Evidence for the co-circulation of dengue virus type 3 genotypes III and V in the Northern region of Brazil during the 2002-2004 epidemics.
The reintroduction of dengue virus type 3 (DENV-3) in Brazil in 2000 and its subsequent spread throughout the country was associated with genotype III viruses, the only DENV-3 genotype isolated in Brazil prior to 2002. We report here the co-circulation of two different DENV-3 genotypes in patients living in the Northern region of Brazil during the 2002-2004 epidemics. Complete genomic sequences of viral RNA were determined from these epidemics, and viruses belonging to genotypes V (Southeast Asia/South Pacific) and III were identified. This recent co-circulation of different DENV-3 genotypes in South America may have implications for pathological and epidemiological dynamics.
Nogueira
Meri Bordignon
MB
Instituto Carlos Chagas, Curitiba, PR, Brasil.
Stella
Vanessa
V
Bordignon
Juliano
J
Batista
Weber Cheli
WC
Borba
Luana de
Ld
Silva
Luis Hildebrando Pereira da
LH
Hoffmann
Federico Guillermo
FG
Probst
Christian Macagnan
CM
Santos
Claudia Nunes Duarte dos
CN
D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology / Q000821:virology*; D003716:Dengue Virus / Q000145:classification / Q000235:genetics*; D004196:Disease Outbreaks; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
D012367:RNA, Viral