Corneal-conjunctival squamous cell carcinoma.
OBJECTIVE
To report an extremely rare case of an extensive conjunctival-corneal invasive squamous cell carcinoma.


METHODS
A healthy 68-year-old man referred to our department with a moderately elevated hyperemic nodular mass on his right ocular surface. The lesion was completely covering the corneal surface and involved the temporal limbus with bulbar conjunctiva. Surgical excision was performed with 2-mm tumor-free margins documented histologically and double-freeze cryotherapy was applied 360 degrees for inhibition of tumor recurrence.


RESULTS
Histopathologic examination showed a moderately differentiated squamous cell carcinoma. The patient achieved a complete excision with no evidence of recurrence during the follow-up period of 12 months.


CONCLUSIONS
This case points out the potential for a total covering of the cornea by squamous cell carcinoma. Wide surgical excision and double freeze-thaw cryotherapy may decrease the recurrence.
Papaioannou
Ioannis T
IT
Department of Ophthalmology, School of Medicine, University of Patras, Patras, Greece.
Melachrinou
Maria P
MP
Drimtzias
Evaggelos G
EG
Gartaganis
Sotirios P
SP
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000601:surgery; D003316:Corneal Diseases / Q000473:pathology* / Q000601:surgery; D005134:Eye Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness