Occurrence of a USA300 vancomycin-intermediate Staphylococcus aureus.
A vancomycin-intermediate Staphylococcus aureus (VISA) isolated from the blood of a 46-year-old patient with endocarditis was determined to be pulsed-field type USA300, daptomycin nonsusceptible, and positive for the Panton-Valentine leukocidin genes. Development of the VISA phenotype does not appear limited to traditional health care strains of S. aureus.
Hageman
Jeffrey C
JC
Centers for Disease Control and Prevention, Atlanta, GA 30033, USA. jhageman@cdc.gov
Patel
Jean
J
Franklin
Patrick
P
Miscavish
Karen
K
McDougal
Linda
L
Lonsway
David
D
Khan
Fazle N
FN
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D004697:Endocarditis, Bacterial / Q000097:blood / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000097:blood / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D014640:Vancomycin