Ghrelin and cell differentiation.
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a gastric hormone that has been found to have a wide variety of biological functions. This review summarizes our current understanding of the effects of ghrelin on cell differentiation and tissue development, with an emphasis on the lineage determination of mesenchymal stem cells.
Xu
Geyang
G
Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China.
Li
Yin
Y
An
Wenjiao
W
Zhang
Weizhen
W
D050156:Adipogenesis; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D019070:Cell Lineage; D054439:Ghrelin / Q000378:metabolism / Q000502:physiology*; D013006:Growth Hormone / Q000502:physiology; D006801:Humans; D008024:Ligands; D059630:Mesenchymal Stem Cells / Q000502:physiology; D008954:Models, Biological; D024510:Muscle Development; D009474:Neurons / Q000166:cytology; D010012:Osteogenesis; D036361:Peptide Hormones / Q000378:metabolism / Q000502:physiology*
D054439:Ghrelin; D008024:Ligands; D036361:Peptide Hormones; D013006:Growth Hormone