title: Analytical methodologies for the determination of sertraline.
abstract: Sertraline is a widely used antidepressant belonging to the selective serotonin reuptake inhibitor class; its efficacy has been demonstrated not only in the treatment of major depression, obsessive compulsive and panic disorders, but also for eating, premenstrual dysphoric and post-traumatic stress disorders. Several methods have been published for the determination of sertraline in pharmaceuticals, biological materials and environmental samples. The purpose of the current review is to provide a systematic survey of the latest analytical techniques for the determination of sertraline covering the period from 1987 until 2008.
authors.affiliation: Department of Pharmacy, General Hospital, University Hospital "Virgen del Rocío", Manuel Siurot s/n, 41013 Sevilla, Spain.
authors.forename: M Espinosa
authors.initials: ME
authors.lastname: Bosch
authors.forename: A J Ruiz
authors.initials: AJ
authors.lastname: Sánchez
authors.forename: F Sánchez
authors.initials: FS
authors.lastname: Rojas
authors.forename: C Bosch
authors.initials: CB
authors.lastname: Ojeda
mesh_terms: D000928:Antidepressive Agents / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000032:analysis*; D017367:Selective Serotonin Reuptake Inhibitors / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D020280:Sertraline / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism
chemical_list: D000928:Antidepressive Agents; D004364:Pharmaceutical Preparations; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline