Patterning stem cell differentiation.
Regulation of cell differentiation and assembly remains a fundamental question in developmental biology. Now, a report from the Chen laboratory (Ruiz and Chen, 2008) describes an approach that represents a major step toward a more profound understanding of the geometric-force control of stem cell differentiation.
Vunjak-Novakovic
Gordana
G
Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Avenue, Mail Code 8904, New York, NY 10027, USA. gv2131@columbia.edu
D050156:Adipogenesis / Q000502:physiology*; D019521:Body Patterning; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D019070:Cell Lineage; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D040542:Mechanotransduction, Cellular; D010012:Osteogenesis / Q000502:physiology*; D012038:Regeneration; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism; D013314:Stress, Mechanical; D023822:Tissue Engineering