Role of negative pressure wound therapy in treating peripheral vascular graft infections.
Wound complications involving large subcutaneous vessels can cause significant challenges for surgeons. Negative pressure wound therapy (NPWT) has been increasingly used for treating complex wounds in vascular surgery, including groin infections, either as a bridge to surgical closure or as a primary wound treatment modality. Although a growing body of evidence exists for managing various problematic wounds, such as diabetic foot ulcers and open abdominal wounds, the role of NPWT in wounds involving large blood vessels or wounds complicating infected vascular grafts has not been well defined. A multidisciplinary advisory panel reviewed the literature relevant to wounds related to vascular surgical procedures and complications, focusing on large subcutaneous or infected vascular conduits. The results supported by the literature and the clinical practice of the consensus panel suggested that NPWT can be a useful adjunct to the management of vascular groin infections and dehiscences but must be used with caution.
Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA. bauer.sumpio@yale.edu
Bauer E
BE
Sumpio
David E
DE
Allie
Keith A
KA
Horvath
William A
WA
Marston
Herbert L
HL
Meites
Joseph L R
JL
Mills
Dennis P
DP
Orgill
Jorge D
JD
Salazar
David H
DH
Song
Boulos
B
Toursarkissian
D000287:Administration, Topical; D000890:Anti-Infective Agents / Q000008:administration & dosage; D017719:Diabetic Foot / Q000150:complications / Q000628:therapy; D005260:Female; D006119:Groin / Q000098:blood supply / Q000601:surgery; D006801:Humans; D008297:Male; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D009779:Occlusive Dressings; D016491:Peripheral Vascular Diseases / Q000601:surgery*; D017410:Practice Guidelines as Topic; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000628:therapy; D013524:Surgical Flaps / Q000098:blood supply* / Q000382:microbiology; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000517:prevention & control*; D014656:Vascular Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D014945:Wound Healing / Q000502:physiology
D000890:Anti-Infective Agents