Effects of rice bran oil enriched with n-3 PUFA on liver and serum lipids in rats.
Lipase-catalyzed interesterification was used to prepare different structured lipids (SL) from rice bran oil (RBO) by replacing some of the fatty acids with alpha-linolenic acid (ALA) from linseed oil (LSO) and n-3 long chain polyunsaturated fatty acids (PUFA) from cod liver oil (CLO). In one SL, the ALA content was 20% whereas in another the long chain n-3 PUFA content was 10%. Most of the n-3 PUFA were incorporated into the sn-1 and sn-3 positions of triacylglycerol. The influence of SL with RBO rich in ALA and EPA + DHA was studied on various lipid parameters in experimental animals. Rats fed RBO showed a decrease in total serum cholesterol by 10% when compared to groundnut oil (GNO). Similarly structured lipids with CLO and LSO significantly decreased total serum cholesterol by 19 and 22% respectively compared to rice bran oil. The serum TAGs level of rats fed SLs and blended oils were also significantly decreased by 14 and 17% respectively compared to RBO. Feeding of an n-3 PUFA rich diet resulted in the accumulation of long chain n-3 PUFA in various tissues and a reduction in the long chain n-6 PUFA. These studies indicate that the incorporation of ALA and EPA + DHA into RBO can offer health benefits.
Chopra
Rajni
R
Department of Foods and Nutrition, Institute of Home Economics, University of Delhi, F-4, New Delhi, 110017, India.
Sambaiah
Kari
K
D000273:Adipose Tissue / Q000378:metabolism; D000821:Animal Feed; D000818:Animals; D001835:Body Weight; D015525:Fatty Acids, Omega-3 / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D012275:Oryza / Q000033:anatomy & histology / Q000378:metabolism*; D010938:Plant Oils / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D015525:Fatty Acids, Omega-3; D010938:Plant Oils