title: Efficacy of adding 2% (w/v) chlorhexidine gluconate to 70% (v/v) isopropyl alcohol for skin disinfection prior to peripheral venous cannulation.
abstract: We undertook a clinical trial to compare the efficacy of 2% (w/v) chlorhexidine gluconate in 70% (v/v) isopropyl alcohol with the efficacy of 70% (v/v) isopropyl alcohol alone for skin disinfection to prevent peripheral venous catheter colonization and contamination. We found that the addition of 2% chlorhexidine gluconate reduced the number of peripheral venous catheters that were colonized or contaminated.
authors.affiliation: Department of Clinical Microbiology and Infection Control, University Hospital Birmingham NHS Foundation Trust, The Queen Elizabeth Hospital, Edgbaston, England.
authors.forename: Heather
authors.initials: H
authors.lastname: Small
authors.forename: Debra
authors.initials: D
authors.lastname: Adams
authors.forename: Anna L
authors.initials: AL
authors.lastname: Casey
authors.forename: Cynthia T
authors.initials: CT
authors.lastname: Crosby
authors.forename: Peter A
authors.initials: PA
authors.lastname: Lambert
authors.forename: Thomas
authors.initials: T
authors.lastname: Elliott
mesh_terms: D019840:2-Propanol / Q000494:pharmacology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002406:Catheterization, Peripheral / Q000379:methods; D002408:Catheters, Indwelling / Q000382:microbiology; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D004203:Disinfection / Q000379:methods*; D004866:Equipment Contamination / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000382:microbiology*; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; C010882:chlorhexidine gluconate; D019840:2-Propanol; D002710:Chlorhexidine