Prenatal diagnosis and management of fetal Long QT syndrome.
This report describes a fetus presenting with second-degree atrioventricular block, sinus bradycardia, and transient ventricular tachycardia with ventriculoatrial dissociation. Long QT syndrome (LQTS) was suspected due to the association of heart rhythm disturbances and very short transmitral early deceleration time. This impaired relaxation of the left ventricle was explained by the extreme prolongation of the refractory period caused by the prolonged relaxation time. The infant was treated successfully with beta-blockers and implantation of a pacemaker. The prognosis is poor when LQTS presents utero or during the first week of life. To date, only a few case reports of a fetus with LQTS have been published.
Tomek
Viktor
V
Kardiocentrum and Cardiovascular Research Centre, University Hospital Motol, V uvalu 84, 150 08, Prague 5, Czech Republic. viktor.tomek@seznam.cz
Skovranek
Jan
J
Gebauer
Roman A
RA
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D002304:Cardiac Pacing, Artificial; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy; D008297:Male; D014290:Metipranolol / Q000627:therapeutic use; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014288:Trimecaine / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D000889:Anti-Arrhythmia Agents; D014288:Trimecaine; D014290:Metipranolol