title: Determination of bromine in organic compounds by high-performance liquid chromatography.
abstract: A method is proposed for the determination of bromine in organic compounds (which may also contain chlorine and iodine) by oxygen-flask combustion of the compound followed by pre-column reaction of bromide with acetanilide and 2-iodosobenzoic acid to form 4-bromoacetanilide which is then chromatographed on an ODS column with a mobile phase of methanol: water, 65:35 v/v, detection at 240 nm, and 4-N-acetylaminotoluene as internal standard. The method is rapid and precise (RSD </= 1%), and applicable to a variety of bromine-containing organic compounds; the limit of detection is 0.2 ng of bromine.
authors.affiliation: Department of Chemistry, Rani Durgavati University, Jabalpur 482001, Madhya Pradesh, India.
authors.forename: A
authors.initials: A
authors.lastname: Jain
authors.forename: A
authors.initials: A
authors.lastname: Verma
authors.forename: K K
authors.initials: KK
authors.lastname: Verma