Effective treatment with topical cyclosporine of a child with steroid-dependent interstitial keratitis.
OBJECTIVE
To report a case of steroid-dependent idiopathic interstitial keratitis in a child successfullytreated with topical cyclosporine 2% drops.


METHODS
Case report.


RESULTS
The authors describe a case of a 6-year-old boy with a history of recurrent idiopathic bilateral interstitial keratitis. The patient had recurrent episodes of corneal inflammation that became more frequent and severe during the follow-up, and caused severe corneal opacities and visual loss. Long-term treatment with topical corticosteroid was required to avoid corneal scarring that eventually caused secondary elevation of intraocular pressure. Topical cyclosporine 2% was therefore introduced as a steroid sparing agent totreat the keratitis. The treatment was continued for 1 year and the patient achieved a complete remission of corneal inflammation with resolution of corneal scarring and normalization of intraocular pressure.


CONCLUSIONS
In this child with recurrent episodes of interstitial keratitis, topical cyclosporine 2% has been shown to be a safe and effective alternative for treating corneal inflammation.
Department of Ophthalmology and Visual Sciences, San Raffaele Scientific Institute, Milano - Italy. miserocchi.elisabetta@hsr.it
E
E
Miserocchi
G
G
Modorati
P
P
Rama
D000287:Administration, Topical; D002648:Child; D003319:Corneal Stroma / Q000187:drug effects*; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007429:Intraocular Pressure; D007634:Keratitis / Q000188:drug therapy*; D008297:Male; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D012008:Recurrence
D007166:Immunosuppressive Agents; D016572:Cyclosporine; C009935:prednisolone acetate; D011239:Prednisolone