The misuse/abuse of antihistamine antiemetic medication (cyclizine) by cancer patients.
Cyclizine is an antihistamine, which is frequently used to manage nausea and vomiting in cancer patients. Antihistamines can be drugs of misuse/abuse, and the article describes four cancer patients who developed such problems after receiving parenteral cyclizine within the inpatient unit of a cancer centre. The article also briefly reviews the literature on the misuse/abuse of cyclizine and other antihistamines.
Bailey
F
F
Woking Hospice, Woking, Surrey.
Davies
A
A
D000293:Adolescent; D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use*; D003501:Cyclizine / Q000627:therapeutic use*; D005260:Female; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced*; D009369:Neoplasms / Q000188:drug therapy*; D019966:Substance-Related Disorders; D014839:Vomiting / Q000139:chemically induced*
D000932:Antiemetics; D006633:Histamine Antagonists; D003501:Cyclizine