title: Deep venous thrombosis caused by congenital malformation of the inferior vena cava and heterozygous factor V leiden presenting as venous claudication.
abstract: A case of an 18-year-old man with deep venous thrombosis of the lower limbs caused by hypoplasia of the inferior vena cava in combination with heterozygous factor V Leiden is presented. Both anomalies were found when the patient complained of venous claudication in both thighs. Inferior vena cava malformation is a rare condition and may predispose to the development of deep venous thrombosis. This patient was at an even higher risk for deep venous thrombosis as the inferior vena cava malformation was combined with a hypercoagulable state.
authors.affiliation: Department of Emergency, Brugmann University Hospital, Brussels, Belgium. garyfass@gmail.com
authors.forename: Gary
authors.initials: G
authors.lastname: Fass
authors.forename: Damry
authors.initials: D
authors.lastname: Nasroolah
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Cavenaile
mesh_terms: D000293:Adolescent; D005165:Factor V / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D007383:Intermittent Claudication / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics; D008297:Male; D011859:Radiography; D012307:Risk Factors; D016896:Treatment Outcome; D014682:Vena Cava, Inferior / Q000002:abnormalities* / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics
chemical_list: C095381:factor V Leiden; D005165:Factor V