Ultrasound findings in trisomy 22.
We sought to identify the characteristic sonographic findings of fetal trisomy 22 by performing a retrospective review of nine cases of fetal trisomy 22. All cases of chromosomal mosaicism were excluded, as were first-trimester losses. Indications for sonography, gestational age, and sonographically detected fetal anomalies were analyzed. The majority of patients were referred for advanced maternal age or abnormal ultrasound findings on screening exam. Oligohydramnios was the most common sonographic finding, present in 55% of affected fetuses. Intrauterine growth restriction and increased nuchal thickness were slightly less frequent.
Schwendemann
Wade D
WD
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. schwendemann.wade@mayo.edu
Contag
Stephen A
SA
Koty
Patrick P
PP
Miller
Richard C
RC
Devers
Patricia
P
Watson
William J
WJ
D004314:Down Syndrome / Q000000981:diagnostic imaging*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008403:Mass Screening; D009030:Mosaicism; D048208:Nuchal Translucency Measurement; D016104:Oligohydramnios / Q000000981:diagnostic imaging*; D011247:Pregnancy; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal