title: High-resolution 14N-edited 1H-13C correlation NMR experiment to study biological solids.
abstract: It was recently shown that nuclear magnetic resonance (NMR) spectra of nitrogen-14 (spin I=1) can be obtained by indirect detection via spin S=1/2 nuclei in powders spinning at the magic angle. An increased number of solid-state NMR methods are now available to tailor sequences for specific purposes, e.g., hetero-nuclear dipolar recoupling or homo-nuclear dipolar decoupling schemes. Here, we combine the latest recoupling and decoupling techniques to obtain high-resolution (1)H-(13)C through-space correlation spectra, where only the correlation peaks of those carbons close to nitrogen nuclei are observed. The experiment is demonstrated on a (13)C enriched l-histidine. HCl x H(2)O powder sample.
authors: Unité de Catalyse et Chimie du Solide, UMR-CNRS 8181, Université de Lille 1, 59652 Villeneuve d'Ascq cedex, France. jean-paul.amoureux@univ-lille1.fr
authors: Jean-Paul
authors: JP
authors: Amoureux
authors: Julien
authors: J
authors: Trébosc
authors: Bingwen
authors: B
authors: Hu
authors: Nicholas
authors: N
authors: Halpern-Manners
authors: Sasa
authors: S
authors: Antonijevic
mesh_terms: D001704:Biopolymers / Q000032:analysis* / Q000737:chemistry*; D002247:Carbon Isotopes / Q000737:chemistry*; D006639:Histidine / Q000032:analysis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009584:Nitrogen / Q000737:chemistry*; D011522:Protons; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D001704:Biopolymers; D002247:Carbon Isotopes; D011522:Protons; D006639:Histidine; D009584:Nitrogen