title: Leukoencephalopathy with anterior temporal cysts due to congenital CMV infection diagnosed retrospectively.
abstract: Leukoencephalopathy with subcortical cysts has been described in a variety of conditions. However, few reports have highlighted congenital CMV as a cause of this imaging finding. We report a 1-year-old girl with developmental delay and sensorineural hearing loss whose MRI brain showed abnormal white matter and temporal cysts. Congenital CMV infection was diagnosed retrospectively by examination of dried blood spot from the newborn screening card.
authors.affiliation: Department of Pediatric Neurology, Children's University Hospital, Dublin 1, Ireland.
authors.forename: Declan
authors.initials: D
authors.lastname: O'Rourke
authors.forename: Lisa
authors.initials: L
authors.lastname: Bradley
authors.forename: Mary D
authors.initials: MD
authors.lastname: King
authors.forename: Stephanie
authors.initials: S
authors.lastname: Ryan
mesh_terms: D001921:Brain / Q000473:pathology* / Q000821:virology; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000151:congenital* / Q000175:diagnosis; D002658:Developmental Disabilities / Q000175:diagnosis / Q000821:virology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000151:congenital / Q000821:virology; D006801:Humans; D007223:Infant; D056784:Leukoencephalopathies / Q000473:pathology* / Q000821:virology*; D008279:Magnetic Resonance Imaging