Human adult testis-derived pluripotent stem cells: revealing plasticity from the germline.
A recent publication in Nature by Conrad et al. (2008) reports the generation of pluripotent stem cells from isolated human adult testicular germ cells. This work identifies a new source of stem cells for potential autologous therapeutic applications in men.
Payne
Christopher J
CJ
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Braun
Robert E
RE
D000328:Adult; D000367:Age Factors; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology*; D002469:Cell Separation / Q000379:methods; D065150:Cellular Reprogramming / Q000502:physiology*; D019175:DNA Methylation / Q000502:physiology; D006801:Humans; D039503:Integrin alpha6; D053605:Leukemia Inhibitory Factor / Q000378:metabolism; D008297:Male; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism*; D015398:Signal Transduction; D013093:Spermatogonia / Q000166:cytology / Q000378:metabolism*; D033581:Stem Cell Transplantation / Q000379:methods; D013737:Testis / Q000166:cytology*
D039503:Integrin alpha6; D053605:Leukemia Inhibitory Factor