Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature.
Adrenal cystic lesions are uncommon and we analyzed clinical and pathologic features of 25 such cases from a single institute over 23 years. There were 16 pseudocysts, eight endothelial cysts, and one epithelial cyst. Seven of eight endothelial cysts were confirmed to be lymphangiomatous by D2-40 immunostaining. We suggest that pseudocysts and endothelial cysts may have different histogenesis. The proposed mesothelial origin of adrenal epithelial cyst cannot be confirmed in our example. Seven adrenal pseudocysts were associated with tumor, including two pheochromocytomas, one neuroblastoma, one adrenal cortical carcinoma, one adrenal cortical adenoma, one myelolipoma, and one schwannoma. The distinction of true cystic lesion from cystic neoplasm is important and requires thorough sampling of the specimens.
Chien
Hui-Ping
HP
Department of Pathology, Chang Gung Memorial Hospital, No. 5 Fu-Shin Street, Kuei-Shan, Taoyuan, Taiwan, Republic of China.
Chang
Yu-Sun
YS
Hsu
Pei-Sung
PS
Lin
Jen-Der
JD
Wu
Yi-Chin
YC
Chang
Hui-Lang
HL
Chuang
Cheng-Keng
CK
Tsuei
Ke-Hung
KH
Hsueh
Chuen
C
D000307:Adrenal Gland Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003560:Cysts / Q000000981:diagnostic imaging / Q000473:pathology*; D004727:Endothelium / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed