title: Birth outcomes in women with eating disorders in the Norwegian Mother and Child cohort study (MoBa).
abstract: OBJECTIVE
  We explored the impact of eating disorders on birth outcomes in the Norwegian Mother and Child Cohort Study.
  
  
  METHODS
  Of 35,929 pregnant women, 35 reported broad anorexia nervosa (AN), 304 bulimia nervosa (BN), 1,812 binge eating disorder (BED), and 36 EDNOS-purging type (EDNOS-P) in the six months before or during pregnancy. The referent comprised 33,742 women with no eating disorder.
  
  
  RESULTS
  Pre-pregnancy body mass index (BMI) was lower in AN and higher in BED than the referent. AN, BN, and BED mothers reported greater gestational weight gain, and smoking was elevated in all eating disorder groups. BED mothers had higher birth weight babies, lower risk of small for gestational age, and higher risk of large for gestational age and cesarean section than the referent. Pre-pregnancy BMI and gestational weight gain attenuated the effects.
  
  
  CONCLUSIONS
  BED influences birth outcomes either directly or via higher maternal weight and gestational weight gain. The absence of differences in AN and EDNOS-P may reflect small numbers and lesser severity in population samples. Adequate gestational weight gain in AN may mitigate against adverse birth outcomes. Detecting eating disorders in pregnancy could identify modifiable factors (e.g., high gestational weight gain, binge eating, and smoking) that influence birth outcomes.
authors: Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599-7160, USA. cbulik@med.unc.edu
authors: Cynthia M
authors: CM
authors: Bulik
authors: Ann
authors: A
authors: Von Holle
authors: Anna Maria
authors: AM
authors: Siega-Riz
authors: Leila
authors: L
authors: Torgersen
authors: Kari Kveim
authors: KK
authors: Lie
authors: Robert M
authors: RM
authors: Hamer
authors: Cecilie Knoph
authors: CK
authors: Berg
authors: Patrick
authors: P
authors: Sullivan
authors: Ted
authors: T
authors: Reichborn-Kjennerud
mesh_terms: D000328:Adult; D001724:Birth Weight; D016022:Case-Control Studies; D001068:Feeding and Eating Disorders / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009664:Norway / Q000453:epidemiology; D016012:Poisson Distribution; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012044:Regression Analysis