title: Your diagnosis? A 12-year-old girl with latent tuberculosis presenting with nausea, vomiting and increasing frontal headache.
abstract: A 12-year-old girl with latent Mycobacterium tuberculosis infection and currently receiving prophylaxis with isoniazid presented with nausea, vomiting and increasing frontal headache. Toxicity to the anti-tuberculosis drug was suspected, but her symptoms persisted after isoniazid withdrawal. A computed tomography (CT) scan showed a brain mass to be present.
authors.affiliation: Department of Paediatrics, University of Florence, Anna Meyer Children's Hospital, via Luca Giordano 13, 50132 Florence, Italy.
authors.forename: Marina
authors.initials: M
authors.lastname: De Gaudio
authors.forename: Elena
authors.initials: E
authors.lastname: Chiappini
authors.forename: Piera
authors.initials: P
authors.lastname: Catania
authors.forename: Federico
authors.initials: F
authors.lastname: Mussa
authors.forename: Luisa
authors.initials: L
authors.lastname: Galli
authors.forename: Maurizio
authors.initials: M
authors.lastname: de Martino
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage* / Q000009:adverse effects; D008527:Medulloblastoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009325:Nausea / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000517:prevention & control; D014839:Vomiting / Q000209:etiology*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid
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