Lymphocyte subset reconstitution in  pediatric liver recipients induced with  steroid-free rabbit anti-human thymocyte  globulin.
Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence.
Talukdar
Anjan
A
Pediatric Transplantation Laboratory, Hillman Center for Pediatric Transplantation, Childrens Hospital of Pgh and the University of Pittsburgh, Pittsburgh, PA, USA.
AshokKumar
Chethan
C
Farrar
Jennifer
J
Wilson
Patrick
P
Janakiramanan
Arun
A
Tregaskes
Mary
M
Sindhi
Rakesh
R
D000293:Adolescent; D000328:Adult; D000818:Animals; D000961:Antilymphocyte Serum / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008107:Liver Diseases / Q000097:blood* / Q000628:therapy*; D016031:Liver Transplantation / Q000379:methods*; D016131:Lymphocyte Subsets / Q000166:cytology*; D008297:Male; D011817:Rabbits; D013256:Steroids / Q000378:metabolism*; D013602:T-Lymphocytes, Cytotoxic / Q000378:metabolism; D016559:Tacrolimus / Q000008:administration & dosage
D000961:Antilymphocyte Serum; D013256:Steroids; D016559:Tacrolimus