title: Chemical composition and antimicrobial activity of the essential oil from Ferula glauca L. (F. communis L. subsp. glauca) growing in Marche (central Italy).
abstract: The essential oil obtained from different parts of Ferula glauca L. (formerly considered as a subspecies of F. communis) growing in Marche (central Italy), was analyzed for the first time by GC-FID and GC-MS. The major volatiles were (E)-caryophyllene and caryophyllene oxide in leaves, alpha-pinene, myrcene and germacrene D in flowers, alpha- and beta-pinene in fruits, (E)-beta-farnesene, myristicin and elemicin in roots, respectively. The differences in composition detected with respect to F. communis, made the volatile fraction a reliable marker to distinguish between them, and confirm the botanical data at the base of their discrimination. Furthermore, the oil was assayed for its antimicrobial activity by the broth microdilution method. B. subtilis was found to be the most sensitive microorganism, with the lowest MIC values.
authors.affiliation: Department of Environmental Sciences, Section of Botany and Ecology, University of Camerino, Via Pontoni 5, I-62032 Camerino, Italy. filippo.maggi@unicam.it
authors.forename: Filippo
authors.initials: F
authors.lastname: Maggi
authors.forename: Cinzia
authors.initials: C
authors.lastname: Cecchini
authors.forename: Alberto
authors.initials: A
authors.lastname: Cresci
authors.forename: Maria M
authors.initials: MM
authors.lastname: Coman
authors.forename: Bruno
authors.initials: B
authors.lastname: Tirillini
authors.forename: Gianni
authors.initials: G
authors.lastname: Sagratini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Papa
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects; D005309:Ferula / Q000737:chemistry*; D007558:Italy; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D013729:Terpenes