"Pure by NMR"?
Integration of a (13)C-(1)H satellite peak of a given (12)C-(1)H parent resonance within a quantitative (1)H NMR spectrum and comparison to the minor component represents a simple protocol for the accurate determination of diastereoisomeric ratios of up to 1000:1 (i.e., 99.8% de).
Claridge
Timothy D W
TD
Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
Davies
Stephen G
SG
Polywka
Mario E C
ME
Roberts
Paul M
PM
Russell
Angela J
AJ
Savory
Edward D
ED
Smith
Andrew D
AD