Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagents.
Phenyl- and ethyl-magnesium bromides undergo regioselective asymmetric allylic substitution with high enantioselectivity under the catalysis of chiral amidophosphane-copper(I) complexes.
Selim
Khalid B
KB
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto, 606-8501, Japan.
Yamada
Ken-ichi
K
Tomioka
Kiyoshi
K
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007202:Indicators and Reagents; D017616:Magnesium Compounds / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry; D013237:Stereoisomerism
D007202:Indicators and Reagents; D017616:Magnesium Compounds; D009942:Organometallic Compounds; D003300:Copper