title: A unique case of collagenous colitis presenting as protein-losing enteropathy successfully treated with prednisolone.
abstract: A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99mTc-human serum albumin scintigraphy. Collagenous colitis associated with protein-losing enteropathy (PLE) without small bowel disease was diagnosed. Prednisolone treatment ameliorated diarrhea and hypoproteinemia. Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia for appropriate management.
authors.affiliation: Department of Internal Medicine, Osaka City General Hospital, 2-13-22, Miyakojima-ku, Osaka 534-0021, Japan.
authors.forename: Soichi
authors.initials: S
authors.lastname: Sano
authors.forename: Keiko
authors.initials: K
authors.lastname: Yamagami
authors.forename: Ayako
authors.initials: A
authors.lastname: Tanaka
authors.forename: Minako
authors.initials: M
authors.lastname: Nishio
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Nakamura
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kubo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inoue
authors.forename: Wataru
authors.initials: W
authors.lastname: Ueda
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Okawa
authors.forename: Katsunobu
authors.initials: K
authors.lastname: Yoshioka
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D046729:Colitis, Collagenous / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use*; D011504:Protein-Losing Enteropathies / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone