[Classification tree analysis in serous ovarian adenocarcinoma patients for prognostic factors associated with three-year survival probability].
OBJECTIVE
To analyze the prognostic factors associated with three-year survival outcome in patients with serous ovarian adenocarcinoma by classification tree.


METHODS
Retrospectively we analyzed 81 cases with serous ovarian adenocarcinoma who had 3-year clinical outcomes and were hospitalized in People's Hospital from Jan 1991 to Dec 2003 by classification and regression trees (CART) software. Establish the classification tree.


RESULTS
Among the factors that were associated with the 3-year survival rate, age was the most important factor, other factors in turn were International Federation of Gynecology and Obstetrics (FIGO) stage, lymphoid metastasis, residual size after operation, chemotherapy and pathologic grade. By substitution variable analysis, it was demonstrated that there was cross interaction between age and residual size as well as age and chemotherapy.


CONCLUSIONS
Age, FIGO stage, lymphoid metastasis, residual size after operation, chemotherapy and pathologic grade are important prognostic factors related with three-year survival probability of serous ovarian adenocarcinoma patients.
Zhu
Hong-Lan
HL
Department of Gynecologic Cancer Center, People's Hospital, Peking University, Beijing 100044, China.
Li
Yi
Y
Zhao
Yi-Ming
YM
Cui
Heng
H
Zhao
Yan
Y
Chang
Xiao-Hong
XH
Feng
Jie
J
Wei
Li-Hui
LH
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017024:Chemotherapy, Adjuvant / Q000379:methods; D018284:Cystadenocarcinoma, Serous / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D015233:Models, Statistical; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology*; D011379:Prognosis; D012044:Regression Analysis; D012307:Risk Factors; D016019:Survival Analysis; D055815:Young Adult