Human embryonic stem cell differentiation toward regional specific neural precursors.
Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration.
Centro de Investigación Príncipe Felipe, Valencia, Spain.
Slaven
S
Erceg
Mohammad
M
Ronaghi
Miodrag
M
Stojković
D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology*; D006801:Humans; D009474:Neurons / Q000166:cytology*; D009836:Oligodendroglia / Q000166:cytology; D009928:Organ Specificity