title: Urinary symptoms and impact on quality of life in women after treatment for endometrial cancer.
abstract: The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment for endometrial cancer. Three validated questionnaires were utilized: the Sandvik Severity Index, the Urinary Distress Inventory-6 (UDI-6), and Incontinence Impact Questionaire-7 (IIQ-7). Our study included 70 women treated for endometrial cancer; 35.7% (25/70) of women reported adjuvant radiation therapy after surgical staging. Urinary incontinence was reported in over 80% of women. Mean UDI-6 and IIQ-7 scores for women treated with adjuvant radiation therapy were higher compared to women with no adjuvant radiation therapy [47(+/-26.8) vs. 35.6(+/-21.7; p = 0.05)] and [24.4(+/-28.5) vs. 8.1(+/-16.4; p = 0.004)], respectively. Treatment with adjuvant radiation therapy was associated with more severe incontinence symptoms and impact on quality of life.
authors.affiliation: Division of Urogynecology and Pelvic Reconstructive Surgery, Alpert Medical School at Brown University, Women and Infants' Hospital of Rhode Island, 695 Eddy St, Ste. 12, Providence, RI 02903, USA. EErekson@wihri.org
authors.forename: E A
authors.initials: EA
authors.lastname: Erekson
authors.forename: V W
authors.initials: VW
authors.lastname: Sung
authors.forename: P A
authors.initials: PA
authors.lastname: DiSilvestro
authors.forename: D L
authors.initials: DL
authors.lastname: Myers
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D016889:Endometrial Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006306:Health Surveys; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life / Q000523:psychology; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000209:etiology* / Q000523:psychology