title: [Anesthetic management of the ex-utero intrapartum treatment (EXIT) procedure for giant epignathus and of the tumor excision].
abstract: We report an anesthetic management of the ex-utero intrapartum treatment (EXIT) procedure performed in a fetus with giant epignathus due to laryngeal atresia at 28 weeks' gestation. Anesthesia of the mother was induced with thiamylal and vecuronium, and maintained with 4% sevoflurane in 100% oxygen before delivery. Sevoflurane provided excellent uterine relaxation. To maintain the arterial pressure, the patient received acetate Ringer and ephedrine 4mg. After hysterotomy, a pulse oxymeter and an ultrasound transducer were applied to monitor fetal Sp(O2) and heart rate. No anesthetic agents were injected into the fetus in addition to transplacental sevoflurane. Tracheostomy was performed on the fetus by pediatric surgeons on placental support. The uterine tone improved soon after discontinuing sevoflurane, intramyometrial injection of oxytocin and ergometrine infusion after delivery. Excision of the tumor was performed on day 2 of life. Pediatric surgeons tried to excise it totally, but it was hard to differentiate the tumor from the normal tissue, and partial excision was performed. After the excision, the neonate weighed 944 g and excised specimen weighed 253 g. Though the neonate was immature and the tumor was very large, no perioperative complications were associated with EXIT and the tumor excision.
authors.affiliation: Department of Anesthesiology, Toyohashi Municipal Hospital, Toyohashi 441-8570.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Aoyama
authors.forename: Jun
authors.initials: J
authors.lastname: Nakata
authors.forename: Michiko
authors.initials: M
authors.lastname: Sakakibara
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Takahashi
authors.forename: Masato
authors.initials: M
authors.lastname: Hara
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Megumi
authors.initials: M
authors.lastname: Maseki
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Teramoto
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D005260:Female; D005315:Fetal Diseases / Q000601:surgery*; D005333:Fetus / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D009959:Oropharyngeal Neoplasms / Q000601:surgery*; D011247:Pregnancy; D013724:Teratoma / Q000601:surgery*; D014139:Tracheostomy