title: Are dental procedures an important risk factor for infective endocarditis? A case-crossover study.
abstract: Although infective endocarditis (IE) is often reported to develop following dental treatment, no published data have accurately defined the risk of IE from dental procedures. The purpose of this study was to examine whether dental procedures constitute significant risk factors for endocarditis. The study population was composed of 170 hospitalized patients with infective endocarditis. The frequency of dental procedures during the 3-month period immediately before admission was compared with the frequency of such procedures during earlier 3-month control periods (when no endocarditis developed), using the case-crossover design. Thirty-four out of 98 patients with available information (35%) had had 81 dental procedures during the 2 years before hospitalization, 12 (12%) of whom had had 14 procedures during the 3 months before admission. The number and types of dental procedures performed during this 3-month period were not statistically different from those carried out during any earlier 3-month period, which served as a control period. Dental procedures do not significantly increase the risk of IE.
authors.affiliation: Department of Oral Pathology and Oral Medicine, School of Dentistry, Tel Aviv University, Tel Aviv, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Porat Ben-Amy
authors.forename: M
authors.initials: M
authors.lastname: Littner
authors.forename: Y
authors.initials: Y
authors.lastname: Siegman-Igra
mesh_terms: D000368:Aged; D018592:Cross-Over Studies; D003729:Dental Care / Q000009:adverse effects*; D004696:Endocarditis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
references.citation: Lancet. 2004 Jan 10;363(9403):139-49
references.pmid: 14726169
references.citation: Am J Cardiol. 1984 Oct 1;54(7):797-801
references.pmid: 6486031
references.citation: Arch Intern Med. 1992 Sep;152(9):1869-73
references.pmid: 1520053
references.citation: Am J Epidemiol. 1991 Jan 15;133(2):144-53
references.pmid: 1985444
references.citation: N Engl J Med. 1997 Feb 13;336(7):453-8
references.pmid: 9017937
references.citation: Curr Infect Dis Rep. 2005 Jul;7(4):251-256
references.pmid: 15963325
references.citation: Cochrane Database Syst Rev. 2004;(2):CD003813
references.pmid: 15106220
references.citation: Heart. 2001 Jan;85(1):66-8
references.pmid: 11119466
references.citation: Eur Heart J. 1995 Dec;16(12):1968-74
references.pmid: 8682034
references.citation: Am J Med. 1984 Apr;76(4):711-7
references.pmid: 6711576
references.citation: Arch Intern Med. 1994 Jan 24;154(2):137-44
references.pmid: 8285808
references.citation: Annu Rev Public Health. 2000;21:193-221
references.pmid: 10884952
references.citation: Isr Med Assoc J. 2004 Dec;6(12):728-31
references.pmid: 15609883
references.citation: Ann Intern Med. 1998 Nov 15;129(10):761-9
references.pmid: 9841581
references.citation: Ann Intern Med. 1998 Nov 15;129(10):829-31
references.pmid: 9841589
references.citation: BMJ. 2008 Apr 5;336(7647):770-1
references.pmid: 18390528
references.citation: BMJ. 2005 Aug 20;331(7514):428
references.pmid: 16012176
references.citation: Neurology. 2004 Dec 14;63(11):2006-10
references.pmid: 15596741
references.citation: Circulation. 2007 Oct 9;116(15):1736-54
references.pmid: 17446442
references.citation: Lancet. 1992 Jan 18;339(8786):135-9
references.pmid: 1346008
references.citation: Yale J Biol Med. 1977 Jan-Feb;50(1):49-58
references.pmid: 848048
references.citation: JAMA. 1997 Jun 11;277(22):1794-801
references.pmid: 9178793
references.citation: Clin Infect Dis. 2000 Apr;30(4):633-8
references.pmid: 10770721
references.citation: JAMA. 1983 Nov 4;250(17):2318-22
references.pmid: 6632128
references.citation: Circulation. 1999 Jun 1;99(21):2737-41
references.pmid: 10351966