering. A cGMP (good manufacturing practice) cell therapy laboratory was recently established to facilitate bench-to-bedside translational cell therapy trials. A BMT consortium has been formed among the various paediatric and adult transplant centres for harmonization of protocols and research activities.
Koh
Mbc
M
The Bone Marrow Transplant Programme, Department of Haematology, Singapore General Hospital, Singapore. mickey.koh.b.c.@sgh.com.sg
Goh
Yt
Y
Tan
Phc
P
Koh
Lp
L
Hwang
Wyk
W
Loh
Y
Y
Tan
D
D
Ng
Hj
H
Chuah
C
C
Lim
Tj
T
Niam
M
M
Suck
G
G
Chan
M
M
Phang
Cy
C
Lee
Jj
J
Wee
V
V
Ng
Hy
H
Lim
Ch
Ch
Yiu
R
R
Kam
G
G
Ang
A
A
Linn
Yc
Y
D000328:Adult; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology; D006239:Haplotypes; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D008875:Middle Aged; D012846:Singapore