The volume-activated chloride current depends on phospholipase C activation and intracellular calcium mobilization.
Varela
D
D
Centro de Estudios Moleculares de la Célula & Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, Santiago-6530499, Santiago-Chile. dvarela@bitmed.med.uchile.cl
Simon
F
F
Riveros
A
A
Jørgensen
F
F
Stutzin
A
A
D002118:Calcium / Q000494:pharmacology; D020013:Calcium Signaling / Q000187:drug effects; D002460:Cell Line; D048429:Cell Size / Q000187:drug effects; D018118:Chloride Channels / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D007038:Hypotonic Solutions; D053496:Inositol 1,4,5-Trisphosphate Receptors / Q000037:antagonists & inhibitors; D042541:Intracellular Space / Q000187:drug effects / Q000378:metabolism*; D015640:Ion Channel Gating / Q000187:drug effects; D013997:Time Factors; D010738:Type C Phospholipases / Q000037:antagonists & inhibitors / Q000378:metabolism*
D018118:Chloride Channels; D004791:Enzyme Inhibitors; D007038:Hypotonic Solutions; D053496:Inositol 1,4,5-Trisphosphate Receptors; D010738:Type C Phospholipases; D002118:Calcium