title: Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis.
abstract: BACKGROUND
  Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder that exhibits CD34 expression in the majority of lesional spindle cells. Several features of NSF bear similarity to Kaposi sarcoma.
  
  
  RESULTS
  Skin lesions procured from two male NSF patients were found to be negative for HHV8 (LNA-1) by means of immunohistochemistry.
  
  
  CONCLUSIONS
  This finding negates a role for HHV8 in the pathogenesis of NSF.
authors.affiliation: Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA. patrick.odonnell@bhs.org
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: O'Donnell
authors.forename: Wayne H
authors.initials: WH
authors.lastname: Duke
authors.forename: Liron
authors.initials: L
authors.lastname: Pantanowitz
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