title: Decreased oxidative stress index of urine in patients with urinary tract infection.
abstract: OBJECTIVE
  To investigate the oxidative and antioxidative status of urine and serum of patients with urinary tract infection (UTI) and to compare them with those of controls.
  
  
  METHODS
  The antioxidative status of urine and serum were evaluated by measuring total antioxidant capacity (TAC) and plasma vitamin C concentration. The oxidative status of the samples was assessed by measuring the total peroxide and the oxidative stress index (OSI) levels. The means of the parameters were compared and the relationships among them were determined.
  
  
  RESULTS
  Total peroxide and OSI levels were found to be lower and TAC was found to be higher in the urine of patients with UTI. On the contrary, while the plasma vitamin C concentration and TAC of serum was lower, the total peroxide and OSI levels were higher in patients than controls. There was a negative correlation between serum TAC and urine TAC values. There was also a positive correlation between plasma vitamin C concentration and serum TAC levels.
  
  
  CONCLUSIONS
  The urine of the patients with UTI have higher TAC and lower total peroxide and OSI levels. However, lower TAC and plasma vitamin C concentration and higher total peroxide and OSI levels were observed in UTI. This condition may be a factor which facilitates the development of the infection or is secondary to UTI.
authors.affiliation: Department of Urology, Balikligol State Hospital , Sanliurfa, Turkey.
authors.forename: Halil
authors.initials: H
authors.lastname: Ciftci
authors.forename: Ayhan
authors.initials: A
authors.lastname: Verit
authors.forename: Ercan
authors.initials: E
authors.lastname: Yeni
authors.forename: Murat
authors.initials: M
authors.lastname: Savas
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000097:blood; D015415:Biomarkers / Q000097:blood / Q000652:urine; D016022:Case-Control Studies; D015536:Down-Regulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress; D010545:Peroxides / Q000097:blood / Q000652:urine; D014552:Urinary Tract Infections / Q000097:blood* / Q000652:urine*; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D010545:Peroxides; D001205:Ascorbic Acid