title: Mediastinal lymphoma with complete atrioventricular block in a horse.
abstract: A 15-year-old, neutered-male pony presented with a history of weight loss during 4 months. Clinical evaluation revealed severe bradycardia and complete atrioventricular block. At necropsy, a lobulated mass in the anterior mediastinum and moderate enlargement of the superficial cervical lymph nodes were observed. The vagus nerve and the brachiocephalic trunk were embedded in this anterior mediastinal tumor. Histologically, the mass was composed of sheets of neoplastic lymphoid cells expressing CD3, with a low mitotic rate. To the best of our knowledge, this is the first reported case of mediastinal lymphoma associated with complete atrioventricular block in horses.
authors.affiliation: Department of Veterinary Laboratory Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan. sugiyama@muses.tottori-u.ac.jp
authors.forename: Akihiko
authors.initials: A
authors.lastname: Sugiyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Takeuchi
authors.forename: Takehito
authors.initials: T
authors.lastname: Morita
authors.forename: Aya
authors.initials: A
authors.lastname: Matsuu
authors.forename: Teppei
authors.initials: T
authors.lastname: Kanda
authors.forename: Akinori
authors.initials: A
authors.lastname: Shimada
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Amaya
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Hikasa
mesh_terms: D000818:Animals; D004452:Echocardiography / Q000662:veterinary; D004562:Electrocardiography / Q000662:veterinary; D017809:Fatal Outcome; D006327:Heart Block / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D006651:Histocytochemistry / Q000662:veterinary; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D008223:Lymphoma / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*