Temporary portocaval shunt in orthotopic liver transplantation: need for a standardized approach?
Maintenance of portal and systemic venous return during the anhepatic phase of liver transplantation (LT) improves hemodynamic stability. With the piggyback technique, caval return is maintained; however, temporary clamping of the portal vein is still necessary. The use of a temporary portocaval shunt (TPCS) has been proposed to minimize the effect of portal venous interruption. The aim of this study was to perform a systematic review of the literature to determine whether there is evidence to support the routine use of a TPCS in LT. An electronic search of the literature from 1963 to 2007 was performed. A total of 4386 articles were identified, of which 8 met all the criteria and were included in the study. Because of the variability in reporting and the small number of studies, statistical comparison was not possible; however, a trend toward a shorter operative time, less blood product transfusion, and maintenance of higher mean arterial pressures during portal vein clamping was seen in patients with a TPCS. In conclusion, the available evidence, albeit scarce, supports the use of a TPCS in patients undergoing LT. A prospective randomized study of patients most likely to benefit from a TPCS is necessary to substantiate these findings.
Davila
Diego
D
King's College London School of Medicine at Denmark Hill, Institute of Liver Studies, King's College Hospital, Denmark Hill, Camberwell, London, United Kingdom.
Bartlett
Adam
A
Heaton
Nigel
N
D006801:Humans; D016031:Liver Transplantation / Q000592:standards*; D011167:Portacaval Shunt, Surgical