title: Structural investigation of a new organic antiseptic: Taurolidine A spectroscopic study of its stability and equilibria in various solvents.
abstract: (1)H and (13)C NMR investigations of aqueous solutions of Taurolidine and Tauroflex have been made to determine their stability. This study revealed two successive equilibria, leading particularly to Taurultam-methylol (in 15% proportion) from a 0.5% Taurolidine solution. The methylol derivative is supposed to be the component active against bacteria and their endotoxins.
authors.affiliation: Laboratoires de Toxicologie et de Physique, Faculté de Pharmacie, Rue du Professeur Laguesse, 59045 Lille, France.
authors.forename: F
authors.initials: F
authors.lastname: Erb
authors.forename: N
authors.initials: N
authors.lastname: Febvay
authors.forename: M
authors.initials: M
authors.lastname: Imbenotte