Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate.
A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.
Cui
Sun-Liang
SL
Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China.
Wang
Jing
J
Wang
Yan-Guang
YG
D000577:Amides / Q000737:chemistry*; D003979:Diazonium Compounds / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000577:Amides; D003979:Diazonium Compounds; D007211:Indoles; C032111:diazoacetic ester