Novel biomarkers for predicting preeclampsia.
Preeclampsia is a major cause of maternal morbidity and mortality worldwide. Despite decades of research into the condition, the ability of clinicians to predict preeclampsia prior to the onset of symptoms has not improved significantly. In this review, we will examine the pathophysiology underlying preeclampsia and will look at potential biomarkers for early prediction and diagnosis. In addition, we will explore potential future areas of research into the condition.
Carty
David M
DM
BHF Glasgow Cardiovascular Research Centre, University of Glasgow, G12 8TA Glasgow, United Kingdom.
Delles
Christian
C
Dominiczak
Anna F
AF
D028341:Activins / Q000378:metabolism; D043925:Angiogenesis Inducing Agents / Q000378:metabolism; D015703:Antigens, CD / Q000378:metabolism; D001057:Apolipoproteins E / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism*; D000071063:Endoglin; D005260:Female; D006801:Humans; D007265:Inhibins / Q000378:metabolism; D007333:Insulin Resistance; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000503:physiopathology; D011247:Pregnancy; D011266:Pregnancy-Associated Plasma Protein-A / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D040281:Vascular Endothelial Growth Factor Receptor-1 / Q000378:metabolism
D043925:Angiogenesis Inducing Agents; D015703:Antigens, CD; D001057:Apolipoproteins E; D015415:Biomarkers; C064206:ENG protein, human; D000071063:Endoglin; D011956:Receptors, Cell Surface; C422405:activin A; C422362:inhibin A; D028341:Activins; D007265:Inhibins; C501162:FLT1 protein, human; D040281:Vascular Endothelial Growth Factor Receptor-1; C430889:PAPPA2 protein, human; D011266:Pregnancy-Associated Plasma Protein-A
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