Radiopacity and histological assessment of Portland cement plus bismuth oxide.
OBJECTIVE
The present study evaluated the subcutaneous connective tissue reactions and the radiopacity of MTA, Portland cement (PC), and Portland cement plus bismuth oxide (BO).


METHODS
Forty rats were divided into 5 groups (n = 8 per group): A1: Control (empty capsule); A2: Pro-Root MTA; A3: PC; A4: PC + BO 1:1; and A5: PC + BO 2:1. Polyethylene tubes were filled with the test materials and standardized radiographic images were taken. Histological evaluation was done after 7 and 60 days. Student t test and Fisher's test were used in the statistical analysis (P < .05).


RESULTS
The radiopacity of the materials were in decreasing order: A2 > A4 > A5 > A3. No differences were found for the tissue response in the 2 experimental periods. A positive correlation between BO concentration and radiopacity of PC was determined.


CONCLUSIONS
The histological evaluation suggests that all studied materials were biocompatible at 7 and 60 days.
Coutinho-Filho
Tauby
T
Department of Endodontics, Rio de Janeiro State University, Rio de Janeiro, Brazil.
De-Deus
Gustavo
G
Klein
Leila
L
Manera
Gisele
G
Peixoto
Carla
C
Gurgel-Filho
Eduardo Diogo
ED
D017607:Aluminum Compounds / Q000737:chemistry / Q000633:toxicity; D000818:Animals; D001729:Bismuth / Q000633:toxicity; D017610:Calcium Compounds / Q000737:chemistry / Q000633:toxicity; D003238:Connective Tissue / Q000187:drug effects; D003287:Contrast Media; D003738:Dental Cements / Q000737:chemistry / Q000633:toxicity*; D004338:Drug Combinations; D007249:Inflammation / Q000139:chemically induced; D008297:Male; D010087:Oxides / Q000737:chemistry / Q000633:toxicity; D051381:Rats; D012387:Root Canal Filling Materials / Q000737:chemistry / Q000633:toxicity*; D017640:Silicates / Q000737:chemistry / Q000633:toxicity; D040521:Subcutaneous Tissue / Q000187:drug effects
D017607:Aluminum Compounds; D017610:Calcium Compounds; D003287:Contrast Media; D003738:Dental Cements; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C472247:accelerated Portland cement; C086631:mineral trioxide aggregate; C033301:bismuth oxide; D001729:Bismuth