title: Plants as biofactories.
abstract: Cell substrates are a key component of successful vaccine development and throughout the last several decades there has been a dramatic increase in the types of cells available for vaccine production. Nevertheless, there is a continued demand for new and innovative approaches for vaccine development and manufacturing. Recent developments involving cells of insect and plant origin are attracting considerable scientific interest. Here we review vaccine antigen production in plant-based systems as was presented by Dr. Vidadi Yusibov of Fraunhofer USA Center for Molecular Biotechnology at the IABS International Scientific Workshop on NEW CELLS FOR NEW VACCINES II that was held in Wilmington, Delaware on September 17-19, 2007.
authors.affiliation: Fraunhofer USA Center for Molecular Biotechnology, 9 Innovation Way, Suite 200, Newark, DE 19711, USA.
authors.forename: Vadim
authors.initials: V
authors.lastname: Mett
authors.forename: Christine E
authors.initials: CE
authors.lastname: Farrance
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Green
authors.forename: Vidadi
authors.initials: V
authors.lastname: Yusibov
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D000956:Antigens, Viral / Q000737:chemistry; D001419:Bacteria / Q000378:metabolism; D005658:Fungi / Q000378:metabolism; D005822:Genetic Vectors; D006801:Humans; D007313:Insecta; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified; D014481:United States; D022223:Vaccines, Subunit / Q000009:adverse effects / Q000096:biosynthesis* / Q000191:economics / Q000235:genetics; D014614:Vaccines, Synthetic / Q000009:adverse effects / Q000096:biosynthesis* / Q000191:economics / Q000235:genetics; D014765:Viral Vaccines / Q000737:chemistry; D014773:Virology / Q000379:methods / Q000639:trends*
chemical_list: D000956:Antigens, Viral; D022223:Vaccines, Subunit; D014614:Vaccines, Synthetic; D014765:Viral Vaccines