title: Chemical constituents from the leaves of Manglietia phuthoensis and their effects on osteoblastic MC3T3-E1 cells.
abstract: Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated from the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experiments. Among them, compounds 2 and 5 significantly (p<0.05) increased the growth and differentiation of osteoblastic MC3T3-E1 cells in vitro.
authors.affiliation: Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, Viet, Nghiado, Caugiay, Hanoi, Vietnam.
authors.forename: Phan Van
authors.initials: PV
authors.lastname: Kiem
authors.forename: Mai Dinh
authors.initials: MD
authors.lastname: Tri
authors.forename: Le Vo Dinh
authors.initials: le VD
authors.lastname: Tuong
authors.forename: Nguyen Huu
authors.initials: NH
authors.lastname: Tung
authors.forename: Nguyen Ngoc
authors.initials: NN
authors.lastname: Hanh
authors.forename: Tran Hong
authors.initials: TH
authors.lastname: Quang
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Cuong
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
authors.forename: Eun-Mi
authors.initials: EM
authors.lastname: Choi
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim