Apoferritin protein cages: a novel drug nanocarrier for photodynamic therapy.
A methylene blue-encapsulated apoferritin complex shows cytotoxic effects on MCF-7 human breast adenocarcinoma cells when irradiated at the appropriate wavelength.
Yan
Fei
F
Department of Biomedical Engineering and Chemistry, Duke University, Durham, NC 27708, USA.
Zhang
Yan
Y
Yuan
Hsiang-kuo
HK
Gregas
Molly K
MK
Vo-Dinh
Tuan
T
D001052:Apoferritins / Q000737:chemistry*; D045744:Cell Line, Tumor; D004337:Drug Carriers / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D008751:Methylene Blue; D049329:Nanostructures / Q000737:chemistry* / Q000633:toxicity; D010778:Photochemotherapy / Q000379:methods*; D026082:Singlet Oxygen / Q000378:metabolism
D004337:Drug Carriers; D026082:Singlet Oxygen; D001052:Apoferritins; D008751:Methylene Blue