title: CBESW: sequence alignment on the Playstation 3.
abstract: BACKGROUND
  The exponential growth of available biological data has caused bioinformatics to be rapidly moving towards a data-intensive, computational science. As a result, the computational power needed by bioinformatics applications is growing exponentially as well. The recent emergence of accelerator technologies has made it possible to achieve an excellent improvement in execution time for many bioinformatics applications, compared to current general-purpose platforms. In this paper, we demonstrate how the PlayStation 3, powered by the Cell Broadband Engine, can be used as a computational platform to accelerate the Smith-Waterman algorithm.
  
  
  RESULTS
  For large datasets, our implementation on the PlayStation 3 provides a significant improvement in running time compared to other implementations such as SSEARCH, Striped Smith-Waterman and CUDA. Our implementation achieves a peak performance of up to 3,646 MCUPS.
  
  
  CONCLUSIONS
  The results from our experiments demonstrate that the PlayStation 3 console can be used as an efficient low cost computational platform for high performance sequence alignment applications.
authors.affiliation: School of Computer Engineering, Nanyang Technological University, Singapore. adri0004@ntu.edu.sg
authors.forename: Adrianto
authors.initials: A
authors.lastname: Wirawan
authors.forename: Chee Keong
authors.initials: CK
authors.lastname: Kwoh
authors.forename: Nim Tri
authors.initials: NT
authors.lastname: Hieu
authors.forename: Bertil
authors.initials: B
authors.lastname: Schmidt
mesh_terms: D000465:Algorithms; D016415:Sequence Alignment; D017421:Sequence Analysis / Q000379:methods*; D012984:Software; D018910:Video Games
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