A sweet spot for the bariatric surgeon.
While gastric bypass surgery remains popular as the only treatment for morbid obesity with curative potential, the molecular mechanisms underpinning its immediate metabolic benefits remain unclear. New work in this issue (Troy et al., 2008) suggests intestinal glucose production sensed by afferent nerve fibers surrounding the portal vein may be key.
Perez-Tilve
Diego
D
Departments of Psychiatry and Medicine, Obesity Research Centre, University of Cincinnati School of Medicine, Cincinnati, OH 45267, USA.
D'Alessio
David A
DA
Tschöp
Matthias H
MH