Preventing the spread of malaria and dengue fever using genetically modified mosquitoes.
In this candid interview, Anthony A. James explains how mosquito genetics can be exploited to control malaria and dengue transmission. Population replacement strategy, the idea that transgenic mosquitoes can be released into the wild to control disease transmission, is introduced, as well as the concept of genetic drive and the design criterion for an effective genetic drive system. The ethical considerations of releasing genetically-modified organisms into the wild are also discussed.
James
Anthony A
AA
Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.
D000818:Animals; D030801:Animals, Genetically Modified; D009033:Culicidae / Q000235:genetics*; D003715:Dengue / Q000517:prevention & control*; D006801:Humans; D008288:Malaria / Q000517:prevention & control*; D011157:Population Dynamics