Decline in the risk of hepatitis A virus infection in China, a country with booming economy and changing lifestyles.
The objective of the study was to identify the protective factors for the rapid decline in the risk of hepatitis A virus (HAV) infection in China between 1990 and 2006. Results of serological follow-up and data on annual hepatitis A incidence were analysed and correlated with economic growth and HAV vaccine output during the same period. In conclusion, both HAV vaccination and changing lifestyles associated with the booming economy contributed to the rapid risk decline. Changing lifestyles played a major role in the decline especially in the areas with booming economy.
Xu
Zhi-Yu
ZY
International Vaccine Institute, Seoul, Korea. xuzhiyi@ivi.int
Wang
Xuan-Yi
XY
Liu
Chang-Qing
CQ
Li
Yang-Ting
YT
Zhuang
Fang-Chen
FC
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004405:Dysentery, Bacillary / Q000453:epidemiology; D006506:Hepatitis A / Q000191:economics / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D022362:Hepatitis A Vaccines / Q000276:immunology; D030041:Hepatitis A virus; D006801:Humans; D015994:Incidence; D007223:Infant; D008019:Life Style; D012307:Risk Factors; D012424:Rural Population; D055815:Young Adult
D022362:Hepatitis A Vaccines