title: Prostatic remnants in mature cystic teratoma of the ovary.
abstract: Mature cystic teratomas of the ovary containing prostatic remnants are reported in 2 women aged 31 and 20 years. Both cases showed the expected histology of mature teratomas with a mixture of ecto- and endodermal structures lying in a fibrous stroma. In both cases, the foci of prostate tissue were composed of typical prostatic glands arranged in acinar structures. One case displayed a transitional cell-lined duct resembling the urethra. Prostate glands showed intense positive immunostaining with prostatic specific antigen and prostatic acidic phosphatase. Focal images suggesting high-grade prostatic intraepithelial neoplasia were detected in 1 case. The literature on this unusual finding in these common tumors is reviewed and commented on.
authors.affiliation: Department of Anatomic Pathology, Hospital de Basurto, Basque Country University, Bilbao, Bizkaia, Spain. garelli@euskalnet.net
authors.forename: José I
authors.initials: JI
authors.lastname: López
authors.forename: Itziar Sáenz
authors.initials: IS
authors.lastname: de Santamaría
authors.forename: Ignacio J
authors.initials: IJ
authors.lastname: Claros
authors.forename: Maddi
authors.initials: M
authors.lastname: Garmendia
authors.forename: Ayman
authors.initials: A
authors.lastname: Gaafar
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Bilbao
mesh_terms: D000135:Acid Phosphatase; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D011467:Prostate / Q000737:chemistry / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000032:analysis; D019048:Prostatic Intraepithelial Neoplasia / Q000737:chemistry / Q000473:pathology; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology; D017027:Protein Tyrosine Phosphatases / Q000032:analysis; D013724:Teratoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D000135:Acid Phosphatase; C428439:prostatic acid phosphatase; D017027:Protein Tyrosine Phosphatases; D017430:Prostate-Specific Antigen