title: Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes.
abstract: Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified in the Lactobacillus casei genome, expressed in Lactococcus lactis, and functionally characterized. Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch.
authors.affiliation: Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA.
authors.forename: Aymerick
authors.initials: A
authors.lastname: Eudes
authors.forename: Guus B
authors.initials: GB
authors.lastname: Erkens
authors.forename: Dirk J
authors.initials: DJ
authors.lastname: Slotboom
authors.forename: Dmitry A
authors.initials: DA
authors.lastname: Rodionov
authors.forename: Valeria
authors.initials: V
authors.lastname: Naponelli
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Hanson
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism; D058973:Folate Receptors, GPI-Anchored; D016680:Genome, Bacterial; D007780:Lacticaseibacillus casei / Q000235:genetics* / Q000378:metabolism; D013294:Lactococcus lactis / Q000235:genetics / Q000378:metabolism; D008969:Molecular Sequence Data; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D058973:Folate Receptors, GPI-Anchored; D011956:Receptors, Cell Surface; C026989:thiamine-binding protein
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