title: Synthesis of carbocyclic 2-substituted adenine nucleoside and related analogs.
abstract: 2-Iodonoraristeromycin, 2-iodoaristeromycin and related analogs were synthesized to investigate their inhibitory activities against human and Plasmodium falciparum S-adenosyl-L-homocysteine hydrolases.
authors.affiliation: Department of Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan.
authors.forename: Fazila
authors.initials: F
authors.lastname: Zulfiqar
authors.forename: Hiroharu
authors.initials: H
authors.lastname: Kojima
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakanishi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ando
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kitade
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D015394:Molecular Structure; D009699:N-Glycosyl Hydrolases / Q000037:antagonists & inhibitors*; D010963:Plasmodium falciparum / Q000201:enzymology*
chemical_list: C030034:aristeromycin; D009699:N-Glycosyl Hydrolases; D000241:Adenosine