[An ionic determination of the insulinotropic action of insulin: not everyone agrees].
A recent model concerning the ionic determinants involved in the insulinotropic action of nutrients, namely an anion channel hypothesis, is presented, and selected experimental findings in support of such a model, are reviewed.
Malaisse
W J
WJ
Laboratoire d'Hormonologie Expérimentale, Faculté Médecine, ULB.
D001639:Bicarbonates / Q000378:metabolism; D002712:Chlorides / Q000502:physiology; D004032:Diet; D004734:Energy Metabolism; D006801:Humans; D007328:Insulin / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008954:Models, Biological; D010710:Phosphates / Q000502:physiology
D001639:Bicarbonates; D002712:Chlorides; D007328:Insulin; D007473:Ion Channels; D010710:Phosphates