title: Prognostic significance of myocardial ischemia by dobutamine stress echocardiography in patients without angina pectoris after coronary revascularization.
abstract: The clinical utility of stress testing in patients without angina pectoris after revascularization has been questioned. Dobutamine stress echocardiography (DSE) is an established technique for detection of myocardial ischemia and cardiac risk stratification. We studied the prognostic value of DSE in 393 patients without typical angina pectoris after coronary revascularization. Ischemia was incremental to clinical data in predicting all-cause death (hazard ratio 3.5, 95% confidence interval 1.8 to 6.7) and cardiac death (hazard ratio 4.2, 95% confidence interval 1.8 to 9.8). In conclusion, myocardial ischemia during DSE is independently associated with an increased risk of all-cause mortality and cardiac death in these patients after adjustment for clinical data.
authors.affiliation: Department of Cardiology, Erasmus University Medical Centre, Rotterdam, the Netherlands.
authors.forename: Chiara
authors.initials: C
authors.lastname: Pedone
authors.forename: Abdou
authors.initials: A
authors.lastname: Elhendy
authors.forename: Elena
authors.initials: E
authors.lastname: Biagini
authors.forename: Ron T
authors.initials: RT
authors.lastname: van Domburg
authors.forename: Arend F
authors.initials: AF
authors.lastname: Schinkel
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Di Pasquale
authors.forename: Jeroen J
authors.initials: JJ
authors.lastname: Bax
authors.forename: Don
authors.initials: D
authors.lastname: Poldermans
mesh_terms: D000368:Aged; D000787:Angina Pectoris; D003324:Coronary Artery Disease / Q000628:therapy*; D003643:Death; D025401:Echocardiography, Stress; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000401:mortality* / Q000601:surgery; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment