title: Eye movement involvement in Parry-Romberg Syndrome: a clinicopathologic case report.
abstract: We report the case of a 38-year-old woman who developed a progressive bilateral disease in which the eye motility disorder-diplopia-is the outstanding feature over a period of 12 years. The muscle biopsy of the medial rectus muscle did not show any trace of striated muscle. To the best of our knowledge, this is the first pathological report in an affected extraocular muscle of a patient with Parry-Romberg syndrome (PRS). Previous rare reports of diplopia in PRS have been attributed to enophthalmos, progressive atrophy of the orbit, ocular motor nerve dysfunction, or mechanical restrictions.
authors.affiliation: University Eye Hospital, Johann-Wolfgang-Goethe-Universitat Frankfurt/Main, Frankfurt, Germany. zubcov@argus-augen-op.de
authors.forename: A A
authors.initials: AA
authors.lastname: Zubcov-Iwantscheff
authors.forename: F
authors.initials: F
authors.lastname: Thomke
authors.forename: H H
authors.initials: HH
authors.lastname: Goebel
authors.forename: M
authors.initials: M
authors.lastname: Bacharach-Buhles
authors.forename: A
authors.initials: A
authors.lastname: Cordey
authors.forename: C S
authors.initials: CS
authors.lastname: Constantinescu
authors.forename: I
authors.initials: I
authors.lastname: Gottlob
mesh_terms: D000328:Adult; D004172:Diplopia / Q000209:etiology; D005133:Eye Movements; D005150:Facial Hemiatrophy / Q000150:complications / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D005355:Fibrosis; D006801:Humans; D015835:Ocular Motility Disorders / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000473:pathology* / Q000503:physiopathology*