title: [Peculiarities of leukotrienes metabolism in vitamin E deficiency in rats].
abstract: Some changes take place in the spectrum of fatty acid, cholesterol and individual phospholipids' composition in the rat liver, under E-hypovitaminosis, that can play a considerable role in the cell damage. The level of cysteinyl leucotriene decreases in the blood and liver under E-hypovitaminosis and it rises to the control level under vitamin E correction. This demonstrates the influence of tocopherol on 5-LO pathway arachidonic acid.
authors: S B
authors: SB
authors: Silonov
authors: H V
authors: HV
authors: Donchenko
authors: R P
authors: RP
authors: Morozova
mesh_terms: D000818:Animals; D015289:Leukotrienes / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D024505:Tocopherols / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014811:Vitamin E Deficiency / Q000097:blood / Q000188:drug therapy / Q000378:metabolism*
chemical_list: D015289:Leukotrienes; D024505:Tocopherols