title: [Effect of tear film changes on the intraocular pressure measurement by Goldmann applanation tonometer].
abstract: OBJECTIVE
  To explore the effect of tear film changes on the intraocular pressure (IOP) measurement by Goldmann applanation tonometer.
  
  
  METHODS
  Sixty-eight normal subjects were randomly divided into two groups (Group A and B), 34 in each group. One eye of each subject by random selection was given Dextran (in Group A) and Viscoat (in Group B), respectively. And the fellow eyes were used as controls. IOP was measured in all subjects twice using Goldmann applanation tonometer. And the difference between first and second measurements was compared.
  
  
  RESULTS
  In the control eyes of Group A, the average IOP of first and second measurements were (14.44 +/- 2.68) mmHg (1 mmHg = 0.133 KPa) and (14.47 +/- 2.69) mmHg, there was no difference between the two measurements (t = -0.329, P = 0.744). In eyes given Dextran, the average IOP of two measurements were (14.41 +/- 2.63) mmHg and (12.94 +/- 2.59) mmHg, there was significant difference between the two measurements (t = 13.949, P = 0.000). In control eyes of Group B, the average IOP of first and second measurements were (14.53 +/- 3.13) mmHg and (11.18 +/- 3.07) mmHg, and there was no difference between the two measurements (t = -0.466, P = 0.644). In eyes given Viscoat, the average IOP of two measurements were (14.53 +/- 3.13) mmHg and (11.18 +/- 3.07) mmHg, and there was significant difference between the two measurements (t = 22.126, P = 0.000). After being given Dextran or Viscoat, the IOP values decreased consistently in both Group A and Group B.
  
  
  CONCLUSIONS
  The change of tear film components can affect IOP values by Goldmann applanation tonometer.
authors: State Key Laboratory of Ophthlamology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
authors: Yangfa
authors: Y
authors: Zeng
authors: Xinxing
authors: X
authors: Guo
authors: Jun
authors: J
authors: Lin
authors: Xiangyun
authors: X
authors: Zeng
authors: Yiming
authors: Y
authors: Zhong
authors: Xiaoyu
authors: X
authors: Cai
authors: Xing
authors: X
authors: Liu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D013666:Tears; D014065:Tonometry, Ocular / Q000379:methods*