Diagnostic challenges of central nervous system tuberculosis.
Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California Encephalitis Project. Atypical features (encephalitic symptoms, rapid onset, age) and diagnostic challenges (insensitive cerebrospinal fluid [CSF] TB PCR result, elevated CSF glucose levels in patients with diabetes, negative result for tuberculin skin test) complicated diagnosis.
Christie
Laura J
LJ
Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California 94804, USA. laura.christie@cdph.ca.gov
Loeffler
Ann M
AM
Honarmand
Somayeh
S
Flood
Jennifer M
JM
Baxter
Roger
R
Jacobson
Susan
S
Alexander
Rick
R
Glaser
Carol A
CA