title: Survival of dogs following surgical excision of histologically well-differentiated melanocytic neoplasms of the mucous membranes of the lips and oral cavity.
abstract: Postsurgical follow-up information was obtained on 64 dogs with 69 histologically well-differentiated melanocytic neoplasms that involved the mucous membranes of the lips and oral cavity. The patients received no adjunct therapy. Sixty one of 64 dogs (95%) were alive at the end of the study or had died of causes unrelated to the tumor, with a mean survival of 23.4 months and a median survival of 34 months after surgery. Twenty-eight dogs alive at the end of the study had a mean survival of 31.3 months after surgery. There were 2 dogs, which had recurrent tumors, that were still alive at the end of the study. All dogs that died of tumor-related causes (3) and all dogs with recurrent tumors (2) had tumors in the oral cavity. Results of this study indicate that a favorable clinical course and prolonged survival can be expected in most dogs with histologically well-differentiated melanocytic neoplasms of the mucous membranes of the lips and oral cavity, with only local excision of the lesions and no adjunct therapy.
authors.affiliation: Animal Reference Pathology Division, ARUP Laboratories, Salt Lake City, UT 84108, USA. esplindg@aruplab.com
authors.forename: D G
authors.initials: DG
authors.lastname: Esplin
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000401:mortality / Q000601:surgery*; D004285:Dogs; D008048:Lip Neoplasms / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D008545:Melanoma / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D009062:Mouth Neoplasms / Q000401:mortality / Q000601:surgery / Q000662:veterinary*; D012189:Retrospective Studies