Transposing phytochrome into the nucleus.
To control many physiological responses, phytochromes directly modulate gene expression. A key regulatory event in this signal transduction pathway is the light-controlled translocation of the photoreceptor from the cytoplasm into the nucleus. Recent publications are beginning to shed light on the molecular mechanisms underlying this central control point. Interestingly, there is a specific mechanism for phytochrome A (phyA) nuclear accumulation. The dedicated phyA nuclear import pathway might be important for the distinct photosensory specificity of this atypical phytochrome. Recent studies in the field also provide a starting point for investigating how the different subcellular pools of phytochrome can control distinct responses to light.
Fankhauser
Christian
C
Centre for Integrative Genomics, University of Lausanne, Genopode Building, Lausanne, Switzerland. christian.fankhauser@unil.ch
Chen
Meng
M
D001692:Biological Transport; D002467:Cell Nucleus / Q000378:metabolism*; D006706:Homeostasis; D008954:Models, Biological; D010834:Phytochrome / Q000378:metabolism*; D051942:Phytochrome A / Q000378:metabolism; D051939:Phytochrome B / Q000378:metabolism; D018521:Plant Physiological Phenomena
D051942:Phytochrome A; D010834:Phytochrome; D051939:Phytochrome B