Anticomplementary activity of ergosterol peroxide fromNaematoloma fasciculare and reassignment of NMR data.
A very high content (at least 0.23%) of ergosterol peroxide was isolated fromNaematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the IC(50) values being 5.0 muM and 1.0 muM, respectively. The(1)H and(13)C NMR data of ergosterol peroxide were revised and completely assigned by DEPT,(1)H-(1)H COSY, HMQC and HMBC correlations.
Kim
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DS
Korea Research Institute of Bioscience & Biotechnology, KIST, Yusong P.O. Box 115, 305-600, Taejon, Korea.
Baek
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Oh
S R
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Jung
K Y
KY
Lee
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IS
Kim
J H
JH
Lee
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HK