title: The ultrasound brain helmet: feasibility study of multiple simultaneous 3D scans of cerebral vasculature.
abstract: We describe early stage experiments to test the feasibility of an ultrasound brain helmet to produce multiple simultaneous real-time three-dimensional (3D) scans of the cerebral vasculature from temporal and suboccipital acoustic windows of the skull. The transducer hardware and software of the Volumetrics Medical Imaging (Durham, NC, USA) real-time 3D scanner were modified to support dual 2.5 MHz matrix arrays of 256 transmit elements and 128 receive elements which produce two simultaneous 64 degrees pyramidal scans. The real-time display format consists of two coronal B-mode images merged into a 128 degrees sector, two simultaneous parasagittal images merged into a 128 degrees x 64 degrees C-mode plane and a simultaneous 64 degrees axial image. Real-time 3D color Doppler scans from a skull phantom with latex blood vessel were obtained after contrast agent injection as a proof of concept. The long-term goal is to produce real-time 3D ultrasound images of the cerebral vasculature from a portable unit capable of internet transmission thus enabling interactive 3D imaging, remote diagnosis and earlier therapeutic intervention. We are motivated by the urgency for rapid diagnosis of stroke due to the short time window of effective therapeutic intervention.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC 27705, USA. ssmith@duke.edu
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Smith
authors.forename: Nikolas M
authors.initials: NM
authors.lastname: Ivancevich
authors.forename: Brooks D
authors.initials: BD
authors.lastname: Lindsey
authors.forename: John
authors.initials: J
authors.lastname: Whitman
authors.forename: Edward
authors.initials: E
authors.lastname: Light
authors.forename: Matthew
authors.initials: M
authors.lastname: Fronheiser
authors.forename: Heather A
authors.initials: HA
authors.lastname: Nicoletto
authors.forename: Daniel T
authors.initials: DT
authors.lastname: Laskowitz
mesh_terms: D002560:Cerebrovascular Circulation; D004453:Echoencephalography / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D005240:Feasibility Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D014159:Transducers; D018615:Ultrasonography, Doppler, Color / Q000295:instrumentation* / Q000379:methods*