title: AMIN domains have a predicted role in localization of diverse periplasmic protein complexes.
abstract: We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we suggest that AMIN domains mediate the targeting of periplasmic or extracellular proteins to specific regions of the bacterial envelope.
authors: Departamento de Bioquímica, Universidade de São Paulo, São Paulo, Brazil.
authors: Robson Francisco
authors: RF
authors: de Souza
authors: Vivek
authors: V
authors: Anantharaman
authors: Sandro José
authors: SJ
authors: de Souza
authors: L
authors: L
authors: Aravind
authors: Frederico J
authors: FJ
authors: Gueiros-Filho
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000032:analysis / Q000737:chemistry*; D008957:Models, Genetic; D008969:Molecular Sequence Data; D033903:Periplasmic Proteins / Q000032:analysis / Q000737:chemistry*; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment
chemical_list: D001426:Bacterial Proteins; D033903:Periplasmic Proteins