Cortical spreading edema in persistent visual migraine aura.
We present imaging evidence of the spreading of cortical edema with reversibly restricted water diffusion from the left occipital to the temporoparietal cortex in persistent visual migraine aura in a 58-year-old man. The right-sided visual field defect lasting for 15 days was associated with discoupling of glucose metabolism and blood flow and the decreased apparent diffusion coefficient also suggested cytotoxic edema. At 8 weeks no signs were present, and magnetic resonance imaging became normal; therefore, long-lasting restricted cortical water diffusion, even if coupled with hypometabolism and edema, can be reversible in persistent visual migraine aura.
Bereczki
Dániel
D
Semmelweis University, Department of Neurology, Budapest, Balassa, U. L, H-1083, Hungary.
Kollár
József
J
Kozák
Norbert
N
Viszokay
Kornél
K
Barta
Zoltán
Z
Sikula
Judit
J
Magyar
Mária Tünde
MT
D000293:Adolescent; D001929:Brain Edema / Q000209:etiology* / Q000473:pathology; D002540:Cerebral Cortex / Q000503:physiopathology; D013181:Cortical Spreading Depression; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D020325:Migraine with Aura / Q000150:complications* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods