Vaccinia virus in humans and cattle in southwest region of Sao Paulo state, Brazil.
A new outbreak of Vaccinia virus was observed in Southwest region of São Paulo State, Brazil. The disease was observed in four small dairy farms with manual milking. Lesions were detected in cattle and in humans previously vaccinated and not vaccinated against smallpox. Although several reports of Vaccinia virus outbreaks have been occurring in Brazil, it was not yet reported in this region. This outbreak reinforces the viral circulation in our country. The disease in persons previously vaccinated and not vaccinated against smallpox reinforces the absence of immunity, the risk to the human health, and the need for more epidemiologic and immunologic studies.
Megid
Jane
J
University of São Paulo State, School of Veterinary Medicine, Department of Veterinary Hygiene and Public Health, Botucatu, Brazil. jane@fmvz.unesp.br
Appolinário
Camila Michele
CM
Langoni
Hélio
H
Pituco
Edviges Maristela
EM
Okuda
Liria Hiromi
LH
D000818:Animals; D001483:Base Sequence; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D002522:Chlorocebus aethiops; D015605:Cowpox / Q000453:epidemiology* / Q000662:veterinary; D003588:Cytopathogenic Effect, Viral; D017931:DNA Primers; D004279:DNA, Viral / Q000235:genetics; D004196:Disease Outbreaks; D006801:Humans; D008854:Microscopy, Electron; D016273:Occupational Exposure; D016133:Polymerase Chain Reaction; D014616:Vaccinia virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity / Q000648:ultrastructure; D014709:Vero Cells
D017931:DNA Primers; D004279:DNA, Viral