title: Tetrahydrobostrycin and 1-deoxytetrahydrobostrycin, two new hexahydroanthrone derivatives, from a marine-derived fungus Aspergillus sp.
abstract: Two new hexahydroanthrones, tetrahydrobostrycin (1) and 1-deoxytetrahydrobostrycin (2), were isolated from a marine-derived fungus Aspergillus sp. strain 05F16 collected at the coral reef of Manado, Indonesia, together with bostrycin and abscisic acid. The structures of new compounds were determined on the basis of their spectral data. Compound 1 showed weak antibacterial activity against Staphylococcus aureus and Escherichia coli and 2 against S. aureus.
authors.affiliation: Tohoku Pharmaceutical University, Sendai, Japan.
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Xu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakazawa
authors.forename: Kazuyo
authors.initials: K
authors.lastname: Ukai
authors.forename: Hisayoshi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Remy E P
authors.initials: RE
authors.lastname: Mangindaan
authors.forename: Defny S
authors.initials: DS
authors.lastname: Wewengkang
authors.forename: Henki
authors.initials: H
authors.lastname: Rotinsulu
authors.forename: Michio
authors.initials: M
authors.lastname: Namikoshi
mesh_terms: D000040:Abscisic Acid; D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001230:Aspergillus / Q000737:chemistry* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects; D007214:Indonesia; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012623:Seawater / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000880:Anthraquinones; D000900:Anti-Bacterial Agents; C034287:bostrycin; D000040:Abscisic Acid