title: Surgical management of unruptured intracranial aneurysms that are inappropriate for endovascular treatment: experience based on two academic centers.
abstract: OBJECTIVE
  To analyze the results of the surgical management of unruptured intracranial aneurysms (UIA) when coil embolization (CE) was considered first but deemed inappropriate by our multidisciplinary groups.
  
  
  METHODS
  In two institutions, all UIAs recommended for treatment were considered first for a CE procedure if accessibility, neck width, and fundus-to-neck ratio were appropriate. Patients with UIAs considered inappropriate for CE were to undergo a surgical clipping procedure. We reviewed the medical records of all patients who underwent surgical clipping between February 1996 and February 2006.
  
  
  RESULTS
  A total of 325 patients with 440 UIAs were treated. Of them, 149 patients were selected by our multidisciplinary staff for treatment by CE, and 176 patients with 238 UIAs were treated by 207 surgical procedures. Angiographic studies revealed complete occlusion in 95% and near total occlusion in 2.5% of surgically treated UIAs. No deaths related to surgery occurred. Sixteen patients (9.1%) experienced postoperative complications, four of which persisted 1 year after surgery (two cases of diplopia and two aphasic disorders). The 1-year morbidity rate was 2.2% (four of 176) by patient and 1.7% (four of 238) by aneurysm. For UIAs smaller than 10 mm in patients younger than 65 years old, the morbidity rate was 0.56%.
  
  
  CONCLUSIONS
  Our results gathered from two centers with the same management of UIAs show that SC remains a safe and effective treatment for UIAs even when CE is considered first.
authors.affiliation: Department of Neurosurgery, Bicêtre University Hospital, Bicêtre, France.
authors.forename: Nozar
authors.initials: N
authors.lastname: Aghakhani
authors.forename: Geraldo
authors.initials: G
authors.lastname: Vaz
authors.forename: Philippe
authors.initials: P
authors.lastname: David
authors.forename: Fabrice
authors.initials: F
authors.lastname: Parker
authors.forename: Pierre
authors.initials: P
authors.lastname: Goffette
authors.forename: Augustin
authors.initials: A
authors.lastname: Ozan
authors.forename: Christian
authors.initials: C
authors.lastname: Raftopoulos
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D015331:Cohort Studies; D000075202:Contraindications; D003399:Craniotomy; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures