Postoperative cognitive dysfunction after cardiac surgery.
Postoperative cognitive dysfunction is frequent in cardiac surgeries leading to major consequences. The physiopathological processes involved in this condition are still not completely elucidated, despite the multifactor character. Besides pre-operative factors such as age and education, some intra-operative factors are also of extreme importance. However, according to a vast literature on the subject, these factors are not capable to clarify the totality of the cases, taking us to a genetic base for this neurological sequel. In this revision, we briefly assess the factors involved in this cognitive dysfunction as well as discuss the pharmacotherapy in the prevention of this event.
Martin
José Fernando Vilela
JF
Departamento de Medicina, FAMERP. vilelamartin@uol.com.br
Melo
Renan Oliveira Vaz de
RO
Sousa
Letícia Pinheiro de
LP
D000367:Age Factors; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003072:Cognition Disorders / Q000188:drug therapy / Q000209:etiology*; D004522:Educational Status; D006801:Humans; D007431:Intraoperative Complications; D011184:Postoperative Period