title: Low-risk gestational trophoblastic neoplasia: evaluating the need for initial inpatient treatment during low-dose methotrexate chemotherapy.
abstract: OBJECTIVE
  To evaluate the need for initial inpatient treatment for patients being treated with low-dose intramuscular methotrexate for low-risk gestational trophoblastic neoplasia (GTN).
  
  
  METHODS
  Clinical notes of all patients treated with low-dose intramuscular methotrexate for low-risk GTN were analyzed and side effects noted.
  
  
  RESULTS
  There were no episodes of increased uterine bleeding requiring extra medical intervention. There were 7 cases of chest pain; none required a change from methotrexate chemotherapy.
  
  
  CONCLUSIONS
  Patients being treated with low-dose intramuscular methotrexate for low-risk GTN do not need to be treated routinely in the hospital for their first treatment cycle.
authors: Trophoblastic Tumour Centre, Weston Park Hospital, Sheffield, UK.
authors: Lucy D
authors: LD
authors: Carter
authors: Barry W
authors: BW
authors: Hancock
authors: Janet E
authors: JE
authors: Everard
mesh_terms: D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000188:drug therapy*; D006301:Health Services Needs and Demand; D006760:Hospitalization; D006801:Humans; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy; D012189:Retrospective Studies
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate