Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa.
Adolescents globally are at high risk for HIV acquisition and are the targets of HIV prevention interventions such as HIV vaccines. In order to understand stakeholders' attitudes towards the ethical issues of adolescent involvement in HIV vaccine trials, we conducted focus group discussions with key members of a semi-urban, informal Cape Town community with high HIV prevalence in which HIV vaccine trials are taking place. Themes were identified from focus group transcripts by four researchers, and included necessity of guardian consent, age of independent consent, and confidentiality of in-trial medical results. In general, ethical adolescent HIV vaccine trials will be feasible in this community.
Jaspan
Heather B
HB
Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa. hbjaspan@hotmail.com
Soka
Nosiphiwo F
NF
Strode
Ann E
AE
Mathews
Catherine
C
Mark
Daniella
D
Flisher
Alan J
AJ
Wood
Robin
R
Bekker
Linda-Gail
LG
D016915:AIDS Vaccines / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D026688:Bioethical Issues; D002986:Clinical Trials as Topic; D003159:Community-Institutional Relations; D003219:Confidentiality; D005260:Female; D017144:Focus Groups; D006801:Humans; D007258:Informed Consent; D008297:Male; D018579:Patient Selection; D035842:Research Subjects / Q000523:psychology; D013019:South Africa; D055815:Young Adult
D016915:AIDS Vaccines
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