title: Engineering cytochrome P450 enzymes for improved activity towards biomimetic 1,4-NADH cofactors.
authors.affiliation: Department of Chemical Engineering, University of California, Berkeley, CA 94720, USA.
authors.forename: Jessica D
authors.initials: JD
authors.lastname: Ryan
authors.forename: Richard H
authors.initials: RH
authors.lastname: Fish
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Clark
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism*; D055162:Biocatalysis; D040761:Biomimetic Materials / Q000378:metabolism*; D019475:Camphor 5-Monooxygenase / Q000235:genetics* / Q000378:metabolism*; D003067:Coenzymes / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism*; D009243:NAD / Q000378:metabolism*; D009251:NADPH-Ferrihemoprotein Reductase / Q000235:genetics* / Q000378:metabolism*; D009536:Niacinamide / Q000031:analogs & derivatives / Q000378:metabolism; D010084:Oxidation-Reduction; D015202:Protein Engineering; D016958:Pseudomonas putida / Q000201:enzymology
chemical_list: D001426:Bacterial Proteins; D003067:Coenzymes; D009243:NAD; C004283:N-methyl-1,4-dihydronicotinamide; D009536:Niacinamide; D003577:Cytochrome P-450 Enzyme System; D019475:Camphor 5-Monooxygenase; D009251:NADPH-Ferrihemoprotein Reductase; C052423:flavocytochrome P450 BM3 monoxygenases