title: Consensus nomenclature for the human ArfGAP domain-containing proteins.
abstract: At the FASEB summer research conference on "Arf Family GTPases", held in Il Ciocco, Italy in June, 2007, it became evident to researchers that our understanding of the family of Arf GTPase activating proteins (ArfGAPs) has grown exponentially in recent years. A common nomenclature for these genes and proteins will facilitate discovery of biological functions and possible connections to pathogenesis. Nearly 100 researchers were contacted to generate a consensus nomenclature for human ArfGAPs. This article describes the resulting consensus nomenclature and provides a brief description of each of the 10 subfamilies of 31 human genes encoding proteins containing the ArfGAP domain.
authors.affiliation: Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA. rkahn@emory.edu
authors.forename: Richard A
authors.initials: RA
authors.lastname: Kahn
authors.forename: Elspeth
authors.initials: E
authors.lastname: Bruford
authors.forename: Hiroki
authors.initials: H
authors.lastname: Inoue
authors.forename: John M
authors.initials: JM
authors.lastname: Logsdon
authors.forename: Zhongzhen
authors.initials: Z
authors.lastname: Nie
authors.forename: Richard T
authors.initials: RT
authors.lastname: Premont
authors.forename: Paul A
authors.initials: PA
authors.lastname: Randazzo
authors.forename: Masanobu
authors.initials: M
authors.lastname: Satake
authors.forename: Anne B
authors.initials: AB
authors.lastname: Theibert
authors.forename: Maria L
authors.initials: ML
authors.lastname: Zapp
authors.forename: Dan
authors.initials: D
authors.lastname: Cassel
mesh_terms: D020727:ADP-Ribosylation Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism; D000818:Animals; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism; D003598:Cytoskeletal Proteins / Q000235:genetics / Q000378:metabolism; D020690:GTPase-Activating Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D005810:Multigene Family; D011487:Protein Conformation; D009626:Terminology as Topic
chemical_list: C507017:ACAP1 protein, human; C470574:AGAP1 protein, human; D048868:Adaptor Proteins, Signal Transducing; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; C106957:FYB1 protein, human; C485647:GIT1 protein, human; D020690:GTPase-Activating Proteins; C484407:KIFAP3 protein, human; C505827:MAP9 protein, human; D008869:Microtubule-Associated Proteins; D020727:ADP-Ribosylation Factors