[Immunohistochemical study of mucins in chronic pancreatitis and ductal adenocarcinoma of the pancreas].
Based on the results of an immunohistological study of MUC1, MUC2, MUC4, MUC5AC, and MUC6 in pancreatic tissue from 50 patients with chronic pancreatitis (CP) and 50 patients with ductal adenocarcinoma (DAC), the authors showed altered mucin immunological responsiveness in severe forms of CP, in the foci of PanIN and DAC. They also revealed that determination of mucin expression may be used in the differential diagnosis of pancreatic cancer.
Paklina
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Setdikova
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism*; D009363:Neoplasm Proteins / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000378:metabolism*; D050500:Pancreatitis, Chronic / Q000175:diagnosis / Q000378:metabolism*; D012189:Retrospective Studies
D009077:Mucins; D009363:Neoplasm Proteins