title: Evidences of parasite evolution after vaccination.
abstract: We present a brief review of some of the empirical evidence of parasite evolution in response to vaccination. The available data shows that very different pathogen strategies can be selectively favored as a result of vaccination. However, this data often lacks a qualitative and/or quantitative assessment of the benefits and the costs associated with these alternative strategies. Without this type of information to calibrate theoretical models it will be difficult to predict the potential risks associated with vaccine-induced evolution. Our purpose here is therefore to stimulate future research into quantifying these effects.
authors.affiliation: CEFE-UMR 5175, 1919 Route de Mende, F-34293 Montpellier Cedex 5, France. sylvain.gandon@cefe.cnrs.fr
authors.forename: Sylvain
authors.initials: S
authors.lastname: Gandon
authors.forename: Troy
authors.initials: T
authors.lastname: Day
mesh_terms: D000818:Animals; D005075:Biological Evolution; D006790:Host-Parasite Interactions; D006801:Humans; D009154:Mutation; D010271:Parasites / Q000235:genetics*; D010272:Parasitic Diseases / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control*; D014611:Vaccination; D014612:Vaccines / Q000008:administration & dosage
chemical_list: D014612:Vaccines