A modular "toolbox" approach to flexible branched multimacrocyclic hosts as precursors for multiply interlocked architectures.
Tetralactam macrocycles can be functionalized by a variety of cross-coupling reactions. A modular "toolbox" strategy is presented that allows 1) several tetralactam macrocycles to be covalently connected with each other or with a central spacer, 2) the macrocycles to be substituted with or connected to different chromophores, and 3) metal-coordination sites to be attached to the macrocycles. With this approach a series of different oligo-macrocyclic hosts was obtained with great structural diversity and enormous potential for further functionalization. Rotaxanes made on the basis of these macrocycles have been synthesized to demonstrate their utility in building more complex supramolecular architectures.
Baytekin
Bilge
B
Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
Zhu
Sascha S
SS
Brusilowskij
Boris
B
Illigen
Jens
J
Ranta
Jenni
J
Huuskonen
Juhani
J
Russo
Luca
L
Rissanen
Kari
K
Kaufmann
Lena
L
Schalley
Christoph A
CA
D018360:Crystallography, X-Ray; D003500:Cyclization; D007769:Lactams / Q000138:chemical synthesis* / Q000737:chemistry; D008163:Luminescent Measurements; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D043862:Rotaxanes / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
D007769:Lactams; D047028:Macrocyclic Compounds; D043862:Rotaxanes; C535036:tetralactam macrocycle