The ultrastructure of cultures of chick embryo fibroblasts containing togavirus-like particles.
The ultrastructural appearance of fibroblasts cultured from specific pathogen-free chick embryos is described. These cells contained virus-like particles approximately 50 nm in diameter which accumulated in cytoplasmic vacuoles. In their size, morphology and mode of replication these particles closely resemble viruses in the genus Pestivirus, family Togaviridae.
Frazier
J A
JA
Institute for Animal Disease Research, Houghton Laboratory, Houghton, Huntingdon, Cambridgeshire, England.
Milne
B S
BS
Farmer
H
H