title: Influence of surface modification on the in vitro corrosion rate of magnesium alloy AZ31.
abstract: In recent years, magnesium alloys have been proposed as a new class of metallic bioabsorbable implant material. Unfortunately, the production of hydrogen gas and an increase in alkalinity are both by-products of the degradation process of these materials. This necessitates the development of magnesium alloys with controlled degradation rates. Furthermore, biocompatible coatings that can delay the onset of corrosion would ensure that the mechanical integrity of the implant remains intact in the early stages of healing. This article explores the influence of surface modification by biomimetic calcium phosphate coating, biodegradable polymer coatings, and acid etching on the corrosion rate of the AZ31 magnesium alloy in simulated body fluid. Our results indicate that all of these surface treatments have a positive impact on the corrosion rate of the material and that in the early stages of implantation it is possible to tailor the corrosion rate through an appropriate choice of surface treatment.
authors.affiliation: Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario P3E2C6, Canada. jgray@laurentian.ca
authors.forename: Joy E
authors.initials: JE
authors.lastname: Gray-Munro
authors.forename: Christine
authors.initials: C
authors.lastname: Seguin
authors.forename: Michael
authors.initials: M
authors.lastname: Strong
mesh_terms: D000143:Acids / Q000737:chemistry; D000497:Alloys / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003343:Corrosion; D008274:Magnesium / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000143:Acids; D000497:Alloys; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D011108:Polymers; C020243:calcium phosphate; D008274:Magnesium