Intrauterine insemination: is the timing correct?
OBJECTIVE
To evaluate the impact of follicle rupture on pregnancy rate in intrauterine insemination.


METHODS
Retrospective cohort study. Evidence of follicle rupture was assessed by transvaginal ultrasonography following IUI. Two hundred ninety-six couples with unexplained infertility and 121 couples with male factor subfertility were included. Results of 578 cycles were analyzed here.


RESULTS
Clinical pregnancy rate was 23.5% (64/272) in the group when follicle rupture was evident by transvaginal ultrasonography, while it was only 8.8% (27/306) when follicle rupture was not evident (p < 0.001).


CONCLUSIONS
Postponing IUI until observation of follicle rupture may yield a higher pregnancy rate.
Kucuk
Tansu
T
Department of Obstetrics & Gynecology, GATA School of Medicine, Ankara, Turkey. tansukucuk@gmail.com