Epigenetic control of myelin repair.
Although the CNS has a robust innate ability to repair demyelinated axons, this capacity appears to dissipate with age. A study in this issue suggests that epigenetic processes participate in myelin repair and that the epigenetic response is less dynamic in older individuals.
Popko
Brian
B
Jack Miller Center for Peripheral Neuropathy, Department of Neurology, University of Chicago, 5841 South Maryland Ave., MC2030, Chicago, Illinois 60637-1470, USA. bpopko@uchicago.edu
D000818:Animals; D044127:Epigenesis, Genetic / Q000502:physiology*; D009186:Myelin Sheath / Q000235:genetics* / Q000378:metabolism*; D009416:Nerve Regeneration / Q000235:genetics*