[Real-time polymerase chain reaction in the diagnosis of pulmonary tuberculosis].
To enhance the efficiency of diagnosis of oligo- and abacillar pulmonary tuberculosis and its differential diagnosis with other lung diseases, the authors studied the informative value of real-time polymerase chain reaction (PCR) used in 62 patients with different clinical forms of tuberculosis and 108 differentially diagnostic patients. Real-time PCR has been ascertained to be a significantly more sensitive and highly specific tool in tuberculosis diagnosis, which considerably improves the specific recognition of the etiology of a pathogenetic process in oligo- and abacillar patients. Particularly encouraging results have been obtained when examining differentially diagnostic patients with the rounded shadows being formed in the lung.
Salina
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TIu
Morozova
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D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery*; D016133:Polymerase Chain Reaction / Q000379:methods*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D014801:Vitamin A / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use
D000995:Antitubercular Agents; D014801:Vitamin A; D014810:Vitamin E