title: Unilateral granulomatous post-streptococcal uveitis with elevated tension.
abstract: OBJECTIVE
  We document a presumptive case of unilateral post-streptococcal uveitis. The affected eye manifested a granulomatous anterior uveitis with elevated intra-ocular pressure (IOP) compared with the contra-lateral eye. This presentation was preceded by a recent streptococcal pharyngitis.
  
  
  METHODS
  An asymptomatic, otherwise healthy 13-year-old black female presented with anterior chamber cells, mutton fat resembling keratic precipitates, and elevated IOP in the left eye relative to the right eye. The patient had been diagnosed with streptococcal pharyngitis approximately 1 week before her eye examination. A blood chemistry analysis, rheumatoid profile panel and antistreptolysin antibody titer were requested. The patient was prescribed predinisolone acetate 1% ophthalmic suspension in the left eye.
  
  
  RESULTS
  Anti-streptolysin antibody titers were significantly elevated (291 IU/ml). The patient responded favorably to topical ophthalmic steroid treatment with a reduction of IOP and inflammation.
  
  
  CONCLUSIONS
  Unilateral, granulomatous anterior uveitis may be a variant manifestation of post-streptococcal uveitis. The IOP elevation in these cases may result secondary to concurrent trabeculitis.
authors.affiliation: College of Optometry, Nova Southeastern University, Fort Lauderdale, Florida 33162, USA. ebesada@nova.edu
authors.forename: Eulogio
authors.initials: E
authors.lastname: Besada
authors.forename: Barry J
authors.initials: BJ
authors.lastname: Frauens
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000989:Antistreptolysin / Q000097:blood; D005260:Female; D006099:Granuloma / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions; D010612:Pharyngitis / Q000382:microbiology; D011239:Prednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives; D013290:Streptococcal Infections / Q000150:complications*; D014606:Uveitis, Anterior / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology*
chemical_list: D000893:Anti-Inflammatory Agents; D009883:Ophthalmic Solutions; C009935:prednisolone acetate; D000989:Antistreptolysin; D011239:Prednisolone