Insight into the antibacterial drug design and architectural mechanism of peptide recognition from the E. faecium peptide deformylase structure.
Nam
Ki Hyun
KH
Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea.
Ham
Jung Il
JI
Priyadarshi
Amit
A
Kim
Eunice Eunkyeong
EE
Chung
NamHyun
N
Hwang
Kwang Yeon
KY
D000581:Amidohydrolases / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism; D018360:Crystallography, X-Ray; D015195:Drug Design; D016984:Enterococcus faecium / Q000201:enzymology*; D008314:Malonates / Q000737:chemistry* / Q000378:metabolism; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D008314:Malonates; D010455:Peptides; C030290:malonic acid; D000581:Amidohydrolases; C084507:peptide deformylase