title: Seasonal effects on the nasolabial skin condition.
abstract: In the present work, nasolabial skin condition and the influence of seasonal changes during autumn and winter were studied in 16 healthy female volunteers. Apart from visual scoring of erythema and skin scaliness, transepidermal water loss (TEWL), skin hydration, apparent skin pH, skin colour and skin desquamation were biophysically measured. The study results showed that nasolabial TEWL was significantly higher during wintertime than in autumn. Also skin colour measurements and squamometry scorings revealed higher values, indicating a more reddish and scaly nasolabial skin during winter compared to autumn. Results from tape stripping and skin surface lipid analysis by high-performance thin-layer chromatography demonstrated significant differences for triglycerides and cholesterol esters, indicating a functionally inferior hydrolipidic layer during the winter season.
authors.affiliation: Department of Toxicology, Dermato-Cosmetology and Pharmacognosy, Vrije Universiteit Brussel (VUB), Brussels, Belgium. kdepaepe@vub.ac.be
authors.forename: K
authors.initials: K
authors.lastname: De Paepe
authors.forename: E
authors.initials: E
authors.lastname: Houben
authors.forename: R
authors.initials: R
authors.lastname: Adam
authors.forename: J-P
authors.initials: JP
authors.lastname: Hachem
authors.forename: D
authors.initials: D
authors.lastname: Roseeuw
authors.forename: V
authors.initials: V
authors.lastname: Rogiers
mesh_terms: D000328:Adult; D002788:Cholesterol Esters / Q000378:metabolism; D002855:Chromatography, Thin Layer; D004890:Erythema / Q000473:pathology; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009666:Nose; D012621:Seasons; D012720:Severity of Illness Index; D012867:Skin / Q000378:metabolism / Q000473:pathology*; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology*; D012880:Skin Pigmentation; D014280:Triglycerides / Q000378:metabolism; D014870:Water Loss, Insensible; D055815:Young Adult
chemical_list: D002788:Cholesterol Esters; D014280:Triglycerides