[Not Available].
The determination of weak acids in concentrated quaternary ammonium salt medium is proposed. In this type of solvent, which has few hydrogen bonds, complexation arises through homoconjugation or heteroconjugation in the presence of weak acids or bases; this enhances the acidity of the conjugate acid-base couples and makes them directly titratable. The procedure is applicable to determination of theobromine and theophylline with silver nitrate in concentrated tetrabutylammonium acetate medium. These compounds are titrated as weak acids and not as their conjugate bases.
Baylocq
D
D
Laboratoire de Chimie Analytique, Faculté de Pharmacie de l'Université Paris Sud, 1 Rue J. B. Clément, 92296 Chatenay-Malabry, France.
Kayata
W
W
Pellerin
F
F