Influence of temperature and rainfall on the evolution of cholera epidemics in Lusaka, Zambia, 2003-2006: analysis of a time series.
In this study, we aimed to describe the evolution of three cholera epidemics that occurred in Lusaka, Zambia, between 2003 and 2006 and to analyse the association between the increase in number of cases and climatic factors. A Poisson autoregressive model controlling for seasonality and trend was built to estimate the association between the increase in the weekly number of cases and weekly means of daily maximum temperature and rainfall. All epidemics showed a seasonal trend coinciding with the rainy season (November to March). A 1 degrees C rise in temperature 6 weeks before the onset of the outbreak explained 5.2% [relative risk (RR) 1.05, 95% CI 1.04-1.06] of the increase in the number of cholera cases (2003-2006). In addition, a 50 mm increase in rainfall 3 weeks before explained an increase of 2.5% (RR 1.02, 95% CI 1.01-1.04). The attributable risks were 4.9% for temperature and 2.4% for rainfall. If 6 weeks prior to the beginning of the rainy season an increase in temperature is observed followed by an increase in rainfall 3 weeks later, both exceeding expected levels, an increase in the number of cases of cholera within the following 3 weeks could be expected. Our explicative model could contribute to developing a warning signal to reduce the impact of a presumed cholera epidemic.
Luque Fernández
Miguel Angel
MA
National Centre of Epidemiology (CNE), Programa de Epidemiología Aplicada de Campo, Instituto de Salud Carlos III, C/Sinesio Delgado 6, Pabellón 12, 28029 Madrid, Spain. fmiguelangel@isciii.es
Bauernfeind
Ariane
A
Jiménez
Julio Díaz
JD
Gil
Cristina Linares
CL
El Omeiri
Nathalie
N
Guibert
Dionisio Herrera
DH
D002771:Cholera / Q000453:epidemiology*; D002980:Climate; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D006801:Humans; D015233:Models, Statistical; D011159:Population Surveillance; D011891:Rain; D012307:Risk Factors; D012621:Seasons; D015024:Zambia / Q000453:epidemiology