Sweet's syndrome in association with common variable immunodeficiency.
Sweet's syndrome (SS), a rare reactive neutrophilic dermatosis, has been reported to occur in association with a variety of systemic disorders, categorized by von den Diesch into idiopathic, paraneoplastic, pregnancy and parainflammatory subgroups. The parainflammatory group has been well defined, and includes a wide spectrum of infectious triggers and disorders of immune dysregulation. To date, however, no cases of SS have been described in the context of common variable immunodeficiency (CVID). We report a case of paediatric-onset SS, previously reported as idiopathic, with a subsequent diagnosis of CVID.
O'Regan
G M
GM
Department of Dermatology, Beaumont Hospital, Dublin, Ireland.
Ho
W L
WL
Limaye
S
S
Keogan
M T
MT
Murphy
G M
GM
D000293:Adolescent; D000367:Age Factors; D017668:Age of Onset; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001987:Bronchiectasis / Q000150:complications* / Q000188:drug therapy; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D003622:Dapsone / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D016463:Sweet Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
D000890:Anti-Infective Agents; D003622:Dapsone