title: Influence of the ageing phenomenon on the low-frequency electrical impedance behavior of naphazoline hydrochloride solutions and paracetamol syrup.
abstract: The influence of the ageing process on the low frequency behavior of some electrical parameters of naphazoline hydrochloride solutions at 0.5% and 1% in concentration and of 2% paracetamol syrup, is studied. The impedance measurements were performed, in the range between 200 Hz and 1 MHz, using an impedance analyzer and a cell for liquids with plane parallel electrodes whose separation can be changed by using a set of spacers, provided by the manufacturer, in order to get better control of the influence of electrodes polarization effect. The ageing state was artificially generated by dilution and/or heating separated procedures. The results show that this dielectric technique can be used as a good quality complementary control technique.
authors.affiliation: Laboratorio de Dieléctricos, Departamento de Física, Facultad de Ciencias Exactas y Tecnología, Universidad Nacional de Tucumán, Tucumán, Argentina. pbrito@herrera.unt.edu.ar
authors.forename: Pedro C
authors.initials: PC
authors.lastname: Brito
authors.forename: Magdalena
authors.initials: M
authors.lastname: Mechetti
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Gotter
authors.forename: David J
authors.initials: DJ
authors.lastname: Merep
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000737:chemistry*; D000281:Administration, Intranasal; D000465:Algorithms; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000737:chemistry*; D004338:Drug Combinations; D017097:Electric Impedance; D004566:Electrodes; D009278:Naphazoline / Q000008:administration & dosage / Q000737:chemistry*; D014663:Nasal Decongestants / Q000008:administration & dosage / Q000737:chemistry*; D019999:Pharmaceutical Solutions; D013535:Suspensions
chemical_list: D018712:Analgesics, Non-Narcotic; D004338:Drug Combinations; D014663:Nasal Decongestants; D019999:Pharmaceutical Solutions; D013535:Suspensions; D000082:Acetaminophen; D009278:Naphazoline