title: Syntheses of tetrahydro-beta-carbolines via a tandem hydroformylation-Pictet-Spengler reaction. Scope and limitations.
abstract: A novel one-pot synthesis of tetrahydro-beta-carboline systems via tandem hydroformylation-Pictet-Spengler reaction starting from olefins and aryl ethylamines is described. This tandem procedure allows fast and convenient synthesis of various substituted tetrahydro-beta-carbolines.
authors.affiliation: Technische Universität Dortmund, Fachbereich Chemie, Organische Chemie I, Otto-Hahn-Str. 6, 44227, Dortmund.
authors.forename: Bojan P
authors.initials: BP
authors.lastname: Bondzic
authors.forename: Peter
authors.initials: P
authors.lastname: Eilbracht
mesh_terms: D000475:Alkenes / Q000737:chemistry; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014363:Tryptamines / Q000737:chemistry; D014364:Tryptophan / Q000737:chemistry
chemical_list: D000475:Alkenes; D002243:Carbolines; D014363:Tryptamines; C030820:tryptamine; C009804:tryptoline; D014364:Tryptophan