title: Surface-functionalized silica-coated gold nanoparticles and their bioapplications.
abstract: Monodisperse Au at SiO(2) nanoparticles has been functionalized with carboxylic groups for further bioconjugation with amino-terminated oligonucleotides. The oligonucleotide-modified Au at SiO(2) nanoprobes have been applied in the fast colorimetric DNA based on the sequence-specific hybridization properties of DNA. Self-assembling behavior of Au at SiO(2) nanoparticles was also investigated.
authors.affiliation: Institute of Materials Research & Engineering and Division of Bioengineering, 3 Research Link, Singapore 117602, Singapore.
authors.forename: Shuhua
authors.initials: S
authors.lastname: Liu
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Zhang
authors.forename: Yubo
authors.initials: Y
authors.lastname: Wang
authors.forename: Fuke
authors.initials: F
authors.lastname: Wang
authors.forename: Ming-Yong
authors.initials: MY
authors.lastname: Han