title: Management of acute bronchiolitis: can evidence based guidelines alter clinical practice?
abstract: BACKGROUND
  Acute bronchiolitis is the most common lower respiratory tract infection in infants and there is no evidence that drug treatment alters its natural course. Despite this, most Swiss paediatricians reported in 2001 prescribing bronchodilators and inhaled corticosteroids (ICS). This situation led to the creation of national guidelines followed by a tailored implementation programme. The aim of this study was to examine if treatment practices changed after the implementation of the new guidelines.
  
  
  METHODS
  A questionnaire on treatment of bronchiolitis was sent to all Swiss paediatricians before (2001) and after (2006) creation and implementation of national guidelines (2003-2005). Guidelines were created in collaboration with all paediatric pulmonologists and implemented carefully using a multifaceted approach.
  
  
  RESULTS
  Questionnaires were returned by 541 paediatricians (58%) in 2001 and by 639 (54%) in 2006. While both surveys showed a wide variation in the treatment of bronchiolitis between physicians, reported drug prescription decreased significantly between the two surveys. For outpatients, general use (for all patients) of bronchodilators dropped from 60% to 23%, and general use of ICS from 34% to 6%. For inpatients, general use of bronchodilators and ICS dropped from 55% to 18% and from 26% to 6%, respectively (all p<0.001). The decrease was evident in all regions, among hospital and primary care physicians, and among general paediatricians and paediatric pulmonologists.
  
  
  CONCLUSIONS
  National guidelines together with a tailored implementation programme can have a major impact on medical management practices in a country.
authors: Paediatric Pulmonology, Children's Hospital, CH-9006 St Gallen, Switzerland. juerg.barben@kispisg.ch
authors: J
authors: J
authors: Barben
authors: C E
authors: CE
authors: Kuehni
authors: D
authors: D
authors: Trachsel
authors: J
authors: J
authors: Hammer
mesh_terms: D000208:Acute Disease; D000420:Albuterol / Q000627:therapeutic use; D000553:Ambulatory Care; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001988:Bronchiolitis / Q000188:drug therapy*; D002648:Child; D003430:Cross-Sectional Studies; D019317:Evidence-Based Medicine; D006760:Hospitalization; D006801:Humans; D010372:Pediatrics; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011364:Professional Practice; D013256:Steroids / Q000627:therapeutic use; D013557:Switzerland
chemical_list: D000900:Anti-Bacterial Agents; D013256:Steroids; D000420:Albuterol