title: Physiotherapy does not prevent, or hasten recovery from, ventilator-associated pneumonia in patients with acquired brain injury.
abstract: OBJECTIVE
  To investigate the effect of respiratory physiotherapy on the prevention and treatment of ventilator-associated pneumonia (VAP) for adults in an intensive care unit (ICU) with an acquired brain injury (ABI).
  
  
  METHODS
  Two-part, prospective, randomised controlled trial.
  
  
  METHODS
  A total of 144 subjects with ABI admitted with a Glasgow Coma Scale </=9, requiring intracranial pressure monitoring, and invasive mechanical ventilation (MV) for >24 h; 33 subjects were subsequently diagnosed with VAP.
  
  
  METHODS
  Respiratory physiotherapy comprised six treatments (positioning, manual hyperinflation and suctioning) in each 24-h period whilst on MV. The Control Group received standard medical/nursing care but no respiratory physiotherapy.
  
  
  RESULTS
  There were no significant differences between groups for incidence of VAP, duration of MV, length of ICU stay or clinical variables such as requirement for re-ventilation.
  
  
  CONCLUSIONS
  In adults with ABI, regular respiratory physiotherapy in addition to routine medical/nursing care does not appear to prevent VAP, reduce length of MV or ICU stay. Due to small numbers, it is not possible to draw any conclusions as to whether or not respiratory physiotherapy hastens recovery from VAP.
authors.affiliation: School of Physiotherapy, Curtin University of Technology, GPO Box U1987, Perth, WA, 6845, Australia. spatman1@nd.edu.au
authors.forename: Shane
authors.initials: S
authors.lastname: Patman
authors.forename: Sue
authors.initials: S
authors.lastname: Jenkins
authors.forename: Kathy
authors.initials: K
authors.lastname: Stiller
mesh_terms: D001930:Brain Injuries / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D007427:Intracranial Pressure; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D026741:Physical Therapy Modalities; D011014:Pneumonia / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control*; D020127:Recovery of Function; D012121:Respiration, Artificial / Q000009:adverse effects*