Simplex-optimized chromatographic resolution of selected ionic liquid cations utilizing a polar reversed-phase system.
This study reports on optimization of the RP-HPLC separation of imidazolium and pyridinium ionic liquid cations using a variable-size simplex algorithm. Under the optimized conditions, all critical pairs of ionic liquids were successfully separated in a single chromatographic run. The mobile phase at the point corresponding to the optimum consisted of 10% MeOH and 90% 15 mM KH(2)PO(4)/H(3)PO(4) with pH 3.43. The coefficients of asymmetry for all of the compounds analyzed at the simplex algorithm optimum ranged from 0.83 to 2.91.
Department of Environmental Analysis, Faculty of Chemistry, University of Gdańsk, Poland.
Joanna
J
Nichthauser
Monika
M
Paszkiewicz
Andrzej C
AC
Składanowski
Piotr
P
Stepnowski
D000465:Algorithms; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007093:Imidazoles / Q000302:isolation & purification; D052578:Ionic Liquids / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000302:isolation & purification
D007093:Imidazoles; D052578:Ionic Liquids; D011726:Pyridinium Compounds; C029899:imidazole