[Disseminated fusariosis in a patient with acute lymphoblastic leukaemia].
Invasive mould infections are a major cause of infectious mortality in highly immunosuppressed patients. Incidence in this high risk group is 10-20% with a death rate in excess of 50%. Most invasive moulds are Aspergillus spp. We present a case of a 74-year-old woman with acute lymphoblastic leukaemia who developed a rare disseminated mould infection with Fusarium solani during induction chemotherapy. We present the case story and discuss the pathogenesis, clinical characteristics and treatment of invasive fusariosis.
Hermansen
Niels Emil Ulrich
NE
Haematologisk Klinik, Rigshospitalet, DK-2100 København Ø. hermansen@dadlnet.dk
Ralfkiaer
Elisabeth Methner
EM
Kjeldsen
Lars
L
D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005670:Fusarium / Q000302:isolation & purification; D006801:Humans; D016867:Immunocompromised Host; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology
D000935:Antifungal Agents