Examination of guanosine and xanthosine nucleotides by HPLC and electrochemical detection.
The suitability of electrochemical detection (ECD) following HPLC separation of guanosine, xanthosine and adenosine nucleotides has been evaluated. Separation of five monophosphates of guanosine was achieved by using a reversed-phase column; di- and triphosphates have also been separated from monophosphates. Adenosine compounds are insensitive to ECD.
Maria Ghe
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A
Scuola di Specializzazione in Chimica Analitica, Dipartimento di Chimica "G. Ciamician", Universitá de Bologna, via Selmi, 2-40126 Bologna, Italy.
Chiavari
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G
Bergamini
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C