[Long-term efficacy of endoscopic excision of rectal carcinoids].
OBJECTIVE
To evaluate the long-term efficacy of endoscopic excision for rectal carcinoids.


METHODS
Clinical data of 91 patients with rectal carcinoids treated by endoscopic excision from 2000 to 2007 were analyzed retrospectively.


RESULTS
The average size of the primary tumor was 0.8 cm(range 0.3 to 2.3 cm). All the tumors were localized within the submucosal layer showing typical histology without lymphatic or vessel infiltration. Follow-up was available for 80 patients with mean 32.5 months (range 6 to 96 months). There was no recurrence in 65 patients with tumor size < 1.0 cm. Recurrence occurred in 3 cases among 25 patients with tumor size from 1.0 to 2.0 cm, and 1 died of hepatic metastasis. The 1-, 3-, and 5-year survival rates of the patients were 100%, 98.0%, and 91.4% respectively.


CONCLUSIONS
Tumor size and depth of invasion are two important prognostic factors of rectal carcinoids. Endoscopic excision is useful for rectal carcinoid patients with tumor size < 1.0 cm and located within the submucosal layer.
Zhang
Yi-qun
YQ
Department of Endoscopic Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhou
Ping-hong
PH
Xu
Mei-dong
MD
Zhong
Yun-shi
YS
Chen
Wei-feng
WF
Ma
Li-li
LL
Qin
Wen-zheng
WZ
Cai
Xian-li
XL
Yao
Li-qing
LQ
D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult