[Clinical analysis on syphilis with sensorineural deafness].
OBJECTIVE
To investigate the clinical presentation, diagnosis and therapy of syphilis with sensorineural deafness.


METHODS
Three patients of syphilis with sensorineural deafness were analyzed including the clinical manifestation, serum and therapy response.


RESULTS
Three patients of syphilis with sensorineural deafness: 2 cases with rapid plasma reagin (RPR) and treponema pallidum particle agglutination (TPPA) positive, 1 case with RPR negative and TPPA positive; 2 cases had been diagnosed with syphilis and treated once; 2 cases with sudden sensorineural deafness and tinnitus, 1 case with tinnitus and high-frequency hearing loss. All cases hadn't another identified cause of the hearing loss or tinnitus. Their hearing loss level weren't improved after therapy.


CONCLUSIONS
Sudden hearing loss or nervous tinnitus may be the clinical manifestations of syphilis with sensorineural deafness. It is easy to miss diagnosis in clinical work. Some lab examinations were necessary to diagnose the cases with the etiology unknown of hearing loss, tinnitus or nystagmic.
Department of Otorhinolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510120, China.
Shaoyan
S
Zhang
Yaodong
Y
Xu
Jian
J
Gong
Yiqing
Y
Zheng
Suijun
S
Chen
Shufang
S
Ji
D000328:Adult; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013587:Syphilis / Q000150:complications