Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal.
Palladium on charcoal serves as an efficient and reusable solid supported catalyst for the Sonogashira coupling of aryl chlorides with terminal acetylenes in the presence of a bulky, electron-rich biphenyl type ligand (XPhos), without copper co-catalyst.
Komáromi
Anna
A
Department of Organic Chemistry, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter stny. 1/a, Budapest, Hungary.
Novák
Zoltán
Z