Proteins with weakly funneled energy landscapes challenge the classical structure-function paradigm.
Papoian
Garegin A
GA
Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599-3290, USA. gpapoian@unc.edu
D055592:Biophysical Phenomena; D001703:Biophysics; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013816:Thermodynamics
D004798:Enzymes; D011506:Proteins
Acc Chem Res. 2005 Dec;38(12):923-31
16359164
J Mol Biol. 2005 Mar 4;346(4):1121-45
15701522
Biopolymers. 2003 Mar;68(3):333-49
12601793
Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10659-64
18664578
Nature. 2007 Dec 6;450(7171):913-6
18026087
Curr Opin Struct Biol. 2002 Feb;12(1):54-60
11839490
Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13877-82
18779576
Proteins. 2001 Jan 1;42(1):38-48
11093259
J Mol Biol. 2003 Oct 10;333(1):187-99
14516752
Science. 1995 Mar 17;267(5204):1619-20
7886447
J Mol Biol. 2006 Feb 3;355(5):893-7
16343531
Nat Struct Mol Biol. 2007 Dec;14(12):1202-6
17994104