Neuronal distortions of reward probability without choice.
Reward probability crucially determines the value of outcomes. A basic phenomenon, defying explanation by traditional decision theories, is that people often overweigh small and underweigh large probabilities in choices under uncertainty. However, the neuronal basis of such reward probability distortions and their position in the decision process are largely unknown. We assessed individual probability distortions with behavioral pleasantness ratings and brain imaging in the absence of choice. Dorsolateral frontal cortex regions showed experience dependent overweighting of small, and underweighting of large, probabilities whereas ventral frontal regions showed the opposite pattern. These results demonstrate distorted neuronal coding of reward probabilities in the absence of choice, stress the importance of experience with probabilistic outcomes and contrast with linear probability coding in the striatum. Input of the distorted probability estimations to decision-making mechanisms are likely to contribute to well known inconsistencies in preferences formalized in theories of behavioral economics.
Tobler
Philippe N
PN
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom. pnt21@cam.ac.uk
Christopoulos
George I
GI
O'Doherty
John P
JP
Dolan
Raymond J
RJ
Schultz
Wolfram
W
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D003657:Decision Making; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000166:cytology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009474:Neurons / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation / Q000379:methods; D011336:Probability; D012201:Reward
D010100:Oxygen