[Influence of heart rate's circadian rhythm in postoperation of intracerebral hemorrhage with different surgery].
OBJECTIVE
To study the influence of different surgery on heart rate's circadian rhythm in postoperation of intracerebral hemorrhage.


METHODS
One hundren cases of hypertensive intracerebral hemorrhage at basal ganglia had been collected. According to methods of operation, cases were divided into two groups. Forty-three cases and 57 cases were treated respectively by standard craniotomy (Craniotomy group) and microinvasion of puncturation (Microinvasion group) to remove hematoma. Value of heart rate (HR) was recorded by monitor every 1 hour for 9 days. Circadian rhythm of every day was analyzed by single cosinor and population mean-cosinor.


RESULTS
Circadian rhythm of postoperative HR appeared (P < 0.001) in microinvasion group after operation. Circadian rhythm of postoperative HR had not been appearing (P < 0.001) in craniotomy group until to the 8th day. All amplitudes in microinvasion group are higher than that in craniotomy group. Both of amplitudes in two groups begin to be low during 4-7 d after operation and recover the level till the 8th day.


CONCLUSIONS
Influence of circadian rhythm in craniotomy was more severe than microinvasion puncturation. There would be a intimate relationship between encephaledema and recovery of circadian rhythm after neurosurgery.
Guan
Jun-wen
JW
Department of Biomedical Engineering, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Liu
Yan-yu
YY
Zhao
Kang-dong
KD
Liu
Yan-you
YY
Wang
Yu-hui
YH
Jiang
Zhou
Z
Wang
Zheng-rong
ZR
D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000503:physiopathology* / Q000601:surgery*; D002940:Circadian Rhythm; D003399:Craniotomy / Q000379:methods; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D011184:Postoperative Period; D013997:Time Factors