title: [Extrahepatic cholestasis secondary to Castleman's disease].
abstract: Castleman's disease is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A 76-year-old man presented with pruritus and jaundice, a cholestasis and an increase of acute phase reactants. Peroperative investigations evidenced a 3-cm lymphadenopathy that compressed the biliary duct. Diagnosis of multicentric Castleman's disease was confirmed by the histologic examination of the lymphadenopathy. HIV testing was negative. Corticosteroid therapy was started and partially controlled the disease.
authors.affiliation: Service de chirurgie générale, hôpital Habib-Bourguiba, Sfax 3003, Tunisie. affesnejm@yahoo.fr
authors.forename: N
authors.initials: N
authors.lastname: Affes
authors.forename: A
authors.initials: A
authors.lastname: Mseddi
authors.forename: N
authors.initials: N
authors.lastname: Feriani
authors.forename: M I
authors.initials: MI
authors.lastname: Beyrouti
mesh_terms: D000368:Aged; D001652:Bile Ducts / Q000601:surgery; D005871:Castleman Disease / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D001651:Cholestasis, Extrahepatic / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007565:Jaundice / Q000209:etiology; D008297:Male; D011537:Pruritus / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids