Rhabdomyosarcoma an ubiquitous pediatric tumour.
Rhabdomyosarcoma is the most common soft tissue tumor in children. It occurs everywhere and its prognosis depends on the location and its histological type--embryonic or alveolar. The new immunohistochemical markers desmin and myogenin in combination with molecular biological detection of specific translocations in alveolar rhabdomyosarcoma improved diagnostic capacities. Less aggressive treatment in curable cases reduces the undesirable outcomes of therapy.
Verkarre
V
V
Anatomical Pathology Department, Surgical Department, Hopital Necker Enfants-Malades 149 rue de sevres 7501 Paris, France.
Galmiche-Rolland
L
L
Sarnacki
S
S
Jaubert
F
F
D002454:Cell Differentiation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D018482:Muscle, Skeletal; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000628:therapy