Structure elucidation and NMR assignments for two amide alkaloids from a Mangrove endophytic Fungus (No. ZZF-22).
The structure elucidations and complete (1)H and (13)C NMR assignments are reported for two new natural products: 3-benzylidene-8,8a-dihydroxy-2-methyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione(1) and 4-hydroxy-6-(hydroxy-phenyl-methyl)-N-(3-methyl-butyryl)-nicotinamide (2). Both of these secondary metabolites were isolated from the fermentation medium of a Mangrove endophytic fungus. High resolution electron impact mass spectrometry (HREIMS), FT-IR Spectroscopy and NMR experiments including gCOSY, gHMQC, gHMBC and NOE were used for determination of the structures and assignments of the amide alkaloids.
Chen
Yiguang
Y
School of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, Guangzhou, 510275, PR China.
Shao
Changlun
C
Huang
Zhongjing
Z
Zhang
Ying
Y
Cai
Xiaoling
X
She
Zhigang
Z
Zhou
Shining
S
Lin
Yongcheng
Y
D000470:Alkaloids / Q000737:chemistry*; D000577:Amides / Q000737:chemistry; D001688:Biological Products / Q000737:chemistry; D002247:Carbon Isotopes; D005658:Fungi / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D019684:Magnoliopsida / Q000382:microbiology; D013058:Mass Spectrometry; D015394:Molecular Structure; D043982:Rhizophoraceae / Q000382:microbiology; D017550:Spectroscopy, Fourier Transform Infrared
D000470:Alkaloids; D000577:Amides; D001688:Biological Products; D002247:Carbon Isotopes