title: Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls.
abstract: A simple metal-free, step-economic and selective access to pyridines from readily available substrates is reported, involving a flexible 4 A molecular sieves promoted Michael addition initiated domino three-component reaction between a 1,3-dicarbonyl, a Michael acceptor and a synthetic equivalent of ammonia.
authors.affiliation: Aix-Marseille Université, Institut des Sciences Moléculaires de Marseille, Marseille Cedex 20, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Liéby-Muller
authors.forename: Christophe
authors.initials: C
authors.lastname: Allais
authors.forename: Thierry
authors.initials: T
authors.lastname: Constantieux
authors.forename: Jean
authors.initials: J
authors.lastname: Rodriguez
mesh_terms: D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D011725:Pyridines / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D007659:Ketones; D011725:Pyridines; D014867:Water