title: Steroidal saponins from the roots of Smilax aspera subsp. mauritanica.
abstract: Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 microg/ml, respectively) whereas the other compounds were inactive.
authors.affiliation: Laboratoire de Pharmacognosie, Unité UMIB UPRES-EA, Faculté de Pharmacie, Université de Bourgogne, Dijon Cedex, France.
authors.forename: Zineddine
authors.initials: Z
authors.lastname: Belhouchet
authors.forename: Marc
authors.initials: M
authors.lastname: Sautour
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Marie-Aleth
authors.initials: MA
authors.lastname: Lacaille-Dubois