Integrating genomics across drug discovery and development.
The sequencing of the human genome was an exceptional achievement, but it was not an end in itself as it set the foundation for building new knowledge in biology and medicine. The laborious, multifaceted science of drug discovery and development also draws tremendous benefits from mining the human genome and exploiting the large palette of genomic technologies. This article discusses how diverse genomic tools have been used to date and how they will continue to be utilized in the future to impact drug discovery and development. Integrating genomics across drug discovery and development will undoubtedly help to shorten timelines, increase success rates at all stages and ultimately bring the right drugs to the right patients at the right times.
Debouck
Christine
C
Ardennes Biosciences LLC, Wayne, PA 19087, USA. cmdpa1@verizon.net
D000818:Animals; D035843:Biomedical Research / Q000379:methods*; D004195:Disease Models, Animal; D055808:Drug Discovery; D004345:Drug Industry; D042241:Early Diagnosis; D015894:Genome, Human; D023281:Genomics; D016045:Human Genome Project; D006801:Humans; D010597:Pharmacogenetics