title: Labdane diterpenes from the rhizomes of Hedychium coronarium.
abstract: A new labdane diterpenoid, (E)-labda-8(17),12-dien-15,16-olide (1) together with eight known compounds, coronarin D (2), coronarin D methyl ether (3), coronarin D ethyl ether (4), isocoronarin D (5), coronarin B (6), labda-8(17),11,13-trien-15,16-olide (7), (E)-labda-8(17),12-diene-15,16-dial (8) and 16-hydroxylabda-8(17),11,13-trien-15,16-olide (9), are isolated from the rhizomes of Hedychium coronarium. Compounds 2-4, 5 and 9 are isolated as mixtures of C-15, C-14 and C-16 epimers, respectively. Their structures are determined on the basis of their spectroscopic data. The epimeric mixtures of 2 and 3 have not been reported before. Some of them were evaluated for their cytotoxicity.
authors.affiliation: Chulabhorn Research Institute, Bangkok 10210, Thailand.
authors.forename: Nitirat
authors.initials: N
authors.lastname: Chimnoi
authors.forename: Somchai
authors.initials: S
authors.lastname: Pisutjaroenpong
authors.forename: Lukana
authors.initials: L
authors.lastname: Ngiwsara
authors.forename: Decha
authors.initials: D
authors.lastname: Dechtrirut
authors.forename: Daranee
authors.initials: D
authors.lastname: Chokchaichamnankit
authors.forename: Nisachon
authors.initials: N
authors.lastname: Khunnawutmanotham
authors.forename: Chulabhorn
authors.initials: C
authors.lastname: Mahidol
authors.forename: Supanna
authors.initials: S
authors.lastname: Techasakul
mesh_terms: D002855:Chromatography, Thin Layer; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D030521:Zingiberaceae / Q000737:chemistry*
chemical_list: D004224:Diterpenes