[Streptococcus pneumoniae endocarditis diagnosed with polymerase chain reaction].
A 60-year old man was admitted with sepsis and meningitis of unknown aetiology. Underlying aortic valve endocarditis was diagnosed by echocardiography and severe insufficiency led to aortic valve replacement. Application of broad-range PCR to cusp tissue revealed a DNA product, and a diagnosis of Streptococcus pneumoniae endocarditis was obtained by DNA sequencing.
Rasmussen
Rasmus Vedby
RV
Kardiologisk Afdeling P, Gentofte Hospital, DK-2900 Hellerup. nibru@geh.regionh.dk.
Kemp
Michael
M
Bangsborg
Jette M
JM
Kjerulf
Anne Vinther
AV
Christensen
John Brochorst
JB
Bruun
Niels Eske
NE
D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D013296:Streptococcus pneumoniae / Q000235:genetics / Q000302:isolation & purification; D014463:Ultrasonography