Hyper interleukin-10 in an HIV-positive child with t-cell lymphoma and candidal sepsis.
We describe a case in which a human immunodeficiency virus (HIV)-positive child presented in severe metabolic acidosis secondary to his candidal sepsis and T-cell lymphoma, a rare finding in pediatric AIDS. Significantly elevated levels of Interleukin-10 (IL-10) were found in the patient's serum, which may have played a role in acute demise.
Lighter
Jennifer
J
Saul Krugman Division of Pediatric Infectious Diseases and Immunology, New York University School of Medicine, New York, New York. lightj03@med.nyu.edu
Tse
Doris B
DB
Kaul
Aditya
A
Borkowsky
William
W
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D000293:Adolescent; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications* / Q000382:microbiology; D017809:Fatal Outcome; D016469:Fungemia / Q000150:complications* / Q000382:microbiology; D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D016753:Interleukin-10 / Q000378:metabolism*; D016483:Lymphoma, AIDS-Related / Q000150:complications; D016399:Lymphoma, T-Cell / Q000150:complications*; D008297:Male; D015854:Up-Regulation
D016753:Interleukin-10