Detection of clinically significant QTc prolongation in phase I studies in healthy participants: comparison of 2 semiautomated QT measurement methods.
Sarapa
Nenad
N
Daiichi Sankyo Pharma Development, Edison, New Jersey, USA. nsarapa@its.jnj.com
Francom
Steven F
SF
Azzam
Sara M
SM
Wickremasingha
Prachi K
PK
Tyl
Benoit
B
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004311:Double-Blind Method; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011759:Pyrrolidines / Q000009:adverse effects*; D015363:Quinolones / Q000009:adverse effects*; D055815:Young Adult
D000900:Anti-Bacterial Agents; C505440:DX 619; D011759:Pyrrolidines; D015363:Quinolones