A one step synthetic approach to L-pyrimidine nucleosides using natural phosphate coated with potassium iodide as catalyst.
The one-step synthesis of several alpha-L-arabino and beta-L- xylonucleosides was performed in good yields under mild conditions by N-glycosylation of 1-O-acetyl-L-arabino and -xylofuranose using Vorbruggen type reaction conditions with or without Microwave irradiation.
Lazrek
Hassan B
HB
Unité de Chimie Biomoléculaire et Médicinale, Faculté des Sciences Semlalia, Université cadi-Ayyad, 40000 Marrakesh, Morocco.
Baddi
Laila
L
Ouzebla
Driss
D
Smietana
Michael
M
Vasseur
Jean-Jacques
JJ
D001089:Arabinose / Q000737:chemistry; D002384:Catalysis; D006031:Glycosylation; D008872:Microwaves; D010710:Phosphates / Q000737:chemistry*; D011193:Potassium Iodide / Q000737:chemistry*; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D014994:Xylose / Q000737:chemistry
D010710:Phosphates; D011741:Pyrimidine Nucleosides; D011193:Potassium Iodide; D014994:Xylose; D001089:Arabinose