A convenient iodination method for alcohols using cesium iodide/methanesulfonic acid and its comparison using cesium iodide/p-toluenesulfonic acid or cesium iodide/aluminium chloride.
In situ generation of hydrogen iodide from cesium iodide/methanesulfonic acid was found to be an attractive reagent combination for the conversion of alkyl, allyl, and benzyl alcohols to their corresponding iodides under mild conditions. The method is compared with that using cesium iodide/p-toluenesulfonic acid or cesium iodide/aluminium chloride.
Khan
Khalid Mohammed
KM
HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan. hassaan2@super.net.pk
Zia-Ullah
Perveen
Shahnaz
S
Hayat
Safdar
S
Ali
Muhammad
M
Voelter
Wolfgang
W
D000438:Alcohols / Q000737:chemistry*; D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000737:chemistry*; D001557:Benzenesulfonates / Q000737:chemistry*; D002586:Cesium / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D007454:Iodides / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*
D000438:Alcohols; D017607:Aluminum Compounds; D001557:Benzenesulfonates; D002712:Chlorides; D007454:Iodides; D002586:Cesium; D000077410:Aluminum Chloride; D007455:Iodine; C029501:4-toluenesulfonic acid; C040050:cesium iodide