Increased diabetes development and decreased function of CD4+CD25+ Treg in the absence of a functional DAP12 adaptor protein.
D048868:Adaptor Proteins, Signal Transducing / Q000502:physiology*; D000818:Animals; D039521:CD11c Antigen / Q000032:analysis; D003713:Dendritic Cells / Q000502:physiology; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology*; D007515:Islets of Langerhans / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008213:Lymphocyte Activation; D051379:Mice; D016688:Mice, Inbred NOD; D011948:Receptors, Antigen, T-Cell / Q000502:physiology; D013601:T-Lymphocytes / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000502:physiology*
D048868:Adaptor Proteins, Signal Transducing; D039521:CD11c Antigen; D011948:Receptors, Antigen, T-Cell; C484963:Tyrobp protein, mouse