Inhibitory effects of three-component hybrid liposomes containing cationic lipids without drugs on the growth of human renal tumor cells in vitro.
The inhibitory effects of three-component hybrid liposomes (HL) containing cationic lipids on the growth of human renal tumor cells were examined. Fifty percent inhibitory concentration of the three-component HL was remarkably reduced compared with that of dimyristoylphosphatidylcholine liposomes. The induction of apoptosis by the three-component HL without antitumor drugs was obtained for human renal tumor cells for the first time in this study.
Umebayashi
Masayo
M
Graduate Course of Applied Life Science, Sojo University, Ikeda, Kumamoto, Japan.
Matsumoto
Yoko
Y
Ueoka
Ryuichi
R