Nuclear roadblocks for mRNA export.
The THO complex and Sub2 RNA helicase have been shown to function in both transcription and mRNA processing. Rougemaille et al. (2008) now uncover evidence that THO/Sub2 coordinates mRNA processing and nuclear export.
Rondon
Ana G
AG
Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Proudfoot
Nick J
NJ
D021581:Active Transport, Cell Nucleus; D022022:Nuclear Pore / Q000378:metabolism*; D034443:RNA Transport; D012331:RNA, Fungal / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
D012331:RNA, Fungal; D029701:Saccharomyces cerevisiae Proteins