title: A 13-year-old girl with cold agglutinin syndrome caused by anti-i.
abstract: A 13-year-old girl with cold agglutinin syndrome caused by anti-i was serologically positive for Epstein-Barr virus. The anti-i had a high titer at 4 degrees C and high thermal amplitude (reacting up to 37 degrees C with both cord i RBCs and the patient's autologous RBCs). The patient's hemoglobin dropped to 48 g/L. The age of the patient, the severity of the hemolysis, and the antibody specificity were unusual features of cold agglutinin syndrome. Transfusions with adult (I) red blood cells were effective.
authors.affiliation: Department of Transfusion Medicine and Serology, Harbor UCLA Medical Center, Torrance, CA 90509-2910, USA. hmm_md@yahoo.com
authors.forename: Holli M
authors.initials: HM
authors.lastname: Mason
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Arndt
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology* / Q000628:therapy; D000918:Antibody Specificity; D001323:Autoantibodies / Q000276:immunology*; D003289:Convalescence; D003450:Cryoglobulins / Q000276:immunology; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000276:immunology; D004910:Erythrocyte Membrane / Q000276:immunology; D017707:Erythrocyte Transfusion; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006525:Hepatitis, Viral, Human / Q000209:etiology / Q000276:immunology; D006801:Humans; D007048:I Blood-Group System / Q000276:immunology*; D009177:Mycoplasma pneumoniae / Q000276:immunology; D011019:Pneumonia, Mycoplasma / Q000150:complications / Q000276:immunology
chemical_list: D001323:Autoantibodies; D003450:Cryoglobulins; D006454:Hemoglobins; D007048:I Blood-Group System; C029443:cold agglutinins