title: Thoracic spinal cord compression by intramedullary hamartomatous tissue in a young boy: case report.
abstract: OBJECTIVE
  Spinal cord hamartomas are a rare occurrence characterized by well- differentiated mature elements located in an irregular position in the spinal cord.
  
  
  METHODS
  The authors present the unique case of a 12-year-old boy who originally presented to our center for treatment of a right thalamic astrocytoma. One year after his initial presentation, the child developed progressive bilateral leg weakness with decreased sensation. Spinal magnetic resonance imaging performed at this time revealed an intramedullary spinal cord lesion from T4 to T8, which was later found to be composed of hamartomatous tissue.
  
  
  METHODS
  The patient underwent bilateral T4 to T8 laminectomies with subtotal resection of the hamartomatous lesion, and his symptoms improved postoperatively.
  
  
  CONCLUSIONS
  Although typically described in the literature as spinal cord hamartomas because of their histological composition, these rare hamartomatous lesions may be the result of a neurulation defect rather than true hamartomas. In patients presenting with multiple neurological conditions, as in our case, diagnosis may be more complex. For those presenting with neurological signs and symptoms, surgical treatment is essential.
authors.affiliation: Department of Neurological Surgery, Children's Hospital and Regional Medical Center, University of Washington School of Medicine, Seattle, Washington, USA. tjabeluw@gmail.com
authors.forename: Taylor J
authors.initials: TJ
authors.lastname: Abel
authors.forename: Abhineet
authors.initials: A
authors.lastname: Chowdhary
authors.forename: George
authors.initials: G
authors.lastname: Jallo
authors.forename: Paul P
authors.initials: PP
authors.lastname: Wang
authors.forename: Peter
authors.initials: P
authors.lastname: Burger
authors.forename: Anthony M
authors.initials: AM
authors.lastname: Avellino
mesh_terms: D002648:Child; D006222:Hamartoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D013117:Spinal Cord Compression / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013904:Thoracic Vertebrae