title: New secoiridoid glycosides from the roots of Picrorhiza scrophulariiflora.
abstract: Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyses and comparisons with data from related compounds. A pilot pharmacological study showed that picrogentiosides A (1) and B (2) have an immunomodulatory effect in vitro.
authors.affiliation: College of Chemistry, Jilin University, Changchun 130062, P.R. China. wdc9928@jluhp.edu.cn
authors.forename: Lian-Chun
authors.initials: LC
authors.lastname: Zou
authors.forename: Tong-Fei
authors.initials: TF
authors.lastname: Zhu
authors.forename: Hua
authors.initials: H
authors.lastname: Xiang
authors.forename: Lu
authors.initials: L
authors.lastname: Yu
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Yan
authors.forename: Shu-Cai
authors.initials: SC
authors.lastname: Gan
authors.forename: Da-Cheng
authors.initials: DC
authors.lastname: Wang
authors.forename: Sheng
authors.initials: S
authors.lastname: Zeng
authors.forename: Xu-Ming
authors.initials: XM
authors.lastname: Deng
mesh_terms: D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D032261:Picrorhiza / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D006027:Glycosides; D039823:Iridoids; D010936:Plant Extracts