Warthin's tumor at the Brazilian National Cancer Institute: additional evidence of homogeneous sex prevalence and association with other neoplasms.
OBJECTIVE
To report the largest Brazilian series of Warthin's tumor (WT).


METHODS
The medical files of 76 patients with WT treated in the Brazilian National Cancer Institute from 1996 to 2006 were reviewed.


RESULTS
The male:female ratio was 2:1, with a predominance of white, old, and smoking patients. However, there were more women among the nonsmokers. One fifth of the patients presented with synchronous multiple lesions. Parotid lesions were prevalent, but there were patients with lesions in cervical lymph nodes and in the inferior lip. Most cases were treated by superficial parotidectomy, without recurrences. One fourth of the patients also developed other primary neoplasms.


CONCLUSIONS
The observed data do not differ from those in the international literature. Multiplicity and the development of other neoplastic diseases require close clinical management of patients with WT.


CONCLUSIONS
The previously unreported observation of female prevalence among nonsmoking people with WT should be confirmed and explored in future studies.
Cardoso
Sérgio Vitorino
SV
Head and Neck Section and Pathology Division, Brazilian National Cancer Institute, and Oral Pathology Area, Federal University of Uberlândia, Uberlândia, Brazil.
do Nascimento Souza
Kelen Christine
KC
de Faria
Paulo Rogério
PR
Lima
Roberto Araújo
RA
Nascimento
Marilene Filgueira
MF
Eisenberg
Ana Lúcia Amaral
AL
Dias
Fernando Luiz
FL
Loyola
Adriano Mota
AM
D000235:Adenolymphoma / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery*; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001938:Brazil / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000473:pathology; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery*; D015995:Prevalence; D011379:Prognosis; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000453:epidemiology; D016019:Survival Analysis