Iloprost treatment for refractory Raynaud's phenomenon in two infants.
Raynaud's phenomenon (RP) is rare in young children. We describe two infants with severe RP, manifesting as fingertip necrosis, who were resistant to conventional vasodilators and were treated successfully with iloprost, a prostacyclin analogue. The application of iloprost is safe and should be considered in children with threatening ischemic digits.
Shouval
D S
DS
Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. dror_sho@netvision.net.il
Mukamel
M
M
Zulian
F
F
Amir
J
J
Harel
L
L
D005260:Female; D005385:Fingers / Q000098:blood supply / Q000473:pathology; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D009336:Necrosis; D011928:Raynaud Disease / Q000188:drug therapy* / Q000473:pathology; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D016285:Iloprost