title: Primary cutaneous mucormycosis (zygomycosis) caused by Apophysomyces elegans.
abstract: A 53 year-old male diabetic presented with a month-old, painful ulcer with necrotic margins over the right thigh. Wound debridement was done twice and the ulcer showed recurrent growth of a white, cottony filamentous structure. Cutaneous mucormycosis was suspected and confirmed by histopathology and a culture isolate of Apophysomyces elegans . The patient was treated with liposomal amphotericin-B and itraconazole followed by partial thickness skin grafting, and then discharged after being prescribed posaconazole syrup for three weeks. Regular follow-up was done and during the last visit after six months following discharge, the ulcer was found to have healed well with no recurrence of the fungus.
authors.affiliation: Department of Dermatology, Apollo Hospital, Hyderabad, India. drreddyis@gmail.com
authors.forename: I S
authors.initials: IS
authors.lastname: Reddy
authors.forename: N Raghupathi
authors.initials: NR
authors.lastname: Rao
authors.forename: V M
authors.initials: VM
authors.lastname: Shankar Reddy
authors.forename: Ratna
authors.initials: R
authors.lastname: Rao
mesh_terms: D000063:Accidents, Traffic; D000935:Antifungal Agents / Q000627:therapeutic use; D003646:Debridement; D003881:Dermatomycoses / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D048909:Diabetes Complications; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D009090:Mucorales / Q000302:isolation & purification; D009091:Mucormycosis / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D012008:Recurrence; D012867:Skin / Q000382:microbiology; D016038:Skin Transplantation; D013848:Thigh
chemical_list: D000935:Antifungal Agents