title: VirusMINT: a viral protein interaction database.
abstract: Understanding the consequences on host physiology induced by viral infection requires complete understanding of the perturbations caused by virus proteins on the cellular protein interaction network. The VirusMINT database (http://mint.bio.uniroma2.it/virusmint/) aims at collecting all protein interactions between viral and human proteins reported in the literature. VirusMINT currently stores over 5000 interactions involving more than 490 unique viral proteins from more than 110 different viral strains. The whole data set can be easily queried through the search pages and the results can be displayed with a graphical viewer. The curation effort has focused on manuscripts reporting interactions between human proteins and proteins encoded by some of the most medically relevant viruses: papilloma viruses, human immunodeficiency virus 1, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, herpes viruses and Simian virus 40.
authors.affiliation: Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.
authors.forename: Andrew
authors.initials: A
authors.lastname: Chatr-aryamontri
authors.forename: Arnaud
authors.initials: A
authors.lastname: Ceol
authors.forename: Daniele
authors.initials: D
authors.lastname: Peluso
authors.forename: Aurelio
authors.initials: A
authors.lastname: Nardozza
authors.forename: Simona
authors.initials: S
authors.lastname: Panni
authors.forename: Francesca
authors.initials: F
authors.lastname: Sacco
authors.forename: Michele
authors.initials: M
authors.lastname: Tinti
authors.forename: Alex
authors.initials: A
authors.lastname: Smolyar
authors.forename: Luisa
authors.initials: L
authors.lastname: Castagnoli
authors.forename: Marc
authors.initials: M
authors.lastname: Vidal
authors.forename: Michael E
authors.initials: ME
authors.lastname: Cusick
authors.forename: Gianni
authors.initials: G
authors.lastname: Cesareni
mesh_terms: D003196:Computer Graphics; D030562:Databases, Protein; D025941:Protein Interaction Mapping; D014764:Viral Proteins / Q000378:metabolism*
chemical_list: D014764:Viral Proteins