title: Primary Sjögren Syndrome with tumefactive central nervous system involvement.
abstract: Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The patient was treated with oral prednisone with good response. Large tumefactive brain lesions are a complication of pSS.
authors.affiliation: Department of Neurology, Hospital Universitari Arnau de Vilanova-IRBLleida, Lleida, Spain. jsanahuja@comll.cat
authors.forename: J
authors.initials: J
authors.lastname: Sanahuja
authors.forename: S
authors.initials: S
authors.lastname: Ordoñez-Palau
authors.forename: R
authors.initials: R
authors.lastname: Begué
authors.forename: L
authors.initials: L
authors.lastname: Brieva
authors.forename: D
authors.initials: D
authors.lastname: Boquet
mesh_terms: D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006104:Granuloma, Plasma Cell / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis*
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