Biophysical and biorheological studies on the precursor cells at different stages.
Splenic erythroblasts were obtained from mice during the acute disease caused by anemiainducing virus (FVA). They were cultured in a medium containing EPO, BSA and so on. We studied their biomechanical and hemorheological behavior after 12 h, 24 h and 48 h. The results showed obvious changes in their electrophoretic mobility, osmotic fragility, membrane fluidity and membrane viscoelastic properties with the development of erythroblast. The changes were associated with the interactions of the protein and lipid and the elements of the membrane.
Wang
Jinhua
J
Department of Medical Physics, Basic Medical School of Peking University, 100083, Beijing, China.
Sun
Dagong
D
Yao
Weijuan
W
Zeng
Zhu
Z
Yan
Zongyi
Z
Wen
Zongyao
Z