title: Determination of methotrexate in human blood plasma by adsorptive stripping voltammetry.
abstract: The use of adsorptive stripping voltammetry to measure sub-micromolar concentrations of methotrexate in plasma has been investigated. A simple clean-up procedure has been developed in which methotrexate is extracted from blood plasma with Amberlite XAD-2, which is a non-ionic resin, and eluted with methanol. Recovery for plasma analysis was 80%.
authors.affiliation: Department of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Temizer
authors.forename: A
authors.initials: A
authors.lastname: Nur Onar