A comparative study of injection placentrex and conventional therapy in treatment of pelvic inflammatory disease.
To compare the effect of placentrex injection given along with conventional therapy, with conventional treatment alone on the symptoms and signs of pelvic inflammatory disease (PID) ie, abdominal pain, dysmenorrhoea and adnexal tenderness, 50 out of 100 women with PID were randomly assigned to receive intramuscular placentrex injection along with two-week conventional therapy and 50 received conventional treatment only. Abdominal pain, dysmenorrhoea and adnexal tenderness were evaluated at the end of 2 months. There was marked reduction in the sign of adnexal tenderness in the placentrex group as compared to conventional treatment group (p < 0.001). Subjective symptoms of lower abdominal pain and dysmenorrhoea were also relieved better in placentrex group (p < 0.01 and 0.05 respectively). This study showed significant and persistent improvement of signs and symptoms of PID in women who received injection placentrex.
Garg
R
R
Department of Obstetrics and Gynaecology, Era's Lucknow Medical College, Lucknow 226003.
Zahra
F
F
Chandra
J A
JA
Vatsal
P
P
D015746:Abdominal Pain; D000291:Adnexal Diseases; D000328:Adult; D000477:Alkylating Agents / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D004412:Dysmenorrhea; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy* / Q000503:physiopathology / Q000628:therapy; D010924:Placental Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D014011:Tinidazole / Q000627:therapeutic use; D055815:Young Adult
D000477:Alkylating Agents; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010924:Placental Extracts; D014011:Tinidazole; D008795:Metronidazole; D017963:Azithromycin; D004318:Doxycycline; D007052:Ibuprofen