Indirect detection method for flow systems based on perturbation of oxyen reduction at gold and gold chloride electrodes.
A simple scheme for potential indirect electrochemical detection in flow analyses (liquid chromatography and ion chromatography) with experimental examples is presented. The proposed scheme exploits the influence of the analyte on the reduction current of an intrinsic mobile phase additive-oxygen-at the detector electrode, and utilizes the resulting changes in background current as an analytical signal. Several analytes: chloropromazine, ascorbic acid, nitrate and sulfate, cause a shift in the oxygen reduction peak, particularly at the AuCl electrode, that results in a cathodic or anodic shift in the current at a fixed potential.
Tunuli
M S
MS
Department of Chemistry, California State University Northridge, Northridge, CA 91330, U.S.A.