Influence of intracoronary shunt on myocardial damage: a prospective randomized study.
OBJECTIVE
We aimed to evaluate whether surgical intracoronary shunt protects myocardium in patients with moderate left ventricular dysfunction (MLVD).


METHODS
Thirty-nine patients consisted the shunt group and 43 patients consisted the shuntless group. Troponin I, CK, and CK-MB were measured preoperatively, and at 6 and 24h postoperatively. Cardiac enzymes, rate of postoperative atrial fibrillation (AF) and third month ejection fraction (EF) were compared between the groups.


RESULTS
There were no significant differences between the groups for preoperative troponin I, CK, CK-MB, and postoperative CK levels (at 6 and 24h). Postoperative troponin I and CK-MB levels were significantly lower in the shunt group (p<0.001). Although preoperative EF of the patients were not significantly different between groups, the third month EF were significantly increased in both groups, and this increment was significantly higher in the shunt group than the shuntless group. One patient (2.3%) died in the shuntless group whereas there was no death in the shunt group.


CONCLUSIONS
Intracoronary shunt has protective effects on myocardium in patients with moderate left ventricular dysfunction.
Emmiler
Mustafa
M
Department of Cardiovascular Surgery, Faculty of Medicine Kocatepe University, Afyonkarahisar, Turkey. dremmiler@yahoo.com
Kocogullari
Cevdet Ugur
CU
Ela
Yuksel
Y
Cekirdekci
Ahmet
A
D000368:Aged; D000714:Anastomosis, Surgical / Q000295:instrumentation / Q000379:methods; D001281:Atrial Fibrillation / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods* / Q000401:mortality; D003331:Coronary Vessels / Q000601:surgery; D003402:Creatine Kinase / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D019210:Troponin I / Q000378:metabolism*; D018487:Ventricular Dysfunction, Left / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*
D019210:Troponin I; D003402:Creatine Kinase