title: Cutaneous leukocytoclastic vasculitis accompanied by pulmonary tuberculosis.
abstract: We report the case of a 50-year-old male with a rare combination: pulmonary tuberculosis and cutaneous leukocytoclastic vasculitis. The patient sought emergency treatment presenting with headache, arthralgia, cutaneous rash, and weight loss (4 kg) in the last 20 days. A chest X-ray, performed in a previous outpatient visit, revealed cavitation in the middle and upper lobes of the right lung, as confirmed by computed tomography. Sputum smear microscopy (Ziehl-Neelsen staining) was positive in three consecutive samples, and the result of the skin lesion biopsy was consistent with cutaneous leukocytoclastic vasculitis. The patient was therefore diagnosed with cutaneous leukocytoclastic vasculitis accompanied by pulmonary tuberculosis. Our objective was to describe a combination rarely reported in the medical literature and to discuss the possible pathogenic mechanisms of this combination.
authors.affiliation: Federal University of Paraná Hospital de Clínicas, Curitiba, Brazil.
authors.forename: Maurício
authors.initials: M
authors.lastname: Carvalho
authors.forename: Robson Luiz
authors.initials: RL
authors.lastname: Dominoni
authors.forename: Denise
authors.initials: D
authors.lastname: Senchechen
authors.forename: Artur Furlaneto
authors.initials: AF
authors.lastname: Fernandes
authors.forename: Ismael Paulo
authors.initials: IP
authors.lastname: Burigo
authors.forename: Eloisa
authors.initials: E
authors.lastname: Doubrawa
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000473:pathology*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology / Q000473:pathology*