[Human embryonic stem cells within the context of international research activity].
Research involving pluripotent human embryonic stem cells (hESCs) is a rapidly growing field of science. Since hESCs originate from early human embryos, alternative methods for producing pluripotent cells have been developed. This article introduces some of those strategies and, in addition, covers international efforts to establish consistent international standards for cultivation, characterization and preservation of hESCs. Furthermore, global trends to form networks in the field of stem cell research as well as endeavors to harmonize ethical standards for hESC research are presented. Finally, potential applications of hESCs in the field of pharmacology/toxicology are discussed as well as recent results of animal studies using hESCs.
Wobus
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Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung, Gatersleben, BRD. wobusam@ipk-gatersleben.de
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D000818:Animals; D018929:Cell Culture Techniques / Q000592:standards; D002460:Cell Line; D004195:Disease Models, Animal; D033041:Embryo Research / Q000941:ethics* / Q000331:legislation & jurisprudence; D053595:Embryonic Stem Cells / Q000637:transplantation; D032984:Ethics, Research; D005858:Germany; D006801:Humans; D007391:International Cooperation / Q000331:legislation & jurisprudence*