Synthesis of (+)-DGDP and (-)-7-epialexine.
The partial reduction of electron deficient pyrroles is an extremely versatile method that allows us to prepare substituted pyrrolidines and pyrrolizidines with trans-diol stereochemistry on the five membered ring.
Donohoe
Timothy J
TJ
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK. timothy.donohoe@chem.ox.ac.uk
Cheeseman
Matthew D
MD
O'Riordan
Timothy J C
TJ
Kershaw
Jessica A
JA
D011758:Pyrroles / Q000737:chemistry; D011763:Pyrrolizidine Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D013012:Sorbitol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
C513881:2,5-dideoxy-2,5-imino-D-glucitol; D011758:Pyrroles; D011763:Pyrrolizidine Alkaloids; C059794:australine; C013231:pyrroline; D013012:Sorbitol