title: Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives.
abstract: This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy](+)[PF(6)](-) has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase.
authors.affiliation: Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ 07102, USA.
authors.forename: Chengdong
authors.initials: C
authors.lastname: Zhang
authors.forename: Sanjay V
authors.initials: SV
authors.lastname: Malhotra