title: Body size and breast cancer in a black population--the Barbados National Cancer Study.
abstract: OBJECTIVE
  To evaluate the relationship between body size and incident breast cancer in an African-origin Caribbean population.
  
  
  METHODS
  This investigation is based on 222 incident breast cancer cases and 454 controls from the Barbados National Cancer Study (BNCS) in whom body size variables that included height, weight, body-mass index (BMI), waist and hip circumferences (WC, HC), and waist-hip ratio (WHR) were compared. Multivariate-adjusted logistic regression analyses were performed and the findings are presented as odds ratios (ORs) with 95% confidence intervals (CI).
  
  
  RESULTS
  Although 33% of cases and 39% of controls were obese (BMI > or = 30 kg/m(2)), BMI was not found to be a significant predictor of breast cancer in the multivariate analyses. Tall stature increased risk among women > or =50 years (OR = 2.16, 95% CI (1.02, 4.58)), and a dual effect with age was suggested for both WC and WHR (decreased risk for those aged < or =50 years; increased risk among those > or =50 years).
  
  
  CONCLUSIONS
  Body size appears to influence the risk of breast cancer in this population of African origin. The BNCS data suggest that a few, but not all body size factors play a role in breast cancer risk, and that age may affect these relationships.
authors.affiliation: Department of Preventive Medicine, Stony Brook University, Stony Brook, NY 11794-8036, USA. bnemesure@notes.cc.sunysb.edu
authors.forename: Barbara
authors.initials: B
authors.lastname: Nemesure
authors.forename: Suh-Yuh
authors.initials: SY
authors.lastname: Wu
authors.forename: Anselm
authors.initials: A
authors.lastname: Hennis
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Leske
mesh_terms: D001460:Barbados / Q000453:epidemiology; D044383:Black People; D015992:Body Mass Index; D049628:Body Size; D001835:Body Weight; D001943:Breast Neoplasms / Q000453:epidemiology / Q000208:ethnology* / Q000209:etiology* / Q000473:pathology; D016022:Case-Control Studies; D004034:Diet Surveys; D005260:Female; D006801:Humans; D015994:Incidence; D008019:Life Style; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires; D049629:Waist-Hip Ratio / Q000592:standards