A new stilbene glucoside gallate from the roots of Polygonum multiflorum.
A new stilbenoid (1) was isolated from the root extract of Polygonum multiflorum together with eight known constituents (2-9). The chemical structure of 1 was established as the 6''-O-monogalloyl ester of (E)-2,3,4',5-beta-tetrahydroxystilbene-2-beta-D-glucopyranoside based on physicochemical and spectroscopic analyses, particularly by NMR spectroscopic data, i.e., COSY, HMQC and HMBC. Compound 1 weakly inhibited acetylcholinesterase in vitro.
Kim
Hyun Ki
HK
Korea Research Institute of Chemical Technology, Daejeon, 305-606, Korea.
Choi
Yeon Hee
YH
Choi
Jae Seok
JS
Choi
Sang Un
SU
Kim
Young Sup
YS
Lee
Kang Ro
KR
Kim
Young-Kyoon
YK
Ryu
Shi Yong
SY
D000110:Acetylcholinesterase / Q000737:chemistry; D002627:Chemistry, Physical; D002800:Cholinesterase Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight; D018517:Plant Roots / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet
D002800:Cholinesterase Inhibitors; D000110:Acetylcholinesterase