Improvement of end-point detection in the non-aqueous titration of sulphacetamide sodium.
The sluggish end-point in the non-aqueous titration of sulphacetamide sodium in glacial acetic acid can be improved by addition of acetic anhydride to the titration medium, and selective determination of sulphacetamide sodium in presence of phenylephrine hydrochloride in eye drops then becomes possible. A mixture of sulphacetamide sodium and the antihistamine drug phenyltoloxamine dihydrogen citrate can also be analysed.
Soliman
S A
SA
College of Medicine & Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Belal
S
S
Bediar
M
M