title: Micro- and nanofluidic systems for high-throughput biological screening.
abstract: High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom.
authors.forename: Jongin
authors.initials: J
authors.lastname: Hong
authors.forename: Joshua B
authors.initials: JB
authors.lastname: Edel
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: deMello
mesh_terms: D000818:Animals; D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004345:Drug Industry / Q000379:methods; D006801:Humans; D046228:Microarray Analysis / Q000379:methods; D044085:Microfluidics / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*