title: Effect of preload on left ventricular longitudinal strain by 2D speckle tracking.
abstract: BACKGROUND
  Peak systolic longitudinal strain (PSLS) obtained using the 2D speckle tracking method is a novel indicator of the long-axis function of the left ventricle (LV). We used the 2D strain profile to examine the effect of preload reduction by hemodialysis (HD) on LV PSLS in patients with end-stage renal disease (ESRD).
  
  
  RESULTS
  Twenty-nine pairs of echocardiographic evaluations were obtained before and after dialysis. Global LV PSLS was -18.4 +/- 2.9%, at baseline and decreased to -16.9 +/- 3.2% after HD (P < 0.001). Segmental analysis showed that the decrease in PSLS after dialysis was most prominent in mid-LV segments (-17.1 +/- 3.5% vs. -15.4 +/- 3.4%, P < 0.001).
  
  
  CONCLUSIONS
  PSLS obtained from the 2D strain profile is a reliable parameter that may be useful for evaluating LV systolic long-axis function. However, PSLS should be applied cautiously in ESRD patients because it could be affected by dialysis.
authors.affiliation: Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyukwan University School of Medicine, Seoul, Korea.
authors.forename: Jin-Oh
authors.initials: JO
authors.lastname: Choi
authors.forename: Dae-Hee
authors.initials: DH
authors.lastname: Shin
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Cho
authors.forename: Young Bin
authors.initials: YB
authors.lastname: Song
authors.forename: Jun Hyung
authors.initials: JH
authors.lastname: Kim
authors.forename: Yoon Goo
authors.initials: YG
authors.lastname: Kim
authors.forename: Sang-Chol
authors.initials: SC
authors.lastname: Lee
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Park
mesh_terms: D000465:Algorithms; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology*