title: Assessment and reproducibility of aortic atherosclerosis magnetic resonance imaging: impact of 3-Tesla field strength and parallel imaging.
abstract: OBJECTIVE
  To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T.
  
  
  METHODS
  Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients with impaired cardiac function) underwent 4 black-blood T2-weighted imaging studies of the abdominal aorta: 2 conventional studies at 1.5 T, a conventional study at 3 T, and an accelerated 3-T study with parallel imaging (SENSE). Contrast-to-noise ratio and image quality score (1-5 scale, 5 = highest quality) were determined for each study. Studies were analyzed for mean wall thickness and area plaque burden as endpoints for aortic atherosclerosis. Bland-Altman analyses were performed to determine interstudy reproducibility between imaging methods. Wilcoxon signed-rank tests were used to identify significant differences between methods (P < 0.05).
  
  
  RESULTS
  Image quality scores were comparable between 1.5 T and 3 T with SENSE (4.0 +/- 0.6 vs. 4.2 +/- 0.6, P = 0.21). Bland-Altman reproducibility for mean wall thickness was -0.03 mm +/- 0.15 (1.5 T vs. 1.5 T), 0.01 mm +/- 0.17 (1.5 T vs. 3 T without SENSE), and -0.01 mm +/- 0.18 (1.5 T vs. 3 T with SENSE), P = 0.83. Detection of the presence or absence of plaque was comparable. Bland-Altman reproducibility for area plaque burden was -0.02% +/- 0.32% (1.5 T vs. 1.5 T), 0.06% +/- 0.41% (1.5 T vs. 3 T without SENSE), and 0.11% +/- 0.33% (1.5 T vs. 3 T with SENSE), P = 0.41.
  
  
  CONCLUSIONS
  Black-blood MR imaging of aortic atherosclerosis is very reproducible. Parallel imaging at 3 T permits shorter scan time compared with conventional 1.5-T imaging with comparable measures of atherosclerosis extent.
authors: Department of Radiology, Division of Cardiology, Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8896, USA.
authors: Christopher D
authors: CD
authors: Maroules
authors: Roderick
authors: R
authors: McColl
authors: Amit
authors: A
authors: Khera
authors: Ronald M
authors: RM
authors: Peshock
mesh_terms: D001012:Aorta, Abdominal / Q000473:pathology*; D001018:Aortic Diseases / Q000175:diagnosis*; D050197:Atherosclerosis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity