title: C2-symmetric bis-hydrazones as ligands in the asymmetric Suzuki-Miyaura cross-coupling.
abstract: Glyoxal bis-hydrazone derived from (S,S)-1-amino-2,5-diphenylpyrrolidine behaves as an excellent ligand for phosphine-free, asymmetric Suzuki-Miyaura cross couplings, thereby affording a variety of enantiomerically enriched biaryls with different substitution patterns. The high catalytic activity of the [PdCl2(bis-hydrazone)] complex allows reactions to be performed at room temperature, affording products with excellent enantioselectivities in all cases.
authors.affiliation: Departamento de Química Orgánica, Universidad de Sevilla, Apartado de Correos 1203, 41071 Seville, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Bermejo
authors.forename: Abel
authors.initials: A
authors.lastname: Ros
authors.forename: Rosario
authors.initials: R
authors.lastname: Fernández
authors.forename: José M
authors.initials: JM
authors.lastname: Lassaletta