title: [Hypophosphatemic osteomalacia].
abstract: Hypophosphatemic osteomalacia first presenting in adulthood is a rare disease. It is characterized by decreased serum phosphate, renal phosphate wasting, elevated alkaline phosphatase, and osteomalacia. The authors present a case with typical constellation of an oncogenic (tumor-induced) osteomalacia, the possible differential diagnosis, diagnostic evaluation, and complete healing after tumor resection. The new concepts of hereditary and acquired hypophosphatemic osteomalacia are discussed helping us understand this rare disease.
authors.affiliation: Endokrinologikum, Zentrum für Hormon- und Stoffwechselstörungen, Reproduktionsmedizin und Pränatale Medizin, Lornsenstrasse 4-6, Hamburg, Germany. catharina.bullmann@endokrinologikum.com
authors.forename: Catharina
authors.initials: C
authors.lastname: Bullmann
authors.forename: Georg
authors.initials: G
authors.lastname: Benker
authors.forename: Ulrich
authors.initials: U
authors.lastname: Rosien
authors.forename: Günther
authors.initials: G
authors.lastname: Delling
authors.forename: Heide
authors.initials: H
authors.lastname: Siggelkow
authors.forename: Heinrich Maria
authors.initials: HM
authors.lastname: Schulte
mesh_terms: D000328:Adult; D001706:Biopsy; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005346:Fibroblast Growth Factors / Q000097:blood; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D017674:Hypophosphatemia / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008684:Metatarsus; D010014:Osteolysis / Q000209:etiology; D010018:Osteomalacia / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D010281:Parathyroid Hormone / Q000097:blood; D011860:Radiography, Abdominal; D012272:Ribs / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D010281:Parathyroid Hormone; D005346:Fibroblast Growth Factors