[Antibody response after immunization with a Salmonella Typhimurium live vaccine in dependence on the way of application].
In Germany now, the recognition of Salmonella infections in pig herds is based on three different commercial tests detecting antibodies against Salmonella-derived lipopolysaccharide (LPS). However, a serious disadvantage of these tests, used so far, is the restricted detection of antibodies belonging predominantly to the immunoglobulin class g (IgG). Therefore, a new test was developed to detect three Ig classes (IgM, IgG and IgA). Different constellations between the three Ig classes allow the evaluation of the current infection status of each pig. Under field conditions, this was proved in three different vaccination trials using a commercial Salmonella Typhimurium live vaccine.
Trepnau
Daniela
D
Labor Diagnostik GmbH Leipzig, Leipzig.
Ulrich
Evelyn
E
Uhlig
Reinhard
R
Lindner
Thomas
T
Selbitz
Hans-Joachim
HJ
Rösler
Uwe
U
Gabert
Jörg
J
Bergfeld
Uwe
U
Fehlhaber
Karsten
K
Brabetz
Werner
W
Lehmann
Jörg
J
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000918:Antibody Specificity; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D011897:Random Allocation; D012481:Salmonella Infections, Animal / Q000097:blood / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014613:Vaccines, Attenuated
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014613:Vaccines, Attenuated