title: Surface-enhanced stereoselectivity in Mukaiyama aldol reactions catalyzed by clay-supported bis(oxazoline)-copper complexes.
abstract: Surface effects on a laponite-exchanged bis(oxazoline)-copper complex modify the stereochemical course of the Mukaiyama aldol reaction between 2-(trimethylsilyloxy)furan and alpha-ketoesters, leading up to 90% ee (dr 86 : 14) becoming the best overall result obtained for this reaction and significantly improving the homogeneous process.
authors.affiliation: Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón and Instituto Universitario de Catálisis Homogénea, Universidad de Zaragoza-C.S.I.C., Zaragoza, Spain.
authors.forename: María J
authors.initials: MJ
authors.lastname: Fabra
authors.forename: José M
authors.initials: JM
authors.lastname: Fraile
authors.forename: Clara I
authors.initials: CI
authors.lastname: Herrerías
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Lahoz
authors.forename: José A
authors.initials: JA
authors.lastname: Mayoral
authors.forename: Ignacio
authors.initials: I
authors.lastname: Pérez
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000538:Aluminum Silicates / Q000737:chemistry*; D002384:Catalysis; D000077215:Clay; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D007659:Ketones / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D017640:Silicates / Q000737:chemistry*; D013237:Stereoisomerism; D013499:Surface Properties
chemical_list: D000438:Alcohols; D000538:Aluminum Silicates; D007659:Ketones; D009942:Organometallic Compounds; D010080:Oxazoles; D017640:Silicates; D003300:Copper; C524813:laponite; D000077215:Clay