title: Nephron sparing surgery using a bipolar radio frequency resection device.
abstract: OBJECTIVE
  We evaluated operative outcomes during nephron sparing surgery using a handheld radio frequency ablation resection device.
  
  
  METHODS
  Patients with a newly diagnosed renal mass who elected treatment were prospectively enrolled in a comparative trial designed to evaluate the usefulness of the handheld HABIB 4X radio frequency ablation device during open nephron sparing surgery. Preoperative variables were determined and patients subsequently underwent open nephron sparing surgery with (group 1) or without (control group 2) the assistance of the radio frequency ablation device. Data were collected on preoperative and postoperative creatinine and hematocrit, estimated operative blood loss, intraoperative and postoperative complications, and pathological outcomes.
  
  
  RESULTS
  A total of 90 patients underwent open nephron sparing surgery with (45) and without (45) the radio frequency ablation device. Mean pathological tumor size was 3.31 and 3.13 cm in groups 1 and 2, respectively (p = 0.49). Mean estimated blood loss was 133.2 and 417.2 cc in groups 1 and 2, respectively (p <0.001). Mean operative time was 83.5 and 97.2 minutes in groups 1 and 2, respectively (p = 0.012). Ten of 45 group 2 patients underwent hilar clamping with hypothermia, while no patients in group 1 underwent hilar clamping. Margins were positive in 1 patient in group 1 (2.2%) and in 2 in group 2 (4.4%). Group 1 complications included postoperative urine leakage in 1 case, which required stent placement. Group 2 complications included 2 cases of urine leakage requiring stent placement, 4 of blood transfusion, 2 of ureteral lacerations, 2 episodes of clot retention and 1 death.
  
  
  CONCLUSIONS
  The handheld radio frequency ablation device can yield a significant benefit during open nephron sparing surgery, namely decreased blood loss and operative time.
authors.affiliation: Division of Urologic Surgery, University of Tennessee Medical Center, Knoxville, Tennessee 37920, USA. wwhite@mc.utmck.edu
authors.forename: Wesley M
authors.initials: WM
authors.lastname: White
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Klein
authors.forename: W Bedford
authors.initials: WB
authors.lastname: Waters
mesh_terms: D000328:Adult; D000368:Aged; D017115:Catheter Ablation / Q000295:instrumentation*; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D009399:Nephrons; D011446:Prospective Studies; D055815:Young Adult