title: Chemical characterization and biological activity of essential oils from Daucus carota L. subsp. carota growing wild on the Mediterranean coast and on the Atlantic coast.
abstract: The essential oils and supercritical CO(2) extracts of wild Daucus carota L. subsp. carota growing spontaneously in Sardinia and in Portugal were investigated. The main components in the Sardinian essential oil of flowering and mature umbels with seeds are beta-bisabolene (17.6-51.0%) and 11-alpha-(H)-himachal-4-en-1-beta-ol (9.0-21.6%); instead, the oils from Portuguese samples are predominantly composed of geranyl acetate (5.2-65.0%) and alpha-pinene (3.5-37.9%). Supercritical extracts contain lower amounts of monoterpenes and higher amounts of sesquiterpene hydrocarbons. Antifungal activities of the Sardinian oils were the highest, particularly for dermatophytes and Cryptococcus neoformans, with MIC values of 0.16-0.64 microL mL(-1).
authors.affiliation: Dipartimento di Scienze Botaniche and Co.S.Me.Se, Università degli Studi di Cagliari, Viale Sant'Ignazio, I-09123 Cagliari, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Maxia
authors.forename: Bruno
authors.initials: B
authors.lastname: Marongiu
authors.forename: Alessandra
authors.initials: A
authors.lastname: Piras
authors.forename: Silvia
authors.initials: S
authors.lastname: Porcedda
authors.forename: Enrica
authors.initials: E
authors.lastname: Tuveri
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Gonçalves
authors.forename: Carlos
authors.initials: C
authors.lastname: Cavaleiro
authors.forename: Ligia
authors.initials: L
authors.lastname: Salgueiro
mesh_terms: D000085:Acetates / Q000494:pharmacology; D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents / Q000494:pharmacology*; D000081008:Bicyclic Monoterpenes; D018552:Daucus carota / Q000737:chemistry*; D035264:Flowers; D005658:Fungi / Q000187:drug effects*; D007558:Italy; D008826:Microbial Sensitivity Tests; D000081222:Monocyclic Sesquiterpenes; D039821:Monoterpenes / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011174:Portugal; D012639:Seeds; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology; D013729:Terpenes / Q000494:pharmacology*
chemical_list: C539599:11-alpha-(H)-himachal-4-en-1-beta-ol; D000085:Acetates; D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents; D000081008:Bicyclic Monoterpenes; D000081222:Monocyclic Sesquiterpenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; D013729:Terpenes; C432872:geranyl acetate; C005451:alpha-pinene; C531191:beta-bisabolene