title: Trypanosoma cruzi: a stage-specific calpain-like protein is induced after various kinds of stress.
abstract: Calpains are calcium-dependent cysteine proteinases found in all living organisms and are involved in diverse cellular processes. Calpain-like proteins have been reported after in silico analysis of the Tritryps genome and are believed to play important roles in cell functions of trypanosomatids. We describe the characterization of a member of this family, which is differentially expressed during the life-cycle of Trypanosoma cruzi.
authors.affiliation: Instituto Carlos Chagas-Fiocruz, Curitiba, PR, Brasil.
authors.forename: Viviane
authors.initials: V
authors.lastname: Giese
authors.forename: Bruno
authors.initials: B
authors.lastname: Dallagiovanna
authors.forename: Fabricio K
authors.initials: FK
authors.lastname: Marchini
authors.forename: Daniela P
authors.initials: DP
authors.lastname: Pavoni
authors.forename: Marco A
authors.initials: MA
authors.lastname: Krieger
authors.forename: Samuel
authors.initials: S
authors.lastname: Goldenberg
mesh_terms: D000818:Animals; D015153:Blotting, Western; D002154:Calpain / Q000096:biosynthesis* / Q000235:genetics; D008018:Life Cycle Stages / Q000235:genetics* / Q000502:physiology; D016133:Polymerase Chain Reaction; D015800:Protozoan Proteins / Q000096:biosynthesis* / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014349:Trypanosoma cruzi / Q000235:genetics / Q000254:growth & development*
chemical_list: D015800:Protozoan Proteins; D012333:RNA, Messenger; C540143:CALPx11 protein, Trypanosoma cruzi; D002154:Calpain