title: [Current status of researches in the development of blood tissue engineering product].
abstract: The term "blood substitutes" includes plasma substitutes and blood cell substitutes in the broad sense, but in its narrow sense, it means red blood cell (RBC) substitutes, platelet substitutes and white blood cell (WBC) substitutes. The RBC substitutes includes perfluorocarbon, hemoglobin-based and encapsuled substitutes. The hemoglobin-based substitutes which was widely researched in the world includes human hemoglobin-based, animal hemoglobin-based and gene recombined hemoglobin based substitutes. The function and immunology of WBC is very complicated, so it is rarely used in clinic. Nowadays the platelet substitutes pursued by the researches and developments includes mainly the liposome and collagenic fiber species substitutes.
authors.affiliation: College of Pharmaceuticals and Technology, Tianjin University, Tianjin 300071, China. lifengjuan12@163.com
authors.forename: Fengjuan
authors.initials: F
authors.lastname: Li
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Wang
authors.forename: Chengmin
authors.initials: C
authors.lastname: Yang
mesh_terms: D001802:Blood Substitutes / Q000138:chemical synthesis*; D005466:Fluorocarbons / Q000737:chemistry; D006454:Hemoglobins / Q000737:chemistry; D006801:Humans; D011994:Recombinant Proteins / Q000737:chemistry; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D001802:Blood Substitutes; D005466:Fluorocarbons; D006454:Hemoglobins; D011994:Recombinant Proteins