title: High-resolution transmission electron microscopy study of nanostructured hydroxyapatite.
abstract: Crystalline properties of synthetic nanostructured hydroxyapatite (n-HA) were studied using high-resolution transmission electron microscopy. The focal-series-restoration technique, obtaining exit-plane wavefunction and spherical aberration-corrected images, was successfully applied for the first time in this electron-beam-susceptible material. Multislice simulations and energy dispersive X-ray spectroscopy were also employed to determine unequivocally that n-HA particles of different size preserve stoichiometric HA-like crystal structure. n-HA particles with sizes of twice the HA lattice parameter were found. These results can be used to optimize n-HA sinterization parameters to improve bioactivity.
authors.affiliation: Brazilian Synchrotron Light Laboratory, Caixa Postal 6192, Campinas-SP 13083-970, Brazil.
authors.forename: Daniel
authors.initials: D
authors.lastname: Biggemann
authors.forename: Marcelo H Prado
authors.initials: MH
authors.lastname: da Silva
authors.forename: Alexandre M
authors.initials: AM
authors.lastname: Rossi
authors.forename: Antonio J
authors.initials: AJ
authors.lastname: Ramirez
mesh_terms: D017886:Durapatite / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D017886:Durapatite