Spot urine protein: creatinine ratio versus 24 hour urine protein at various levels of GFR patients referred to a tertiary care hospital of Pakistan.
OBJECTIVE
To determine the correlation of "random single voided urine protein: creatinine ratio" to "twenty four hour urine protein" at different levels of glomerular filtration rate (GFR) in Pakistani population.


METHODS
A total of 107 patients were included in this cross section study. Patients were divided into five groups according to the GFR. Spot urine protein: creatinine ratio and 24 hour urine protein was measured by the standard methods. The correlation coefficient ( r) between the two was calculated in each group separately.


RESULTS
The GFR in groups 1 to 5 was > or =90, 60-89, 30-59, 15-29, and <15 ml/minute/1.73 m2 respectively. In group one correlation coefficient "r" was 0.96, in group two "r" was 0.81, in group three "r" was 0.94, in group four "r" was 0.82 and in group five "r" was 0.80.


CONCLUSIONS
"Random single voided urine protein: creatinine ratio" may be used as an alternative to "24 hour urine collection for protein" at all levels of GFR in Pakistani population.
Aga Khan University Hospital, Pakistan.
Absar
A
Ali
Naila
N
Asif
Sonia
S
Yaqub
Waqar
W
Kashif
Diamond
D
Merchant
Iffat
I
Yazdant
D003404:Creatinine / Q000652:urine*; D003430:Cross-Sectional Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000652:urine*; D013223:Statistics as Topic; D016482:Urinalysis
D003404:Creatinine