title: Glycoarrays--tools for determining protein-carbohydrate interactions and glycoenzyme specificity.
abstract: Carbohydrate arrays (glycoarrays) have recently emerged as a high-throughput tool for studying carbohydrate-binding proteins and carbohydrate-processing enzymes. A number of sophisticated array platforms that allow for qualitative and quantitative analysis of carbohydrate binding and modification on the array surface have been developed, including analysis by fluorescence spectroscopy, mass spectrometry and surface plasmon resonance spectroscopy. These platforms, together with examples of biologically-relevant applications are reviewed in this Feature Article.
authors.affiliation: Manchester Interdisciplinary Biocentre and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, UK M1 7DN.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Laurent
authors.forename: Josef
authors.initials: J
authors.lastname: Voglmeir
authors.forename: Sabine L
authors.initials: SL
authors.lastname: Flitsch
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D011506:Proteins / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D002241:Carbohydrates; D004798:Enzymes; D011506:Proteins