Retroperitoneal malignant solitary fibrous tumor of the small pelvis causing recurrent hypoglycemia by secretion of insulin-like growth factor 2.
A 28-yr-old man presented with recurrent reduced consciousness, generalized seizures of unknown etiology, recurrent hypoglycemia, psychomotor retardation, and grade 2 ectasia of the left kidney. Abdominal computed tomography (CT) and positron emission tomography (PET) scans demonstrated a well-circumscribed suprapubic pelvic mass, measuring 18 x 15 x 11 cm, with involvement of para-aortic lymph nodes and dilatation of the left ureter suggestive of an extragonadal testicular tumor. We excised the tumor by laparotomy, and it was confirmed to be a solitary fibrous tumor (SFT). After surgery and R0 tumor resection, the patient had no further evidence of hypoglycemia or of recurrence.
Wagner
Sigrid
S
Department of Urology and Kidney Transplantation, Martin Luther University, Ernst Grube Str. 40, 06120 Halle, Saale, Germany. sigrid.wagner@medizin.uni-halle.de
Greco
Francesco
F
Hamza
Amir
A
Hoda
Rashid M
RM
Holzhausen
Hans Jürgen
HJ
Fornara
Paolo
P
D000328:Adult; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism*; D008297:Male; D012008:Recurrence; D012186:Retroperitoneal Neoplasms / Q000150:complications* / Q000378:metabolism*; D054364:Solitary Fibrous Tumors / Q000150:complications* / Q000378:metabolism*
D007335:Insulin-Like Growth Factor II