title: Christopher Hughes: an in vitro model for the study of angiogenesis (interview).
abstract: Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.
authors.forename: Christopher C W
authors.initials: CC
authors.lastname: Hughes
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D002478:Cells, Cultured; D042783:Endothelial Cells / Q000166:cytology / Q000502:physiology*; D005347:Fibroblasts / Q000166:cytology / Q000502:physiology*; D006801:Humans; D018919:Neovascularization, Physiologic / Q000502:physiology*