title: Focal myocardial uptake in a patient with carcinoid tumor by indium-111-pentetreotide on SPECT/CT.
abstract: We present a case of a 44 year old man with flushing, diarrhea and markedly elevated 24 hour urinary 5-HIAA level, who was referred for an indium-111 pentetreotide study, after the excision of a carcinoid tumor in the terminal ileum. Scan findings revealed focal uptake in the myocardium and liver, suspicious for metastases. Subsequent transthoracic echocardiogram failed to demonstrate a cardiac lesion. Previously, our group has unequivocally demonstrated the usefulness of software fusion of SPECT and CT imaging in the evaluation of a carcinoid metastasizing to the myocardium. This case illustrates that hardware SPECT/CT fusion imaging utilizing indium-111 pentetreotide to evaluate metastatic carcinoid tumors can be useful. In addition, the echocardiogram can yield false negative results, because of a smaller lesion size and the influence of an operator-dependent factor.
authors.affiliation: Nuclear Medicine Service. Department of Radiology. Memorial Sloan-Kettering Cancer Center. New York. NY. USA. smahmood@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Mahmood
authors.forename: S R
authors.initials: SR
authors.lastname: Martínez de Llano
authors.forename: R K
authors.initials: RK
authors.lastname: Grewal
mesh_terms: D000328:Adult; D002275:Carcinoid Heart Disease / Q000000981:diagnostic imaging*; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging*; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D011877:Radionuclide Imaging; D013004:Somatostatin / Q000031:analogs & derivatives*
chemical_list: D007205:Indium Radioisotopes; D013004:Somatostatin; C081788:pentetreotide