title: Binary and ternary complexes of inosine.
abstract: Formation of binary and ternary complexes of Cu(II) and Ni(II) metal ions with inosine as a primary ligand and some biologically important aliphatic and aromatic carboxylic acids (succinic, oxalic, malic, maleic, malonic, tartaric, 5-sulfosalicylic, salicylic and phthalic acids) as secondary ligands was studied by the potentiometric technique at 25 degrees C and 0.10 M (NaNO(3)) ionic strength. The ternary complex formation was found to take place in a stepwise manner. The stability constants of these binary and ternary systems were calculated. The lower stability of 1:2 complexes of inosine compared to the corresponding 1:1 systems is in accord with statistical considerations. The values of Delta log K for the ternary complexes studied have been evaluated and discussed. The mode of chelation of ternary complexes was ascertained by conductivity measurements.
authors.affiliation: Department of Chemistry, Faculty of Science, Cairo University, Beni-Suef Branch, Beni-Suef, Egypt.
authors.forename: M M
authors.initials: MM
authors.lastname: Khalil
authors.forename: A M
authors.initials: AM
authors.lastname: Radalla