title: Comparison of Pediatric Voice Outcome Survey, Reflux Symptom Index, Reflux Finding Score, and esophageal biopsy results.
abstract: OBJECTIVE
  To examine correlations between the Pediatric Voice Outcome Survey (PVOS) score, the Reflux Symptom Index (RSI) score, the Reflux Finding Score (RFS), and esophageal biopsy findings in children undergoing upper aerodigestive tract endoscopy.
  
  
  METHODS
  Retrospective review of pediatric voice quality-of-life and laryngopharyngeal reflux surveys. Blinded assessment of endoscopic laryngeal images.
  
  
  METHODS
  Tertiary care children's hospital.
  
  
  METHODS
  The study included 36 children with the primary problem of dysphonia (n = 28) or cough (n = 8) who underwent endoscopy.
  
  
  METHODS
  The PVOS and the RSI were administered to the patient's parents before surgery. The patients underwent laryngotracheobronchoscopy and esophageal biopsy. Four raters independently assigned an RFS to the laryngeal photographs.
  
  
  METHODS
  The assessment included (1) PVOS scores, RSI scores, and RFSs; (2) internal consistency of PVOS and RSI scores; (3) RFS intrarater and interrater reliability; and (4) correlations between PVOS score, RSI score, RFS, and esophageal biopsy findings.
  
  
  RESULTS
  The mean (SD) age of the patients was 7.5 (2.6) years; the mean (SD) PVOS score, 71.9 (21.4); and the mean (SD) RSI score, 16.2 (9.1). The PVOS and the RSI scores demonstrated good internal consistency (Cronbach alpha = 0.79 and 0.78, respectively). The RFS exhibited good intrarater reliability (r = 0.66-0.98) and moderate interrater reliability (r = 0.32-0.70). The PVOS and RSI instruments displayed significant correlation (r = -0.30; P = .04). There were no other significant correlations between RFSs, esophageal biopsy results, PVOS scores, or RSI scores (P > .05).
  
  
  CONCLUSIONS
  The RSI may be a useful parent-proxy instrument in addition to the PVOS for pediatric voice patients. The RFS is reliable in children, but its validity could not be demonstrated in this patient population.
authors: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine, 3705 Fifth Ave, Pittsburgh, PA 15213, USA.
authors: Jeffrey P
authors: JP
authors: Simons
authors: Clark A
authors: CA
authors: Rosen
authors: Margaretha L
authors: ML
authors: Casselbrant
authors: David H
authors: DH
authors: Chi
authors: Barry M
authors: BM
authors: Schaitkin
authors: Elaine N
authors: EN
authors: Rubinstein
authors: David L
authors: DL
authors: Mandell
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001999:Bronchoscopy; D002648:Child; D002675:Child, Preschool; D003371:Cough / Q000209:etiology / Q000473:pathology; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology; D006306:Health Surveys; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology; D007828:Laryngoscopy; D008297:Male; D017063:Outcome Assessment, Health Care; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology; D015203:Reproducibility of Results; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D014832:Voice Disorders / Q000209:etiology* / Q000473:pathology; D014833:Voice Quality