A general one-step synthesis of beta-nitronitriles.
The unusual beta-nitronitrile functionality was prepared by a simple one-step hydrocyanation of nitroalkenes. These compounds were shown to be precursors to monoprotected 1,3-diamines and 1,3-amino alcohols through the in situ formation of an alpha-cyano-aldenyde.
Anderson
James C
JC
School of Chemistry, University of Nottingham, Nottingham, NG7 2RD, UK. j.anderson@nottingham.ac.uk
Blake
Alexander J
AJ
Mills
Matthew
M
Ratcliffe
Paul D
PD
D000475:Alkenes / Q000737:chemistry; D003486:Cyanides / Q000737:chemistry; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry
D000475:Alkenes; D003486:Cyanides; D009570:Nitriles