title: The use of complementary and alternative medicine among Chinese women with breast cancer.
abstract: OBJECTIVE
  Using data from the Shanghai Breast Cancer Survival Study (SBCSS), we estimated the prevalence and perceived benefits of complementary and alternative medicine (CAM) and Chinese herbal medicine (CHM), and relevant demographic and clinical factors.
  
  
  METHODS
  This was a cross-sectional cohort study. SUBJECTS/SETTING/LOCATION: Subjects were 5046 women who participated in the SBCSS, conducted in urban Shanghai, China. INTERVENTIONS/OUTCOME MEASURES: Data on CAM use (at least once a week for at least 1 month), patient sociodemographics, and medical history were collected using a structured questionnaire.
  
  
  RESULTS
  The average diagnosis age of participants was 53.5 years. Interviews were completed about 6.5 months after diagnosis. Ninety-seven percent (97%) of participants used CAM therapy after diagnosis. Supplements were the most common type, followed by CHM, and physical activity. Walking was the most popular type of physical activity. Almost all CHM users used CHM as part of their cancer treatment; three quarters reported CHM use for boosting the immune system. About two thirds of women considered CHM effective. Supplement users were more likely to have higher income, higher educational attainment, be married, have undergone or completed radiotherapy, used tamoxifen, have estrogen receptor (ER)-negative/progesterone receptor (PR)-negative cancer, and have menopausal symptoms. CHM use was associated with younger age, higher income, menopausal symptoms, completion of chemotherapy, and past tamoxifen use. Patients with an earlier clinical stage or who had undergone radiotherapy used less CHM. Chemotherapy or radiotherapy and cancer metastasis were positively related to physical activity participation. Current tamoxifen use, ER-/PR- cancer, higher educational attainment, and reporting average or better quality of life were inversely related to exercise participation.
  
  
  CONCLUSIONS
  Given the high prevalence of CAM use in patients with breast cancer and the variety of types of CAM, more research is needed to determine the impact of CAM's effectiveness and safety and interaction with conventional cancer treatment on breast cancer survival.
authors.affiliation: Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt School of Medicine and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chen
authors.forename: Kai
authors.initials: K
authors.lastname: Gu
authors.forename: Ying
authors.initials: Y
authors.lastname: Zheng
authors.forename: Wei
authors.initials: W
authors.lastname: Zheng
authors.forename: Wei
authors.initials: W
authors.lastname: Lu
authors.forename: Xiao Ou
authors.initials: XO
authors.lastname: Shu
mesh_terms: D000328:Adult; D000368:Aged; D001294:Attitude to Health; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000628:therapy*; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003131:Combined Modality Therapy; D000529:Complementary Therapies / Q000523:psychology / Q000706:statistics & numerical data*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009042:Motivation; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D015995:Prevalence; D011788:Quality of Life; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D016387:Women's Health