A scoring system for management of acute pharyngo-tonsillitis in adults.
OBJECTIVE
The aim of this study was to develop and evaluate a scoring system for the management of acute pharyngo-tonsillitis.


METHODS
We conducted a prospective study between May 2004 and June 2005. Patients with acute pharyngo-tonsillitis were evaluated for causative pathogens and were assessed clinical symptoms and pharyngo-tonsillar finding by a clinical scoring system.


RESULTS
A total 214 adult patients were enrolled in this study. Streptococcus pyogenes were identified at 13.6%. Thirty-one viruses were also identified by PCR. They were adenovirus (4.8%), influenza virus (1.0%), RS virus (6.3%), and human metapneumovirus (2.9%). Numbers of total white blood cells and levels of C-reactive protein showed a significant positive correlation with clinical scores (p<0.001) and were also higher in cases with S. pyogenes. The clinical scores rapidly improved after the antimicrobial treatments in moderate cases and severe cases.


CONCLUSIONS
The current study strongly suggested that the clinical scoring system reflected disease severity well and would be very useful for evaluating clinical course and decision making for the antimicrobial treatment of acute pharyngo-tonisllitis.
Suzumoto
Masaki
M
Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University, 811-1 Wakayama-shi, Wakayama 641-8510, Japan.
Hotomi
Muneki
M
Billal
Dewan S
DS
Fujihara
Keiji
K
Harabuchi
Yasuaki
Y
Yamanaka
Noboru
N
D000208:Acute Disease; D000234:Adenoids; D000257:Adenoviridae Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D006801:Humans; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011446:Prospective Studies; D012107:Research Design / Q000706:statistics & numerical data*; D013290:Streptococcal Infections / Q000150:complications / Q000188:drug therapy; D013297:Streptococcus pyogenes / Q000302:isolation & purification; D014069:Tonsillitis / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D014777:Virus Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D055815:Young Adult
D000890:Anti-Infective Agents; D002097:C-Reactive Protein
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