[Ocular motor disorders in multiple sclerosis].
Multiple sclerosis is the most common disabling neurological disease in young people. Many neuro-ophthalmological manifestations can occur during the course of the illness, and optic neuritis is both the most frequent and the best known. However, some ocular motility disorders can also occur, but since there may be no symptoms, they often remain underdiagnosed. These eye movement disorders are mostly related to brain-stem and cerebellum lesions. They can be acute, indicating a spatial dissemination of the demyelinating disease, and consequently may indicate the need for systemic treatment of multiple sclerosis. More often, they evolve slowly, progressing with the multiple sclerosis. In this case, they could provide a clue to the prognosis of the disease. In this survey, we discuss the two major symptoms of ocular motor disorders likely to occur during multiple sclerosis: oscillopsia and diplopia.
Rougier
M-B
MB
Unité Rétine-Uvéites-Neuro-ophtalmologie, Service d'Ophtalmologie, Hôpital Pellegrin - CHU de Bordeaux, Bordeaux, France. marie-benedicte.renaud-rougier@chu-bordeaux.fr
Tilikete
C
C
D001933:Brain Stem / Q000503:physiopathology; D002531:Cerebellum / Q000503:physiopathology; D004172:Diplopia / Q000209:etiology / Q000503:physiopathology; D018450:Disease Progression; D006801:Humans; D008636:Mesencephalon / Q000503:physiopathology; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology; D009759:Nystagmus, Pathologic / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D015835:Ocular Motility Disorders / Q000209:etiology* / Q000503:physiopathology; D009802:Oculomotor Nerve / Q000503:physiopathology; D011379:Prognosis; D012021:Reflex, Abnormal; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012438:Saccades / Q000502:physiology; D013028:Space Perception