Determination of indomethacin in urine using molecule imprinting-chemiluminescence method.
A soluble Mn (IV)-formaldehyde-indomethacin chemiluminescence system was found. Using a synthesized indomethacin MIP as recognition material and soluble Mn (IV)-formaldehyde-indomethacin as detection system, a new molecule imprinted-chemiluminesence method of determination of indomethacin was established. The response range of this method was between 1.0x10(-7) and 1.0x10(-5)g/mL with a linear correlation coefficient of 0.994. The detection limit was 4x10(-8)g/mL. The relative standard deviation for 5.0x10(-7)g/mL of indomethacin solution was 3.1% (n=7).
Nie
Fei
F
School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, PR China.
Lu
Jiuru
J
He
Yunhua
Y
Du
Jianxiu
J