Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand.
Two new bis(benzimidazole)aryl derivatives have been prepared and one of them has been shown to induce and stabilize formation of a G-quadruplex.
Li
Guorui
G
College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan, 430072, People's Republic of China.
Huang
Jing
J
Zhang
Ming
M
Zhou
Yangyang
Y
Zhang
Dan
D
Wu
Zhiguo
Z
Wang
Shaoru
S
Weng
Xiaocheng
X
Zhou
Xiang
X
Yang
Guangfu
G
D001483:Base Sequence; D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D054856:G-Quadruplexes / Q000187:drug effects*; D008024:Ligands; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
C500137:2,6-bis(benzimidazol-2-yl)pyridine; D001562:Benzimidazoles; D008024:Ligands; D011725:Pyridines; D004247:DNA