title: [The role of the colposcopy directed cytology and colposcopy directed biopsy in the diagnosis of cervical lesions].
abstract: In the screening of precancer and cancer of the cervix, the colposcopy directed biopsy is the golden standard for finding of intraepithelial lesions and invasive tumours. In the last few years some clinics in the world are trying to substitute the colposcopy directed biopsy for colposcopy directed cytology and in this way they spare financies, time and technology. That is why we decided to summarize our and foreign experience in this field for 10 years period and we examined 300 patients reffered to us for colposcopy and diagnosis of cervical lesions. 80 patients were with normal colposcopy findings. From the rest--220 patients, 70 of them had pathological findings proved by biopsies. By the colposcopy directed brush cytology we had only 20 patients with pathological cytology findings. The sensitivity and specificity of the cytological method were 28% and 98% respectively. When we summarized our experience and that of the foreign clinics we concluded that the colposcopy directed cytology can not substitute the golden standard of the colposcopy directed biopsy and is only a method that gives a signal for further early diagnosis and screening of the precancer and cancer of the uterine cervix.
authors.forename: Stefan
authors.initials: S
authors.lastname: Ivanov
mesh_terms: D001706:Biopsy; D002584:Cervix Uteri / Q000166:cytology / Q000473:pathology; D003127:Colposcopy; D005260:Female; D006801:Humans; D011230:Precancerous Conditions / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D002578:Uterine Cervical Dysplasia / Q000473:pathology*