Extensive atypical genital herpes simplex type 2 infection as an initial manifestation of acquired immune deficiency syndrome.
We present a case of an ulcerative lesion of the genitalia starting one year before in a 33-year-old man. Histopathologic examination revealed herpes virus infection, which suggested the existence of cell-mediated immunodeficiency. Human immunodeficiency virus (HIV) infection was confirmed by ELISA and Western blot test. The patient was treated with intravenous acyclovir, which led to complete remission. We underline the importance of early detecting and diagnosing patients with similar clinical manifestation as a sign of significant underlying immunodeficiency.
Rigopoulos
Dimitris
D
Department of Dermatology and Venereology, Andreas Sygros University Hospital, 5 Ionos Dragoumi Str., Athens, Greece.
Malouchou
Katerina
K
Alevizos
Alevizos
A
Larios
George
G
Papadogiorgak
Heleni
H
Lima
Katerina
K
Antoniou
Christina
C
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D015153:Blotting, Western; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D006558:Herpes Genitalis / Q000175:diagnosis* / Q000188:drug therapy; D018258:Herpesvirus 2, Human / Q000187:drug effects / Q000472:pathogenicity*; D006801:Humans
D000998:Antiviral Agents; D000212:Acyclovir