Neural tonotopy in cochlear implants: an evaluation in unilateral cochlear implant patients with unilateral deafness and tinnitus.
In cochlear implants, the signal is filtered into different frequency bands and transmitted to electrodes along the cochlea. In this study the frequency-place function for electric hearing was investigated as a means to possibly improve speech coding by delivering information to the appropriate cochlear place. Fourteen subjects with functional hearing in the contralateral ear have been provided with a MED-EL cochlear implant in the deaf ear in order to reduce intractable tinnitus. Pitch scaling experiments were performed using single-electrode, constant-amplitude, constant-rate stimuli in the implanted ear, and acoustic sinusoids in the contralateral ear. The frequency-place function was calculated using the electrode position in the cochlea as obtained from postoperative skull radiographs. Individual frequency-place functions were compared to Greenwood's function in normal hearing. Electric stimulation elicited a low pitch in the apical region of the cochlea, and shifting the stimulating electrode towards the basal region elicited increasingly higher pitch. The frequency-place function did not show a significant shift relative to Greenwood's function. In cochlear implant patients with functional hearing in the non-implanted ear, electrical stimulation produced a frequency-place function that on average resembles Greenwood's function. These results differ from previously derived data.
Vermeire
Katrien
K
C. Doppler Laboratory for Active Implantable Systems, Institute of Ion Physics and Applied Physics, University of Innsbruck, Innsbruck, Austria. katrien.vermeire@uibk.ac.at
Nobbe
Andrea
A
Schleich
Peter
P
Nopp
Peter
P
Voormolen
Maurits H
MH
Van de Heyning
Paul H
PH
D000161:Acoustic Stimulation; D000328:Adult; D000368:Aged; D003051:Cochlea / Q000000981:diagnostic imaging; D003054:Cochlear Implants / Q000706:statistics & numerical data; D003638:Deafness / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D004558:Electric Stimulation; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008144:Loudness Perception; D008875:Middle Aged; D010898:Pitch Perception; D011859:Radiography; D012815:Signal Processing, Computer-Assisted; D014012:Tinnitus / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult