[Social-economic and obstetric factors associated to premature rupture of membranes].
BACKGROUND
The premature rupture of membranes is the delivery of amniotic liquid after 20 weeks of gestation and before the beginning of labour.


OBJECTIVE
To evaluate the association between premature rupture of membranes and sociodemographics and obstetrics antecedents.


METHODS
Unmatched case-control study carried out in patients from Hospital Civil de Culiacan, Sinaloa (Mexico), from January 2003 to December 2006. Risk factors frequency was compared in women with and without premature rupture of membranes (cases: 1,399; controls: 1,379). Most important variables were: socio-economic level, smoking, and gyneco-obstetric history (sexual partners, pregnancies, newborns, abortions, prenatal control and intergenesic interval). Odds ratio, crude and adjusted, and interval of confidence (IC 95%) were obtained by means of non-conditional logistic regression models.


RESULTS
Prevalence of premature rupture of membranes was 8.9%. Socio-economic level was similar in both groups. Premature rupture of membranes was associated with smoking, beginning of sexual activity, and intergenesic interval. History of two or more cesarean sections was considered a protective factor of premature rupture of membranes. Number of sexual partners was marginally meaningful (p = 0.053). Preterm birth frequency was higher in cases group. Resolution of pregnancy was the same for both groups (p = 0.233).


CONCLUSIONS
Premature rupture of membranes was significantly associated with smoking, beginning of sexual activiti, intergenesic interval and a preterm birth history. Two or more previous caesarean sections were considered as protective factor.
Ortiz
Fred Morgan
FM
Facultad de Medicina, Universidad Autónoma de Sinaloa, México. fmorganortiz@hotmail.com
Soto
Yamel Gómez
YG
del Refugio
Valenzuela González Irela
VG
Beltrán
Aurelio González
AG
Castro
Everardo Quevedo
EQ
Ramírez
Ignacio Osuna
IO
D016022:Case-Control Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D011247:Pregnancy; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult