title: Cocoa butter lotion for prevention of striae gravidarum: a double-blind, randomised and placebo-controlled trial.
abstract: OBJECTIVE
  To assess whether application of cocoa butter lotion reduces the development of striae gravidarum (SG).
  
  
  METHODS
  Multicentre, double-blind, randomised and placebo-controlled trial.
  
  
  METHODS
  Beirut and Tripoli, Lebanon.
  
  
  METHODS
  Nulliparous women presenting for prenatal care.
  
  
  METHODS
  Nulliparous women presenting in the first trimester were randomly assigned to receive a lotion containing cocoa butter or a placebo lotion. Women were instructed to apply the assigned lotion daily until delivery.
  
  
  METHODS
  The development of striae over the abdomen, breasts and thighs postpartum.
  
  
  RESULTS
  Of 210 women enrolled, 175 (83%) completed the study. Ninety-one women received the study lotion and 84 received the placebo. There was no difference in the development of SG (45.1% versus 48.8%; P = 0.730) or the severity of SG between cases and controls. The results did not change when presence of stretch marks at enrolment or compliance with the regimen were taken into account.
  
  
  CONCLUSIONS
  Topical application of a lotion containing cocoa butter does not appear to reduce the likelihood of developing striae gravidarum.
authors: Department of Health Behaviour and Education, American University of Beirut Medical Center, Beirut, Lebanon.
authors: H
authors: H
authors: Osman
authors: I M
authors: IM
authors: Usta
authors: N
authors: N
authors: Rubeiz
authors: R
authors: R
authors: Abu-Rustum
authors: I
authors: I
authors: Charara
authors: A H
authors: AH
authors: Nassar
mesh_terms: D000287:Administration, Topical; D000328:Adult; D003879:Dermatologic Agents / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control*; D011295:Prenatal Care; D012871:Skin Diseases / Q000517:prevention & control*
chemical_list: D003879:Dermatologic Agents; D004041:Dietary Fats; C052387:cocoa butter