title: Hypogonadotropic hypogonadism: a consequence of Chiari-I malformation.
abstract: Chronic hydrocephalus, most commonly the result of aqueduct stenosis, is associated with both primary and secondary amenorrhea. Only six cases of secondary amenorrhea have been reported to date. We describe a women with cystic fibrosis who presented with secondary amenorrhea as a consequence of Chiari-I malformation and resultant hydrocephalus. The biochemical picture was characterized by hypogonadotropic hypogonadism. Resolution of the amenorrhea was observed to occur following 3rd ventriculostomy.
authors.affiliation: Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, D Floor, Brotherton Wing, Leeds General Infirmary, Great George Street, Leeds, UK.
authors.forename: Sampath Satish
authors.initials: SS
authors.lastname: Kumar
authors.forename: Paul
authors.initials: P
authors.lastname: Chumas
authors.forename: Daniel
authors.initials: D
authors.lastname: Peckham
authors.forename: Ashley
authors.initials: A
authors.lastname: Guthrie
authors.forename: Robert D
authors.initials: RD
authors.lastname: Murray
mesh_terms: D000568:Amenorrhea / Q000473:pathology / Q000601:surgery; D001139:Arnold-Chiari Malformation / Q000150:complications*; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014696:Ventriculostomy; D055815:Young Adult
references.citation: Eur J Endocrinol. 1998 Feb;138(2):170-5
references.pmid: 9506861
references.citation: Pediatr Dev Pathol. 2003 Jan-Feb;6(1):88-93
references.pmid: 12415481
references.citation: Pediatr Pulmonol. 2000 Dec;30(6):490-2
references.pmid: 11109062
references.citation: Eur J Pediatr. 1997 Aug;156(8):597-601
references.pmid: 9266188
references.citation: J Neurosurg. 1996 Dec;85(6):1148-52
references.pmid: 8929509
references.citation: Childs Nerv Syst. 1995 Mar;11(3):180-5
references.pmid: 7773981
references.citation: Fertil Steril. 2001 Aug;76(2):390-3
references.pmid: 11476794
references.citation: J Korean Med Sci. 2001 Aug;16(4):532-6
references.pmid: 11511805