title: [Therapeutic efficacy and safety of off-label use of Bevacizumab for the treatment of neovascular diseases of the eye].
abstract: Clinical trial of off-label use of Bevacizumab for the treatment of neovascular diseases of the eye showed good therapeutic results. It has been demonstrated that this therapy is efficient and safe in the treatment of choroidal neovascularization due to age-related macular degeneration, pathologic myopia and other neovascular eye diseases in short term period. The potential risks to the patients are minimal, and the cost-effectiveness is so obvious that the treatment strategy using intravitreal bevacizumab is logical and understandable.
authors.affiliation: Department of Ophthalmology, First Affiliated Hospital of Shanghai Jiaotong University, Shanghai 200080, China. xdsun@sjtu.edu.cn
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Sun
authors.forename: Wei-Qi
authors.initials: WQ
authors.lastname: Xu
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenfeld
mesh_terms: D020533:Angiogenesis Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D020256:Choroidal Neovascularization / Q000188:drug therapy*; D006801:Humans; D056687:Off-Label Use
chemical_list: D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab