title: Acanthamoeba keratitis presenting as a plaque.
abstract: OBJECTIVE
  To report a case of Acanthamoeba keratitis clinically presenting with a plaque-like lesion typical of fungal keratitis.
  
  
  METHODS
  A 55-year-old woman presented with a yellow plaque-like lesion on the cornea surrounded by an infiltrate. Smears and culture were taken. The plaque was removed and subjected to histopathological investigation.
  
  
  RESULTS
  Smear, culture, and histopathology results confirmed Acanthamoeba (cysts). The patient was treated with intensive topical medication. The infection resolved after 8 weeks of treatment.
  
  
  CONCLUSIONS
  Acanthamoeba infection of cornea may present as a plaque-like lesion. In addition to topical medication, plaque removal helps in early resolution of the infection.
authors.affiliation: Cornea & Anterior Segment Service, LV Prasad Eye Institute, Bhubaneswar, Orissa, India.
authors.forename: Srikant K
authors.initials: SK
authors.lastname: Sahu
authors.forename: Sujata
authors.initials: S
authors.lastname: Das
authors.forename: Savitri
authors.initials: S
authors.lastname: Sharma
authors.forename: Geeta K
authors.initials: GK
authors.lastname: Vemuganti
mesh_terms: D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D001285:Atropine / Q000008:administration & dosage / Q000627:therapeutic use; D001645:Biguanides / Q000008:administration & dosage / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use; D003315:Cornea / Q000473:pathology*; D003937:Diagnosis, Differential; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000175:diagnosis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009883:Ophthalmic Solutions
chemical_list: D001645:Biguanides; D009883:Ophthalmic Solutions; C031233:polihexanide; D002939:Ciprofloxacin; D001285:Atropine