Inhibitors and antagonists of bacterial quorum sensing.
Bacteria can regulate community-wide behaviors including biofilm formation, virulence, conjugation, sporulation, and swarming motility through a process called quorum sensing. Inhibitors and antagonists of bacterial quorum sensing are important research tools and potential therapeutic agents. In this review, we have summarized recent developments in this area.
Ni
Nanting
N
Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302-4098, USA.
Li
Minyong
M
Wang
Junfeng
J
Wang
Binghe
B
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000201:enzymology; D000071677:Histidine Kinase; D009842:Oligopeptides / Q000737:chemistry* / Q000494:pharmacology; D047428:Protein Kinase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D011494:Protein Kinases / Q000187:drug effects; D053038:Quorum Sensing / Q000187:drug effects* / Q000502:physiology; D015398:Signal Transduction; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D009842:Oligopeptides; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases; D000071677:Histidine Kinase