Phase-shift presaturation for water peak suppression in biomolecular NMR experiments.
The phase-shift presaturation technique for water suppression is further improved with effective phase cycling. In the two-dimensional NMR COSY, NOESY and HMQC experiments of biosamples, the water suppression factor reaches the order of 10(-6), making it possible to detect(13)C NMR signals in extremely diluted (2 mmol/L) aqueous solutions.
Mao
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X
Chinese Academy of Sciences, Wuhan, China.
Ye
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C