title: [Possible triggers of decompensated chronic complex tinnitus with a therapeutic approach as relating to treatment of epilepsy].
abstract: Coxsackieviruses are responsible for numerable diseases in man. This is also the reason for the high prevalence of endemic infection rates in the population. Our analysis (working hypothesis) will focus on the participation of Coxsackieviruses in chronic decompensated, complex tinnitus. Examination of the Coxsackievirus antibody titers might reveal the extent to which a Coxsackieviruses-triggered disease of the central nervous system participates in the direct sequelae of tinnitus disorders. A spread of Coxsackieviruses to the auditory pathway might lead to an overstimulation of the auditory pathway, comparable to an epileptic lesion. Based on this assumption, treatment with an antiepileptic would make sense. The reasoning behind this working hypothesis is to find a potentially new diagnostic and therapeutic roadmap as a further guide for specialized clinics. The authors are well aware that previous results bear little relevance as they have been based on small case numbers.
authors: hcoors@chcoors.de
authors: H
authors: H
authors: Coors
authors: H
authors: H
authors: Stadtlaender
authors: V
authors: V
authors: Otto
authors: W
authors: W
authors: Schmidt
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D001304:Auditory Diseases, Central / Q000150:complications / Q000175:diagnosis*; D001306:Auditory Pathways; D002908:Chronic Disease; D003384:Coxsackievirus Infections / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D029822:Enterovirus B, Human; D006801:Humans; D008297:Male; D011000:Pleurodynia, Epidemic / Q000150:complications / Q000175:diagnosis; D014012:Tinnitus / Q000188:drug therapy* / Q000209:etiology*
chemical_list: D000927:Anticonvulsants