title: [Autopsy of a suspected venous circulatory disturbance localized in the medulla oblongata and upper cervical cord accompanied by an aneurysm].
abstract: We describe an autopsied case of an 86-year-old woman who presented with acute tetraparesis, bulbar palsy, and respiratory insufficiency. MRI showed a T2 hyperintensity lesion in the medulla oblongata and C1 and C2 level cervical cord, and an unruptured aneurysm in the left posterior inferior cerebellar artery. With an initial diagnosis of Bickerstaffs brainstem encephalitis, we started corticosteroid therapy. Initially, the corticosteroid treatment gradually improved her general condition; however, about two weeks later she died of an acute respiratory insufficiency. From the postmortem pathological examination, we considered a venous circulatory disturbance of the medulla oblongata and upper cervical cord. No arteriovenous shunt was found in the intramedulla and the medulla oblongata was partially compressed on the left side by an unruptured aneurysm. However, neither inflammatory nor malignant cells were found in the lesion. What caused the venous circulatory disturbance was unclear, but the dural arteriovenous fistula could have been responsible. Our case suggested that venous circulatory disturbances accompanied with an aneurysm need rapid consideration by angiography followed by intervention.
authors.affiliation: Department of Neurology, Japan Labour Health and Welfare Organization, Kyusyu Rosai Hospital.
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Masaki
authors.forename: Masaharu
authors.initials: M
authors.lastname: Ohno
authors.forename: Hironobu
authors.initials: H
authors.lastname: Maeda
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Hamada
authors.forename: Toru
authors.initials: T
authors.lastname: Iwaki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tomoda
mesh_terms: D000369:Aged, 80 and over; D001344:Autopsy; D002561:Cerebrovascular Disorders / Q000473:pathology*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications*; D008526:Medulla Oblongata / Q000098:blood supply*; D009333:Neck; D013116:Spinal Cord / Q000098:blood supply*