title: Experimental immunosuppression and infection of chickens with Quaranfil virus.
abstract: In ovo hormonal bursectomy of chick embryos was carried out by chorioallantoic membrane inoculation with testosterone propionate at the 18th day of embryonation. At hatching immunosuppression was complemented with sublethal X-irradiation. At 40 days of age the immunomanipulated and control chickens were inoculated subcutaneously with a single dose of Quaranfil virus. It was observed that bursectomy and bursectomy with sublethal X-irradiation prolonged viraemia up to the 20th day following virus infection with a significant reduction of natural haemagglutinins and of virus induced specific antibody response.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
authors.forename: L H
authors.initials: LH
authors.lastname: Saleh
authors.forename: K S
authors.initials: KS
authors.lastname: Abdel-Wahab