title: Nipple-sparing mastectomy--initial experience at a tertiary center.
abstract: BACKGROUND
  Nipple-sparing mastectomy (NSM) combines skin-sparing mastectomy with preservation of the nipple-areolar dermis and intraoperative pathologic assessment of the nipple core. We evaluated our initial experience with NSM in terms of clinical outcomes.
  
  
  METHODS
  An Institutional Review Board-approved retrospective review of patients undergoing NSM between November 2005 and June 2007 was performed.
  
  
  RESULTS
  Eighteen NSM and two areola-sparing mastectomies were performed. Indications for surgery were invasive cancer (n = 4), ductal carcinoma in situ (DCIS) (n = 5), pseudoangiomatous stromal hyperplasia (n = 3), and risk reduction (n = 8). The average distance of tumor from the nipple on imaging was 4.8 cm (range 4 to 5.7). Nipple cores were all benign, and 2 patients developed self-limited superficial desquamation of the nipple. At a mean follow up of 10.8 months, all nipple-areolar complexes were intact, and there were no local or systemic recurrences.
  
  
  CONCLUSIONS
  NSM can be successfully achieved with low morbidity in appropriately selected patients.
authors.affiliation: Department of Surgery, Mayo Clinic, Rochester, MN, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Sookhan
authors.forename: Judy C
authors.initials: JC
authors.lastname: Boughey
authors.forename: Molly F
authors.initials: MF
authors.lastname: Walsh
authors.forename: Amy C
authors.initials: AC
authors.lastname: Degnim
mesh_terms: D000328:Adult; D001828:Body Image; D001943:Breast Neoplasms / Q000601:surgery*; D004954:Esthetics; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009558:Nipples / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome