title: Inhibition of lipid peroxidation by extracts/subfractions of Chickrassy (Chukrasia tabularis A. Juss.).
abstract: Polyphenols and polyphenol-rich fractions of plants have been reported to have protective effects against lipid peroxidation, most probably by serving as scavengers of free radicals and/or by chelating metal ions. In the present study, the effect of different extracts/subfractions of Chickrassy (Chukrasia tabularis) on peroxyl radical mediated damage to the polyunsaturated fatty acids was investigated. Liver homogenate was used as experimental material. The production of malondialdehyde served as a marker of lipid peroxidation and oxidative stress. It was observed that polyphenol-rich fractions, particularly the ethyl acetate fractions of bark and leaves, showed the highest protective activity of 83.02% and 88.62% inhibition, respectively. This study will help in knowing the scientific validation of this plant, for its use in ayurvedic formulations.
authors.affiliation: Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar-143005, Punjab, India.
authors.forename: Rajbir
authors.initials: R
authors.lastname: Kaur
authors.forename: Tarunpreet Singh
authors.initials: TS
authors.lastname: Thind
authors.forename: Bikram
authors.initials: B
authors.lastname: Singh
authors.forename: Saroj
authors.initials: S
authors.lastname: Arora