title: [Orbital pseudotumors and Riedel's thyroiditis: case report].
abstract: BACKGROUND
  We report a case of a patient with orbital pseudotumors associated with Riedel's thyroiditis. This association of unknown etiology may be related to idiopathic multifocal fibrosclerosis that includes retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Riedel's thyroiditis, and orbital pseudotumors.
  
  
  METHODS
  A 44-year-old woman was referred for a bilateral inflammatory malignant exophthalmos with progressive optical neuropathy (bilateral visual acuity<1/20). Imaging studies demonstrated bilateral exophthalmos (grade III) with compression of the both optic nerves by extensive tumoral infiltration. The general work-up showed a compressive goiter, with the histopathologic examination establishing the diagnosis of Riedel's thyroiditis. Orbital biopsy and antithyroid antibody testing were not contributive. Systemic corticosteroid associated with total thyroidectomy resulted in regression of the symptoms within 3 months.
  
  
  CONCLUSIONS
  The coexistence of bilateral orbital pseudotumor and Riedel's thyroiditis is the most common situation found for idiopathic multifocal fibrosclerosis. We discuss the differential diagnosis with thyroid-associated orbitopathy and orbital lymphoma. This observation is original because the diagnosis was reached by ophthalmic manifestation. The ophthalmologist should be able to identify this pathology to optimize the diagnostic and the therapeutic strategy.
  
  
  CONCLUSIONS
  In case of exophthalmos, a complete assessment should be made, including radiological and histopathological orbital and thyroid work-up.
authors.affiliation: Service d'Ophtalmologie, Centre Hospitalo-Universitaire Nord, Marseille, France. gire.julien@hotmail.fr
authors.forename: J
authors.initials: J
authors.lastname: Gire
authors.forename: S
authors.initials: S
authors.lastname: Guigou
authors.forename: G
authors.initials: G
authors.lastname: Darrason
authors.forename: S
authors.initials: S
authors.lastname: Carpentier
authors.forename: D
authors.initials: D
authors.lastname: Denis
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002291:Carcinoma, Papillary / Q000150:complications / Q000601:surgery; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology*; D005260:Female; D005355:Fibrosis; D006042:Goiter / Q000150:complications* / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008223:Lymphoma / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009408:Nerve Compression Syndromes / Q000209:etiology; D009901:Optic Nerve Diseases / Q000209:etiology; D009918:Orbital Neoplasms / Q000175:diagnosis; D016727:Orbital Pseudotumor / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000150:complications / Q000601:surgery; D013965:Thyroidectomy; D013966:Thyroiditis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones