[Intravenous insulin: controversy on the adsorption process of infusion kits].
Insulin adsorption is a non-specific surface phenomenon that interferes with the patient's insulin demand. This literature review aimed at identifying the causes of insulin adsorption in intravenous solutions and the strategies used to reduce adsorption. Articles from Medical Literature and Retrieval System On Line (MEDLINE), Latin American and Caribbean Health Science Literature (LILACS), Cumulative Index to Nursing & Allied Health Literature (CINAHL) and Co-ordination and Improvement of Graduate People (CAPES) databases were used. Polypropylene flasks and in-line equipment without filter presented less adsorption, adsorption was maximum when the first looml of the solution were infused. Strategies used to minimize insulin adsorption pre-exposure of 50 to 100 solution flasks for 30-60 minutes, use of flasks with smaller internal surface, and short in-lines.
de Almeida Lima
Suziane
S
Unidade de Terapia Intensiva, Hospital Albert Einstein, São Paulo, Brasil.
Andreoli
Renata Luciane Fioratti
RL
Grossi
Sonia Aurora Alves
SA
Secoli
Silvia Regina
SR
D006801:Humans; D007275:Injections, Intravenous / Q000295:instrumentation; D007328:Insulin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007332:Insulin Infusion Systems
D007328:Insulin