title: Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer.
abstract: Agaricus blazei Murill (AbM) is an edible, medicinal mushroom of Brazilian origin. It is used traditionally against a range of diseases, including cancer and chronic hepatitis, and has been cultivated commercially for the health food market. AbM has recently been shown to have strong immunomodulating properties, which has led to increasing scientific interest. In this article, we review current knowledge as to the immunological properties of AbM, and its possible clinical use in connection with infections and cancer. We also present some novel findings, which point to highly different biological potency between AbM extracts of different source and manufacturing.
authors.affiliation: Department of Immunology and Transfusion Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. geir.hetland@medisin.uio.no
authors.forename: G
authors.initials: G
authors.lastname: Hetland
authors.forename: E
authors.initials: E
authors.lastname: Johnson
authors.forename: T
authors.initials: T
authors.lastname: Lyberg
authors.forename: S
authors.initials: S
authors.lastname: Bernardshaw
authors.forename: A M A
authors.initials: AM
authors.lastname: Tryggestad
authors.forename: B
authors.initials: B
authors.lastname: Grinde
mesh_terms: D000364:Agaricus / Q000737:chemistry; D000818:Animals; D006801:Humans; D007107:Immune System / Q000187:drug effects*; D007239:Infections / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy*