title: Combining objective and subjective outcomes in cancer-related fatigue: illustrations from a single case report.
abstract: Neurophysiologic measurements were made on a patient with multiple lung cancers and severe cancer-related fatigue (CRF) who responded to 5 mg methylphenidate twice daily, titrated to 10 mg twice daily after 2 weeks. She remained at 10 mg twice daily for 8 months. Improvement in severe CRF (Brief Fatigue Inventory score) was associated with normalization of neurophysiologic tests.
authors: The Harry R. Horvitz Center for Palliative Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
authors: Dilara Seyidova
authors: DS
authors: Khoshknabi
authors: Mellar P
authors: MP
authors: Davis
authors: Vinoth K
authors: VK
authors: Ranganathan
authors: Vlodek
authors: V
authors: Siemionow
authors: Declan
authors: D
authors: Walsh
authors: Jordanka
authors: J
authors: Kirkova
authors: Guang H
authors: GH
authors: Yue
mesh_terms: D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D005221:Fatigue / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008774:Methylphenidate / Q000627:therapeutic use*; D008875:Middle Aged; D009460:Neurologic Examination / Q000379:methods
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate