title: Relationship between hypomagnesemia and glucose homeostasis.
abstract: BACKGROUND
  Controversial data are available on the relationship between magnesium metabolism and glucose homeostasis.
  
  
  METHODS
  We performed a retrospective analysis to retrieve results of serum magnesium and fasting plasma glucose (FPG) tests (7,659 outpatients >35 years old).
  
  
  RESULTS
  Subjects with FPG value > 7.0 mmol/L were more likely to had hypomagnesemia. The frequency of hypomagnesemia was also significantly higher among those with high FPG values > 7.0 mmol/L. In multivariable linear regression analysis, magnesium was significantly associated with FPG only in patients with FPG > 7.0 mmol/L.
  
  
  CONCLUSIONS
  Magnesium metabolism could be implicated in the glucose homeostasis, especially in patients with FPG values suggestive for diabetes.
authors.affiliation: Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università di Verona, Italy. martina.montagnana@med.lu.se
authors.forename: Martina
authors.initials: M
authors.lastname: Montagnana
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lippi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Targher
authors.forename: Gian Luca
authors.initials: GL
authors.lastname: Salvagno
authors.forename: Gian Cesare
authors.initials: GC
authors.lastname: Guidi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose; D008274:Magnesium