Probing meiotic recombination decisions.
Meiotic recombination promotes genetic variation by mixing parental alleles. Two recent studies, one in this issue of Developmental Cell, have applied microarray-based methods that allow analysis of nearly all of the recombination events occurring in a single meiosis. These data provide insights into the molecular "decisions" that control the outcome of the recombination process.
Roig
Ignasi
I
Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Keeney
Scott
S
Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address: s-keeney@ski.mskcc.org.
D004271:DNA, Fungal / Q000235:genetics; D008540:Meiosis; D046228:Microarray Analysis; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism
D004271:DNA, Fungal; D029701:Saccharomyces cerevisiae Proteins