One hit, two outcomes for VHL-mediated tumorigenesis.
Behrens
Jürgen
J
Jürgen Behrens is at the Nikolaus-Fiebiger Center for Molecular Medicine, University Erlangen, Glückstr. 6, 91341 Erlangen, Germany. jbehrens@molmed.uni-erlangen.de
D000818:Animals; D018398:Homeodomain Proteins / Q000378:metabolism*; D006801:Humans; D051793:Hypoxia-Inducible Factor 1 / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D011485:Protein Binding; D014158:Transcription, Genetic; D025521:Tumor Suppressor Proteins / Q000378:metabolism*; D051794:Von Hippel-Lindau Tumor Suppressor Protein / Q000378:metabolism*; D051153:Wnt Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D051176:beta Catenin / Q000378:metabolism*
D018398:Homeodomain Proteins; D051793:Hypoxia-Inducible Factor 1; C469360:JADE1 protein, human; D025521:Tumor Suppressor Proteins; D051153:Wnt Proteins; D051176:beta Catenin; D051794:Von Hippel-Lindau Tumor Suppressor Protein