Rhodium-catalyzed hydroformylation of cyclopropenes.
The first catalytic diastereo- and enantioselective hydroformylation of cyclopropenes was demonstrated. The reaction proceeds efficiently under very mild conditions and low catalyst loadings providing high yields of cyclopropylcarboxaldehydes. This novel methodology represents a convenient, atom-economic approach toward optically active cyclopropylcarboxaldehydes from readily available prochiral cyclopropenes.
Sherrill
William M
WM
Department of Chemistry, University of Kansas and Center for Environmentally Beneficial Catalysis, 1251 Wescoe Hall Drive, Malott Hall, Lawrence, Kansas 66045-7582, USA.
Rubin
Michael
M