A case of IgG4-associated cholangitis and autoimmune pancreatitis responsive to corticosteroids.
BACKGROUND
A 72-year-old male presented to the emergency department with epigastric pain, anorexia and progressive jaundice of 1 week's duration. He had no prior history of gastrointestinal illness, diabetes or cancer. He did not smoke or consume alcohol. He did have a family history of colon and bone cancer.


METHODS
Biochemical and serologic studies, CT scan, abdominal ultrasound, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography, biliary cytology, pancreas needle biopsies and immunohistochemical stainings.


METHODS
Autoimmune pancreatitis with IgG(4)-associated sclerosing cholangitis affecting the extrahepatic biliary ducts and mimicking primary sclerosing cholangitis and cholangiocarcinoma.


RESULTS
Corticosteroids and immunomodulatory therapy.
Small
Aaron J
AJ
Internal Medicine, New York-Presbyterian Hospital/Weill Cornell Medical College, NY, USA.
Loftus
Conor G
CG
Smyrk
Thomas C
TC
Baron
Todd H
TH
D000368:Aged; D001327:Autoimmune Diseases; D018281:Cholangiocarcinoma / Q000175:diagnosis*; D015209:Cholangitis, Sclerosing / Q000188:drug therapy / Q000276:immunology*; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D010195:Pancreatitis / Q000188:drug therapy / Q000276:immunology*; D016896:Treatment Outcome
D005938:Glucocorticoids; D007074:Immunoglobulin G