title: Lemierre's syndrome with fourth nerve palsy.
abstract: Lemierre's syndrome is characterized by acute oropharyngeal infection with secondary internal jugular vein thrombophlebitis and subsequent metastatic infections. The anaerobe Fusobacterium necrophorum is the usual etiologic agent, although other microorganisms, including Streptococcus, Staphylococcus, Enterococcus, Bacteroides, and Lactobacilli, may be present alone or in combination with F. necrophorum. Common sites of metastatic infection include the lungs and joints. Thromboembolic complications, such as septic pulmonary embolism, persistent jugular vein occlusion, hepatic abscesses, and nephropathy, may occur. We report a case of Lemierre's syndrome in a 3-year-old Caucasian boy who subsequently presented with manifestations of a fourth (trochlear) nerve palsy.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Seongmu
authors.initials: S
authors.lastname: Lee
authors.forename: Tina
authors.initials: T
authors.lastname: Rutar
authors.forename: Federico G
authors.initials: FG
authors.lastname: Velez
authors.forename: Arthur L
authors.initials: AL
authors.lastname: Rosenbaum
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D020432:Trochlear Nerve Diseases / Q000175:diagnosis / Q000382:microbiology*; D034363:Viridans Streptococci
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin; D002443:Ceftriaxone