Spectrophotometric determination of some benzothiadiazine diuretics with 7,7,8,8-tetracyanoquinodimethane.
A new spectrophotometric method for the determination of some benzothiadiazine drugs is presented, based on reaction with 7,7,8,8-tetracyanoquinodimethane in sodium acetate medium and measurement at 578 nm. Beer's law is obeyed in the concentration range 0.7-6.0 mug/ml for all eight drugs tested.
Mohamed
A M
AM
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.