Identification of a new cytotoxic biflavanone from Selaginella doederleinii.
A new biflavanone, 2,2'',3,3''-tetrahydrorobustaflavone 7,4',7''-trimethyl ether (1) was isolated from the whole plant of Selaginella doederleinii HIERON. (Selaginellaceae) together with the known biflavonoid, robustaflavone 7,4',7''-trimethyl ether (2) as the cytotoxic constituents against the three human cancer cell lines, HCT, NCI-H358, and K562. The structure of the new compound 1 was elucidated by spectral analysis including various 1D- and 2D-NMR experiments.
Lee
Na-Youn
NY
College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University, Seoul, Korea.
Min
Hye-Young
HY
Lee
Jun
J
Nam
Joo-Won
JW
Lee
Yoo-Jin
YJ
Han
Ah-Reum
AR
Wiryawan
Adam
A
Suprapto
Wahyu
W
Lee
Sang Kook
SK
Seo
Eun-Kyoung
EK