Urea as the basic component in pyridine-free Karl Fischer reagent.
A solution of urea, sulphur dioxide and sodium salicylate in methanol is proposed as the solvent in the Karl Fischer titration, with a separate iodine solution as titrant. Comparison of the performance of this solvent with that of some commercial reagents shows that it is has distinct advantages for use with amine samples.
Bos
M
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Department of Chemical Technology, Technical University Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.