title: [Sclerosing angiomatoid nodular transformation of the spleen].
abstract: Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a complex vascular lesion recently described. We present a case of SANT occurring in a 49-year-old woman who was treated for choroid melanoma. The computed tomography abdominal scan revealed an asymptomatic mass in the spleen. Splenectomy was performed due to the risk of metastasis from the melanoma. The histopathologic examination revealed an angiomatoid lesion composed of three types of vessels recapitulating the normal composition of the red pulp of the spleen. In this report, we discuss the pathology of this lesion and the differential diagnosis of SANT with other lesions such as hemangiomas, hamartomas and inflammatory pseudotumors.
authors.affiliation: Département de pathologie, institut Curie, 26 rue d'Ulm, Paris cedex 05, France.
authors.forename: Olfa
authors.initials: O
authors.lastname: Chouchane Mlik
authors.forename: Ségolène
authors.initials: S
authors.lastname: Lardenois
authors.forename: Rémy
authors.initials: R
authors.lastname: Salmon
authors.forename: Vincent
authors.initials: V
authors.lastname: Servois
authors.forename: Xavier
authors.initials: X
authors.lastname: Sastre-Garau
mesh_terms: D002830:Choroid Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D012598:Sclerosis / Q000473:pathology; D013154:Spleen / Q000098:blood supply / Q000473:pathology*; D013156:Splenectomy; D013158:Splenic Diseases / Q000473:pathology* / Q000601:surgery; D013160:Splenic Neoplasms / Q000473:pathology* / Q000601:surgery