Melasma: successful treatment with pidobenzone 4% (K5lipogel).
Melasma (a term derived from the Greek word "melas" meaning black) is an acquired blotchy, irregularly patterned, brown or sometimes gray brown hypermelanosis of the face and occasionally the neck. Its etiology is poorly understood but mainly related to sunlight and genetic predisposition. Melasma seems to be more frequent in darker skinned people, especially women. Its treatment is always difficult and the condition usually relapses. The treatment with pidobenzone 4% (K5 lipogel), twice per day for 16 weeks has proved to be safe and effective. Pidobenzone 4% lipogel, according to the present study, seems also to represent a useful, reliable, and safe treatment of the different types of melasma.
Zanieri
Fabio
F
Centro Interuniversitario di Dermatologia Biologica e Psicosomatica, Università Consorziate, Firenze-Milano-Siena, Italy.
Assad
Gelareh Bani
GB
Campolmi
Piero
P
Lotti
Torello
T
D000328:Adult; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D005782:Gels; D006801:Humans; D008548:Melanosis / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D011392:Proline / Q000031:analogs & derivatives / Q000627:therapeutic use; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult
D003879:Dermatologic Agents; D005782:Gels; D011392:Proline; C534452:pidobenzone