title: Outcome of antenatally diagnosed fetal anterior abdominal wall defects from a single tertiary centre.
abstract: OBJECTIVE
  The aim of this study was to review the outcome of all cases of antenatally diagnosed anterior abdominal wall defects at a single tertiary centre.
  
  
  METHODS
  41 cases from the database of the Centre of Fetal Care at Queen Charlotte's and Chelsea Hospital in London from 2000 to 2005 were reviewed and both obstetric and neonatal data were collected.
  
  
  RESULTS
  25 cases were exomphalos (61%), 9 were gastroschisis (22%), 6 were body stalk anomaly (15%) and 1 case was cloacal exstrophy (2%). 17 cases (41%) were associated with other major malformations and 4 (10%) were aneuploid. There was 1 case of intrauterine death (2%). Termination of pregnancy was performed in 24 cases (63%). Of the cases that continued (exomphalos and gastroschisis), all babies survived surgery and were discharged home.
  
  
  CONCLUSIONS
  This study demonstrates a high termination rate for fetuses diagnosed with anterior abdominal wall defects. However, the surgical outcome for euploid neonates with isolated exomphalos or gastroschisis appears to be good. Babies with gastroschisis required a longer period of parenteral feeding compared with babies with exomphalos. These infants however had a longer duration of hospitalization.
authors.affiliation: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Arnaoutoglou
authors.forename: L
authors.initials: L
authors.lastname: Pasquini
authors.forename: R
authors.initials: R
authors.lastname: Abel
authors.forename: S
authors.initials: S
authors.lastname: Kumar
mesh_terms: D034861:Abdominal Wall / Q000002:abnormalities*; D000028:Abortion, Induced / Q000706:statistics & numerical data; D000328:Adult; D001746:Bladder Exstrophy / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D016208:Databases, Factual; D005260:Female; D020139:Gastroschisis / Q000175:diagnosis* / Q000453:epidemiology* / Q000601:surgery; D006554:Hernia, Umbilical / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay / Q000706:statistics & numerical data; D008131:London / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011296:Prenatal Diagnosis; D012189:Retrospective Studies; D055815:Young Adult