A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine.
A convergent and flexible synthesis of substituted triphenylenes, azatriphenylenes, and the cytotoxic alkaloids dehydrotylophorine and tylophorine has been developed.
McIver
Andrew
A
North Carolina State University, Department of Chemistry, Raleigh, NC 27695-8204, USA.
Young
Douglas D
DD
Deiters
Alexander
A
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D002911:Chrysenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D003500:Cyclization; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D008872:Microwaves; D015394:Molecular Structure; D010616:Phenanthrenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D013237:Stereoisomerism
D000470:Alkaloids; D001372:Aza Compounds; D002911:Chrysenes; D007212:Indolizines; D010616:Phenanthrenes; C533582:azatriphenylene; C009590:triphenylene; C004218:tylophorine