Chinese dumpling scare hits Japan--a case of methamidophos food poisoning.
An outbreak of food poisoning that affected at least ten people in various regions of Japan was traced to exposure to Chinese dumplings contaminated with the organophosphate insecticide Methamidophos. We experienced the most serious case, a five years old girl, who suffered coma. She presented with features of cholinergic overactivity and her serum cholinesterase activity was 9 U/l. We started intravenous treatment with pralidoxime iodide, atropine sulfate, and midazolam. Her symptoms improved gradually and she was discharged on day 25 without any sequelae. Though poisoning attributed to organophosphate insecticides has become less common in recent years, it is even more important to diagnose the problem rapidly based on the characteristic symptoms and to start specific treatment at the earliest possible stage after poisoning.
Sumi
Yuka
Y
Oode
Yasumasa
Y
Tanaka
Hiroshi
H
D001285:Atropine / Q000627:therapeutic use; D002675:Child, Preschool; D002681:China; D003128:Coma / Q000139:chemically induced / Q000209:etiology; D005260:Female; D005517:Foodborne Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D007564:Japan / Q000453:epidemiology; D008874:Midazolam / Q000627:therapeutic use; D009946:Organothiophosphorus Compounds / Q000506:poisoning*; D011220:Pralidoxime Compounds / Q000627:therapeutic use
D007306:Insecticides; D009946:Organothiophosphorus Compounds; D011220:Pralidoxime Compounds; D001285:Atropine; C014655:methamidophos; C028797:pralidoxime; D008874:Midazolam