[Thyroid involvement in Wegener's granulomatosis: a case report].
Wegener's granulomatosis is a systemic necrotizing vasculitis affecting small to medium-sized vessels, characterized by involvement of the upper airways, lungs and kidneys. Endocrine involvement, particularly the thyroid gland is extremely rare. We report a 56-year-old woman presenting a limited form of Wegener's granulomatosis with the following clinical manifestations: sinusitis, pulmonary nodules, diabetes insipidus and a cold thyroid nodule. A right hemithyroidectomy was performed and the histopathological examination revealed a necrotizing vasculitis surrounded by granulomatous lesions. She was treated by corticosteroids without immunosuppressive therapy with a favourable outcome.
Service de médecine interne, CHU Farhat-Hached, avenue Ibn-Eljazzar, 4000 Sousse, Tunisie. mabrouk.khalifa@rns.tn
M
M
Khalifa
H
H
BenFredj
N
N
Ghannouchi
B
B
Sriha
A
A
Letaief
F
F
Bahri
D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D013961:Thyroid Gland / Q000473:pathology; D016606:Thyroid Nodule / Q000150:complications* / Q000601:surgery; D013965:Thyroidectomy / Q000379:methods
Atteinte thyroïdienne au cours de la granulomatose de Wegener : à propos d'un cas.