A case report of venous thrombosis in a leprosy patient treated with corticosteroid and thalidomide.
Thalidomide is the drug of choice in the treatment of severe erythema nodosum leprosum (ENL) in men. It has recently been associated with deep venous thrombosis (DVT) when used in treatment of refractory multiple myeloma along with combination chemotherapy. We report a case of DVT in a patient treated for ENL with corticosteroids and thalidomide, and suggest a possible mechanism for the association.
Vetrichevvel
Thirthar Palanivelu
TP
Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Pise
Gajanan A
GA
Thappa
Devinder Mohan
DM
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D004893:Erythema Nodosum / Q000188:drug therapy*; D006801:Humans; D015440:Leprosy, Lepromatous / Q000150:complications*; D008297:Male; D013792:Thalidomide / Q000009:adverse effects / Q000627:therapeutic use*; D020246:Venous Thrombosis / Q000188:drug therapy*
D000305:Adrenal Cortex Hormones; D013792:Thalidomide