title: DNA glue: 1-, 2- and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids (TINAs), DNA duplexes/triplexes and interstrand excimer formation.
abstract: Significant alterations in thermal stability of parallel DNA triplexes and antiparallel duplexes were observed upon changing the attachment of ethynylpyrenes from para to ortho in the structure of phenylmethylglycerol inserted as a bulge into DNA (TINA). Insertions of two ortho-TINAs as a pseudo-pair in the middle of the duplex resulted in formation of an excimer band at 505 nm for both 1- and 4-ethynylpyrene analogues.
authors.affiliation: Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand. v.filichev@massey.ac.nz
authors.forename: Vyacheslav V
authors.initials: VV
authors.lastname: Filichev
authors.forename: Irina V
authors.initials: IV
authors.lastname: Astakhova
authors.forename: Andrei D
authors.initials: AD
authors.lastname: Malakhov
authors.forename: Vladimir A
authors.initials: VA
authors.lastname: Korshun
authors.forename: Erik B
authors.initials: EB
authors.lastname: Pedersen
mesh_terms: D004247:DNA / Q000737:chemistry*; D007364:Intercalating Agents / Q000737:chemistry*; D009691:Nucleic Acid Denaturation; D011721:Pyrenes / Q000737:chemistry*; D013696:Temperature
chemical_list: D007364:Intercalating Agents; D011721:Pyrenes; C051802:triplex DNA; D004247:DNA