title: Impact of urodynamic based incontinence diagnosis on quality of life in women.
abstract: OBJECTIVE
  To characterize the effect of urodynamic diagnosis on degree of incontinence related bother and health related quality of life in a large, multi-ethnic population of women.
  
  
  METHODS
  Effects of multichannel urodynamic diagnosis, urethral competency, and other patient characteristics on abbreviated Urogenital Distress Inventory (UDI6) and Incontinence Impact Questionnaire (IIQ7) composite scores were analyzed retrospectively.
  
  
  RESULTS
  Six hundred eleven patients were included. Mean UDI6 and IIQ7 scores were significantly higher among patients with mixed incontinence, detrusor overactivity, urinary stress incontinence with overactive bladder, and negative studies compared to those with stress incontinence without OAB. The relative composite UDI6 and IIQ7 mean scores did not significantly differ between the mixed incontinence, detrusor overactivity, stress incontinence with OAB and negative study groups. UDI6 and IIQ7 scores were significantly higher among stress incontinent patients with intrinsic sphincter deficiency, but similar among mixed incontinent patients with intrinsic sphincter deficiency.
  
  
  CONCLUSIONS
  Urodynamic diagnoses of detrusor overactivity, mixed incontinence, and stress incontinence with overactive bladder are associated with significantly worse incontinence related bother and health related quality of life when compared to those with stress incontinence without OAB. These conditions appear to have similar degree of impact on incontinence related bother and quality of life. Patients presenting with symptoms of incontinence can suffer a similar compromise in quality of life despite a negative MCUD study.
authors.affiliation: Harbor-UCLA Medical Center, Torrance, California, USA. a.haessler@hotmail.com
authors.forename: Alexandra L
authors.initials: AL
authors.lastname: Haessler
authors.forename: John N
authors.initials: JN
authors.lastname: Nguyen
authors.forename: Narender N
authors.initials: NN
authors.lastname: Bhatia
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008875:Middle Aged; D010298:Parity; D017773:Pelvic Floor / Q000601:surgery; D011247:Pregnancy; D011788:Quality of Life; D012044:Regression Analysis; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014521:Urethra / Q000503:physiopathology; D014549:Urinary Incontinence / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology*; D016055:Urinary Retention / Q000523:psychology; D014563:Urodynamics / Q000502:physiology*; D013520:Urologic Surgical Procedures; D014596:Uterine Prolapse; D055815:Young Adult