title: Success of ampicillin plus ceftriaxone rescue therapy for a relapse of Enterococcus faecalis native-valve endocarditis and in vitro data on double beta-lactam activity.
abstract: We report a patient with Enterococcus faecalis native-valve endocarditis who relapsed after 4 weeks of treatment with ampicillin plus gentamicin. The relapse was cured with ampicillin plus ceftriaxone, which was introduced after gentamicin-induced acute renal failure. This double beta-lactam combination showed a bactericidal effect in time-killing curve studies.
authors.affiliation: Infectious Diseases Service, Hospital Clinic, Helios Building, Desk no. 26, Villarroel 170, 08036 Barcelona, Spain. jmmiro@ub.edu
authors.forename: Jose M
authors.initials: JM
authors.lastname: Miro
authors.forename: Carlos
authors.initials: C
authors.lastname: Cervera
authors.forename: Cristina
authors.initials: C
authors.lastname: Garcia-de-la-Maria
authors.forename: Ana
authors.initials: A
authors.lastname: Del Rio
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Armero
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Mestres
authors.forename: Jose M
authors.initials: JM
authors.lastname: Grau
authors.forename: Francesc
authors.initials: F
authors.lastname: Marco
authors.forename: Asuncion
authors.initials: A
authors.lastname: Moreno