title: Nocardia brain abscess: severe CNS infection that needs aggressive management; case report.
abstract: Nocardia brain abscess is a rare central nervous system (CNS) infection that carries a high mortality rate reaching 34% which is considered the highest amongst brain abscesses caused by microorganisms. All available literature is in the form of retrospective studies and small case series. In this case report the authors present a patient whose course of disease was stormy and required multiple neurosurgical procedures. The clinical outcome, long-term follow up and a review of the literature is discussed.
authors.affiliation: Division of Neurosurgery, King Khalid University Hospital, Riyadh, Saudi Arabia.
authors.forename: Amr
authors.initials: A
authors.lastname: Zakaria
authors.forename: Sherif
authors.initials: S
authors.lastname: Elwatidy
authors.forename: Essam
authors.initials: E
authors.lastname: Elgamal
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D001922:Brain Abscess / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D003399:Craniotomy; D018450:Disease Progression; D004359:Drug Therapy, Combination; D019693:Hepatitis, Autoimmune / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D019586:Intracranial Hypertension / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D009617:Nocardia Infections / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents