Brain scintigraphy with 99mTc-tetrofosmin for the differential diagnosis of a posterior fossa tumor.
A 60-year-old woman harbouring a tumour in the cerebellum. Anatomic brain imaging by computed tomography and magnetic resonance imaging were not conclusive of the lesion's nature. Imaging by (99m)Tc-tetrofosmin single-photon emission tomography (SPET) showed increased radiotracer accumulation in the lesion, indicating a vascular supply, membrane permeability and cellular metabolic activity, which is suggested to facilitate tracer uptake by lesions located in the posterior fossa. The patient underwent surgery and haemangioblastoma was confirmed by histology. Differential diagnosis is discussed. (99m)Tc-tetrofosmin scintiscan contributed to diagnostic information.
Alexiou
George A
GA
Department of Neurosurgery, University of Ioannina, School of Medicine, Ioannina, Greece. alexiougrg@yahoo.gr
Tsiouris
Spyridon
S
Voulgaris
Spyridon
S
Doukas
Mihalis
M
Goussia
Ann
A
Kyritsis
Athanasios P
AP
Polyzoidis
Konstantinos S
KS
Fotopoulos
Andreas D
AD
D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging*; D002531:Cerebellum / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D018325:Hemangioblastoma / Q000000981:diagnostic imaging*; D006801:Humans; D015192:Infratentorial Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin