Profile Comparer: a program for scoring and aligning profile hidden Markov models.
Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief description of the profile-profile algorithm used by PRC.


BACKGROUND
The C source code licensed under the GNU General Public Licence and Linux and Mac OS X binaries can be downloaded from http://supfam.org/PRC.


BACKGROUND
Supplementary data are available at Bioinformatics online.
Madera
Martin
M
Department of Computer Science, University of Bristol, Bristol, UK. martin.madera@gmail.com
D000465:Algorithms; D019295:Computational Biology; D008390:Markov Chains; D008954:Models, Biological; D012984:Software