Orocecal transit time in patients with celiac disease from North India: a case control study.
OBJECTIVE
The mechanisms responsible for bowel disturbances in celiac disease are still unknown. Small bowel motor abnormalities may be involved in this pathological condition; however, there is no study addressing small bowel transit in patients of celiac disease from Northern India.


METHODS
The mouth-to-cecum transit time was studied in 80 celiac patients and 80 age and sex matched apparently healthy controls.


RESULTS
Orocecal transit time in celiac patients was significantly delayed being 180+/-10.6 minutes (Mean+/-SE) as compared to 105+/-12.4 minutes in apparently healthy controls.


CONCLUSIONS
This prolonged orocecal transit time could be due to impaired small bowel function (deranged motility) in patients with celiac disease.
Rana
S V
SV
Department of Gastroentrology, Postgraduate Institute of Medical Education & Research, Chandigarh, India. svrana25@hotmail.com
Sharma
S
S
Sinha
S K
SK
Prasad
K K
KK
Bhasin
D K
DK
Singh
K
K
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002429:Cecal Diseases / Q000503:physiopathology*; D002432:Cecum / Q000503:physiopathology*; D015331:Cohort Studies; D005260:Female; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016065:Myoelectric Complex, Migrating / Q000502:physiology; D055815:Young Adult