title: Bayesian characterization of external anal sphincter muscles using quantitative electromyography.
abstract: OBJECTIVE
  Based on the analysis of electromyographic (EMG) data muscles are often characterized as normal or affected by a neuromuscular disease process. The objective of this work was to compare the accuracy of Bayesian muscle characterization to conventional means and outlier analysis of motor unit potential (MUP) feature values.
  
  
  METHODS
  Quantitative MUP data from the external anal sphincter muscles of control subjects and patients were used to compare the sensitivity, specificity, and accuracy of the methods under examination.
  
  
  RESULTS
  The results demonstrated that Bayesian muscle characterization achieved similar accuracy to combined means and outlier analysis. Thickness and number of turns were the most discriminative MUP features for characterizing the external anal sphincter (EAS) muscles studied in this work.
  
  
  CONCLUSIONS
  Although, Bayesian muscle characterization achieved similar accuracy to combined means and outlier analysis, Bayesian muscle characterization can facilitate the determination of "possible", "probable", or "definite" levels of pathology, whereas the conventional means and outlier methods can only provide a dichotomous "normal" or "abnormal" decision. Therefore, Bayesian muscle characterization can be directly used to support clinical decisions related to initial diagnosis as well as treatment and management over time. Decisions are based on facts and not impressions giving electromyography a more reliable role in the diagnosis, management, and treatment of neuromuscular disorders.
  
  
  CONCLUSIONS
  Bayesian muscle characterization can help make electrophysiological examinations more accurate and objective.
authors.affiliation: Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, Waterloo, Ont., Canada N2L 3G1. ljpino@uwaterloo.ca
authors.forename: L J
authors.initials: LJ
authors.lastname: Pino
authors.forename: D W
authors.initials: DW
authors.lastname: Stashuk
authors.forename: S
authors.initials: S
authors.lastname: Podnar