title: The dynamic transfer of 3H and 14C in mammals: a proposed generic model.
abstract: Associated with the present debate regarding the potential revival of nuclear energy there is an increased interest in assessing the radiological risk to the public and also the environment. Tritium and (14)C are key radionuclides of interest in many circumstances (e.g. heavy water reactors, waste storage and fusion reactors). Because the stable analogues of these two radionuclides are integral to most biological compounds, their modelling should follow general principles from life sciences. In this paper, a model of the dynamics of (14)C and (3)H in mammals is proposed on the basis of metabolic understanding and of, as far as possible, readily available data (e.g. for organ composition and metabolism). The model is described together with validation tests (without calibration) for a range of farm animals. Despite simplifications, the model tests are encouraging for a range of animal types and products (tissues and milk), and further improvements are suggested.
authors.affiliation: Life and Environmental Physics Department, Horia Hulubei National Institute for Physics and Nuclear Engineering, 407 Atomistilor St., POB MG-6, 077125, Bucharest-Magurele, Romania. galdan@ifin.nipne.ro
authors.forename: D
authors.initials: D
authors.lastname: Galeriu
authors.forename: A
authors.initials: A
authors.lastname: Melintescu
authors.forename: N A
authors.initials: NA
authors.lastname: Beresford
authors.forename: H
authors.initials: H
authors.lastname: Takeda
authors.forename: N M J
authors.initials: NM
authors.lastname: Crout
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000033:anatomy & histology / Q000378:metabolism; D002250:Carbon Radioisotopes / Q000378:metabolism; D003612:Dairying; D004784:Environmental Monitoring / Q000379:methods*; D008460:Meat; D008892:Milk / Q000378:metabolism; D008954:Models, Biological; D014316:Tritium / Q000378:metabolism*; D014781:Viscera / Q000378:metabolism
chemical_list: D002250:Carbon Radioisotopes; D014316:Tritium