title: Hydrogenation of hindered ketones catalyzed by a silica-supported compact phosphine-Rh system.
abstract: A heterogeneous mono(phosphine)-Rh catalyst system silica-SMAP-Rh(OMe)(cod), where silica-SMAP stands for a caged, compact trialkylphosphine (SMAP) supported on silica gel, showed broad applicability toward the hydrogenation of hindered ketones. Doubly alpha-branched ketones such as diisopropyl ketone was hydrogenated under nearly atmospheric conditions. Di-tert-butyl ketone could be hydrogenated under more forcing conditions.
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
authors.forename: Soichiro
authors.initials: S
authors.lastname: Kawamorita
authors.forename: Go
authors.initials: G
authors.lastname: Hamasaka
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Ohmiya
authors.forename: Kenji
authors.initials: K
authors.lastname: Hara
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fukuoka
authors.forename: Masaya
authors.initials: M
authors.lastname: Sawamura