title: Coordination properties of cefadroxil antibiotic: synthesis and equilibrium studies of the binary and ternary complexes involving amino acids and DNA units.
abstract: The formation equilibria for the binary complexes of Cu(II), Ni(II), Co(II), Zn(II), Mn(II), Hg(II), Cd(II), Ca(II), and Mg(II) with cefadroxil (Cef) and for the ternary complexes Cu(Cef)(L), where L refers to amino acid or DNA, were investigated. The protonation constants of cefadroxil and formation constants of the formed complexes were determined at 25 degrees C and mu = 0.1 M NaNo(3). Cooper(II) and cobalt(II) complexes of cefadroxil were isolated in solid state and characterized by elemental analysis, infrared and electronic spectral, conductivity and magnetic measurement.
authors.affiliation: Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt.
authors.forename: M M
authors.initials: MM
authors.lastname: Shoukry
authors.forename: W M
authors.initials: WM
authors.lastname: Hosny
authors.forename: A A
authors.initials: AA
authors.lastname: Razik
authors.forename: R A
authors.initials: RA
authors.lastname: Mohamed