Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex.
An efficient and practical catalytic system for the anti-Markovnikov ruthenium-catalyzed hydroarylation of styrenes with acetophenone, allowing a straightforward access to bibenzyl backbones, is described for the first time: this process, involving regioselective C-H bond activation, is complementary to a Friedel-Crafts type reaction giving the branched adduct.
Martinez
Rémi
R
Laboratoire de Synthèse Sélective Organique (UMR 7573, CNRS), Ecole Nationale Supérieure de Chimie de Paris, 11 rue P&M Curie, Paris cedex 05, France.
Genet
Jean-Pierre
JP
Darses
Sylvain
S