A nonsymmetric pincer-catalyzed Suzuki-Miyaura arylation of benzyl halides and other nonactivated unusual coupling partners.
The catalytic activity of a PCN-type palladium pincer complex is evaluated in the construction of C(sp(2))-C(sp(2)) and C(sp(2))-C(sp(3)) bonds by Suzuki-Miyaura cross-couplings employing nontypical substrates such as benzyl halides, alpha-haloenones, or alkylboronic acids as coupling partners. Most of the reported reactions are achieved in aqueous media, with all of the advantages implied.
Inés
Blanca
B
Kimika Organikoa II Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, 644 P.K., 48080 Bilbao, Spain.
Moreno
Isabel
I
SanMartin
Raul
R
Domínguez
Esther
E
D002384:Catalysis; D004583:Electrons; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D010165:Palladium
D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated; D010165:Palladium