Frequency and case identification of dementia with Lewy bodies using the revised consensus criteria.
OBJECTIVE
To find the proportion of dementia with Lewy bodies (DLB) in a referral cohort of patients with a first-time diagnosis of mild dementia.


BACKGROUND
The proportion of DLB among the dementia sufferers is not known and the clinical consensus criteria have low sensitivity. We employed the revised DLB criteria to study the proportion with DLB in a community sample of patients with mild dementia.


METHODS
From March 2005 to March 2007, we included 196 patients from referrals to all geriatric medicine, old age psychiatry and neurology outpatient clinics in Rogaland and Hordaland counties in Western Norway. Standardized clinical instruments and diagnostic criteria were employed.


RESULTS
65% had Alzheimer dementia, 20% DLB (16% probable DLB), 5.6% vascular dementia, 5.6% Parkinson disease with dementia, 2.0% frontotemporal dementia and 1.5% alcoholic dementia. There were no significant differences in the proportion with DLB according to age bands and dementia severity groups. The revised criteria for a clinical diagnosis of DLB increased the proportion of probable DLB by 25% compared to the previous criteria.


CONCLUSIONS
DLB is common in patients with mild dementia, and is the second most common type of dementia. The introduction of new clinical criteria for DLB leads to an increase in the proportion diagnosed with probable DLB.
Aarsland
Dag
D
Department of Old Age Psychiatry, Stavanger University Hospital, Bergen, Norway.
Rongve
Arvid
A
Nore
Sabine Piepenstock
SP
Skogseth
Ragnhild
R
Skulstad
Siri
S
Ehrt
Uwe
U
Hoprekstad
Dagne
D
Ballard
Clive
C
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003704:Dementia / Q000145:classification / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007802:Language; D020961:Lewy Body Disease / Q000175:diagnosis* / Q000453:epidemiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D009664:Norway / Q000453:epidemiology; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance; D012015:Reference Standards; D013028:Space Perception / Q000502:physiology; D014796:Visual Perception / Q000502:physiology