title: Inhibition of biofilm formation using newly developed coating materials with self-cleaning properties.
abstract: The purpose of this study was to evaluate the inhibition of biofilm formation on newly developed coating materials with self-cleaning properties. A series of experimental coating materials containing fluoroalkylated acrylic acid oligomer (FAAO) were applied to resin composite substrates. The surfaces of the coating materials were analyzed by X-ray photoelectron spectroscopy (XPS) and contact angle measurement. Biofilm formation on the surface was assessed using Streptococcus mutans biofilms inside an oral simulator in vitro. The results indicated that an increase in the concentration of FAAO in the coating materials enhanced surface hydrophilicity and oil-repellency. Biofilm assays demonstrated that the amount of biofilm retained on the coating materials gradually decreased when the concentration of FAAO increased in the materials. It was concluded that the coating materials incorporated with FAAO possessed self-cleaning properties and displayed signs of inhibiting biofilm formation on their surfaces.
authors.affiliation: Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8549, Japan. hisoppu2003@yahoo.co.jp
authors.forename: Ayako
authors.initials: A
authors.lastname: Okada
authors.forename: Toru
authors.initials: T
authors.lastname: Nikaido
authors.forename: Masaomi
authors.initials: M
authors.lastname: Ikeda
authors.forename: Koichi
authors.initials: K
authors.lastname: Okada
authors.forename: Junichi
authors.initials: J
authors.lastname: Yamauchi
authors.forename: Richard M
authors.initials: RM
authors.lastname: Foxton
authors.forename: Hideo
authors.initials: H
authors.lastname: Sawada
authors.forename: Junji
authors.initials: J
authors.lastname: Tagami
authors.forename: Khairul
authors.initials: K
authors.lastname: Matin
mesh_terms: D000179:Acrylates / Q000737:chemistry; D000180:Acrylic Resins / Q000737:chemistry*; D001422:Bacterial Adhesion; D018441:Biofilms / Q000254:growth & development*; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000737:chemistry*; D017611:Fluorine Compounds / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D011108:Polymers / Q000737:chemistry; D013295:Streptococcus mutans; D013499:Surface Properties
chemical_list: D000179:Acrylates; D000180:Acrylic Resins; D020099:Coated Materials, Biocompatible; D017611:Fluorine Compounds; D011108:Polymers; C036658:acrylic acid