title: EST-based gene indices for the cattle fever tick, the horn fly, and the screwworm fly.
abstract: The southern cattle tick, Rhip,cephalus (Boophilus) microplus, the horn fly, Haematobia irritans, and the New World screwworm, Cochl,omyia hominivorax, are economically important parasites of cattle throughout the world. Understanding the biology and genomics of these pests is critical to developing novel control methods. We developed EST sequence databases for these parasites and used bioinformatic analysis to identify conceptual open reading frames and assigned Gene Ontology (GO) terms to those database transcripts that had informative BlasIX hits. Bloinformatic analysis showed that a large fraction of the tick database entries have no clear matches in other sequenced genomes. Several putative tick G protein-coupled receptors (GPCRs) were identified that mightserve as starting points to develop novel control technologies.
authors.forename: F D
authors.initials: FD
authors.lastname: Guerrero
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: V M
authors.initials: VM
authors.lastname: Nene
authors.forename: S E
authors.initials: SE
authors.lastname: Dowd
authors.forename: L
authors.initials: L
authors.lastname: Saldivar
mesh_terms: D000818:Animals; D018076:DNA, Complementary; D030541:Databases, Genetic; D020224:Expressed Sequence Tags; D016366:Open Reading Frames; D012333:RNA, Messenger / Q000235:genetics; D013987:Ticks / Q000235:genetics / Q000821:virology*
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger