title: Hyperbaric oxygen therapy in Thai autistic children.
abstract: BACKGROUND
  Autism is a developmental and behavioral pattern, the triad of impairments, 1. social interaction, 2. social communication, 3. imagination. Their memories are seemingly in picture or photo records. Difficulties in the treatment, management, and handling of autistic children are the main problems. Hyperbaric oxygen therapy (HBOT) is a modern treatment in Thailand for nitrogen imbalance (Decompression sickness syndrome or Caisson disease). HBOT can increase plasma oxygen to the tissues including the brain.
  
  
  OBJECTIVE
  To determine whether Hyperbaric Oxygen Therapy is safe to use in children with autism, and has a statistically significant effect on autistic symptoms. This is the first study in Thailand.
  
  
  METHODS
  Thai Autistic children (n = 7) received HBOT (1.3 atm., 10 sessions) treatment. Assessment was done before and after treatment in five domains: Social development, Fine motor and Eye-hand coordination, Language development, Gross motor development, Self-help skills.
  
  
  RESULTS
  Improvement was shown in five domains with a significant level. Seventy-five percent of children shown improvement while 25% did not seem to respond to the treatment.
  
  
  CONCLUSIONS
  HBOT is a new treatment for Thai autistic children. Many scientific studies recently have shown that HBOT could be an effective treatment for autistic children. It could improve the major autistic symptoms.
authors.affiliation: Department of Medicine, Phuket Hospital, Phuket, Thailand. director@vachiraphuket.go.th
authors.forename: Jessada
authors.initials: J
authors.lastname: Chungpaibulpatana
authors.forename: Tappana
authors.initials: T
authors.lastname: Sumpatanarax
authors.forename: Noppol
authors.initials: N
authors.lastname: Thadakul
authors.forename: Chansin
authors.initials: C
authors.lastname: Chantharatreerat
authors.forename: Maytinee
authors.initials: M
authors.lastname: Konkaew
authors.forename: Methira
authors.initials: M
authors.lastname: Aroonlimsawas
mesh_terms: D000975:Antioxidants; D001321:Autistic Disorder / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D006931:Hyperbaric Oxygenation; D007398:Interpersonal Relations; D008297:Male; D018384:Oxidative Stress; D010865:Pilot Projects; D013785:Thailand
chemical_list: D000975:Antioxidants