title: Alkali metals in silica gel (M-SG): a new reagent for desulfonation of amines.
abstract: A novel method for the desulfonation of secondary amines is described. Alkali metals absorbed into nanostructured silica (M-SG) were found to be useful solid-state reagents for the desulfonation of a range of N,N-disubstituted sulfonamides. M-SG reagents are room-temperature-stable free-flowing powders that retain the chemical reactivity of the parent metal, decreasing the danger and associated cost of using reactive metals.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Partha
authors.initials: P
authors.lastname: Nandi
authors.forename: Mikhail Y
authors.initials: MY
authors.lastname: Redko
authors.forename: Kathryn
authors.initials: K
authors.lastname: Petersen
authors.forename: James L
authors.initials: JL
authors.lastname: Dye
authors.forename: Michael
authors.initials: M
authors.lastname: Lefenfeld
authors.forename: Paul F
authors.initials: PF
authors.lastname: Vogt
authors.forename: James E
authors.initials: JE
authors.lastname: Jackson
mesh_terms: D000588:Amines / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D008672:Metals, Alkali / Q000737:chemistry*; D058428:Silica Gel; D012822:Silicon Dioxide / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry*
chemical_list: D000588:Amines; D007202:Indicators and Reagents; D008672:Metals, Alkali; D013449:Sulfonamides; D013451:Sulfonic Acids; D058428:Silica Gel; D012822:Silicon Dioxide