Chemical components of urinary stones according to age and sex of adult patients.
OBJECTIVE
Report the relationship of composition with age and sex of the patients.


METHODS
A series of 426 urinary stones, 33 from the lower (LUT) and 393 from the upper urinary tract (UUT) of adults, were analyzed for their chemical composition using infrared spectroscopy. The majority of LUT stones were from males (n = 26) and in the age group beyond 60 years (n = 20).


RESULTS
Calcium oxalate (CaOx) and uric acid and urate (UA-UR) were the main constituents in LUT stones of males and UA-UR and magnesium ammonium phosphate (MAP) of females. While UA-UR was distributed in all age group of males, it was only detected in elderly females. In cases of UUT stones, the peak finding for both sexes was for the 50-59-year-olds (age class). The MAP component was found more commonly in UUT stones of females, particularly in the younger age groups. CaOx and calcium phosphate (CaP) were the main components of UUT stones in both sexes (CaP was slightly more common in females) with the highest proportion in the 30-49-year-olds (age class), thereafter they declined and were replaced with UA-UR.


CONCLUSIONS
Although the proportion of LUT stones in the present study was small, the present findings agree with previous studies on the role of both age and sex in the etiopathogeny of urinary stones.
Prasongwatana
Vitoon
V
Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Bovornpadungkitti
Sombat
S
Chotikawanich
Ekkarin
E
Pachitrat
Kachit
K
Suwanatrai
Sunthon
S
Sriboonlue
Pote
P
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002129:Calcium Oxalate; D005260:Female; D006801:Humans; D017616:Magnesium Compounds; D008297:Male; D008875:Middle Aged; D010710:Phosphates; D010865:Pilot Projects; D012307:Risk Factors; D012737:Sex Factors; D013055:Spectrophotometry, Infrared; D000069877:Struvite; D013785:Thailand; D014527:Uric Acid; D014545:Urinary Calculi / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D055815:Young Adult
D017616:Magnesium Compounds; D010710:Phosphates; D002129:Calcium Oxalate; D014527:Uric Acid; D000069877:Struvite