Molecular beacons in biomedical detection and clinical diagnosis.
Among the diverse nucleic acid probes, molecular beacons (MBs) have shown their excellent potential in a variety of basic researches and practical applications. Their excellent selectivity, sensitivity, and detection without separation have led them to be particularly useful in real-time intracellular monitoring of gene expression, development of biosensors, and clinical diagnostics. This paper will focus on the properties of various MBs and discuss their potential applications.
Kim
Youngmi
Y
Center for Research at the Bio/nano Interface, Department of Chemistry and UF Genetics Institute, Shands Cancer Center and McKnight Brain Institute, University of Florida Gainesville, FL, USA.
Sohn
Dosung
D
Tan
Weihong
W
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