title: Modified aortic cannulation for cardiopulmonary bypass in neonatal piglet model.
abstract: Animal models are still essential for studying effects of cardiopulmonary bypass. We describe modifications in cannulation technique for a neonatal piglet model, which may also serve as an "everyday" technique in congenital cardiac surgery (age of animals <7 days; mean body weight 2.9 +/- 0.5 kg). Surgical approach through median sternotomy and cardiopulmonary bypass was established by cannulating right atrium and ascending aorta with a modified aortic root cannula. Left ventricular venting was performed placing a cannula into the apex and connecting this to the venous drainage line. The described technique has been applied in 19 cases, all but one were without technical problems.
authors.affiliation: Department of Thoracic, Cardiac, and Vascular Surgery, University of Goettingen, Goettingen, Germany. theodor.tirilomis@med.uni-goettingen.de
authors.forename: Theodor
authors.initials: T
authors.lastname: Tirilomis
authors.forename: David
authors.initials: D
authors.lastname: Paz
authors.forename: Lars
authors.initials: L
authors.lastname: Nolte
authors.forename: Friedrich A
authors.initials: FA
authors.lastname: Schoendube
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001011:Aorta / Q000473:pathology / Q000601:surgery*; D006328:Cardiac Catheterization / Q000379:methods*; D002315:Cardiopulmonary Bypass / Q000379:methods*; D005240:Feasibility Studies; D006325:Heart Atria / Q000473:pathology / Q000601:surgery*; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery; D023421:Models, Animal; D013552:Swine