title: Three-dimensional spectral domain optical coherence tomography of a clear corneal cataract incision.
abstract: A prototype 1,310-nm wavelength spectral domain optical coherence tomography (SD-OCT) instrument was constructed and mounted onto a conventional slit lamp for imaging of the anterior segment. The device had an axial resolution of 8 microm and was able to acquire real-time two-dimensional images at 14 frames/second and full three-dimensional datasets in approximately 7 seconds. An SD-OCT dataset of 100 B-scans, each consisting of 512 A-scans, was acquired from the left eye ofa patient who had undergone phacoemulsification with a clear corneal incision. The resulting dataset could be manipulated in three-dimensional space to analyze the geometry of the wound. Additionally, stromal edema and iris features were clearly imaged with the device. SD-OCT can be used to analyze clear corneal incisions to determine optimal wound construction technique and geometry as they relate to the prevention of complications such as postoperative wound leak, infection, and epithelial ingrowth.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors.forename: Theodore
authors.initials: T
authors.lastname: Leng
authors.forename: Brandon J
authors.initials: BJ
authors.lastname: Lujan
authors.forename: Sonia H
authors.initials: SH
authors.lastname: Yoo
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
mesh_terms: D000369:Aged, 80 and over; D003315:Cornea / Q000166:cytology* / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D018918:Phacoemulsification / Q000379:methods*; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*
references.citation: Opt Lett. 2003 Oct 1;28(19):1745-7
references.pmid: 14514087
references.citation: J Cataract Refract Surg. 2004 Aug;30(8):1781-5
references.pmid: 15313307
references.citation: J Cataract Refract Surg. 2005 Apr;31(4):643-5
references.pmid: 15899418
references.citation: J Cataract Refract Surg. 2007 Jan;33(1):94-7
references.pmid: 17189800
references.citation: J Cataract Refract Surg. 2007 Aug;33(8):1429-35
references.pmid: 17662437
references.citation: Am J Ophthalmol. 2005 Jun;139(6):983-7
references.pmid: 15953426
references.citation: Opt Lett. 2004 Mar 1;29(5):480-2
references.pmid: 15005199
references.citation: Cornea. 2006 Sep;25(8):960-5
references.pmid: 17102675