title: Sister Mary Joseph's nodule: Three case reports.
abstract: BACKGROUND
  An umbilical metastatic lesion is called 'Sister Mary Joseph's nodule'. It is an uncommon clinical or radiographic finding, and it is rare as the first sign of a malignant disease.
  
  
  METHODS
  We report three cases of Sister Mary Joseph's nodule. In the three cases presented, the primary tumor was an adenocarcinona of the sigmoid colon, a carcinoma of the bladder, and an adenocarcinoma of the gallbladder, respectively.
  
  
  CONCLUSIONS
  The differential diagnosis of an umbilical lesion should always include metastatic disease apart from benign lesions and primary neoplasms.
authors.affiliation: 1st Department of Propaedeutic Surgery, Hippokrateion General Hospital, Athens Medical School, University of Athens, Q, Sofias 114 av,, 11527, Athens, Greece. alarentz@med.uoa.gr.
authors.forename: Andreas
authors.initials: A
authors.lastname: Larentzakis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Theodorou
authors.forename: Klio
authors.initials: K
authors.lastname: Fili
authors.forename: Anna
authors.initials: A
authors.lastname: Manataki
authors.forename: Vasiliki
authors.initials: V
authors.lastname: Bizimi
authors.forename: Michael
authors.initials: M
authors.lastname: Tibishrani
authors.forename: Stylianos
authors.initials: S
authors.lastname: Katsaragakis