Chemical characterization and biological activity of essential oils from Daucus carota L. subsp. carota growing wild on the Mediterranean coast and on the Atlantic coast.
The essential oils and supercritical CO(2) extracts of wild Daucus carota L. subsp. carota growing spontaneously in Sardinia and in Portugal were investigated. The main components in the Sardinian essential oil of flowering and mature umbels with seeds are beta-bisabolene (17.6-51.0%) and 11-alpha-(H)-himachal-4-en-1-beta-ol (9.0-21.6%); instead, the oils from Portuguese samples are predominantly composed of geranyl acetate (5.2-65.0%) and alpha-pinene (3.5-37.9%). Supercritical extracts contain lower amounts of monoterpenes and higher amounts of sesquiterpene hydrocarbons. Antifungal activities of the Sardinian oils were the highest, particularly for dermatophytes and Cryptococcus neoformans, with MIC values of 0.16-0.64 microL mL(-1).
Maxia
Andrea
A
Dipartimento di Scienze Botaniche and Co.S.Me.Se, Università degli Studi di Cagliari, Viale Sant'Ignazio, I-09123 Cagliari, Italy.
Marongiu
Bruno
B
Piras
Alessandra
A
Porcedda
Silvia
S
Tuveri
Enrica
E
Gonçalves
Maria J
MJ
Cavaleiro
Carlos
C
Salgueiro
Ligia
L
D000085:Acetates / Q000494:pharmacology; D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents / Q000494:pharmacology*; D000081008:Bicyclic Monoterpenes; D018552:Daucus carota / Q000737:chemistry*; D035264:Flowers; D005658:Fungi / Q000187:drug effects*; D007558:Italy; D008826:Microbial Sensitivity Tests; D000081222:Monocyclic Sesquiterpenes; D039821:Monoterpenes / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011174:Portugal; D012639:Seeds; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology; D013729:Terpenes / Q000494:pharmacology*
C539599:11-alpha-(H)-himachal-4-en-1-beta-ol; D000085:Acetates; D000080462:Acyclic Monoterpenes; D000935:Antifungal Agents; D000081008:Bicyclic Monoterpenes; D000081222:Monocyclic Sesquiterpenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; D013729:Terpenes; C432872:geranyl acetate; C005451:alpha-pinene; C531191:beta-bisabolene