title: PET-CT in recurrent ovarian cancer: impact on treatment planning.
abstract: BACKGROUND
  Positron emission tomography-computed tomography (PET-CT) is currently not established in the management of recurrent ovarian cancer. Here, its value in diagnosis and therapy planning was evaluated.
  
  
  METHODS
  Seventy patients received PET-CT for suspicion of recurrent ovarian cancer. PET-CT and surgery were reviewed to analyze the accuracy in the diagnosis of recurrence and prediction of full resectability.
  
  
  RESULTS
  PET-CT showed disease relapse in 63 of 70 patients, with full sensitivity and specificity. Thirty cases were operated on. PET-CT indicated full resectability in 24, but in fact only incomplete resection was possible in three cases. Thus sensitivity and specificity for the identification of full resectability were 100% and 66%, respectively. Seven negative results in PET-CT were confirmed by a relapse-free follow-up of 1 year.
  
  
  CONCLUSIONS
  PET-CT offers reliable detection of recurrent ovarian cancer. Although diagnostic accuracy in the prediction of full resectability is limited, surgical planning is improved by identifying sites of intraperitoneal involvement.
authors.affiliation: Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadem, Munich, Germany. Miriam.Lenhard@med.uni-muenchen.de
authors.forename: Miriam S
authors.initials: MS
authors.lastname: Lenhard
authors.forename: Alexander
authors.initials: A
authors.lastname: Burges
authors.forename: Thorsten R C
authors.initials: TR
authors.lastname: Johnson
authors.forename: Petra
authors.initials: P
authors.lastname: Stieber
authors.forename: Carolin
authors.initials: C
authors.lastname: Kümper
authors.forename: Nina
authors.initials: N
authors.lastname: Ditsch
authors.forename: Rainer
authors.initials: R
authors.lastname: Linke
authors.forename: Klaus
authors.initials: K
authors.lastname: Friese