title: Decreasing traits of fecal immunoglobulin A in neonatal and weaning piglets.
abstract: The concentration of fecal secretory immunoglobulin A (sIgA) in neonate and weaning piglets was measured daily from 1 day after birth to 50 days of age. The concentration of fecal sIgA started from the level of 10(4) microg/g wet feces 1 day after birth and then increased to a maximal value of up to 10(5) microg/g within a few days of birth. The values constantly declined to between 10(1) and 10(2) microg/g for the next 10 days and were relatively constant until weaning. The level of sIgA in the feces remained very low until at least 50 days of age. The vulnerability of pre- or post-weaning piglets can be explained, at least in part, by this low level of sIgA in the intestine.
authors.affiliation: Laboratory of Animal Science, Kyoto Prefectural University, Shimogamo, Kyoto, Japan. k_ushida@kpu.ac.jp
authors.forename: Kazunari
authors.initials: K
authors.lastname: Ushida
authors.forename: Chiyoko
authors.initials: C
authors.lastname: Kameue
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsukahara
authors.forename: Kikuto
authors.initials: K
authors.lastname: Fukuta
authors.forename: Nobuo
authors.initials: N
authors.lastname: Nakanishi
mesh_terms: D000375:Aging / Q000187:drug effects / Q000276:immunology; D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005243:Feces / Q000737:chemistry*; D005260:Female; D007070:Immunoglobulin A / Q000378:metabolism*; D011247:Pregnancy; D013552:Swine / Q000254:growth & development / Q000276:immunology*; D014886:Weaning
chemical_list: D000900:Anti-Bacterial Agents; D007070:Immunoglobulin A