[Tissue factor molecules and some other indices of coagulation hemostasis in patients with rheumatic heart disease].
This comparative study of interleukins, tissue factor activity, and certain parameters of coagulation hemostasis included patients with rheumatic heart disease. It revealed an increased production of proinflammatory cytokines including interleukin-1b (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in all groups of patients. The procoagulative activity was also enhanced and positively correlated with the IL-1 beta level. Tissue factor activity was directly proportional to the concentration of IL-1 beta and inversely proportional to that of interleukin-4 (IL-4).
Gorbunov
V V
VV
Tsarenok
S Iu
SIu
Rosin
I V
IV
D000328:Adult; D001779:Blood Coagulation Factors / Q000502:physiology*; D005260:Female; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D053583:Interleukin-1beta / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
D001779:Blood Coagulation Factors; D053583:Interleukin-1beta; D014409:Tumor Necrosis Factor-alpha