title: Silent white matter lesion in linear scleroderma en coup de sabre.
abstract: We report a patient with linear scleroderma en coup de sabre without neurological symptoms despite the presence of large white matter lesions. The patient underwent 3.0-T magnetic resonance (MR) examinations including diffusion tensor imaging, time-resolved contrast-enhanced MR angiography, susceptibility-weighted imaging, and proton MR spectroscopy. These imaging findings suggested increased vascular permeability and microbleeding without abnormalities of metabolites. Our observation is consistent with vasculopathy and may be helpful in the proper diagnosis and treatment of linear scleroderma en coup de sabre.
authors.affiliation: Department of Radiology, The Institute of Medical Science, University of Tokyo, Tokyo, Japan. s-mio@umin.ac.jp
authors.forename: Mio
authors.initials: M
authors.lastname: Sakai
authors.forename: Shigeki
authors.initials: S
authors.lastname: Aoki
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Inoue
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Ashida
authors.forename: Haruyasu
authors.initials: H
authors.lastname: Yamada
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kiryu
authors.forename: Sachiko
authors.initials: S
authors.lastname: Inano
authors.forename: Harushi
authors.initials: H
authors.lastname: Mori
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Masutani
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
authors.forename: Hironobu
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000473:pathology*