title: Use of amino-carbonyl reaction and chemiluminescence detection to the flow-injection determination of some amino acids.
abstract: Some amino acids were found to react with carbonyl functional groups of humic acid. Products of this reaction give strong chemiluminescence during their oxidation with N-bromosuccinimide (NBS) in alkaline solution. Humic acids from different sources produced similiar signal magnitude. This effect was employed to the flow-injection determination of glycine and arginine in pharmaceutical formulations with considerable selectivity against different amino compounds. The proposed method is fast and simple. Detection limit is 0.20 and 0.25 mg.l(-1) for glycine and arginine respectively, and 115 samples per h can be determined.
authors.affiliation: Institute of Chemistry, University of Białystok, al. J. Piłsudskiego 11/4, 15-443 Białystok, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Michałowski
authors.forename: A
authors.initials: A
authors.lastname: Kojło