Role of glutathione S-transferase (GSTM1) gene polymorphism in development of uterine fibroids.
Glutathione S-transferase (GSTM1) plays an important role in the excretion of catechol estrogens and is therefore a candidate marker for fibroids. However, this case-control study demonstrated no association between GSTM1 polymorphism and the risk of leiomyoma in Brazilian women.
de Oliveira
Emerson
E
Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil. emerson.gineco@unifesp.epm.br
de Aquino Castro
Rodrigo
R
Vieira Gomes
Mariano Tamura
MT
Cotrim Guerreiro da Silva
Ismael Dale
ID
Baracat
Edmund Chada
EC
Rodrigues de Lima
Geraldo
G
Ferreira Sartori
Marair Gracio
MG
Batista Castello Girão
Manoel João
MJ
D001938:Brazil; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D007889:Leiomyoma / Q000208:ethnology / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012307:Risk Factors
D005982:Glutathione Transferase