title: Accumulation of perfluorinated compounds in captive Bengal tigers (Panthera tigris tigris) and African lions (Panthera leo Linnaeus) in China.
abstract: The accumulation of perfluorinated compounds (PFCs) in the sera of captive wildlife species Bengal tigers (Panthera tigris tigris) and African lions (Panthera leo Linnaeus) from Harbin Wildlife Park, Heilongjiang Province, in China were analyzed by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Perfluorooctanesulfonate (PFOS) was the predominant contaminant with a mean serum concentration of 1.18 ng mL(-1) in tigers and 2.69 ng mL(-1) in lions. Perfluorononanoic acid (PFNA) was the second most prevalent contaminant in both species. The composition profiles of the tested PFCs differed between tigers and lions, and the percentages of perfluorooctanoic acid (PFOA) were greater in lions than in tigers, indicating different exposures and/or metabolic capabilities between the two species. Assessments of the risk of PFC contamination to the two species were obtained by comparing measured concentrations to points of departure or toxicity reference values (TRVs). Results suggest no risk of PFOS exposure or toxicity for the two species.
authors.affiliation: Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, PR China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Li
authors.forename: Leo Wai Yin
authors.initials: LW
authors.lastname: Yeung
authors.forename: Sachi
authors.initials: S
authors.lastname: Taniyasu
authors.forename: Paul K S
authors.initials: PK
authors.lastname: Lam
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Yamashita
authors.forename: Muqi
authors.initials: M
authors.lastname: Xu
authors.forename: Jiayin
authors.initials: J
authors.lastname: Dai
mesh_terms: D000818:Animals; D000836:Animals, Zoo / Q000378:metabolism*; D002681:China; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000737:chemistry / Q000378:metabolism*; D005466:Fluorocarbons / Q000737:chemistry / Q000378:metabolism*; D008045:Lions / Q000378:metabolism*; D018570:Risk Assessment; D046010:Tigers / Q000378:metabolism*
chemical_list: D004785:Environmental Pollutants; D005466:Fluorocarbons