Rhino-orbital zygomycosis secondary to Rhizopus oryzae in a renal transplant recipient successfully treated with liposomal amphotericin B.
Rhino-orbital zygomycosis is usually an aggressive, fulminant and, at times, fatal disease that requires urgent medical and surgical treatment. We report a case of rhino-orbital zygomycosis caused by Rhizopus oryzae that developed in a 41-year-old male renal transplant recipient. He was diagnosed in the early post transplant period after anti-rejection therapy. The infection was successfully managed with liposomal amphotericin B and functional endoscopic sinus surgery.
Yassin
M A
MA
Hematology Division, AL Amal Hospital, P.O. Box 3050 Doha, Qatar. yassin160@yahoo.co.uk
Taj-Aldeen
S J
SJ
Khan
F Y
FY
Errayes
M
M
Aref
E
E
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009668:Nose Diseases / Q000188:drug therapy* / Q000209:etiology; D009916:Orbital Diseases / Q000188:drug therapy* / Q000209:etiology; D012233:Rhizopus / Q000302:isolation & purification*; D012307:Risk Factors; D020096:Zygomycosis / Q000188:drug therapy*
D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B