Adjacent thoracic lymph node metastases originating from two separate primary cancers: case report.
Reported is an unusual case of adjacent thoracic lymph nodes demonstrating metastases from two different primary malignancies. A 51 year-old woman with a previous history of bilateral breast cancer underwent a radical gastro-oesophagectomy for adenocarcinoma of the lower third of the oesophagus. The resection specimen demonstrated breast and oesophageal metastases in adjacent thoracic lymph nodes. Mechanisms for this phenomenon, including the known local immune suppression on lymphoid cells by oesophageal carcinoma cells, are discussed.
El-Gendy
Khalid A
KA
Department of Surgery, Watford General Hospital, Vicarage Rd, Watford, WD18 0HB, Hertfordshire, UK.
Atkin
Gary K
GK
Department of Surgery, Watford General Hospital, Vicarage Rd, Watford, WD18 0HB, Hertfordshire, UK.
Brightwell
Robert E
RE
Department of Biosurgery and Surgical Technology, Imperial College London, London, UK.
Richman
Paul
P
Department of Histopathology, Mount Vernon Hospital, Rickmansworth Rd, Northwood, Middlesex, HA6 2RN, UK.
Livingstone
Jeremy I
JI
Department of Surgery, Watford General Hospital, Vicarage Rd, Watford, WD18 0HB, Hertfordshire, UK.