[Hyperprolactinaemia--like symptoms in Wilson's disease].
Wilson's disease is a rare genetic disorder of copper metabolism with a hepatic or neurological presentation. Wilson's disease may occur under a variety of clinical conditions. The complex clinical presentation causes that the diagnosis rests on a high index of suspicion. We present an atypical case of this disorder in a 22-year-old woman, in whom initial clinical picture (oligomenorrhea/amenorrhea symptoms and galactorrhea) suggested the presence of prolactinoma or the other forms of hyperprolactinaemia. After the diagnosis was established and zinc sulphate treatment implemented, her clinical status improved considerably. The present report suggests that Wilson's disease should be taken into account in a differential diagnosis of galactorrhea of an unknown origin and in patients with hyperprolactinaemia-like symptoms when prolactin level is within the normal limits.
Department of Internal Diseases and Clinical Pharmacology, Silesian Medical University, Katowice, Poland. r.krysiak@poczta.onet.pl
Robert
R
Krysiak
Bogusław
B
Okopień
D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006527:Hepatolenticular Degeneration / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006966:Hyperprolactinemia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D015175:Prolactinoma / Q000175:diagnosis; D019287:Zinc Sulfate / Q000627:therapeutic use
D019287:Zinc Sulfate
Choroba Wilsona o obrazie klinicznym zblizonym do hiperprolaktynemii.