title: Three-component one-pot synthesis of 4,6-diarylpyrimidin- 2(1H)-ones under solvent-free conditions in the presence of sulfamic acid as a green and reusable catalyst.
abstract: A rapid and efficient one-pot method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones and related heterocycles is described. The condensation of acetophenone derivatives, aldehydes and urea in the presence of sulfamic acid was employed to synthesize a variety of pyrimidinones in moderate to excellent yields. The scope and limitations of this method are described.
authors.affiliation: Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran. mmh1331@yahoo.com
authors.forename: Majid M
authors.initials: MM
authors.lastname: Heravi
authors.forename: Leila
authors.initials: L
authors.lastname: Ranjbar
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Derikvand
authors.forename: Behnoush
authors.initials: B
authors.lastname: Alimadadi
mesh_terms: D002384:Catalysis; D003247:Conservation of Natural Resources; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D015394:Molecular Structure; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents; D013055:Spectrophotometry, Infrared; D013451:Sulfonic Acids
chemical_list: D011744:Pyrimidinones; D012997:Solvents; D013451:Sulfonic Acids; C005741:sulfamic acid