title: [Brimonidine intoxication in paediatrics. A presentation as intracranial hypertension syndrome].
abstract: BACKGROUND
  Brimonidine is an extremely lipophilic drug which is absorbed very well through the cornea and thus crosses the blood-brain barrier. This is very important for any potential toxic effects on the CNS.
  
  
  OBJECTIVE
  To show the adverse effects of brimonidine and advise the need for caution in its use in the paediatric population.
  
  
  CONCLUSIONS
  Brimonidine is prohibited from use in toddlers and infants. Its adverse effects can be severe or lethal. It should be suspected in treated patients with compatible symptoms in whom organic disease has been ruled out. We must stop the use of brimonidine and adopt support measures.
authors.affiliation: Servicio de Pediatría. Hospital Universitario Infantil Virgen del Rocío. Sevilla. España. Drlolo13@hotmail.com
authors.forename: M A
authors.initials: MA
authors.lastname: Fernández Fernández
authors.forename: M D
authors.initials: MD
authors.lastname: Morillo Rojas
authors.forename: M A
authors.initials: MA
authors.lastname: Ribó Golovart
authors.forename: A
authors.initials: A
authors.lastname: Ribó Marco