title: Quick two-dimensional differential in gel electrophoresis-based method to determine length and secondary structures of telomeric DNA.
abstract: A novel differential in gel electrophoresis (DIGE)-based method has been developed and applied to measure telomere length and appearance of two-dimensional structural DNA changes. It can be applied to any area requiring quick and evident measurement of structural DNA changes.
authors.affiliation: Department of Genetics and Microbiology, Universitad Autonoma de Barcelona, Edifici C UAB Campus, Bellaterra 08193, Spain. alex.lyakhovich@uab.es
authors.forename: Alex
authors.initials: A
authors.lastname: Lyakhovich
authors.forename: Joan J
authors.initials: JJ
authors.lastname: Bech-Serra
authors.forename: Francesc
authors.initials: F
authors.lastname: Canals
authors.forename: Jordi
authors.initials: J
authors.lastname: Surralles
mesh_terms: D004247:DNA / Q000737:chemistry*; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D009690:Nucleic Acid Conformation; D013329:Structure-Activity Relationship; D016615:Telomere / Q000737:chemistry*
chemical_list: D004247:DNA