title: Multiple ocular abnormalities associated with trisomy 4p.
abstract: Ocular features associated with trisomy 4p have rarely been described. The authors have experienced multiple ocular abnormalities (bilateral cataracts, posterior synechiae, and posterior segment changes) associated with this chromosomal abnormality. It was presumed that these intraocular findings might be associated with the previous inflammatory process. In the current case, the patient recovered some useful vision after surgical removal of cataracts and intraocular lens implantations in both eyes. A detailed ophthalmic examination for patients with the autosomal imbalance is recom-mended.
authors.affiliation: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Samin
authors.initials: S
authors.lastname: Hong
authors.forename: Sung Yong
authors.initials: SY
authors.lastname: Kang
authors.forename: Gong Je
authors.initials: GJ
authors.lastname: Seong
authors.forename: Joo Youn
authors.initials: JY
authors.lastname: Shin
authors.forename: Chan Yun
authors.initials: CY
authors.lastname: Kim
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D000328:Adult; D001763:Blepharoptosis / Q000235:genetics; D002386:Cataract / Q000235:genetics; D002894:Chromosomes, Human, Pair 4; D004948:Esotropia / Q000235:genetics; D005124:Eye Abnormalities / Q000235:genetics*; D005143:Eyelids / Q000002:abnormalities; D005147:Facial Bones / Q000002:abnormalities; D005260:Female; D006801:Humans; D007621:Karyotyping; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification; D011859:Radiography; D012600:Scoliosis / Q000000981:diagnostic imaging / Q000235:genetics; D014314:Trisomy / Q000235:genetics*