Reduction of carbon-carbon double bonds using organocatalytically generated diimide.
An efficient method has been developed for the reduction of carbon-carbon double bonds with diimide, catalytically generated in situ from hydrazine hydrate. The employed catalyst is prepared in one step from riboflavin (vitamin B(2)). Reactions are carried out in air and are a valuable alternative when metal-catalyzed hydrogenations are problematic.
Smit
Christian
C
Stratingh Institute for Chemistry, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Fraaije
Marco W
MW
Minnaard
Adriaan J
AJ
D000447:Aldehydes; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D006834:Hydrazines / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007094:Imides / Q000737:chemistry*; D008956:Models, Chemical; D008968:Molecular Conformation; D015394:Molecular Structure; D012256:Riboflavin / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D000447:Aldehydes; D006834:Hydrazines; D007094:Imides; D012997:Solvents; D002244:Carbon; D006859:Hydrogen; D012256:Riboflavin