title: [Systematic continuous sequence approach in diagnosing fetal deformity].
abstract: OBJECTIVE
  To explore the value of ultrasonographic evaluation in fetal deformity in prenatal diagnosis by a systematic continuous sequence approach (SCSA).
  
  
  METHODS
  Successive prenatal ultrasonographic evaluation was performed to monitor the whole anatomic structure,form, posture and movement of 16,685 fetuses during gestation aging 14 approximately 40(+3) weeks.
  
  
  RESULTS
  Satisfactory ultrasonic images were obtained in 16,627 fetuses using the SCSA (99.65%). Of them, 514 abnormal fetuses were confirmed after subsequent labor or induced labor and 498 abnormal fetuses were correctly diagnosed using SCSA during prenatal stage (96.89%). Whereas 16 fetuses missed recognition (3.11%). Its sensitivity, specificity, positive and negative predictive value of diagnosis on fetal deformity were 96.98%, 99.96%, 98.66%, and 99.90 %, respectively.
  
  
  CONCLUSIONS
  SCSA in prenatal ultrasonographic evaluation of the fetal structure and malformation is reliable and accurate.
authors.affiliation: Department of Gynecology and Obstetrics, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Qi-neng
authors.initials: QN
authors.lastname: Chen
authors.forename: Wei-she
authors.initials: WS
authors.lastname: Zhang
authors.forename: Jin-xiu
authors.initials: JX
authors.lastname: Tan
authors.forename: Rong
authors.initials: R
authors.lastname: Lu
authors.forename: Xin-hua
authors.initials: XH
authors.lastname: Wu
mesh_terms: D000328:Adult; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods