title: [Bluetongue disease in Swiss sheep breeds: clinical signs after experimental infection with bluetongue virus serotype 8].
abstract: Clinical disease of bluetongue (BT) in sheep may differ depending on breed, age and immunity of infected sheep and may also vary between serotype and strain of BT virus (BTV). Since there are no data available on the susceptibility of Swiss sheep breeds for BT, we performed experimental infection of the 4 most common Swiss sheep breeds and the highly susceptible Poll Dorset sheep with the BTV serotype 8 (BTV-8) circulating in Northern Europe since 2006. Clinical signs were assessed regarding severity, localisation, progression and time point of their appearance. The results clearly show that the Swiss sheep breeds investigated were susceptible to BTV-8 infection. They developed moderate, BT-characteristic symptoms, which were similar to those observed in Poll Dorset sheep. Regardless of breed, the majority of infected animals showed fever, swelling of the head as well as erosions of the mouth and subcutaneous haemorrhages.
authors.affiliation: Institut für Viruskrankheiten und Immunprophylaxe (IVI), Mittelhäusern, Schweiz.
authors.forename: G
authors.initials: G
authors.lastname: Worwa
authors.forename: B
authors.initials: B
authors.lastname: Thür
authors.forename: C
authors.initials: C
authors.lastname: Griot
authors.forename: M
authors.initials: M
authors.lastname: Hofmann
authors.forename: J N
authors.initials: JN
authors.lastname: MacLachlan
authors.forename: V
authors.initials: V
authors.lastname: Chaignat
mesh_terms: D000818:Animals; D001819:Bluetongue / Q000473:pathology* / Q000821:virology*; D001820:Bluetongue virus / Q000145:classification* / Q000472:pathogenicity; D001947:Breeding; D004198:Disease Susceptibility / Q000662:veterinary; D005260:Female; D008297:Male; D012703:Serotyping / Q000662:veterinary; D012720:Severity of Illness Index; D012756:Sheep; D013557:Switzerland