Infantile hemangiomas: an emerging health issue linked to an increased rate of low birth weight infants.
A total of 420 children with infantile hemangioma (IH) were compared with 353 age-matched controls. Using multivariate logistic regression, low birth weight was the most significant risk factor; for every 500-g decrease in birth weight, the risk of IH increased by 40%. A positive family history also increased the risk of IH (33% vs 15% of controls; P < .001).
Drolet
Beth A
BA
Department of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Swanson
Elizabeth A
EA
Frieden
Ilona J
IJ
D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D006391:Hemangioma / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D008423:Maternal Age; D016017:Odds Ratio; D010372:Pediatrics / Q000379:methods; D012042:Registries; D012044:Regression Analysis; D012307:Risk Factors