title: [Clinical related factors of portal vein tumor thrombosis in patients with hepatocellular carcinoma: a logistic regression analysis].
abstract: OBJECTIVE
  To investigate the related factors of portal vein tumor thrombosis (PVTT) in patients with HCC.
  
  
  METHODS
  A total number of 234 patients with hepatocellular carcinoma (HCC) were included in this retrospective study. Uni-variate and multi-variate logistic regression analysis were employed to analyze the association between PVTT and 18 routine clinical parameters.
  
  
  RESULTS
  Among the 234 patients with HCC, 15% of patients (35/235) had PVTT. Univariate logistic regression analysis revealed significant association of age (P = 0.016), gamma glutamyl transferase (GGT, P = 0.003), number of segmental invasion (P = 0.007), microvascular invasion (P < 0.01), segment location of S2 (P = 0.001), S3 (P = 0.000), S4 (P = 0.004) and S6 (P = 0.016). Multivariate analysis shows potential significant predictors of PVTT in HCC were age (RR: 0.373; 95% CI: 0.146-0.954; P = 0.040), the tumor location of S3 (RR: 4.625; 95% CI: 1.916-11. 165;P = 0.001), GGT (RR: 4.091; 95% CI: 1.448-11.553; P = 0.008) and microvascular invasion (RR: 20.912; 95% CI: 4.745-92.172; P < 0.01).
  
  
  CONCLUSIONS
  PVTT occurred more commonly in the younger (< 50 years old), and those with high level of GGT, segment location of S3 and microvascular invasion.
authors.affiliation: Department of Hepatobilliary Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
authors.forename: Wen-Ping
authors.initials: WP
authors.lastname: Lü
authors.forename: Jia-Hong
authors.initials: JH
authors.lastname: Dong
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Huang
authors.forename: Shuang
authors.initials: S
authors.lastname: Shi
authors.forename: De-Yu
authors.initials: DY
authors.lastname: Guo
authors.forename: You-Sheng
authors.initials: YS
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002648:Child; D004617:Embolism / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D012189:Retrospective Studies; D012307:Risk Factors