Protein microarrays for diagnostic assays.
Protein microarray technology has enormous potential for in vitro diagnostics (IVD). Miniaturized parallelized immunoassays are perfectly suited to generating a maximum of diagnostically relevant information from minute amounts of sample whilst only requiring small amounts of reagent. Protein microarrays have become well-established research tools in basic and applied research and the first products are already on the market. This article reviews the current state of protein microarrays and discusses developments and future demands relating to protein arrays in their role as multiplexed immunoassays in the field of diagnostics.
Hartmann
Michael
M
School of Chemical Science and Engineering, Department of Analytical Chemistry, Royal Institute of Technology, 10044, Stockholm, Sweden.
Roeraade
Johan
J
Stoll
Dieter
D
Templin
Markus F
MF
Joos
Thomas O
TO
D001681:Biological Assay; D006801:Humans; D007118:Immunoassay; D040081:Protein Array Analysis; D011506:Proteins / Q000032:analysis*; D011933:Reagent Kits, Diagnostic
D011506:Proteins; D011933:Reagent Kits, Diagnostic