Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.
Plant proteinase inhibitors are involved in the regulation of the activity of many proteinases and, in consequence, in biological processes driven by proteolysis. In this review, we summarize recent results on the activity of native Bauhinia inhibitors and synthetic derivatives. Structural and functional characteristics and the potential therapeutic use of these inhibitors are also discussed.
Oliva
Maria Luiza Vilela
ML
Universidade Federal de São Paulo-Escola Paulista de Medicina, Rua Três de Maio 100, 04044-020 São Paulo, SP, Brazil. olivaml.bioq@epm.br
Sampaio
Uemura Misako
UM