title: A giant upper eyelid ossifying pilomatrixoma.
abstract: Pilomatrixoma of the eyelid is extremely rare in middle age and rarely develops into a large tumor. A 45-year-old female developed a painless, progressive swelling (3.0 cm x 2.0 cm) of the left upper eyelid over a period of two years. Overlying skin was normal in color and texture. A differential diagnosis of dermoid, epidermoid cyst, chalazion and basal cell carcinoma was made. An excisional biopsy was performed. A diagnosis of pilomatrixoma was made on histopathological features (dystrophic calcification of matrix with keratin and foreign body granulomatous reaction, basaloid cells and shadow cells/ghost cells). It also comprises ossification apart from the usual calcification. This is a report of an unusually large ossifying pilomatrixoma in left upper eyelid of a middle-aged woman. The patient should be followed up at regular intervals to rule out any recurrence or malignant transformation.
authors.affiliation: Institute of Ophthalmology, Jawaharlal Nehru Medical College, AMU, Aligarh, UP, India. draliraza12@hotmail.com
authors.forename: Syed Ar
authors.initials: SA
authors.lastname: Rizvi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Naim
authors.forename: Mohammad S
authors.initials: MS
authors.lastname: Alam
mesh_terms: D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006201:Hair Diseases / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000473:pathology* / Q000601:surgery; D018296:Pilomatrixoma / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery