Electroencephalographic evidence of sensory gating in the occipital visual cortex.
Sensory gating refers to the suppression of the neuronal response to a repeating stimulus and is considered a protection mechanism in the brain. In this study, we assessed gating of the mid-latency components of the visual evoked potentials (N75, P100, N150) in 11 healthy individuals using a paired-flash paradigm. A significant decrease of P100 and N150 amplitudes was shown; additionally, a significant increase in the latency of N75 and P100 for the second stimulus of the pair compared with the first one was also observed. Absolute power of the stimulus 2 signal at theta frequency was significantly suppressed as compared with the stimulus 1 signal. These results indicate a gating effect in the visual modality, reflected in both time-domain and frequency-domain measures.
Gjini
Klevest
K
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 48207, USA. kgjini@med.wayne.edu
Sundaresan
Karthik
K
Boutros
Nash N
NN
D000328:Adult; D001921:Brain / Q000502:physiology; D004569:Electroencephalography; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology*; D013647:Task Performance and Analysis; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*