title: Health-related quality of life of outpatients with systolic and isolated diastolic dysfunction: Sado Heart Failure Study.
abstract: BACKGROUND
  The impact of isolated diastolic dysfunction (IDD) and systolic dysfunction (SD) on health-related quality of life (HRQOL) is unknown.
  
  
  RESULTS
  To evaluate HRQOL in patients with IDD and SD under treatment, information on outpatients aged 60-84 years was extracted from the records of 4,500 consecutive individuals who underwent echocardiographic examination at Sado General Hospital. The medical records of these patients were reviewed and a questionnaire, including the Medical Outcome Study Short Form 36, was mailed to 71 IDD and 99 SD patients; answers were obtained from 66 and 91 patients, respectively. The HRQOL of patients with cardiac dysfunction was impaired even when echocardiographic parameters improved with treatment. Patients with IDD showed an impairment of HRQOL similar to those with SD. Compared with males, female patients had a larger and more significant reduction in the physical and mental components of the HRQOL score. These scores correlated positively with exercise capacity in patients with IDD or SD.
  
  
  CONCLUSIONS
  Impaired HRQOL, in both its mental and physical components, is a serious problem for IDD and SD patients under treatment. Because exercise intolerance may underlie the reduced HRQOL, improving exercise capacity could be an important target for managing outpatients with heart failure.
authors: Division of Cardiology, First Department of Internal Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors: Yukiko
authors: Y
authors: Ohno
authors: Yuji
authors: Y
authors: Okura
authors: Mahmoud M
authors: MM
authors: Ramadan
authors: Koji
authors: K
authors: Taneda
authors: Keisuke
authors: K
authors: Suzuki
authors: Manabu
authors: M
authors: Tomita
authors: Kazuhisa
authors: K
authors: Hao
authors: Shinpei
authors: S
authors: Kimura
authors: Makoto
authors: M
authors: Hoyano
authors: Wataru
authors: W
authors: Mitsuma
authors: Komei
authors: K
authors: Tanaka
authors: Takeshi
authors: T
authors: Kashimura
authors: Masahiro
authors: M
authors: Ito
authors: Satoru
authors: S
authors: Hirono
authors: Haruo
authors: H
authors: Hanawa
authors: Makoto
authors: M
authors: Kodama
authors: Yoshifusa
authors: Y
authors: Aizawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D004452:Echocardiography; D005260:Female; D054144:Heart Failure, Diastolic / Q000503:physiopathology* / Q000628:therapy; D054143:Heart Failure, Systolic / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D011788:Quality of Life