Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta.
D015703:Antigens, CD / Q000502:physiology; D001402:B-Lymphocytes / Q000276:immunology*; D060908:CTLA-4 Antigen; D002460:Cell Line; D051858:Forkhead Transcription Factors / Q000032:analysis / Q000502:physiology; D053450:Glucocorticoid-Induced TNFR-Related Protein; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis*; D007156:Immunologic Memory; D016753:Interleukin-10 / Q000502:physiology*; D017475:Receptors, Nerve Growth Factor / Q000502:physiology*; D018124:Receptors, Tumor Necrosis Factor / Q000502:physiology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D016212:Transforming Growth Factor beta / Q000502:physiology*; D048069:Tumor Necrosis Factors / Q000502:physiology*
D015703:Antigens, CD; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C418974:FOXP3 protein, human; D051858:Forkhead Transcription Factors; D053450:Glucocorticoid-Induced TNFR-Related Protein; D007074:Immunoglobulin G; D017475:Receptors, Nerve Growth Factor; D018124:Receptors, Tumor Necrosis Factor; C491405:TNFRSF18 protein, human; C478967:TNFSF18 protein, human; D016212:Transforming Growth Factor beta; D048069:Tumor Necrosis Factors; D016753:Interleukin-10