Metachromatic leukodystrophy: magnetic resonance imaging (diffusion weighted image--DWI).
Ten years old patient with juvenile form of metachromatic leukodystrophy (MDL) is presented. Apart from standard magnetic resonance (MR) protocol, the diffusion weighted sequence was performed and apparent diffusion coefficient (ADC) map was constructed. The cause of restricted diffusion is considered to be the deposits of metachromatic substance in the intercellular space, apparently similar reason for decrease of speed of diffusion in other storage diseases.
Seidl
Zdenek
Z
MRI Unit, Department of Radiology, 1st Medical Faculty, Charles University, Prague, Czech Republic. zseid@lf1.cuni.cz
Vaneckova
Manuela
M
Vitak
Tomas
T