Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report.
In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis -induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.
Soares
Sérgia
S
Division of Neonatology, Department of Pediatrics, Hospital São João, Porto, Portugal.
Rocha
Gustavo
G
Pissarra
Susana
S
Carriço
Ana
A
Azevedo
Inês
I
Sobrinho Simões
Joana
J
Guimarães
Hercília
H
D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000188:drug therapy; D007231:Infant, Newborn; D008297:Male; D012074:Remission Induction; D012720:Severity of Illness Index; D014917:Whooping Cough / Q000150:complications* / Q000188:drug therapy