Subcutaneous fistulae in a patient with femoral hypoplasia due to Actinomyces europaeus and Actinomyces turicensis.
Infections due to Actinomyces europaeus or Actinomyces turicensis have only rarely been reported. We describe a case of chronic fistulae caused by a coinfection with A. europaeus and A. turicensis in an immunocompetent male patient with a severe congenital femur hypoplasia. Actinomycosis is most probably the consequence of a postoperative wound infection after a prior surgical intervention. Both Actinomyces species were identified by 16S rRNA gene sequencing. The Actinomyces-caused fistulae were treated by excision and a 1-week course of i.v. vancomycin followed by a 1-week course of p.o. cefuroxime.
Institute of Medical Microbiology, Virology and Hygiene, University Hospital Rostock, Schillingallee 70, 18057, Rostock, Germany. andreas.zautner@med.uni-rostock.de
A E
AE
Zautner
S
S
Schmitz
C
C
Aepinus
A
A
Schmialek
A
A
Podbielski
D000190:Actinomyces / Q000145:classification / Q000302:isolation & purification*; D000196:Actinomycosis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D000935:Antifungal Agents / Q000627:therapeutic use; D002444:Cefuroxime / Q000627:therapeutic use; D005269:Femur / Q000002:abnormalities*; D005402:Fistula / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D006801:Humans; D007121:Immunocompetence; D007719:Knee Joint / Q000382:microbiology; D038061:Lower Extremity Deformities, Congenital / Q000150:complications / Q000601:surgery; D008297:Male; D012329:RNA, Bacterial / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D018461:Soft Tissue Infections / Q000150:complications* / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000150:complications*; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
D000935:Antifungal Agents; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D014640:Vancomycin; D002444:Cefuroxime