Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes.
D000818:Animals; D002528:Cerebellar Neoplasms / Q000235:genetics* / Q000378:metabolism*; D015254:DNA Modification Methylases / Q000378:metabolism; D045643:DNA Repair Enzymes / Q000378:metabolism; D004847:Epithelial Cells / Q000378:metabolism; D006367:HeLa Cells; D053823:Hedgehog Proteins / Q000378:metabolism*; D006801:Humans; D017874:Immediate-Early Proteins / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008527:Medulloblastoma / Q000235:genetics* / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D051381:Rats; D020813:Receptor, trkB / Q000378:metabolism; D019718:Receptors, CXCR4 / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism / Q000502:physiology*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D025521:Tumor Suppressor Proteins / Q000378:metabolism; D000071676:Zinc Finger Protein GLI1; D000099184:Serum-Glucocorticoid Regulated Kinases
D015254:DNA Modification Methylases; D045643:DNA Repair Enzymes; D053823:Hedgehog Proteins; D017874:Immediate-Early Proteins; D017346:Protein Serine-Threonine Kinases; D020813:Receptor, trkB; D019718:Receptors, CXCR4; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; D000071676:Zinc Finger Protein GLI1; D000099184:Serum-Glucocorticoid Regulated Kinases; C527276:CXCR4 protein, human; C400551:GLI1 protein, human; C515491:MGMT protein, human