Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: a factor contributing to airway fibrosis.
D051698:Activating Transcription Factor 2 / Q000378:metabolism; D001647:Bile Acids and Salts / Q000494:pharmacology*; D015153:Blotting, Western; D001980:Bronchi / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D002478:Cells, Cultured; D055513:Connective Tissue Growth Factor / Q000096:biosynthesis* / Q000187:drug effects / Q000235:genetics; D003907:Dexamethasone / Q000494:pharmacology; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004797:Enzyme-Linked Immunosorbent Assay; D005355:Fibrosis / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D015870:Gene Expression; D005938:Glucocorticoids / Q000494:pharmacology; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D010766:Phosphorylation; D011725:Pyridines / Q000494:pharmacology; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics*; D020545:Respiratory Mucosa / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D053773:Transforming Growth Factor beta1 / Q000096:biosynthesis / Q000187:drug effects; D048051:p38 Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*
D051698:Activating Transcription Factor 2; D001647:Bile Acids and Salts; C526317:CCN2 protein, human; D004791:Enzyme Inhibitors; D005938:Glucocorticoids; D007093:Imidazoles; D011725:Pyridines; D012333:RNA, Messenger; D053773:Transforming Growth Factor beta1; D055513:Connective Tissue Growth Factor; D003907:Dexamethasone; D048051:p38 Mitogen-Activated Protein Kinases; C093642:SB 203580