title: Uni-centric localization of Castleman's disease treated with laparoscopic and traditional approach. Report of two cases.
abstract: Castleman's disease (CD) is a rare lymphoproliferative disorder. Clinically CD has been subdivided in two forms: uni-centric and multicentric. The uni-centric type is limited to a single anatomic lymph-node-bearing region. The present report describes two cases of uni-centric CD: the first was an abdominal localization treated with a laparoscopic approach; the second was a submaxillary localization treated with a classical approach. In case 1 the laparoscopic approach permitted to reach diagnosis, not clear after diagnostic imaging procedures, and enabled a total and excellent resolution of the pathology because our patient, after eight months of follow up, has had no evidence of recurrence of the disease. In case 2 we want to highlight that CD should be considered in the differential diagnosis of a solitary neck mass and that the surgical treatment is diagnostic and curative at the same time.
authors.affiliation: University of Rome La Sapienza, Department of Surgical Sciences, Rome.
authors.forename: F
authors.initials: F
authors.lastname: Tartaglia
authors.forename: S
authors.initials: S
authors.lastname: Blasi
authors.forename: A
authors.initials: A
authors.lastname: Berni
authors.forename: M
authors.initials: M
authors.lastname: Sgueglia
authors.forename: P
authors.initials: P
authors.lastname: Polichetti
authors.forename: A
authors.initials: A
authors.lastname: Maturo
authors.forename: G
authors.initials: G
authors.lastname: Palazzini
authors.forename: L
authors.initials: L
authors.lastname: Tromba
authors.forename: F P
authors.initials: FP
authors.lastname: Campana
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000328:Adult; D005871:Castleman Disease / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000601:surgery; D013363:Submandibular Gland / Q000601:surgery*; D016896:Treatment Outcome