title: Detection and management of pre-existing cognitive impairment and associated behavioral symptoms in the Intensive Care Unit.
abstract: Recent increase in both the elderly population and associated incidence of dementia are of critical importance to patient care in ICUs in the United States. Identification of pre-existing cognitive impairment, such as mild cognitive impairment and dementia, could prevent delirium and associated morbidity and mortality in the ICU. Additionally, noncognitive behavioral symptoms, such as depression, psychosis, agitation, and catastrophic reactions, are common in patients with pre-existing cognitive impairment. Detection and management of noncognitive behavioral symptoms associated with MRI and dementia in ICU leads to improved delivery of life-saving critical care.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287-5371, USA. Hochang@jhmi.edu
authors.forename: Hochang B
authors.initials: HB
authors.lastname: Lee
authors.forename: Candyce J
authors.initials: CJ
authors.lastname: DeLoatch
authors.forename: SeongJin
authors.initials: S
authors.lastname: Cho
authors.forename: Paul
authors.initials: P
authors.lastname: Rosenberg
authors.forename: Simon C
authors.initials: SC
authors.lastname: Mears
authors.forename: Frederick E
authors.initials: FE
authors.lastname: Sieber
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D000928:Antidepressive Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000150:complications*; D003693:Delirium / Q000175:diagnosis / Q000188:drug therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D005853:Geriatrics / Q000639:trends*; D006801:Humans; D007362:Intensive Care Units; D001523:Mental Disorders / Q000209:etiology*
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents