title: A long-survived case with solitary splenic metastasis from ovarian carcinoma.
abstract: A61-year-old postmenopausal woman with ovarian carcinoma was treated with two surgical operations and a series of platinum-based chemotherapy. A solitary metastasis into the splenic parenchyma was identified 33 months after the second surgery by abdominal computed tomography with an increased serum level of CA-125. She underwent a pancreaticosplenectomy and received platinum-based adjuvant chemotherapy continuously for 2 years. Her serum CA-125 level decreased to a normal range and she has lived without any recurrence for more than 10 years after the splenectomy. Solitary metastases from ovarian cancer into the splenic parenchyma are extremely rare. Among 18 cases previously reported, this present case shows the longest disease-free survival. Because these cases show favorable prognosis after splenectomy, surgical treatment should be considered along with adjuvant chemotherapy.
authors.affiliation: Kochi Medical School, Nankoku, Kochi, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Yoshioka
authors.forename: Takehiro
authors.initials: T
authors.lastname: Okabayashi
authors.forename: Isao
authors.initials: I
authors.lastname: Nishimori
authors.forename: Nagamasa
authors.initials: N
authors.lastname: Maeda
authors.forename: Takeki
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Takuhiro
authors.initials: T
authors.lastname: Kohsaki
authors.forename: Saburo
authors.initials: S
authors.lastname: Onishi
authors.forename: Takao
authors.initials: T
authors.lastname: Fukaya
authors.forename: Michiya
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hanazaki
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000556:secondary* / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000601:surgery*; D013156:Splenectomy / Q000379:methods*; D013160:Splenic Neoplasms / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome