[Self-limitation of inflammatory T-cell responses. Help to self-help as a therapeutic concept].
Regulatory T cells are in the focus of research on autoimmunity. However, recent findings suggest that pro-inflammatory T(H)1 cells themselves exert important immunoregulatory functions. This physiological self-limiting mechanism holds great promise for therapeutic interventions.
Rutz
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Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin.
Scheffold
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A