High genetic diversity of nontypeable Haemophilus influenzae isolates from two children attending a day care center.
Twenty-one nontypeable Haemophilus influenzae (NTHi) isolates from the throats of two healthy children were genotyped by multilocus sequence typing. Nine unique sequence types (STs) were identified. These STs were scattered throughout the phylogenetic tree of reported NTHi STs, demonstrating the high level of NTHi diversity found in colonized children.
Department of Pediatrics and Communicable Diseases, L2225 Women's Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0244, USA.
Nathan C
NC
Lacross
Carl F
CF
Marrs
Mayuri
M
Patel
Sara A
SA
Sandstedt
Janet R
JR
Gilsdorf
D015373:Bacterial Typing Techniques; D002648:Child; D002656:Child Day Care Centers; D016000:Cluster Analysis; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D005838:Genotype; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D010614:Pharynx / Q000382:microbiology; D010802:Phylogeny; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial