House dust mite allergens in domestic homes in Cheonan, Korea.
House dust mites produce inhalant allergens of importance to allergic patients. We measured the major group 1 allergens, Der p 1 and Der f 1, from the house dust mites Dermatophagoides pteronyssinus and Dermatophagoides farina, respectively in 100 randomly selected domestic homes from Cheonan, Korea. Dust samples were collected by vacuuming from the living room floor and 1 mattress in each home. Der p 1 and Der f 1 were measured by double monoclonal ELISA. Der p 1 levels were very low, with geometric mean levels for floors and mattresses being 0.11 microgram/g (range: 0.01-4.05) and 0.14 microgram/g (range: 0.01-30.0), respectively. Corresponding levels of Der f 1 were higher, 7.46 microgram/g (range: 0.01-262.9) and 10.2 microgram/g (range: 0.01-230.9) for floors and mattresses, respectively. D. farinae appears to be the dominant house dust mite in Cheonan.
Nam
Hae-Seon
HS
Department of Clinical Parasitology, School of Medicine, Soonchunhyang University, Cheonan 330-090, Korea.
Siebers
Robert
R
Lee
Sun-Hwa
SH
Park
Joon-Soo
JS
Kim
Yong-Bae
YB
Choi
Young-Jin
YJ
Lee
Sang-Han
SH
Crane
Julian
J
D000818:Animals; D039741:Antigens, Dermatophagoides / Q000276:immunology / Q000302:isolation & purification*; D060829:Arthropod Proteins; D001512:Bedding and Linens; D003546:Cysteine Endopeptidases; D004391:Dust / Q000032:analysis; D005430:Floors and Floorcoverings; D006798:Housing; D006801:Humans; D007723:Korea; D039981:Pyroglyphidae / Q000276:immunology*
D039741:Antigens, Dermatophagoides; D060829:Arthropod Proteins; D004391:Dust; D003546:Cysteine Endopeptidases; C451159:Dermatophagoides farinae antigen f 1; C451162:Dermatophagoides pteronyssinus antigen p 1