title: Unusual presentation of ovarian cellular fibroma coexisting with nodular sclerosing Hodgkin's disease: a case report and review of the literature.
abstract: A case of a nonfunctioning, noncalcified ovarian cellular fibroma in a 15-year-old adolescent girl is described. The fibroma was found incidentally in a patient who was later found to have nodular sclerosing Hodgkin's disease. The patient presented with symptoms suggestive of lymphoma but on exam was found to have a mobile and nontender abdominal mass. Laparotomy exposed a smooth, well-circumscribed left ovarian mass. A left salpingoophorectomy was performed. The mass weighed 2390 g and measured 19 x 15 x 8.5 cm. Approximately 15% of the tumor was composed of large cellular nodules identified as spindle cells having a storiform pattern. Mild nuclear atypia with 2 mitosis per 10 high-power fields was noted. An ovarian fibroma in a 15-year-old is an unexpected diagnosis. Less than 1% of ovarian stromal tumors are found in patients 19 years and younger. The uncommon histology and additional classification as a cellular fibroma as well as the simultaneous diagnosis of 2 neoplasms in this case are remarkable.
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA; Children's Healthcare of Atlanta, Atlanta, GA, USA.
authors.forename: Carrie L
authors.initials: CL
authors.lastname: Stallings
authors.forename: Bahig M
authors.initials: BM
authors.lastname: Shehata
authors.forename: Jenny
authors.initials: J
authors.lastname: Wang
authors.forename: Tiffany S
authors.initials: TS
authors.lastname: Chang
authors.forename: Richard R
authors.initials: RR
authors.lastname: Ricketts
mesh_terms: D000293:Adolescent; D005260:Female; D005350:Fibroma / Q000175:diagnosis*; D006689:Hodgkin Disease / Q000175:diagnosis*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000175:diagnosis*