Direct, facile synthesis of N-acyl-alpha-amino amides from alpha-keto esters and ammonia.
N-acyl-alpha-amino amides were prepared, without the necessity of chromatographic purification, in a single step by heating the corresponding alpha-keto ester in methanolic ammonia.
Ntaganda
Rukundo
R
Department of Chemistry & Biochemistry, University of Windsor, 401 Sunset Avenue, Windsor, Ontario, Canada N9B 3P4.
Milovic
Tamara
T
Tiburcio
Jorge
J
Thadani
Avinash N
AN