Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root.
During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation.
De Smet
Ive
I
Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), B-9052 Ghent, Belgium.
Vassileva
Valya
V
De Rybel
Bert
B
Levesque
Mitchell P
MP
Grunewald
Wim
W
Van Damme
Daniël
D
Van Noorden
Giel
G
Naudts
Mirande
M
Van Isterdael
Gert
G
De Clercq
Rebecca
R
Wang
Jean Y
JY
Meuli
Nicholas
N
Vanneste
Steffen
S
Friml
Jirí
J
Hilson
Pierre
P
Jürgens
Gerd
G
Ingram
Gwyneth C
GC
Inzé
Dirk
D
Benfey
Philip N
PN
Beeckman
Tom
T
D017360:Arabidopsis / Q000166:cytology* / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism*; D002455:Cell Division; D019070:Cell Lineage; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D018519:Meristem / Q000166:cytology* / Q000201:enzymology / Q000254:growth & development; D009154:Mutation; D018517:Plant Roots / Q000166:cytology* / Q000201:enzymology / Q000254:growth & development; D017346:Protein Serine-Threonine Kinases; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000378:metabolism*
D029681:Arabidopsis Proteins; D011956:Receptors, Cell Surface; C462019:ACR4 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases