A feasibility study of methodology for recruitment and for comparative testing of ciliary function in Hawaiians and Caucasians.
Native Hawaiians have higher lung cancer incidence and mortality than other ethnic groups, even after controlling for smoking. Could reduced mucociliary clearance, suspected in Polynesians, play a role? In this pilot study of 9 Hawaiian and 8 Caucasian men, mean velocities were faster although not statistically significant in Caucasians. This pilot also generated recommendations on subject recruitment, measures, and data analysis for future studies.
Gellert
Kapuaola S
KS
'Imi Hale Native Hawaiian Cancer Network, Papa Ola Lokahi, Honolulu, HI 96813, USA. kapuaola@gmail.com
Choi
Dongseok
D
Coel
Marc
M
Braun
Kathryn L
KL
D000328:Adult; D002923:Cilia / Q000502:physiology*; D005006:Ethnicity; D005240:Feasibility Studies; D006254:Hawaii; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*; D044468:Native Hawaiian or Pacific Islander; D018579:Patient Selection; D012106:Research; D044465:White People