New secoiridoid glycosides from the roots of Picrorhiza scrophulariiflora.
Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyses and comparisons with data from related compounds. A pilot pharmacological study showed that picrogentiosides A (1) and B (2) have an immunomodulatory effect in vitro.
Zou
Lian-Chun
LC
College of Chemistry, Jilin University, Changchun 130062, P.R. China. wdc9928@jluhp.edu.cn
Zhu
Tong-Fei
TF
Xiang
Hua
H
Yu
Lu
L
Yan
Zhi-Hui
ZH
Gan
Shu-Cai
SC
Wang
Da-Cheng
DC
Zeng
Sheng
S
Deng
Xu-Ming
XM
D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D032261:Picrorhiza / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry*
D006027:Glycosides; D039823:Iridoids; D010936:Plant Extracts