Paraneoplastic leukemoid reaction as marker for transitional cell carcinoma recurrence.
A case of a 78-year-old man with transitional cell carcinoma and a paraneoplastic leukemoid reaction. The leukocytosis was present at the diagnosis of carcinoma. It dissipated with complete tumor resection, was absent when a surveillance computed tomography scan showed no evidence of recurrence at 6 months, and had returned with tumor recurrence at 8 months. This case demonstrates that a paraneoplastic leukemoid reaction can be used as a tumor marker in cases of transitional cell carcinoma when a leukemoid reaction is found at presentation.
Dukes
Jonathan W
JW
Department of Medicine, University of California, San Francisco, California, USA. jonathan.dukes@jhmi.edu
Tierney
Lawrence M
LM
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007955:Leukemoid Reaction / Q000209:etiology*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000150:complications* / Q000175:diagnosis; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000175:diagnosis