title: Silent aortic dissection presenting as transient locked-in syndrome.
abstract: Acute aortic dissection is a medical emergency. Without prompt recognition and treatment, the mortality rate is high. An atypical presentation makes timely diagnosis difficult, especially if the patient is experiencing no characteristic pain. Many patients with aortic dissection are reported to have presented with various neurologic manifestations, but none with only a presentation of transient locked-in syndrome.Herein, we report a case of completely painless aortic dissection in a woman who presented with a transient episode of anarthria, quadriplegia, and preserved consciousness. On physical examination, she had a 40-point difference in blood pressure between her left and right arms, and a loud diastolic murmur. The diagnosis of acute aortic dissection was reached via a combination of radiography, computed tomography, echocardiography, and a high index of clinical suspicion. The patient underwent emergency surgery and ultimately experienced a successful outcome.To our knowledge, this is the 1st report of aortic dissection that presented solely as locked-in syndrome. We suggest that silent aortic dissection be added to the differential diagnosis for transient locked-in syndrome.
authors.affiliation: Internal Medicine Department, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA. NadourW@aol.com
authors.forename: Wadih
authors.initials: W
authors.lastname: Nadour
authors.forename: Brian
authors.initials: B
authors.lastname: Goldwasser
authors.forename: Robert W
authors.initials: RW
authors.lastname: Biederman
authors.forename: Kevin
authors.initials: K
authors.lastname: Taffe
mesh_terms: D000784:Aortic Dissection / Q000175:diagnosis* / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis* / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000601:surgery; D003937:Diagnosis, Differential; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D008875:Middle Aged; D011782:Quadriplegia / Q000209:etiology*; D014057:Tomography, X-Ray Computed