Treatment for late-onset obsessive-compulsive disorder with parkinsonism.
Dysfunction of the basal ganglia and frontal subcortical structures occurs in both obsessive-compulsive disorder and parkinsonism. Treatment of obsessive-compulsive disorder with parkinsonism is a therapeutic challenge, especially in old age as selective serotonin reuptake inhibitors may aggravate motor symptoms and worsen clinical conditions. The authors present a series of patients with late onset obsessive-compulsive disorder demonstrating improvement in obsessive-compulsive disorder as well as parkinsonian signs.
Agarwal
Arunlata
A
Department Of Psychiatry at Maulana Azad Medical College, New Delhi-110002, India. dralagrawal@hotmail.com
Biswas
Devdutta
D
Sadhu
Raja
R
D000328:Adult; D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000628:therapy*; D020734:Parkinsonian Disorders / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome
D000929:Antidepressive Agents, Tricyclic; D000978:Antiparkinson Agents; D002997:Clomipramine