Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction.
D000818:Animals; D015153:Blotting, Western; D002478:Cells, Cultured; D002864:Chromogranins / Q000378:metabolism; D017077:Culture Media, Conditioned / Q000032:analysis / Q000494:pharmacology*; D015180:Electrophoresis, Gel, Two-Dimensional; D005947:Glucose / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism*; D013058:Mass Spectrometry; D051379:Mice; D010641:Phenotype; D011228:Prealbumin / Q000378:metabolism; D020543:Proteome / Q000032:analysis*
D002864:Chromogranins; D017077:Culture Media, Conditioned; D007328:Insulin; D011228:Prealbumin; D020543:Proteome; C506167:secretogranin III; D005947:Glucose