title: Lemierre syndrome in a 5-month-old male infant: Case report and review of the pediatric literature.
abstract: OBJECTIVE
  To report, to the best of our knowledge, the youngest patient with Lemierre syndrome.
  
  
  METHODS
  Descriptive case report with review of the pediatric literature.
  
  
  METHODS
  Pediatric intensive care unit in a tertiary referral hospital.
  
  
  METHODS
  Systemic review of the literature, including PubMed (English-only journals) and major textbooks.
  
  
  METHODS
  We report a 5-month-old boy who presented with fever and a perforated left-sided otitis media. He developed left-sided complicated otitis media with retroauricular fluid collection, mastoiditis, and temporomandibular joint effusion. The clinical picture was complicated by a left internal jugular vein and left lateral sinus thrombosis. Fusobacterium necrophorum grew in the pus culture.
  
  
  METHODS
  Low molecular weight heparin.
  
  
  RESULTS
  No immunodeficiency and no thrombophilia were identified as predisposing conditions for Lemierre syndrome. Surgical drainage, early and adequate antibiotic treatment, and anticoagulation were followed by complete recovery.
  
  
  CONCLUSIONS
  This case report illustrates that Lemierre syndrome can occur in infants without underlying risk factors for severe infections or thrombotic complications.
authors.affiliation: Divisions of Neonatal and Pediatric Intensive Care Unit (FA), Pediatric Radiology (JPVN), Otorhinolaryngology, Head and Neck Surgery (EP), and Pediatrics (FB), Clinique Pédiatrique, Centre Hospitalier de Luxembourg, Luxembourg, USA. faspes@hotmail.com
authors.forename: François
authors.initials: F
authors.lastname: Aspesberro
authors.forename: Thomas
authors.initials: T
authors.lastname: Siebler
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Van Nieuwenhuyse
authors.forename: Eugène
authors.initials: E
authors.lastname: Panosetti
authors.forename: Françoise
authors.initials: F
authors.lastname: Berthet
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D005673:Fusobacterium / Q000302:isolation & purification*; D005674:Fusobacterium Infections / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007601:Jugular Veins / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010033:Otitis Media / Q000150:complications*; D018805:Sepsis / Q000209:etiology; D013577:Syndrome; D013924:Thrombophlebitis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight