title: Modeling of human colonic blood flow for a novel artificial anal sphincter system.
abstract: A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vascularity of the human colon.
authors.affiliation: School of Electronics, Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. zanpeng@sjtu.edu.cn
authors.forename: Peng
authors.initials: P
authors.lastname: Zan
authors.forename: Guo-zheng
authors.initials: GZ
authors.lastname: Yan
authors.forename: Hua
authors.initials: H
authors.lastname: Liu