Proliferative lupus nephritis in a patient with systemic lupus erythematosus and longstanding secondary amyloid nephropathy.
Secondary amyloidosis is an unusual complication of systemic lupus erythematosus (SLE). We report the case of a 60-year-old woman with SLE and secondary amyloidosis who developed class III proliferative lupus nephritis 13 years after the onset of amyloid nephropathy. The patient was treated with mycophenolate mofetil (1.5 g/day) with a significant improvement in proteinuria.
Gómez-Puerta
Jose A
JA
Department of Rheumatology, Hospital Clínic, Barcelona, Spain. jagomez@clinic.ub.es
Cervera
Ricard
R
Moll
Concepción
C
Solé
Manel
M
Collado
Antonio
A
Sanmartí
Raimon
R
D000682:Amyloid / Q000378:metabolism; D000686:Amyloidosis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism / Q000473:pathology*; D007678:Kidney Glomerulus / Q000378:metabolism / Q000473:pathology; D008181:Lupus Nephritis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011507:Proteinuria / Q000188:drug therapy; D016896:Treatment Outcome
D000682:Amyloid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009173:Mycophenolic Acid