title: Hantavirus antibodies in rodents and human cases with pulmonary syndrome, Rio Negro, Argentina.
abstract: In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in the region of subantarctic forests. The Andes virus (ANDV) has been identified in the region both in Oligoryzomys longicaudatus rodents and in humans, with the main transmission being from rodents to humans but also showing the possibility of human to human transmission. Between 1996 and 2004, in 40 campaigns, 29.960 night-traps for capturing live rodents were set up. Blood samples were obtained from the rodents and processed using enzyme immunoassay with recombinant antigens made from ANDV. A total of 1767 rodents were captured, with a capture success of 5.9% and an antibody prevalence of 2.1%. Important differences were observed among the species captured from Andes and Steppe regions. Seropositive Oligoryzomys longicaudatus, Abrotrix olivaceus, Abrotrix xanhtothinus and Loxodontomus microtus were captured. During the 1993-2004 period, 40 HPS cases were registered.
authors.affiliation: Facultad de Veterinaria de la Universidad Nacional de La Pampa, and Ministerio de Salud de la Provincia de Río Negro, Laprida 240, Viedma, Río Negro, Argentina. elarrieu@salud.rionegro.gov.ar
authors.forename: Edmundo
authors.initials: E
authors.lastname: Larrieu
authors.forename: Gustavo
authors.initials: G
authors.lastname: Cantoni
authors.forename: Eduardo
authors.initials: E
authors.lastname: Herrero
authors.forename: Alicia
authors.initials: A
authors.lastname: Pérez
authors.forename: Gabriel
authors.initials: G
authors.lastname: Talmon
authors.forename: Gabriela
authors.initials: G
authors.lastname: Vázquez
authors.forename: Odila
authors.initials: O
authors.lastname: Arellano
authors.forename: Paula
authors.initials: P
authors.lastname: Padula
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001118:Argentina / Q000453:epidemiology; D004196:Disease Outbreaks; D004197:Disease Reservoirs; D005260:Female; D006476:Orthohantavirus / Q000276:immunology*; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology* / Q000401:mortality / Q000662:veterinary*; D006801:Humans; D008297:Male; D012376:Rodent Diseases / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D012377:Rodentia / Q000821:virology
chemical_list: D000914:Antibodies, Viral