Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma: a case report.
A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensity-modulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.
Cho
Jaeho
J
Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University Health System, Seodaemoon-gu, Seoul, Korea. jjhmd@yuhs.ac
Kim
Gwi Eon
GE
Rha
Koon Ho
KH
Ahn
Joong Bae
JB
Lee
Chang Geol
CG
Suh
Chang-Ok
CO
Seong
Jinsil
J
Keum
Ki Chang
KC
Kim
Song Ie
SIe
Lee
Yoon-Hee
YH