The nephrotic syndrome: an unusual case of multiple embolic events.
The nephrotic syndrome is an unusual cause of the hypercoaguable state and thromboembolic complications. Here we report the case of a 42-year-old woman with nephrotic syndrome who presented with a pulseless lower extremity and a midpole renal infarct requiring urgent embolectomy of the leg. During her embolic evaluation, she was found to have an intracardiac thrombus. Over the course of her hospitalization, she developed a pulseless upper extremity and required an embolectomy of her arm. We believe that this represents the first case report of a patient with nephrotic syndrome, intracardiac thrombus, and evidence of embolization to 3 sites: kidney, arm, and leg.
Emory University School of Medicine, Department of Surgery, Grady Memorial Hospital, Atlanta, Georgia 30303, USA.
Jean-Claude D
JC
Schwartz
Amy D
AD
Wyrzykowski
Christopher J
CJ
Dente
Jeffrey M
JM
Nicholas
D000328:Adult; D000686:Amyloidosis / Q000150:complications*; D000925:Anticoagulants / Q000627:therapeutic use; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000209:etiology* / Q000628:therapy; D001777:Blood Coagulation; D001916:Brachial Artery; D017128:Embolectomy; D004617:Embolism / Q000097:blood / Q000209:etiology* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D005263:Femoral Artery; D006331:Heart Diseases / Q000097:blood / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007668:Kidney / Q000098:blood supply; D035002:Lower Extremity / Q000098:blood supply; D009404:Nephrotic Syndrome / Q000097:blood / Q000150:complications* / Q000209:etiology; D012086:Reoperation; D013927:Thrombosis / Q000097:blood / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome; D034941:Upper Extremity / Q000098:blood supply
D000925:Anticoagulants