Nicotine promotes mammary tumor migration via a signaling cascade involving protein kinase C and CDC42.
D000818:Animals; D001940:Breast / Q000187:drug effects / Q000201:enzymology; D001943:Breast Neoplasms / Q000473:pathology*; D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D051379:Mice; D009538:Nicotine / Q000633:toxicity*; D051571:Protein Kinase C-alpha / Q000502:physiology*; D015398:Signal Transduction / Q000187:drug effects*; D020764:cdc42 GTP-Binding Protein / Q000502:physiology*
D009538:Nicotine; D051571:Protein Kinase C-alpha; D020764:cdc42 GTP-Binding Protein