Biological control of aflatoxin contamination of crops.
Aflatoxins produced primarily by two closely related fungi, Aspergillus flavus and Aspergillus parasiticus, are mutagenic and carcinogenic in animals and humans. Of many approaches investigated to manage aflatoxin contamination, biological control method has shown great promise. Numerous organisms, including bacteria, yeasts and nontoxigenic fungal strains of A. flavus and A. parasiticus, have been tested for their ability in controlling aflatoxin contamination. Great successes in reducing aflatoxin contamination have been achieved by application of nontoxigenic strains of A. flavus and A. parasiticus in fields of cotton, peanut, maize and pistachio. The nontoxigenic strains applied to soil occupy the same niches as the natural occurring toxigenic strains. They, therefore, are capable of competing and displacing toxigenic strains. In this paper, we review recent development in biological control of aflatoxin contamination.
Yin
Yan-Ni
YN
Institute of Biotechnology, Zhejiang University, Hangzhou 310029, China.
Yan
Lei-Yan
LY
Jiang
Jin-Hua
JH
Ma
Zhong-Hua
ZH
D000348:Aflatoxins / Q000096:biosynthesis / Q000633:toxicity*; D000818:Animals; D001230:Aspergillus / Q000254:growth & development / Q000472:pathogenicity / Q000502:physiology; D001231:Aspergillus flavus / Q000254:growth & development / Q000472:pathogenicity / Q000502:physiology; D005506:Food Contamination / Q000517:prevention & control*; D006540:Herbicides; D006801:Humans; D010572:Pest Control, Biological / Q000379:methods*; D012988:Soil Microbiology; D013045:Species Specificity
D000348:Aflatoxins; D006540:Herbicides