title: The Ayurvedic medicine Clitoria ternatea--from traditional use to scientific assessment.
abstract: Clitoria ternatea L. (CT) (Family: Fabaceae) commonly known as 'Butterfly pea', a traditional Ayurvedic medicine, has been used for centuries as a memory enhancer, nootropic, antistress, anxiolytic, antidepressant, anticonvulsant, tranquilizing and sedative agent. A wide range of secondary metabolites including triterpenoids, flavonol glycosides, anthocyanins and steroids has been isolated from Clitoria ternatea Linn. Its extracts possess a wide range of pharmacological activities including antimicrobial, antipyretic, anti-inflammatory, analgesic, diuretic, local anesthetic, antidiabetic, insecticidal, blood platelet aggregation-inhibiting and for use as a vascular smooth muscle relaxing properties. This plant has a long use in traditional Ayurvedic medicine for several diseases and the scientific studies has reconfirmed those with modern relevance. This review is an effort to explore the chemical constituents, pharmacological and toxicity studies of CT, which have long been in clinical use in Ayurvedic system of medicine along with a critical appraisal of its future ethnopharmacological potential in view of many recent findings of importance on this well known plant species.
authors.affiliation: School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal 700032, India. pulokm@gmail.com
authors.forename: Pulok K
authors.initials: PK
authors.lastname: Mukherjee
authors.forename: Venkatesan
authors.initials: V
authors.lastname: Kumar
authors.forename: N Satheesh
authors.initials: NS
authors.lastname: Kumar
authors.forename: Micheal
authors.initials: M
authors.lastname: Heinrich
mesh_terms: D014151:Anti-Anxiety Agents / Q000737:chemistry / Q000494:pharmacology; D007887:Fabaceae / Q000737:chemistry / Q000187:drug effects; D006801:Humans; D008515:Medicine, Ayurvedic; D008568:Memory / Q000187:drug effects; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018514:Plant Structures / Q000737:chemistry / Q000187:drug effects
chemical_list: D014151:Anti-Anxiety Agents; D010936:Plant Extracts