Graft versus host disease-related Hafnia alvei colonization and probable infection.
We describe the case of a graft versus host disease (GvHD) patient, in whom Hafnia alvei was cultured as a single organism, and at high bacterial counts from stool samples, from the onset of the disease until its resolution. This case is a further example of the contentious role of this species in causing human intestinal disease. Furthermore, it focuses on enteric damage by GvHD as a risk factor for acquiring H. alvei colonization, and probably infection.
Savini
Vincenzo
V
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Di Bartolomeo
Erminia
E
Department of Hematology, Bone Marrow Transplant Centre, Spirito Santo Hospital, Pescara, Italy.
Catavitello
Chiara
C
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Talia
Marzia
M
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Manna
Assunta
A
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Febbo
Fabio
F
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Balbinot
Andrea
A
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
Di Bonaventura
Giovanni
G
Department of Biomedical Sciences, Gabriele d'Annunzio University, Chieti-Pescara, Italy.|Clinical Microbiology, Aging Research Center (Ce.S.I.), Gabriele d'Annunzio University, Chieti-Pescara, Italy.
Di Bartolomeo
Paolo
P
Department of Hematology, Bone Marrow Transplant Centre, Spirito Santo Hospital, Pescara, Italy.
Piccolomini
Raffaele
R
Department of Biomedical Sciences, Gabriele d'Annunzio University, Chieti-Pescara, Italy.|Clinical Microbiology, Aging Research Center (Ce.S.I.), Gabriele d'Annunzio University, Chieti-Pescara, Italy.
D'Antonio
Domenico
D
Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002353:Carrier State / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D004756:Enterobacteriaceae Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D005199:Fanconi Anemia / Q000150:complications / Q000628:therapy; D005243:Feces / Q000382:microbiology; D005260:Female; D005759:Gastroenteritis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D006086:Graft vs Host Disease / Q000150:complications*; D020611:Hafnia alvei / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D033581:Stem Cell Transplantation
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents