title: The accuracy of computed tomographic angiography for mapping the perforators of the deep inferior epigastric artery: a blinded, prospective cohort study.
abstract: BACKGROUND
  The deep inferior epigastric artery perforator flap is increasingly used for autologous breast reconstruction, with low donor-site morbidity cited as a major advantage of this operation. Preoperative imaging of the donor-site vasculature is frequently used as a further means of improving operative outcome. Computed tomographic angiography has been increasingly described as a preferred imaging modality; however, its formal evaluation has not been described in a clinical setting.
  
  
  METHODS
  A prospective, single-blind, cohort study was undertaken on 60 consecutive patients for whom deep inferior epigastric artery perforator flap surgery had been planned. Patients who did not undergo the procedure during the study period were excluded, with 42 patients ultimately included in the study. All computed tomographic angiography scans were obtained at a single institution. Perforators were mapped both on angiography and intraoperatively using a grid of 4-mm squares centered on the umbilicus. Only perforators larger than 1 mm were included in the study. All imaging findings were recorded by a single operator, and all intraoperative findings were recorded by the operating surgeon.
  
  
  RESULTS
  Computed tomographic angiography identified 280 major perforators in 42 patients. It was highly accurate, demonstrating 279 perforators recorded accurately, with one false-positive and one false-negative. Its sensitivity for mapping perforators was thus 99.6 percent, with a positive predictive value of 99.6 percent.
  
  
  CONCLUSIONS
  Computed tomographic angiography is highly accurate in identifying and mapping the perforators of the deep inferior epigastric artery. Its accuracy is superior to that of the previous modalities used in this role and suggests the usefulness of this technique before deep inferior epigastric artery perforator flap surgery for breast reconstruction.
authors.affiliation: Parkville, Victoria, Australia From the Jack Brockhoff Reconstructive Plastic Surgery Research Unit, University of Melbourne, and the Department of Radiology, Royal Melbourne Hospital.
authors.forename: Warren M
authors.initials: WM
authors.lastname: Rozen
authors.forename: Mark W
authors.initials: MW
authors.lastname: Ashton
authors.forename: Damien L
authors.initials: DL
authors.lastname: Stella
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Phillips
authors.forename: Damien
authors.initials: D
authors.lastname: Grinsell
authors.forename: G Ian
authors.initials: GI
authors.lastname: Taylor
mesh_terms: D000792:Angiography; D019074:Epigastric Arteries / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D016462:Mammaplasty; D011446:Prospective Studies; D016037:Single-Blind Method; D013524:Surgical Flaps / Q000098:blood supply*; D014057:Tomography, X-Ray Computed