title: Study of an actinomycin complex by mass spectrometry-mass spectrometry.
abstract: The characterization of components within actinomycin complexes may often be complicated by the lack of material and standards of known actinomycins. Mass spectrometry-mass spectrometry can be employed both as a separatory device and as a means of structural analysis. This technique has been applied to an actinomycin complex obtained from a previously unidentified Streptomyces strain. The method involved initial work on a known material, in this case actinomycin D, and application to the unknown material. Three major components within the unknown complex were characterized as actinomycins D, F(8), and F(9).
authors.affiliation: Department of Chemistry, UMIST, Manchester, England.
authors.forename: M
authors.initials: M
authors.lastname: Barber
authors.forename: D
authors.initials: D
authors.lastname: Bell
authors.forename: M
authors.initials: M
authors.lastname: Morris
authors.forename: L
authors.initials: L
authors.lastname: Tetler
authors.forename: M
authors.initials: M
authors.lastname: Woods
authors.forename: B W
authors.initials: BW
authors.lastname: Bycroft
authors.forename: J J
authors.initials: JJ
authors.lastname: Monaghan
authors.forename: W E
authors.initials: WE
authors.lastname: Morden
authors.forename: B N
authors.initials: BN
authors.lastname: Green