Antimicrobial resistance of Campylobacter coli isolates from swine.
Eighty-three swine isolates of Campylobacter coli were tested for mechanisms underlying resistance to nalidixic acid, ciprofloxacin, erythromycin and tetracycline. Four isolates harbored class 1 integrons but none carried class 2 and 3 integrons. Most of the tetracycline-resistant isolates (97%) possessed tet(O). A Thr-86-Ile substitution in GyrA and an A-2230-G mutation in 23S rRNA were the main resistance mechanisms for quinolones and erythromycin, respectively.
Ekkapobyotin
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C
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Padungtod
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Chuanchuen
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R
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002169:Campylobacter Infections / Q000188:drug therapy / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D017000:Campylobacter coli / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D015169:Colony Count, Microbial; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005516:Food Microbiology; D006801:Humans; D032023:Integrons; D008460:Meat / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D009154:Mutation; D012338:RNA, Ribosomal, 23S / Q000235:genetics; D013045:Species Specificity; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy* / Q000382:microbiology / Q000635:transmission; D015047:Zoonoses
D000900:Anti-Bacterial Agents; D012338:RNA, Ribosomal, 23S