title: Multimarker panel in patients admitted to emergency department: a comparison with reference methods.
abstract: OBJECTIVE
  Point of care testing and multimarker panels are rapidly expanding in emergency departments. We determined the reliability of Short-of-Breath SOB panel in patients admitted for acute dyspnea and/or chest pain.
  
  
  METHODS
  SOB D-dimer, BNP, cTnI, CK-MB and myoglobin assays were compared with references in 97 outpatients.
  
  
  RESULTS
  The correlation between SOB and references methods was acceptable, but with limited precision and accuracy.
  
  
  CONCLUSIONS
  Diagnostic performances and cut-off values should be further validated before clinicians replace traditional cardio-respiratory biomarkers by the new SOB panel.
authors.affiliation: Department of Endocrinology and Nutrition, Unit of Diabetes and Nutrition, Cliniques Universitaires St-Luc, Brussels, Belgium. gruson_damien@yahoo.fr
authors.forename: Damien
authors.initials: D
authors.lastname: Gruson
authors.forename: Frédéric
authors.initials: F
authors.lastname: Thys
authors.forename: Jean Marie
authors.initials: JM
authors.lastname: Ketelslegers
authors.forename: Agnes
authors.initials: A
authors.lastname: Pasquet
authors.forename: Nicolas
authors.initials: N
authors.lastname: Delvau
authors.forename: Véronique
authors.initials: V
authors.lastname: Deneys
authors.forename: Franck
authors.initials: F
authors.lastname: Verschuren
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D002637:Chest Pain / Q000175:diagnosis*; D004417:Dyspnea / Q000175:diagnosis*; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019095:Point-of-Care Systems; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers