[Fluorquinolone associated tendon rupture].
We report the case of a 38-year-old patient with a rupture of the right Achilles tendon after physical exercise. A few days before he had been treated with ciprofloxacine 500mg bid for chlamydial urethritis. We discuss know risk factors for Achilles tendon ruptures and the possible contribution of ciprofloxacin and fluorquinolones in this case.
Rätz Bravo
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A
Klinische Pharmakologie and Toxikologie, Departement Innere Medizin, Universitätsspital Basel, Basel. raetza@uhbs.ch
Stoll
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R
Bürr
P
P
Haschke
M
M
D000125:Achilles Tendon / Q000187:drug effects* / Q000293:injuries; D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001265:Athletic Injuries / Q000139:chemically induced*; D002690:Chlamydia Infections / Q000188:drug therapy; D002939:Ciprofloxacin / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000009:adverse effects / Q000627:therapeutic use; D012307:Risk Factors; D012422:Rupture, Spontaneous; D012916:Soccer / Q000293:injuries*; D013557:Switzerland; D013708:Tendon Injuries / Q000139:chemically induced*; D014526:Urethritis / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D002939:Ciprofloxacin; D015242:Ofloxacin