A single sensory neuron directs both attractive and repulsive odor preferences.
Animal behaviors are subjected to innate preferences, which are usually encoded by dedicated sensory neurons. In this issue of Neuron, Tsunozaki and colleagues show that one olfactory neuron in Caenorhabditis elegans produces two opposing preferences to an odor by regulating cGMP and PKC signaling.
Mori
Ikue
I
Group of Molecular Neurobiology, Division of Biological Science, Graduate School of Science, Nagoya University and CREST-JST, Nagoya, 464-8602, Japan. m46920a@nucc.cc.nagoya-u.ac.jp
D000818:Animals; D001070:Appetitive Behavior / Q000502:physiology; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal / Q000502:physiology*; D017173:Caenorhabditis elegans / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism; D002633:Chemotaxis / Q000235:genetics / Q000502:physiology; D006162:Guanylate Cyclase / Q000235:genetics / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000235:genetics; D009475:Neurons, Afferent / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D012903:Smell / Q000502:physiology*
D029742:Caenorhabditis elegans Proteins; D009419:Nerve Tissue Proteins; C532433:NSY-1 protein, C elegans; D017346:Protein Serine-Threonine Kinases; D006162:Guanylate Cyclase