Your diagnosis? A 12-year-old girl with latent tuberculosis presenting with nausea, vomiting and increasing frontal headache.
A 12-year-old girl with latent Mycobacterium tuberculosis infection and currently receiving prophylaxis with isoniazid presented with nausea, vomiting and increasing frontal headache. Toxicity to the anti-tuberculosis drug was suspected, but her symptoms persisted after isoniazid withdrawal. A computed tomography (CT) scan showed a brain mass to be present.
De Gaudio
Marina
M
Department of Paediatrics, University of Florence, Anna Meyer Children's Hospital, via Luca Giordano 13, 50132 Florence, Italy.
Chiappini
Elena
E
Catania
Piera
P
Mussa
Federico
F
Galli
Luisa
L
de Martino
Maurizio
M
D000995:Antitubercular Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage* / Q000009:adverse effects; D008527:Medulloblastoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009325:Nausea / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000517:prevention & control; D014839:Vomiting / Q000209:etiology*
D000995:Antitubercular Agents; D007538:Isoniazid
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