title: Identification of an F-box protein that negatively regulates P(i) starvation responses.
abstract: The Arabidopsis gene At5g21040 encodes a protein containing both WD40 and F-box motifs, termed FBX2. A T-DNA insertional mutant in this gene was obtained. Analysis of this mutant line showed that FBX2 is a negative regulator of several P(i) starvation responses. FBX2 interacts with BHLH32, another negative regulator of P(i) starvation responses. We suggest that FBX2 may be part of an SCF-like complex that recruits BHLH32 and its partners, potentially targeting the latter for proteolysis.
authors.affiliation: Plant Science Group, Division of Biochemistry & Molecular Biology, Faculty of Biomedical & Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Chen
authors.forename: Gareth I
authors.initials: GI
authors.lastname: Jenkins
authors.forename: Hugh G
authors.initials: HG
authors.lastname: Nimmo
mesh_terms: D000872:Anthocyanins / Q000378:metabolism; D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics / Q000378:metabolism; D004269:DNA, Bacterial / Q000235:genetics; D044783:F-Box Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D016254:Mutagenesis, Insertional; D009154:Mutation; D010710:Phosphates / Q000378:metabolism*; D018749:RNA, Plant / Q000235:genetics
chemical_list: D000872:Anthocyanins; D029681:Arabidopsis Proteins; D051792:Basic Helix-Loop-Helix Proteins; D004269:DNA, Bacterial; D044783:F-Box Proteins; D010710:Phosphates; D018749:RNA, Plant; C036483:T-DNA