title: Analysis of 2-ethylhexyl-p-methoxycinnamate in sunscreen products by HPLC and Raman spectroscopy.
abstract: The analyses of 2-ethylhexyl-p-methoxycinnamate (EHMC) using HPLC and Raman spectroscopy have been undertaken and compared. EHMC, which is one of the most widely used sunscreen agents in suncare products in the US, exhibits a strong Raman signal. This signal clearly appears in both ethanol solutions of EHMC as well as in commercial sunscreen lotions containing this sun screen agent. A method for the direct detection and analysis of EHMC has been developed using Raman spectroscopy. This was accomplished by correlating the Raman intensities with the HPLC assays for a series of prototype suncare formulations. Based upon this information, it would be possible to employ Raman spectroscopy as an in-process control method in the commercial production of suncare products containing EHMC. The possibility of applying surface-enhanced Raman scattering for trace analysis was discussed.
authors.affiliation: Department of Chemistry, The University of Memphis, Memphis, TN 38152, USA.
authors.forename: J
authors.initials: J
authors.lastname: Cheng
authors.forename: Y S
authors.initials: YS
authors.lastname: Li
authors.forename: R
authors.initials: R
authors.lastname: L Roberts
authors.forename: G
authors.initials: G
authors.lastname: Walker