Assessment of risk factors for survival of neonates born after second-trimester PPROM.
OBJECTIVE
Assess fetal risk factors which impact survival of infants delivered after second-trimester PPROM.


METHODS
Clinical records of 87 patients, who all had second-trimester rupture of membranes between 14+0 and 24+6 weeks of gestation treated January 1998 to July 2005 were reviewed regarding perinatal outcome. This study is based on 25 surviving infants.


RESULTS
13 of these 25 infants died in the hospital. Survivors had a higher birth weight (p=0.008) and higher Apgar scores after 5 min (p=0.005) than those infants dying. No differences in UA pH, the need of catecholamines and no association between histological verified chorioamnionitis and early onset sepsis were seen between survivors and nonsurvivors.


CONCLUSIONS
Higher gestational age at birth, higher birth weight, the absence of histologically verified chorioamnionitis and 5 min Apgar scores of >or= than 6 have positive prognostic value for survival of neonates delivered preterm after second-trimester PPROM.
Pristauz
Gunda
G
Department of Gynecology and Obstetrics, Medical University of Graz, Graz, Austria. gunda.pristauz@klinikum-graz.at
Bader
Arnim A
AA
Schwantzer
Gerold
G
Kutschera
Jörg
J
Lang
Uwe
U
D000328:Adult; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012307:Risk Factors; D016019:Survival Analysis