Polarographic determination of ampicillin in capsules and tablets.
A new polarographic method is used for quantitative analysis of ampicillin dosage forms. The electroactive product is formed by acidic hydrolysis of ampicillin. It gives a well-developed reduction wave with half-wave potential of -0.91 V vs. SCE. The proposed method has good precision. A major advantage is the selectivity, which makes the determination of ampicillin possible without prior separation of the excipient.
Squella
J A
JA
Department of Chemical Pharmacology and Physical Chemistry, Faculty of Chemical and Pharmacological Sciences, University of Chile, Santiago, Chile.
Nunez-Vergara
L J
LJ