Metal-catalyzed reaction of N-(2-indolyl)methyl, N-bis(trimethylsilyl)methyl diazoamides: an entry into the beta-carboline ring system.
The intramolecular metal-catalyzed reaction of N-(2-indolyl)methyl, N-bis(TMS)methyl diazoamides proceeds with high conformational control and chemoselectivity to give cyclopropyl derivatives, which rearrange to beta-carboline products.
Zhang
Bao
B
Department of Chemistry and Biochemistry, University of Regina, Regina, Saskatchewan, S4S 0A2, Canada.
Wee
Andrew G H
AG
D001391:Azo Compounds / Q000737:chemistry*; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D007211:Indoles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D001391:Azo Compounds; D002243:Carbolines; D007211:Indoles; D012238:Rhodium