[A case of uterine carcinosarcoma].
Uterine carcinosarcoma is a highly aggressive neoplasm with tendency to early recurrence and/or metastasis. The neoplasia has both epithelial and stromal malignant components. Clinically, it is characterized by a postmenopausal metrorrhagia, associated sometimes with abdominal pain. The Authors describe a case of carcinosarcoma in a 82-year old woman with a vaginal bleeding since 10 months and an ingravescent hypochromic anemia. The RMN of the abdomen and pelvis showed a mass occupying the whole uterine lumen, without signs of pelvic diffusion. A bilateral hystero-oophorectomy was performed; the patient's critical conditions and a high anaesthesiological risk advised us not to perform a bilateral pelvic lymphadenectomy with aortic sampling. Six months after operation, a clinical follow-up with a total-body CT didn't show any sign of local recurrence and/or distant metastasis. From the analysis of this case report and from the data of the literature some important considerations can be done: a) gynecologic check up in post-menopausal women with associated risk factors (obesity and hypertension) can allow an early diagnosis also in asymptomatic patients; b) sovrapubic and transvaginal US, abdomino-pelvic CT and MRI are essential for a correct clinical staging; c) surgical excision followed by the histological examination of the specimen is mandatory to establish a correct diagnosis.
Spaziani
E
E
Università degli Studi di Roma La Sapienza, I Facoltà di Medicina e Chirurgia, Polo Pontino, Ospedale A. Fiorino, Terracina (LT), U.O.C. di Chirurgia Generale Universitaria.
Picchio
M
M
Di Filippo
A
A
Petrozza
V
V
Censi
F
F
Sardella
B
B
Briganti
M
M
Ceci
F
F
Nicodemi
S
S
Nardecchia
G
G
De Angelis
F
F
Cipriani
B
B
Stagnitti
F
F
D000369:Aged, 80 and over; D002296:Carcinosarcoma / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000601:surgery
Carcinosarcoma dell'utero: descrizione di un caso clinico.