title: Imaging serpiginous choroidopathy with spectral domain optical coherence tomography.
abstract: The use of spectral domain optical coherence tomography (SD-OCT) in the study of chronic serpiginous choroiditis was evaluated. Two patients with chronic serpiginous choroiditis were imaged using two prototype SD-OCT systems (6-microm axial resolution). Raster scans covering 6 x 6 X 2-mm regions of the retina were obtained, enabling the study of different retinal cross-sectional images. Thickness maps were obtained after segmentation of retinal layers, which could be compared with those on follow-up. SD-OCT allowed the visualization of the cross-sectional retinal architecture at different horizontal positions. Superimposition of SD-OCT generated reconstructed fundus images with fundus photographs provided accurate images registration. Segmentation of retinal layers provided thickness maps and higher-density improved visualization of photoreceptor layer, cysts, and atrophy, which was useful in following change in disease activity over time. The researchers concluded that SD-OCT is a useful tool to study disease morphology and follow-up of chronic serpiginous choroiditis.
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors.forename: Omar S
authors.initials: OS
authors.lastname: Punjabi
authors.forename: Ryan
authors.initials: R
authors.lastname: Rich
authors.forename: Janet L
authors.initials: JL
authors.lastname: Davis
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gregori
authors.forename: Harry W
authors.initials: HW
authors.lastname: Flynn
authors.forename: Brandon J
authors.initials: BJ
authors.lastname: Lujan
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenfeld
authors.forename: Carmen A
authors.initials: CA
authors.lastname: Puliafito
mesh_terms: D000369:Aged, 80 and over; D002196:Capillaries / Q000473:pathology; D002825:Chorioretinitis / Q000473:pathology*; D002829:Choroid / Q000098:blood supply / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*