title: Volumizing effect of a new hyaluronic acid sub-dermal facial filler: a retrospective analysis based on 102 cases.
abstract: BACKGROUND
  Many signs of aging are due to the loss of subcutaneous fat. Dermal fillers are non-surgical cosmetic treatments used to restore facial volume. Voluma is a new hyaluronic acid sub-dermal facial filler. The objective of this study was to assess its effectiveness in maintaining increased volume for up to 18 months post-treatment and its safety.
  
  
  METHODS
  Retrospective record analysis was made for 102 patients (93 females, nine males; mean age: 51.27 years) who received Voluma injected into the midface. All patients were assessed at baseline and at 1 month and 6-18 months post-injection.
  
  
  RESULTS
  Investigator Global Aesthetic Improvement assessment after 1 month and 6-18 months showed that most patients were 'much' or 'very much' improved. Investigator volume loss assessment confirmed that most patients were either stage 1 or 2 (normal or slight ptosis) 1 month post-treatment, which was maintained at 6-18 months. Patient efficacy assessment was 'very good' or 'good' in most cases.
  
  
  CONCLUSIONS
  Voluma provides aesthetic improvements according to investigator and patient assessment for up to 18 months post-treatment. Combination treatment comprising facial fillers and botulinum neurotoxin can enhance treatment benefits. Further methodologically rigorous studies are required to establish the performance of Voluma alone and in combination.
authors.affiliation: Palais Armenonville, Rond Point Duboys d'Angers, Cannes, France. raspaldo@clinic.com.fr
authors.forename: Hervé
authors.initials: H
authors.lastname: Raspaldo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D003357:Cosmetic Techniques; D020405:Dermis; D005145:Face; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007267:Injections; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D006820:Hyaluronic Acid