Synthesis of methacrylic-ferulic acid copolymer with antioxidant properties by single-step free radical polymerization.
A novel, simple, and cheap method to synthesize antioxidant methacrylic-ferulic acid copolymer (PMAA-FA) by free radical polymerization was developed by employing a hydrogen peroxide-ascorbic acid pair to produce hydroxyl radicals acting as radical initiators. FT-IR spectra were performed to verify the insertion of ferulic acid into the polymeric chain, and the antioxidant activity of PMAA-FA was compared to that of a control polymer synthesized in the absence of antioxidant molecule. Good antioxidant activity was demonstrated by obtained materials, showing the efficiency of the polymerization method. This material could be useful in the pharmaceutical field and in the food industry (food packaging).
Puoci
Francesco
F
Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, CS, Italia. francesco.puoci@unical.it
Iemma
Francesca
F
Curcio
Manuela
M
Parisi
Ortensia I
OI
Cirillo
Giuseppe
G
Spizzirri
Umile G
UG
Picci
Nevio
N
D000975:Antioxidants / Q000138:chemical synthesis* / Q000494:pharmacology; D001205:Ascorbic Acid; D003373:Coumaric Acids / Q000737:chemistry; D006861:Hydrogen Peroxide; D011091:Polyesters / Q000138:chemical synthesis* / Q000494:pharmacology; D011108:Polymers / Q000138:chemical synthesis*; D011109:Polymethacrylic Acids / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
D000975:Antioxidants; D003373:Coumaric Acids; D011091:Polyesters; D011108:Polymers; D011109:Polymethacrylic Acids; C539557:methacrylic-ferulic acid copolymer; C030613:polymethacrylic acid; C004999:ferulic acid; D006861:Hydrogen Peroxide; D001205:Ascorbic Acid