TESE: generating specific protein structure test set ensembles.
TESE is a web server for the generation of test sets of protein sequences and structures fulfilling a number of different criteria. At least three different use cases can be envisaged: (i) benchmarking of novel methods; (ii) test sets tailored for special needs and (iii) extending available datasets. The CATH structure classification is used to control structural/sequence redundancy and a variety of structural quality parameters can be used to interactively select protein subsets with specific characteristics, e.g. all X-ray structures of alpha-helical repeat proteins with more than 120 residues and resolution <2.0 A. The output includes FASTA-formatted sequences, PDB files and a clickable HTML index file containing images of the selected proteins. Multiple subsets for cross-validation are also supported.


BACKGROUND
The TESE server is available for non-commercial use at URL: http://protein.bio.unipd.it/tese/.
Sirocco
Francesco
F
Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy.
Tosatto
Silvio C E
SC
D019295:Computational Biology; D030562:Databases, Protein; D020407:Internet; D008958:Models, Molecular; D011487:Protein Conformation; D011506:Proteins / Q000032:analysis* / Q000737:chemistry*
D011506:Proteins