title: [Disseminated subcutaneous fat necrosis and elbow joint arthritis as a complication of pancreatitis].
abstract: BACKGROUND
  Intraabdominal fat necrosis of the retroperitoneum, mesenthery and omentum is a frequent complication of acute pancreatitis. Very rarely, during the disease multiple aseptic subcutaneous fat necrosis, polyarthritis, polyserositis, vasculitis, subcutaneous nodi and eosinophylia, isolated or in combination, may appear. They are known as "pancreatic disease syndrome".
  
  
  METHODS
  We presented a female patient, 43-year-old, in whom in the course of acute interstitial biliary pancreatitis had occur red multiple localized aseptic necrosis of subcutaneous fat tissue of extremities appeared mostly around the talocrural and wrist joints requiring multiple incision, as well as aseptic elbow joints arthritis requiring puncture of one elbow joint. The symptoms were followed by a prolonged febrility that settled within several weeks.
  
  
  CONCLUSIONS
  Localized disseminated fat necrosis around joints, arthritis of major joints, alone or with some of other symptoms of the "pancreatic disease syndrome" have to be considered as a probable sign of pancreatitis, even in the abscence of major abdominal symptoms.
authors.affiliation: Klinicki centar Srbije, Institut za bolesti digestivnog sistema, Beograd, Srbija. ngrubor@hotmail.com
authors.forename: Radoje
authors.initials: R
authors.lastname: Colović
authors.forename: Nikica
authors.initials: N
authors.lastname: Grubor
authors.forename: Vladimir
authors.initials: V
authors.lastname: Radak
authors.forename: Natasa
authors.initials: N
authors.lastname: Colović
authors.forename: Vitomir
authors.initials: V
authors.lastname: Ranković
authors.forename: Stojan
authors.initials: S
authors.lastname: Latincić
authors.forename: Slavko
authors.initials: S
authors.lastname: Matić
mesh_terms: D000208:Acute Disease; D000328:Adult; D001168:Arthritis / Q000209:etiology*; D004551:Elbow Joint; D005218:Fat Necrosis / Q000209:etiology*; D005260:Female; D006801:Humans; D010195:Pancreatitis / Q000150:complications*; D050151:Subcutaneous Fat