title: Cutaneous polyarteritis nodosa in a patient with Crohn's disease.
abstract: A 19-year-old Japanese woman with a 4-year history of Crohn's disease (CD) developed high fever, polyarthralgia, and painful subcutaneous nodules of the legs. A skin biopsy showed panarteritis with fibrinoid necrosis in the deep dermis. Endoscopic examination showed aphthous lesions in the entire colon. She was diagnosed with cutaneous polyarteritis nodosa (PAN) associated with CD. Steroid therapy improved her symptoms. To our knowledge, this is the first Japanese case of cutaneous PAN associated with CD.
authors: Third Department of Internal Medicine, Akita University School of Medicine, and Department of Hematology, Municipal Akita General Hospital, 1-1-1 Hondo, Akita, 010-8543, Japan. komatsud@med.akita-u.ac.jp
authors: Atsushi
authors: A
authors: Komatsuda
authors: Koji
authors: K
authors: Kinoshita
authors: Masaru
authors: M
authors: Togashi
authors: Nobuki
authors: N
authors: Maki
authors: Rie
authors: R
authors: Masai
authors: Hidetaka
authors: H
authors: Niitsu
authors: Setsuya
authors: S
authors: Ohtani
authors: Masato
authors: M
authors: Sageshima
authors: Ken-ichi
authors: K
authors: Sawada
authors: Hideki
authors: H
authors: Wakui
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D019804:Mesalamine / Q000627:therapeutic use; D009336:Necrosis / Q000150:complications / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000098:blood supply / Q000473:pathology*; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D019804:Mesalamine; D011239:Prednisolone