title: Molecular characterization of a variant of Bacillus anthracis-specific phage AP50 with improved bacteriolytic activity.
abstract: The genome sequence of a Bacillus anthracis-specific clear plaque mutant phage, AP50c, contains 31 open reading frames spanning 14,398 bp, has two mutations compared to wild-type AP50t, and has a colinear genome architecture highly similar to that of gram-positive Tectiviridae phages. Spontaneous AP50c-resistant B. anthracis mutants exhibit a mucoid colony phenotype.
authors.affiliation: Naval Medical Research Center, Silver Spring, Maryland 20910, USA. Shanmuga.Sozhamannan@med.navy.mil
authors.forename: Shanmuga
authors.initials: S
authors.lastname: Sozhamannan
authors.forename: Michael
authors.initials: M
authors.lastname: McKinstry
authors.forename: Shannon M
authors.initials: SM
authors.lastname: Lentz
authors.forename: Matti
authors.initials: M
authors.lastname: Jalasvuori
authors.forename: Farrell
authors.initials: F
authors.lastname: McAfee
authors.forename: Angela
authors.initials: A
authors.lastname: Smith
authors.forename: Jason
authors.initials: J
authors.lastname: Dabbs
authors.forename: Hans-W
authors.initials: HW
authors.lastname: Ackermann
authors.forename: Jaana K H
authors.initials: JK
authors.lastname: Bamford
authors.forename: Alfred
authors.initials: A
authors.lastname: Mateczun
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Read
mesh_terms: D017103:Bacillus Phages / Q000235:genetics*; D001408:Bacillus anthracis / Q000821:virology*; D001433:Bacteriolysis; D001483:Base Sequence; D004279:DNA, Viral / Q000235:genetics*; D023061:Gene Order; D016679:Genome, Viral; D008969:Molecular Sequence Data; D020125:Mutation, Missense; D017354:Point Mutation; D017422:Sequence Analysis, DNA; D026801:Synteny; D017916:Tectiviridae / Q000235:genetics; D010948:Viral Plaque Assay; D014771:Virion / Q000648:ultrastructure
chemical_list: D004279:DNA, Viral
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