title: Divergent ependymal tumor (ependymoblastoma/anaplastic ependymoma) of the posterior fossa: an uncommon case observed in a child.
abstract: We report a divergent ependymal tumor of the posterior fossa (ependymoblastoma/anaplastic ependymoma) observed in an 8-year-old boy. The tumor showed the histological pattern typical of an ependymoblastoma (tubular-papillary fetaloid architecture with stratification of the tumor cells) next to areas in which findings typical of an anaplastic ependymoma were detected. The immunohistochemical study confirmed our diagnostic suspicion, allowing us to establish a differential diagnosis with other entities such as medulloblastoma, medulloepithelioma, atypical rhabdoid/teratoid tumor, or metastases.
authors.affiliation: Department of Pathology, Hospital Universitario de Salamanca, Salamanca, Spain. jortiz@usal.es
authors.forename: Javier
authors.initials: J
authors.lastname: Ortiz
authors.forename: Alvaro
authors.initials: A
authors.lastname: Otero
authors.forename: Oscar
authors.initials: O
authors.lastname: Bengoechea
authors.forename: Jesús
authors.initials: J
authors.lastname: Gonçalves
authors.forename: Pablo
authors.initials: P
authors.lastname: Sousa
authors.forename: Javier
authors.initials: J
authors.lastname: Figols
authors.forename: Agustín
authors.initials: A
authors.lastname: Bullón
mesh_terms: D000367:Age Factors; D017668:Age of Onset; D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D001933:Brain Stem / Q000473:pathology / Q000503:physiopathology; D002531:Cerebellum / Q000473:pathology / Q000503:physiopathology; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D020546:Fourth Ventricle / Q000473:pathology* / Q000503:physiopathology; D006261:Headache / Q000209:etiology; D006801:Humans; D015192:Infratentorial Neoplasms / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000175:diagnosis; D019635:Neurosurgical Procedures; D016896:Treatment Outcome; D014839:Vomiting / Q000209:etiology
chemical_list: D014408:Biomarkers, Tumor