title: Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.
abstract: Combinatorial solid-phase synthesis of bis-heterocyclic compounds, characterized by the presence of two heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion.
authors.affiliation: Department of Chemistry and Biochemistry, 251 Nieuwland Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Soural
authors.forename: Isabelle
authors.initials: I
authors.lastname: Bouillon
authors.forename: Viktor
authors.initials: V
authors.lastname: Krchnák
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D003432:Cross-Linking Reagents; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D054852:Small Molecule Libraries / Q000138:chemical synthesis*
chemical_list: D003432:Cross-Linking Reagents; D006571:Heterocyclic Compounds; D054852:Small Molecule Libraries