title: Signet-ring cell carcinoma of the jejunum diagnosed by double balloon enteroscopy.
abstract: The small bowel rarely develops neoplasms, accounting for only 1-2% of all gastrointestinal neoplasms. Most cases of jejunal and ileal adenocarcinoma are of well or moderately differentiated type, and other types are rare. This study reports a rare case of signet-ring cell carcinoma of the jejunum diagnosed by double balloon enteroscopy. The patient was a 79-year-old woman who complained of passing tarry stool. Esophagogastroduodenoscopy and total colonoscopy yielded no evidence of gastrointestinal bleeding. Small intestinal barium study demonstrated stenosis with pocket formation in the middle portion of the jejunum. Double balloon enteroscopy was performed to identify the cause of stenosis. Double balloon enteroscopy showed stenosis of the middle portion of the jejunum with pocket formation. The surface of the stenotic portion was covered with shallow ulcerations, but was not markedly irregular. Histologically, the lesion was found to be a signet-ring cell carcinoma of the jejunum. Formation of a lesion of this type may be associated with a rare type of histological morphology such as signet-ring cell carcinoma. The endoscopic findings are important in diagnosing such lesions, and are useful in distinguishing them from other diseases.
authors.affiliation: Department of Gastroenterology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. yamagami@med.osaka-cu.ac.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Yamagami
authors.forename: Nobuhide
authors.initials: N
authors.lastname: Oshitani
authors.forename: Takehisa
authors.initials: T
authors.lastname: Suekane
authors.forename: Kazuki
authors.initials: K
authors.lastname: Aomatsu
authors.forename: Noriko
authors.initials: N
authors.lastname: Kamata
authors.forename: Mitsue
authors.initials: M
authors.lastname: Sogawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Watanabe
authors.forename: Eiji
authors.initials: E
authors.lastname: Noda
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ikura
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Maeda
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Arakawa
mesh_terms: D000368:Aged; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology* / Q000601:surgery; D002404:Catheterization; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007580:Jejunal Neoplasms / Q000473:pathology* / Q000601:surgery