title: Serum carcinoembryonic antigen level and pleural lavage cytology in woman with non-small cell lung cancer.
abstract: BACKGROUND
  The prognostic impact of serum carcinoembryonic antigen (CEA) levels and pleural lavage cytology (PLC) in female patients with non-small cell lung cancer (NSCLC) were examined.
  
  
  METHODS
  A consecutive series of 122 women with NSCLC who underwent surgical resection and PLC were included in the study.
  
  
  RESULTS
  The 5-year survival rate of patients with preoperative serum normal and elevated CEA levels was 86.79 % and 58.46 %, respectively ( P = 0.0032). Positive PLC was present in 9/122 (7.38 %) of patients. The 5-year survival rate of patients with positive PLC findings was 33.33 %, which was significantly poor compared with that of patients with negative findings (83.16 %, P = 0.0010). Multivariate analysis indicated that pN status, preoperative serum CEA levels and PLC findings were independent prognostic factors.
  
  
  CONCLUSIONS
  Preoperative serum CEA level and PLC findings were independent prognostic factors for female patients with NSCLC.
authors.affiliation: Surgery II, University of Miyazaki, Miyazaki, Japan. mtomita@med.miyazaki-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Tomita
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Ayabe
authors.forename: T
authors.initials: T
authors.lastname: Onitsuka
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood*; D002289:Carcinoma, Non-Small-Cell Lung / Q000276:immunology* / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000276:immunology* / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008197:Lymph Node Excision; D008875:Middle Aged; D035422:Pleural Cavity / Q000473:pathology*; D011013:Pneumonectomy; D012189:Retrospective Studies; D007507:Therapeutic Irrigation; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002272:Carcinoembryonic Antigen