title: Giant, congenital folliculosebaceous cystic hamartoma: a case against a pathogenetic relationship with trichofolliculoma.
abstract: Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma consisting of dilated folliculosebaceous units invested in mesenchymal elements. These solitary lesions typically affect adults, have a predilection for the central face or scalp, and remain less than 1.5 cm in greatest dimension. Although giant FSCH variants have been documented, the congenital presentation of a giant FSCH stands in contrast to earlier views of its histogenetic relationship with trichofolliculoma. We describe a giant pedunculated FSCH arising from the posterior neck of a 9-month-old Hispanic male and discuss various aspects of this highly unusual case.
authors.affiliation: Department of Plastic Surgery, Baylor College of Medicine, Houston, TX 77030, USA. pdcole@bcm.tmc.edu
authors.forename: Patrick
authors.initials: P
authors.lastname: Cole
authors.forename: Yoav
authors.initials: Y
authors.lastname: Kaufman
authors.forename: Megan
authors.initials: M
authors.lastname: Dishop
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Hatef
authors.forename: Larry
authors.initials: L
authors.lastname: Hollier
mesh_terms: D018859:Hair Follicle / Q000473:pathology*; D006222:Hamartoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008648:Mesoderm / Q000473:pathology; D009333:Neck; D012878:Skin Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*