title: Dimensional structure of the autism phenotype: relations between early development and current presentation.
abstract: The dimensional structure of higher functioning autism phenotype was investigated by factor analysis. The goal of this study was to identify the degree to which early symptoms of autism (measured using the ADI-R) could be predictive of the current symptoms of autism as identified using the ADOS, the adaptive behavior scales, IQ scores and theory of mind scores. Participants included 140 subjects with Full Scale IQ > 70 (104 with autism spectrum diagnosis, 36 with non autism diagnosis, age range 6-24). For the early development as well as for the current presentation a multi-factor solution was found. In line with other studies we found that the social interaction and communication domains are closely related to one factor namely: Social communication. An additional factor implies anxious and compulsive behavior which is associated with current social communication functioning.
authors.affiliation: Department of Child and Adolescent Psychiatry, Philipps-University Marburg, Marburg, Germany. kampbeck@med.uni-marburg.de
authors.forename: Inge
authors.initials: I
authors.lastname: Kamp-Becker
authors.forename: Mardjan
authors.initials: M
authors.lastname: Ghahreman
authors.forename: Judith
authors.initials: J
authors.lastname: Smidt
authors.forename: Helmut
authors.initials: H
authors.lastname: Remschmidt
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D001007:Anxiety / Q000523:psychology; D001321:Autistic Disorder / Q000175:diagnosis / Q000523:psychology*; D002648:Child; D002657:Child Development; D003142:Communication; D003192:Compulsive Behavior / Q000523:psychology*; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007360:Intelligence; D007398:Interpersonal Relations; D016014:Linear Models; D008297:Male; D009483:Neuropsychological Tests; D010641:Phenotype; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012919:Social Behavior; D013239:Stereotyped Behavior; D055815:Young Adult