title: Can duplex arterial ultrasonography reduce unnecessary angiography?
abstract: OBJECTIVE
  To assess the value of arterial duplex ultrasound, which assesses the location and severity of arterial disease, in determining whether invasive vascular intervention is required.
  
  
  METHODS
  A total of 166 consecutive diabetic patients presenting at a multidisciplinary foot clinic with severe peripheral vascular disease, with or without a foot ulcer, were included in this prospective study. The choice of vascular intervention was based on the results of a duplex ultrasound examination. Subjects were followed up for two years, and their clinical management, vascular assessments and interventions given, and patient outcomes were recorded in a specially designed protocol.
  
  
  RESULTS
  Based on findings of the duplex ultrasound, it was recommended that 55 patients (33%) should undergo angioplasty (percutaneous transluminal angioplasty [PTA] and/or subintimal recanalisation), 64 patients (39%) diagnostic angiography and 47 patients (28%) medical treatment only, thereby avoiding unnecessary angiography and its potential complications. Diagnostic angiography was recommended when the duplex ultrasound results were inconclusive. Fifty-two of the 55 patients recommended angiography with simultaneous angioplasty had an angiography; of these, 42 (81%) then had an angioplasty. Fifty-seven of the 64 patients with inconclusive results had an angiography. Of these, 23 (40%) subsequently had angioplasty, only 10 (18%) had reconstructive surgery and 24 (42%) had a diagnostic angiography only.
  
  
  CONCLUSIONS
  Arterial duplex ultrasound may assist evaluations of the need for and type of invasive vascular intervention in patients with an ischaemic diabetic foot. It can thus help avoid diagnostic angiographies that do not result in vascular intervention. However, such decision-making remains at the discretion of the vascular surgeon and radiologist.
authors.affiliation: Department of Clinical Science, Division of Diabetes and Endocrinology, all Malmö University Hospital, Lund University, Sweden. targ.elgzyri@med.lu.se
authors.forename: T
authors.initials: T
authors.lastname: Elgzyri
authors.forename: G
authors.initials: G
authors.lastname: Ekberg
authors.forename: K
authors.initials: K
authors.lastname: Peterson
authors.forename: A
authors.initials: A
authors.lastname: Lundell
authors.forename: J
authors.initials: J
authors.lastname: Apelqvist
mesh_terms: D000792:Angiography; D001158:Arteries / Q000000981:diagnostic imaging*; D003663:Decision Trees; D006801:Humans; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging*; D018608:Ultrasonography, Doppler