title: Algicidal activity of stilbene analogues.
abstract: Continuing our search for natural product and natural product-based compounds for the control of off-flavor in catfish, 29 stilbene analogues were synthesized and evaluated for algicidal activity against the 2-methylisoborneol (MIB)-producing cyanobacterium Oscillatoria perornata. The cis and trans isomers of 4-(3,5-dimethoxystyryl)aniline showed moderate and selective algicidal activity toward O. perornata with the lowest observed inhibitory concentration and lowest complete inhibition concentrations of 10 muM. This is the first report on selective stilbene algicidal activity toward a MIB-producing cyanobacteria species.
authors.affiliation: Natural Products Utilization Research Unit, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 8048, University, Mississippi 38677-8048, USA.
authors.forename: Cassia S
authors.initials: CS
authors.lastname: Mizuno
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Schrader
authors.forename: Agnes M
authors.initials: AM
authors.lastname: Rimando
mesh_terms: D000818:Animals; D001892:Camphanes / Q000378:metabolism; D007059:Ictaluridae; D054300:Oscillatoria / Q000187:drug effects* / Q000378:metabolism; D013267:Stilbenes / Q000138:chemical synthesis / Q000494:pharmacology*; D013649:Taste
chemical_list: D001892:Camphanes; D013267:Stilbenes; C005536:2-methylisoborneol