[Severe bronchopneumonia in children: can Epstein-Barr virus serology be misleading?].
We report the cases of two young immunocompetent children with bronchopneumonia associating disabling, spastic cough and severe hypoxemia. In both patients, a primary Epstein-Barr Virus (EBV) infection had been suggested based on EBV presence in nasal secretions and a positive serology with anti-VCA immunoglobulin M. Nevertheless, the diagnosis was not confirmed. We discuss the problems confirming EBV responsibility in acute respiratory infections and the pitfalls of diagnostic tests.
Carsin
A
A
Unité de médecine infantile, CHU de la Timone-Enfants, 264, rue Saint-Pierre, 13385 Marseille cedex 05, France.
Bosdure
E
E
Zandotti
C
C
Mancini
J
J
Chabrol
B
B
Dubus
J-C
JC
D001996:Bronchopneumonia / Q000821:virology*; D002675:Child, Preschool; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D012698:Serologic Tests; D012720:Severity of Illness Index
Bronchopneumonies sévères chez l'enfant : la sérologie pour le virus d'Epstein-Barr peut-elle égarer ?