Relationship between central corneal thickness and hypotony-related complications after glaucoma surgery.
OBJECTIVE
To examine the hypothesis that patients with increased central corneal thickness may have an overestimation of Goldmann applanation tension and a predisposition to hypotony-related complications.


METHODS
A case-control analysis of patients with an intraocular pressure of 7 mm Hg or less on two consecutive postoperative visits following glaucoma filtration or drainage implant surgery was performed. Forward stepwise multiple logistic regression was used to determine the model that best predicted hypotony-related complications defined as choroidal effusion or hypotony maculopathy.


RESULTS
Forty-three eyes (17 with hypotony-related complications and 26 controls) of 43 patients were enrolled. Eyes with pseudophakia (P = .006) and lower postoperative intraocular pressure (P = .013) were significantly more likely to develop hypotony-related complications. Mean central corneal thickness was similar in eyes with hypotony-related complications (519 +/- 32 microm) and controls (525 +/- 37 microm) and was not a significant predictor of hypotony-related complications in the multivariate model (P = .90).


CONCLUSIONS
Increased central corneal thickness does not represent a risk factor for hypotony-related complications following glaucoma surgery.
Wellik
Sarah R
SR
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, FL 33418, USA.
Schiffman
Joyce C
JC
Budenz
Donald L
DL
Greenfield
David S
DS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001837:Body Weights and Measures; D016022:Case-Control Studies; D015862:Choroid Diseases / Q000209:etiology; D003315:Cornea / Q000473:pathology*; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D015814:Ocular Hypotension / Q000209:etiology*; D011183:Postoperative Complications; D012164:Retinal Diseases / Q000209:etiology; D012307:Risk Factors; D014065:Tonometry, Ocular; D014130:Trabeculectomy