Rifampicin, ethambutol and pyrazinamide-induced thrombocytopenia.
Drug-induced thrombocytopenia is an uncommon but serious side effect of many drugs including antituberculosis drugs. It is difficult to diagnose but easy to prevent just by stopping the exposure to the same drug again. In some cases, it can prove fatal if not taken care of urgently. Here, we report a case of thrombocytopenia due to rifampicin, ethambutol and pyrazinamide all in an adult male, which we believe is the first to be reported.
Kant
S
S
Department of Pulmonary Medicine, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.
Natu
N K
NK
Mahajan
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V
D000368:Aged; D000995:Antitubercular Agents / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000009:adverse effects; D006801:Humans; D008297:Male; D011718:Pyrazinamide / Q000009:adverse effects; D012293:Rifampin / Q000009:adverse effects; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis
D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D012293:Rifampin