title: Fluorescence and biological evaluation of the La(III) and Eu(III) complexes with 7-methoxychromone-3-carbaldehyde benzoyl hydrazone Schiff base.
abstract: A novel Schiff base ligand (L = 7-methoxychromone-3-carbaldehyde benzoyl hydrazone) and its La(III) and Eu(III) complexes have been successfully prepared. The crystal structure of [LaL(2)(NO(3))(3)].H(2)O was characterized by X-ray crystallography. It crystallizes in monoclinic, space group C2/c with crystallographic data: a = 27.7173(17) A, b = 10.0002(6) A, c = 14.7884(9) A, beta = 102.6870(10) degrees and Z = 4. In the structure, the La(III) ion satisfies 12 coordination and three nitrate coordinate as bidentate ligand. The biological experiments show that the ligand and its two complexes can strongly bind to DNA through intercalation mode, and the three compounds also exhibit good antioxidant activities against OH(*) and O(2) (-*). Moreover, it is found that the Eu(III) complex exhibits characteristic fluorescence of europium ion in different organic solvent.
authors.affiliation: College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Dong-dong
authors.initials: DD
authors.lastname: Qin
authors.forename: Gao-fei
authors.initials: GF
authors.lastname: Qi
authors.forename: Zheng-yin
authors.initials: ZY
authors.lastname: Yang
authors.forename: Jin-cai
authors.initials: JC
authors.lastname: Wu
authors.forename: Yong-chun
authors.initials: YC
authors.lastname: Liu
mesh_terms: D000042:Absorption; D000970:Antineoplastic Agents / Q000032:analysis; D002867:Chromones / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004247:DNA / Q000032:analysis / Q000378:metabolism*; D005063:Europium / Q000737:chemistry*; D005453:Fluorescence; D016166:Free Radical Scavengers / Q000737:chemistry / Q000378:metabolism; D006835:Hydrazones / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry; D007364:Intercalating Agents / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry* / Q000378:metabolism*; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared; D013481:Superoxides / Q000737:chemistry; D014783:Viscosity
chemical_list: C539586:7-methoxychromone-3-carbaldehyde-benzoylhydrazone; D000970:Antineoplastic Agents; D002867:Chromones; D016166:Free Radical Scavengers; D006835:Hydrazones; D007364:Intercalating Agents; D008024:Ligands; D009942:Organometallic Compounds; D012997:Solvents; D013481:Superoxides; D017665:Hydroxyl Radical; D005063:Europium; D007811:Lanthanum; D004247:DNA