Sister Mary Joseph's nodule: Three case reports.
BACKGROUND
An umbilical metastatic lesion is called 'Sister Mary Joseph's nodule'. It is an uncommon clinical or radiographic finding, and it is rare as the first sign of a malignant disease.


METHODS
We report three cases of Sister Mary Joseph's nodule. In the three cases presented, the primary tumor was an adenocarcinona of the sigmoid colon, a carcinoma of the bladder, and an adenocarcinoma of the gallbladder, respectively.


CONCLUSIONS
The differential diagnosis of an umbilical lesion should always include metastatic disease apart from benign lesions and primary neoplasms.
Larentzakis
Andreas
A
1st Department of Propaedeutic Surgery, Hippokrateion General Hospital, Athens Medical School, University of Athens, Q, Sofias 114 av,, 11527, Athens, Greece. alarentz@med.uoa.gr.
Theodorou
Dimitrios
D
Fili
Klio
K
Manataki
Anna
A
Bizimi
Vasiliki
V
Tibishrani
Michael
M
Katsaragakis
Stylianos
S