title: The effect of peritoneal dialysate on DXA bone densitometry results in patients with end-stage renal disease.
abstract: The bone mineral density of patients undergoing peritoneal dialysis (PD) is low compared to a healthy population. No studies have been conducted to investigate whether the presence of peritoneal dialysate affects dual-energy X-ray absorptiometry (DXA) results. We hypothesized that the presence of peritoneal dialysate would not affect the measurement of bone mineral density (BMD) or bone mineral content (BMC) in the spine. Thirty patients on PD had DXA scans of the lumbar spine and hip completed before and after the drainage of peritoneal dialysate. A paired t-test was used to compare the difference in area, BMC, and BMD before and after drainage of dialysate. A significant difference was found in the BMC of the spine before and after the drainage of dialyzate. We recommend that peritoneal dialyzate be removed prior to scanning patients on PD and that densitometry technologists should be observant about the presence of peritoneal dialysate.
authors.affiliation: University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
authors.forename: Merry Lynn
authors.initials: ML
authors.lastname: Mann
authors.forename: Denyse
authors.initials: D
authors.lastname: Thornley-Brown
authors.forename: Ruth
authors.initials: R
authors.lastname: Campbell
authors.forename: Emmy
authors.initials: E
authors.lastname: Bell
authors.forename: Leandria
authors.initials: L
authors.lastname: Burroughs
authors.forename: Nancy
authors.initials: N
authors.lastname: Nunnally
authors.forename: Rui
authors.initials: R
authors.lastname: Feng
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Morgan
mesh_terms: D015502:Absorptiometry, Photon; D015519:Bone Density / Q000187:drug effects*; D015314:Dialysis Solutions / Q000009:adverse effects; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D016014:Linear Models; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects
chemical_list: D015314:Dialysis Solutions