A clinical review of outcomes of the multimodal treatment study of children with attention-deficit/hyperactivity disorder (MTA).
Over the past decade, the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder has provided a bewildering wealth of data (more than 70 peer-reviewed articles) addressing treatment-related questions for children with attention-deficit/hyperactivity disorder. However, the take-home messages for clinicians may not always be clear. Therefore, this article reviews key findings, including relative benefits of medication and behavioral treatments, long-term effects at 2 and 3 years, treatment mediators and moderators, preliminary delinquency and substance use outcomes, and growth suppression related to stimulant use. Appropriate interpretations of the findings and their limitations are discussed, and recommendations for clinical practice are derived.
Murray
Desiree W
DW
Duke University Medical Center, 718 Rutherford Street, Durham, NC 27705, USA. dwmurray@duke.edu
Arnold
L Eugene
LE
Swanson
Jim
J
Wells
Karen
K
Burns
Karen
K
Jensen
Peter
P
Hechtman
Lily
L
Paykina
Natalya
N
Legato
Lauren
L
Strauss
Tara
T
D000124:Achievement; D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000453:epidemiology / Q000534:rehabilitation*; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000453:epidemiology / Q000534:rehabilitation; D001521:Behavior Therapy; D000697:Central Nervous System Stimulants / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003156:Community Mental Health Services; D015897:Comorbidity; D005500:Follow-Up Studies; D006801:Humans; D007604:Juvenile Delinquency / Q000534:rehabilitation / Q000706:statistics & numerical data; D012917:Social Adjustment; D012951:Socialization; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000534:rehabilitation; D016896:Treatment Outcome
D000697:Central Nervous System Stimulants