title: [Sternal resection and chest wall reconstruction for primitive neuroectodermal tumor of the sternum].
abstract: Primitive neuroectodermal tumor of the sternum is rare. A 59-year-old woman referred to our department with anterior chest pain and a tumor in the sternum. The patient was diagnosed as primitive neuroectodermal tumor of the sternum by core biopsy of the lesion. She received 2 cycles of preoperative chemotherapy with vincristine, doxorubicin, cyclophosphamide, ifosfamide, etoposide. She underwent a total sternectomy with resection of adjacent bilateral costal cartilages and sternal ends of the clavicles. The skeletal defect of chest wall was reconstructed by polypropylene mesh-resin sandwich. The myocutaneus defect was reconstructed by the pedicled latissimus dorsi myocutaneus flap and the bilateral breast flaps. The postoperative course was uneventful and adjuvant radiotherapy was started 6 weeks after the operation. She died of distant metastases 3 months after the operation, although this patient was free from local recurrence.
authors.affiliation: Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Oishi
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumura
authors.forename: I
authors.initials: I
authors.lastname: Ishida
authors.forename: T
authors.initials: T
authors.lastname: Sado
authors.forename: Y
authors.initials: Y
authors.lastname: Hoshikawa
authors.forename: T
authors.initials: T
authors.lastname: Kondo
authors.forename: M
authors.initials: M
authors.lastname: Tachi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001426:Bacterial Proteins; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D026901:Membrane Transport Proteins; D008875:Middle Aged; D018242:Neuroectodermal Tumors, Primitive / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D019651:Plastic Surgery Procedures; D013249:Sternum / Q000601:surgery*; D013899:Thoracic Neoplasms / Q000601:surgery*; D019616:Thoracic Surgical Procedures; D035441:Thoracic Wall / Q000601:surgery*
chemical_list: D001426:Bacterial Proteins; C071991:FatB protein, Vibrio anguillarum; D026901:Membrane Transport Proteins