title: Reversed-phase liquid chromatography of alkaloids: Masking effects of inorganic salts.
abstract: The addition of salts (investigated cations Na(+), NH(+)(4), K(+), KBu(+)(4) combined with the anions acetate, Br(-), SCN(-) and I(-)) can be used to eliminate peak tailing and to decrease retention of cationic species in the course of the separation of alkaloids from Chelidonium majus L. by reversed-phase chromatography on a ODS Hypersil column, using water-acetonitrile-methanol mixture as eluent. These findings are interpreted in terms of a silanol masking effect. The extended donor-acceptor concept is used to interpret the effectiveness of different salts in masking the active sites of the stationary phase.
authors.affiliation: Institute of Inorganic Chemistry, Technical University of Vienna, Getreidemarkt 9, A-1060 Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Nowicky
authors.forename: L F
authors.initials: LF
authors.lastname: Han
authors.forename: W
authors.initials: W
authors.lastname: Nowicky
authors.forename: V
authors.initials: V
authors.lastname: Gutmann
authors.forename: W
authors.initials: W
authors.lastname: Linert