Diastereoselective synthesis of cyclopentanediols by InCl 3/Al mediated intramolecular pinacol coupling reaction in aqueous media.
A "green" and practical intramolecular pinacol coupling reaction promoted by InCl 3/Al catalysts in aqueous media has been developed. Under mild conditions, a novel class of polysubstituted cyclopentane-1,2-diols have been obtained with excellent diastereoselectivity.
Chen
Yunhua
Y
Zhejiang Hisun Pharm. Co. Ltd. Taizhou, PR China.
Wan
Jieping
J
Wang
Chunyan
C
Sun
Cuirong
C
D000535:Aluminum / Q000737:chemistry*; D002384:Catalysis; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D007204:Indium / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry
D003517:Cyclopentanes; D007204:Indium; D014867:Water; C020758:indium trichloride; D000535:Aluminum