Monoterpene glycosides from Indigofera hetrantha.
Monoterpene glycosides have been isolated from the ethyl acetate soluble fraction of Indigofera hetrantha and their structures assigned to be 3,7-dimethyl-2(E),6-octadien-5-one-1-O-beta-D-6-O-acetylglucopyranoside (1) and 3,7-dimethyl-2(E), 6-octadien-5-one-1-O-[-beta-D-6''-O-acetylglucopyra-nosyl (1'' --> 6')-beta-D-glucopyranoside] (2), on the basis of spectroscopic analysis including 1D and 2D NMR techniques. Compounds 1 and 2 displayed moderate inhibitory potential against the enzyme lipoxygenase.
Pharmaceutical Research Centre, PCSIR Laboratories Karachi Complex, Karachi, Pakistan.
Sajid
S
Mehmood
Aziz-Ur-Rahman
Zaheer
Z
Ahmad
Nighat
N
Afza
Abdul
A
Malik
Habib
H
Ahmad
Muhammad Iqbal
MI
Choudhary
D004789:Enzyme Activation / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D029883:Indigofera / Q000737:chemistry*; D008084:Lipoxygenase / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry*
D006027:Glycosides; D039821:Monoterpenes; D008084:Lipoxygenase