Folate and vitamin B12 metabolism: overview and interaction with riboflavin, vitamin B6, and polymorphisms.
This paper provides a general review on folate and vitamin B12 nutrition and metabolism and the metabolic interrelationship between these vitamins. The effects of some common polymorphisms in folate and vitamin B12 genes and the influence of vitamin B6 and riboflavin status on folate and vitamin B12 metabolism are also discussed.
Shane
Barry
B
Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA. bandie@berkeley.edu
D001682:Biological Availability; D005492:Folic Acid / Q000235:genetics / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D007408:Intestinal Absorption; D011110:Polymorphism, Genetic; D012256:Riboflavin / Q000378:metabolism / Q000502:physiology*; D014805:Vitamin B 12 / Q000235:genetics / Q000378:metabolism* / Q000493:pharmacokinetics; D025101:Vitamin B 6 / Q000378:metabolism / Q000502:physiology*
D025101:Vitamin B 6; D005492:Folic Acid; D014805:Vitamin B 12; D012256:Riboflavin