Complementary angiographic and autofluorescence findings in pseudoxanthoma elasticum.
Pseudoxanthoma elasticum (PXE) is a systemic disease with characteristic findings on fundus examination. The fundus findings may be difficult to detect with ophthalmoscopy. A case report is described as follows. A PXE patient had subtle retinal findings on fundoscopy that were more prominently seen using a combination of both fundus autofluorescence (FAF) imaging and indocyanine green (ICG) angiography. The fundus features visualized using each of these two modalities appeared different from each other. FAF imaging and ICG angiography may be able to more prominently detect pathology at the level of the retinal pigment epithelium and Bruch's membrane, respectively. The use of these imaging modalities together may be complementary and useful in the evaluation of patients with PXE.
Lee
Thomas K M
TK
Department of Ophthalmology, University of Alberta, Alberta, Canada.
Forooghian
Farzin
F
Cukras
Catherine
C
Wong
Wai T
WT
Chew
Emily Y
EY
Meyerle
Catherine B
CB
D000793:Angioid Streaks / Q000209:etiology / Q000473:pathology; D016570:Bruch Membrane / Q000473:pathology; D005451:Fluorescein Angiography; D005453:Fluorescence; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D011561:Pseudoxanthoma Elasticum / Q000150:complications / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology; D014792:Visual Acuity
D007208:Indocyanine Green