A novel, cellulose synthesis inhibitory action of ancymidol impairs plant cell expansion.
The co-ordination of cell wall synthesis with plant cell expansion is an important topic of contemporary plant biology research. In studies of cell wall synthesis pathways, cellulose synthesis inhibitors are broadly used. It is demonstrated here that ancymidol, known as a plant growth retardant primarily affecting gibberellin biosynthesis, is also capable of inhibiting cellulose synthesis. Its ability to inhibit cellulose synthesis is not related to its anti-gibberellin action and possesses some unique features never previously observed when conventional cellulose synthesis inhibitors were used. It is suggested that ancymidol targets the cell wall synthesis pathway at a regulatory step where cell wall synthesis and cell expansion are coupled. The elucidation of the ancymidol target in plant cells could potentially contribute to our understanding of cell wall synthesis and cell expansion control.
Hofmannová
Jana
J
Department of Plant Physiology, Faculty of Science, Charles University Prague, Vinicná 5, Prague 128 44, Czech Republic.
Schwarzerová
Katerina
K
Havelková
Lenka
L
Boríková
Petra
P
Petrásek
Jan
J
Opatrny
Zdenek
Z
D048430:Cell Shape / Q000187:drug effects; D002473:Cell Wall / Q000187:drug effects / Q000378:metabolism; D002478:Cells, Cultured; D002482:Cellulose / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D005875:Gibberellins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D011743:Pyrimidines / Q000494:pharmacology*; D014026:Nicotiana / Q000166:cytology* / Q000187:drug effects* / Q000378:metabolism
D005875:Gibberellins; D011743:Pyrimidines; C053577:ancymidol; D002482:Cellulose