Transanal pull-through rectal amputation for treatment of colorectal carcinoma in 11 dogs.
OBJECTIVE
To evaluate outcome after transanal rectal pull-through amputation of single colorectal adenocarcinoma and in situ carcinoma (Tis) in dogs.


METHODS
Retrospective case series.


METHODS
Dogs (n=11) with colorectal cancer.


METHODS
Full-thickness colorectal amputation by either simple transanal (7 dogs) or combined abdominal-transanal (4) pull-through technique.


RESULTS
Adenocarcinoma (8) and Tis (2) were removed with 3-6 cm of grossly normal tissue, cranial and caudal to the tumor, or in 1 Tis with 2 cm grossly normal tissue, cranial and caudal. Two dogs that had a combined abdominal-transanal approach died within 4 days. In the other dogs, postoperative complications included short-term tenesmus (6 dogs), rectal bleeding (11), rectal stricture (3), and long-term fecal incontinence (1). Postoperative recurrence and metastatic rates for adenocarcinoma were 18.2% and 0%, respectively. Median disease-free interval and survival time were not reached. Mean disease-free and overall survival times were 44.3 and 44.6 months (range, 0-75 months), respectively.


CONCLUSIONS
En bloc excision of colorectal Tis and adenocarcinoma may be followed by a long survival. Complications of the transanal approach are usually moderate and self-limiting, but complications are more common and severe when more extensive resections are performed through a combined abdominal-transanal approach.


CONCLUSIONS
Transanal rectal pull-through amputation is suitable for en bloc resection of colorectal neoplasia. A combined abdominal-transanal approach should be reserved for tumors extending from the mid-cranial region of the rectum to the descending colon.
Morello
Emanuela
E
Dipartimento di Patologia Animale, School of Veterinary Medicine, Turin, Italy.
Martano
Marina
M
Squassino
Chiara
C
Iussich
Selina
S
Caccamo
Roberta
R
Sammartano
Federica
F
Zabarino
Sara
S
Bellino
Claudio
C
Pisani
Guido
G
Buracco
Paolo
P
D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D001003:Anal Canal / Q000601:surgery*; D000818:Animals; D015179:Colorectal Neoplasms / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D018572:Disease-Free Survival; D004283:Dog Diseases / Q000401:mortality / Q000601:surgery*; D004285:Dogs; D005242:Fecal Incontinence / Q000453:epidemiology / Q000662:veterinary; D005260:Female; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D011183:Postoperative Complications / Q000453:epidemiology / Q000662:veterinary; D016896:Treatment Outcome