[Adventitious diagnosis of coeliac disease in three family members].
This report presents family that among three of four family members (father, daughter, son) coeliac disease was diagnosed. The first diagnosed person was 11-year-old girl who was included into population screening tests for coeliac disease. Father has been presented chronic diarrhoea since childhood. Son has been suffering from recurrent aphthous stomatitis for many years. The girl was completely asymptomatic. The serum antiendomysial antibodies were positive in a high titre in all three patients. They all also presented macroscopic markers of coeliac disease in form of loss of folds, scalloping or mosaic pattern in the descending part of the duodenum and typical histopathological lesions graded as 3b or 3c according to Marsh classification.
Szaflarska-Popławska
Anna
A
Department of Paediatrics, Allergology and Gastroenterology, Nicolaus Copernicus University, Toruń, Collegium Medicum in Bydgoszcz, Poland. klped@cm.umk.pl
Popławski
Cezary
C
Mierzwa
Grazyna
G
D000328:Adult; D002446:Celiac Disease / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis; D004386:Duodenum / Q000473:pathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000175:diagnosis
Przypadkowe rozpoznanie celiakii u trzech członków rodziny.