title: A case of primary hepatic non-Hodgkin's lymphoma with chronic hepatitis C.
abstract: We report a case of primary hepatic non-Hodgkin's lymphoma in a 67-year-old man with chronic hepatitis C. Laboratory data revealed slightly elevated liver function parameters and positive for hepatitis C virus (HCV) antibody. Abdominal ultrasonography showed hypoechoic lesions approximately 5 mm in diameter in the whole liver. Magnetic resonance imaging showed that the tumors were isointense in relationship to the liver on T(1)-weighted images but were slightly hyperintense on T(2)-weighted images. Under a clinical diagnosis of liver tumor, liver biopsy was performed. Histological examination confirmed a diagnosis of non-Hodgkin's diffuse large B-cell lymphoma, and the immunophenotype was identified to be the germinal cell type.
authors.affiliation: Department of Internal Medicine, Kitasato Institute Medical Center Hospital, 6-100 Arai, Kitamoto, Saitama 364-8501, Japan. kaneko-f@insti.kitasato-u.ac.jp
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Kaneko
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Yokomori
authors.forename: Aya
authors.initials: A
authors.lastname: Sato
authors.forename: Hajime
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Kumiko
authors.initials: K
authors.lastname: Tahara
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Sekiguchi
authors.forename: Shigehisa
authors.initials: S
authors.lastname: Mori
authors.forename: Tadashi
authors.initials: T
authors.lastname: Motoori
authors.forename: Hirobumi
authors.initials: H
authors.lastname: Kondo
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hibi
mesh_terms: D000368:Aged; D019698:Hepatitis C, Chronic / Q000150:complications / Q000473:pathology; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000821:virology; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged