title: [Secondary metabolites of a marine mangrove fungus (Penicillium sp. no. 2556) from South China Sea].
abstract: The metabolites of a marine mangrove fungus (Penicillium sp. No. 2556) were studied in this paper and six compounds were isolated from the fermentation liquid. Their structures were elucidated by spectroscopy methods as Sch54796 (1), Sch54794 (2), 4-hydroxybenzoic acid (3), urail (4), succinic acid (5), Vermopyrone (6). Among them, compounds 1, 2 and 6 were firstly isolated from Penicillium sp., Coumpounds 1 and 2 remarkably inhibited the growth of cancer cell lines hep2 and hepG2.
authors.affiliation: Department of Applied Chemistry, College of Sciences, South China Agricultural University, Guangzhou 510642, China. chunyuanli@scau.edu.cn
authors.forename: Chun-Yuan
authors.initials: CY
authors.lastname: Li
authors.forename: Wei-Jia
authors.initials: WJ
authors.lastname: Ding
authors.forename: Chang-Lun
authors.initials: CL
authors.lastname: Shao
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: She
authors.forename: Yong-Cheng
authors.initials: YC
authors.lastname: Lin
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D045744:Cell Line, Tumor; D002681:China; D047169:Cyclotides / Q000737:chemistry / Q000302:isolation & purification*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010226:Parabens / Q000737:chemistry / Q000302:isolation & purification*; D010407:Penicillium / Q000737:chemistry* / Q000378:metabolism; D043982:Rhizophoraceae / Q000382:microbiology*; D017550:Spectroscopy, Fourier Transform Infrared; D019802:Succinic Acid / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000970:Antineoplastic Agents; D047169:Cyclotides; D010226:Parabens; D019802:Succinic Acid; C038193:4-hydroxybenzoic acid