Packed with Salmonella--investigation of an international outbreak of Salmonella Senftenberg infection linked to contamination of prepacked basil in 2007.
Salmonella Senftenberg is uncommon in the United Kingdom. In January-June 2007, the Health Protection Agency reported on 55 primary human cases of Salmonella Senftenberg in England and Wales. In May 2007, fresh basil sold in the United Kingdom was found to be contaminated with Salmonella Senftenberg. We launched an investigation to elucidate the cause of this outbreak. Isolates were examined using plasmid profiling and pulsed-field gel electrophoresis, and the outbreak strain (SSFTXB.0014) was identified. We enquired via Enter-net whether other countries had isolated the outbreak strain, analyzed samples of fresh herbs from U.K. retailers, and interviewed patients on food history. Thirty-two patient-cases were referred to this outbreak in England and Wales. Onsets of illness occurred between 5 March and 6 June 2007. Fifty-six percent of patient-cases were females and 90% adults (>20 years old); three were admitted to hospital as a result of Salmonella infection. Scotland, Denmark, the Netherlands, and the United States reported on 19 cases of Salmonella Senftenberg infection presenting with the outbreak strain since January 2007. Eight samples of prepacked fresh basil imported from Israel tested positive with the same strain. A minority of patients could recall the consumption of basil before illness, and some reported consumption of products where basil was a likely ingredient. Environmental investigations in Israel did not identify the contamination source. Microbiological evidence suggested an association between contamination of fresh basil and the cases of Salmonella Senftenberg infection, leading to withdrawal of basil from all potentially affected batches from the U.K. market.
Pezzoli
Lorenzo
L
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Control (ECDC), Stockholm, Sweden. lorenzo.pezzoli@hpa.org.uk
Elson
Richard
R
Little
Christine L
CL
Yip
Hopi
H
Fisher
Ian
I
Yishai
Ruth
R
Anis
Emilia
E
Valinsky
Lea
L
Biggerstaff
Matthew
M
Patel
Nehal
N
Mather
Henry
H
Brown
Derek J
DJ
Coia
John E
JE
van Pelt
Wilfrid
W
Nielsen
Eva M
EM
Ethelberg
Steen
S
de Pinna
Elizabeth
E
Hampton
Michael D
MD
Peters
Tansy
T
Threlfall
John
J
D000328:Adult; D015373:Bacterial Typing Techniques; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D004739:England / Q000453:epidemiology; D005260:Female; D005511:Food Handling; D005516:Food Microbiology; D006801:Humans; D015994:Incidence; D007391:International Cooperation; D007557:Israel; D008297:Male; D031339:Ocimum / Q000382:microbiology*; D010957:Plasmids; D011159:Population Surveillance; D012478:Salmonella Food Poisoning / Q000453:epidemiology* / Q000209:etiology* / Q000382:microbiology; D019779:Salmonella enterica / Q000145:classification / Q000302:isolation & purification; D014852:Wales / Q000453:epidemiology