title: [Latissimus dorsi myocutaneous flap in the surgical treatment of locally advanced breast cancer].
abstract: Locally advanced breast cancer (LABC) usually have a poor prognosis. In some cases surgical treatment is not performed at all due to technical problem: mastectomy defect closure. Even all additional forms of treatment are involved there is a little chance to reduce a huge tumor mass and get tumor growing under control.
  
  
  METHODS
  We present a case of LABC in 46-year woman with history of three-year breast cancer (T4NxMI - supraclavicular).
  
  
  RESULTS
  Because of tumor formation in left breast and pathologically confirmed left supracla-vicular lymph node metastasis at 2003, the whole course of neoadjvant therapy was performed - including radio and chemotherapy. With signs of new spread of disease the patient was admitted in 3rd Surgical Clinic, Medical University - Plovdiv. After a proper preoperative preparation the patient was operated. The ontological part of procedure involved simple mastectomy during which the soft tissues 34/14 cm defect was occurred. In the reconstructive phase of the operation a LDF was disained and with additional V-Y-plasty the mastectomy defect was completely covered.
  
  
  CONCLUSIONS
  1. Even with a poor prognosis the LABC must by a surgical case in order to maximum tumor mass redusing. 2. LDF is a technical possible way for postmasrectomy soft tissue defect reconstruct-tion. 3. It is necessity to include the LDF in a earlier treatment stage.
authors.forename: V
authors.initials: V
authors.lastname: Molov
authors.forename: P
authors.initials: P
authors.lastname: Tepavicharova
authors.forename: G
authors.initials: G
authors.lastname: Deenichin
authors.forename: Ch
authors.initials: Ch
authors.lastname: Stefanov
authors.forename: P
authors.initials: P
authors.lastname: Mandev
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D016462:Mammaplasty / Q000379:methods*; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000601:surgery*; D009361:Neoplasm Invasiveness; D013524:Surgical Flaps; D016896:Treatment Outcome