Patency and Agile capsules.
Small bowel strictures can be missed by current diagnostic methods. The Patency capsule is a new non-endoscopic dissolvable capsule which has as an objective of checking the patency of digestive tract, in a non-invasive manner. The available clinical trials have demonstrated that the Patency capsule is a good tool for assessment of the functional patency of the small bowel, and it allows identification of those patients who can safely undergo a capsule endoscopy, despite clinical and radiographic evidence of small-bowel obstruction. Some cases of intestinal occlusion have been reported with the Patency capsule, four of them needed surgery. So, a new capsule with two timer plugs (Agile capsule) has been recently developed in order to minimize the risk of occlusion. This new device stars its dissolution process earlier (30 h after ingestion) and its two timer plugs have been designed to begin the disintegration even when the device is blocked in a tight stricture.
Caunedo-Alvarez
Angel
A
Gastroenterology Service, "Virgen Macarena" University Hospital, Avda. Dr. Fedriani, Seville 41071, Spain. acaunedoa@meditex.es
Romero-Vazquez
Javier
J
Herrerias-Gutierrez
Juan-M
JM
D053705:Capsule Endoscopes / Q000009:adverse effects; D002986:Clinical Trials as Topic; D003251:Constriction, Pathologic; D006801:Humans; D007415:Intestinal Obstruction / Q000175:diagnosis; D007421:Intestine, Small / Q000473:pathology
Endoscopy. 2005 Sep;37(9):801-7
16116529
Endoscopy. 2005 Oct;37(10):1065-7
16189792
Gastrointest Endosc. 2004 Jun;59(7):926-7
15173819
Gastrointest Endosc. 2004 Nov;60(5):822-7
15557969
Gut. 2004 Mar;53(3):472
14960546
Rev Esp Enferm Dig. 2004 Jan;96(1):10-21
14971993
Gut. 2003 Mar;52(3):390-2
12584221
Am J Gastroenterol. 2004 Nov;99(11):2171-7
15554999
Gastrointest Endosc. 2004 Mar;59(3):461
14997161
Endoscopy. 2005 Sep;37(9):793-800
16116528
Am J Gastroenterol. 2006 Oct;101(10):2218-22
16848804
Gastrointest Endosc. 2003 Mar;57(3):427-8
12612537
Nature. 2000 May 25;405(6785):417
10839527
Clin Gastroenterol Hepatol. 2004 Jan;2(1):31-40
15017630
Clin Gastroenterol Hepatol. 2005 Feb;3(2):133-41
15704047
Dig Liver Dis. 2006 May;38(5):326-30
16527556
Endoscopy. 2003 Aug;35(8):713
12929075
Endoscopy. 2003 Jul;35(7):564-8
12822090
Gastrointest Endosc. 2005 Nov;62(5):712-6; quiz 752, 754
16246685
Eur J Gastroenterol Hepatol. 2003 Apr;15(4):363-7
12655255
Gastrointest Endosc. 2006 Aug;64(2):283-7
16860090
Endoscopy. 2005 Feb;37(2):174-7
15692935
J Clin Gastroenterol. 2006 Sep;40(8):688-91
16940879
J Clin Gastroenterol. 2007 Jul;41(6):576-82
17577114
Gastroenterology. 2004 Mar;126(3):643-53
14988816
Endoscopy. 2005 Sep;37(9):808-15
16116530
J Clin Gastroenterol. 2003 Sep;37(3):270-1
12960730
Gastrointest Endosc. 2008 May;67(6):902-9
18355824