Dystrophin knockdown mice suggest that early, transient dystrophin expression might be enough to prevent later pathology.
Duan
Dongsheng
D
Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, One Hospital Dr., Columbia, MO 65212, USA. duand@missouri.edu
D000818:Animals; D016189:Dystrophin / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D015870:Gene Expression; D015316:Genetic Therapy / Q000379:methods*; D007150:Immunohistochemistry; D051379:Mice; D008810:Mice, Inbred C57BL; D009137:Muscular Dystrophy, Animal / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000235:genetics; D013997:Time Factors; D014162:Transfection
D016189:Dystrophin; D034741:RNA, Small Interfering