title: Flare-ups after endodontic treatment: a meta-analysis of literature.
abstract: The purpose of this study was to determine the frequency of flare-ups and to evaluate factors that affect it by using meta-analysis of results of previous studies. MEDLINE database was searched by using Entrez PubMed search engine and Medical Subject Headings (MeSH) search with EviDents Search Engine to identify the studies dealing with endodontic flare-up phenomenon. The search covered all articles published in dental journals in English from 1966-May 2007, and the relevancy of 119 selected articles was evaluated by reading their titles and abstracts, from which 54 were rejected as irrelevant and 65 were subjected to a suitability test. Six studies that met all the above mentioned criteria were included in the study. Average percentage of incidence of flare-ups for 982 patients was 8.4 (standard deviation +/-57). There were insufficient data to investigate the effect of the influencing factors.
authors.affiliation: Department of Endodontology, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. irgi@mcc.org.il
authors.forename: Igor
authors.initials: I
authors.lastname: Tsesis
authors.forename: Vadim
authors.initials: V
authors.lastname: Faivishevsky
authors.forename: Zvi
authors.initials: Z
authors.lastname: Fuss
authors.forename: Ofer
authors.initials: O
authors.lastname: Zukerman
mesh_terms: D000328:Adult; D000367:Age Factors; D003788:Dental Pulp Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D010483:Periapical Diseases / Q000209:etiology*; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D019233:Retreatment; D012307:Risk Factors; D012388:Root Canal Irrigants / Q000627:therapeutic use; D012390:Root Canal Therapy / Q000009:adverse effects; D012737:Sex Factors; D013997:Time Factors; D055815:Young Adult
chemical_list: D012388:Root Canal Irrigants