title: Response of human dental pulp capped with MTA and calcium hydroxide powder.
abstract: OBJECTIVE
  To compare the response of human dental pulp capped with a mineral trioxide aggregate (MTA) and Ca(OH)2 powder.
  
  
  METHODS
  Pulp exposures were performed on the occlusal floor of 40 permanent premolars. The pulp was then capped with either Ca(OH)2 powder (CH) or MTA and restored with resin composite. After 30 days (groups CH30 and MTA30) and 60 days (groups CH60 and MTA60), the teeth were extracted and processed for HE and categorized in a histological score system. The data were subjected to Kruskal-Wallis and Conover tests (alpha = 0.05).
  
  
  RESULTS
  In regard to dentin bridge formation, CH30 showed a tendency towards superior performance compared to MTA30 (p > 0.05), although the products showed comparable results at day 60. In the item "Inflammation" and "General State of the Pulp" (p > 0.05), CH showed a tendency towards presenting a higher inflammatory response. In the item "Other Pulpal Findings," MTA and Ca(OH)2 showed equal and excellent performance after 30 and 60 days (p > 0.05).
  
  
  CONCLUSIONS
  After 30 days, Ca(OH)2 powder covered with calcium hydroxide cement showed faster hard tissue bridge formation compared to MTA. After 60 days, Ca(OH)2 powder or MTA materials showed a similar and excellent histological response with the formation of a hard tissue bridge in almost all cases with low inflammatory infiltrate.
authors.affiliation: Department of Dental Materials, School of Dentistry, University Brás Cubas, São Paulo, SP, Brazil.
authors.forename: M L R
authors.initials: ML
authors.lastname: Accorinte
authors.forename: Alessandro D
authors.initials: AD
authors.lastname: Loguercio
authors.forename: Alessandra
authors.initials: A
authors.lastname: Reis
authors.forename: E
authors.initials: E
authors.lastname: Carneiro
authors.forename: R H M
authors.initials: RH
authors.lastname: Grande
authors.forename: S S
authors.initials: SS
authors.lastname: Murata
authors.forename: R
authors.initials: R
authors.lastname: Holland
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000627:therapeutic use*; D001641:Bicuspid; D017610:Calcium Compounds / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000627:therapeutic use*; D003188:Composite Resins; D003764:Dental Materials / Q000627:therapeutic use*; D003782:Dental Pulp / Q000187:drug effects* / Q000473:pathology; D003785:Dental Pulp Capping / Q000379:methods*; D003789:Dental Pulp Exposure / Q000628:therapy; D003793:Dental Restoration, Permanent; D003809:Dentin, Secondary / Q000187:drug effects / Q000473:pathology; D004338:Drug Combinations; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008422:Materials Testing; D010087:Oxides / Q000627:therapeutic use*; D020011:Protective Agents / Q000627:therapeutic use*; D011671:Pulpitis / Q000473:pathology; D017640:Silicates / Q000627:therapeutic use*; D013997:Time Factors; D014098:Toothache / Q000209:etiology
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003188:Composite Resins; D003764:Dental Materials; D004338:Drug Combinations; D010087:Oxides; D020011:Protective Agents; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide