Relationship between oral Kaposi 's sarcoma and HAART: contribution of two case reports.
Two HIV infected patients not receiving Highly Active Antiretroviral Treatment (HAART) presented with epidemic Kaposi's sarcoma of the oral cavity. One patient initially refused HAART, but when the lesion became large enough to be noticeable he agreed to HAART associated with excision of the intraoral lesion by CO2 laser. The other patient developed KS and progressed to AIDS at two years after ceasing HAART due to adverse effects; he was referred to hospital for renewed administration of HAART. In both cases, the lesions observed in the oral cavity were the first clinical manifestation of AIDS. These reports underline the close relationship between the use of HAART and the control of KS lesions, highlighting the important role of the dentist in the identification and early diagnosis of these oral lesions.
Campo-Trapero
Julián
J
Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, UCM. Avda Complutense s/n, 28080 Madrid, Spain. jcampo@odon.ucm.es
Del Romero-Guerrero
Jorge
J
Cano-Sánchez
Jorge
J
Rodríguez-Martín
Carmen
C
Martínez-González
José Ma
JM
Bascones-Martínez
Antonio
A
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000209:etiology* / Q000517:prevention & control*; D012514:Sarcoma, Kaposi / Q000209:etiology* / Q000517:prevention & control*; D055815:Young Adult