UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation.
Szpurka
H
H
Gondek
L P
LP
Mohan
S R
SR
Hsi
E D
ED
Theil
K S
KS
Maciejewski
J P
JP
D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D019943:Amino Acid Substitution; D000753:Anemia, Refractory / Q000145:classification / Q000175:diagnosis / Q000235:genetics*; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics; D019656:Loss of Heterozygosity / Q000235:genetics*; D008875:Middle Aged; D020125:Mutation, Missense; D010641:Phenotype; D010766:Phosphorylation; D017354:Point Mutation; D020641:Polymorphism, Single Nucleotide; D011499:Protein Processing, Post-Translational; D053628:Receptors, Thrombopoietin / Q000235:genetics*; D050799:STAT5 Transcription Factor / Q000378:metabolism; D013922:Thrombocytosis / Q000175:diagnosis / Q000235:genetics*; D024182:Uniparental Disomy / Q000235:genetics*
D053628:Receptors, Thrombopoietin; D050799:STAT5 Transcription Factor; C082218:MPL protein, human; C507924:JAK2 protein, human; D053614:Janus Kinase 2