Agnathia and associated malformations in a male rhesus monkey.
BACKGROUND
Agnathia is a rare malformation characterized by the absence of the mandible.


METHODS
A male rhesus monkey with malformations was found dead and studied by internal examination, radiographs and histopathology.


RESULTS
A case of a rare first branchial arch anomaly with agenesis of the mandible and tongue is presented. The animal also had visceral deformities. However, ears were normal in shape and only slightly low in position. The craniofacial malformations may reflect incomplete separation of the first branchial arch into its maxillary and mandibular processes.


CONCLUSIONS
The association between the craniofacial and other corporal anomalies is unclear.
Goldschmidt
B
B
Oswaldo Cruz Foundation, Center for Laboratory Animal Breeding, Department of Primatology, Av. Brasil, 4365 Manguinhos, Brazil. bibi@fiocruz.br
Lopes
C A
CA
Moura
M
M
Fasano
D M
DM
Andrade
M C R
MC
Cysne
L B
LB
Gonçalves
M B
MB
Bravin
J S
JS
Kugelmeier
T
T
Viana
C F
CF
Silva
F A
FA
Marinho
A M
AM
D000818:Animals; D000831:Animals, Newborn; D019465:Craniofacial Abnormalities / Q000662:veterinary*; D004065:Digestive System Abnormalities / Q000662:veterinary; D005260:Female; D008253:Macaca mulatta / Q000002:abnormalities*; D008297:Male; D008334:Mandible / Q000002:abnormalities*; D014059:Tongue / Q000002:abnormalities*