[Calcium homeostasis and nitric oxide processes in children with migraine].
Eighty-one children aged 6 to 17 years who had migraine were examined by clinical and biochemical studies. The activity of Ca2(+)-ATPase and the levels of total intracellular calcium of platelets and plasma nitrites were studied in the attack-free period. Children with migraine were fond to have elevated levels of stable nitric oxide metabolites (nitrites). The level of intracellular calcium was 2 times greater than that in healthy children of the same age, which was followed by compensatory Ca2(+)-ATPase activation. There was a relationship of the parameters of calcium homeostasis and the plasma level of nitrites to the clinical and pathogenetic manifestations of migraine.
Rakhmanina
O A
OA
Levitina
E V
EV
Zhuravleva
T D
TD
D000293:Adolescent; D002118:Calcium / Q000097:blood*; D000252:Calcium-Transporting ATPases / Q000097:blood; D002648:Child; D005260:Female; D006706:Homeostasis; D006801:Humans; D042541:Intracellular Space / Q000378:metabolism; D008297:Male; D008881:Migraine Disorders / Q000378:metabolism*; D020325:Migraine with Aura / Q000378:metabolism; D020326:Migraine without Aura / Q000378:metabolism; D009569:Nitric Oxide / Q000097:blood*
D009569:Nitric Oxide; D000252:Calcium-Transporting ATPases; D002118:Calcium