title: Registration of 4D time-series of cardiac images with multichannel Diffeomorphic Demons.
abstract: In this paper, we propose a generic framework for intersubject non-linear registration of 4D time-series images. In this framework, spatio-temporal registration is defined by mapping trajectories of physical points as opposed to spatial registration that solely aims at mapping homologous points. First, we determine the trajectories we want to register in each sequence using a motion tracking algorithm based on the Diffeomorphic Demons algorithm. Then, we perform simultaneously pairwise registrations of corresponding time-points with the constraint to map the same physical points over time. We show this trajectory registration can be formulated as a multichannel registration of 3D images. We solve it using the Diffeomorphic Demons algorithm extended to vector-valued 3D images. This framework is applied to the inter-subject non-linear registration of 4D cardiac CT sequences.
authors.affiliation: INRIA - Asclepios Research Project, Sophia Antipolis, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Peyrat
authors.forename: Hervé
authors.initials: H
authors.lastname: Delingette
authors.forename: Maxime
authors.initials: M
authors.lastname: Sermesant
authors.forename: Xavier
authors.initials: X
authors.lastname: Pennec
authors.forename: Chenyang
authors.initials: C
authors.lastname: Xu
authors.forename: Nicholas
authors.initials: N
authors.lastname: Ayache
mesh_terms: D000465:Algorithms; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*