title: Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogs.
abstract: Plague, caused by Yersinia pestis, is an exotic disease in North America circulating predominantly in wild populations of rodents and their fleas. Black-tailed prairie dogs (Cynomys ludovicianus) are highly susceptible to infection, often experiencing mortality of nearly all individuals in a town as a result of plague. The fleas of black-tailed prairie dogs are Oropsylla tuberculata cynomuris and Oropsylla hirsuta. We tested the efficiency of O. tuberculata cynomuris to transmit Y. pestis daily from 24 to 96 h postinfection and compared it to previously collected data for O. hirsuta. We found that O. tuberculata cynomuris has over threefold greater transmission efficiency (0.18 infected fleas transmit Y. pestis at 24 h postinfection) than O. hirsuta (0.05 fleas transmit). Using a simple model of flea-borne transmission, we combine these laboratory measurements with field data on monthly flea loads to compare the seasonal vectorial capacity of these two flea species. Coinciding with seasonal patterns of flea abundance, we find a peak in potential for flea-borne transmission in March, during high O. tuberculata cynomuris abundance, and in September-October when O. hirsuta is common. Our findings may be useful in determining the timing of insecticidal dusting to slow plague transmission in black-tailed prairie dogs.
authors.affiliation: Bacterial Diseases Branch, Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA. apwilder@lamar.colostate.edu
authors.forename: Aryn P
authors.initials: AP
authors.lastname: Wilder
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Eisen
authors.forename: Scott W
authors.initials: SW
authors.lastname: Bearden
authors.forename: John A
authors.initials: JA
authors.lastname: Montenieri
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Tripp
authors.forename: R Jory
authors.initials: RJ
authors.lastname: Brinkerhoff
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Gage
authors.forename: Michael F
authors.initials: MF
authors.lastname: Antolin
mesh_terms: D000818:Animals; D003120:Colorado / Q000453:epidemiology; D007303:Insect Vectors / Q000382:microbiology*; D010930:Plague / Q000453:epidemiology / Q000469:parasitology / Q000635:transmission*; D015995:Prevalence; D012376:Rodent Diseases / Q000453:epidemiology / Q000469:parasitology / Q000635:transmission*; D012589:Sciuridae / Q000382:microbiology* / Q000469:parasitology; D012621:Seasons; D005423:Siphonaptera / Q000382:microbiology* / Q000469:parasitology; D013045:Species Specificity; D013696:Temperature; D015010:Yersinia pestis / Q000472:pathogenicity*; D015047:Zoonoses
references.citation: Annu Rev Entomol. 2005;50:505-28
references.pmid: 15471529
references.citation: J Hyg (Lond). 1914 Jan;13(Suppl):423-39
references.pmid: 20474555
references.citation: Annu Rev Entomol. 1977;22:23-32
references.pmid: 319740
references.citation: Vector Borne Zoonotic Dis. 2008 Jun;8(3):359-67
references.pmid: 18454591
references.citation: Am J Trop Med Hyg. 2000 May;62(5):552-60
references.pmid: 11289663
references.citation: J Hyg (Lond). 1947 Aug;45(3):371-96
references.pmid: 20475778
references.citation: J Econ Entomol. 2007 Apr;100(2):545-50
references.pmid: 17461081
references.citation: Parazitologiia. 1990 Mar-Apr;24(2):106-12
references.pmid: 2195439
references.citation: J Med Entomol. 1998 Jul;35(4):415-22
references.pmid: 9701921
references.citation: J Wildl Dis. 1988 Jul;24(3):399-406
references.pmid: 3411698
references.citation: J Wildl Dis. 2007 Jul;43(3):425-31
references.pmid: 17699080
references.citation: Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6236-41
references.pmid: 16603630
references.citation: J Med Entomol. 2007 Jul;44(4):672-7
references.pmid: 17695024
references.citation: Bull World Health Organ. 1964;31:71-86
references.pmid: 14230896
references.citation: Exp Parasitol. 2007 Apr;115(4):369-78
references.pmid: 17092499
references.citation: J Vector Ecol. 2006 Dec;31(2):355-63
references.pmid: 17249353
references.citation: Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15380-5
references.pmid: 17032761
references.citation: J Med Entomol. 2003 May;40(3):329-37
references.pmid: 12943112
references.citation: Med Vet Entomol. 2007 Mar;21(1):97-102
references.pmid: 17373952
references.citation: J Med Entomol. 2003 Sep;40(5):718-22
references.pmid: 14596288
references.citation: J Med Entomol. 2007 Mar;44(2):175-8
references.pmid: 17427684
references.citation: Parazitologiia. 1990 Mar-Apr;24(2):151-4
references.pmid: 2195440
references.citation: J Med Entomol. 2007 Jul;44(4):678-82
references.pmid: 17695025