title: In vivo analysis of wound architecture in 700 microm microphakonit cataract surgery.
abstract: OBJECTIVE
  To analyze the clear corneal wound architecture in 700 microm cataract surgery (microphakonit) using anterior segment optical coherence tomography (AS-OCT).
  
  
  METHODS
  Dr Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
  
  
  METHODS
  Wound architecture was analyzed by AS-OCT 30 minutes after surgery and 1, 3, and 7 days postoperatively in 12 eyes (11 patients) that had microphakonit surgery. Five eyes had microphakonit with a 700 microm phaco tip with no intraocular lens (IOL) implantation, and 7 eyes had foldable IOL implantation after the main port was extended with a 2.8 mm keratome.
  
  
  RESULTS
  Twenty-four clear corneal wounds, which included the main port and the side port, were studied. The mean endothelial misalignment in the microphakonit wound was 0.085 mm +/- 0.09 (SD) immediately postoperatively, 0.057 +/- 0.07 mm at 1 day, 0.020 +/- 0.04 mm at 3 days, and 0.0 mm at 7 days. The mean coaptation loss was 0.030 +/- 0.06 mm immediately postoperatively, 0.029 +/- 0.04 mm at 1 day, and 0.029 +/- 0.04 mm at 3 days. There was a significant positive correlation between the change in stromal hydration and coaptation loss in the 17 wounds without extension; 82.3% of wounds at 3 days and 100% at 7 days had complete endothelial alignment.
  
  
  CONCLUSIONS
  Although there was no significant difference in endothelial misalignment, coaptation loss, or amount of stromal hydration between microphakonit wounds without and wounds with a 2.8 mm keratome extension, wound healing and resolution of coaptation loss or endothelial realignment occurred earlier in wounds without extension.
authors: Doctor Agarwal's Eye Hospital and Eye Research Centre, 19 Cathedral Road, Chennai, Tamil Nadu, India. dragarwal@vsnl.com
authors: Amar
authors: A
authors: Agarwal
authors: Dhivya Ashok
authors: DA
authors: Kumar
authors: Soosan
authors: S
authors: Jacob
authors: Athiya
authors: A
authors: Agarwal
mesh_terms: D003315:Cornea / Q000473:pathology* / Q000601:surgery; D003319:Corneal Stroma / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D008866:Microsurgery / Q000379:methods*; D018918:Phacoemulsification / Q000379:methods*; D041623:Tomography, Optical Coherence; D014945:Wound Healing