title: Recently published papers: Renal replacement therapy: which route and how much? Intracerebral haematomas: does the size matter? Beta blockers and steroids: will we ever know?
abstract: Femoral access for renal replacement therapy appears to have a similar infection rate to jugular access. High-intensity renal support does not seem to improve mortality or length of hospital stay. Acute kidney injury as defined by Acute Kidney Injury Network predicts increased hospital mortality. Recombinant factor VIIa reduces growth of volume of intracerebral haematoma but does not affect clinical outcome. Sustained released metoprolol reduces perioperative cardiac events in non-cardiac surgery but leads to more deaths and strokes. Steroids are probably not beneficial in either children with non-Haemophilus influenzae type b bacterial meningitis, or in prophylaxis of acute respiratory distress syndrome (ARDS), but could be beneficial in the treatment of ARDS.
authors.forename: Vlad
authors.initials: V
authors.lastname: Kushakovsky
authors.forename: Richard
authors.initials: R
authors.lastname: Venn
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D002986:Clinical Trials as Topic / Q000639:trends; D006407:Hematoma, Epidural, Cranial / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D011642:Publications / Q000639:trends*; D017582:Renal Replacement Therapy / Q000379:methods*; D013256:Steroids / Q000008:administration & dosage*
chemical_list: D000319:Adrenergic beta-Antagonists; D013256:Steroids
references.citation: Anesth Analg. 2008 Apr;106(4):1025-30
references.pmid: 18349169
references.citation: J Am Coll Cardiol. 2006 Sep 5;48(5):964-9
references.pmid: 16949487
references.citation: JAMA. 2008 May 28;299(20):2413-22
references.pmid: 18505951
references.citation: BMJ. 2008 May 3;336(7651):969-70
references.pmid: 18434378
references.citation: Lancet. 2008 May 31;371(9627):1839-47
references.pmid: 18479744
references.citation: BMJ. 2008 May 3;336(7651):1006-9
references.pmid: 18434379
references.citation: N Engl J Med. 2008 May 15;358(20):2127-37
references.pmid: 18480205
references.citation: N Engl J Med. 2005 Feb 24;352(8):777-85
references.pmid: 15728810
references.citation: N Engl J Med. 2008 Jul 3;359(1):7-20
references.pmid: 18492867
references.citation: Lancet. 2008 May 31;371(9627):1813-4
references.pmid: 18479743
references.citation: N Engl J Med. 2008 May 15;358(20):2174-6
references.pmid: 18480212
references.citation: Crit Care Med. 2007 Aug;35(8):1837-43; quiz 1852
references.pmid: 17581483
references.citation: JAMA. 2008 May 7;299(17):2048-55
references.pmid: 18460665