Chitosan/polyethylene glycol diacrylate films as potential wound dressing material.
Michael addition reaction of Chitosan (CS) and polyethylene glycol diacrylate (PEGDA) was carried out successfully in acidic solution. Films with CS/PEGDA weight ratios from 100/0 to 0/100 in 10% increments were analyzed by Fourier transform infrared (FTIR) spectroscopy, Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD). Additionally, the films were characterized by measuring mechanical property, swelling property. The potential application of the CS/PEGDA film as wound dressing material was evaluated in vitro by using mouse fibroblasts (L929) as reference cell lines, indirect cytotoxicity assessment indicated that CS/PEGDA films were nontoxic to L929 cell.
Zhang
Xiaodan
X
State Key Laboratory of Chemical Resource Engineering, Key Lab of Beijing City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
Yang
Dongzhi
D
Nie
Jun
J
D000818:Animals; D001458:Bandages; D001672:Biocompatible Materials / Q000737:chemistry; D002448:Cell Adhesion; D045744:Cell Line, Tumor; D048271:Chitosan / Q000737:chemistry; D051379:Mice; D011092:Polyethylene Glycols / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
D001672:Biocompatible Materials; C437167:poly(ethylene glycol)diacrylate; D011092:Polyethylene Glycols; D048271:Chitosan