Multiple ocular abnormalities associated with trisomy 4p.
Ocular features associated with trisomy 4p have rarely been described. The authors have experienced multiple ocular abnormalities (bilateral cataracts, posterior synechiae, and posterior segment changes) associated with this chromosomal abnormality. It was presumed that these intraocular findings might be associated with the previous inflammatory process. In the current case, the patient recovered some useful vision after surgical removal of cataracts and intraocular lens implantations in both eyes. A detailed ophthalmic examination for patients with the autosomal imbalance is recom-mended.
Hong
Samin
S
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Kang
Sung Yong
SY
Seong
Gong Je
GJ
Shin
Joo Youn
JY
Kim
Chan Yun
CY
D000015:Abnormalities, Multiple / Q000235:genetics*; D000328:Adult; D001763:Blepharoptosis / Q000235:genetics; D002386:Cataract / Q000235:genetics; D002894:Chromosomes, Human, Pair 4; D004948:Esotropia / Q000235:genetics; D005124:Eye Abnormalities / Q000235:genetics*; D005143:Eyelids / Q000002:abnormalities; D005147:Facial Bones / Q000002:abnormalities; D005260:Female; D006801:Humans; D007621:Karyotyping; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification; D011859:Radiography; D012600:Scoliosis / Q000000981:diagnostic imaging / Q000235:genetics; D014314:Trisomy / Q000235:genetics*