title: [Influence of granulocytic colony-stimulating factor (G-CSF) on reparative osteogenesis].
abstract: The effect of recombinant G-CSF (50 mg/day for 3 days) on reparative osteogenesis in rats was studied on the model of induced osteogenesis after resection of a tibial fragment resection. Reparative processes in the bone tissue were estimated by histological picture and activity of serum alkaline phosphatase. The conclusion is made that G-CSF inhibits reparative osteogenesis.
authors.forename: V V
authors.initials: VV
authors.lastname: Bazarnyĭ
authors.forename: N B
authors.initials: NB
authors.lastname: Krokhina
authors.forename: A I
authors.initials: AI
authors.lastname: Isaĭkin
authors.forename: E A
authors.initials: EA
authors.lastname: Tikhonina
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D008297:Male; D010012:Osteogenesis / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D011994:Recombinant Proteins
chemical_list: D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor