title: [Multi-centered clinical trial of Fufang Xuanju capsule for oligoasthenospermia].
abstract: OBJECTIVE
  To observe the efficacy of Fufang Xuanju Capsule in the treatment of oligoasthenospermia.
  
  
  METHODS
  Using a multi-centered, open and self-controlled clinical trial, we treated 120 patients with oligoasthenospermia, with Fufang Xuanju Capsule for 12 weeks, and evaluated the efficacy of the capsule with sperm concentration and vitality (a + b) as the primary and the number of grade a sperm, sperm motility (a + b + c) and semen volume as the secondary therapeutic indexes.
  
  
  RESULTS
  A total of 107 patients accomplished the clinical trial. Compared with pre-treatment, sperm density, vitality and motility were significantly improved after 4, 8 and 12 weeks of Fufang Xuanju treatment (P < 0.01). At 12 weeks, sperm concentration was increased by 63.28%, with 73 cases (68.22%) restored to normal, sperm vitality by 63. 17%, with 39 (36.45%) restored to normal, sperm motility by 44.36%, with 77 (71.96%) restored to normal, and the semen volume by 18.13%.
  
  
  CONCLUSIONS
  Fufang Xuanju Capsule can evidently improve the seminal quality of oligoasthenospermia patients.
authors.affiliation: Department of Urology, The Third Hospital of Peking University, Beijing 100083, China. jianghui55@163.com
authors.forename: Hui
authors.initials: H
authors.lastname: Jiang
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Shang
authors.forename: Jun
authors.initials: J
authors.lastname: Guo
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.forename: Lian-Ming
authors.initials: LM
authors.lastname: Zhao
authors.forename: Yong
authors.initials: Y
authors.lastname: Shao
authors.forename: Ping
authors.initials: P
authors.lastname: Ping
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Huang
authors.forename: Ji-Chuan
authors.initials: JC
authors.lastname: Zhu
mesh_terms: D000328:Adult; D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D008517:Phytotherapy; D013076:Sperm Count; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; C539008:fufang xuanju