title: Recent approaches for the treatment of periodontitis.
abstract: Periodontal disease is a localised inflammatory response caused by the infection of a periodontal pocket arising from the accumulation of subgingival plaque. Periodontal disease has been considered as a possible risk factor for other systemic diseases such as cardiovascular diseases and pre-term low birth weight infants. Advances in understanding the aetiology, epidemiology and microbiology of periodontal pocket flora have revolutionised the therapeutic strategies for the management of periodontal disease progression. This review summarises the recent developments in the field of intra-pocket drug delivery systems and identifies areas where further research may lead to a clinically effective intra-pocket delivery system.
authors.affiliation: Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: Nilu
authors.initials: N
authors.lastname: Jain
authors.forename: Gaurav K
authors.initials: GK
authors.lastname: Jain
authors.forename: Shamama
authors.initials: S
authors.lastname: Javed
authors.forename: Zeenat
authors.initials: Z
authors.lastname: Iqbal
authors.forename: Sushama
authors.initials: S
authors.lastname: Talegaonkar
authors.forename: Farhan J
authors.initials: FJ
authors.lastname: Ahmad
authors.forename: Roop K
authors.initials: RK
authors.lastname: Khar
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D010518:Periodontitis / Q000188:drug therapy* / Q000473:pathology