title: SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap.
abstract: CONCLUSIONS
  The interpretation of genome-wide association results is confounded by linkage disequilibrium between nearby alleles. We have developed a flexible bioinformatics query tool for single-nucleotide polymorphisms (SNPs) to identify and to annotate nearby SNPs in linkage disequilibrium (proxies) based on HapMap. By offering functionality to generate graphical plots for these data, the SNAP server will facilitate interpretation and comparison of genome-wide association study results, and the design of fine-mapping experiments (by delineating genomic regions harboring associated variants and their proxies).
  
  
  BACKGROUND
  SNAP server is available at http://www.broad.mit.edu/mpg/snap/.
authors.affiliation: The Framingham Heart Study of the National Heart, Lung, and Blood Institute of the National Institutes of Health, USA.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Johnson
authors.forename: Robert E
authors.initials: RE
authors.lastname: Handsaker
authors.forename: Sara L
authors.initials: SL
authors.lastname: Pulit
authors.forename: Marcia M
authors.initials: MM
authors.lastname: Nizzari
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: O'Donnell
authors.forename: Paul I W
authors.initials: PI
authors.lastname: de Bakker
mesh_terms: D015894:Genome, Human; D055106:Genome-Wide Association Study; D005838:Genotype; D006801:Humans; D020407:Internet; D015810:Linkage Disequilibrium; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012984:Software