The relationship between heart rate variability and epileptiform activity among children--a controlled study.
Autonomic symptoms frequently occur during epileptic seizures. Attention has been mainly devoted to cardiovascular changes. We studied the relationship between heart rate variability (HRV) and epileptiform activity in children with epilepsy.Simultaneous electroencephalograms and electrocardiograms were recorded in 36 children diagnosed with epilepsy and in 36 children with unrelated conditions who served as a comparison group. Heart rate variability was evaluated by time-domain analysis, before, after, and during an epileptiform event, a benign abnormal event and baseline activity.An age-related change in the HRV associated with an epileptiform event was noted in the study group but not in the comparison group. No other significant differences in HRV were noted between the two groups or between true and benign abnormal events.Age seems to be a significant covariate in the analysis of HRV in children with epilepsy. Epileptiform activity is not associated with a significant change in HRV in children.
Assaf
Nurit
N
Hannah Khoushy Child Development Center, Bnai Zion Medical Center, Haifa, Israel. uriassaf@013.net.il
Weller
Boaz
B
Deutsh-Castel
Tsofia
T
Cohen
Ayala
A
Tirosh
Emanuel
E
D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male