title: [Study on the sorption and isolation of shikimic acid by 717 anion exchange resin].
abstract: OBJECTIVE
  To establish a convenient, practical and environmental method for extracting and isolating shikimic acid.
  
  
  METHODS
  The content of shikimic acid was measured by RP-ion-pair HPLC, the effects of different pH, temperature, sample concentration and eluate concentration on 717 anion exchange resin were studied.
  
  
  RESULTS
  The yield of shikimic acid was 96.52% on the condition of 22 degrees C, pH > 6.5, 7.5 mg /ml sample concentration and 0.03 mol/L HCl eluting.
  
  
  CONCLUSIONS
  This method is feasible and suitable for the extraction and isolation of shikimic acid.
authors.affiliation: Chongqing Medical University, Chongqing 400016, China. malianjucq@126.com
authors.forename: Lian-Ju
authors.initials: LJ
authors.lastname: Ma
authors.forename: Xin
authors.initials: X
authors.lastname: Liu
authors.forename: Yu-Juan
authors.initials: YJ
authors.lastname: Zhuo
authors.forename: Lu-Rong
authors.initials: LR
authors.lastname: Yu
mesh_terms: D000837:Anion Exchange Resins / Q000737:chemistry*; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D006863:Hydrogen-Ion Concentration; D011786:Quality Control; D012117:Resins, Synthetic / Q000737:chemistry; D012765:Shikimic Acid / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D000837:Anion Exchange Resins; D000998:Antiviral Agents; D012117:Resins, Synthetic; D012765:Shikimic Acid