1H magnetic resonance spectroscopy of prostate cancer: biomarkers for tumor characterization.
Proton Magnetic Resonance Spectroscopic Imaging (MRSI) permits a non-invasive assessment of metabolites in the prostate gland. This article reviews the assessment of choline-containing compounds, citrate, and polyamines as markers for prostate tumor detection and aggressiveness.
Zakian
Kristen L
KL
Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, NY, USA. zakiank@mskcc.org
Shukla-Dave
Amita
A
Ackerstaff
Ellen
E
Hricak
Hedvig
H
Koutcher
Jason A
JA
D014408:Biomarkers, Tumor / Q000032:analysis; D002794:Choline / Q000032:analysis; D002951:Citrates / Q000032:analysis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D011073:Polyamines / Q000032:analysis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology
D014408:Biomarkers, Tumor; D002951:Citrates; D011073:Polyamines; D002794:Choline