title: Spectrophotometric determination of clofibrate.
abstract: A sensitive method for the rapid and accurate determination of clofibrate by hydroxamic acid formation is described. Hydroxylamine hydrochloride is reacted with clofibrate in alkaline medium to give 4-chlorophenoxyisobutyrohydroxamic acid, which forms a purple complex with iron(III) in acidic medium. Common excipients do not interfere.
authors.affiliation: Pharmacy Department, Faculty of Technology and Engineering, M.S. University of Baroda, Kalabhavan, Baroda 390 001, India.
authors.forename: Y K
authors.initials: YK
authors.lastname: Agrawal
authors.forename: D R
authors.initials: DR
authors.lastname: Patel