Spectrophotometric determination of ketoprofen in pharmaceutical preparations by means of charge transfer complex formation.
A spectrophotometric determination of ketoprofen based upon oxime formation followed by charge transfer complexation with o-chloranil has been developed. Different variables affecting the complexation process have been studied. Beer's law is obeyed in the concentration range 10-80 microg/ml. The method has been successfully applied to the determination of ketoprofen in pure form and in pharmaceutical dosage forms in the presence of its impurities.
El-Sadek
M
M
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig-Egypt.
El-Adl
S
S
Abou-Kull
M
M
Sakr
S M
SM