title: Simple and rapid determination of the drug naproxen in pharmaceutical preparations by heavy atom-induced room temperature phosphorescence.
abstract: A simple, selective and sensitive heavy atom-induced room temperature phosphorimetric method (HAI-RTP) is described for the determination of naproxen (NAP) in pharmaceutical preparations. The phosphorescence signals are a consequence of intermolecular protection when analytes are, exclusively, in presence of a heavy atom salt and sodium sulfite as an oxygen scavenger to minimize RTP quenching. These variables selection constitute the basis of a HAI-RTP method for the determination of naproxen (detection limit 17.6 ng ml(-1); 1.71% relative standard deviation at 250 ng ml(-1)). The method has been applied satisfactorily to the analysis of pharmaceutical preparations.
authors.affiliation: Department of Analytical Chemistry, Faculty of Sciences, University of Granada, C/Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Segura Carretero
authors.forename: C
authors.initials: C
authors.lastname: Cruces-Blanco
authors.forename: M I
authors.initials: MI
authors.lastname: Ramírez García
authors.forename: B
authors.initials: B
authors.lastname: Cañabate Díaz
authors.forename: A
authors.initials: A
authors.lastname: Fernández Gutiérrez