title: Determination of the binding constant for the inclusion complex between procaine hydrochloride and beta-cyclodextrin by capillary electrophoresis.
abstract: The apparent electrophoretic mobilities of procaine hydrochloride (mu(i)) in a series of concentration of beta-cyclodextrin were measured directly by capillary electrophoresis technology. A new mathematical treatment method is proposed, which based on the fact that the molar ratio of the inclusion complex was 1:1 established by spectrophotometry. Using the proposed method, the binding constant of the inclusion complex of procaine hydrochloride with beta-cyclodextrin can be obtained easily. The determination result was in correspondence with those of the spectrophotometric and fluorescence methods.
authors.affiliation: Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, PR China.
authors.forename: Nianbing
authors.initials: N
authors.lastname: Li
authors.forename: Jianping
authors.initials: J
authors.lastname: Duan
authors.forename: Hongqing
authors.initials: H
authors.lastname: Chen
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen