title: Total synthesis of bulbophylol-B.
abstract: The first total synthesis of bulbophylol-B (1) has been achieved with the longest linear sequence of 12 steps and an overall yield of 17.9% via a new and practical approach to construct the dihydrodibenz[b,f]oxepin skeleton employing Wittig, selective reduction, and intramolecular Ullmann reactions as key steps.
authors.affiliation: School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
authors.forename: Jinshun
authors.initials: J
authors.lastname: Lin
authors.forename: Weige
authors.initials: W
authors.lastname: Zhang
authors.forename: Nan
authors.initials: N
authors.lastname: Jiang
authors.forename: Zeyu
authors.initials: Z
authors.lastname: Niu
authors.forename: Kai
authors.initials: K
authors.lastname: Bao
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.forename: Dailin
authors.initials: D
authors.lastname: Liu
authors.forename: Chao
authors.initials: C
authors.lastname: Pan
authors.forename: Xinsheng
authors.initials: X
authors.lastname: Yao
mesh_terms: D001584:Benzoxepins / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001584:Benzoxepins; C568003:bulbophylol-B