Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety.
A series of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety were synthesized. Their structures were confirmed by (1)H NMR, (13)C NMR, and elemental analysis. The preliminary bioassays showed that all of the title compounds had low acaricidal activity against Tetranychus cinnabarinus . However, most of them exhibited excellent insecticidal activity against Aphis medicagini at the dosage of 0.5 mg/mL, and some compounds still showed good insecticidal activity against A. medicagini even at the dosage of 0.2 mg/mL. Meanwhile, some title compounds displayed fungicidal and plant growth regulatory activities.
Dai
Hong
H
State Key Laboratory of Elemento-Organic Chemistry and Tianjin Key Laboratory of Pesticide Science, Nankai University, Tianjin, People's Republic of China.
Li
Yong-Qiang
YQ
Du
Ding
D
Qin
Xue
X
Zhang
Xin
X
Yu
Hai-Bo
HB
Fang
Jian-Xin
JX
D000818:Animals; D001042:Aphids; D005659:Fungicides, Industrial / Q000494:pharmacology; D007306:Insecticides / Q000008:administration & dosage / Q000138:chemical synthesis*; D010091:Oximes / Q000008:administration & dosage / Q000138:chemical synthesis*; D010937:Plant Growth Regulators / Q000494:pharmacology; D011720:Pyrazoles / Q000008:administration & dosage / Q000138:chemical synthesis*; D013844:Thiazoles / Q000737:chemistry*
D005659:Fungicides, Industrial; D007306:Insecticides; D010091:Oximes; D010937:Plant Growth Regulators; D011720:Pyrazoles; D013844:Thiazoles