[Clinical study on Shen Shuai Fang in treating chronic renal failure].
OBJECTIVE
To explore the effect of Shen Shuai Fang in treating Chronic Renal Failure (CRF) of deficiency of spleen and kidney with turbid damp and blood stagnation symptom.


METHODS
125 patients with CRF of deficiency of spleen and kidney with turbid damp and blood stagnation symptom were randomly divided into two groups, 75 patients in treatment group were treated with Shen Shuai Fang adding western medicine and the other patients in control group were treated only with western medicine. We observed the effect and indexes change including renal function, Hb, proteinuria, lipid before and after treatment.


RESULTS
After six months' treatment, the general effective rate in treatment group was 77.33%, which was higher than that in control group obviously (44.00%, P < 0.01). So treatment group was obviously better than control group on decreasing proteinuria, improving renal function, increasing Hb, ameliorating lipid metabolism (P < 0.05 or P < 0.01).


CONCLUSIONS
Shen Shuai Fang is effective to treat CRF of deficiency of spleen and kidney with turbid damp and blood stagnation symptom.
Wu
Xin-Lin
XL
The First Affiliated Hospital of Sun Yet-sen University, Guangzhou 510080, China.
Li
Zhi-Jian
ZJ
Zhang
Wei-Jun
WJ
Ao
Qin-Xing
QX
Xu
Yuan-Wen
YW
D000293:Adolescent; D000328:Adult; D000368:Aged; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy* / Q000473:pathology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D017257:Ramipril / Q000627:therapeutic use; D016896:Treatment Outcome; D016710:Yin Deficiency / Q000188:drug therapy; D055815:Young Adult
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D017257:Ramipril