Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.
D002118:Calcium; D002454:Cell Differentiation; D002843:Chromatin / Q000648:ultrastructure*; D004742:Enhancer Elements, Genetic; D000091344:Filaggrin Proteins; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D006867:Hydrolases / Q000235:genetics*; D015603:Keratinocytes / Q000201:enzymology* / Q000378:metabolism; D009369:Neoplasms / Q000209:etiology; D000080063:Protein-Arginine Deiminase Type 3; D012333:RNA, Messenger / Q000032:analysis; D018808:Transcription Factor AP-1 / Q000502:physiology*; D014158:Transcription, Genetic; D014945:Wound Healing
D002843:Chromatin; C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D012333:RNA, Messenger; D018808:Transcription Factor AP-1; D006867:Hydrolases; D000080063:Protein-Arginine Deiminase Type 3; D002118:Calcium