Central hypoventilation syndrome after Haemophilus influenzae type b meningitis and herpes infection.
A case of central hypoventilation syndrome was identified in a child with brainstem and cervical cord injury following Haemophilus influenzae type b meningitis and extensive herpes simplex infection. This process resulted in a spastic tetraplegia, and the child continues to require respiratory support. Possible mechanisms of causation are discussed including an evolving, progressive inflammatory or vasculitic process in the setting of transient immunosuppression.
Tirupathi
Sandya
S
Department of Neurosciences, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Webb
David W
DW
Phelan
Ethna
E
Butler
Karina
K
McMenamin
Joseph B
JB
D002675:Child, Preschool; D019741:Haemophilus influenzae type b; D006561:Herpes Simplex / Q000150:complications*; D006801:Humans; D007040:Hypoventilation / Q000382:microbiology* / Q000473:pathology / Q000821:virology*; D007223:Infant; D007238:Infarction / Q000382:microbiology / Q000473:pathology / Q000821:virology; D008279:Magnetic Resonance Imaging; D008297:Male; D008583:Meningitis, Haemophilus / Q000150:complications*; D011149:Pons / Q000473:pathology; D011782:Quadriplegia / Q000382:microbiology / Q000473:pathology / Q000821:virology; D012131:Respiratory Insufficiency / Q000382:microbiology / Q000473:pathology / Q000821:virology; D013116:Spinal Cord / Q000473:pathology