title: Improving Diabetes Care in Practice: findings from the TRANSLATE trial.
abstract: OBJECTIVE
  The purpose of this study was to determine whether implementation of a multicomponent organizational intervention can produce significant change in diabetes care and outcomes in community primary care practices.
  
  
  METHODS
  This was a group-randomized, controlled clinical trial evaluating the practical effectiveness of a multicomponent intervention (TRANSLATE) in 24 practices. The intervention included implementation of an electronic diabetes registry, visit reminders, and patient-specific physician alerts. A site coordinator facilitated previsit planning and a monthly review of performance with a local physician champion. The principle outcomes were the percentage of patients achieving target values for the composite of systolic blood pressure (SBP) <130 mmHg, LDL cholesterol <100 mg/dl, and A1C <7.0% at baseline and 12 months. Six process measures were also followed.
  
  
  RESULTS
  Over 24 months, 69,965 visits from 8,405 adult patients with type 2 diabetes were recorded from 238 health care providers in 24 practices from 17 health systems. Diabetes process measures increased significantly more in intervention than in control practices, giving net increases as follows: foot examinations 35.0% (P < 0.0.001); annual eye examinations 25.9% (P < 0.001); renal testing 28.5% (P < 0.001); A1C testing 8.1%(P < 0.001); blood pressure monitoring 3.5% (P = 0.05); and LDL testing 8.6% (P < 0.001). Mean A1C adjusted for age, sex, and comorbidity decreased significantly in intervention practices (P < 0.02). At 12 months, intervention practices had significantly greater improvement in achieving recommended clinical values for SBP, A1C, and LDL than control clinics (P = 0.002).
  
  
  CONCLUSIONS
  Introduction of a multicomponent organizational intervention in the primary care setting significantly increases the percentage of type 2 diabetic patients achieving recommended clinical outcomes.
authors.affiliation: University of Minnesota, Minneapolis, Minnesota, USA. peter223@umn.edu
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Peterson
authors.forename: David M
authors.initials: DM
authors.lastname: Radosevich
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: O'Connor
authors.forename: John A
authors.initials: JA
authors.lastname: Nyman
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Prineas
authors.forename: Steven A
authors.initials: SA
authors.lastname: Smith
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Arneson
authors.forename: Victor A
authors.initials: VA
authors.lastname: Corbett
authors.forename: Joyce C
authors.initials: JC
authors.lastname: Weinhandl
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Lange
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hannan
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010818:Practice Patterns, Physicians'; D011320:Primary Health Care / Q000458:organization & administration* / Q000592:standards; D011785:Quality Assurance, Health Care