Zolpidem-induced amnesia and somnambulism: rare occurrences?
Zolpidem, a non-benzodiazepine hypnotic of the imidazopyridine class, is very effective in treating insomnia with previous claims of little adverse effects. However, zolpidem-induced somnambulism and amnesic sleep-related behavioral problems were begun to be reported in literature but no systemic investigation has been undertaken in non-Western cultures. In our current retrospective survey, 5.1% (13 out of 255) of Taiwanese patients reported change in sleep-related behavior as adverse effects. This serves as a reminder for clinicians to inquire regarding any unusual behavior of parasomniac activities when prescribing zolpidem.
Tsai
Jui-Hsiu
JH
Department of Psychiatry, Kaohsiung Municipal Hsiao-Kang Hospital, Taiwan, ROC.
Yang
Pinchen
P
Chen
Cheng-Chung
CC
Chung
Weilum
W
Tang
Tze-Chun
TC
Wang
Shing-Yaw
SY
Liu
Jong-Kang
JK
D000328:Adult; D000647:Amnesia / Q000139:chemically induced* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011725:Pyridines / Q000009:adverse effects*; D012189:Retrospective Studies; D013009:Somnambulism / Q000139:chemically induced* / Q000453:epidemiology / Q000523:psychology*; D013624:Taiwan / Q000453:epidemiology; D000077334:Zolpidem
D006993:Hypnotics and Sedatives; D011725:Pyridines; D000077334:Zolpidem