title: Histologic study of the effect of laser therapy on bone repair.
abstract: OBJECTIVE
  This study used histologic analysis and HE staining to evaluate laser biomodulation of bone repair in cavities made in the femurs of rats that underwent non-ablative laser irradiation.
  
  
  METHODS
  Eighteen male Wistar rats weighing 300 to 400 grams were randomly assigned to three groups of six animals each. A surgical defect site was produced with a trephine about 2 mm in diameter under abundant irrigation. In Group I the complete surgical protocol to produce a bone defect was followed but without laser radiation (control). In Group II a continuous wave 830 nm infrared laser was used at 10 J/cm2 and 50 mW at each point of the surgical site. In Group III a continuous wave 685 nm infrared laser at 10J/cm2 and 35 mW was used at each point of surgical site. The animals were irradiated at intervals of 48 hours beginning immediately after the preparation of the defect and were sacrificed on the 15th, 21st, and 30th days. Slides were studied by means of descriptive analysis.
  
  
  RESULTS
  Greater degrees of new bone formation and vertical regeneration were found in the irradiated groups than in the control group.
  
  
  CONCLUSIONS
  Laser therapy in this study protocol was efficient in promoting bone repair.
  
  
  CONCLUSIONS
  The use of laser technology has been used to improve the clinical results of bone surgeries and to promote a more comfortable postoperative period and quicker healing.
authors.affiliation: Centro Universitário Franciscano, Santa Maria, RS, Brazil.
authors.forename: Diego Segatto
authors.initials: DS
authors.lastname: Blaya
authors.forename: Micéli Beck
authors.initials: MB
authors.lastname: Guimarães
authors.forename: Daniel Humberto
authors.initials: DH
authors.lastname: Pozza
authors.forename: João Batista Blessmann
authors.initials: JB
authors.lastname: Weber
authors.forename: Marília Gerhardt
authors.initials: MG
authors.lastname: de Oliveira
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000528:radiation effects*; D005269:Femur / Q000601:surgery; D007259:Infrared Rays; D007834:Lasers; D028022:Low-Level Light Therapy; D008297:Male; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D014945:Wound Healing / Q000528:radiation effects*