title: Is GPR39 the natural receptor of obestatin?
abstract: GPR39, an orphan receptor belonging to the family of G protein-coupled receptors, was originally reported to be the receptor of obestatin. However recently, numerous reports have questioned this conclusion. In mammals, GPR39 was reported to be involved in the regulation of gastrointestinal and the metabolic functions. In this article, a latest and brief review on the receptor family, structure, distribution and physiological functions of GPR39 has been reported.
authors.affiliation: College of Yingdong Bioengineering, Shaoguan University, Daxue Avenue, Zhenjiang District, Shaoguan 512005, China.
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Dong
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: He
authors.forename: Sheng-Qiu
authors.initials: SQ
authors.lastname: Tang
authors.forename: Hai-Yun
authors.initials: HY
authors.lastname: Li
authors.forename: Qing-Yan
authors.initials: QY
authors.lastname: Jiang
authors.forename: Xiao-Ting
authors.initials: XT
authors.lastname: Zou
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis; D049109:Cell Proliferation; D004435:Eating; D005769:Gastrointestinal Motility; D054439:Ghrelin / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry* / Q000378:metabolism
chemical_list: C495797:GPR39 protein, human; C512928:GPR39 protein, mouse; D054439:Ghrelin; D043562:Receptors, G-Protein-Coupled