A new hexaaza bicyclic cyclophane with dual binding sites.
A new C3-symmetric drum-shaped homoditopic haxaamino bicyclic cyclophane and its hexachloride and hexaiodide complexes have been synthesized and characterized and dual recognition of guests has been demonstrated. Single-crystal X-ray analysis illustrates that bicyclic cyclophane has a cavity and side pockets for acetone molecules. The hexaprotonated state of this bicycle shows encapsulation of an iodide inside its cavity, and in hexachloride complex, chloride is recognized as Cl(-)...H2O in each of the three side pockets which are in extensive hydrogen bonding interactions with the water and chlorides. (1)H NMR experiments have also been carried out on hexatosylated cyclophane with the halides to study solution state binding.
Arunachalam
M
M
Department of Inorganic Chemistry, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mullick Road, Kolkata 700032, India.
Ravikumar
I
I
Ghosh
Pradyut
P
D053961:Azabicyclo Compounds / Q000737:chemistry*; D001665:Binding Sites; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy
D053961:Azabicyclo Compounds