title: New acylides: synthesis of 3-O-[gamma-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives.
abstract: In search of new erythromycin derivatives 3-O-[gamma-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generated at the amino functionality through DCC mediated one-pot three-component reaction in good yields.
authors.affiliation: Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, 226 001 India. pandeydeepa1@yahoo.com
authors.forename: Deepa
authors.initials: D
authors.lastname: Pandey
authors.forename: Wahajul
authors.initials: W
authors.lastname: Haq
authors.forename: Seturam B
authors.initials: SB
authors.lastname: Katti