Metal-free one-pot oxidative amidation of aldoses with functionalized amines.
Metal-free one-pot oxidative amidation of aldoses with functionalized amines using iodine provides a rapid access to functionalized aldonamides. The main advantage of this approach relies on the fact that aldehyde oxidation and C-N bond formation are performed in a single synthetic operation.
Institut de Chimie Organique et Analytique, Université d'Orléans, CNRS UMR 6005, BP 6759, 45067 Orléans, France.
Ludovic
L
Colombeau
Ténin
T
Traoré
Philippe
P
Compain
Olivier R
OR
Martin
D000577:Amides / Q000138:chemical synthesis*; D000588:Amines / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D010100:Oxygen
D000577:Amides; D000588:Amines; D002241:Carbohydrates; D010100:Oxygen