Normal glucose values are associated with a lower risk of mortality in hospitalized patients.
OBJECTIVE
Hyperglycemia is a common condition in hospitalized patients. The aim of this study was to investigate the relationships between glycemia upon admission and mortality in a heterogeneous group of adult patients.


METHODS
The 3-year records released from a general hospital were associated with a plasma glucose dataset of its general laboratory. A matched case-control study was implemented (3,338 case-control subject pairs). All-patient refined diagnosis-related groups and the relative risk of death were the matching criteria. A multivariate conditional logistic regression model was used to evaluate the associations between death and glycemia.


RESULTS
Higher in-hospital mortality was associated with hyperglycemia or hypoglycemia, whereas lower risk was observed for values between 78 and 101 mg/dl.


CONCLUSIONS
Our data confirm the relation between glycemia upon admission and mortality and suggest that slightly increased or decreased plasma glucose can be linked with increased mortality risk.
Bruno
Alberto
A
Diabetologia ASO San Giovanni Battista of Turin, Turin, Italy. abruno@molinette.piemonte.it
Gregori
Dario
D
Caropreso
Antonio
A
Lazzarato
Fulvio
F
Petrinco
Michele
M
Pagano
Eva
E
D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment / Q000706:statistics & numerical data; D012307:Risk Factors
D001786:Blood Glucose