Psychobiology of mindfulness.
There is controversy about whether mindfulness-based approaches to psychotherapy represent a new wave of cognitive-behavioral therapy or a core process in all psychotherapies. One way of conceptualizing mindfulness is in terms of emotion regulation; mindfulness is a strategy aimed at opposing suppression and avoidance. Dispositional mindfulness has been associated with greater activation in prefrontal cortex and greater deactivation of amygdala during affect labeling. A number of rigorous studies of mindfulness-based cognitive therapy for depression have been positive. However, much remains to be discovered about the underlying mechanisms of and clinical indications for mindfulness-based approaches.
Department of Psychiatry and Mental Health at the University of Cape Town, Cape Town, South Africa.
Dan J
DJ
Stein
Victoria
V
Ives-Deliperi
Kevin G F
KG
Thomas
D000328:Adult; D000679:Amygdala / Q000503:physiopathology; D001288:Attention / Q000502:physiology*; D001364:Awareness / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003866:Depressive Disorder / Q000503:physiopathology / Q000628:therapy; D004644:Emotions / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D017397:Prefrontal Cortex / Q000503:physiopathology*; D011613:Psychotherapy / Q000379:methods*; D013850:Thinking / Q000502:physiology*