title: Phase-contrast MR imaging support for the diagnosis of aqueductal stenosis.
abstract: OBJECTIVE
  Patients with aqueductal stenosis (AS) present with various clinical and radiologic features. Conventional MR imaging provides useful information in AS but depends on a subjective evaluation by the neuroradiologist. The purpose of this study was to evaluate the support of the phase-contrast MR imaging (PC-MR imaging) technique (sensitive to CSF flows) for the diagnosis of AS.
  
  
  METHODS
  We retrospectively considered 17 patients who underwent PC-MR imaging to explore hydrocephalus, with the absence of CSF flow at the aqueductal level. We analyzed their clinical and morphologic MR imaging data.
  
  
  RESULTS
  None of the usually reported direct or indirect signs of aqueductal obstruction were seen in 7 patients in whom the clinical suggestion of AS was confirmed by PC-MR imaging results. Seven patients in this population had a third ventriculostomy, and 5 of them were among those in whom conventional MR imaging failed to reveal signs of aqueductal obstruction. All of these 7 patients had a positive postsurgical outcomes. The analysis of CSF and vascular dynamic data in this population was compared with an aged-matched population, and these data were found similar except for the fourth ventricular CSF flush flow latency.
  
  
  CONCLUSIONS
  PC-MR imaging supports the diagnosis of CSF flow blockage at the aqueductal level in a reliable, reproducible, and rapid way, which aids in the diagnosis of AS in patients with clinical and/or radiologic suggestion of obstructive hydrocephalus. We, therefore, suggest using this technique in the current evaluation of hydrocephalus.
authors.affiliation: Department of Neurology, Amiens University Hospital, Amiens Cedex, France. stoquart-elsankari.soraya@chu-amiens.fr
authors.forename: S
authors.initials: S
authors.lastname: Stoquart-El Sankari
authors.forename: P
authors.initials: P
authors.lastname: Lehmann
authors.forename: C
authors.initials: C
authors.lastname: Gondry-Jouet
authors.forename: A
authors.initials: A
authors.lastname: Fichten
authors.forename: O
authors.initials: O
authors.lastname: Godefroy
authors.forename: M-E
authors.initials: ME
authors.lastname: Meyer
authors.forename: O
authors.initials: O
authors.lastname: Baledent
mesh_terms: D000328:Adult; D002535:Cerebral Aqueduct / Q000473:pathology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology*; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity