title: Dorsal corporectomy in a Ewing sarcoma situated in the pedicle of the L5 vertebral body.
abstract: The clinical case of a 34-year-old patient is presented who was diagnosed with Ewing sarcoma in the right pedicle of the L5 vertebral body on the basis of persisting dorsolumbar pain. Staging examinations including CT scan of the thorax and abdomen as well as bone scintigraphy were inconspicuous. The patient underwent 6 cycles of neoadjuvant chemotherapy (VIDE, similar to Euro Ewing 99). Presurgically, embolisation of the L4 and L5 vertebral bodies was performed on both sides. The tumour was removed via a dorsal approach with corporectomy of L5 and resection of the right nerve root of L5. The defect was bridged by a titanium cage filled with bone cement; a dorsal L4-S1 instrumentation was performed. Early postoperative X-rays showed a screw dislocation in S1, making a revision intervention and screw replacement necessary. For additional fixation, S2 was instrumented. Histopathology classified the tissue samples as containing no active tumour cells. Surgery was followed by additional chemotherapy. The patient has remained free of recurrence until now. The aim of this case report is to call attention to the unusual site of the Ewing sarcoma as well as to discuss therapy options, especially dorsal corporectomy, and the prognosis together with a review of the most current literature.
authors.affiliation: Department of Orthopedic Surgery, Universitiy of Cologne, Köln, Germany. marc.roellinghoff@gmx.de
authors.forename: M
authors.initials: M
authors.lastname: Röllinghoff
authors.forename: M
authors.initials: M
authors.lastname: Koriller
authors.forename: R
authors.initials: R
authors.lastname: Sobottke
authors.forename: K-S
authors.initials: KS
authors.lastname: Delank
authors.forename: P
authors.initials: P
authors.lastname: Eysel
mesh_terms: D000328:Adult; D001863:Bone Screws; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006801:Humans; D017116:Low Back Pain / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures; D011878:Radiotherapy; D012512:Sarcoma, Ewing / Q000601:surgery* / Q000628:therapy; D013125:Spinal Neoplasms / Q000601:surgery* / Q000628:therapy; D013126:Spinal Nerve Roots / Q000601:surgery; D013131:Spine / Q000601:surgery*; D014057:Tomography, X-Ray Computed