title: Treatment of diffuse large B-cell lymphoma of the liver with yttrium-90 microsphere embolization.
abstract: BACKGROUND
  A 41-year-old male with a 4-year history of chronic hepatitis C presented with a 1-month history of abdominal pain, fatigue, weight loss, and night sweats.
  
  
  METHODS
  Laboratory examinations, chest, abdomen, and pelvic CT scans, PET-CT scans, ultrasound-guided needle biopsies of liver lesions, bone-marrow biopsy, flow cytometry, and immunohistochemical staining for B-cell markers including CD20.
  
  
  METHODS
  Chemoresistant diffuse large B-cell lymphoma, with gradual loss of CD20 antigen expression.
  
  
  RESULTS
  Embolization of hepatic tumors using yttrium-90 microspheres (Therasphere, Theragenics Corporation, Buford, GA).
authors.affiliation: Division of Neoplastic Diseases and Related Disorders, Medical College of Wisconsin, Milwaukee, WI 53226, USA. tfenske@mcw.edu
authors.forename: Timothy S
authors.initials: TS
authors.lastname: Fenske
authors.forename: Heather
authors.initials: H
authors.lastname: Benjamin
authors.forename: Steven H
authors.initials: SH
authors.lastname: Kroft
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Hohenwalter
authors.forename: William S
authors.initials: WS
authors.lastname: Rilling
mesh_terms: D000328:Adult; D018951:Antigens, CD20 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy / Q000379:methods; D003937:Diagnosis, Differential; D004621:Embolization, Therapeutic / Q000379:methods*; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000532:radiotherapy*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry / Q000175:diagnosis* / Q000532:radiotherapy*; D008297:Male; D008863:Microspheres; D010166:Palliative Care; D015021:Yttrium Radioisotopes / Q000008:administration & dosage*
chemical_list: D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D015021:Yttrium Radioisotopes