Restless legs syndrome: an early manifestation of Huntington's disease?
BACKGROUND
Far from being uniform, Huntington's disease (HD)'s phenotype encompasses a large variety of motor and non-motor symptoms which occur in various combinations in individual patients.


OBJECTIVE
To describe an unusual association between restless legs syndrome (RLS) and HD.


RESULTS
We report a patient with an atypical presentation of genetically demonstrated HD, who developed typical RLS a few years prior to and during the course of HD. Common causes of RLS were excluded and the polysomnography confirmed frequent and severe periodic limb movements during sleep and while awake.


CONCLUSIONS
We propose RLS as an uncommon but early feature of HD in some patients, and suggest adding HD to the already long list of RLS secondary to neurodegenerative conditions.
Savva
E
E
Department of Neurology, Geneva University Hospitals and Medical School, Switzerland. elena.sava@hcuge.ch
Schnorf
H
H
Burkhard
P R
PR