Computed tomography-guided brain biopsy for in vivo diagnosis of a cholesterinic granuloma in a horse.
METHODS
An 8-year-old warmblood mare was evaluated following an acute onset of neurologic abnormalities.


RESULTS
Computed tomography of the head revealed large masses in both lateral ventricles, and a presumptive diagnosis of cholesterinic granuloma was made.


RESULTS
Freehand biopsy of the intracranial masses was performed under computed tomographic guidance, and histologic examination of biopsy specimens confirmed the diagnosis. No adverse effects associated with the brain biopsy procedure were encountered. Clinical signs resolved, and long-term follow-up did not reveal any recurrence of neurologic deficits. The horse was able to return to its previous level of training.


CONCLUSIONS
Findings suggested that computed tomographic-guided brain biopsy is feasible in horses and can be used to establish a diagnosis in horses with intracranial masses.
Vanschandevijl
Katleen
K
Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium.
Gielen
Ingrid
I
Nollet
Heidi
H
Vlaminck
Lieven
L
Deprez
Piet
P
van Bree
Henri
H
D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D002781:Cholesteatoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D002784:Cholesterol / Q000378:metabolism; D002831:Choroid Plexus / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D015745:Granuloma, Foreign-Body / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D006736:Horses; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*
D002784:Cholesterol