title: Properties of novel hydroxypropyl methylcellulose films containing chitosan nanoparticles.
abstract: In this study, chitosan nanoparticles were prepared and incorporated in hydroxypropyl methylcellulose (HPMC) films under different conditions. Mechanical properties, water vapor and oxygen permeability, water solubility, and scanning and transmission electron microscopy (SEM and TEM) results were analyzed. Incorporation of chitosan nanoparticles in the films improved their mechanical properties significantly, while also improving film barrier properties significantly. The chitosan poly(methacrylic acid) (CS-PMAA) nanoparticles tend to occupy the empty spaces in the pores of the HPMC matrix, inducing the collapse of the pores and thereby improving film tensile and barrier properties. This study is the first to investigate the use of nanoparticles for the purpose of strengthening HPMC films.
authors.affiliation: Chemistry Dept of UFSCar, São Carlos, SP, Brazil.
authors.forename: M R
authors.initials: MR
authors.lastname: de Moura
authors.forename: R J
authors.initials: RJ
authors.lastname: Avena-Bustillos
authors.forename: T H
authors.initials: TH
authors.lastname: McHugh
authors.forename: J M
authors.initials: JM
authors.lastname: Krochta
authors.forename: L H C
authors.initials: LH
authors.lastname: Mattoso
mesh_terms: D048271:Chitosan / Q000737:chemistry*; D018857:Food Packaging; D065347:Hypromellose Derivatives; D008747:Methylcellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry*; D010100:Oxygen / Q000032:analysis; D010316:Particle Size; D010539:Permeability; D011109:Polymethacrylic Acids / Q000737:chemistry; D012995:Solubility; D013718:Tensile Strength; D014867:Water / Q000032:analysis
chemical_list: D011109:Polymethacrylic Acids; D014867:Water; D065347:Hypromellose Derivatives; D008747:Methylcellulose; D048271:Chitosan; D010100:Oxygen