title: The ketogenic diet in children with Glut1 deficiency syndrome and epilepsy.
abstract: The effects of a long-term ketogenic diet in children with Glut1 deficiency syndrome on metabolism are unknown. Our results indicate a characteristic effect of a long-term ketogenic diet on glucose and lipid homeostasis in Glut1 deficiency syndrome. Although serum lipids and apolipoproteins reflect a proatherogenic lipoprotein profile, adipocytokine constellation is not indicative of enhanced cardiovascular risk.
authors.affiliation: Department of Pediatrics IV, Division of Neuropediatrics, University Hospital Innsbruck, Innsbruck, Austria. markus_rauchenzauner@hotmail.com
authors.forename: Markus
authors.initials: M
authors.lastname: Rauchenzauner
authors.forename: Jörg
authors.initials: J
authors.lastname: Klepper
authors.forename: Bärbel
authors.initials: B
authors.lastname: Leiendecker
authors.forename: Gerhard
authors.initials: G
authors.lastname: Luef
authors.forename: Kevin
authors.initials: K
authors.lastname: Rostasy
authors.forename: Christoph
authors.initials: C
authors.lastname: Ebenbichler
mesh_terms: D054392:Adipokines / Q000378:metabolism; D001053:Apolipoproteins / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000150:complications* / Q000178:diet therapy*; D005260:Female; D005947:Glucose / Q000378:metabolism; D051272:Glucose Transporter Type 1 / Q000172:deficiency*; D006706:Homeostasis; D006801:Humans; D007333:Insulin Resistance; D007657:Ketone Bodies / Q000378:metabolism*; D008055:Lipids / Q000737:chemistry; D008297:Male; D054411:Receptors, Leptin / Q000378:metabolism
chemical_list: D054392:Adipokines; D001053:Apolipoproteins; D051272:Glucose Transporter Type 1; D007657:Ketone Bodies; D008055:Lipids; D054411:Receptors, Leptin; C495677:SLC2A1 protein, human; D005947:Glucose