[Characteristics of endogenous intoxication in children with Helicobacter pylori-associated gastroduodenal diseases].
Endogenous intoxication indices, such as the levels of medium-weight molecules and oligopeptides, albumin binding ability, and the blood activity of NADH-alcohol dehydrogenase, were studied in 326 children with chronic gastroduodenitis and duodenal ulcerative disease, including 252 and 74 children with and without Helicobacter pylori infection, respectively. High endogenous intoxication was detected in the presence of Helicobacter pylori. The paper shows it possible to use the level of medium-weight molecules and oligopeptides, toxicity index, the blood activity of NADH-alcohol dehydrogenase as biochemical markers of the negative impact of Helicobacter pylori.
Korkotashvili
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D000426:Alcohol Dehydrogenase / Q000378:metabolism; D001427:Bacterial Toxins / Q000097:blood; D015415:Biomarkers / Q000097:blood / Q000378:metabolism; D002648:Child; D004381:Duodenal Ulcer / Q000175:diagnosis* / Q000378:metabolism / Q000382:microbiology; D004382:Duodenitis / Q000175:diagnosis* / Q000378:metabolism / Q000382:microbiology; D005756:Gastritis / Q000175:diagnosis* / Q000378:metabolism / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D009243:NAD / Q000378:metabolism; D009842:Oligopeptides / Q000097:blood; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism
D001427:Bacterial Toxins; D015415:Biomarkers; D009842:Oligopeptides; D012709:Serum Albumin; D009243:NAD; D000426:Alcohol Dehydrogenase