Short-coupled variant of Torsade de Pointes as a cause of electrical storm and aborted sudden cardiac death: insights into mechanism and treatment.
This case report describes a 50-year-old woman with normal repolarization duration who survived multiple electrical storms and cardiac arrest related to recurrent short-coupled torsade de pointes (TdP). Overdrive ventricular pacing could not prevent malignant TdP, but exposed a pause-related TdP initiation pattern. Isoproterenol and atrial pacing completely suppressed TdP, suggesting that ventricular pacing may entail vulnerability to this condition.
Cardiology Department, Patras University Hospital, Rion, Patras, Greece. chil@otenet.gr
John A
JA
Chiladakis
Georgios
G
Spiroulias
Nikolaos
N
Koutsogiannis
Fani
F
Zagli
Dimritrios
D
Alexopoulos
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D016757:Death, Sudden, Cardiac / Q000209:etiology* / Q000517:prevention & control; D015716:Electrocardiography, Ambulatory; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008875:Middle Aged; D016171:Torsades de Pointes / Q000150:complications* / Q000503:physiopathology / Q000628:therapy
D000318:Adrenergic beta-Agonists; D007545:Isoproterenol