Long-term antireflux medication use following pediatric Nissen fundoplication.
OBJECTIVE
Nissen fundoplication decreases the use of antireflux medications.


METHODS
Retrospective cohort study using discharge abstract data and pharmacy data.


METHODS
Twelve regional Kaiser Permanente hospitals in southern California.


METHODS
Three hundred forty-two patients underwent Nissen fundoplication.


METHODS
Nissen fundoplication.


METHODS
Use of antireflux medications.


RESULTS
The number of patients requiring antireflux medications decreased from 233 patients (68.1%) before Nissen fundoplication to 197 (57.6%) after Nissen fundoplication. Of the 233 patients, 176 (75.6%) were restarted on antireflux medications within 1 year after Nissen fundoplication. Use of antireflux medication decreased in neurologically healthy patients but was unchanged in neurologically impaired children.


CONCLUSIONS
Use of antireflux medication decreased after Nissen fundoplication. Neurologically healthy children showed the biggest decrease in antireflux medication use after Nissen fundoplication.
Lee
Steven L
SL
Division of Pediatric Surgery, Kaiser Permanente, Los Angeles Medical Center, 4760 Sunset Blvd, Third Floor, Los Angeles, CA 90027, USA. slleemd@yahoo.com
Sydorak
Roman M
RM
Chiu
Vicki Y
VY
Hsu
Jin-Wen
JW
Applebaum
Harry
H
Haigh
Philip I
PI
D002648:Child; D002675:Child, Preschool; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000517:prevention & control* / Q000601:surgery; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D008297:Male; D054328:Proton Pump Inhibitors / Q000008:administration & dosage*
D054328:Proton Pump Inhibitors