Effect of hyperprolactinemia during development in children and adolescents.
Increased levels of prolactin associated with some antipsychotic treatment can potentially lead to serious adverse events including gynecomastia, galactorrhea, oligomenorrhea, amenorrhea, and pituitary tumors. Clinicians may need to employ pharmacotherapeutic interventions such as reducing dosage, switching antipsychotics, or prescribing adjunctive agents to minimize or prevent these negative side effects and improve patients' outcomes.
Correll
Christoph U
CU
Department of Psychiatry, the Zucker Hillside Hospital, Glen Oaks.
D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002657:Child Development / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D011307:Drug Prescriptions; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000139:chemically induced / Q000517:prevention & control; D001523:Mental Disorders / Q000188:drug therapy*; D011627:Puberty / Q000502:physiology*
D014150:Antipsychotic Agents