title: Matriderm versus Integra: a comparative experimental study.
abstract: OBJECTIVE
  To compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin or Matriderm.
  
  
  METHODS
  Matriderm and the dermal part of Integra were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take.
  
  
  RESULTS
  Efficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices.
  
  
  CONCLUSIONS
  This first comparison of Matriderm with Integra in a rat model revealed no major differences in engraftment rates or vascularisation.
authors.affiliation: Paediatric Burn Centre, Plastic and Reconstructive Surgery, Department of Surgery, University Children's Hospital, Steinwiesstrasse 75, Zürich, Switzerland.
authors.forename: Joerg
authors.initials: J
authors.lastname: Schneider
authors.forename: Thomas
authors.initials: T
authors.lastname: Biedermann
authors.forename: Daniel
authors.initials: D
authors.lastname: Widmer
authors.forename: Irene
authors.initials: I
authors.lastname: Montano
authors.forename: Martin
authors.initials: M
authors.lastname: Meuli
authors.forename: Ernst
authors.initials: E
authors.lastname: Reichmann
authors.forename: Clemens
authors.initials: C
authors.lastname: Schiestl
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002809:Chondroitin Sulfates / Q000502:physiology*; D003094:Collagen / Q000502:physiology*; D004549:Elastin / Q000502:physiology*; D006085:Graft Survival / Q000502:physiology; D051381:Rats; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D016038:Skin Transplantation / Q000379:methods
chemical_list: C114835:integra artificial skin; C532298:matriderm; D002809:Chondroitin Sulfates; D003094:Collagen; D004549:Elastin