title: Juvenile polyposis syndrome affecting the stomach: a case report.
abstract: BACKGROUND
  Juvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition. Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon. In this case report we present an unusual case of JPS that presented with massive gastric polyposis requiring a total gastrectomy.
  
  
  METHODS
  A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding. Gastroscopy showed massive gastric polyposis with a large antral polyp that had prolapsed through the pylorus causing gastric outlet obstruction. Initially endoscopic polypectomy was performed, but due to progressive symptoms a total gastrectomy was then performed. Histology confirmed massive gastric juvenile polyposis.
  
  
  CONCLUSIONS
  Massive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome. This case illustrates important principles in managing this condition.
authors.affiliation: Cambridge Oesophagogastric surgery centre, Addenbrookes hospital, Cambridge, UK. stevekelly999@btinternet.com
authors.forename: Steven
authors.initials: S
authors.lastname: Kelly
authors.forename: Simon
authors.initials: S
authors.lastname: Dwerryhouse
authors.forename: Peter
authors.initials: P
authors.lastname: Safranek
authors.forename: Richard
authors.initials: R
authors.lastname: Hardwick