PET-CT in recurrent ovarian cancer: impact on treatment planning.
BACKGROUND
Positron emission tomography-computed tomography (PET-CT) is currently not established in the management of recurrent ovarian cancer. Here, its value in diagnosis and therapy planning was evaluated.


METHODS
Seventy patients received PET-CT for suspicion of recurrent ovarian cancer. PET-CT and surgery were reviewed to analyze the accuracy in the diagnosis of recurrence and prediction of full resectability.


RESULTS
PET-CT showed disease relapse in 63 of 70 patients, with full sensitivity and specificity. Thirty cases were operated on. PET-CT indicated full resectability in 24, but in fact only incomplete resection was possible in three cases. Thus sensitivity and specificity for the identification of full resectability were 100% and 66%, respectively. Seven negative results in PET-CT were confirmed by a relapse-free follow-up of 1 year.


CONCLUSIONS
PET-CT offers reliable detection of recurrent ovarian cancer. Although diagnostic accuracy in the prediction of full resectability is limited, surgical planning is improved by identifying sites of intraperitoneal involvement.
Lenhard
Miriam S
MS
Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadem, Munich, Germany. Miriam.Lenhard@med.uni-muenchen.de
Burges
Alexander
A
Johnson
Thorsten R C
TR
Stieber
Petra
P
Kümper
Carolin
C
Ditsch
Nina
N
Linke
Rainer
R
Friese
Klaus
K