title: Clinical epidemiological profile of American tegumentary leishmaniasis at the Pinto Sugar Mill in Moreno Municipality, Greater Metropolitan Recife, Pernambuco State, Brazil.
abstract: American tegumentary leishmaniasis (ATL) is present in all regions of Pernambuco State, Brazil, where it is spreading, with the emergence of foci in new areas like the Municipality (County) of Moreno in Greater Metropolitan Recife. The objective of the current study was to assess the prevalence of infection and identify autochthonous cases of ATL. In April 2006 a population survey was performed using a questionnaire and the Montenegro skin test (MST) in 481 individuals from the Pinto Sugar Mill, of whom 47% were males and 74% were younger than 30 years. One hundred forty-four individuals (30%) showed a positive MST. Of these, five presented active lesions, 41 were cured after meglumine antimoniate treatment, and one showed a spontaneous cure. Indirect immunofluorescence (IIF) was performed on sera from 89 individuals and showed a 36% positive rate. The high ATL prevalence demonstrates the epidemiological spread of the disease in Greater Metropolitan Recife, a worrisome development since there are no effective measures for ATL control except ecological awareness raising to minimize the risk of infection.
authors.affiliation: Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Recife, Brasil.
authors.forename: Maria Edileuza Felinto de
authors.initials: ME
authors.lastname: Brito
authors.forename: Cláudio Júlio
authors.initials: CJ
authors.lastname: Silva
authors.forename: Cristiane Máximo
authors.initials: CM
authors.lastname: Silva
authors.forename: Pedro Raposo
authors.initials: PR
authors.lastname: Salazar
authors.forename: Juliana Santos
authors.initials: JS
authors.lastname: Coutinho
authors.forename: Luiza de Campos
authors.initials: Lde C
authors.lastname: Reis
authors.forename: Valéria Rego Alves
authors.initials: VR
authors.lastname: Pereira
authors.forename: Sinval Pinto
authors.initials: SP
authors.lastname: Brandão-Filho
authors.forename: Angela Cristina Rapela
authors.initials: AC
authors.lastname: Medeiros
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology* / Q000635:transmission; D008297:Male; D008875:Middle Aged; D012424:Rural Population; D011795:Surveys and Questionnaires; D055815:Young Adult