TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta.
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002460:Cell Line; D004789:Enzyme Activation / Q000187:drug effects; D004848:Epithelium / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D048031:JNK Mitogen-Activated Protein Kinases / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism; D020930:MAP Kinase Kinase Kinases / Q000378:metabolism; D008648:Mesoderm / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D011485:Protein Binding / Q000187:drug effects; D018125:Receptors, Transforming Growth Factor beta / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D051785:Smad Proteins / Q000378:metabolism; D048029:TNF Receptor-Associated Factor 6 / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000494:pharmacology*; D054875:Ubiquitination / Q000187:drug effects; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism*; D000099151:MAP Kinase Kinase Kinase 7
D048031:JNK Mitogen-Activated Protein Kinases; D008239:Lysine; D020930:MAP Kinase Kinase Kinases; D018125:Receptors, Transforming Growth Factor beta; D051785:Smad Proteins; D048029:TNF Receptor-Associated Factor 6; D016212:Transforming Growth Factor beta; D048051:p38 Mitogen-Activated Protein Kinases; D000099151:MAP Kinase Kinase Kinase 7