title: Hyperzincemia and hypercalprotectinemia: unsuccessful treatment with tacrolimus.
abstract: We report on a 5-year-old boy with hyperzincemia and hypercalprotectinemia. Treatment began with Tacrolimus at the age of 4 years and 6 months. Despite an initial correction of clinical and biological symptoms, zincemia and calprotectinemia progressively worsened with secondary reappearance of symptoms.
  
  
  CONCLUSIONS
  Tacrolimus seems to have a transient effect in the treatment of Hyperzincemia and hyperprolactinemia.
authors.affiliation: Service de Génétique Médicale, Centre Hospitalo-Universitaire, Nantes, France. bertrand.isidor@chu-nantes.fr
authors.forename: B
authors.initials: B
authors.lastname: Isidor
authors.forename: S
authors.initials: S
authors.lastname: Poignant
authors.forename: N
authors.initials: N
authors.lastname: Corradini
authors.forename: M
authors.initials: M
authors.lastname: Fouassier
authors.forename: P
authors.initials: P
authors.lastname: Quartier
authors.forename: J
authors.initials: J
authors.lastname: Roth
authors.forename: G
authors.initials: G
authors.lastname: Picherot
mesh_terms: D002675:Child, Preschool; D006801:Humans; D039841:Leukocyte L1 Antigen Complex / Q000097:blood*; D008297:Male; D008659:Metabolic Diseases / Q000097:blood* / Q000188:drug therapy*; D016559:Tacrolimus / Q000627:therapeutic use*; D017211:Treatment Failure; D015032:Zinc / Q000097:blood*
chemical_list: D039841:Leukocyte L1 Antigen Complex; D015032:Zinc; D016559:Tacrolimus