title: Clinical review: liberation from mechanical ventilation.
abstract: Mechanical ventilation is the defining event of intensive care unit (ICU) management. Although it is a life saving intervention in patients with acute respiratory failure and other disease entities, a major goal of critical care clinicians should be to liberate patients from mechanical ventilation as early as possible to avoid the multitude of complications and risks associated with prolonged unnecessary mechanical ventilation, including ventilator induced lung injury, ventilator associated pneumonia, increased length of ICU and hospital stay, and increased cost of care delivery. This review highlights the recent developments in assessing and testing for readiness of liberation from mechanical ventilation, the etiology of weaning failure, the value of weaning protocols, and a simple practical approach for liberation from mechanical ventilation.
authors: Department of Anesthesiology, School of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
authors: Mohamad F
authors: MF
authors: El-Khatib
authors: Pierre
authors: P
authors: Bou-Khalil
mesh_terms: D006801:Humans; D055370:Lung Injury / Q000503:physiopathology / Q000517:prevention & control; D012121:Respiration, Artificial / Q000379:methods* / Q000639:trends; D015656:Respiratory Mechanics / Q000502:physiology; D016896:Treatment Outcome; D015300:Ventilator Weaning / Q000379:methods* / Q000639:trends