Retroperitoneal malignant solitary fibrous tumor of the small pelvis causing recurrent hypoglycemia by secretion of insulin-like growth factor 2.
A 28-yr-old man presented with recurrent reduced consciousness, generalized seizures of unknown etiology, recurrent hypoglycemia, psychomotor retardation, and grade 2 ectasia of the left kidney. Abdominal computed tomography (CT) and positron emission tomography (PET) scans demonstrated a well-circumscribed suprapubic pelvic mass, measuring 18 x 15 x 11 cm, with involvement of para-aortic lymph nodes and dilatation of the left ureter suggestive of an extragonadal testicular tumor. We excised the tumor by laparotomy, and it was confirmed to be a solitary fibrous tumor (SFT). After surgery and R0 tumor resection, the patient had no further evidence of hypoglycemia or of recurrence.
Department of Urology and Kidney Transplantation, Martin Luther University, Ernst Grube Str. 40, 06120 Halle, Saale, Germany. sigrid.wagner@medizin.uni-halle.de
Sigrid
S
Wagner
Francesco
F
Greco
Amir
A
Hamza
Rashid M
RM
Hoda
Hans Jürgen
HJ
Holzhausen
Paolo
P
Fornara
D000328:Adult; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism*; D008297:Male; D012008:Recurrence; D012186:Retroperitoneal Neoplasms / Q000150:complications* / Q000378:metabolism*; D054364:Solitary Fibrous Tumors / Q000150:complications* / Q000378:metabolism*
D007335:Insulin-Like Growth Factor II