The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Multiple mechanisms limit exercise in COPD.
Calverley
Peter M
PM
University of Liverpool, Liverpool, UK.
D017079:Exercise Tolerance / Q000502:physiology*; D006801:Humans; D035002:Lower Extremity / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000503:physiopathology; D010101:Oxygen Consumption / Q000502:physiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D015656:Respiratory Mechanics / Q000502:physiology*