Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".
Asara et al. (Reports, 13 April 2007, p. 280) reported sequencing of Tyrannosaurus rex proteins and used them to establish the evolutionary relationships between birds and dinosaurs. We argue that the reported T. rex peptides may represent statistical artifacts and call for complete data release to enable experimental and computational verification of their findings.
Pevzner
Pavel A
PA
Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, Mail Code 0404, La Jolla, CA 92093-0404, USA. ppevzner@cs.ucsd.edu
Kim
Sangtae
S
Ng
Julio
J
D000818:Animals; D002645:Chickens / Q000235:genetics; D003094:Collagen / Q000737:chemistry; D030562:Databases, Protein; D025061:Dinosaurs / Q000235:genetics; D005580:Fossils; D013058:Mass Spectrometry; D010455:Peptides / Q000737:chemistry*; D030162:Reptilian Proteins / Q000737:chemistry*; D020539:Sequence Analysis, Protein
D010455:Peptides; D030162:Reptilian Proteins; D003094:Collagen