Real-time PCR assays for high-throughput human platelet antigen typing.
Most human platelet alloantigen (HPA) systems comprise biallelic single nucleotide polymorphisms in genes encoding major membrane glycoproteins. Genotyping for these systems is required in the investigation of patients with suspected HPA antibodies and for the provision of compatible blood products from HPA-typed donor panel populations.
Department of Platelet Immunology, NHS Blood and Transplant, Cambridge, UK.
Simon E
SE
McBride
D016824:Antigens, Human Platelet / Q000235:genetics*; D001782:Blood Donors; D046148:Donor Selection / Q000379:methods*; D006801:Humans; D016133:Polymerase Chain Reaction / Q000295:instrumentation / Q000379:methods*; D020641:Polymorphism, Single Nucleotide
D016824:Antigens, Human Platelet