Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats.
D000818:Animals; D005355:Fibrosis; D006439:Hemodynamics; D007249:Inflammation / Q000188:drug therapy / Q000517:prevention & control*; D007674:Kidney Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control*; D008297:Male; D019331:NG-Nitroarginine Methyl Ester / Q000009:adverse effects*; D009569:Nitric Oxide / Q000378:metabolism; D053495:Osteopontin / Q000032:analysis / Q000235:genetics; D020011:Protective Agents; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D017208:Rats, Wistar; D018161:Receptors, Mineralocorticoid / Q000502:physiology; D013148:Spironolactone / Q000494:pharmacology
D020011:Protective Agents; D012333:RNA, Messenger; D018161:Receptors, Mineralocorticoid; D053495:Osteopontin; D013148:Spironolactone; D009569:Nitric Oxide; D019331:NG-Nitroarginine Methyl Ester