[Some aspects of the regeneration process carried out by means of pluripotent stem cells].
This work is devoted to the vital topic of regeneration by stem cells. Cells-predecessors and differentiated cells can divide a limited number of times (Alberts et al., 1994) and are not capable of providing tissue regeneration throughout the ontogenesis. The tissue renewal during such a long period is impossible without participation of a specialized system responsible for regeneration. The given system is submitted by stem cells which are capable of being differentiated in all types of somatic cells and in a line of germ cells, and also have ability to self-renew during the whole life of an organism. Results of our research suggest that stem cells make up a universal mechanism of regeneration which has been formed during evolution.
Pecherskiĭ
A V
AV
Pecherskiĭ
V I
VI
Aseev
M V
MV
Droblenkov
A V
AV
Semiglazov
V F
VF
D000293:Adolescent; D000328:Adult; D000368:Aged; D005075:Biological Evolution; D002648:Child; D005260:Female; D019254:Genes, bcl-2 / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D039902:Multipotent Stem Cells / Q000502:physiology* / Q000637:transplantation; D011944:Receptors, Androgen / Q000378:metabolism; D012038:Regeneration / Q000502:physiology*; D012867:Skin / Q000378:metabolism; D012879:Skin Physiological Phenomena; D013739:Testosterone / Q000502:physiology
D011944:Receptors, Androgen; D013739:Testosterone