title: Factors affecting post minimally invasive direct coronary artery bypass grafting incidence of myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting and mortality of cardiac origin.
abstract: In the present study we identify parameters which influence the incidence of myocardial infarction (MI), need for percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) and cardiac mortality after minimal invasive coronary artery bypass grafting (MIDCABG). With a mean follow-up of 30+/-11.2 months, 390 patients were assessed with Wald test-corrected chi(2) analysis to identify preoperative factors which correlate with a higher incidence of post-MIDCABG MI, PCI, CABG and mortality from cardiac causes. We found an increased incidence of postoperative MI in patients with 2-vessel (8.7%) and 3-vessel (7.7%) vs. 1.3% 1-vessel coronary artery disease (CAD) (P=0.023), and in patients with preceding cardiac procedure (CABG and PCI: 8.4% vs. 2.0% without, P=0.023). Also diabetes was associated with higher post-MIDCABG frequency of MI (P=0.035). Severity of angina was associated with lesser post-MIDCAB-PCI (P=0.011) while preceding CABG predicted a higher incidence (P=0.012). Preoperative low ejection fraction (EF) (multivariate, P<0.001), preoperative MI (P=0.007) and extent of CAD (P=0.001) were associated with a higher post-MIDCABG mortality. None of the parameters correlated with subsequent CABG MIDCABG. The extent and history of CAD, history of cardiac interventions and low EF seem to influence the outcome adversely and should be considered deciding pro or against the MIDCAB-option.
authors.affiliation: Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University of Singapore, Singapore. surtk@nus.edu.sg
authors.forename: Theo
authors.initials: T
authors.lastname: Kofidis
authors.forename: Hans
authors.initials: H
authors.lastname: Gerd Paeschke
authors.forename: Artur
authors.initials: A
authors.lastname: Lichtenberg
authors.forename: Maximilian
authors.initials: M
authors.lastname: Emmert
authors.forename: Felix
authors.initials: F
authors.lastname: Woitek
authors.forename: Vassilios
authors.initials: V
authors.lastname: Didilis
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.forename: Uwe
authors.initials: U
authors.lastname: Klima
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000209:etiology; D015906:Angioplasty, Balloon, Coronary / Q000401:mortality; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality; D003324:Coronary Artery Disease / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D048909:Diabetes Complications / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009203:Myocardial Infarction / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D018579:Patient Selection; D012086:Reoperation; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D013318:Stroke Volume; D013997:Time Factors; D016896:Treatment Outcome