title: Synthesis of novel cyclopropyl nucleoside analogues as potential antiherpetic agent.
abstract: Synthesis of novel cyclopropyl pyrimidine and purine nucleoside derivatives was successfully achieved using one pot reactions including an alkylation, an oxirane-ring opening reaction and a lactonization and a hydroboration-oxidation as the key steps in order to find new antiherpetic agent.
authors.affiliation: College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 609-735, Korea.
authors.forename: Jin-Ah
authors.initials: JA
authors.lastname: Kang
authors.forename: Ah-Young
authors.initials: AY
authors.lastname: Park
authors.forename: Hyung-Rock
authors.initials: HR
authors.lastname: Lee
authors.forename: Won Hee
authors.initials: WH
authors.lastname: Kim
authors.forename: Pusoon
authors.initials: P
authors.lastname: Chun
authors.forename: Lak Shin
authors.initials: LS
authors.lastname: Jeong
authors.forename: Hyung Ryong
authors.initials: HR
authors.lastname: Moon
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry; D006564:Herpesviridae / Q000187:drug effects; D013941:Thymine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000998:Antiviral Agents; D000225:Adenine; D013941:Thymine