Structure-activity relationships of some 5-nitro-2-furaldehyde oximes and hydrazones.
5-Nitro-2-furaldoxime, 5-nitro-2-furaldehyde hydrazone, and several derivatives have been prepared, and their stereochemistry studied by NMR. The relationship between the structures of the compounds and their in vitro and in vivo antimicrobial activity was investigated.
Howarth
G A
GA
Pharmaceutical Research Laboratory, Geigy (U.K.) Ltd., Trafford Park, Manchester, 17, U.K.
Hoyle
W
W
Wakefield
B J
BJ