Complete 1H and 13C NMR spectral assignment of benzo[d]isothiazole derivatives and of an isoindole isoster.
The complete (1)H and (13)C NMR assignments of the novel compound methyl 2-amino-3-(benzo[d]isothiazol-3-yl)propanoate (1), of 3-amino-5-methylbenzo[d]isothiazole (2) and N-(t-butyloxycarbonyl)-2-aminobenzo[d]isothiazol-3(2H)-one (3) and of the desulfurated isostere of 3, N-(t-butyloxycarbonyl)-2-aminoisoindolin-1-one (4), using 1D and 2D NMR techniques, including COSY, INADEQUATE, HSQC, and HMBC experiments are reported.
Dipartimento Farmaceutico, Università degli Studi di Parma, Viale G. P. Usberti 27/A, Parma 43100, Italy. matteo.incerti@unipr.it
Matteo
M
Incerti
Domenico
D
Acquotti
Paola
P
Vicini
D052160:Benzothiazoles / Q000737:chemistry*; D002247:Carbon Isotopes; D054833:Isoindoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D052160:Benzothiazoles; D002247:Carbon Isotopes; D054833:Isoindoles; C005465:benzothiazole