[Hypophosphatemic osteomalacia].
Hypophosphatemic osteomalacia first presenting in adulthood is a rare disease. It is characterized by decreased serum phosphate, renal phosphate wasting, elevated alkaline phosphatase, and osteomalacia. The authors present a case with typical constellation of an oncogenic (tumor-induced) osteomalacia, the possible differential diagnosis, diagnostic evaluation, and complete healing after tumor resection. The new concepts of hereditary and acquired hypophosphatemic osteomalacia are discussed helping us understand this rare disease.
Bullmann
Catharina
C
Endokrinologikum, Zentrum für Hormon- und Stoffwechselstörungen, Reproduktionsmedizin und Pränatale Medizin, Lornsenstrasse 4-6, Hamburg, Germany. catharina.bullmann@endokrinologikum.com
Benker
Georg
G
Rosien
Ulrich
U
Delling
Günther
G
Siggelkow
Heide
H
Schulte
Heinrich Maria
HM
D000328:Adult; D001706:Biopsy; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005346:Fibroblast Growth Factors / Q000097:blood; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D017674:Hypophosphatemia / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008684:Metatarsus; D010014:Osteolysis / Q000209:etiology; D010018:Osteomalacia / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D010281:Parathyroid Hormone / Q000097:blood; D011860:Radiography, Abdominal; D012272:Ribs / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D010281:Parathyroid Hormone; D005346:Fibroblast Growth Factors