title: Evaluation of an electron Monte Carlo dose calculation algorithm for electron beam.
abstract: The electron Monte Carlo (eMC) dose calculation algorithm of the Eclipse treatment planning system is based heavily upon Monte Carlo simulation of the linac head and modeling of the linac beam characteristics with minimal measurement of beam data. Commissioning of the eMC algorithm on multiple identical linacs provided a unique opportunity to systematically evaluate the algorithm with actual measurements of clinically relevant beam and dose parameters. In this study, measured and eMC calculated dose distributions were compared both along and perpendicular to electron beam direction for electron energy/applicator/depth combination using measurement data from four Varian 21EX CLINAC linear accelerator (Varian Medical System, Palo Alto, CA). Cutout factors for sizes down to 3 x 3 cm were also compared. Comparisons between the measurement and the eMC calculated values show that the R90, R80, R50, and R10 values mostly agree within 3 mm. Measure and Calculated bremsstrahlung dose Dx correlates well statistically although eMC calculated Dx values are consistently smaller than the measured, with maximum discrepancy of 1% for the 20 MeV electron beams. Surface dose agrees mostly within 2%. Field width and penumbra agree mostly within 3mm. Calculation grid size is found to have a significant effect on the dose calculation. A grid size of 5 mm can produce erroneous dose distributions. Using a grid size of 2.5 mm and a 3% accuracy specified for the eMC to stop calculation iteration, the absolute output agrees with measurements within 3% for field sizes of 5 x 5 cm or larger. For cutout of 3 x 3 cm, however, the output disagreement can reach 8%. Our result indicate that eMC algorithm in Eclipse provides acceptable agreement with measurement data for most clinical situations. Calculation grid size of 2.5 mm or smaller is recommended.
authors: Department of Radiation Oncology, University of Colorado Health Science Center, Aurora, CO.
authors: Ye Angela
authors: YA
authors: Hu
authors: Department of Radiation Oncology, Duke University Medical Center, Durham, NC.
authors: Haijun
authors: H
authors: Song
authors: Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
authors: Zhe
authors: Z
authors: Chen
authors: Department of Radiation Oncology, Duke University Medical Center, Durham, NC.
authors: Sumin
authors: S
authors: Zhou
authors: Department of Radiation Oncology, Duke University Medical Center, Durham, NC.
authors: Fang-Fang
authors: FF
authors: Yin
mesh_terms: D000465:Algorithms; D004583:Electrons / Q000627:therapeutic use*; D009010:Monte Carlo Method; D010315:Particle Accelerators; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods