Determination of absolute configurations from vibrational raman optical activity: (trans)-2,3-dimethylthiirane.
Experimental and theoretical vibrational Raman optical activity (VROA) spectra of (2R,3R)-2,3-dimethylthiirane in the 200-1500 cm(-1) region are presented. The level of agreement obtained for the observed and predicted VROA signs suggests that the absolute configurations of chiral molecules can be determined confidently using VROA.
Polavarapu
P L
PL
Department of Chemistry, Vanderbilt University, Nashville, TN 37235, USA.
Pickard
S T
ST
Smith
H E
HE
Black
T M
TM
Barron
L D
LD
Hecht
L
L