Sclerosing therapy for orbital lymphangioma using sodium tetradecyl sulfate.
OBJECTIVE
To describe the results of intralesional injection of the sclerosing agent sodium tetradecyl sulfate in patients with orbital lymphangioma.


METHODS
Four young patients with a history of orbital lymphangioma were treated on one or more occasions with percutaneous puncture and injection of sodium tetradecyl sulfate under computed tomography guidance. Resolution of the signs and symptoms, complications resulting from surgery, and recurrence of bleeding were studied.


RESULTS
Three patients with a long-standing history of unilateral proptosis and one patient with progressive unilateral visual loss from multiple recurrent orbital hemorrhages were studied. Treatment ranged from one to three sodium tetradecyl sulfate injections. All patients showed improvement of their signs and symptoms after treatment. A decrease in the size of lesions was demonstrated by orbital imaging. Visual acuity and intraocular pressure remained unchanged. Complications included transient postoperative localized inflammation in all cases and transient ophthalmoparesis in one patient. Follow-up time ranged between 15 and 36 months, during which no recurrence of bleeding was observed.


CONCLUSIONS
Our study suggests that intralesional injection of sodium tetradecyl sulfate under computed tomography guidance is an effective treatment for patients with orbital lymphangioma and is not associated with vision-threatening complications.
Poonyathalang
Anuchit
A
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Preechawat
Pisit
P
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. akepisit@gmail.com.
Jiarakongmun
Pakorn
P
Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Pongpech
Sirintara
S
Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D007267:Injections; D007429:Intraocular Pressure; D008202:Lymphangioma / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D011677:Punctures; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D012981:Sodium Tetradecyl Sulfate / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014792:Visual Acuity
D012597:Sclerosing Solutions; D012981:Sodium Tetradecyl Sulfate
Am J Ophthalmol. 1986 Sep 15;102(3):308-14
3752195
Dermatol Surg. 2004 Dec;30(12 Pt 1):1454-6; discussion 1456
15606731
N C Med J. 1996 Jan-Feb;57(1):42-6
8821717
Ophthalmic Plast Reconstr Surg. 2001 Mar;17(2):85-90
11281596
Am J Ophthalmol. 1961 Mar;51:481-509
13790538
Br J Ophthalmol. 2000 Jun;84(6):614-7
10837387
Am J Ophthalmol. 2006 Feb;141(2):333-9
16458690
Ophthalmologica. 1991;203(4):161-3
1784461
Plast Reconstr Surg. 1999 Jul;104(1):1-11; discussion 12-5
10597669
Ophthalmology. 1990 Dec;97(12):1583-92
2087290
Ophthalmic Plast Reconstr Surg. 2004 Nov;20(6):463-5
15599249
AJNR Am J Neuroradiol. 2005 Nov-Dec;26(10):2630-4
16286413
Ophthalmic Plast Reconstr Surg. 1999 Nov;15(6):432-7
10588254
Interv Neuroradiol. 2001 Sep 30;7(3):193-9
20663348