Imidazolium salts: a mild reducing and antioxidative reagent.
The concept of directly using imidazolium salts (IMSs) as mild reducing and antioxidative reagents was proposed and investigated. A simple and robust protocol for the synthesis of stable, ultrafine gold nanoparticles has been established using IMSs under mild conditions. IMSs showed remarkably lower toxicity but greater antioxidative power than N-acetyl-L-cystein and (-)-epigallocatechin gallate on HSC-T6 cells. These studies demonstrate that the simple and inexpensive IMSs represent a new type of antioxidant with potential biomedical applications.
Zhao
Lan
L
Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.
Zhang
Chunyan
C
Zhuo
Lang
L
Zhang
Yugen
Y
Ying
Jackie Y
JY