Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions.
A highly convergent [2+2+2] cyclotrimerization approach to anthracenes and 2-azaanthracenes has been developed. It allows for the facile introduction of the anthracene moiety on alkyne and nitrile bearing molecules and the rapid construction of compound arrays. This is showcased in the assembly of a collection of fluorophores and their photochemical evaluation.
Zou
Yan
Y
Department of Chemistry, North Carolina State University, Campus Box 8204, Raleigh, North Carolina 27695-8204, USA.
Young
Douglas D
DD
Cruz-Montanez
Alejandra
A
Deiters
Alexander
A
D000873:Anthracenes / Q000138:chemical synthesis* / Q000737:chemistry; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001554:Benzene / Q000737:chemistry; D002460:Cell Line; D003500:Cyclization; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry
D000873:Anthracenes; D001372:Aza Compounds; D005456:Fluorescent Dyes; D011725:Pyridines; C034020:anthracene; D001554:Benzene