[Determination of triazolam in human urine by gas chromatograph-micro electron capture detector].
Triazolam is often abused in criminal activities. It is necessary to develop a simple, fast and sensitive method for determining triazolam in human urine. After the triazolam in urine was extracted with ether at pH 9, the analysis was performed on an HP-5 capillary column with gas chromatograph-micro electron capture detector (GC-muECD). The calibration curve of triazolam showed good linearity in the range of 0.2 - 50 ng/mL with the correlation coefficient of 0.999 5. The inter-day relative standard deviation (RSD) and intra-day RSD were 4.17% and 5.31%, respectively. The average recovery was 93.9%. This simple, sensitive and accurate method can be easily implemented for monitoring triazolam in urine.
Qin
Huajing
H
Liuzhou Center for Disease Control and Prevention, Liuzhou 545001, China. huajing625@sina.com
D002849:Chromatography, Gas / Q000379:methods*; D004583:Electrons; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D016014:Linear Models; D012997:Solvents / Q000737:chemistry; D013997:Time Factors; D014229:Triazolam / Q000652:urine*; D016482:Urinalysis / Q000379:methods*
D012997:Solvents; D014229:Triazolam