Growth inhibition of Struvite crystals in the presence of juice of Citrus medica Linn.
Struvite, one of the components of urinary stone grows rapidly forming "staghorn-calculi", is a painful urological disorder. It is necessary to study the growth-inhibition of Struvite crystals. This in vitro study has been carried out in the presence of the juice of Citrus medica Linn. by using single diffusion gel growth technique. Sodium metasilicate solution of specific gravity 1.05 and an aqueous solution of ammonium dihydrogen phosphate of 0.5 M concentration were mixed so that the pH value 7.0 could be set. After the gelation, supernatant solutions comprising of pure 1.0 M Magnesium acetate (control solution) as well as mixed with the different concentrations of the juice were gently poured on the set gels. From the study of growth-inhibition behavior of Struvite crystals, it was found that Citrus medica Linn. inhibits the growth of the crystals. This study may be used for formulating the strategy for prevention or dissolution of Struvite.
Chauhan
C K
CK
Crystal Growth Laboratory, Department of Physics, Saurashtra University, Rajkot, 360 005, Gujarat, India. ckc33@rediffmail.com
Joshi
M J
MJ
D002957:Citrus / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D017616:Magnesium Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D028321:Plant Preparations / Q000737:chemistry*; D000069877:Struvite
D017616:Magnesium Compounds; D010710:Phosphates; D028321:Plant Preparations; D000069877:Struvite
Coll Antropol. 2003 Dec;27(2):745-52
14746167
Br J Urol. 1973 Dec;45(6):581-5
4775736
Nephrol Dial Transplant. 2000 Mar;15(3):366-74
10692522
Int Urol Nephrol. 1974;5(3):249-60
4829131
Endocrinol Metab Clin North Am. 2002 Dec;31(4):885-93, viii
12474636
Coll Antropol. 2003;27 Suppl 1:71-5
12955895
N Engl J Med. 1992 Oct 15;327(16):1141-52
1528210
J Urol. 1949 Feb;61(2):194-203
18111841
Kidney Int. 1978 May;13(5):372-82
351265
Vet Clin North Am Small Anim Pract. 1999 Jan;29(1):231-50, xiii-xiv
10028160
Urol Res. 2005 May;33(2):73-9
15875173
World J Urol. 1999 Oct;17(5):308-15
10552150
J Urol. 1995 Dec;154(6):2020-4
7500448
Urol Res. 2005 May;33(2):80-6
15791467
J Urol. 1995 Oct;154(4):1552-6
7658589
Invest Urol. 1978 May;15(6):438-41
649290
J Urol. 1986 Feb;135(2):397-401
3944880
Am J Kidney Dis. 1991 Apr;17(4):420-5
2008910