title: Allometric scaling of echocardiographic measurements in healthy Spanish foals with different body weight.
abstract: Scaling in biology is usually allometric, and therefore, the size of the heart may be expressed as a power function of body weight (BW). The present research analyses the echocardiographic measurements in 68 healthy Spanish foals weighed between 70 and 347kg in order to determine the correct scaling exponent for the allometric equation. The echocardiographic parameters measured were: left ventricular internal dimensions (LVID), free wall thickness (LVFWT), interventricular septum thickness (IVST) at systole (s) and diastole (d), EPSS (distance between the point E of the mitral valve and the interventricular septum), and aorta diameters at the level of the aortic valve (AOD), base of valve leaflets (ABS), sinus of Valsalva (ASV) and sino-tubular junction (AJT). Indices of left ventricular performance were calculated. It was found that LVIDd, IVSTs, AOD, and ASV have a relationship to BW raised to 0.300-0.368 power, whereas left ventricular end-diastolic volume and stroke volume scaled to BW raised to 0.731-0.712 power. With these data, appropriate values can be calculated for normal Spanish foals.
authors.affiliation: Department of Animal Medicine and Surgery, Cardenal Herrera-CEU University, Avda. Seminario CEU s/n, 46113 Moncada, Valencia, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Rovira
authors.forename: A
authors.initials: A
authors.lastname: Muñoz
authors.forename: V
authors.initials: V
authors.lastname: Rodilla
mesh_terms: D000818:Animals; D001835:Body Weight / Q000502:physiology*; D004452:Echocardiography / Q000379:methods / Q000662:veterinary*; D005260:Female; D006321:Heart / Q000502:physiology*; D006736:Horses / Q000502:physiology*; D016014:Linear Models; D008297:Male; D012016:Reference Values