[Apoptosis and pathological process].
Apoptosis (programmed cell death) occurs normally for maitenance of tissue homeostasis and play an important role in morphogenesis, embriogenesis and tissue growth. On the other hand, apoptosis may be involved in different pathological processes such as malignancy, infectious diseases and autoimmune disorders. Apoptosis is regulated by various mediators. Caspases, death receptors, mitochondria, Bcl-2 protoncogenes and tumor supressor genes are considered to be the most important of them. Advance in apoptosis regulation research suggests enormouse facilities for therapy of wide range of human illnesses.
Rami
Mukhammed Salim Iusef
MS
D000818:Animals; D017209:Apoptosis; D001327:Autoimmune Diseases / Q000473:pathology; D006801:Humans; D009369:Neoplasms / Q000473:pathology; D010336:Pathology