An efficient synthesis of bis(indolyl)methanes and evaluation of their antimicrobial activities.
A versatile and efficient method has been developed for the synthesis of bis(indolyl)methanes by using aluminium triflate (0.5 mol%) as a novel catalyst. Further, some of the synthesized compounds were evaluated for their efficacy as antibacterial and antifungal activities. Most of the compounds have shown moderate to good inhibitory activity.
Kamal
Ahmed
A
Division of Organic Chemistry, Biotransformation Laboratory, Indian Institute of Chemical Technology, Hyderabad, India. ahmedkamal@iict.res.in
Khan
M Naseer A
MN
Srinivasa Reddy
K
K
Srikanth
Y V V
YV
Kaleem Ahmed
S
S
Pranay Kumar
K
K
Murthy
U S N
US
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D007211:Indoles; D008697:Methane