Infectious and inflammatory skin diseases in children with HIV infection and their relation with the immune status--evaluation of 127 patients.
Human immunodeficiency virus infection causes changes in the immune system and disease evolution can be partially measured by levels of T CD4(+) lymphocytes. Knowledge of the chronology of skin disease in relationship to the immune status of the patient may help understand the pathogenesis of AIDS. One hundred twenty-seven children were prospectively evaluated for skin diseases and their relationship to immune status. Immunodeficiency in human immunodeficiency virus-infected children was correlated with infectious dermatoses whereas normal CD4(+) T lymphocyte levels was correlated with diseases mediated by hypersensitivity mechanisms.
Carvalho
Vânia Oliveira
VO
Division of Pediatric Dermatology, Clinical Hospital Paraná's Federal University, Curitiba, Paraná, Brazil. rcarvalho50@hotmail.com
Cruz
Cristina Rodrigues
CR
Marinoni
Leide Parolin
LP
Lima
Hermênio Cavalcante
HC
D001424:Bacterial Infections / Q000276:immunology*; D018791:CD4 Lymphocyte Count; D002648:Child; D002675:Child, Preschool; D003872:Dermatitis / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D016867:Immunocompromised Host; D008297:Male; D011446:Prospective Studies; D012871:Skin Diseases / Q000276:immunology*