title: Lactonizations of carboxylic acid-substituted 3-fluorodihydropyridines with electrophiles: peculiar behaviour of F(+).
abstract: Whereas for 3-fluorodihydropyridine-substituted carboxylic acids electrophiles such as HCl, iodine, bromine and peracids discriminate the double bond lacking and that bearing fluorine, no such differentiation took place in the case of electrophilic fluorine since the formation of both mono and gem-difluorolactones took place.
authors.affiliation: Laboratoire de Chimie Organique, Université Pierre et Marie Curie, 75252, Paris cedex 5, France. henri.rudler@upmc.fr
authors.forename: Henri
authors.initials: H
authors.lastname: Rudler
authors.forename: Andrée
authors.initials: A
authors.lastname: Parlier
authors.forename: Louis
authors.initials: L
authors.lastname: Hamon
authors.forename: Patrick
authors.initials: P
authors.lastname: Herson
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Daran
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D004095:Dihydropyridines / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular
chemical_list: D002264:Carboxylic Acids; D004095:Dihydropyridines; D007783:Lactones