Iodometric determination of ascorbic acid by controlled potential coulometry.
An iodometric method for the determination of ascorbic acid has been devised. The method is based on previously developed coulometric instrumentation. The stability of different ascorbic acid solutions has been studied and the best conditions have been established. Ascorbic acid has been determined in different kinds of samples but with the main interest on pharmaceutical preparations. Speqial regard has also been paid to the other constituents in such samples, with respect to possible interferences. The error of the coulometric method is about 0.1% and the time of an analysis is in the range 2-6 min.
Karlsson
R
R
Department of Analytical Chemistry, Chemical Center, University of Lund, S-220 07 Lund 7, Sweden.