title: Stereoselective synthesis of the rocaglamide skeleton via a silyl vinylketene formation/[4 + 1] annulation sequence.
abstract: The tricyclic core of the cyclopentabenzofurans has been prepared in an efficient and stereoselective manner utilizing an intramolecular silyl vinylketene formation/[4 + 1] annulation sequence. This novel approach affords the ABC ring system where the adjacent phenyl and aryl substituents of the C ring have the required cis relationship.
authors.affiliation: Department of Chemistry and Chemical Biology, Indiana University-Purdue University, Indianapolis, Indiana 46202, USA.
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Giese
authors.forename: William H
authors.initials: WH
authors.lastname: Moser