Spectrophotometric determination of muzolimine.
Five simple, rapid and sensitive spectrophotometric procedures for the determination of muzolimine in bulk samples and pharmaceutical dosage forms are described. The methods are based on the formation of coloured species when muzolimine is reacted with 3-methyl-2-benzothiazolinone hydrazone hydrochloride, p-N,N-dimethylphenylenediamine dihydrochloride or p-N-methylaminophenol sulphate and a suitable oxidant or with 2,6-dichloroquinone chlorimide. The results obtained are reproducible with a coefficient of variation of less than 1.5%.
Sastry
C S
CS
Foods and Drugs Laboratory, School of Chemistry, Andhra University, Waltair 530 003, India.
Suryanarayana
M V
MV
Tipirneni
A S
AS
Prasad
T N
TN