Making artemisinin.
The possibilities for the production of the antimalarial artemisinin by biological and chemical means are explored. These include native biosynthesis, genetic modification of Artemisia annua and other plants, engineering of microbes, total and partial chemical synthesis and combinations of the above.
Covello
Patrick S
PS
Plant Biotechnology Institute, SK, Canada. Patrick.Covello@nrc-cnrc.gc.ca
D019306:Artemisia / Q000235:genetics / Q000378:metabolism; D037621:Artemisinins / Q000138:chemical synthesis* / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005818:Genetic Engineering; D015394:Molecular Structure
D037621:Artemisinins; C031327:artemisinin