title: Comparison of health-related quality of life measures for chronic renal failure: quality of well-being scale, short-form-6D, and the kidney disease quality of life instrument.
abstract: BACKGROUND
  Studies have found that health-related quality of life (HRQOL) measurements with different conceptual bases yield widely varying results within the same study sample. Using data from a cohort of patients with chronic kidney failure, the purpose of this study was to compare the Quality of Well-Being Scale-Self-Administered (QWB-SA), the Short-Form-6D (SF-6D), and the Kidney Disease Component Summary (KDCS).
  
  
  METHODS
  Baseline data from a multi-site prospective observational study of 322 veterans receiving hemodialysis were analyzed. Descriptive statistics were calculated. Confirmatory factor analysis was conducted to determine how closely the three HRQOL tools reflected the same underlying construct.
  
  
  RESULTS
  Our confirmatory factor analysis offered strong evidence that the subscales of the QWB-SA, SF-6D, and 7-subscale KDCS measured more than one factor in this study sample. In the three-factor model, the SF-6D and 7-subscale KDCS correlated .911 (P < .05), indicating 83% of the variance in the 7-subscale KDCS was correlated with the SF-6D. However, a two-factor model, in which the highly correlated SF-6D and 7-subscale KDCS were combined, fit the data almost as well as the three-factor model.
  
