Biotransformation of glabratephrin, a rare type of isoprenylated flavonoids, by Aspergillus niger.
Microbial transformation of glabratephrin, the major isolated compound from Tephrosia purpurea, afforded pseudosemiglabrin. The formation of the transformed compound seems to be performed via ring opening-closure of a five-membered ring causing transformation from a spiro into a fused system. The structure of the transformed compound was determined by comprehensive NMR studies, including DEPT, COSY, HMQC, NOE and MS.
Mohamed
Abou-El-Hamd H
AE
Department of Chemistry, Aswan-Faculty of Science, South Valley University, Aswan, Egypt. abuelhamd2002@yahoo.com
Khalafallah
Ali K
AK
Yousof
Afifi H
AH
D001234:Aspergillus niger / Q000378:metabolism*; D001711:Biotransformation; D002852:Chromatography, Ion Exchange; D005419:Flavonoids / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy
D005419:Flavonoids; C532409:glabratephrin