title: Does the presence of adefovir-resistant variants lead to failure of tenofovir monotherapy?
authors.forename: Katja
authors.initials: K
authors.lastname: Deterding
authors.forename: Michael P
authors.initials: MP
authors.lastname: Manns
authors.forename: Heiner
authors.initials: H
authors.lastname: Wedemeyer
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D024882:Drug Resistance, Viral / Q000235:genetics; D014644:Genetic Variation; D006515:Hepatitis B virus / Q000187:drug effects / Q000235:genetics; D019694:Hepatitis B, Chronic / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D063065:Organophosphonates / Q000627:therapeutic use*; D000068698:Tenofovir; D017211:Treatment Failure
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; C053001:adefovir; D000068698:Tenofovir; D000225:Adenine