Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants.
We evaluated the tolerance to immunization of 64 very low birth weight preterm infants. Thirty-three of the infants experienced a cardiorespiratory event after the first vaccination, and 6 of these 33 (18%) had a recurrence after the second vaccination, including 2 infants previously discharged to home. A cardiorespiratory event associated with the first vaccination was the sole risk factor for recurrence identified.
Flatz-Jequier
Aline
A
Department of Pediatrics, Children's Hospital, University Hospitals of Geneva and Medical Faculty of the University of Geneva, Geneva, Switzerland.
Posfay-Barbe
Klara M
KM
Pfister
Riccardo E
RE
Siegrist
Claire-Anne
CA
D001049:Apnea / Q000139:chemically induced / Q000453:epidemiology*; D001919:Bradycardia / Q000139:chemically induced* / Q000453:epidemiology; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007114:Immunization / Q000379:methods*; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D013557:Switzerland / Q000453:epidemiology
D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines