Remifentanil-propofol versus fentanyl-propofol for monitored anesthesia care during hysteroscopy.
OBJECTIVE
To compare the efficacy of remifentanil-propofol with that of fentanyl-propofol for monitored anesthesia care during hysteroscopy.


METHODS
Prospective, randomized study.


METHODS
Operating room and postanesthesia care unit of a university hospital.


METHODS
30 ASA physical status I and II adult patients undergoing hysteroscopic procedures.


METHODS
After propofol infusion, patients received a bolus of remifentanil (group R, 0.5 microg/kg) or fentanyl (group F, 1 microg/kg) 4 minutes before starting the procedure and then received a continuous infusion of remifentanil (group R, 0.05 microg/kg per min) or bolus doses of fentanyl (group F, 0.5 microg/kg).


RESULTS
Patients in group R had lower pain scores than patients in group F (0-0 vs 0-7, P < 0.05) and more stable blood pressures (74 +/- 15 vs 85 +/- 9 mmHg, P < 0.05) one minute after the start of the procedure. However, no differences were observed in other variables (recovery profiles and satisfaction scores).


CONCLUSIONS
Remifentanil seems to be a safe and effective analgesic adjunct for monitored anesthesia care of hysteroscopic surgery.
Ryu
Jung-Hee
JH
Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, South Korea.
Kim
Jae-Hun
JH
Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, South Korea.
Park
Kum-Suk
KS
Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, South Korea.
Do
Sang-Hwan
SH
Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do 463-707, South Korea. Electronic address: shdo@snu.ac.kr.