Tooth extraction socket healing in pediatric patients treated with intravenous pamidronate.
Osteonecrosis of the jaw (ONJ) has been described as a complication of bisphosphonate therapy in adults. In the present study, we did not find a case of ONJ among 278 pediatric patients who had received intravenous pamidronate during childhood or adolescence.
Chahine
Carol
C
From the Faculty of Dentistry, Division of Oral and Maxillofacial Surgery, Montréal, Québec, Canada.
Cheung
Moira S
MS
Head
Timothy W
TW
Schwartz
Stéphane
S
Glorieux
Francis H
FH
Rauch
Frank
F
D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D004164:Diphosphonates / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D007571:Jaw Diseases / Q000628:therapy*; D008297:Male; D010020:Osteonecrosis / Q000628:therapy*; D000077268:Pamidronate; D014081:Tooth Extraction / Q000009:adverse effects*
D000893:Anti-Inflammatory Agents; D004164:Diphosphonates; D000077268:Pamidronate