[How I treat... paracetamol poisoning].
Drug self-poisoning is a common cause of admission in ED. Among various incriminated substances, paracetamol is often implicated and presents a severe toxicity. We briefly describe the epidemiology and physiopathology of paracetamol self-poisoning. We then clarify the diagnostic elements, thresholds of toxicity, indications for treatment and different available therapeutic guidelines.
Bertrand
X
X
Service des Urgences, CHU ND des Bruyères, Liège.
Brasseur
E
E
Ghuysen
A
A
D'Orio
V
V
D000082:Acetaminophen / Q000493:pharmacokinetics / Q000506:poisoning*; D018712:Analgesics, Non-Narcotic / Q000493:pharmacokinetics / Q000506:poisoning*; D000931:Antidotes / Q000627:therapeutic use*; D006801:Humans; D011041:Poisoning / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D017410:Practice Guidelines as Topic
D018712:Analgesics, Non-Narcotic; D000931:Antidotes; D000082:Acetaminophen