title: [Thromboembolic events, abortions and a sick infant--unusual presentation of a vitamin deficiency].
abstract: Homocysteine is a risk factor for the development of thromboembolic disorders and vascular diseases. Furthermore, complications during pregnancy have been ascribed to hyperhomocysteinemia. We report on a pregnant woman being substituted by high doses folic acid for hyperhomocysteinemia. Thereby, the underlying pernicious anemia was masked. After birth, the neonate was exclusively breastfed. At the age of 5 months, the infant had to be admitted to hospital due to severe vitamin B(12)-deficiency. Using parenteral vitamin B(12) substitution, homocystein levels of the mother normalized and the infant throve and prospered again.
authors.affiliation: Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Charité, Campus Virchow Klinikum, Berlin, Deutschland. isrid.sturm@charite.de
authors.forename: I
authors.initials: I
authors.lastname: Sturm
authors.forename: J B
authors.initials: JB
authors.lastname: Hennermann
authors.forename: A
authors.initials: A
authors.lastname: von Arnim-Baas
authors.forename: P H
authors.initials: PH
authors.lastname: Driever
authors.forename: G
authors.initials: G
authors.lastname: Massenkeil
mesh_terms: D000026:Abortion, Habitual / Q000209:etiology*; D000328:Adult; D000752:Anemia, Pernicious / Q000175:diagnosis*; D001327:Autoimmune Diseases / Q000175:diagnosis*; D001942:Breast Feeding; D003937:Diagnosis, Differential; D005183:Failure to Thrive / Q000209:etiology*; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D005757:Gastritis, Atrophic / Q000175:diagnosis*; D006710:Homocysteine / Q000097:blood; D006801:Humans; D007223:Infant; D007437:Intrinsic Factor / Q000276:immunology; D008764:Methylmalonic Acid / Q000652:urine; D010295:Parietal Cells, Gastric / Q000276:immunology; D011247:Pregnancy; D013923:Thromboembolism / Q000209:etiology*; D014806:Vitamin B 12 Deficiency / Q000175:diagnosis*
chemical_list: D006710:Homocysteine; D008764:Methylmalonic Acid; D007437:Intrinsic Factor; D005492:Folic Acid