title: Hereditary neuropathy with liability to pressure palsies: case report and discussion.
abstract: Hereditary neuropathy with liability to pressure palsies (HNPP) is an uncommon diagnosis that should be considered in patients with multiple compressive neuropathies. We present the case of a woman who presented with bilateral hand numbness and weakness. Electrodiagnostic testing revealed bilateral carpal tunnel syndrome, bilateral ulnar neuropathy at the elbow, left peroneal neuropathy at the fibular head, and a primarily demyelinating generalized sensorimotor neuropathy. Subsequent genetic testing identified a deletion at chromosome 17p11.2 to confirm the diagnosis of HNPP. Treatment of this largely self-limiting disease is controversial, and this patient suffered minimal disability with treatment including splinting and surgical releases.
authors.affiliation: Department of Physiatry, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA. grossmanm@hss.edu
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Grossman
authors.forename: Joseph
authors.initials: J
authors.lastname: Feinberg
authors.forename: Edward F
authors.initials: EF
authors.lastname: DiCarlo
authors.forename: Sherri B
authors.initials: SB
authors.lastname: Birchansky
authors.forename: Scott W
authors.initials: SW
authors.lastname: Wolfe