[Biological effects of electromagnetic radiation of extremely high frequencies combined with physiologically active compounds].
The study of the action of the electromagnetic radiation (EMR) of low intensity (10 microW/cm2) in the range of frequencies 120-170 GHz at the test-reaction of Infusoria Paramecium caudatum was carried out. The resonant character of the effects was established. The EMR action at 156.6 and 161.3 GHz caused the increase of infusorians mobility, the action at frequencies 151.8, 155.7, 167.1 GHz caused the mobility reduction. Isolated and combined with EMR effects of nicotine (10(-4)-10(-15) mol/l) and antimicrobial drug metronidazole (10(-5), 10(-8), 10(-9) mol/l) were investigated. The radiation at the frequency 167.1 GHz was shown to reduce the effect of nicotine (10(-9) mol/l) and to enhance the effect of metronidazole (10(-9) mol/l). This phenomenon may be explained by different effects of the substances in low concentration at the water hydrogen bonds net structure.
Rogacheva
S M
SM
Denisova
S A
SA
Shul'gin
S V
SV
Somov
A Iu
AIu
Kuznetsov
P E
PE
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology*; D002465:Cell Movement / Q000187:drug effects / Q000528:radiation effects; D004305:Dose-Response Relationship, Drug; D004307:Dose-Response Relationship, Radiation; D006860:Hydrogen Bonding / Q000187:drug effects / Q000528:radiation effects; D008795:Metronidazole / Q000494:pharmacology*; D008872:Microwaves; D009538:Nicotine / Q000494:pharmacology*; D048488:Paramecium caudatum / Q000187:drug effects* / Q000528:radiation effects*; D013997:Time Factors
D000981:Antiprotozoal Agents; D008795:Metronidazole; D009538:Nicotine