[Adiponectin levels in perimenopause].
BACKGROUND
Adiponectin is an hormone produced exclusively in adipose tissue, that actively acts in carbohydrate and fat regulation processes.


OBJECTIVE
To determine adiponectin levels in a women's group.


METHODS
Transversal study in 22 amenorrheal women with climacteric symptoms, and without estrogen therapy. There were excluded those with diabetes, hypertension, dislipoproteinemia and obesity. Significant differences among values of adiponectin in perimenopausal and young women during follicular phase of menstrual cycle were analyzed by means of Student t test.


RESULTS
Adiponectin concentration in perimenopausal women was 14.1 +/- 8.2 microg/mL (M +/- SD), without meaningful difference compared with young women.


CONCLUSIONS
It wasn't significant variation in adiponectin levels compared with normal menstrual cycle women. Further studies are necessary to establish adiponectin effect in postmenopause and its relation with the cardiovascular diseases.
Valencia
Marcelino Hernández
MH
Unidad de Investigación en Enfermedades Endocrinas, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social y Hospital Angeles México, México, DF.
Zárate
Arturo
A
Galván
Rosa Elba
RE
D052242:Adiponectin / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D047648:Perimenopause / Q000097:blood*
D052242:Adiponectin