title: Meshed capillary vessels by use of narrow-band imaging for differential diagnosis of small colorectal polyps.
abstract: BACKGROUND
  Although microvascular vessels on the surface of colorectal polyps are observed by narrow-band imaging (NBI) with magnification, its clinical usefulness is still uncertain.
  
  
  OBJECTIVE
  Our purpose was to evaluate the usefulness of meshed capillary (MC) vessels observed by NBI magnification for differentiating between nonneoplastic and neoplastic colorectal lesions.
  
  
  METHODS
  Prospective polyp study.
  
  
  METHODS
  National Cancer Center Hospital East, Chiba, Japan.
  
  
  METHODS
  A total of 702 consecutive patients who underwent total colonoscopy between September and December 2004 were prospectively evaluated. Patients with polyps >10 mm and those with polyps previously evaluated by histologic examination or colonoscopy were excluded.
  
  
  METHODS
  Lesions were classified into 2 groups: polyps with invisible or faintly visible MC vessels as nonneoplastic and polyps with clearly visible MC vessels as neoplastic. Lesions judged as nonneoplastic were subjected to biopsy and those as neoplastic were removed endoscopically. Histologic analysis was performed in all lesions.
  
  
  METHODS
  Visible or invisible surface MC vessels, prediction of histologic diagnosis.
  
  
  RESULTS
  Of 92 eligible patients enrolled in this study, 150 lesions, including 39 (26%) hyperplastic polyps and 111 (74%) adenomatous polyps, were detected. Observation of MC vessels detected 107 of 111 neoplastic polyps and 36 of 39 nonneoplastic polyps. The overall diagnostic accuracy, sensitivity, and specificity were 95.3%, 96.4%, and 92.3%, respectively.
  
  
  CONCLUSIONS
  MC vessel judgment performed by a single colonoscopist with extensive experience in magnifying NBI.
  
  
  CONCLUSIONS
  Observation of surface MC vessels by magnifying NBI is a useful and simple method for differentiating colorectal nonneoplastic and neoplastic polyps.
authors.affiliation: Gastrointestinal Center, Sano Hospital, Kobe, Hyogo, Japan. ys_endoscopy@hotmail.com
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sano
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ikematsu
authors.forename: Kuang I
authors.initials: KI
authors.lastname: Fu
authors.forename: Fabian
authors.initials: F
authors.lastname: Emura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Katagiri
authors.forename: Takahiro
authors.initials: T
authors.lastname: Horimatsu
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kaneko
authors.forename: Roy
authors.initials: R
authors.lastname: Soetikno
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Yoshida
mesh_terms: D000328:Adult; D002196:Capillaries / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology; D003111:Colonic Polyps / Q000473:pathology*; D003113:Colonoscopy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000473:pathology; D012680:Sensitivity and Specificity