title: Velocity tracking, a new and user independent method for detecting regional function of the left ventricle.
abstract: BACKGROUND
  The use of two-dimensional echocardiography (2D echo) for detection of ischaemia is limited due to high user dependency. Longitudinal motion is sensitive for ischaemia and usable for quantitative measurement of longitudinal myocardial function but time consuming. Velocity tracking (VeT) is a new method that gives an easy three-dimensional understanding of both systolic and diastolic regional motion, using colour coded bull's eye presentation of longitudinal velocity, derived from colour coded tissue Doppler. The aim of this study was to test the accuracy of VeT in detecting ischaemia in non-ST-segment elevation myocardial infarction (NSTEMI) patients bedside.
  
  
  METHODS
  Twenty patients with NSTEMI and 10 controls were included. Echocardiography was performed within 24 h of symptoms and prior to coronary angiography. Bull's eye plots presenting the peak systolic velocity (PSV) and the sum of PSV and the E-wave-velocity (PSV+E) were created using our developed software. VeT was compared to expert wall motion scoring (WMS) and bedside echo. We used the clinical conclusion based on ECG, angiography and clinical picture as 'gold standard'.
  
  
  RESULTS
  Sensitivity for ischaemia with VeT (PSV+E) was 85% and specificity 60%. The corresponding sensitivities for expert WMS were 75% (specificity 40%). For regional analysis VeT and WMS showed comparable results with correct regional outcome in 11/20 of patients both superior to bedside echo.
  
  
  CONCLUSIONS
  Velocity tracking is a promising technique that provides an easily understandable three-dimensional bull's eye plot for assessment of regional left ventricular longitudinal velocity with great potential for detection of regional dysfunction and myocardial ischaemia.
authors.affiliation: Department of Cardiology, Karolinska University Hospital Huddinge, Stockholm, Sweden. carl.westholm@karolinska.se
authors.forename: Carl
authors.initials: C
authors.lastname: Westholm
authors.forename: Anna
authors.initials: A
authors.lastname: Bjällmark
authors.forename: Matilda
authors.initials: M
authors.lastname: Larsson
authors.forename: Per
authors.initials: P
authors.lastname: Jacobsen
authors.forename: Lars-Ake
authors.initials: LA
authors.lastname: Brodin
authors.forename: Reidar
authors.initials: R
authors.lastname: Winter
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003196:Computer Graphics; D017023:Coronary Angiography; D018618:Echocardiography, Doppler, Color; D004562:Electrocardiography; D005240:Feasibility Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D010865:Pilot Projects; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013997:Time Factors; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology