[Tourette syndrome. Genetics, neuroanatomy and neurotransmitters].
The etiology and pathophysiology of Tourette syndrome (TS) have not yet been clarified. Despite inconsistencies in the literature, some conclusions can be drawn on genetics, neuroanatomy and neurotransmitters. The inheritance of TS is unknown; the etiology seems to be polygenic. The basal ganglia are probably smaller in patients with TS. A dysfunction in the dopaminergic pathway causes tics. ADHD results from a decreased concentration of dopamine and an increased concentration of noradrenaline. OCD is caused by a dysfunction in serotonin and probably dopamine.
Debes
Nanette M M Mol
NM
Glostrup Hospital, Børneafdeling L, Glostrup. nanettemol@hotmail.com
Skov
Liselotte
L
Hjalgrim
Helle
H