title: Molecular and Biological Characterization of Lettuce mosaic virus (LMV) Isolates Reveals a Distinct and Widespread Type of Resistance-Breaking Isolate: LMV-Most.
abstract: ABSTRACT Lettuce mosaic virus (LMV) causes an economically important seedborne and aphid-transmitted disease of lettuce and ornamental crops worldwide. The genetic diversity among 73 LMV isolates was examined based on a 216-nucleotide sequence at the variable region encoding the NIb-coat protein junction. Three clusters of LMV isolates were distinguished: LMV-Yar, LMV-Greek, and LMV-RoW. In the latter cluster, two subgroups of isolates, LMV-Common and LMV-Most, accounted for a large proportion of the LMV isolates analyzed. These two subgroups included the seedborne isolates, consistent with this property contributing a selective advantage and resulting in widespread distribution. In addition to being seedborne, LMV-Most isolates overcome the two resistance genes commonly used in lettuce, mo1(1) and mo1(2), and thus represent a potential threat to lettuce cultivation. The complete sequence of an LMV-Most isolate (LMV-AF199) was determined, allowing a better definition of the genetic relationships among LMV-Most, LMV-Common, and an additional isolate of the LMV-RoW cluster.
authors.forename: Renate
authors.initials: R
authors.lastname: Krause-Sakate
authors.forename: Olivier
authors.initials: O
authors.lastname: Le Gall
authors.forename: Hatem
authors.initials: H
authors.lastname: Fakhfakh
authors.forename: Martine
authors.initials: M
authors.lastname: Peypelut
authors.forename: Mohammed
authors.initials: M
authors.lastname: Marrakchi
authors.forename: Christina
authors.initials: C
authors.lastname: Varveri
authors.forename: Marcelo A
authors.initials: MA
authors.lastname: Pavan
authors.forename: Sylvie
authors.initials: S
authors.lastname: Souche
authors.forename: Hervé
authors.initials: H
authors.lastname: Lot
authors.forename: F Murilo
authors.initials: FM
authors.lastname: Zerbini
authors.forename: Thierry
authors.initials: T
authors.lastname: Candresse