Neonatal stroke.
OBJECTIVE
The purpose of this manuscript is to review various clinical and neuroimaging features of vascular pathology in the fetus and neonate.


METHODS
A PubMed search of literature from 1978 to 2007 was performed using key search terms. Scientific papers pertinent to fetal and neonatal strokes were included and analysed.


RESULTS
The analysis of the multiple causes of fetal and neonatal vascular compromise including maternal, placental, infectious, metabolic/prothrombotic, traumatic and cardiac factors, current therapy and outcome data, is presented and discussed throughout the length of the paper.


CONCLUSIONS
With increasing vigilance among physicians and improved neuroimaging modalities, the diagnosis of neonatal stroke is now made earlier, with increasing frequency and greater accuracy.
Riel-Romero
Rosario Maria S
RM
Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA. rrielr@lsuhsc.edu
D000818:Animals; D000831:Animals, Newborn; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D004195:Disease Models, Animal; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D008279:Magnetic Resonance Imaging / Q000379:methods; D020521:Stroke / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods