title: Overview of lung transplantation.
abstract: Although significant gains have been made in improving lung function and survival in cystic fibrosis (CF), ultimately respiratory failure is the leading cause of mortality in these patients. For CF patients with end stage lung disease, lung transplantation is an option for treatment. The field of lung transplantation has progressed markedly in the last 20 years. Nonetheless it remains a technically complex and challenging procedure, and patients are at risk for numerous short term and long term complications. Potential transplant recipients must be physically and psychologically prepared for the arduous process involved in lung transplantation. This article will review the history of lung transplantation, indications for transplantation, surgical techniques, and complications of transplantation.
authors.affiliation: Division of Pediatric Pulmonology, Childrens Hospital Los Angeles, 4650 Sunset Boulevard; MS #83, Los Angeles, CA 90027, USA. mwoo@chla.usc.edu
authors.forename: Marlyn S
authors.initials: MS
authors.lastname: Woo
mesh_terms: D001989:Bronchiolitis Obliterans / Q000209:etiology; D003550:Cystic Fibrosis / Q000150:complications / Q000401:mortality / Q000628:therapy*; D006084:Graft Rejection / Q000473:pathology / Q000517:prevention & control*; D016041:Heart-Lung Transplantation; D006801:Humans; D016040:Lung Transplantation / Q000379:methods* / Q000639:trends; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D016559:Tacrolimus / Q000008:administration & dosage; D014019:Tissue Donors
chemical_list: D016559:Tacrolimus