title: EEG functional connectivity in term age extremely low birth weight infants.
abstract: OBJECTIVE
  The hypothesis is tested that electrocortical functional connectivity (quantified by coherence) of extremely low birth weight (ELBW) infants, measured at term post-menstrual age, has regional differences from that of full term infants.
  
  
  METHODS
  128 lead EEG data were collected during sleep from 8 ELBW infants with normal head ultrasound exams and 8 typically developing full term infants. Regional spectral power and coherence were calculated.
  
  
  RESULTS
  No significant regional differences in EEG power were found between infant groups. However, compared to term infants, ELBW infants had significantly reduced interhemispheric coherence (in frontal polar and parietal regions) and intrahemispheric coherence (between frontal polar and parieto-occipital regions) in the 1-12Hz band but increased interhemispheric coherence between occipital regions in the 24-50Hz band.
  
  
  CONCLUSIONS
  ELBW infants at term post-menstrual age manifest regional differences in EEG functional connectivity as compared to term infants.
  
  
  CONCLUSIONS
  Distinctive spatial patterns of electrocortical synchrony are found in ELBW infants. These regional patterns may presage regional alterations in the structure of the cortex.
authors.affiliation: Department of Pediatrics, Columbia University, USA.
authors.forename: Philip G
authors.initials: PG
authors.lastname: Grieve
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Isler
authors.forename: Asya
authors.initials: A
authors.lastname: Izraelit
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Peterson
authors.forename: William P
authors.initials: WP
authors.lastname: Fifer
authors.forename: Michael M
authors.initials: MM
authors.lastname: Myers
authors.forename: Raymond I
authors.initials: RI
authors.lastname: Stark
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D007839:Functional Laterality; D006801:Humans; D052577:Infant, Extremely Low Birth Weight / Q000502:physiology*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D012815:Signal Processing, Computer-Assisted; D012890:Sleep / Q000502:physiology; D013057:Spectrum Analysis; D055815:Young Adult