Artificial beta-sheets: chemical models of beta-sheets.
Chemical models provide tools with which to simplify and study complicated biological systems. Forces and chemical processes that govern the structure, function, and interactions of a biomacromolecule can be explored with a simple, easy-to-study synthetic molecule. Chemical models of beta-sheet structures have helped to elucidate the factors influencing protein structures and functions. Chemical models that mimic beta-sheet quaternary structure and interactions are emerging as valuable tools with which to better understand and control protein recognition and protein aggregation.
Khakshoor
Omid
O
Department of Chemistry, University of California, Irvine, Irvine, CA 92697-2025, USA.
Nowick
James S
JS
D040761:Biomimetic Materials / Q000737:chemistry; D006801:Humans; D008956:Models, Chemical; D010456:Peptides, Cyclic / Q000737:chemistry; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
D010456:Peptides, Cyclic; D011506:Proteins
J Mol Biol. 2006 Feb 10;356(1):32-44
16337654
Chem Rev. 2004 Dec;104(12):6085-117
15584696
Org Biomol Chem. 2006 May 21;4(10):1896-901
16688335
J Am Chem Soc. 2001 Jan 17;123(2):343-4
11456526
Angew Chem Int Ed Engl. 2001 Mar 16;40(6):988-1011
11268062
Chem Commun (Camb). 2006 Aug 7;(29):3069-71
16855688
Chemistry. 2005 Dec 23;12(2):403-12
16187380
Chem Commun (Camb). 2008 Feb 21;(7):844-6
18253523
J Am Chem Soc. 2007 May 2;129(17):5558-69
17419629
Org Biomol Chem. 2006 Nov 7;4(21):3869-85
17047863
Biopolymers. 2007;88(5):746-53
17427180
Nat Mater. 2007 Aug;6(8):576-80
17558430
Angew Chem Int Ed Engl. 2005 Sep 5;44(35):5710-3
16080230
Angew Chem Int Ed Engl. 2002 Oct 18;41(20):3863-5
12386872
Biopolymers. 2007;88(3):350-61
17154289
Biomacromolecules. 2006 Aug;7(8):2394-400
16903687
Chemistry. 2008;14(7):2100-11
18165949
J Am Chem Soc. 2005 Mar 9;127(9):2929-36
15740129
Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8747-51
8090717
Curr Opin Chem Biol. 1998 Dec;2(6):717-25
9914187
Chemistry. 2008;14(15):4488-502
18449870
J Am Chem Soc. 2007 Oct 31;129(43):13043-8
17918935
J Am Chem Soc. 2006 Jun 7;128(22):7148-9
16734453
J Org Chem. 2008 Jan 18;73(2):652-60
18076186
Chemistry. 2006 Jan 23;12(4):1114-20
16294349
Acc Chem Res. 2008 Oct;41(10):1354-65
18590283
J Am Chem Soc. 2008 Jun 25;130(25):7839-41
18507461
Biopolymers. 2007;88(2):150-6
17260351
Curr Opin Struct Biol. 2004 Aug;14(4):458-64
15313241
Chemistry. 2008;14(2):488-99
17943702
Chem Rev. 2001 Oct;101(10):3131-52
11710065
Acc Chem Res. 2008 Oct;41(10):1319-30
18798654
Chem Commun (Camb). 2007 Aug 21;(31):3267-9
17668096
Trends Biochem Sci. 2006 Aug;31(8):436-44
16828554
Curr Opin Struct Biol. 2006 Aug;16(4):514-24
16837192
J Am Chem Soc. 2007 Feb 14;129(6):1653-7
17243683
Chem Soc Rev. 2006 Dec;35(12):1269-86
17225888
Org Lett. 2007 Dec 20;9(26):5457-60
18031052
Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12183-8
15302930
Acc Chem Res. 2008 Oct;41(10):1278-88
18412373
Chemistry. 2007;13(20):5917-26
17393543
J Am Chem Soc. 2007 Mar 7;129(9):2548-58
17295482
Protein Sci. 1998 Feb;7(2):358-68
9521112
Chem Soc Rev. 2004 Jun 20;33(5):294-301
15272369
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15729-34
17893334
Chem Commun (Camb). 2006 Dec 14;(46):4847-9
17345749
Protein Sci. 2002 Jun;11(6):1539-51
12021452