Simultaneous integrated coronary artery revascularization with long-term angiographic follow-up.
OBJECTIVE
Traditionally integrated coronary artery revascularization has been described as a 2-stage procedure. We evaluated the safety and feasibility of 1-stage, simultaneous, hybrid, robotically assisted coronary artery bypass grafting surgery and percutaneous coronary intervention.


METHODS
Fifty-eight patients underwent simultaneous, integrated coronary artery revascularization in an operating theater equipped with angiographic equipment. Forty-five patients were men. The mean age was 59 years. All internal thoracic arteries were harvested with robotic assistance. All anastomoses were manually constructed through a small anterior non-rib-spreading incision without cardiopulmonary bypass on the beating heart. Immediately after and within the same operative suite, both angiographic confirmation of graft patency and percutaneous coronary intervention were performed. In 52 patients therapeutic anticoagulation was achieved with the direct thrombin inhibitor bivalirudin.


RESULTS
There were no deaths or wound infections. There was 1 perioperative myocardial infarction. One patient had a stroke, and 3 patients required re-exploration for bleeding. The median lengths of intensive care and hospital stay were 1 and 4 days, respectively. All patients were alive and symptom free at follow-up (mean, 20.2 months; range, 1.1-40.8 months). Long-term angiographic follow-up in 54 patients showed 49 (91%) patent grafts (mean, 9.0 months; range, 4.3-40.8 months). There were 7 in-stent restenoses and 2 occluded stents.


CONCLUSIONS
For multivessel coronary artery disease, simultaneous integrated coronary artery revascularization with bivalirudin is safe and feasible. This approach enables complete multivessel revascularization with decreased surgical trauma and postoperative morbidity. Further studies are necessary to better determine patient selection and long-term outcomes.
Kiaii
Bob
B
Department of Surgery, University of Western Ontario, London Health Sciences Centre, University Hospital, Ivey Cardiac Centre, London, Ontario, Canada. bob.kiaii@lhsc.on.ca
McClure
R Scott
RS
Stewart
Peter
P
Rayman
Reiza
R
Swinamer
Stuart A
SA
Suematsu
Yoshihiro
Y
Fox
Stephanie
S
Higgins
Jennifer
J
Albion
Caroline
C
Kostuk
William J
WJ
Almond
David
D
Sridhar
Kumar
K
Teefy
Patrick
P
Jablonsky
George
G
Diamantouros
Pantelis
P
Dobkowski
Wojciech B
WB
Jones
Philip
P
Bainbridge
Daniel
D
Iglesias
Ivan
I
Murkin
John
J
Cheng
Davy
D
Novick
Richard J
RJ
D000925:Anticoagulants / Q000008:administration & dosage; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000379:methods*; D012371:Robotics; D016896:Treatment Outcome
D000925:Anticoagulants