[Radical cystectomy as a muscle-invasive bladder cancer treatment in elderly patients].
BACKGROUND
Radical cystectomy in elderly is a controversial issue that increases importance overtime because average life span is growing.


OBJECTIVE
The purpose of our work was to analize the differences about perioperative and later outcomes between ages of patients with muscle-invasive bladder neoplasm treated with radical cystectomy.


METHODS
We retrospectively reviewed the records of patients who underwent radical cystectomy for muscle-invasive bladder cancer. Two age groups were compared: < 70-years-old at time of cystectomy (n = 55) and > or = 70 years (n = 57).


RESULTS
There was no difference between both age groups about: time of surgery, intraoperative complications (< 70 = 21,8%, > or = 70 = 31,6%), postoperative mortality (< 70 = 3,6%, > or = 70 = 8,8%), minor (< 70 = 18,2%, > or = 70 = 26,3%) and major medical postoperative complications (< 70 = 7,3%, > or = 70 = 8,8%), late outcomes as cancer-specific morby-mortality and actuarial overall survival stratified by patient age. The rate of major postoperative complications (< 70 = 23,6%, > or = 70 = 43,9%) as well as the mean length of hospital stay (< 70 = 10,2, > or = 70 = 15,2 days) differed significantly between the two age groups. Age and cardiovascular risk factors were independient predictive factors of mayor postoperative complications.


CONCLUSIONS
Radical cystectomy could be performed in carefully selected elderly patients.
March Villalba
J A
JA
Servicio de Urología del Hospital Clínico Universitario de Valencia, Valencia. joseantoniomarch@hotmail.com
Martínez Jabaloyas
J M
JM
Pastor Hernández
F
F
Günthner Stefan
F J
FJ
Rodríguez Navarro
R
R
Chuan Nuez
P
P
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015653:Cystectomy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*