title: Porous-coated femoral components with or without hydroxyapatite in primary uncemented total hip arthroplasty: a systematic review of randomized controlled trials.
abstract: The purpose of this systematic review was to determine the clinical and radiologic benefit of hydroxyapatite coating in uncemented primary total hip arthroplasty. A database of Medline articles published up to September 2007 was compiled and screened. Eight studies involving 857 patients were included in the review. Pooled analysis for Harris hip score as a clinical outcome measure demonstrated no advantage of the hydroxyapatite coating (WMD: 1.49, P = 0.44). Radiologically, both groups showed equal presence of endosteal bone ingrowth (RR: 1.04, P = 0.66) and radioactive lines (RR: 1.02, P = 0.74) in the surface area of the prosthesis. This meta-analysis demonstrates neither clinical nor radiologic benefits on the application of a hydroxyapatite coating on a femoral component in uncemented primary total hip arthroplasty.
authors.affiliation: Department of Orthopedic Surgery and Traumatology, Isala Clinics, Zwolle, The Netherlands. j.h.m.goosen@isala.nl
authors.forename: J H M
authors.initials: JH
authors.lastname: Goosen
authors.forename: A J
authors.initials: AJ
authors.lastname: Kums
authors.forename: B J
authors.initials: BJ
authors.lastname: Kollen
authors.forename: C C P M
authors.initials: CC
authors.lastname: Verheyen
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation / Q000379:methods*; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002484:Cementation; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011859:Radiography; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D017886:Durapatite