[Continuous glucose monitoring in type 2 diabetes with gastroparesis].
OBJECTIVE
To observe the glucose profile in type 2 diabetic gastroparesis.


METHODS
31 patients diagnosed with type 2 diabetes were enrolled into this study for measurement of gastric emptying of solids and continuous glucose monitoring to observe blood glucose levels for 72 hours on a balanced diet; the results were compared with 7 subjects with normal glucose regulation.


RESULTS
58.1% of 31 type 2 diabetic patients were found to have delayed gastric emptying of solids. The average glucose level was lower after breakfast [(7.82 +/- 1.42) mmol/L vs (9.35 +/- 2.28) mmol/L, P < 0.01] in the patients with gastroparesis than in those without. Maximal blood glucose level after breakfast [(10.21 +/- 2.17) mmol/L vs (12.24 +/- 2.82) mmol/L, P < 0.01] was lower in the patients with gastroparesis but it reached the peak at a similar time. Two hour AUC was also lower after breakfast in the patients with gastroparesis [(877.62 +/- 272.78) min x mmol x L(-1) vs (1028.40 +/- 283.98) min x mmol x L(-1), P < 0.05].


CONCLUSIONS
Post-prandial glucose level in type 2 diabetic patients with gastroparesis tends to be lower than those without.
Zeng
Wen-Heng
WH
Department of Endocrinology, The Second Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310009, China.
He
Xiao-Wen
XW
Shen
Jie
J
Gu
Wei
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005260:Female; D005746:Gastric Emptying / Q000502:physiology; D018589:Gastroparesis / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period
D001786:Blood Glucose