title: Synthesis of 6H-indolo[2,3-b]quinoxaline-N-glycosides and their cytotoxic activity against human ceratinocytes (HaCaT).
abstract: N-glycosides of 6H-indolo[2,3-b]quinoxalines were prepared and structurally characterized. The synthesis relies on the cyclocondensation of isatine-N-glycosides with 1,2-diaminobenzenes. Some products exhibit weak cytotoxic activity against human ceratinocytes (HaCaT).
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.
authors.forename: Katrin Marie
authors.initials: KM
authors.lastname: Driller
authors.forename: Stefanie
authors.initials: S
authors.lastname: Libnow
authors.forename: Martin
authors.initials: M
authors.lastname: Hein
authors.forename: Manuela
authors.initials: M
authors.lastname: Harms
authors.forename: Kristian
authors.initials: K
authors.lastname: Wende
authors.forename: Michael
authors.initials: M
authors.lastname: Lalk
authors.forename: Dirk
authors.initials: D
authors.lastname: Michalik
authors.forename: Helmut
authors.initials: H
authors.lastname: Reinke
authors.forename: Peter
authors.initials: P
authors.lastname: Langer
mesh_terms: D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity*; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D015603:Keratinocytes / Q000187:drug effects*; D011810:Quinoxalines / Q000737:chemistry*
chemical_list: D006027:Glycosides; D007211:Indoles; D011810:Quinoxalines; C030374:indole