title: The effect on the recovery profile of a change from enflurane to desflurane during the latter part of anaesthesia.
abstract: This study compared emergence and recovery characteristics after either enflurane anaesthesia or crossover from enflurane to desflurane anaesthesia. At an estimated 1 h prior to the end of operation, enflurane was either reduced (group E, n = 23) or replaced with desflurane (group X, n = 23). At the end of the operation, emergence and recovery characteristics of the two groups were compared. The crossover technique accelerated recovery compared with enflurane anaesthesia. The time taken for the eyes to open in response to painful pinching or a verbal command, and to regain awareness of age and name, were significantly shorter after crossover anaesthesia than after enflurane anaesthesia. The digit symbol substitution test and serial seven test scores were significantly better in patients subjected to crossover anaesthesia than in those subjected to enflurane anaesthesia. We conclude that, during surgery, the substitution of enflurane with desflurane in the latter part of anaesthesia can improve recovery.
authors.affiliation: Department of Anaesthesiology and Pain Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
authors.forename: H
authors.initials: H
authors.lastname: Kang
authors.forename: S-G
authors.initials: SG
authors.lastname: Park
authors.forename: C-W
authors.initials: CW
authors.lastname: Baek
authors.forename: J-W
authors.initials: JW
authors.lastname: Park
authors.forename: Y-H
authors.initials: YH
authors.lastname: Jung
authors.forename: Y-C
authors.initials: YC
authors.lastname: Woo
authors.forename: J-Y
authors.initials: JY
authors.lastname: Kim
authors.forename: G-H
authors.initials: GH
authors.lastname: Koo
mesh_terms: D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D018685:Anesthetics, Inhalation / Q000378:metabolism* / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D000077335:Desflurane; D004737:Enflurane / Q000378:metabolism* / Q000494:pharmacology; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D013990:Tidal Volume / Q000187:drug effects
chemical_list: D018685:Anesthetics, Inhalation; D004737:Enflurane; D000077335:Desflurane; D007530:Isoflurane