Performance of the BioPlex 2200 Autoimmune Vasculitis kit.
The BioRad BioPlex 2200 Vasculitis kit demonstrates excellent relative sensitivity and relative specificity for the semi-quantitative detection of IgG autoantibodies to MPO, PR3 and GBM. The fully-automated platform simultaneously measures three analytes in a single tube, offering superior advantage in speed and ease of use over current assays. The availability of a fully-automated platform with 24-hour availability for these three antibodies may be of considerable value in the differential diagnosis of patients with rapidly progressive glomerulonephritis.
Kaul
Ravi
R
BioPlex Division, Clinical Diagnostics Group, Bio-Rad Laboratories, Hercules, California 94547, USA. ravi_kaul@bio-rad.com
Johnson
Kim
K
Scholz
Heidi
H
Marr
Greg
G
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D003937:Diagnosis, Differential; D019719:Diagnostic Equipment; D004797:Enzyme-Linked Immunosorbent Assay; D005434:Flow Cytometry; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000276:immunology; D016179:Granulocyte Colony-Stimulating Factor / Q000276:immunology*; D006801:Humans; D018189:Immunomagnetic Separation; D007377:Interleukin-3 / Q000276:immunology*; D009195:Peroxidase / Q000276:immunology*; D011933:Reagent Kits, Diagnostic; D011993:Recombinant Fusion Proteins / Q000276:immunology*; D011994:Recombinant Proteins; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014657:Vasculitis / Q000175:diagnosis* / Q000276:immunology
D019268:Antibodies, Antineutrophil Cytoplasmic; D007377:Interleukin-3; D011933:Reagent Kits, Diagnostic; D011993:Recombinant Fusion Proteins; D011994:Recombinant Proteins; C404145:myelopoietin; D016179:Granulocyte Colony-Stimulating Factor; D009195:Peroxidase