Chemical constituents from the flower of Datura metel L.
Phytochemical investigation of the 50% ethanol eluate fraction of macroporous resin for the flower of Datura metel L. led to the isolation of a new compound named yangjinhualine A (1) and five known megastigmane sesquiterpenes through repeated silica gel and ODS column chromatography and semipreparative HPLC. The structures of these compounds were determined by spectroscopic methods, including 2D-NMR, ESI-MS, and HR-ESI-MS spectrometry as well as by comparison with published data. Five known megastigmane sesquiterpenes were also isolated from D. metel L. for the first time.
Kuang
Hai-xue
HX
Heilongjiang University of Chinese Medicine, Harbin, 150040, People's Republic of China. hxkuang@hotmail.com
Yang
Bing-you
BY
Xia
Yong-gang
YG
Feng
Wei-sheng
WS
D032302:Datura / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D010936:Plant Extracts