title: Experience with Endeavor stent implantations.
abstract: Restenosis is the most common disadvantage of percutaneous coronary interventions. The incidence of restenosis can be lowered with the use of stents. After the use of stents, 'in-stent' restenosis can occur. To avoid it drug-eluting stents were developed, but the occurrence of stent thrombosis is higher than observed in case of bare-metal stents. Endeavor is a new zotarolimus-eluting stent developed to reduce the stent thrombosis.
  
  
  OBJECTIVE
  In a prospective study we aimed to follow-up our patients regarding the incidence of in-stent restenosis, stent thrombosis, and clinical end points after Endeavor stent implantation.
  
  
  METHODS
  Endeavor stents have been implanted in patients undergoing coronary angiography with the following indications: complex lesions susceptible to restenosis and after recanalization of chronic total occlusions.
  
  
  RESULTS
  Endeavor stent implantations were successfully performed in 99 patients and has been successful in 98% of cases, two stents could not be implanted because of technical difficulties. Significant restenosis was observed in eight patients (8.1%). Subacute stent thrombosis (within 10 days) occurred in two patients (2.0%). Any late stent thrombosis was not observed.
  
  
  CONCLUSIONS
  Our registry affirmed the results of the Endeavor I trial in a population with more severe and longer coronary stenosis. We can conclude that the Endeavor stent is suitable for implantation in complex, longer coronary lesions. Our long-term follow-up data do not prove those opinions which prefer bare-metal stent implantation in all patients because of the late adverse events of the drug-eluting stents.
authors.affiliation: Department of Cardiology, Zala County Hospital, Zalaegerszeg, Hungary.
authors.forename: Géza
authors.initials: G
authors.lastname: Lupkovics
authors.forename: András
authors.initials: A
authors.lastname: Kenéz
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Németh
authors.forename: Akos
authors.initials: A
authors.lastname: Motyovszki
authors.forename: István
authors.initials: I
authors.lastname: Takács
authors.forename: Elõd
authors.initials: E
authors.lastname: Papp
mesh_terms: D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome