Palladium-catalyzed carboxamidation reaction and aldol condensation reaction cascade: a facile approach to ring-fused isoquinolinones.
Palladium-catalyzed carboxamidation reaction and aldol condensation reaction cascade are very useful for the synthesis of various ABC ring substituted fused isoquinolinones.
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
Gagan
G
Chouhan
Howard
H
Alper
D000447:Aldehydes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D005663:Furans / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D000447:Aldehydes; D000577:Amides; D002264:Carboxylic Acids; D005663:Furans; D007546:Isoquinolines; D008698:Mesylates; D010165:Palladium; C116609:3-hydroxybutanal