title: Comparative evaluation of two simple diffuse reflectance models for biological tissue applications.
abstract: We present a comparative evaluation of two simple diffuse reflectance models for biological tissue applications. One model is based on a widely accepted and used in biomedical optics implementation of diffusion theory, and the other one is based on a semiempirical approach derived from basic physical principles. We test the models on tissue phantoms and on human skin, utilizing a standard six-around-one optical fiber probe for light delivery and collection. We show that both models are suitable for use with an optical fiber probe and illustrate the potential, applicability, and validity range of the models.
authors.affiliation: Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece. gzonios@alum.mit.edu
authors.forename: George
authors.initials: G
authors.lastname: Zonios
authors.forename: Ioannis
authors.initials: I
authors.lastname: Bassukas
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Dimou
mesh_terms: D003198:Computer Simulation; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008027:Light; D008954:Models, Biological; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D012031:Refractometry / Q000379:methods*; D012542:Scattering, Radiation; D013057:Spectrum Analysis / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*