Fluorescent probe: complexation of Fe3+ with the myo-inositol 1,2,3-trisphosphate motif.
Natural myo-inositol phosphate antioxidants containing the 1,2,3-trisphosphate motif bind Fe(3+) in the unstable penta-axial conformation.
Mansell
David
D
School of Pharmacy & Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, UK M13 9PT.
Rattray
Nicholas
N
Etchells
Laura L
LL
Schwalbe
Carl H
CH
Blake
Alexander J
AJ
Bichenkova
Elena V
EV
Bryce
Richard A
RA
Barker
Christopher J
CJ
Díaz
Alvaro
A
Kremer
Carlos
C
Freeman
Sally
S
D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D015544:Inositol 1,4,5-Trisphosphate / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D014131:Trace Elements / Q000737:chemistry*; D014961:X-Ray Diffraction
D005456:Fluorescent Dyes; D014131:Trace Elements; D015544:Inositol 1,4,5-Trisphosphate; D007501:Iron