Exposure of infants to fumonisins in maize-based complementary foods in rural Tanzania.
Feeding children with maize may expose them to fumonisins (FBs). This study assessed FB exposure for infants consuming maize in Tanzania by modeling maize consumption data (kg/kg body weight (bw)/day) with previously collected total FB contamination (microg/kg) patterns for sorted and unsorted maize harvested in 2005 and 2006. Consumption was estimated by twice conducting a 24 h dietary recall for 254 infants. The exposure assessment was performed with the @RISK analysis software. Of the infants, 89% consumed maize from 2.37 to 158 g/person/day (mean; 43 g/person/day +/- 28). Based on the contamination for sorted maize; in 2005, the percentage of infants with FB exposures above the provisional maximum tolerable daily intake (PMTDI) of 2 microg/kg (bw) (26% (95% confidence interval (CI); 23-30)) was significantly higher than the level of 3% (90% CI; 2-12) in 2006. Pooling the datasets for sorted maize from the two seasons resulted in a seemingly more representative risk (10% (95% CI; 6-17)) of exceeding the PMTDI. However, infants who might have consumed unsorted maize would still be at a significantly higher risk (24% (95% CI; 15-34)) of exceeding the PMTDI. Sorting and other good maize management practices should be advocated to farmers in order to minimize FB exposure in rural areas.
Tanzania Food and Drugs Authority, Dar es Salaam, Tanzania.
Martin E
ME
Kimanya
Bruno
B
De Meulenaer
Katleen
K
Baert
Bendantunguka
B
Tiisekwa
John
J
Van Camp
Simbarashe
S
Samapundo
Carl
C
Lachat
Patrick
P
Kolsteren
D005506:Food Contamination; D037341:Fumonisins / Q000008:administration & dosage / Q000633:toxicity*; D006801:Humans; D007223:Infant; D020714:Maximum Tolerated Dose; D013636:Tanzania; D003313:Zea mays
D037341:Fumonisins