Dynamic resolution of N-Boc-2-lithiopiperidine.
Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.
Coldham
Iain
I
Department of Chemistry, University of Sheffield, Sheffield, UKS3 7HF. i.coldham@sheffield.ac.uk
Raimbault
Sophie
S
Chovatia
Praful T
PT
Patel
Jignesh J
JJ
Leonori
Daniele
D
Sheikh
Nadeem S
NS
Whittaker
David T E
DT