Complete follicular development and recovery of ovarian function of frozen-thawed, autotransplanted caprine ovarian cortex.
Frozen-thawed ovarian cortical fragments (1 mm(3)) were autotransplanted to the uterus of completely ovariectomized goats. The grafts developed preovulatory follicles, accompanied by estrous behavior and a rise in plasma E(2) levels, demonstrating successful cryopreservation and transplantation.
Santos
Regiane R
RR
Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Knijn
Hiemke M
HM
Vos
Peter L A M
PL
Oei
Christine H Y
CH
van Loon
Thijs
T
Colenbrander
Ben
B
Gadella
Bart M
BM
van den Hurk
Rob
R
Roelen
Bernard A J
BA
D000818:Animals; D015925:Cryopreservation / Q000379:methods*; D004967:Estrogens / Q000097:blood; D004971:Estrus / Q000097:blood / Q000502:physiology; D005260:Female; D006041:Goats; D023421:Models, Animal; D006080:Ovarian Follicle / Q000254:growth & development* / Q000502:physiology; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology*; D011374:Progesterone / Q000097:blood; D013739:Testosterone / Q000097:blood; D014182:Transplantation, Autologous / Q000379:methods*
D004967:Estrogens; D013739:Testosterone; D011374:Progesterone