New and efficient synthesis of nucleoside polyphosphates and nucleoside monophosphate sugars.
A new and efficient method for the synthesis of nucleoside di- and triphosphates, dinucleoside tetraphosphates and nucleoside monophosphate sugars is described. This new route is based on cycloSal-nucleosyl-phosphate triesters as active ester that underlie fast conversion to the corresponding products.
Warnecke
Svenja
S
Organic Chemistry, Department of Chemistry, Faculty of Science, University of Hamburg, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany.
Meier
Chris
C
D001671:Biochemistry / Q000379:methods; D015226:Dinucleoside Phosphates / Q000138:chemical synthesis / Q000737:chemistry; D009711:Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D009712:Nucleotides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D011122:Polyphosphates / Q000737:chemistry*
D015226:Dinucleoside Phosphates; D009711:Nucleotides; D009712:Nucleotides, Cyclic; D011122:Polyphosphates; C019509:nucleoside monophosphate sugars