title: [Clinical study on Shen Shuai Fang in treating chronic renal failure].
abstract: OBJECTIVE
  To explore the effect of Shen Shuai Fang in treating Chronic Renal Failure (CRF) of deficiency of spleen and kidney with turbid damp and blood stagnation symptom.
  
  
  METHODS
  125 patients with CRF of deficiency of spleen and kidney with turbid damp and blood stagnation symptom were randomly divided into two groups, 75 patients in treatment group were treated with Shen Shuai Fang adding western medicine and the other patients in control group were treated only with western medicine. We observed the effect and indexes change including renal function, Hb, proteinuria, lipid before and after treatment.
  
  
  RESULTS
  After six months' treatment, the general effective rate in treatment group was 77.33%, which was higher than that in control group obviously (44.00%, P < 0.01). So treatment group was obviously better than control group on decreasing proteinuria, improving renal function, increasing Hb, ameliorating lipid metabolism (P < 0.05 or P < 0.01).
  
  
  CONCLUSIONS
  Shen Shuai Fang is effective to treat CRF of deficiency of spleen and kidney with turbid damp and blood stagnation symptom.
authors.affiliation: The First Affiliated Hospital of Sun Yet-sen University, Guangzhou 510080, China.
authors.forename: Xin-Lin
authors.initials: XL
authors.lastname: Wu
authors.forename: Zhi-Jian
authors.initials: ZJ
authors.lastname: Li
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Qin-Xing
authors.initials: QX
authors.lastname: Ao
authors.forename: Yuan-Wen
authors.initials: YW
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy* / Q000473:pathology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D017257:Ramipril / Q000627:therapeutic use; D016896:Treatment Outcome; D016710:Yin Deficiency / Q000188:drug therapy; D055815:Young Adult
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D017257:Ramipril