Platinum- and gold-catalyzed hydrative carbocyclization of oxo diynes for one-pot synthesis of benzopyrones and bicyclic spiro ketones.
We report a one-pot synthesis of benzopyrones and tricyclic spiroketones from hydrative carbocyclization of oxodiyne substrates catalyzed by PtCl2 and PPh3AuCl/AgOTf, respectively. The distinct carbocyclizations with Pt and Au catalysts stem from their altered regioselectivity in the oxo-assisted hydration of the neighboring alkyne carbons.
Das
Arindam
A
Department of Chemistry, National Tsing-Hua University, Hsinchu, Taiwan, ROC.
Chang
Hsu-Kai
HK
Yang
Cheng-Hua
CH
Liu
Rai-Shung
RS