title: Comparison and reproducibility of corneal thickness and curvature readings obtained by the Galilei and the Orbscan II analysis systems.
abstract: OBJECTIVE
  To compare central corneal thickness (CCT) and keratometry readings using the Galilei dual Scheimpflug analyzer, the Orbscan II anterior segment analysis system, and the Sonogage ultrasound (US) pachymeter.
  
  
  METHODS
  Lucerne Eye Clinic, Cantonal Hospital, Lucerne, Switzerland.
  
  
  METHODS
  In a prospective single-center study, 85 eyes of 45 healthy volunteers were examined with the Orbscan II and Galilei systems in random order followed by Sonogage US pachymetry. The CCT and keratometry measurements were compared using a paired t test. To assess the intraobserver and interobserver reproducibility of the 2 keratometers, 9 volunteers were examined 3 times by 4 independent observers and the intraclass correlation coefficient (ICC) was calculated.
  
  
  RESULTS
  The mean CCT was 551.7 microm+/-36.6 (SD) with the Galilei, 554.8+/-45.1 microm with the Orbscan II, and 558.5+/-38.4 microm with the Sonogage. The CCT readings of the Galilei and Orbscan II did not differ significantly (P= .12). The mean keratometry readings with the Galilei and Orbscan II were similar, although both the steep (Ks) and flat (Kf) axes tended to be flatter with the Galilei system. The ICCs for CCT, Kf, and Ks were high with both keratometers (0.98, 0.97, 0.84 for Galilei and 0.97, 0.96, 0.95 for Orbscan II, respectively), indicating that variation in measurements was mainly due to true subject-to-subject variation rather than observer error.
  
  
  CONCLUSIONS
  Keratometry and pachymetry readings with the Galilei and Orbscan II systems showed good concordance and high reproducibility, which would allow the examinations to be delegated to nonmedical personnel.
authors.affiliation: Department of Ophthalmology, Cantonal Hospital Lucerne, Luzern, Switzerland.
authors.forename: Nardine
authors.initials: N
authors.lastname: Menassa
authors.forename: Claude
authors.initials: C
authors.lastname: Kaufmann
authors.forename: Michael
authors.initials: M
authors.lastname: Goggin
authors.forename: Oliver M
authors.initials: OM
authors.lastname: Job
authors.forename: Lucas M
authors.initials: LM
authors.lastname: Bachmann
authors.forename: Michael A
authors.initials: MA
authors.lastname: Thiel
mesh_terms: D000328:Adult; D001837:Body Weights and Measures; D003315:Cornea / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D019781:Corneal Topography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011446:Prospective Studies; D015203:Reproducibility of Results; D014463:Ultrasonography