Assessment of biochemical markers of carbofuran toxicity and recovery response in tissues of the freshwater teleost, Clarias batrachus (Linn).
The effects of a sublethal concentration (7.66 mg/L) of carbofuran, were assessed on Clarias batrachus. The fish were exposed to 7.66 mg of carbofuran/L for 6 days. After 6 days, fish were released into carbofuran-free water in order to study the recovery pattern. Proteins were decreased in gill and kidney and recovery was greater in gill than in kidney. Total amino acids were increased in both tissues. Ammonia level declined in gill and enhanced in kidney throughout the study period. The activities of all enzymes measured were induced in both tissues, except for aspartate aminotransaminase, which was inhibited in gill tissues.
Begum
Ghousia
G
Fisheries Lab, Department of Zoology, College of Science, Osmania University, Hyderabad, 500 007 AP, India. Ghousia786@yahoo.com
D000410:Alanine Transaminase / Q000097:blood; D000596:Amino Acids / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000037:antagonists & inhibitors / Q000097:blood; D015415:Biomarkers / Q000032:analysis*; D002235:Carbofuran / Q000633:toxicity*; D004790:Enzyme Induction / Q000187:drug effects; D005399:Fishes / Q000502:physiology*; D005880:Gills / Q000473:pathology; D005969:Glutamate Dehydrogenase / Q000097:blood; D007306:Insecticides / Q000633:toxicity*; D007668:Kidney / Q000473:pathology; D011506:Proteins / Q000378:metabolism
D000596:Amino Acids; D015415:Biomarkers; D007306:Insecticides; D011506:Proteins; D000641:Ammonia; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D002235:Carbofuran