title: Square-edge polymethylmethacrylate intraocular lens design for reducing posterior capsule opacification following paediatric cataract surgery: initial experience.
abstract: OBJECTIVE
  To compare the incidence and severity of development of posterior capsule opacification (PCO) following implantation of square-edged polymethylmethacrylate (PMMA) or hydrophobic acrylic intraocular lenses (IOLs) following paediatric cataract surgery.
  
  
  METHODS
  Prospective, consecutive, interventional, comparative, randomized and cross-sectional study of 40 eyes of 32 children aged between 4 and 12 years who underwent phacoemulsification and posterior chamber IOL implantation.
  
  
  METHODS
  The patients were randomized into two groups of 20 eyes each. Group 1 eyes received a square-edge hydrophobic acrylic IOL (Acrysof SA 60 AT, Alcon Surgical, Fort Worth, Texas), and Group 2 eyes received a square-edge single-piece PMMA lens (Aurolab SQ 3600 Aurolab IOL Division, Madurai, India) in the capsular bag. No eye underwent a primary posterior capsulotomy. The PCO density was evaluated on slitlamp retroillumination photographs by using POCOman software at 3, 6, 9 and 12 months post surgery.
  
  
  RESULTS
  The average percentage PCO on POCOman analysis was 51.23 for Group 1 and 49.49 for Group 2 (P = 0.09), and the average PCO severity grade was 1.34 in Group 1 and 1.12 in Group 2 (P = 0.08). Visual axis remained clear in 14 of 20 eyes with the acrylic lens as compared with 13 of 20 eyes with the PMMA lens. (P = 0.32).
  
  
  CONCLUSIONS
  Square-edge PMMA IOLs offer a significant cost advantage over acrylic lenses at similar rates of PCO formation following paediatric cataract surgery, which is of significant value in developing countries.
authors.affiliation: Grewal Eye Institute, Chandigarh, India.
authors.forename: Gagandeep S
authors.initials: GS
authors.lastname: Brar
authors.forename: Dilraj S
authors.initials: DS
authors.lastname: Grewal
authors.forename: Jagat
authors.initials: J
authors.lastname: Ram
authors.forename: Mohit
authors.initials: M
authors.lastname: Singla
authors.forename: Satinder Pal S
authors.initials: SP
authors.lastname: Grewal
mesh_terms: D000180:Acrylic Resins; D002386:Cataract / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000295:instrumentation / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies
chemical_list: D000180:Acrylic Resins; D019904:Polymethyl Methacrylate