[From human genome to individualized medicine].
Advances in the knowledge of our genome, and a deeper understanding of the molecular basis of disease are laying the foundations of Individualised Medicine. This new approach to Medicine seeks to establish a consistent relation between the genetic profile of each individual and the clinical profile of every disease, thereby helping healthcare professionals to individualise treatment for each patient, in order to administrate the right drug at the right dose, while optimising its efficacy and safety. Translational research, Pharmacogenetics, Pharmacogenomics, biomarkers and diagnostic tests are bringing profound change already under way to our healthcare systems, and pose new ethical and social challenges that our legal framework will have to address.
Del Barrio
Jaime
J
Instituto Roche, Madrid, España.
D005826:Genetics, Medical / Q000941:ethics / Q000331:legislation & jurisprudence; D015894:Genome, Human; D006801:Humans; D008511:Medicine / Q000379:methods*