Diagnosis of Helicobacter pylori.
The different invasive and noninvasive diagnostic tests for Helicobacter pylori have been applied mainly in emerging countries. Molecular methods have been developed, especially a test for detection of H. pylori and its clarithromycin resistance directly from stools. The long-term effects of eradication on histologic lesions have been studied in a meta-analysis and the prognostic value of post-treatment in gastric mucosa-associated lymphoid tissue lymphoma has been assessed. An operating link for gastritis assessment (the OLGA staging) has also been published. Attempts to simplify the urea breath test protocol have been made, and new stool antigen tests have been proposed and compared to those previously available.
Granstrom
Marta
M
Clinical Microbiology, Karolinska Hospital, SE171 76 Stockholm, Sweden.
Lehours
Philippe
P
Bengtsson
Carina
C
Mégraud
Francis
F
D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001944:Breath Tests; D019937:Diagnostic Techniques and Procedures / Q000191:economics; D005243:Feces / Q000737:chemistry / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D006801:Humans; D016133:Polymerase Chain Reaction; D014510:Urease / Q000235:genetics / Q000378:metabolism
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D014510:Urease