Disseminated salmonellosis in a patient treated with temozolomide.
Temozolomide is a relatively new chemotherapeutic agent frequently associated with selective CD4+ T-lymphocytopenia. Patients with cell-mediated immune defects are at higher risk for acquiring infections with Salmonella species. We describe the first case of disseminated salmonellosis in a patient treated with temozolomide.
Georgescu
Georgiana
G
University of Texas M.D. Anderson Cancer Center, 1400 Pressler, Unit 1460, Houston, TX 77030, USA. georgiana.georgescu@uth.tmc.edu
Isola
Ignatio M
IM
Youssef
Souad
S
Adachi
Javier
J
Rolston
Kenneth
K
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects* / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000188:drug therapy; D001254:Astrocytoma / Q000188:drug therapy / Q000276:immunology*; D001372:Aza Compounds / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy; D001932:Brain Neoplasms / Q000188:drug therapy / Q000276:immunology*; D003606:Dacarbazine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004322:Drainage; D024841:Fluoroquinolones; D005490:Focal Infection / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D000077266:Moxifloxacin; D011804:Quinolines / Q000627:therapeutic use; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy; D000077204:Temozolomide
D000890:Anti-Infective Agents; D018906:Antineoplastic Agents, Alkylating; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D003606:Dacarbazine; D000077266:Moxifloxacin; D000077204:Temozolomide