Acyclovir delivery systems.
Herpes viruses (herpes simplex, varicella zoster, cytomegalovirus) are the main cause of a wide variety of human infections. Although the development of successful antiviral agents against infections caused by herpes viruses had been slow until the last decade, the production of delivery systems for acyclovir are a promising alternative. The present review summarizes the principal advances made in developing carriers for the delivery of acyclovir by different routes of administration.
Cortesi
Rita
R
University of Ferrara, Department of Pharmaceutical Sciences, CoReS Techno Group, Via Fossato di Mortara, 19-44100 Ferrara, Italy. crt@unife.it
Esposito
Elisabetta
E
D000212:Acyclovir / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D016503:Drug Delivery Systems; D006801:Humans; D011355:Prodrugs; D014777:Virus Diseases / Q000188:drug therapy
D000998:Antiviral Agents; D011355:Prodrugs; D000212:Acyclovir