New biomedical strategies for HIV-1 prevention in women.
Novel HIV-1 prevention strategies continue to be urgently needed. This article reviews the current state of biomedical prevention against HIV-1, focusing on recently completed and ongoing clinical trials of new prevention interventions, particularly those relevant to prevention of HIV-1 in women. Male circumcision, cervical barrier devices, suppressive therapy against herpes simplex virus type 2, treatment of vaginal infections and other vaginal health interventions, pre-exposure antiretroviral prophylaxis, and topical vaginal microbicides are discussed.
Baeten
Jared M
JM
Departments of Global Health and Medicine, University of Washington, 901 Boren Avenue, Suite 1300, Seattle, WA 98104, USA. jbaeten@u.washington.edu