Endoscopic treatment of bleeding gastric varices using large amount of N-butyl-2-cyanoacrylate under fluoroscopic guidance.
OBJECTIVE
We propose the use of fluoroscopic guidance for endoscopic injection of n-butyl-2-cyanoacrylate to treat gastric variceal hemorrhage to achieve placement of the safest quantity of tissue adhesive.


METHODS
Ten patients with gastric varices were treated with n-butyl-2-cyanoacrylate endoscopic injection under fluoroscopic guidance for the purpose of hemostasis or prevention of recurrent bleeding. The glue was infused into the varices in the quantities needed to achieve complete obliteration of the gastric varices.


RESULTS
The median quantity of tissue adhesive required in this series was 6.6 mL. The procedure was initially considered successful in all patients. There were no complications relating to the procedure. The mean duration of follow-up was 20 months.


CONCLUSIONS
Injection of suitable quantities of cyanoacrylate under fluoroscopic guidance seems to be safe and effective for controlling hemorrhagic gastric varices.
Linhares
Marcelo Moura
MM
Department of Surgical Gastroenterology, Federal University of Sao Paulo, EPM, UNIFESP, São Paulo, Brazil. marbet@uol.com.br
Matone
Jacques
J
Matos
Delcio
D
Sakamoto
Flávio Issao
FI
Caetano
Elesiário Marques
EM
Sato
Nélson Yokishito
NY
Herani Filho
Benedito
B
Aramayo
Ana Letícia
AL
Goldenberg
Alberto
A
Lopes-Filho
Gaspar De Jesus
Gde J
D000328:Adult; D000368:Aged; D004659:Enbucrilate / Q000008:administration & dosage*; D004932:Esophageal and Gastric Varices / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D005471:Fluoroscopy; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D016558:Hemostasis, Endoscopic; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D014014:Tissue Adhesives / Q000008:administration & dosage*
D014014:Tissue Adhesives; D004659:Enbucrilate