title: Review of 67 patients with autoimmune pancreatitis in Korea: a multicenter nationwide study.
abstract: OBJECTIVE
  The ideal diagnostic criteria of autoimmune pancreatitis (AIP) are still challenging. Therefore, we investigated the clinical features of AIP in Korea and assessed the clinical use of new Korean diagnostic criteria.
  
  
  METHODS
  We reviewed 67 patients with AIP enrolled in 16 hospitals via a multicenter study. The diagnosis was confirmed according to the Korean diagnostic criteria that included pancreatic imaging, laboratory findings, histopathology, and response to steroid.
  
  
  RESULTS
  Mean age of the patients was 56 years, and 73% were men. Obstructive jaundice (52%) was the most common symptom, and 14 patients (21%) had other organ involvement. Fifty-four patients (81%) revealed diffuse swelling of the pancreas. Either immunoglobulin (Ig)G or IgG4 was elevated in 76%. According to the Korean criteria, 65 patients had definite diagnostic criteria, and 2 patients had probable criteria. Fifteen patients were fulfilled with image, serological, and histopathologic criteria, and 4 patients could be diagnosed with image and steroid responsiveness. Ten patients experienced recurrent attacks of AIP during the mean 20-month follow-up.
  
  
  CONCLUSIONS
  Among 67 cases of AIP, either IgG or IgG4 was elevated in 76% of patients, and 14 patients (21%) had other organ involvement. New Korean diagnostic criteria are useful for diagnosis of AIP.
authors.affiliation: Autoimmune Pancreatitis Study Group, Korean Society of Pancreatobiliary Diseases, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Ji Kon
authors.initials: JK
authors.lastname: Ryu
authors.forename: Jae Bock
authors.initials: JB
authors.lastname: Chung
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Park
authors.forename: Jong Kyun
authors.initials: JK
authors.lastname: Lee
authors.forename: Kyu Tack
authors.initials: KT
authors.lastname: Lee
authors.forename: Woo Jin
authors.initials: WJ
authors.lastname: Lee
authors.forename: Jong Ho
authors.initials: JH
authors.lastname: Moon
authors.forename: Kwang Bum
authors.initials: KB
authors.lastname: Cho
authors.forename: Dae Whan
authors.initials: DW
authors.lastname: Kang
authors.forename: Jin-Hyeok
authors.initials: JH
authors.lastname: Hwang
authors.forename: Kyo-Sang
authors.initials: KS
authors.lastname: Yoo
authors.forename: Byung Moo
authors.initials: BM
authors.lastname: Yoo
authors.forename: Don Hang
authors.initials: DH
authors.lastname: Lee
authors.forename: Hae Kyung
authors.initials: HK
authors.lastname: Kim
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Moon
authors.forename: Jin
authors.initials: J
authors.lastname: Lee
authors.forename: Hong Sik
authors.initials: HS
authors.lastname: Lee
authors.forename: Ho Sun
authors.initials: HS
authors.lastname: Choi
authors.forename: Sung Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Yong-Tae
authors.initials: YT
authors.lastname: Kim
authors.forename: Chang Duck
authors.initials: CD
authors.lastname: Kim
authors.forename: Sun Joo
authors.initials: SJ
authors.lastname: Kim
authors.forename: Joon Soo
authors.initials: JS
authors.lastname: Hahm
authors.forename: Yong Bum
authors.initials: YB
authors.lastname: Yoon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003951:Diagnostic Errors / Q000517:prevention & control; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007723:Korea; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D011237:Predictive Value of Tests; D012008:Recurrence; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015854:Up-Regulation; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G; D013256:Steroids