title: Clinical significance of urodynamic analysis in patients with benign prostatic enlargement complicated with diabetes mellitus.
abstract: OBJECTIVE
  To compare the bladder dysfunction associated with benign prostatic enlargement (BPE) in patients with and without diabetes mellitus (DM) by urodynamic study.
  
  
  METHODS
  The records of 166 first-visit BPE patients were reviewed. Patients were divided into two groups: concomitant group (CG) - 74 patients with BPE complicated with DM, and single group (SG) - 92 isolated BPE patients. Urodynamic findings of the two groups were analyzed.
  
  
  RESULTS
  In the clinical data, increased postvoiding residual urine volume (PVR) appeared more often in CG (p < 0.05). In the urodynamic findings, significantly higher maximum cystometric capacity (MCC), incidence of impaired bladder sensation, bladder compliance and detrusor overactivity existed in CG (p < 0.05). In addition, the maximum detrusor pressure during voiding (Pdet(max)) and the incidence of bladder outlet obstruction (BOO) were significantly higher in SG (p < 0.05).
  
  
  CONCLUSIONS
  Impaired bladder function is more severe in patients with BPE complicated with DM than those isolated BPE patients. Urodynamic study can provide objective data on diagnosis of voiding dysfunction in BPE patients with and without DM, and it is helpful for doctors to choose better clinical intervention.
authors.affiliation: Department of Urology, Qilu Hospital of Shandong University, Jinan, China.
authors.forename: Keqin
authors.initials: K
authors.lastname: Zhang
authors.forename: Zhishun
authors.initials: Z
authors.lastname: Xu
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Haixin
authors.initials: H
authors.lastname: Wang
authors.forename: Dongqing
authors.initials: D
authors.lastname: Zhang
authors.forename: Benkang
authors.initials: B
authors.lastname: Shi