title: Use of an acellular regenerative tissue matrix in combination with vacuum-assisted closure therapy for treatment of a diabetic foot wound.
abstract: Diabetic foot ulcers can be difficult to treat for a variety of reasons, and may result in amputation. The use of skin grafts can often be a useful method of achieving wound coverage and subsequent healing of diabetic foot ulcers; however, this method of treatment requires creation of a donor site wound that adds to the patient's overall wound burden. Application of an acellular regenerative tissue matrix may eliminate the need for harvesting a skin graft in order to cover a nonhealing wound. The use of vacuum-assisted wound closure has been shown to promote an environment that enhances wound bed contraction and surface epithelialization. The combination of an acellular regenerative tissue matrix with vacuum-assisted wound closure can be used to promote healing in the management of a nonhealing diabetic foot wound.
  
  
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authors: Wright State University, Boonshoft School of Medicine, Dayton, OH 45409, USA.
authors: Kyle L
authors: KL
authors: Randall
authors: Branyan A
authors: BA
authors: Booth
authors: Adrian J
authors: AJ
authors: Miller
authors: Corey B
authors: CB
authors: Russell
authors: Richard T
authors: RT
authors: Laughlin
mesh_terms: D003646:Debridement; D017719:Diabetic Foot / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D016038:Skin Transplantation; D023822:Tissue Engineering; D014184:Transplantation, Homologous; D014945:Wound Healing