title: Morphological properties of the action-observation cortical network in adolescents with low and high resistance to peer influence.
abstract: Children with high resistance to peer influences differ from their low-resistance counterparts in the degree of functional connectivity in fronto-parietal and prefrontal cortical networks. Here we explored the possibility that the degree of morphological similarities across the same cortical regions also varies as a function of this behavioral trait. Using structural magnetic-resonance (MR) images, we measured cortical thickness in a total of 295 adolescents (12 to 18 years of age). We found that inter-regional correlations in cortical thickness increased with the resistance to peer influence (RPI); this was especially the case, in female adolescents, in the premotor and prefrontal networks. We also observed significant differences between the adolescents with high and low RPI scores in their general intelligence and the scores of positive youth development. We suggest that these morphological findings might reflect differences, between adolescents with high vs. low resistance to peer influences, in a repeated and concurrent engagement of these networks in social context.
authors.affiliation: University of Nottingham, Nottingham, UK. tomas.paus@nottingham.ac.uk
authors.forename: Tomás
authors.initials: T
authors.lastname: Paus
authors.forename: Roberto
authors.initials: R
authors.lastname: Toro
authors.forename: Gabriel
authors.initials: G
authors.lastname: Leonard
authors.forename: Jacqueline V
authors.initials: JV
authors.lastname: Lerner
authors.forename: Richard M
authors.initials: RM
authors.lastname: Lerner
authors.forename: Michel
authors.initials: M
authors.lastname: Perron
authors.forename: G Bruce
authors.initials: GB
authors.lastname: Pike
authors.forename: Louis
authors.initials: L
authors.lastname: Richer
authors.forename: Laurence
authors.initials: L
authors.lastname: Steinberg
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D002648:Child; D003071:Cognition / Q000502:physiology; D005260:Female; D006801:Humans; D007360:Intelligence / Q000502:physiology; D007398:Interpersonal Relations; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D009483:Neuropsychological Tests; D019370:Observation; D010379:Peer Group; D012737:Sex Factors; D012919:Social Behavior