Contact dermatitis associated with food: retrospective cross-sectional analysis of North American Contact Dermatitis Group data, 2001-2004.
BACKGROUND
Allergic and irritant contact dermatitis to food is likely underreported.


OBJECTIVE
To characterize relevant allergens and irritants associated with food in patients referred to the North American Contact Dermatitis Group (NACDG) for patch testing.


METHODS
Retrospective analysis of cross-sectional data from the NACDG from 2001 to 2004.


RESULTS
Of 10,061 patch-tested patients, 109 (1.1%) had a total of 122 reactions associated with food. Approximately two-thirds of patients (66%) were female, and one-third (36%) were atopic. The hands were the most common sites of dermatitis (36.7%). There were 78 currently relevant (definite, probable, or possible) allergic reactions to NACDG standard series allergens with a food source; the most common allergen was nickel (48.7%), followed by Myroxilon pereirae (balsam of Peru) (20.6%) and propylene glycol (6.4%). Twenty allergic reactions to non-NACDG standard allergens and 24 relevant food irritants were also identified. Overall, 21% (25 of 122) of all reactions (irritant and allergic) were occupation related; the majority of these (17 of 25) were relevant irritant reactions. Cooks were the most commonly affected occupational group (40%).


CONCLUSIONS
In this limited data set, nickel, Myroxilon pereirae, and propylene glycol were the most common allergens identified with a food source. Of food-related occupational disease, irritation was more common than allergy.
Warshaw
Erin M
EM
Veterans Affairs Medical Center, Minneapolis, MN, USA.
Botto
Nina C
NC
Zug
Kathryn A
KA
Belsito
Donald V
DV
Maibach
Howard I
HI
Sasseville
Denis
D
Fowler
Joseph F
JF
Storrs
Frances J
FJ
Taylor
James S
JS
DeLeo
Vincent A
VA
Marks
James G
JG
Mathias
C G Toby
CG
Pratt
Melanie D
MD
Rietschel
Robert L
RL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens; D002648:Child; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D017453:Dermatitis, Irritant / Q000175:diagnosis / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005502:Food / Q000009:adverse effects*; D005504:Food Analysis; D005511:Food Handling; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D055815:Young Adult
D000485:Allergens