Protein kinases of malaria parasites: an update.
Protein kinases (PKs) play crucial roles in the control of proliferation and differentiation in eukaryotic cells. Research on protein phosphorylation has expanded tremendously in the past few years, in part as a consequence of the realization that PKs represent attractive drug targets in a variety of diseases. Activity in Plasmodium PK research has followed this trend, and several reports on various aspects of this subject were delivered at the Molecular Approaches to Malaria 2008 meeting (MAM2008), a sharp increase from the previous meeting. Here, the authors of most of these communications join to propose an integrated update of the development of the rapidly expanding field of Plasmodium kinomics.
Doerig
Christian
C
INSERM U609, Wellcome Centre for Molecular Parasitology, University of Glasgow Biomedical Research Centre, Glasgow G12 8TA, Scotland, UK. cdoer001@udcf.gla.ac.uk
Billker
Oliver
O
Haystead
Timothy
T
Sharma
Pushkar
P
Tobin
Andrew B
AB
Waters
Norman C
NC
D000818:Animals; D008958:Models, Molecular; D010961:Plasmodium / Q000201:enzymology* / Q000235:genetics; D011487:Protein Conformation; D011494:Protein Kinases / Q000737:chemistry / Q000378:metabolism*
D011494:Protein Kinases