Cystic white-matter changes in childhood Wilson's disease.
Altered signals in magnetic resonance imaging are present in most symptomatic patients with neurologic manifestations of Wilson's disease. The changes primarily involve the basal ganglia, but they can be diverse and can involve a host of other structures. We describe a 12-year-old boy with Wilson's disease who manifested prominent white-matter cystic changes. These changes can cause diagnostic confusion, and may also present prognostic implications.
Sankhyan
Naveen
N
Division of Pediatric Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. nsankhyan@rediffmail.com
Sharma
Suvasini
S
Kalra
Veena
V
Garg
Ajay
A
Balkrishnan
Pralahad
P
D001921:Brain / Q000473:pathology*; D002648:Child; D003560:Cysts / Q000473:pathology*; D003937:Diagnosis, Differential; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male