First-trimester prenatal sonographic diagnosis of omphalocele-exstrophy-imperforate anus-spinal defects complex.
We describe a case of omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) diagnosed at 13 weeks' gestation by ultrasound detection of a large multilocular ventral wall mass into which inserted the umbilical cord, and thoracic hemivertebrae with kyphoscoliosis. Subsequent sonographic examinations at 16 and 19 weeks revealed evolution of the ventral wall mass into a classic omphalocele. Clinicians should recognize the significance of a large multicystic ventral wall mass, which should lead to a search for other anomalies suggestive of OEIS complex.
Wax
Joseph R
JR
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, 887 Congress Street, Suite 200, Portland, ME 04102, USA.
Pinette
Michael G
MG
Smith
Rosemarie
R
Cartin
Angelina
A
Blackstone
Jacquelyn
J
D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000000981:diagnostic imaging*; D000025:Abortion, Eugenic; D000328:Adult; D001006:Anus, Imperforate / Q000175:diagnosis / Q000000981:diagnostic imaging*; D001746:Bladder Exstrophy / Q000175:diagnosis / Q000000981:diagnostic imaging*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging; D006554:Hernia, Umbilical / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D013122:Spinal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D013131:Spine / Q000002:abnormalities / Q000000981:diagnostic imaging; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal / Q000379:methods*