[Rat immunoreactivity in experimental modeling of acute autohemorrhagic bihemispheric stroke in the presence of staphylococcal infection].
Experimental studies were made of rat immunoreactivity in experimental modeling of acute hemorrhagic stroke in staphylococcal infection. Bactericidal activity and reserve bactericidal activity of neutrophils in NBT-test enhance while mid-molecular CIC level decreases because of phagocyte activation. ABA high titers in blood reflect activation of autoimmune processes. Splenic mass increased suggesting activation of proliferation of splenic lymphoid cells or enhanced migration of immature lymphoid cells from bone marrow to the spleen. Experimental animals had suppressed functional activity of main lymphoid cells populations in blast-transformation reaction which may affect the course of early recovery, promote activation of infectious bacterial process, autoaggression. The results of the studies can serve the basis for further investigations of immune mechanisms involved in development of hemorrhagic stroke in the presence of infectious process.
Makarenko
A N
AN
Mironiuk
Iu N
IuN
Molozhavaia
O S
OS
Pozur
V K
VK
Iablonskaia
S V
SV
D000818:Animals; D001854:Bone Marrow Cells / Q000276:immunology; D049109:Cell Proliferation; D008213:Lymphocyte Activation / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D051381:Rats; D013154:Spleen / Q000276:immunology; D013203:Staphylococcal Infections / Q000276:immunology*; D020521:Stroke / Q000276:immunology* / Q000382:microbiology