Risk factors for methicillin-resistant Staphylococcus aureus surgical site infection.
We prospectively evaluated 46 possible risk factors for methicillin-resistant Staphylococcus aureus (MRSA) surgical site infection (SSI) among patients with MRSA carriage in a large intervention study. Of 6,130 study patients, 68 (1.1%) developed MRSA SSI, which occurred a median of 14 days after surgery. Risk factors associated with MRSA SSI were receipt of emergency surgery, presence of comorbid condition, receipt of immunosuppressive therapy, receipt of contaminated surgery, and a surgical duration longer than the 75th percentile. MRSA carriage on admission did not predict MRSA SSI.
Harbarth
Stephan
S
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland. stephan.harbarth@hcuge.ch
Huttner
Benedikt
B
Gervaz
Pascal
P
Fankhauser
Carolina
C
Chraiti
Marie-Noelle
MN
Schrenzel
Jacques
J
Licker
Marc
M
Pittet
Didier
D
D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000382:microbiology; D013557:Switzerland / Q000453:epidemiology; D013997:Time Factors