title: Adaptation of the protocol for determining in vitro the sun protection factor of anti-solar sticks.
abstract: Apart from the protection offered by clothing, the application of sunscreen products suited to each type of skin constitutes one way for decreasing the frequency of skin cancers nowadays. After having adapted an in vitro method for determining the efficacy of sunscreens in emulsion form, we wished to transpose this technique by adapting it for the anti-solar sticks for the evaluation of sun protection factor (SPF) using a spectrophotometer equipped with an integrating sphere. To do this, we tested 14 products in the market as well as sticks that we ourselves fabricated in the laboratory. In a base common to all of these sticks, we added organic (13 filters tested) and inorganic (two filters tested, titanium dioxide and zinc oxide) to their maximum permitted concentration in the European Union. In parallel, emulsions containing the same filters at the same percentage of use were studied; to be in keeping with the results on the products packaging on the one hand, and with the results obtained for the emulsion form on the other hand, we were able to determine the optimal mass which needed to be placed on the support used the in vitro test to determine the SPF.
authors.affiliation: Université de Nantes, Nantes Atlantique Universités, LPiC, MMS, EA2160, Faculty of Pharmacy, 1 rue G. Veil - BP 53508, Nantes F-44000, France.
authors.forename: B
authors.initials: B
authors.lastname: Choquenet
authors.forename: C
authors.initials: C
authors.lastname: Couteau
authors.forename: E
authors.initials: E
authors.lastname: Paparis
authors.forename: L J M
authors.initials: LJ
authors.lastname: Coiffard
mesh_terms: D004304:Dosage Forms; D066298:In Vitro Techniques; D011837:Radiation-Protective Agents / Q000008:administration & dosage*; D013472:Sunlight
chemical_list: D004304:Dosage Forms; D011837:Radiation-Protective Agents