title: [Diencephalo-telencephalic changes of tyrosine hydroxylase in rats and common frogs (Rana temporaria) after sleep deprivation].
abstract: Based on sleep deprivation-produced changes of electrographic parameters of the wakefulness--sleep cycle (WSC) in rats and common frogs, dynamics of activity of tyrosine hydroxylase, the key enzyme of dopamine synthesis, was studied immunohistochemically in substantia nigra and nigrostriatal pathway in rats and in striatum, paraventricular organ, and extrahypothalamic pathways in frogs. There are revealed changes in dynamics of tyrosine hydroxylase in rats and in common frogs after the 6-h sleep deprivation and after 2 h of postdeprivation sleep. This allows determining the degree of participation of corticostriatal neuroregulatory and hypothalamo-pituitary neurosecretory systems and their role in regulation of WSC. Possible evolutionary peculiarities of morphofunctional differences in homoiothermal and poikilothermal animals are discussed.
authors: G A
authors: GA
authors: Oganesian
authors: I V
authors: IV
authors: Romanova
authors: E A
authors: EA
authors: Aristakesian
authors: V V
authors: VV
authors: Kuzik
authors: D M
authors: DM
authors: Makina
authors: T Iu
authors: TIu
authors: Morina
authors: A E
authors: AE
authors: Khramenkova
authors: I V
authors: IV
authors: Artamokhina
authors: V A
authors: VA
authors: Belova
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D007030:Hypothalamo-Hypophyseal System / Q000201:enzymology*; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011896:Rana temporaria; D051381:Rats; D017208:Rats, Wistar; D012890:Sleep; D012892:Sleep Deprivation / Q000201:enzymology*; D013687:Telencephalon / Q000201:enzymology*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*; D014851:Wakefulness
chemical_list: D009419:Nerve Tissue Proteins; D014446:Tyrosine 3-Monooxygenase