BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway.
D000818:Animals; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics / Q000378:metabolism*; D050882:CREB-Binding Protein / Q000235:genetics / Q000378:metabolism; D051786:Cyclic AMP Response Element Modulator / Q000235:genetics / Q000378:metabolism; D004827:Epilepsy / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D053612:Janus Kinases / Q000235:genetics / Q000378:metabolism*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D011963:Receptors, GABA-A / Q000096:biosynthesis* / Q000235:genetics; D050796:STAT3 Transcription Factor / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics; D013570:Synaptic Membranes / Q000235:genetics / Q000378:metabolism
D019208:Brain-Derived Neurotrophic Factor; C497410:CREM protein, human; C497412:Crem protein, rat; D011963:Receptors, GABA-A; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; C494088:Stat3 protein, rat; D051786:Cyclic AMP Response Element Modulator; D050882:CREB-Binding Protein; C494363:CREBBP protein, human; C494365:Crebbp protein, rat; D053612:Janus Kinases