title: The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture.
abstract: Drug-eluting stents (DES) have made a tremendous impact on the practice of percutaneous coronary intervention. Recently however, long-term DES failures have become a focal point, particularly with restenosis and thrombosis. An uncommon, yet important cause of DES failure is stent fracture. Of the two established first generation DES, the sirolimus-eluting stent (SES) has been particularly linked to cases of stent fracture, likely as a result of its closed cell design compared with other DES employing an open cell system. We present 2 cases of SES fracture confirmed using high-resolution intravascular optical coherence tomography giving unique insights into the in-vivo appearance of this complication.
authors: Peter
authors: P
authors: Barlis
authors: Georgios
authors: G
authors: Sianos
authors: Giuseppe
authors: G
authors: Ferrante
authors: Francesca
authors: F
authors: Del Furia
authors: Savio
authors: S
authors: D'Souza
authors: Carlo
authors: C
authors: Di Mario
mesh_terms: D000368:Aged; D023903:Coronary Restenosis / Q000000981:diagnostic imaging* / Q000209:etiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D020123:Sirolimus / Q000008:administration & dosage*; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000706:statistics & numerical data; D014463:Ultrasonography
chemical_list: D020123:Sirolimus