A comparison of pulsed amperometric detection and conductivity detection of underivatized amino-acids in liquid chromatography.
Pulsed amperometric detection (PAD) in tandem with conductivity detection (CD) has been applied to the direct detection of amino-acids by liquid chromatography. Although sensitive, PAD has a limited linear range of response. Sequential use of conductimetric detection and then PAD extends the dynamic range of amino-acid determination.
Welch
L E
LE
Department of Chemistry, Knox College, Galesburg, IL 61401-4999, U.S.A.
Lacourse
W R
WR
Mead
D A
DA
Johnson
D C
DC