title: Single-point titration of metal ions and ligands by measuring change in pH.
abstract: A single-point titration method is described for the determination of metal ions and ligands. The method is based on deprotonation of a ligand on complexation with a metal. The resultant change in pH is used to calculate the concentration of the analyte. The limits and advantages of the method are discussed. Four selected systems, Pb(2+)-HPO(2-)(4), Cu(2+)-HCO(-)(3), Cd(2+)-EDTA and Ni(2+)-ethylenediamine are used to demonstrate the validity of the equations. The method is applied to determination of total carbonate in serum.
authors.affiliation: Department of Analytical Chemistry, Abo Akademi, 20500 Abo Turku, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Lewenstam
authors.forename: A
authors.initials: A
authors.lastname: Ivaska
authors.forename: E
authors.initials: E
authors.lastname: Wänninen