Kinetic determination of iodide, based on the chlorpromazine-bromate reaction.
A kinetic method based on the catalytic effect of iodide on the chlorpromazine-bromate reaction is described. The reaction was followed spectrophotometrically by measuring the increase in the absorbance at 525 nm. Under optimal experimental conditions (10(-4)M chlorpromazine hydrochloride, 1.5(itM) phosphoric acid, 5 x 10(-4)M potassium bromate, 40 degrees ), iodide was determined between 5 and 70 ng/ml by the tangent method. The influence of reaction variables, the precision and accuracy of the method and the effect of foreign ions were studied. The procedure was applied to the determination of iodide in iodinated salts and in rat thyroid.
Viñas
P
P
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Murcia, Spain.
Cordoba
M H
MH
Sanchez-Pedreño
C
C