title: Immunohistochemistry in diagnostic ophthalmic pathology: a review.
abstract: Immunohistochemistry (IHC) is a powerful laboratory technique that employs antibodies to identify cellular components. IHC has revolutionized histopathological diagnosis in the past several decades. This review of IHC in diagnostic ophthalmic pathology will concentrate on common lesions and diagnostic scenarios that frequently are evaluated by IHC in a busy ophthalmic pathology laboratory. Antibodies and markers that are used in the evaluation of ophthalmic lesions will be emphasized.
authors.affiliation: Department of Pathology, Wills Eye Institute, Department of Ophthalmology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19017, USA. reagle@willseye.org
authors.forename: Ralph C
authors.initials: RC
authors.lastname: Eagle
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D003941:Diagnostic Techniques, Ophthalmological; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*
chemical_list: D014408:Biomarkers, Tumor