title: The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations.
abstract: The novel pyrimidine (3-6) and purine (12-19) acyclic nucleoside analogues containing (Z) 4-amino or 4-aminohydrochloride-2-butenyl side chain (Fig.) were synthesized to evaluate their antiviral and cytostatic activity potency.
authors.affiliation: Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
authors.forename: Karlo
authors.initials: K
authors.lastname: Wittine
authors.forename: Kresimir
authors.initials: K
authors.lastname: Benci
authors.forename: Sandra Kraljević
authors.initials: SK
authors.lastname: Pavelić
authors.forename: Kresimir
authors.initials: K
authors.lastname: Pavelić
authors.forename: Mladen
authors.initials: M
authors.lastname: Mintas
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D054697:Cytostatic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D054697:Cytostatic Agents; D011684:Purine Nucleosides; D011741:Pyrimidine Nucleosides