Synthesis of FF8181-A.
Both enantiomers of FF8181-A were synthesized through optical resolution from the known Diels-Alder reaction product in 15 steps. The absolute configuration of the natural product was determined to be 1S,5S,5aS,9aS,9bS.
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Noriaki
N
Kobayashi
Hidenobu
H
Kuniyoshi
Ken
K
Ishigami
Hidenori
H
Watanabe
D002210:Caprylates / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry
D002210:Caprylates; C534016:FF8181-A; D009930:Organic Chemicals; D012717:Sesquiterpenes