title: [A case of elderly non-small cell lung cancer effectively treated by combined chemotherapy of gemcitabine and S-1].
abstract: The patient was an 86-year-old female who suffered from advanced non-small cell-lung cancer (cT4N3M1, Stage IV). She was treated with combined chemotherapy of gemcitabine and S-1 as first-line therapy. This regimen was performed as a phase I trial for elderly patients with advanced non-small cell lung cancer. The treatment assessment was evaluated as partial response. No toxic events were observed due to this therapy, so she was treated as an outpatient. She was considered to have good quality of life.
authors.affiliation: Dept. of Medicine and Molecular Science, Gunma University Graduate School of Medicine.
authors.forename: Kyoichi
authors.initials: K
authors.lastname: Kaira
authors.forename: Noriaki
authors.initials: N
authors.lastname: Sunaga
authors.forename: Noriko
authors.initials: N
authors.lastname: Yanagitani
authors.forename: Hisao
authors.initials: H
authors.lastname: Imai
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Utsugi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Kawata
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hisada
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Shimizu
authors.forename: Takafumi
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Ishizuka
authors.forename: Masatomo
authors.initials: M
authors.lastname: Mori
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000188:drug therapy*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D010094:Oxonic Acid / Q000627:therapeutic use*; D049268:Positron-Emission Tomography; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D000093542:Gemcitabine
chemical_list: D004338:Drug Combinations; D003841:Deoxycytidine; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000093542:Gemcitabine