Neural correlates of hemianopic completion across the vertical meridian.
Hemianopic completion refers to the perceptual completion of figures located across the vertical meridian in the context of hemianopia, such that one half of the figure falls within the blind hemifield. It can occur whether the figure is itself complete (veridical completion) or incomplete (paracompletion). Psychophysical evidence suggests that this phenomenon may be a constructive one, and may share features with completion phenomena in normal vision. The neural structures mediating hemianopic completion are unknown. Here we studied the neural activity evoked by hemianopic completion using event-related fMRI in an individual (POV) with a large right visual field homonymous hemianopic scotoma due to left occipital damage. Either a large achromatic circular contour straddling the vertical meridian or a semicircular contour within the left hemifield just crossing the vertical meridian was presented to POV on each trial. POV indicated by button press whether he perceived a semicircular contour, a patchy circular contour or a complete circular contour. On trials where he reported perceiving a complete circular contour despite being presented with a semicircular contour (paracompletion), activity was increased in a region of ipsilateral extrastriate cortex (contralateral to the lesion, ipsilateral to the illusory edge of the circle). These results are discussed in the context of illusory contour completion in healthy subjects and more generally in the recovery of function after brain damage.
Weil
R S
RS
Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, UK. r.weil@fil.ion.ucl.ac.uk
Plant
G T
GT
James-Galton
M
M
Rees
G
G
D000368:Aged; D003627:Data Interpretation, Statistical; D005403:Fixation, Ocular; D007839:Functional Laterality; D006423:Hemianopsia / Q000523:psychology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000150:complications / Q000601:surgery; D009778:Occipital Lobe / Q000502:physiology; D010466:Perceptual Closure / Q000502:physiology*; D010775:Photic Stimulation; D012607:Scotoma / Q000523:psychology; D015173:Supratentorial Neoplasms / Q000150:complications / Q000601:surgery; D014793:Visual Cortex / Q000502:physiology; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*