Keeping plants in shape: polycomb-group genes and histone methylation.
The Polycomb-group proteins (Pc-G) are transcriptional repressors that control many key developmental transitions in plants. Recent whole genome profiling of the histone methylation marks that are characteristic of the Pc-G have suggested many novel targets of Pc-G regulation. However, the number and nature of targets also suggests that Pc-G regulation may be much more dynamic than hitherto assumed. We discuss the role of histone methylation in gene regulation, the complexes involved in setting and reading the mark and how activity states may be reset during development.
Schatlowski
Nicole
N
Institute of Genetics, Heinrich-Heine-University Duesseldorf, Universitaetsstr. 1, Germany.
Creasey
Kate
K
Goodrich
Justin
J
Schubert
Daniel
D
D000818:Animals; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D006657:Histones / Q000378:metabolism*; D046911:Macromolecular Substances; D008745:Methylation; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D010944:Plants / Q000235:genetics*; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins / Q000235:genetics*
D006657:Histones; D046911:Macromolecular Substances; D010940:Plant Proteins; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins