Association between sleep and physical function in older men: the osteoporotic fractures in men sleep study.
OBJECTIVE
To determine whether sleep quality is associated with physical function in older men.


METHODS
Cross-sectional.


METHODS
Six U.S. centers.


METHODS
Two thousand eight hundred sixty-two community-dwelling men.


METHODS
Total hours of nighttime sleep (TST), wake after sleep onset (WASO), sleep latency (SL), and sleep efficiency (SE) measured using actigraphy; sleep stage distribution, respiratory disturbance index (RDI), and hypoxia measured using polysomnography; measures of physical function: grip strength, walking speed, chair stand, and narrow walk.


RESULTS
In age-adjusted models, <6 or >8 hours TST, SE less than 80%, WASO of 90 minutes or longer, RDI of 30 or greater, and hypoxia were associated with poorer physical function. (Mean grip strength was 2.9% lower and mean walking speed was 4.3% lower in men with WASO >or=90 minutes than men with WASO <90 minutes.) After adjusting for potential covariates, differences in grip strength and walking speed remained significantly associated with WASO of 90 minutes or longer, SE less than 80%, and hypoxia but not with TST or RDI of 30 or greater.


CONCLUSIONS
Greater sleep fragmentation and hypoxia are associated with poorer physical function in older men.
Dam
Thuy-Tien L
TT
Department of Medicine, University of California at San Diego, La Jolla, California, USA. tldam@ucsd.edu
Ewing
Susan
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Ancoli-Israel
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Ensrud
Kristine
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Redline
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Stone
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