An inverse age resistance of chicken kidneys to infectious bronchitis virus.
Ten-fold serial dilutions of the H52 vaccine strain of infectious bronchitis virus were inoculated intravenously into 3-week-old and 10-week-old chickens. The severity of the histological lesions in the kidney was graded and described. The younger birds were much more resistant to the nephritogenic effects of the virus. Although very small doses of virus caused nephritis, no marked dose-related response was demonstrated in either age group.
Macdonald
J W
JW
Ministry of Agriculture, Fisheries and Food, Veterinary Laboratory, Lasswade Midlothian, Scotland.
Randall
C J
CJ
McMartin
D A
DA