Pyrrolidine analogues of nucleosides and nucleotides.
Among the structurally diverse nucleoside phosphonic acids, several compounds possessing strong antiviral properties have been found. Our effort in this area was focused to the synthesis of novel compounds - pyrrolidine-based nucleoside phosphonic acids and their derivatives.
Rejman
Dominik
D
Institute of Organic Chemistry and Biochemistry, Flemingovo n. 2, Prague 6, Czech Republic. rejman@uochb.cas.cz
Pohl
Radek
R
Kovacková
Sona
S
Kocalka
Petr
P
Svenková
Alzbĕta
A
Sanderová
Hana
H
Krásný
Libor
L
Rosenberg
Ivan
I
D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D009711:Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D063065:Organophosphonates / Q000737:chemistry; D011759:Pyrrolidines / Q000737:chemistry*
D000998:Antiviral Agents; D009705:Nucleosides; D009711:Nucleotides; D063065:Organophosphonates; D011759:Pyrrolidines