title: Kinetic study of N-bromosuccinimide reactions and kinetic determination of pyridoxine using a bromide-selective electrode.
abstract: The bromide released by the alkaline hydrolysis of N-bromosuccinimide and its reactions with bromide, pyridoxine and thiamine have been studied potentiometrically using a solid-state bromide-selective electrode to monitor the consumed or produced bromide ion. Potential-time indications are obtained using a microcomputer-controlled potentiometric system. The overall rate constants and the activation energies have been calculated. A kinetic-potentiometric procedure for the determination of pyridoxine in the presence of thiamine in pharmaceutical preparations, based on its reaction with N-bromosuccinimide, is presented.
authors.affiliation: Laboratory of Analytical Chemistry, University of Athens, Panepistimiopolis, 157 71, Athens, Greece.
authors.forename: S A
authors.initials: SA
authors.lastname: Halvatzis
authors.forename: M M
authors.initials: MM
authors.lastname: Timotheou-Potamia
authors.forename: C E
authors.initials: CE
authors.lastname: Efstathiou