title: Spontaneous coronary artery dissection: case series and review.
abstract: Spontaneous coronary artery dissection (SCAD) is a rare but important cause of acute coronary syndromes. SCAD can cause unstable angina, acute myocardial infarction, and sudden death. Predisposing factors include atherosclerosis, the peripartum period, and structural and inflammatory conditions affecting the arterial wall. The diagnosis of coronary dissection is usually made by coronary angiography. Prompt diagnosis and treatment of patients with dissection improves survival. Therapeutic options include medical therapy, percutaneous coronary intervention, and surgery. We present a series of patients with spontaneous coronary artery dissection at our institution. The etiology, pathogenesis, diagnosis, treatment, and prognosis of patients with coronary dissection are reviewed.
authors.affiliation: Sinai Medical Center, The Zena and Michael A. Wiener Cardiovascular Institute, The Mt. Sinai Medical Center, Box 1030, One Gustave L. Levy Place, New York, NY 10029, USA. Mazullah.Kamran@msnyuhealth.org
authors.forename: Mazullah
authors.initials: M
authors.lastname: Kamran
authors.forename: Amrit
authors.initials: A
authors.lastname: Guptan
authors.forename: Monika
authors.initials: M
authors.lastname: Bogal
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003323:Coronary Aneurysm / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D003324:Coronary Artery Disease / Q000503:physiopathology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors