title: Traumatic neuromas of the penis: a clinical, histopathological and immunohistochemical study of 17 cases.
abstract: We present 17 penile traumatic neuromas. The mean patient age at presentation was 38 years (range 23-59 years). The most common site involved was the penile shaft. The lesions ranged from 1 to 7 mm in greatest dimension. The clinical diagnosis in all cases included condyloma acuminatum. In all cases, a history of trauma because of prior biopsy and/or circumcision was found. Histologically, all lesions showed similar features consisting of an increased number of dermal nerve bundles embedded within a fibrous stroma. Often, single or multiple Meissner corpuscle-like structures were noted in the papillary dermis. Our study suggests that circumcision or other forms of trauma to the skin of the penis likely plays an important role in the pathogenesis and clinical presentation of this peculiar neural neoplasm. We call attention to this entity because it is often clinically misdiagnosed as condyloma acuminatum.
authors: Department of Dermatology, Odessa Medical Center, Odessa, TX, USA.
authors: Eduardo
authors: E
authors: Salcedo
authors: Anthony C
authors: AC
authors: Soldano
authors: Lesley
authors: L
authors: Chen
authors: Cameron K
authors: CK
authors: Rokhsar
authors: Sam T
authors: ST
authors: Tam
authors: Shane A
authors: SA
authors: Meehan
authors: Hideko
authors: H
authors: Kamino
mesh_terms: D000328:Adult; D002944:Circumcision, Male / Q000009:adverse effects; D003218:Condylomata Acuminata / Q000473:pathology; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D008875:Middle Aged; D009463:Neuroma / Q000209:etiology / Q000473:pathology*; D010412:Penile Neoplasms / Q000209:etiology / Q000473:pathology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology*; D014947:Wounds and Injuries / Q000150:complications / Q000473:pathology*