title: Off-pump coronary revascularization for left main coronary artery stenosis.
abstract: Experience of on- and off-pump coronary artery bypass in 379 patients with significant left main coronary artery stenosis was retrospectively reviewed. Beating-heart operations were performed on 219 patients between January 2001 and October 2007. Their results were compared with 160 who underwent revascularization under cardiopulmonary bypass during the same period. All patients had multivessel grafting via a median sternotomy. Both groups were comparable demographically. Off-pump patients received significantly fewer grafts per patient (3.21 +/- 0.86 vs 3.74 +/- 0.82). The use of moderate or high doses of inotropics (> 5 microg kg(-1) min(-1)) was more frequent in the on-pump group (44% vs 26%). Postoperative blood transfusion requirement was lower in off-pump patients, and fewer of them experienced worsening of preexisting renal insufficiency. There were 2 operative deaths in the on-pump group and 1 in the off-pump group. The off-pump procedure is safe and effective in patients with left main coronary artery disease.
authors.affiliation: Division of Cardiothoracic Surgery, CARE Hospital, The Institute of Medical Sciences, Hyderabad-500034, India.
authors.forename: Gopichand
authors.initials: G
authors.lastname: Mannam
authors.forename: Lokeswara R
authors.initials: LR
authors.lastname: Sajja
authors.forename: Satya B R
authors.initials: SB
authors.lastname: Dandu
authors.forename: Satyendra N
authors.initials: SN
authors.lastname: Pathuri
authors.forename: Krishnamurthy V S S
authors.initials: KV
authors.lastname: Saikiran
authors.forename: Sriramulu
authors.initials: S
authors.lastname: Sompalli
mesh_terms: D000368:Aged; D001803:Blood Transfusion; D002316:Cardiotonic Agents / Q000627:therapeutic use; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects / Q000401:mortality; D023921:Coronary Stenosis / Q000150:complications / Q000401:mortality / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D051437:Renal Insufficiency / Q000150:complications; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002316:Cardiotonic Agents