title: Prostate-specific antigen in the cerebrospinal fluid: a marker of local disease.
abstract: Leptomeningeal involvement from prostate cancer is a rare complication with dismal prognosis. Prostate-specific antigen in the cerebrospinal fluid may be found elevated and can be used as a marker for local disease. We present the case of a patient with prostate cancer and leptomeningeal metastases who had high levels of prostate-specific antigen in the cerebrospinal fluid.
authors.affiliation: Department of Oncology, Nicosia General Hospital, P. O. Box 1450, Nicosia, Cyprus. georgeorphanosvp@hotmail.com
authors.forename: George
authors.initials: G
authors.lastname: Orphanos
authors.forename: George
authors.initials: G
authors.lastname: Ioannidis
authors.forename: Michael
authors.initials: M
authors.lastname: Michael
authors.forename: George
authors.initials: G
authors.lastname: Kitrou
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000166:cytology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D008727:Methotrexate / Q000627:therapeutic use; D017430:Prostate-Specific Antigen / Q000134:cerebrospinal fluid*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000964:Antimetabolites, Antineoplastic; D017430:Prostate-Specific Antigen; D008727:Methotrexate