Studies of 7-hydroxybenzo-4-pyrones.
Spectral data and rates of hydrolysis in 0.7M potassium hydroxide are reported for a series of nine 7-hydroxybenzo-4-pyrones differing in substitution at positions 2 and 3. The results reveal that 2,3-dimethyl substitution produces a molecule, 7-hydroxy-2,3-dimethylchromone, sufficiently fluorescent and resistant to alkaline hydrolysis to warrant its use as the fluorescent moiety in a metallofluorescent indicator of the Calcein Blue type.
Huitink
G M
GM
Department of Chemistry, Indiana University at South Bend, South Bend, Indiana, U.S.A. 46615.