Comparison of health-related quality of life measures for chronic renal failure: quality of well-being scale, short-form-6D, and the kidney disease quality of life instrument.
BACKGROUND
Studies have found that health-related quality of life (HRQOL) measurements with different conceptual bases yield widely varying results within the same study sample. Using data from a cohort of patients with chronic kidney failure, the purpose of this study was to compare the Quality of Well-Being Scale-Self-Administered (QWB-SA), the Short-Form-6D (SF-6D), and the Kidney Disease Component Summary (KDCS).


METHODS
Baseline data from a multi-site prospective observational study of 322 veterans receiving hemodialysis were analyzed. Descriptive statistics were calculated. Confirmatory factor analysis was conducted to determine how closely the three HRQOL tools reflected the same underlying construct.


RESULTS
Our confirmatory factor analysis offered strong evidence that the subscales of the QWB-SA, SF-6D, and 7-subscale KDCS measured more than one factor in this study sample. In the three-factor model, the SF-6D and 7-subscale KDCS correlated .911 (P < .05), indicating 83% of the variance in the 7-subscale KDCS was correlated with the SF-6D. However, a two-factor model, in which the highly correlated SF-6D and 7-subscale KDCS were combined, fit the data almost as well as the three-factor model.


CONCLUSIONS
The three HRQOL measures addressed different underlying HRQOL constructs in this sample. The QWB-SA was significantly different from the SF-6D and KDCS.
Saban
Karen L
KL
Center for Management of Chronic Complex Care, Edward Hines Jr. VA Hospital, P.O. Box 5000 (151H), Hines, IL, 60141, USA. Karen.Saban@va.gov
Stroupe
Kevin T
KT
Bryant
Fred B
FB
Reda
Domenic J
DJ
Browning
Margaret M
MM
Hynes
Denise M
DM
D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011446:Prospective Studies; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D006435:Renal Dialysis
Gen Hosp Psychiatry. 2006 Jul-Aug;28(4):306-12
16814629
Nephrol Nurs J. 2006 May-Jun;33(3):285-92
16859200
Qual Life Res. 2005 Feb;14(1):207-19
15789955
Headache. 2000 Sep;40(8):662-71
10971663
Hosp Formul. 1993 May;28(5):486-90, 492, 497-8
10125806
BMJ. 2002 Jun 15;324(7351):1417
12065262
Int J Qual Health Care. 1998 Dec;10(6):509-20
9928590
Qual Life Res. 2005 Jun;14(5):1321-32
16047507
Am J Kidney Dis. 2006 Mar;47(3):455-61
16490624
Kidney Int. 2002 Jan;61(1):239-48
11786106
Health Qual Life Outcomes. 2006 Mar 25;4:20
16563170
Psychol Bull. 1990 Mar;107(2):238-46
2320703
Qual Life Res. 1999 Aug;8(5):447-59
10474286
Int J Audiol. 2005 Mar;44(3):157-63
15916116
Annu Rev Public Health. 1994;15:535-59
8054098
Eura Medicophys. 2006 Jun;42(2):113-9
16767062
Am J Kidney Dis. 2004 Nov;44(5 Suppl 2):54-60
15486875
Qual Life Res. 1994 Oct;3(5):329-38
7841967
Kidney Int. 2005 Dec;68(6):2801-8
16316356
Qual Life Res. 2004 Aug;13(6):1153-61
15287281
Value Health. 2004 Sep-Oct;7(5):602-9
15367255
Health Econ. 2004 Sep;13(9):873-84
15362179
Ann Rheum Dis. 2007 Jun;66(6):771-7
17213254
J Nerv Ment Dis. 2006 Nov;194(11):877-9
17102715
Med Decis Making. 1999 Apr-Jun;19(2):141-8
10231076
Health Serv Res. 1988 Jun;23(2):203-35
3384669
Appl Health Econ Health Policy. 2004;3(2):91-102
15702946
J Natl Cancer Inst Monogr. 2004;(33):78-101
15504921
Health Econ. 2003 Nov;12(11):975-81
14601159
Qual Life Res. 2005 May;14(4):971-80
16041894
J Psychosom Res. 2006 Nov;61(5):731-4
17084154
Qual Life Res. 2007 May;16(4):545-57
17286199
Eur J Health Econ. 2005 Sep;6(3):253-60
15968563
Clin Nephrol. 2006 Dec;66(6):440-6
17176916
Acad Emerg Med. 1999 Jan;6(1):54-66
9928978
Arch Phys Med Rehabil. 2006 May;87(5):680-7
16635631
J Clin Epidemiol. 1998 Nov;51(11):1115-28
9817129
Med Care. 1992 Jun;30(6):473-83
1593914
Am J Kidney Dis. 2003 Mar;41(3):605-15
12612984
Neurology. 2002 Jul 9;59(1):103-8
12105315
Clin J Am Soc Nephrol. 2008 Jan;3(1):111-6
18178781
Med Decis Making. 1997 Jan-Mar;17(1):1-9
8994146
J Health Econ. 2002 Mar;21(2):271-92
11939242
Qual Life Res. 2005 Jun;14(5):1333-44
16047508
Health Econ. 2005 Nov;14(11):1169-89
15942981
Int Urol Nephrol. 2004;36(2):263-7
15368708
Med Care. 2004 Sep;42(9):851-9
15319610
Kidney Int. 2005 Mar;67(3):1093-104
15698450
Health Econ. 2003 Dec;12(12):1061-7
14673814
Clin Nephrol. 2003 Nov;60(5):341-51
14640240
Qual Life Res. 2002 Aug;11(5):437-47
12113391
Psychol Bull. 1989 Sep;106(2):315-7
2678203
Pharmacoeconomics. 1998 Apr;13(4):411-20
10178665
Qual Life Res. 2005 Feb;14(1):179-90
15789952
Clin Transplant. 2008 Jul-Aug;22(4):405-10
18363736