A new HLA-DR4 allele, DRB1*0474, with an unusual residue at position 77.
We report here a new DR4 allele, DRB1*0474, identified in a volunteer hematopoietic stem cell donor of the Swiss National Registry. DRB1*0474 differs from DRB1*040701 by two nucleotide residues resulting in a single Thr --> Asn substitution at codon 77.
Desaules
C
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National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, University Hospital, Geneva, Switzerland.
Villard
J
J
Tiercy
J-M
JM
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D015804:HLA-DR4 Antigen / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D015804:HLA-DR4 Antigen