The updated concept of genome and its implications in biotechnological research and molecular diagnostics.
We propose a short definition of
The full complement of genetic materials possessed by an intracellular parasite, a cell, or an organism. Accordingly, the human genome is the entire complement of inherited genetic materials possessed by an individual person, or possessed by a cell in an individual person. For higher species, the genomic makeup includes DNA in the nucleus and in the organelles regardless of the number of chromosomes and the homoplasmic or heteroplasmic status of the mitochondrial or chloroplastic DNA. Practically, GENOME can be referred to at the molecular, cellular, individual, and species levels, which has various implications in biotechnological research and molecular diagnostics.
Xiao
Li
L
Molecular Medicine Center, The Second Affiliated Hospital of Suzhou University, Suzhou, Jiangsu, 215004, China.
Saldivar
Juan-Sebastian
JS
Zhou
Cuilan
C
Chen
Chengli
C
Zhang
Jia
J
Sirois
Pierre
P
Li
Kai
K
D001709:Biotechnology / Q000639:trends; D016678:Genome; D015894:Genome, Human; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000639:trends; D012106:Research / Q000639:trends