title: [Study on the effect of phloretin on inhibiting malignant pheotype of BEL-7402 cells].
abstract: OBJECTIVE
  To investigate the effect of phloretin on inhibiting BEL-7402 cells' growth, invasive, migration and adhesion ability and the rate of colony formation.
  
  
  METHODS
  BEL-7402 cells' growth, invasive, migration and adhesion ability and the rate of colony formation were examined with MIT method and Costar Transwell.
  
  
  RESULTS
  Phloretin inhibited the growth, invasive, migration and adhesion ability of BEL-7402 cells and reduced the rate of colony formation in dose-dependent.
  
  
  CONCLUSIONS
  Phloretin can inhibit BEL-7402 cells' malignant pheotype.
authors.affiliation: Department of Chemistry, Guangdong Medical College, Zhanjiang 524023, China. luohui@gdmc.edn.cn
authors.forename: Hui
authors.initials: H
authors.lastname: Luo
authors.forename: Ya-Jun
authors.initials: YJ
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Jiang-Qin
authors.initials: JQ
authors.lastname: Liu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002448:Cell Adhesion / Q000187:drug effects; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D010641:Phenotype; D010693:Phloretin / Q000008:administration & dosage / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010693:Phloretin