Acute type II cryoglobulinaemic vasculitis mimicking atherosclerotic peripheral vascular disease.
Atherosclerotic peripheral vascular disease is a common presenting cause for digital ischaemia in life long smokers. Acute severe Type II Cryoglobulinaemic vasculitis is a rare yet important cause, which may present with similar clinical features and which if undiagnosed may be rapidly fatal. Following the instigation of therapy with intravenous methylprednisolone and cyclophosphamide this patient made an excellent recovery.
Saeed
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Mid Western Regional Hospital, Limerick, Ireland. modelian@gmail.com
Khan
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Irwin
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Fraser
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D000368:Aged; D050197:Atherosclerosis / Q000175:diagnosis*; D003449:Cryoglobulinemia / Q000150:complications*; D011464:Epoprostenol / Q000008:administration & dosage; D005260:Female; D005385:Fingers / Q000098:blood supply; D006365:Heel; D006801:Humans; D007511:Ischemia / Q000503:physiopathology; D008775:Methylprednisolone / Q000008:administration & dosage; D009336:Necrosis; D020551:Pulse Therapy, Drug; D012039:Regional Blood Flow; D012883:Skin Ulcer / Q000188:drug therapy / Q000473:pathology* / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects; D014657:Vasculitis / Q000175:diagnosis* / Q000188:drug therapy
D011464:Epoprostenol; D008775:Methylprednisolone