title: [Diagnostic accuracy and time-course change of cervical intraepithelial neoplasia].
abstract: We investigated the results of cervical cytology, pathology of colposcopic biopsy and surgical specimen among 765 women suspected to have cervical intraepithelial neoplasia (CIN). Significantly more patients with cervical cytology class III b than class III a were diagnosed in CIN grade 3 on colposcopic biopsy. The concordance rate of colposcopic biopsy and surgical specimen was 79.8%, but we preoperatively diagnosed CIN grade 3 or more at 96.1% with colposcopic biopsy. In time course observation, CIN regressed in 26.3% of all patients, progressed in 19.3% and did not change in 54.4%. Many patients of CIN grade 2 progressed to grade 3 in two years. Significantly more patients of CIN grade 1 or 2 with cervical cytology class III b progressed than with class III a (p<0.05).
authors.affiliation: Dept. of Obstetrics and Gynecology, Japanese Red Cross Nagoya First Hospital.
authors.forename: Ken
authors.initials: K
authors.lastname: Miyazaki
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Hiromura
authors.forename: Kojiro
authors.initials: K
authors.lastname: Minami
authors.forename: Junko
authors.initials: J
authors.lastname: Saito
authors.forename: Kimio
authors.initials: K
authors.lastname: Mizuno
authors.forename: Masahiko
authors.initials: M
authors.lastname: Fujino
authors.forename: Masafumi
authors.initials: M
authors.lastname: Itou
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D001706:Biopsy; D003127:Colposcopy; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D013997:Time Factors; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery