Cu(I)-catalyzed hetero-Diels-Alder reaction between Danishefsky-type siloxy dienes and ketones.
A general catalytic method for the hetero-Diels-Alder reaction between Danishefsky-type siloxy dienes and ketones was developed. Optimum results were produced with a catalyst generated from CuOTf x (C6H6)1/2 and TBAT with Ph 3PO as the catalytic additive. This reaction was extended to an asymmetric variant, using a Cu(I)-Walphos catalyst.
Chen
I-Hon
IH
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Oisaki
Kounosuke
K
Kanai
Motomu
M
Shibasaki
Masakatsu
M
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D012833:Siloxanes / Q000737:chemistry*
D000475:Alkenes; D007659:Ketones; D012833:Siloxanes; D003300:Copper