[Myopathy with rhabdomyolysis as an adverse effect of simultaneous treatment with cerivastatin and gemfibrozil].
Drug-induced myopathy and/or rhabdomyolysis have been reported with use of some statins and fibric acid derivatives. The risk of adverse effects is increased with their concomitant use. We report the case of myopathy with rhabdomyolysis during the concomitant use of cerivastatin and gemfibrozil.
Huić
Mirjana
M
Zavod za klinicku farmakologiju, Klinika za unutarnje bolesti Rebro, KBC Zagreb, Kispatićeva 12, 10000 Zagreb.
Anić
Branimir
B
Cikes
Nada
N
Bosnić
Dubravka
D
Sentić
Mirna
M
Markeljević
Jasenka
J
Mayer
Miroslav
M
Pazanin
Leo
L
D000368:Aged; D004347:Drug Interactions; D005260:Female; D015248:Gemfibrozil / Q000009:adverse effects*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D000960:Hypolipidemic Agents / Q000009:adverse effects*; D009135:Muscular Diseases / Q000139:chemically induced*; D011725:Pyridines / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D011725:Pyridines; C086276:cerivastatin; D015248:Gemfibrozil