title: An efficient synthesis of chiral phosphinyl oxide pyrrolidines and their application to asymmetric direct aldol reactions.
abstract: Chiral pyrrolidine-based phosphinyl oxides were synthesized and their performance as organocatalysts for asymmetric direct aldol reactions was evaluated. High enantioselectivities and diastereoselectivies were achieved for a range of cyclic ketones and aromatic aldehydes.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 637371, Singapore. xuewei@ntu.edu.sg
authors.forename: Xue-Wei
authors.initials: XW
authors.lastname: Liu
authors.forename: Thanh Nguyen
authors.initials: TN
authors.lastname: Le
authors.forename: Yunpeng
authors.initials: Y
authors.lastname: Lu
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Xiao
authors.forename: Jimei
authors.initials: J
authors.lastname: Ma
authors.forename: Xingwei
authors.initials: X
authors.lastname: Li