title: A clinical review of outcomes of the multimodal treatment study of children with attention-deficit/hyperactivity disorder (MTA).
abstract: Over the past decade, the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder has provided a bewildering wealth of data (more than 70 peer-reviewed articles) addressing treatment-related questions for children with attention-deficit/hyperactivity disorder. However, the take-home messages for clinicians may not always be clear. Therefore, this article reviews key findings, including relative benefits of medication and behavioral treatments, long-term effects at 2 and 3 years, treatment mediators and moderators, preliminary delinquency and substance use outcomes, and growth suppression related to stimulant use. Appropriate interpretations of the findings and their limitations are discussed, and recommendations for clinical practice are derived.
authors.affiliation: Duke University Medical Center, 718 Rutherford Street, Durham, NC 27705, USA. dwmurray@duke.edu
authors.forename: Desiree W
authors.initials: DW
authors.lastname: Murray
authors.forename: L Eugene
authors.initials: LE
authors.lastname: Arnold
authors.forename: Jim
authors.initials: J
authors.lastname: Swanson
authors.forename: Karen
authors.initials: K
authors.lastname: Wells
authors.forename: Karen
authors.initials: K
authors.lastname: Burns
authors.forename: Peter
authors.initials: P
authors.lastname: Jensen
authors.forename: Lily
authors.initials: L
authors.lastname: Hechtman
authors.forename: Natalya
authors.initials: N
authors.lastname: Paykina
authors.forename: Lauren
authors.initials: L
authors.lastname: Legato
authors.forename: Tara
authors.initials: T
authors.lastname: Strauss
mesh_terms: D000124:Achievement; D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000453:epidemiology / Q000534:rehabilitation*; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000453:epidemiology / Q000534:rehabilitation; D001521:Behavior Therapy; D000697:Central Nervous System Stimulants / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003156:Community Mental Health Services; D015897:Comorbidity; D005500:Follow-Up Studies; D006801:Humans; D007604:Juvenile Delinquency / Q000534:rehabilitation / Q000706:statistics & numerical data; D012917:Social Adjustment; D012951:Socialization; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000534:rehabilitation; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants