title: Shift work and its effects on the cardiovascular system.
abstract: The practice of shift-work scheduling has long been part of normal work duties in emergency services such as health and security. It is only recently, in the wake of growing job opportunities and booming industries, where more employees are needed to keep services running over 24-hour periods that studies on the effects of shift work on workers' health have begun to delve deeper. The desynchronisation that occurs in circadian rhythms, with respect to sleep cycles, predisposes employees to coronary heart disease, gastrointestinal disturbances, increased risk of breast cancer and poor pregnancy outcomes. This literature review focuses on circadian rhythms, their molecular components, disturbances of these rhythms as a result of shift work and the adverse effects thereof on the cardiovascular system.
authors.affiliation: Reproductive Health and HIV Research Unit, Johannesburg. tmosendane@rhru.co.za
authors.forename: T
authors.initials: T
authors.lastname: Mosendane
authors.forename: T
authors.initials: T
authors.lastname: Mosendane
authors.forename: F J
authors.initials: FJ
authors.lastname: Raal
mesh_terms: D035843:Biomedical Research; D002319:Cardiovascular System / Q000378:metabolism / Q000503:physiopathology*; D002940:Circadian Rhythm; D015986:Confounding Factors, Epidemiologic; D050171:Dyslipidemias / Q000503:physiopathology; D018149:Glucose Intolerance / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D009765:Obesity / Q000503:physiopathology; D009784:Occupational Diseases / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D010561:Personnel Staffing and Scheduling; D012107:Research Design; D015398:Signal Transduction; D020178:Sleep Disorders, Circadian Rhythm / Q000503:physiopathology; D014940:Work Schedule Tolerance
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