title: Automatic model-based segmentation of the heart in CT images.
abstract: Automatic image processing methods are a prerequisite to efficiently analyze the large amount of image data produced by computed tomography (CT) scanners during cardiac exams. This paper introduces a model-based approach for the fully automatic segmentation of the whole heart (four chambers, myocardium, and great vessels) from 3-D CT images. Model adaptation is done by progressively increasing the degrees-of-freedom of the allowed deformations. This improves convergence as well as segmentation accuracy. The heart is first localized in the image using a 3-D implementation of the generalized Hough transform. Pose misalignment is corrected by matching the model to the image making use of a global similarity transformation. The complex initialization of the multicompartment mesh is then addressed by assigning an affine transformation to each anatomical region of the model. Finally, a deformable adaptation is performed to accurately match the boundaries of the patient's anatomy. A mean surface-to-surface error of 0.82 mm was measured in a leave-one-out quantitative validation carried out on 28 images. Moreover, the piecewise affine transformation introduced for mesh initialization and adaptation shows better interphase and interpatient shape variability characterization than commonly used principal component analysis.
authors.affiliation: Philips Research Europe-Aachen, X-ray ImagingSystems, Weisshausstr. 2, 52062 Aachen, Germany. olivier.ecabert@philips.com
authors.forename: Olivier
authors.initials: O
authors.lastname: Ecabert
authors.forename: Jochen
authors.initials: J
authors.lastname: Peters
authors.forename: Hauke
authors.initials: H
authors.lastname: Schramm
authors.forename: Cristian
authors.initials: C
authors.lastname: Lorenz
authors.forename: Jens
authors.initials: J
authors.lastname: von Berg
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Walker
authors.forename: Mani
authors.initials: M
authors.lastname: Vembar
authors.forename: Mark E
authors.initials: ME
authors.lastname: Olszewski
authors.forename: Krishna
authors.initials: K
authors.lastname: Subramanyan
authors.forename: Guy
authors.initials: G
authors.lastname: Lavi
authors.forename: Jürgen
authors.initials: J
authors.lastname: Weese