Bioactive apocarotenoids from Tectona grandis.
The bioactive fractions of Tectona grandis have yielded seven apocarotenoids, two of which have been isolated for the first time as natural products (tectoionols A and B). The chemical structures were determined through 1D and 2D nuclear magnetic resonance experiments. The absolute configuration of tectoionol A was determined using a modified Mosher methodology. Some NMR assignments for the compounds 9(S)-4-oxo-7,8-dihydro-beta-ionol and 3beta-hydroxy-7,8-dihydro-beta-ionone have been corrected on the basis of g-HSQC and g-HMBC experiments. The general bioactivities of isolated compounds have been studied using etiolated wheat coleoptiles. Those compounds that presented higher levels of activity were assayed on standard target species (Lactuca sativa, Lycopersicum esculentum, Lepidium sativum and Allium cepa).
Macías
Francisco A
FA
Grupo de Alelopatía, Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, C/ República Saharaui s/n, Apdo. 40, 11510-Puerto Real (Cádiz), Spain. famacias@uca.es
Lacret
Rodney
R
Varela
Rosa M
RM
Nogueiras
Clara
C
Molinillo
Jose M G
JM
D001681:Biological Assay; D001688:Biological Products / Q000302:isolation & purification / Q000494:pharmacology; D002212:Capsicum / Q000187:drug effects / Q000254:growth & development; D002338:Carotenoids / Q000302:isolation & purification* / Q000494:pharmacology*; D019686:Lamiaceae / Q000737:chemistry*; D018551:Solanum lycopersicum / Q000187:drug effects / Q000254:growth & development; D032323:Solanum melongena / Q000187:drug effects / Q000254:growth & development; D014908:Triticum / Q000187:drug effects / Q000254:growth & development
D001688:Biological Products; D002338:Carotenoids