[Atypical pulmonary carcinoid tumor with abnormal elevation of serum gastrin-releasing peptide precursor: report of a case].
We report a rare case of atypical pulmonary carcinoid tumor accompanied by elevation of serum gastrin-releasing peptide precursor (ProGRP). A 55-year-old male presented to our hospital with a history of bloody sputum. The level of serum ProGRP was elevated to 781 pg/ml (normal < 46 pg/ml). Chest computed tomography (CT) revealed a solitary pulmonary tumor in the left lower lobe with sub-carinal lymph node enlargement. Transbronchial lung biopsy showed a pulmonary carcinoid, therefore left lower lobectomy with mediastinal lymph node dissection was performed. ProGRP decreased to normal level 1 month after operation. Histopathological diagnosis showed an atypical pulmonary carcinoid tumor.
Endo
T
T
Department of Thoracic Surgery, Jichi Medical School, Shimotsuke, Japan.
Hasegawa
T
T
Tezuka
Y
Y
Kanai
Y
Y
Otani
S
S
Yamamoto
S
S
Tetsuka
K
K
Sato
Y
Y
Endo
S
S
Sohara
Y
Y
D014408:Biomarkers, Tumor / Q000097:blood*; D001706:Biopsy; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000097:blood*; D011013:Pneumonectomy; D011994:Recombinant Proteins / Q000097:blood; D016896:Treatment Outcome
D014408:Biomarkers, Tumor; D010446:Peptide Fragments; D011994:Recombinant Proteins; C087079:pro-gastrin-releasing peptide (31-98)