Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.
D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology; D005786:Gene Expression Regulation; D016678:Genome / Q000235:genetics; D006367:HeLa Cells; D006801:Humans; D056921:Nuclear Receptor Coactivator 3; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D011485:Protein Binding; D054645:Protein Phosphatase 1 / Q000378:metabolism; D054648:Protein Phosphatase 2 / Q000378:metabolism; D034741:RNA, Small Interfering / Q000378:metabolism; D011960:Receptors, Estrogen / Q000378:metabolism; D015398:Signal Transduction; D013816:Thermodynamics; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic
D010750:Phosphoproteins; D034741:RNA, Small Interfering; D011960:Receptors, Estrogen; D014157:Transcription Factors; D010768:Phosphoserine; D056921:Nuclear Receptor Coactivator 3; C496428:PDXP protein, human; D010749:Phosphoprotein Phosphatases; D054645:Protein Phosphatase 1; D054648:Protein Phosphatase 2; D010744:Phosphoric Monoester Hydrolases; D046988:Proteasome Endopeptidase Complex