title: [McKittrick- Wheelock syndrome: report of one case].
abstract: Villous colorectal adenomas are common tumors that normally provoke scarce symptomatology. We report a 59 year-old female that was admitted with severe dehydration due to severe diarrhea lasting 10 days and vomiting in the last 48 hours. On rectal palpation a large tumor located 5 cm above the anus was palpated. Colonoscopy confirmed the presence of a villous adenoma that was excised surgically. In this patient, the fluid and electrolyte hypersecretion of the rectal villous adenoma provoked a depletion syndrome with serious hydroelectrolytic alterations, acute renal failure and hypovolemic shock. This syndrome was first described by McKittrick and Wheelock in 1954.
authors.affiliation: Clínica Médica 2, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay. rmila@hc.edu.uy
authors.forename: Rafael
authors.initials: R
authors.lastname: Mila
authors.forename: Sofía
authors.initials: S
authors.lastname: Grille
authors.forename: Marcelo
authors.initials: M
authors.lastname: Laurini
authors.forename: Diego
authors.initials: D
authors.lastname: Lapiedra
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Bagattini
mesh_terms: D018253:Adenoma, Villous / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012007:Rectum / Q000601:surgery; D013577:Syndrome; D014883:Water-Electrolyte Imbalance / Q000209:etiology*