[Studies on flavonoid glycosides of Sarcandra glabra].
OBJECTIVE
To in vestigate the chemical constituents of Sarcandra glabra and obtain a more comprehensive understanding on its effective components.


METHODS
The constituents were isolated by various column chromatographic method and their structures were elucidated by physico-chemical properties and spectroscopic analysis.


RESULTS
Five flavonoid glycosides were isolated and identified as kaempferol-3-O-beta-D-glucuronide (1), quercetin-3-O-alpha-D-glucuronide (2), quercetin-3-O-beta-D-glucuronopyranoside methyl ester (3), 5, 7, 4'-trihydroxy-8-C-beta-D-glucopyranosyl flavanone (4), neoastilbin (5), 5-O-caffeoylquinic acid methyl ester (6), 3, 4-dihydroxybenzoic acid (7), isofraxidin (8).


CONCLUSIONS
Compounds 1-6 were isolated from the genus Sarcandra for the first time. The glucuroide compounds compounds 1-3, were first isolated from the genus Sarcandra.
School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
Ming-ju
MJ
Huang
Guang-yao
GY
Zeng
Jian-bing
JB
Tan
Yan-lan
YL
Li
Gui-shan
GS
Tan
Ying-jun
YJ
Zhou
D002109:Caffeic Acids / Q000737:chemistry; D003374:Coumarins / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry*; D020719:Glucuronides / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D002109:Caffeic Acids; D003374:Coumarins; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D020719:Glucuronides; D006027:Glycosides; C008182:isofraxidin