[Changes in coagulation hemostasis in patients after coronary bypass surgery].
Changes in the coagulation link of hemostasis were studied in 37 patients who had undergone coronary bypass surgery using venous and arterial conduits and in 16 healthy individuals of the same age. The recordings of hemostasiograms were examined before and 14 days after surgery. Prior to coronary bypass surgery, the patients with ischemic heart disease were found to have coagulation hemostatic disorders as moderate hyperfibrinogenemia, fibrinolytic suppression, thrombinemia, and elevated D-dimer concentrations. Postoperatively, hypercoagulation substantially increased with suppressed fibrinolysis and decreased anticoagulants in the protein C system. In this connection, it is necessary to longer use anticoagulants in the postoperative period and to thoroughly monitor hemostasiogram recordings after their discontinuance.
Faĭl'
I L
IL
Dolgikh
V T
VT
Morova
N A
NA
Kireeva
N V
NV
Smirnov
D E
DE
Kovaleva
S V
SV
D000925:Anticoagulants / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology* / Q000517:prevention & control; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis; D006706:Homeostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000601:surgery; D017762:Nadroparin / Q000627:therapeutic use; D011486:Protein C / Q000502:physiology; D013917:Thrombin / Q000032:analysis
D000925:Anticoagulants; D005338:Fibrin Fibrinogen Degradation Products; D017762:Nadroparin; D011486:Protein C; C036309:fibrin fragment D; D005340:Fibrinogen; D013917:Thrombin; D001241:Aspirin