title: Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells.
mesh_terms: D017209:Apoptosis; D020134:Catalytic Domain; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D002470:Cell Survival / Q000187:drug effects; D019008:Drug Resistance, Neoplasm; D006801:Humans; D007527:Isoenzymes / Q000737:chemistry; D008297:Male; D016566:Organoselenium Compounds / Q000378:metabolism*; D010100:Oxygen / Q000737:chemistry; D011471:Prostatic Neoplasms / Q000201:enzymology* / Q000378:metabolism; D011493:Protein Kinase C / Q000737:chemistry / Q000378:metabolism*; D034741:RNA, Small Interfering / Q000378:metabolism; D012643:Selenium / Q000494:pharmacology*
chemical_list: D007527:Isoenzymes; D016566:Organoselenium Compounds; D034741:RNA, Small Interfering; C008493:methylselenic acid; D011493:Protein Kinase C; D012643:Selenium; D010100:Oxygen