Key roles for specific and nonspecific antibody in intestinal nematode expulsion.
Any future development of effective vaccines against intestinal parasitic nematodes requires in-depth understanding of host-parasite interactions. In this issue, McCoy et al. (2008) demonstrate important protective roles for host antibody against parasitic nematodes. These findings are not only of great practical importance, but also highlight how little we understand these important pathogens.
Horsnell
William G C
WG
International Centre for Genetic Engineering and Biotechnology, Cape Town, South Africa.
Brombacher
Frank
F
D000818:Animals; D000909:Antibodies, Helminth / Q000276:immunology*; D008954:Models, Biological; D009348:Nematoda / Q000276:immunology*; D009349:Nematode Infections / Q000276:immunology*
D000909:Antibodies, Helminth