Electrochemical oxidation of cisatracurium on carbon paste electrode and its analytical applications.
The electrochemical oxidation of cisatracurium was investigated by cyclic voltammetry and differential pulse voltammetry at a carbon paste electrode and the experimental parameters have been optimized in order to obtain the optimum analytical signal. A differential pulse voltammetric method with carbon paste electrode is described for the determination of cisatracurium with detection limit of 0.38 mug/ml and quantitation limit of 1.26 mug/ml. The proposed method was applied to determine the content of cisatracurium in human urine and human serum, obtaining accurate and precise results.
Torres
R F
RF
Department of Analytical Chemistry, Faculty of Chemistry, University of Seville, 41012 Seville, Spain.
Mochón
M C
MC
Sánchez
J C
JC
Bello López
M A
MA
Pérez
A G
AG