Hypogonadotropic hypogonadism: a consequence of Chiari-I malformation.
Chronic hydrocephalus, most commonly the result of aqueduct stenosis, is associated with both primary and secondary amenorrhea. Only six cases of secondary amenorrhea have been reported to date. We describe a women with cystic fibrosis who presented with secondary amenorrhea as a consequence of Chiari-I malformation and resultant hydrocephalus. The biochemical picture was characterized by hypogonadotropic hypogonadism. Resolution of the amenorrhea was observed to occur following 3rd ventriculostomy.
Kumar
Sampath Satish
SS
Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, D Floor, Brotherton Wing, Leeds General Infirmary, Great George Street, Leeds, UK.
Chumas
Paul
P
Peckham
Daniel
D
Guthrie
Ashley
A
Murray
Robert D
RD
D000568:Amenorrhea / Q000473:pathology / Q000601:surgery; D001139:Arnold-Chiari Malformation / Q000150:complications*; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014696:Ventriculostomy; D055815:Young Adult
Eur J Endocrinol. 1998 Feb;138(2):170-5
9506861
Pediatr Dev Pathol. 2003 Jan-Feb;6(1):88-93
12415481
Pediatr Pulmonol. 2000 Dec;30(6):490-2
11109062
Eur J Pediatr. 1997 Aug;156(8):597-601
9266188
J Neurosurg. 1996 Dec;85(6):1148-52
8929509
Childs Nerv Syst. 1995 Mar;11(3):180-5
7773981
Fertil Steril. 2001 Aug;76(2):390-3
11476794
J Korean Med Sci. 2001 Aug;16(4):532-6
11511805