title: Computed tomography-guided brain biopsy for in vivo diagnosis of a cholesterinic granuloma in a horse.
abstract: METHODS
  An 8-year-old warmblood mare was evaluated following an acute onset of neurologic abnormalities.
  
  
  RESULTS
  Computed tomography of the head revealed large masses in both lateral ventricles, and a presumptive diagnosis of cholesterinic granuloma was made.
  
  
  RESULTS
  Freehand biopsy of the intracranial masses was performed under computed tomographic guidance, and histologic examination of biopsy specimens confirmed the diagnosis. No adverse effects associated with the brain biopsy procedure were encountered. Clinical signs resolved, and long-term follow-up did not reveal any recurrence of neurologic deficits. The horse was able to return to its previous level of training.
  
  
  CONCLUSIONS
  Findings suggested that computed tomographic-guided brain biopsy is feasible in horses and can be used to establish a diagnosis in horses with intracranial masses.
authors.affiliation: Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium.
authors.forename: Katleen
authors.initials: K
authors.lastname: Vanschandevijl
authors.forename: Ingrid
authors.initials: I
authors.lastname: Gielen
authors.forename: Heidi
authors.initials: H
authors.lastname: Nollet
authors.forename: Lieven
authors.initials: L
authors.lastname: Vlaminck
authors.forename: Piet
authors.initials: P
authors.lastname: Deprez
authors.forename: Henri
authors.initials: H
authors.lastname: van Bree
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D002781:Cholesteatoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D002784:Cholesterol / Q000378:metabolism; D002831:Choroid Plexus / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D015745:Granuloma, Foreign-Body / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D006736:Horses; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*
chemical_list: D002784:Cholesterol