title: [Precocious pubertal].
abstract: Precocious pubertal is frequent and should lead to a rigorous evaluation. It is important to precisely evaluate the timing of pubertal development, and to search for an hypothalamic lesion in cases of central precocious puberty. It is also important to recognize that many cases of precocious puberty will not progress and therefore do not need treatment. When central precocious puberty has been confirmed, GnRH agonists should be considered. Management issues, as well as long term results of these treatments are presented.
authors: Service d'endocrinologie-diabétologie pédiatrique, centre de référence des maladies endocriniennes rares de la croissance, hôpital Robert-Debré, Université Paris-Diderot Paris-7, 75935 Paris Cedex 19, France. jean-claude.carel@inserm.fr
authors: Jean-Claude
authors: JC
authors: Carel
authors: Delphine
authors: D
authors: Zenaty
authors: Anne
authors: A
authors: Paulsen
authors: Dominique
authors: D
authors: Simon
authors: Juliane
authors: J
authors: Léger
mesh_terms: D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D006801:Humans; D011629:Puberty, Precocious / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology* / Q000523:psychology
chemical_list: D007987:Gonadotropin-Releasing Hormone