Brain protection by erythropoietin: a manifold task.
Many hematopoietic growth factors are produced locally in the brain. Among these, erythropoietin (Epo), has a dominant role for neuroprotection, neurogenesis, and acting as a neurotrophic factor in the central nervous system. These functions make erythropoietin a good candidate for treating diseases associated with neuronal cell death.
Rabie
Tamer
T
Institute of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany.
Marti
Hugo H
HH
D000818:Animals; D001921:Brain / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D004921:Erythropoietin / Q000096:biosynthesis / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy; D009424:Nervous System Physiological Phenomena; D017467:Receptors, Erythropoietin / Q000096:biosynthesis; D011994:Recombinant Proteins; D015398:Signal Transduction / Q000502:physiology
D017467:Receptors, Erythropoietin; D011994:Recombinant Proteins; D004921:Erythropoietin