title: First demonstration of an increased serum level of reactive oxygen species during the peripartal period in the ewes.
abstract: Reactive Oxygen Species (ROS) are produced during oxidative metabolism, and regulate many biological processes. The acute inflammation characterizing parturition induces many physiological changes. Among them, there is evidence that ROS affect the synthesis of many factors involved in parturition. Our study aims to determine serum levels of ROS in periparturient ewes, as well as to establish a value of reference of their physiological concentration. ROS determination was performed on blood collected every 12 hours in periparturient twin pregnant ewes. Our results will show a significant increase in ROS concentrations from the beginning to the end of the experiment. This increase may be due to the inflammatory process establishing during parturition.
authors.affiliation: Department of Animal Production, Faculty of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
authors.forename: Annalisa
authors.initials: A
authors.lastname: Rizzo
authors.forename: Maddalena
authors.initials: M
authors.lastname: Mutinati
authors.forename: Massimo
authors.initials: M
authors.lastname: Spedicato
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Minoia
authors.forename: Carmelinda
authors.initials: C
authors.lastname: Trisolini
authors.forename: Felicita
authors.initials: F
authors.lastname: Jirillo
authors.forename: Raffaele Luigi
authors.initials: RL
authors.lastname: Sciorsci
mesh_terms: D000818:Animals; D016207:Cytokines / Q000097:blood / Q000502:physiology; D005260:Female; D018384:Oxidative Stress / Q000276:immunology; D036801:Parturition / Q000097:blood / Q000276:immunology*; D049590:Postpartum Period / Q000097:blood / Q000276:immunology; D011247:Pregnancy; D017382:Reactive Oxygen Species / Q000097:blood*; D034561:Sheep, Domestic / Q000097:blood / Q000276:immunology*; D013997:Time Factors; D015854:Up-Regulation / Q000276:immunology
chemical_list: D016207:Cytokines; D017382:Reactive Oxygen Species