Primary intratesticular spindle cell tumors: interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor.
Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special techniques are needed. The present study reports 2 unusual cases of primary intratesticular tumors showing a striking morphology, characterized by spindle to stellate cells in a lymphoid background. The diagnosis of interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor was established in the 2 cases, and their probable origin in cells of the accessory immune system is discussed. Although both tumors share similar histological features, their immunohistochemical profiles were decisive for a definitive diagnosis.
Nistal
Manuel
M
Department of Pathology, Hospital La Paz, Madrid, Spain.
Gonzalez-Peramato
Pilar
P
Serrano
Alvaro
A
Reyes-Mugica
Miguel
M
Cajaiba
Mariana M
MM
D000328:Adult; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009919:Orchiectomy; D012509:Sarcoma / Q000473:pathology* / Q000601:surgery; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery