title: Growth inhibition of Struvite crystals in the presence of juice of Citrus medica Linn.
abstract: Struvite, one of the components of urinary stone grows rapidly forming "staghorn-calculi", is a painful urological disorder. It is necessary to study the growth-inhibition of Struvite crystals. This in vitro study has been carried out in the presence of the juice of Citrus medica Linn. by using single diffusion gel growth technique. Sodium metasilicate solution of specific gravity 1.05 and an aqueous solution of ammonium dihydrogen phosphate of 0.5 M concentration were mixed so that the pH value 7.0 could be set. After the gelation, supernatant solutions comprising of pure 1.0 M Magnesium acetate (control solution) as well as mixed with the different concentrations of the juice were gently poured on the set gels. From the study of growth-inhibition behavior of Struvite crystals, it was found that Citrus medica Linn. inhibits the growth of the crystals. This study may be used for formulating the strategy for prevention or dissolution of Struvite.
authors.affiliation: Crystal Growth Laboratory, Department of Physics, Saurashtra University, Rajkot, 360 005, Gujarat, India. ckc33@rediffmail.com
authors.forename: C K
authors.initials: CK
authors.lastname: Chauhan
authors.forename: M J
authors.initials: MJ
authors.lastname: Joshi
mesh_terms: D002957:Citrus / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D017616:Magnesium Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D028321:Plant Preparations / Q000737:chemistry*; D000069877:Struvite
chemical_list: D017616:Magnesium Compounds; D010710:Phosphates; D028321:Plant Preparations; D000069877:Struvite
references.citation: Coll Antropol. 2003 Dec;27(2):745-52
references.pmid: 14746167
references.citation: Br J Urol. 1973 Dec;45(6):581-5
references.pmid: 4775736
references.citation: Nephrol Dial Transplant. 2000 Mar;15(3):366-74
references.pmid: 10692522
references.citation: Int Urol Nephrol. 1974;5(3):249-60
references.pmid: 4829131
references.citation: Endocrinol Metab Clin North Am. 2002 Dec;31(4):885-93, viii
references.pmid: 12474636
references.citation: Coll Antropol. 2003;27 Suppl 1:71-5
references.pmid: 12955895
references.citation: N Engl J Med. 1992 Oct 15;327(16):1141-52
references.pmid: 1528210
references.citation: J Urol. 1949 Feb;61(2):194-203
references.pmid: 18111841
references.citation: Kidney Int. 1978 May;13(5):372-82
references.pmid: 351265
references.citation: Vet Clin North Am Small Anim Pract. 1999 Jan;29(1):231-50, xiii-xiv
references.pmid: 10028160
references.citation: Urol Res. 2005 May;33(2):73-9
references.pmid: 15875173
references.citation: World J Urol. 1999 Oct;17(5):308-15
references.pmid: 10552150
references.citation: J Urol. 1995 Dec;154(6):2020-4
references.pmid: 7500448
references.citation: Urol Res. 2005 May;33(2):80-6
references.pmid: 15791467
references.citation: J Urol. 1995 Oct;154(4):1552-6
references.pmid: 7658589
references.citation: Invest Urol. 1978 May;15(6):438-41
references.pmid: 649290
references.citation: J Urol. 1986 Feb;135(2):397-401
references.pmid: 3944880
references.citation: Am J Kidney Dis. 1991 Apr;17(4):420-5
references.pmid: 2008910