title: [Growth hormone therapy for short children born small for gestational age].
abstract: Approximately 10% of all children born small for gestational age (SGA) fail to achieve sufficient catch-up growth and remain with short stature throughout childhood and adult life. Abnormalities of the GH/IGF-1 axis are not always identified. Several studies have demonstrated that GH is an effective and well-tolerated therapy and most children will reach a normal adult height. In this review, it can be seen the encouraging results of GH treatment in growth-retarded children born SGA highlighting the benefits of early treatment.
authors.affiliation: Departamento de Pediatria, Serviço de Endocrinologia e Metabologia do Paraná, Universidade Federal do Paraná, Curitiba, PR, Brazil. margabogus@uol.com.br
authors.forename: Margaret C S
authors.initials: MC
authors.lastname: Boguszewski
authors.forename: César Luiz
authors.initials: CL
authors.lastname: Boguszewski
mesh_terms: D001827:Body Height / Q000187:drug effects*; D002648:Child; D019382:Human Growth Hormone / Q000097:blood / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000254:growth & development*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D050356:Lipid Metabolism / Q000187:drug effects
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I