title: Synthesis of cellulose-graft-poly(N,N-dimethylamino-2-ethyl methacrylate) copolymers via homogeneous ATRP and their aggregates in aqueous media.
abstract: Cellulose-graft-poly(N,N-dimethylamino-2-ethyl methacrylate) (cellulose-g-PDMAEMA) copolymers were prepared by homogeneous atom transfer radical polymerization (ATRP) under mild conditions. Cellulose macroinitiator was successfully synthesized by direct acylation of cellulose with 2-bromopropionyl bromide in a room temperature ionic liquid (RTIL), 1-allyl-3-methylimidazolium chloride. Copolymers were obtained via ATRP of N,N-dimethylamino-2-ethyl methacrylate (DMAEMA) with CuBr/pentamethyldiethylenetriamine (PMDETA) as catalyst and N,N-dimethylformamide (DMF) as solvent without homopolymer byproduct. The grafting copolymers were characterized by (1)H NMR, FT-IR, and TGA measurements. The results confirmed that PDMAEMA had been covalently bonded to cellulose backbone. Furthermore, the assemblies or aggregates formed by cellulose-g-PDMAEMA copolymers in water were studied at various concentrations, temperatures, and pH values by means of UV, DLS, TEM, and AFM. The results indicate that the copolymers had the pH- and temperature-responsive properties similar to the expected stimuli-responses by PDMAEMA. The synthetic strategy presented here could be employed in the preparation of other novel biomaterials from a variety of polysaccharides.
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, People's Republic of China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Sui
authors.forename: Jinying
authors.initials: J
authors.lastname: Yuan
authors.forename: Mi
authors.initials: M
authors.lastname: Zhou
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Haijun
authors.initials: H
authors.lastname: Yang
authors.forename: Weizhong
authors.initials: W
authors.lastname: Yuan
authors.forename: Yen
authors.initials: Y
authors.lastname: Wei
authors.forename: Caiyuan
authors.initials: C
authors.lastname: Pan
mesh_terms: D002482:Cellulose / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D008689:Methacrylates / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D008956:Models, Chemical; D009757:Nylons / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry; D012542:Scattering, Radiation; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013818:Thermogravimetry / Q000379:methods; D014867:Water / Q000737:chemistry
chemical_list: D008689:Methacrylates; D009757:Nylons; D011108:Polymers; D011134:Polysaccharides; D012997:Solvents; C407037:poly(2-(dimethylamino)ethyl methacrylate); D014867:Water; D002482:Cellulose