title: Ru(III)-catalyzed oxidation of pyridoxine and albuterol in pharmaceuticals.
abstract: Ru(III) complexes with coordinated amide were synthesized and characterized by elemental, IR, mass, electronic, ESR spectral analysis, magnetic and conductance measurements and octahedral structures have been proposed. These complexes were used as catalysts for the oxidation of pyridoxine and albuterol in pharmaceuticals in presence of hydrogen peroxide. The role of co-oxidant and the effect of reaction time on the yields of oxidation products which were spectrophotometrically determined by condensing them with sulfanilic acid in acid medium were investigated. Structures of the oxidation products were established with the help of IR and NMR spectral analysis.
authors.affiliation: Department of Chemistry, Kakatiya University, Warangal 506 009, India.
authors.forename: More
authors.initials: M
authors.lastname: Ashok
authors.forename: Adapa V S S
authors.initials: AV
authors.lastname: Prasad
authors.forename: P Muralidhar
authors.initials: PM
authors.lastname: Reddy
authors.forename: Vadde
authors.initials: V
authors.lastname: Ravinder
mesh_terms: D000420:Albuterol / Q000737:chemistry*; D000577:Amides / Q000737:chemistry; D019817:Benzoic Acid / Q000737:chemistry; D002384:Catalysis; D003116:Color; D004578:Electron Spin Resonance Spectroscopy; D008280:Magnetics; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D011730:Pyridoxal / Q000737:chemistry; D011736:Pyridoxine / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013425:Sulfanilic Acids / Q000737:chemistry
chemical_list: D000577:Amides; D004364:Pharmaceutical Preparations; D013425:Sulfanilic Acids; D011730:Pyridoxal; D012428:Ruthenium; D019817:Benzoic Acid; D011736:Pyridoxine; D000420:Albuterol