Development, implementation and quality assurance of biokinetic models within CONRAD.
The work of the Task Group 5.2 'Research Studies on Biokinetic Models' of the CONRAD project is presented. New biokinetic models have been implemented by several European institutions. Quality assurance procedures included intercomparison of the results as well as quality assurance of model formulation. Additionally, the use of the models was examined leading to proposals of tuning parameters. Stable isotope studies were evaluated with respect to their implications to the new models, and new biokinetic models were proposed on the basis of their results. Furthermore, the development of a biokinetic model describing the effects of decorporation of actinides by diethylenetriaminepentaacetic acid treatment was initiated.
Nosske
D
D
Federal Office for Radiation Protection, Department of Radiation Protection and Health, 85762 Oberschleissheim, Germany. dnosske@bfs.de
Birchall
A
A
Blanchardon
E
E
Breustedt
B
B
Giussani
A
A
Luciani
A
A
Oeh
U
U
Lopez
M A
MA
D008671:Actinoid Series Elements / Q000737:chemistry; D006801:Humans; D007554:Isotopes / Q000737:chemistry; D008954:Models, Biological; D004369:Pentetic Acid / Q000737:chemistry; D011786:Quality Control; D011835:Radiation Protection; D011874:Radiometry / Q000379:methods*
D008671:Actinoid Series Elements; D007554:Isotopes; D004369:Pentetic Acid