title: Fibrosarcoma of the childhood mandible.
abstract: A case of low-grade intraosseous fibrosarcoma of the mandible in a 9-year-old girl is described. The patient underwent pre-surgical chemotherapy which was abandoned as unsuccessful after two cycles. Radical tumour resection and mandibular reconstruction with a titanium bar were performed 3 months after diagnosis. No adjuvant therapy was given and lymph node dissection was not performed. No signs of recurrences or metastasis have been observed after a follow up time of 3 years so far. This article is presented to document the rarity of fibrosarcomas in the jaws of children and emphasizes the possible changes in the appearance of radiological imaging under tumour progression.
authors.affiliation: Department of Cranio-Maxillo-Facial Surgery, University of Regensburg, Germany. martin.gosau@klinik.uni-regensburg.de
authors.forename: Martin
authors.initials: M
authors.lastname: Gosau
authors.forename: Florian G
authors.initials: FG
authors.lastname: Draenert
authors.forename: Wolfgang A
authors.initials: WA
authors.lastname: Winter
authors.forename: Jörg
authors.initials: J
authors.lastname: Mueller-Hoecker
authors.forename: Oliver
authors.initials: O
authors.lastname: Driemel
mesh_terms: D001707:Biopsy, Needle; D002648:Child; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D011862:Radiography, Panoramic; D018570:Risk Assessment; D013514:Surgical Procedures, Operative / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
references.citation: Oral Oncol. 1998 Jul;34(4):292-6
references.pmid: 9813725
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Oct;104(4):e26-9
references.pmid: 17689114
references.citation: Anticancer Res. 2000 Sep-Oct;20(5C):3735-41
references.pmid: 11268447
references.citation: Am J Surg. 1989 Oct;158(4):373-7
references.pmid: 2802044
references.citation: Med Oral Patol Oral Cir Bucal. 2006 May 01;11(3):E243-6
references.pmid: 16648761
references.citation: J Craniomaxillofac Surg. 2007 Jan;35(1):48-51
references.pmid: 17296310
references.citation: Clin Imaging. 2003 Jan-Feb;27(1):59-70
references.pmid: 12504325
references.citation: Int J Oral Maxillofac Surg. 2005 Jul;34(5):579-81
references.pmid: 16053882
references.citation: Head Neck. 1992 Jan-Feb;14(1):1-7
references.pmid: 1624288
references.citation: Clin Oral Investig. 2004 Jun;8(2):52-5
references.pmid: 15281217
references.citation: Cancer. 2000 May 1;88(9):2172-80
references.pmid: 10813731