title: Applications of chiral allylmetallating agents toward the synthesis of oxygen heterocyles.
abstract: Oxygen heterocycles represent an important structural feature in many biologically active natural products. Consequently, new methods for the stereoselective synthesis of these units are continuously being sought. Allylmetal reagents have emerged as powerful tools in these efforts. This review summarizes some of the recent research on the synthesis of tetrahydrofurans, dihydropyrans, tetrahydropyrans, butyrolactones and oxepanes via allylmetallation reactions.
authors.affiliation: Scripps Florida, Department of Chemistry, 130 Scripps Way #342, Jupiter, Florida 33458, USA.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Bates
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: William R
authors.initials: WR
authors.lastname: Roush
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis; D000498:Allyl Compounds / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry; D005663:Furans / Q000138:chemical synthesis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D010100:Oxygen; D011714:Pyrans / Q000138:chemical synthesis; D012821:Silanes / Q000138:chemical synthesis; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000498:Allyl Compounds; D001897:Boronic Acids; D005663:Furans; D006571:Heterocyclic Compounds; D011714:Pyrans; D012821:Silanes; C511847:allylsilane; D010100:Oxygen