[The guideline 'Recurrent miscarriage' (first revision) of the Dutch Society for Obstetrics and Gynaecology].
--In 2007, the Dutch Society for Obstetrics and Gynaecology issued a revised version of the 1999 guideline on recurrent miscarriage. --The new guideline was developed according to the principles of evidence-based guideline development and includes levels of evidence. --The guideline contains recommendations for effective diagnosis and treatment and explicitly mentions certain diagnostic tests and treatments that should be avoided. --After a thorough investigation of a couples'-history, the type of diagnostic tests that should be offered to the couple can be determined. Patients with a low risk of having cytogenetic abnormalities or thrombophilia may be excluded from parental karyotyping and thrombophilia screening, respectively. --Women with confirmed antiphospholipid antibody syndrome should be offered anticoagulation treatment before and during subsequent pregnancies. --Effective therapy for unexplained recurrent miscarriage is lacking. However, the probability of a successful future pregnancy is high. This probability can be estimated based on the number of previous miscarriages and maternal age.
Goddijn
M
M
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Verloskunde en Gynaecologie, Amsterdam. m.goddijn@amc.uva.nl
van den Boogaard
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Steepers
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Erwich
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Macklon
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Land
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Ankum
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D000026:Abortion, Habitual / Q000209:etiology / Q000517:prevention & control*; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000188:drug therapy; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008423:Maternal Age; D009426:Netherlands; D009774:Obstetrics / Q000592:standards*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012307:Risk Factors; D012955:Societies, Medical
D000925:Anticoagulants