Greener biocatalytic approach to the synthesis of nucleosides and their precursors.
Novel, efficient and selective biocatalytic acylation / deacylation strategies have been used for the greener synthesis of precursors of different bicyclonucleosides. Biocatalytic methodology has also been developed for the separation of pyrano- and furanonucleosides, which is otherwise almost impossible to achieve by usual chemical approach.
Singh
Sunil K
SK
Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110 007, India.
Sharma
Raman K
RK
Maity
Jyotirmoy
J
Wengel
Jesper
J
Parmar
Virinder S
VS
Prasad
Ashok K
AK
D000215:Acylation; D002384:Catalysis; D005663:Furans / Q000737:chemistry; D055772:Green Chemistry Technology; D008049:Lipase / Q000378:metabolism; D009705:Nucleosides / Q000096:biosynthesis* / Q000737:chemistry; D011714:Pyrans / Q000737:chemistry
D005663:Furans; D009705:Nucleosides; D011714:Pyrans; D008049:Lipase