[Interest of allergology evaluation for the treatment of asthma and rhinosinusitis].
Clinical allergy is the consequence of an inflammatory immune-mediated hyperresponsiveness, induced by the contact with environmental substances, defined as allergens. The diagnosis of clinical allergy is based on the history of the symptoms appearing when the subject is exposed to the allergens, in association with the detection of allergen specific IgE antibodies. The detection of the specific IgE is mainly based on the skin tests and sometimes on the blood result (RAST). The detection of the causative allergen offers therapeutic options such as avoidance and desensitization (immunotherapy). The allergen desensitization is a validated treatment, considered effective in rhinitis and allergic asthma.
Michel
O
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Clinique d'Immuno-allergologie, C.H.U. Brugmann, Bruxelles. omichel@ulb.ac.be
D000818:Animals; D001249:Asthma / Q000276:immunology* / Q000628:therapy; D003888:Desensitization, Immunologic / Q000379:methods; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D011058:Pollen / Q000276:immunology; D012120:Respiration Disorders / Q000276:immunology / Q000628:therapy; D012220:Rhinitis / Q000276:immunology / Q000628:therapy; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy; D012852:Sinusitis / Q000276:immunology / Q000628:therapy; D012882:Skin Tests
D007073:Immunoglobulin E