Asymmetric Henry reaction catalyzed by bifunctional copper-based catalysts.
A new bifunctional copper-based catalytic system has been developed from readily available salen ligand 7 together with Cu(OAc)(2).H(2)O in situ for asymmetric nitro-aldol reactions between nitromethane and aldehydes, affording corresponding adducts with moderate to good yields and enantioselectivities.
Guo
Jun
J
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou, China.
Mao
Jincheng
J