title: Capillary malformation associated with angiolipoma: analysis of 127 consecutive clinic patients.
abstract: BACKGROUND
  Capillary malformations (also known as port-wine stains) are low-flow vascular malformations of the skin that occur in 0.3% of neonates. Angiolipomas are subcutaneous, benign, usually multiple, lesions, composed of adipose tissue and blood vessels, which occur in young adults.
  
  
  OBJECTIVE
  The aims of this study were to determine whether there is an association between capillary malformations and angiolipoma, and to describe the characteristics of patients with this association.
  
  
  METHODS
  Prompted by our finding of an accompanying subcutaneous mass in a patient with capillary malformation, we reviewed the entire pool of 127 patients (71 women, 56 men; average age 22.2 years) attending the Rabin Medical Center (Petach Tikva, Israel) for treatment of nonfacial capillary malformations. All patients underwent a detailed history and comprehensive physical examination. Biopsy samples were taken from suspect lesions.
  
  
  RESULTS
  In addition to the index patient, four patients were found to have a subcutaneous mass beneath the capillary formation. Imaging and histologic studies identified the mass as an angiolipoma. All of the lesions were relatively refractory to pulsed dye laser or intense pulsed light treatment.
  
  
  CONCLUSIONS
  This unique report of an association between capillary malformation and angiolipoma is intended to raise the index of suspicion for underlying angiolipoma in clinicians treating patients with refractory nonfacial capillary malformations.
authors.affiliation: Laser Unit, Department of Dermatology, Rabin Medical Center, Petach Tikva, Israel. alapidot@netvision.net.il
authors.forename: Moshe
authors.initials: M
authors.lastname: Lapidoth
authors.forename: Dan
authors.initials: D
authors.lastname: Ben Amitai
authors.forename: Meora
authors.initials: M
authors.lastname: Feinmesser
authors.forename: Lehavit
authors.initials: L
authors.lastname: Akerman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018206:Angiolipoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001706:Biopsy; D002196:Capillaries / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D019339:Port-Wine Stain / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies; D012867:Skin / Q000098:blood supply; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D055815:Young Adult