title: Silver(I) ion selective ionophores containing dithiocarbamoyl moieties on steroid backbone.
abstract: Tweezer-type and non-tweezer-type ionophores containing dithiocarbamoyl groups on a 7-deoxycholic amide or cholane derivatives were designed and synthesized. Potentiometric evaluation of the poly(vinyl chloride) (PVC) membranes containing those deoxycholic amides/cholanes linked with tweezer-type dithiocarbamoyl moieties showed excellent affinity and selectivity to silver(I) ion over alkali, alkaline earth and other transition metal cations. On the other hand, deoxycholic amides/cholanes substituted with one dithiocarbamoyl group, i.e., non-tweezer-type ionophores, resulted in relatively poor potentiometric sensitivity and detection limits. The enhanced potentiometric properties of newly synthesized tweezer-type dithiocarbamoyl containing ionophores have been further improved by employing silver ion complexing reagent in the internal reference solution, which resulted in greatly reduced detection limit ( approximately 100ppt) for the electrodes based on them.
authors.affiliation: Department of Chemistry, Kwangwoon University, Seoul 139-701, Republic of Korea.
authors.forename: Byeong Hyo
authors.initials: BH
authors.lastname: Kim
authors.forename: Hun Pyo
authors.initials: HP
authors.lastname: Hong
authors.forename: Kui Tae
authors.initials: KT
authors.lastname: Cho
authors.forename: Jeung Hoon
authors.initials: JH
authors.lastname: On
authors.forename: Young Moo
authors.initials: YM
authors.lastname: Jun
authors.forename: In Seok
authors.initials: IS
authors.lastname: Jeong
authors.forename: Geun Sig
authors.initials: GS
authors.lastname: Cha
authors.forename: Hakhyun
authors.initials: H
authors.lastname: Nam