title: Rapid enantiomeric excess and concentration determination using simple racemic metal complexes.
abstract: Racemic-metal complexes were used to determine identity, enantiomeric excess, and concentration of chiral diamines using metal-to-ligand charge transfer bands in circular dichroism spectroscopy. It takes under just 2 min per sample to determine [G]t and %R with tolerable errors (19% and 4%, respectively). The simplicity of the achiral receptors employed confers to this technique great potential for high-throughput screening.
authors.affiliation: Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
authors.forename: Sonia
authors.initials: S
authors.lastname: Nieto
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Lynch
authors.forename: Eric V
authors.initials: EV
authors.lastname: Anslyn
authors.forename: Hyunwoo
authors.initials: H
authors.lastname: Kim
authors.forename: Jik
authors.initials: J
authors.lastname: Chin
mesh_terms: D002942:Circular Dichroism; D003959:Diamines / Q000032:analysis; D016014:Linear Models; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013997:Time Factors
chemical_list: D003959:Diamines; D009942:Organometallic Compounds