[A rat model for cochlear implant research].
OBJECTIVE
To introduce a rat model for use in cochlear implant related research.


METHODS
Five deafened Hooded-Wistar rats were implanted with a scala tympani electrode array using a new surgical method. Electrically evoked brainstem responses (EABRs) using bipolar stimulation were recorded and cochlear history was assessed.


RESULTS
Electrically evoked brainstem responses with normal configuration confirmed the functional status of the cochlear implantation. There was no evidence of severe insertion-induced damage of intra-cochlear structure.


CONCLUSIONS
The surgical method established in the rat model is a safe and effective procedure for acute or chronic cochlear implantation.
Department of Otolaryngology, 1st Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China. luweimd@hotmail.com
Wei
W
Lu
Jin
J
Xu
R K
RK
Shepherd
D000818:Animals; D019929:Cochlear Implantation / Q000379:methods*; D003054:Cochlear Implants; D016057:Evoked Potentials, Auditory, Brain Stem; D008297:Male; D023421:Models, Animal; D051381:Rats; D017208:Rats, Wistar