title: Prolongation of hospital stay and additional costs due to nosocomial bloodstream infection in an Algerian neonatal care unit.
abstract: BACKGROUND
  Previous studies from developed countries reported that nosocomial bloodstream infection (BSI) in neonatal care units (NCUs) increases length of stay and costs. However, no such information is available for Algerian NCUs.
  
  
  OBJECTIVE
  To evaluate the influence of BSI in neonates on additional charges and length of hospital stay.
  
  
  METHODS
  Prospective, nested case-control study.
  
  
  METHODS
  The 47-bed NCU of the University Hospital of Blida, Algeria.
  
  
  METHODS
  A total of 83 neonates with BSIs (case patients) and 166 neonates without BSIs (control patients), admitted to the NCU during the study period (April 2004 through December 2007), were matched for sex, birth weight, length of NCU stay, and year of hospital admission. Each patient's length of stay in the NCU was obtained prospectively on daily rounds. The estimated cost of each NCU-day was provided by the hospital's finance department. The cost of antibiotics prescribed was provided by the hospital's pharmacy department.
  
  
  RESULTS
  The mean additional length of NCU stay for case patients, compared with control patients, was 9.2 days (24.3 vs 15.1 days). The mean additional cost of antibiotics was dollars 546. The mean cumulative additional cost was dollars 1,315.
  
  
  CONCLUSIONS
  This study highlights the effect of BSI on extra costs for NCU patients, especially costs due to prolongation of hospital stay and increased antibiotic use, and suggests that NCUs in Algeria have a financial interest in reducing the rate of BSI.
authors.affiliation: Department of Epidemiology and Preventive Medicine, University Hospital of Blida, Zabana, Blida, Algeria. mlatif@mail.univ-blida.dz
authors.forename: Mohamed Lamine
authors.initials: ML
authors.lastname: Atif
authors.forename: Fetta
authors.initials: F
authors.lastname: Sadaoui
authors.forename: Abdeldjallil
authors.initials: A
authors.lastname: Bezzaoucha
authors.forename: Chawki Ahmed
authors.initials: CA
authors.lastname: Kaddache
authors.forename: Rachida
authors.initials: R
authors.lastname: Boukari
authors.forename: Salima
authors.initials: S
authors.lastname: Djelato
authors.forename: Nora
authors.initials: N
authors.lastname: Boubechou
mesh_terms: D000462:Algeria / Q000453:epidemiology; D000900:Anti-Bacterial Agents / Q000191:economics / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology*; D016022:Case-Control Studies; D003428:Cross Infection / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology*; D005260:Female; D017721:Hospital Costs; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay / Q000191:economics*; D008297:Male; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents