title: [Effect of ectopic excitation on the ventricular pump function in chicken].
abstract: The pump function of the heart ventricles was studied in chest-open anaesthetized adult female chickens under sinus rhythm and ectopic excitation of different localization. The intraventricular pressure in the right and left heart ventricles was measured by insertion of catheters through the ventricular free walls. Maximum systolic pressure, end-diastolic pressure, contractility (dP/dtmax) and relaxation (dP/dtmin) of both heart ventricles, and duration of the asynchronous contraction time of the left ventricle were analyzed. It was revealed that reduction of the pump function of the left ventricle tends to be greater under right ventricular ectopic excitation compared with left ventricular one. In comparison with the sinus rhythm, the pump function of the right ventricle was preserved to a greater extent under stimulation of the left ventricular apex and was significantly impaired under right ventricular ectopic excitation. Relaxation of both heart ventricles was more susceptible to ventricular ectopic excitation than contractility, and was more vulnerable in the right ventricle than in the left one. The direction of changes of the pump function of the heart ventricles in chickens under ventricular ectopic excitation was similar to changes of the pump function of mammalian hearts.
authors: S N
authors: SN
authors: Kharin
authors: N A
authors: NA
authors: Kibler
authors: D N
authors: DN
authors: Shmakov
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002645:Chickens; D003971:Diastole; D004558:Electric Stimulation; D005260:Female; D006321:Heart / Q000502:physiology*; D009200:Myocardial Contraction; D013599:Systole; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right