title: Ossification of the ligamentum flavum in a Caucasian man.
abstract: Abnormal ossification of spinal ligaments is a well-known cause of myelopathy in East Asian populations, with ossification of the ligamentum flavum (OLF) and the posterior longitudinal ligament being the most prevalent. In Caucasian populations, OLF is rare, and there has been only 1 documented case of the disease affecting more than 5 spinal levels. In this report, the authors describe the clinical presentation, imaging characteristics, and management of the second published case of a Caucasian man with OLF affecting almost the entire thoracic spine. The literature is then reviewed with regard to OLF epidemiology, pathogenesis, presentation, and treatment.
authors.affiliation: Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Risheng
authors.initials: R
authors.lastname: Xu
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Sciubba
authors.forename: Ziya L
authors.initials: ZL
authors.lastname: Gokaslan
authors.forename: Ali
authors.initials: A
authors.lastname: Bydon
mesh_terms: D000328:Adult; D006801:Humans; D017843:Ligamentum Flavum; D008297:Male; D017887:Ossification of Posterior Longitudinal Ligament / Q000175:diagnosis* / Q000208:ethnology* / Q000601:surgery; D013904:Thoracic Vertebrae; D044465:White People