Multimarker panel in patients admitted to emergency department: a comparison with reference methods.
OBJECTIVE
Point of care testing and multimarker panels are rapidly expanding in emergency departments. We determined the reliability of Short-of-Breath SOB panel in patients admitted for acute dyspnea and/or chest pain.


METHODS
SOB D-dimer, BNP, cTnI, CK-MB and myoglobin assays were compared with references in 97 outpatients.


RESULTS
The correlation between SOB and references methods was acceptable, but with limited precision and accuracy.


CONCLUSIONS
Diagnostic performances and cut-off values should be further validated before clinicians replace traditional cardio-respiratory biomarkers by the new SOB panel.
Gruson
Damien
D
Department of Endocrinology and Nutrition, Unit of Diabetes and Nutrition, Cliniques Universitaires St-Luc, Brussels, Belgium. gruson_damien@yahoo.fr
Thys
Frédéric
F
Ketelslegers
Jean Marie
JM
Pasquet
Agnes
A
Delvau
Nicolas
N
Deneys
Véronique
V
Verschuren
Franck
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D002637:Chest Pain / Q000175:diagnosis*; D004417:Dyspnea / Q000175:diagnosis*; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019095:Point-of-Care Systems; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D015415:Biomarkers