title: Quantitative non-destructive determination of salicylic acid acetate in aspirin tablets by Raman spectroscopy.
abstract: Laser Raman spectroscopy was used for the quantitative determination of aspirin in aspirin-maize starch tablets. A calibration curve was constructed from spectra obtained from tablets with known quantities of aspirin and starch. The calibration curve is given from the relationship: I(552)/I(478) = (W(aspirin)/W(starch)) x 4.21, where I(552) and I(478) are the relative Raman intensities for the 552 and 478 cm(-1) Raman shift, respectively. W(aspirin) and W(starch) represent the weight of aspirin and starch in a pellet.
authors.affiliation: Institute of Chemical Engineering and High Temperature Chemical Processes, and Department of Pharmacy, University of Patras, Patras, Greece.
authors.forename: C G
authors.initials: CG
authors.lastname: Kontoyannis
authors.forename: M
authors.initials: M
authors.lastname: Orkoula