Characterization of bZip-type transcription factor AtfA with reference to stress responses of conidia of Aspergillus nidulans.
Microorganisms growing in natural habitats are permanently confronted with a wide variety of external stresses. In fungi, including Aspergillus nidulans, one of the general and ultimate strategies to survive in harsh habitats is the development of stress-tolerant conidia. In this study, we found that one of the basic-region leucine zipper transcription factors, named AtfA, plays a crucial role in the acquisition of tolerance against oxidative and heat stress on conidia, but not on mycelia, although this factor is not involved in asexual development per se.
Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Nagoya, Japan. dhaggy@niche.tohoku.ac.jp
Daisuke
D
Hagiwara
Yoshihiro
Y
Asano
Takafumi
T
Yamashino
Takeshi
T
Mizuno
D001233:Aspergillus nidulans / Q000235:genetics / Q000378:metabolism*; D050976:Basic-Leucine Zipper Transcription Factors / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D017353:Gene Deletion; D018869:Heat-Shock Response; D009154:Mutation / Q000235:genetics; D018384:Oxidative Stress
D050976:Basic-Leucine Zipper Transcription Factors; D005656:Fungal Proteins