Outcome and management of pregnancy in women with thalassaemia in Cyprus.
We describe the management and clinical outcome of pregnancies among 100 Greek Cypriot women with thalassaemia: 88 with thalassaemia major and 12 with thalassaemia intermedia. A total of 152 successful pregnancies and 161 deliveries were included. All patients had endocrine assessment and frequent ferritin measurements. Multiple successful pregnancies included 7 twins and 1 triple pregnancy. Pregnant thalassaemics required significantly larger amount of total blood transfusion during pregnancy. There was a statistically significant increase in the ferritin levels during pregnancy, and levels remained significantly higher after pregnancy. Most pregnancies resulted in delivery of full-term healthy babies, and obstetric complications were rare, although some problems were encountered.
Toumba
M
M
Paediatric Endocrine Unit, Department of Paediatrics, Makarios Hospital, Nicosia, Cyprus.
Kanaris
C
C
Simamonian
K
K
Skordis
N
N
D000359:Aftercare; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D036861:Delivery, Obstetric / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D005293:Ferritins / Q000097:blood; D005817:Genetic Counseling; D006115:Greece / Q000453:epidemiology; D006301:Health Services Needs and Demand; D006801:Humans; D008991:Monitoring, Physiologic; D011181:Postnatal Care / Q000458:organization & administration*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011295:Prenatal Care / Q000458:organization & administration*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D013789:Thalassemia / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*
D005293:Ferritins