title: [pH-impedancemetry: clinical implications].
abstract: Gastroesophageal reflux disease is a common condition that requires no additional exam if the diagnosis is straightforward and no complications is suspected. pH monitoring is often used for atypical symptoms or if there is no response to therapy with proton pump inhibitors. This was considered for decades as a "gold standard", but it shows many limits, especially because it only measures acid exposure. pH-impedance monitoring is a new technique that detects all types of reflux (gas-liquid and acid-weakly acid) and evaluates the relationship between symptoms and reflux events. It identifies patients with symptoms related to weakly acid reflux, that is not detected by conventional pH monitoring.
authors.affiliation: Division de gastroentérologie et d'hépatologie, HUG, 1211 Geneve 14. david.bertolini@hcuge.ch
authors.forename: David
authors.initials: D
authors.lastname: Bertolini
authors.forename: Sabine
authors.initials: S
authors.lastname: Roman
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Dumonceau
mesh_terms: D002986:Clinical Trials as Topic; D004351:Drug Resistance; D017097:Electric Impedance; D050782:Esophageal pH Monitoring; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D015337:Multicenter Studies as Topic; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D054328:Proton Pump Inhibitors