title: Iloprost treatment for refractory Raynaud's phenomenon in two infants.
abstract: Raynaud's phenomenon (RP) is rare in young children. We describe two infants with severe RP, manifesting as fingertip necrosis, who were resistant to conventional vasodilators and were treated successfully with iloprost, a prostacyclin analogue. The application of iloprost is safe and should be considered in children with threatening ischemic digits.
authors.affiliation: Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. dror_sho@netvision.net.il
authors.forename: D S
authors.initials: DS
authors.lastname: Shouval
authors.forename: M
authors.initials: M
authors.lastname: Mukamel
authors.forename: F
authors.initials: F
authors.lastname: Zulian
authors.forename: J
authors.initials: J
authors.lastname: Amir
authors.forename: L
authors.initials: L
authors.lastname: Harel
mesh_terms: D005260:Female; D005385:Fingers / Q000098:blood supply / Q000473:pathology; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D009336:Necrosis; D011928:Raynaud Disease / Q000188:drug therapy* / Q000473:pathology; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D016285:Iloprost