title: Medium-term results of surgical ventricular restoration with papillary muscle realignment: providing additional benefits in enlarged ischemic left ventricle.
abstract: In 2001, we described a new surgical technique of surgical ventricular restoration (SVR) in severe heart failure by papillary muscle re-alignment and volume reduction. This procedure has been offered in our institution to patients with severely impaired left ventricular function. Here we examine our mid-term results and also compare them with a similar cohort of patients who had coronary artery bypass grafting (CABG) only. Between 1998 and 2005, 30 patients underwent SVR by papillary muscle realignment with coronary artery revascularization at our institution. A subset of 20 patients had their left ventricular volume measured by echocardiogram and MRI scan, and a maximal cardiopulmonary exercise test was performed before and after the operation. An unselected consecutive cohort of patients with matching age, gender, and hemodynamic status who underwent CABG only without SVR was tested using the same protocol and the results were compared. We noticed that there was a significant advantage for patients who had additional SVR over patients who had CABG only. The observed improvement in those who had SVR may be due to reduced metabolic mismatch as a result of reduced wall tension and normalization of the apical twist of the left ventricle. We believe this would provide a form of surgical treatment for heart failure secondary to ischemic cardiomyopathy at a time of reduced donor organ availability for transplant.
authors.affiliation: Department of Cardiac Surgery, Yorkshire Heart Centre, Leeds General Infirmary, Leeds, UK.
authors.forename: R Unnikrishnan
authors.initials: RU
authors.lastname: Nair
authors.forename: Diane
authors.initials: D
authors.lastname: Barker
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kumar
authors.forename: Kayala
authors.initials: K
authors.lastname: Javengula
authors.forename: Lip Bun
authors.initials: LB
authors.lastname: Tan
mesh_terms: D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures / Q000379:methods*; D015331:Cohort Studies; D001026:Coronary Artery Bypass; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000601:surgery*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000601:surgery*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010210:Papillary Muscles / Q000601:surgery*; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000601:surgery*