Lignans from the roots of Saururus chinensis.
Four new lignans, saucerneol F (1), saucerneol G (2), saucerneol H (3), and saucerneol I (4), were isolated from the EtOAc extract of the roots of Saururus chinensis, together with one known compound, saucerneol D (5). The structures of compounds 1-4 were elucidated by spectroscopic analysis. These compounds showed cytotoxic activities against HT-29, MCF-7, and HepG-2 cell lines.
College of Pharmacy, Yeungnam University, 214-1 Dae-dong, Gyeongsan, Korea.
Chang-Seob
CS
Seo
Ming-Shan
MS
Zheng
Mi-Hee
MH
Woo
Chong-Soon
CS
Lee
Sung-Ho
SH
Lee
Byeong-Seon
BS
Jeong
Hyeun-Wook
HW
Chang
Yurngdong
Y
Jahng
Eung-Seok
ES
Lee
Jong-Keun
JK
Son
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D007723:Korea; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D032134:Saururaceae / Q000737:chemistry*
D000972:Antineoplastic Agents, Phytogenic; D017705:Lignans