Synthesis of some derivatives of 3'-C-methyl pyrimidine nucleosides.
Attempts for the synthesis of 2'-deoxy-2'-fluoro nucleoside derivative of 3'-C-methyluridine were reported. The corresponding parent nucleoside was chosen as the starting material. However, the 2'-deoxy-2'-fluoro nucleoside was not obtained. Nevertheless, the new and unexpected nucleoside derivatives obtained as well as some proposals of mechanism regarding their formation will be presented.
Aljarah
Mohamed
M
Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-UM 1-UM 2, Université Montpellier 2, case courrier 1705, Place E. Bataillon, 34095 Montpellier cedex 05, France.
Mathé
Christophe
C
Périgaud
Christian
C
D014529:Uridine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
D014529:Uridine