Cardiac resynchronization therapy and valvular cardiomyopathy after corrective surgery.
Cardiac resynchronization therapy (CRT) has been shown to have clinical benefits in certain groups of patients with advanced heart failure (HF). However, patients with valvular cardiomyopathy are underrepresented in randomized clinical studies. The aim of this study was to assess the medium-term (i.e., at 6 months) effects of CRT in patients with HF exclusively due to valvular disease. The study included 40 consecutive patients who underwent CRT device implantation. At 6 months, there were improvements in functional class, left ventricular remodeling, and intraventricular dyssynchrony parameters in treated patients. In this particular subgroup of patients, the benefits of CRT were similar to those observed in patients with HF due to other etiologies.
Macías
Alfonso
A
Departamento de Cardiología y Cirugía Cardiovascular, Clínica Universitaria de Navarra, Pamplona, Navarra, Spain.
Gavira
Juan J
JJ
Castaño
Sara
S
Moreno
José
J
Alegría
Eduardo
E
García-Bolao
Ignacio
I
D000368:Aged; D002304:Cardiac Pacing, Artificial; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000628:therapy*; D006349:Heart Valve Diseases / Q000150:complications*; D006801:Humans; D008297:Male