title: Pseudouridines in rRNA helix 69 play a role in loop stacking interactions.
abstract: The (1)H NMR spectra of RNAs representing E. coli 23S rRNA helix 69 with [1,3-(15)N]pseudouridine modification at specific sites reveal unique roles for pseudouridine in stabilizing base-stacking interactions in the hairpin loop region.
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Desaulniers
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Chang
authors.forename: Raviprasad
authors.initials: R
authors.lastname: Aduri
authors.forename: Sanjaya C
authors.initials: SC
authors.lastname: Abeysirigunawardena
authors.forename: John
authors.initials: J
authors.lastname: SantaLucia
authors.forename: Christine S
authors.initials: CS
authors.lastname: Chow
mesh_terms: D020029:Base Pairing; D001483:Base Sequence; D055029:Inverted Repeat Sequences / Q000235:genetics; D009690:Nucleic Acid Conformation; D011522:Protons; D011560:Pseudouridine / Q000737:chemistry* / Q000235:genetics; D012338:RNA, Ribosomal, 23S / Q000737:chemistry* / Q000235:genetics
chemical_list: D011522:Protons; D012338:RNA, Ribosomal, 23S; D011560:Pseudouridine