title: MRI in paediatric hypoxic-ischemic disease, metabolic disorders and malformations-a review.
abstract: MRI has become the most important modality in paediatric neuroimaging. It provides an excellent anatomical overview with good spatial and temporal resolution, allows investigations of the blood vessels, and - using technologies such as diffusion-weighted imaging and magnetic resonance spectroscopy - it allows quick and exact differentiation of ischemic, hypoxic, inflammatory, oncologic, traumatic and metabolic diseases. This review presents an overview of brain MRI in infants and children with suspected hypoxic-ischemic disease, metabolic disorders or (vascular) malformations, illustrating these issues by some MRI findings in selected important conditions and discussing some major clinical and pathophysiological aspects important for imaging.
authors.affiliation: Department of Radiology, Division of Neuroradiology, Medical University, Graz, Austria. dietrich.beitzke@meduni-graz.at
authors.forename: Dietrich
authors.initials: D
authors.lastname: Beitzke
authors.forename: Josef
authors.initials: J
authors.lastname: Simbrunner
authors.forename: Michael
authors.initials: M
authors.lastname: Riccabona
mesh_terms: D001921:Brain / Q000002:abnormalities*; D001928:Brain Diseases, Metabolic / Q000151:congenital / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000151:congenital / Q000175:diagnosis*; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*