title: Development of urine glucose meter based on micro-planer amperometric biosensor and its clinical application for self-monitoring of urine glucose.
abstract: The highly sensitive urine glucose meter based on amperometric glucose sensor was developed and commercialized. It shows remarkable performances of wide measurement range in 0-2000 mgdl(-1), rapid response time as 6s and robustness against influence by interferents like ascorbic acid or acetaminophen. Correlation between the developed urine glucose meter and commercialized clinical-use urine glucose analyzer showed excellent linear relationship. The monitoring of postmeal blood glucose levels by assess of urine glucose of actual subjects was performed with the developed urine glucose meter. The experimental results suggest the urine glucose level 120 min following the meal should be the appropriate index for diabetes or impaired glucose tolerance to control blood glucose level. The new portable meter was developed, and is expected for flexible use at places other than home or office.
authors.affiliation: TANITA Corporation, Itabashi-ku, Tokyo 174-8630, Japan.
authors.forename: Mariko
authors.initials: M
authors.lastname: Miyashita
authors.forename: Narushi
authors.initials: N
authors.lastname: Ito
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ikeda
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Murayama
authors.forename: Koji
authors.initials: K
authors.lastname: Oguma
authors.forename: Jun
authors.initials: J
authors.lastname: Kimura
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004563:Electrochemistry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis*; D008904:Miniaturization; D015203:Reproducibility of Results; D012648:Self Care / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D016482:Urinalysis / Q000295:instrumentation*
chemical_list: D005947:Glucose