[Clinical efficacy of buzhong yiqi pill combined with imodium in treating post-operational diarrhea in patients of colonic cancer].
OBJECTIVE
To investigate the clinical efficacy of Buzhong Yiqi Pill (BYP) combined with imodium in treating post-operational diarrhea in patients undergoing colonic cancer surgery.


METHODS
Eighty patients with diarrhea after colorectal cancer surgery were randomized into two groups equally, the control group were treated with imodium (loperamide hydrochloride) and the treatment group treated by BYP combined with imodium. The therapeutic efficacy was analyzed and evaluated comprehensively depending upon a defecation check table developed from the XU Zhong-fa's 5-item 10-integrable system.


RESULTS
After treatment, the improvements of the anal controlling capacity, the defecatory sensation, the frequency of defecation in the treatment group were significantly better than those in the control group (P < 0.01 or P < 0.05). The integral function of defecation in the treatment group was obvionsly improved by the end of treatment when compared with before treatment and the control group (P < 0.01).


CONCLUSIONS
The clinical efficacy of the BYP combined with imodium in treating post-operational diarrhea after colorectal cancer surgery were better than that of imodium alone.
Tu
Xiao-huang
XH
Institute of General Surgery, Fuzhou General Hospital of Nanjing Military Area.
Chen
Zhi-yao
ZY
D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000503:physiopathology / Q000601:surgery*; D003967:Diarrhea / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008139:Loperamide / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy* / Q000503:physiopathology; D055815:Young Adult
D004365:Drugs, Chinese Herbal; D008139:Loperamide