title: Orthopedic approach of haemophiliacs. A single center experience in Romania.
abstract: Clinical expression of inadequately treated haemophilia is dominated by orthopedic complications, requiring invasive or non-invasive interventions.
  
  
  OBJECTIVE
  In Romania, with under dosed and late introduced "on demand" substitution, we aimed at highlighting the experience of orthopedic treatment and its outcome.
  
  
  METHODS
  Single center retrospective analysis regarding orthopedic interventions and their outcomes was conducted on 59 hemophilia A, B, and von Willebrand disease patients, between 2002 and 2007.
  
  
  RESULTS
  The majority of interventions, invasive (60.71%) and non-invasive (39.28%), were elective, only two being emergencies. Postoperative functional evolution after synovectomies was good in 68.28%, fair in 24.39%, satisfactory in 7.31%. Results of 33 non-invasive (extensive releases) procedures were very good in 27.27%, good in 63.63%, poor in 9.09%.
  The important number and complexity of orthopedic interventions are proving the precarious musculoskeletal state in persons with hemophilia, demonstrating the need of improving substitution, at least with discontinue prophylaxis in patients with severe forms.
authors.affiliation: Childrens Hospital Louis Turcanu, 3rd Pediatric Clinic, Dr. I. Nemoianustreet no 2, Timisoara, 300011, Romania. mserban@spitalcopiitm.ro
authors.forename: M
authors.initials: M
authors.lastname: Serban
authors.forename: M-D
authors.initials: MD
authors.lastname: Mihailov
authors.forename: D
authors.initials: D
authors.lastname: Poenaru
authors.forename: L
authors.initials: L
authors.lastname: Pop
authors.forename: I
authors.initials: I
authors.lastname: Branea
authors.forename: M
authors.initials: M
authors.lastname: Bataneant
authors.forename: A
authors.initials: A
authors.lastname: Lăcătuşu
authors.forename: L
authors.initials: L
authors.lastname: Barna
authors.forename: N
authors.initials: N
authors.lastname: Tepeneu
authors.forename: W
authors.initials: W
authors.lastname: Schramm
mesh_terms: D000768:Anesthesia, General; D006395:Hemarthrosis / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D019637:Orthopedic Procedures; D010146:Pain / Q000209:etiology / Q000503:physiopathology; D016059:Range of Motion, Articular; D012042:Registries; D012189:Retrospective Studies; D012383:Romania; D000074402:Synovectomy