title: Spectrophotometric determination of tranexamic acid with chloranil.
abstract: Tranexamic acid is reacted with aqueous alcoholic chloranil, buffered at pH 9, to give a complex with maximum absorption at 346 nm and with an apparent molar absorptivity of 15.7 x 10(3) l.mole(-1).cm(-1). A(max) is linearly related to concentration over the range 2-10 mug ml . When applied to tablets labelled as containing 500 mg each, the mean found was 496 +/- 4 mg. The results were comparable with those of the traditional formol titration method for amino-acids.
authors.affiliation: College of Pharmacy, King Saud University, Pharmaceutical Chemistry Department, Riyadh, Saudi Arabia.
authors.forename: A A
authors.initials: AA
authors.lastname: Wahbi
authors.forename: E A
authors.initials: EA
authors.lastname: Lotfi
authors.forename: H Y
authors.initials: HY
authors.lastname: Aboul-Enein