[Cardiovascular disorders and depression: a review of epidemiological and possible etiological data].
Depression is a common comorbid condition in patients with cardiovascular diseases (CVD) and a well-known risk factor for the development of CVD and CV mortality too. Depression and CVD are prevalent public health problems in the Western world. The background mechanisms underlying the relationship between depression and CVD are not well clarified. In this article, we review the recent knowledge regarding epidemiological data and possible etiological mechanisms (ie. higher prevalence of smoking, hypertension, metabolic syndrome, obesity in depression or the platelet hyperactivity theory and the endothelial progenitor cell theory) in point of the comorbidity of CVD and mood disorders.
Péter
László
L
Allami Egészségügyi Központ, Pszichiátriai Osztály, Budapest. lacipe@freemail.hu
Döme
Péter
P
Rihmer
Zoltán
Z
Kovács
Gábor
G
Faludi
Gábor
G
D000928:Antidepressive Agents / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology / Q000523:psychology*; D003863:Depression / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D003866:Depressive Disorder / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D048909:Diabetes Complications / Q000453:epidemiology; D042783:Endothelial Cells / Q000187:drug effects; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D013234:Stem Cells / Q000187:drug effects
D000928:Antidepressive Agents