Orbital hyperostosis following exenteration.
OBJECTIVE
To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients.


METHODS
Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed.


RESULTS
Postexenteration CT showed thickened orbital walls in all 3 cases. The histopathology revealed necrotic destruction of the trabeculae mixed with randomly distributed chronic inflammatory cells and fibrosis and inflamed overlying granulation tissue.


CONCLUSIONS
The delayed healing of the granulation tissue during secondary intention in these cases is quite likely the cause of chronic osteitis of the underlying orbital bone that, in turn, led to postoperative diffuse hyperostosis.
Fleming
James Chris
JC
Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee 38103, USA.
Linder
James S
JS
Karcioglu
Zeynel A
ZA
D018266:Adenocarcinoma, Sebaceous / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery*; D005142:Eyelid Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D015576:Hyperostosis / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology; D017233:Orbit Evisceration; D009916:Orbital Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D011183:Postoperative Complications; D014057:Tomography, X-Ray Computed