csrA inhibits the formation of biofilms by Vibrio vulnificus.
PCR screening of the shellfish-borne pathogen Vibrio vulnificus revealed csrA-negative strains, and these strains formed increased biofilm compared to csrA-positive strains. Complementation in trans with csrA resulted in reduced biofilm formation, similar to that by csrA(+) strains. Our results provide evidence that csrA inhibits biofilm formation in V. vulnificus.
Jones
Melissa K
MK
Department of Biology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Warner
Elizabeth B
EB
Oliver
James D
JD
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D018441:Biofilms / Q000254:growth & development*; D004269:DNA, Bacterial / Q000235:genetics; D017353:Gene Deletion; D005816:Genetic Complementation Test; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods; D041261:Vibrio vulnificus / Q000235:genetics / Q000502:physiology*
D001426:Bacterial Proteins; D004269:DNA, Bacterial