title: Guggulsterone: a potent farnesoid X receptor antagonist and its rapidly evolving role as a systemic anticarcinogenic agent.
authors.forename: Shailendra
authors.initials: S
authors.lastname: Kapoor
mesh_terms: D016588:Anticarcinogenic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D017209:Apoptosis / Q000187:drug effects; D001471:Barrett Esophagus / Q000188:drug therapy* / Q000473:pathology; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors*; D006801:Humans; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology; D011282:Pregnenediones / Q000494:pharmacology / Q000627:therapeutic use*; D018160:Receptors, Cytoplasmic and Nuclear / Q000037:antagonists & inhibitors*; D050796:STAT3 Transcription Factor / Q000378:metabolism; D014157:Transcription Factors / Q000037:antagonists & inhibitors*; D000099150:Receptor, Farnesoid X-Activated
chemical_list: D016588:Anticarcinogenic Agents; D004268:DNA-Binding Proteins; D011282:Pregnenediones; D018160:Receptors, Cytoplasmic and Nuclear; D050796:STAT3 Transcription Factor; D014157:Transcription Factors; D000099150:Receptor, Farnesoid X-Activated; C494086:STAT3 protein, human; C023617:pregna-4,17-diene-3,16-dione