title: [Investigations on the antioxidative metabolism during the periparturient period in dairy goats with special regard to seasonal differences in feeding and management].
abstract: In a herd of 1400 dairy goats with an average milk yield of 840 kg/year, 40 "Weisse Deutsche Edelziegen" (October-January: n = 19; April-July: n = 21) were examined. Venous blood samples were collected 6-8, 3-4 and < 2 weeks (wks) ante partum (a. p.) and 2-4 days (d), 3-4 and 6-8 wks post partum (p. p.). Antioxidative Capacity of Water soluble substances (ACW) and Trolox Equivalent Antioxidative Capacity (TEAC) were measured in serum; activities of superoxide dismutase (SOD) and glutathione peroxidase (GPX) were measured in an erythrocyte pellet and in whole blood. ACW and TEAC increased significantly 3-4 wks p. p. In summer these two parameters showed significantly higher concentrations than in winter. The SOD had a significantly higher activitiy < 2 wks a. p. and 6-8 wks p. p. GPX-activity showed a constant increase from the beginning of investigations and from 3-4 wks p. p. up to the end of investigations activities were significantly higher than 6-8 wks a. p. The samples ante partum and the first sample taken post partum showed significantly higher activities in summer than in winter. The present study shows, that the metabolic challenge associated to the periparturient period in combination with changing capacity of food intake, influences the antioxidative metabolism in dairy goats. Seasonal depending changes on feeding quality and climate (barn temperature, quality of feeding components) also influence this system.
authors.affiliation: Medizinische Tierklinik der Veterinärmedizinischen Fakultät, Universität Leipzig. locher@vetmed.uni-leipzig.de
authors.forename: Lena
authors.initials: L
authors.lastname: Locher
authors.forename: Anett
authors.initials: A
authors.lastname: Rudovsky
authors.forename: Manfred
authors.initials: M
authors.lastname: Fürll
mesh_terms: D000821:Animal Feed; D000822:Animal Husbandry; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D003612:Dairying / Q000379:methods*; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D006041:Goats / Q000097:blood / Q000378:metabolism*; D010084:Oxidation-Reduction; D049590:Postpartum Period / Q000097:blood / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood / Q000378:metabolism*; D012621:Seasons; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors
chemical_list: D000975:Antioxidants; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase