title: Cyberknife radiosurgery for squamous cell carcinoma of vulva after prior pelvic radiation therapy.
abstract: Limited options exist for patients experiencing a local recurrence of vulvar malignancies after surgery and pelvic radiation. These recurrences often are associated with cancer-related skin desquamation and poor clinical outcomes. A new radiotherapeutic treatment modality for the previously irradiated patient is cyberknife radiosurgery, which uses a linear accelerator mounted on an industrial robotic arm to allow non-coplanar radiation therapy delivery with sub-millimeter precision. This study describes the first reported use of cyberknife radiosurgery for the treatment of recurrent vulvar cancer in three women.
authors.affiliation: Department of Radiation Oncology, University Hospitals of Cleveland Case Medical Center and Case Western Reserve University, Cleveland, OH 44106, USA. charles.kunos@UHhospitals.org
authors.forename: Charles
authors.initials: C
authors.lastname: Kunos
authors.forename: Vivian
authors.initials: V
authors.lastname: von Gruenigen
authors.forename: Steven
authors.initials: S
authors.lastname: Waggoner
authors.forename: James
authors.initials: J
authors.lastname: Brindle
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Zhang
authors.forename: Brenda
authors.initials: B
authors.lastname: Myers
authors.forename: Gary
authors.initials: G
authors.lastname: Funkhouser
authors.forename: Barry
authors.initials: B
authors.lastname: Wessels
authors.forename: Douglas
authors.initials: D
authors.lastname: Einstein
mesh_terms: D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D010315:Particle Accelerators; D010388:Pelvis / Q000528:radiation effects; D016634:Radiosurgery / Q000295:instrumentation* / Q000379:methods*; D011878:Radiotherapy / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012008:Recurrence; D012371:Robotics; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000532:radiotherapy* / Q000601:surgery*