PI3K enters beta-testing.
Phosphoinositide-3-OH kinases (PI3K) are critical regulators of cell metabolism, growth, and survival. In a recent publication in Nature, Jia et al. (2008) identify specific functions of the p110beta isoform of PI3K in glucose metabolism, cellular proliferation, and tumorigenesis.
Shaywitz
Adam J
AJ
Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Courtney
Kevin D
KD
Patnaik
Akash
A
Cantley
Lewis C
LC