Spontaneous prenatal ductal closure: postnatal diagnosis?
Prenatal ductal constriction and closure usually are related to maternal intake of prostaglandin receptor inhibitors during late gestation but may occur spontaneously. This report describes three live-born infants sharing echocardiographic features of spontaneous intrauterine ductal constriction, closure, or both, although only one had a prenatal diagnosis. Interestingly, in addition to severely hypertrophied right ventricles, all three had hyperechogenic tricuspid valve papillary muscles. Two also had mild ascending aorta dilation. These cases raise mechanistic questions because of intrauterine ductal occlusion, bright papillary muscles, and potential dilated ascending aortas.
Nygaard
Sissel Irene
SI
Department of Cardiology, Skejby University Hospital, Aarhus, Denmark. siyg@uus.no
Petersen
Olav Bjorn
OB
Garne
Ester
E
Sørensen
Keld Ejvind
KE
D001011:Aorta / Q000002:abnormalities / Q000000981:diagnostic imaging; D001018:Aortic Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D004374:Ductus Arteriosus, Patent / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D017380:Hypertrophy, Right Ventricular / Q000000981:diagnostic imaging* / Q000473:pathology; D007231:Infant, Newborn; D008297:Male; D010210:Papillary Muscles / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014261:Tricuspid Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging; D016216:Ultrasonography, Prenatal
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