title: Implementation of a high-sensitivity Micro-Angiographic Fluoroscope (HS-MAF) for in-vivo endovascular image guided interventions (EIGI) and region-of-interest computed tomography (ROI-CT).
abstract: New advances in catheter technology and remote actuation for minimally invasive procedures are continuously increasing the demand for better x-ray imaging technology. The new x-ray high-sensitivity Micro-Angiographic Fluoroscope (HS-MAF) detector offers high resolution and real-time image-guided capabilities which are unique when compared with commercially available detectors. This detector consists of a 300 μm CsI input phosphor coupled to a dual stage GEN2 micro-channel plate light image intensifier (LII), followed by minifying fiber-optic taper coupled to a CCD chip. The HS-MAF detector image array is 1024×1024 pixels, with a 12 bit depth capable of imaging at 30 frames per second. The detector has a round field of view with 4 cm diameter and 35 microns pixels. The LII has a large variable gain which allows usage of the detector at very low exposures characteristic of fluoroscopic ranges while maintaining very good image quality. The custom acquisition program allows real-time image display and data storage. We designed a set of in-vivo experimental interventions in which placement of specially designed endovascular stents were evaluated with the new detector and with a standard x-ray image intensifier (XII). Capabilities such fluoroscopy, angiography and ROI-CT reconstruction using rotational angiography data were implemented and verified. The images obtained during interventions under radiographic control with the HS-MAF detector were superior to those with the XII. In general, the device feature markers, the device structures, and the vessel geometry were better identified with the new detector. High-resolution detectors such as HS-MAF can vastly improve the accuracy of localization and tracking of devices such stents or catheters.
authors.affiliation: Toshiba Stroke Research Center- Division of Radiation Physics, SUNY-University at Buffalo, 3435 Main Street, Buffalo, NY, USA 14214,USA.
authors.forename: C N
authors.initials: CN
authors.lastname: Ionita
authors.forename: C
authors.initials: C
authors.lastname: Keleshis
authors.forename: V
authors.initials: V
authors.lastname: Patel
authors.forename: G
authors.initials: G
authors.lastname: Yadava
authors.forename: K R
authors.initials: KR
authors.lastname: Hoffmann
authors.forename: D R
authors.initials: DR
authors.lastname: Bednarek
authors.forename: A
authors.initials: A
authors.lastname: Jain
authors.forename: S
authors.initials: S
authors.lastname: Rudin