[Advancement of targeting therapy for retinal neovascularization].
Retinal angiogenesis could be attributed to complex interactions among multiple angiogenic stimulators. Under pathological condition, angiogenic molecules, such as metalloproteinase, erythropoietin, integrin, promote retinal neovascularization through different pathway. Therapy target to these molecules involving in retinal angiogenesis could suppress retinal neovascularization effectively. This article reviews recent progress in studies on the molecules participating in retinal angiogenesis and therapy targeting it.
Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China.
Si-qi
SQ
Xiong
Xiao-bo
XB
Xia
D006801:Humans; D015861:Retinal Neovascularization / Q000628:therapy*