title: Water-stable organic transistors and their application in chemical and biological sensors.
abstract: The development of low-cost, reliable sensors will rely on devices capable of converting an analyte binding event to an easily read electrical signal. Organic thin-film transistors (OTFTs) are ideal for inexpensive, single-use chemical or biological sensors because of their compatibility with flexible, large-area substrates, simple processing, and highly tunable active layer materials. We have fabricated low-operating voltage OTFTs with a cross-linked polymer gate dielectric, which display stable operation under aqueous conditions over >10(4) electrical cycles using the p-channel semiconductor 5,5'-bis-(7-dodecyl-9H-fluoren-2-yl)-2,2'-bithiophene (DDFTTF). OTFT sensors were demonstrated in aqueous solutions with concentrations as low as parts per billion for trinitrobenzene, methylphosphonic acid, cysteine, and glucose. This work demonstrates of reliable OTFT operation in aqueous media, hence opening new possibilities of chemical and biological sensing with OTFTs.
authors: Department of Chemical Engineering, Stanford University, Stauffer III, 381 North-South Mall, Stanford, CA 94305, USA.
authors: Mark E
authors: ME
authors: Roberts
authors: Stefan C B
authors: SC
authors: Mannsfeld
authors: Núria
authors: N
authors: Queraltó
authors: Colin
authors: C
authors: Reese
authors: Jason
authors: J
authors: Locklin
authors: Wolfgang
authors: W
authors: Knoll
authors: Zhenan
authors: Z
authors: Bao
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003545:Cysteine / Q000032:analysis; D005947:Glucose / Q000032:analysis; D009930:Organic Chemicals / Q000032:analysis; D009943:Organophosphorus Compounds / Q000032:analysis; D014173:Transistors, Electronic / Q000592:standards*; D014301:Trinitrobenzenes / Q000032:analysis; D014867:Water
chemical_list: D009930:Organic Chemicals; D009943:Organophosphorus Compounds; D014301:Trinitrobenzenes; D014867:Water; C032627:methylphosphonic acid; D005947:Glucose; D003545:Cysteine