Clear cell hidradenocarcinoma developing in pacemaker pocket.
An octagenerian woman developed clear cell hidradenocarcinoma, a rare neoplasm of eccrine sweat gland origin, 4 years following pacemaker implantation in her right lateral chest. The tumor immunohistochemically mimicked a metastatic lobular breast carcinoma, for example, strongly positive estrogen, weakly positive progesterone, and weakly reactive mammoglobin. A complete surgical excision of the tumor was complemented with ipsilateral dissection of involved adjacent axillary lymph nodes. Recommended irradiation was refused by the patient. Retrospective 3-year mammogram review, 2-year postsurgery follow-up, and complete postmortem evaluation failed to prove a primary breast malignancy or other metastatic lesion elsewhere.
Reyes
Cesar V
CV
Department of Clinical Laboratories, Morris Hospital and Hines VA Hospital, Morris, Illinois, USA. creyes@morrishospital.org
D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D005549:Foreign-Body Reaction / Q000175:diagnosis* / Q000209:etiology*; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010138:Pacemaker, Artificial / Q000009:adverse effects*