[Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome].
Takotsubo is a reversible cardiomyopathy, often triggered by a stressful event. It combines clinical features mimicking a myocardial infarction, transient apical ballooning of the left ventricle, normal coronary arteries and a small rise in troponin level. There is a striking female predominance with mean age ranging from 65 to 76 years among series. Preceding stressful event is documented in 50 to 100% of patients. The most common clinical presentation is an angor-like chest pain with ST-segment elevation on the electrocardiogram (70%). The prognosis is excellent even if serious complications may occur: pulmonary oedema, cardiogenic shock, transient dynamic intraventricular gradient, life-threatening arrhythmias. In-hospital mortality is in the range of 0 to 10%. The recurrence rate is low. The precise physiopathology of the syndrome remains unknown but catecholamine mediated myocardial stunning is the most favored explanation.
Leyer
F
F
Service de cardiologie, CHI Le-Raincy-Montfermeil, 10, rue du Général-Leclerc, 93370 Montfermeil, France. fleyer@ch-montfermeil.fr
Nallet
O
O
Cattan
S
S
D006801:Humans; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis / Q000503:physiopathology