An asymptomatic case of pulmonary cryptococcosis with endobronchial polypoid lesions and bilateral infiltrative shadow.
A case of pulmonary cryptococcosis with focal endobronchial polypoid lesions is described. A 64-year-old woman consulted our hospital for further evaluation of an abnormal shadow on a chest radiograph. She had been prescribed corticosteroid for rheumatoid arthritis. Chest radiographs revealed an infiltrative shadow in the right lower and left middle and lower lung fields, and chest computed tomography (CT) revealed bilateral airspace consolidations and multiple nodules. A bronchoscopic finding revealed white polypoid lesions at the orifice of the posterior basal bronchus in the left lower lobe. Histopathological examination of transbronchial biopsy specimens demonstrated cryptococcal organisms. After fluconazole therapy for 4 months, the infiltrate had decreased in size and the bronchial polypoid lesions had disappeared.
Shimizu
Hiroki
H
Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan.
Miyashita
Naoyuki
N
Obase
Yasushi
Y
Sugiu
Tadaaki
T
Ohue
Yoshihiro
Y
Mouri
Keiji
K
Yagi
Shin-ichi
S
Kobashi
Yoshihiro
Y
Oka
Mikio
M
D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001999:Bronchoscopy; D003453:Cryptococcosis / Q000000981:diagnostic imaging* / Q000276:immunology / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000276:immunology / Q000473:pathology; D008875:Middle Aged; D011239:Prednisolone / Q000009:adverse effects*; D011859:Radiography
D005938:Glucocorticoids; D011239:Prednisolone