title: Cell surface enzyme attachment is mediated by family 37 carbohydrate-binding modules, unique to Ruminococcus albus.
abstract: The rumen bacterium Ruminococcus albus binds to and degrades crystalline cellulosic substrates via a unique cellulose degradation system. A unique family of carbohydrate-binding modules (CBM37), located at the C terminus of different glycoside hydrolases, appears to be responsible both for anchoring these enzymes to the bacterial cell surface and for substrate binding.
authors.affiliation: Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel.
authors.forename: Anat
authors.initials: A
authors.lastname: Ezer
authors.forename: Erez
authors.initials: E
authors.lastname: Matalon
authors.forename: Sadanari
authors.initials: S
authors.lastname: Jindou
authors.forename: Ilya
authors.initials: I
authors.lastname: Borovok
authors.forename: Nof
authors.initials: N
authors.lastname: Atamna
authors.forename: Zhongtang
authors.initials: Z
authors.lastname: Yu
authors.forename: Mark
authors.initials: M
authors.lastname: Morrison
authors.forename: Edward A
authors.initials: EA
authors.lastname: Bayer
authors.forename: Raphael
authors.initials: R
authors.lastname: Lamed
mesh_terms: D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism*; D001665:Binding Sites; D002482:Cellulose / Q000378:metabolism*; D003001:Cloning, Molecular; D006026:Glycoside Hydrolases / Q000378:metabolism*; D009154:Mutation; D011485:Protein Binding; D045857:Ruminococcus / Q000201:enzymology*; D013379:Substrate Specificity
chemical_list: D001426:Bacterial Proteins; D002482:Cellulose; D006026:Glycoside Hydrolases