Lack of association between MTHFR C677T and MTHFR A1298C genetic polymorphisms and mental retardation.
Findings suggest that there is no association between MTHFR C677T and MTHFR A1298C and mental retardation in the studied Italian population and that these polymorphisms are not contributing to the aetiology of mental retardation.
Saccucci
Patrizia
P
Division of Human Population and Environmental Pathology, Department of Biopathology and Imaging Diagnostics, University of Rome Tor Vergata, Rome, Italy. saccucci@med.uniroma2.it
Compagnone
Eliana
E
Verrotti
Alberto
A
Galasso
Cinzia
C
Curatolo
Paolo
P
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D020022:Genetic Predisposition to Disease; D006801:Humans; D008607:Intellectual Disability / Q000201:enzymology / Q000235:genetics*; D007558:Italy; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
D042965:Methylenetetrahydrofolate Reductase (NADPH2)