Safety of localizing epilepsy monitoring intracranial electroencephalograph electrodes using MRI: radiofrequency-induced heating.
OBJECTIVE
To investigate heating during postimplantation localization of intracranial electroencephalograph (EEG) electrodes by MRI.


METHODS
A phantom patient with a realistic arrangement of electrodes was used to simulate tissue heating during MRI. Measurements were performed using 1.5 Tesla (T) and 3T MRI scanners, using head- and body-transmit RF-coils. Two electrode-lead configurations were assessed: a "standard" condition with external electrode-leads physically separated and a "fault" condition with all lead terminations electrically shorted.


RESULTS
Using a head-transmit-receive coil and a 2.4 W/kg head-average specific absorption rate (SAR) sequence, at 1.5T the maximum temperature change remained within safe limits (<1 degrees C). Under "standard" conditions, we observed greater heating (<or=2.0 degrees C) at 3T on one system and similar heating (<1 degrees C) on a second, compared with the 1.5T system. In all cases these temperature maxima occurred at the grid electrode. In the "fault" condition, larger temperature increases were observed at both field strengths, particularly for the depth electrodes. Conversely, with a body-transmit coil at 3T significant heating (+6.4 degrees C) was observed (same sequence, 1.2/0.5 W/kg head/body-average) at the grid electrode under "standard" conditions, substantially exceeding safe limits. These temperature increases neglect perfusion, a major source of heat dissipation in vivo.


CONCLUSIONS
MRI for intracranial electrode localization can be performed safely at both 1.5T and 3T provided a head-transmit coil is used, electrode leads are separated, and scanner-reported SARs are limited as determined in advance for specific scanner models, RF coils and implant arrangements. Neglecting these restrictions may result in tissue injury.
Carmichael
David W
DW
Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, and Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom. d.carmichael@ion.ucl.ac.uk
Thornton
John S
JS
Rodionov
Roman
R
Thornton
Rachel
R
McEvoy
Andrew
A
Allen
Philip J
PJ
Lemieux
Louis
L
D001831:Body Temperature / Q000528:radiation effects; D001930:Brain Injuries / Q000209:etiology* / Q000503:physiopathology*; D002056:Burns / Q000209:etiology / Q000503:physiopathology; D004307:Dose-Response Relationship, Radiation; D004567:Electrodes, Implanted / Q000009:adverse effects*; D004569:Electroencephalography / Q000009:adverse effects* / Q000295:instrumentation; D004827:Epilepsy / Q000175:diagnosis*; D019544:Equipment Failure Analysis; D004869:Equipment Safety; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000009:adverse effects*; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000209:etiology* / Q000503:physiopathology*; D011846:Radio Waves