[Studies on chemical constituents from herbs of Taraxacum mongolicum].
OBJECTIVE
To investigate the chemical constituents of the herbs of Taraxacum mongolicum.


METHODS
The chemical constituents were isolated by various column chromatographic methods and their structures elucidated mainly by NMR and MS evidences.


RESULTS
Forty-four components were obtained and identified were as artemetin (1), quercetin (2), quercetin-3', 4', 7-trime-thyl ether (3), luteolin (4), luteolin-7-O-beta-D-glucopyranoside (5), luteolin-7-O-beta-D-galactopyranoside (6), genkwanin (7), isoetin (8), hesperetin (9), genkwanin-4'-O-beta-D-lutinoside (10), hesperidin (11), quercetin-7-O-[beta-D-glucopyranosyl (1-->6) -beta-D-glucopyranoside (12), quercetin-3, 7-O-beta-D-diglucopyranoside (13), isoetin-7-O-beta-D-glucopyranosyl- 2'-O-alpha-L-arabinopyranoside (14), isoetin-7-O-beta-D-glucopyranosyl-2'-O-alpha-D-glucopyranoside (15), isoetin-7- O-beta-D-glucopyranosyl-2'-O-beta-D-xyloypyranoside (16), caffeic acid (17), furulic acid (18), 3-O-caffeoylquinic acid (19), 3, 5-di-O-caffeoylquinic acid (20), 3, 4-di-O-caffeoylquinic acid (21), 4, 5-di-O-caffeoylquinic acid (22), 1-hydroxymethyl-5-hydroxy-phenyl-2-O-beta-D-glucopyranoside (23), p-hydroxybenzoic acid (24), p-coumaric acid (25), 3, 5-dihydroxylbenzoic acid (26), gallic acid (27), gallicin (28), syringic acid (29), 3, 4-dihydroxybenzoic acid (30), caffeic acid ethyl ester (31), esculetin (32), rufescidride (33), mongolicumin A [6, 9, 10-trihydroxy-benzoxanthene-1, 2-dicarboxylic acid] (34), mongolicumin B [1 l-hydroxy-2-oxo-guaia-1 (10), 3, 5-trien-8, 12-lactone] (35), isodonsesquitin A (36), taraxacin (37), sesquiterpene ketolactone (38), taraxasteryl acetate (39), phi-taraxasteryl acetate (40) and lupenol acetate (41), palmitic acid (42), beta-sitosterol (43), and stigmasterol (44).


CONCLUSIONS
Four compounds (14, 15, 34 and 35) were new compounds, compounds 1, 3, 6-13, 20-22, 30 and 31 were isolated from this genus for the first time, while compounds 18, 23-29, 32 and 37-42 were obtained from this species for the first time.
Shi
Shu-Yun
SY
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zhou
Chang-Xin
CX
Xu
Yan
Y
Tao
Qiao-Feng
QF
Bai
Hua
H
Lu
Fu-Sheng
FS
Lin
Wen-Yan
WY
Chen
Hai-Yong
HY
Zheng
Wei
W
Wang
Li-Wei
LW
Wu
Yi-Hang
YH
Zeng
Su
S
Huang
Ke-Xin
KX
Zhao
Yu
Y
Li
Xiao-Kun
XK
Qu
Jia
J
D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D044948:Flavonols / Q000737:chemistry; D013058:Mass Spectrometry; D031205:Taraxacum / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D044948:Flavonols