title: Kappa-opioid system regulates the long-lasting behavioral adaptations induced by early-life exposure to methylphenidate.
mesh_terms: D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer / Q000008:administration & dosage; D000818:Animals; D001007:Anxiety / Q000503:physiopathology; D001522:Behavior, Animal / Q000187:drug effects*; D000697:Central Nervous System Stimulants / Q000008:administration & dosage; D003042:Cocaine; D003213:Conditioning, Psychological / Q000187:drug effects / Q000502:physiology; D005518:Food Preferences / Q000187:drug effects / Q000502:physiology; D008297:Male; D008774:Methylphenidate / Q000008:administration & dosage*; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology; D009271:Naltrexone / Q000008:administration & dosage / Q000031:analogs & derivatives; D011619:Psychotropic Drugs / Q000008:administration & dosage; D051381:Rats; D017207:Rats, Sprague-Dawley; D017473:Receptors, Opioid, kappa / Q000819:agonists / Q000378:metabolism*; D013315:Stress, Psychological / Q000503:physiopathology
chemical_list: D000697:Central Nervous System Stimulants; D011619:Psychotropic Drugs; D017473:Receptors, Opioid, kappa; D008774:Methylphenidate; C051844:norbinaltorphimine; D009271:Naltrexone; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D003042:Cocaine