[Safety of low dose unfractionated heparin (LDUH) in patients undergoing hip fracture operation].
BACKGROUND
Japanese guideline for prevention of venous thromboemobolism recommends to use LDUH in high-risk patients. Femoral neck fracture belongs to high-risk group. However, use of LUDH has possibilities of causing a fresh hemorrhage from the fracture part and spinal hematoma due to spinal anesthesia. We investigated safety of LDUH in patients for hemiarthroplasty.


METHODS
We compared group receiving LDUH (Group H) with group receiving nothing (Group N) and examined changes of hemoglobin concentrations, amount of perioperative hemorrhage and complications (e.g. spinal hematoma, massive surgical hemorrhage and thrombocytopenia).


RESULTS
No significant differences were seen in two groups and no major complications occurred, except for occurrence of pulmonary embolism in Group N.


CONCLUSIONS
We suggest that using LDUH in hip fracture surgery is safe.
Arimune
Mutsuaki
M
Department of Anesthesiology, Meijibashi Hospital, Matsubara 580-0045.
Morita
Hiroshi
H
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005265:Femoral Neck Fractures / Q000150:complications / Q000601:surgery*; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D012306:Risk; D012449:Safety; D054556:Venous Thromboembolism / Q000209:etiology / Q000517:prevention & control*
D006493:Heparin