The different sources of variation in inbreeding depression, heterosis and outbreeding depression in a metapopulation of Physa acuta.
Understanding how parental distance affects offspring fitness, i.e., the effects of inbreeding and outbreeding in natural populations, is a major goal in evolutionary biology. While inbreeding is often associated with fitness reduction (inbreeding depression), interpopulation outcrossing may have either positive (heterosis) or negative (outbreeding depression) effects. Within a metapopulation, all phenomena may occur with various intensities depending on the focal population (especially its effective size) and the trait studied. However, little is known about interpopulation variation at this scale. We here examine variation in inbreeding depression, heterosis, and outbreeding depression on life-history traits across a full-life cycle, within a metapopulation of the hermaphroditic snail Physa acuta. We show that all three phenomena can co-occur at this scale, although they are not always expressed on the same traits. A large variation in inbreeding depression, heterosis, and outbreeding depression is observed among local populations. We provide evidence that, as expected from theory, small and isolated populations enjoy higher heterosis upon outcrossing than do large, open populations. These results emphasize the need for an integrated theory accounting for the effects of both deleterious mutations and genetic incompatibilities within metapopulations and to take into account the variability of the focal population to understand the genetic consequences of inbreeding and outbreeding at this scale.
Escobar
Juan Sebastián
JS
Centre d'Ecologie Fonctionnelle et Evolutive UMR 5175, 34293 Montpellier, France.
Nicot
Antoine
A
David
Patrice
P
D000818:Animals; D001947:Breeding; D005819:Genetic Markers; D014644:Genetic Variation; D005828:Genetics, Population; D006823:Hybrid Vigor / Q000235:genetics*; D012908:Snails / Q000235:genetics*
D005819:Genetic Markers
Genet Res. 1999 Dec;74(3):329-40
10689809
Genetics. 2006 Feb;172(2):1337-47
16322514
Genetics. 1936 Mar;21(2):113-35
17246786
Heredity (Edinb). 2005 Dec;95(6):428-36
16175196
Evolution. 1991 May;45(3):622-629
28568822
Genet Res. 2002 Dec;80(3):197-204
12688658
Evolution. 2000 Apr;54(2):485-91
10937225
Genetica. 2003 Jan;117(1):3-16
12656568
Evolution. 1999 Jun;53(3):758-768
28565642
Evolution. 2002 Jan;56(1):131-42
11913658
Evolution. 2007 Nov;61(11):2655-70
17894808
Mol Ecol. 2007 Feb;16(3):463-75
17257106
Genet Res. 2000 Feb;75(1):75-81
10740923
J Theor Biol. 1966 Sep;12(1):12-45
6015424
Genetics. 1948 Sep;33(5):477-87
17247292
Oecologia. 1995 Sep;104(1):93-100
28306918
Genetics. 1963 Oct;48:1303-12
14071753
Evolution. 2001 Jun;55(6):1085-94
11475044
Heredity (Edinb). 1999 Sep;83 ( Pt 3):337-46
10504432
Genetics. 1931 Mar;16(2):97-159
17246615
Heredity (Edinb). 1999 Sep;83 ( Pt 3):260-70
10504423
Mol Ecol. 2006 May;15(6):1561-76
16629811
Heredity (Edinb). 2000 Mar;84 ( Pt 3):273-82
10762398
Genetics. 2001 Nov;159(3):1217-29
11729164
Mol Ecol. 2007 Jun;16(12):2474-87
17561907
Am J Bot. 1998 May;85(5):644
21684945
Evolution. 1989 Aug;43(5):1097-1109
28564159
Genetics. 2001 Aug;158(4):1737-53
11514459
Genetics. 1997 Apr;145(4):1219-28
9093870
Proc Natl Acad Sci U S A. 1937 Jun;23(6):307-20
16577780
Evolution. 1994 Jun;48(3):842-852
28568280
Evolution. 1994 Oct;48(5):1735-1741
28568424
Evolution. 2005 Jul;59(7):1389-99
16153025
Evolution. 2003 Dec;57(12):2678-87
14761049
Mol Ecol. 2004 Jul;13(7):2023-36
15189223
Evolution. 1990 Nov;44(7):1814-1822
28567806
Genet Res. 1999 Dec;74(3):237-44
10689801
Evolution. 2000 Aug;54(4):1157-72
11005285
Heredity (Edinb). 1999 Aug;83 ( Pt 2):103-9
10469197
Proc Biol Sci. 2007 Sep 22;274(1623):2357-64
17623641
Genetics. 1974 Aug;77(4):771-93
4213910
Evolution. 1999 Dec;53(6):1734-1743
28565456
Evol Bioinform Online. 2007 Feb 23;1:47-50
19325852
Heredity (Edinb). 2001 Aug;87(Pt 2):190-7
11703509
Trends Ecol Evol. 2004 Sep;19(9):489-96
16701312
Am J Bot. 1997 Dec;84(12):1685
21708572
Genet Res. 1999 Dec;74(3):215-21
10689799
Am Nat. 2000 Feb;155(2):154-167
10686158
Genetica. 1998;102-103(1-6):559-67
9720298
Heredity (Edinb). 2000 Apr;84 ( Pt 4):452-7
10849069
Evolution. 1999 Dec;53(6):1757-1768
28565458
Evolution. 1996 Feb;50(1):54-70
28568860
Genetics. 2003 Aug;164(4):1627-33
12930766
Proc Biol Sci. 2005 Jul 7;272(1570):1333-8
16006327
Genetics. 2003 Mar;163(3):955-72
12663535
Am J Bot. 2005 May;92(5):842-51
21652465
Genetics. 1993 Oct;135(2):367-74
8244001
Genetics. 2000 May;155(1):337-48
10790407