title: Total syntheses of a North methanocarba puromycin analog and its dinucleotide derivative.
abstract: North methanocarba Puromycin analog 5 and its di-nucleotide derivative 6 were synthesized from D-ribose in respectively 18 and 19 steps, in order to be tested for peptidyl transfer efficiency in ribosomes.
authors.affiliation: Laboratoire de Synthèse de Biomolécules, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (UMR 5246), Université Claude Bernard Lyon 1, 69622, Villeurbanne, France. benoit.michel@yahoo.fr
authors.forename: Benoît Y
authors.initials: BY
authors.lastname: Michel
authors.forename: Peter
authors.initials: P
authors.lastname: Strazewski
mesh_terms: D003562:Cytidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D011500:Protein Synthesis Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D011691:Puromycin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D011500:Protein Synthesis Inhibitors; D011691:Puromycin; D003562:Cytidine