Visualization of age-dependent myocardial metabolic impairment in cardiomyopathic model hamster obtained by fluorescent X-ray computed tomography using I-127 BMIPP.
Fluorescent X-ray computed tomography (FXCT) enables visualization of myocardial fatty acid metabolism by using non-radio-iodinated I-5-(p-iodophenyl)-3-(R,S)-methylpentadecanoice acid (BMIPP). In this experiment, age-dependent myocardial metabolic impairment was successfully imaged and analyzed quantitatively in J2N-k cardiomyopathic hamster using FXCT.
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan.
Takeda
Tohoru
T
Wu
Jin
J
Huo
Qingkai
Q
Yuasa
Tetsuya
T
Hyodo
Kazuyuki
K
Akatsuka
Takao
T
D000375:Aging; D000818:Animals; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000378:metabolism; D006224:Cricetinae; D005227:Fatty Acids; D005453:Fluorescence; D006321:Heart / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D009206:Myocardium / Q000378:metabolism*; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed / Q000379:methods
D005227:Fatty Acids; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; C049338:iodofiltic acid