title: Quality of life of men treated for localized prostate cancer: outcomes at 6 and 12 months.
abstract: OBJECTIVE
  Treatments for early-stage prostate cancer (PCa) are highly effective; therefore, research studies that explore quality of life (QOL) issues associated with different treatments are important. The purposes of this study were to (a) examine differences among treatment groups of men treated with either radiation therapies or radical prostatectomy for PCa and (b) examine quality of life outcomes over time.
  
  
  METHODS
  We report outcomes 6 and 12 months after 159 men began treatment for PCa with either one of two types of radiation treatment (intensity-modulated radiation therapy plus high dose rate or intensity-modulated radiation therapy plus seed implantation) or radical prostatectomy.
  
  
  RESULTS
  Significant differences among groups are described. Significant predictors of QOL at 6 months included urinary, bowel, and sexual symptoms, anxiety, depression, problem-focused coping, and physiological self-efficacy. Significant predictors of QOL at 12 months were urinary and bowel symptoms, stress, depression, problem-focused coping, and physiological self-efficacy. Demographic variables, race, and living status were significant predictors of quality of life at 12 months.
  
  
  CONCLUSIONS
  Physiological symptoms and psychological symptoms were both significant predictors of QOL. The psychological factors that predicted quality of life in this study have potential for intervention and point to the next stage of the research.
authors: College of Nursing, Rutgers University, 180 University Av., Newark, NJ 07102, USA. eliselev@rutgers.edu
authors: Elise L
authors: EL
authors: Lev
authors: Lucille Sanzero
authors: LS
authors: Eller
authors: Glen
authors: G
authors: Gejerman
authors: John
authors: J
authors: Kolassa
authors: Joan
authors: J
authors: Colella
authors: Janine
authors: J
authors: Pezzino
authors: Patricia
authors: P
authors: Lane
authors: Ravi
authors: R
authors: Munver
authors: Michael
authors: M
authors: Esposito
authors: John
authors: J
authors: Sheuch
authors: Vincent
authors: V
authors: Lanteri
authors: Ihor
authors: I
authors: Sawczuk
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000523:psychology* / Q000532:radiotherapy / Q000601:surgery; D011788:Quality of Life; D020377:Self Efficacy; D013997:Time Factors