title: Treatment of peritoneal mesothelioma in pediatric patients.
abstract: Peritoneal mesothelioma is a rare and often aggressive malignancy, mostly affecting asbestos exposed adults. We present four pediatric peritoneal cases treated with a cisplatin-based doublet regimen, the standard of care in the systemic therapy of adult mesothelioma. Treatment was well tolerated, and three of these patients have achieved long-term survival. The fathers of three of the patients worked in the construction industry and may have been the source of indirect asbestos exposure.
authors.affiliation: Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
authors.forename: Leigh-Anne
authors.initials: LA
authors.lastname: Cioffredi
authors.forename: Pasi A
authors.initials: PA
authors.lastname: Jänne
authors.forename: David M
authors.initials: DM
authors.lastname: Jackman
mesh_terms: D000293:Adolescent; D001194:Asbestos; D002945:Cisplatin / Q000627:therapeutic use; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy*; D010534:Peritoneal Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001194:Asbestos; D002945:Cisplatin