Burkholderia pseudomallei meningitis following inadequate treatment of melioidotic mycotic aneurysm.
We report a 64-year-old man presenting with meningitis caused by Burkholderia pseudomallei predisposed by persistent aortic graft infection following inadequate treatment of a melioidotic mycotic aneurysm. The relapse of melioidosis presenting as acute meningitis is a unique event. Successful treatment of deep-seated melioidosis can only be achieved when robust antimicrobial therapy is combined with appropriate surgical debridement.
Chlebicki
M P
MP
Department of Infectious Diseases, Singapore General Hospital, Outram Road, Singapore 169608. pchlebicki@hotmail.com
Kurup
A
A
Sin
Y K
YK
D000284:Administration, Oral; D000785:Aneurysm, Infected / Q000150:complications* / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001011:Aorta / Q000382:microbiology / Q000637:transplantation; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D019121:Burkholderia Infections / Q000209:etiology* / Q000382:microbiology* / Q000628:therapy; D016957:Burkholderia pseudomallei / Q000378:metabolism*; D004318:Doxycycline / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000150:complications* / Q000628:therapy*; D008581:Meningitis / Q000209:etiology* / Q000382:microbiology* / Q000628:therapy; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004318:Doxycycline