title: Hygiene interventions for prevention of cytomegalovirus infection among childbearing women: systematic review.
abstract: OBJECTIVE
  This paper is a report of a systematic review to examine the effectiveness of preventive interventions to reduce congenital cytomegalovirus transmission and infection among women of childbearing age.
  
  
  BACKGROUND
  Congenital cytomegalovirus has been identified as the leading infectious cause of damage to the growing fetus in developed countries, including Down syndrome, fetal alcohol syndrome and spina bifida. Despite the prevalence and consequences of this infection, it has a low profile and pregnant mothers are often unaware of the risks and protective behaviours related to its transmission. Women with children in daycare and nurses working with children are particularly at risk of acquiring the virus.
  
  
  METHODS
  A computerized literature search for articles up to 1 December 2007 was performed using MEDLINE (from 1950); EMBASE (from 1980) and CINAHL (from 1982).
  
  
  METHODS
  Both authors independently reviewed studies that met inclusion criteria and assigned a quality rating determined by the number of validity criteria met. Differences were discussed until consensus was reached.
  
  
  RESULTS
  Differences in hygiene behaviour changes were most statistically significant for pregnant, seronegative women. Although the methodological quality of the three included studies was not strong, seroconversion rates consistently decreased as cytomegalovirus education and support increased.
  
  
  CONCLUSIONS
  Nurses can act as preventive agents for cytomegalovirus infection through education about hygiene precautions during antenatal care and through preventive measures in the workplace. The review findings suggest educational interventions in hygiene practices have the potential to be a feasible, large-scale, primary prevention strategy.
authors: University of Toronto, Ontario, Canada. jessharvey@cogeco.ca
authors: Jessica
authors: J
authors: Harvey
authors: Cindy-Lee
authors: CL
authors: Dennis
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000451:nursing / Q000517:prevention & control* / Q000635:transmission; D004506:Education, Nursing; D005260:Female; D006801:Humans; D006920:Hygiene; D016273:Occupational Exposure / Q000009:adverse effects; D010353:Patient Education as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000451:nursing / Q000517:prevention & control*; D011322:Primary Prevention / Q000379:methods*