title: Subsequent pregnancy outcomes in patients with molar pregnancy and persistent gestational trophoblastic neoplasia.
abstract: OBJECTIVE
  To evaluate the subsequent reproductive outcomes in patients with complete and partial molar pregnancy and gestational trophoblastic neoplasia (GTN) at the New England trophoblastic Disease Center between June 1, 1965, and December 31, 2007.
  
  
  METHODS
  Questionnaires regarding subsequent pregnancies were mailed to all patients with current mailing addresses at the New England Trophoblastic Disease Center.
  
  
  RESULTS
  The subsequent reproductive outcomes in patients with complete and partial molar pregnancies and persistent GTN were in general the same as those in the general population. However, after an episode of molar pregnancy the incidence of molar pregnancy in a later gestation was approximately 1%. Additionally, after successful chemotherapy for GTN, the incidence of stillbirth was 1.4% in later pregnancies.
  
  
  CONCLUSIONS
  Patients with molar pregnancies and GTN should be reassured that they can in general expect a normal future reproductive outcome.
authors: New England Trophoblastic Disease Center, Boston, MA, USA.
authors: Leslie A
authors: LA
authors: Garrett
authors: Elizabeth I O
authors: EI
authors: Garner
authors: Colleen M
authors: CM
authors: Feltmate
authors: Donald P
authors: DP
authors: Goldstein
authors: Ross S
authors: RS
authors: Berkowitz
mesh_terms: D005260:Female; D031901:Gestational Trophoblastic Disease / Q000453:epidemiology*; D006801:Humans; D006828:Hydatidiform Mole / Q000453:epidemiology; D008404:Massachusetts / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D012042:Registries