Pathological and immunological studies on goose embryos and one-day-old goslings experimentally infected with a Mycoplasma strain of goose origin.
Goose embryos and one-day-old goslings were inoculated either on the 10th or 20th day of incubation into the yolk sac or into the air sac or intranasally, with Mycoplasma strain 1220 isolated from a goose. Subsequently morphological, immunological and microbiological * changes were determined. Infection during incubation resulted in an acute serous inflammation of the chorioallantoic membrane, a diffuse, heterophil granulocytic interstitial hepatitis and a bronchopneumonia. One-day-old goslings developed lympho-histiocytic infiltrations of the productive type in the interstitium of the lungs, the walls of the major bronchi, the mucous membrane of the nasal conchae and in the visceral pleura. Blood lymphocytes of 28-day-old embryos infected at 10 days of incubation recognised and specifically reacted with the antigen in immunorosette formation and lymphocyte transformation tests. However, after hatching the antigen-recognising capacity of lymphocytes decreased, and had become considerably reduced by day 30 after hatching. No antibodies were demonstrable in the indirect haemagglutination test.
Stipkovits
L
L
Veterinary Medical Research Institute of the Hungarian Academy of Sciences, Budapest, Hungary.
Varga
Z
Z
Glavits
R
R
Ratz
F
F
Molnar
E
E