Tin-free enantioselective radical reactions using silanes.
Readily available hexyl silane is an excellent choice as a H-atom donor and a chain carrier in Lewis acid mediated enantioselective radical reactions. Conjugate radical additions to alpha,beta-unsaturated imides at room temperature proceed in good yields and excellent enantioselectivities.
Sibi
Mukund P
MP
Department of Chemistry, North Dakota State University, Fargo, North Dakota 58105, USA. mukund.sibi@ndsu.edu
Yang
Yong-Hua
YH
Lee
Sunggi
S
D005609:Free Radicals / Q000737:chemistry; D007094:Imides / Q000737:chemistry; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity; D014001:Tin
D005609:Free Radicals; D007094:Imides; D012821:Silanes; D014001:Tin