An extractive spectrophotometric method for the determination of tetramisole hydrochloride in pharmaceutical preparations.
A simple extractive photometric method for the determination of tetramisole hydrochloride in pharmaceutical preparations is described. The method uses the formation of coloured complexes of the drug with reagents such as Solochrome Dark Blue, Solochrome Black T, Bromocresol Purple, Bromothymol Blue, Bromophenol Blue and Bromocresol Green in an acidic buffer. The ion-pair complexes formed are quantitatively extracted into chloroform under the experimental conditions.
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Department of Chemistry, Ramnarain Ruia College, Matunga, Bombay 400019, India.
Sapre
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Nayak
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VG