title: Nail changes in pemphigus vulgaris.
abstract: BACKGROUND
  The frequency and types of nail changes in pemphigus vulgaris (PV) are unclear. Aim To determine the frequency and types of nail changes, and their correlation with the number of skin and periungual bullae.
  
  
  METHODS
  Seventy-nine patients with PV, including 59 new patients and 20 patients in relapse, were entered into the study. Microscopic examination in potassium hydroxide and culture for fungus were performed on all clinically abnormal nails.
  
  
  RESULTS
  Twenty-five (31.6%) of 79 patients showed nail changes, with paronychia (n = 8) and onychomadesis (n = 6) being the most common. One patient in relapse had onychomycosis. The frequency of nail changes in fingers affected by periungual bullae was significantly higher than in other fingers (P < 0.05). The number of nail changes was higher in patients with a larger number of skin bullae and in those with a longer duration of disease (P < 0.05).
  
  
  CONCLUSIONS
  Nail changes in PV are common and related to the number of skin bullae and the presence of periungual bullae.
authors.affiliation: Department of Dermatology, Pemphigus Research Unit, Razi Hospital, Tehran University for Medical Sciences, Tehran, Iran.
authors.forename: Mohammadali
authors.initials: M
authors.lastname: Habibi
authors.forename: Hossein
authors.initials: H
authors.lastname: Mortazavi
authors.forename: Shervin
authors.initials: S
authors.lastname: Shadianloo
authors.forename: Kamran
authors.initials: K
authors.lastname: Balighi
authors.forename: S Zahra
authors.initials: SZ
authors.lastname: Ghodsi
authors.forename: Maryam
authors.initials: M
authors.lastname: Daneshpazhooh
authors.forename: Mahin
authors.initials: M
authors.lastname: Valikhani
authors.forename: Akhgar
authors.initials: A
authors.lastname: Ghassabian
authors.forename: Aydin H
authors.initials: AH
authors.lastname: Pooli
authors.forename: Cheyda
authors.initials: C
authors.lastname: Chams-Davatchi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000150:complications / Q000473:pathology*; D009262:Nails / Q000473:pathology; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications; D010392:Pemphigus / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology; D055815:Young Adult