title: [Study on optimization of the hydrolysis process of dioscin catalyzed by hydrochloric acid].
abstract: OBJECTIVE
  To study the optimization of hydrolysis process of dioscin catalyzed by hydrochloric acid.
  
  
  METHODS
  The effects of hydrochloric acid concentration, reaction temperature, reaction time and their interactions had been investigated using orthogonal design and single-factor experiments.
  
  
  RESULTS
  The optimum hydrolysis conditions were as follows: reaction temperature 90 degrees C, reaction time 3h, hydrochloric acid concentration 2.0 mol/L.
  
  
  CONCLUSIONS
  Hydrochloric acid concentration and reaction temperature should be controlled because of their remarkable influence on hydrolysis process.
authors.affiliation: Institute of Fine Chemistry and Engineering, Kaifeng 475001, China. liq@henu.edu.cn
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.forename: Xiang-Tao
authors.initials: XT
authors.lastname: Gao
authors.forename: Wen-Lei
authors.initials: WL
authors.lastname: Zhao
authors.forename: Xiu-Hua
authors.initials: XH
authors.lastname: Liu
mesh_terms: D000704:Analysis of Variance; D002384:Catalysis; D027742:Dioscorea / Q000737:chemistry*; D004144:Diosgenin / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D006851:Hydrochloric Acid / Q000737:chemistry*; D006868:Hydrolysis; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D004144:Diosgenin; D006851:Hydrochloric Acid