Etanercept-induced lupus erythematosus presenting as a unilateral pleural effusion.
A 72-year-old man receiving etanercept for the treatment of psoriatic arthritis had an exudative pleural effusion with nonspecific fluid analysis and pleural biopsy findings. He was ultimately found to have drug-induced lupus erythematosus due to the etanercept. The spectrum of autoimmune disease due to the use of tumor necrosis factor inhibitors is reviewed.
Abunasser
Jafar
J
Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT.
Forouhar
Faripour A
FA
Department of Anatomic Pathology and Laboratory Medicine, University of Connecticut School of Medicine, Farmington, CT.
Metersky
Mark L
ML
Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT. Electronic address: Metersky@nso.uchc.edu.
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D010996:Pleural Effusion / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D018124:Receptors, Tumor Necrosis Factor
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept