title: [Alendronate].
abstract: Alendronate is one of a few pharmaceutical agents that have evidence to protect both vertebral and non-vertebral fracture. Here I review its effects on fracture prevention, as well as on surrogate markers such as bone mineral density, height loss, metabolic bone markers. Its effects on activities of daily living and quality of life will also be touched upon.
authors.affiliation: Teikyo University Chiba Medical Center, Third Department of Medicine.
authors.forename: Ryo
authors.initials: R
authors.lastname: Okazaki
mesh_terms: D000203:Activities of Daily Living; D019386:Alendronate / Q000627:therapeutic use*; D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D005260:Female; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic
chemical_list: D050071:Bone Density Conservation Agents; D019386:Alendronate