title: Does breast feeding provide protection against acute appendicitis? A case-control study.
abstract: Breast feeding stimulates a more tolerant lymphoid tissue at the base of the appendix and this could provide protection against acute appendicitis. Two studies reported that children and adolescents with appendicitis were less likely to have been breast fed. In a case-control study of 200 children with histologically confirmed acute appendicitis matched by 200 siblings with the same sex and difference age - up to three-year-old - we found breast feeding in at least the first two months of life and for more than four months provides protection against acute appendicitis. These findings suggesting that breast feeding may possibly give protection against the development of appendicitis.
authors.affiliation: Instituto Materno Infantil Prof. Fernando Figueira (IMIP), Rua dos Coelhos, 300, Boa Vista, Recife, Pernambuco, Brazil. joaoguilherme@imip.org.br
authors.forename: João Guilherme Bezerra
authors.initials: JG
authors.lastname: Alves
authors.forename: José Natal
authors.initials: JN
authors.lastname: Figueiroa
authors.forename: Isabela
authors.initials: I
authors.lastname: Barros
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001064:Appendicitis / Q000517:prevention & control*; D001942:Breast Feeding; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male