Coverage of exposed bones and joints in critically ill patients: lower extremity salvage with topical negative pressure therapy.
BACKGROUND
Soft tissue defects of the limb with exposure of tendons and bones in critically ill patients usually lead to extremity amputation. A potential treatment with topical negative pressure may allow split-thickness skin grafting to the bone, which leads to limb salvage.


METHODS
We report on 21 multimorbid patients, 46 to 80 years of age, with severe lower limb soft tissue loss and infection with exposed bone following débridement with critical limb ischemia. Attempts to salvage the extremities were undertaken with repeated surgical débridement followed by vacuum-assisted closure therapy and subsequent split-thickness skin grafting procedures.


RESULTS
Infection control and limb salvage were achieved in all cases with multiple débridements, topical negative pressure therapy, and skin grafts. In all patients, the exposure of tendons and bones was reversible by this strategy without a free flap transfer.


CONCLUSIONS
The patients described in this study were severely compromised by systemic and vascular disorders, so extremity amputation had been considered owing to the overall condition and the exposure of tendons and bones. Since it was possible to salvage the affected limbs with this straightforward and simple procedure, this type of treatment should be considered as a last attempt to prevent amputation.
Horch
Raymund E
RE
Department of Plastic and Hand Surgery, Institute of Radiology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany. raymund.horch@uk-erlangen.de
Dragu
Adrian
A
Lang
Werner
W
Banwell
Paul
P
Leffler
Mareike
M
Grimm
Andreas
A
Bach
Alexander D
AD
Uder
Michael
M
Kneser
Ulrich
U
D000368:Aged; D000369:Aged, 80 and over; D016638:Critical Illness; D003646:Debridement; D005260:Female; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000473:pathology; D007871:Leg Ulcer / Q000473:pathology / Q000628:therapy*; D023821:Limb Salvage; D035002:Lower Extremity / Q000098:blood supply; D008875:Middle Aged; D009336:Necrosis; D054843:Negative-Pressure Wound Therapy; D016038:Skin Transplantation; D014945:Wound Healing