title: [Multiple familiar trichoepithelioma (Brooke's syndrome) : A rare autosomal dermatosis with possible periocular manifestation].
abstract: Brooke's syndrome is a rare autosomal dominant dermatosis characterized by multiple trichoepitheliomas, which preferentially arise in the face. Therapy consists of excisional surgery of larger tumors and for multiple lesions, dermal abrasion or laser therapy may be considered. Patients with Brooke's syndrome should be closely followed-up due to the possible development of malignant skin tumours. Here, we present a patient with Brooke's syndrome and report on the course of treatment.
authors.affiliation: Universitäts-Augenklinik der Medizinischen Fakultät Mannheim der Ruprecht-Karls-Universität Heidelberg, Mannheim, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Rensch
authors.forename: B
authors.initials: B
authors.lastname: Harder
authors.forename: M
authors.initials: M
authors.lastname: Goebeler
authors.forename: W
authors.initials: W
authors.lastname: Back
authors.forename: J B
authors.initials: JB
authors.lastname: Jonas
authors.forename: F
authors.initials: F
authors.lastname: Schlichtenbrede
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000151:congenital* / Q000175:diagnosis* / Q000628:therapy; D005134:Eye Neoplasms / Q000151:congenital* / Q000175:diagnosis* / Q000628:therapy; D005153:Facial Neoplasms / Q000151:congenital* / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008297:Male; D035583:Rare Diseases / Q000151:congenital / Q000175:diagnosis / Q000628:therapy; D013577:Syndrome