Mediastinal lymphoma with complete atrioventricular block in a horse.
A 15-year-old, neutered-male pony presented with a history of weight loss during 4 months. Clinical evaluation revealed severe bradycardia and complete atrioventricular block. At necropsy, a lobulated mass in the anterior mediastinum and moderate enlargement of the superficial cervical lymph nodes were observed. The vagus nerve and the brachiocephalic trunk were embedded in this anterior mediastinal tumor. Histologically, the mass was composed of sheets of neoplastic lymphoid cells expressing CD3, with a low mitotic rate. To the best of our knowledge, this is the first reported case of mediastinal lymphoma associated with complete atrioventricular block in horses.
Sugiyama
Akihiko
A
Department of Veterinary Laboratory Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan. sugiyama@muses.tottori-u.ac.jp
Takeuchi
Takashi
T
Morita
Takehito
T
Matsuu
Aya
A
Kanda
Teppei
T
Shimada
Akinori
A
Amaya
Tomohiko
T
Hikasa
Yoshiaki
Y
D000818:Animals; D004452:Echocardiography / Q000662:veterinary; D004562:Electrocardiography / Q000662:veterinary; D017809:Fatal Outcome; D006327:Heart Block / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D006651:Histocytochemistry / Q000662:veterinary; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D008223:Lymphoma / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*