title: Primary intratesticular spindle cell tumors: interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor.
abstract: Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special techniques are needed. The present study reports 2 unusual cases of primary intratesticular tumors showing a striking morphology, characterized by spindle to stellate cells in a lymphoid background. The diagnosis of interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor was established in the 2 cases, and their probable origin in cells of the accessory immune system is discussed. Although both tumors share similar histological features, their immunohistochemical profiles were decisive for a definitive diagnosis.
authors.affiliation: Department of Pathology, Hospital La Paz, Madrid, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Nistal
authors.forename: Pilar
authors.initials: P
authors.lastname: Gonzalez-Peramato
authors.forename: Alvaro
authors.initials: A
authors.lastname: Serrano
authors.forename: Miguel
authors.initials: M
authors.lastname: Reyes-Mugica
authors.forename: Mariana M
authors.initials: MM
authors.lastname: Cajaiba
mesh_terms: D000328:Adult; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009919:Orchiectomy; D012509:Sarcoma / Q000473:pathology* / Q000601:surgery; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery