Involvement of the autonomic nervous system in motor adaptation: acceleration or error reduction?
In the last few decades motor adaptation was extensively studied observing the invariant features of reaching movements. In a parallel neurobehavioral line of research emotional learning was studied under the umbrella of the 'two-factor theory of learning'. In this study we explore the relation between motor learning and the autonomic response (heart rate, HR) of subjects performing point to point reaching movements holding a computer mouse. We consider two alternative outcomes: one is that autonomic response correlates with the learning rate and the second is that the autonomic response correlates with the residual error at the steady state. Eighteen subjects performed reaching movements under perturbed visual feedback demonstrating learning and after effects of learning. The hand movement as well as an Electrocardiogram signal were recorded throughout the training and carefully analyzed offline to extract the trial by trial error as well as the heart period. The results show clear correlation between the change in HR and the residual error but no correlation between the change in HR and the learning rate supporting the second alternative that the sensitivity to errors but not the learning rate correlates with the autonomic response. A control group of another seven subjects underwent the same experiment without the perturbed visual feedback. This control group showed no change in the HR. Further studies are required to validate this hypothesis and unravel the mechanism by which the autonomic response correlates with the residual motor error.
Edrei
Yinon
Y
Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel.
Mintz
Matti
M
Barnea
Ofer
O
Karniel
Amir
A
D000054:Acceleration; D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D001132:Arm / Q000502:physiology; D001341:Autonomic Nervous System / Q000502:physiology*; D005246:Feedback / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007858:Learning / Q000502:physiology*; D008297:Male; D009048:Motor Skills / Q000502:physiology; D009068:Movement / Q000502:physiology*; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology*; D013028:Space Perception / Q000502:physiology; D055815:Young Adult
Behav Brain Res. 1993 Dec 20;58(1-2):69-79
8136051
Brain Res. 2001 Apr 6;897(1-2):150-6
11282368
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5461-6
12704240
Exp Brain Res. 1981;42(2):223-7
7262217
PLoS Biol. 2006 Jun;4(6):e179
16700627
Exp Brain Res. 2000 Dec;135(4):474-82
11156311
Nat Neurosci. 2000 Nov;3 Suppl:1212-7
11127840
Nature. 1970 Feb 21;225(5234):752-3
5412785
J Neurophysiol. 2001 Aug;86(2):971-85
11495965
Trends Cogn Sci. 1998 Sep 1;2(9):338-47
21227230
Int J Psychophysiol. 2005 May;56(2):171-84
15804451
Hum Mov Sci. 2003 Feb;22(1):13-36
12623178
Nature. 2000 Jan 13;403(6766):192-5
10646603
Exp Brain Res. 2001 Dec;141(4):425-37
11810137
Curr Opin Neurobiol. 1999 Dec;9(6):718-27
10607637
J Neurosci. 1994 May;14(5 Pt 2):3208-24
8182467
Brain Res. 2001 Jan 19;889(1-2):112-7
11166694
Exp Brain Res. 1995;103(3):460-70
7789452
J Neurophysiol. 1994 Jul;72(1):299-313
7965013
Biol Cybern. 2003 Jul;89(1):10-21
12836029
J Neurosci. 2005 Sep 28;25(39):8948-53
16192385
Can J Physiol Pharmacol. 1996 Apr;74(4):401-17
8828887
J Comp Neurol. 1989 Apr 22;282(4):617-43
2723155
Behav Neurosci. 1992 Apr;106(2):262-73
1317182
J Neurophysiol. 2005 Jun;93(6):3200-13
15659526
J Neurosci. 2000 Dec 1;20(23):8916-24
11102502
Eur J Neurosci. 1998 Jan;10(1):86-94
9753116
J Neurosci. 1985 Jul;5(7):1688-703
4020415
J Neurosci. 2003 Oct 8;23(27):9032-45
14534237
Exp Brain Res. 2004 Mar;155(1):1-8
15064878
Prog Brain Res. 1976;44:317-37
1005722
Biol Cybern. 1999 Jul;81(1):39-60
10434390
J Neurosci. 1990 Jun;10(6):1906-11
2355257
J Exp Psychol. 1968 May;77(1):155-8
5663587
Nature. 2000 Oct 12;407(6805):742-7
11048720