Identifying biological markers of activity in human nociceptive pathways to facilitate analgesic drug development.
Chizh
Boris A
BA
GlaxoSmithKline, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2GG, UK Department of Neural and Pain Sciences, Dental School and Program in Neuroscience, University of Maryland, Baltimore, MD 21201, USA University of Michigan and VA Medical Center, Ann Arbor, MI 48109, USA Pain Research Center, Anesthesia Department, Stanford University, Stanford, CA 94305 and LASMED LLC, Mountain View, CA 94043, USA Department of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM), University of Heidelberg, D-68167 Mannheim, Germany.
Greenspan
Joel D
JD
Casey
Kenneth L
KL
Nemenov
Michael I
MI
Treede
Rolf-Detlef
RD
D000344:Afferent Pathways / Q000187:drug effects* / Q000378:metabolism*; D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D003198:Computer Simulation; D015195:Drug Design; D006801:Humans; D008954:Models, Biological; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism
D000700:Analgesics; D015415:Biomarkers