The prevalence of cognitive impairment with no dementia in older people: the Seoul study.
OBJECTIVE
This study aimed to estimate prevalence of cognitive impairment with no dementia (CIND) in older people. It was conducted in an urban area of Korea, Seoul, and employed a two-stage design for case identification.


METHODS
Overall 643 persons aged 65 years and older participated and 217 persons sampled from the three levels of performance of MMSE underwent a second stage clinical evaluation. CIND was diagnosed when the global Clinical Dementia Rating (CDR) index was 0.5 and the Diagnostic and Statistical Manual of Mental Disorders, 4th edition diagnostic features of dementia were not satisfied. CIND cases without any apparent causes were classified as CIND of unidentified cause (CIND(uc)).


RESULTS
CIND prevalence ranged from 26.3% in persons aged 65-69 to 46.5% in persons aged 85 years and older. The age-standardized prevalence for overall CIND was 31.9% and for CIND(uc) 19.2%. The prevalences of CIND for the three severity grade were 15.8%, 9.7%, and 6.2% for CDR sum of boxes scores of 0.5, 1-1.5, and >or=2, respectively.


CONCLUSIONS
The prevalence of CIND in community-residing elderly is probably higher than previously reported. The results of this study are useful for assessments of present and future demands for healthcare services.
Choo
Il Han
IH
Department of Neuropsychiatry and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Lee
Dong Young
DY
Lee
Jung Hie
JH
Kim
Ki Woong
KW
Jhoo
Jin Hyeong
JH
Ju
Young-Su
YS
Yoon
Jong Choul
JC
Kim
Shin Gyeom
SG
Ha
Jin
J
Woo
Jong Inn
JI