Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis.
D051700:Activating Transcription Factor 3 / Q000502:physiology*; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D017209:Apoptosis; D018925:Chemokines; D015536:Down-Regulation; D004721:Endoplasmic Reticulum / Q000378:metabolism; D015316:Genetic Therapy; D006367:HeLa Cells; D006801:Humans; D051798:Inhibitor of Differentiation Protein 1 / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000502:physiology*; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics / Q000502:physiology*; D048031:JNK Mitogen-Activated Protein Kinases / Q000502:physiology; D051379:Mice; D008807:Mice, Inbred BALB C; D009101:Multiple Myeloma / Q000378:metabolism / Q000401:mortality / Q000628:therapy; D016328:NF-kappa B / Q000502:physiology; D010766:Phosphorylation; D011401:Promoter Regions, Genetic; D051785:Smad Proteins / Q000502:physiology*
C490449:ATF3 protein, human; D051700:Activating Transcription Factor 3; D048868:Adaptor Proteins, Signal Transducing; C103002:Atf3 protein, mouse; D018925:Chemokines; C498624:DKK3 protein, human; C405061:Dkk3 protein, mouse; C497453:ID1 protein, human; C497455:Idb1 protein, mouse; D051798:Inhibitor of Differentiation Protein 1; D036341:Intercellular Signaling Peptides and Proteins; D016328:NF-kappa B; D051785:Smad Proteins; D048031:JNK Mitogen-Activated Protein Kinases