title: Gadobenate dimeglumine-enhanced magnetic resonance imaging of primary leiomyoma of the liver.
abstract: We report a case of histologically proven primary leiomyoma of the liver that was evaluated with multiphasic 64-section computed tomography (CT) and gadobenate dimeglumine-enhanced magnetic resonance (MR) imaging. This lesion showed vivid enhancement during the arterial phase with sustained enhancement during the hepatic venous and equilibrium phases. During the liver-specific MR imaging phase (150 minutes after contrast injection), the same lesion demonstrated lack of contrast retention, thus appearing hypointense compared with the background liver. Because of this latter finding, the patient underwent partial resection of the liver. In primary hepatic leiomyoma, the absence of contrast uptake during the liver-specific phase of gadobenate dimeglumine-enhanced MR imaging may be inappropriately interpreted as a sign of malignancy, thus leading to unnecessary, aggressive management of such lesions.
authors.affiliation: Department of Radiological Sciences, University of Rome Sapienza, Rome, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Marin
authors.forename: Carlo
authors.initials: C
authors.lastname: Catalano
authors.forename: Massimo
authors.initials: M
authors.lastname: Rossi
authors.forename: Antonino
authors.initials: A
authors.lastname: Guerrisi
authors.forename: Michele
authors.initials: M
authors.lastname: Di Martino
authors.forename: Pasquale
authors.initials: P
authors.lastname: Berloco
authors.forename: Roberto
authors.initials: R
authors.lastname: Passariello
mesh_terms: D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007889:Leiomyoma / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA