Tetrahydrobostrycin and 1-deoxytetrahydrobostrycin, two new hexahydroanthrone derivatives, from a marine-derived fungus Aspergillus sp.
Two new hexahydroanthrones, tetrahydrobostrycin (1) and 1-deoxytetrahydrobostrycin (2), were isolated from a marine-derived fungus Aspergillus sp. strain 05F16 collected at the coral reef of Manado, Indonesia, together with bostrycin and abscisic acid. The structures of new compounds were determined on the basis of their spectral data. Compound 1 showed weak antibacterial activity against Staphylococcus aureus and Escherichia coli and 2 against S. aureus.
Xu
Jinzhong
J
Tohoku Pharmaceutical University, Sendai, Japan.
Nakazawa
Takahiro
T
Ukai
Kazuyo
K
Kobayashi
Hisayoshi
H
Mangindaan
Remy E P
RE
Wewengkang
Defny S
DS
Rotinsulu
Henki
H
Namikoshi
Michio
M
D000040:Abscisic Acid; D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001230:Aspergillus / Q000737:chemistry* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects; D007214:Indonesia; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012623:Seawater / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; C034287:bostrycin; D000040:Abscisic Acid