Fibroblasts act as co-conspirators for chemotherapy resistance.
Radisky
Derek C
DC
Mayo Clinic Cancer Center, Jacksonville, Florida 32224, USA. radisky.derek@mayo.edu
D000970:Antineoplastic Agents / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D002277:Carcinoma / Q000473:pathology; D016923:Cell Death / Q000187:drug effects; D045744:Cell Line, Tumor; D002468:Cell Physiological Phenomena / Q000187:drug effects*; D002945:Cisplatin / Q000627:therapeutic use; D018920:Coculture Techniques; D004351:Drug Resistance / Q000187:drug effects*; D005347:Fibroblasts / Q000378:metabolism*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008954:Models, Biological; D009336:Necrosis / Q000473:pathology; D017239:Paclitaxel / Q000627:therapeutic use; D015398:Signal Transduction
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel; D002945:Cisplatin