Diversity in gold- and silver-catalyzed cycloisomerization of epoxide-alkyne functionalities.
We report Au(I)- and Ag(I)-catalyzed cycloisomerizations of epoxide-alkyne functionalities in both aromatic and nonaromatic systems, leading to diversified carbocyclic and heterocyclic frameworks with high chemoselectivities. The use of such cycloisomerizations is reflected by a facile access to the cores of natural pallidol and gibberic acid.
Department of Chemistry, National Tsing-Hua University, Hsinchu, Taiwan, ROC.
Guan-You
GY
Lin
Chia-Wen
CW
Li
Siao-Hua
SH
Hung
Rai-Shung
RS
Liu