title: Fluorescence optical fiber sensor for tetracycline.
abstract: A new optical fiber sensor for monitoring tetracycline has been described, based on the fluorescence quenching of 1,4-bis(5,5'-dimethylbenzoxazole-1',3'-yl-2')benzene incorporated into a thin plasticized polymer film by tetracycline extracted from aqueous phase into film phase. The sensor is fully reversible and highly reproducible. Furthermore, the sensor exhibits a linear response to tetracycline in the range 6.98x10(-7)-8.73x10(-5) mol l(-1) with a detection limit of 1.06x10(-7) mol l(-1), and with the response time <30 s. The response is also selective to tetracycline, with some common pharmaceutical species, alkali and alkali-earth metal salts being highly discriminated, suggesting that the sensor can be used to monitor tetracycline in three pharmaceutical preparations. The recovery of tetracycline from commercial formulations is 95.3-98.3%.
authors.affiliation: College of Chemistry and Chemical Engineering, Southwest China Normal University, Chongqing 400715, People's Republic of China; College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: W H
authors.initials: WH
authors.lastname: Liu
authors.forename: K M
authors.initials: KM
authors.lastname: Wang
authors.forename: G L
authors.initials: GL
authors.lastname: Shen
authors.forename: R Q
authors.initials: RQ
authors.lastname: Yu