Reliability of TMS motor evoked potentials in quadriceps of subjects with chronic hemiparesis after stroke.
Transcranial magnetic stimulation (TMS) non-invasively measures excitability of central motor pathways in humans and is used to characterize neuroplasticity after stroke. Using TMS to index lower extremity neuroplasticity after gait rehabilitation requires test-retest reliability. This study assesses the reliability of TMS-derived variables measured at bilateral quadriceps of chronic hemiparetic stroke survivors. Results support using measures of both paretic and nonparetic motor threshold, motor evoked potential (MEP) latencies; and nonparetic MEP amplitudes. Implications for longitudinal research are discussed.
Wheaton
Lewis A
LA
Department of Veterans Affairs and Veterans Affairs Medical Center Baltimore Geriatrics Research, Education and Clinical Center (GRECC), Baltimore, MD, USA.
Villagra
Federico
F
Hanley
Daniel F
DF
Macko
Richard F
RF
Forrester
Larry W
LW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004558:Electric Stimulation / Q000379:methods; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D005684:Gait / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010291:Paresis / Q000209:etiology / Q000473:pathology* / Q000534:rehabilitation; D052097:Quadriceps Muscle / Q000503:physiopathology*; D020127:Recovery of Function; D015203:Reproducibility of Results; D020521:Stroke / Q000150:complications; D050781:Transcranial Magnetic Stimulation / Q000379:methods*