title: Proposal for a fourth aquabirnavirus serogroup.
abstract: Four putative aquabirnaviruses, based on morphology, nucleic acid type and partial RNA-dependent RNA polymerase gene (VP1) sequence, isolated from three tropical freshwater fish species were not neutralised by antisera against type members of the Aquabirnavirus genus serogroups A, B or C. Antisera produced against two of the isolates neutralised the homologous and heterologous isolates, but not any type member of Aquabirnavirus serogroups A, B or C. The serological comparisons suggest that the four isolates should be regarded as members of a fourth Aquabirnavirus serogroup, D.
authors.affiliation: CEFAS Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset, UK. peter.dixon@cefas.co.uk
authors.forename: P F
authors.initials: PF
authors.lastname: Dixon
authors.forename: G-H
authors.initials: GH
authors.lastname: Ngoh
authors.forename: D M
authors.initials: DM
authors.lastname: Stone
authors.forename: S F
authors.initials: SF
authors.lastname: Chang
authors.forename: K
authors.initials: K
authors.lastname: Way
authors.forename: S L F
authors.initials: SL
authors.lastname: Kueh
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D019201:Aquabirnavirus / Q000145:classification* / Q000276:immunology* / Q000302:isolation & purification / Q000648:ultrastructure; D005399:Fishes / Q000821:virology; D005838:Genotype; D008969:Molecular Sequence Data; D009500:Neutralization Tests; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D012703:Serotyping; D014764:Viral Proteins / Q000235:genetics
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral; D014764:Viral Proteins; D012324:RNA-Dependent RNA Polymerase