Colorimetric determination of two fenamates in capsule dosage form.
The colorimetric determination of mefenamic acid and flufenamic acid with potassium ferricyanide in sodium hydroxide medium is described. The orange product is measured at 464 nm. The molar absorptivities are 1.9 x 10(3) and 2.9 x 10(3) 1.mole(-1).cm(-1) for mefenamic acid and flufenamic acid, respectively. The method has been applied successfully to the determination of these drugs in capsules.
Mahrous
M S
MS
Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt.
Abdel-Khalek
M M
MM
Abdel-Hamid
M E
ME