Enantiomerically pure bicyclo[3.3.1]nona-2,6-diene as the sole source of enantioselectivity in BIPHEP-Rh asymmetric hydrogenation.
In situ resolution of the rapidly racemising diphosphine BIPHEP and its relatives with the cationic Rh complex of (S,S)-bicyclonona-2,6-diene permits the asymmetric hydrogenation of dehydroamino esters.
Punniyamurthy
Tharmalingam
T
Chemical Research Laboratory, 12 Mansfield Rd, Oxford, UKOX1 3TA. tpunni@iitg.ernet.in
Mayr
Monika
M
Dorofeev
Alexander S
AS
Bataille
Carole J R
CJ
Gosiewska
Silvia
S
Nguyen
Bao
B
Cowley
Andrew R
AR
Brown
John M
JM