title: Focal AF-ablation after pulmonary vein isolation in a patient with hypertrophic cardiomyopathy using cryothermal energy.
abstract: A 42-year-old man, with a history of hypertrophic cardiomyopathy (HCM), an electrocardiogram pattern of ventricular preexcitation typical for mutations in the PRKAG2 gene, and highly symptomatic paroxysmal drug-resistant atrial fibrillation (AF), underwent successful circumferential isolation of his pulmonary veins using a 28-mm double lumen cryoballoon. Because AF was still inducible with programmed stimulation, fractionated signals were targeted in the left atrium with a conventional cryocatheter. Ablation of an endocardial focus with fractionated potentials at the base of the left appendage terminated the episode and rendered AF noninducible. No recurrence of AF was observed during a 10-month follow-up period.
authors.affiliation: Clinical Electrophysiology Unit, Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands. y.vanbelle@erasmusmc.nl
authors.forename: Yves
authors.initials: Y
authors.lastname: Van Belle
authors.forename: Michelle
authors.initials: M
authors.lastname: Michels
authors.forename: Luc
authors.initials: L
authors.lastname: Jordaens
mesh_terms: D001281:Atrial Fibrillation / Q000150:complications / Q000601:surgery*; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000601:surgery*; D003452:Cryosurgery / Q000379:methods*; D006329:Heart Conduction System / Q000601:surgery*; D006801:Humans; D008297:Male; D011667:Pulmonary Veins / Q000601:surgery*; D016896:Treatment Outcome