title: A systematic review of the efficacy of non-pharmacological treatments for depression on glycaemic control in type 2 diabetics.
abstract: OBJECTIVE
  This paper reported a systematic review of three randomised controlled clinical trials evaluating the efficacy of non-pharmacological treatment of depression on glycaemic control in individuals with type 2 diabetes.
  
  
  BACKGROUND
  Depression is associated with poor adherence to self-care regimen in individuals with diabetes. A significant relationship between depression and poor glycaemic control has also been suggested. Hence, the management of depression becomes an important aspect of diabetes care.
  
  
  METHODS
  Systematic review.
  
  
  METHODS
  Cochrane library, Pubmed, MEDLINE, EBM review, ProQuest Medical Bundle and SCOPUS databases were searched using the following medical subject headings or key words - depression, mood disorder, depressive symptoms, diabetes mellitus, glycaemic control, glycated haemoglobin, glucose, psychological therapy, psychotherapy, non-pharmacological therapy and cognitive behaviour therapy. The publication date was limited from 1996-2007. Studies were selected if they used a randomised controlled trial design, were written in English, used non-pharmacological treatments for treating depression, included individuals with type 2 diabetes mellitus as participants and included depressive symptoms and glycaemic control (determined by haemoglobin A(1)C) as outcomes.
  
  
  RESULTS
  Non-pharmacological treatments of depression reduce depressive symptoms in diabetic patients. However, cognitive behaviour therapy did not improve glycaemic control. The treatment effect sizes for glycaemic control in the two collaborative-care programmes were also small.
  
  
  CONCLUSIONS
  The available evidence indicated that non-pharmacological treatment of depression had limited effect on glycaemic control in individuals with type 2 diabetes.
  
  
  CONCLUSIONS
  The depression-focused interventions might not achieve optimal diabetes-related outcomes. The beneficial effect of psychological treatment for glycaemic control may be strengthened by employing treatments tailored to each individual's diabetes self-care needs in addition to depression management.
authors.affiliation: Graduate Institute of Medical Science, College of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Mei-Yeh
authors.initials: MY
authors.lastname: Wang
authors.forename: Pei-Shan
authors.initials: PS
authors.lastname: Tsai
authors.forename: Kuei-Ru
authors.initials: KR
authors.lastname: Chou
authors.forename: Ching-Min
authors.initials: CM
authors.lastname: Chen
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003863:Depression / Q000150:complications / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications*; D006801:Humans; D010349:Patient Compliance; D016032:Randomized Controlled Trials as Topic
chemical_list: D001786:Blood Glucose