Exercise, fitness, and neurocognitive function in older adults: the "selective improvement" and "cardiovascular fitness" hypotheses.
BACKGROUND
Although basic research has uncovered biological mechanisms by which exercise could maintain and enhance adult brain health, experimental human studies with older adults have produced equivocal results.


OBJECTIVE
This randomized clinical trial aimed to investigate the hypotheses that (a) the effects of exercise training on the performance of neurocognitive tasks in older adults is selective, influencing mainly tasks with a substantial executive control component and (b) performance in neurocognitive tasks is related to cardiorespiratory fitness.


METHODS
Fifty-seven older adults (65-79 years) participated in aerobic or strength-and-flexibility exercise training for 10 months. Neurocognitive tasks were selected to reflect a range from little (e.g., simple reaction time) to substantial (i.e., Stroop Word-Color conflict) executive control.


RESULTS
Performance in tasks requiring little executive control was unaffected by participating in aerobic exercise. Improvements in Stroop Word-Color task performance were found only for the aerobic exercise group. Changes in aerobic fitness were unrelated to changes in neurocognitive function.


CONCLUSIONS
Aerobic exercise in older adults can have a beneficial effect on the performance of speeded tasks that rely heavily on executive control. Improvements in aerobic fitness do not appear to be a prerequisite for this beneficial effect.
Smiley-Oyen
Ann L
AL
Department of Kinesiology, Iowa State University, Ames, IA 50011, USA. asmiley@iastate.edu
Lowry
Kristin A
KA
Francois
Sara J
SJ
Kohut
Marian L
ML
Ekkekakis
Panteleimon
P
D000368:Aged; D003071:Cognition; D015444:Exercise / Q000523:psychology*; D005080:Exercise Test; D006801:Humans; D009483:Neuropsychological Tests; D010101:Oxygen Consumption; D010809:Physical Fitness; D011930:Reaction Time; D012119:Respiration