title: [Advantages of fixed combinations].
abstract: Fixed combinations are indicated in the treatment of glaucoma and ocular hypertension when monotherapy does not sufficiently reduce IOP. Fixed combinations show better efficacy than the instillation of each separate component and are at least equivalent to the administration of both components in a separate association. They simplify treatment, increase compliance and quality of life, and decrease exposure to preservatives. Although they are less aggressive for patients when a new drug needs to be added, the use of fixed combinations should not decrease the follow-up.
authors.affiliation: Institut du Glaucome, Fondation Hôpital Saint-Joseph, 185, rue Raymond-Losserand, 75674 Paris cedex 14, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Lachkar
mesh_terms: D004359:Drug Therapy, Combination; D064420:Drug-Related Side Effects and Adverse Reactions; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans