Cytotoxic constituents from the bark of Salix hulteni.
Eight compounds were isolated from the bark of Salix hulteni. Based on spectral data, the isolated compounds were identified as 4-hydroxyacetophenone (1), naringenin (2), aromadendrin (3), catechin (4), picein (5), sachaliside 1 (6), 1-p-coumaroyl-beta-D-glucoside (7), and dihydromyricetin (8). Their cytotoxic activities against brine shrimp and a human lung cancer cell line (H1299) were evaluated.
Jeon
Seong Ho
SH
College of Pharmacy, Kangwon National University, Chuncheon 200-701, Korea.
Chun
Wanjoo
W
Choi
Yong Joon
YJ
Kwon
Yong Soo
YS
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D001156:Artemia; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D006868:Hydrolysis; D008175:Lung Neoplasms / Q000188:drug therapy; D013058:Mass Spectrometry; D024301:Plant Bark / Q000737:chemistry; D032108:Salix / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013778:Tetrazolium Salts; D013844:Thiazoles
D000972:Antineoplastic Agents, Phytogenic; D013778:Tetrazolium Salts; D013844:Thiazoles; C022616:thiazolyl blue