Seizures associated with ertapenem use in patients with CNS disorders and renal insufficiency.
Three patients presented seizures during ertapenem therapy. They were classified as probably-related in 1 case and as possible-related in the others. Convulsions appeared after 1 week of therapy at usual doses with 1 or 2 events, and were observed only among patients with CNS disorders and renal insufficiency.
Fica
Alberto E
AE
Seccion de Infectologia, Departamento de Medicina, Hospital Clinico Universidad de Chile, Santos Dumont 999, Independencia,Santiago, Chile. afica@redclinicauchile.cl
Abusada
Nancy J
NJ