title: Fluorescence and phosphorescence characteristics of anticoagulants: A new approach to direct measurement of drugs in whole blood.
abstract: Fluorimetric and phosphorimetric excitation and emission peaks and limiting detectable concentrations and phosphorimetric decay times are given for warfarin, dicumarol, diphenandione, phenindione and tromexan. Known concentrations of warfarin, a highly fluorescent compound, and dicumarol, a highly phosphorescent compound, are directly measured in the complex biochemical system of whole blood. Excellent recoveries of warfarin and dicumarol in the concentration range of 0.1 to 10 mg% in whole blood were achieved.
authors.affiliation: University of Florida, Department of Chemistry, Gainesville, Florida 32601, U.S.A.
authors.forename: H C
authors.initials: HC
authors.lastname: Hollifield
authors.forename: J D
authors.initials: JD
authors.lastname: Winefordner