title: HIV-DNA in rectal cells is well correlated with   HIV-DNA in blood in different groups of patients,   including long-term non-progressors.
abstract: Most of the body's lymphoid tissue is in gut and constitutes an immense HIV reservoir. We quantified HIV-DNA in rectum and compared it with blood levels for 27 HIV-infected adults from different groups. We observed a large range of rectal and blood HIV-DNA levels. They were positively correlated (r = 0.841, P<0.0001). Long-term nonprogressors and patients in 'remission' after antiretroviral treatment interruption had the lowest blood and mucosal HIV-DNA levels.
authors.affiliation: AP-HP, Laboratoire de Virologie, CHU Necker -Enfants Malades, Université Paris Descartes, Paris, France. veronique.avettand@nck.aphp.fr
authors.forename: Véronique
authors.initials: V
authors.lastname: Avettand-Fenoel
authors.forename: Thierry
authors.initials: T
authors.lastname: Prazuck
authors.forename: Laurent
authors.initials: L
authors.lastname: Hocqueloux
authors.forename: Adeline
authors.initials: A
authors.lastname: Melard
authors.forename: Christophe
authors.initials: C
authors.lastname: Michau
authors.forename: Rémy
authors.initials: R
authors.lastname: Kerdraon
authors.forename: Eric
authors.initials: E
authors.lastname: Agoute
authors.forename: Christine
authors.initials: C
authors.lastname: Rouzioux