title: Ethnic differences in ST height in the multiethnic study of atherosclerosis.
abstract: BACKGROUND
  ST elevation in precordial leads has been associated with genetic syndromes of arrhythmias and sudden death. ST height data in different ethnic groups are limited.
  
  
  METHODS
  ST height was determined in 4612 African-American, Chinese, Hispanic, and non-Hispanic white men and women aged 45-84 years in the Multiethnic Study of Atherosclerosis (MESA). For leads I, II, and V(1) to V(6,) ST height, measured at the J point and 60 ms after the J point, adjusted for covariates were compared between non-Hispanic white and other ethnic groups using analysis of covariance (ANCOVA).
  
  
  RESULTS
  Among men, ST height was significantly different across all ethnic groups at both time points for all leads (P < 0.01), except at the J point for limb lead II (P = 0.2). Among women, differences were also significant at the J point and 60 ms past the J point (P < 0.01). ST height was lowest for non-Hispanic whites in all leads and at both time points. At the J point, Chinese had the highest ST height for leads V(1) and V(2), whereas African Americans had the greatest ST height for leads I and V(3) to V(6). At 60 ms past the J point, Chinese men had the greatest ST height for lead I and V(1) to V(6;) and Chinese women had greatest ST height for leads V(1) to V(3).
  
  
  CONCLUSIONS
  There were significant differences in ST height among ethnic groups in all ECG leads. The physiological mechanisms and clinical significance of these differences and the possible association with arrhythmias require further study.
authors.affiliation: Cardiovascular Clinical Trials Unit, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Vikram K
authors.initials: VK
authors.lastname: Reddy
authors.forename: Susan M
authors.initials: SM
authors.lastname: Gapstur
authors.forename: Ronald
authors.initials: R
authors.lastname: Prineas
authors.forename: Laura A
authors.initials: LA
authors.lastname: Colangelo
authors.forename: Pamela
authors.initials: P
authors.lastname: Ouyang
authors.forename: Alan H
authors.initials: AH
authors.lastname: Kadish
mesh_terms: D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D001213:Asian; D050197:Atherosclerosis / Q000208:ethnology* / Q000503:physiopathology; D001794:Blood Pressure; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006339:Heart Rate; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008875:Middle Aged; D016277:Ventricular Function, Left