title: Determination of l-histidine by modified carbon paste electrode using tetra-3,4-pyridinoporphirazinatocopper(II).
abstract: This paper describes a potentiometric method for determination of l-histidine (l-his) in aqueous media, using a carbon paste electrode modified with tetra-3,4-pyridinoporphirazinatocopper(II) (Cu (3,4tppa)). The electrode exhibits linear response to the logarithm of the concentration of l-histidine from 2.4 x 10(-5) to 1.0 x 10(-2)M, with a response slope of -49.5 +/- 1mV and response time of about 1.5min. The detection limit according to IUPAC recommendation was 2.0 x 10(-5)M. The proposed electrode shows a good selectivity for l-his over a wide variety of anions. This chemically modified carbon paste electrode was successfully used for the determination of l-his in a synthetic serum and RANDOX control serum solutions.
authors.affiliation: Chemistry Department, Shiraz University, Shiraz 71454, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Abbaspour
authors.forename: A
authors.initials: A
authors.lastname: Ghaffarinejad
authors.forename: E
authors.initials: E
authors.lastname: Safaei