Dicobalt hexacarbonyl complexes of alkynyl imines in a sequential Staudinger/Pauson-Khand process. A route to new fused tricyclic beta-lactams.
Dicobalt hexacarbonyl complexes of alkynyl imines were allowed to react with ketenes via Staudinger reaction. Sequential [2 + 2] cycloaddition/Pauson-Khand reaction led to structurally new fused-tricyclic beta-lactams and fused-azabicyclic cyclopentenones. Chemoselectivity, scope, and limitation of the process were investigated.
Olier
Clarisse
C
Laboratoire de Chimie Moléculaire Organique, LCP UMR 6264, boite 562, Université Paul Cézanne, Faculté des Sciences St. Jérôme, Avenue Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France.
Azzi
Nadia
N
Gil
Gérard
G
Gastaldi
Stéphane
S
Bertrand
Michèle P
MP