title: New N(4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors.
abstract: Synthesis and enzymatic evaluation of new series of N(4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors for the treatment of Alzheimer's disease are reported.
authors.affiliation: Laboratoire de Chimie Biomoleculaire, Faculte des Sciences Luminy, IBDML-UMR-6216-CNRS, Universite de la Mediterranee, Marseille Cedex, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Laras
authors.forename: C
authors.initials: C
authors.lastname: Garino
authors.forename: J
authors.initials: J
authors.lastname: Dessolin
authors.forename: C
authors.initials: C
authors.lastname: Weck
authors.forename: V
authors.initials: V
authors.lastname: Moret
authors.forename: A
authors.initials: A
authors.lastname: Rolland
authors.forename: J-L
authors.initials: JL
authors.lastname: Kraus