Silent white matter lesion in linear scleroderma en coup de sabre.
We report a patient with linear scleroderma en coup de sabre without neurological symptoms despite the presence of large white matter lesions. The patient underwent 3.0-T magnetic resonance (MR) examinations including diffusion tensor imaging, time-resolved contrast-enhanced MR angiography, susceptibility-weighted imaging, and proton MR spectroscopy. These imaging findings suggested increased vascular permeability and microbleeding without abnormalities of metabolites. Our observation is consistent with vasculopathy and may be helpful in the proper diagnosis and treatment of linear scleroderma en coup de sabre.
Sakai
Mio
M
Department of Radiology, The Institute of Medical Science, University of Tokyo, Tokyo, Japan. s-mio@umin.ac.jp
Aoki
Shigeki
S
Inoue
Yusuke
Y
Ashida
Ryuichi
R
Yamada
Haruyasu
H
Kiryu
Shigeru
S
Inano
Sachiko
S
Mori
Harushi
H
Masutani
Yoshitaka
Y
Abe
Osamu
O
Ohtomo
Kuni
K
Nakamura
Hironobu
H
D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000473:pathology*