title: Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.
mesh_terms: D015687:Cell Hypoxia; D045744:Cell Line, Tumor; D019070:Cell Lineage; D051272:Glucose Transporter Type 1 / Q000032:analysis; D038362:Glycogen Synthase Kinase 3 / Q000502:physiology; D000071679:Glycogen Synthase Kinase 3 beta; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000032:analysis / Q000378:metabolism*; D008297:Male; D009369:Neoplasms / Q000378:metabolism*; D010766:Phosphorylation; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000037:antagonists & inhibitors / Q000502:physiology*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction; D016159:Tumor Suppressor Protein p53 / Q000502:physiology; D051794:Von Hippel-Lindau Tumor Suppressor Protein / Q000502:physiology; D000099157:Sphingosine Kinase
chemical_list: D051272:Glucose Transporter Type 1; D038362:Glycogen Synthase Kinase 3; D000071679:Glycogen Synthase Kinase 3 beta; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D017853:Phosphotransferases (Alcohol Group Acceptor); D046988:Proteasome Endopeptidase Complex; D051057:Proto-Oncogene Proteins c-akt; D017382:Reactive Oxygen Species; D016159:Tumor Suppressor Protein p53; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D000099157:Sphingosine Kinase; C497442:HIF1A protein, human; C000605506:GSK3B protein, human