title: Simultaneous determination of acetaminophen and caffeine in tablet preparations by partial least-squares multivariate spectrophotometric calibration.
abstract: The use of partial least-squares spectrophotometric calibration for the simultaneous determination of analgesic tablets in a multicomponent formulation is presented. This method is applied to the determination of acetaminophen and caffeine in tablet preparations. The results show that these components in a molar ratio of about 21:1 in tablets have been determined simultaneously with high precision.
authors.affiliation: Yildiz University, Department of Chemistry, Sişli, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Bozdogan
authors.forename: A M
authors.initials: AM
authors.lastname: Acar
authors.forename: G K
authors.initials: GK
authors.lastname: Kunt