title: [Effects of the needling method for regulating kidney and smoothing liver on endocrine and immune functions in the patient with hyperplasia of mammary glands].
abstract: OBJECTIVE
  To probe into a better acupoint association for treatment of hyperplasia of mammary glands and the mechanism.
  
  
  METHODS
  Two hundred cases were randomly divided into a regulating kidney and smoothing liver needling group, a routine acupuncture group and a Chinese medicine group. The regulating kidney and smoot hing liver needling group were treated with acupuncture at Shenshu (BL 23), Mingmen (GV 4), Fengfu (GV 16), Lingxu (KI 24), Shenfeng (KI 23), Bulang (KI 22), Qimen (LR 14), etc. and the routine acupuncture group with acupuncture at Zusanli (ST 36), Tanzhong (CV 17), Ganshu (BL 18), Rugen (ST 18), Neiguan (PC 6), Qimen (LR 14), once daily; and the Chinese medicine group with oral administration of Rupixiao tablet, 6 tablets each time, thrice each day. After they were treated for 2 menstrual cycles, the therapeutic effects and changes of E2, PRL, P, CD3+, CD4+ and CD8+ were observed.
  
  
  RESULTS
  The clinical therapeutic effect and the total effective rate for TCM syndromes were 92.0% and 94.0% in the regulating kidney and smoothing liver needling group, 86.0% and 88.0% in the routine acupuncture group and 78.0% and 84.0% in the Chinese medicine group, with a significant difference among the 3 groups, the former being better than the other two groups; after treatment, serum PRL, P, P/E2 significantly improved in all the 3 groups (P < 0.05) and the regulating kidney and smoothing liver needling group was better than other two groups in decreasing PRL and increasing P, P/E2 (P < 0.05); and E2, CD8+, CD4+/CD8+ significantly improved in the regulating kidney and smoothing liver needling group and the routine acupuncture group, the former being better than the later in decreasing E2 (P < 0.05).
  
  
  CONCLUSIONS
  The regulating kidney and smoothing liver needling method is an effective method for treatment of hyperplasia of mammary glands and it has regulative action on endocrine and immune functions in the patient with hyperplasia of mammary glands.
authors.affiliation: The First Hospital affiliated to Tianjin University of TCM, Tianjin 300193, China. zhanglifen1708@sina.com
authors.forename: Li-Jen
authors.initials: LJ
authors.lastname: Zhang
authors.forename: A-Feng
authors.initials: AF
authors.lastname: Song
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Lu
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods*; D000328:Adult; D004702:Endocrine Glands / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007668:Kidney / Q000503:physiopathology; D008099:Liver / Q000503:physiopathology; D042361:Mammary Glands, Human / Q000473:pathology*; D008516:Medicine, Chinese Traditional; D013601:T-Lymphocytes / Q000276:immunology*