Clinical application of tobramycin-impregnated calcium sulfate beads in six dogs (2002-2004).
Medical records for six dogs treated with tobramycin-impregnated calcium sulfate beads were reviewed for indications, duration of disease, number of beads implanted, complications, radiographic appearance of the beads, and outcomes. Beads were no longer visible on radiographs made 5 weeks after implantation. Osteomyelitis resolved in five of five dogs with follow-up. The lack of complications and the resolution of clinical signs associated with tobramycin calcium sulfate bead implantation support their clinical application in treating osteomyelitis.
Ham
Kathleen
K
Department of Small Animal Surgery, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood, Urbana, Illinois 61802, USA.
Griffon
Dominique
D
Seddighi
Mohammad
M
Johnson
Ann L
AL
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002133:Calcium Sulfate / Q000737:chemistry; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D016503:Drug Delivery Systems / Q000662:veterinary; D005260:Female; D008297:Male; D008863:Microspheres; D010019:Osteomyelitis / Q000188:drug therapy / Q000662:veterinary*; D013997:Time Factors; D014031:Tobramycin / Q000627:therapeutic use*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D014031:Tobramycin; D002133:Calcium Sulfate