title: Towards quantitatively reproducible substrates for SERS.
abstract: There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate analysis of variance (MANOVA), an objective assessment of colloidal SERS reproducibility can be made. This is demonstrated with the analyte cresyl violet, but could be extended to any analyte of interest for which reproducible SERS data are needed.
authors.affiliation: School of Chemistry, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UKM1 7DN. roger.jarvis@manchester.ac.uk
authors.forename: Roger M
authors.initials: RM
authors.lastname: Jarvis
authors.forename: Helen E
authors.initials: HE
authors.lastname: Johnson
authors.forename: Emma
authors.initials: E
authors.lastname: Olembe
authors.forename: Arunkumar
authors.initials: A
authors.lastname: Panneerselvam
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Malik
authors.forename: Mohammad
authors.initials: M
authors.lastname: Afzaal
authors.forename: Paul
authors.initials: P
authors.lastname: O'Brien
authors.forename: Royston
authors.initials: R
authors.lastname: Goodacre
mesh_terms: D000042:Absorption; D048588:Benzoxazines; D003102:Colloids; D003627:Data Interpretation, Statistical; D004492:Edetic Acid; D006046:Gold; D053768:Metal Nanoparticles; D010078:Oxazines; D012834:Silver; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D048588:Benzoxazines; D003102:Colloids; D010078:Oxazines; C028911:cresyl violet; D012834:Silver; D006046:Gold; D004492:Edetic Acid