title: Enhancement of entrapping ability of dendrimers by a cubic silsesquioxane core.
abstract: We report that a polyhedral oligomeric silsesquioxane (POSS) core can enhance the entrapping ability of dendrimers. Compared to the G2 PAMAM dendrimer, the G2 POSS-core dendrimer can entrap a larger amount of guest molecules without loss of affinity, and consequently, the water solubility of the entrapped guest molecules can be increased. In addition, we demonstrated that a fluorophore entrapped in the G2 POSS-core dendrimer was prevented from undergoing fluorescence photobleaching.
authors.affiliation: Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kenichi
authors.initials: K
authors.lastname: Inafuku
authors.forename: Kensuke
authors.initials: K
authors.lastname: Naka
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Chujo
mesh_terms: D050091:Dendrimers / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry; D012995:Solubility; D013050:Spectrometry, Fluorescence; D013696:Temperature; D014867:Water / Q000737:chemistry
chemical_list: D050091:Dendrimers; D017646:Organosilicon Compounds; D012235:Rhodamines; C521417:polyhedraloligosilsesquioxane; C026188:rhodamine 6G; D014867:Water