Value of myocardial regional perfusion on long-term function in collateral-dependent myocardium.
BACKGROUND
Collateral circulation is considered key for left ventricular (LV) function recovery in patients with chronic total occlusion (CTO). However, there are conflicting reports about the influence of collaterals on LV recovery after revascularization.


METHODS
Echocardiographic assessment of regional myocardial perfusion, wall motion score (WMS), and left ventricular ejection fraction (LVEF) were performed in patients with angiographically visible collateral circulation of grades 2 and 3.


RESULTS
The WMS and LVEF of group B (with presence of myocardial regional perfusion) were significantly improved at one month and six months compared to those of group A (with absence of myocardial regional perfusion). The correlation between myocardial regional blood flow and changes in WMS and LVEF was significant at 6 months in patients with angiographically visible collateral circulation of grade 2 and 3. Similar correlations were observed on myocardial contrast echocardiography (MCE) score index.


CONCLUSIONS
Myocardial function recovery in patients with CTO is determined by myocardial regional perfusion. MCE has important value for prognosis and risk stratification in patients with CTO undergoing cardiac catheterization.
Jin
Jun
J
Division of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing City, People's Republic of China. jj.xqyy@yahoo.com.cn
Huang
Lan
L
Wang
Hong
H
Song
Yao-Ming
YM
Li
Ai-Ming
AM
Qin
Jun
J
Yu
Xue-Jun
XJ
Geng
Zhao-Hua
ZH
Zhou
Xiao-Bo
XB
Zhao
Gang
G
Gao
Yun-Hua
YH
Liu
Zhen
Z
Yang
Li
L
Xia
Hong-Mei
HM
D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003097:Collateral Circulation / Q000502:physiology*; D003287:Contrast Media; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy; D004452:Echocardiography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion; D011379:Prognosis; D018570:Risk Assessment; D016277:Ventricular Function, Left / Q000502:physiology*
D003287:Contrast Media