[Preliminary study of treating parotid gland malignant tumor with saving facial nerve (surgery associated with 125I seed implant brachytherapy)].
OBJECTIVE
To study the clinical effect of treating parotid gland malignant tumor with facial never-preserving surgery combined with 125I seed implant brachytherapy.


METHODS
Thirty-two patients with parotid gland malignancy underwent tumor and parotid gland excision while preserving facial never. According to treating plan system (TPS), 125I seeds were implanted into the target area during or after operation. The patients were followed up after operation and the local tumor control and facial nerve function were observed.


RESULTS
Tumor recurrence was not found in any patient treated after 12 to 44 months of follow up. All patients did not show obvious radiation-related complications. The facial never function of all patients was basically normal 6 months after operation.


CONCLUSIONS
For parotid gland malignant tumor, surgery combined with 125I seeds implant brachytherapy can save facial nerve function, and the short-term effects were satisfactory.
Zhanf
Jian-guo
JG
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China. rszhang@126.com
Zhang
Jie
J
Song
Tie-li
TL
Zheng
Lei
L
Cai
Zhi-gang
ZG
Yu
Guang-yan
GY
D000293:Adolescent; D000328:Adult; D000368:Aged; D001918:Brachytherapy; D005154:Facial Nerve / Q000473:pathology*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D016896:Treatment Outcome; D055815:Young Adult
D007457:Iodine Radioisotopes