title: Sesquiterpene Glucosides from Chloranthus japonicus Sieb.
abstract: A new lindenane sesquiterpene glucoside named yinxiancaoside A (1), a new, rare bidesmosidic megastigmane sesquiterpene glucoside named yinxiancaoside B (5), and three known sesquiterpene glucosides, chloranoside A (2), pisumionoside (3), and sarcaglaboside A (4), were isolated from the whole plant of Chloranthus japonicus Sieb. The structures of the new compounds were established by an extensive study of their spectral data, especially 1D- and 2D-NMR. The cytotoxic activity of the isolated compounds against human hepatoma (Hepg-2), human ovarian carcinoma (OV420), and human breast cancer (MCF-7) cells was investigated.
authors.affiliation: Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin 150040, P. R. China. hxkuang@hotmail.com
authors.forename: Haixue
authors.initials: H
authors.lastname: Kuang
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Xia
authors.forename: Bingyou
authors.initials: B
authors.lastname: Yang
authors.forename: Qiuhong
authors.initials: Q
authors.lastname: Wang
authors.forename: Shaowa
authors.initials: S
authors.lastname: Lü
mesh_terms: D002470:Cell Survival / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D006027:Glycosides; D012717:Sesquiterpenes