A rare case of follicular thyroid carcinoma in ovarian struma.
Struma ovarii is a form of specialised mature teratoma, with predominantly mature thyroid tissue in an ovarian teratoma as seen in 2% of cases. Its malignant transformation is even rarer and is seen in only 5% of those cases. This 40-year-old female patient had an incidental finding of a pelvic mass during investigation of secondary amenorrhoea. She underwent a staging laparotomy and pelvic clearance. The histopathology revealed a bilateral mature teratoma of the ovary with follicular thyroid carcinoma in the right ovarian struma (malignant struma). A total thyroidectomy was performed followed by a whole body 31I scintigraphy which did not reveal any abnormal uptake of isotope. The patient remains well after four years and is being followed-up with serial serum thyroglobulin surveillance.
Prasad
P
P
Department of Gynaecology, Nottingham University Hospitals NHS Trust, City Hospital Campus, Hucknall Road, Nottingham NG5 1PB, UK. praminik@btinternet.com
Nunns
D
D
Ubhi
C S
CS
Chaudry
Z
Z
Soomro
I
I
D018263:Adenocarcinoma, Follicular / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013330:Struma Ovarii / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy; D014463:Ultrasonography