title: Allograft and bone morphogenetic proteins: an overview.
abstract: Allograft is frequently used in orthopaedic and trauma surgery. On top of safety issues its biological activity is limited also due to processing. Consequently, the combination of allograft with osteoinductive substances may increase its effectiveness and decrease failure rates. In particular Bone Morphogenetic Proteins (BMPs) seem to be a promising partner for clinical applications. This overview focuses on the combined application of allograft/BMPs. Current points of view from available literature are summarized.
authors.affiliation: Department of Surgery/Traumatology, University Nijmegen Medical Center, Nijmegen, The Netherlands. T.Blokhuis@chir.umcn.nl
authors.forename: T J
authors.initials: TJ
authors.lastname: Blokhuis
authors.forename: T
authors.initials: T
authors.lastname: Lindner
mesh_terms: D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D003131:Combined Modality Therapy; D017102:Fracture Healing; D050723:Fractures, Bone / Q000628:therapy*; D006801:Humans
chemical_list: D019485:Bone Morphogenetic Proteins