Measurement of elastic properties of prostate cancer cells using AFM.
This communication reports that three prostate cancer cells of differing metastatic potential were discriminated based on their Young's moduli (LNCaP - 287 +/- 52 N m(-2), PC-3 - 1401 +/- 162 N m(-2) and BPH - 2797 +/- 491 N m(-2)) which were determined using AFM and the Hertz model.
Faria
Elsa Correia
EC
School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, UK. elsa.faria@manchester.ac.uk
Ma
Nan
N
Gazi
Ehsan
E
Gardner
Peter
P
Brown
Mick
M
Clarke
Noel W
NW
Snook
Richard D
RD
D000230:Adenocarcinoma / Q000473:pathology*; D045744:Cell Line, Tumor; D004548:Elasticity; D006801:Humans; D008297:Male; D018625:Microscopy, Atomic Force; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000473:pathology*