title: Recovery of a functional class 2 integron from an Escherichia coli strain mediating a urinary tract infection.
abstract: A class 2 integron was found in an Escherichia coli isolate mediating a urinary tract infection. Unlike other class 2 integrons from pathogens, the encoded IntI2 protein was functional. The integron possessed a dfrA14 cassette, and a second novel cassette in which a lipoprotein signal peptidase gene is predicted.
authors.affiliation: Facultad de Ciencias, Cátedra de Microbiología, Instituto de Química Biológica, Montevideo, Uruguay.
authors.forename: Carolina
authors.initials: C
authors.lastname: Márquez
authors.forename: Maurizio
authors.initials: M
authors.lastname: Labbate
authors.forename: Ana J
authors.initials: AJ
authors.lastname: Ingold
authors.forename: Piklu
authors.initials: P
authors.lastname: Roy Chowdhury
authors.forename: Maria S
authors.initials: MS
authors.lastname: Ramírez
authors.forename: Daniela
authors.initials: D
authors.lastname: Centrón
authors.forename: Graciela
authors.initials: G
authors.lastname: Borthagaray
authors.forename: H W
authors.initials: HW
authors.lastname: Stokes
mesh_terms: D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D005798:Genes, Bacterial; D006801:Humans; D019426:Integrases / Q000235:genetics*; D032023:Integrons; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D011995:Recombination, Genetic; D014552:Urinary Tract Infections / Q000382:microbiology*
chemical_list: D029968:Escherichia coli Proteins; C451959:InTI2 protein, E coli; D019426:Integrases
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