title: Complications of percutaneous transhepatic biliary drainage in patients with dilated and nondilated intrahepatic bile ducts.
abstract: Percutaneous transhepatic biliary drainage (PTBD) have been described as an effective technique to obtain biliary access. Between January 1996 and December 2006, a total of 419 consecutive patients with endoscopically inaccessible bile ducts underwent PTBD. The current retrospective study evaluated success and complication rates of this invasive technique. PTBD was successful in 410/419 patients (97%). The success rate was equal in patients with dilated and nondilated bile ducts (p=0.820). In 39/419 patients (9%) procedure related complications could be observed. Major complications occurred in 17/419 patients (4%). Patients with nondilated intrahepatic bile ducts had significantly higher complication rates compared to patients with dilated intrahepatic bile ducts (14.5% vs. 6.9%, respectively [p=0.022]). Procedure related deaths were observed in 3 patients (0.7%). In conclusion, percutaneous transhepatic biliary drainage is an effective procedure in patients with dilated and nondilated intrahepatic bile ducts. However, patients with nondilated intrahepatic bile ducts showed a higher risk for procedure related complications.
authors.affiliation: Department of Gastroenterology, Technical University of Munich, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Weber
authors.forename: Jochen
authors.initials: J
authors.lastname: Gaa
authors.forename: Bogdan
authors.initials: B
authors.lastname: Rosca
authors.forename: Peter
authors.initials: P
authors.lastname: Born
authors.forename: Bruno
authors.initials: B
authors.lastname: Neu
authors.forename: Roland M
authors.initials: RM
authors.lastname: Schmid
authors.forename: Christian
authors.initials: C
authors.lastname: Prinz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001653:Bile Ducts, Intrahepatic / Q000601:surgery*; D002404:Catheterization; D002779:Cholestasis / Q000175:diagnosis* / Q000601:surgery*; D004108:Dilatation, Pathologic; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000175:diagnosis* / Q000209:etiology*; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome