Analytical methodologies for the determination of sertraline.
Sertraline is a widely used antidepressant belonging to the selective serotonin reuptake inhibitor class; its efficacy has been demonstrated not only in the treatment of major depression, obsessive compulsive and panic disorders, but also for eating, premenstrual dysphoric and post-traumatic stress disorders. Several methods have been published for the determination of sertraline in pharmaceuticals, biological materials and environmental samples. The purpose of the current review is to provide a systematic survey of the latest analytical techniques for the determination of sertraline covering the period from 1987 until 2008.
Bosch
M Espinosa
ME
Department of Pharmacy, General Hospital, University Hospital "Virgen del Rocío", Manuel Siurot s/n, 41013 Sevilla, Spain.
Sánchez
A J Ruiz
AJ
Rojas
F Sánchez
FS
Ojeda
C Bosch
CB
D000928:Antidepressive Agents / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000032:analysis*; D017367:Selective Serotonin Reuptake Inhibitors / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D020280:Sertraline / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism
D000928:Antidepressive Agents; D004364:Pharmaceutical Preparations; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline