Aryl-aryl crosss-couplings that avoid the preparation of haloaromatics.
Advances in the development of cross-coupling protocols that avoid haloaromatics are reviewed. Most of the reports that are discussed appeared in the literature within the past 2 years and describe either alternatives to halogenated electrophiles or halogen-free preparations of the organometallic partners. However, while this review is not limited to cross-couplings that are entirely free of haloaromatics, coverage of the topic is largely restricted to reactions affording new aryl-aryl, aryl-heteroaryl and heteroaryl-heteroaryl carbon-carbon bonds during the cross-coupling event.
Norberg
A Monica
AM
Michigan State University, Department of Chemistry, 540 Chemistry, East Lansing, MI 48824, USA.
Sanchez
Luis
L
Maleczka
Robert E
RE
D002384:Catalysis; D002626:Chemistry, Pharmaceutical; D055808:Drug Discovery; D006219:Halogens / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*
D006219:Halogens; D004364:Pharmaceutical Preparations