Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-alkanethiol co-adsorbed monolayer.
Densely packed co-adsorbed ultrathin mono molecular layers of short tri(ethylene glycol)-alkanethiolate (for repelling proteins) and maltoside terminated alkanethiolate (for capturing lectin) provided an extremely high signal to noise ratio surface: the repelling molecules, which had two different functions (highly flexible-hydrophilic arm and rigid packing tail group), worked as "nano barriers" in the recognition monolayer.
Sato
Yukari
Y
National Institute of Advanced Industrial Science and Technology, Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan. yukari-sato@aist.go.jp
Yoshioka
Kyoko
K
Tanaka
Mutsuo
M
Murakami
Teiichi
T
Ishida
Miho Neide
MN
Niwa
Osamu
O
D000327:Adsorption; D000473:Alkanes / Q000737:chemistry*; D000818:Animals; D002417:Cattle; D003208:Concanavalin A / Q000032:analysis* / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D000473:Alkanes; D010455:Peptides; D013438:Sulfhydryl Compounds; D003208:Concanavalin A; C028914:triethylene glycol; D011092:Polyethylene Glycols