Malignancies in renal transplant patients: 15 years experience in Thailand.
The increased incidence of malignancies post-renal transplantation is well established. We performed a retrospective review of the 270 renal transplant patients from May 1, 1992 to April 30, 2007, including 18 cases (6.7%) of malignancy. The most common cancer in the study was transitional cell carcinoma of the urinary tract (7/18). The second most common cancer was hepatocellular carcinoma (3/18). In contrast to reports from Caucasian countries, we found only 2/18 patients had posttransplantation lymphoproliferative disease and no report of skin cancer. Among the 18 patients with malignancy, 11 died (mortality rate = 61%). We encourage a more extensive study of malignancy post-renal transplantation at multiple centers with a tumor registry in Thailand.
Ativitavas
T
T
Division of Medical Oncology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. touchat100@hotmail.com
Jirasiritham
S
S
Ngorsakun
P
P
Pipatpannawong
K
K
Mavichak
V
V
D002102:Cadaver; D005260:Female; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D019520:Living Donors / Q000706:statistics & numerical data; D008297:Male; D009369:Neoplasms / Q000453:epidemiology*; D012189:Retrospective Studies; D013785:Thailand; D014019:Tissue Donors / Q000706:statistics & numerical data