Titrimetric determination of some organic acids by xenon trioxide oxidation.
Aqueous xenon trioxide in acidic or neutral solutions oxidises carboxylic acids quantitatively to carbon dioxide and water. Micro and semimicro amounts of carboxylic acids may be determined by the iodometric titration of the excess of xenon trioxide remaining in the reaction mixture. The optimum time and temperature for the reaction depend on the structure of the acid ; dicarboxylic and hydroxy-carboxylic acids react faster than corresponding monocarboxylic acids. Oxalic and polyhydroxy acids are oxidised within 20 min at room temperature while acetic, maleic, succinic, malonic acids require 2 hr at 40 degrees . Carboxylic acids in amounts less than 100 mug are determined with a coefficient of variation of 4%, which decreases to 1 % for amounts over 250 mug.
Jaselskis
B
B
Department of Chemistry, Loyola University, Chicago, Illinois, U.S.A.
Krueger
R H
RH