[Advancement of targeting therapy for retinal neovascularization].
Retinal angiogenesis could be attributed to complex interactions among multiple angiogenic stimulators. Under pathological condition, angiogenic molecules, such as metalloproteinase, erythropoietin, integrin, promote retinal neovascularization through different pathway. Therapy target to these molecules involving in retinal angiogenesis could suppress retinal neovascularization effectively. This article reviews recent progress in studies on the molecules participating in retinal angiogenesis and therapy targeting it.
Xiong
Si-qi
SQ
Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China.
Xia
Xiao-bo
XB
D006801:Humans; D015861:Retinal Neovascularization / Q000628:therapy*