[Localization and age relations of ocular aberrations].
BACKGROUND
The aim of this study was to analyze the distribution of total, corneal, and mainly internal human third- to sixth-order aberrations (HOA) and investigate possible correlations between wavefront errors and patient age.


METHODS
For this study 140 eyes of 140 subjects (age range 17-77 years) were measured three times each using Nidek Optical Path Difference scan. Mean value and standard deviation for each Zernike polynomial was computed for a 5-mm pupil diameter, and six different age groups were formed.


RESULTS
There was wide individual variation in the internal wavefront aberrations. The mean root-mean-square value for HOA was 0.4563 microm+/-0.296 microm. No positive correlation was found between Zernike polynomials and increasing age. In total spherical aberration however a significant difference was found between the 26-35-year and > or =56-year age groups (p=0.0002), as well as to internal and total coma (Z8) (p=0.0487 and p=0.0117, respectively).


CONCLUSIONS
The internal, corneal, and total wavefront aberrations varied widely among patients. Some significant differences were found between the age groups. No correlation between age and the internal, corneal, or total aberrations was found.
Goebels
S C
SC
International Vision Correction Research Centre (IVCRC), Universitäts-Augenklinik Heidelberg, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Deutschland.
Auffarth
G U
GU
Holzer
M P
MP
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003315:Cornea / Q000503:physiopathology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012029:Refraction, Ocular; D012030:Refractive Errors / Q000175:diagnosis* / Q000503:physiopathology; D018709:Statistics, Nonparametric
J Opt Soc Am A Opt Image Sci Vis. 2002 Jan;19(1):137-43
11778716
Ophthalmologe. 2004 Jun;101(6):631-45; quiz 646-7
15260018
J Refract Surg. 2002 May-Jun;18(3 Suppl):S385-8
12046890
Vision Res. 2002 Jun;42(13):1611-7
12079789
J Cataract Refract Surg. 2003 Aug;29(8):1514-21
12954298
Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3318-24
16877397
J Cataract Refract Surg. 2003 Aug;29(8):1487-95
12954294
Ophthalmologe. 2006 Jul;103(7):596-604
16733691
J Cataract Refract Surg. 2003 Oct;29(10):1896-903
14604708
J Cataract Refract Surg. 2006 Jan;32(1):33-44
16516776
J Refract Surg. 2006 Nov;22(9 Suppl):S1021-3
17444086
J Refract Surg. 2006 Nov;22(9):898-903
17124885
Am J Ophthalmol. 2004 Jun;137(6):988-92
15183781
J Refract Surg. 2004 May-Jun;20(3):243-7
15188901
Invest Ophthalmol Vis Sci. 1999 Jun;40(7):1351-5
10359316
J Cataract Refract Surg. 2005 Aug;31(8):1512-9
16129285
J Opt Soc Am A Opt Image Sci Vis. 2001 Aug;18(8):1793-803
11488483
J Opt Soc Am A Opt Image Sci Vis. 2000 Oct;17(10):1697-702
11028517
J Refract Surg. 2006 Nov;22(9 Suppl):S1037-40
17444090
Am J Ophthalmol. 2005 Feb;139(2):225-8
15733980
Am J Ophthalmol. 2004 Jul;138(1):143-6
15234298