Dicobalt hexacarbonyl complexes of alkynyl imines in a sequential Staudinger/Pauson-Khand process. A route to new fused tricyclic beta-lactams.
Dicobalt hexacarbonyl complexes of alkynyl imines were allowed to react with ketenes via Staudinger reaction. Sequential [2 + 2] cycloaddition/Pauson-Khand reaction led to structurally new fused-tricyclic beta-lactams and fused-azabicyclic cyclopentenones. Chemoselectivity, scope, and limitation of the process were investigated.
Laboratoire de Chimie Moléculaire Organique, LCP UMR 6264, boite 562, Université Paul Cézanne, Faculté des Sciences St. Jérôme, Avenue Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France.
Clarisse
C
Olier
Nadia
N
Azzi
Gérard
G
Gil
Stéphane
S
Gastaldi
Michèle P
MP
Bertrand