title: A study of clinico-haematological profiles of pancytopenia in children.
abstract: We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin <10 g/dL, absolute neutrophil count 1.5 x 10(9)/L and platelet count <100 x 10(9)/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5-18 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%.
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India. vineetaguptabhu@gmail.com
authors.forename: V
authors.initials: V
authors.lastname: Gupta
authors.forename: S
authors.initials: S
authors.lastname: Tripathi
authors.forename: V
authors.initials: V
authors.lastname: Tilak
authors.forename: B D
authors.initials: BD
authors.lastname: Bhatia
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000150:complications; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000150:complications; D007938:Leukemia / Q000150:complications; D008297:Male; D010198:Pancytopenia / Q000097:blood / Q000209:etiology*