Thrombotic thrombocytopenic purpura in a patient with very early pregnancy: clinical presentation and autopsy findings.
Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy leading to microvascular occlusion resulting in ischemic dysfunction of various organs. Pregnancy has been thought to precipitate it during second and third trimester, but its reports in first trimester are extremely rare. We report the clinical protocol of a young lady with 5-week period of gestation, who presented with fever, seizures and altered sensorium, and succumbed to her illness during an episode of seizure. Complete autopsy findings are also presented in detail.
Sharma
Aman
A
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India. amansharma74@yahoo.com
Radotra
Bishan
B
Wanchu
Ajay
A
Malhotra
Pankaj
P
Singh
Surjit
S
Varma
Subhash
S
D000328:Adult; D001344:Autopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000473:pathology*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000473:pathology*