title: Associations between the 11-bp deletion in the myostatin gene and carcass quality in Angus-sired cattle.
abstract: An 11-bp deletion in the bovine myostatin (MSTN) gene was identified as the causative mutation for the double-muscling phenotype in Belgian Blue and Asturiana cattle. More recently, this mutation was also identified in the South Devon breed of cattle, in which it has been found to be associated with a general increase in muscle mass. The present study found that the mutant allele was also segregating in a commercial population of Scottish Aberdeen Angus beef cattle. The mutation was found at a low frequency (0.04) with no animals homozygous for the mutation in the sample population (536 animals). The effects of this mutation on various carcass traits of economic interest were then tested. We found that the mutation significantly increased carcass weight, sirloin weight, hindquarter weight, muscle conformation score and eye muscle area, but had no effect on the fat traits.
authors.affiliation: The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Roslin BioCentre, Midlothian EH25 9PS, UK. jennifer.gill@roslin.ed.ac.uk
authors.forename: J L
authors.initials: JL
authors.lastname: Gill
authors.forename: S C
authors.initials: SC
authors.lastname: Bishop
authors.forename: C
authors.initials: C
authors.lastname: McCorquodale
authors.forename: J L
authors.initials: JL
authors.lastname: Williams
authors.forename: P
authors.initials: P
authors.lastname: Wiener
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics; D002417:Cattle / Q000235:genetics*; D017353:Gene Deletion; D008460:Meat; D055435:Myostatin / Q000235:genetics*
chemical_list: D055435:Myostatin