Amphiphilic diarylethene as a photoswitchable probe for imaging living cells.
This communication reports a unique example of water-soluble and fluorescent-switchable amphiphilic diarylethene. This compound performs stable vesicle aggregation in water and shows aggregation-dependent emission in its open form. The fluorescence can be effectively switched by alternating between UV and visible light irradiation. This compound thus can stain KB cells for switchable living cell imaging with excellent resistance to fatigue.
Zou
Ying
Y
Department of Chemistry and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, PR China.
Yi
Tao
T
Xiao
Shuzhang
S
Li
Fuyou
F
Li
Chunyan
C
Gao
Xia
X
Wu
Junchen
J
Yu
Mengxiao
M
Huang
Chunhui
C
D002470:Cell Survival; D005030:Ethylenes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007624:KB Cells; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D055668:Photochemical Processes; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry*
D005030:Ethylenes; D005456:Fluorescent Dyes; D014867:Water; C036216:ethylene