title: Grey-scale and colour Doppler sonography in the evaluation of children with suspected bowel inflammation: correlation with colonoscopy and histological findings.
abstract: OBJECTIVE
  To evaluate the correlation of grey-scale and colour Doppler sonography with colonoscopy and histology to detect bowel inflammation in children.
  
  
  METHODS
  The records of 72 patients with suspected bowel inflammation were reviewed retrospectively. Patients were included in the study if sonography had been performed up to 30 days before colonoscopy. Grey-scale and colour Doppler sonography were used to evaluate bowel wall thickness and vascularity for the detection of distal bowel inflammation. Findings were correlated with colonoscopy and histological findings. The sensitivity and specificity of sonographic wall thickness to detect inflammation was determined. Spearman's coefficient (rs) was used to determine the correlation of Doppler findings with colonoscopy/histology.
  
  
  RESULTS
  Sonograms of 372 bowel segments were evaluated and results were correlated with colonoscopy and histological findings of 352 segments. The sensitivity and specificity of sonographic bowel thickness to detect inflammation in the terminal ileum and the right colon were high; in the other segments, specificity was high but sensitivity was low. The correlation of Doppler sonography with colonoscopy and histology to detect inflammation in the terminal ileum was strong (rs: 0.84; p<0.001) and in the other segments, weak to moderate; when the interval between examinations was shorter than 10 days, the correlation was stronger in all segments. Of nine patients with abnormal small bowel sonograms but normal colonoscopies, three had Crohn's disease.
  
  
  CONCLUSIONS
  Sensitivity and specificity of grey-scale sonography to detect inflammation in the terminal ileum and the right colon were high, and the correlation of Doppler with colonoscopy and histology was very strong in the same segments.
authors: Serviço de Gastroenterologia Pediátrica do Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. mepifanio@hotmail.com
authors: M
authors: M
authors: Epifanio
authors: M
authors: M
authors: Baldisserotto
authors: J V
authors: JV
authors: Spolidoro
authors: A
authors: A
authors: Gaiger
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007223:Infant; D015212:Inflammatory Bowel Diseases / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology*; D007422:Intestines / Q000098:blood supply / Q000473:pathology; D008297:Male; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color