title: Case reports: fatal necrotizing fasciitis caused by Aeromonas sobria in two diabetic patients.
abstract: We report two rare cases of Aeromonas sobria necrotizing fasciitis with sepsis in patients with diabetes. In both cases, immediate fasciotomy was performed and appropriate empiric antimicrobial therapy and intensive care were administered. However, the two patients died on Day 2 and Day 11, respectively, after admission as a result of multiple organ failure. When patients present with a rapid onset of skin necrosis and progressive sepsis, an Aeromonas sobria infection or Vibrio infection should be considered in the differential diagnosis.
authors.affiliation: Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chia-Yi, Chang Gung University College of Medicine, No 6, West Sec, Chia-Pu Road, Putz City, Chia-Yi, 613, Taiwan, ROC. orma2244@adm.cgmh.org.tw
authors.forename: Yao-Hung
authors.initials: YH
authors.lastname: Tsai
authors.forename: Kuo-Chin
authors.initials: KC
authors.lastname: Huang
authors.forename: Tsung-Jen
authors.initials: TJ
authors.lastname: Huang
authors.forename: Robert Wen-Wei
authors.initials: RW
authors.lastname: Hsu
mesh_terms: D000333:Aeromonas / Q000302:isolation & purification*; D000368:Aged; D000671:Amputation, Surgical; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003920:Diabetes Mellitus / Q000628:therapy*; D003937:Diagnosis, Differential; D019115:Fasciitis, Necrotizing / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D000071938:Fasciotomy; D017809:Fatal Outcome; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D018805:Sepsis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents
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