title: [A retrospective study of 129 cases with immediate breast reconstruction after skin-sparing mastectomy for breast cancer].
abstract: OBJECTIVE
  To evaluate the oncologic safety, indications and aesthetic results for skin-sparing mastectomy (SSM) and immediate breast reconstruction (IBR).
  
  
  METHODS
  One hundred and twenty-nine breast cancer patients treated by SSM + IBR from October 1999 to May 2007 were reviewed. Reconstructive techniques included latissimus dorsi flaps (38 patients), implants only (2 patients), latissimus dorsi flaps plus implants (61 patients), pedicled transverse rectus abdominis myocutaneous (TRAM) flaps (25 patients) and deep inferior epigastric artery perforator (DIEP) flaps (3 patients). Aesthetic results were judged by patients' self-evaluation.
  
  
  RESULTS
  Mean duration of hospitalization was 18.6 days. Time of first chemotherapy was 5.2 days after operation. Eleven patients (11/63, 17.5%) developed capsular contracture and 24 patients (24/99, 24.2%) developed seroma in the donor site. Nine patients (9/28, 32.1%) developed partial fat necrosis in TRAM and DIEP flaps. The satisfaction with the aesthetic results of the reconstructive breast was significantly lower in irradiated patients than non-irradiated ones. Median follow-up time was 11 months. Five patients developed local recurrence and 7 patients with metastasis.
  
  
  CONCLUSIONS
  SSM with IBR can be used for the 0 to II a stage breast cancer patients, with surgical oncologic and aesthetic satisfaction. Radiotherapy has an adverse effect on the reconstructive breast. Delayed or delayed-immediate reconstructions are recommended for patients indicated to postoperative radiotherapy.
authors.affiliation: Department of Breast Surgery, Cancer Hospital, Fudan University, Shanghai 200032, China. wujiong1122@vip.sina.com
authors.forename: Jiong
authors.initials: J
authors.lastname: Wu
authors.forename: Gen-Hong
authors.initials: GH
authors.lastname: Di
authors.forename: Tian-Wen
authors.initials: TW
authors.lastname: Chen
authors.forename: Fa-Zhi
authors.initials: FZ
authors.lastname: Qi
authors.forename: Kun-Wei
authors.initials: KW
authors.lastname: Shen
authors.forename: Qi-Xia
authors.initials: QX
authors.lastname: Han
authors.forename: Zhen-Zhou
authors.initials: ZZ
authors.lastname: Shen
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Shao
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D015414:Mastectomy, Subcutaneous; D008875:Middle Aged; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome