title: Concentration of 68Ga via solvent extraction.
abstract: The metallic cation, (68)Ga (III) is suitable for complexation with chelators either naked or conjugated with biological macromolecules, however, such labeling procedure requires high chemical purity and concentrated solutions of (68)Ga (III), which cannot be sufficiently fulfilled by the presently available (68)Ge/(68)Ga generator eluate. A method to increase the concentration and purity of (68)Ga obtained from a commercial (68)Ge/(68)Ga generator has been developed. The (68)Ga eluate (1M HCl) is extracted in methyl ethyl ketone, which is evaporated and taken in a small volume of buffer.
authors.affiliation: Isotope Production Division, Pakistan Institute of Nuclear Science & Technology, P.O. Nilore, Islamabad, Pakistan.
authors.forename: Tanveer Hussain
authors.initials: TH
authors.lastname: Bokhari
authors.forename: A
authors.initials: A
authors.lastname: Mushtaq
authors.forename: Islam Ullah
authors.initials: IU
authors.lastname: Khan
mesh_terms: D002074:Butanones; D005857:Germanium / Q000302:isolation & purification*; D007553:Isotope Labeling / Q000379:methods*; D008722:Methods; D011868:Radioisotopes / Q000302:isolation & purification; D012997:Solvents
chemical_list: D002074:Butanones; D011868:Radioisotopes; D012997:Solvents; D005857:Germanium; C005222:methylethyl ketone