Asymmetric hydrogenation of cyclic imines with an ionic Cp*Rh(III) catalyst.
When associated with a noncoordinating bulky counteranion, a cationic Cp*Rh(III)-diamine catalyst displayed excellent enantioselectivities in asymmetric hydrogenation of cyclic imines, affording bioactive tetrahydroisoquinolines and tetrahydro-beta-carbolines frequently with 99% ee's.
Li
Chaoqun
C
Department of Chemistry, Liverpool Centre for Materials and Catalysis, University of Liverpool, Liverpool L69 7ZD, UK.
Xiao
Jianliang
J
D000588:Amines / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D015394:Molecular Structure; D017975:Ruthenium Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000588:Amines; D007097:Imines; D007477:Ions; D017975:Ruthenium Compounds