title: Acute colitis associated with dengue fever in a renal transplant recipient.
abstract: Dengue fever is a significant health problem for international travelers to all endemic area. Dengue fever is characterized by a sudden onset of fever, headache, rash, myalgia, and joint pain. Infection with the dengue virus is detrimental to a immunosuppressed renal transplant patients. Herein we report a 29-year-old woman living-related renal transplant recipient returning from Southeast Asia with dengue fever presenting as acute colitis. The patient traveled to Southeast Asia for 1 week. She developed watery diarrhea in the second week after the onset of symptoms of dengue fever. Laboratory findings were leukopenia, thrombocytopenia, and elevated serum transaminase levels. Sigmoidoscopic features showed nonspecific acute colitis. She improved after 10 days of hospitalization with intensive supportive care and continuous tacrolimus monotherapy. Altered clinical symptoms are manifested in immunologically naïve adults. Manifestation of unusual symptoms does not exclude dengue virus infection in renal transplant recipients.
authors.affiliation: Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institute, Daegu, Korea. sbpark@dsmc.or.kr
authors.forename: S B
authors.initials: SB
authors.lastname: Park
authors.forename: S Y
authors.initials: SY
authors.lastname: Ryu
authors.forename: K B
authors.initials: KB
authors.lastname: Jin
authors.forename: E A
authors.initials: EA
authors.lastname: Hwang
authors.forename: S Y
authors.initials: SY
authors.lastname: Han
authors.forename: H T
authors.initials: HT
authors.lastname: Kim
authors.forename: W H
authors.initials: WH
authors.lastname: Cho
authors.forename: J H
authors.initials: JH
authors.lastname: Kwak
authors.forename: K S
authors.initials: KS
authors.lastname: Ahn
authors.forename: H C
authors.initials: HC
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D000328:Adult; D003092:Colitis / Q000209:etiology*; D003715:Dengue / Q000150:complications*; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications / Q000821:virology; D014195:Travel