title: Transition-metal-free indirect friedlander synthesis of quinolines from alcohols.
abstract: The synthesis of polysubstituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding 2-aminobenzylic alcohol derivative and either a ketone or alcohol in the presence of a base, without any transition-metal catalyst.
authors.affiliation: Instituto de Síntesis Orgánica and Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Alicante, Apdo. 99, E-03080-Alicante, Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Martínez
authors.forename: Diego J
authors.initials: DJ
authors.lastname: Ramón
authors.forename: Miguel
authors.initials: M
authors.lastname: Yus
mesh_terms: D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D007202:Indicators and Reagents; D007211:Indoles / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D017553:Phosphorus Compounds / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D007211:Indoles; D017553:Phosphorus Compounds; D011804:Quinolines