title: [Temporospatial expression of cyclin G1 in normal human endometria].
abstract: OBJECTIVE
  To study the temporospatial expression of cyclin G1 protein and mRNA in normal human endometrium and its physiological implications.
  
  
  METHODS
  Human endometria samples were taken from 15 women in proliferative phase, 11 in early secretory phase, and 15 in mid-late secretary phase. Cyclin G1 protein and mRNA in the normal human endometria were measured by immunohistochemistry and in situ hybridization, respectively.
  
  
  RESULTS
  The expression of cyclin G1 protein in the epithelium cells was low in proliferative phase. The expression increased at early secretary phase and reached the highest at mid-late secretary phase. The expression of cyclin G1 protein in stromal cells only appeared at mid-late secretary phase. The cyclin G1 protein was localized in nucleus. The expression of cyclin G1 mRNA was localized in cytoplasma, but had similar cycles as the expression of cyclin G1 protein.
  
  
  CONCLUSIONS
  The expression of Cyclin G1 in normal human endometria is progesterone dependence.
authors.affiliation: Department of Physiology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Kang-zhuo
authors.initials: KZ
authors.lastname: Baima
authors.forename: Ji-Mei
authors.initials: JM
authors.lastname: Tian
authors.forename: Kai-xuan
authors.initials: KX
authors.lastname: Yang
authors.forename: Ming-rong
authors.initials: MR
authors.lastname: Qie
authors.forename: Jin-hu
authors.initials: JH
authors.lastname: Zhang
authors.forename: Ya-ping
authors.initials: YP
authors.lastname: He
authors.forename: Li-min
authors.initials: LM
authors.lastname: Yue
mesh_terms: D000328:Adult; D056746:Cyclin G; D056766:Cyclin G1; D016213:Cyclins / Q000096:biosynthesis* / Q000235:genetics; D004717:Endometrium / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D008597:Menstrual Cycle / Q000502:physiology*; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D013997:Time Factors
chemical_list: C534702:CCNG1 protein, human; D056746:Cyclin G; D056766:Cyclin G1; D016213:Cyclins; D012333:RNA, Messenger