title: Simulations of lesion detection using a combined phased array LHMI-technique.
abstract: Ultrasound based elasticity imaging techniques have been developed during the past decades. Some of these techniques are based on an internal radiation force stimulation in which a transient or dynamic radiation force is produced by using a single or dual-frequency sonication. In addition, sonication and data acquisition can be implemented using combined or separate transducers. In this simulation study of lesion detection using localized harmonic motion imaging (LHMI), we used a combined phased array designed for simultaneous thermal ablation and lesion detection. In the sonication mode, a focused single-frequency amplitude-modulated sonication is used to induce harmonic motion and in the tracking mode, some of the array elements are used for pulse-echo tracking of the induced displacements. The results showed that the size of the lesion affected the induced displacement around the sonication point. The displacement tracking simulations demonstrated that these changes in the displacement distributions can be detected using only a few of the array elements in the tracking mode but the exact size of the lesion can not be detected accurately. The simulations also showed that two lesions having the radius of 2.5mm can be distinguished if distance between these lesions is at least 2.5mm.
authors.affiliation: University of Kuopio, Department of Physics, Yliopistonranta 1F, FIN-70211 Kuopio, Finland. Janne.Heikkila@uku.fi
authors.forename: Janne
authors.initials: J
authors.lastname: Heikkilä
authors.forename: Kullervo
authors.initials: K
authors.lastname: Hynynen
mesh_terms: D003198:Computer Simulation; D054459:Elasticity Imaging Techniques / Q000379:methods*; D004867:Equipment Design; D005240:Feasibility Studies; D020342:Finite Element Analysis; D009068:Movement; D009369:Neoplasms / Q000000981:diagnostic imaging*; D014159:Transducers
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