title: [A case of advanced gastric cancer successfully treated by surgery after chemotherapy with S-1/CDDP].
abstract: A-46-year-old male with advanced-stage IV multicentric gastric cancer was treated with S-1/CDDP as neoadjuvant chemotherapy. S-1 (initially 100 mg/day, up to 120 mg/day) was orally administered for 3 weeks (day 1-21) followed by 1 drug-free week as a course, and CDDP (initially 60 mg/day, up to 100 mg/day) was administered by intravenous drip on day 8. After the fourth course, a significant tumor reduction was obtained and curative surgery was performed. Thereafter, S-1 therapy was continued. There has not been any recurrence for 19 months postoperatively.
authors.affiliation: Dept. of Gastroenterology, Suwa Red Cross Hospital.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Shinji
authors.forename: Kenji
authors.initials: K
authors.lastname: Mukawa
authors.forename: Taro
authors.initials: T
authors.lastname: Mochizuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohta
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hara
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Yamamura
authors.forename: Hisao
authors.initials: H
authors.lastname: Oguchi
authors.forename: Kou
authors.initials: K
authors.lastname: Shimada
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Yazawa
authors.forename: Shoji
authors.initials: S
authors.lastname: Kajikawa
authors.forename: Toshitsugu
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000627:therapeutic use*; D004338:Drug Combinations; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin