Current concepts for management of soft tissue sarcomas of the extremities.
Wide resection and limb-salvage surgery remain the gold standard for the management of patients with soft tissue sarcomas of the extremities. Innovations in understanding tumor biology and limb-salvage techniques have led amputation rates to decline. Radiation therapy and novel chemotherapy agents and dosing regimens are supplementing oncology-related surgical treatment. A multidisciplinary team approach with input from oncologists, pathologists, radiation oncologists, and orthopaedic and plastic surgeons is necessary for the management of patients with soft tissue sarcomas of the extremities.
First Department of Orthopaedics, ATTIKON University Hospital, University of Athens, School of Medicine, Athens, Greece. pjp@hol.gr
Panayiotis J
PJ
Papagelopoulos
Andreas F
AF
Mavrogenis
Dimitrios P
DP
Mastorakos
Pavlos
P
Patapis
Panayotis N
PN
Soucacos
D000671:Amputation, Surgical; D001918:Brachytherapy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005121:Extremities; D006801:Humans; D007432:Intraoperative Period; D023821:Limb Salvage; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local; D010348:Patient Care Team; D011879:Radiotherapy Dosage; D019651:Plastic Surgery Procedures; D012509:Sarcoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*