title: Voiding symptoms and urodynamic findings in patients with modified ileal neobladde.
abstract: The aim of our study was to find the cause of urinary incontinence and voiding dysfunction in patients undergoing radical cystectomy and orthotopic bladder replacement with modified ileal neobladder (Reddy). Twenty-eight incontinent patients (operated on between 1988 and 2004) were involved in our examination. Based on the complaints of the patients, continence status was evaluated and divided into two groups: group I: partially incontinent (only night-time incontinence) n = 11 (39.3%) and group II: totally incontinent (night-time and daytime incontinence) n = 17 (60.7%). Detailed urodynamic examination (enterocystometry and urethral pressure profile) in addition to involuntary neobladder contractions and capacity detection were carried out on all patients. Furthermore resting pressure and maximal voluntary contraction ability of the sphincter were determined and statistically analyzed in both groups. Significant difference was noticed in resting pressure and maximal voluntary contraction ability of the sphincter among the partially incontinent and totally incontinent patients. Frequency, intensity and duration of involuntary neobladder contractions also showed significant differences between the two groups. Incontinence of neobladder depends not only on the destruction of resting and contraction capability of the urethral sphincter, but also on the presence or absence of involuntary contractions in the wall of the neobladder and decreased capacity of the neobladder.
authors.affiliation: Semmelweis University, Budapest, Hungary. attilakeszthelyi@hotmail.com
authors.forename: Attila
authors.initials: A
authors.lastname: Keszthelyi
authors.forename: Attila
authors.initials: A
authors.lastname: Majoros
authors.forename: Péter
authors.initials: P
authors.lastname: Nyirády
authors.forename: Peter
authors.initials: P
authors.lastname: Mayer
authors.forename: Dietmar
authors.initials: D
authors.lastname: Bach
authors.forename: Imre
authors.initials: I
authors.lastname: Romics
mesh_terms: D000368:Aged; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D011183:Postoperative Complications / Q000503:physiopathology*; D001749:Urinary Bladder Neoplasms / Q000601:surgery; D014549:Urinary Incontinence / Q000209:etiology; D016476:Urinary Reservoirs, Continent / Q000009:adverse effects* / Q000502:physiology; D014554:Urination / Q000502:physiology*; D014563:Urodynamics / Q000502:physiology*