title: Effect of spinal cord stimulation in Type I complex regional pain syndrome with 2 rare severe cutaneous manifestations.
abstract: The authors present the case of a 49-year-old female patient with complex regional pain syndrome-Type I (CRPSI) who was suffering from nonhealing wounds and giant bullae, which dramatically improved after spinal cord stimulation (SCS). The scientific literature concerning severe cutaneous manifestations of CRPS-I and their treatment is reviewed. Nonhealing wounds and bullae are rare manifestations of CRPS-I that are extremely difficult to treat. Immediate improvement of both wounds and bullae after SCS, such as in this case, has not been reported previously in literature. Considering the rapidly progressive nature of these severe skin manifestations, immediate treatment, possibly with SCS, is mandatory.
authors.affiliation: Department of Neurosurgery, Maastricht University Hospital, Maastricht, The Netherlands. kimrijkers@gmail.com
authors.forename: Kim
authors.initials: K
authors.lastname: Rijkers
authors.forename: Jasper
authors.initials: J
authors.lastname: van Aalst
authors.forename: Erkan
authors.initials: E
authors.lastname: Kurt
authors.forename: Marc A
authors.initials: MA
authors.lastname: Daemen
authors.forename: Emile A M
authors.initials: EA
authors.lastname: Beuls
authors.forename: Geert H
authors.initials: GH
authors.lastname: Spincemaille
mesh_terms: D000005:Abdomen; D001768:Blister / Q000209:etiology / Q000628:therapy*; D002574:Cervical Vertebrae; D020878:Device Removal; D004599:Electric Stimulation Therapy / Q000295:instrumentation* / Q000379:methods*; D004567:Electrodes, Implanted; D004867:Equipment Design; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000628:therapy; D008875:Middle Aged; D012019:Reflex Sympathetic Dystrophy / Q000628:therapy*; D012086:Reoperation; D012867:Skin / Q000294:innervation*; D013116:Spinal Cord / Q000503:physiopathology*; D014947:Wounds and Injuries / Q000209:etiology / Q000628:therapy*