title: Cellular distribution of okadaic acid in the digestive gland of Mytilus galloprovincialis (Lamarck, 1819).
abstract: The distribution of okadaic acid between the digestive and the secretory cells of the digestive gland of Mytilus galloprovincialis was studied for the main purpose of determining if they might be responsible for the two-compartment depuration kinetics found in previous studies. The two cell types did not accumulate okadaic acid to the same degree. However, the concentrations found in each cellular type were not consistent with those expected from the output of the two-compartment depuration model, suggesting that a mechanism other that the differential accumulation in cellular types is involved. Binding to some yet undetermined cellular components is suggested.
authors.affiliation: Centro de Investigacións Mariñas (CIMA), Pedras de Corón, s/n. Apdo. 13, 36620 Vilanova de Arousa (Pontevedra), Spain.
authors.forename: Araceli E
authors.initials: AE
authors.lastname: Rossignoli
authors.forename: Juan
authors.initials: J
authors.lastname: Blanco
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004064:Digestive System / Q000166:cytology / Q000378:metabolism; D008387:Marine Toxins / Q000378:metabolism; D008954:Models, Biological; D049878:Mytilus / Q000378:metabolism*; D019319:Okadaic Acid / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D014018:Tissue Distribution
chemical_list: D008387:Marine Toxins; D019319:Okadaic Acid