title: Postpartum spontaneous rupture of a liver hematoma associated with preeclampsia and HELLP syndrome.
abstract: We report the case of a 28-year-old nulliparous woman who presented at 36 weeks' gestation with preeclampsia: high blood pressure, proteinuria and edema. Serum test results were normal and platelet count was 155 x 10(3)/mm(3). After 30 h the patient initiated severe epigastric pain and vomits, and lab tests presented a slight increase in liver enzymes. The platelet count remained above 150,000/microL. Cesarean section (CS) was performed. Six hours after CS, she developed a hypovolemic shock and lab tests became increasingly abnormal (liver enzymes increased sharply and hemoglobin and platelet count decreased sharply). Abdominal ultrasound showed suggestive signs of hepatic rupture. The patient was stabilized and exploratory laparotomy was performed. Perihepatic packing was applied. The patient was discharged after 25 days of admission (15 days at the ICU) and three explorative laparotomies. This case highlights the unpredictability of this event based on the changes of liver enzyme values, LDH and platelet count. These changes only occurred when the rupture had already occurred and the patient was in hypovolemic shock.
authors.affiliation: Department of Obstetrics and Gynaecology, Alto Ave Hospital Center, Guimarães, Portugal. rfmiguelote@netcabo.pt
authors.forename: Rui Filipe
authors.initials: RF
authors.lastname: Miguelote
authors.forename: Vera
authors.initials: V
authors.lastname: Costa
authors.forename: José
authors.initials: J
authors.lastname: Vivas
authors.forename: Luís
authors.initials: L
authors.lastname: Gonzaga
authors.forename: Carlos Alpoim
authors.initials: CA
authors.lastname: Menezes
mesh_terms: D000328:Adult; D005260:Female; D017359:HELLP Syndrome; D006406:Hematoma / Q000150:complications*; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D049590:Postpartum Period; D011225:Pre-Eclampsia; D011247:Pregnancy; D012422:Rupture, Spontaneous / Q000209:etiology