title: Reduced-representation methylation mapping.
abstract: The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.
authors.affiliation: Roche NimbleGen Inc, Research and Development, 500 S. Rosa Rd, Madison, WI 53719, USA. jeffrey.jeddeloh@roche.com
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Jeddeloh
authors.forename: John M
authors.initials: JM
authors.lastname: Greally
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Rando
mesh_terms: D000818:Animals; D003596:Cytosine / Q000378:metabolism; D019175:DNA Methylation / Q000502:physiology; D044127:Epigenesis, Genetic; D023281:Genomics / Q000379:methods; D051379:Mice; D017422:Sequence Analysis, DNA / Q000379:methods*
chemical_list: D003596:Cytosine
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