Maternal, prenatal and perinatal characteristics and first trimester maternal serum hormone concentrations.
In uncomplicated pregnancies, first trimester androgen, oestrogen and prolactin concentrations were higher in nulliparous (n=160) than parous (n=260) mothers. Androgens and estrogens were higher in younger than older mothers. These data are consistent with elevated hormone concentrations mediating the breast cancer protection from a first pregnancy and pregnancies occurring at younger ages.
Troisi
R
R
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, 6120 Executive Boulevard, Rockville, MD 20892-7246, USA. troisir@mail.nih.gov
Hoover
R N
RN
Thadhani
R
R
Hsieh
C-C
CC
Sluss
P
P
Ballard-Barbash
R
R
Potischman
N
N