Diazoniapolycyclic ions inhibit the activity of topoisomerase I and the growth of certain tumor cell lines.
Basili
Serena
S
University of Padova, Department of Pharmaceutical Sciences, Via Marzolo 5, 35131 Padova (Italy), Fax: (+39) 49-821-1452.
Basso
Giuseppe
G
Faccio
Anita
A
Granzhan
Anton
A
Ihmels
Heiko
H
Moro
Stefano
S
Viola
Giampietro
G
D045744:Cell Line, Tumor; D002626:Chemistry, Pharmaceutical / Q000379:methods; D004247:DNA / Q000737:chemistry; D004264:DNA Topoisomerases, Type I / Q000737:chemistry; D015195:Drug Design; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D007364:Intercalating Agents / Q000494:pharmacology; D007477:Ions; D019169:Jurkat Cells; D020014:K562 Cells; D008956:Models, Chemical; D009584:Nitrogen / Q000737:chemistry; D013816:Thermodynamics; D059004:Topoisomerase I Inhibitors
D007364:Intercalating Agents; D007477:Ions; D059004:Topoisomerase I Inhibitors; D004247:DNA; D004264:DNA Topoisomerases, Type I; D009584:Nitrogen