An easy entry to optically active alpha-amino phosphonic acid derivatives using phase-transfer catalysis (PTC).
The unprecedented use of phase-transfer catalysis (PTC) in an asymmetric hydrophosphonylation reaction allows the obtainment of a range of optically active alpha-amino phosphonic acid derivatives directly from alpha-amido sulfones.
Fini
Francesco
F
Department of Organic Chemistry A. Mangini, University of Bologna, V. Risorgimento 4, 40136, Bologna, Italy.
Micheletti
Gabriele
G
Bernardi
Luca
L
Pettersen
Daniel
D
Fochi
Mariafrancesca
M
Ricci
Alfredo
A
D002384:Catalysis; D007097:Imines / Q000737:chemistry; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D044367:Phase Transition; D013237:Stereoisomerism; D013450:Sulfones / Q000737:chemistry*
D007097:Imines; D063065:Organophosphonates; D013450:Sulfones