Biliary complications after 52 adult living donor liver transplantations: a single-center experience.
OBJECTIVE
The incidence of biliary complications after adult living donor liver transplantation (ALDLT) are still high even though various devices have been reported to overcome them.


METHODS
From October 2000 to April 2007, we performed 52 ALDLTs which included 15 ABO-incompatible grafts. Median follow-up was 565 days. In 49 procedures, we used duct-to-duct anastmosis with a stent inserted in the recipient duct and out through the common bile duct wall as an external stent, and in 3 procedures, we used duct-to-jejunostomy anastomosis. We investigated postoperative biliary complications and their management.


RESULTS
Forty-four patients received right lobe grafts and 8 received left lobe grafts. Among patients in whom duct-to-duct anastomosis was used, nine (20.5%) developed biliary complications including bile leakage in five and biliary strictures in four. All bile leakage was treated with reoperation. Three biliary strictures were treated with stent placement, and one biliary stricture was treated with magnetic compression anastomosis. Among the three patients in whom duct-to-jejunostomy was used, two (66.7%) had bile leakage and stricture, respectively. Two of four ABO-incompatible patients (50%) had hepatic artery thrombosis with biliary complications, a high incidence.


CONCLUSIONS
In our series of ABO-incompatible patients undergoing ALDLT, those who developed hepatic artery thrombosis exhibited a high incidence of biliary complications.
Iwamoto
H
H
5th Department of Surgery, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan. hitoiwa@tokyo-med.ac.jp
Hama
K
K
Nakamura
Y
Y
Osamu
K
K
Yokoyama
T
T
Kihara
Y
Y
Ashizawa
T
T
Niido
T
T
Matsuno
N
N
Nagao
T
T
D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D001652:Bile Ducts / Q000601:surgery; D001787:Blood Group Incompatibility; D005260:Female; D005705:Gallbladder Diseases / Q000453:epidemiology*; D006801:Humans; D007583:Jejunum / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome