Intramuscular administration of AAV1-lipoprotein lipase S447X lowers triglycerides in lipoprotein lipase-deficient patients.
Stroes
Erik S
ES
Vascular Medicine, AMC, the Netherlands.
Nierman
Melchior C
MC
Meulenberg
Janneke J
JJ
Franssen
Remco
R
Twisk
Jaap
J
Henny
C Pieter
CP
Maas
Mario M
MM
Zwinderman
Aeilko H
AH
Ross
Colin
C
Aronica
Eleonora
E
High
Katherine A
KA
Levi
Marcel M
MM
Hayden
Michael R
MR
Kastelein
John J
JJ
Kuivenhoven
Jan Albert
JA
D000229:Dependovirus / Q000235:genetics / Q000276:immunology; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D006801:Humans; D008072:Hyperlipoproteinemia Type I / Q000097:blood / Q000201:enzymology / Q000235:genetics / Q000628:therapy*; D007273:Injections, Intramuscular; D008071:Lipoprotein Lipase / Q000235:genetics*; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D008071:Lipoprotein Lipase