[The use of dipyridamole (curantyl) in combination with alpha-lipoic acid in the treatment of diabetic neuropathy with retinopathy].
Fifty-four patients diagnosed with distal sensomotor diabetic polyneuropathy of low extremities have been studied. All patients suffered from diabetes mellitus type 2 and had signs of retinopathy. It has been shown that berlition in dosage 300 mg twice daily for 3 months exerts a significant positive effect on the state of sensory and motor functions as well as neurophysiologic disturbances. The effect is increased significantly, especially in the sensory sphere (tactile, temperature and pain sensitivity), when the drug is used in combination with curantyl in dosage 50 mg twice daily for 3 months. The positive influence of this combination on the development of retinopathy is also observed.
Al-Zamil
M Kh
MKh
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use*; D003929:Diabetic Neuropathies / Q000150:complications* / Q000188:drug therapy*; D003930:Diabetic Retinopathy / Q000150:complications* / Q000188:drug therapy*; D004176:Dipyridamole / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008063:Thioctic Acid / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000975:Antioxidants; D014665:Vasodilator Agents; D004176:Dipyridamole; D008063:Thioctic Acid