Primary cutaneous B-cell lymphoma in a child.
Primary cutaneous B-cell lymphoma is a B-cell lymphoma of the skin with no evidence of extracutaneous involvement at the time of diagnosis. In this report, we describe an 8-year-old boy who presented with a firm, alopecic, skin-colored, smooth nodule over the right frontal scalp. Histological examination revealed a mid-to deep-dermal mononuclear lesion. Immunohistochemical staining revealed a B-cell population that was CD10(+), CD5(-), CD21(+), and bcl2(-). This pattern of reactivity is characteristic of primary cutaneous B-cell lymphoma of follicle-center subtype. To the best of our knowledge, this is the first report of this type of cutaneous lymphoma in a child.
Condarco
Tania
T
College of Medicine, University of South Florida, Tampa, Florida, USA.
Sagatys
Elizabeth
E
Prakash
Amy V
AV
Rezania
Dorna
D
Cualing
Hernani
H
D018941:Antigens, CD19 / Q000235:genetics; D018951:Antigens, CD20 / Q000235:genetics; D002648:Child; D005500:Follow-Up Studies; D015326:Gene Rearrangement, B-Lymphocyte, Heavy Chain / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000235:genetics; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D008297:Male; D015260:Neprilysin / Q000235:genetics; D017464:Receptors, Complement 3d / Q000235:genetics; D012535:Scalp / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
D018941:Antigens, CD19; D018951:Antigens, CD20; D005819:Genetic Markers; D007145:Immunoglobulin kappa-Chains; D017464:Receptors, Complement 3d; D015260:Neprilysin