title: Somatosensory evoked potentials (SEPs) for the evaluation of cervical spondylotic myelopathy: utility of the onset-latency parameters.
abstract: OBJECTIVE
  Peak latencies have been traditionally employed for the evaluation of somatosensory evoked potentials (SEPs). Some authors have argued for the theoretical superiority of the onset latencies, which has never been verified in actual clinical cases. We aimed to investigate the utility of onset-latency parameters of median nerve SEPs in the cervical spondylotic myelopathy (CSM) patients, as well as several other issues concerned with the SEP diagnosis of CSM.
  
  
  METHODS
  We retrospectively enrolled 42 CSM patients and investigated their SEP findings.
  
  
  RESULTS
  The N9o (N9 onset)-P13/14o interval showed the highest sensitivity (83%) followed by N9o-N20o (74%). The sensitivities of corresponding peak latency parameters were lower (62% and 33%). The amplitude of the lower cervical N13 also showed the highest sensitivity (83%). The sensitivity of tibial nerve SEPs examined in 21 patients was lower (71%) than that of median nerve SEPs (90%). When clinical signs alone were used as the gold standard, the sensitivity of median SEPs was 90% whereas that of MRI was 88%.
  
  
  CONCLUSIONS
  Higher diagnostic yield of onset-latency parameters of median nerve SEPs has been documented in CSM.
  
  
  CONCLUSIONS
  SEPs are useful in the diagnosis of CSM having equal sensitivity and probably higher specificity than MRI.
authors.affiliation: Department of Neurology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 1738605, Japan.
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Nakai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sonoo
authors.forename: Teruo
authors.initials: T
authors.lastname: Shimizu