Photoactivity of kynurenine-derived UV filters.
Quantum yields of photodecomposition and triplet state formation under aerobic and anaerobic conditions are determined for kynurenine (KN), 3-hydroxykynurenine (3OHKN), xanthurenic acid (XAN), and kynurenine adducts of glutathione (GSH-KN), cysteine (Cys-KN), histidine (His-KN), and lysine (Lys-KN) in aqueous solutions. The highest yields of anaerobic photodecomposition were obtained for GSH-KN and His-KN adducts, which correlates with the highest triplet yields for these compounds. In aerobic conditions, the photodecomposition yields for all compounds under study increase; the highest decomposition rates were observed for His-KN and 3OHKN. The fast decomposition of the latter is attributed to the dark autoxidation of the starting compound.
Sherin
P S
PS
International Tomography Center, Institutskaya 3a, 630090 Novosibirsk, Russia.
Tsentalovich
Yu P
YP
Snytnikova
O A
OA
Sagdeev
R Z
RZ
D000693:Anaerobiosis; D003545:Cysteine / Q000737:chemistry / Q000528:radiation effects; D005978:Glutathione / Q000737:chemistry / Q000528:radiation effects; D006639:Histidine / Q000737:chemistry / Q000528:radiation effects; D007737:Kynurenine / Q000737:chemistry / Q000528:radiation effects*; D010782:Photolysis; D011789:Quantum Theory; D012542:Scattering, Radiation; D013997:Time Factors; D014466:Ultraviolet Rays
D007737:Kynurenine; D006639:Histidine; D005978:Glutathione; D003545:Cysteine