title: A consideration of electrode polishing prior to application of pulsed amperometric detection.
abstract: An examination was made of the effect of electrode polishing on the direct pulsed amperometric detection (PAD) and indirect PAD response to penicillin G. The polishing procedure produced a temporary loss of sensitivity for both types of PAD, which over time relaxed back to higher levels. A temporary increase in the electrode kinetics can be observed as well, particularly for a PAD waveform in the crossover region between direct and indirect PAD. In extreme cases, the penicillin G response can undergo a complete polarity reversal. By observing post-polish equilibration times, it was recommended that the direct and indirect PAD user observe 3 and 5 h delay times, respectively, to insure stable electrode response following an electrode polish.
authors.affiliation: Department of Chemistry, Knox College, Galesburg, IL 61401 USA.
authors.forename: A
authors.initials: A
authors.lastname: Inoue
authors.forename: R L
authors.initials: RL
authors.lastname: Earley
authors.forename: M W
authors.initials: MW
authors.lastname: Lehmann
authors.forename: L E
authors.initials: LE
authors.lastname: Welch