[Study of anti-oxidant phenolic compounds from stem barks of Morus yunanensis].
OBJECTIVE
To study anti-oxidant phenolic compounds from stem barks of Morus yunanensis.


METHODS
Isolation and purification were carried out by silica gel, Sephadex LH -20 and RP - 18 column chromatography. The chemical structures of constituents were elucidated on the basis of physicochemical properties and spectral data.


RESULTS
Eight phenolic compounds were isolated and identified as: mulberrofuran E (1), mulberrofuran K (2), albanol B (3), kuwanon H (4), resveratrol (5), moracin M (6), morachalcone A (7), 3', 5', 2, 4-tetrahydroxy-4-(3-methyl-1-butenyl) stilbene (8).


CONCLUSIONS
All the compounds were isolated from the plant for the first time, and compounds 2, 3, 6, 8 showed potent anti-oxidation activities.
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Xi-Qiang
XQ
Cui
Hong-Qing
HQ
Wang
Chao
C
Liu
Ruo-Yun
RY
Chen
D000818:Animals; D000975:Antioxidants / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D031625:Morus / Q000737:chemistry*; D010084:Oxidation-Reduction / Q000187:drug effects; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D024301:Plant Bark / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D051381:Rats; D013055:Spectrophotometry, Infrared
D000975:Antioxidants; D010636:Phenols