Copper-catalyzed one-pot multicomponent coupling reaction of phenols, amides, and 4-bromphenyl iodide.
An efficient copper-catalyzed multicomponent reaction of phenols, amides, and 4-bromphenyl iodide was developed that uses commercially available N,N-dimethylglycine as the ligand. This multicomponent reaction proceeds in moderate to good yields for a range of phenols and amides. The simple experimental procedure and high levels of functional group compatibility make this method attractive for applications on pesticides.
Chen
Wenming
W
Department of Chemistry and Materials, Sichuan Normal University, Chengdu 610066, PR China.
Li
Jianjun
J
Fang
Dongmei
D
Feng
Chun
C
Zhang
Chenggang
C
D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*
C533372:4-bromphenyl iodide; D000577:Amides; D006846:Hydrocarbons, Halogenated; D007454:Iodides; D008024:Ligands; D010636:Phenols; D003300:Copper