title: Deprotonative cadmation of functionalized aromatics.
abstract: This communication describes the deproto-metalation of a large range of aromatics including heterocycles using a newly developed lithium-cadmium base; the reaction proceeds at room temperature with an excellent chemoselectivity and efficiency, and proved to be regioselective in most cases.
authors.affiliation: Chimie et Photonique Moléculaires, UMR 6510 CNRS, Université de Rennes 1, Campus Scientifique de Beaulieu, Rennes Cedex, France.
authors.forename: Jean-Martial
authors.initials: JM
authors.lastname: L'Helgoual'ch
authors.forename: Ghenia
authors.initials: G
authors.lastname: Bentabed-Ababsa
authors.forename: Floris
authors.initials: F
authors.lastname: Chevallier
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Yonehara
authors.forename: Masanobu
authors.initials: M
authors.lastname: Uchiyama
authors.forename: Aïcha
authors.initials: A
authors.lastname: Derdour
authors.forename: Florence
authors.initials: F
authors.lastname: Mongin
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D002104:Cadmium / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis* / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011522:Protons; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D001555:Benzene Derivatives; D006571:Heterocyclic Compounds; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D011522:Protons; D002104:Cadmium; D008094:Lithium