title: Chinese dumpling scare hits Japan--a case of methamidophos food poisoning.
abstract: An outbreak of food poisoning that affected at least ten people in various regions of Japan was traced to exposure to Chinese dumplings contaminated with the organophosphate insecticide Methamidophos. We experienced the most serious case, a five years old girl, who suffered coma. She presented with features of cholinergic overactivity and her serum cholinesterase activity was 9 U/l. We started intravenous treatment with pralidoxime iodide, atropine sulfate, and midazolam. Her symptoms improved gradually and she was discharged on day 25 without any sequelae. Though poisoning attributed to organophosphate insecticides has become less common in recent years, it is even more important to diagnose the problem rapidly based on the characteristic symptoms and to start specific treatment at the earliest possible stage after poisoning.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Sumi
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Oode
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D001285:Atropine / Q000627:therapeutic use; D002675:Child, Preschool; D002681:China; D003128:Coma / Q000139:chemically induced / Q000209:etiology; D005260:Female; D005517:Foodborne Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D007564:Japan / Q000453:epidemiology; D008874:Midazolam / Q000627:therapeutic use; D009946:Organothiophosphorus Compounds / Q000506:poisoning*; D011220:Pralidoxime Compounds / Q000627:therapeutic use
chemical_list: D007306:Insecticides; D009946:Organothiophosphorus Compounds; D011220:Pralidoxime Compounds; D001285:Atropine; C014655:methamidophos; C028797:pralidoxime; D008874:Midazolam