Putting ThPOK in place.
ThPOK is necessary for the differentiation of CD4+ helper T cells. Three new studies indicate that, unexpectedly, ThPOK is required only after initial specification to the CD4+ lineage.
Bell
J Jeremiah
JJ
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Bhandoola
Avinash
A
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000166:cytology*; D002454:Cell Differentiation / Q000276:immunology*; D019070:Cell Lineage / Q000276:immunology; D006801:Humans; D014157:Transcription Factors / Q000276:immunology*
D014157:Transcription Factors; C497211:Zbtb7b protein, mouse