The use of stabilizers in the UV assay of ascorbic acid.
Sodium thiosulphate (0.04%w/v) has been used to stabilize ascorbic acid in aqueous medium. The method has been used to assay ascorbic acid in commercial tablet preparations. It is very accurate, precise and reproducible. It compares favourably with official titrimetric method. The method is simple and can be adopted for the routine assay of ascorbic acid in single component tablet formulations.
Kwakye
J K
JK
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Science and Technology, Kumasi, Ghana.