Quick two-dimensional differential in gel electrophoresis-based method to determine length and secondary structures of telomeric DNA.
A novel differential in gel electrophoresis (DIGE)-based method has been developed and applied to measure telomere length and appearance of two-dimensional structural DNA changes. It can be applied to any area requiring quick and evident measurement of structural DNA changes.
Lyakhovich
Alex
A
Department of Genetics and Microbiology, Universitad Autonoma de Barcelona, Edifici C UAB Campus, Bellaterra 08193, Spain. alex.lyakhovich@uab.es
Bech-Serra
Joan J
JJ
Canals
Francesc
F
Surralles
Jordi
J
D004247:DNA / Q000737:chemistry*; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D009690:Nucleic Acid Conformation; D013329:Structure-Activity Relationship; D016615:Telomere / Q000737:chemistry*
D004247:DNA