Absolute configuration of beta-agarofuran nucleus of euojaponine C by CD exciton chirality method.
A new celastraceae alkaloid, euojaponine C has been isolated from the methanol extract of the root bark ofEuonymus japonica. With the relative stereochemistry of euojaponine C established by NOESY data, the absolute stereochemistry has been determined by circular dichroism (CD) exciton chirality method. The CD of the 2, 5-bis-phenyl benzoate of triacetonide derived from the LiAlH(4) hydrolysate, euonyminol shows that the configuration of C-2 and C-5 are both R.
Ryu
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JH
College of Pharmacy, Sookmyung Wome's University, Chungpa-Dong, Youngsan-Ku, 140-742, Seoul, Korea.
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Han
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Han
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