title: Total synthesis of Ciliatamides A-C: stereochemical revision and the natural product-guided synthesis of unnatural analogs.
abstract: The first total synthesis of Ciliatamides A-C was completed, leading to a revision of the reported stereochemistry from (S,S) to the (R,R) enantiomers. Due to the expedited route, a library of over 50 unnatural ciliatamide analogs was also prepared.
authors.affiliation: Department of Chemistry, Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, USA.
authors.forename: Jana A
authors.initials: JA
authors.lastname: Lewis
authors.forename: R Nathan
authors.initials: RN
authors.lastname: Daniels
authors.forename: Craig W
authors.initials: CW
authors.lastname: Lindsley
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D055666:Lipopeptides / Q000737:chemistry; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001688:Biological Products; D055666:Lipopeptides; D009842:Oligopeptides; C529041:ciliatamide A; C529042:ciliatamide B; C529043:ciliatamide C
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