title: A case of cardiogenic shock caused by capecitabine treatment.
abstract: BACKGROUND
  A 52-year-old woman underwent successful resection of stage IIB primary mucinous adenocarcinoma of the appendix and was started on capecitabine chemotherapy. Five days into the first course, after initially experiencing diarrhea, nausea, vomiting and a transient episode of retrosternal chest pain radiating to the left scapula, she presented to the emergency department with cardiogenic shock.
  
  
  METHODS
  Electrocardiography, transthoracic echocardiography, laboratory investigation of cardiac biomarkers, coronary angiography and endomyocardial biopsy.
  
  
  METHODS
  Capecitabine-induced cardiogenic shock.
  
  
  RESULTS
  Supportive treatment with dopamine, milrinone, norepinephrine (noradrenaline) and levosimendan.
authors.affiliation: Green Lane Cardiovascular Service, Auckland City Hospital, Park Road, Grafton, Auckland 1023, New Zealand. andrewcyto@gmail.com
authors.forename: Andrew C Y
authors.initials: AC
authors.lastname: To
authors.forename: Khang Li
authors.initials: KL
authors.lastname: Looi
authors.forename: Dragan
authors.initials: D
authors.lastname: Damianovich
authors.forename: Graeme B
authors.initials: GB
authors.lastname: Taylor
authors.forename: David
authors.initials: D
authors.lastname: Sidebotham
authors.forename: Harvey D
authors.initials: HD
authors.lastname: White
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000188:drug therapy* / Q000601:surgery; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001063:Appendiceal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D000069287:Capecitabine; D002316:Cardiotonic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D017023:Coronary Angiography; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008875:Middle Aged; D012770:Shock, Cardiogenic / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D015415:Biomarkers; D002316:Cardiotonic Agents; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil