title: The Application of Vinylogous Iminium Salt Derivatives and Microwave Accelerated Vilsmeier-Haack Reactions to Efficient Relay Syntheses of the Polycitone and Storniamide Natural Products.
abstract: Studies directed at the synthesis of polycitone and storniamide natural products via vinylogous iminium salts and microwave accelerated Vilsmeier-Haack formylations are described. The successful strategy relies on the formation of a 2,4-disubstituted pyrrole or a 2,3,4-trisubstituted pyrrole from a vinamidinium salt or vinamidinium salt derivative followed by formylation at the 5-position of the pyrrole. Subsequent transformations of the selectively formylated pyrroles lead to efficient and regiocontrolled relay syntheses of the respective pyrrole containing natural products.
authors: Department of Chemistry, University of Richmond, Richmond, VA 23173, USA.
authors: John T
authors: JT
authors: Gupton
authors: Edith J
authors: EJ
authors: Banner
authors: Melissa D
authors: MD
authors: Sartin
authors: Matthew B
authors: MB
authors: Coppock
authors: Jonathan E
authors: JE
authors: Hempel
authors: Anastasia
authors: A
authors: Kharlamova
authors: Daniel C
authors: DC
authors: Fisher
authors: Ben C
authors: BC
authors: Giglio
authors: Kristin L
authors: KL
authors: Smith
authors: Matt J
authors: MJ
authors: Keough
authors: Timothy M
authors: TM
authors: Smith
authors: Rene P F
authors: RP
authors: Kanters
authors: Raymond N
authors: RN
authors: Dominey
authors: James A
authors: JA
authors: Sikorski