title: Giant cell reparative granuloma in the mandible--case report and review of the literature.
abstract: OBJECTIVE
  Central giant cell granuloma (GCG) is defined as an intraosseous lesion consisting of cellular fibrous tissue containing multiple foci of hemorrhage, aggregations of multinucleated giant cells. Peripheral GCG is a reactive exophytic lesion occurring on the gingiva and alveolar ridge originating from the periosteum or periodontal membrane, usually as a result of local irritating factors.
  
  
  METHODS
  The case report evaluated long-term therapy of giant cell granuloma. A 9-year-old boy generally healthy was admitted to our clinic with a swelling in the frontal area of mandible. Giant cell granuloma was detected. Surgical curettage was applied. After 3 years of the operation, the recurrence was seen during the physical examination. The new GCG was removed. The prosthetic rehabilitation including implants insertion (18-year-old adult patient) finished treatment.
  
  
  RESULTS
  Three-year recall confirmed the stability of treatment.
  
  
  CONCLUSIONS
  Esthetical and functional therapy is of great importance in the patient's rehabilitation.
authors.affiliation: Charles University in Prague, 2nd Medical School, Department of Paediatric Stomatology, Prague, Czech Republic.
authors.forename: M
authors.initials: M
authors.lastname: Hubácek
authors.forename: T
authors.initials: T
authors.lastname: Dostálová
authors.forename: M
authors.initials: M
authors.lastname: Bartonová
authors.forename: J
authors.initials: J
authors.lastname: Kozák
authors.forename: M
authors.initials: M
authors.lastname: Seydlová
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000601:surgery; D019647:Oral Surgical Procedures / Q000379:methods