Alteration of CXCR4 expression and Th1/Th2 balance of peripheral CD4-positive T cells can be a biomarker for leukocytapheresis therapy for patients with refractory ulcerative colitis.
Nakase
Hiroshi
H
Mikami
Sakae
S
Chiba
Tsutomu
T
D000328:Adult; D015415:Biomarkers / Q000378:metabolism*; D003093:Colitis, Ulcerative / Q000276:immunology* / Q000628:therapy*; D005260:Female; D006801:Humans; D007937:Leukapheresis; D008297:Male; D008875:Middle Aged; D019718:Receptors, CXCR4 / Q000276:immunology / Q000378:metabolism*; D018417:Th1 Cells / Q000276:immunology / Q000378:metabolism; D018418:Th2 Cells / Q000276:immunology / Q000378:metabolism
D015415:Biomarkers; C527276:CXCR4 protein, human; D019718:Receptors, CXCR4