title: Successful prevention of multidrug resistant HIV mother-to-child transmission with enfuvirtide use in late pregnancy.
abstract: The availability of antiretroviral therapy has dramatically reduced the risk of HIV mother-to-child transmission (MTCT). However, mothers infected with multidrug resistant HIV (MDR-HIV) are at increased risk of MTCT. We report the case of a pregnant patient infected with MDR-HIV in whom MTCT was avoided with enfuvirtide use in late pregnancy and elective caesarean section.
authors: Department of Infectious Diseases, University of Sassari, Via De Nicola 1, Sassari, Italy. giordano.madeddu@uniss.it
authors: Giordano
authors: G
authors: Madeddu
authors: Giovanna Maria
authors: GM
authors: Calia
authors: Maria Licinia
authors: ML
authors: Campus
authors: Carla
authors: C
authors: Lovigu
authors: Marco
authors: M
authors: Mannazzu
authors: Paolina
authors: P
authors: Olmeo
authors: Maria Graziella
authors: MG
authors: Mela
authors: Maria Stella
authors: MS
authors: Mura
mesh_terms: D000328:Adult; D018791:CD4 Lymphocyte Count; D002585:Cesarean Section; D024921:Drug Resistance, Multiple, Viral; D000077560:Enfuvirtide; D005260:Female; D015700:HIV Envelope Protein gp41 / Q000627:therapeutic use*; D023581:HIV Fusion Inhibitors / Q000627:therapeutic use*; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D010446:Peptide Fragments / Q000627:therapeutic use*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D015700:HIV Envelope Protein gp41; D023581:HIV Fusion Inhibitors; D010446:Peptide Fragments; D000077560:Enfuvirtide