title: Short-term volume and turgor regulation in yeast.
abstract: Volume is a highly regulated property of cells, because it critically affects intracellular concentration. In the present chapter, we focus on the short-term volume regulation in yeast as a consequence of a shift in extracellular osmotic conditions. We review a basic thermodynamic framework to model volume and solute flows. In addition, we try to select a model for turgor, which is an important hydrodynamic property, especially in walled cells. Finally, we demonstrate the validity of the presented approach by fitting the dynamic model to a time course of volume change upon osmotic shock in yeast.
authors.affiliation: Max Planck Institute for Molecular Genetics, Computational Systems Biology, Ihnestr. 63-73, 14195 Berlin, Germany. schaber@molgen.mpg.de
authors.forename: Jörg
authors.initials: J
authors.lastname: Schaber
authors.forename: Edda
authors.initials: E
authors.lastname: Klipp
mesh_terms: D008954:Models, Biological; D011312:Pressure; D012212:Rheology; D012441:Saccharomyces cerevisiae / Q000166:cytology*; D013997:Time Factors