title: Cathepsin D: a cellular roadmap.
abstract: Cathepsin D is a normal and major component of lysosomes, it is found in almost all cells and tissues of mammals. Present review describes different events in cellular life of cathepsin D mainly its biosynthesis, co-translational and posttranslational modifications, targeting to lysosomes and proteolytic processing and maturation within lysosomes.
authors.affiliation: Medical and Natural Sciences Research Centre, University of Tubingen, Ob dem Himmerlreich 7, 72074 Tubingen, Germany.
authors.forename: Nousheen
authors.initials: N
authors.lastname: Zaidi
authors.forename: Andreas
authors.initials: A
authors.lastname: Maurer
authors.forename: Sebastian
authors.initials: S
authors.lastname: Nieke
authors.forename: Hubert
authors.initials: H
authors.lastname: Kalbacher