title: Vaccinia virus in humans and cattle in southwest region of Sao Paulo state, Brazil.
abstract: A new outbreak of Vaccinia virus was observed in Southwest region of São Paulo State, Brazil. The disease was observed in four small dairy farms with manual milking. Lesions were detected in cattle and in humans previously vaccinated and not vaccinated against smallpox. Although several reports of Vaccinia virus outbreaks have been occurring in Brazil, it was not yet reported in this region. This outbreak reinforces the viral circulation in our country. The disease in persons previously vaccinated and not vaccinated against smallpox reinforces the absence of immunity, the risk to the human health, and the need for more epidemiologic and immunologic studies.
authors.affiliation: University of São Paulo State, School of Veterinary Medicine, Department of Veterinary Hygiene and Public Health, Botucatu, Brazil. jane@fmvz.unesp.br
authors.forename: Jane
authors.initials: J
authors.lastname: Megid
authors.forename: Camila Michele
authors.initials: CM
authors.lastname: Appolinário
authors.forename: Hélio
authors.initials: H
authors.lastname: Langoni
authors.forename: Edviges Maristela
authors.initials: EM
authors.lastname: Pituco
authors.forename: Liria Hiromi
authors.initials: LH
authors.lastname: Okuda
mesh_terms: D000818:Animals; D001483:Base Sequence; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D002522:Chlorocebus aethiops; D015605:Cowpox / Q000453:epidemiology* / Q000662:veterinary; D003588:Cytopathogenic Effect, Viral; D017931:DNA Primers; D004279:DNA, Viral / Q000235:genetics; D004196:Disease Outbreaks; D006801:Humans; D008854:Microscopy, Electron; D016273:Occupational Exposure; D016133:Polymerase Chain Reaction; D014616:Vaccinia virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity / Q000648:ultrastructure; D014709:Vero Cells
chemical_list: D017931:DNA Primers; D004279:DNA, Viral