Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study.
OBJECTIVE
To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka.


METHODS
A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant.


RESULTS
The prevalence of XFS was estimated to be 1.1% (95% CI 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p<0.001), increasing intraocular pressure (odds ratio 1.2; 95% CI 1.09 to 1.27; p<0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47 to 2.51; p<0.001), visual impairment (odds ratio 9.72; 95% CI 3.01 to 31.44; p<0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14 to 13.16; p = 0.030).


CONCLUSIONS
XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.
Rudkin
A K
AK
South Australian Institute of Ophthalmology, Adelaide, 5000, South Australia, Australia. adam@rudkin.com.au
Edussuriya
K
K
Sennanayake
S
S
Senaratne
T
T
Selva
D
D
Sullivan
T R
TR
Casson
R J
RJ
D000328:Adult; D000367:Age Factors; D000368:Aged; D001699:Biometry; D003430:Cross-Sectional Studies; D018450:Disease Progression; D017889:Exfoliation Syndrome / Q000150:complications / Q000453:epidemiology*; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000453:epidemiology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000453:epidemiology*; D015995:Prevalence; D012423:Rural Health; D013188:Sri Lanka / Q000453:epidemiology