Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer.
D000818:Animals; D001943:Breast Neoplasms / Q000737:chemistry / Q000209:etiology* / Q000473:pathology; D045744:Cell Line, Tumor; D005260:Female; D018734:Genes, erbB-2; D006801:Humans; D008562:Membrane Glycoproteins / Q000032:analysis / Q000037:antagonists & inhibitors / Q000502:physiology*; D051379:Mice; D008822:Mice, Transgenic; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000502:physiology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis / Q000502:physiology*; D015398:Signal Transduction
D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; C484445:LRIG1 protein, human; C101671:Lrig1 protein, mouse; C508053:ERBB2 protein, human; C524056:Erbb2 protein, mouse