Recurrent Kikuchi-Fujimoto disease during pregnancy: report of case evolving into systemic lupus erythematosus and review of published work.
Kikuchi-Fujimoto disease (KFD) is a distinctive, benign type of necrotizing lymphadenitis. KFD is a rare entity, especially during pregnancy. Although first described in Japan, subsequently it has been reported in the West. We communicate herein a case of KFD in African women with bouts during pregnancy. Diagnosis was difficult because peripheral enlarged lymph nodes were absent and an extended differential diagnosis and adequate work-up was necessary. The patient suffered a miscarriage coinciding with a KFD bout. Further pregnancies were uneventful. Follow up showed that KFD evolved into a systemic lupus erythematosus-like syndrome.
Systemic Autoimmune Disease Unit, Service of Internal Medicine I, University Hospital of Vall d'Hebron, Barcelona, Spain. jalijotas@vhebron.net
Jaume
J
Alijotas-Reig
Manel
M
Casellas-Caro
Raquel
R
Ferrer-Oliveras
Lluis
L
Cabero-Roura
Miquel
M
Vilardell-Tarres
D000328:Adult; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000209:etiology; D012008:Recurrence