title: [Optimization for formulation matrix proportion of xiangyu cataplasm by uniform design].
abstract: OBJECTIVE
  To optimize the matrix formulation of cataplasm used to cure infantile diarrhea.
  
  
  METHODS
  The optimum proportion of matrix for the preparation technology process of cataplasm was selected by uniform design and SPSS regression analysis. A check-up for adhibition , peeling strength, nonflowing, content of cream was founded.
  
  
  RESULTS
  The best matrix's prescription gelatin: CMC-Na: PANA: kaolin: aluminum trichloride: citric acid: PVP K-30: PEG400: trimethylene glycol: tween-80 was 0.25 : 0.1 : 0.2 : 1.5 : 0.4 : 0.6 : 0.8 : 2 : 1 : 0.5.
  
  
  CONCLUSIONS
  The preparation technique of cataplasm is feasible, and its quality is steerable, it is a safe and effective transdermal-drug delivery system.
authors.affiliation: Wuhan University of Technology, Wuhan 430070, China. xuke_coco@163.com
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.forename: Pei-Hu
authors.initials: PH
authors.lastname: Xu
authors.forename: Xue-Qiong
authors.initials: XQ
authors.lastname: Zhang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000268:Adhesiveness; D000704:Analysis of Variance; D001672:Biocompatible Materials / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004338:Drug Combinations; D016503:Drug Delivery Systems; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000378:metabolism; D005780:Gelatin / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012869:Skin Absorption; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005780:Gelatin