Early metastatic spread after a complete response in locally advanced vulvar cancer treated with neoadjuvant chemoradiation: a case report.
BACKGROUND
Preoperative chemoradiation for advanced vulvar cancer reduces the tumor size and decreases morbidity from operative resection.


METHODS
A woman with locally advanced vulvar cancer had no evidence of metastatic disease at presentation. She displayed complete resolution of her vulvar and groin disease but developed early metastatic spread to the lungs and bone.


CONCLUSIONS
Despite excellent local control, patients with locally advanced vulvar cancer are at risk for early metastatic spread. The effect of delayed surgical intervention, ifany, is unknown.
Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York, USA. nishabansal1@yahoo.com
Nisha
N
Bansal
Carmel J
CJ
Cohen
Jinesh N
JN
Shah
Peter B
PB
Schiff
Thomas J
TJ
Herzog
Jason D
JD
Wright
D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy*; D017024:Chemotherapy, Adjuvant; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D020360:Neoadjuvant Therapy; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*