[Study on the distribution and location of neuroglobin in human tissues and cells].
OBJECTIVE
To explore the distribution and location of neuroglobin (NGB) and its function in human tissues and cells.


METHODS
The distribution and localization of NGB in human tissues and cells were examined by immunohistochemical method.


RESULTS
NGB-positive cells were mainly distributed in neurons of central nervous system and peripheral nervous system, and some in endocrine tissues and genital system. NGB-immunoreactive product located in the cytoplasm of these cells.


CONCLUSIONS
The expression of NGB in human nervous tissues, some endocrine tissues and genital system suggested that NGB might play an important role in the utilizations of oxygen and physiological functions.
Qin
Hao-jie
HJ
Department of Forensic Pathology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Zhang
Lu-shun
LS
Wu
Na
N
Guo
Ya-dong
YD
Zhang
Lin
L
Li
Ming-yuan
MY
Guan
Peng
P
D000293:Adolescent; D000328:Adult; D005260:Female; D005914:Globins / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism* / Q000502:physiology; D009420:Nervous System / Q000166:cytology / Q000378:metabolism*; D000078787:Neuroglobin; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D010101:Oxygen Consumption / Q000502:physiology; D055815:Young Adult
D009419:Nerve Tissue Proteins; D000078787:Neuroglobin; D005914:Globins