[Chronic transplant nephropathy].
In 2007 there were important scientific contributions in the field of kidney transplant and specifically in chronic transplant nephropathy (interstitial fibrosis and tubular atrophy). A new nomenclature and classification of chronic kidney disease was probably the most important contribution in this entity. Use of the C4d stain has allowed the concepts of glomerulopathy to be updated and to reveal the frequency of this entity and its impact in kidney transplant. Finally, two experimental studies provide new perspectives on the treatment of chronic kidney disease such as the use of statins or the use of pyridoxamine to block glycation end products.
Servicio de Nefrologia y Transplante Renal, Hospital Clinico, Universidad de Barcelona, Barcelona, Espana.
J M
JM
Campistol Plana
D000818:Animals; D000069059:Atorvastatin; D001284:Atrophy; D001706:Biopsy; D002908:Chronic Disease; D015935:Complement C4b / Q000032:analysis; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation; D007684:Kidney Tubules / Q000737:chemistry / Q000473:pathology* / Q000503:physiopathology; D009395:Nephritis, Interstitial / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control; D010446:Peptide Fragments / Q000032:analysis; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control; D011733:Pyridoxamine / Q000627:therapeutic use; D011758:Pyrroles / Q000627:therapeutic use; D051381:Rats; D012307:Risk Factors; D009626:Terminology as Topic; D019737:Transplants
D006538:Heptanoic Acids; D010446:Peptide Fragments; D011758:Pyrroles; D011733:Pyridoxamine; D015935:Complement C4b; C032261:complement C4d; D000069059:Atorvastatin
Nefropatía crónica del trasplante.