title: Acute coronary syndrome presenting after pseudoephedrine use and regression with beta-blocker therapy.
abstract: Pseudoephedrine, a common ingredient in cold relief drugs, dietary supplements and Chinese herbal tea, has potent sympathomimetic effects, impacting the cardiovascular system. The chemical properties and clinical effects of pseudoephedrine are similar to those of ephedrine, and its main effect is caused by the release of endogenous norepinephrine. A 45-year-old man who presented with chest pain following ingestion of pseudoephedrine--containing prescription medication is described. The patient was initially diagnosed with inferior myocardial infarction based on an electrocardiogram, and intravenous metoprolol was started pending coronary artery angiography. Metoprolol reversed the ST segment elevation and relieved the symptoms, and coronary angiography showed normal coronary arteries. The present case highlights beta-blocker therapy as part of an initial intervention of pseudoephedrine-related cardiac symptoms.
authors.affiliation: howls_castle@mynet.com
authors.forename: Serhat
authors.initials: S
authors.lastname: Akay
authors.forename: Metehan
authors.initials: M
authors.lastname: Ozdemir
mesh_terms: D054058:Acute Coronary Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology; D017023:Coronary Angiography; D004562:Electrocardiography; D004636:Emergency Service, Hospital; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage*; D008875:Middle Aged; D011379:Prognosis; D054199:Pseudoephedrine / Q000008:administration & dosage / Q000009:adverse effects*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D054199:Pseudoephedrine; D008790:Metoprolol