Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations.
D000818:Animals; D019610:Cytoprotection / Q000235:genetics*; D004797:Enzyme-Linked Immunosorbent Assay; D004847:Epithelial Cells / Q000378:metabolism*; D007150:Immunohistochemistry; D007908:Lens, Crystalline / Q000378:metabolism* / Q000503:physiopathology / Q000528:radiation effects; D008027:Light / Q000009:adverse effects; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D020933:Neurotrophin 3 / Q000235:genetics* / Q000378:metabolism*; D020419:Photoreceptor Cells, Vertebrate / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics; D012162:Retinal Degeneration / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D019076:Transgenes / Q000235:genetics; D000076202:c-Mer Tyrosine Kinase
D020933:Neurotrophin 3; D011518:Proto-Oncogene Proteins; D012333:RNA, Messenger; C490767:Mertk protein, mouse; D020794:Receptor Protein-Tyrosine Kinases; D000076202:c-Mer Tyrosine Kinase