title: [Fruit of the emergence of an enterovirus: acute haemorrhagic conjunctivitis].
abstract: First seen in Ghana and Indonesia in the early 70's, acute haemorrhagic conjunctivitis or "Apollo 11" disease is an eye infection caused by Enterovirus type 70 (EV70). The disease appeared to be a highly contagious conjunctivitis which spread rapidly all over the world. EV70 has been considered as an emerging virus and was classified as a new Enterovirus. No human or animal virus genetically similar to EV70 was known before the sudden outcome of the disease in Ghana, West Africa. EV70 appeared as a pretty demonstrative example of virus emergence and virus spreading. Studies of virus genetic mutations emphasized the variations of RNA virus within a short time period. The current review presents the EV70 infection and the genetic profile of the virus from its emergence to nowadays.
authors.affiliation: Laboratoire de virologie/UPRES EA 3610, Faculté de médecine, Université de Lille 2, CHRU de Lille.
authors.forename: F
authors.initials: F
authors.lastname: Sane
authors.forename: P
authors.initials: P
authors.lastname: Sauter
authors.forename: S
authors.initials: S
authors.lastname: Fronval
authors.forename: A
authors.initials: A
authors.lastname: Goffard
authors.forename: A
authors.initials: A
authors.lastname: Dewilde
authors.forename: D
authors.initials: D
authors.lastname: Hober
mesh_terms: D000349:Africa / Q000453:epidemiology; D001208:Asia / Q000453:epidemiology; D003232:Conjunctivitis, Acute Hemorrhagic / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology; D003937:Diagnosis, Differential; D030016:Enterovirus D, Human / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology; D004769:Enterovirus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology; D005060:Europe / Q000453:epidemiology; D005814:Genes, Viral / Q000235:genetics; D014644:Genetic Variation; D006801:Humans; D009154:Mutation; D020133:Reverse Transcriptase Polymerase Chain Reaction