title: Tramadol as a local anaesthetic in tendon repair surgery of the hand.
abstract: This double-blind pilot study compared the local anaesthetic effects of tramadol plus adrenaline with lidocaine plus adrenaline during surgery to repair hand tendons. Twenty patients were randomly allocated to receive either 5% tramadol plus adrenaline (n = 10) or 2% lidocaine plus adrenaline (n = 10). Injection site pain and local skin reactions were recorded. At 1-min intervals after injection of the anaesthetic agent, the degree of sensory blockade was assessed by the patient reporting the extent to which they felt a pinprick, light touch and a cold sensation. Pain felt during surgical incision was also recorded. There was no difference in the quality of sensory blockade or the incidence of side effects between the two groups. Only patients treated with tramadol did not require additional post-operative analgesia. A combination of tramadol plus adrenaline provided a local anaesthetic effect similar to that of lidocaine plus adrenaline.
authors.affiliation: Department of Plastic and Reconstructive Surgery, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak, Turkey. eksalk@superonline.com
authors.forename: E
authors.initials: E
authors.lastname: Kargi
authors.forename: O
authors.initials: O
authors.lastname: Babuccu
authors.forename: H
authors.initials: H
authors.lastname: Altunkaya
authors.forename: M
authors.initials: M
authors.lastname: Hosnuter
authors.forename: Y
authors.initials: Y
authors.lastname: Ozer
authors.forename: B
authors.initials: B
authors.lastname: Babuccu
authors.forename: C
authors.initials: C
authors.lastname: Payasli
mesh_terms: D000293:Adolescent; D000322:Adrenergic Agonists / Q000627:therapeutic use; D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D019162:Anesthetics, Combined / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000627:therapeutic use*; D004311:Double-Blind Method; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006225:Hand / Q000033:anatomy & histology / Q000601:surgery*; D006230:Hand Injuries / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D013710:Tendons / Q000473:pathology / Q000601:surgery*; D014147:Tramadol / Q000627:therapeutic use*
chemical_list: D000322:Adrenergic Agonists; D000701:Analgesics, Opioid; D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D014147:Tramadol; D008012:Lidocaine; D004837:Epinephrine