Determination of trenbolone residual in bovine liver by liquid chromatography-mass spectrometry.
A sensitive method was developed and validated for the quantitation of trenbolone residues in bovine liver. Target analytes were extracted from liver homogenate using solid phase cartridges, separated on a Phenyl column and detected using an electrospray ionization mass spectrometer operating in positive ion mode. The mean recovery of the analytes was between 62% and 69%. The method provided detection capabilities of 1 microg/kg for trenbolone. The method is suitable for application in veterinary drug residue in surveillance programme.
Wang
Hai
H
State key laboratory of environmental aquatic chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Science, Shuangqing Street, Haidian District, Beijing 100085, China. cadc2008@126.com
Wang
Zijian
Z
Shao
Bing
B
Liu
Ziru
Z
Liu
SuYing
S
D045930:Anabolic Agents / Q000032:analysis*; D000818:Animals; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis*; D008099:Liver / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D015813:Substance Abuse Detection / Q000379:methods*; D014204:Trenbolone Acetate / Q000032:analysis*; D019155:Veterinary Drugs / Q000032:analysis
D045930:Anabolic Agents; D019155:Veterinary Drugs; D014204:Trenbolone Acetate