[Expression of CD34 and CD117 in juxtaglomerular cell tumor of kidney].
Juxtaglomerular cell tumor (JGCT) is an uncommon tumor of the kidney, typically found in young adults. Patients with this tumor suffer from hypertension, hyperaldosteronism and hypokalaemia. Expression of renin and intracytoplasmatic rhomboid crystals or granules in electron microscopic picture are diagnostic features of this tumor. CD34 and CD117 immunoreactivity have recently been reported as helpful markers of JGCT.
Pavlovský
Z
Z
Ustav patologie FN Brno a LF MU. zpavlovsky@fnbrno.cz
Habanec
B
B
Feit
J
J
Kren
L
L
Cech
S
S
Charvátová
M
M
D000293:Adolescent; D018952:Antigens, CD34 / Q000032:analysis*; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology; D007606:Juxtaglomerular Apparatus; D007680:Kidney Neoplasms / Q000737:chemistry / Q000150:complications / Q000473:pathology*; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis*
D018952:Antigens, CD34; D019009:Proto-Oncogene Proteins c-kit