title: A rapid method for the determination of some antihypertensive and antipyretic drugs by thermometric titrimetry.
abstract: A simple and rapid method is described for the direct thermometric determination of milligram amounts of methyl dopa, propranolol hydrochloride, 1-phenyl-3-methylpyrazolone (MPP) and 2,3-dimethyl-1-phenylpyrazol-5-one (phenazone) in the presence of excipients. The compounds are reacted with N'-bromosuccinimide and the heat of reaction is used to determine the end-point of the titration. The time required is approximately 2 min, and the accuracy is analytically acceptable.
authors.affiliation: Department of Analytical Chemistry, Institute of Chemistry University of Sind, Jamshoro, Sind, Pakistan.
authors.forename: U M
authors.initials: UM
authors.lastname: Abbasi
authors.forename: F
authors.initials: F
authors.lastname: Chand
authors.forename: M I
authors.initials: MI
authors.lastname: Bhanger
authors.forename: S A
authors.initials: SA
authors.lastname: Memon