Polyketides from a marine sponge-derived fungus Mycelia sterilia and proton-proton long-range coupling.
A series of polyketide-originated metabolites (1-5) were isolated from a marine sponge-derived fungus Mycelia sterilia. Of these, 1-3 were new compounds. Their structures were elucidated by spectroscopic methods as (4R*, 5S*, 6S*, 8S*, 13R*)-1-(2,8-dihydroxy-1,2,6-trimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)-3-methoxy-propan-1-one (1), 4,8-dihydroxy-7-(2-hydroxy-ethyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one (2) and 1-methyl-naphthalene-2,6-dicarboxylic acid (3). In 1, the proton-proton long-range coupling phenomenon claimed attention and was discussed.
Hao
Gao
G
Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China.
Qing-Hua
Zhang
Z
Miao-Miao
Jiang
J
Jin-Shan
Tang
T
Cheng-Du
Miao
M
Kui
Hong
H
Michio
Namikoshi
N
Nai-Li
Wang
W
Xin-Sheng
Yao
Y
D000818:Animals; D005658:Fungi / Q000737:chemistry*; D018942:Macrolides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009281:Naphthalenes / Q000737:chemistry*; D011161:Porifera / Q000382:microbiology; D013237:Stereoisomerism
D018942:Macrolides; D009281:Naphthalenes