title: [Assessment of different homeostatic methods used in laparoscopic intramural myomectomy].
abstract: OBJECTIVE
  To explore the safe and effective method of hemostasis in laparoscopic hysteromyomectomy (LM).
  
  
  METHODS
  Two hundred and eighty women with symptomatic uterine intramural fibroids undergoing LM were assigned to 4 groups, Group A undergoing fibroid pedicle ligation, Group B injected with 12 IU diluted vasopressin around the myoma, Group C injected with 20 IU oxytocin combined with pedicle ligation, and Group D injected with vasopressin combined with pedicle ligation. The operation time, amount of blood loss, operative complications, bowel deflation, post-operative hemoglobin dropping, and length of hospital stay were compared.
  
  
  RESULTS
  The amounts of blood loss of Groups A and C were (171 +/- 146) ml and (184 +/- 140) ml, both significantly higher than those of Groups B and D [(115 +/- 70) ml and (106 +/- 73) ml, both P < 0.01]. The length of hospital stay of Group D was (2.9 +/- 0.5) d, significantly shorter than those of Groups A, B, and C [(3.1 +/- 0.7) d, (3.6 +/- 0.8) d, and (3.3 +/- 0.7) d, all P < 0.05]. The bowel deflation time of Group D was (20 +/- 6) h, significantly shorter than those of the Groups A, B, and C [(26 +/-) h, (25 +/- 7) h, and (25 +/- 8) h respectively, all P < 0.05]. The post-operative hemoglobin dropping of group D was (1.1 +/- 0.9) g/L, significantly less than those of Groups A, B, and C [(1.5 +/- 1.0), (1.4 +/- 0.8), and (1.2 +/- 0.7) g/L respectively, all P < 0.05].
  
  
  CONCLUSIONS
  Vasopressin (12 IU) injection around the myoma is a simple, effective, and safe homeostatic procedure during LM. Pedicle ligation can reduce advanced post-operative bleeding post-operation.
authors.affiliation: Department of Gynecology and Obstetrics, Sir Run Run Shaw Hospital, Zhejiang University Medical College, Hangzhou 310016, China. Linna73@263.com
authors.forename: Xiao-Na
authors.initials: XN
authors.lastname: Lin
authors.forename: Song-Ying
authors.initials: SY
authors.lastname: Zhang
authors.forename: Su-Hua
authors.initials: SH
authors.lastname: Fang
authors.forename: Min-Zhen
authors.initials: MZ
authors.lastname: Wang
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Lou