Experimental infections of one-day-old poults with turkey isolates of infectious bursal disease virus.
One-day-old poults infected with infectious bursal disease virus of turkey origin (TIBDV) suffered a prolonged (3 to 4 week) suppression of the cellular immune response and a decrease in the plasma cell population of the Harderian gland. By immunofluorescent techniques, IBDV was demonstrated to persist for 7 days post infection. Antigen was demonstrated in bursal epithelium at the apex of the plica and was never seen in the follicle or cortex. Infection with TIBDV generally presented as a silent disease.
Nusbaum
K E
KE
Department of Microbiology, College of Veterinary Medicine, Auburn University, Alabama, USA.
Lukert
P D
PD
Fletcher
O J
OJ