Oxidation of thiols by sodium N-haloarylsulphonamides.
The methods for direct titration of thiols with N-haloarylsulphonamides have been evaluated by studying the oxidation of 2-mercaptobenzoic acid, 2-mercaptopropionic acid, 3-mercaptopropionic acid, 2-naphthyl mercaptan, 2-mercaptoethanol, mercaptosuccinic acid, thiophenol, p-chlorothiophenol, butyl mercaptan and monothioglycerol, with chloramine-T (CAT), bromamine-T (BAT) and bromamine-B (BAB). The optimum conditions have been established. The precision was found to be poorer for titrations with CAT. BAB was found to give better precision and accuracy for the determination of all ten thiols studied, and is recommended for use.
Murthy
A S
AS
Department of Post-graduate Studies and Research in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, India.
Murthy
S A
SA
Mahadevappa
D S
DS