Enniatins produced by Fusarium dimerum, an endophytic fungal strain.
Cyclohexadepsipetides enniatin B, B1 and G were isolated from the cultivation broth of Fusarium dimerum Penzig, an endophyte of Magnolia x soulangeana. Their production was about 350 mg l(-1) after 96 h of submerged cultivation in Sabouraud maltose medium. Isolated enniatins inhibited growth of selected microorganisms and activity of 12-lipoxygenase with IC50 = 0.73 mg l(-1).
Firáková
S
S
Department of Biochemical Technology, Institute of Biotechnology and Food Industry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic. silvia.firakova@gmail.com
Sturdíková
M
M
Liptaj
T
T
Prónayová
N
N
Bezákova
L
L
Proksa
B
B
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D047630:Depsipeptides / Q000096:biosynthesis* / Q000302:isolation & purification; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005285:Fermentation; D005670:Fusarium / Q000737:chemistry / Q000378:metabolism*; D000960:Hypolipidemic Agents / Q000302:isolation & purification*; D016859:Lipoxygenase Inhibitors; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013056:Spectrophotometry, Ultraviolet
D047630:Depsipeptides; D004791:Enzyme Inhibitors; D000960:Hypolipidemic Agents; D016859:Lipoxygenase Inhibitors; C100264:enniatins