An association of gastroschisis and fatal respiratory distress: does prenatal bile aspiration cause early-onset respiratory failure in neonates?
We present a neonate with gastroschisis and evidence of bile aspiration in utero, who developed severe respiratory distress that did not respond to postnatal intensive respiratory care. Although rare, a newborn with gastroschisis may develop severe respiratory distress due to bile aspiration in utero. Given the poor outcome in this case, we suggest a possible role for prenatal diagnosis and therapy.
Morikawa
Nobuyuki
N
Division of General Surgery, National Center for Child Health and Development, 2-10-1 Ookura Setagaya-ku, Tokyo 157-8535, Japan. morikawa-n@ncchd.go.jp
Honna
Toshiro
T
Kuroda
Tatsuo
T
Noya
Miki
M
Ito
Naoki
N
Nakamura
Tomoo
T
Ito
Yushi
Y
Hayashi
Satoshi
S
Sago
Haruhiko
H
Matsuoka
Kentaro
K
D001646:Bile; D017809:Fatal Outcome; D005260:Female; D020139:Gastroschisis / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007231:Infant, Newborn; D011014:Pneumonia / Q000150:complications; D011030:Pneumothorax / Q000150:complications; D011656:Pulmonary Emphysema / Q000150:complications; D053120:Respiratory Aspiration / Q000150:complications*; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications*