title: Head-to-head comparison of an automated immunometric and an automated HPLC method for the quantification of HbA1c.
abstract: OBJECTIVE
  To compare a fully automated immunoassay and a fully automated HPLC method for the quantification of HbA1c.
  
  
  METHODS
  For an inter-method comparison, 200 consecutive clinical samples were analyzed. Imprecision was studied with pooled whole blood.
  
  
  RESULTS
  Very close agreement of results (identical mean result (6.0%); r=0.99), and very similar reproducibility (total CV approximately 1%) were observed.
  
  
  CONCLUSIONS
  Both assays offer very similar analytical performance, although the analytical techniques used are completely different.
authors.affiliation: Institute of Clinical Chemistry, University of Munich, Marchioninistrabetae 15, D-81377 Munich, Germany. Michael.Vogeser@med.uni-muenchen.de
authors.forename: Michael
authors.initials: M
authors.lastname: Vogeser
authors.forename: Klaus G
authors.initials: KG
authors.lastname: Parhofer
mesh_terms: D001331:Automation; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007118:Immunoassay / Q000379:methods*
chemical_list: D006442:Glycated Hemoglobin