A versatile one-pot procedure to phosphate monoesters and pyrophosphates using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite.
A one-pot procedure for the preparation of phosphoramidates, phosphorothioates, pyrophosphates, phosphodiesters, and phosphofluoridates has been devised using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite as the common phosphitylating reagent.
van der Heden van Noort
Gerbrand J
GJ
Leiden Institute of Chemistry, Leiden Unversity, PO Box 9502, 2300 RA Leiden, The Netherlands.
Verhagen
Carlo P
CP
van der Horst
Maarten G
MG
Overkleeft
Herman S
HS
van der Marel
Gijsbert A
GA
Filippov
Dmitri V
DV
D011756:Diphosphates / Q000737:chemistry*; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*
D011756:Diphosphates; D004952:Esters; D009943:Organophosphorus Compounds; C533293:di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite