title: [A case of pulmonary pleomorphic carcinoma with epidermal growth factor receptor (EGFR) mutation].
abstract: A 70-year-old woman with cough was diagnosed with pulmonary adenocarcinoma by bronchoscopic transbronchial biopsy. She was diagnosed cT2N0M0, stage IB clinically, and the tumor was surgically resected. Postoperative pathology was confirmed to be pleomorphic carcinoma of pT2N2M0, stage III A. She received 6 courses of adjuvant chemotherapy consisting of cisplatin and docetaxel. Five months later, new pulmonary and bone metastases were detected. Gefitinib was started, and she has shown stable disease for 7 months. Epidermal growth factor receptor (EGFR) mutation was observed in her tumor specimens.
authors.affiliation: Dept. of Pulmonary Medicine, Fukushima Medical University.
authors.forename: Kana
authors.initials: K
authors.lastname: Watanabe
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishida
authors.forename: Atsuro
authors.initials: A
authors.lastname: Fukuhara
authors.forename: Satoko
authors.initials: S
authors.lastname: Sekine
authors.forename: Kumi
authors.initials: K
authors.lastname: Uekita
authors.forename: Aya
authors.initials: A
authors.lastname: Sugawara
authors.forename: Motoko
authors.initials: M
authors.lastname: Tachihara
authors.forename: Kenya
authors.initials: K
authors.lastname: Kanazawa
authors.forename: Junpei
authors.initials: J
authors.lastname: Saito
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tanino
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Munakata
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D066246:ErbB Receptors / Q000235:genetics*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D009154:Mutation; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D066246:ErbB Receptors