Hyperzincemia and hypercalprotectinemia: unsuccessful treatment with tacrolimus.
We report on a 5-year-old boy with hyperzincemia and hypercalprotectinemia. Treatment began with Tacrolimus at the age of 4 years and 6 months. Despite an initial correction of clinical and biological symptoms, zincemia and calprotectinemia progressively worsened with secondary reappearance of symptoms.


CONCLUSIONS
Tacrolimus seems to have a transient effect in the treatment of Hyperzincemia and hyperprolactinemia.
Isidor
B
B
Service de Génétique Médicale, Centre Hospitalo-Universitaire, Nantes, France. bertrand.isidor@chu-nantes.fr
Poignant
S
S
Corradini
N
N
Fouassier
M
M
Quartier
P
P
Roth
J
J
Picherot
G
G
D002675:Child, Preschool; D006801:Humans; D039841:Leukocyte L1 Antigen Complex / Q000097:blood*; D008297:Male; D008659:Metabolic Diseases / Q000097:blood* / Q000188:drug therapy*; D016559:Tacrolimus / Q000627:therapeutic use*; D017211:Treatment Failure; D015032:Zinc / Q000097:blood*
D039841:Leukocyte L1 Antigen Complex; D015032:Zinc; D016559:Tacrolimus