Simplexidine, a 4-alkylpyridinium alkaloid from the Caribbean sponge Plakortis simplex.
Chemical analysis of the secondary metabolites of the Caribbean sponge Plakortis simplex, a source of many bioactive compounds, showed the presence of the new metabolite simplexidine (4), belonging to the extremely rare class of 4-alkyl-pyridinium alkaloids. The structural characterization of this molecule, based on spectroscopic methods, is reported.
Fattorusso
Ernesto
E
Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy. fattoru@nina.it
Romano
Adriana
A
Scala
Fernando
F
Taglialatela-Scafati
Orazio
O
D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D017691:Caribbean Region; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D047229:Plakortis / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000737:chemistry* / Q000378:metabolism
D000470:Alkaloids; D011726:Pyridinium Compounds; C532609:simplexidine