title: Radiofrequency ablation for the treatment of obstructive sleep apnea: a meta-analysis.
abstract: OBJECTIVE
  Recent studies suggest that radiofrequency ablation (RFA) is a treatment option for patients with obstructive sleep apnea (OSA). This study investigates the effectiveness of RFA in treating OSA using a critical literature review and meta-analysis.
  
  
  METHODS
  Critical literature review and meta-analysis.
  
  
  METHODS
  Two independent searches of PubMed 1966-present were performed to identify publications pertaining to RFA and OSA. Effectiveness of the procedure was measured by comparing the Epworth Sleepiness Scale (ESS), respiratory disturbance index (RDI), and lowest O2 saturation before and after tissue ablation.
  
  
  RESULTS
  Sixteen studies met the inclusion criteria. The study found a 31% reduction in short-term ESS (odds ratios (OR) 0.69, 95% confidence interval (CI) 0.63-0.75), which was maintained beyond 12 months (OR 0.68, 95% CI 0.43-0.73). Likewise, RFA resulted in a 31% reduction in short term (<12 month) (OR 0.69, 95% CI 0.61-0.77) and 45% reduction (OR 0.55, 95% C.I. 0.45-0.72) in long-term (>24 month) RDI levels. Short-term results of the lowest O2 saturations failed to demonstrate improvement (OR 1.03, 95% CI 0.88-1.20).
  
  
  CONCLUSIONS
  RFA seems to be a clinically effective tool that reduces ESS scores and RDI levels in patients with OSA syndrome. The procedure should be considered a valid treatment option for patients who refuse or are unable to tolerate continuous positive airway pressure.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA. farrarj@musc.edu
authors.forename: Joshua
authors.initials: J
authors.lastname: Farrar
authors.forename: James
authors.initials: J
authors.lastname: Ryan
authors.forename: Eric
authors.initials: E
authors.lastname: Oliver
authors.forename: M Boyd
authors.initials: MB
authors.lastname: Gillespie
mesh_terms: D017115:Catheter Ablation; D006801:Humans; D010160:Palate, Soft / Q000601:surgery; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D014059:Tongue / Q000601:surgery