title: [A case of idiopathic pulmonary alveolar proteinosis with multiple localized ground-glass opacities].
abstract: A 58-year-old Japanese female consulted our staff with multiple localized ground-glass opacities in chest CT. She underwent video assisted thoracoscopic surgery for diagnosis. Histopathologic finding from surgery specimen in one of ground-glass opacities revealed bronchioloalveolar carcinoma. Six months later, we performed second video assisted thoracoscopic surgery, and histopathologic finding of all other ground-glass opacities revealed pulmonary alveolar proteinosis. Serum anti GM-CSF antibody elevated, and she was diagnosed as having idiopathic pulmonary alveolar proteinosis. A case of idiopathic pulmonary alveolar proteinosis presenting multiple localized ground-glass opacities is rare. And, differentiating ground-glass opacities of pulmonary alveolar proteinosis and bronchioloalveolar carcinoma by chest CT is difficult.
authors.affiliation: Department of Internal Medicine, Toyama Prefectural Central Hospital. tan@tch.pref.toyama.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Abo
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Touge
authors.forename: Hideki
authors.initials: H
authors.lastname: Shinnou
authors.forename: Hideki
authors.initials: H
authors.lastname: Miyazawa
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Noto
authors.forename: Akio
authors.initials: A
authors.lastname: Uchiyama
authors.forename: Atsuo
authors.initials: A
authors.lastname: Miwa
authors.forename: Shoetsu
authors.initials: S
authors.lastname: Shimura
authors.forename: Saburo
authors.initials: S
authors.lastname: Izumi
mesh_terms: D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008875:Middle Aged; D011649:Pulmonary Alveolar Proteinosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed