Management of the upper airway and congenital cystic lung diseases in neonates.
Congenital upper airway obstruction can pose difficult problems immediately after birth. Newer strategies to maintain the airway in such situations include pharyngeal ventilation, the laryngeal mask airway and flexible fibreoptic intubation. These methods have decreased the potential for malformations such as Pierre Robin sequence to cause perinatal hypoxia. The most devastating upper airway problem is total obstruction at the supraglottic, glottic or tracheal level without tracheo-oesophageal communication. This can usually be detected prenatally and its management may include the use of the EXIT (ex-utero intrapartum) procedure. Congenital space-occupying lesions of the lung can be detected prenatally with ultrasound. Their management must be individualised, as their pre- and postnatal development is difficult to predict. Very large lesions can lead to lung hypoplasia or fetal hydrops. Management may include prenatal surgery, shunting and, rarely, an EXIT procedure during birth. A few children may require extracorporeal membrane oxygenation postnatally.
University Children's Hospital, Dr. v. Haunersches Kinderspital, Munich, Germany. tnicolai@med.uni-muenchen.de
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D000402:Airway Obstruction / Q000209:etiology / Q000628:therapy*; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications / Q000628:therapy*; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011656:Pulmonary Emphysema / Q000209:etiology / Q000601:surgery; D012121:Respiration, Artificial