[Correlation between syndrome factor combination and cardiac function as well as blood-lipid in coronary heart disease].
OBJECTIVE
To discuss the distribution laws of traditional Chinese medicine (TCM) syndrome factor and their combination in coronary heart disease (CHD), and to study the correlation between the TCM syndrome factor combination and cardiac function as well as blood-lipid.


METHODS
The parameters of the cardiac function of 300 patients with a final diagnosis of CHD by coronary angiography were measured by echocardiography, and the levels of blood lipids in the CHD patients were detected. An analysis of the correlation was done between the TCM syndrome factor combination and cardiac function as well as blood-lipid in CHD.


RESULTS
The TCM syndrome factor combinations of CHD were blood stasis due to qi deficiency, qi and yin deficiency, intermingled phlegm and blood stasis, and yang deficiency and blood stasis. The ejection fraction of CHD patients with yang deficiency and blood stasis was markedly decreased. The levels of triglyceride and low-density lipoprotein cholesterol in CHD patients with intermingled phlegm and blood stasis were markedly increased, and the level of triglyceride in CHD patients with qi and yin deficiency was markedly increased too.


CONCLUSIONS
The treatment of CHD should aim directly at the symptoms and causes. It is also proved that some compound traditional Chinese herbal medicines for supplementing qi and activating blood circulation, nourishing yin and resolving phlegm, and activating yang should be used in treatment of CHD. In cases of CHD with low cardiac function, particular emphasis should be laid on activating yang and blood circulation, while in cases of CHD with blood-lipid disturbance, particular emphasis should be laid on resolving phlegm and activating blood circulation, replenishing qi and nourishing yin.
Wang
Jie
J
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
He
Qing-Yong
QY
Shi
Zhan
Z
Xing
Yan-Wei
YW
Li
Ji
J
Fang
Yu-Tao
YT
Tang
Yan-Li
YL
D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D013577:Syndrome
D004365:Drugs, Chinese Herbal; D008055:Lipids