title: [Intraocular hemorrhage in a goat with thrombocytopenia and metastasis of an adenocarcinoma in the iris].
abstract: This case report describes the findings in a 10-year-old goat with metastasis of an adenocarcinoma in the iris. Two weeks before admission, the owner had noticed blepharospasm of the left eye. Clinical examination by the referring veterinarian revealed unilateral intraocular hemorrhage. The goat was referred to our clinic for further work-up. The rectal temperature was 40 degrees C. The most important haematological result was severe thrombocytopenia. There was mild corneal oedema of the left eye. Approximately 75 per cent of the anterior chamber was filled with non-coagulated blood. The fluid in the anterior chamber dorsal to the blood was cloudy, and the corpora nigra could not be seen clearly. All other internal parts of the eye could not be seen. Ultrasonography of the left eye confirmed cloudiness of the anterior chamber and revealed moderate thickening of the iris. The right prescapular lymph node was markedly enlarged. Cytological examination of a fine needle aspirate of the lymph node showed a mixed population of neoplastic cells. Based on immunohistochemical evaluation of the cells metastasis of a carcinoma was diagnosed. The goat was subjected to euthanasia, and a postmortem examination was carried out. The anterior chamber of the left eye contained blood, and the iris was thicker than normal and adhered to the posterior surface of the cornea. There were neoplastic alterations in the iris, the oesophagus, the lung lobes, the liver, the kidney and in the prescapular, retropharyngeal, mediastinal and hepatic lymph nodes. Histologically, a diagnosis of carcinoma was confirmed, but the origin of the tumour could not be determined.
authors: Departement für Nutztiere der Universität Zürich. ubraun@vetclinics.uzh.ch
authors: U
authors: U
authors: Braun
authors: P
authors: P
authors: Grest
authors: W
authors: W
authors: Jehle
authors: S
authors: S
authors: Kaps
authors: B
authors: B
authors: Spiess
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D000818:Animals; D005130:Eye Hemorrhage / Q000209:etiology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D015511:Goat Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006041:Goats; D015811:Iris Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D013921:Thrombocytopenia / Q000209:etiology / Q000662:veterinary