Rhodium-catalyzed asymmetric ring-opening alkynylation of azabenzonorbornadienes.
Asymmetric ring-opening alkynylation of meso-azabenzonorbornadienes with (triisopropylsilyl)acetylene giving 2-alkynyl-1-aminodihydronaphthalenes took place in high yields with high enantioselectivity in the presence of a rhodium/(R)-DTBM-segphos catalyst.
Nishimura
Takahiro
T
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp
Tsurumaki
Eiji
E
Kawamoto
Takahiro
T
Guo
Xun-Xiang
XX
Hayashi
Tamio
T