Etanercept-induced lupus erythematosus presenting as a unilateral pleural effusion.
A 72-year-old man receiving etanercept for the treatment of psoriatic arthritis had an exudative pleural effusion with nonspecific fluid analysis and pleural biopsy findings. He was ultimately found to have drug-induced lupus erythematosus due to the etanercept. The spectrum of autoimmune disease due to the use of tumor necrosis factor inhibitors is reviewed.
Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT.
Jafar
J
Abunasser
Department of Anatomic Pathology and Laboratory Medicine, University of Connecticut School of Medicine, Farmington, CT.
Faripour A
FA
Forouhar
Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT. Electronic address: Metersky@nso.uchc.edu.
Mark L
ML
Metersky
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D010996:Pleural Effusion / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D018124:Receptors, Tumor Necrosis Factor
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept