title: 1H magnetic resonance spectroscopy of prostate cancer: biomarkers for tumor characterization.
abstract: Proton Magnetic Resonance Spectroscopic Imaging (MRSI) permits a non-invasive assessment of metabolites in the prostate gland. This article reviews the assessment of choline-containing compounds, citrate, and polyamines as markers for prostate tumor detection and aggressiveness.
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, NY, USA. zakiank@mskcc.org
authors.forename: Kristen L
authors.initials: KL
authors.lastname: Zakian
authors.forename: Amita
authors.initials: A
authors.lastname: Shukla-Dave
authors.forename: Ellen
authors.initials: E
authors.lastname: Ackerstaff
authors.forename: Hedvig
authors.initials: H
authors.lastname: Hricak
authors.forename: Jason A
authors.initials: JA
authors.lastname: Koutcher
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002794:Choline / Q000032:analysis; D002951:Citrates / Q000032:analysis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D011073:Polyamines / Q000032:analysis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D002951:Citrates; D011073:Polyamines; D002794:Choline