title: Synchronous primary tumors of the female genital tract: a single center experience.
abstract: BACKGROUND
  The present study aims to characterize the women diagnosed with synchronous primary gynecological tumors with an emphasis on risk factors.
  
  
  METHODS
  A total of 21 patients were identified with synchronous primary gynecological tumors between 2000 and 2006. Demographic, clinical and pathologic data were obtained from medical records and pathology reports.
  
  
  RESULTS
  The majority of the study population (52.4%) was diagnosed with independent primary endometrial and ovarian tumors. The most common presenting symptoms were pelvic pain and abnormal vaginal bleeding. Tobacco use was significantly more frequent in women with synchronous cervical-ovarian tumors. There was no statistically significant difference in exogenous hormone use among patients with different synchronous tumors. Diabetes mellitus and hypertension were significantly more frequent in women with endometrial-ovarian tumors. Although the women with synchronous cervical-ovarian tumors were significantly younger and leaner, they had shorter survival periods.
  
  
  CONCLUSIONS
  Synchronous primary gynecologic tumors are usually detected in relatively older, overweight, multiparous and postmenopausal women with personal history of diabetes mellitus or hypertension. Synchronous primary tumors of endometrium and ovary are supposed to have better prognosis as they are diagnosed at early stage and low grade.
authors.affiliation: Department of Gynecologic Oncology, Dr Zekai Tahir Burak Women Health Research and Education Hospital, Ankara, Turkey.
authors.forename: Tayfun
authors.initials: T
authors.lastname: Gungor
authors.forename: Mine
authors.initials: M
authors.lastname: Kanat-Pektas
authors.forename: Emin
authors.initials: E
authors.lastname: Ustunyurt
authors.forename: Leyla
authors.initials: L
authors.lastname: Mollamahmutoglu
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology*; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D018269:Carcinoma, Endometrioid; D015331:Cohort Studies; D016889:Endometrial Neoplasms / Q000453:epidemiology*; D005260:Female; D006106:Granulosa Cell Tumor / Q000453:epidemiology*; D006784:Hospitals, Teaching; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D050177:Overweight; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D014421:Turkey / Q000453:epidemiology