Factors associated with impaired quality of life in younger and older adults with epilepsy.
The purpose of this study is to weigh psychological state, patients' demographics, seizure-related factors, and medical comorbidity in older adults with epilepsy against the same parameters in younger adults in an attempt to identify best quality of life (QoL) predictors. The Quality of Life in Epilepsy Inventory for Adults (QOLIE-31) and the Beck Depression Inventory-II (BDI-II) were completed by 146 patients with localization-related epilepsy. There was no statistical difference in the QOLIE-31 total score between younger and older adults. Best QoL predictors were BDI-II and seizure frequency, with BDI-II providing more than 3 times the impact of seizure frequency. BDI-II also substantively predicted most QOLIE-31 domains. Additionally, epilepsy duration positively correlated with overall QoL only among older adults. In summary, in younger as well as older adult epilepsy patients, depressive symptoms emerge as the strongest predictor of QoL. However, older adults appear to adapt better to their chronic health problem.
Canuet
Leonides
L
Department of Clinical Neuroscience and Psychiatry, Osaka University Graduate School of Medicine, Japan.
Ishii
Ryouhei
R
Iwase
Masao
M
Ikezawa
Koji
K
Kurimoto
Ryu
R
Azechi
Michiyo
M
Takahashi
Hidetoshi
H
Nakahachi
Takayuki
T
Teshima
Yoshio
Y
Takeda
Masatoshi
M
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003627:Data Interpretation, Statistical; D003863:Depression / Q000523:psychology; D004827:Epilepsy / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012640:Seizures / Q000523:psychology