title: Two new triterpenoid saponins from Gymnema sylvestre.
abstract: Two new oleanane-type triterpenoid saponins, gymnemoside-W1 and W2, together with seven known compounds were isolated from the leaves of Gymnema sylvestre R. Br. By means of spectral and chemical analysis, the structures of the new compounds were elucidated as 16 beta-hydroxyl olean-12-en-3-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl]-28-O-beta-D-glucopyranoside(1) and 16 beta,21 beta,28-trihydroxyl-olean-12-ene-3-O-glucoronopyranoside (2). The EtOH/H(2)O extracts of this plant were shown to be able to inhibit glucose absorption in rats.
authors: Chengdu Institute of Biology, the Chinese Academy of Sciences, Chengdu 610041, China.
authors: Xu-Min
authors: XM
authors: Zhu
authors: Ping
authors: P
authors: Xie
authors: Ying-Tong
authors: YT
authors: Di
authors: Shu-Lin
authors: SL
authors: Peng
authors: Li-Sheng
authors: LS
authors: Ding
authors: Ming-Kui
authors: MK
authors: Wang
mesh_terms: D000818:Animals; D031104:Gymnema sylvestre / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D051381:Rats; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D012503:Saponins; D014315:Triterpenes