  
  CONCLUSIONS
  The three HRQOL measures addressed different underlying HRQOL constructs in this sample. The QWB-SA was significantly different from the SF-6D and KDCS.
authors.affiliation: Center for Management of Chronic Complex Care, Edward Hines Jr. VA Hospital, P.O. Box 5000 (151H), Hines, IL, 60141, USA. Karen.Saban@va.gov
authors.forename: Karen L
authors.initials: KL
authors.lastname: Saban
authors.forename: Kevin T
authors.initials: KT
authors.lastname: Stroupe
authors.forename: Fred B
authors.initials: FB
authors.lastname: Bryant
authors.forename: Domenic J
authors.initials: DJ
authors.lastname: Reda
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Browning
authors.forename: Denise M
authors.initials: DM
authors.lastname: Hynes
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011446:Prospective Studies; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D006435:Renal Dialysis
references.citation: Gen Hosp Psychiatry. 2006 Jul-Aug;28(4):306-12
references.pmid: 16814629
references.citation: Nephrol Nurs J. 2006 May-Jun;33(3):285-92
references.pmid: 16859200
references.citation: Qual Life Res. 2005 Feb;14(1):207-19
references.pmid: 15789955
references.citation: Headache. 2000 Sep;40(8):662-71
references.pmid: 10971663
references.citation: Hosp Formul. 1993 May;28(5):486-90, 492, 497-8
references.pmid: 10125806
references.citation: BMJ. 2002 Jun 15;324(7351):1417
references.pmid: 12065262
references.citation: Int J Qual Health Care. 1998 Dec;10(6):509-20
references.pmid: 9928590
references.citation: Qual Life Res. 2005 Jun;14(5):1321-32
references.pmid: 16047507
references.citation: Am J Kidney Dis. 2006 Mar;47(3):455-61
references.pmid: 16490624
references.citation: Kidney Int. 2002 Jan;61(1):239-48
references.pmid: 11786106
references.citation: Health Qual Life Outcomes. 2006 Mar 25;4:20
references.pmid: 16563170
references.citation: Psychol Bull. 1990 Mar;107(2):238-46
references.pmid: 2320703
references.citation: Qual Life Res. 1999 Aug;8(5):447-59
references.pmid: 10474286
references.citation: Int J Audiol. 2005 Mar;44(3):157-63
references.pmid: 15916116
references.citation: Annu Rev Public Health. 1994;15:535-59
references.pmid: 8054098
references.citation: Eura Medicophys. 2006 Jun;42(2):113-9
references.pmid: 16767062
references.citation: Am J Kidney Dis. 2004 Nov;44(5 Suppl 2):54-60
references.pmid: 15486875
references.citation: Qual Life Res. 1994 Oct;3(5):329-38
references.pmid: 7841967
references.citation: Kidney Int. 2005 Dec;68(6):2801-8
references.pmid: 16316356
references.citation: Qual Life Res. 2004 Aug;13(6):1153-61
references.pmid: 15287281
references.citation: Value Health. 2004 Sep-Oct;7(5):602-9
references.pmid: 15367255
references.citation: Health Econ. 2004 Sep;13(9):873-84
references.pmid: 15362179
references.citation: Ann Rheum Dis. 2007 Jun;66(6):771-7
references.pmid: 17213254
references.citation: J Nerv Ment Dis. 2006 Nov;194(11):877-9
references.pmid: 17102715
references.citation: Med Decis Making. 1999 Apr-Jun;19(2):141-8
references.pmid: 10231076
references.citation: Health Serv Res. 1988 Jun;23(2):203-35
references.pmid: 3384669
references.citation: Appl Health Econ Health Policy. 2004;3(2):91-102
references.pmid: 15702946
references.citation: J Natl Cancer Inst Monogr. 2004;(33):78-101
references.pmid: 15504921
references.citation: Health Econ. 2003 Nov;12(11):975-81
references.pmid: 14601159
references.citation: Qual Life Res. 2005 May;14(4):971-80
references.pmid: 16041894
references.citation: J Psychosom Res. 2006 Nov;61(5):731-4
references.pmid: 17084154
references.citation: Qual Life Res. 2007 May;16(4):545-57
references.pmid: 17286199
references.citation: Eur J Health Econ. 2005 Sep;6(3):253-60
references.pmid: 15968563
references.citation: Clin Nephrol. 2006 Dec;66(6):440-6
references.pmid: 17176916
references.citation: Acad Emerg Med. 1999 Jan;6(1):54-66
references.pmid: 9928978
references.citation: Arch Phys Med Rehabil. 2006 May;87(5):680-7
references.pmid: 16635631
references.citation: J Clin Epidemiol. 1998 Nov;51(11):1115-28
references.pmid: 9817129
references.citation: Med Care. 1992 Jun;30(6):473-83
references.pmid: 1593914
references.citation: Am J Kidney Dis. 2003 Mar;41(3):605-15
references.pmid: 12612984
references.citation: Neurology. 2002 Jul 9;59(1):103-8
references.pmid: 12105315
references.citation: Clin J Am Soc Nephrol. 2008 Jan;3(1):111-6
references.pmid: 18178781
references.citation: Med Decis Making. 1997 Jan-Mar;17(1):1-9
references.pmid: 8994146
references.citation: J Health Econ. 2002 Mar;21(2):271-92
references.pmid: 11939242
references.citation: Qual Life Res. 2005 Jun;14(5):1333-44
references.pmid: 16047508
references.citation: Health Econ. 2005 Nov;14(11):1169-89
references.pmid: 15942981
references.citation: Int Urol Nephrol. 2004;36(2):263-7
references.pmid: 15368708
references.citation: Med Care. 2004 Sep;42(9):851-9
references.pmid: 15319610
references.citation: Kidney Int. 2005 Mar;67(3):1093-104
references.pmid: 15698450
references.citation: Health Econ. 2003 Dec;12(12):1061-7
references.pmid: 14673814
references.citation: Clin Nephrol. 2003 Nov;60(5):341-51
references.pmid: 14640240
references.citation: Qual Life Res. 2002 Aug;11(5):437-47
references.pmid: 12113391
references.citation: Psychol Bull. 1989 Sep;106(2):315-7
references.pmid: 2678203
references.citation: Pharmacoeconomics. 1998 Apr;13(4):411-20
references.pmid: 10178665
references.citation: Qual Life Res. 2005 Feb;14(1):179-90
references.pmid: 15789952
references.citation: Clin Transplant. 2008 Jul-Aug;22(4):405-10
references.pmid: 18363736