title: Normal values of echocardiographic parameters in relation to age in a healthy Japanese population: the JAMP study.
abstract: BACKGROUND
  Normal values for echocardiographic measurements and the relationship between these parameters and age in a large Japanese population are still unknown.
  
  
  RESULTS
  A total of 700 healthy Japanese aged 20-79 years underwent 2-dimensional and Doppler echocardiography at collaborating institutions. The respective mean values obtained in men and women were as follows: septal wall thickness, 0.9+/-0.1 and 0.8+/-0.1 cm; posterior wall thickness, 0.9+/-0.1 and 0.8+/-0.1 cm; left ventricular (LV) diastolic diameter, 4.8+/-0.4 and 4.4+/-0.3 cm; LV systolic diameter, 3.0+/-0.4 and 2.8+/-0.3 cm; LV diastolic volume, 93+/-20 and 74+/-17 ml; LV systolic volume, 33+/-20 and 25+/-7 ml; LV ejection fraction, 64+/-5 and 66+/-5%; maximum left atrial (LA) volume, 42+/-14 and 38+/-12 ml. Aortic root diameter, LV wall thickness, and LV mass slightly increased with age, whereas indexed LA volume did not vary with age. Diastolic parameters assessed by mitral inflow and mitral annular velocities declined with age, as previously reported.
  
  
  CONCLUSIONS
  Normal values of echocardiographic measurements in a large Japanese population are reported for the first time; several systolic and diastolic parameters varied with age. These results provide important reference values that should be useful in routine clinical practice as well as in clinical trials.
authors.affiliation: Juntendo University, Tokyo, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Daimon
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Yukio
authors.initials: Y
authors.lastname: Abe
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hirata
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hozumi
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Ishii
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ito
authors.forename: Katsuomi
authors.initials: K
authors.lastname: Iwakura
authors.forename: Chisato
authors.initials: C
authors.lastname: Izumi
authors.forename: Masunori
authors.initials: M
authors.lastname: Matsuzaki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Minagoe
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Abe
authors.forename: Kazuya
authors.initials: K
authors.lastname: Murata
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakatani
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Negishi
authors.forename: Ken
authors.initials: K
authors.lastname: Yoshida
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Tanabe
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kotaro
authors.initials: K
authors.lastname: Tokai
authors.forename: Junichi
authors.initials: J
authors.lastname: Yoshikawa
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D044466:Asian People; D001783:Blood Flow Velocity / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000502:physiology*; D016276:Ventricular Function / Q000502:physiology*