Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides.
Sepp-Lorenzino
L
L
RNA Therapeutics, Merck Research Laboratories, West Point, Pennsylvania, USA. laura_sepplorenzino@merck.com
Ruddy
Mk
M
D016503:Drug Delivery Systems; D015894:Genome, Human / Q000502:physiology*; D006801:Humans; D020319:Oligodeoxyribonucleotides, Antisense / Q000008:administration & dosage / Q000276:immunology / Q000627:therapeutic use*; D034741:RNA, Small Interfering / Q000008:administration & dosage / Q000627:therapeutic use*; D013678:Technology, Pharmaceutical / Q000379:methods / Q000639:trends*
D020319:Oligodeoxyribonucleotides, Antisense; D034741:RNA, Small Interfering