Correlation between the water drinking test and modified diurnal tension curve in untreated glaucomatous eyes.
OBJECTIVE
To investigate the correlation and agreement between the intraocular pressure peaks detected during the water drinking test and the modified diurnal tension curve in untreated glaucomatous eyes.


BACKGROUND
It has been suggested that the intraocular pressure peaks detected during the water drinking test predict the peaks observed during a 24-hour diurnal tension curve. A more feasible and practical test for assessing intraocular pressure peaks in glaucomatous eyes during office hours would be of great clinical utility.


METHODS
This was a prospective study involving open angle glaucoma patients without anti-glaucoma medication submitted to the modified diurnal tension curve and water drinking test on the same day. The intraocular pressure peaks during the water drinking test and the modified diurnal tension curve were reported and compared. Statistical analysis was performed to assess the correlation and agreement between intraocular pressure peak measurements.


RESULTS
The correlation between intraocular pressure peaks during the water drinking test and modified diurnal tension curve was significant and strong (Pearson's Correlation Coefficient r=0.780, p<0.0001). Limited agreement was observed between these measurements. Eighty-two percent of intraocular pressure peaks were higher during the water drinking test than the modified diurnal tension curve.


CONCLUSIONS
These findings suggest that the water drinking test may be used as tool to assess risk factors for glaucomatous patients.


CONCLUSIONS
Intraocular pressure peaks detected during the water drinking test could be used in clinical practice to both estimate the peaks observed during the modified diurnal tension curve and assess the status of the eye's outflow facility.
Vasconcelos-Moraes
Carlos Gustavo
CG
Glaucoma Service, Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. gustavousp@gmail.com
Susanna
Remo
R
D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology; D018450:Disease Progression; D004326:Drinking / Q000502:physiology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D011446:Prospective Studies; D014065:Tonometry, Ocular / Q000379:methods*; D014867:Water / Q000008:administration & dosage*
D014867:Water