Ovarian and multiple lymph nodes recurrence of acute lymphoblastic leukemia: a case report and review of literature.
Ovarian involvement of acute lymphoblastic leukemia (ALL) without relapse in the bone marrow or other extramedullary site is rare. We report a case of ovarian relapse in a 13-year-old girl who was diagnosed with ALL at the age of 11. A complete remission was induced with the Children Cancer Group 1882 protocol for high-risk-groups. After maintenance chemotherapy, the patient remained in relatively good health for the next 4 months. The patient presented with intermittent colicky right lower quadrant pain of 1-day duration. The pelvic ultrasound (US) showed a lobulated mixed echogenic mass in the right ovary, and an exploratory laparotomy was performed. Although uncommon, ovarian recurrence after treatment for ALL should be considered in patients with suggestive symptoms. Regular pelvic US is easy to perform and has no side effects and can help detect ovarian tumors early in ALL survivors.
Kim
Jong Woon
JW
Department of Obstetrics and Gynecology, Chonnam National University Medical School, 8 Hakdong, Donggu, Gwangju, 501-190, Korea.
Cho
Moon Kyoung
MK
Kim
Cheol Hong
CH
Kang
Woo Dae
WD
Kook
Hoon
H
Kim
Yoon Ha
YH
Choi
Ho Sun
HS
Kim
Seok Mo
SM
D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012008:Recurrence
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