title: From diversity to delivery: the case of the Indian Genome Variation initiative.
abstract: India currently has the world's second-largest population along with a fast-growing economy and significant economic disparity. It also continues to experience a high rate of infectious disease and increasingly higher rates of chronic diseases. However, India cannot afford to import expensive technologies and therapeutics nor can it, as an emerging economy, emulate the health-delivery systems of the developed world. Instead, to address these challenges it is looking to biotechnology-based innovation in the field of genomics. The Indian Genome Variation (IGV) consortium, a government-funded collaborative network among seven local institutions, is a reflection of these efforts. The IGV has recently developed the first large-scale database of genomic diversity in the Indian population that will facilitate research on disease predisposition, adverse drug reactions and population migration.
authors.affiliation: McLaughlin-Rotman Centre for Global Health, Program on Life Sciences, Ethics and Policy, University Health Network and University of Toronto, MaRS Centre, South Tower, Suite 406, 101 College Street, Toronto, Ontario M5G 1L7, Canada.
authors.forename: Billie-Jo
authors.initials: BJ
authors.lastname: Hardy
authors.forename: Béatrice
authors.initials: B
authors.lastname: Séguin
authors.forename: Peter A
authors.initials: PA
authors.lastname: Singer
authors.forename: Mitali
authors.initials: M
authors.lastname: Mukerji
authors.forename: Samir K
authors.initials: SK
authors.lastname: Brahmachari
authors.forename: Abdallah S
authors.initials: AS
authors.lastname: Daar
mesh_terms: D001364:Awareness; D014644:Genetic Variation; D015894:Genome, Human; D006801:Humans; D007194:India / Q000453:epidemiology; D009936:Organizational Innovation; D011057:Politics; D017149:Private Sector; D017150:Public Sector