title: [Perioperative hemodynamics in pheochromocytoma secreting different types of catecholamine].
abstract: OBJECTIVE
  To analyze the characteristics of perioperative hemodynamics in pheochromocytoma secreting different types of catecholamine, and to discuss how to improve the hemodynamics.
  
  
  METHODS
  The clinical data of 202 patients with pheochromocytoma who had received operation were analyzed. Three classification systems were used to divided the patients: they were, firstly, divided into high and low epinephrine secreting groups (E(high) and E(low)) according to the 24 hours urine catecholamine quantitation; secondly, into high and low norepinephrine secreting groups (NE(high) and NE(low)) according to 24-h urine norepinephrine quantitation; and thirdly, into high and low dopamine secreting groups (DA(high) and DA(low)) according to the 24 hours urine dopamine quantitation. Relationship between the characteristics of perioperative hemodynamics and catecholamine secreting types were analyzed.
  
  
  RESULTS
  The highest preoperative systolic blood pressure values of E(high) and NE(high) groups were (201 +/- 40) mm Hg and (205 +/- 38) mm Hg, both significantly higher than those of the E(low) and NE(low) groups [(183 +/- 43) mm Hg, P = 0.003 and (181 +/- 43) mm Hg, P = 0.000]. The range of systolic blood pressure fluctuation during the operation of the E(high) group was 108 +/- 39 mm Hg, significantly larger than that of the E(low) group (91 +/- 33 mm Hg, P = 0.001). The incidence rates of persisting postoperative hypotension of the NE(high) and DA(high) groups were 23.3% (20/86) and 32.7% (17/52) respectively, both higher than those of the NE(low) and DA(low) groups [2.6% (3/116) and 4.0% (6/150) respectively, P = 0.000 and P = 0.000].
  
  
  CONCLUSIONS
  Different characteristics of perioperative hemodynamics are present in pheochromocytoma secreting different types of catecholamines. Patients with highly epinephrine secreting pheochromocytoma are apt to have larger blood fluctuation during the operation. Patients with highly norepinephrine and dopamine secreting pheochromocytoma are apt to suffer from persisting postoperative hypotension.
authors.affiliation: Intensive Care Unit, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Rong-Li
authors.initials: RL
authors.lastname: Yang
authors.forename: Da-Wei
authors.initials: DW
authors.lastname: Liu
authors.forename: Yun
authors.initials: Y
authors.lastname: Long
authors.forename: Yan
authors.initials: Y
authors.lastname: Shi
authors.forename: Wen-Zhao
authors.initials: WZ
authors.lastname: Chai
authors.forename: Han-Zhong
authors.initials: HZ
authors.lastname: Li
authors.forename: Ai-Lun
authors.initials: AL
authors.lastname: Luo
authors.forename: Zheng-Pei
authors.initials: ZP
authors.lastname: Zeng