title: Antibody seroprevalences against rabies in dogs vaccinated under field conditions in Bolivia.
abstract: Bolivia currently has one of the highest numbers of cases for human and canine rabies and is thus clue to the elimination process. The objective of the present study was to assess antibody seroprevalences against rabies in dogs vaccinated under field conditions and other factors that might influence the success of the on-going rabies control programmes in an endemic area of the disease, Santa Cruz de la Sierra, Bolivia. All 240 study animals, selected using area-stratified random sampling, were investigated in April 2007. Test prevalences were adjusted for the imperfect test characteristics using the Rogan-Gladen estimator (deterministic and stochastic functions) and Bayesian inference. Ninety-four of the tested 240 vaccinated dogs were classified as test-positive for rabies-specific antibodies. With regard to adjusted overall antibody seroprevalence, Bayesian true prevalence estimates (41%, 95% CI: 37-46%) were lower than both of the Rogan-Gladen estimates. The effect of various epidemiological factors on post-vaccination response was also assessed.
authors.affiliation: Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, Av. 60 y 118, La Plata, B1900AVW, Buenos Aires, Argentina. pvs@provetsur.net
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: M R
authors.initials: MR
authors.lastname: Pecoraro
authors.forename: A
authors.initials: A
authors.lastname: Loza
authors.forename: M
authors.initials: M
authors.lastname: Pérez
authors.forename: G
authors.initials: G
authors.lastname: Ruiz
authors.forename: G
authors.initials: G
authors.lastname: Ascarrunz
authors.forename: L
authors.initials: L
authors.lastname: Rojas
authors.forename: A I
authors.initials: AI
authors.lastname: Estevez
authors.forename: J A
authors.initials: JA
authors.lastname: Guzman
authors.forename: J A C
authors.initials: JA
authors.lastname: Pereira
authors.forename: E T
authors.initials: ET
authors.lastname: González
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001499:Bayes Theorem; D001838:Bolivia / Q000453:epidemiology; D004283:Dog Diseases / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D004285:Dogs; D011818:Rabies / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000276:immunology*; D011820:Rabies virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D014505:Urban Population; D014611:Vaccination / Q000662:veterinary*; D015047:Zoonoses / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D011819:Rabies Vaccines