title: Salivary changes and dental erosion in bulimia nervosa.
abstract: OBJECTIVE
  Our aim was to study if bulimia nervosa (BN) has an impact on salivary gland function and if such changes are related to dental erosion.
  
  
  METHODS
  Twenty women with BN and twenty age- and gender-matched controls participated. Flow rate and composition of whole and glandular saliva, as well as feeling of oral dryness were measured. Dental erosion was measured on casts.
  
  
  RESULTS
  Compared with control subjects, unstimulated whole saliva (UWS) flow rate was reduced in persons with BN, primarily owing to intake of medication (P = .007). No major compositional salivary changes were found. In the BN group, the dental erosion score was highest and complaints of oral dryness were more frequent.
  
  
  CONCLUSIONS
  The BN persons had impaired UWS, mainly owing to medication; increased feeling of oral dryness; and more dental erosion. Dental erosion was related to the duration of eating disorder, whereas no effect of vomiting frequency or intake of acidic drinks on reduced UWS was observed.
authors.affiliation: Department of Odontology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. awd@odont.ku.dk
authors.forename: Anja Weirsøe
authors.initials: AW
authors.lastname: Dynesen
authors.forename: Allan
authors.initials: A
authors.lastname: Bardow
authors.forename: Birgit
authors.initials: B
authors.lastname: Petersson
authors.forename: Lene Rindal
authors.initials: LR
authors.lastname: Nielsen
authors.forename: Birgitte
authors.initials: B
authors.lastname: Nauntofte
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects; D001628:Beverages / Q000009:adverse effects; D052018:Bulimia Nervosa / Q000097:blood / Q000150:complications*; D002245:Carbon Dioxide / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012044:Regression Analysis; D012463:Saliva / Q000737:chemistry / Q000378:metabolism; D012636:Secretory Rate; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects; D014077:Tooth Erosion / Q000209:etiology*; D014987:Xerostomia / Q000209:etiology; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents; D002245:Carbon Dioxide; D017367:Selective Serotonin Reuptake Inhibitors