title: Blood loss during transvaginal oocyte retrieval.
abstract: OBJECTIVE
  Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss.
  
  
  METHODS
  One hundred and fifty consecutive women undergoing oocyte retrieval were recruited. They underwent blood test assessment and ultrasonographic transvaginal evaluation at three different times: (1) immediately before initiating oocyte retrieval, (2) 4-6 h later, and (3) 72 h later.
  
  
  RESULTS
  At 4-6 h after oocyte retrieval, the red blood cell count and the hemoglobin concentration were significantly reduced, whereas pelvic free fluid had significantly increased. The estimated median (Interquartile range) blood loss was 72 (-8/162) ml. None of the recruited women was found to have a hemoglobin reduction >2 g/day or an increase in the pelvic free fluid >200 ml or a calculated blood loss >500 ml (0.0%, 95% CI: 0.0-2.4%). No significant worsening from baseline was observed at the 72 h evaluation.
  
  
  CONCLUSIONS
  The quantity of blood loss following oocyte retrieval is clinically unremarkable in the vast majority of women.
authors.affiliation: Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Ragni
authors.forename: Claudia
authors.initials: C
authors.lastname: Scarduelli
authors.forename: Graziella
authors.initials: G
authors.lastname: Calanna
authors.forename: Giulia
authors.initials: G
authors.lastname: Santi
authors.forename: Laura
authors.initials: L
authors.lastname: Benaglia
authors.forename: Edgardo
authors.initials: E
authors.lastname: Somigliana
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006801:Humans; D054315:Oocyte Retrieval / Q000379:methods*; D018709:Statistics, Nonparametric