Predicting osteoporosis in patients with a low-energy fracture.
The multicenter cross-sectional study was designed to develop a simple rule to predict the risk of osteoporosis in the patients with a low-energy fracture (LEF). Furthermore, we aimed to investigate the incidence of fall-related risk factors. We included 206 patients with age over 50 and an LEF at the emergency room. All patients underwent osteoporosis and fall risk assessment and dual-energy X-ray absorptiometry (DEXA) of both hips and the lumbar spine. The incidence of osteoporosis in our study population was 41% (84 cases of 206). Fifty-four percent of the patients reported at least one fall-related risk factor. Mobility problems occurred in 31% and osteoarthritis in 19%. The final osteoporosis prediction rule included age, positive family history, immobility, and low-body weight. The discrimination of the rule after correction for over-optimism was good (receiver operating curve (ROC)=ROC area=0.79). This simple rule may be helpful to select patients who need further osteoporosis assessment.
Timmer
Monique H M
MH
Department of Geriatric Medicine, University Medical Center Utrecht, Heidelberglaan 100, P.O. Box 85.500 (room B05.256), 3508 GA Utrecht, The Netherlands.
Samson
Monique M
MM
Monninkhof
Evelyn M
EM
De Ree
Ben
B
Verhaar
Harald J J
HJ
D000058:Accidental Falls / Q000706:statistics & numerical data; D000368:Aged; D015519:Bone Density; D003430:Cross-Sectional Studies; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis* / Q000453:epidemiology*; D011446:Prospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires