title: Mobility limitations in persons with psychotic disorder: findings from a population-based survey.
abstract: BACKGROUND
  There are few reports on mobility limitations in persons with psychotic disorder although restrictions in mobility may aggravate the general functional limitations of these patients. Our aim was to investigate mobility limitations among subjects with psychotic disorder in a general population-based sample.
  
  
  METHODS
  A nationally representative sample of 6,927 persons aged 30 and older self-reported mobility limitations in an interview and was examined in performance tests. Diagnostic assessment of DSM-IV psychotic disorders combined SCID interview and case note data. Lifetime-ever diagnoses of psychotic disorder were classified into schizophrenia, other nonaffective psychotic disorders and affective psychoses.
  
  
  RESULTS
  Self-reported mobility limitations were highly prevalent in persons with schizophrenia and other nonaffective psychosis, but not in the affective psychosis group. After adjusting for age and sex, persons with schizophrenia and other nonaffective psychoses but not affective psychoses had significantly increased odds of having both self-reported and test-based mobility limitations as well as weak muscle strength. Schizophrenia remained an independent predictor of mobility limitations even after controlling for lifestyle-related factors and chronic medical conditions. Among persons with nonaffective psychoses, higher levels of negative symptoms predicted mobility limitations.
  
  
  CONCLUSIONS
  Self-reported mobility limitations are prevalent already at a young age in persons with schizophrenia and other nonaffective psychotic disorders, and among older persons with these disorders both self-reported limitations and measured performance tests show lower capacity in mobility. Difficulties in mobility are associated with negative symptoms. Mental health care professionals should pay attention to mobility limitations in persons with psychotic disorder.
authors.affiliation: Dept. of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, Helsinki 00300, Finland. satu.viertio@ktl.fi
authors.forename: Satu
authors.initials: S
authors.lastname: Viertiö
authors.forename: Päivi
authors.initials: P
authors.lastname: Sainio
authors.forename: Seppo
authors.initials: S
authors.lastname: Koskinen
authors.forename: Jonna
authors.initials: J
authors.lastname: Perälä
authors.forename: Samuli I
authors.initials: SI
authors.lastname: Saarni
authors.forename: Marja
authors.initials: M
authors.lastname: Sihvonen
authors.forename: Jouko
authors.initials: J
authors.lastname: Lönnqvist
authors.forename: Jaana
authors.initials: J
authors.lastname: Suvisaari
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003625:Data Collection; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D051346:Mobility Limitation; D011618:Psychotic Disorders / Q000453:epidemiology / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology