title: Metal complexes of 1-oxa-4,7,10-triazacyclododecane-N,N',N''-triacetic acid.
abstract: The macrocyclic complexone 1-oxa-4,7,10-triazacyclododecane-N,N',N''-triacetic acid (cODTA) has been synthesized and its protona constants, stability constants of metal complexes and enthalpy changes for the formation of alkaline-earth complexes have been determined. Although it is not so powerful a complexing agent as the N-acetate derivative of the corresponding tetra-aza macrocycle, cDOTA, this is still one of the strongest complexones known, particularly towards the alkaline-earth metals. The complexes of the transition metals are also very stable and there is an inversion of the Irving-Williams order of stability for the complexes of cobalt and nickel.
authors.affiliation: Centro de Quimica Estrutural, Instituto Superior Técnico, Lisbon, Portugal.
authors.forename: M T
authors.initials: MT
authors.lastname: Amorim
authors.forename: R
authors.initials: R
authors.lastname: Delgado
authors.forename: J J
authors.initials: JJ
authors.lastname: da Silva
authors.forename: M
authors.initials: M
authors.lastname: Cândida
authors.forename: T A
authors.initials: TA
authors.lastname: Vaz
authors.forename: M F
authors.initials: MF
authors.lastname: Vilhena