Extrahepatic hepatitis C virus after transplantation: diabetes and renal dysfunction.
1. Insulin resistance is associated with hepatitis C virus infection and plays a role in the progression of hepatitis C virus-related liver disease and fibrosis. 2. Treating insulin resistance and achieving glycemic control will be important for improving post-liver transplant morbidity and mortality: control of the hepatitis C virus will help to accomplish this. 3. The main renal complication of hepatitis C virus is membranoproliferative glomerulonephritis, and this occurs most commonly in the setting of mixed cryoglobulinemia.
Sabharwal
Sabina
S
Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Delgado-Borrego
Aymin
A
Chung
Raymond T
RT
D003449:Cryoglobulinemia / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology*; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology*; D006526:Hepatitis C / Q000150:complications* / Q000628:therapy; D006801:Humans; D007333:Insulin Resistance; D017093:Liver Failure / Q000209:etiology; D016031:Liver Transplantation