title: Cutaneous pustular manifestations associated with disseminated septic embolism due to a Panton-Valentine leukocidin-producing strain of community-acquired methicillin-resistant Staphylococcus aureus.
abstract: We report a 12-year-old child presented with cutaneous pustular lesions. The lesions are associated with disseminated septic embolism due to Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). The mortality of CA-MRSA sepsis associated with cutaneous findings is high. In areas where CA-MRSA is endemic, empiric treatment of suspected cutaneous manifestations should include antibiotics predictably active against this pathogen.
authors.affiliation: Department of Pediatrics, College of Medicine, Chang Gung University, Chang Gung Children's Hospital, Tauyuan, Taiwan. wct0722@yahoo.com.tw
authors.forename: Chang-Teng
authors.initials: CT
authors.lastname: Wu
authors.forename: Jainn-Jin
authors.initials: JJ
authors.lastname: Lin
authors.forename: Shao-Hsuan
authors.initials: SH
authors.lastname: Hsia
mesh_terms: D016470:Bacteremia / Q000175:diagnosis* / Q000628:therapy; D001427:Bacterial Toxins / Q000097:blood*; D002648:Child; D003131:Combined Modality Therapy; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000628:therapy; D016638:Critical Illness; D018450:Disease Progression; D004636:Emergency Service, Hospital; D005098:Exotoxins / Q000097:blood*; D017809:Fatal Outcome; D006801:Humans; D007956:Leukocidins / Q000097:blood*; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D009102:Multiple Organ Failure; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D011859:Radiography; D013207:Staphylococcal Skin Infections / Q000175:diagnosis* / Q000628:therapy
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin