Determination of orthoesters by hydrolysis and Karl Fischer titrimetry.
The acid hydrolysis of orthoesters has been made the basis of a titrimetric method. The method involves reaction of an orthoester with a known excess of water in a trichloroacetic acid-methyl alcohol system, followed by determination of unreacted water by Karl Fischer titration.
Clancy
D J
DJ
Research Division, W. R. GRACE & Company, Clarksville, Maryland 21029, U.S.A.
Kramm
D E
DE