[Artificial polysaccharide in contaminated heparin. Acute hypersensitivity reactions explained--but how could it happen?].
Lindahl
Ulf
U
Uppsala universitet. ulf.lindahl@imbim.uu.se
D000707:Anaphylaxis / Q000139:chemically induced*; D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects* / Q000032:analysis; D002809:Chondroitin Sulfates / Q000009:adverse effects* / Q000032:analysis / Q000737:chemistry; D003167:Complement Activation / Q000187:drug effects; D004340:Drug Contamination / Q000517:prevention & control; D006493:Heparin / Q000009:adverse effects* / Q000032:analysis / Q000737:chemistry; D006801:Humans; D007610:Kallikreins / Q000378:metabolism; D013552:Swine
D000925:Anticoagulants; D006493:Heparin; D002809:Chondroitin Sulfates; D007610:Kallikreins
Artificiell polysackarid gav kontaminerat heparin. Akuta överkänslighetsreaktioner får sin förklaring--men hur kunde det hända?