[Systematic continuous sequence approach in diagnosing fetal deformity].
OBJECTIVE
To explore the value of ultrasonographic evaluation in fetal deformity in prenatal diagnosis by a systematic continuous sequence approach (SCSA).


METHODS
Successive prenatal ultrasonographic evaluation was performed to monitor the whole anatomic structure,form, posture and movement of 16,685 fetuses during gestation aging 14 approximately 40(+3) weeks.


RESULTS
Satisfactory ultrasonic images were obtained in 16,627 fetuses using the SCSA (99.65%). Of them, 514 abnormal fetuses were confirmed after subsequent labor or induced labor and 498 abnormal fetuses were correctly diagnosed using SCSA during prenatal stage (96.89%). Whereas 16 fetuses missed recognition (3.11%). Its sensitivity, specificity, positive and negative predictive value of diagnosis on fetal deformity were 96.98%, 99.96%, 98.66%, and 99.90 %, respectively.


CONCLUSIONS
SCSA in prenatal ultrasonographic evaluation of the fetal structure and malformation is reliable and accurate.
Chen
Qi-neng
QN
Department of Gynecology and Obstetrics, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhang
Wei-she
WS
Tan
Jin-xiu
JX
Lu
Rong
R
Wu
Xin-hua
XH
D000328:Adult; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods