Ruthenium hydride-catalyzed addition of aldehydes to dienes leading to beta,gamma-unsaturated ketones.
An efficient cross-addition reaction of dienes with aldehydes was developed by using RuHCl(CO)(PPh3)3 as a catalyst to give a wide variety of beta,gamma-unsaturated ketones, where a pi-allylruthenium species, derived from hydroruthenation of diene, may be involved as a key intermediate.
Omura
Sohei
S
Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
Fukuyama
Takahide
T
Horiguchi
Jiro
J
Murakami
Yuji
Y
Ryu
Ilhyong
I
D000447:Aldehydes / Q000737:chemistry*; D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D000466:Alkadienes; D007659:Ketones; D009942:Organometallic Compounds; D012428:Ruthenium; D006859:Hydrogen