Dapsone-induced photosensitivity: a rare clinical presentation.
Dapsone is an efficient anti-inflammatory and antimycobacterial agent. It is one of the main constituents of multidrug therapy (MDT). It acts by interference with folate metabolism. Dapsone-induced photosensitivity is a rare, non-dose-related adverse effect of the sulfone and can occur in patients with inflammatory skin disorders treated with dapsone. So far, only 12 cases seem to have been reported in the literature. We report a case of dapsone-induced photosensitivity in an Indian patient with leprosy.
Kar
Bikash Ranjan
BR
Department of Dermatology, Institute of Medical Sciences & SUM Hospital, Orissa, India. karbikash@yahoo.com
D000328:Adult; D003622:Dapsone / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007194:India; D007917:Leprostatic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015440:Leprosy, Lepromatous / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology
D007917:Leprostatic Agents; D003622:Dapsone