title: Design of an ultimate quencher free molecular beacon containing pyrrolocytidine-guanine base pair.
abstract: A novel quencher free molecular beacon was designed in which fluorophore-labelled pyrrolocytidine was placed away from the stem terminal. This new type of MB was used for the detection of a target DNA with an excellent efficiency.
authors.affiliation: Department of Materials Chemistry and Engineering and NEWCAT Institute, School of Engineering, Nihon University, Koriyama, Fukushima 963-8642, Japan. saito@chem.ce.nihon-u.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Saito
authors.forename: Yuta
authors.initials: Y
authors.lastname: Shinohara
authors.forename: Subhendu Sekhar
authors.initials: SS
authors.lastname: Bag
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Takeuchi
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Isao
authors.initials: I
authors.lastname: Saito
mesh_terms: D020029:Base Pairing; D003562:Cytidine / Q000031:analogs & derivatives* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006147:Guanine / Q000737:chemistry*; D015345:Oligonucleotide Probes / Q000138:chemical synthesis / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D017422:Sequence Analysis, DNA; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D015345:Oligonucleotide Probes; D011758:Pyrroles; D003562:Cytidine; D006147:Guanine