title: Ultra-highly sensitive and wash-free bio-detection of H5N1 virus by immunomagnetic reduction assays.
abstract: A platform for assaying avian influenza H5N1 viruses that involves measuring the ac immunomagnetic reduction of a magnetic reagent mixed with a detected sample is developed. The magnetic reagent contained magnetic nanoparticles coated with antibodies. To achieve an ultra-high sensitivity assay, a system utilizing a high-transition-temperature superconducting quantum interference device was used to sense the immunomagnetic reduction of the reagents. The results confirmed the ultra-high sensitivity of the immunomagnetic reduction assay on H5N1.
authors.affiliation: Institute of Electro-optical Science and Technology, National Taiwan Normal University, Taipei 116, Taiwan.
authors.forename: S Y
authors.initials: SY
authors.lastname: Yang
authors.forename: J J
authors.initials: JJ
authors.lastname: Chieh
authors.forename: W C
authors.initials: WC
authors.lastname: Wang
authors.forename: C Y
authors.initials: CY
authors.lastname: Yu
authors.forename: C B
authors.initials: CB
authors.lastname: Lan
authors.forename: J H
authors.initials: JH
authors.lastname: Chen
authors.forename: H E
authors.initials: HE
authors.lastname: Horng
authors.forename: Chin-Yih
authors.initials: CY
authors.lastname: Hong
authors.forename: H C
authors.initials: HC
authors.lastname: Yang
authors.forename: Wilber
authors.initials: W
authors.lastname: Huang