Wilms' tumor gene 1 (WT1) overexpression in neurons in deep endometriosis: a pilot study.
Innervation of deep endometriosis has recently been linked to its severe pain symptoms. We demonstrated for the first time that the Wilms' tumor gene 1 is overexpressed in part of these nerves.
Coosemans
An
A
Department of Obstetrics and Gynaecology, Experimental Laboratory of Gynaecology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium.
Moerman
Philippe
P
Vergote
Ignace
I
Koninckx
Philippe R
PR
Van Gool
Stefaan W
SW
Amant
Frédéric
F
D004715:Endometriosis / Q000378:metabolism* / Q000473:pathology; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology*; D016162:Genes, Wilms Tumor / Q000502:physiology*; D006801:Humans; D020932:Nerve Growth Factor / Q000378:metabolism; D009474:Neurons / Q000378:metabolism* / Q000473:pathology; D010865:Pilot Projects; D020917:Receptor, trkA / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D025721:WT1 Proteins / Q000235:genetics / Q000378:metabolism*; D019061:src-Family Kinases / Q000378:metabolism
D009418:S100 Proteins; D025721:WT1 Proteins; D020932:Nerve Growth Factor; D020917:Receptor, trkA; D019061:src-Family Kinases