QSAR for predicting joint toxicity of halogenated benzenes to Dicrateria zhanjiangensis.
In this study, the toxicity of 49 mixed halogenated benzenes to Dicrateria zhanjiangensis was determined and the partition coefficient of these mixtures was described by using the C(18)-Empore disks/water partition coefficient (K(mix)). According to these data, a simple K(mix)-based QSAR model was successfully used to correlate the toxicity of the mixed halogenated benzenes to D. zhanjiangensis.
Key Laboratory of Tropical Marine Environmental Dynamics, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China. zmrainbow@yahoo.com.cn
Ming
M
Zeng
ZhiFen
Z
Lin
DaQiang
D
Yin
KeDong
K
Yin
D001555:Benzene Derivatives / Q000737:chemistry / Q000633:toxicity*; D056890:Eukaryota / Q000187:drug effects* / Q000254:growth & development; D054879:Halogenation; D008962:Models, Theoretical; D021281:Quantitative Structure-Activity Relationship; D018675:Toxicity Tests
D001555:Benzene Derivatives