Bisphosphonated benzoxazinorifamycin prodrugs for the prevention and treatment of osteomyelitis.
Reddy
Ranga
R
Targanta Therapeutics Inc., 7170 Frederick Banting, 2nd Floor, St. Laurent, QC H4S2A1, Canada.
Dietrich
Evelyne
E
Lafontaine
Yanick
Y
Houghton
Tom J
TJ
Belanger
Odette
O
Dubois
Anik
A
Arhin
Francis F
FF
Sarmiento
Ingrid
I
Fadhil
Ibtihal
I
Laquerre
Karine
K
Ostiguy
Valerie
V
Lehoux
Dario
D
Moeck
Gregory
G
Parr
Thomas R
TR
Rafai Far
Adel
A
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry*; D010019:Osteomyelitis / Q000188:drug therapy* / Q000517:prevention & control; D011355:Prodrugs / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry*; D051381:Rats; D012294:Rifamycins / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D011355:Prodrugs; D012294:Rifamycins