[Roller compaction research of Banlangen effervsce tablets].
OBJECTIVE
To study the conditions and parameters of roller compaction of Banlangen effervsce tablet.


METHODS
The experimentation adopts L9 (3(4)) orthogonal experiment to study the conditions and parameters of roller compaction of Banlangen effervsce tablet; studied factors that included roller pressure, roller speed and moisture content of power, which influence the result of granule yield and granule friability.


RESULTS
The optimal technique is: roller pressure at 1.5 MPa; roller speed at 15 Hz; moisture content of power at 1.5%.


CONCLUSIONS
The study of roller compaction technique of Banlangen effervsce tablets provides some technicial consults of its research and production.
National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Nanchang 330006, China. luoxj98@126.com
Xiao-jian
XJ
Luo
Hong-liang
HL
Xin
Xiao-yong
XY
Rao
Zhi-qiang
ZQ
Xiao
Li-li
LL
Gao
Ting-ting
TT
Sun
Xin-rui
XR
Li
D000704:Analysis of Variance; D004339:Drug Compounding / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D011312:Pressure; D013607:Tablets; D013997:Time Factors; D014867:Water / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D013607:Tablets; D014867:Water; C540579:banlangen