Surface-functionalized silica-coated gold nanoparticles and their bioapplications.
Monodisperse Au at SiO(2) nanoparticles has been functionalized with carboxylic groups for further bioconjugation with amino-terminated oligonucleotides. The oligonucleotide-modified Au at SiO(2) nanoprobes have been applied in the fast colorimetric DNA based on the sequence-specific hybridization properties of DNA. Self-assembling behavior of Au at SiO(2) nanoparticles was also investigated.
Liu
Shuhua
S
Institute of Materials Research & Engineering and Division of Bioengineering, 3 Research Link, Singapore 117602, Singapore.
Zhang
Zhihua
Z
Wang
Yubo
Y
Wang
Fuke
F
Han
Ming-Yong
MY