Ultrasonic strain versus coronary flow velocity pattern for predicting regional wall motion recovery after primary coronary intervention for acute myocardial infarction.
BACKGROUND
Strain Doppler echocardiography can detect regional myocardial dysfunction after acute myocardial infarction (AMI). The aim of this study was to assess the utility of strain in predicting regional wall motion recovery after AMI compared with the coronary flow velocity pattern.


METHODS
Thirty-three patients with anterior AMIs undergoing successful coronary intervention were included. Longitudinal myocardial strain and coronary flow velocity were measured <24 hours after coronary intervention. Regional wall motion was analyzed by the anterior wall motion score index (A-WMSI).


RESULTS
End-systolic strain (r = 0.72, P < .0001), peak strain (r = 0.58, P < .005), and corrected time to peak strain (the time delay from end-systolic to peak strain divided by the RR interval) (r = 0.80, P < .0001) showed good correlations with A-WMSI at 4 weeks. Similarly, diastolic deceleration time was significantly correlated with A-WMSI at 4 weeks (r = 0.69, P < .0001). The diagnostic value in predicting wall motion recovery was compared using a receiver operating characteristic curve. The area under the curve of corrected time to peak strain tended to be larger than that of diastolic deceleration time (0.94 +/- 0.04 vs 0.86 +/- 0.06).


CONCLUSIONS
Strain can predict left ventricular wall motion recovery in patients with AMIs after coronary intervention comparable with predictions using the coronary flow velocity pattern.
Ohara
Yoshikazu
Y
Division of Cardiology, Kochi Health Sciences Center, Kochi, Japan. yosikazu_ohara@khsc.or.jp
Furuno
Takashi
T
Takahashi
Takefumi
T
Hosokawa
Shinobu
S
Hiasa
Yoshikazu
Y
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation; D004452:Echocardiography / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000601:surgery*; D011379:Prognosis; D020127:Recovery of Function; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000601:surgery*