title: Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes.
abstract: A high yielding, batch mode synthesis of diaryl ethers and sulfides by an S(N)Ar fluoride-mediated process in scCO(2) has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous flow process, with high conversions.
authors.affiliation: Department of Chemistry, University of Cambridge, Cambridge, UK CB2 1EW.
authors.forename: Jin-Kyun
authors.initials: JK
authors.lastname: Lee
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Fuchter
authors.forename: Rachel M
authors.initials: RM
authors.lastname: Williamson
authors.forename: Gary A
authors.initials: GA
authors.lastname: Leeke
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Bush
authors.forename: Ian F
authors.initials: IF
authors.lastname: McConvey
authors.forename: Simon
authors.initials: S
authors.lastname: Saubern
authors.forename: John H
authors.initials: JH
authors.lastname: Ryan
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Holmes
mesh_terms: D002245:Carbon Dioxide / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D025924:Chromatography, Supercritical Fluid; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D005464:Fluorobenzenes / Q000737:chemistry; D015394:Molecular Structure; D011312:Pressure; D013440:Sulfides / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D004987:Ethers; D005464:Fluorobenzenes; D013440:Sulfides; D002245:Carbon Dioxide