2-Phospha[3]ferrocenophanes with planar chirality: synthesis and use in enantioselective organocatalytic [3 + 2] cyclizations.
Planar chiral phosphines displaying a new ferrocenophane scaffold have been prepared via a stereoselective approach. The P-cyclohexyl substituted phosphine affords high levels of asymmetric induction in the organocatalytic [3 + 2] annulation reaction between allenes and electron-poor olefins.
Voituriez
Arnaud
A
Institut de Chimie des Substances Naturelles, CNRS UPR 2301-1, av. de la Terrasse, 91198 Gif-sur-Yvette, France.
Panossian
Armen
A
Fleury-Brégeot
Nicolas
N
Retailleau
Pascal
P
Marinetti
Angela
A
D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D058085:Iron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D003517:Cyclopentanes; D004952:Esters; D058085:Iron Compounds; D013141:Spiro Compounds