Peptide P5 (residues 628-683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection.
D002460:Cell Line; D002478:Cells, Cultured; D002942:Circular Dichroism; D015700:HIV Envelope Protein gp41 / Q000037:antagonists & inhibitors*; D023581:HIV Fusion Inhibitors / Q000494:pharmacology*; D015497:HIV-1 / Q000502:physiology*; D006801:Humans; D010455:Peptides / Q000494:pharmacology*; D017433:Protein Structure, Secondary; D053585:Virus Attachment
D015700:HIV Envelope Protein gp41; D023581:HIV Fusion Inhibitors; D010455:Peptides; C514787:gp41 protein, Human immunodeficiency virus 1