BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development.
D000818:Animals; D054087:Atrial Septum / Q000166:cytology / Q000196:embryology*; D055415:Bone Morphogenetic Protein 4 / Q000096:biosynthesis* / Q000235:genetics; D054089:Endocardial Cushions / Q000166:cytology / Q000196:embryology*; D006346:Heart Septum / Q000166:cytology / Q000196:embryology*; D006351:Heart Valves / Q000166:cytology / Q000378:metabolism*; D008648:Mesoderm / Q000166:cytology / Q000196:embryology; D051379:Mice; D018345:Mice, Knockout; D009432:Neural Crest / Q000166:cytology / Q000196:embryology
C525810:Bmp4 protein, mouse; D055415:Bone Morphogenetic Protein 4