title: Central hypoventilation syndrome after Haemophilus influenzae type b meningitis and herpes infection.
abstract: A case of central hypoventilation syndrome was identified in a child with brainstem and cervical cord injury following Haemophilus influenzae type b meningitis and extensive herpes simplex infection. This process resulted in a spastic tetraplegia, and the child continues to require respiratory support. Possible mechanisms of causation are discussed including an evolving, progressive inflammatory or vasculitic process in the setting of transient immunosuppression.
authors.affiliation: Department of Neurosciences, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
authors.forename: Sandya
authors.initials: S
authors.lastname: Tirupathi
authors.forename: David W
authors.initials: DW
authors.lastname: Webb
authors.forename: Ethna
authors.initials: E
authors.lastname: Phelan
authors.forename: Karina
authors.initials: K
authors.lastname: Butler
authors.forename: Joseph B
authors.initials: JB
authors.lastname: McMenamin
mesh_terms: D002675:Child, Preschool; D019741:Haemophilus influenzae type b; D006561:Herpes Simplex / Q000150:complications*; D006801:Humans; D007040:Hypoventilation / Q000382:microbiology* / Q000473:pathology / Q000821:virology*; D007223:Infant; D007238:Infarction / Q000382:microbiology / Q000473:pathology / Q000821:virology; D008279:Magnetic Resonance Imaging; D008297:Male; D008583:Meningitis, Haemophilus / Q000150:complications*; D011149:Pons / Q000473:pathology; D011782:Quadriplegia / Q000382:microbiology / Q000473:pathology / Q000821:virology; D012131:Respiratory Insufficiency / Q000382:microbiology / Q000473:pathology / Q000821:virology; D013116:Spinal Cord / Q000473:pathology