title: Typhilitis in the pediatric patient.
abstract: Cancer statistics in children are promising as mortality rates consistently decrease, reflecting newer chemotherapeutic agents and the evolution of hematopoietic stem cell transplant. Typhilitis or neutropenic enterocolitis is a potentially life-threatening complication of cancer treatment often found in immunocompromised children receiving vigorous chemotherapeutic regimens and noted in children post-stem-cell transplant. Recent literature suggests a relationship between typhilitis and other types of cancers and immunocompromised illness occurring in both children and adults. The pathogenesis of typhilitis is poorly understood, with limited evidence regarding incidence. Nursing care and assessment of children receiving oncologic treatment requires vigilance and immediate response to prevent and manage complications, especially gastrointestinally related typhilitis.
authors.affiliation: Children's Hospital at Sinai, Sinai Hospital of Baltimore, Maryland 21215, USA. chaut@lifebridgehealth.org
authors.forename: Cathy
authors.initials: C
authors.lastname: Haut
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy; D053706:Typhlitis / Q000150:complications / Q000451:nursing* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents