title: [Antibody response after immunization with a Salmonella Typhimurium live vaccine in dependence on the way of application].
abstract: In Germany now, the recognition of Salmonella infections in pig herds is based on three different commercial tests detecting antibodies against Salmonella-derived lipopolysaccharide (LPS). However, a serious disadvantage of these tests, used so far, is the restricted detection of antibodies belonging predominantly to the immunoglobulin class g (IgG). Therefore, a new test was developed to detect three Ig classes (IgM, IgG and IgA). Different constellations between the three Ig classes allow the evaluation of the current infection status of each pig. Under field conditions, this was proved in three different vaccination trials using a commercial Salmonella Typhimurium live vaccine.
authors.affiliation: Labor Diagnostik GmbH Leipzig, Leipzig.
authors.forename: Daniela
authors.initials: D
authors.lastname: Trepnau
authors.forename: Evelyn
authors.initials: E
authors.lastname: Ulrich
authors.forename: Reinhard
authors.initials: R
authors.lastname: Uhlig
authors.forename: Thomas
authors.initials: T
authors.lastname: Lindner
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Selbitz
authors.forename: Uwe
authors.initials: U
authors.lastname: Rösler
authors.forename: Jörg
authors.initials: J
authors.lastname: Gabert
authors.forename: Uwe
authors.initials: U
authors.lastname: Bergfeld
authors.forename: Karsten
authors.initials: K
authors.lastname: Fehlhaber
authors.forename: Werner
authors.initials: W
authors.lastname: Brabetz
authors.forename: Jörg
authors.initials: J
authors.lastname: Lehmann
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000918:Antibody Specificity; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D011897:Random Allocation; D012481:Salmonella Infections, Animal / Q000097:blood / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014613:Vaccines, Attenuated
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014613:Vaccines, Attenuated