title: Evaluation of a symptom diagram for identifying carpal tunnel syndrome.
abstract: BACKGROUND
  Hand symptom diagrams (HSDs) for rating the distribution of paraesthesias are proposed for use in epidemiological studies of carpal tunnel syndrome (CTS).
  
  
  OBJECTIVE
  To assess the validity of HSDs in a working population of manufacturing and service workers participating in a prospective study of musculoskeletal disorders.
  
  
  METHODS
  Assessment of each subject involved completing a HSD, a heath assessment and electrodiagnostic studies (EDSs). HSDs were rated for CTS blinded to the health assessment and EDS results. The validity assessments of HSD used EDS as the sole confirmatory standard for CTS.
  
  
  RESULTS
  A total of 733 subjects (65% of those eligible) participated in the study and 720 underwent EDSs. Dominant hand prevalence of a positive HSD and delayed nerve conduction studies in this working population was 9.2 per 100 workers. The sensitivity of a positive HSD for all workers was 0.28. By restricting the population to those workers with any current hand symptoms or to any worker with neuropathic hand symptoms, the sensitivities of HSD improved to 0.61 and 0.79, respectively. The positive predictive value of a HSD, with our study prevalence, was 0.48.
  
  
  CONCLUSIONS
  The HSD classification schema has poor validity when applied to a general working population but improves when applied to workers with current neuropathic symptoms. The high number of false-negative HSDs in the general study population is most likely to be due to the inadequacies of using EDS as the confirmatory test. With a low prevalence of CTS, the positive predictive value for HSDs is poor.
authors.affiliation: Safety and Health Assessment and Research for Prevention (SHARP) Program, Washington State Department of Labor and Industries, Olympia, WA 98504-4330, USA. bone235@lni.wa.gov
authors.forename: David K
authors.initials: DK
authors.lastname: Bonauto
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Silverstein
authors.forename: Z Joyce
authors.initials: ZJ
authors.lastname: Fan
authors.forename: Caroline K
authors.initials: CK
authors.lastname: Smith
authors.forename: Dana N
authors.initials: DN
authors.lastname: Wilcox
mesh_terms: D000293:Adolescent; D000328:Adult; D002349:Carpal Tunnel Syndrome / Q000175:diagnosis*; D004568:Electrodiagnosis; D005260:Female; D006225:Hand; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D009784:Occupational Diseases / Q000175:diagnosis*; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D055815:Young Adult