[Brimonidine intoxication in paediatrics. A presentation as intracranial hypertension syndrome].
BACKGROUND
Brimonidine is an extremely lipophilic drug which is absorbed very well through the cornea and thus crosses the blood-brain barrier. This is very important for any potential toxic effects on the CNS.


OBJECTIVE
To show the adverse effects of brimonidine and advise the need for caution in its use in the paediatric population.


CONCLUSIONS
Brimonidine is prohibited from use in toddlers and infants. Its adverse effects can be severe or lethal. It should be suspected in treated patients with compatible symptoms in whom organic disease has been ruled out. We must stop the use of brimonidine and adopt support measures.
Fernández Fernández
M A
MA
Servicio de Pediatría. Hospital Universitario Infantil Virgen del Rocío. Sevilla. España. Drlolo13@hotmail.com
Morillo Rojas
M D
MD
Ribó Golovart
M A
MA
Ribó Marco
A
A