Cell surface enzyme attachment is mediated by family 37 carbohydrate-binding modules, unique to Ruminococcus albus.
The rumen bacterium Ruminococcus albus binds to and degrades crystalline cellulosic substrates via a unique cellulose degradation system. A unique family of carbohydrate-binding modules (CBM37), located at the C terminus of different glycoside hydrolases, appears to be responsible both for anchoring these enzymes to the bacterial cell surface and for substrate binding.
Ezer
Anat
A
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel.
Matalon
Erez
E
Jindou
Sadanari
S
Borovok
Ilya
I
Atamna
Nof
N
Yu
Zhongtang
Z
Morrison
Mark
M
Bayer
Edward A
EA
Lamed
Raphael
R
D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism*; D001665:Binding Sites; D002482:Cellulose / Q000378:metabolism*; D003001:Cloning, Molecular; D006026:Glycoside Hydrolases / Q000378:metabolism*; D009154:Mutation; D011485:Protein Binding; D045857:Ruminococcus / Q000201:enzymology*; D013379:Substrate Specificity
D001426:Bacterial Proteins; D002482:Cellulose; D006026:Glycoside Hydrolases