Ligation of tumour-produced mucins to CD22 dramatically impairs splenic marginal zone B-cells.
D000230:Adenocarcinoma / Q000276:immunology / Q000378:metabolism*; D000818:Animals; D000955:Antigens, T-Independent / Q000276:immunology / Q000378:metabolism; D001402:B-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D001665:Binding Sites; D016466:CHO Cells; D045744:Cell Line, Tumor; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D008562:Membrane Glycoproteins / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D009077:Mucins / Q000378:metabolism*; D011947:Receptors, Antigen, B-Cell / Q000378:metabolism; D051918:Sialic Acid Binding Ig-like Lectin 2 / Q000276:immunology / Q000378:metabolism*; D015398:Signal Transduction; D013154:Spleen / Q000276:immunology*
D000955:Antigens, T-Independent; D008562:Membrane Glycoproteins; D009077:Mucins; D011947:Receptors, Antigen, B-Cell; D051918:Sialic Acid Binding Ig-like Lectin 2; C016424:epiglycanin protein, mouse