title: Eosinophilic granuloma presenting with local osteolysis in an adult lumbar spine.
abstract: We report an adult patient with eosinophilic granuloma presenting as a local lytic lesion of a vertebral body in the lumbar spine. The patient was a 48-year-old man with a 2-month history of low back pain and numbness in both legs. On plain X-ray, a lytic lesion of the L2 vertebral body was noted. On MRI, the lesion exhibited low-intensity change on T(1)-weighted images, high-intensity change on T(2)-weighted images, and was homogeneously enhanced by gadolinium. The lesion was surgically treated by curettage and iliac bone grafting using a retroperitoneal approach. Histologically, a specimen obtained at the time of surgery was found to be eosinophilic granuloma. We present details of this extremely rare case and review the literature.
authors.affiliation: Department of Orthopaedic Surgery, Osaka City General Hospital, Miyakojima-ku, Osaka 534-0021, Japan. hnakamura@med.osaka-cu.ac.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nakamura
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Nagayama
mesh_terms: D004803:Eosinophilic Granuloma / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000150:complications* / Q000473:pathology*; D013131:Spine / Q000473:pathology