title: The 'Kinderkrebs in der Umgebung von Kernkraftwerken' study: results put into perspective.
abstract: A German case-control study on leukaemia in children below 5 y of age near nuclear installations showed a trend of increasing risk with decreasing distance of place of residence from the sites. The radiation exposure from the sites is considered as being too low by a factor of at least 1000 to explain the observed effect, but little is known about radiation effects from pre- or postnatal exposures on the leukaemia risk for ages up to 4 y. Within the study, it was shown that the observed trend in risk decreases over time. That could be indicative of some agent being involved for which the prevalence is reduced over time. Previous ecological studies showed increased risks among the youngest age groups in the closest vicinity of the sites, but no elevated risks for children of all ages (0-14). This could implicate a shift towards an earlier onset of the disease.
authors.affiliation: Federal Office for Radiation Protection, Ingolstaedter Landstr. 1, 85764 Oberschleissheim, Germany. bgrosche@bfs.de
authors.forename: Bernd
authors.initials: B
authors.lastname: Grosche
mesh_terms: D001822:Body Burden; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D016021:Epidemiologic Studies; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007953:Leukemia, Radiation-Induced / Q000453:epidemiology*; D055848:Nuclear Power Plants / Q000706:statistics & numerical data*; D011834:Radiation Monitoring / Q000706:statistics & numerical data; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors