Simultaneous determination of acetaminophen and dextropropoxyphene napsylate in pharmaceutical preparations by reverse phase HPLC.
The method reported provides a fast, sensitive, accurate and reproducible reverse-phase HPLC assay for acetaminophen and dextropropoxyphene simultaneously. The total elution time is < 5 min. The method is stability-indicating since it can also determine p-aminophenol, a degradation product of acetaminophen, in a concentration as low as 0.005% of the acetaminophen concentration.
Sa'sa'
S
S
Yarmouk University, Irbid, Jordan.
Rashid
A
A
Jalal
I
I