title: Cutaneous leishmaniasis caused by Leishmania tropica in Algeria.
abstract: Cutaneous leishmaniasis is endemic in Algeria, but clinical and parasitological data from this area are scarce. In order to document the transmission of this disease in a peri-urban setting, cutaneous lesions from patients living in Constantine City and surrounding areas were spotted on filter paper for diagnosis and species identification using real-time PCR. Surprisingly, Leishmania tropica was detected in 6/69 patients, and confirmation was obtained by sequencing. This observation suggests a modification of the epidemiology of cutaneous leishmaniasis in Algeria and should alert physicians and policy-makers to the risk of antimony treatment failure with this species.
authors: Laboratoire de Biosynthèse et Ecologie des Arthropodes, Faculté des Sciences de la Nature et de la Vie, Université Mentouri, Constantine, Algérie.
authors: Ilhem
authors: I
authors: Mihoubi
authors: Stéphane
authors: S
authors: Picot
authors: Nadia
authors: N
authors: Hafirassou
authors: Frédérique
authors: F
authors: de Monbrison
mesh_terms: D000462:Algeria; D000818:Animals; D016054:DNA, Protozoan / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D007895:Leishmania tropica / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000469:parasitology*; D016133:Polymerase Chain Reaction / Q000379:methods; D012423:Rural Health; D014504:Urban Health
chemical_list: D016054:DNA, Protozoan