Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients.
We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration.
Isakov
I V
IV
Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Krasnoyarsk.
Kurtasova
L M
LM
D015703:Antigens, CD / Q000096:biosynthesis*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000096:biosynthesis*; D018414:CD8-Positive T-Lymphocytes / Q000378:metabolism*; D015658:HIV Infections / Q000097:blood / Q000276:immunology*; D006801:Humans; D037181:Lectins, C-Type; D000099192:CD69 Antigens
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D037181:Lectins, C-Type; D000099192:CD69 Antigens