Treatment of lentigo maligna with total circumferential margin control using vertical and horizontal permanent sections: a retrospective study.
This retrospective study assesses the long-term cure rate for the treatment of lentigo maligna using total circumferential margin control with vertical and horizontal permanent sections using life-table analysis. A cohort of 31 patients in Sydney with lentigo maligna treated with total circumferential margin control with vertical and horizontal permanent sections over a 6-year period were followed up. Follow up to determine recurrence was obtained by direct examination, by contact with the referring dermatologist, general practitioner, or by telephone interview with the patient's relative if the patient was deceased. Following our total circumferential margin control technique, of the 16 primary tumours, only one recurred (a cure rate of 94%). Of the 15 recurrent tumours, two had recurred. The mean follow-up time in this study was 42 months (range 12-89 months). Kaplan-Meier analysis estimated that at 5 years, 87% of patients would be free from disease (95% confidence interval 70-100%). Seventy-five per cent of the population can be expected to be disease-free for 6 years (lower 95% confidence limit 4 years). We describe the use of total circumferential margin control with vertical and horizontal permanent sections for the treatment of lentigo maligna that we believe is simple, effective and reproducible.
Department of Dermatology, Royal North Shore Hospital, Pacific Highway, St Leonards, New South Wales, Australia. mick155@hotmail.com
Michael R
MR
Lee
William J
WJ
Ryman
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000556:Ambulatory Surgical Procedures / Q000295:instrumentation / Q000379:methods; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000601:surgery*; D016896:Treatment Outcome