title: Hyperkinetic movement disorder in a child treated by globus pallidus stimulation.
abstract: We report herein the case of a 9-year-old girl with life-threatening hyperkinetic involuntary movement of unknown etiology. Medical treatment was ineffective for her stereotypy and choreoathetotic/ballistic movements, but bilateral stimulation of the globus pallidus immediately alleviated these symptoms. Pallidal deep-brain stimulation may be considered the therapy of choice for children with intractable hyperkinetic movement disorders.
authors.affiliation: Department of Child Neurology, National Center Hospital of Neurology and Psychiatry, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Sato
authors.forename: Eiji
authors.initials: E
authors.lastname: Nakagawa
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Saito
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Komaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakuma
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugai
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Takanobu
authors.initials: T
authors.lastname: Kaido
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Nakama
authors.forename: Taisuke
authors.initials: T
authors.lastname: Otsuki
mesh_terms: D000367:Age Factors; D001264:Athetosis / Q000503:physiopathology / Q000628:therapy; D001479:Basal Ganglia / Q000033:anatomy & histology / Q000503:physiopathology; D002648:Child; D002819:Chorea / Q000503:physiopathology / Q000628:therapy; D046690:Deep Brain Stimulation / Q000295:instrumentation / Q000379:methods*; D002658:Developmental Disabilities / Q000150:complications / Q000503:physiopathology; D004567:Electrodes, Implanted; D005260:Female; D005334:Fever / Q000150:complications; D005917:Globus Pallidus / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D006948:Hyperkinesis / Q000503:physiopathology / Q000628:therapy*; D009069:Movement Disorders / Q000503:physiopathology / Q000628:therapy*; D009434:Neural Pathways / Q000033:anatomy & histology / Q000503:physiopathology; D019956:Stereotypic Movement Disorder / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome