Long-term (7-year-) treatment with lamivudine monotherapy in HBV-associated glomerulonephritis.
Glomerulonephritis (GN) is an uncommon but well-described complication of chronic hepatitis B virus (HBV) infection. HBV-related membranous nephropathy (MN) may lead to renal failure in 1/3 of the patients and spontaneous remission is rare. There is no standard therapy for HBV-associated MN. We report a case of a 28-year-old man with HBV-associated MN due to pre-core HBV mutant with complete remission under an ongoing 7-year lamivudine monotherapy.
Mesquita
M
M
Nephrology and Dialysis Unit, Department of Internal Medicine, CHU-Brugmann, Université Libre de Bruxelles, Belgium. maria.mesquita@chu-brugmann.be
Lasser
L
L
Langlet
P
P
D000328:Adult; D004334:Drug Administration Schedule; D005921:Glomerulonephritis / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology*; D019694:Hepatitis B, Chronic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000008:administration & dosage*; D008297:Male; D018894:Reverse Transcriptase Inhibitors / Q000008:administration & dosage*
D018894:Reverse Transcriptase Inhibitors; D019259:Lamivudine