Management of malaria in children: update 2008.
BACKGROUND
The first guideline on diagnosis and management of malaria in children was formulated by Infectious Diseases Chapter of IAP in 2005. In subsequent year WHO proposed artemisinin based combination therapy in all cases of uncomplicated falciparum malaria. The number of falciparum malaria as well as multidrug resistant falciparum malaria cases are constantly on the rise. So there was need to revise the existing guideline.


METHODS
The first recommendations on the diagnosis and management of malaria in children were formulated in 2005. The same protocol was revised on 12 October 2007 in NIMHANS, Bangalore in the light of various recommendations of WHO, where all the members of the Task Force Committee on Malaria in Children were present.


OBJECTIVE
To revise and update treatment guidelines for malaria with special reference to artemisinin based combination therapy.


CONCLUSIONS
The need for Artemisinin based combination therapy (ACT) is emphasized in chloroquine resistant falciparum malaria. Monotherapy with artesunate will further increase the resistance. Once malaria treatment is initiated it should be completed. In severe malaria the maintenance dose of artesunate is revised.
Department of Pediatrics, Institute of Child Health, Kolkata, India. rkundu22@gmail.com
Kundu
Ritabrata
R
Ganguly
Nupur
N
Ghosh
Tapan Kumar
TK
D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000962:Antimalarials / Q000008:administration & dosage*; D037621:Artemisinins / Q000008:administration & dosage*; D002648:Child; D004334:Drug Administration Schedule; D018432:Drug Resistance, Multiple; D004359:Drug Therapy, Combination; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D016780:Malaria, Vivax / Q000188:drug therapy
D000890:Anti-Infective Agents; D000962:Antimalarials; D037621:Artemisinins