title: Basal cell carcinoma and rhinophyma.
abstract: Rhinophyma, the end stage in the development of acne rosacea, is characterized by sebaceous hyperplasia, fibrosis, follicular plugging, and telangiectasia. Although it is commonly considered a cosmetic problem, it can result in gross distortion of soft tissue and airway obstruction. Basal cell carcinoma (BCC) is a rare finding in patients with rhinophyma. The objective of this study is to review the literature of BCC in rhinophyma and report on a case. A 70-year-old male presented with long-standing rosacea that resulted in a gross nasal deformity. The patient suffered from chronic drainage and recurrent infections that failed conservative treatment with oral and topical antibiotics. The patient decided to proceed with surgical intervention and underwent tangential excision and dermabrasion in the operating room. Since 1955 there have been 11 cases reported in the literature. In our case, the pathology report noted that the specimen had an incidental finding of a completely resected BCC. The patient did well postoperatively and at follow-up remains tumor-free. Despite the uncommon occurrence of BCC in resection specimens for rhinophyma, we recommend that all specimens be reviewed by a pathologist. If BCC is detected, re-excision may be necessary and careful follow-up is mandatory. Larger studies would be needed to determine the correlation between the 2 conditions.
authors.affiliation: Division of Plastic Surgery, University of Nevada School of Medicine, Las Vegas, NV 89102, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Leyngold
authors.forename: Ilya
authors.initials: I
authors.lastname: Leyngold
authors.forename: Peter R
authors.initials: PR
authors.lastname: Letourneau
authors.forename: William A
authors.initials: WA
authors.lastname: Zamboni
authors.forename: Himansu
authors.initials: H
authors.lastname: Shah
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D009666:Nose / Q000601:surgery; D009667:Nose Deformities, Acquired / Q000209:etiology / Q000601:surgery*; D009669:Nose Neoplasms / Q000473:pathology / Q000601:surgery*; D011230:Precancerous Conditions / Q000473:pathology / Q000601:surgery*; D012224:Rhinophyma / Q000150:complications / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome