Amniotic membrane transplantation: indications and results.
OBJECTIVE
To describe amniotic membrane transplantation indications and results at the authors' institution.


METHODS
In this study, chart review of 108 patients who underwent amniotic membrane transplantation between January 2002 and April 2006 was performed. The survival rate of corneal integrity was compared, using Kaplan-Meier survival analysis, as a measure of success rate.


RESULTS
The mean age of the patients was 55.2+/-20.1 (6-87 years, 75 female, 51 male). The patients underwent amniotic membrane transplantation for six different diagnoses: nontraumatic corneal perforation (32 eyes, Group 1), persistent epithelial defect (29 eyes, Group 2), aphakic/pseudophakic bullous keratopathy (18 eyes, Group 3), infectious ulcer resistant to treatment (14 eyes, Group 4), necrotizing keratitis secondary to endophthalmitis (10 eyes, Group 5), and caustic injury (5 eyes, Group 6). The mean survival of corneal integrity was similar in all groups (p=0.156).


CONCLUSIONS
Amniotic membrane transplantation is a successful adjunctive method in achieving corneal epithelization in the study indications.
Department of Ophthalmology, Ankara Education and Research Hospital, Ankara - Turkey. drelvinyildiz@yahoo.com
E H
EH
Yildiz
A B
AB
Nurozler
N
N
Ozkan Aksoy
U E
UE
Altiparmak
M
M
Onat
H
H
Karaguzel
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D002648:Child; D003316:Corneal Diseases / Q000175:diagnosis* / Q000601:surgery*; D019573:Epithelium, Corneal / Q000502:physiology; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome