Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung.
Pulmonary sclerosing hemangioma is generally considered a rare neoplasm presenting as a solitary benign nodule. During routine medical examination multiple abnormal nodular shadows were detected in the right lower lung field on chest X-ray in a 48-year-old asymptomatic woman. The patient underwent wedge resection for the pulmonary lesion. The resected lung had numerous scattered tiny nodules and small nodules congregated together, forming larger nodules. All of these lesions had typical features of sclerosing hemangioma. The authors call this unusual growth pattern of sclerosing hemangioma a 'pneumonic pattern'. Adjacent to the largest lesion, a relatively well-defined small mucinous lesion composed of mucinous tall columnar cells and basaloid squamous cells was detected. Because this lesion did not have expression of thyroid transcription factor-1, it is described as mucinous adenomatous hyperplasia.
Choi
Keum H
KH
Department of Pathology, Chonbuk National University Medical School, San 2-20 Keumam-dong, Dukjin, Jeonju, Korea.
Baek
Hyun A
HA
Park
Ho S
HS
Jang
Kyu Y
KY
Jin
Gong-Yong
GY
Kim
Min H
MH
Lee
Yong C
YC
Moon
Woo S
WS
Chung
Myoung-Ja
MJ
D000236:Adenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D009687:Nuclear Proteins / Q000032:analysis; D011014:Pneumonia / Q000473:pathology; D047868:Pulmonary Sclerosing Hemangioma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors / Q000032:analysis
D014408:Biomarkers, Tumor; C000614412:NKX2-1 protein, human; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors