Human protein S inhibits the uptake of AcLDL and expression of SR-A through Mer receptor tyrosine kinase in human macrophages.
D050197:Atherosclerosis / Q000276:immunology / Q000378:metabolism*; D002788:Cholesterol Esters / Q000378:metabolism; D015536:Down-Regulation / Q000187:drug effects / Q000276:immunology; D015870:Gene Expression / Q000187:drug effects / Q000276:immunology; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008264:Macrophages / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D015513:Oncogene Proteins / Q000378:metabolism; D011485:Protein Binding / Q000187:drug effects / Q000276:immunology; D017293:Protein S / Q000378:metabolism* / Q000494:pharmacology; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000378:metabolism*; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics / Q000378:metabolism*; D051117:Scavenger Receptors, Class A / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000187:drug effects / Q000276:immunology; D020298:U937 Cells; D000076202:c-Mer Tyrosine Kinase; D000094963:Axl Receptor Tyrosine Kinase
D002788:Cholesterol Esters; D008077:Lipoproteins, LDL; C495139:MSR1 protein, human; D015513:Oncogene Proteins; D017293:Protein S; D011518:Proto-Oncogene Proteins; D051117:Scavenger Receptors, Class A; C032629:acetyl-LDL; C097072:MERTK protein, human; D020794:Receptor Protein-Tyrosine Kinases; C084944:TYRO3 protein, human; D000076202:c-Mer Tyrosine Kinase; D000094963:Axl Receptor Tyrosine Kinase; C000722289:AXL protein, human