title: Surgical case of giant malignant mesenchymoma in the posterior mediastinum that recurred in the bilateral mediastinum.
abstract: Malignant mesenchymoma is a soft-tissue tumor arising preferentially in the extremities and the retroperitoneum. We report a case of primary malignant mesenchymoma of the left side of the posterior mediastinum with local recurrence on both sides of the mediastinum. A 24-year-old woman was admitted to our hospital complaining of cough. Chest X-ray showed a giant mass in two-thirds of the left lung field, and computed tomography of the chest revealed a lobulated large mass with a fat-density area and a calcified spot in the mediastinum and left pleural space. Magnetic resonance of the chest demonstrated a large, solid mass consisting mainly of areas with the same intensity as fatty tissue and partly of areas of heterogeneous moderate intensity. The tumor was resected completely through a left posterolateral thoracotomy. The pathologic diagnosis was malignant mesenchymoma: well-differentiated liposarcoma with osteocartilagenous differentiation. The patient had local recurrence in both sides of the mediastinum 3 years and 6 months after surgery, and the recurrent tumors were completely resected again.
authors.affiliation: Department of Biological Regulation and Regenerative Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan. kogeka-tanimura@nms.ac.jp
authors.forename: Shigeo
authors.initials: S
authors.lastname: Tanimura
authors.forename: Yuji
authors.initials: Y
authors.lastname: Saito
authors.forename: Kazuo
authors.initials: K
authors.lastname: Honma
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Koizumi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008637:Mesenchymoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D013902:Radiography, Thoracic; D019616:Thoracic Surgical Procedures; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome