title: [Evaluation of peritumoral brain edema in intracranial meningiomas using CT perfusion imaging].
abstract: OBJECTIVE
  To evaluate the perfusion characteristics of the peritumoral brain edema of intracranial meningiomas using 16-slice spiral CT perfusion imaging.
  
  
  METHODS
  Dynamic contrast-enhanced single-location sequence CT scan was performed in 19 patients with intracranial meningiomas and peritumoral brain edema. The regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV) and the mean transit time (MTT) were calculated for the peritumoral brain edema and the contralateral white matter and comparatively analyzed.
  
  
  RESULTS
  The rCBF and rCBV in the peritumoral brain edema were significantly lower than those of the contralateral white matter in patients with meningiomas (rCBF: 14.26-/+7.44 vs 26.92-/+15.71 ml/100 g tissue.min, P<0.05; rCBV: 0.96-/+0.35 vs 2.47-/+1.69 ml/100 g tissue, P<0.05). But the MTT showed no significant difference between the peritumoral brain edema and the contralateral white matter (P>0.05).
  
  
  CONCLUSIONS
  The rCBF and rCBV are significantly lowered in the peritumoral brain edema in comparison with those of the contralateral white matter. Vascular compression by the edema fluid may have a major effect on the tissue blood flow and blood volume.
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China. yangzhilin@tom.com
authors.forename: Zhi-lin
authors.initials: ZL
authors.lastname: Yang
authors.forename: Yi-quan
authors.initials: YQ
authors.lastname: Ke
authors.forename: Ru-xiang
authors.initials: RX
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Peng