TRAP-like protein of Plasmodium sporozoites: linking gliding motility to host-cell traversal.
To reach its final destination in the liver, the sporozoite (the stage of the malaria parasite that is transmitted by the mosquito vector) needs to glide through tissues and traverse host cells. Although the molecular bases of these behaviors are typically considered separately, two recent reports suggest the first molecular link between the two via a novel protein called 'TRAP-like protein'.
Lacroix
Céline
C
Institut Pasteur, Unité de Biologie et Génétique du Paludisme, 28 rue du Dr Roux, 75724 Paris Cedex 15, France.
Ménard
Robert
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