title: Hypereosinophilic syndrome in two cats.
abstract: Two cats showing chronic vomiting, diarrhea and weight loss were found to have leukocytosis with marked eosinophilia. Both cats were diagnosed with hypereosinophilic syndrome by the findings of increased eosinophils and their precursors in the bone marrow, eosinophilic infiltration into multiple organs, and exclusion of other causes for eosinophilia. Although cytoreductive chemotherapy with hydroxycarbamide and prednisolone was performed, these two cats died 48 days and 91 days after the initial presentation.
authors.affiliation: Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Takeuchi
authors.forename: Shinobu
authors.initials: S
authors.lastname: Matsuura
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Fujino
authors.forename: Mayumi
authors.initials: M
authors.lastname: Nakajima
authors.forename: Masashi
authors.initials: M
authors.lastname: Takahashi
authors.forename: Ko
authors.initials: K
authors.lastname: Nakashima
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Sakai
authors.forename: Koji
authors.initials: K
authors.lastname: Uetsuka
authors.forename: Koichi
authors.initials: K
authors.lastname: Ohno
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayama
authors.forename: Hajime
authors.initials: H
authors.lastname: Tsujimoto
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001772:Blood Cell Count / Q000662:veterinary; D002371:Cat Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D002415:Cats; D017809:Fatal Outcome; D005260:Female; D006400:Hematocrit / Q000662:veterinary; D006651:Histocytochemistry / Q000662:veterinary; D006918:Hydroxyurea / Q000627:therapeutic use; D017681:Hypereosinophilic Syndrome / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D006918:Hydroxyurea