Determination of aliphatic alcohols after on-line microwave-assisted derivatization by liquid chromatography-photodiode array detection.
In this study, high-performance liquid chromatography (HPLC) in conjunction with continuous derivatization for the determination of aliphatic and polyethoxylated alcohol is reported. Reaction of alcohol group with phenyl isocyanate or benzyl chloride reagents assisted with microwaves (MW) irradiation is carried out in an on-line system coupled to HPLC with photodiode array detection (PDA). Reactor was placed into a microwave oven at 450W. The flow rate, reagent amounts, irradiation time, and chromatographic conditions were optimized. The continuous analysis using the system MW-HPLC-PDA provided high sensitivity, reduce the amount of reagents and analysis time. This proposed method can be used for the analysis of commercial alcohol polyethoxylated mixture.
Chávez
Gerson
G
Laboratorio de Petroquimica y Surfactantes, Departamento de Quimica, Facultad de Ciencias, La Universidad del Zulia, Maracaibo, P.O. Box Apartado Postal #15840, C.A. 4005 Zulia, Venezuela.
Bravo
Bélgica
B
Piña
Nolberto
N
Arias
Mónica
M
Vivas
Eliseo
E
Ysambertt
Fredy
F
Márquez
Nelson
N
Cáceres
Ana
A