title: Quantitative treatment of substituent effects in the polarographic investigations of some potential antineoplastic 2-amino-4-aryl-5-phenylazothiazoles.
abstract: Polarographic reduction of 2-amino-4-aryl-5-phenylazothiazoles takes place in a single 2-electron transfer, giving a diffusion-controlled irreversible wave in the pH range 2.0-10.0. Substituents in the 4-position of the thiazole moiety shift the half-wave potential through conjugation of the system. A correlation of E(sol;1 2 ) with the Brown and Hammett substituent constant has also been established.
authors.affiliation: Department of Chemistry, University of Roorkee, Roorkee, India.
authors.forename: W U
authors.initials: WU
authors.lastname: Malik
authors.forename: R N
authors.initials: RN
authors.lastname: Goyal
authors.forename: R
authors.initials: R
authors.lastname: Jain