title: Simultaneous determination of propacetamol and paracetamol by derivative spectrophotometry.
abstract: A first-derivative spectrophotometric method for the simultaneous determination of propacetamol hydrochloride (PRO) and paracetamol (PA) is described. Measurements are made at the zero-crossing wavelengths at 242.0 for PRO and 239.0 nm for PA. The calibration graphs were linear up to 20.0 and 15.0 mg l(-1) of PRO and PA, respectively, the limits of quantification were 0.75 and 0.46 mg l(-1). The possible interfering effects of other substances were studied. The method was applied to determining the stability of PRO in ethanolic solutions and in glucose and saline parenteral solutions.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Rodenas
authors.forename: M S
authors.initials: MS
authors.lastname: García
authors.forename: C
authors.initials: C
authors.lastname: Sánchez-Pedreño
authors.forename: M I
authors.initials: MI
authors.lastname: Albero