[Experimental research on application of hydrodynamic acoustic generator in extraction of Chinese medicine].
OBJECTIVE
To study the hydrodynamic ultrasonic energy extraction technique for Chinese Medicine.


METHODS
The content of baicalin in Radix Scutellariae extracts and total flavones in Folium Ginkgo extracts were as indexes respectively and measured by high performance liquid chromatography. We investigated the hydrodynamic ultrasonic energy extraction process for the extraction of Radix Scutellariae and Folium Ginkgo respectively, and compared with refluxing method, decoction and ultrasonic extraction. With the content of the extracts as indexes, Compound prescriptions of Traditional Chinese Medicine were extracted by the hydrodynamic ultrasonic extraction and decoction extraction.


RESULTS
The content of baicalin of hydrodynamic ultrasonic energy extracts was significant higher than other extracts. The content of Ginkgo leaves flavones in hydrodynamic ultrasonic energy extracts and ultrasonic extracts had no significant difference. Compared with decocting extracts, hydrodynamic ultrasonic energy extracts of TCM compound prescriptions content was higher greatly.


CONCLUSIONS
The hydrodynamic ultrasonic energy extraction process showed higher extraction rate of baicalin of radix scutellariae than traditional extraction methods. And it was beneficial to the dissolution of water-soluble constituents in compound prescriptions of TCM. The content of Ginkgo leaves flavones in the hydrodynamic ultrasonic energy extracts and ultrasonic extracts had no obvious difference.
Di
Wang
W
School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China. wangdi20022008@tom.com
Guan-huai
Zou
Hai-yan
HY
Yu
Ping
P
Xu
Yang
Y
Zhang
Hong-yue
HY
D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D047309:Flavones / Q000032:analysis / Q000737:chemistry; D005419:Flavonoids / Q000032:analysis / Q000302:isolation & purification; D020441:Ginkgo biloba / Q000737:chemistry; D012015:Reference Standards; D031363:Scutellaria / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D014465:Ultrasonics
D004365:Drugs, Chinese Herbal; D047309:Flavones; D005419:Flavonoids; C038044:baicalin