Photometric and amperometric flow-injection determination of triazolam and clotiazepam.
Triazolam and clotiazepam can be determined by flow-injection analysis with photometric and amperometric detection. With photometric detection, the signals are a linear function of the drug concentration from 3 to 55muM (lambda = 228 nm) for triazolam and from 31 to 502muM (lambda = 390 nm) and from 6 to 125muM (lambda = 260 nm) for clotiazepam. FIA systems with amperometric detection allow the determination of these drugs in the range 6-116muM (triazolam) and 16-162muM (clotiazepam).
Alonso
R M
RM
Departamento de Química, Facultad de Ciencias, UPV, Apdo. 644, 48080 Bilbao, Spain.
Jimenez
R M
RM
Carvajal
A
A
Garcia
J
J
Vicente
F
F
Hernandez
L
L