title: Zinc-mediated allylation and alkylation of aminals in the presence of TMSCl and diisopropylamine.
abstract: An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, alpha-bromoacetate, and alpha-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.
authors.affiliation: Division of Chemistry, Graduate School of Science and Engineering, Yamagata University, 4-3-16 Jonan, Yonezawa, 992-8510, Japan. hatano@yz.yamagata-u.ac.jp
authors.forename: Bunpei
authors.initials: B
authors.lastname: Hatano
authors.forename: Keita
authors.initials: K
authors.lastname: Nagahashi
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Kijima