title: [Multiple brain abscesses of odontogenic origin caused by Fusobacterium nucleatum].
abstract: Infection caused by the anaerobic gram-negative rod Fusobacterium nucleatum belongs to endogenous infections. A 41-year-old man developed multiple brain abscesses of odontogenic origin. The main causes were poor oral hygiene and no dental check-ups. Pus aspired from a site in the brain contained DNA of the bacterium Fusobacterium nucleatum. Several teeth with periapical abscesses were extracted. Initially, the patient was treated empirically with a combination of cefotaxime and metronidazole (18 days). Subsequently, co-trimoxazole and rifampicin were administered (8 months). Four and eight months after the onset of the disease, MRI scans revealed only persistent residual changes in the brain parenchyma; the patient was asymptomatic, with no neurological signs and back at work.
authors.affiliation: Klinika infekcních chorob Lékarské fakulty Masarykovy univerzity a Fakultní nemocnice Brno. lstefanikova@fnbrno.cz
authors.forename: L
authors.initials: L
authors.lastname: Stefániková
authors.forename: M
authors.initials: M
authors.lastname: Freibergerová
authors.forename: P
authors.initials: P
authors.lastname: Husa
authors.forename: M
authors.initials: M
authors.lastname: Kerkovský
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*; D005491:Focal Infection, Dental / Q000150:complications* / Q000382:microbiology; D005674:Fusobacterium Infections / Q000175:diagnosis* / Q000209:etiology; D016967:Fusobacterium nucleatum; D006801:Humans; D008297:Male