Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis?
Adipocyte/macrophage fatty acid binding protein (A-FABP) has been shown to be closely associated with metabolic syndrome, obesity and development of atherosclerosis. Moreover, A-FABP has been recently suggested as a potential therapeutic target of these abnormalities in animal models. The present review aims to summarize current knowledge on A-FABP functions and regulations both in animal models and humans, since the role of A-FABP in human physiology and disease has not been presently clarified.
Krusinová
Eva
E
Diabetes Centre, Institute for Clinical and Experimental Medicine, Vídenská 1958/9, 14021 Prague, Czech Republic.
Pelikánová
Terezie
T
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D050197:Atherosclerosis / Q000378:metabolism*; D050556:Fatty Acid-Binding Proteins / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D024821:Metabolic Syndrome / Q000378:metabolism*
D050556:Fatty Acid-Binding Proteins