Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual.
Gaedigk
Andrea
A
Section of Developmental Pharmacology and Experimental Therapeutics, Children's Mercy Hospital & Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA. agaedigk@cmh.edu
Frank
Dorothee
D
Fuhr
Uwe
U
D000328:Adult; D001711:Biotransformation; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism; D004252:DNA Mutational Analysis; D003915:Dextromethorphan / Q000493:pharmacokinetics / Q000652:urine; D006239:Haplotypes; D006801:Humans; D008297:Male; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D044465:White People / Q000235:genetics*
D003915:Dextromethorphan; D019389:Cytochrome P-450 CYP2D6
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