title: Multiple centrosomes: together they stand, divided they fall.
abstract: Cells with extra centrosomes rely entirely on centrosome clustering mechanisms to assemble a bipolar spindle and to divide in a bipolar fashion. To identify the pathways involved in suppression of multipolarity, Kwon, Godinho, and colleagues (pp. 2189-2203) have set up a genome-wide screen in Drosophila S2 cells. Surprisingly, they found that efficient clustering requires a large number of proteins associated with a variety of cellular functions.
authors.affiliation: Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Department of Oncology, University of Cambridge, Cambridge CB2 0RE, United Kingdom. Fanni.Gergely@cancer.org.uk
authors.forename: Fanni
authors.initials: F
authors.lastname: Gergely
authors.forename: Renata
authors.initials: R
authors.lastname: Basto