title: Growth deficit in term small-for-gestational fetuses with normal umbilical artery Doppler is associated with adverse outcome.
abstract: OBJECTIVE
  The association between the growth deficit and the occurrence of adverse outcome was analyzed in a cohort of small-for-gestational age fetuses delivered at term.
  
  
  METHODS
  A cohort of consecutive singleton fetuses suspected of being SGA during the late third trimester and delivered beyond 37 weeks was selected. Growth deficit area was calculated as that between the individual 10(th) centile curve of the customized optimal fetal weight and the individual fetal growth curve.
  
  
  RESULTS
  A total of 55 women were included. Of these, 16 had 28 adverse events: eight cases of umbilical artery pH<7.15, 9 cases of caesarean section for fetal distress and 11 cases of admission to neonatal intensive care unit. Whereas the mean area of growth deficit was 8.8 kg x week units (SD 7.6) for cases with normal outcomes, it was 13.9 (SD 8.04) for cases with adverse outcomes (P=0.03). A growth area deficit >10 units, predicted the occurrence of adverse outcome with a sensitivity and specificity of 62% and 68%, respectively.
  
  
  CONCLUSIONS
  In term growth restricted fetuses the degree of growth deficit from the optimal customized growth may be used to identify a subgroup of fetuses at high-risk for adverse outcomes.
authors.affiliation: Department of Obstetrics, Hospital Clinic, Barcelona, Spain.
authors.forename: Miriam
authors.initials: M
authors.lastname: Illa
authors.forename: José L
authors.initials: JL
authors.lastname: Coloma
authors.forename: Elisenda
authors.initials: E
authors.lastname: Eixarch
authors.forename: Eva
authors.initials: E
authors.lastname: Meler
authors.forename: Ainara
authors.initials: A
authors.lastname: Iraola
authors.forename: Jason
authors.initials: J
authors.lastname: Gardosi
authors.forename: Eduard
authors.initials: E
authors.lastname: Gratacós
authors.forename: Francesc
authors.initials: F
authors.lastname: Figueras
mesh_terms: D015331:Cohort Studies; D005260:Female; D005317:Fetal Growth Retardation; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D018566:Pregnancy, High-Risk; D012680:Sensitivity and Specificity; D047929:Term Birth; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging*