title: Effectiveness of different cleaning agents against the colonization of Candida spp and the in vitro detection of the adherence of these yeast cells to denture acrylic surfaces.
abstract: OBJECTIVE
  The aim of this study is to examine the effect Klorhex and Fittydent, which are used as cleaning agents on the adhesion of Candida on the surfaces of acrylic denture and palatal mucosa. In addition, ability of yeasts to adhere to acrylic strips was evaluated after applying these agents in vitro.
  
  
  METHODS
  Each group of 15 patients cleaned their dentures with either Klorhex or with Fittydent. The control group cleaned their dentures with water.
  
  
  RESULTS
  It was found that 62.2% of the patients had colonies of Candida species on their palatal mucosa which was reduced to 51.1% after using these cleaning agents. The colonization rate with Candida spp on their dentures was reduces from 82.2% to 68.8% using these cleaning agents. The mean adhesion value of the Candida strains isolated from the acrylic strips were found to be 75 cell/strip prior to applying the Klorhex and Fittydent and 37.5 cell/strip and 15 cell/strip after applying these agents, respectively.
  
  
  CONCLUSIONS
  These results showed that Klorhex and Fittydent have a certain preventive effect on the colonization rate of Candida spp on the surface of these dentures, the palatal mucosa, as well as on the acrylic strips in vitro.
authors: Department of Prosthetic Dentistry, Faculty of Dentistry, University of Gazi, Ankara, Turkey. dnalbant@gazi.edu.tr
authors: A Dilek
authors: AD
authors: Nalbant
authors: Ayse
authors: A
authors: Kalkanci
authors: Banu
authors: B
authors: Filiz
authors: Semra
authors: S
authors: Kustimur
mesh_terms: D000179:Acrylates; D000268:Adhesiveness / Q000187:drug effects; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000166:cytology* / Q000187:drug effects*; D002448:Cell Adhesion / Q000187:drug effects; D003820:Denture Cleansers / Q000494:pharmacology*; D003778:Dentures; D009061:Mouth Mucosa / Q000187:drug effects / Q000382:microbiology; D011145:Polyvinyls / Q000494:pharmacology
chemical_list: D000179:Acrylates; D000935:Antifungal Agents; D003820:Denture Cleansers; C095403:Fittydent; D011145:Polyvinyls; C036658:acrylic acid