HPLC determination of niridazole.
A high-performance liquid chromatographic method has been developed for the determination of niridazole in bulk form and in pharmaceutical dosage form. A reversed-phase system, based on an octadecylsilane-bonded stationary phase and a 60:40 v/v methanol/water mobile phase, is used. The detector response at 370 nm is linearly related to the amount injected, over a wide range. The method is sensitive, simple, rapid and precise.
El-Rabbat
N A
NA
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Farag
H H
HH
El-Kommos
M E
ME
Refaat
I H
IH