The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations.
The novel pyrimidine (3-6) and purine (12-19) acyclic nucleoside analogues containing (Z) 4-amino or 4-aminohydrochloride-2-butenyl side chain (Fig.) were synthesized to evaluate their antiviral and cytostatic activity potency.
Wittine
Karlo
K
Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Benci
Kresimir
K
Pavelić
Sandra Kraljević
SK
Pavelić
Kresimir
K
Mintas
Mladen
M
D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D054697:Cytostatic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000998:Antiviral Agents; D054697:Cytostatic Agents; D011684:Purine Nucleosides; D011741:Pyrimidine Nucleosides