Nanophthalmos and acquired retinoschisis.
OBJECTIVE
To report three cases of nanophthalmos associated with acquired (senile) retinoschisis.


METHODS
Observational case series.


METHODS
Complete ophthalmologic evaluation (including funduscopy with scleral indentation, total axial length measurement with A-scan, optical coherence tomography [Stratus 3 OCT; Carl Zeiss Meditec Inc, Dublin, California, USA], and fundus photography) of three consecutive patients presenting with nanophthalmos and acquired retinoschisis.


RESULTS
Three patients with nanophthalmos presented with bilateral acquired retinoschisis. One patient underwent a course of systemic steroids to treat concurrent and bilateral uveal effusion with macular edema. In this patient, one eye responded to this course of therapy without recurrence, while the fellow eye required vortex vein decompression with scleral windows, with subsequent, successful resolution. The average follow-up period was 40 months (range, eight to 95 months). Retinoschisis cavities remained stationary in each case.


CONCLUSIONS
Bilateral acquired retinoschisis may occur in patients with nanophthalmos, suggesting that there may be correlation in the mechanisms underlying these ocular disorders.
Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University, New York, New York, USA. eg2119@columbia.edu
Elona
E
Dhrami-Gavazi
William M
WM
Schiff
Gaetano R
GR
Barile
D000328:Adult; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000209:etiology; D008297:Male; D008850:Microphthalmos / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D010781:Photography; D041441:Retinoschisis / Q000175:diagnosis / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014603:Uveal Diseases / Q000209:etiology; D014792:Visual Acuity