title: A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats.
abstract: In adult albino (SD) and pigmented (PVG) rats the entire population of retinal ganglion cells (RGCs) was quantified and their spatial distribution analyzed using a computerized technique. RGCs were back-labelled from the optic nerves (ON) or the superior colliculi (SCi) with Fluorogold (FG). Numbers of RGCs labelled from the ON [SD: 82,818+/-3,949, n=27; PVG: 89,241+/-3,576, n=6) were comparable to those labelled from the SCi [SD: 81,486+/-4,340, n=37; PVG: 87,229+/-3,199; n=59]. Detailed methodology to provide cell density information at small scales demonstrated the presence of a horizontal region in the dorsal retina with highest densities, resembling a visual streak.
authors.affiliation: Laboratorio de Oftalmología Experimental, Facultad de Medicina, Universidad de Murcia, E-30100 Murcia, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Salinas-Navarro
authors.forename: S
authors.initials: S
authors.lastname: Mayor-Torroglosa
authors.forename: M
authors.initials: M
authors.lastname: Jiménez-López
authors.forename: M
authors.initials: M
authors.lastname: Avilés-Trigueros
authors.forename: T M
authors.initials: TM
authors.lastname: Holmes
authors.forename: R D
authors.initials: RD
authors.lastname: Lund
authors.forename: M P
authors.initials: MP
authors.lastname: Villegas-Pérez
authors.forename: M
authors.initials: M
authors.lastname: Vidal-Sanz
mesh_terms: D000818:Animals; D002452:Cell Count; D001330:Electronic Data Processing; D005260:Female; D005456:Fluorescent Dyes; D008297:Male; D008856:Microscopy, Fluorescence; D009900:Optic Nerve; D051381:Rats; D011914:Rats, Inbred BN; D017207:Rats, Sprague-Dawley; D015203:Reproducibility of Results; D012165:Retinal Ganglion Cells / Q000166:cytology*; D013045:Species Specificity; D013477:Superior Colliculi
chemical_list: D005456:Fluorescent Dyes