Role of oxygen in wound healing.
Acute wounds are initially hypoxic. This state triggers the diffusion of oxygenated plasma from the surrounding intact tissue to the hypoxic area, and sets in train processes resulting in oxidative killing, angiogenesis and collagen synthesis.
Bishop
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Diving Diseases Research Centre, Hyperbaric Medical Centre, Plymouth, UK. alex.bishop@ddrc.org
D015687:Cell Hypoxia / Q000187:drug effects / Q000502:physiology; D003094:Collagen / Q000187:drug effects / Q000502:physiology; D006097:Granulation Tissue / Q000502:physiology; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy / Q000378:metabolism; D036341:Intercellular Signaling Peptides and Proteins / Q000502:physiology; D018919:Neovascularization, Physiologic / Q000187:drug effects / Q000502:physiology; D010100:Oxygen / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology; D010102:Oxygen Inhalation Therapy; D017382:Reactive Oxygen Species; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology; D014947:Wounds and Injuries / Q000188:drug therapy / Q000378:metabolism
D036341:Intercellular Signaling Peptides and Proteins; D017382:Reactive Oxygen Species; D003094:Collagen; D010100:Oxygen