Effect of preload on left ventricular longitudinal strain by 2D speckle tracking.
BACKGROUND
Peak systolic longitudinal strain (PSLS) obtained using the 2D speckle tracking method is a novel indicator of the long-axis function of the left ventricle (LV). We used the 2D strain profile to examine the effect of preload reduction by hemodialysis (HD) on LV PSLS in patients with end-stage renal disease (ESRD).


RESULTS
Twenty-nine pairs of echocardiographic evaluations were obtained before and after dialysis. Global LV PSLS was -18.4 +/- 2.9%, at baseline and decreased to -16.9 +/- 3.2% after HD (P < 0.001). Segmental analysis showed that the decrease in PSLS after dialysis was most prominent in mid-LV segments (-17.1 +/- 3.5% vs. -15.4 +/- 3.4%, P < 0.001).


CONCLUSIONS
PSLS obtained from the 2D strain profile is a reliable parameter that may be useful for evaluating LV systolic long-axis function. However, PSLS should be applied cautiously in ESRD patients because it could be affected by dialysis.
Choi
Jin-Oh
JO
Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyukwan University School of Medicine, Seoul, Korea.
Shin
Dae-Hee
DH
Cho
Sung Won
SW
Song
Young Bin
YB
Kim
Jun Hyung
JH
Kim
Yoon Goo
YG
Lee
Sang-Chol
SC
Park
Seung Woo
SW
D000465:Algorithms; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology*