The Fox genes of Branchiostoma floridae.
The Fox genes are united by encoding a fork head domain, a deoxyribonucleic acid (DNA)-binding domain of the winged-helix type that marks these genes as encoding transcription factors. Vertebrate Fox genes are classified into 23 subclasses named from FoxA to FoxS. We have surveyed the genome of the amphioxus Branchiostoma floridae, identifying 32 distinct Fox genes representing 21 of these 23 subclasses. The missing subclasses, FoxR and FoxS, are specific to vertebrates, and in addition, B. floridae has one further group, FoxAB, that is not found in vertebrates. Hence, we conclude B. floridae has maintained a high level of Fox gene diversity. Expressed sequence tag and complementary DNA sequence data support the expression of 23 genes. Several linkages between B. floridae Fox genes were noted, including some that have evolved relatively recently via tandem duplication in the amphioxus lineage and others that are more ancient.
Yu
Jr-Kai
JK
Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei 11529, Taiwan, Republic of China. jkyu@gate.sinica.edu.tw
Mazet
Francoise
F
Chen
Yen-Ta
YT
Huang
Song-Wei
SW
Jung
Kuo-Chen
KC
Shimeld
Sebastian M
SM
D000818:Animals; D002816:Chordata, Nonvertebrate / Q000235:genetics*; D019143:Evolution, Molecular; D051858:Forkhead Transcription Factors / Q000235:genetics*; D015870:Gene Expression; D010802:Phylogeny
D051858:Forkhead Transcription Factors
Gene. 2003 Oct 16;316:79-89
14563554
Dev Genes Evol. 1998 Oct;208(8):431-9
9799423
Cell. 1990 Nov 2;63(3):455-6
2225060
Dev Biol. 1997 Mar 1;183(1):74-85
9119116
Dev Dyn. 2004 Feb;229(2):357-66
14745961
Dev Dyn. 2002 Nov;225(3):289-97
12412011
BMC Genomics. 2006 Oct 24;7:271
17062144
Evol Dev. 2006 Mar-Apr;8(2):150-73
16509894
Bioinformatics. 2003 Aug 12;19(12):1572-4
12912839
Curr Biol. 2006 May 9;16(9):R314-6
16682334
Evol Dev. 2002 Jan-Feb;4(1):9-15
11868660
Dev Genes Evol. 2005 Dec;215(12):618-30
16193320
Dev Genes Evol. 2003 Mar;213(2):102-5
12632180
Dev Biol. 2002 Nov 15;251(2):258-70
12435356
Nucleic Acids Res. 1997 Dec 15;25(24):4876-82
9396791
Comput Appl Biosci. 1996 Aug;12(4):357-8
8902363
Dev Biol. 2006 Dec 1;300(1):49-62
17081512
Bioinformatics. 2001 Aug;17(8):754-5
11524383
Dev Genes Evol. 2003 Jun;213(5-6):314-8
12736826
Dev Genes Evol. 2003 Jun;213(5-6):235-44
12743820
Nature. 1993 Jul 29;364(6436):412-20
8332212
Genes Dev. 2000 Jan 15;14(2):142-6
10702024
Gene. 2000 Oct 3;256(1-2):29-34
11054532