Plasma cell dyscrasia; LCDD vs Immunotactoid glomerulopathy.
Light chain deposit disease is a plasma cell disorder characterized by production of a large amount of monoclonal immunoglobulin light chain or part of it, which is usually deposited as an amorphous substance in the kidneys. Immunotactoid glomerulopathy is an uncommon disease, which might be related to plasma cell dyscrasia, and characteristically manifest as organized glomerular ultra structural fibrils or microtubules. In this article, we report a case of a combined presentation of light chain disease and immunotactoid glomerulopathy in a patient with multiple myeloma and reversible advanced renal failure.
Jabur
Wael L
WL
Nephrology Department, Al-Karamah Teaching Hospital, Baghdad, Iraq, . drwaellatif@hotmail.com
Saeed
Hareth M
HM
Abdulla
Khalid
K
D000740:Anemia / Q000453:epidemiology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D002762:Cholecalciferol / Q000627:therapeutic use; D004921:Erythropoietin / Q000627:therapeutic use; D005919:Glomerular Filtration Rate; D005921:Glomerulonephritis / Q000097:blood / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000097:blood*; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D016896:Treatment Outcome
D000806:Angiotensin-Converting Enzyme Inhibitors; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D011994:Recombinant Proteins; D004921:Erythropoietin; D002762:Cholecalciferol