title: A case of diode laser photocoagulation in the treatment of choroidal metastasis of breast carcinoma.
abstract: To report a single case of improvement on choroidal metastasis of breast cancer after laser photocoagulation. A 52-year-old female patient who complained of visual disturbance of the right eye with multiple states of metastasis of breast carcinoma. On initial examination, the right best-corrected visual acuity was 0.63. Right fundoscopy revealed an elevated mass-like lesion temporal to the macule with serous retinal detachment. The mass had a 3.5-disc diameter. A right fluorescein angiogram revealed hypofluorescence during the prearterial and arteriovenous phase and hyperfluorescence during the venous phase. The venous phase showed almost total masking of background choroidal fluorescence at the elevated lesion because of leakage and neovascularization. The patient was treated 4 times by diode laser photocoagulation in addition to chemotherapy. Fifty days after the diode laser treatments, the funduscopy examination and fluorescein angiogram revealed that the serous retinal detachment had been absorbed, the choroid had become flat, the lesion had been reduced in size and hyperfluorescence. The right best-corrected visual acuity was improved to 0.8. Laser photocoagulation appears not to cause any problems for the patient and may be an efficient treatment for patients with choroidal breast carcinoma.
authors.affiliation: Department of Ophthalmology, College of Medicine, Kosin University, Pusan, Korea.
authors.forename: Sang Joon
authors.initials: SJ
authors.lastname: Lee
authors.forename: Soo Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Shin Dong
authors.initials: SD
authors.lastname: Kim
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000556:secondary / Q000601:surgery*; D002830:Choroid Neoplasms / Q000556:secondary / Q000601:surgery*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008875:Middle Aged; D014792:Visual Acuity
references.citation: Ophthalmic Surg Lasers. 2001 Jul-Aug;32(4):294-9
references.pmid: 11475394
references.citation: J Med. 1986;17(1):1-11
references.pmid: 3473153
references.citation: Ophthalmology. 2005 Feb;112(2):337-43
references.pmid: 15691572
references.citation: Arch Ophthalmol. 1988 May;106(5):603-7
references.pmid: 2451906
references.citation: Birth Defects Orig Artic Ser. 1988;24(1):121-7
references.pmid: 2460149
references.citation: Med Oncol. 2004;21(3):217-21
references.pmid: 15456948
references.citation: Ophthalmologica. 2004 Nov-Dec;218(6):372-7
references.pmid: 15564754
references.citation: Am J Ophthalmol. 2003 Aug;136(2):264-71
references.pmid: 12888048