Hepatic lesions of a standard poodle dog with intrahepatic portosystemic shunt.
A 1-year-and-3-month-old, male standard poodle dog with intrahepatic portosystemic shunt (PSS) was autopsied. Nineteen regions of the liver were prepared for detailed examination, and the distribution of hepatic lesions caused by PSS was studied in the liver of this dog. Histopathologically, the liver revealed a variety of hepatic lesions including lipogranulomas in the hepatic parenchyma, and a ductular reaction and microvascular proliferation in portal areas. The distribution of the lesions was not significantly different among liver regions. It is concluded that, in the present case, hepatic lesions caused by PSS are independent of shunt location, and are distributed equally in the liver.
Isobe
Kaori
K
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Matsunaga
Satoru
S
Nakayama
Hiroyuki
H
Uetsuka
Koji
K
D000818:Animals; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D017809:Fatal Outcome; D007150:Immunohistochemistry / Q000662:veterinary; D008107:Liver Diseases / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D008297:Male; D011168:Portal System / Q000473:pathology* / Q000601:surgery; D011170:Portasystemic Shunt, Surgical / Q000662:veterinary*