title: Changes in cardiac parameters of renal allograft recipients: a compilation of clinical, laboratory, and echocardiographic observations.
abstract: BACKGROUND
  This study was undertaken to observe changes in cardiac parameters along with clinical and laboratory changes after renal transplantation.
  
  
  METHODS
  Cardiac parameters were evaluated by M-mode 2-dimensional echocardiography before transplantation and at monthly intervals. All subjects had functioning grafts at the time of the evaluations.
  
  
  RESULTS
  Fifty-two allograft recipients underwent pretransplant parameters for comparison to those at posttransplant months 1, 3, 6, and 12. When changes at month 1 and 3 were observed among 22 patients, improvements were evident at month 3. Comparisons of pretransplant versus month 3 showed systolic blood pressure (SBP), 161 +/- 16 to 133 +/- 26 mmHg (P < .002); diastolic BP (DBP), 101 +/- 9 to 86 +/- 11 mmHg, (P < .006); hemoglobin (Hgb), 7.3 +/- 1.6 to 11.2 +/- 3.9 g/dL (P < .006); left atrial diameter (LAD), 41 +/- 5 to 35 +/- 3 mm (P < .001); left ventricular muscle mass index (LVMI), 379 +/- 114 to 248 +/- 58 g/m2 (P < .001); and left ventricular end diastolic volume index (LVEDVI), 96 +/- 28 to 64 +/- 17 mL/m2 (P < .002). When changes at months 3, 6, and 12 were observed among 30 patients, improvements evident at month 3 were maintained. Comparisons of pretransplant and 3 and 12 months observations showed SBP, 157 +/- 17, 131 +/- 14, to 126 +/- 10 mm Hg (P < .001); DBP, 97 +/- 10, 83 +/- 16, to 85 +/- 6 mmHg (P < .001); Hgb, 7 +/- 1, 13 +/- 2, to 13 +/- 2 g/dL (P < .001); LAD, 39 +/- 7, 35 +/- 3, to 34 +/- 4 mm (P < .05); LVMI, 275 +/- 91, 191 +/- 38, to 159 +/- 26 g/m2 (P < .001); and LVEDVI, 87 +/- 29, 56 +/- 34, to 49 +/- 24 mL/m2 (P < .001).
  
  
  CONCLUSIONS
  Significant improvements in cardiac parameters were evident by the third month post-renal transplantation; the changes were maintained over a longer period among patients with functional grafts.
authors.affiliation: Department of Nephrology, SSMC&MH, Bangladesh. masud_1232001@yahoo.com
authors.forename: M M
authors.initials: MM
authors.lastname: Iqbal
authors.forename: H U
authors.initials: HU
authors.lastname: Rashid
authors.forename: S K
authors.initials: SK
authors.lastname: Banerjee
authors.forename: M H
authors.initials: MH
authors.lastname: Rahman
authors.forename: M
authors.initials: M
authors.lastname: Mohsin
mesh_terms: D000328:Adult; D000740:Anemia / Q000209:etiology; D001794:Blood Pressure; D004452:Echocardiography; D005500:Follow-Up Studies; D006325:Heart Atria / Q000033:anatomy & histology / Q000503:physiopathology; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000503:physiopathology; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects / Q000502:physiology*; D011183:Postoperative Complications / Q000503:physiopathology; D014184:Transplantation, Homologous; D014664:Vasodilation; D016276:Ventricular Function; D016277:Ventricular Function, Left