title: Hereditary spherocytosis with high fetal hemoglobin: an interesting case.
abstract: Raised Hb F is occasionally found in stress erythropoiesis associated with hemolytic anemias. In hereditary spherocytosis (HS), elevation of Hb F by 2-5% may be seen but Hb F in the range of 10-20% has not been reported. We present an interesting case of a child, initially presenting with high Hb F, who showed a spontaneous and progressive decline, and was subsequently diagnosed to have HS with raised fetal hemoglobin (Hb F) using an eosin-5-maleimide flow cytometric test.
authors.affiliation: Department of Hematology, All India Institute of Medical Sciences, New Delhi, India. rakhee_kar@rediffmail.com
authors.forename: Rakhee
authors.initials: R
authors.lastname: Kar
authors.forename: Renu
authors.initials: R
authors.lastname: Saxena
authors.forename: Hara P
authors.initials: HP
authors.lastname: Pati
mesh_terms: D002675:Child, Preschool; D005319:Fetal Hemoglobin / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D008297:Male; D013103:Spherocytosis, Hereditary / Q000378:metabolism*
chemical_list: D005319:Fetal Hemoglobin