title: [Efficacy and tolerability of the combined therapy with mesipol and baclosan in chronic recurrent vertebrogenic pain syndrome].
abstract: An article highlights the pathogenetic aspects of treatment of reflex pain syndromes in the degenerative-dystrophic spinal lesions. Attention is focused on a rational combination of medications that may shorten the duration of analgesic and anti-inflammatory therapy to prevent the development of side-effects caused by non-steroid anti-inflammatory medications. The results of own research of analgesic efficacy and tolerability of treatment in 50 patients with chronic skeletal-muscle pain syndromes in the state of exacerbation assigned to the combination of a non-steroid anti-inflammatory medication mesipol (meloxicam) with a central myorelaxant baclosan (baclofen) are discussed. It was found the positive effect of therapy not only on pain syndrome but on comorbid symptoms as well.
authors.forename: A N
authors.initials: AN
authors.lastname: Karneev
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Solov'eva
authors.forename: A I
authors.initials: AI
authors.lastname: Fedin
mesh_terms: D001416:Back Pain / Q000188:drug therapy*; D001418:Baclofen / Q000008:administration & dosage / Q000627:therapeutic use*; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D000077239:Meloxicam; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D013577:Syndrome; D013843:Thiazines / Q000008:administration & dosage / Q000627:therapeutic use*; D013844:Thiazoles / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D016861:Cyclooxygenase Inhibitors; D009125:Muscle Relaxants, Central; D013843:Thiazines; D013844:Thiazoles; D001418:Baclofen; D000077239:Meloxicam