title: The impact of antimicrobial-resistant, health care-associated infections on mortality in the United States.
abstract: We used data reported from US hospitals to the National Nosocomial Infection Surveillance System of the Centers for Disease Control and Prevention for 3 specific infections: Staphylococcus aureus bloodstream infections, Pseudomonas aeruginosa pneumonias, and Escherichia coli urinary tract infections. We evaluated the proportion of infections with antimicrobial-resistant isolates and the relative risk of death associated with the resistant pathogen in the period 2000-2004, compared with the period 1990-1994. The proportion of antimicrobial-resistant infections increased, but there was no change in the relative risk of death between the 2 periods.
authors.affiliation: Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. rmk2@cdc.gov
authors.forename: R Monina
authors.initials: RM
authors.lastname: Klevens
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Edwards
authors.forename: R P
authors.initials: RP
authors.lastname: Gaynes