[An adolescent case of pulmonary MAC infection, found 3 years later from bone marrow transplantation for myelodysplastic syndrome].
Mycobacterium avium complex (MAC) pulmonary infection is usually seen in elderly persons. We encountered a rare case of MAC pulmonary disease seen in a 19-year-old adolescent. The patient had received bone marrow transplantation at the age of 16 for myelodysplastic syndrome. Subsequently, he developed constrictive bronchiolitis and has been treated with corticosteroid and taclorimus. At age 19, small or fine nodules and a cavitary nodule in right lung were detected on the chest radiograph and computed tomography. Afterwards, Mycobacterium avium was detected by bronchoscopic examination and sputum examination and he was diagnosed as MAC pulmonary infection. MAC pulmonary infection in a young person at the age of 19 is an extremely rare case, in which constrictive bronchiolitis, immunosuppression by corticosteroid and tacrolimus, and diabetes mellitus were considered as critical predisposing factors.
Minamoto
Seijiro
S
Clinical Research Center, National Hospital Organization Kinki-chuo Chest Medical Center, 1180 Nagasone-cho, Kita-ku, Sakai-shi, Osaka 591-8555, Japan. minamoto@kch.hosp.go.jp
Tsuyuguchi
Kazunari
K
Suzuki
Katsuhiro
K
Okada
Masaji
M
Sakatani
Mitsunori
M
D000328:Adult; D016026:Bone Marrow Transplantation; D006801:Humans; D008297:Male; D015270:Mycobacterium avium-intracellulare Infection / Q000209:etiology*; D009190:Myelodysplastic Syndromes / Q000601:surgery*; D011183:Postoperative Complications; D012307:Risk Factors; D014397:Tuberculosis, Pulmonary / Q000209:etiology*