Cardiac resynchronization therapy improves the uptake of MIBI-99mTc and cardiac function.
This case shows the improvement promoted by cardiac resynchronization therapy (CRT) on myocardial perfusion and left ventricular (LV) performance assessed by gated myocardial perfusion scintigraphy. The patient had idiopathic dilated cardiomyopathy, left bundle branch block and severe heart failure despite optimized medical treatment. After CRT, clinical improvement, QRS reduction and improvement of previously hypoperfused anterior and septal walls were observed. There was also decrease in LV end-diastolic and systolic volumes and increase in LV ejection fraction.
Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil. simonecordis@cardiol.br
Simone Cristina Soares
SC
Brandão
Maria Clementina
MC
Giorgi
Silvana D'Orio
SD
Nishioka
Martino
M
Martinelli Filho
José
J
Soares
José Cláudio
JC
Meneghetti
D002037:Bundle-Branch Block / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013318:Stroke Volume / Q000502:physiology; D017256:Technetium Tc 99m Sestamibi; D013997:Time Factors; D016277:Ventricular Function, Left / Q000502:physiology*
D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi