Rhabdomyosarcoma masquerading as acute leukemia.
Rhabdomyosarcoma (RMS) masquerading as acute leukemia (AL) is very rare. We describe three cases with RMS without any symptoms of solid tumors. Bone marrow (BM) showed approximately 95% of blast-like abnormal cells, lacking almost all of the surface antigens of myeloid- and lymphoid-lineage. The immunohistochemistry revealed positive of the cells for actin, desmin and myoglobin. It is important to examine BM samples by immunohistochemistry, when a flow cytometric analysis reveals an unusual presentation.
Shinkoda
Yuichi
Y
Section of Pediatrics, National Kyushu Cancer Center, Fukuoka, Japan.
Nagatoshi
Yoshihisa
Y
Fukano
Reiji
R
Nishiyama
Kenichi
K
Okamura
Jun
J
D000208:Acute Disease; D001854:Bone Marrow Cells / Q000473:pathology; D001856:Bone Marrow Examination; D002648:Child; D003937:Diagnosis, Differential; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D007938:Leukemia / Q000175:diagnosis*; D008297:Male; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000473:pathology