Quantitative determination of esters by saponification in dimethyl sulphoxide.
A method is given for the quantitative determination of esters which makes use of the unusually rapid rate of their alkaline hydrolysis in aqueous dimethyl sulphoxide medium. Only 5 min heating on a steam-bath is needed for quantitative hydrolysis of most esters, and many react completely in 5 min at room temperature. When hydrolysis is complete, the excess of base is titrated with standard acid, using a visual indicator.
Vinson
J A
JA
Institute for Atomic Research and Department of Chemistry Iowa State University, Ames, Iowa, U.S.A.
Fritz
J S
JS
Kingsbury
C A
CA