title: Geometric deformable model driven by CoCRFs: application to optical coherence tomography.
abstract: We present a geometric deformable model driven by dynamically updated probability fields. The shape is defined with the signed distance function, and the internal (smoothness) energy consists of a C1 continuity constraint, a shape prior, and a term that forces the zero-level of the shape distance function towards a connected form. The image probability fields are estimated by our collaborative Conditional Random Field (CoCRF), which is updated during the evolution in an active learning manner: it infers class posteriors in pixels or regions with feature ambiguities by assessing the joint appearance of neighboring sites and using the classification confidence. We apply our method to Optical Coherence Tomography fundus images for the segmentation of geographic atrophies in dry age-related macular degeneration of the human eye.
authors.affiliation: Dept. of Electrical and Computer Engineering, University of Miami, USA. gavriil@miami.edu
authors.forename: Gabriel
authors.initials: G
authors.lastname: Tsechpenakis
authors.forename: Brandon
authors.initials: B
authors.lastname: Lujan
authors.forename: Oscar
authors.initials: O
authors.lastname: Martinez
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gregori
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenfeld
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003198:Computer Simulation; D004548:Elasticity; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008268:Macular Degeneration / Q000473:pathology*; D008954:Models, Biological; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*