title: Auditory interhemispheric transfer in relation to patterns of partial agenesis and hypoplasia of the corpus callosum in spina bifida meningomyelocele.
abstract: Spina bifida meningomyelocele with hydrocephalus (SBM) is commonly associated with anomalies of the corpus callosum (CC). We describe MRI patterns of regional CC agenesis and relate CC anomalies to functional laterality based on a dichotic listening test in 90 children with SBM and 27 typically developing controls. Many children with SBM (n = 40) showed regional CC anomalies in the form of agenesis of the rostrum and/or splenium, and a smaller number (n = 20) showed hypoplasia (thinning) of all CC regions (rostrum, genu, body, and splenium). The expected right ear advantage (REA) was exhibited by normal controls and children with SBM having a normal or hypoplastic splenium. It was not shown by children with SBM who were left handed, missing a splenium, or had a higher level spinal cord lesion. Perhaps the right hemisphere of these children is more involved in processing some aspects of linguistic stimuli.
authors.affiliation: Department of Psychology, University of Houston, Houston, Texas 77204-5052, USA. jhannay@uh.edu
authors.forename: H Julia
authors.initials: HJ
authors.lastname: Hannay
authors.forename: Amy
authors.initials: A
authors.lastname: Walker
authors.forename: Maureen
authors.initials: M
authors.lastname: Dennis
authors.forename: Larry
authors.initials: L
authors.lastname: Kramer
authors.forename: Susan
authors.initials: S
authors.lastname: Blaser
authors.forename: Jack M
authors.initials: JM
authors.lastname: Fletcher