title: Transanal pull-through rectal amputation for treatment of colorectal carcinoma in 11 dogs.
abstract: OBJECTIVE
  To evaluate outcome after transanal rectal pull-through amputation of single colorectal adenocarcinoma and in situ carcinoma (Tis) in dogs.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Dogs (n=11) with colorectal cancer.
  
  
  METHODS
  Full-thickness colorectal amputation by either simple transanal (7 dogs) or combined abdominal-transanal (4) pull-through technique.
  
  
  RESULTS
  Adenocarcinoma (8) and Tis (2) were removed with 3-6 cm of grossly normal tissue, cranial and caudal to the tumor, or in 1 Tis with 2 cm grossly normal tissue, cranial and caudal. Two dogs that had a combined abdominal-transanal approach died within 4 days. In the other dogs, postoperative complications included short-term tenesmus (6 dogs), rectal bleeding (11), rectal stricture (3), and long-term fecal incontinence (1). Postoperative recurrence and metastatic rates for adenocarcinoma were 18.2% and 0%, respectively. Median disease-free interval and survival time were not reached. Mean disease-free and overall survival times were 44.3 and 44.6 months (range, 0-75 months), respectively.
  
  
  CONCLUSIONS
  En bloc excision of colorectal Tis and adenocarcinoma may be followed by a long survival. Complications of the transanal approach are usually moderate and self-limiting, but complications are more common and severe when more extensive resections are performed through a combined abdominal-transanal approach.
  
  
  CONCLUSIONS
  Transanal rectal pull-through amputation is suitable for en bloc resection of colorectal neoplasia. A combined abdominal-transanal approach should be reserved for tumors extending from the mid-cranial region of the rectum to the descending colon.
authors.affiliation: Dipartimento di Patologia Animale, School of Veterinary Medicine, Turin, Italy.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Morello
authors.forename: Marina
authors.initials: M
authors.lastname: Martano
authors.forename: Chiara
authors.initials: C
authors.lastname: Squassino
authors.forename: Selina
authors.initials: S
authors.lastname: Iussich
authors.forename: Roberta
authors.initials: R
authors.lastname: Caccamo
authors.forename: Federica
authors.initials: F
authors.lastname: Sammartano
authors.forename: Sara
authors.initials: S
authors.lastname: Zabarino
authors.forename: Claudio
authors.initials: C
authors.lastname: Bellino
authors.forename: Guido
authors.initials: G
authors.lastname: Pisani
authors.forename: Paolo
authors.initials: P
authors.lastname: Buracco
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D001003:Anal Canal / Q000601:surgery*; D000818:Animals; D015179:Colorectal Neoplasms / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D018572:Disease-Free Survival; D004283:Dog Diseases / Q000401:mortality / Q000601:surgery*; D004285:Dogs; D005242:Fecal Incontinence / Q000453:epidemiology / Q000662:veterinary; D005260:Female; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D011183:Postoperative Complications / Q000453:epidemiology / Q000662:veterinary; D016896:Treatment Outcome