title: Differential effects of sodium selenite and nano-Se on growth performance, tissue se distribution, and glutathione peroxidase activity of avian broiler.
abstract: The present research evaluated differential effects of sodium selenite and nano-Se on growth performance, tissue Se distribution, and glutathione peroxidase (GSH-Px) activity of avian broiler. Broilers were randomly segregated into 12 groups so that three replicates were available for each of the three treatments (T-1, T-2, and T-3) and control groups. The control groups were fed basal diets without Se addition. T-1, T-2, and T-3 were fed with diets containing 0.2 mg kg(-1) sodium selenite, 0.2 mg kg(-1) nano-Se, and 0.5 mg kg(-1) nano-Se, respectively. Compared with the control, Se supplementation remarkably improved daily weight gain and survival rate and decreased feed conversion ratio (P < 0.05). However, no significant difference was observed between T-1, T-2, and T-3. The tissue Se content was significantly higher (P < 0.05) in Se-supplemented groups than the control, and T-3 showed the highest. Furthermore, higher Se content was observed in liver, and there was a significant difference (P < 0.05) compared with that in muscle. As for serum and hepatic GSH-Px activities, Se supplementation remarkably improved GSH-Px activity (P < 0.05), and there was no significant difference (P > 0.05) between treatments (T-1, T-2, and T-3).
authors.affiliation: Food Quality & Safety Department, Key Laboratory of Food Safety of Zhejiang Province, Zhejiang Gongshang University, Hangzhou, China. wangyb@mail.zjgsu.edu.cn
authors.forename: Yanbo
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000818:Animals; D002645:Chickens / Q000254:growth & development* / Q000378:metabolism; D019587:Dietary Supplements; D005979:Glutathione Peroxidase / Q000187:drug effects / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000378:metabolism; D053758:Nanoparticles; D012643:Selenium / Q000032:analysis / Q000378:metabolism*; D018038:Sodium Selenite / Q000494:pharmacology*; D014018:Tissue Distribution; D015430:Weight Gain / Q000187:drug effects
chemical_list: D005979:Glutathione Peroxidase; D012643:Selenium; D018038:Sodium Selenite