Cutaneous polyarteritis nodosa in a patient with Crohn's disease.
A 19-year-old Japanese woman with a 4-year history of Crohn's disease (CD) developed high fever, polyarthralgia, and painful subcutaneous nodules of the legs. A skin biopsy showed panarteritis with fibrinoid necrosis in the deep dermis. Endoscopic examination showed aphthous lesions in the entire colon. She was diagnosed with cutaneous polyarteritis nodosa (PAN) associated with CD. Steroid therapy improved her symptoms. To our knowledge, this is the first Japanese case of cutaneous PAN associated with CD.
Komatsuda
Atsushi
A
Third Department of Internal Medicine, Akita University School of Medicine, and Department of Hematology, Municipal Akita General Hospital, 1-1-1 Hondo, Akita, 010-8543, Japan. komatsud@med.akita-u.ac.jp
Kinoshita
Koji
K
Togashi
Masaru
M
Maki
Nobuki
N
Masai
Rie
R
Niitsu
Hidetaka
H
Ohtani
Setsuya
S
Sageshima
Masato
M
Sawada
Ken-ichi
K
Wakui
Hideki
H
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D019804:Mesalamine / Q000627:therapeutic use; D009336:Necrosis / Q000150:complications / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000098:blood supply / Q000473:pathology*; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D019804:Mesalamine; D011239:Prednisolone