title: [Effect of NaFeEDTA on hemoglobin level in iron deficient population: a systematic review].
abstract: OBJECTIVE
  To evaluate the effect of NaFeEDTA on hemoglobin level in iron deficient population.
  
  
  METHODS
  Comprehensive literature retrieval was performed via searching electronic databases, hand searching bibliographies of books and relevant journals, collecting grey literatures, looking into conference abstracts, contacting fields experts and reviewing references and citations. Criteria from Cochrane EPOC review group were used to assess the quality of included studies. Generic inverse variance method was used to undertake meta-analysis.
  
  
  RESULTS
  The pooled estimate for hemoglobin level (weighted mean difference) was 12.14 g/L (95% CI: 5.60-18.69; P < 0.001). Subgroup analysis indicated that lower baseline hemoglobin level and higher dose for intervention were associated to greater increase in hemoglobin level.
  
  
  CONCLUSIONS
  This systematic review indicated that NaFeEDTA improved hemoglobin significantly in iron deficient population.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100083, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.forename: Si-yan
authors.initials: SY
authors.lastname: Zhan
authors.forename: Yin-yin
authors.initials: YY
authors.lastname: Xia
authors.forename: Li-ming
authors.initials: LM
authors.lastname: Li
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000188:drug therapy* / Q000378:metabolism; D004492:Edetic Acid / Q000627:therapeutic use; D005290:Ferric Compounds / Q000627:therapeutic use*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007502:Iron Chelating Agents / Q000627:therapeutic use*
chemical_list: D005290:Ferric Compounds; D006454:Hemoglobins; D007502:Iron Chelating Agents; D004492:Edetic Acid; C019179:Fe(III)-EDTA