Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose.
A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of intravenous sodium bicarbonate.
Chan
Ho Yin
HY
Hong Kong Poison Information Centre, Hong Kong. henrychanhy@yahoo.com
Chan
Yiu Cheung
YC
Lau
Fei Lung
FL
D000328:Adult; D000639:Amitriptyline / Q000506:poisoning*; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning*; D053840:Brugada Syndrome / Q000139:chemically induced*; D062787:Drug Overdose / Q000188:drug therapy; D004562:Electrocardiography; D006801:Humans; D008297:Male; D017693:Sodium Bicarbonate / Q000627:therapeutic use; D013405:Suicide
D000929:Antidepressive Agents, Tricyclic; D000639:Amitriptyline; D017693:Sodium Bicarbonate