title: Assemblies of DivIVA mark sites for hyphal branching and can establish new zones of cell wall growth in Streptomyces coelicolor.
abstract: Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.
authors.affiliation: Department of Cell and Organism Biology, Lund University, Sölvegatan 35, 223 62 Lund, Sweden.
authors.forename: Antje Marie
authors.initials: AM
authors.lastname: Hempel
authors.forename: Sheng-bing
authors.initials: SB
authors.lastname: Wang
authors.forename: Michal
authors.initials: M
authors.lastname: Letek
authors.forename: José A
authors.initials: JA
authors.lastname: Gil
authors.forename: Klas
authors.initials: K
authors.lastname: Flärdh
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D002473:Cell Wall / Q000378:metabolism*; D025301:Hyphae / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D010457:Peptidoglycan / Q000378:metabolism; D048372:Streptomyces coelicolor / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D018797:Cell Cycle Proteins; C104636:DivIVA protein, bacteria; D010457:Peptidoglycan