Liquid chromatography-time-of-flight mass spectrometry analysis of 1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane and related compounds: separation of an eleven component mixture.
A method of separation for an eleven component mixture comprised of 1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane (4) and its derivatives has been developed using LC-time-of-flight-MS. All analytical figures of merit for compounds 1-11 have been determined. Compound 4 was examined in a substrate extraction study consisting of different sand and soil matrices, and a hydrolysis study of 4 on sand revealed an extremely complex degradation pathway which appeared to be concentration dependent. Substrate extraction and hydrolysis results where compared with sulfur mustard (HD).
Winemiller
Mark D
MD
Research and Technology Directorate, U.S. Army Edgewood Research, Edgewood Chemical Biological Center (ECBC), Aberdeen Proving Ground, MD 21010-5424, USA.
Bae
Sue Y
SY
D002619:Chemical Warfare Agents / Q000032:analysis; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D006868:Hydrolysis; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D009151:Mustard Gas / Q000031:analogs & derivatives* / Q000032:analysis*; D012680:Sensitivity and Specificity; D012987:Soil / Q000032:analysis
C533976:1-(2-chloroethoxy)-2-((2-chloroethyl)thio) ethane; D002619:Chemical Warfare Agents; D006843:Hydrocarbons, Chlorinated; D012987:Soil; D009151:Mustard Gas