title: Snf2 proteins in plants: gene silencing and beyond.
abstract: Proteins belonging to the conserved and diversified Snf2 family provide the ATP-driven motor subunits for remodelling systems, which control the accessibility of chromatin DNA. The 41 proteins of this family encoded in the Arabidopsis genome fall into 19 distinct subfamilies. Although most of the plant Snf2 proteins studied so far retain the functional specialization of their yeast and animal homologues, some have been adapted for functions occurring only in plants. We present a comprehensive in silico characterization of the domain architecture of the complete set of Arabidopsis Snf2 proteins. In combination with recent data on the molecular mechanisms underlying the functions of some yeast and animal homologues, this offers an insight into the different roles of Snf2 proteins in plants.
authors.affiliation: Laboratory of Bioinformatics and Bioengineering, Interdisciplinary Center for Mathematical and Computational Modelling, University of Warsaw, Warsaw, Poland.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Knizewski
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Ginalski
authors.forename: Andrzej
authors.initials: A
authors.lastname: Jerzmanowski
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D005810:Multigene Family
chemical_list: D029681:Arabidopsis Proteins; D002843:Chromatin