title: Brain scintigraphy with 99mTc-tetrofosmin for the differential diagnosis of a posterior fossa tumor.
abstract: A 60-year-old woman harbouring a tumour in the cerebellum. Anatomic brain imaging by computed tomography and magnetic resonance imaging were not conclusive of the lesion's nature. Imaging by (99m)Tc-tetrofosmin single-photon emission tomography (SPET) showed increased radiotracer accumulation in the lesion, indicating a vascular supply, membrane permeability and cellular metabolic activity, which is suggested to facilitate tracer uptake by lesions located in the posterior fossa. The patient underwent surgery and haemangioblastoma was confirmed by histology. Differential diagnosis is discussed. (99m)Tc-tetrofosmin scintiscan contributed to diagnostic information.
authors.affiliation: Department of Neurosurgery, University of Ioannina, School of Medicine, Ioannina, Greece. alexiougrg@yahoo.gr
authors.forename: George A
authors.initials: GA
authors.lastname: Alexiou
authors.forename: Spyridon
authors.initials: S
authors.lastname: Tsiouris
authors.forename: Spyridon
authors.initials: S
authors.lastname: Voulgaris
authors.forename: Mihalis
authors.initials: M
authors.lastname: Doukas
authors.forename: Ann
authors.initials: A
authors.lastname: Goussia
authors.forename: Athanasios P
authors.initials: AP
authors.lastname: Kyritsis
authors.forename: Konstantinos S
authors.initials: KS
authors.lastname: Polyzoidis
authors.forename: Andreas D
authors.initials: AD
authors.lastname: Fotopoulos
mesh_terms: D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging*; D002531:Cerebellum / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D018325:Hemangioblastoma / Q000000981:diagnostic imaging*; D006801:Humans; D015192:Infratentorial Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin