The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents.
D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D000077237:Arsenic Trioxide; D001152:Arsenicals / Q000494:pharmacology; D001241:Aspirin / Q000031:analogs & derivatives / Q000494:pharmacology; D006052:Gold Sodium Thiomalate / Q000494:pharmacology; D019073:HT29 Cells; D006801:Humans; D048848:MAP Kinase Kinase Kinase 5 / Q000502:physiology; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D016328:NF-kappa B / Q000378:metabolism; D020030:Nitric Oxide Donors / Q000494:pharmacology; D010755:Organophosphates / Q000494:pharmacology; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010087:Oxides / Q000494:pharmacology; D026361:Reactive Nitrogen Species / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D013880:Thioredoxin-Disulfide Reductase / Q000037:antagonists & inhibitors; D013879:Thioredoxins / Q000502:physiology*
D000970:Antineoplastic Agents; D001152:Arsenicals; D016328:NF-kappa B; D020030:Nitric Oxide Donors; D010755:Organophosphates; D010087:Oxides; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; C527365:phosphoaspirin; D006052:Gold Sodium Thiomalate; D013879:Thioredoxins; D013880:Thioredoxin-Disulfide Reductase; D020928:Mitogen-Activated Protein Kinases; D048848:MAP Kinase Kinase Kinase 5; C482858:MAP3K5 protein, human; D001241:Aspirin; D000077237:Arsenic Trioxide