[Effects of radiation injury on peripheral blood and liver NO concentration in mice].
OBJECTIVE
To study the effect of radiation injury on nitric oxide (NO) concentration in mouse peripheral blood and liver.


METHODS
NIH mice were subjected to gamma-ray exposure at 9.0 Gy and transferred immediately in room temperature condition. NO concentrations in the liver and peripheral blood were examined before and at different time points after the exposure.


RESULTS
Compared to that before exposure, NO concentration in the peripheral blood and liver significantly increased after gamma-ray exposure. NO concentration in the peripheral blood began to increase 3 h after the exposure, but that in the liver increased till 6 h after the exposure.


CONCLUSIONS
Radiation can cause the increase of NO concentration in the peripheral blood and liver, but different tissues may exhibit different response intensities to radiation.
Ou
Cheng-shan
CS
Department of Radiation Medicine, School of Public Hygiene and Tropical Medicine, Southern Medical University, Guangzhou, China. ocshlm@fimmu.com
Jiang
Li-hong
LH
Ye
Qing
Q
Zhou
Mei-juan
MJ