Menopause, the metabolic syndrome, and mind-body therapies.
Cardiovascular disease risk rises sharply with menopause, likely due to the coincident increase in insulin resistance and related atherogenic changes that together comprise the metabolic or insulin resistance syndrome, a cluster of metabolic and hemodynamic abnormalities strongly implicated in the pathogenesis and progression of cardiovascular disease. A growing body of research suggests that traditional mind-body practices such as yoga, tai chi, and qigong may offer safe and cost-effective strategies for reducing insulin resistance syndrome-related risk factors for cardiovascular disease in older populations, including postmenopausal women. Current evidence suggests that these practices may reduce insulin resistance and related physiological risk factors for cardiovascular disease; improve mood, well-being, and sleep; decrease sympathetic activation; and enhance cardiovagal function. However, additional rigorous studies are needed to confirm existing findings and to examine long-term effects on cardiovascular health.
Innes
Kim E
KE
Center for the Study of Complementary and Alternative Therapies, University of Virginia Health Systems, Charlottesville, VA 22908-0905, USA. kei6n@virginia.edu
Selfe
Terry Kit
TK
Taylor
Ann Gill
AG
D000368:Aged; D001945:Breathing Exercises; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D005260:Female; D015438:Health Behavior; D006266:Health Education; D006801:Humans; D008593:Menopause; D024821:Metabolic Syndrome / Q000150:complications / Q000517:prevention & control*; D008875:Middle Aged; D012648:Self Care / Q000379:methods*; D026302:Tai Ji; D016387:Women's Health; D015013:Yoga
J Clin Endocrinol Metab. 2003 Jun;88(6):2399-403
12788834
J Appl Physiol (1985). 2001 Jun;90(6):2033-40
11356762
Evid Based Complement Alternat Med. 2007 Dec;4(4):469-86
18227915
Indian J Med Res. 2005 May;121(5):683-90
15937373
J Affect Disord. 2000 Jan-Mar;57(1-3):255-9
10708840
Endocr Rev. 2003 Jun;24(3):278-301
12788800
Circulation. 2001 Jan 23;103(3):435-41
11157697
Diabetes Metab. 2003 Sep;29(4 Pt 2):6S19-27
14502097
Am J Chin Med. 2004;32(3):453-9
15344428
Ital Heart J. 2003 Jun;4(6):363-6
12898798
J Altern Complement Med. 2004 Feb;10(1):163-5
15025890
J Am Geriatr Soc. 2002 Apr;50(4):746-54
11982679
Taehan Kanho Hakhoe Chi. 2007 Mar;37(2):249-56
17435410
J Clin Endocrinol Metab. 1999 Jun;84(6):1862-6
10372676
Sports Med. 2002;32(4):217-24
11929351
J Altern Complement Med. 1997 Fall;3(3):291-5
9430331
J Intern Med. 2003 Jul;254(1):6-12
12823638
Cancer. 2004 May 15;100(10):2253-60
15139072
Rheum Dis Clin North Am. 2000 Feb;26(1):125-32, x
10680200
Metabolism. 2002 Dec;51(12):1573-7
12489070
Complement Ther Med. 2007 Sep;15(3):164-71
17709061
J Am Geriatr Soc. 2000 Dec;48(12):1553-9
11129742
J Am Geriatr Soc. 1996 May;44(5):489-97
8617895
J Tradit Chin Med. 1991 Jun;11(2):153-8
1861523
Indian J Physiol Pharmacol. 2001 Jan;45(1):37-53
11211570
Lancet. 1975 Jan 11;1(7898):62-4
46021
Arch Phys Med Rehabil. 2007 May;88(5):673-80
17466739
J Altern Complement Med. 2003 Aug;9(4):529-38
14499029
