title: Comparison of ultrasound-guided core-needle biopsy and fine-needle aspiration in the assessment of head and neck lesions.
abstract: BACKGROUND
  Core-needle biopsy (CNB) has been successfully applied in other medical specialties, but its value is undetermined in otolaryngology.
  
  
  METHODS
  This prospective study includes 75 patients, who were seen at our institution with a cervical mass. The results of CNB were compared with those of fine-needle aspiration (FNA) in the 68 histologically verified cases.
  
  
  RESULTS
  CNB was superior to FNA providing a specific diagnosis (90% vs 66%) and achieved a higher accuracy in identifying true neoplasms (100% vs 93%) and detecting malignancy (99% vs 90%). However, the sensitivity and specificity did not differ significantly between both methods.
  
  
  CONCLUSIONS
  Sonography and if necessary FNA should continue to be the investigation method of first choice for head and neck lesions. The main indication for CNB is after repeated failures of FNA to provide a diagnosis. It can also be performed in patients who are not surgical candidates or in those who refuse surgery.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Kantonsspital Aarau, Aarau, Switzerland. marcel.kraft@gmx.ch
authors.forename: Marcel
authors.initials: M
authors.lastname: Kraft
authors.forename: Hubert
authors.initials: H
authors.lastname: Laeng
authors.forename: Nicolas
authors.initials: N
authors.lastname: Schmuziger
authors.forename: André
authors.initials: A
authors.lastname: Arnoux
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gürtler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle / Q000379:methods*; D001707:Biopsy, Needle / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013557:Switzerland; D018084:Ultrasonography, Interventional