title: Identifying biological markers of activity in human nociceptive pathways to facilitate analgesic drug development.
authors.affiliation: GlaxoSmithKline, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2GG, UK Department of Neural and Pain Sciences, Dental School and Program in Neuroscience, University of Maryland, Baltimore, MD 21201, USA University of Michigan and VA Medical Center, Ann Arbor, MI 48109, USA Pain Research Center, Anesthesia Department, Stanford University, Stanford, CA 94305 and LASMED LLC, Mountain View, CA 94043, USA Department of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM), University of Heidelberg, D-68167 Mannheim, Germany.
authors.forename: Boris A
authors.initials: BA
authors.lastname: Chizh
authors.forename: Joel D
authors.initials: JD
authors.lastname: Greenspan
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Casey
authors.forename: Michael I
authors.initials: MI
authors.lastname: Nemenov
authors.forename: Rolf-Detlef
authors.initials: RD
authors.lastname: Treede
mesh_terms: D000344:Afferent Pathways / Q000187:drug effects* / Q000378:metabolism*; D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D003198:Computer Simulation; D015195:Drug Design; D006801:Humans; D008954:Models, Biological; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism
chemical_list: D000700:Analgesics; D015415:Biomarkers