title: [Preoperative accelerated radiotherapy for breast cancer--is it a historical delusion or a legitimate method of treatment?].
abstract: An effective procedure for preoperative chemoradiotherapy is suggested to intensify treatment of patients with extensive, local and/or regional, metastases of breast cancer. It uses medication followed by accelerated radiotherapy which offers the combined advantages of "concentrated" and "conventional" irradiation. High local and systemic effect is produced right at the outset thus making use of high-cost "first-line" cytostatics unnecessary and avoiding delay of surgical intervention.
authors.forename: V M
authors.initials: VM
authors.lastname: Vinogradov
authors.forename: I E
authors.initials: IE
authors.lastname: Isaeva
authors.forename: T L
authors.initials: TL
authors.lastname: Pirtskhalava
authors.forename: K M
authors.initials: KM
authors.lastname: Pozharisskiĭ
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods*; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant / Q000379:methods; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome