title: [Local treatment for persistent inflammatory arthritis of the knee: intra-articular injection of glucocorticoids and bed rest].
abstract: Two studies evaluating treatment options for persistent mono-arthritis are discussed. In one study arthroscopic lavage plus intra-articular glucocorticoids was compared with arthroscopic lavage without glucocorticoids, and with joint aspiration plus glucocorticoids. Both intra-articular glucocorticoids and lavage have their merits, but glucocorticoids appear to be slightly more effective. In the second study radioactive Yttrium plus intra-articular glucocorticoids was compared with glucocorticoids alone. Yttrium provided little additional value. There are some indications that a period of strict bed rest after treatment is beneficial. Intra-articular glucocorticoids should not be administered more frequently than three times per year in the same joint.
authors.affiliation: Universitair Medisch Centrum Utrecht, Utrecht. j.w.j.bijlsma@umcutrecht.nl
authors.forename: J W J
authors.initials: JW
authors.lastname: Bijlsma
authors.forename: D B F
authors.initials: DB
authors.lastname: Saris
authors.forename: Z N
authors.initials: ZN
authors.lastname: Jahangier
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001168:Arthritis / Q000188:drug therapy / Q000628:therapy*; D001510:Bed Rest; D003131:Combined Modality Therapy; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007270:Injections, Intra-Articular; D007719:Knee Joint / Q000473:pathology*; D016896:Treatment Outcome; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D015021:Yttrium Radioisotopes