Effect of Bacopa monniera (Linn.) on lipid peroxidation and lipofuscinogenesis in prostate gland of D-galactose induced aging mice, Mus musculus.
The levels of malondialdehyde and lipofuscin pigments were increased in the prostate of D-galactose (0.5 ml/day, sc, for 20 days) induced aging mice. After B. monniera (40 mg/kg body weight for 20 days) ethanol leaf extract administration levels of both the parameters were reduced significantly. The results suggest that B. monniera prevents formation of malondialdehyde and lipofuscin pigments which are the indicators of aging.
Kalamade
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Department of Zoology, Shivaji University, Kolhapur 416 004, India. vahidakalamade@yahoo.co.in
Pillai
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Kalamade
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D000375:Aging / Q000502:physiology*; D000818:Animals; D034681:Bacopa / Q000737:chemistry*; D005690:Galactose / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011467:Prostate / Q000187:drug effects* / Q000378:metabolism
D010936:Plant Extracts; D005690:Galactose