Primary bilateral multifocal choroiditis as an initial manifestation of disseminated cryptococcosis in a HIV-positive patient.
OBJECTIVE
To report a rare case of primary bilateral multifocal choroiditis due to disseminated cryptococcus infection in a HIV-positive patient.


METHODS
Retrospective report. A 30-year-old asymptomatic HIV-positive male referred to us for a routine ophthalmic evaluation had bilateral, multiple choroidal lesions. CSF confirmed cryptococcus by India ink preparation and antigen by latex agglutination. The lesions began to resolve with intravenous amphotericin B and oral fluconazole.


CONCLUSIONS
Asymptomatic, primary, bilateral multifocal choroiditis due to cryptococcus is rare. A routine ophthalmic examination in HIV-positive patients can alert the treating physician to a possibility of a fatal disease.
Babu
Kalpana
K
Prabha Eye Clinic and Research Centre and Vittala International Institute of Ophthalmology, Bangalore, India. kb 7375@yahoo.co.in
Murthy
Krishna R
KR
Rajagopalan
Nirmala
N
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002833:Choroiditis / Q000382:microbiology*; D003453:Cryptococcosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D017809:Fatal Outcome; D015725:Fluconazole / Q000627:therapeutic use; D005451:Fluorescein Angiography; D007839:Functional Laterality; D006679:HIV Seropositivity / Q000150:complications; D006801:Humans; D008297:Male; D012189:Retrospective Studies
D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole