Junction probes - sequence specific detection of nucleic acids via template enhanced hybridization processes.
Junction probe nucleic acid detection technology allows the amplified sensing of analytes at isothermal conditions. The addition of a second dimension to detection probes permits the use of cheap commercially available DNA processing enzymes such as restriction endonucleases to detect single nucleotide polymorphisms, SNPs.
Nakayama
Shizuka
S
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA.
Yan
Lei
L
Sintim
Herman O
HO