title: New colorimetric method for the determination of nystatin.
abstract: A new colorimetric method for the determination of nystatin is reported, based on the reaction of the alkaline hydrolysis product of nystatin with p-aminoacetophenone in presence of concentrated hydrochloric acid. The proposed method determines 0.2-1.0mg of nystatin with recovery of 100.7 +/- 1.2%. The method is adopted to the determination of nystatin in pharmaceutical preparations, and interference due to the presence of sugar is eliminated.
authors.affiliation: Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
authors.forename: M M
authors.initials: MM
authors.lastname: Amer
authors.forename: A A
authors.initials: AA
authors.lastname: Habeeb