title: Gle1 does double duty.
abstract: During nuclear export, Gle1 (the nuclear-pore-associated mRNA export factor) activates the DEAD-box protein Dbp5 to remodel exported mRNA-protein complexes on the cytoplasmic face of the nuclear pore complex. In this issue, Bolger et al. (2008) now report additional roles for Gle1 in translation initiation and termination.
authors: Institute of Biochemistry, ETH Zurich, Schafmattstrasse 18, CH-8093 Zürich, Switzerland. ulrike.kutay@bc.biol.ethz.ch
authors: Ulrike
authors: U
authors: Kutay
authors: Vikram Govind
authors: VG
authors: Panse
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism*; D008954:Models, Biological; D028861:Nuclear Pore Complex Proteins; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; C101408:GLE1 protein, S cerevisiae; D028861:Nuclear Pore Complex Proteins; D012333:RNA, Messenger; D029701:Saccharomyces cerevisiae Proteins