Congenital nephrotic syndrome masquerading as respiratory illness.
Congenital nephrotic syndrome is rare and is often found incidentally while investigating other disorders. The diagnosis is made by typical clinical features and laboratory tests in infants < 3 months of age. It may be inherited, sporadic, acquired, or associated with a syndrome. We present the case of a former premature infant with respiratory distress at 3 months of age who was subsequently diagnosed with Finnish-type congenital nephrotic syndrome resulting from an unusual mode of inheritance.
Aslam
Muhammad
M
Harvard Medical School, Boston, Massachusetts, USA. Muhammad.Aslam@childrens.harvard.edu
DeGrazia
Michele
M
Hossain
Tanzeema
T
D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007677:Kidney Function Tests; D016030:Kidney Transplantation; D008297:Male; D009404:Nephrotic Syndrome / Q000151:congenital* / Q000473:pathology* / Q000628:therapy; D006435:Renal Dialysis / Q000379:methods; D051437:Renal Insufficiency / Q000175:diagnosis / Q000628:therapy*; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome