Subtractive assembly of DNA nanoarchitectures driven by fuel strand displacement.
Herein we demonstrate that flexible DNA architectures with larger cavities can be efficiently constructed by first assembling a relatively more rigid DNA tile architecture and subsequently subtracting a center tile through fuel strand displacement; such structures are otherwise difficult to obtain if the center tile is missing in the beginning, proving a new strategy for DNA self-assembly.
Li
Zhe
Z
Department of Chemistry & Biochemistry, Arizona State University, Tempe, AZ 85287, USA.
Ke
Yonggang
Y
Lin
Chenxiang
C
Yan
Hao
H
Liu
Yan
Y
D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D009690:Nucleic Acid Conformation; D010316:Particle Size
D004247:DNA