Immobilization of reagents by polymeric materials. Determination of metamizol.
A method for immobilization of inorganic reagents, based on the dispersion of the reagent into an unsaturated polyester solution is applied to immobilization of lead dioxide. The obtained solid is of application in a flow-injection manifold for indirect atomic absorption determination of metamizol in pharmaceutical formulations. The procedure gives a linear calibration graph up to 6 ppm of metamizol with a relative standard deviation of 1.6% (3.0 mg/l) and a sample throughput of 72 hr(-1).
Zamora
L L
LL
Departamento de Química Analítica, Universidad de València, València, Spain.
Calatayud
J M
JM