title: Flow-injection extraction-spectrophotometric determination of imipramine in pharmaceuticals with methyl orange.
abstract: Imipramine in aqueous solution is extracted into 1,2-dichloroethane as its ion-pair with Methyl Orange in an unsegmented flow system and quantified spectrophotometrically. A linear calibration graph was obtained between 0.79 and 25.3 mug/ml of imipramine. Up to 45 samples/hr can be processed with a RSD of 0.88-1.6%. The method was satisfactorily applied to the determination of imipramine in pharmaceutical preparations.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Pérez-Ruiz
authors.forename: C
authors.initials: C
authors.lastname: Martinez-Lozano
authors.forename: A
authors.initials: A
authors.lastname: Sanz
authors.forename: C
authors.initials: C
authors.lastname: Alonso