title: HGVbaseG2P: a central genetic association database.
abstract: The Human Genome Variation database of Genotype to Phenotype information (HGVbaseG2P) is a new central database for summary-level findings produced by human genetic association studies, both large and small. Such a database is needed so that researchers have an easy way to access all the available association study data relevant to their genes, genome regions or diseases of interest. Such a depository will allow true positive signals to be more readily distinguished from false positives (type I error) that fail to consistently replicate. In this paper we describe how HGVbaseG2P has been constructed, and how its data are gathered and organized. We present a range of user-friendly but powerful website tools for searching, browsing and visualizing G2P study findings. HGVbaseG2P is available at http://www.hgvbaseg2p.org.
authors.affiliation: Department of Genetics, University of Leicester, University Road, Leicester, LE1 7RH, UK.
authors.forename: Gudmundur A
authors.initials: GA
authors.lastname: Thorisson
authors.forename: Owen
authors.initials: O
authors.lastname: Lancaster
authors.forename: Robert C
authors.initials: RC
authors.lastname: Free
authors.forename: Robert K
authors.initials: RK
authors.lastname: Hastings
authors.forename: Pallavi
authors.initials: P
authors.lastname: Sarmah
authors.forename: Debasis
authors.initials: D
authors.lastname: Dash
authors.forename: Samir K
authors.initials: SK
authors.lastname: Brahmachari
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Brookes
mesh_terms: D003196:Computer Graphics; D030541:Databases, Genetic; D014644:Genetic Variation; D015894:Genome, Human; D055106:Genome-Wide Association Study; D005838:Genotype; D006801:Humans; D010641:Phenotype; D012984:Software