title: Efficacy of bentonite clay in ameliorating aflatoxicosis in piglets fed aflatoxin contaminated diets.
abstract: The efficacy of locally produced bentonite was evaluated with respect to ameliorating the adverse effects of aflatoxins (AF) in piglets fed AF contaminated diets. Forty eight piglets were randomly assigned to one of four treatments: 1) 0 g of bentonite and 0 microg AF/kg feed (control); 2) 4 g of bentonite plus 200 microg AF/kg feed (AF + Bento 4); 3) 5 g of bentonite plus 200 microg AF/kg feed (AF + Bento 5) and 4) 0 g of bentonite plus 200 microg AF/kg feed (AFA). Piglets in the AFA treatment had lower overall average daily weight gain (ADG), feed conversion efficiency, albumin (ALB) and total protein (TP) compared to the control diet, while mean serum leukocyte and enzyme activities (glutamic-oxalacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), gamma glutamyltransferase (GGT), alkaline phosphate (ALP) and lactic dehydrogenase (LDH)) were significant increased. The inclusion of bentonite at 0.4% or 0.5% in the AF contaminated diet restored the lower performance, feed efficiency and abnormal blood profiles of the piglets given AF and no differences between 0.4 and 0.5% inclusion of bentonite. The findings in the present study provide critically needed confirmation that bentonite has the ability to reduce the adverse effects of AF.
authors.affiliation: Department of Animal Nutrition, Nong Lam University, Hochiminh City, Vietnam. qthieu68@yahoo.com
authors.forename: Nguyen Quang
authors.initials: NQ
authors.lastname: Thieu
authors.forename: Brian
authors.initials: B
authors.lastname: Ogle
authors.forename: Hans
authors.initials: H
authors.lastname: Pettersson
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000931:Antidotes / Q000008:administration & dosage*; D001546:Bentonite / Q000008:administration & dosage*; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D005506:Food Contamination; D008297:Male; D015651:Mycotoxicosis / Q000188:drug therapy* / Q000201:enzymology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000188:drug therapy* / Q000201:enzymology; D000096702:Aflatoxin Poisoning
chemical_list: D000931:Antidotes; D001546:Bentonite