title: Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Schafer
authors.forename: Rani
authors.initials: R
authors.lastname: Sellers
authors.forename: Erio
authors.initials: E
authors.lastname: Barale-Thomas
mesh_terms: D000818:Animals; D015197:Carcinogenicity Tests / Q000379:methods*; D002273:Carcinogens / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D064420:Drug-Related Side Effects and Adverse Reactions; D009929:Organ Size; D010338:Pathology, Clinical; D018570:Risk Assessment; D012377:Rodentia; D036401:Toxicity Tests, Chronic / Q000379:methods*
chemical_list: D002273:Carcinogens