title: Familial dysbetalipoproteinemia: a potentially fatal disorder.
abstract: Familial dysbetalipoproteinemia is an inherited disorder in which both cholesterol and triglycerides are elevated in the plasma of the blood, which pre-disposes people to coronary artery disease and peripheral vascular disease. We report two young boys with multiple cutaneous xanthomas and grossly abnormal serum cholesterol and triglycerides. Two of the family members had died of cardiovascular accidents in young age and rest of the family members had deranged lipid profile. Patients were managed with lipid lowering drugs and fat restriction diet. All family members were counseled and advised regular exercise and follow-up.
authors.affiliation: Department of Dermatology, Combined Military Hospital, Peshawar, Pakistan. albariul@gmail.com
authors.forename: Arfan Ul
authors.initials: AU
authors.lastname: Bari
authors.forename: Rizwan
authors.initials: R
authors.lastname: Hashim
authors.forename: Simeen Ber
authors.initials: SB
authors.lastname: Rahman
authors.forename: Majid
authors.initials: M
authors.lastname: Hussain
mesh_terms: D000293:Adolescent; D000328:Adult; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D000069059:Atorvastatin; D015248:Gemfibrozil / Q000627:therapeutic use; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D006952:Hyperlipoproteinemia Type III / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008297:Male; D011758:Pyrroles / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D000924:Anticholesteremic Agents; D006538:Heptanoic Acids; D000960:Hypolipidemic Agents; D011758:Pyrroles; D000069059:Atorvastatin; D015248:Gemfibrozil