title: On the measurement of the functional properties of the CFTR.
abstract: A number of methods are currently employed to assess the functional properties of CFTR channels and their response to pharmacological potentiators, correction of the defective CFTR trafficking, and vectorial introduction of new proteins. Here we review the most common methods used to assess CFTR channel function. The suitability of each technique to various experimental conditions is discussed.
authors.affiliation: Istituto di Biofisica, CNR, 16149 Genova, Italy. moran@ge.ibf.cnr.it
authors.forename: Oscar
authors.initials: O
authors.lastname: Moran
authors.forename: Olga
authors.initials: O
authors.lastname: Zegarra-Moran
mesh_terms: D003550:Cystic Fibrosis / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000502:physiology*; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology; D021381:Protein Transport / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology
chemical_list: C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator