title: Total syntheses of (+/-)-montanin A and (+/-)-teuscorolide.
abstract: The first total syntheses of (+/-)-montanin A and (+/-)-teuscorolide have been achieved from an advanced precursor previously developed via a Diels-Alder strategy; in the synthetic sequence, the synthesis of montanin A was first accomplished in 8 steps, from which teuscorolide was readily achieved in 2 steps by using a novel furan oxidative cyclization-retro-cyclization process as a key operation.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
authors.forename: I-Chia
authors.initials: IC
authors.lastname: Chen
authors.forename: Yen-Ku
authors.initials: YK
authors.lastname: Wu
authors.forename: Hsing-Jang
authors.initials: HJ
authors.lastname: Liu
authors.forename: Jiang-Liang
authors.initials: JL
authors.lastname: Zhu
mesh_terms: D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D000439:Pentanols / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D005663:Furans; D000439:Pentanols; D013141:Spiro Compounds; C533579:montanin A; C533580:teuscorolide; C015422:2,4-pentadiene-1-ol