title: Effect of binary combination of deltamethrin+MGK-264 on the levels of phospholipid and lipid peroxidation in the snail Lymnaea acuminata.
abstract: Effect of sublethal treatment of (40% and 60% of 48 h LC50) of deltamethrin+MGK on phospholipid level and rate of lipid peroxidation in nervous and foot tissue of Lymnaea acuminata were studied. Maximum reduction in phospholipid (24.10%) level and increase in rate of lipid peroxidation (586.8%) were observed in foot tissue of snail exposed to 60% of 48 h LC50 of deltamethrin+MGK 264 for 96 h. Alterations in the levels of phospholipids and rate of lipid peroxidation were time and concentration dependent. Use of MGK-264 with deltamethrin increases the toxicity of deltamethrin and their action on membrane phospholipids and rate of lipid peroxidation.
authors.affiliation: Department of Zoology, DDU Gorakhpur University, Gorakhpur, UP 273 009, India.
authors.forename: R N
authors.initials: RN
authors.lastname: Singh
authors.forename: Pradeep
authors.initials: P
authors.lastname: Kumar
authors.forename: V K
authors.initials: VK
authors.lastname: Singh
authors.forename: D K
authors.initials: DK
authors.lastname: Singh
mesh_terms: D000818:Animals; D007306:Insecticides / Q000494:pharmacology / Q000633:toxicity*; D054833:Isoindoles / Q000494:pharmacology / Q000633:toxicity*; D007928:Lethal Dose 50; D015227:Lipid Peroxidation / Q000187:drug effects*; D008195:Lymnaea / Q000187:drug effects*; D009417:Nerve Tissue / Q000737:chemistry; D009570:Nitriles / Q000494:pharmacology / Q000633:toxicity*; D009636:Norbornanes / Q000494:pharmacology / Q000633:toxicity*; D010743:Phospholipids / Q000378:metabolism*; D011722:Pyrethrins / Q000494:pharmacology / Q000633:toxicity*; D013997:Time Factors
chemical_list: D007306:Insecticides; D054833:Isoindoles; D009570:Nitriles; D009636:Norbornanes; D010743:Phospholipids; D011722:Pyrethrins; C004371:N-(2-ethylhexyl)-5-norbornene-2,3-dicarboxamide; C017180:decamethrin