[Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV].
Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.
Takada
Kazuto
K
Division of Respiratory and Allergy Medicine, Komaki Municipal Hospital.
Matsumoto
Shuuichi
S
Hiramatsu
Tetsuo
T
Kojima
Eiji
E
Watanabe
Hiroaki
H
Sizu
Masato
M
Okachi
Shoutarou
S
Ninomiya
Kiyoko
K
D000368:Aged; D002908:Chronic Disease; D005260:Female; D006699:Home Care Services; D006801:Humans; D006934:Hypercalcemia / Q000628:therapy; D008297:Male; D011175:Positive-Pressure Respiration; D012131:Respiratory Insufficiency / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate