Solubility prediction of solutes in aqueous mixtures of ethylene glycols.
The applicability of a trained version of the Jouyban-Acree model, for predicting the solubility of solutes in aqueous mixtures of ethylene glycol and its polymerized forms was shown. The solubilities of 8 drugs in binary mixtures were determined and the mean percentage deviation (MPD) was calculated as a prediction accuracy criterion and the overall MPD (+/- SD) was 23.2 (+/- 13.1)%.
Jouyban
A
A
Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ajouyban@hotmail.com
Soltanpour
S
S
Tamizi
E
E
D000465:Algorithms; D001682:Biological Availability; D005026:Ethylene Glycols / Q000737:chemistry*; D005544:Forecasting; D004364:Pharmaceutical Preparations / Q000737:chemistry; D011108:Polymers; D012995:Solubility; D013696:Temperature; D014867:Water
D005026:Ethylene Glycols; D004364:Pharmaceutical Preparations; D011108:Polymers; D014867:Water