[Microvascular decompression for cranial nerve hyperactive dysfunction].
OBJECTIVE
To assess the results of microvascular decompression (MVD) in treating cranial nerve hyperactive dysfunction.


METHODS
From October 2002 to January 2007, 106 patients with cranial never hyperactive dysfunction were treated with MVD. Among them, there were 47 males and 59 females with an average age of 62 years (42-85 years), including 56 cases of trigeminal neuralgia, 33 cases of hemifacial spasm and 17 cases of spasmodic torticollis. MRI showed obvious nerve root compression in 60 patients (56.6%), suspected nerve root compression in 33 patients (31.1%) and no nerve root compression in 13 patients (12.3%). The disease course was 2-300 months with median course of 54 months. The typical manifestations before operation were pain and myospasm in corresponding innervation region.


RESULTS
The superior cerebellar artery was the most common offending vessel in trigeminal neuralgia (44.6%, 25/56), the anterior inferior cerebellar artery in hemifacial spasm (33.3%, 11/33), and the vertebra-basilar artery in spasmodic torticolis (82.4%, 14/17). Complications of facial paralysis, hypoacusia, facial numbness, dizziness, pain of neck and shoulder, muscles weakness of neck and subcutaneous dropsy occurred in 31 patients (29.2%). All patients were followed up for 6-42 months. The total response rate was 90.6%. The curative rate of MVD was 83.9% (47/56) in trigeminal neuralgia, 81.8% (27/33) in hemifacial spasm and 41.2% (7/17) in spasmodic torticolis, respectively. Five patients failed to response (4.7%), 2 of them were cured after re-operation and 3 abandoned further treatment. Five patients suffered recurrence 3-8 months after operation (4.7%), 2 of them recovered after re-operation, 1 got relief by Gamma-knife treatment, and 2 abandoned further treatment.


CONCLUSIONS
MVD has a good therapeutic effect on the disease caused by vascular compression of cranial nerve. Comprehensive preoperative evaluation, skillful operational technique and intraoperative electrophysiological monitoring should be implemented to enhance the therapeutic effects of MVD and to prevent possible complications.
Yin
Hao
H
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R. China. yinhao168@126.com
Lei
Ting
T
You
Chao
C
Ding
Hao
H
Li
Qiang
Q
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019299:Decompression, Surgical; D005260:Female; D019569:Hemifacial Spasm / Q000601:surgery; D006801:Humans; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D014103:Torticollis / Q000601:surgery; D014277:Trigeminal Neuralgia / Q000601:surgery; D014656:Vascular Surgical Procedures / Q000379:methods