title: Determination of paracetamol in pharmaceutical formulations using a sequential injection system.
abstract: A simple method for the rapid determination of paracetamol in pharmaceutical formulations is described. The method involves oxidation of paracetamol by potassium hexacyanoferrate(III) and a subsequent reaction with phenol in the presence of ammonia. The blue complex formed is measured at 630 nm. The system has a sample frequency of 27 samples per h with a detection limit of 0.2 mg l(-1). The calibration curve is linear up to 60 mg l(-1) with a relative standard deviation of 1.2% (n=10).
authors.affiliation: Department of Chemistry, University of Pretoria, Pretoria 0002, South Africa.
authors.forename: J Koos F
authors.initials: JK
authors.lastname: van Staden
authors.forename: M Mutshutshu
authors.initials: MM
authors.lastname: Tsanwani