title: Risk factors for uncontrolled intraocular pressure after phacoviscocanalostomy.
abstract: OBJECTIVE
  To determine factors affecting the outcome of phacoviscocanalostomy in patients with cataract and primary open-angle glaucoma.
  
  
  METHODS
  Factors for controlling intraocular pressure (IOP) were investigated in 180 patients using Cox multivariate proportional hazards survival regression.
  
  
  RESULTS
  The mean preoperative IOP of 20.2+/-3.8 mm Hg decreased significantly (P<0.0001) to 15.3+/-2.6 mm Hg for 5 years postoperatively. The success probabilities defined as an IOP of 17 mm Hg or less or a 20% or greater reduction were 47.2% with or without medications and 31.4% without medications at 5 years. Preoperative IOP level [P=0.0013; odds ratio (OR), 1.14] and age (P=0.037; OR, 0.97) were risk factors in the success probability with or without medications. In the analysis without medications, the preoperative IOP (P<0.001; OR, 1.12), the preoperative number of antiglaucoma medications (P=0.033; OR, 1.27), age (P=0.003; OR, 0.96), and IOP spikes (P=0.028; OR, 1.22) were associated with failure. Sex, peeling of juxtacanalicular tissue, ruptured Descemet membrane, fibrin formation, and hyphema did not affect surgical outcomes.
  
  
  CONCLUSIONS
  High preoperative IOP, the number of preoperative medications, postoperative IOP spikes (>30 mm Hg) increased the risk of failed IOP control after phacoviscocanalostomy. Increasing patient age decreased the risk of failure.
authors.affiliation: Sensho-kai Eye Institute daggerthe Department of Ophthalmology, Takeda Hospital in Kyoto, Japan. mpark@belle.shiga-med.ac.jp
authors.forename: Masami
authors.initials: M
authors.lastname: Park
authors.forename: Ken
authors.initials: K
authors.lastname: Hayashi
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Takahashi
authors.forename: Takuhei
authors.initials: T
authors.lastname: Shoji
authors.forename: Etsuo
authors.initials: E
authors.lastname: Chihara
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications / Q000628:therapy*; D005260:Female; D018463:Filtering Surgery / Q000379:methods*; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D013524:Surgical Flaps; D014065:Tonometry, Ocular