title: Electrocatalytic oxidation of L-tyrosine by a nitroxide.
abstract: The electrochemistry of L-tyrosine was studied by cyclic voltammetry at a glassy carbon electrode. Although L-tyrosine itself showed very poor electrochemical response, the response could be greatly enhanced by using 4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxy (HO-TEMPO) as a mediator that enables a sensitive determination of the substrate. An electrocatalytic EC' mechanism with the oxoammonium ion of HO-TEMPO as the active oxidant is proposed. The catalytic rate constant was determined to be 2.0 x 10(4) M(-1) s(-1) by using chronoamperometry.
authors.affiliation: Department of Physics, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu, People's Republic of China.
authors.forename: X L
authors.initials: XL
authors.lastname: Wen
authors.forename: Y
authors.initials: Y
authors.lastname: Jia
authors.forename: L
authors.initials: L
authors.lastname: Yang
authors.forename: Z L
authors.initials: ZL
authors.lastname: Liu