title: Clinical and serotonergic predictors of non-affective acute remitting psychosis in patients with a first-episode psychosis.
abstract: OBJECTIVE
  The study aimed to establish clinical predictors of non-affective acute remitting psychosis (NARP) and assess whether these patients showed a distinct serotonergic profile.
  
  
  METHODS
  First-episode never treated psychotic patients diagnosed of paranoid schizophrenia (n=35; 21 men and 14 women) or NARP (n=28; 15 men and 13 women) were included.
  
  
  RESULTS
  NARP patients showed significantly lower negative symptomatology, better premorbid adjustment, shorter duration of untreated psychosis, more depressive symptomatology and a lower number of 5-HT2A receptors than the paranoid schizophrenia patients. In the logistic regression, the four variables associated with the presence of NARP were: low number of 5-HT2A receptors; good premorbid adjustment; low score in the item 'hallucinatory behaviour' and reduced duration of untreated psychosis.
  
  
  CONCLUSIONS
  Our findings support the view that NARP is a highly distinctive condition different from either affective psychosis or other non-affective psychosis such as schizophrenia, and highlight the need for its validation.
authors.affiliation: Sant Joan de Deu, Serveis de Salut Mental, Sant Boi de Llobregat, Barcelona, Spain. 24439bam@comb.es
authors.forename: B
authors.initials: B
authors.lastname: Arranz
authors.forename: L
authors.initials: L
authors.lastname: San
authors.forename: N
authors.initials: N
authors.lastname: Ramírez
authors.forename: R M
authors.initials: RM
authors.lastname: Dueñas
authors.forename: V
authors.initials: V
authors.lastname: Perez
authors.forename: J
authors.initials: J
authors.lastname: Salavert
authors.forename: I
authors.initials: I
authors.lastname: Corripio
authors.forename: E
authors.initials: E
authors.lastname: Alvarez