title: Conjunctivolimbal autograft using a fibrin adhesive in pterygium surgery.
abstract: OBJECTIVE
  To evaluate the efficacy and safety of fibrin bioadhesive in conjunctivolimbal autograft surgery for primary pterygium.
  
  
  METHODS
  Thirty-six eyes in 34 patients were reviewed with nasal primary pterygium who were treated with pterygium excision with superior conjunctivolimbal transplantation with fibrin bioadhesive. Surgical durations were recorded and the patients were followed up on the first day after surgery and then at 1, 2, 4, 8 and 12 weeks postoperatively. The graft-recipient site attachments were examined and subjective symptoms of patients were recorded at every follow-up examinations.
  
  
  RESULTS
  The mean patient age was 57.9+/-10.1 (ranging from 33 to 83) years. The mean follow-up period was 22.05+/-5.78 weeks. The mean surgery time was 18.04+/-5.65 minutes. The subjective symptoms (pain, foreign body sensation, tearing and discomfort) disappeared in 23 of 36 eyes (64%) in one week after surgery, and all discomforts subsided within two weeks after surgery in all patients. The conjunctivolimbal autograft was correctly positioned and fixed in 34 of 36 eyes (94.4%) throughout the follow-up period. Graft dehiscence was seen in two eyes (5.6%), one eye was treated with remedial sutures, and the other eye showed a spontaneous healing without remedial sutures. Transient graft edema occurred in four eyes (11.2%) but subsided spontaneously within a month. There were no cases of pterygium regrowth or complications due to the fibrin bioadhesive.
  
  
  CONCLUSIONS
  The use of fibrin bioadhesive in conjunctivolimbal autograft surgery in primary pterygium simplifies surgical techniques, shorten surgical duration, and produce less postoperative subjective symptoms . Therefore, the fibrin bioadhesive is a safe and effective tool to attach conjunctivolimbal autograft in primary pterygium surgery.
authors.affiliation: Department of Ophthalmology, Cheil Eye Hospital, Daegu, Korea.
authors.forename: Hyun Ho
authors.initials: HH
authors.lastname: Kim
authors.forename: Hong Jae
authors.initials: HJ
authors.lastname: Mun
authors.forename: Young Jeung
authors.initials: YJ
authors.lastname: Park
authors.forename: Kyoo Won
authors.initials: KW
authors.lastname: Lee
authors.forename: Jae Pil
authors.initials: JP
authors.lastname: Shin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D016850:Limbus Corneae; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011625:Pterygium / Q000601:surgery*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014182:Transplantation, Autologous
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives
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