Spindly attachments.
The attachment of chromosomes to spindle microtubules during mitosis is a delicate and intricate process on which eukaryotic cells critically depend to maintain their ploidy. In this issue of Genes & Development, Gassmann and colleagues (pp. 2385-2399 present an analysis of the recently discovered Spindly/SPDL-1 protein that casts new lights onto the attachment process and the way it relates to the control of cell cycle progression.
Civril
Filiz
F
Department of Experimental Oncology, European Institute of Oncology, I-20139 Milan, Italy.
Musacchio
Andrea
A