title: Current treatment concepts for neuromas-in-continuity.
abstract: A neuroma-in-continuity is a neuroma that results from failure of the regenerating nerve growth cone to reach peripheral targets. It occurs within an intact nerve in response to internally damaged fascicles, resulting in a distal portion of the nerve that no longer functions properly. Management of neuromas-in-continuity is challenging. Chemical methods, and microsurgical techniques including fascicular ligation, and burying into muscle and bone have been reported to prevent neuroma-in-continuity formation. The purpose of this article is to present novel techniques for neuroma-in-continuity management, and to discuss the related literature.
authors: First Department of Orthopaedics, Athens University Medical School, Athens, Greece. andreasfmavrogenis@yahoo.gr
authors: Andreas F
authors: AF
authors: Mavrogenis
authors: Kitty
authors: K
authors: Pavlakis
authors: Anna
authors: A
authors: Stamatoukou
authors: Panayiotis J
authors: PJ
authors: Papagelopoulos
authors: Stamatios
authors: S
authors: Theoharis
authors: Aristidis B
authors: AB
authors: Zoubos
authors: Zijie
authors: Z
authors: Zhang
authors: Panayotis N
authors: PN
authors: Soucacos
mesh_terms: D000818:Animals; D006801:Humans; D000922:Immunotoxins / Q000627:therapeutic use; D008866:Microsurgery / Q000379:methods; D009463:Neuroma / Q000209:etiology / Q000628:therapy*; D019635:Neurosurgical Procedures / Q000379:methods; D009498:Neurotoxins / Q000627:therapeutic use; D059348:Peripheral Nerve Injuries; D010524:Peripheral Nervous System Neoplasms / Q000209:etiology / Q000628:therapy*
chemical_list: D000922:Immunotoxins; D009498:Neurotoxins