Capillary malformation of the lower lip, lymphatic malformation of the face and neck, asymmetry and partial/generalized overgrowth (CLAPO): report of six cases of a new syndrome/association.
We report on six patients with clinical findings consisting of (1) Capillary malformation (CM) of the lower lip; (2) Lymphatic malformation (LM) of the face/neck; (3) Asymmetry of face and limbs, and (4) Partial/generalized Overgrowth. This constellation of findings has been observed in six unrelated patients, constituting a likely "new" syndrome/association of capillary-lymphatic-venous malformation and asymmetric overgrowth.
López-Gutiérrez
Juan Carlos
JC
Section of Plastic and Reconstructive Surgery, Department of Pediatric Surgery, Hospital Universitario La Paz, Autónoma University of Madrid, Madrid, Spain.
Lapunzina
Pablo
P
D000015:Abnormalities, Multiple / Q000473:pathology; D000328:Adult; D015901:Angiography, Digital Subtraction; D002196:Capillaries / Q000002:abnormalities; D002648:Child; D005145:Face; D005146:Facial Asymmetry / Q000151:congenital*; D005260:Female; D006801:Humans; D007223:Infant; D008046:Lip / Q000098:blood supply; D035002:Lower Extremity; D044148:Lymphatic Abnormalities / Q000175:diagnosis / Q000473:pathology; D042601:Lymphatic Vessels / Q000002:abnormalities; D008279:Magnetic Resonance Imaging; D008297:Male; D009333:Neck; D019339:Port-Wine Stain / Q000473:pathology; D013577:Syndrome; D014059:Tongue / Q000002:abnormalities; D054079:Vascular Malformations / Q000175:diagnosis / Q000473:pathology