[Precocious pubertal].
Precocious pubertal is frequent and should lead to a rigorous evaluation. It is important to precisely evaluate the timing of pubertal development, and to search for an hypothalamic lesion in cases of central precocious puberty. It is also important to recognize that many cases of precocious puberty will not progress and therefore do not need treatment. When central precocious puberty has been confirmed, GnRH agonists should be considered. Management issues, as well as long term results of these treatments are presented.
Carel
Jean-Claude
JC
Service d'endocrinologie-diabétologie pédiatrique, centre de référence des maladies endocriniennes rares de la croissance, hôpital Robert-Debré, Université Paris-Diderot Paris-7, 75935 Paris Cedex 19, France. jean-claude.carel@inserm.fr
Zenaty
Delphine
D
Paulsen
Anne
A
Simon
Dominique
D
Léger
Juliane
J
D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D006801:Humans; D011629:Puberty, Precocious / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology* / Q000523:psychology
D007987:Gonadotropin-Releasing Hormone