title: Endoscopic treatment of bleeding gastric varices using large amount of N-butyl-2-cyanoacrylate under fluoroscopic guidance.
abstract: OBJECTIVE
  We propose the use of fluoroscopic guidance for endoscopic injection of n-butyl-2-cyanoacrylate to treat gastric variceal hemorrhage to achieve placement of the safest quantity of tissue adhesive.
  
  
  METHODS
  Ten patients with gastric varices were treated with n-butyl-2-cyanoacrylate endoscopic injection under fluoroscopic guidance for the purpose of hemostasis or prevention of recurrent bleeding. The glue was infused into the varices in the quantities needed to achieve complete obliteration of the gastric varices.
  
  
  RESULTS
  The median quantity of tissue adhesive required in this series was 6.6 mL. The procedure was initially considered successful in all patients. There were no complications relating to the procedure. The mean duration of follow-up was 20 months.
  
  
  CONCLUSIONS
  Injection of suitable quantities of cyanoacrylate under fluoroscopic guidance seems to be safe and effective for controlling hemorrhagic gastric varices.
authors.affiliation: Department of Surgical Gastroenterology, Federal University of Sao Paulo, EPM, UNIFESP, São Paulo, Brazil. marbet@uol.com.br
authors.forename: Marcelo Moura
authors.initials: MM
authors.lastname: Linhares
authors.forename: Jacques
authors.initials: J
authors.lastname: Matone
authors.forename: Delcio
authors.initials: D
authors.lastname: Matos
authors.forename: Flávio Issao
authors.initials: FI
authors.lastname: Sakamoto
authors.forename: Elesiário Marques
authors.initials: EM
authors.lastname: Caetano
authors.forename: Nélson Yokishito
authors.initials: NY
authors.lastname: Sato
authors.forename: Benedito
authors.initials: B
authors.lastname: Herani Filho
authors.forename: Ana Letícia
authors.initials: AL
authors.lastname: Aramayo
authors.forename: Alberto
authors.initials: A
authors.lastname: Goldenberg
authors.forename: Gaspar De Jesus
authors.initials: Gde J
authors.lastname: Lopes-Filho
mesh_terms: D000328:Adult; D000368:Aged; D004659:Enbucrilate / Q000008:administration & dosage*; D004932:Esophageal and Gastric Varices / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D005471:Fluoroscopy; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D016558:Hemostasis, Endoscopic; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D014014:Tissue Adhesives / Q000008:administration & dosage*
chemical_list: D014014:Tissue Adhesives; D004659:Enbucrilate