title: Chitosan/polyethylene glycol diacrylate films as potential wound dressing material.
abstract: Michael addition reaction of Chitosan (CS) and polyethylene glycol diacrylate (PEGDA) was carried out successfully in acidic solution. Films with CS/PEGDA weight ratios from 100/0 to 0/100 in 10% increments were analyzed by Fourier transform infrared (FTIR) spectroscopy, Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD). Additionally, the films were characterized by measuring mechanical property, swelling property. The potential application of the CS/PEGDA film as wound dressing material was evaluated in vitro by using mouse fibroblasts (L929) as reference cell lines, indirect cytotoxicity assessment indicated that CS/PEGDA films were nontoxic to L929 cell.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Key Lab of Beijing City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Zhang
authors.forename: Dongzhi
authors.initials: D
authors.lastname: Yang
authors.forename: Jun
authors.initials: J
authors.lastname: Nie
mesh_terms: D000818:Animals; D001458:Bandages; D001672:Biocompatible Materials / Q000737:chemistry; D002448:Cell Adhesion; D045744:Cell Line, Tumor; D048271:Chitosan / Q000737:chemistry; D051379:Mice; D011092:Polyethylene Glycols / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001672:Biocompatible Materials; C437167:poly(ethylene glycol)diacrylate; D011092:Polyethylene Glycols; D048271:Chitosan