title: Takotsubo cardiomyopathy with marked ST-segment elevation and electrical alternans complicated with hyperglycemic hyperosmolar state.
abstract: This is the first report of a case of Takotsubo cardiomyopathy with a hyperglycemic hyperosmolar state (HHS). This case presented with marked ST-segment elevation and electrical alternans, uncommon findings in Takotsubo cardiomyopathy. We believe that hyperosmolarity-induced myocardial dehydration and consequent increase in intracellular calcium concentration may be the mechanism of Takotsubo cardiomyopathy and electrical alternans in HHS.
authors.affiliation: Division of Internal Medicine, Saiseikai Kanazawa Hospital, Ishikawa, Japan.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Oe
authors.forename: Kiyoo
authors.initials: K
authors.lastname: Mori
authors.forename: Michio
authors.initials: M
authors.lastname: Otsuji
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Konno
authors.forename: Noboru
authors.initials: N
authors.lastname: Fujino
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamagishi
mesh_terms: D000369:Aged, 80 and over; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D054549:Takotsubo Cardiomyopathy / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*