Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery.
Ghose
Arup K
AK
Department of Medicinal Chemistry, Cephalon, Inc., 145 Brandywine Parkway, West Chester, Pennsylvania 19380, USA. aghose@cephalon.com
Herbertz
Torsten
T
Pippin
Douglas A
DA
Salvino
Joseph M
JM
Mallamo
John P
JP
D001665:Binding Sites; D030562:Databases, Protein; D015195:Drug Design; D006801:Humans; D008024:Ligands; D047428:Protein Kinase Inhibitors / Q000737:chemistry* / Q000145:classification; D021281:Quantitative Structure-Activity Relationship
D008024:Ligands; D047428:Protein Kinase Inhibitors