Reliable and facile method for preparation of solventless bilayer lipid membranes for electroanalytical investigations.
Bilayer lipid membranes continue to be of interest as elements for development and investigation of chemically-modified electrodes and biosensors, yet also continue to be difficult to prepare and replicate with precision. A simplified and reliable technique for the rapid formation of solventless bilayer lipid membranes is described, and the method has been shown to produce membranes which nominally vary by only 5-10% with respect to ion conductivity. Methods for rapid physical and chemical characterization of these membranes for establishment of reproducibility and quality are given.
Nikolelis
D P
DP
Chemical Sensors Group, Department of Chemistry, Erindale Campus, University of Toronto, 3359 Mississauga Road North, Mississauga, Ontario, Canada LSL 1C6.
Krull
U J
UJ