Use of urine albumin/creatinine ratio for estimation of proteinuria in cats and dogs.
The clinical utility of the urine albumin/creatinine ratio (UAC) using a simplified analyzer for estimation of proteinuria was studied in cats and dogs. Measurement results for diluted feline and canine albumin standard solutions showed linearity. Although conversion formulas (y=1.28x+1.04 and y=1.67x+10.47 for cats and dogs, respectively) were necessary, urine albumin concentrations could be determined in both animals. In cats and dogs with proteinuria, the UAC changed parallel with the urine protein/ creatinine ratio (UPC), and the Log UAC and Log UPC were significantly correlated (r=0.803 (p<0.01) in cats, r=0.801 (p<0.01) in dogs). The UAC using an UAC analyzer could be used clinically as one of the basic in-hospital laboratory tests for estimation of proteinuria in cats and dogs.
Kuwahar
Yasuhito
Y
Kuwahara Animal Hospital, Moriyama-ku, nagoya, Japan.
Nishii
Naohito
N
Takasu
Masaki
M
Ohba
Yasunori
Y
Maeda
Sadatoshi
S
Kitagawa
Hitoshi
H
D000419:Albuminuria / Q000378:metabolism / Q000662:veterinary; D000818:Animals; D002371:Cat Diseases / Q000652:urine*; D002415:Cats; D003404:Creatinine / Q000652:urine*; D004283:Dog Diseases / Q000652:urine*; D004285:Dogs; D007676:Kidney Failure, Chronic / Q000652:urine / Q000662:veterinary*; D011507:Proteinuria / Q000378:metabolism / Q000662:veterinary*
D003404:Creatinine