PMR assay of natural products in pharmaceuticals-III Assay of griseofulvin.
A rapid, accurate and specific PMR method for the determination of griseofulvin in the bulk drug, tablets and dry suspension powder has been developed. The determination is based on the integration of the 4- and 6-methoxy protons of griseofulvin, relative to that of the methyl protons of acetanilide (internal standard).
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Departments of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Riyad University, Riyad, Saudi Arabia.
Hassan
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