Intracellular transport: kinesins working together.
While most in vitro experiments with motor proteins focus on the behavior of individual motors, in cells most cargo are transported by multiple motors and even multiple classes of motor. How these motors cooperate and compete in transporting cargo is not clear. Recent experimental and theoretical work suggests that motors attached to a given cargo interact in both expected and unexpected ways.
Hancock
William O
WO
Department of Bioengineering, Penn State University, University Park, Pennsylvania 16802, USA. wohbio@engr.psu.edu
D001692:Biological Transport; D001696:Biomechanical Phenomena; D016547:Kinesins / Q000378:metabolism*; D008958:Models, Molecular
D016547:Kinesins