Familial dysbetalipoproteinemia: a potentially fatal disorder.
Familial dysbetalipoproteinemia is an inherited disorder in which both cholesterol and triglycerides are elevated in the plasma of the blood, which pre-disposes people to coronary artery disease and peripheral vascular disease. We report two young boys with multiple cutaneous xanthomas and grossly abnormal serum cholesterol and triglycerides. Two of the family members had died of cardiovascular accidents in young age and rest of the family members had deranged lipid profile. Patients were managed with lipid lowering drugs and fat restriction diet. All family members were counseled and advised regular exercise and follow-up.
Bari
Arfan Ul
AU
Department of Dermatology, Combined Military Hospital, Peshawar, Pakistan. albariul@gmail.com
Hashim
Rizwan
R
Rahman
Simeen Ber
SB
Hussain
Majid
M
D000293:Adolescent; D000328:Adult; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D000069059:Atorvastatin; D015248:Gemfibrozil / Q000627:therapeutic use; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D006952:Hyperlipoproteinemia Type III / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008297:Male; D011758:Pyrroles / Q000627:therapeutic use; D012307:Risk Factors
D000924:Anticholesteremic Agents; D006538:Heptanoic Acids; D000960:Hypolipidemic Agents; D011758:Pyrroles; D000069059:Atorvastatin; D015248:Gemfibrozil