VirusMINT: a viral protein interaction database.
Understanding the consequences on host physiology induced by viral infection requires complete understanding of the perturbations caused by virus proteins on the cellular protein interaction network. The VirusMINT database (http://mint.bio.uniroma2.it/virusmint/) aims at collecting all protein interactions between viral and human proteins reported in the literature. VirusMINT currently stores over 5000 interactions involving more than 490 unique viral proteins from more than 110 different viral strains. The whole data set can be easily queried through the search pages and the results can be displayed with a graphical viewer. The curation effort has focused on manuscripts reporting interactions between human proteins and proteins encoded by some of the most medically relevant viruses: papilloma viruses, human immunodeficiency virus 1, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, herpes viruses and Simian virus 40.
Chatr-aryamontri
Andrew
A
Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.
Ceol
Arnaud
A
Peluso
Daniele
D
Nardozza
Aurelio
A
Panni
Simona
S
Sacco
Francesca
F
Tinti
Michele
M
Smolyar
Alex
A
Castagnoli
Luisa
L
Vidal
Marc
M
Cusick
Michael E
ME
Cesareni
Gianni
G
D003196:Computer Graphics; D030562:Databases, Protein; D025941:Protein Interaction Mapping; D014764:Viral Proteins / Q000378:metabolism*
D014764:Viral Proteins