Primary peritonitis due to Streptococcus pyogenes with reduced susceptibility to fluoroquinolones.
We report the 1st case of primary peritonitis caused by Streptococcus pyogenes with a reduced susceptibility to fluoroquinolones in a healthy woman, leading to a clinical and microbiological treatment failure. DNA sequencing of parC and gyrA revealed the association of the following 3 substitutions in ParC: Ser80Pro, Asp91Asn, and Ser140Pro.
Doloy
Alexandra
A
Microbiologie, Centre Hospitalier de Versailles, Le Chesnay 78157, France.
Godin
Claire
C
Decousser
Jean-Winoc
JW
Panel
Pierre
P
Greder-Belan
Alix
A
Doucet-Populaire
Florence
F
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D024841:Fluoroquinolones / Q000494:pharmacology*; D006801:Humans; D010538:Peritonitis / Q000188:drug therapy / Q000382:microbiology*; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones