[Influence of granulocytic colony-stimulating factor (G-CSF) on reparative osteogenesis].
The effect of recombinant G-CSF (50 mg/day for 3 days) on reparative osteogenesis in rats was studied on the model of induced osteogenesis after resection of a tibial fragment resection. Reparative processes in the bone tissue were estimated by histological picture and activity of serum alkaline phosphatase. The conclusion is made that G-CSF inhibits reparative osteogenesis.
Bazarnyĭ
V V
VV
Krokhina
N B
NB
Isaĭkin
A I
AI
Tikhonina
E A
EA
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D008297:Male; D010012:Osteogenesis / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D011994:Recombinant Proteins
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor