Offline LC-GC x GC in combination with rapid-scanning quadrupole mass spectrometry.
The present research is focused on the offline combination of normal-phase LC to double-oven GC x GC-quadrupole MS. Initially, a diesel sample was subjected to automated LC x GC in order to define the elution windows of four fractions, viz., saturated hydrocarbons, monocyclic aromatics, dicyclic aromatics, tri- + tetracyclic aromatics; each fraction was collected exploiting the LC system in a further analysis and subjected to large-volume-injection-GC x GC analysis using an apolar-polar column combination. The GC x GC operational conditions were tuned in relation to the specific separation requirements of each heart-cut. The main benefits of what can be defined as offline LC-GC x GC were: (i) the high first-dimension LC selectivity; (ii) the injection of high sample amounts in the GC x GC system, enabling the detection and quantification of a series of low-amount diesel constituents; (iii) improved GC x GC operational conditions for each heart-cut with respect to direct GC x GC.
Sciarrone
Danilo
D
Dipartimento Farmaco-chimico, Facoltà di Farmacia, Università di Messina, Messina, Italy.
Tranchida
Peter Quinto
PQ
Costa
Rosaria
R
Donato
Paola
P
Ragonese
Carla
C
Dugo
Paola
P
Dugo
Giovanni
G
Mondello
Luigi
L
D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods*; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods*; D005742:Gasoline / Q000032:analysis; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*
D005742:Gasoline