Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo development.
D002118:Calcium / Q000378:metabolism*; D047108:Embryonic Development / Q000235:genetics*; D006801:Humans; D008297:Male; D054801:Phosphoinositide Phospholipase C / Q000235:genetics* / Q000378:metabolism; D013094:Spermatozoa / Q000378:metabolism / Q000502:physiology*
C499235:PLCZ1 protein, human; D054801:Phosphoinositide Phospholipase C; D002118:Calcium