title: Human herpesvirus 6 meningoradiculitis treated with intravenous immunoglobulin and valganciclovir.
abstract: Human herpesvirus 6 (HHV-6) is being increasingly associated with multiple neurological conditions. The authors report the case of a 26-year-old man with subacute meningoradiculitis initially treated with intravenous immunoglobulin. The cerebrospinal fluid (CSF) showed pleocytosis and polymerase chain reaction (PCR) was positive for HHV-6 type B DNA in the CSF and peripheral blood. He was subsequently treated with valganciclovir with near resolution of his symptoms.
authors.affiliation: Department of Neurology, Albert Einstein College of Medicine, Beth Israel Medical Center, 10 Union Square East, New York, NY 10003, USA. ckaram@chpnet.org
authors.forename: Chafic
authors.initials: C
authors.lastname: Karam
authors.forename: Manuel
authors.initials: M
authors.lastname: Revuelta
authors.forename: Daniel
authors.initials: D
authors.lastname: Macgowan
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D004279:DNA, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D015774:Ganciclovir / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015654:Herpesvirus 6, Human; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007964:Leukocytosis / Q000134:cerebrospinal fluid; D008297:Male; D008581:Meningitis / Q000628:therapy* / Q000821:virology; D016133:Polymerase Chain Reaction; D011843:Radiculopathy / Q000628:therapy* / Q000821:virology; D019349:Roseolovirus Infections / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome; D000077562:Valganciclovir
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D016756:Immunoglobulins, Intravenous; D000077562:Valganciclovir; D015774:Ganciclovir