J Gerontol Nurs. 2007 Feb;33(2):17-23
17310659
J Am Geriatr Soc. 2002 Jun;50(6):1024-30
12110061
J Surg Res. 2003 Dec;115(2):325-44
14697301
Endocrinol Metab Clin North Am. 2004 Jun;33(2):417-29
15158527
J Am Geriatr Soc. 2007 Apr;55(4):603-15
17397441
J Am Geriatr Soc. 1999 Mar;47(3):277-84
10078888
Phys Med Rehabil Clin N Am. 2004 Nov;15(4):773-81, vi
15458751
Am J Cardiol. 1997 Sep 15;80(6):815-7
9315602
Fertil Steril. 2002 Jan;77(1):128-35
11779602
Med Sci Sports Exerc. 1991 Oct;23(10):1194-200
1758297
Acta Paedopsychiatr. 1992;55(2):115-20
1585802
J Adv Nurs. 1995 Sep;22(3):562-8
7499625
J Am Board Fam Pract. 2005 Nov-Dec;18(6):491-519
16322413
Med J Aust. 2003 Mar 17;178(6):272-6
12633484
Metabolism. 2004 Apr;53(4):495-9
15045698
Control Clin Trials. 1998 Apr;19(2):159-66
9551280
Hypertens Res. 2005 Dec;28(12):945-51
16671332
Hawaii Med J. 2001 Nov;60(11):286-7
11797492
Neurology. 2004 Jun 8;62(11):2058-64
15184614
Blood Press. 2000;9(2-3):71-82
10855728
Am J Obstet Gynecol. 1987 Jul;157(1):140-1
3300346
Metabolism. 2007 Mar;56(3):320-6
17292719
J Gerontol A Biol Sci Med Sci. 2006 Feb;61(2):184-9
16510864
Brain Behav Immun. 2003 Aug;17(4):233-7
12831824
Curr Hypertens Rep. 2001 Apr;3(2):100-6
11276389
Altern Ther Health Med. 2004 Mar-Apr;10(2):44-9
15055093
Diabetes Care. 1999 Oct;22(10):1688-93
10526736
Diabetes Care. 2002 Jan;25(1):241-2
11772923
Altern Ther Health Med. 1996 Jan;2(1):40-6
8795871
Am J Hypertens. 1996 Oct;9(10 Pt 1):1013-7
8896654
Age Ageing. 2006 Jul;35(4):388-93
16624847
Appl Psychophysiol Biofeedback. 2004 Dec;29(4):269-78
15707256
Gen Hosp Psychiatry. 1995 May;17(3):192-200
7649463
Int J Fertil Womens Med. 1997 Mar-Apr;42(2):94-100
9160219
Ann Behav Med. 2003 Oct;26(2):134-8
14534030
Prog Cardiovasc Dis. 2004 Jan-Feb;46(4):321-36
14961455
Am J Chin Med. 2006;34(5):741-7
17080541
Med Sci Sports Exerc. 2003 Dec;35(12):1972-6
14652490
Am J Cardiol. 1999 May 13;83(9B):25F-29F
10357572
Med Sci Monit. 2006 May;12(5):CR196-9
16641875
Int J Aging Hum Dev. 2005;60(2):95-126
15801385
Circulation. 1999 Apr 27;99(16):2192-217
10217662
Support Care Cancer. 2004 May;12(5):293-301
14991388
Diabet Med. 2003 Apr;20(4):255-68
12675638
J R Soc Med. 1993 May;86(5):254-8
8505745
J Altern Complement Med. 2003 Oct;9(5):747-54
14629852
Physiol Rev. 1995 Jul;75(3):473-86
7624391
Indian J Physiol Pharmacol. 2005 Jul-Sep;49(3):358-62
16440857
Complement Ther Clin Pract. 2007 May;13(2):78-84
17400142
Am J Chin Med. 1998;26(2):223-30
9799974
Headache. 2007 May;47(5):654-61
17501846
J Psychosom Res. 2002 Oct;53(4):883-90
12377298
J Gerontol A Biol Sci Med Sci. 2006 Nov;61(11):1177-80
17167159
Diabetologia. 1988 Dec;31(12):902-9
3071485
Circulation. 1993 Dec;88(6):2794-802
8252693
Acta Diabetol. 2003 Jun;40(2):85-90
12861406
Maturitas. 2000 Mar 31;34(3):275-81
10717494
Curr Hypertens Rep. 2003 Jun;5(3):241-6
12724057
J Affect Disord. 2005 Dec;89(1-3):13-24
16185770
Int Q Community Health Educ. 1996 Jan 1;16(4):333-9
20841054
Ann Intern Med. 1994 Jan 1;120(1):47-55
8250456
Indian J Physiol Pharmacol. 1992 Apr;36(2):105-8
1506070
J Aging Phys Act. 2006 Jul;14(3):241-53
