[The effects of normal vaginal delivery on oxygen transport to the fetus].
OBJECTIVE
To evaluate the effects of normal vaginal delivery (NVD) on oxygen transport to the fetus. Study group and methods: Fifty newborn infants born by NVD and as a control group 50 infants born by elective Cesarean section (ECS) were studied. Factors reflecting oxygen transport to the fetus were measured in venous and arterial cord blood: pH, partial pressure of oxygen (pO2) and carbon dioxide (pCO2), oxygen saturation (SO2), blood oxygen content, base deficit, and lactic acid concentrations, erythropoietin concentrations, number of nucleated red blood cells and haemoglobin concentrations.


RESULTS
There was no significant difference in venous blood oxygen content between the two groups of infants. However, arterial blood oxygen content was significanlty lower in the infants born by ECS than in those born by NVD (p<0.001). Infants born by NVD had significantly lower pH (p<0.001), greater base deficit (p<0.001), higher lactic acid (p<0.001) and erythropoietin concentrations (p=0.01), more nucleated red blood cells (p=0.004), and higher hemoglobin concentrations (p=0.002) in venous blood than in the infants born by ECS. pH was lower (p<0.001) and lactic aicid concentrations were higher (p<0.001) in arterial blood than venous blood in both groups of infants.


CONCLUSIONS
(1) NVD causes reduction in oxygen transport to the fetus, resulting in acidosis and stimulation of blood forming tissues. (2) ECS is associated with more reduction in umbilical arterial cord blood oxygen content than NVD. (3) When evaluating acidosis in newborns after delivery it is more reliable to measure pH and lactic acid concentrations in arterial rather than venous cord blood.
Thorkelsson
Thordur
T
Bjarnason
Anton Orn
AO
Hardardottir
Hildur
H
Thorsteinsson
Adalbjorn
A
Haraldsson
Asgeir
A
Dagbjartsson
Atli
A
D000328:Adult; D002245:Carbon Dioxide / Q000097:blood; D016022:Case-Control Studies; D002585:Cesarean Section; D036861:Delivery, Obstetric; D017558:Elective Surgical Procedures; D004900:Erythroblasts; D004906:Erythrocyte Count; D004921:Erythropoietin / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D019344:Lactic Acid / Q000097:blood; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D011247:Pregnancy
D006454:Hemoglobins; D004921:Erythropoietin; D002245:Carbon Dioxide; D019344:Lactic Acid; D010100:Oxygen