Limb defects in a fetus with homozygous alpha-thalassemia.
A fetus with homozygous alpha-thalassemia (alpha-thal) who displayed limb reduction defects is described. These kinds of congenital anomalies should be surveyed by sonography in at-risk pregnancies and included in genetic counseling prior to in utero fetal therapy.
Li
Jian
J
Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, China.
Li
Dongzhi
D
D000328:Adult; D005260:Female; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D017880:Limb Deformities, Congenital / Q000000981:diagnostic imaging* / Q000235:genetics; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D017085:alpha-Thalassemia / Q000000981:diagnostic imaging* / Q000235:genetics