[Endoscopic placement of a "plug" made of acellular biomaterial: a new technique for the repair of gastric leak after Roux-en-Y gastric bypass].
BACKGROUND
Roux-en-Y gastric bypass is one of the most commonly performed bariatric surgeries in Brazil. Gastric leaks are relatively uncommon and potentially dangerous complications. The initial management of gastric leaks consists in adequate drainage, nutritional support, antibiotics and acid suppression. In almost 30% of the cases the fistula will become chronic.


OBJECTIVE
A novel peroral endoscopic treatment of gastric leaks in Roux-en-Y gastric bypassed patients is presented.


METHODS
An acellular biomaterial was endoscopically placed in the fistulous orifice in order to promote healing and avoid surgery in 25 patients. The time between fistula diagnosis and endoscopic treatment varied from 4 to 25 weeks (median: 7 weeks).


RESULTS
Endoscopic treatment was successful in 20 (80%) patients. Fistula closure was obtained after one, two and three sessions in 6 (30%), 11 (55%) and 3 (15%) patients, respectively. No procedure related complications were observed.


CONCLUSIONS
Endoscopic repair of gastric leak after Roux-en-Y gastric bypass by using an acellular biomaterial is safe and effective. However two or three endoscopic sessions are usually needed.
Maluf-Filho
Fauze
F
Serviço de Endoscopia Gastrointestinal, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. fauze.maluf@terra.com.br
Lima
Marcelo Simas de
MS
Hondo
Fabio
F
Giordano-Nappi
José Humberto
JH
Garrido
Teresa
T
Sakai
Paulo
P
D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects*; D005747:Gastric Fistula / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D001672:Biocompatible Materials
Experiência inicial no tratamento endoscópico de fístulas gastrocutâneas pós-gastroplastia vertical redutora através da aplicação de matriz acelular fibrogênica.