title: [Sleep apnea syndrome in patients with cardiac disease].
abstract: We examined the incidence of sleep-apnea syndrome (SAS; 5 or more episodes of apnea/hypopnea in 1 hour) in 213 patients (152 male, 67.8 +/- 10.9 years) with various cardiac diseases by a modified sleep polygraph (morpheus; Teijin Pharma, Tokyo) from July 2005 to April 2007. Mild sleep disturbance was defined as 5< or = AHI<20, moderate sleep disturbance as 20< or = AHI<40, and severe sleep disturbance as 40< or = AHI. SAS was seen in 87.3% of the patients. This high incidence sharply contrasts with 7.5% reported in factory workers in Japan. Body mass index, though significant, was scarcely correlated with the severity of SAS (p<0.01). As sleep disturbance became severe, the proportion of an obstructive, central, and eventually mixed obstructive-central SAS increased. Although the overall severity was not different between different categories of cardiac diseases, obstructive-central SAS was seen far more frequent in congestive heart failure. Hypertension was closely associated with apnea/hypopnea. A tight correlation between SAS and various cardiac diseases was suggested.
authors.affiliation: Clinical Laboratory, Saiseikai Saijyo Hospital, Saijyo 793-0027, Japan. f1225726117@yahoo.co.jp
authors.forename: Kazumi
authors.initials: K
authors.lastname: Fujita
authors.forename: Yuka
authors.initials: Y
authors.lastname: Wada
authors.forename: Takuya
authors.initials: T
authors.lastname: Aono
authors.forename: Gosuke
authors.initials: G
authors.lastname: Sugi
authors.forename: Noriaki
authors.initials: N
authors.lastname: Ohta
authors.forename: Shozo
authors.initials: S
authors.lastname: Sueda
authors.forename: Takahiko
authors.initials: T
authors.lastname: Nomoto
authors.forename: Akira
authors.initials: A
authors.lastname: Oshita
mesh_terms: D000368:Aged; D015992:Body Mass Index; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*