title: Gold- and silver-mediated cycloisomerizations of N-propargylamides.
abstract: Substituted N-propargylamides have proven to be valuable substrates for alkyne-activated cycloisomerization reactions. N-Tosyl- N'-propargylurea underwent reaction with AuCl 3 to give the corresponding dihydroimidazolone, while N-propargyl-3-oxobutanamides and esters were used to construct furanyl fused pyrrolidinones and dihydrofuranones via Ag(I)-mediated alkyne activation.
authors.affiliation: Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Guido
authors.initials: G
authors.lastname: Verniest
authors.forename: Albert
authors.initials: A
authors.lastname: Padwa