title: [Folic acid fortification of bread recommendable].
abstract: Folic acid supplementation was recommended in the Netherlands after it had been demonstrated that periconceptional use of folic acid protected against foetal neural tube defects; this recommendation led to a slight decrease in prevalence only. According to the Dutch Health Council, fortification of bread should now be considered. Policy-making is complicated by uncertainties regarding potential side effects, such as adverse effects in children, for which scientific evidence is lacking however.
authors: VU Medisch Centrum, afd. Klinische Genetica, sectie Community Genetics/EMGO Instituut, Amsterdam. mc.cornel@vumc.nl
authors: M C
authors: MC
authors: Cornel
authors: D J
authors: DJ
authors: de Smit
authors: L T W
authors: LT
authors: de Jong-van den Berg
mesh_terms: D004305:Dose-Response Relationship, Drug; D005492:Folic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D005494:Folic Acid Deficiency / Q000150:complications / Q000517:prevention & control*; D005527:Food, Fortified; D006801:Humans; D009426:Netherlands; D009436:Neural Tube Defects / Q000453:epidemiology / Q000517:prevention & control*; D009751:Nutritional Requirements; D011322:Primary Prevention; D014803:Vitamin B Complex / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D014803:Vitamin B Complex; D005492:Folic Acid