Taming data.
A challenge in systems-level investigations of the immune response is the principled integration of disparate data sets for constructing predictive models. InnateDB (Lynn et al., 2008; http://www.innatedb.ca), a publicly available, manually curated database of experimentally verified molecular interactions and pathways involved in innate immunity, is a powerful new resource that facilitates such integrative systems-level analyses.
Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA. aderem@systemsbiology.org
Alan
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Aderem
Ilya
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Shmulevich
D000818:Animals; D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D007113:Immunity, Innate