Risk of intravascular cardiac device infections in patients with bacteraemia: impact on device removal.
The risk of intravascular cardiac device infection (ICDI) has increased significantly over the last decade and is rising faster than the corresponding increase in device implantations. ICDIs may consist of pocket infections, wire infections, wire infections complicated by endocarditis, or combinations of these. In this review, we examine the microbiology of ICDIs, focusing on the risk of developing ICDI following bloodstream infections with key pathogens such as Staphylococcus aureus, coagulase-negative staphylococci, enterococci, etc., as well as the pathophysiology of these infections.
Corey
G Ralph
GR
Department of Medicine and Duke Clinical Research Institute, Durham, NC, USA. corey001@mc.duke.edu
Lalani
Tahaniyat
T
D016470:Bacteremia / Q000150:complications*; D020878:Device Removal; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000473:pathology; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology / Q000473:pathology; D006350:Heart Valve Prosthesis / Q000382:microbiology*; D006801:Humans; D016459:Prosthesis-Related Infections / Q000453:epidemiology* / Q000628:therapy*