Surgical outcomes and survival after multiorgan resection for locally advanced gastric cancer.
BACKGROUND
Multiple organ resection for locally advanced (assumed T4) gastric cancer is associated with high morbidity and mortality. Our aim was to evaluate the efficacy of these surgeries with regard to surgical morbidity, mortality, and survival.


METHODS
Fifty-six patients underwent potentially radical gastrectomy combined with invaded organ resection. Early and late results of multiorgan resection and clinicopathologic factors influencing these results were evaluated.


RESULTS
Forty patients (71.4%) received 1 additional organ resection and 16 patients (28.6%) received 2 or more additional organ resections. Postoperative morbidity and mortality was 37.5% and 12.5%, respectively. Resection of 2 or more additional organs increased postoperative morbidity and advanced age increased mortality. The 1- and 3-year survival rates were 53.3% and 28.1%, respectively. Advanced age, lymph node metastasis, and resection of more than 1 additional organ were significant prognostic factors for survival.


CONCLUSIONS
For patients with locally advanced gastric carcinoma, multiple organ resection is worthwhile with careful patient selection.
Ozer
Ilter
I
Turkiye Yuksek Ihtisas Training and Research Hospital, Mamak, Ankara, Turkey. ilterozer@yahoo.com
Bostanci
E Birol
EB
Orug
Taner
T
Ozogul
Yusuf B
YB
Ulas
Murat
M
Ercan
Metin
M
Kece
Can
C
Atalay
Fuat
F
Akoglu
Musa
M
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013156:Splenectomy / Q000379:methods*; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D016896:Treatment Outcome