Relationship between sarcopenia and fracture risks in obese postmenopausal women.
It is known that obesity is inversely correlated with fracture risk. It remains unclear if a low muscle mass (sarcopenia) modulates the relationship between obesity and bone mass density. Twenty-seven obese women were matched for total fat mass (+/- 0.5 kg) and age (+/- 4 yrs) and divided in 3 equal groups: class II sarcopenic, class I sarcopenic, and nonsarcopenic. Body composition (DXA) and dietary intake were measured. Our results suggest that obesity may offer some protection against osteoporosis, even in sarcopenic postmenopausal women. However, further studies are needed to examine the actual implication of these results on a clinical standpoint.
Aubertin-Leheudre
Mylène
M
Faculty of Physical and Education of Sports, Research Centre on Aging, University of Sherbrooke, 1036 Belvédère Sud, Sherbrooke, Québec, J1H 4C4, Canada.
Lord
Christine
C
Labonté
Mélissa
M
Khalil
Abdelouahed
A
Dionne
Isabelle J
IJ
D015502:Absorptiometry, Photon; D015992:Body Mass Index; D005260:Female; D050723:Fractures, Bone / Q000150:complications* / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D009133:Muscular Atrophy / Q000150:complications* / Q000503:physiopathology*; D009765:Obesity / Q000150:complications*; D017698:Postmenopause; D016387:Women's Health