HGVbaseG2P: a central genetic association database.
The Human Genome Variation database of Genotype to Phenotype information (HGVbaseG2P) is a new central database for summary-level findings produced by human genetic association studies, both large and small. Such a database is needed so that researchers have an easy way to access all the available association study data relevant to their genes, genome regions or diseases of interest. Such a depository will allow true positive signals to be more readily distinguished from false positives (type I error) that fail to consistently replicate. In this paper we describe how HGVbaseG2P has been constructed, and how its data are gathered and organized. We present a range of user-friendly but powerful website tools for searching, browsing and visualizing G2P study findings. HGVbaseG2P is available at http://www.hgvbaseg2p.org.
Thorisson
Gudmundur A
GA
Department of Genetics, University of Leicester, University Road, Leicester, LE1 7RH, UK.
Lancaster
Owen
O
Free
Robert C
RC
Hastings
Robert K
RK
Sarmah
Pallavi
P
Dash
Debasis
D
Brahmachari
Samir K
SK
Brookes
Anthony J
AJ
D003196:Computer Graphics; D030541:Databases, Genetic; D014644:Genetic Variation; D015894:Genome, Human; D055106:Genome-Wide Association Study; D005838:Genotype; D006801:Humans; D010641:Phenotype; D012984:Software