Management of diffuse glioma in children: a retrospective study of 27 cases and review of literature.
Gliomas are the most common CNS tumours in children and present either as circumscribed tumours or diffusely infiltrative neoplasms. Diffuse gliomas develop both in the cerebral hemispheres and the brainstem and have a poor prognosis. Guidelines for the therapy of these tumours are still debated. In this study, we reviewed the clinical features of 27 consecutive patients with diffuse gliomas admitted to the Department of Paediatrics of CHR Citadelle, University of Liège, between 1985 and 2005. We review their clinical presentation, diagnosis, treatment and outcome with reference to the published literature.
Piette
Caroline
C
Department of Paediatrics, CHR Citadelle, University of Liège, Belgium. caroline.piette@ulg.ac.be
Deprez
Manuel
M
Born
Jacques
J
Michotte
Alex
A
Munaut
Carine
C
Closon
Marie-Thérèse
MT
Rutten
Isabelle
I
Dresse
Marie-Françoise
MF
Forget
Patricia
P
Schmitz
Véronique
V
Misson
Jean-Paul
JP
Hoyoux
Claire
C
D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D019635:Neurosurgical Procedures; D012189:Retrospective Studies
D000970:Antineoplastic Agents