Combining objective and subjective outcomes in cancer-related fatigue: illustrations from a single case report.
Neurophysiologic measurements were made on a patient with multiple lung cancers and severe cancer-related fatigue (CRF) who responded to 5 mg methylphenidate twice daily, titrated to 10 mg twice daily after 2 weeks. She remained at 10 mg twice daily for 8 months. Improvement in severe CRF (Brief Fatigue Inventory score) was associated with normalization of neurophysiologic tests.
Khoshknabi
Dilara Seyidova
DS
The Harry R. Horvitz Center for Palliative Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Davis
Mellar P
MP
Ranganathan
Vinoth K
VK
Siemionow
Vlodek
V
Walsh
Declan
D
Kirkova
Jordanka
J
Yue
Guang H
GH
D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D005221:Fatigue / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008774:Methylphenidate / Q000627:therapeutic use*; D008875:Middle Aged; D009460:Neurologic Examination / Q000379:methods
D000697:Central Nervous System Stimulants; D008774:Methylphenidate