Conventional and advanced implant treatment in the type II diabetic patient: surgical protocol and long-term clinical results.
OBJECTIVE
To investigate the effect of type-2 diabetes on implant survival and complication rate.


METHODS
Prospective study enrolling type-2 diabetic patients suffering from edentulism, having a mean perioperative HbA1c level of 7.2%, and compliant with a maintenance program. All the patients underwent dental and periodontal examinations and had laboratory testing for HbA1c, fasting plasma glucose, blood lipids, and microalbuminuria. Nondiabetic patients matched for implant treatment indication served as controls. The influence of clinical diabetes-related factors and periodontal parameters (Plaque Index, bleeding on probing, probing depth) on implant survival were assessed via univariate then multivariate methods.


RESULTS
Forty-five diabetic patients, followed for 1 to 12 years, mean age 64.7 years, received 255 implants: 143 following a classical protocol and 112 in cases of sinus floor elevation, immediate loading, and guided bone regeneration. Forty-five nondiabetic control patients received 244 implants: 142 following a classical protocol and 102 in cases of advanced surgery. Implant survival following conventional or advanced implant therapy was not statistically different between the well-controlled (HbA1c < 7%, P = .33) and the fairly well-controlled group (HbA1c 7% to 9%, P = .37). The overall survival rate for the diabetic group was 97.2% (control 98.8%) and was not significantly different for age, gender, diabetes duration, smoking, or type of hypoglycemic therapy. The mean peri-implant bone loss was 0.41 +/- 0.58 mm (control, 0.49 +/- 0.64 mm). PI and BOP fairly correlated with postoperative complications. HbA1c was the only multivariate independent factor affecting the complication rate (P = .04). No statistically significant difference was found for patients (P = .81) or for implants (P = .66) for the advanced surgery cases or the conventional approach in diabetic patients compared to nondiabetic patients.
Tawil
Georges
G
Department of Periodontology, St Joseph University, Beirut, Lebanon. gtawil@inco.com.lb
Younan
Roland
R
Azar
Pierre
P
Sleilati
Ghassan
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000209:etiology*; D016022:Case-Control Studies; D003758:Dental Implantation, Endosseous / Q000009:adverse effects / Q000379:methods*; D019232:Dental Restoration Failure; D003922:Diabetes Mellitus, Type 1 / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013516:Oral Surgical Procedures, Preprosthetic; D010512:Periodontal Index; D010518:Periodontitis / Q000209:etiology; D011446:Prospective Studies; D011859:Radiography; D012907:Smoking; D016896:Treatment Outcome
D006442:Glycated Hemoglobin