[Variance of serum prolactin in controlled ovarian stimulation].
OBJECTIVE
To investigate the variance of peripheral blood prolactin (PRL) in controlled ovarian stimulation.


METHODS
Seventy-two patients, with totally 106 cycles receiving a long protocol of gonadotropin-releasing hormone agonist combined with gonadotropin (Gn) were randomly enrolled in this retrospective study. During controlled ovarian stimulation, peripheral blood hormones were measured by chemiluminescent microparticle immunoassay.


RESULTS
Prolactin was positively correlated with estradiol (r = 0.5897, P < 0.01) while there was no significant correlation between luteinizing hormone and PRL Progesterone had a positive relation with prolactin (r = 0.1412, P < 0.01).


CONCLUSIONS
During controlled ovarian stimulation, prolactin secretion is not affected by Gn but may be stimulated by estradiol. Progesterone has a positive relation with prolactin.
Department of Assisted Reproductive Technology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. lxyzy@263.net
Xiao-Yan
XY
Liang
Yong-Lao
YL
Xiong
Guang-Lun
GL
Zhuang
D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D004958:Estradiol / Q000097:blood* / Q000378:metabolism; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage* / Q000819:agonists; D006062:Gonadotropins / Q000008:administration & dosage; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D006080:Ovarian Follicle / Q000187:drug effects / Q000502:physiology; D010062:Ovulation Induction; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood* / Q000378:metabolism; D012189:Retrospective Studies
D006062:Gonadotropins; D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone