title: Influence of age, central corneal thickness, and quality score on dynamic contour tonometry.
abstract: OBJECTIVE
  To compare the IOP measurements obtained with dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT), and to analyse the influence of central corneal thickness (CCT) and age on both measurements, and the influence of the quality score on DCT readings.
  
  
  METHODS
  A total of 500 healthy subjects with no prior history of glaucoma or ocular hypertension (age: 7-86 years) were consecutively recruited. GAT, DCT, and CCT measurements were obtained from both eyes of each individual, in this order, by three observers. The mean of five CCT measurements was used for analysis. DCT measurements were accepted when quality scores varied between 1 (higher quality) and 3 (lower quality).
  
  
  RESULTS
  Mean DCT measurements were 3.2 mmHg higher than GAT readings. CCT values varied between 449 and 653 microm. IOP measured by GAT correlated strongly with CCT (r(2)=0.28, P=<0.001), whereas DCT readings correlated poorly with CCT (r(2)=0.01, P=0.017). Both DCT (r(2)=<0.01, P=0.044) and GAT (r(2)=0.01, P=<0.001) measurements correlated poorly with age. Bland-Altmann analysis revealed disagreement between DCT and GAT readings, with 95% confidence intervals of +/-6.7 mmHg. Quality scores for DCT measurements were 1 (n=369, 36.9%), 2 (n=340, 34.0%), and 3 (n=291, 29.1%). DCT readings with quality score of 3 (18.8+/-3.4 mmHg) were significantly higher than those with quality scores of 1 (16.7+/-2.9 mmHg) and 2 (17.4+/-2.9 mmHg; P=<0.001).
  
  
  CONCLUSIONS
  DCT is not influenced by CCT, unlike GAT. Both DCT and GAT measurements are not influenced by age. DCT measurements with lower quality scores are associated with higher readings.
authors.affiliation: Department of Ophthalmology, State University of Campinas (UNICAMP), Campinas, SP, Brazil. jordao.marcelo@terra.com.br
authors.forename: M L S
authors.initials: ML
authors.lastname: Jordão
authors.forename: A Pedroso de Carvalho
authors.initials: AP
authors.lastname: Lupinacci
authors.forename: E L
authors.initials: EL
authors.lastname: Ferreira
authors.forename: I J F
authors.initials: IJ
authors.lastname: Enomoto
authors.forename: V P
authors.initials: VP
authors.lastname: Costa
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003315:Cornea / Q000473:pathology*; D003430:Cross-Sectional Studies; D005260:Female; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D011446:Prospective Studies; D014065:Tonometry, Ocular / Q000379:methods* / Q000592:standards; D055815:Young Adult