My, what asthenia you have.
A 59-year-old woman noted intermittent ptosis, diplopia, dysphagia, and proximal muscle weakness for several years. She had a strong family history of myasthenia gravis. Chest computed tomography and sternotomy revealed a micronodular spindle cell thymoma. Electromyography and antibody testing was negative for myasthenia gravis. Genetic testing confirmed a diagnosis of oculopharyngeal muscular dystrophy.
Lee
Michael S
MS
Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota, USA.
Kosmorsky
Gregory S
GS
Cook
James R
JR
Barton
Jason J S
JJ
Briemberg
Hannah R
HR
D001247:Asthenia / Q000175:diagnosis*; D001763:Blepharoptosis / Q000175:diagnosis; D004172:Diplopia / Q000175:diagnosis; D004576:Electromyography; D005260:Female; D006801:Humans; D008875:Middle Aged; D018908:Muscle Weakness / Q000175:diagnosis; D039141:Muscular Dystrophy, Oculopharyngeal / Q000175:diagnosis*; D011859:Radiography; D013934:Thymectomy; D013945:Thymoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery