title: Effects of lotioned disposable handkerchiefs on skin barrier recovery after tape stripping.
abstract: OBJECTIVE
  In the present work, it was studied whether repeated use of lotioned disposable handkerchiefs on tape-stripped forearm skin was able to improve skin barrier recovery.
  
  
  METHODS
  Skin assessments included scoring of visual erythema and dryness/scaliness; and measuring of skin redness (Chromameter CR300), skin hydration (Corneometer CM825), and transepidermal water loss (Tewameter TM300). Four different lotioned paper handkerchiefs - randomly assigned to one of two subject groups (n=20) - were tested vs. the non-lotioned control handkerchief. The results were also compared with those obtained using a topically applied oil-in-water barrier cream (Dermalex).
  
  
  RESULTS
  The three-day lasting protocol revealed that handkerchief wiping itself delayed skin recovery, but a significantly better performance was seen for the lotioned handkerchiefs containing fatty alcohols and mineral oils. This shows that the use of lotioned tissues helps to prevent skin damage inevitably caused by the wiping process.
  
  
  CONCLUSIONS
  The controlled pre-damaged forearm method with tape stripping appears to be a suitable model to study the effects of repetitive wiping on irritated skin with disposable handkerchiefs of different quality. More specifically, the model seems applicable to mimic the nasolabial skin damage observed during a common cold associated with frequent use of disposable handkerchiefs.
authors.affiliation: Department of Toxicology, Dermato-Cosmetology and Pharmacognosy, Vrije Universiteit Brussel, Brussels, Belgium. kdepaepe@vub.ac.be
authors.forename: Kristien
authors.initials: K
authors.lastname: De Paepe
authors.forename: Evelien
authors.initials: E
authors.lastname: De Rop
authors.forename: Evi
authors.initials: E
authors.lastname: Houben
authors.forename: Ralf
authors.initials: R
authors.lastname: Adam
authors.forename: Vera
authors.initials: V
authors.lastname: Rogiers
mesh_terms: D000293:Adolescent; D000328:Adult; D001458:Bandages; D004209:Disposable Equipment; D005260:Female; D006801:Humans; D009824:Ointments / Q000008:administration & dosage*; D012867:Skin / Q000293:injuries*; D053832:Surgical Tape / Q000009:adverse effects*; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000628:therapy*; D055815:Young Adult
chemical_list: D009824:Ointments