title: Streptococcus equi bacteriophage SeP9 binds to group C carbohydrate but is not infective for the closely related S. zooepidemicus.
abstract: Streptococcus equi (S. equi subsp. equi) is widely believed to have evolved from an ancestral strain of S. zooepidemicus (S. equi subsp. zooepidemicus) based on high sequence homology. A striking difference is the absence of phage sequences from S. zooepidemicus. In this study we show that the receptor for SeP9, a temperate bacteriophage of S. equi, is the Lancefield group C carbohydrate. However, although SeP9 binds to group C carbohydrate from S. zooepidemicus, it appears not to replicate and produce plaques.
authors.affiliation: M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546, United States.
authors.forename: Raksha
authors.initials: R
authors.lastname: Tiwari
authors.forename: John F
authors.initials: JF
authors.lastname: Timoney
mesh_terms: D000818:Animals; D002241:Carbohydrates / Q000502:physiology; D002473:Cell Wall / Q000821:virology; D006734:Horse Diseases / Q000382:microbiology*; D006736:Horses; D008242:Lysogeny; D011991:Receptors, Virus / Q000502:physiology; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000662:veterinary*; D013291:Streptococcus / Q000302:isolation & purification / Q000821:virology; D017108:Streptococcus Phages / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D018502:Streptococcus equi / Q000821:virology*; D014779:Virus Replication
chemical_list: D002241:Carbohydrates; D011991:Receptors, Virus