[Experimental left orthotopic mono-pulmonary transplantation swine model].
The swine model is an orthotopic pulmonary transplantation model often uses in the transplantation experiments. The purpose of this study is to control the transplantation technique on swine model and perform the learning curve of this procedure, as much from surgical than anaesthetic point of view.


METHODS
20 orthotopic left pulmonary transplantations were performed on 20 pairs of domestic female pigs, weighting 30-35 kg. Tracheal intubation's time, monitoring time, bronchial, arterial and venous anastomosis time, warm ischemia time, were recorded. The causes of morbidity and mortality were also analyzed.


RESULTS
Bronchial anastomosis was a running mattress suture. All bronchial anastomoses were airtight. Arterial anastomosis was a running mattress end-to-end anastomosis. The venous return was carried out by a left atrium-venous running mattress suture anastomosis. Satisfied blood flows in all arterial and venous anastomoses were obtained.


CONCLUSIONS
We established an experimental swine model of pulmonary transplantation. The anaesthetic and surgical team performed their learning curve. Various anastomoses times and consequently, the total time of the intervention, were shortened.
Grigoroiu
Mădălina
M
Centrul de Chirurgie Generală şi Transplant Hepatic, Institutul Clinic Fundeni, Bucureşti.
Scarlat
C
C
Stănescu
C
C
Apriotesei
Roxana
R
Merlusca
G
G
Popescu
Andra
A
Trifan
B
B
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001980:Bronchi / Q000601:surgery*; D005260:Female; D016040:Lung Transplantation / Q000193:education / Q000379:methods*; D023421:Models, Animal; D011667:Pulmonary Veins / Q000601:surgery; D013552:Swine; D016896:Treatment Outcome