Pregnancy after solid organ transplantation.
For women with end-stage organ failure, transplantation is an established therapeutic option. Pregnancy after solid organ transplantation is no longer uncommon, especially with the recent advances in transplantation surgery and the availability of newer immunosuppressants. This article will review preconceptional counseling, common pregnancy complications, prenatal and intrapartum considerations, outcome by organ, immunosuppressant therapies, and neonatal outcomes based on data available from case series and voluntary registries. Some recommendations are provided to assist in the management of pregnancies after solid organ transplantation.
Mastrobattista
Joan M
JM
Department of Obstetrics, University of Texas Medical School, Houston, Texas 77030, USA. Joan.M.Mastrobattista@uth.tmc.edu
Gomez-Lobo
Veronica
V
D000328:Adult; D065095:Calcineurin Inhibitors; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation; D016031:Liver Transplantation; D016040:Lung Transplantation; D016377:Organ Transplantation; D016035:Pancreas Transplantation; D011184:Postoperative Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011251:Pregnancy Complications, Infectious / Q000628:therapy; D011256:Pregnancy Outcome; D014181:Transplantation Immunology
D065095:Calcineurin Inhibitors; D007166:Immunosuppressive Agents