New advances in stem cell biology: A perspective from gametogenesis.
Regeneration of adult tissues relies on a small population of adult stem cells located in a specialized microenvironment. The adult stem cells divide continuously to produce new stem cells, as well as differentiated daughter cells to replenish lost cells due to damage or aging. The molecular mechanisms controlling their ability to divide, self-renew and differentiate remain largely undiscovered. The Drosophila reproductive systems have proven to be excellent models to understand the basic mechanisms regulating stem cell function. This report summarizes some of the recent advances in this field that were presented at the 49(th) Drosophila Research Conference held in San Diego in April 2008.
Geng
Cuiyun
C
Stowers Institute for Medical Research, Kansas City, Missouri, USA. cuiyun123@gmail.com
D000818:Animals; D054337:Cell Dedifferentiation; D002454:Cell Differentiation; D002455:Cell Division; D016922:Cellular Senescence; D004330:Drosophila / Q000166:cytology*; D005718:Gametogenesis; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*