Sand flies, Leishmania, and transcriptome-borne solutions.
Sand fly-parasite and sand fly-host interactions play an important role in the transmission of leishmaniasis. Vector molecules relevant for such interactions include midgut and salivary proteins. These potential targets for interruption of propagation of Leishmania parasites have been poorly characterized. Transcriptomic analysis has proven to be an effective tool for identification of new sand fly molecules, providing exciting new insights into vector-based control strategies against leishmaniasis.
Oliveira
Fabiano
F
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Jochim
Ryan C
RC
Valenzuela
Jesus G
JG
Kamhawi
Shaden
S