title: Nucleosides with 1,4-dioxane as sugar moiety.
abstract: A synthetic route towards novel nucleosides with 1,4- dioxane as the sugar moiety has been developed. The dioxane moiety features a second anomeric center, which has been phosphitylated giving a diastereomeric mixture of the corresponding phosphoramidites.
authors.affiliation: Nucleic Acid Center, Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark. asm@ifk.sdu.dk
authors.forename: Andreas Stahl
authors.initials: AS
authors.lastname: Madsen
authors.forename: Niels
authors.initials: N
authors.lastname: Langkjaer
authors.forename: Jesper
authors.initials: J
authors.lastname: Wengel
mesh_terms: D004146:Dioxanes / Q000737:chemistry*; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004146:Dioxanes; D009705:Nucleosides; D009943:Organophosphorus Compounds; C434331:phosphoramidite; C025223:1,4-dioxane