Chiral counteranion-aided asymmetric hydrogenation of acyclic imines.
When combined with a chiral phosphate counteranion, a chiral diamine-ligated Ir(III) catalyst displayed excellent enantioselectivities in the asymmetric hydrogenation of a wide range of acyclic imines, affording chiral amines in up to 99% ee.
Li
Chaoqun
C
Department of Chemistry, Liverpool Centre for Materials and Catalysis, University of Liverpool, Liverpool L69 7ZD, UK.
Wang
Chao
C
Villa-Marcos
Barbara
B
Xiao
Jianliang
J
D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D003959:Diamines / Q000737:chemistry; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry; D010755:Organophosphates / Q000737:chemistry; D013237:Stereoisomerism
D000588:Amines; D003959:Diamines; D007097:Imines; D009942:Organometallic Compounds; D010755:Organophosphates; D007495:Iridium