[Ocular ochronosis. A case report].
Ochronosis or alkaptonuria is a rare inherited disease. It is characterized by the deposition of dark pigments in collagen-rich tissues, which leads to clinical manifestations such as arthropathy. The ochronotic pigment can be found in the sclera, the conjunctiva, and the limbic cornea. Vision is usually not affected. We report the case of 47-year-old patient who complained of lower back pain. Ophthalmologic examination showed dark pigments in the conjunctiva. The increased levels of homogentisic acid in urine confirmed the diagnosis of ochronosis.
Ben Rayana
N
N
Service d'Ophtalmologie, Centre Hospitalo-Universitaire Farhat Hached, Sousse, Tunisie. narjesbenrayana@yahoo.fr
Chahed
N
N
Khochtali
S
S
Ghorbel
M
M
Hamdi
R
R
Rouis
M
M
Bouajina
I
I
Hamida
F Ben Hadj
FB
D001706:Biopsy; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology; D003228:Conjunctiva / Q000473:pathology*; D006713:Homogentisic Acid / Q000032:analysis* / Q000652:urine; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000473:pathology; D017116:Low Back Pain / Q000000981:diagnostic imaging / Q000209:etiology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009794:Ochronosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D011859:Radiography; D012590:Sclera / Q000473:pathology; D012880:Skin Pigmentation; D013128:Spinal Osteophytosis / Q000000981:diagnostic imaging / Q000209:etiology*
D006713:Homogentisic Acid