Decreased tuberculosis incidence and declining clustered case rates, Madrid.
To determine effect of recent tuberculosis transmission rates on incidence rates, we conducted 2 prospective population-based molecular epidemiologic studies in Madrid during 1997-1999 (4% immigrants) and 2002-2004 (14.9% immigrants). Case rates decreased in association with declining clustered case rates among Spanish-born persons. New strains were introduced through immigration.
Iñigo
Jesús
J
Consejería de Sanidad Comunidad de Madrid, Madrid, Spain.
Arce
Araceli
A
Palenque
Elia
E
García de Viedma
Darío
D
Chaves
Fernando
F
D000328:Adult; D000368:Aged; D016000:Cluster Analysis; D004641:Emigration and Immigration; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D014505:Urban Population