Rational design of antithrombotic peptides to target the von Willebrand factor (vWf)--GPIb integrin interaction.
D001665:Binding Sites; D015195:Drug Design; D055808:Drug Discovery; D005343:Fibrinolytic Agents / Q000737:chemistry*; D016023:Integrins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry*; D010974:Platelet Aggregation; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D011487:Protein Conformation; D014841:von Willebrand Factor / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism
D005343:Fibrinolytic Agents; D016023:Integrins; D010455:Peptides; D019038:Platelet Glycoprotein GPIb-IX Complex; D014841:von Willebrand Factor