Pregnancy- and lactation-associated osteoporosis with severe vertebral deformities: can strontium ranelate be a new alternative for the treatment?
BACKGROUND
Pregnancy- and lactation-associated osteoporosis is an uncommon condition that may be a consequence of preexisting low bone density, loss of bone mineral content during pregnancy, and increased bone turnover.


OBJECTIVE
To present a case of severe osteoporosis associated with pregnancy and lactation and its treatment protocol.


METHODS
A tertiary care hospital.


METHODS
A young female after twin pregnancy presenting with severe osteoporosis.


METHODS
The diagnosis was done on the basis of bone mineral density (BMD) measurement. The patient was treated with first alendronate and then strontium ranelate. She was considered as a candidate for kyphoplasty.


RESULTS
A dramatic increase in the BMD and palliation of back pain were observed.


CONCLUSIONS
Strontium ranelate may be a new alternative in the treatment of pregnancy- and lactation-associated osteoporosis.
Tanriover
Mine Durusu
MD
Department of Medicine, Section of General Medicine, Faculty of Medicine, Hacettepe University, Sihhiye, Ankara, Turkey. mdurusu@hacettepe.edu.tr
Oz
S Gul
SG
Sozen
Tumay
T
Kilicarslan
Alpaslan
A
Guven
Gulay Sain
GS
D001416:Back Pain / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007774:Lactation; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D009942:Organometallic Compounds / Q000008:administration & dosage*; D010024:Osteoporosis / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D011085:Polycystic Ovary Syndrome / Q000150:complications; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications; D011859:Radiography; D012720:Severity of Illness Index; D013876:Thiophenes / Q000008:administration & dosage*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D055815:Young Adult
D050071:Bone Density Conservation Agents; D009942:Organometallic Compounds; D013876:Thiophenes; C081587:strontium ranelate