title: [How to raise efficacy of myringoplasty in extensive defects].
abstract: A comparative trial of miringoplasty efficacy with or without application of biosynthetic wound cover Biocom-1 was performed in 82 patients with sub- and total chronic defects or acute traumatic rupture of the tympanic membrane (58 and 24 patients, respectively). Better clinico-morphological and functional results were achieved in patients treated with application of Biocom-1 (p<0.05). Their stay in hospital was also shorter. Biocom-1 not only provides stable position of the neotympanic membrane but also protects against secondary infection.
authors.forename: V V
authors.initials: VV
authors.lastname: Diskalenko
authors.forename: L M
authors.initials: LM
authors.lastname: Kurmashova
mesh_terms: D006801:Humans; D009225:Myringoplasty / Q000379:methods*; D012720:Severity of Illness Index; D017768:Skin, Artificial; D018058:Tympanic Membrane Perforation / Q000601:surgery* / Q000628:therapy; D014945:Wound Healing