Prognostic significance of myocardial ischemia by dobutamine stress echocardiography in patients without angina pectoris after coronary revascularization.
The clinical utility of stress testing in patients without angina pectoris after revascularization has been questioned. Dobutamine stress echocardiography (DSE) is an established technique for detection of myocardial ischemia and cardiac risk stratification. We studied the prognostic value of DSE in 393 patients without typical angina pectoris after coronary revascularization. Ischemia was incremental to clinical data in predicting all-cause death (hazard ratio 3.5, 95% confidence interval 1.8 to 6.7) and cardiac death (hazard ratio 4.2, 95% confidence interval 1.8 to 9.8). In conclusion, myocardial ischemia during DSE is independently associated with an increased risk of all-cause mortality and cardiac death in these patients after adjustment for clinical data.
Pedone
Chiara
C
Department of Cardiology, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Elhendy
Abdou
A
Biagini
Elena
E
van Domburg
Ron T
RT
Schinkel
Arend F
AF
Di Pasquale
Giuseppe
G
Bax
Jeroen J
JJ
Poldermans
Don
D
D000368:Aged; D000787:Angina Pectoris; D003324:Coronary Artery Disease / Q000628:therapy*; D003643:Death; D025401:Echocardiography, Stress; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000401:mortality* / Q000601:surgery; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment