Tuberous sclerosis complex: a case report.
Tuberous Sclerosis Complex (TSC) was first described in the late 1800s as a relative of neurofibromatosis, but it has since been identified as a discrete disorder. Patients with TSC typically present with facial adenomas, seizure disorder, and a developmental disability. The syndrome is caused by mutations in either chromosomes 9 or 16, both of which code for cell development and maturation. This case report describes the unique findings of TSC, and suggests areas for future study. By understanding the dental and medical implications of TSC, early intervention may vastly improve a patient's overall quality of life.
Wong
Allen
A
Hospital Dentistry Program, Department of Dental Practice, University of the Pacific Arthur, A. Dugoni School of Dentistry, San Francisco, California, USA. awong@pacific.edu
Subar
Paul
P
Itaya
Lisa
L
D000328:Adult; D017742:Dental Care for Chronically Ill; D003730:Dental Care for Persons with Disabilities; D005260:Female; D006801:Humans; D008310:Malocclusion / Q000150:complications*; D009062:Mouth Neoplasms / Q000209:etiology*; D014402:Tuberous Sclerosis / Q000150:complications* / Q000503:physiopathology