title: Body cell mass is a useful parameter for assessing malnutrition and severity of disease in non-ascitic cirrhotic patients with hepatocellular carcinoma or esophageal varices.
abstract: Body cell mass (BCM) is a nutritional parameter, however, changes in BCM in patients with non-ascitic liver cirrhosis (LC) in comparison to patients with other malnutritional diseases remains unclear. We investigated the difference in BCM between patients with LC and malnourished gastrointestinal disease controls (M.CON), and examined the relationship between BCM and the severity of LC. Results demonstrated that serum nutritional parameters were not significantly different between the LC (n=56) and M.CON groups (n=25), whereas BCM%BW was significantly lower in the LC group than in the M.CON group (50.9+/-4.6 vs. 54.4+/-7.1%, P=0.018). Furthermore, BCM%BW negatively correlated with the model for end-stage liver disease (MELD) score (P=0.04). In concluson, BCM showed a significant decrease and a negative correlation with the MELD score in the LC group. BCM may be a useful parameter for assessing malnutrition and severity of LC.
authors.affiliation: Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830-0011, Japan. takumi@med.kurume-u.ac.jp
authors.forename: Takumi
authors.initials: T
authors.lastname: Kawaguchi
authors.forename: Eitaro
authors.initials: E
authors.lastname: Taniguchi
authors.forename: Minoru
authors.initials: M
authors.lastname: Itou
authors.forename: Ryoko
authors.initials: R
authors.lastname: Ibi
authors.forename: Teruyo
authors.initials: T
authors.lastname: Okada
authors.forename: Michiko
authors.initials: M
authors.lastname: Mutou
authors.forename: Satomi
authors.initials: S
authors.lastname: Shiraishi
authors.forename: Yuki
authors.initials: Y
authors.lastname: Uchida
authors.forename: Momoka
authors.initials: M
authors.lastname: Otsuka
authors.forename: Youko
authors.initials: Y
authors.lastname: Umeki
authors.forename: Tetsuharu
authors.initials: T
authors.lastname: Oriishi
authors.forename: Hitomi
authors.initials: H
authors.lastname: Hayabuchi
authors.forename: Suiko
authors.initials: S
authors.lastname: Tanaka
authors.forename: Machiko
authors.initials: M
authors.lastname: Takakura
authors.forename: Michio
authors.initials: M
authors.lastname: Sata
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004932:Esophageal and Gastric Varices / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D044342:Malnutrition / Q000473:pathology / Q000503:physiopathology*; D008875:Middle Aged