title: Perforated appendicitis presenting with ileo-caecal ulceration and mechanical intestinal obstruction.
abstract: A 30-year-old lady presented with a 6-month history of recurrent partial intestinal obstruction associated with intermittent fever, anorexia and weight loss. Barium meal follow-through and colonoscopic evaluation suggested ulceration of the ileum and caecum with small bowel obstruction. Histology of the lesions showed marked acute and chronic inflammation consistent with ulceration and granulation tissue. Abdominal CT revealed circumferential thickening of the ascending colon, caecum and terminal ileum with extraluminal air pockets. Surgical exploration revealed a large conglomerate mass involving the terminal ileum, caecum and ascending colon. Histopathology of the resected specimen revealed perforated appendix with nonspecific ulceration of the surrounding bowel. She recovered completely after surgery and did not suffer from gastrointestinal symptoms in the 14 months of follow-up.
authors.affiliation: Department of Gastroenterology, Calicut Medical College & PVS Hospital Kozhikode, Kerala, India.
authors.forename: H
authors.initials: H
authors.lastname: Kareem
authors.forename: S
authors.initials: S
authors.lastname: Sebastian
authors.forename: T
authors.initials: T
authors.lastname: Jose
authors.forename: V
authors.initials: V
authors.lastname: Thomas
mesh_terms: D000328:Adult; D001064:Appendicitis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007079:Ileitis / Q000209:etiology* / Q000473:pathology; D007415:Intestinal Obstruction / Q000209:etiology*; D053706:Typhlitis / Q000209:etiology* / Q000473:pathology