Cardiac gene regulatory networks in Drosophila.
The Drosophila system has proven a powerful tool to help unlock the regulatory processes that occur during specification and differentiation of the embryonic heart. In this review, we focus upon a temporal analysis of the molecular events that result in heart formation in Drosophila, with a particular emphasis upon how genomic and other cutting-edge approaches are being brought to bear upon the subject. We anticipate that systems-level approaches will contribute greatly to our comprehension of heart development and disease in the animal kingdom.
Department of Biology, University of New Mexico, Albuquerque, NM 87131-0001, USA.
Anton L
AL
Bryantsev
Richard M
RM
Cripps
D000818:Animals; D004330:Drosophila / Q000196:embryology* / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000378:metabolism*; D053263:Gene Regulatory Networks; D006321:Heart / Q000502:physiology*