Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy.
BACKGROUND
Tumor recurrence following radical cystectomy for a low-grade superficial transitional cell carcinoma (TCC) is exceedingly uncommon and has not been reported previously.


METHODS
We describe a case of a young male presenting with anorexia, weight loss and a large, painful locally destructive pelvic recurrence, ten years after radical cystoprostatectomy. The pathology was consistent with a low-grade urothelial carcinoma. After an unsuccessful treatment with cisplatin-based chemotherapy, the patient underwent a curative intent hemipelvectomy with complete excision of tumor and is disease free at one year follow-up.


CONCLUSIONS
A literature review related to this unusual presentation is reported and a surgical solutions over chemotherapy and radiotherapy is proposed.
Dangle
Pankaj P
PP
The James Cancer Hospital and Solove Research Institute, Ohio State University and Comprehensive Cancer Center, Columbus, Ohio 43210, USA. Pankaj.Dangle@osumc.edu
Wang
Wenle Paul
WP
Mayerson
Joel
J
Mortazavi
Amir
A
Monk
Paul
P
D002291:Carcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000601:surgery; D015653:Cystectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000556:secondary / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery