Nonutility of repeat laboratory testing for detection of Clostridium difficile by use of PCR or enzyme immunoassay.
The diagnostic gains of repeat testing for Clostridium difficile by enzyme immunoassay and PCR (i.e., initial negative result followed by positive result) within a 7-day period were 1.9 and 1.7%, respectively. There is little value of repeat testing for C. difficile by enzyme immunoassay or PCR.
Aichinger
Elisabeth
E
Division of Clinical Microbiology, College of Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.
Schleck
Cathy D
CD
Harmsen
William S
WS
Nyre
Lisa M
LM
Patel
Robin
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016360:Clostridioides difficile / Q000302:isolation & purification*; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods
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