title: Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.
abstract: All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide<0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were no gender differences in type 1 in any age group, small ones in pediatric subgroups. In type 2 men predominated in ages above 40 years. Incidences of type 1 diabetes in both children and adults were very high and as high above age 50 years as in children. Incidence of type 2 was the highest reported from Sweden, to which new diagnostic criteria, a high degree of case-finding, and many elders, may have contributed, but results may also reflect a true increase in incidence of both types of diabetes.
authors.affiliation: Department of Internal Medicine, Central Hospital, S- 351 85 Vaxjo, Sweden. maria.thunander@ltkronoberg.se
authors.forename: M
authors.initials: M
authors.lastname: Thunander
authors.forename: C
authors.initials: C
authors.lastname: Petersson
authors.forename: K
authors.initials: K
authors.lastname: Jonzon
authors.forename: J
authors.initials: J
authors.lastname: Fornander
authors.forename: B
authors.initials: B
authors.lastname: Ossiansson
authors.forename: C
authors.initials: C
authors.lastname: Torn
authors.forename: S
authors.initials: S
authors.lastname: Edvardsson
authors.forename: M
authors.initials: M
authors.lastname: Landin-Olsson
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000097:blood; D002096:C-Peptide / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology*; D016883:Diabetic Ketoacidosis / Q000097:blood; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D013548:Sweden / Q000453:epidemiology
chemical_list: D001323:Autoantibodies; D002096:C-Peptide; C024211:islet cell antibody