The endosteum region keeps human leukemic stem cells alive.
Lapidot
Tsvee
T
Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel. tsvee.lapidot@weizmann.ac.il
Goichberg
Polina
P
Lapid
Kfir
K
Avigdor
Abraham
A
Kollet
Orit
O
D051997:ADP-ribosyl Cyclase 1 / Q000378:metabolism; D000818:Animals; D018952:Antigens, CD34 / Q000378:metabolism; D001853:Bone Marrow / Q000187:drug effects / Q000276:immunology / Q000473:pathology*; D016026:Bone Marrow Transplantation; D049109:Cell Proliferation; D002470:Cell Survival; D019008:Drug Resistance, Neoplasm; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D023421:Models, Animal; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000276:immunology / Q000473:pathology*
D018952:Antigens, CD34; D051997:ADP-ribosyl Cyclase 1