Analysis of fine-needle aspirate biopsies from solid tumors by laser scanning cytometry (LSC).
Both flow and image cytometry have routine, reliable methods for ploidy analysis, each with its dbacks. LSC offers a non-destructive and non-consumptive method of analysis that allows repeated sample analysis as well as storage for later re-evaluation. Owing to the extremely small sample requirement, specimens can be obtained through minimally invasive procedures such as fine-needle aspirate biopsies or simple swabs. Tumors located at sites unsuitable for routine biopsy can be analyzed even on an out-patient basis.
Gerstner
Andreas O H
AO
University of Leipzig, Leipzig, Germany.
Tàrnok
Attila
A
D044963:Biopsy, Fine-Needle; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007202:Indicators and Reagents; D047569:Laser Scanning Cytometry / Q000379:methods*; D009369:Neoplasms / Q000473:pathology*; D011003:Ploidies; D012996:Solutions
D007202:Indicators and Reagents; D012996:Solutions