title: Michigan molecular interactions r2: from interacting proteins to pathways.
abstract: Molecular interaction data exists in a number of repositories, each with its own data format, molecule identifier and information coverage. Michigan molecular interactions (MiMI) assists scientists searching through this profusion of molecular interaction data. The original release of MiMI gathered data from well-known protein interaction databases, and deep merged this information while keeping track of provenance. Based on the feedback received from users, MiMI has been completely redesigned. This article describes the resulting MiMI Release 2 (MiMIr2). New functionality includes extension from proteins to genes and to pathways; identification of highlighted sentences in source publications; seamless two-way linkage with Cytoscape; query facilities based on MeSH/GO terms and other concepts; approximate graph matching to find relevant pathways; support for querying in bulk; and a user focus-group driven interface design. MiMI is part of the NIH's; National Center for Integrative Biomedical Informatics (NCIBI) and is publicly available at: http://mimi.ncibi.org.
authors.affiliation: Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: V Glenn
authors.initials: VG
authors.lastname: Tarcea
authors.forename: Terry
authors.initials: T
authors.lastname: Weymouth
authors.forename: Alex
authors.initials: A
authors.lastname: Ade
authors.forename: Aaron
authors.initials: A
authors.lastname: Bookvich
authors.forename: Jing
authors.initials: J
authors.lastname: Gao
authors.forename: Vasudeva
authors.initials: V
authors.lastname: Mahavisno
authors.forename: Zach
authors.initials: Z
authors.lastname: Wright
authors.forename: Adriane
authors.initials: A
authors.lastname: Chapman
authors.forename: Magesh
authors.initials: M
authors.lastname: Jayapandian
authors.forename: Arzucan
authors.initials: A
authors.lastname: Ozgür
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Tian
authors.forename: Jim
authors.initials: J
authors.lastname: Cavalcoli
authors.forename: Barbara
authors.initials: B
authors.lastname: Mirel
authors.forename: Jignesh
authors.initials: J
authors.lastname: Patel
authors.forename: Dragomir
authors.initials: D
authors.lastname: Radev
authors.forename: Brian
authors.initials: B
authors.lastname: Athey
authors.forename: David
authors.initials: D
authors.lastname: States
authors.forename: H V
authors.initials: HV
authors.lastname: Jagadish
mesh_terms: D003196:Computer Graphics; D030562:Databases, Protein; D025941:Protein Interaction Mapping; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D014584:User-Computer Interface
chemical_list: D011506:Proteins