title: Effect of curing characteristics on residual stress generation in polymethyl methacrylate bone cements.
abstract: Residual stresses resulting from the shrinkage of polymethyl methacrylate (PMMA) bone cement have been implicated in the formation of cracks in cement mantles following total hip arthroplasty. This study investigates whether two such cements, with differentiated solidification characteristics (i.e. working and setting times), display significant differences in their residual stress characteristics in an experiment designed to replicate the physical conditions of total hip arthroplasty. Experiments were performed using a representative femoral construct to measure and compare the temperatures and residual strains developed for standard PMMA cement mantles (CMW 1 Gentamicin) and slow curing cement mantles (SmartSet HV Gentamicin) during and following polymerization. These experimental results revealed no statistically significant difference (t-test, p > 0.05) for peak exotherm temperature and residual strain levels between the cements (measured after 3 h). The tailored polymerization characteristics of the slow-curing cement do not significantly affect residual stress generation, compared with the standard cement. It is often considered that residual stresses significantly relax following polymerization and before biomechanical loads are first applied during rehabilitation (up to 3 days later). This was examined for durations of 18 h to 3 days. Axial strains in the model femur and stem reduced by averages of 5.5 and 7.9 per cent respectively, while hoop strains in the stem exhibited larger reductions. An axisymmetric transient thermoelastic finite element model of the experiment was developed, allowing residual stresses to be predicted based on differential scanning calorimetry (DSC) measurements of the heat released throughout the exothermic curing reaction. The model predictions closely replicated the experimental measurements of both temperature and residual strain at 3 h, suggesting that residual strains can be fully accounted for by the thermal contraction mechanism associated with cooling after solidification.
authors.affiliation: Materials Processing Research Centre, School of Mechanical and Manufacturing Engineering, Dublin City University, Dublin, Ireland.
authors.forename: J A
authors.initials: JA
authors.lastname: Hingston
authors.forename: N J
authors.initials: NJ
authors.lastname: Dunne
authors.forename: L
authors.initials: L
authors.lastname: Looney
authors.forename: G B
authors.initials: GB
authors.lastname: McGuinness
mesh_terms: D000268:Adhesiveness; D001843:Bone Cements / Q000737:chemistry*; D002484:Cementation / Q000379:methods*; D003198:Computer Simulation; D006244:Hardness; D006358:Hot Temperature; D008956:Models, Chemical; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D013314:Stress, Mechanical
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate