Case reports: fatal necrotizing fasciitis caused by Aeromonas sobria in two diabetic patients.
We report two rare cases of Aeromonas sobria necrotizing fasciitis with sepsis in patients with diabetes. In both cases, immediate fasciotomy was performed and appropriate empiric antimicrobial therapy and intensive care were administered. However, the two patients died on Day 2 and Day 11, respectively, after admission as a result of multiple organ failure. When patients present with a rapid onset of skin necrosis and progressive sepsis, an Aeromonas sobria infection or Vibrio infection should be considered in the differential diagnosis.
Tsai
Yao-Hung
YH
Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chia-Yi, Chang Gung University College of Medicine, No 6, West Sec, Chia-Pu Road, Putz City, Chia-Yi, 613, Taiwan, ROC. orma2244@adm.cgmh.org.tw
Huang
Kuo-Chin
KC
Huang
Tsung-Jen
TJ
Hsu
Robert Wen-Wei
RW
D000333:Aeromonas / Q000302:isolation & purification*; D000368:Aged; D000671:Amputation, Surgical; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003920:Diabetes Mellitus / Q000628:therapy*; D003937:Diagnosis, Differential; D019115:Fasciitis, Necrotizing / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D000071938:Fasciotomy; D017809:Fatal Outcome; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D018805:Sepsis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome
D000890:Anti-Infective Agents
Heart Lung. 2000 Jul-Aug;29(4):306-8
10900069
Surg Infect (Larchmt). 2007 Oct;8(5):523-8
17999586
FEMS Immunol Med Microbiol. 2002 Feb 18;32(3):237-42
11934569
Microbiol Immunol. 2002;46(6):383-90
12153115
J Foot Ankle Surg. 2003 Sep-Oct;42(5):305-8
14566724
J Clin Microbiol. 1981 Apr;13(4):769-77
6112237
J Med Microbiol. 1986 Jun;21(4):311-7
3723583
J Infect Dis. 1987 Mar;155(3):589-91
3805781
Pathology. 1988 Apr;20(2):188-90
3211597
Crit Rev Microbiol. 1989;16(4):253-86
2649316
J Trauma. 1990 Mar;30(3):324-7
2179571
Clin Infect Dis. 1993 Jan;16(1):69-74
8448321
Clin Infect Dis. 1993 Apr;16(4):574-9
8513068
Clin Infect Dis. 1993 Dec;17(6):1082-3
8110950
Clin Infect Dis. 1995 May;20(5):1298-304
7620014
Am J Gastroenterol. 1995 Dec;90(12):2234-5
8540527
Am J Gastroenterol. 1996 Jul;91(7):1475
8678032
Nephrol Dial Transplant. 1997 Aug;12(8):1730-4
9269663
Haematologica. 1997 Nov-Dec;82(6):692-4
9499669
Clin Infect Dis. 1998 Mar;26(3):651-8
9524839
J Formos Med Assoc. 1998 Jul;97(7):498-502
9700248
Clin Infect Dis. 1998 Aug;27(2):332-44
9709884
Pathol Int. 1999 Jun;49(6):541-6
10469397
Chang Gung Med J. 2004 Oct;27(10):766-9
15646300
J Immunol. 2006 Dec 15;177(12):8723-9
17142774
J Infect. 2007 Feb;54(2):151-8
16716402
J Bone Joint Surg Am. 2007 Mar;89(3):631-6
17332113
J Diabetes Complications. 2007 Jul-Aug;21(4):265-71
17616358
J Infect. 2000 May;40(3):267-73
10908022