title: Noise correction on Rician distributed data for fibre orientation estimators.
abstract: New complex tissue microstructure estimators have been presented recently in order to elucidate white matter fibre orientations. Since these algorithms are based on the diffusion-weighted signal profile, the estimations are affected by noise artefacts. The proven robustness of these methods cannot counteract distortions since the statistical Rician behavior has not been taken into account. In this study, two techniques to counteract the noise distortions are presented to improve the fibre orientation estimations. Simulations and in vivo experiments show an improvement in the angular resolution and convergence of the results. One of these strategies represents a good compromise between computational cost and result improvements.
authors.affiliation: Department of Nuclear Medicine, San Raffaele Scientific Institute, 20132 Milan, Italy.
authors.forename: Rafael Alonso
authors.initials: RA
authors.lastname: Clarke
authors.forename: Paola
authors.initials: P
authors.lastname: Scifo
authors.forename: Giovanna
authors.initials: G
authors.lastname: Rizzo
authors.forename: Flavio
authors.initials: F
authors.lastname: Dell'Acqua
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Scotti
authors.forename: Ferruccio
authors.initials: F
authors.lastname: Fazio