title: Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
authors.affiliation: University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB21EW, UK. ac313@cam.ac.uk
authors.forename: Alessio
authors.initials: A
authors.lastname: Ciulli
authors.forename: Duncan E
authors.initials: DE
authors.lastname: Scott
authors.forename: Michiyo
authors.initials: M
authors.lastname: Ando
authors.forename: Fernando
authors.initials: F
authors.lastname: Reyes
authors.forename: S Adrian
authors.initials: SA
authors.lastname: Saldanha
authors.forename: Kellie L
authors.initials: KL
authors.lastname: Tuck
authors.forename: Dimitri Y
authors.initials: DY
authors.lastname: Chirgadze
authors.forename: Tom L
authors.initials: TL
authors.lastname: Blundell
authors.forename: Chris
authors.initials: C
authors.lastname: Abell
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D055162:Biocatalysis; D003067:Coenzymes / Q000378:metabolism; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D009169:Mycobacterium tuberculosis / Q000201:enzymology*; D010453:Peptide Synthases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D011485:Protein Binding; D013449:Sulfonamides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology
chemical_list: D003067:Coenzymes; D004791:Enzyme Inhibitors; D013449:Sulfonamides; D000255:Adenosine Triphosphate; D010453:Peptide Synthases; C022318:pantothenate synthetase