Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates.
Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.
Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. E.heikens@umcutrecht.nl
Esther
E
Heikens
Willem
W
van Schaik
Helen L
HL
Leavis
Marc J M
MJ
Bonten
Rob J L
RJ
Willems
D050260:Carbohydrate Metabolism / Q000235:genetics; D003428:Cross Infection / Q000382:microbiology*; D016984:Enterococcus faecium / Q000235:genetics* / Q000302:isolation & purification*; D023061:Gene Order; D005798:Genes, Bacterial; D044404:Genomic Islands; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology*