Acute hemorrhagic edema of infancy: report of 4 cases and review of the current literature.
Acute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclastic vasculitis that usually occurs in children younger than 2 years of age. It is a rare disease characterized by mild fever, a violent onset of hemorrhagic skin lesions, and edema usually followed by a spontaneous and complete recovery. Although the etiology is unknown, AHEI often follows infections, drug treatment, or vaccination. In the present report, the authors describe 4 cases of AHEI and review the relevant literature.
Karremann
Michael
M
Department of Pediatrics, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. michael.karremann@kikli.ma.uni-heidelberg.de
Jordan
Alexander J
AJ
Bell
Nellie
N
Witsch
Michael
M
Dürken
Matthias
M
D000208:Acute Disease; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D004487:Edema / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*
D018712:Analgesics, Non-Narcotic; D000900:Anti-Bacterial Agents