title: A novel form of aberrant innervation in congenital cranial dysinnervation disorder.
abstract: Certain forms of congenital incomitant strabismus are associated with abnormal cranial nerve development and resultant abnormal orbital innervation (eg, Duane retraction syndrome, congenital fibrosis of the extraocular muscles [CFEOM]); such conditions can be considered congenital cranial dysinnervation disorders (CCDDs). In addition to duction limitation and/or ptosis, orbital CCDD phenotypes include inappropriate extraocular muscle and/or levator innervation by nerves intended for innervation of other structures (eg, some of the innervation intended for the medial rectus muscle inappropriately innervating the ipsilateral lateral rectus muscle in Duane retraction syndrome). This report documents a unique orbital dysinnervational pattern-supraduction during attempted adduction and infraduction during attempted abduction in the left affected eye of a girl with exotropia and enophthalmos.
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Arif O
authors.initials: AO
authors.lastname: Khan
mesh_terms: D002675:Child, Preschool; D003391:Cranial Nerves / Q000002:abnormalities*; D015841:Enophthalmos / Q000151:congenital / Q000473:pathology*; D005099:Exotropia / Q000151:congenital / Q000473:pathology*; D005260:Female; D006801:Humans; D008850:Microphthalmos / Q000473:pathology*; D009801:Oculomotor Muscles / Q000294:innervation*