[The effects of statins on the cerebral haemodynamics measured by transcranial Doppler in ischemic stroke patients].
OBJECTIVE
To evaluate the effects of statins on the cerebral haemodynamics of ischemic stroke patients with transcranial Doppler (TCD).


METHODS
70 inpatients with acute ischemic stroke were divided into two groups according whether they had taken statins after stroke. The change of the cerebral haemodynamics was studied in the two groups with TCD three months after stroke.


RESULTS
Three months later, the systolic flow velocities and mean flow velocities of bilateral middle cerebral arteries in the statins groups significantly increased (P <0.05). The pulse index of bilateral middle cerebral arteries in statins group significantly decreased (P <0.05). The flow velocities and pulse index of bilateral middle cerebral arteries in control group don't change significantly (P > 0.05).


CONCLUSIONS
Statins may have the effects of improving the situation of cerebral haemodynamics of patients with ischemic stroke.
Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jun-Ying
JY
Cai
Qiang
Q
Dong
Jian-Hui
JH
Fu
D000368:Aged; D001783:Blood Flow Velocity; D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods*
D000960:Hypolipidemic Agents