Reduced-representation methylation mapping.
The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.
Jeddeloh
Jeffrey A
JA
Roche NimbleGen Inc, Research and Development, 500 S. Rosa Rd, Madison, WI 53719, USA. jeffrey.jeddeloh@roche.com
Greally
John M
JM
Rando
Oliver J
OJ
D000818:Animals; D003596:Cytosine / Q000378:metabolism; D019175:DNA Methylation / Q000502:physiology; D044127:Epigenesis, Genetic; D023281:Genomics / Q000379:methods; D051379:Mice; D017422:Sequence Analysis, DNA / Q000379:methods*
D003596:Cytosine
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