title: A new chromone glycoside from Rhododendron spinuliferum.
abstract: A new chromone glycoside, 3,5,7-trihydroxylchromone-3-O-alpha-L-arabinopyranoside (1), together with quercetin (2), (+)-catechin (3), (-)-epi-catechin (4) were isolated from the aerial parts of Rhododendron spinuliferum. The structure of 1 was elucidated on the basis of spectroscopic and 2D-NMR spectral analysis. In addition, 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.
authors.affiliation: School of Pharmacy, Shanghai Jiaotong University, Shanghai, 200240, PR China.
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Hui Zi
authors.initials: HZ
authors.lastname: Jin
authors.forename: Xue Feng
authors.initials: XF
authors.lastname: Li
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.forename: Yun Heng
authors.initials: YH
authors.lastname: Shen
authors.forename: Shi Kai
authors.initials: SK
authors.lastname: Yan
authors.forename: Wei Dong
authors.initials: WD
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001089:Arabinose / Q000031:analogs & derivatives* / Q000737:chemistry; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification; D002855:Chromatography, Thin Layer; D002867:Chromones / Q000737:chemistry*; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D009569:Nitric Oxide / Q000096:biosynthesis; D010936:Plant Extracts / Q000737:chemistry; D011794:Quercetin / Q000737:chemistry / Q000302:isolation & purification; D029793:Rhododendron / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: C532260:3,5,7-trihydroxychromone-3-O-arabinopyranoside; D002867:Chromones; D010936:Plant Extracts; D009569:Nitric Oxide; D002392:Catechin; D011794:Quercetin; D001089:Arabinose