title: [Successful management of ruptured aortic arch aneurysm infected with methicillin-resistant Staphylococcus aureus].
abstract: A 64-year-old woman was admitted due to back pain and dyspnea. She was suffering from fever of unknown origin for a few weeks without aortic aneurysm by enhanced chest computed tomography (CT). Chest CT taken 1 month later revealed rupture of aortic arch aneurysm. Total arch replacement was performed with in situ grafting under selective cerebral perfusion combined with deep hypothermic circulatory arrest. Rifampicin (RFP) was sprinkled on the graft at operation and omentopexy was done 5 days after the 1st operation. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated on the culture of the aneurysmal wall, therefore, polymyxin B immobilized fiber with direct hemoperfusion (PMX-DHP) was also conducted with antibiotic therapy. Her clinical course after the 2nd operation was uneventful with no infective complication. We report a successful case of ruptured aneurysm of aortic arch infected with MRSA and review our strategy as one of feasible options without using homograft or preparative RFP-bonded vascular prosthesis.
authors.affiliation: Department of Cardiovascular Surgery, Kobe Red Cross Hospital, Kobe, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kawahira
authors.forename: T
authors.initials: T
authors.lastname: Tsukube
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
authors.forename: S
authors.initials: S
authors.lastname: Kozawa
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000785:Aneurysm, Infected / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery*; D001019:Aortic Rupture / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D016106:Methicillin Resistance; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus / Q000302:isolation & purification
chemical_list: D012293:Rifampin