A resected case of solitary pancreatic metastasis from adenocarcinoma of the lung.
BACKGROUND
Primary lung cancer frequently metastasizes to distant organs; however, the pancreas is a relatively infrequent site of metastasis. Because most metastatic cases in the pancreas tend to be discovered in patients only after malignant disease has become widely disseminated, it is extremely rare that a metachronous metastatic lesion limited to the pancreas is discovered with postoperative imaging and is surgically resectable. Most patients demonstrate accompanying metastases to other organs, especially in cases of lung cancer, which prove to be surgically unresectable when diagnosed. Although several cases have been reported of patients who underwent pancreatic resection for curative intent, most patients died from recurrent disease.


METHODS
We report herein an unusual case of secondary tumor of the pancreas (primary tumor: adenocarcinoma of the lung) with hopefully curative resection. The interval between the surgical treatment of lung cancer and the metachronous pancreatic metastasis was 22 months; there has been no recurrence of disease during the 24 months of follow-up after a pylorus-preserving pancreaticoduodenectomy.


CONCLUSIONS
Surgical treatment should be considered in patients with pancreatic metastasis from other organs if the disease is localized in the pancreas or if metastasis in other organs is controlled with chemotherapy and/or radiotherapy.
Mori
Natsuko
N
Department of Internal Medicine, Yokohama Sakae Kyosai Hospital, Yokohama, Japan.
Sawada
Takeshi
T
Satoh
Hiro
H
Kawaguchi
Masahiko
M
Hara
Hiroiku
H
Matsushita
Kazuhiko
K
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001416:Back Pain / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D012008:Recurrence; D020069:Shoulder Pain / Q000209:etiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome