Differences in paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin.
Winefield
Robert D
RD
Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045-7534, USA.
Entwistle
Ruth A
RA
Foland
Travis B
TB
Lushington
Gerald H
GH
Himes
Richard H
RH
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D000077143:Docetaxel; D020128:Inhibitory Concentration 50; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D017239:Paclitaxel / Q000737:chemistry* / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics*; D043823:Taxoids / Q000737:chemistry* / Q000494:pharmacology; D014404:Tubulin / Q000737:chemistry / Q000235:genetics*; D050257:Tubulin Modulators / Q000737:chemistry* / Q000494:pharmacology
D000970:Antineoplastic Agents; D029701:Saccharomyces cerevisiae Proteins; D043823:Taxoids; D014404:Tubulin; D050257:Tubulin Modulators; D000077143:Docetaxel; D017239:Paclitaxel