Engineering cytochrome P450 enzymes for improved activity towards biomimetic 1,4-NADH cofactors.
Ryan
Jessica D
JD
Department of Chemical Engineering, University of California, Berkeley, CA 94720, USA.
Fish
Richard H
RH
Clark
Douglas S
DS
D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism*; D055162:Biocatalysis; D040761:Biomimetic Materials / Q000378:metabolism*; D019475:Camphor 5-Monooxygenase / Q000235:genetics* / Q000378:metabolism*; D003067:Coenzymes / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism*; D009243:NAD / Q000378:metabolism*; D009251:NADPH-Ferrihemoprotein Reductase / Q000235:genetics* / Q000378:metabolism*; D009536:Niacinamide / Q000031:analogs & derivatives / Q000378:metabolism; D010084:Oxidation-Reduction; D015202:Protein Engineering; D016958:Pseudomonas putida / Q000201:enzymology
D001426:Bacterial Proteins; D003067:Coenzymes; D009243:NAD; C004283:N-methyl-1,4-dihydronicotinamide; D009536:Niacinamide; D003577:Cytochrome P-450 Enzyme System; D019475:Camphor 5-Monooxygenase; D009251:NADPH-Ferrihemoprotein Reductase; C052423:flavocytochrome P450 BM3 monoxygenases