title: Nonstoichiometric gelation of cyclodextrins and included planar guests.
abstract: A generic family of low molecular weight binary gels comprising beta-cyclodextrin (beta-CD) and one of a large variety of polyaromatic hydrocarbons (PAHs) in dimethylformamide (DMF), pyridine, and other polar solvents is described. The system is rather general and robust. It tolerates large changes in each of the major ingredients without losing gelation ability. alpha- and gamma-CD, and negatively or positively modified beta-CD (e.g., sulfate-, phosphate-, or amine-tethered beta-CD) as well as methylated beta-CD are all effective gelators. The cogelators encompass a similarly large variety of compounds characterized by the ability to form an ovular inclusion complex with the CD molecules and a capability to stack outside the CD cap to give long-range order far from the CD cap. Despite the low ratio between the CD and the cogelators, we show that most of the CD molecules are retained in the liquid phase and do not participate directly in the actual construction of the gel network. In fact, most of the sulfated and phosphated beta-CDs can be cleaned off the gel structure by electrophoresis, leaving an intact gel porous structure. The nonstoichiometric nature of the gel is underscored by the fact that one molecule of beta-CD can combine with as few as three molecules of chrysene or as many as 450 molecules of chrysene to gelate an additional 35,000-40,000 molecules of the solvent.
authors.affiliation: The Casali Institute and the NMR Laboratory, Institute of Chemistry, The Hebrew University of Jerusalem, Edmond E. Safra Givat Ram Campus, Jerusalem, 91904 Israel.
authors.forename: Dan
authors.initials: D
authors.lastname: Rizkov
authors.forename: Shaul
authors.initials: S
authors.lastname: Mizrahi
authors.forename: Jenny
authors.initials: J
authors.lastname: Gun
authors.forename: Roy
authors.initials: R
authors.lastname: Hoffman
authors.forename: Artem
authors.initials: A
authors.lastname: Melman
authors.forename: Ovadia
authors.initials: O
authors.lastname: Lev