title: Interactive two-dimensional fresh blood imaging: a feasibility study.
abstract: This paper presents work on interactive 2D projection magnetic resonance angiography, based on fresh blood imaging (FBI), which integrates navigation and triggering optimisation into a continuous fluoroscopic procedure. The technique was developed on a clinical 1.5-T MRI system and performed in five healthy volunteers. Initial feasibility study compared FBI projection angiograms with maximum intensity projection reformats from multi-slice, ECG-gated, 2D time-of-flight (TOF) in the lower peripheral arteries. A technical performance evaluation of 40 vessel segments showed that FBI generated angiograms of comparable diagnostic quality (P < 0.074) with fewer artefacts (P < 0.003). Quantitative vessel-to-background contrast measurements were higher in FBI (P < 0.014). The technique has potential application as an interactive vascular imaging tool in interventional or multi-location MRI examinations.
authors.affiliation: Department of Radiology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. pauline.wong@cantab.net
authors.forename: Pauline
authors.initials: P
authors.lastname: Wong
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Graves
authors.forename: David J
authors.initials: DJ
authors.lastname: Lomas
mesh_terms: D000792:Angiography / Q000379:methods; D001158:Arteries / Q000473:pathology; D003287:Contrast Media / Q000494:pharmacology; D003952:Diagnostic Imaging / Q000379:methods*; D004562:Electrocardiography / Q000379:methods; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D018810:Magnetic Resonance Angiography / Q000379:methods*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000473:pathology; D015203:Reproducibility of Results
chemical_list: D003287:Contrast Media