[Smoking-related interstitial lung diseases: findings at high-resolution CT].
OBJECTIVE
To describe the anatomic and radiologic characteristics common to smoking-related interstitial lung diseases use and to evaluate the association between smoking and these diseases.


METHODS
We reviewed the clinical histories of patients with suspected smoking-related interstitial lung diseases from 2001 to 2005 who underwent high-resolution computed tomography and had radiologic findings of desquamative interstitial pneumonia, respiratory bronchiolitis, histiocytosis X, or pulmonary fibrosis. We analyzed the presence of emphysema, ground glass, centrilobar nodules, cysts, honey combing, and overlap among these findings.


RESULTS
Fourteen patients were included. In desquamative interstitial pneumonia, the most common finding was ground glass (100%); in respiratory bronchiolitis, it was centrilobar nodules (100%); cysts were the most common finding in histiocytosis (85.7%) and honey combing was the most common finding in fibrosis (100%). Furthermore, over 75% of the patients had emphysema, which supported the relation with tobacco use. The patients with bronchiolitis also had signs common to the other three diseases (ground glass, honey combing, and cysts).


CONCLUSIONS
There is a relation between smoking and these interstitial diseases, as well as overlapping in their clinical and radiological manifestations.
Medina
R
R
Servicio de Radiodiagnóstico, Hospital Universitario Dr. Peset, Valencia, España. rosana.medina@hotmail.com
Domingo
M L
ML
Calvillo
P
P
Martínez
M
M
Vilar
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed