A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain.
D001741:Black or African American / Q000235:genetics; D019973:Alcohol-Related Disorders / Q000235:genetics; D001921:Brain / Q000378:metabolism*; D019970:Cocaine-Related Disorders / Q000235:genetics*; D004745:Enkephalins / Q000235:genetics* / Q000378:metabolism; D015870:Gene Expression; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006239:Haplotypes; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D011498:Protein Precursors / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D044465:White People / Q000235:genetics
D004745:Enkephalins; D011498:Protein Precursors; D012333:RNA, Messenger; C033660:preproenkephalin