title: A study to evaluate the feasibility of an aerobic exercise program in patients with migraine.
abstract: OBJECTIVE
  The aim of this study was to develop and evaluate an exercise program to improve maximum oxygen uptake (VO(2 max)) in untrained patients with migraine without making their migraines worse.
  
  
  METHODS
  Twenty-six patients were studied at a headache clinic in Sweden. The exercise program, based on indoor cycling, was performed 3 times per week during 12 weeks. VO(2 max), migraine status, side effects, and quality of life were evaluated.
  
  
  RESULTS
  VO(2 max) increased from 32.9 mL/kg/minute to 36.2 mL/kg/minute (P = .044). Quality of life increased and significant improvements in migraine status (attack frequency, symptom intensity, and intake of medicine) were seen. During the 12 weeks of exercise, on one occasion one patient had a migraine attack, which started immediately after training. No other side effects were reported.
  
  
  CONCLUSIONS
  The evaluated exercise program was well tolerated by the patients and improved their VO(2 max) with no deterioration of migraine status.
authors.affiliation: Cephalea Headache Centre, Gothenburg, Sweden.
authors.forename: Emma
authors.initials: E
authors.lastname: Varkey
authors.forename: Asa
authors.initials: A
authors.lastname: Cider
authors.forename: Jane
authors.initials: J
authors.lastname: Carlsson
authors.forename: Mattias
authors.initials: M
authors.lastname: Linde
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy*; D010101:Oxygen Consumption / Q000502:physiology*; D011788:Quality of Life; D013548:Sweden / Q000453:epidemiology