title: Long-term storable and shippable lipid bilayer membrane platform.
abstract: The fragility and short lifetimes characteristic of conventionally formed lipid bilayer membranes has necessitated their preparation to be at the time and point of use. By using high freezing-point lipid-solvent mixtures, the process of lipid bilayer self-assembly may be reversibly arrested. In solid form, the bilayer precursor can be stored indefinitely and is sufficiently robust to withstand commercial shipping. Upon thawing, bilayer self-assembly resumes, resulting in a biologically functional membrane. Combination of this membrane precursor with an inexpensive chip results in a compact, practical, and disposable platform for ion channel measurements.
authors.affiliation: University of California, Los Angeles, Department of Bioengineering, Los Angeles, CA 90095, USA.
authors.forename: Tae-Joon
authors.initials: TJ
authors.lastname: Jeon
authors.forename: Jason L
authors.initials: JL
authors.lastname: Poulos
authors.forename: Jacob J
authors.initials: JJ
authors.lastname: Schmidt
mesh_terms: D005615:Freezing; D008051:Lipid Bilayers
chemical_list: D008051:Lipid Bilayers