Extramedullary peritoneal hematopoiesis combined with tuberculosis in a patient with primary myelofibrosis.
Primary myelofibrosis (PMF) is a myeloproliferative disorder characterized by bone marrow fibrosis or dysmegakaryocytes, extramedullary hematopoiesis, and the presence of JAK2 mutations. We present a 73-year-old man with PMF that had a fulminant clinical course. Peritoneal extramedullary hematopoiesis combined with tuberculosis was found 4 months after the diagnosis. This combination of complications has not been previously reported. These events were followed by rapid leukemic transformation and the patient's death.
Kim
Su-Jung
SJ
Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea.
Lee
Yenna
Y
Kim
Sung-Han
SH
Kim
Haeryoung
H
Park
Kyoung-Un
KU
Bang
Soo-Mee
SM
Lee
Jong-Seok
JS
D000368:Aged; D001201:Ascites / Q000000981:diagnostic imaging; D017809:Fatal Outcome; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics; D008297:Male; D009154:Mutation; D010537:Peritoneum / Q000473:pathology*; D014395:Peritonitis, Tuberculous / Q000150:complications* / Q000000981:diagnostic imaging; D055728:Primary Myelofibrosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography
D053614:Janus Kinase 2