title: Study of the tautomeric forms of 3,4-dihydroxyphenylacetic acid by carbon-13 nuclear magnetic resonance spectroscopy.
abstract: The pH-dependent (13)C chemical shifts indicate an approximately 1:1 ratio of the 3-OH:4-OH tautomeric forms of singly dissociated 3,4-dihydroxyphenylacetic acid. It is found that the (13)C chemical-shift method is an effective technique for determining tautomeric forms from pK values.
authors.affiliation: Kyoto College of Pharmacy, Kyoto 607, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ishimitsu
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: S
authors.initials: S
authors.lastname: Hirose