[Dyslipidemia prevalence and its relationship with insulin resistance in a population of apparently healthy subjects].
OBJECTIVE
Evaluate dyslipidemia prevalence and its association with insulin resistance in a cohort of apparently healthy subjects.


METHODS
A cross-sectional study was conducted with 1,179 donors ages 35 to 65 years. The sample population was comprised of 71% men, with an average age of 44 +/- 7. Clinical records, anthropometric data, lipid profile, fasting glycaemia, and insulin levels were obtained.


RESULTS
Prevalence of hypertriglyceridemia was 57.3%, C-HDL under normal limits was 52.4%, and hypercholesterolemia was 48.7%. In addition, 36.8% of the obese individuals (as measured by waist perimeter) had hypertriglyceridemia/hypoalphalipoproteinemia, 35.2% had mixed dyslipidemia, and 33.4% had hypertriglyceridemia. Patterns of dyslipidemia were higher in subjects diagnosed with insulin resistance.


CONCLUSIONS
Insulin resistance associated with hypertriglyceridemia and hypoalphalipoproteinemia was common among our studied population. However, a significant proportion of cases of apparent healthy individuals continue to go undiagnosed.
Centro Médico Nacional Siglo XXI, Hospital de Especialidades, México. cmunguiam@yahoo.com.mx
Catarina
C
Munguía-Miranda
Reyna Gabriela
RG
Sánchez-Barrera
Daniel
D
Hernández-Saavedra
Miguel
M
Cruz-López
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D015331:Cohort Studies; D050171:Dyslipidemias / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000453:epidemiology; D015228:Hypertriglyceridemia / Q000097:blood / Q000453:epidemiology; D052456:Hypoalphalipoproteinemias / Q000097:blood / Q000453:epidemiology; D007333:Insulin Resistance; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000453:epidemiology; D015995:Prevalence; D014505:Urban Population; D055105:Waist Circumference
D001786:Blood Glucose
Prevalencia de dislipidemias en una población de sujetos en apariencia sanos y su relación con la resistencia a la insulina.