title: What makes a fly enter diapause?
abstract: Diapause is a dormant state that insects may undergo as a response to changing environmental conditions. In flies, like many insects inhabiting temperate zones, diapause occurs generally during the winter months when ambient temperatures are cool and food sources scarce. Whilst the environmental factors involved in determining diapause have been known for a long time, the genes and molecular events controling its initiation are poorly understood. Here I outline the factors that initiate diapause and highlight recent studies that implicate insulin signaling in its control.
authors.affiliation: Cell Biology and Development Group, Department of Biosciences, University of Kent, Canterbury, Kent, CT2 7NJ, United Kingdom. M.J.Allen@kent.ac.uk
authors.forename: Marcus J
authors.initials: MJ
authors.lastname: Allen
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D004175:Diptera / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D004331:Drosophila melanogaster / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D005260:Female; D017344:Genes, Insect; D007328:Insulin / Q000502:physiology; D008297:Male; D008954:Models, Biological; D017440:Photoperiod; D012098:Reproduction / Q000502:physiology; D012621:Seasons; D015398:Signal Transduction; D013696:Temperature
chemical_list: D007328:Insulin