[Wegener's granulomatosis presenting with ischaemic stroke].
Wegener's granulomatosis (WG) is a systemic disease of unknown origin characterized by necrotizing granulomatous vasculitis that involves primarily the upper and the lower respiratory tracts and the kidneys. A 44-year-old woman presenting with unusual neurological manifestation is reported. The patient with multiple pulmonary round shadows and hilar lymphadenopathy on the chest X-ray pictures, suffered from sudden hemiparesis episode. Computed tomography revealed ischemic stroke focus. A diagnosis of WG was confirmed by histological examination of specimen obtained during open lung biopsy. During the combination chemotherapy with prednisolone and cyclophosphamide, neurological symptoms decreased and clinical condition significantly improved.
Klinika Chorób Wewnetrznych Klatki Piersiowej Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Maria
M
Wieteska
Liliana
L
Wawrzyńska
Elzbieta
E
Wiatr
Mariusz
M
Chabowski
Iwona
I
Bestry
Marcin
M
Kurzyna
Adam
A
Torbicki
D000328:Adult; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage; D011859:Radiography; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging*
D003520:Cyclophosphamide; D011239:Prednisolone
Udar niedokrwienny mózgu w przebiegu ziarniniakowatości Wegenera.