title: [Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis].
abstract: OBJECTIVE
  To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.
  
  
  METHODS
  Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.
  
  
  RESULTS
  The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P < 0.01).
  
  
  CONCLUSIONS
  MBP was involved in the formation of CRS.
authors: Department of Otorhinolaryngology Head and Neck Surgery, Tongren Hospital, Capital University of Medical Science, Beijing 100073, China.
authors: Jing
authors: J
authors: Hou
authors: Bing
authors: B
authors: Zhou
authors: Luo
authors: L
authors: Zhang
authors: Yunchuan
authors: Y
authors: Li
authors: Ming
authors: M
authors: Liu
authors: Yongxiang
authors: Y
authors: Wei
authors: Qian
authors: Q
authors: Huang
authors: Yang
authors: Y
authors: Wang
mesh_terms: D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D016022:Case-Control Studies; D002908:Chronic Disease; D047093:Eosinophil Major Basic Protein; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000378:metabolism*; D009297:Nasal Mucosa / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism*; D012852:Sinusitis / Q000378:metabolism* / Q000473:pathology
chemical_list: D001798:Blood Proteins; D011509:Proteoglycans; C074129:PRG2 protein, human; D047093:Eosinophil Major Basic Protein