A unique case of collagenous colitis presenting as protein-losing enteropathy successfully treated with prednisolone.
A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99mTc-human serum albumin scintigraphy. Collagenous colitis associated with protein-losing enteropathy (PLE) without small bowel disease was diagnosed. Prednisolone treatment ameliorated diarrhea and hypoproteinemia. Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia for appropriate management.
Sano
Soichi
S
Department of Internal Medicine, Osaka City General Hospital, 2-13-22, Miyakojima-ku, Osaka 534-0021, Japan.
Yamagami
Keiko
K
Tanaka
Ayako
A
Nishio
Minako
M
Nakamura
Tomoyuki
T
Kubo
Yuki
Y
Inoue
Takeshi
T
Ueda
Wataru
W
Okawa
Kiyotaka
K
Yoshioka
Katsunobu
K
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D046729:Colitis, Collagenous / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use*; D011504:Protein-Losing Enteropathies / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D011239:Prednisolone