title: Artificial beta-sheets: chemical models of beta-sheets.
abstract: Chemical models provide tools with which to simplify and study complicated biological systems. Forces and chemical processes that govern the structure, function, and interactions of a biomacromolecule can be explored with a simple, easy-to-study synthetic molecule. Chemical models of beta-sheet structures have helped to elucidate the factors influencing protein structures and functions. Chemical models that mimic beta-sheet quaternary structure and interactions are emerging as valuable tools with which to better understand and control protein recognition and protein aggregation.
authors.affiliation: Department of Chemistry, University of California, Irvine, Irvine, CA 92697-2025, USA.
authors.forename: Omid
authors.initials: O
authors.lastname: Khakshoor
authors.forename: James S
authors.initials: JS
authors.lastname: Nowick
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry; D006801:Humans; D008956:Models, Chemical; D010456:Peptides, Cyclic / Q000737:chemistry; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
chemical_list: D010456:Peptides, Cyclic; D011506:Proteins
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