Catastrophic antiphospholipid (Asherson's) syndrome.
Catastrophic antiphospholipid syndrome is characterized by multiple organ involvement developing over a very short period of time, histopathological evidence of multiple small vessel occlusions, and laboratory confirmation of the presence of antiphospholipid antibodies. Knowledge of its treatment is vital as the outcome can be lethal.
Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain.
Ricard
R
Cervera
Ronald A
RA
Asherson
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D000925:Anticoagulants / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000145:classification / Q000150:complications / Q000188:drug therapy*; D002388:Catastrophic Illness; D002648:Child; D042241:Early Diagnosis; D005260:Female; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000517:prevention & control*; D011379:Prognosis; D016896:Treatment Outcome; D055815:Young Adult
D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D007136:Immunoglobulins; D006493:Heparin