Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism.
D000818:Animals; D017209:Apoptosis / Q000187:drug effects* / Q000502:physiology; D002478:Cells, Cultured; D018076:DNA, Complementary / Q000235:genetics; D006801:Humans; D020738:Leptin / Q000494:pharmacology*; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D008297:Male; D010587:Phagocytosis / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011924:Rats, Zucker; D014162:Transfection; D020830:rac1 GTP-Binding Protein / Q000235:genetics; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
D018076:DNA, Complementary; D020738:Leptin; D020830:rac1 GTP-Binding Protein; D020741:rho GTP-Binding Proteins