17090803
Diabetes Care. 2002 Jul;25(7):1177-84
12087016
Arterioscler Thromb Vasc Biol. 1997 Aug;17(8):1490-5
9301625
Psychophysiology. 1989 May;26(3):270-80
2756076
Altern Ther Health Med. 1998 May;4(3):46-61
9581321
J Am Geriatr Soc. 2004 Jun;52(6):892-900
15161452
Arch Phys Med Rehabil. 2004 Jan;85(1):142-52
14970982
J Cardiopulm Rehabil. 2003 Mar-Apr;23(2):90-6
12668929
J Assoc Physicians India. 2000 Jul;48(7):687-94
11273502
Br Med Bull. 2001;60:153-71
11809624
Nurs J India. 1992 Feb;83(2):27-8
1437663
Integr Cancer Ther. 2007 Sep;6(3):242-50
17761637
Vital Health Stat 10. 2006 Sep;(230):1-140
17069199
Gynecol Obstet Invest. 2005;59(4):192-201
15735370
Am J Chin Med. 2004;32(1):141-50
15154293
Curr Hypertens Rep. 2002 Dec;4(6):477-82
12419178
Prev Med. 1995 Sep;24(5):509-17
8524727
Indian J Physiol Pharmacol. 2001 Jul;45(3):355-60
11881576
Circulation. 2000 Oct 10;102(15):1773-9
11023931
Arch Intern Med. 2004 Mar 8;164(5):493-501
15006825
J Holist Nurs. 2004 Dec;22(4):351-73
15486154
Am J Obstet Gynecol. 1992 Dec;167(6):1831-6
1471706
Diabetes Care. 2007 Mar;30(3):716-8
17327347
Altern Ther Health Med. 2006 Jan-Feb;12(1):40-7
16454146
J Clin Invest. 2004 Jan;113(1):25-7
14702105
Br J Sports Med. 2001 Jun;35(3):148-56
11375872
Am J Cardiol. 2002 Jun 20;89(12A):5E-10E; discussion 10E-11E
12084395
J Altern Complement Med. 2006 May;12(4):373-8
16722787
Rheumatology (Oxford). 2005 May;44(5):685-7
15741197
Circulation. 2002 Nov 19;106(21):2634-6
12438283
Acta Obstet Gynecol Scand. 1999 Apr;78(4):263-84
10203292
J Altern Complement Med. 2002 Dec;8(6):797-812
12614533
Diabet Med. 2005 Dec;22(12):1701-6
16401315
Am J Chin Med. 2006;34(6):949-57
17163584
Atherosclerosis. 2006 Jan;184(1):137-42
15913634
Prog Neuropsychopharmacol Biol Psychiatry. 2003 Jun;27(4):705-9
12787860
J Altern Complement Med. 1999 Aug;5(4):371-82
10471018
J Altern Complement Med. 2004 Apr;10(2):261-8
15165407
Med Clin North Am. 2004 Jan;88(1):63-82
14871051
Int J Clin Pharmacol Ther. 2003 Aug;41(8):346-53
12940591
Appl Nurs Res. 2002 Nov;15(4):235-42
12444582
Hypertension. 2003 Oct;42(4):657-63
12913055
Indian J Physiol Pharmacol. 2006 Jan-Mar;50(1):41-7
16850902
J Mol Cell Cardiol. 1999 Nov;31(11):2049-61
10591031
Pathophysiol Haemost Thromb. 2002 Sep-Dec;32(5-6):325-8
13679667
Postgrad Med J. 1996 Jun;72(848):349-51
8758013
Indian J Physiol Pharmacol. 2005 Oct-Dec;49(4):462-8
16579401
Health Promot Int. 2004 Mar;19(1):33-8
14976170
Eur J Cardiovasc Prev Rehabil. 2006 Feb;13(1):3-9
16449858
Indian J Med Sci. 1997 Apr;51(4):123-7
9355699
Curr Opin Pulm Med. 2002 Nov;8(6):502-5
12394157
Med Sci Monit. 2005 Dec;11(12):CR555-561
16319785
Med Sci Sports Exerc. 1995 May;27(5):765-75
7674883
Mt Sinai J Med. 2003 Mar;70(2):101-12
12634902
WMJ. 2006 Oct;105(7):42-6
17163086
BMC Complement Altern Med. 2001;1:8
11696251
Br Med J (Clin Res Ed). 1985 Apr 13;290(6475):1103-6
3921124
Am J Cardiol. 2003 Oct 15;92(8):901-6
14556863
Int J Neurosci. 2004 Jul;114(7):777-86
15204043
J Clin Hypertens (Greenwich). 2003 May-Jun;5(3):219-25
12826785
Maturitas. 2007 Jul 20;57(3):286-95
17336473
