title: Validation of QwikStar Catheter for left ventricular electromechanical mapping with NOGA XP system.
abstract: Left ventricular electromechanical mapping (LVEM) is a method for mapping the left ventricular cavity in 3 dimensions by use of a catheter that samples points on the endocardial surface. These points provide data on unipolar voltage and linear local shortening, which can then be used to evaluate myocardial ischemia and viability. The new QwikStar multi-electrode catheter, which acquires data from multiple points simultaneously, potentially improves map quality and decreases mapping time in comparison with the single-point NogaStar catheter. Our study sought to validate the QwikStar catheter's LVEM capabilities in a porcine model of chronic ischemia.Eight pigs underwent ameroid placement over the proximal left circumflex artery, to induce chronic ischemia. In 60 days, LVEM was performed on each animal with the NogaStar and QwikStar catheters. Unipolar voltage and linear local shortening results were displayed in 9-segment polar maps. The unipolar voltage data from both maps were then correlated by means of linear regression.There were no adverse events during LVEM. Mapping time was similar for both groups (QwikStar, 44.6 +/- 25.62 min; NogaStar, 65.75 +/- 25.33 min; P = 0.13). Results of mean unipolar voltage maps acquired with the 2 catheters showed a moderate correlation (r =0.59, P <0.001). Selecting segments with more than 6 point samples increased the Pearson coefficient to 0.69 (P <0.001).Our findings show that the QwikStar catheter enables the reproducible performance of LVEM by sampling fewer points, which shortens procedure time, decreases manipulation of the left ventricular cavity, and might increase procedural safety.
authors.affiliation: Stem Cell Center, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA. Marlos.Fernandes@uth.tmc.edu
authors.forename: Marlos R
authors.initials: MR
authors.lastname: Fernandes
authors.forename: Guilherme V
authors.initials: GV
authors.lastname: Silva
authors.forename: Yi
authors.initials: Y
authors.lastname: Zheng
authors.forename: Edie M
authors.initials: EM
authors.lastname: Oliveira
authors.forename: Cristiano O
authors.initials: CO
authors.lastname: Cardoso
authors.forename: John
authors.initials: J
authors.lastname: Canales
authors.forename: Ricardo
authors.initials: R
authors.lastname: Sanz-Ruiz
authors.forename: Pilar
authors.initials: P
authors.lastname: Jimenez-Quevedo
authors.forename: Fred
authors.initials: F
authors.lastname: Baimbridge
authors.forename: Emerson C
authors.initials: EC
authors.lastname: Perin
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization; D004562:Electrocardiography / Q000295:instrumentation*; D004566:Electrodes; D022062:Electrophysiologic Techniques, Cardiac / Q000295:instrumentation*; D004699:Endocardium / Q000503:physiopathology; D004867:Equipment Design; D009200:Myocardial Contraction / Q000502:physiology; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000503:physiopathology; D013552:Swine; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000503:physiopathology