title: Cortical spreading edema in persistent visual migraine aura.
abstract: We present imaging evidence of the spreading of cortical edema with reversibly restricted water diffusion from the left occipital to the temporoparietal cortex in persistent visual migraine aura in a 58-year-old man. The right-sided visual field defect lasting for 15 days was associated with discoupling of glucose metabolism and blood flow and the decreased apparent diffusion coefficient also suggested cytotoxic edema. At 8 weeks no signs were present, and magnetic resonance imaging became normal; therefore, long-lasting restricted cortical water diffusion, even if coupled with hypometabolism and edema, can be reversible in persistent visual migraine aura.
authors.affiliation: Semmelweis University, Department of Neurology, Budapest, Balassa, U. L, H-1083, Hungary.
authors.forename: Dániel
authors.initials: D
authors.lastname: Bereczki
authors.forename: József
authors.initials: J
authors.lastname: Kollár
authors.forename: Norbert
authors.initials: N
authors.lastname: Kozák
authors.forename: Kornél
authors.initials: K
authors.lastname: Viszokay
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Barta
authors.forename: Judit
authors.initials: J
authors.lastname: Sikula
authors.forename: Mária Tünde
authors.initials: MT
authors.lastname: Magyar
mesh_terms: D000293:Adolescent; D001929:Brain Edema / Q000209:etiology* / Q000473:pathology; D002540:Cerebral Cortex / Q000503:physiopathology; D013181:Cortical Spreading Depression; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D020325:Migraine with Aura / Q000150:complications* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods