Prevention, diagnosis, and treatment of cerebral palsy in near-term and term infants.
The incidence, risk factors, and etiology of cerebral palsy (CP) are reviewed based on evidence-based data. Current methods for diagnosing risk for brain injury, including neuroimaging data on CP in this group of infants are presented. Prevention of CP in term and near-term infants currently seems to be promising with neuroprotection with hypothermia for neonatal encephalopathy secondary to presumed acute hypoxic-ischemia at birth. Treatment of CP based on evidenced-based data will be reviewed.
Shankaran
Seetha
S
Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. sshankar@med.wayne.edu
D001921:Brain / Q000473:pathology; D002547:Cerebral Palsy / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D020925:Hypoxia-Ischemia, Brain / Q000150:complications; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009460:Neurologic Examination; D012307:Risk Factors; D012720:Severity of Illness Index