title: Finding at-DNA--kinetic recognition of long adenine-thymine stretches by metal-ligand complexes.
abstract: High selectivity for long AT sequences can be attained by kinetically controlled DNA threading intercalation by binuclear ruthenium(II) complexes. The rate of intercalation is strongly correlated to the number of consecutive AT basepairs, being up to 2500 times faster with an AT polymer compared to mixed-sequence DNA.
authors.affiliation: Department of Chemical and Biological Engineering/Physical Chemistry, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden. par.nordell@chalmers.se
authors.forename: Pär
authors.initials: P
authors.lastname: Nordell
authors.forename: Fredrik
authors.initials: F
authors.lastname: Westerlund
authors.forename: Anna
authors.initials: A
authors.lastname: Reymer
authors.forename: Bengt
authors.initials: B
authors.lastname: Nordén
authors.forename: Per
authors.initials: P
authors.lastname: Lincoln
mesh_terms: D004247:DNA / Q000737:chemistry*; D007700:Kinetics; D008024:Ligands; D008163:Luminescent Measurements; D009942:Organometallic Compounds / Q000737:chemistry*; D011067:Poly dA-dT / Q000737:chemistry*
chemical_list: D008024:Ligands; D009942:Organometallic Compounds; D011067:Poly dA-dT; D004247:DNA