[Severe bouts of neuromyelitis optica: dramatic improvement after plasma exchanges].
Severe relapses are common in neuromyelitis optica (NMO). Plasma exchanges (PE) were successfully used to treat acute demyelinating relapses resistant to corticosteroids. However, little is known about PE efficiency in NMO relapses, particularly in relation with the presence or not of specific antibodies. We here report two patients with NMO (one seropositive and one seronegative) with dramatic improvement after PE on both the optical and spinal involvement.
Bonnan
M
M
Service de neurologie et neurovasculaire, groupe hospitalier Paris Saint-Joseph, 75014 Paris, France. mickael_bonnan@yahoo.fr <mickael_bonnan@yahoo.fr>
Brasme
H
H
Diaby
M M
MM
Vlaicu
M
M
Le Guern
V
V
Zuber
M
M
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000503:physiopathology / Q000628:therapy*; D010951:Plasma Exchange / Q000379:methods*; D012008:Recurrence; D013116:Spinal Cord / Q000503:physiopathology; D016896:Treatment Outcome; D014785:Vision, Ocular
Poussées sévères de neuromyélite optique : efficacité spectaculaire des échanges plasmatiques.