Cancer growth: predictions of a realistic model.
Simulations of avascular cancer growth are performed using experimental values of the relevant parameters. This permits a realistic assessment of the influence of these parameters on cancer growth dynamics. In general, an early exponential growth phase is followed by a linear regime (as observed in recent experiments), while the thickness of the viable cell layer remains approximately constant. Contrary to some predictions, a transition to latency is not observed.
Menchón
S A
SA
CONICET and FaMAF, Universidad Nacional de Córdoba, 5000-Córdoba, Argentina. menchon@famaf.unc.edu.ar
Condat
C A
CA
D000818:Animals; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000473:pathology*