title: An overview of hypofractionation and introduction to this issue of seminars in radiation oncology.
authors: Robert D
authors: RD
authors: Timmerman
mesh_terms: D019583:Dose Fractionation, Radiation; D004307:Dose-Response Relationship, Radiation; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007432:Intraoperative Period; D009369:Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology*; D018787:Radiation Oncology; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects* / Q000266:history; D013997:Time Factors