Extramedullary peritoneal hematopoiesis combined with tuberculosis in a patient with primary myelofibrosis.
Primary myelofibrosis (PMF) is a myeloproliferative disorder characterized by bone marrow fibrosis or dysmegakaryocytes, extramedullary hematopoiesis, and the presence of JAK2 mutations. We present a 73-year-old man with PMF that had a fulminant clinical course. Peritoneal extramedullary hematopoiesis combined with tuberculosis was found 4 months after the diagnosis. This combination of complications has not been previously reported. These events were followed by rapid leukemic transformation and the patient's death.
Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea.
Su-Jung
SJ
Kim
Yenna
Y
Lee
Sung-Han
SH
Kim
Haeryoung
H
Kim
Kyoung-Un
KU
Park
Soo-Mee
SM
Bang
Jong-Seok
JS
Lee
D000368:Aged; D001201:Ascites / Q000000981:diagnostic imaging; D017809:Fatal Outcome; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics; D008297:Male; D009154:Mutation; D010537:Peritoneum / Q000473:pathology*; D014395:Peritonitis, Tuberculous / Q000150:complications* / Q000000981:diagnostic imaging; D055728:Primary Myelofibrosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography
D053614:Janus Kinase 2