title: Massive hepatic hemangioendothelioma and consumptive hypothyroidism.
abstract: Hypothyroidism was diagnosed in an infant with massive hepatic hemangioendothelioma. Markedly elevated serum reverse-triiodothyronine levels confirmed consumptive hypothyroidism. Large doses of thyroxine were initially required to normalise TSH. Thyroxine was tapered as the tumor regressed and was discontinued at 16 months old. Thyroid function remains normal without treatment.
authors.affiliation: The Liggins Institute, The University ofAuckland, New Zealand. f.mouat@auckland.ac.nz
authors.forename: Frances
authors.initials: F
authors.lastname: Mouat
authors.forename: Helen M
authors.initials: HM
authors.lastname: Evans
authors.forename: Wayne S
authors.initials: WS
authors.lastname: Cutfield
authors.forename: Paul L
authors.initials: PL
authors.lastname: Hofman
authors.forename: Craig
authors.initials: C
authors.lastname: Jefferies
mesh_terms: D003409:Congenital Hypothyroidism / Q000150:complications*; D005260:Female; D006390:Hemangioendothelioma / Q000150:complications*; D006529:Hepatomegaly / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000150:complications*; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D013974:Thyroxine