[Clinical impact of appropriate use of antibiotic in hospital according to CARAT criteria].
In response to the overuse and misuse of antibiotics, leading to increasing bacterial resistance and the decreasing development of new antibiotics, the Council for Appropriate and Rational Antibiotic Therapy (an independent, interdisciplinary panel of healthcare professionals established to advocate the appropriate use of antibiotics) has developed criteria to guide proper antibiotic selection. These criteria include: establishment of a need to justify use of antibiotics (e.g., colonization versus disease); evidence-based results; therapeutic benefits; safety; use of pharmacodynamic indices for optimal drug and optimal duration; cost-effectiveness. Promoting the appropriate use of antibiotics should provide for optimal outcomes for our patients.
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Thomas M
TM
Infectious Disease Section, Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio, USA.
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology; D002986:Clinical Trials as Topic; D024901:Drug Resistance, Multiple, Bacterial; D004363:Drug Utilization; D005060:Europe / Q000453:epidemiology; D019317:Evidence-Based Medicine; D019983:Guideline Adherence; D006761:Hospitals / Q000592:standards*; D006801:Humans; D007362:Intensive Care Units; D016134:Organizational Policy; D010362:Patients' Rooms; D017410:Practice Guidelines as Topic
D000900:Anti-Bacterial Agents
L'impatto clinico dell'uso appropriato degli antibiotici in ospedale secondo i criteri del CARAT.