Clinical utility of selective esophageal manometry in a tertiary care setting.
OBJECTIVE
To evaluate the utility of selective esophageal manometry in clinical practice.


RESULTS
Retrospective data from 200 subjects was reviewed. Manometry was considered to be (1) high clinical utility when specific abnormality was identified resulting in therapeutic intervention, (2) low clinical utility when specific abnormality was identified without alteration of therapy, (3) limited clinical utility when manometry was normal. High, low, and limited clinical utility was noted in 47, 40, and 13% of instances. Manometry was of high utility in patients with dysphagia or non-cardiac chest pain (P < 0.05), and low utility in gastroesophageal reflux (P < 0.05).


CONCLUSIONS
(1) Esophageal manometry has high clinical utility in dysphagia after exclusion of structural disorders; and non-cardiac chest pain after careful exclusion of reflux. (2) Ineffective motility disorder has high association with gastroesophageal reflux disease but low clinical utility except in preoperative assessment for fundoplication. (3) Esophageal manometry is of high utility in clinical practice when used in conjunction with other diagnostic exclusions.
Mehendiratta
Vaibhav
V
Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
DiMarino
Anthony J
AJ
Cohen
Sidney
S
D000328:Adult; D000368:Aged; D002637:Chest Pain / Q000175:diagnosis*; D004935:Esophageal Diseases / Q000175:diagnosis*; D015154:Esophageal Motility Disorders / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D012189:Retrospective Studies