Studies on the formation of Cu(II) and Ni(II) complexes of l,2-dihydroxy-9,10-anthraquinone and lack of stimulated superoxide formation by the complexes.
Formation of Cu(II) and Ni(II) complexes of 1,2,-dihydroxy-9,10-anthraquinone (DHA) has been studied by the spectrophotometric method. Both the metals form stable complexes of the type [M(LH)(3)](-) where LHH(1) represents DHA. The effective stability constant of the Cu(II) complex is 5.135 x 10(29) while that of the Ni(II) complex is 3.446 x 10(25). These complexes, unlike free DHA, do not catalyze the flow of electrons from NADH to molecular O(2) through NADH dehydrogenase.
Das
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Saha
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Mandal
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PC