Effectiveness of LigaSure diathermy coagulation in liver surgery.
The principal cause of perioperative morbidity and mortality following hepatic resection is excessive intraoperative hemorrhage. This study evaluates the operative use of the LigaSure device in sealing ductal structures during major and minor hepatic resections. Patients were analyzed between June 1994 and December 2005, comparing 89 randomly selected cases undergoing hepatic resections using the clamp-crushing technique with LigaSure electrocautery and hepatic inflow occlusion where appropriate with 70 patients undergoing various hepatic resections using the clamp-crushing technique alone with hepatic inflow occlusion where appropriate. Intraoperative blood loss and perioperative blood transfusion requirements were significantly less for patients in the LigaSure group. LigaSure-assisted hepatic resection was generally performed more quickly than the conventional clamp-crushing technique. The overall maximum postoperative AST, ALT, and bilirubin serum levels were similar in the two groups, as was the incidence of major postoperative complications. The LigaSure device in this randomized study is safe and simple to use, resulting in less perioperative blood loss and transfusion requirement during hepatic parenchymal transection.
Chiappa
Antonio
A
Department of General Surgery, European Institute of Oncology, University of Milan, Milan, Italy.
Bertani
Emilio
E
Biffi
Roberto
R
Zbar
Andrew P
AP
Viale
Giuseppe
G
Pruneri
Giancarlo
G
Bellomi
Massimo
M
Venturino
Marco
M
Andreoni
Bruno
B
D000368:Aged; D004564:Electrocoagulation / Q000295:instrumentation* / Q000401:mortality* / Q000706:statistics & numerical data; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006498:Hepatectomy / Q000295:instrumentation* / Q000401:mortality* / Q000706:statistics & numerical data; D006801:Humans; D007558:Italy; D008113:Liver Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery*; D008297:Male; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D016896:Treatment Outcome