PGE2 signal via EP2 receptors evoked by a selective agonist enhances regeneration of injured articular cartilage.
D000818:Animals; D002097:C-Reactive Protein / Q000378:metabolism; D002358:Cartilage, Articular / Q000187:drug effects / Q000293:injuries* / Q000473:pathology / Q000502:physiology; D049109:Cell Proliferation / Q000187:drug effects; D015232:Dinoprostone / Q000502:physiology*; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical / Q000379:methods; D019278:Matrix Metalloproteinase 3 / Q000378:metabolism; D011817:Rabbits; D018078:Receptors, Prostaglandin E / Q000819:agonists / Q000502:physiology*; D058307:Receptors, Prostaglandin E, EP2 Subtype; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D013582:Synovial Fluid / Q000378:metabolism; D013583:Synovial Membrane / Q000187:drug effects / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D018078:Receptors, Prostaglandin E; D058307:Receptors, Prostaglandin E, EP2 Subtype; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein; D019278:Matrix Metalloproteinase 3; D015232:Dinoprostone