title: Gypsy endogenous retrovirus maintains potential infectivity in several species of Drosophilids.
abstract: BACKGROUND
  Sequences homologous to the gypsy retroelement from Drosophila melanogaster are widely distributed among drosophilids. The structure of gypsy includes an open reading frame resembling the retroviral gene env, which is responsible for the infectious properties of retroviruses.
  
  
  RESULTS
  In this study we report molecular and phylogeny analysis of the complete env gene from ten species of the obscura group of the genus Drosophila and one species from the genus Scaptomyza.
  
  
  CONCLUSIONS
  The results indicate that in most cases env sequences could produce a functional Env protein and therefore maintain the infectious capability of gypsy in these species.
authors.affiliation: Departament de Genètica, Universitat de València, 46100-Burjassot, Valencia, Spain. jovillo@uv.es
authors.forename: Jose V
authors.initials: JV
authors.lastname: Llorens
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: Clark
authors.forename: Isabel
authors.initials: I
authors.lastname: Martínez-Garay
authors.forename: Sirena
authors.initials: S
authors.lastname: Soriano
authors.forename: Rosa
authors.initials: R
authors.lastname: de Frutos
authors.forename: María J
authors.initials: MJ
authors.lastname: Martínez-Sebastián
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D018428:Drosophilidae / Q000235:genetics* / Q000821:virology; D020077:Endogenous Retroviruses / Q000235:genetics*; D019143:Evolution, Molecular; D017344:Genes, Insect; D015752:Genes, env; D049750:Genome, Insect; D016013:Likelihood Functions; D008957:Models, Genetic; D016366:Open Reading Frames; D010802:Phylogeny; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics; D018626:Retroelements; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014759:Viral Envelope Proteins / Q000235:genetics
chemical_list: D012333:RNA, Messenger; D018626:Retroelements; D014759:Viral Envelope Proteins; D004247:DNA