Dissecting cellulitis of the scalp treated with rifampicin and isotretinoin: case reports.
Dissecting cellulitis of the scalp, or perifolliculitis capitis abscedens et suffodiens, is an uncommon chronic suppurative disease of the scalp manifested by follicular and perifollicular inflammatory nodules that suppurate and undermine, forming intercommunicating sinuses, and leading to scarring alopecia. Treatment generally fails to obtain a permanently successful result; thus, many therapeutic options have been proposed. We report 4 cases of dissecting cellulitis of the scalp successfully treated with oral rifampicin and oral isotretinoin. To our knowledge, this is the first report of oral rifampicin used concomitantly with oral isotretinoin in this disease entity. We also present a brief review of the literature on the topic.
Department of Dermatology, University of Athens, Andreas Sygros Hospital, Greece.
Sofia
S
Georgala
Chrysovalantis
C
Korfitis
Dikaia
D
Ioannidou
Theodosis
T
Alestas
Georgios
G
Kylafis
Caterina
C
Georgala
D000284:Administration, Oral; D000328:Adult; D002481:Cellulitis / Q000175:diagnosis* / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use*; D012536:Scalp Dermatoses / Q000175:diagnosis* / Q000188:drug therapy*
D003879:Dermatologic Agents; D004791:Enzyme Inhibitors; D015474:Isotretinoin; D012293:Rifampin