title: [Is it safe to use josamycin in the obstetrics practice in Russia?].
abstract: The present situation with the use of antimicrobial drugs for the management of Chlamydia trachomatis infection during pregnancy in the Russian Federation was evaluated. The efficacy and safety of various macrolides in the treatment of chlamydial infection in practical obstetrics were analyzed. It was conclude that josamycin was inferior to azithromycin by a number of pharmacologic parameters, compliance and safety and therefore should not be used in pregnant women.
authors.forename: A A
authors.initials: AA
authors.lastname: Khrianin
authors.forename: O V
authors.initials: OV
authors.lastname: Reshetnikov
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000188:drug therapy*; D002692:Chlamydia trachomatis; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D015570:Josamycin / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D012426:Russia
chemical_list: D000900:Anti-Bacterial Agents; D015570:Josamycin