title: Chlamydia trachomatis serovar distribution and other concurrent sexually transmitted infections in heterosexual men with urethritis in Italy.
abstract: The distribution of Chlamydia trachomatis serovars among 157 heterosexual male patients with urethritis and the presence of coinfections with other sexually transmitted infections were studied. One hundred seventeen (74.5%) patients, with a mean age of 33.7 years, were Italians, whereas 40 (25.5%) were immigrants coming from eastern European countries, Africa, and South America. All the immigrants and 82 (70.0%) Italian patients reported sex with prostitutes. Out of 157 patients, 73 (46.5%) were found positive for C. trachomatis in urethral secretions and eight different C. trachomatis serovars were identified. The most common serovars were E (n = 18; 24.7%), D (n = 15; 20.5%), G (n = 14;19.2%), and F (n = 12; 16.4%). The sequencing data showed a high degree of conservation of the omp1 gene. Thirty-six (46.7%) out of the 73 C. trachomatis-positive patients were coinfected with another sexually transmitted infection. The most common coinfection was gonorrhoea detected in 22 (30.1%) patients, followed by condyloma in eight (8.2%) patients, syphilis in five (6.8%), and HIV in three (4.1%).
authors.affiliation: DESOS, Policlinico S.Orsola, University of Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Donati
authors.forename: A
authors.initials: A
authors.lastname: Di Francesco
authors.forename: A
authors.initials: A
authors.lastname: D'Antuono
authors.forename: S
authors.initials: S
authors.lastname: Pignanelli
authors.forename: A
authors.initials: A
authors.lastname: Shurdhi
authors.forename: A
authors.initials: A
authors.lastname: Moroni
authors.forename: R
authors.initials: R
authors.lastname: Baldelli
authors.forename: R
authors.initials: R
authors.lastname: Cevenini
mesh_terms: D000293:Adolescent; D000328:Adult; D015373:Bacterial Typing Techniques; D002692:Chlamydia trachomatis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D015897:Comorbidity; D017124:Conserved Sequence; D054242:Emigrants and Immigrants; D005061:Europe, Eastern; D006069:Gonorrhea / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology; D020010:Heterosexuality; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000453:epidemiology; D018272:Porins / Q000235:genetics; D015995:Prevalence; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D012703:Serotyping; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology*; D014526:Urethritis / Q000382:microbiology*; D055815:Young Adult
chemical_list: D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis