title: Mortality of bullous pemphigoid: an evaluation of 223 patients and comparison with the mortality in the general population in the United States.
abstract: BACKGROUND
  There are large discrepancies in reported mortality for bullous pemphigoid (BP).
  
  
  OBJECTIVE
  We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects.
  
  
  METHODS
  Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2003 through our cutaneous immunofluorescence laboratory databases. The mortality of patients with BP was compared with that of age-matched control subjects in the general US population.
  
  
  RESULTS
  The 1-, 2-, and 5-year mortality was 0.23 (95% confidence interval=0.18, 0.29), 0.37 (95% confidence interval=0.31, 0.44), and 0.50 (95% confidence interval=0.42, 0.57), respectively. However, relative to age-matched control subjects, no difference in expected mortality was detected.
  
  
  CONCLUSIONS
  This was a retrospective cohort analysis.
  
  
  CONCLUSIONS
  Mortality of patients with BP is more likely related to advanced age and associated medical conditions than to disease-specific factors.
authors: Department of Dermatology at Emory University School of Medicine, and Grady Memorial Hospital, Atlanta, Georgia 30322, USA. srsingh@emory.edu
authors: Sareeta R S
authors: SR
authors: Parker
authors: Senait
authors: S
authors: Dyson
authors: Stacey
authors: S
authors: Brisman
authors: Michelle
authors: M
authors: Pennie
authors: Robert A
authors: RA
authors: Swerlick
authors: Rizwana
authors: R
authors: Khan
authors: Sue
authors: S
authors: Manos
authors: Benjamin D
authors: BD
authors: Korman
authors: Zongqi
authors: Z
authors: Xia
authors: Neil J
authors: NJ
authors: Korman
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002423:Cause of Death / Q000639:trends*; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000401:mortality*; D012189:Retrospective Studies; D017678:Sex Distribution; D015996:Survival Rate; D014481:United States / Q000453:epidemiology