title: [An improved case of bedridden mental impairment with normal pressure hydrocephalus associated with acoustic neurinoma after tumor resection].
abstract: A 67-year-old woman developed gait disturbance, dysarthria, cognitive impairment and incontinence at age 65, and became bedridden. She showed mutism, stupor and lower limb spasticity. Cranial CT and MRI revealed marked ventricular enlargement and a cerebellopontine angle tumor. CSF study showed normal pressure (125 mmH2O) and elevated protein (143 mg/dl). Radionuclide cisternography showed redistribution of radionuclide to the ventricles and intraventricular residual radionuclide after 72 hours, which allowed a diagnosis of normal pressure hydrocephalus. After removal of the tumor, ventricle size and CSF protein decreased, and the symptoms of cognitive impairment and motor dysfunction resolved. Histological examination showed acoustic neurinoma. Over the half of hydrocephalus following acoustic neurinoma shows a tendency to improve by surgical resection of the tumor. Neurologists who see cognitively impaired spastic bedridden patients should not overlook this pathology.
authors.affiliation: Department of Neurology, National Hospital Organization Miyazaki Higashi Hospital.
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sugimoto
authors.forename: Akiko
authors.initials: A
authors.lastname: Sugimoto
authors.forename: Kazuko
authors.initials: K
authors.lastname: Saita
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kishi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Shioya
authors.forename: Toshinobu
authors.initials: T
authors.lastname: Higa
mesh_terms: D000368:Aged; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000209:etiology*; D009464:Neuroma, Acoustic / Q000150:complications* / Q000601:surgery