Primary osteogenic sarcoma of the breast: A case report.
BACKGROUND
Primary osteosarcoma of the breast is a rare malignant tumour. It is typically a poor prognosis tumour, which has some interesting features worthy of discussion. We report a case of primary osteosarcoma of the breast and summarise the previous medical literature to highlight several details of this unusual tumour.


METHODS
A 66-year-old Caucasian lady presented with painless lump in her right breast. Mammography showed features of fibroadenoma with calcification and fine needle aspiration cytology was reported as showing malignant cells (C5). Wide local excision was performed and histological features were consistent with primary osteosarcoma with predominance of osteoclastic activity. Subsequent completion mastectomy was performed because of suspicion of incomplete excision. She remains disease free 8 years from her initial surgery.
Khan
Shabuddin
S
Department of General Surgery, Blackpool Victoria Hospital, Blackpool Fylde and Wyre NHS Trust, Blackpool, FY2 8NR, UK. mr.ravi@bfwhospitals.nhs.uk.
Griffiths
Ewen A
EA
Shah
Nigam
N
Ravi
Srinivasan
S
Breast Cancer. 2005;12(1):52-6
15657524
Int J Radiat Oncol Biol Phys. 2000 Jan 15;46(2):383-90
10661345
Acta Cytol. 2007 May-Jun;51(3):443-50
17536552
Breast. 2003 Feb;12(1):72-4
14659358
Histol Histopathol. 2007 Apr;22(4):373-7
17290347
Br J Cancer. 2004 Jul 19;91(2):237-41
15187996
Geburtshilfe Frauenheilkd. 1993 Nov;53(11):811-3
8293949
Radiology. 2007 Mar;242(3):683-94
17325062
Am J Surg Pathol. 1998 Aug;22(8):925-33
9706972
World J Surg Oncol. 2006 Dec 11;4:90
17156481