title: Malignant lymphoma of the tonsil in a patient with Behçet's disease.
abstract: Several connective tissue diseases such as rheumatoid arthritis and polymyositis are associated with cancer. In contrast, cancer is rarely reported in patients with Behçet disease. We report a case of lymphoma during the course of Behçet disease. Etiopathogenic factors are discussed. A 46-year-old man with a 14-year history of Behçet disease was diagnosed with non-Hodgkin malignant lymphoma of the right tonsil. He met international criteria for Behçet disease, which manifested as refractory oral ulcers requiring dapsone treatment. He achieved a complete remission of the lymphoma after three chemotherapy courses and local radiation therapy (45 Gy). At last follow-up 4 years later, he was still in complete remission.
authors.affiliation: Hôpital la Rabtan, Département de rhumatologie, Tunis, Tunisia. yesminti@yahoo.fr
authors.forename: Leila
authors.initials: L
authors.lastname: Souabni
authors.forename: Mohamed
authors.initials: M
authors.lastname: Elleuch
authors.forename: Chiraz
authors.initials: C
authors.lastname: Amira
authors.forename: Slaheddine
authors.initials: S
authors.lastname: Sellami
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D001528:Behcet Syndrome / Q000150:complications / Q000473:pathology*; D003131:Combined Modality Therapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D014067:Tonsillar Neoplasms / Q000150:complications / Q000473:pathology*