title: Prenatal diagnosis of dextrotransposition of the great arteries.
abstract: Dextrotransposition of the great arteries (DTGA) is a common cardiac cause of cyanosis in newborn infants that can cause acidosis and death within a short period of time unless there is a large atrial-level shunt or a patent ductus arteriosus. Here, we report a case of prenatal diagnosis of DTGA at 24+1 gestational weeks. In a tilted 4-chamber view, the pulmonary trunk branched to the left and the right pulmonary, with its root connected to the left ventricle outflow tract. In the short-axis view, the pulmonary trunk was shown to be parallel with the ascending aortic root. Cesarean section was performed due to the nonreassuring fetal status at 38+5 gestational weeks. The male neonate appeared to have mild cyanotic symptoms and weighed 3,108 g. Apgar scores were 8 and 9 at 1 and 5 minutes, respectively. Neonatal echocardiography was performed immediately after birth and the findings confirmed DTGA associated with atrial septal defect secundum. Postnatally, angiography confirmed the echocardiographic diagnosis of DTGA with a large atrial septal defect secundum and a large patent ductus arteriosus. Jatene arterial switch operation and atrial septal defect closure with Gore-Tex patch were performed. The neonate withstood the operation well and was discharged 27 days after birth weighing 2,950 g and in a stable condition. Prenatal diagnosis of DTGA can greatly aid to prepare the patient's family and the surgeon and significantly improve the outcome of complex heart disease in the neonatal period.
authors.affiliation: Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan, ROC. jhhung@tzuchi.com.tw
authors.forename: Jeng-Hsiu
authors.initials: JH
authors.lastname: Hung
authors.forename: Pi-Tao
authors.initials: PT
authors.lastname: Huang
authors.forename: Zen-Chung
authors.initials: ZC
authors.lastname: Weng
authors.forename: Chih-Yao
authors.initials: CY
authors.lastname: Chen
authors.forename: Kuan-Chong
authors.initials: KC
authors.lastname: Chao
authors.forename: Ming-Jie
authors.initials: MJ
authors.lastname: Yang
authors.forename: Jamie
authors.initials: J
authors.lastname: Hung
mesh_terms: D000328:Adult; D000792:Angiography; D004452:Echocardiography; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014188:Transposition of Great Vessels / Q000175:diagnosis*