title: Developmental systems biology flourishing on new technologies.
abstract: Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational and modeling approaches have opened new frontiers for both systems biologists and developmental biologists to reexamine the old developmental biology questions, such as pattern formation, and to tackle new problems, such as stem cell reprogramming. As showcased in the International Developmental Systems Biology Symposium organized by Chinese Academy of Sciences, developmental systems biology is flourishing in many perspectives, from the evolution of developmental systems, to the underlying genetic and molecular pathways and networks, to the genomic, epigenomic and noncoding levels, to the computational analysis and modeling. We believe that the field will continue to reap rewards into the future with these new approaches.
authors.affiliation: Chinese Academy of Sciences Key Laboratory of Molecular Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. jdhan@genetics.ac.cn
authors.forename: Jing-Dong J
authors.initials: JD
authors.lastname: Han
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Huiling
authors.initials: H
authors.lastname: Xue
authors.forename: Kai
authors.initials: K
authors.lastname: Xia
authors.forename: Hong
authors.initials: H
authors.lastname: Yu
authors.forename: Shanshan
authors.initials: S
authors.lastname: Zhu
authors.forename: Zhang
authors.initials: Z
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
authors.forename: Chunyu
authors.initials: C
authors.lastname: Jin
authors.forename: Bo
authors.initials: B
authors.lastname: Xian
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Hou
authors.forename: Yixing
authors.initials: Y
authors.lastname: Han
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Niu
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Alcon
mesh_terms: D000818:Animals; D019295:Computational Biology; D015509:Developmental Biology / Q000379:methods*; D044127:Epigenesis, Genetic; D019143:Evolution, Molecular; D023281:Genomics; D006801:Humans; D022661:RNA, Untranslated / Q000235:genetics / Q000378:metabolism; D049490:Systems Biology / Q000379:methods*
chemical_list: D022661:RNA, Untranslated