[Resected lung cancer with production of CA19-9].
We report 2 cases of resected CA19-9 producing adenocarcinoma of the lung. Immunohistochemical studies of the specimens in 2 cases showed positive staining for CA19-9 in most of tumor cells. The serum CA19-9 levels decreased after operations and effective chemotherapy in these cases. But the serum CA19-9 levels increased with regrowth of tumors or with no therapeutic gain by chemotherapy. The serum CA19-9 level was useful to evaluate the therapeutic effect of surgery and chemotherapy, and may be effective in detecting the recurrence of lung cancer.
Abiko
T
T
Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Koizumi
S
S
Takanami
I
I
D000230:Adenocarcinoma / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000096:biosynthesis* / Q000097:blood; D018395:CA-19-9 Antigen / Q000096:biosynthesis* / Q000097:blood; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D000077143:Docetaxel; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery*; D008297:Male; D011013:Pneumonectomy; D043823:Taxoids / Q000008:administration & dosage; D016896:Treatment Outcome
D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D043823:Taxoids; D000077143:Docetaxel; D016190:Carboplatin