Lisinopril and lisinopril/hydrochlorothiazide preparations on the Belgian market: a comparative study.
Preparations containing lisinopril and the combination lisinopril/hydrochlorothiazide, and formulated as tablets were evaluated with different tests, including in vitro dissolution, assay and content uniformity, and determination of related compounds. The analytical methods were previously validated according to international guidelines. All examined products complied with the postulated requirements.
De Braekeleer
K
K
Service de Contrôle des Médicaments APB, Bruxelles.
Corthout
J
J
D000959:Antihypertensive Agents / Q000032:analysis / Q000592:standards*; D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D005060:Europe; D006852:Hydrochlorothiazide / Q000032:analysis / Q000592:standards*; D017706:Lisinopril / Q000032:analysis / Q000592:standards*; D015203:Reproducibility of Results; D013607:Tablets
D000959:Antihypertensive Agents; D004338:Drug Combinations; D013607:Tablets; D006852:Hydrochlorothiazide; D017706:Lisinopril