title: Lower gastrointestinal disorders in patients with irritable bowel syndrome.
abstract: Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal system characterized by abdominal pain related to bowel emptying, defecation impairment and abdominal distention. The aim of the study was to objectify lower gastrointestinal system disturbances in IBS patients. Thirty IBS patients and 30 healthy subjects were included in the study. IBS patients were divided into two subgroups: IBS with predominant diarrhea (IBSd) and IBS with predominant constipation (IBSc). All study subjects underwent physical examination (including digitorectal examination), standard laboratory testing and anorectal manometry. Endoscopy was performed only in group of IBS patients. A statistically significant difference was recorded in most manometric parameters between healthy subjects and IBS patients, which was even more pronounced in IBSd patients. Study results showed that the intestinal motility disorder underlying IBS could be objectified by use of anorectal manometry.
authors.affiliation: Department of Hepatogastroenterology, General Hospital "Sveti Duh", Zagreb, Croatia. dragan.jurcic@yahoo.com
authors.forename: Dragan
authors.initials: D
authors.lastname: Jurcić
authors.forename: Ante
authors.initials: A
authors.lastname: Bilić
authors.forename: Dragan
authors.initials: D
authors.lastname: Schwarz
authors.forename: Kresimir
authors.initials: K
authors.lastname: Luetic
authors.forename: Marinko
authors.initials: M
authors.lastname: Marusić
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Vcev
authors.forename: Maruska
authors.initials: M
authors.lastname: Gabrić
authors.forename: Ljubica
authors.initials: L
authors.lastname: Spoljarić
mesh_terms: D000328:Adult; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D005769:Gastrointestinal Motility; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000175:diagnosis*; D041741:Lower Gastrointestinal Tract; D008297:Male; D008365:Manometry