title: Superficial angiomyxoma with trichofolliculoma.
abstract: We report a case of a superficial angiomyxoma with a trichofolliculoma, found on the trunk of a 51-year-old man. The tumor, measuring 4 cm in maximum diameter and located in the reticular dermis and subcutaneous tissue, was composed of a conglomerate of multiple myxomatous nodules with mucinous stroma and stellate cells. Thin-walled blood vessels were prominent. The histologic examination also revealed abortive hair follicles radiating from the wall of a keratin-filled cyst. Immunohistologically, the stromal cells were positive for vimentin but negative for S-100, smooth muscle a-actin, and desmin. With these findings, the diagnosis of superficial angiomyxoma with trichofolliculoma was made.
authors.affiliation: Department of Dermatology, Hospital Clínico San Carlos, Madrid 28040, Spain. berta.perez@wanadoo.es
authors.forename: Berta
authors.initials: B
authors.lastname: Pérez Tato
authors.forename: Asunción Cuenca
authors.initials: AC
authors.lastname: Sáez
authors.forename: Pedro Ruiz
authors.initials: PR
authors.lastname: Fernández
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D006201:Hair Diseases / Q000378:metabolism / Q000473:pathology*; D018859:Hair Follicle / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000378:metabolism / Q000473:pathology*; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D014746:Vimentin