Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions.
Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue. In this paper, we report a multicentric GCT affecting a 41-year-old black woman, with nodules in perineum, groin, vulva, tongue and lip. Some of these lesions were surgically resected, but in a six-year follow-up, new primary lesions and recurrences were observed. In addition, the patient opted to do not remove some of these lesions, but there were not significant intercurrences. In view of the present findings, aspects related to clinical presentation, multiplicity, malignant potential, and treatment of GCT are discussed.
Sargenti-Neto
Sergio
S
Department of Oral Pathology, School of Dentistry, Federal University of Uberlândia, Brazil.
Brazão-Silva
Marco Túllio
MT
do Nascimento Souza
Kelen Christine
KC
de Faria
Paulo Rogério
PR
Durighetto-Júnior
Antônio Francisco
AF
Loyola
Adriano Mota
AM
Cardoso
Sérgio Vitorino
SV
D000328:Adult; D005260:Female; D005833:Genital Neoplasms, Female / Q000601:surgery; D016586:Granular Cell Tumor / Q000473:pathology*; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010502:Perineum / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology*; D014062:Tongue Neoplasms / Q000473:pathology*