title: [MLST typing of Streptococcus suis isolated from clinical patients in Guangdong Province in 2005].
abstract: Intensive surveillance of human S.suis infection was carried out in July and August of 2005 in Guangdong Province, which coincided with the Sichuan outbreak. Five isolated cases of human infections were identified during this period, from which 5 S. suis serotype 2 isolates were recovered. MLST analysis showed that these 5 isolates shared identical sequences of 6 MLST housekeeping genes except for one point mutation found within the thrA gene fragment, a neutral mutation (TTA to TTG) in the third nucleotide (360 nt) of the codon for leucine. MLST analysis identified 2 sequence types in the Guangdong sporadic infection. Three Guangdong isolates L-SS002, L-SS003 and L-SS005 belonged to ST7, while the other two isolates L-SS004 and L-SS006 belonged to ST1, but they all belonged to ST1 clonal complex. This finding represents a striking feature that differs from the Sichuan outbreak caused by a single ST7 SS2 clone. The 3 isolates of ST7 were probably imported from Sichuan Province, while the origin of the other 2 isolates of ST1 still remain to be clarified.
authors.affiliation: Department of Biochemistry and Molecular Biology, Sun Yat-sen University, Guangzhou, China. melkom@163.com
authors.forename: Hong-min
authors.initials: HM
authors.lastname: Wang
authors.forename: Chang-wen
authors.initials: CW
authors.lastname: Ke
authors.forename: Wu-bin
authors.initials: WB
authors.lastname: Pan
authors.forename: Bi-xia
authors.initials: BX
authors.lastname: Ke
authors.forename: Jing-diao
authors.initials: JD
authors.lastname: Chen
authors.forename: Xiao-ling
authors.initials: XL
authors.lastname: Deng
authors.forename: Mei-zhen
authors.initials: MZ
authors.lastname: Liu
authors.forename: Guo-ren
authors.initials: GR
authors.lastname: Chen
authors.forename: Xing-fen
authors.initials: XF
authors.lastname: Yang
authors.forename: Zhen-yu
authors.initials: ZY
authors.lastname: Zhu