title: Prevalence of the human papillomavirus in an inner-city indigent population with previously normal Pap tests.
abstract: OBJECTIVE
  To determine the prevalence of human papillomavirus (HPV) in our inner-city indigent population (clinic population) of women with previously normal Pap tests and to identify any associated risk factors.
  
  
  METHODS
  A prospective cohort of 187 women between the ages of 15 and 49 years, with previously normal Pap tests, was recruited from a university affiliated outpatient clinic. A demographic questionnaire of social and sexual history was elicited, and ThinPrep cytology (Cytyc, Marlborough, MA) and HPV Digene Hybrid Capture II results (Digine, Gaithersburg, MD) were obtained.
  
  
  RESULTS
  The prevalence of HPV in our primarily Hispanic clinic population was 21%. The mean age of women with HPV was 28.9 years and those without were 32.1 years (p <.046). In women with HPV, 24% had abnormal Pap tests, whereas in those without HPV, 5% had abnormal Pap tests (p <.001). Women who were older and parous were less likely to have HPV (7.5%; p <.024). The presence of HPV was not influenced by sexual behaviors, sexually transmitted diseases, smoking, race, or contraceptive use.
  
  
  CONCLUSIONS
  The prevalence of HPV in an inner-city indigent population, despite previously normal cytology, was consistent with earlier reported rates of HPV. Our data suggest that younger, nulliparous women have a high prevalence of HPV.
authors.affiliation: Department of Obstetrics and Gynecology, Hartford Hospital, Hartford, CT 06102, USA.
authors.forename: Joelene
authors.initials: J
authors.lastname: Werden
authors.forename: Peter F
authors.initials: PF
authors.lastname: Schnatz
authors.forename: Srinivas
authors.initials: S
authors.lastname: Mandavilli
authors.forename: Gretchen
authors.initials: G
authors.lastname: Allen
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Murphy
authors.forename: John F
authors.initials: JF
authors.lastname: Greene
authors.forename: James F X
authors.initials: JF
authors.lastname: Egan
authors.forename: Joel I
authors.initials: JI
authors.lastname: Sorosky
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002584:Cervix Uteri / Q000821:virology*; D003237:Connecticut / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000453:epidemiology*; D010298:Parity; D011203:Poverty; D011247:Pregnancy; D015995:Prevalence; D014505:Urban Population / Q000706:statistics & numerical data*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*; D014626:Vaginal Smears; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology*