title: [Clinical and neuroimmunoendocrine effects of doxasosine in treatment of benign hyperplasia of the prostate in elderly people].
abstract: Benign hyperplasia of prostate is a very important not only medical but also social problem. The clinical and neuroimmunoendocrine status of elderly patients with benign hyperplasia of prostate treated by 1-blocker doxasosine is described in this article. Intercellular interactions were examined for tumor necrosis factor a (TNF-alpha), proinflammative interleukine-6 (IL-6), soluble intercellular molecule of adhesion (sICAM). The positive role of doxasosine is demonstrated.
authors.forename: K I
authors.initials: KI
authors.lastname: Proshchaev
authors.forename: V V
authors.initials: VV
authors.lastname: Slivkin
authors.forename: S V
authors.initials: SV
authors.lastname: Filippov
authors.forename: A N
authors.initials: AN
authors.lastname: Il'nitskiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Gileva
authors.forename: V V
authors.initials: VV
authors.lastname: Liutsko
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D000375:Aging / Q000276:immunology*; D015815:Cell Adhesion Molecules / Q000097:blood; D017292:Doxazosin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D011470:Prostatic Hyperplasia / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D014555:Urination Disorders / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000317:Adrenergic alpha-Antagonists; D015815:Cell Adhesion Molecules; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D017292:Doxazosin