title: Optical imaging instrument for muscle oxygenation based on spatially resolved spectroscopy.
abstract: An imaging instrument based on spatially resolved spectroscopy that enables temporal and spatial analyses of muscle oxygenation was designed. The instrument is portable and can be connected to 32 compact and separate-type optical probes. Its measurement accuracy of O(2) saturation and hemoglobin concentration was evaluated using a tissue-equivalent phantom. Imaging and multi-point measurements of tissue oxygen saturation (S(t)O(2)) in the quadriceps muscle were also performed, and dynamic changes in S(t)O(2) in response to increase in exercise intensity (within the rectus femoris region) and variation in exercise protocol (among the rectus femoris, vastus lateralis and vastus medialis) were clearly shown.
authors.affiliation: Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan. kek@bme.ist.hokudai.ac.jp
authors.forename: Khai Jun
authors.initials: KJ
authors.lastname: Kek
authors.forename: Ryuta
authors.initials: R
authors.lastname: Kibe
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Niwayama
authors.forename: Nobuki
authors.initials: N
authors.lastname: Kudo
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000042:Absorption; D000328:Adult; D006801:Humans; D008297:Male; D009132:Muscles / Q000502:physiology*; D055095:Optics and Photonics / Q000295:instrumentation*; D010100:Oxygen / Q000502:physiology*; D019047:Phantoms, Imaging; D013057:Spectrum Analysis
chemical_list: D010100:Oxygen