title: [Correlation between syndrome factor combination and cardiac function as well as blood-lipid in coronary heart disease].
abstract: OBJECTIVE
  To discuss the distribution laws of traditional Chinese medicine (TCM) syndrome factor and their combination in coronary heart disease (CHD), and to study the correlation between the TCM syndrome factor combination and cardiac function as well as blood-lipid.
  
  
  METHODS
  The parameters of the cardiac function of 300 patients with a final diagnosis of CHD by coronary angiography were measured by echocardiography, and the levels of blood lipids in the CHD patients were detected. An analysis of the correlation was done between the TCM syndrome factor combination and cardiac function as well as blood-lipid in CHD.
  
  
  RESULTS
  The TCM syndrome factor combinations of CHD were blood stasis due to qi deficiency, qi and yin deficiency, intermingled phlegm and blood stasis, and yang deficiency and blood stasis. The ejection fraction of CHD patients with yang deficiency and blood stasis was markedly decreased. The levels of triglyceride and low-density lipoprotein cholesterol in CHD patients with intermingled phlegm and blood stasis were markedly increased, and the level of triglyceride in CHD patients with qi and yin deficiency was markedly increased too.
  
  
  CONCLUSIONS
  The treatment of CHD should aim directly at the symptoms and causes. It is also proved that some compound traditional Chinese herbal medicines for supplementing qi and activating blood circulation, nourishing yin and resolving phlegm, and activating yang should be used in treatment of CHD. In cases of CHD with low cardiac function, particular emphasis should be laid on activating yang and blood circulation, while in cases of CHD with blood-lipid disturbance, particular emphasis should be laid on resolving phlegm and activating blood circulation, replenishing qi and nourishing yin.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Qing-Yong
authors.initials: QY
authors.lastname: He
authors.forename: Zhan
authors.initials: Z
authors.lastname: Shi
authors.forename: Yan-Wei
authors.initials: YW
authors.lastname: Xing
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: Fang
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Tang
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D013577:Syndrome
chemical_list: D004365:Drugs, Chinese Herbal; D008055:Lipids