title: [Streptococcus pneumoniae endocarditis diagnosed with polymerase chain reaction].
abstract: A 60-year old man was admitted with sepsis and meningitis of unknown aetiology. Underlying aortic valve endocarditis was diagnosed by echocardiography and severe insufficiency led to aortic valve replacement. Application of broad-range PCR to cusp tissue revealed a DNA product, and a diagnosis of Streptococcus pneumoniae endocarditis was obtained by DNA sequencing.
authors.affiliation: Kardiologisk Afdeling P, Gentofte Hospital, DK-2900 Hellerup. nibru@geh.regionh.dk.
authors.forename: Rasmus Vedby
authors.initials: RV
authors.lastname: Rasmussen
authors.forename: Michael
authors.initials: M
authors.lastname: Kemp
authors.forename: Jette M
authors.initials: JM
authors.lastname: Bangsborg
authors.forename: Anne Vinther
authors.initials: AV
authors.lastname: Kjerulf
authors.forename: John Brochorst
authors.initials: JB
authors.lastname: Christensen
authors.forename: Niels Eske
authors.initials: NE
authors.lastname: Bruun
mesh_terms: D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D013296:Streptococcus pneumoniae / Q000235:genetics / Q000302:isolation & purification; D014463:Ultrasonography