title: Surgery for sinus of valsalva aneurysm: 27-year experience with 100 patients.
abstract: Sinus of Valsalva aneurysm is a rare anomaly. This study was designed to assess the long-term outcome of surgical repair of sinus of Valsalva aneurysm and factors influencing the prognosis. From August 1980 to August sinus of Valsalva aneurysm repair. Ventricular septal defect (42) and aortic regurgitation (34) were the most frequent coexisting anomalies. An approach via the involved chamber was used in 60 patients, aortotomy in 5, and a combined approach in 35. Either direct (43) or patch (57) closure was used to repair the defect. Aortic valve replacement was required in 14 patients, and 8 needed valvuloplasty. Eighty patients were followed up for 15.6 +/- 3.9 years. There were 3 hospital deaths and 2 late deaths. New York Heart Association functional class improved significantly after surgery. Actuarial survival was 94% at 10 years, and 90% at 15 years. Surgical treatment of sinus of Valsalva aneurysm is safe and effective, but late progressive aortic regurgitation is still a risk during long-term follow-up, and early aggressive measures are recommended.
authors.affiliation: Department of Cardiac Surgery, The First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China. yfheart@gmail.com
authors.forename: Fei
authors.initials: F
authors.lastname: Yan
authors.forename: Qiang
authors.initials: Q
authors.lastname: Huo
authors.forename: Jun
authors.initials: J
authors.lastname: Qiao
authors.forename: Vakeli
authors.initials: V
authors.lastname: Murat
authors.forename: Song-Feng
authors.initials: SF
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D001014:Aortic Aneurysm / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D001019:Aortic Rupture / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012850:Sinus of Valsalva / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects