Orbital meningioma after cranial radiation for acute lymphocytic leukemia.
OBJECTIVE
To describe the ophthalmic findings of cranial radiation-induced orbital meningioma after acute lymphocytic leukemia therapy.


METHODS
This is a prospective clinical report.


RESULTS
We describe two patients recently evaluated with orbital meningiomas many years after cranial radiation for acute lymphocytic leukemia.


CONCLUSIONS
There will probably be more of these cases in the next several years. Unlike primary meningiomas, these neoplasms have a tendency to be more diffuse, multiple, and may undergo malignant degeneration.
Char
Devron H
DH
The Tumori Foundation, San Francisco, CA, USA.
Shiel
Matthew J
MJ
D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy*; D016371:Cranial Irradiation / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000532:radiotherapy*