title: Subacute brainstem angioencephalopathy: favorable outcome with anticoagulation therapy.
abstract: We present a patient who developed progressive neurological disease caused by lesions histologically compatible with those observed in subacute brainstem angioencephalopathy. The patient was treated with low-molecular weight heparin, and treatment response was monitored clinically and with MRI. Anticoagulation therapy stopped progression of the neurological deficit and led to improvement of MRI findings. This report further supports the existence of subacute brainstem angioencephalopathy as a characteristic disease entity and gives insight into possible therapeutic approach with anticoagulation treatment.
authors.affiliation: University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Zagreb, Croatia. mhabek@mef.hr
authors.forename: Mario
authors.initials: M
authors.lastname: Habek
authors.forename: Svjetlana
authors.initials: S
authors.lastname: Supe
authors.forename: Zdravka
authors.initials: Z
authors.lastname: Poljaković
authors.forename: Ellen
authors.initials: E
authors.lastname: Gelpi
authors.forename: François
authors.initials: F
authors.lastname: Alesch
authors.forename: David
authors.initials: D
authors.lastname: Ozretić
authors.forename: Vesna V
authors.initials: VV
authors.lastname: Brinar
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D001933:Brain Stem / Q000473:pathology*; D002550:Cerebral Veins / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D000925:Anticoagulants