title: Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature.
abstract: Adrenal cystic lesions are uncommon and we analyzed clinical and pathologic features of 25 such cases from a single institute over 23 years. There were 16 pseudocysts, eight endothelial cysts, and one epithelial cyst. Seven of eight endothelial cysts were confirmed to be lymphangiomatous by D2-40 immunostaining. We suggest that pseudocysts and endothelial cysts may have different histogenesis. The proposed mesothelial origin of adrenal epithelial cyst cannot be confirmed in our example. Seven adrenal pseudocysts were associated with tumor, including two pheochromocytomas, one neuroblastoma, one adrenal cortical carcinoma, one adrenal cortical adenoma, one myelolipoma, and one schwannoma. The distinction of true cystic lesion from cystic neoplasm is important and requires thorough sampling of the specimens.
authors.affiliation: Department of Pathology, Chang Gung Memorial Hospital, No. 5 Fu-Shin Street, Kuei-Shan, Taoyuan, Taiwan, Republic of China.
authors.forename: Hui-Ping
authors.initials: HP
authors.lastname: Chien
authors.forename: Yu-Sun
authors.initials: YS
authors.lastname: Chang
authors.forename: Pei-Sung
authors.initials: PS
authors.lastname: Hsu
authors.forename: Jen-Der
authors.initials: JD
authors.lastname: Lin
authors.forename: Yi-Chin
authors.initials: YC
authors.lastname: Wu
authors.forename: Hui-Lang
authors.initials: HL
authors.lastname: Chang
authors.forename: Cheng-Keng
authors.initials: CK
authors.lastname: Chuang
authors.forename: Ke-Hung
authors.initials: KH
authors.lastname: Tsuei
authors.forename: Chuen
authors.initials: C
authors.lastname: Hsueh
mesh_terms: D000307:Adrenal Gland Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003560:Cysts / Q000000981:diagnostic imaging / Q000473:pathology*; D004727:Endothelium / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed