title: Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose.
abstract: A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of intravenous sodium bicarbonate.
authors.affiliation: Hong Kong Poison Information Centre, Hong Kong. henrychanhy@yahoo.com
authors.forename: Ho Yin
authors.initials: HY
authors.lastname: Chan
authors.forename: Yiu Cheung
authors.initials: YC
authors.lastname: Chan
authors.forename: Fei Lung
authors.initials: FL
authors.lastname: Lau
mesh_terms: D000328:Adult; D000639:Amitriptyline / Q000506:poisoning*; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning*; D053840:Brugada Syndrome / Q000139:chemically induced*; D062787:Drug Overdose / Q000188:drug therapy; D004562:Electrocardiography; D006801:Humans; D008297:Male; D017693:Sodium Bicarbonate / Q000627:therapeutic use; D013405:Suicide
chemical_list: D000929:Antidepressive Agents, Tricyclic; D000639:Amitriptyline; D017693:Sodium Bicarbonate