title: Cardiac resynchronization therapy and valvular cardiomyopathy after corrective surgery.
abstract: Cardiac resynchronization therapy (CRT) has been shown to have clinical benefits in certain groups of patients with advanced heart failure (HF). However, patients with valvular cardiomyopathy are underrepresented in randomized clinical studies. The aim of this study was to assess the medium-term (i.e., at 6 months) effects of CRT in patients with HF exclusively due to valvular disease. The study included 40 consecutive patients who underwent CRT device implantation. At 6 months, there were improvements in functional class, left ventricular remodeling, and intraventricular dyssynchrony parameters in treated patients. In this particular subgroup of patients, the benefits of CRT were similar to those observed in patients with HF due to other etiologies.
authors.affiliation: Departamento de Cardiología y Cirugía Cardiovascular, Clínica Universitaria de Navarra, Pamplona, Navarra, Spain.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Macías
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Gavira
authors.forename: Sara
authors.initials: S
authors.lastname: Castaño
authors.forename: José
authors.initials: J
authors.lastname: Moreno
authors.forename: Eduardo
authors.initials: E
authors.lastname: Alegría
authors.forename: Ignacio
authors.initials: I
authors.lastname: García-Bolao
mesh_terms: D000368:Aged; D002304:Cardiac Pacing, Artificial; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000628:therapy*; D006349:Heart Valve Diseases / Q000150:complications*; D006801:Humans; D008297:Male