Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism.
D000228:Adenine Phosphoribosyltransferase / Q000235:genetics; D052242:Adiponectin / Q000378:metabolism; D000818:Animals; D006528:Carcinoma, Hepatocellular; D045744:Cell Line, Tumor; D004789:Enzyme Activation / Q000187:drug effects; D005632:Fructose / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism; D020738:Leptin / Q000502:physiology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008113:Liver Neoplasms; D008297:Male; D010750:Phosphoproteins / Q000378:metabolism*; D010768:Phosphoserine / Q000378:metabolism; D010769:Phosphothreonine / Q000378:metabolism; D016133:Polymerase Chain Reaction; D051381:Rats; D017207:Rats, Sprague-Dawley; D015398:Signal Transduction / Q000187:drug effects; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins / Q000037:antagonists & inhibitors / Q000502:physiology*
D052242:Adiponectin; D020738:Leptin; D010750:Phosphoproteins; C491410:Socs3 protein, rat; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins; D010769:Phosphothreonine; D010768:Phosphoserine; D005632:Fructose; D000228:Adenine Phosphoribosyltransferase; D005947:Glucose