title: Managing acute on chronic respiratory failure: a guide to non-invasive ventilation.
abstract: Acute-on-chronic respiratory failure is becoming an increasingly common medical emergency, mostly as a result of exacerbations of chronic obstructive pulmonary disease. It is associated with high mortality rates and so practising the best evidence-based management is vital.
authors.affiliation: Royal Free and University College Medical School, London NW3 2PF.
authors.forename: J J P
authors.initials: JJ
authors.lastname: Goldring
authors.forename: J A
authors.initials: JA
authors.lastname: Wedzicha
mesh_terms: D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications; D004315:Doxapram / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009468:Neuromuscular Diseases / Q000150:complications; D010100:Oxygen / Q000627:therapeutic use; D010166:Palliative Care / Q000379:methods; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D012121:Respiration, Artificial / Q000379:methods*; D012131:Respiratory Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D019141:Respiratory System Agents / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D019141:Respiratory System Agents; D004315:Doxapram; D010100:Oxygen