A case of primary hypothyroidism causing central nervous system atherosclerosis in a dog.
A 2-year-old, castrated male, Australian shepherd was presented with a history of chronic mild ataxia, obesity, and lethargy. The dog was treated with levothyroxine, but the ataxia worsened. Cranial nerve abnormalities developed and the dog was euthanized. Postmortem examination revealed marked thyroid gland atrophy and widespread, severe central nervous system atherosclerosis.
Blois
Shauna L
SL
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Ontario N1G 2W1. sblois@uoguelph.ca
Poma
Roberto
R
Stalker
Margaret J
MJ
Allen
Dana G
DG
D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D002537:Intracranial Arteriosclerosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D008297:Male; D013961:Thyroid Gland / Q000473:pathology*