The human polysaccharide- and protein-specific immune response to Streptococcus pneumoniae is dependent on CD4(+) T lymphocytes, CD14(+) monocytes, and the CD40-CD40 ligand interaction.
Leen
L
Moens
Greet
G
Wuyts
Louis
L
Boon
Marcel T
MT
den Hartog
Jan L
JL
Ceuppens
Xavier
X
Bossuyt
D000818:Animals; D016667:Bacterial Capsules / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D019013:CD40 Antigens / Q000276:immunology*; D023201:CD40 Ligand / Q000276:immunology*; D002450:Cell Communication / Q000276:immunology; D006801:Humans; D018950:Lipopolysaccharide Receptors / Q000276:immunology*; D051379:Mice; D016513:Mice, SCID; D009000:Monocytes / Q000378:metabolism*; D011008:Pneumococcal Infections / Q000276:immunology; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013296:Streptococcus pneumoniae / Q000276:immunology*
D001426:Bacterial Proteins; D019013:CD40 Antigens; D018950:Lipopolysaccharide Receptors; D011135:Polysaccharides, Bacterial; D023201:CD40 Ligand