Subcutaneous microdialysis probe coupled with glucose biosensor for in vivo continuous monitoring.
Microdialysis probes have been tested to evaluate the influence of flow-rate, probe dimensions and temperature when used as sampling systems inserted subcutaneously for in vivo monitoring of glucose. The probe was coupled with a glucose biosensor obtained from a thin layer electrochemical cell generally used as detector for liquid chromatography. Glucose oxidase was immobilized on a nylon net membrane and it was placed over an acetate cellulose membrane into the cell in contact with the platinum anode.
Moscone
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Dipartimento di Scienze e Tecnologie Chimiche, Universitá di Roma Tor Vergata, 00173 Roma, Italy.
Pasini
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Mascini
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