title: The effects of methanolic extracts of ginger (Zingiber officinale) on human sperm parameters; an in vitro study.
abstract: This study was conducted on Zingiber officinale or ginger on motility, grading and morphological aspects of human sperm. Thirty human semen samples were obtained from the local hospital. The samples were swim up by Ham's F10. The samples (0.9 mL) were treated by 0.1 mL of ginger methanolic extracts (0.1, 0.2, 0.4 and 0.6% concentration). Sperm motility, grading and morphology parameters were assessed using light microscope at 0, 2, 4, 8 and 24 h after treatment. Dose and time-dependent decreases in motility accompanied by concomitant decrease in grading 3 and 4 were noticed. Morphologic profiles of the sperms were changed under different doses of ginger on the basis of time of assess. These data indicate that some exhibits a lower percentage of motility and grading when methanolic ginger is added to semen fluid. According to the results it would be concluded that ginger can induce the toxic effects on sperm parameters.
authors.affiliation: Department of Fertility and Infertility, Fateme Zahra Hospital, Babol University of Medical Sciences, Babol, Iran.
authors.forename: S G A
authors.initials: SG
authors.lastname: Jorsaraei
authors.forename: Y R
authors.initials: YR
authors.lastname: Yousefnia
authors.forename: M
authors.initials: M
authors.lastname: Zainalzadeh
authors.forename: A A
authors.initials: AA
authors.lastname: Moghadamnia
authors.forename: A A
authors.initials: AA
authors.lastname: Beiky
authors.forename: M Rayati
authors.initials: MR
authors.lastname: Damavandi
mesh_terms: D048430:Cell Shape / Q000187:drug effects; D020939:Zingiber officinale / Q000737:chemistry*; D006801:Humans; D008297:Male; D000432:Methanol; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000166:cytology / Q000187:drug effects*
chemical_list: D010936:Plant Extracts; D000432:Methanol