title: Campylobacter sugars sticking out.
abstract: The amazing repertoire of glycoconjugates that are found in Campylobacter jejuni includes lipooligosaccharides mimicking human glycolipids, capsular polysaccharides with complex and unusual sugars, and proteins that are post-translationally modified with either O- or N-linked glycans. Thus, the glycome of this important food-borne pathogen is an excellent toolbox for glycobiologists to understand the fundamentals of these pathways and their role in host-microbe interactions, develop new techniques for glycobiology and exploit these pathways for novel diagnostics and therapeutics. The exciting surge in recent research activities will be summarized in this review.
authors: Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA.
authors: Patricia
authors: P
authors: Guerry
authors: Christine M
authors: CM
authors: Szymanski
mesh_terms: D000818:Animals; D016667:Bacterial Capsules / Q000737:chemistry / Q000378:metabolism*; D002169:Campylobacter Infections / Q000378:metabolism / Q000382:microbiology*; D016123:Campylobacter jejuni / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D005408:Flagellin / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D006031:Glycosylation; D054884:Host-Pathogen Interactions; D006801:Humans; D008070:Lipopolysaccharides / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular
chemical_list: D008070:Lipopolysaccharides; C023023:lipid-linked oligosaccharides; D005408:Flagellin