title: Measurement of problem behaviour during medication evaluations.
abstract: BACKGROUND
  The focus of this review is on methods that are currently being used to evaluate the behavioural effects of medication for individuals with intellectual disabilities. First we describe what has been identified as the ideal criteria for conducting clinical trials and how these criteria may be adapted to do less controlled evaluations. The central theme is a review of the biological measures (e.g. labs, drug levels), behavioural rating scales and direct observation measures that are often used to evaluate medication effects. Issues related to how the side effects of medication can affect behaviour will also be discussed.
  
  
  CONCLUSIONS
  The importance of encouraging communication and collaboration across all systems of care and the use of socially valid measures are discussed.
authors: University of Rochester Medical Center, Rochester, New York 14642, USA. Jennifer_Zarcone@URMC.Rochester.edu
authors: J
authors: J
authors: Zarcone
authors: D
authors: D
authors: Napolitano
authors: M
authors: M
authors: Valdovinos
mesh_terms: D001521:Behavior Therapy; D003131:Combined Modality Therapy; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000523:psychology; D001523:Mental Disorders / Q000188:drug therapy* / Q000523:psychology; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D012017:Referral and Consultation; D016896:Treatment Outcome
chemical_list: D011619:Psychotropic Drugs