Cutaneous malignant melanoma metastatic to a uterine leiomyoma: a case report.
BACKGROUND
Malignant melanoma is the sixth-most-common cancer in the United States and can spread throughout the body. This report represents the second case of a cutaneous melanoma involving a uterine leiomyoma.


METHODS
A 49-year-old woman presented with an inguinal mass; biopsy revealed an undifferentiated neoplasm. Further examination and computed tomography revealed an enlarged, fibroid uterus. The patient underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy and right inguinal lymphadenectomy. Histologic examination of the inguinal lymph node and the leiomyoma revealed metastatic melanoma.


CONCLUSIONS
As the incidence of melanoma increases, metastasis to unusual locations, such as uterine fibroids, probably will be encountered more frequently.
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Ryan T
RT
Bakelaar
John T
JT
Soper
Christopher V
CV
Lutman
D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008545:Melanoma / Q000556:secondary*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology / Q000556:secondary*