title: Nontraumatic keratomycosis caused by Alternaria in a glaucoma patient.
abstract: A case of keratomycosis caused by Alternaria species in a patient with glaucoma is reported. A 55-year-old Japanese man who had been followed for developmental glaucoma presented with corneal ulcer in his right eye, which did not respond to antibacterial agents. There was no history of traumatic episode. Culture on potato dextrose agar from corneal scraping yielded Alternaria species. Topical amphotericin B treatment achieved recovery from ulceration although the corneal opacity remained.
authors.affiliation: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. tomohiko-tky@umin.ac.jp
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Usui
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Misawa
authors.forename: Norihiko
authors.initials: N
authors.lastname: Honda
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tomidokoro
authors.forename: Satoru
authors.initials: S
authors.lastname: Yamagami
authors.forename: Shiro
authors.initials: S
authors.lastname: Amano
mesh_terms: D000528:Alternaria / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000008:administration & dosage*; D003315:Cornea / Q000382:microbiology* / Q000473:pathology; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005901:Glaucoma / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents
references.citation: Curr Opin Ophthalmol. 2004 Aug;15(4):321-7
references.pmid: 15232472
references.citation: Cornea. 2002 Aug;21(6):555-9
references.pmid: 12131029
references.citation: J Glaucoma. 2003 Dec;12(6):480-5
references.pmid: 14646683
references.citation: CLAO J. 2002 Jul;28(3):149-50
references.pmid: 12144235
references.citation: Am J Dermatopathol. 1996 Dec;18(6):611-3
references.pmid: 8989935
references.citation: CLAO J. 2001 Apr;27(2):111-2
references.pmid: 11352448
references.citation: Mycoses. 2002 Dec;45(11-12):512-4
references.pmid: 12472731
references.citation: Am J Ophthalmol. 1975 May;79(5):881-2
references.pmid: 1170761