Noxa upregulation is associated with apoptosis of chronic lymphocytic leukemia cells induced by hyperforin but not flavopiridol.
Zaher
M
M
Akrout
I
I
Mirshahi
M
M
Kolb
J-P
JP
Billard
C
C
D000911:Antibodies, Monoclonal / Q000276:immunology; D017209:Apoptosis / Q000187:drug effects*; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology; D005419:Flavonoids / Q000494:pharmacology*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood / Q000235:genetics / Q000473:pathology*; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000502:physiology; D010696:Phloroglucinol / Q000031:analogs & derivatives* / Q000494:pharmacology; D010880:Piperidines / Q000494:pharmacology*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D013729:Terpenes / Q000494:pharmacology*; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000473:pathology; D015854:Up-Regulation / Q000187:drug effects
D000911:Antibodies, Monoclonal; D001643:Bridged Bicyclo Compounds; D005419:Flavonoids; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins; C498702:PMAIP1 protein, human; D010880:Piperidines; D019253:Proto-Oncogene Proteins c-bcl-2; D013729:Terpenes; C077990:alvocidib; D010696:Phloroglucinol; C001654:hyperforin