title: Management of necrotizing pancreatitis in the third trimester of pregnancy.
abstract: BACKGROUND
  Acute pancreatitis during pregnancy is a severe disease with a high materno-fetal mortality, which recently decreased because of earlier diagnosis and improvement in maternal and neonatal intensive care.
  
  
  METHODS
  We describe a 19-year-old woman who presented at 37 weeks gestation with acute abdominal pain and attacks of vomiting. Obstetrical and fetal examinations were normal. Biochemical investigations and magnetic resonance imaging showed a gallstone migration with necrotizing pancreatitis (Balthazar 5 points). Our multidisciplinary team decided on nonsurgical conservative treatment including morphine administration and enteral feeding, and vaginal delivery which was possible 30 h after induction of labor. Follow up was uneventful with a resolution of pain and signs of pancreatitis on imaging.
  
  
  CONCLUSIONS
  Magnetic resonance imaging can be useful and safe to estimate the severity of acute and necrotizing pancreatitis in the third trimester of pregnancy. In case of sterile necrotizing pancreatitis, nonsurgical conservative treatment and a vaginal delivery should be performed when possible in these patients to reduce the risk of maternal infection.
authors: Department of Obstetrics and Gynecology, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Université Paris 7, 100, Boulevard du Général Leclerc, 92110 Clichy, France. g.ducarme@gmail.com
authors: Guillaume
authors: G
authors: Ducarme
authors: Paul
authors: P
authors: Châtel
authors: Arnaud
authors: A
authors: Alves
authors: Pascal
authors: P
authors: Hammel
authors: Dominique
authors: D
authors: Luton
mesh_terms: D000701:Analgesics, Opioid; D036861:Delivery, Obstetric; D004750:Enteral Nutrition; D005260:Female; D042882:Gallstones / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009020:Morphine; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D055815:Young Adult
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine