Relevance of osteoproliferation as an outcome parameter in ankylosing spondylitis.
In light of the impressive efficacy of tumor necrosis factor blockers in the treatment of ankylosing spondylitis, particularly in patients with short disease duration, defining outcome parameters to monitor the structural damage of the disease has become more pertinent. In this Viewpoint the authors explore the relevance of osteoproliferation amongst other outcome parameters.
Appel
Heiner
H
Department of Medicine at the Charité Hospital Benjamin Franklin, Berlin, Germany.
Rudwaleit
Martin
M
Sieper
Joachim
J
D006801:Humans; D010012:Osteogenesis / Q000187:drug effects; D013167:Spondylitis, Ankylosing / Q000188:drug therapy / Q000503:physiopathology*; D000079424:Tumor Necrosis Factor Inhibitors
D000079424:Tumor Necrosis Factor Inhibitors