title: [Radical cystectomy as a muscle-invasive bladder cancer treatment in elderly patients].
abstract: BACKGROUND
  Radical cystectomy in elderly is a controversial issue that increases importance overtime because average life span is growing.
  
  
  OBJECTIVE
  The purpose of our work was to analize the differences about perioperative and later outcomes between ages of patients with muscle-invasive bladder neoplasm treated with radical cystectomy.
  
  
  METHODS
  We retrospectively reviewed the records of patients who underwent radical cystectomy for muscle-invasive bladder cancer. Two age groups were compared: < 70-years-old at time of cystectomy (n = 55) and > or = 70 years (n = 57).
  
  
  RESULTS
  There was no difference between both age groups about: time of surgery, intraoperative complications (< 70 = 21,8%, > or = 70 = 31,6%), postoperative mortality (< 70 = 3,6%, > or = 70 = 8,8%), minor (< 70 = 18,2%, > or = 70 = 26,3%) and major medical postoperative complications (< 70 = 7,3%, > or = 70 = 8,8%), late outcomes as cancer-specific morby-mortality and actuarial overall survival stratified by patient age. The rate of major postoperative complications (< 70 = 23,6%, > or = 70 = 43,9%) as well as the mean length of hospital stay (< 70 = 10,2, > or = 70 = 15,2 days) differed significantly between the two age groups. Age and cardiovascular risk factors were independient predictive factors of mayor postoperative complications.
  
  
  CONCLUSIONS
  Radical cystectomy could be performed in carefully selected elderly patients.
authors.affiliation: Servicio de Urología del Hospital Clínico Universitario de Valencia, Valencia. joseantoniomarch@hotmail.com
authors.forename: J A
authors.initials: JA
authors.lastname: March Villalba
authors.forename: J M
authors.initials: JM
authors.lastname: Martínez Jabaloyas
authors.forename: F
authors.initials: F
authors.lastname: Pastor Hernández
authors.forename: F J
authors.initials: FJ
authors.lastname: Günthner Stefan
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez Navarro
authors.forename: P
authors.initials: P
authors.lastname: Chuan Nuez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015653:Cystectomy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*