title: Sister Joseph's nodule umbilical manifestation of intraperitoneal carcinomatosis.
abstract: An umbilical metastasis is universally referred to as a sister Joseph's nodule if it is caused by extensive intraabdominal neoplastic disease. The presence of an umbilical metastasis usually indicates advanced disease, with poor prognosis. We report on a 64-year old women with a umbilical nodule that was at first not recognised as a metastatic lesion, so the diagnosis and treatment were delayed. Knowledge of this eponym can help to avoid delay in diagnosis by alerting the clinician and prompting investigations with CT scan and a histological examination.
authors.affiliation: Department of Surgery, AZ Maria Middelares, Gent, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Durieux
authors.forename: E
authors.initials: E
authors.lastname: Muysoms
authors.forename: D
authors.initials: D
authors.lastname: Claeys
mesh_terms: D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007813:Laparotomy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014472:Umbilicus / Q000473:pathology*