title: Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions.
abstract: Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue. In this paper, we report a multicentric GCT affecting a 41-year-old black woman, with nodules in perineum, groin, vulva, tongue and lip. Some of these lesions were surgically resected, but in a six-year follow-up, new primary lesions and recurrences were observed. In addition, the patient opted to do not remove some of these lesions, but there were not significant intercurrences. In view of the present findings, aspects related to clinical presentation, multiplicity, malignant potential, and treatment of GCT are discussed.
authors.affiliation: Department of Oral Pathology, School of Dentistry, Federal University of Uberlândia, Brazil.
authors.forename: Sergio
authors.initials: S
authors.lastname: Sargenti-Neto
authors.forename: Marco Túllio
authors.initials: MT
authors.lastname: Brazão-Silva
authors.forename: Kelen Christine
authors.initials: KC
authors.lastname: do Nascimento Souza
authors.forename: Paulo Rogério
authors.initials: PR
authors.lastname: de Faria
authors.forename: Antônio Francisco
authors.initials: AF
authors.lastname: Durighetto-Júnior
authors.forename: Adriano Mota
authors.initials: AM
authors.lastname: Loyola
authors.forename: Sérgio Vitorino
authors.initials: SV
authors.lastname: Cardoso
mesh_terms: D000328:Adult; D005260:Female; D005833:Genital Neoplasms, Female / Q000601:surgery; D016586:Granular Cell Tumor / Q000473:pathology*; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010502:Perineum / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology*; D014062:Tongue Neoplasms / Q000473:pathology*