Better smelling through genetics: mammalian odor perception.
The increasing availability of genomic and genetic tools to study olfaction-the sense of smell-has brought important new insights into how this chemosensory modality functions in different species. Newly sequenced mammalian genomes-from platypus to dog-have made it possible to infer how smell has evolved to suit the needs of a given species and how variation within a species may affect individual olfactory perception. This review will focus on recent advances in the genetics and genomics of mammalian smell, with a primary focus on rodents and humans.
Keller
Andreas
A
Laboratory of Neurogenetics and Behavior, The Rockefeller University, 1230 York Avenue, Box 63, New York, NY 10065, USA.
Vosshall
Leslie B
LB
D000818:Animals; D014644:Genetic Variation; D023281:Genomics / Q000379:methods; D006801:Humans; D008954:Models, Biological; D009812:Odorants; D055696:Olfactory Perception / Q000235:genetics* / Q000502:physiology; D018035:Receptors, Odorant / Q000235:genetics* / Q000502:physiology; D012903:Smell / Q000235:genetics* / Q000502:physiology; D013045:Species Specificity
D018035:Receptors, Odorant