title: Anal fissure: a review.
abstract: Patients often present to general and colorectal clinics with symptoms of anal fissures and can even present acutely to hospital. Conservative remedies have healing rates of up to 85% and have largely replaced surgery as first-line management. This review highlights the cardinal points in the aetiology, pathogenesis and treatment of anal fissures.
authors.affiliation: Department of General and Colorectal Surgery, Lister Hospital, Stevenage SG1 4AB.
authors.forename: D
authors.initials: D
authors.lastname: Wray
authors.forename: S
authors.initials: S
authors.lastname: Ijaz
authors.forename: S
authors.initials: S
authors.lastname: Lidder
mesh_terms: D001003:Anal Canal / Q000601:surgery*; D001905:Botulinum Toxins / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004106:Dilatation / Q000379:methods; D005401:Fissure in Ano / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D005996:Nitroglycerin / Q000627:therapeutic use; D013524:Surgical Flaps
chemical_list: D002121:Calcium Channel Blockers; D001905:Botulinum Toxins; D005996:Nitroglycerin; D007548:Isosorbide Dinitrate