title: Allene-alkyne cross-coupling for stereoselective synthesis of substituted 1,4-dienes and cross-conjugated trienes.
abstract: Titanium-mediated cross-coupling of allenic alcohols with alkynes has been investigated. Divergent reaction pathways were discovered that provide either stereodefined 1,4-dienes or substituted cross-conjugated trienes. In short, allene substitution plays a critical role in the determination of reaction pathway.
authors.affiliation: Department of Chemistry, Yale Univeristy, New Haven, Connecticut 06520-8107.
authors.forename: Heidi L
authors.initials: HL
authors.lastname: Shimp
authors.forename: Alissa
authors.initials: A
authors.lastname: Hare
authors.forename: Martin
authors.initials: M
authors.lastname: McLaughlin
authors.forename: Glenn C
authors.initials: GC
authors.lastname: Micalizio