title: Multicentric Castleman's disease presenting with multiple nodes in lungs: a case report and literature review.
abstract: We report a rare multicentric Castleman's disease case whose lung manifestation is severe than any known report. This is a 64-year-old woman, she had repeated cough, fever and breathlessness for more than 1 year. CT imaging showed multiple small nodules in both the lungs at the first onset. Large nodes and masses in both the lungs evolved 1 year later. After three times of lung biopsies (one video-assisted thoracoscopic surgery and two CT-guided percutaneous transthoracic), she was finally diagnosed as multicentric Castleman's disease. She got surprising relief after combination chemotherapy in spite of her severe lung changes.
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 1 ShuaiFuYuan, WangFuJing, Beijing, China.
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 1 ShuaiFuYuan, WangFuJing, Beijing, China. hanbing-li@sina.com.
authors.forename: Bing
authors.initials: B
authors.lastname: Han
mesh_terms: D005871:Castleman Disease / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed