Marine drugs--macrolactins.
The increasing demands for new lead compounds in pharmaceutical and agrochemical industries have driven scientists to search for new bioactive natural products. Marine microorganisms are rich sources of novel, bioactive secondary metabolites, and have attracted much attention of chemists, pharmacologists, and molecular biologists. This mini-review mainly focuses on macrolactins, a group of 24-membered lactone marine natural products, aiming at giving an overview on their sources, structures, biological activities, as well as their potential medical applications.
Lu
Xiao-Ling
XL
Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, No. 800 Xiangyin Road, Shanghai 200433, P. R. China.
Xu
Qiang-Zhi
QZ
Liu
Xiao-Yu
XY
Cao
Xin
X
Ni
Kun-Yi
KY
Jiao
Bing-Hua
BH
D018942:Macrolides / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D008386:Marine Biology; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism*
D018942:Macrolides; D004364:Pharmaceutical Preparations