[The effect of hormonal bursectomy on the histological development of follicles in the embryonal bursa of Fabricius in the chicken].
Forty chick embryos were hormonally bursectomized by dipping the eggs in testosterone propionate on day 3 of incubation. On day 14, 15, 16 and 17 of incubation the chick embryos were sacrificed and bursae of Fabricius were examined histologically. Besides depletion of bursal follicles and polypoid overgrowth of bursal epithelium, invagination of epithelial buds into the mesenchymal layer failed to occur and budding of bursal follicles into the bursal lumen was observed. This budding of bursal follicles could be caused by an alteration in the subepithelial mesenchymal layer caused by the hormonal treatment.
Hoffmann-Fezer
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Veterinärpathologisches Institut der Justus-Liebig-Universität Giessen, W. Germany.