title: The significance of potassium chloride sensitivity test and urinary uronic acid level in the diagnosis of chronic pelvic pain syndrome.
abstract: OBJECTIVE
  Noninvasive tests are needed for the diagnosis of chronic pelvic pain syndrome. We evaluated the significance of potassium chloride sensitivity test and urinary CTAB-precipitable uronate level in patients with chronic pelvic pain syndrome (CPPS).
  
  
  METHODS
  We included 25 patients with interstitial cystitis (IC), and 30 patients with chronic prostatitis (CP) who applied to our outpatient clinic with the complaints of frequency, dysuria and pain on urination between the years 2003 and 2005. Thirty-five subjects were studied as healthy controls. All patients underwent cystoscopy, cystometry, voiding diary, sodium chloride, and potassium chloride filling tests. Visual analog scale (VAS) was used to determine pain scores. Patients with CP also underwent NaCl and KCl voiding tests. Urinary CTAB-precipitable uronate levels were obtained in all subjects.
  
  
  RESULTS
  KCl test had a good sensitivity for IC. As for the patients with CP, KCl voiding test was useful, but KCl filling test was not. Urinary CTAB-precipitable uronate level was found to be significantly higher in patients with IC and CP than controls, and in patients with IC than in patients with CP.
  
  
  CONCLUSIONS
  The results of our study suggest that KCl voiding test is a good candidate to be used in the diagnostic workup of patients with category III CP, and urinary CTAB-precipitable uronate level measurement may be a noninvasive diagnostic aid for IC and CP.
authors.affiliation: Department of Urology, Maresal Cakmak Hospital, Erzurum, Turkey.
authors.forename: Bilal Firat
authors.initials: BF
authors.lastname: Alp
authors.forename: Ilker
authors.initials: I
authors.lastname: Akyol
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Adayener
authors.forename: Temucin
authors.initials: T
authors.lastname: Senkul
authors.forename: Mustafa
authors.initials: M
authors.lastname: Gultepe
authors.forename: Kadir
authors.initials: K
authors.lastname: Baykal
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Iseri
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000379:methods*; D011189:Potassium Chloride; D011472:Prostatitis / Q000175:diagnosis* / Q000652:urine*; D014574:Uronic Acids / Q000652:urine*
chemical_list: D014574:Uronic Acids; D011189:Potassium Chloride
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