title: PI3K enters beta-testing.
abstract: Phosphoinositide-3-OH kinases (PI3K) are critical regulators of cell metabolism, growth, and survival. In a recent publication in Nature, Jia et al. (2008) identify specific functions of the p110beta isoform of PI3K in glucose metabolism, cellular proliferation, and tumorigenesis.
authors.affiliation: Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Shaywitz
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Courtney
authors.forename: Akash
authors.initials: A
authors.lastname: Patnaik
authors.forename: Lewis C
authors.initials: LC
authors.lastname: Cantley