Standard automated perimetry and algorithms for monitoring glaucoma progression.
Despite increasingly sophisticated techniques for the computerized analysis of the optic nerve and retinal nerve fiber layer, standard automated perimetry (SAP) is still the primary test for assessing functional damage in glaucoma. Most of the diseases affecting the visual field can be studied analyzing the central visual field with a fixed grid of points set at 6 degrees or at a variable density within central 30 degrees, using a III white target stimulus (program 30/2 or 24/2 Humphrey, G1/G2 or 30/2 Octopus). Although there is lack of a true gold standard for glaucoma, SAP results were the primary endpoint in most of the clinical trials in glaucoma. New thresholding strategies allowed a considerable reduction of examination time without substantial loss of accuracy. Moreover, recent findings on structure-function correlation in glaucoma validate the clinical role of this well-known and widespread method of examination.
Scuderi
G L
GL
University of Rome La Sapienza, S. Andrea Hospital, Via di Grottarossa 1033, 00100 Rome, Italy. gianluca.scuderi@uniroma1.it
Cesareo
M
M
Perdicchi
A
A
Recupero
S M
SM
D000465:Algorithms; D002986:Clinical Trials as Topic; D018450:Disease Progression; D005901:Glaucoma / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D015203:Reproducibility of Results; D058609:Visual Field Tests / Q000295:instrumentation / Q000379:methods; D014794:Visual Fields / Q000502:physiology*