title: Insulin producing cells derived from embryonic stem cells: are we there yet?
abstract: Derivation of insulin producing cells (IPCs) from embryonic stem (ES) cells provides a potentially innovative form of treatment for type 1 diabetes. Here, we discuss the current state of the art, unique challenges, and future directions on generating IPCs.
authors.affiliation: Division of Allergy and Immunology, Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
authors.forename: Sudhanshu P
authors.initials: SP
authors.lastname: Raikwar
authors.forename: Nicholas
authors.initials: N
authors.lastname: Zavazava
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology*; D004707:Endoderm / Q000166:cytology; D006801:Humans; D050417:Insulin-Secreting Cells / Q000166:cytology* / Q000637:transplantation; D009928:Organ Specificity; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D014157:Transcription Factors