Ampullary adenocarcinoma - differentiation matters.
The periampullary region gives rise to two main subtypes of adenocarcinoma that show either pancreatobiliary or intestinal differentiation. New data demonstrates that the histological subtype - more so than the anatomical location - is an important independent prognostic factor. This fuels the discussion about maintaining ampullary cancer as a separate entity.
Schirmacher
Peter
P
Department of Surgery, University Hospital, Im Neuenheimer Feld, 69120 Heidelberg, Germany. Peter.Schirmacher@med.uni-heidelberg.de
Büchler
Markus W
MW