[Study on the solubilization of O/W microemulsion for volatile oil].
OBJECTIVE
To study the solubilization of O/W microemulsion system for volatile oil.


METHODS
Pseudo-ternary phase diagrams were prepared by using the method of titration, then investigating the solubilization of microemulsion system for different kind of volatile oil was investigated with the diagrams, and the effect of the formulation of microemulsion on the solubilization of Citrus sinensis oil were studied.


RESULTS
Kinds of volatile oil have an accelerated solubility in the microemulsion system. The species and dosage of oil phase and surfactant could influence the solubilization of microemulsion on Citrus sinensis oil.


CONCLUSIONS
It is recommended to select a new method to solve the stabilization of volatile oil in the liquid preparation by the solubilization of suitable formulation of microemulsion.
Yi
Hong
H
Institute of Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijing 100700, China.
Yang
Hua
H
Deng
Mao
M
D004365:Drugs, Chinese Herbal / Q000737:chemistry; D004655:Emulsions; D009822:Oils, Volatile / Q000737:chemistry*; D012995:Solubility / Q000187:drug effects; D013501:Surface-Active Agents / Q000494:pharmacology; D014867:Water / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D004655:Emulsions; D009822:Oils, Volatile; D013501:Surface-Active Agents; D014867:Water