Novel human rhinoviruses and exacerbation of asthma in children.
To determine links between human rhinoviruses (HRV) and asthma, we used data from a case-control study, March 2003-February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.
Khetsuriani
Nino
N
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Lu
Xiaoyan
X
Teague
W Gerald
WG
Kazerouni
Neely
N
Anderson
Larry J
LJ
Erdman
Dean D
DD
D000293:Adolescent; D001249:Asthma / Q000453:epidemiology / Q000473:pathology* / Q000821:virology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005845:Georgia; D006801:Humans; D010802:Phylogeny; D010850:Picornaviridae Infections / Q000150:complications*; D012229:Rhinovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D014505:Urban Population; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins; C074995:viral protein 1, rhinovirus