[Macrophagic myofascitis vs atypical Whipple's disease].
A 39-year-old man presented pronounced asthenia and diffuse myalgias 8 months after a vaccination against the tetanus toxoid. Muscle biopsy disclosed infiltration of the perimysium and endomysium by densely packed, PAS-positive macrophages. Tropheryma whippelii detection in blood and faeces allowed the initial assumption of atypical Whipple's disease with isolated muscle involvement. However, the histological detection of aluminium-containing macrophages by means of Morin stain immunofluorescence established the diagnosis of macrophagic myofascitis in an obviously asymptomatic T. whippelii carrier.
Spengos
K
K
Eginition Krankenhaus, Neurologische Universitätsklinik Athen, Vas. Sofias 72, 11528, Athen, Greece. konstantinos.spengos@gmail.com
Vontzalidis
A
A
Vassilopoulou
S
S
Manta
P
P
D000328:Adult; D000535:Aluminum / Q000032:analysis; D001706:Biopsy; D003937:Diagnosis, Differential; D005208:Fasciitis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000175:diagnosis* / Q000473:pathology; D016133:Polymerase Chain Reaction; D013745:Tetanus Toxoid / Q000008:administration & dosage / Q000009:adverse effects; D054851:Tropheryma / Q000235:genetics; D008061:Whipple Disease / Q000175:diagnosis* / Q000473:pathology
D013745:Tetanus Toxoid; D000535:Aluminum