title: Treatment for late-onset obsessive-compulsive disorder with parkinsonism.
abstract: Dysfunction of the basal ganglia and frontal subcortical structures occurs in both obsessive-compulsive disorder and parkinsonism. Treatment of obsessive-compulsive disorder with parkinsonism is a therapeutic challenge, especially in old age as selective serotonin reuptake inhibitors may aggravate motor symptoms and worsen clinical conditions. The authors present a series of patients with late onset obsessive-compulsive disorder demonstrating improvement in obsessive-compulsive disorder as well as parkinsonian signs.
authors.affiliation: Department Of Psychiatry at Maulana Azad Medical College, New Delhi-110002, India. dralagrawal@hotmail.com
authors.forename: Arunlata
authors.initials: A
authors.lastname: Agarwal
authors.forename: Devdutta
authors.initials: D
authors.lastname: Biswas
authors.forename: Raja
authors.initials: R
authors.lastname: Sadhu
mesh_terms: D000328:Adult; D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000628:therapy*; D020734:Parkinsonian Disorders / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000929:Antidepressive Agents, Tricyclic; D000978:Antiparkinson Agents; D002997:Clomipramine