[Association of disseminated nocardiosis and Kaposi's sarcoma after kidney transplantation].
We report a 40-year-old kidney recipient who developed disseminated nocardiosis associated with cutaneous Kaposi's sarcoma. The withdrawal of immunosuppressive therapy and prolonged antibiotic therapy, including imipenem and trimethoprim-sulfamethoxazole, resulted in a favourable outcome of both disorders. Three years later, graft function remains stable with a complete regression of skin and pulmonary abnormalities. This case report illustrates the predisposing role of immunosuppressive treatment in the occurrence of infectious and neoplastic complications observed after solid-organ transplantation.
Abderrahim
E
E
Service de médecine interne A, laboratoire de pathologie rénale (santé 02), hôpital Charles-Nicolle, 1006 Tunis, Tunisie. abderrahim.ezzeddine@rns.tn
Jbali
H
H
Ounissi
M
M
Hedri
H
H
Bakir
S
S
Ben Abdallah
T
T
Ben Maïz
H
H
Kheder
A
A
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009617:Nocardia Infections / Q000139:chemically induced*; D012514:Sarcoma, Kaposi / Q000139:chemically induced*; D016896:Treatment Outcome; D014295:Trimethoprim / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D007166:Immunosuppressive Agents; D015378:Imipenem; D014295:Trimethoprim