International comparison of clinical, bovine, and environmental Escherichia coli O157 isolates on the basis of Shiga toxin-encoding bacteriophage insertion site genotypes.
Escherichia coli O157:H7 genotypes in the bovine reservoir may differ in virulence. The proportion of clinical genotypes among cattle isolates was weakly (P = 0.054) related to the international incidence of E. coli O157:H7-associated hemolytic-uremic syndrome, varied among clinical isolates internationally, and also differed along the putative cattle-hamburger-clinical case transmission chain.
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA.
Joshua H
JH
Whitworth
Narelle
N
Fegan
Jasmin
J
Keller
Kari S
KS
Gobius
James L
JL
Bono
Douglas R
DR
Call
Dale D
DD
Hancock
Thomas E
TE
Besser
D000818:Animals; D001435:Bacteriophages / Q000235:genetics*; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D004783:Environmental Microbiology; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D019453:Escherichia coli O157 / Q000235:genetics* / Q000302:isolation & purification* / Q000821:virology; D005838:Genotype; D006463:Hemolytic-Uremic Syndrome / Q000382:microbiology*; D006801:Humans; D017720:Molecular Epidemiology; D011110:Polymorphism, Genetic; D039002:Prophages / Q000235:genetics*; D022603:Shiga Toxins / Q000096:biosynthesis
D022603:Shiga Toxins