title: Management of diffuse glioma in children: a retrospective study of 27 cases and review of literature.
abstract: Gliomas are the most common CNS tumours in children and present either as circumscribed tumours or diffusely infiltrative neoplasms. Diffuse gliomas develop both in the cerebral hemispheres and the brainstem and have a poor prognosis. Guidelines for the therapy of these tumours are still debated. In this study, we reviewed the clinical features of 27 consecutive patients with diffuse gliomas admitted to the Department of Paediatrics of CHR Citadelle, University of Liège, between 1985 and 2005. We review their clinical presentation, diagnosis, treatment and outcome with reference to the published literature.
authors.affiliation: Department of Paediatrics, CHR Citadelle, University of Liège, Belgium. caroline.piette@ulg.ac.be
authors.forename: Caroline
authors.initials: C
authors.lastname: Piette
authors.forename: Manuel
authors.initials: M
authors.lastname: Deprez
authors.forename: Jacques
authors.initials: J
authors.lastname: Born
authors.forename: Alex
authors.initials: A
authors.lastname: Michotte
authors.forename: Carine
authors.initials: C
authors.lastname: Munaut
authors.forename: Marie-Thérèse
authors.initials: MT
authors.lastname: Closon
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rutten
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Dresse
authors.forename: Patricia
authors.initials: P
authors.lastname: Forget
authors.forename: Véronique
authors.initials: V
authors.lastname: Schmitz
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Misson
authors.forename: Claire
authors.initials: C
authors.lastname: Hoyoux
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D019635:Neurosurgical Procedures; D012189:Retrospective Studies
chemical_list: D000970:Antineoplastic Agents