title: Visual outcomes after wavefront-guided laser in situ keratomileusis with and without iris registration.
abstract: OBJECTIVE
  To compare the clinical outcomes of wavefront-guided laser in situ keratomileusis in eyes in which iris registration was used (IR group) and eyes in which iris registration would not engage (no-IR group).
  
  
  METHODS
  Shiley Eye Center, University of California San Diego, La Jolla, California, USA.
  
  
  METHODS
  This retrospective analysis comprised 112 eyes of 64 patients who had wavefront-guided LASIK using the Visx CustomVue S4 IR platform (Advanced Medical Optics) for myopia or myopic astigmatism. The safety, efficacy, predictability, and need for enhancement at the 3-month follow-up were evaluated and compared between the IR group and the no-IR group.
  
  
  RESULTS
  By 3 months postoperatively, all eyes in the IR group and 93% of eyes in the no-IR group had the same best spectacle-corrected visual acuity (BSCVA) as preoperatively or had gained 1 to 2 lines of BSCVA. No eye in either group lost more than 1 line of BSCVA (P = 0.12). Ninety-six percent of eyes in the IR group and 93% in the no-IR group were within +/-0.50 diopter (D) of the postoperative manifest refraction spherical equivalent (P = 0.24), and all eyes were within +/-1.00 D of emmetropia. Four eyes in the IR group and 11 in the no-IR group required retreatment during the follow-up period (P = 0.1).
  
  
  CONCLUSIONS
  The results in the IR group and the no-IR group were comparable, with no statistically significant differences in measured outcomes.
authors: Shiley Eye Center, University of California-San Diego, 9415 Campus Point Drive, La Jolla, CA 92093, USA.
authors: Theeratep
authors: T
authors: Tantayakom
authors: Janice N
authors: JN
authors: Lim
authors: Tracy L
authors: TL
authors: Purcell
authors: Aniruddha
authors: A
authors: Nalgirkar
authors: Lingyun
authors: L
authors: Cheng
authors: David J
authors: DJ
authors: Schanzlin
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007498:Iris / Q000033:anatomy & histology; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D011680:Pupil; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*