Cytotoxic constituents ofSorbaria sorbifolia var.stellipila.
The acivity-guided fractionation upon the MeOH extract of the aerial parts ofSorbaria sorbifolia var.stellipila led to the isolation of two cucurbitacin-compounds, cucurbitacin D and cucurbitacin F, as active principles. Two compounds were shown to exhibit significant cytotoxicity against cultured human tumor cell lines, A-549, SK-OV-3, SK-MEL-2, XF-498, and HCT 15.
Kim
D K
DK
College of Pharmacy, Sung Kyun Kwan University, 440-746, Suwon, Korea.
Choi
S H
SH
Lee
J O
JO
Ryu
S Y
SY
Park
D K
DK
Shin
D H
DH
Jung
J H
JH
Pyo
S K
SK
Lee
K R
KR
Zee
O P
OP