title: Preliminary outcomes of primary phacoemulsification plus intraocular lens implantation for primary angle-closure glaucoma.
abstract: OBJECTIVE
  To evaluate effects and safety of primary phacoemulsification plus intraocular lens implantation for controlled chronic angle-closure glaucoma (CACG) or primary angle-closure (PAC).
  
  
  METHODS
  Prospective, non-randomized comparative trial.
  
  
  METHODS
  Two treatment groups were used. The IOL group included the use of phacoemulsification plus intraocular lens (IOL) implantation in 27 eyes. The LI group included treatment by laser iridotomy (LI) in 23 eyes. Intraocular pressure (IOP), numbers of anti-glaucoma medications, complications, and corneal endothelial cell counts were examined in each group.
  
  
  RESULTS
  In the IOL group, IOP was significantly reduced from a preoperative mean of 14.8 +/- 4.2 mmHg to a 6-month-postoperative mean of 10.8 +/- 1.6 mmHg (P < .05). However, in the LI group, mean preoperative IOP was 15.5 +/- 4.1 mmHg, and the 6-month-postoperative IOP was 14.7 +/- 4.7 mmHg (P = .76). In the IOL group, no patient used anti-glaucoma medications 6-month postoperatively, whereas in the LI group, mean number of anti-glaucoma medications was 0.2 +/- 0.4 (P < .05). There were no significant differences in preoperative and postoperative corneal endothelial cell counts between IOL and LI groups (P = .39).
  
  
  CONCLUSIONS
  Primary phacoemulsification plus intraocular lens implantation for controlled CACG or PAC seems to be a safe and effective method in reducing IOP. This procedure might become the first treatment of choice for controlled CACG or PAC with cataract.
authors.affiliation: Department of Ophthalmology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hata
authors.forename: Shinta
authors.initials: S
authors.lastname: Yamane
authors.forename: So
authors.initials: S
authors.lastname: Hata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shiota
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications; D002387:Cataract Extraction; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects; D011446:Prospective Studies; D012449:Safety; D016896:Treatment Outcome