Ankle-brachial index and extent of atherosclerosis in patients from the Middle East (the AGATHA-ME study): a cross-sectional multicenter study.
To assess the extent of atherothrombosis and the use of the ankle-brachial index (ABI) in populations from the Middle East, we conducted a multicenter study similar to AGATHA (a Global Atherothrombosis Assessment), AGATHA-ME, which included 1341 patients from 18 centers from 5 countries (United Arab Emirates, Kuwait, Qatar, Bahrain, and Oman). Patients were assigned to 2 groups: the with-disease and at-risk groups. Abnormal ABI (< or =0.9) was seen in 31.5% of at-risk patients and 28.2% of with-disease patients. Patients with peripheral arterial disease had the highest frequency of abnormal ABI (77.6%), with 97.8 negative predictive value. The AGATHA-ME study confirms that atherothrombosis disease often occurs at more than 1 site. The ABI is related to the risk factor profile and to the site and extent of atherothrombosis. Gender and diabetes mellitus are associated with the worst parameters.
El-Menyar
Ayman
A
Department of Cardiology and Cardiovascular Surgery, Medical Research Center Hamad Medical Corporation, Qatar.
Amin
Haitham
H
Rashdan
Ibrahim
I
Souliman
Kadhim
K
Deleu
Dirk
D
Saadat
Kamran
K
Al Mahmeed
Wael
W
Bakir
Sharif
S
Wasif
Adel
A
Ben Brek
Azan
A
Bazargani
Nooshin
N
Ahmed Abdel Aziz
Singh
Rajvir
R
Hatou
Iman
I
Mahmoud
Hisham
H
Al Suwaidi
Jassim
J
D000368:Aged; D055109:Ankle Brachial Index; D018912:Arabs; D050197:Atherosclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000208:ethnology*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000208:ethnology; D003430:Cross-Sectional Studies; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008877:Middle East; D012307:Risk Factors