The role of gamma-aminobutyric acid and its receptors in the nucleus of basal optic root in pigeons.
The effects of gamma-aminobutyric acid (GABA) and its antagonists bicuculline and 2-hydroxysaclofen on neuronal firings in the nucleus of basal optic root (nBOR) in pigeons were studied by using extracellular recording and microiontophoretic techniques. The results suggest that GABA may be an inhibitory neurotransmitter or modulator within nBOR, functioning by means of main mediation of GABA(A) receptors and of minor mediation of GABA(B) receptors. Furthermore, GABA and its GABA(A) receptors are involved in the modulation of directional selectivity in part of nBOR neurons.
Fu
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Laboratory for Visual Information Processing, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Gao
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George
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Wang
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