title: A comprehensive review of the psychological effects of brainwave entrainment.
abstract: OBJECTIVE
  Brainwave entrainment (BWE), which uses rhythmic stimuli to alter brainwave frequency and thus brain states, has been investigated and used since the late 1800s, yet many clinicians and scientists are unaware of its existence. We aim to raise awareness and discuss its potential by presenting a systematic review of the literature from peer-reviewed journals on the psychological effects of BWE.
  
  
  METHODS
  Terms used to describe BWE and psychological outcomes were used to search English language studies from OVID Medline (1950-2007), PsychInfo (1806-2007), and Scopus.
  
  
  METHODS
  Twenty studies selected satisfied the following criterion: studies needed to use rhythmic stimuli with the aim ofaffecting psychological outcomes. Peer-reviewed experimental and quasi-experimental studies were accepted. Case studies and review articles were excluded. Psychological outcomes were measured using standard assessment methods or as deemed appropriate by peer review.
  
  
  METHODS
  Other clinical measurements, including electroencephalogram response, galvanic skin response, and neurotransmitter levels were not included.
  
  
  RESULTS
  Psychological outcomes addressed cognition, stress and anxiety, pain relief, headaches or migraines, mood, behavior, and premenstrual syndrome (PMS). Protocols included the use of single, alternating, ascending, or descending frequencies or were determined by the subject, using auditory and/or photic stimulation. Studies examined single session effects and/or longer-term multiple session effects.
  
  
  CONCLUSIONS
  Findings to date suggest that BWE is an effective therapeutic tool. People suffering from cognitive functioning deficits, stress, pain, headache/migraines, PMS, and behavioral problems benefited from BWE. However, more controlled trials are needed to test additional protocols with outcomes.
authors.affiliation: Transparent Corporation, Columbus, Ohio, USA.
authors.forename: Tina L
authors.initials: TL
authors.lastname: Huang
authors.forename: Christine
authors.initials: C
authors.lastname: Charyton
mesh_terms: D000161:Acoustic Stimulation; D001296:Audiovisual Aids; D001921:Brain / Q000502:physiology; D000529:Complementary Therapies / Q000379:methods* / Q000523:psychology*; D005074:Evoked Potentials, Visual; D020773:Headache Disorders / Q000628:therapy*; D006801:Humans; D001523:Mental Disorders / Q000523:psychology / Q000628:therapy*; D010146:Pain / Q000523:psychology; D059408:Pain Management; D010775:Photic Stimulation; D010812:Physical Stimulation / Q000379:methods*