Simplex-optimized chromatographic resolution of selected ionic liquid cations utilizing a polar reversed-phase system.
This study reports on optimization of the RP-HPLC separation of imidazolium and pyridinium ionic liquid cations using a variable-size simplex algorithm. Under the optimized conditions, all critical pairs of ionic liquids were successfully separated in a single chromatographic run. The mobile phase at the point corresponding to the optimum consisted of 10% MeOH and 90% 15 mM KH(2)PO(4)/H(3)PO(4) with pH 3.43. The coefficients of asymmetry for all of the compounds analyzed at the simplex algorithm optimum ranged from 0.83 to 2.91.
Nichthauser
Joanna
J
Department of Environmental Analysis, Faculty of Chemistry, University of Gdańsk, Poland.
Paszkiewicz
Monika
M
Składanowski
Andrzej C
AC
Stepnowski
Piotr
P
D000465:Algorithms; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007093:Imidazoles / Q000302:isolation & purification; D052578:Ionic Liquids / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000302:isolation & purification
D007093:Imidazoles; D052578:Ionic Liquids; D011726:Pyridinium Compounds; C029899:imidazole