Cardiol Clin. 2002 May;20(2):249-63
12119799
Gynecol Obstet Invest. 2005;60(3):162-6
15980658
J Am Geriatr Soc. 1996 May;44(5):498-506
8617896
Int J Psychosom. 1994;41(1-4):46-52
7843867
Endocrinology. 2001 Sep;142(9):3964-73
11517175
Eur J Cardiovasc Prev Rehabil. 2005 Feb;12(1):5-11
15703500
Obes Res. 2003 Nov;11(11):1278-89
14627747
Dig Liver Dis. 2002 Sep;34 Suppl 2:S134-9
12408457
J Hum Hypertens. 2005 Sep;19(9):697-704
15905884
J Altern Complement Med. 1999 Aug;5(4):383-9
10471019
Eur J Pharmacol. 2003 Feb 28;463(1-3):235-72
12600714
Clin Physiol. 2000 May;20(3):173-6
10792409
Eur J Clin Invest. 1997 May;27(5):443-9
9179553
Basic Res Cardiol. 2000;95 Suppl 1:I77-83
11192358
Fam Pract. 2004 Feb;21(1):107-13
14760055
Am J Cardiol. 2002 Jun 20;89(12A):28E-34E; discussion 34E-35E
12084401
Int J Obes Relat Metab Disord. 2004 Dec;28(12):1594-9
15467773
Psychiatr Clin North Am. 2003 Sep;26(3):563-80
14563098
Am J Chin Med. 2003;31(3):489-97
12943180
J Epidemiol Community Health. 2004 Dec;58(12):1004-10
15547060
Holist Nurs Pract. 2005 Jul-Aug;19(4):173-80
16006832
Indian J Cancer. 1983 Nov-Dec;20(5):268-70
6392068
Cardiovasc Res. 2002 Apr;54(1):25-35
12062358
Indian J Physiol Pharmacol. 2000 Oct;44(4):392-400
11214493
J Natl Black Nurses Assoc. 2000 Jan;11(1):27-35
11854949
J Psychol. 2003 Sep;137(5):405-19
14629072
Clin Exp Pharmacol Physiol. 2006 Sep;33(9):883-6
16922826
Public Health Rep. 1985 Mar-Apr;100(2):158-71
3920714
Psychosom Med. 2002 May-Jun;64(3):418-35
12021416
Am J Manag Care. 2002 Dec;8(20 Suppl):S635-53; quiz S654-7
12510788
Women Health. 2000;30(4):61-76
10983610
Int J Neurosci. 2003 Dec;113(12):1691-701
14602541
J Psychosom Res. 1997 Aug;43(2):209-17
9278909
Harv Rev Psychiatry. 2001 Nov-Dec;9(6):280-93
11600487
Maturitas. 2001 Jul 25;39(1):39-42
11451619
J Clin Endocrinol Metab. 2003 Jun;88(6):2404-11
12788835
Altern Ther Health Med. 2007 Sep-Oct;13(5):44-51
17900042
Am J Cardiol. 2002 Jan 15;89(2):164-8
11792336
Scand J Soc Med Suppl. 1989;44:1-36
2683043
Curr Hypertens Rep. 2003 Jun;5(3):247-54
12724058
Gynecol Endocrinol. 1997 Oct;11(5):341-55
9385535
Int J Geriatr Psychiatry. 2003 May;18(5):441-9
12766922
J Assoc Physicians India. 1979 Dec;27(12):1055-8
398852
Circulation. 2002 Aug 20;106(8):939-44
12186797
Percept Mot Skills. 1992 Dec;75(3 Pt 2):1331-43
1484805
Curr Opin Investig Drugs. 2004 Sep;5(9):929-35
15503646
Circulation. 2001 Jan 2;103(1):32-7
11136682
J Am Geriatr Soc. 2000 Aug;48(8):952-60
10968301
J Intern Med. 2001 Dec;250(6):521-9
11902821
Clin Endocrinol (Oxf). 1999 Oct;51(4):387-94
10583303
CNS Spectr. 1999 Dec;4(12):34-47
18311106
Biol Psychiatry. 2003 Apr 15;53(8):754-60
12706959
Arch Intern Med. 2003 Feb 24;163(4):427-36
12588201
J Hypertens. 2007 Jan;25(1):241-6
17143197
Am J Chin Med. 1996;24(2):193-8
8874677
Nurse Pract Forum. 1998 Dec;9(4):243-55
10214227
Int J Geriatr Psychiatry. 2006 Sep;21(9):890-7
16955451
Control Clin Trials. 2000 Oct;21(5 Suppl):212S-7S
11018578
Biomed Pharmacother. 2002;56 Suppl 2:257s-265s
12653178
Korean J Intern Med. 2006 Jun;21(2):109-15
16913440
Exp Physiol. 2000 May;85(3):327-30
10825420