Nicolau syndrome following intramuscular diclofenac injection: a case report.
Nicolau syndrome (NS) is a rare complication of intramuscular injection of various drugs which clinically presents with extensive necrosis of skin, subcutaneous and even muscle tissue. We describe a case of NS following intramuscular injection of diclofenac.
Panariello
Luigia
L
Department of Dermatology, University of Naples Federico II, Naples, Italy.
Ayala
Fabio
F
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects*; D005218:Fat Necrosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D012871:Skin Diseases / Q000139:chemically induced*; D013577:Syndrome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac