title: Recombination in mitochondrial DNA of European mussels Mytilus.
abstract: Mitochondrial DNA was long believed to be purely clonal and free from recombination. Major phylogenetic studies still depend on such assumptions. The peculiar genetic system of marine mussels Mytilus in which two divergent mitochondrial genomes exist provides a unique opportunity to study mtDNA recombination. Previous reports showed the existence of a few haplotypes having very strong recombination signal in the control region of mtDNA. Those recombinant variants have been found in a Baltic Sea population of Mytilus trossulus as well as in Mytilus galloprovincialis from the Black Sea. In both cases the mosaic genomes switched their transmission route and have been inherited paternally. In the present study rearranged mtDNA genomes found in all three European Mytilus species are described. The structure of their control region is a result of intra- and intermolecular recombination between mitochondrial genomes. Together with the phylogenetic reconstruction and geographic distribution, this suggests that two interlineage recombination events have occurred in the control region of mtDNA of European mussels Mytilus. Contrary to earlier observations, some of the mosaic genomes do not show any gender bias, which has important implications regarding the transmission and evolution of blue mussel mitochondrial genomes.
authors.affiliation: Department of Genetics and Marine Biotechnology, Polish Academy of Sciences, Institute of Oceanology, Powstańców Warszawy 55, 81-712, Sopot, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Filipowicz
authors.forename: Artur
authors.initials: A
authors.lastname: Burzyński
authors.forename: Beata
authors.initials: B
authors.lastname: Smietanka
authors.forename: Roman
authors.initials: R
authors.lastname: Wenne
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D004272:DNA, Mitochondrial / Q000235:genetics*; D005060:Europe; D019143:Evolution, Molecular; D005260:Female; D016678:Genome / Q000235:genetics; D005843:Geography; D006239:Haplotypes; D008297:Male; D049878:Mytilus / Q000235:genetics*; D010802:Phylogeny; D011995:Recombination, Genetic / Q000235:genetics*; D017678:Sex Distribution
chemical_list: D004272:DNA, Mitochondrial
references.citation: AIDS Res Hum Retroviruses. 2005 Jan;21(1):98-102
references.pmid: 15665649
references.citation: Mol Biol Evol. 2005 Apr;22(4):952-67
references.pmid: 15647523
references.citation: Genetics. 1998 Jan;148(1):341-7
references.pmid: 9475744
references.citation: Mol Biol Evol. 2003 Mar;20(3):388-92
references.pmid: 12644559
references.citation: Mol Biol Evol. 2002 Feb;19(2):163-9
references.pmid: 11801744
references.citation: Brief Bioinform. 2004 Jun;5(2):150-63
references.pmid: 15260895
references.citation: Mol Biol Evol. 1996 Nov;13(9):1242-54
references.pmid: 8896377
references.citation: Mol Biol Evol. 2005 Apr;22(4):925-33
references.pmid: 15647518
references.citation: Evolution. 1996 Apr;50(2):952-957
references.pmid: 28568930
references.citation: Genetics. 2007 Feb;175(2):959-62
references.pmid: 17151240
references.citation: Mol Biol Evol. 1989 Sep;6(5):539-45
references.pmid: 2677600
references.citation: Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13757-62
references.pmid: 11717435
references.citation: Nat Genet. 2005 Aug;37(8):873-7
references.pmid: 16025113
references.citation: Mol Ecol. 2002 Apr;11(4):755-69
references.pmid: 11972762
references.citation: Nature. 1991 Jul 18;352(6332):255-7
references.pmid: 1857422
references.citation: Nature. 1989 Nov 23;342(6248):396-401
references.pmid: 2555716
references.citation: Mol Biol Evol. 2001 Oct;18(10):1929-39
references.pmid: 11557798
references.citation: Evolution. 2002 Nov;56(11):2252-61
references.pmid: 12487355
references.citation: Nucleic Acids Res. 1995 Dec 25;23(24):4992-9
references.pmid: 8559656
references.citation: J Mol Evol. 2005 Jun;60(6):764-73
references.pmid: 15931495
references.citation: Evolution. 2008 Apr;62(4):959-70
references.pmid: 18208565
references.citation: Nature. 1994 Apr 28;368(6474):817-8
references.pmid: 8159240
references.citation: Virology. 1999 Dec 20;265(2):218-25
references.pmid: 10600594
references.citation: Trends Genet. 2000 Jun;16(6):276-7
references.pmid: 10827456
references.citation: J Mol Evol. 2003;57 Suppl 1:S138-47
references.pmid: 15008410
references.citation: Genetics. 1997 Feb;145(2):383-94
references.pmid: 9071592
references.citation: J Mol Evol. 2005 Dec;61(6):717-32
references.pmid: 16315104
references.citation: Gene. 2007 Dec 30;406(1-2):79-90
references.pmid: 17611047
references.citation: Mol Biol Evol. 2001 Jul;18(7):1168-75
references.pmid: 11420358
references.citation: Mol Biol Evol. 2001 Jul;18(7):1330-42
references.pmid: 11420371
references.citation: J Mol Evol. 2005 Sep;61(3):381-9
references.pmid: 16082567
references.citation: Evolution. 1996 Dec;50(6):2276-2286
references.pmid: 28565656
references.citation: Comput Appl Biosci. 1989 Apr;5(2):151-3
references.pmid: 2720464
references.citation: Genetics. 2007 Jun;176(2):1035-47
references.pmid: 17409078
references.citation: Genetics. 1990 Nov;126(3):657-63
references.pmid: 2249764
references.citation: Genetics. 2006 Feb;172(2):1107-19
references.pmid: 16322521
references.citation: Mol Biol Evol. 2002 Dec;19(12):2261-4
references.pmid: 12446816
references.citation: Genetics. 1994 May;137(1):233-41
references.pmid: 8056313
references.citation: Bioinformatics. 1998;14(9):817-8
references.pmid: 9918953
references.citation: Genetics. 2004 Jun;167(2):835-50
references.pmid: 15238532
references.citation: Bioinformatics. 2003 Aug 12;19(12):1572-4
references.pmid: 12912839
references.citation: Bioinformatics. 2005 Jan 15;21(2):260-2
references.pmid: 15377507
references.citation: Mol Biol Evol. 1997 Sep;14(9):959-67
references.pmid: 9287429
references.citation: Curr Genet. 1993 Dec;24(6):539-43
references.pmid: 8299176
references.citation: Genetics. 2004 Feb;166(2):883-94
references.pmid: 15020473
references.citation: Mol Biol Evol. 2004 Dec;21(12):2319-25
references.pmid: 15342796
references.citation: Mol Ecol. 2003 Feb;12(2):447-61
references.pmid: 12535095
references.citation: Science. 2004 May 14;304(5673):981
references.pmid: 15143273
references.citation: Nature. 1994 Apr 28;368(6474):818
references.pmid: 8159241
references.citation: Genetics. 2006 Nov;174(3):1081-94
references.pmid: 16951056
references.citation: N Engl J Med. 2002 Aug 22;347(8):576-80
references.pmid: 12192017
references.citation: Genome Res. 1998 Mar;8(3):175-85
references.pmid: 9521921
references.citation: Proc Biol Sci. 2005 Apr 7;272(1564):697-704
references.pmid: 15870032
references.citation: Nucleic Acids Res. 1994 Nov 11;22(22):4673-80
references.pmid: 7984417
references.citation: Mol Biol Evol. 2005 Oct;22(10):2104-12
references.pmid: 15987876
references.citation: Bioinformatics. 2000 Jul;16(7):573-82
references.pmid: 11038328
references.citation: Mol Biol Evol. 2005 Mar;22(3):620-9
references.pmid: 15537802
references.citation: Mol Biol Evol. 2003 Feb;20(2):243-7
references.pmid: 12598691
references.citation: Curr Genet. 2001 Apr;39(2):117-24
references.pmid: 11405096
references.citation: J Mol Evol. 1992 Feb;34(2):126-9
references.pmid: 1556748
references.citation: Dev Growth Differ. 2007 Jan;49(1):67-72
references.pmid: 17227346
references.citation: Mol Ecol. 2005 Oct;14(11):3605-13
references.pmid: 16156827