title: Tuberculous effusive-constrictive pericarditis.
abstract: Infection with Mycobacterium tuberculosis and the human immunodeficiency virus has reached epidemic proportions in South Africa. Cardiac involvement occurs in approximately one per cent of patients suffering from active tuberculosis. This concerns predominantly pericardial involvement, resulting in chronic pericardial effusions, cardiac tamponade and constrictive pericarditis. Effusive-constrictive pericarditis is a clinical haemodynamic syndrome in which constriction by the visceral pericardium occurs in the presence of a tense effusion in a free pericardial space. We present a patient who was diagnosed with this condition, and highlight the value of contrast-enhanced magnetic resonance imaging in demonstrating the underlying structural and functional abnormalities.
authors.affiliation: Department of Internal Medicine, Groote Schuur Hospital and University of Cape Town, Observatory.
authors.forename: J B
authors.initials: JB
authors.lastname: Russell
authors.forename: F F
authors.initials: FF
authors.lastname: Syed
authors.forename: M
authors.initials: M
authors.lastname: Ntsekhe
authors.forename: B M
authors.initials: BM
authors.lastname: Mayosi
authors.forename: S
authors.initials: S
authors.lastname: Moosa
authors.forename: M
authors.initials: M
authors.lastname: Tshifularo
authors.forename: J P
authors.initials: JP
authors.lastname: Smedema
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010490:Pericardial Effusion / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D010494:Pericarditis, Constrictive / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D010495:Pericarditis, Tuberculous / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000995:Antitubercular Agents