title: Haemophilia imaging: a review.
abstract: Haemophilia disorders are characterised by a blood coagulation anomaly leading to prolonged and excessive bleeding. Imaging provides an essential role in the investigation of both the musculoskeletal and the non-musculoskeletal complications of haemophilia. Our institution is home to a large tertiary referral centre for haemophilia treatment. Using our broad experience, we present a multi-modality pictorial review of the musculoskeletal manifestations of haemophilia, including haemophilic arthropathy, intra-muscular haemorrhage and haemophilic pseudotumour. The main imaging features of haemophilic arthropathy are described, including synovial hypertrophy, haemosiderin deposition, sub-chondral cyst formation and loss of joint space.
authors.affiliation: The Royal Free Hospital, London, UK. jodymaclachlan@hotmail.com
authors.forename: Jody
authors.initials: J
authors.lastname: Maclachlan
authors.forename: Antony
authors.initials: A
authors.lastname: Gough-Palmer
authors.forename: Rikin
authors.initials: R
authors.lastname: Hargunani
authors.forename: Joanna
authors.initials: J
authors.lastname: Farrant
authors.forename: Brian
authors.initials: B
authors.lastname: Holloway
mesh_terms: D001847:Bone Diseases / Q000175:diagnosis* / Q000209:etiology*; D003952:Diagnostic Imaging / Q000379:methods*; D006467:Hemophilia A / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis* / Q000209:etiology*