A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.
A new lignan glucoside (1) was isolated from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. (Verbenaceae), along with six known lignan glucosides and three known triterpenoids. The chemical structure of 1 was characterized as (+)-lyoniresinol 3 alpha-O-(6''-3,5-dimethoxy-4-hydroxybenzoyl)-beta-D-glucopyranoside on the basis of spectroscopic data. In addition, the radical-scavenging effect of four lignans on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Among the tested compounds, three compounds, including 1, showed almost the same scavenging activity as that of alpha-tocopherol.
Ono
Masateru
M
School of Agriculture, Tokai University, 5435 Minamiaso, Aso, Kumamoto, 869-1404, Japan. mono@agri.u-tokai.ac.jp
Mishima
Kenji
K
Yamasaki
Toru
T
Masuoka
Chikako
C
Okawa
Masafumi
M
Kinjo
Junei
J
Ikeda
Tsuyoshi
T
Nohara
Toshihiro
T
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification; D001713:Biphenyl Compounds / Q000737:chemistry; D032408:Callicarpa / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006834:Hydrazines / Q000737:chemistry; D017705:Lignans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D006834:Hydrazines; D017705:Lignans; D010851:Picrates; D010936:Plant Extracts; D014315:Triterpenes; C004931:1,1-diphenyl-2-picrylhydrazyl
J Nat Prod. 2004 Dec;67(12):2073-5
15620254
J Nat Med. 2008 Jan;62(1):101-6
18404353
Planta Med. 1992 Jun;58(3):270-2
17226467
Yakugaku Zasshi. 1968 Jun;88(6):678-83
5750296
Chem Phys Lipids. 1987 Nov-Dec;45(2-4):337-51
3319232
Chem Pharm Bull (Tokyo). 2000 Jul;48(7):1084-6
10923846
J Nat Med. 2008 Jan;62(1):47-51
18404341