title: [Comparative study on the efficacy of cefuroxime, amoxycillin/clavulanic acid and fosfomycin in prophylaxis of nosocomial infections in oncologic patients after surgical operations].
abstract: Rational antibiotic prophylaxis and antibacterial therapy of nosocomial infections is an actual problem in surgery. Improvement of antimicrobial chemotherapy and prophylaxis of nosocomial infections is of special importance in urgent cases in oncologic units. Data on the design of rational schemes for antibacterial prophylaxis of nosocomial infections developing during the postoperative period in patients with cancer of the urinary bladder as one of the unfavourable complications of the main disease treatment are presented. The use of fosfomycin in the schemes of the antibiotic prophylaxis was shown to be more efficient vs. the use of the traditional beta-lactam antibiotics.
authors.forename: S D
authors.initials: SD
authors.lastname: Mitrokhin
authors.forename: A A
authors.initials: AA
authors.lastname: Sokolov
authors.forename: V I
authors.initials: VI
authors.lastname: Shirokograd
authors.forename: N P
authors.initials: NP
authors.lastname: Zabaznyĭ
mesh_terms: D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002444:Cefuroxime / Q000008:administration & dosage*; D019818:Clavulanic Acid / Q000008:administration & dosage*; D003428:Cross Infection / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000601:surgery*
chemical_list: D000900:Anti-Bacterial Agents; D019818:Clavulanic Acid; D005578:Fosfomycin; D000658:Amoxicillin; D002444:Cefuroxime