title: Aryl-aryl crosss-couplings that avoid the preparation of haloaromatics.
abstract: Advances in the development of cross-coupling protocols that avoid haloaromatics are reviewed. Most of the reports that are discussed appeared in the literature within the past 2 years and describe either alternatives to halogenated electrophiles or halogen-free preparations of the organometallic partners. However, while this review is not limited to cross-couplings that are entirely free of haloaromatics, coverage of the topic is largely restricted to reactions affording new aryl-aryl, aryl-heteroaryl and heteroaryl-heteroaryl carbon-carbon bonds during the cross-coupling event.
authors.affiliation: Michigan State University, Department of Chemistry, 540 Chemistry, East Lansing, MI 48824, USA.
authors.forename: A Monica
authors.initials: AM
authors.lastname: Norberg
authors.forename: Luis
authors.initials: L
authors.lastname: Sanchez
authors.forename: Robert E
authors.initials: RE
authors.lastname: Maleczka
mesh_terms: D002384:Catalysis; D002626:Chemistry, Pharmaceutical; D055808:Drug Discovery; D006219:Halogens / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*
chemical_list: D006219:Halogens; D004364:Pharmaceutical Preparations