title: Histiocytic sarcoma: PET-CT evaluation of a rare entity.
abstract: Histiocytic sarcoma is a rare malignancy of hematopoietic origin. Lymph nodes, skin, and extranodal sites, especially gastrointestinal tract, are commonly involved. Some cases reported in the past as non-Hodgkin's lymphoma are now classified as histiocytic sarcoma by detailed immunohistochemical studies. Patients with clinically localized disease have a good prognosis whereas those with lymphatic involvement have an aggressive course. In our case, histiocytic sarcoma was detected, originating from the skin over the left shoulder associated with disseminated lymphadenopathy. A positron emission tomography/computed tomography examination was done for evaluating the extent of the disease which showed pathologic increased 18F-fluorodeoxyglucose uptake in the lymph nodes, indicating widespread disease. The pertinent literature is reviewed.
authors.affiliation: Department of Medical Oncology, Gazi University Faculty of Medicine, Besevler, Ankara, 06500, Turkey.
authors.forename: Emel
authors.initials: E
authors.lastname: Yaman
authors.forename: Banu
authors.initials: B
authors.lastname: Ozturk
authors.forename: Ozlem
authors.initials: O
authors.lastname: Erdem
authors.forename: Nahide
authors.initials: N
authors.lastname: Gokcora
authors.forename: Ugur
authors.initials: U
authors.lastname: Coskun
authors.forename: Omer
authors.initials: O
authors.lastname: Uluoglu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Benekli
mesh_terms: D054747:Histiocytic Sarcoma / Q000175:diagnosis*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D035583:Rare Diseases / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed