Acromegaly secondary to an incidentally discovered growth-hormone-releasing hormone secreting bronchial carcinoid tumour associated to a pituitary incidentaloma.
In this report we emphasize the opportunity of considering the uncommon causes of chronic GH-excess in the initial diagnostic process, such as GHRH hypersecretion, especially in the presence of ambiguous pituitary neuroimaging. This topic may have an important clinical significance in order to plan the most cost-effective diagnostic procedures and management and to avoid unnecessary pituitary neurosurgery.
Verrua
E
E
Unit of Endocrinology, Department of Medical Sciences, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Via F. Sforza 35, 20122, Milan, Italy.
Ronchi
C L
CL
Ferrante
E
E
Ferrari
D I
DI
Bergamaschi
S
S
Ferrero
S
S
Zatelli
M C
MC
Branca
V
V
Spada
A
A
Beck-Peccoz
P
P
Lania
A G
AG
D000172:Acromegaly / Q000175:diagnosis*; D001984:Bronchial Neoplasms / Q000175:diagnosis*; D002276:Carcinoid Tumor / Q000175:diagnosis*; D005260:Female; D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis*
D013007:Growth Hormone-Releasing Hormone