title: Peroxidase-like activity on organic hydroperoxides of ion-exchange resins modified with metal-porphine analogues and analytical application for determination of linoleate hydroperoxide.
abstract: The ion-exchange resins modified with metal-porphyrins and -phthalocyanines (M-P(r)) have been found to exhibit a peroxidase (POD)-like activity on organic peroxides in a reaction wherein a quinoid dye is formed from phenol and 4-aminoantipyrine. Among them, Mn- and Co-P(r) exhibited stronger activity than hemoglobin and Fe-P(r), and hence were expected to be practically useful as a solid catalyst for the determination of linoleate hydroperoxide (LOOH). In addition, a resin modified with Co(3+)-phthalocyanine tetrasulfonate (Co-PCS(r)) lacks POD-like activity on hydrogen peroxide in contrast with Mn-P(r). We, therefore, concluded that Co-PCS(r) is superior to both Mn-P(r) and hemoglobin as a solid catalyst on organic hydroperoxides, and developed a new method for the determination of LOOH.
authors.affiliation: Faculty of Pharmaceutical Sciences, Okayama University, Tsushima-Naka, Okayama 700-8530, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Mifune
authors.forename: T A
authors.initials: TA
authors.lastname: Tai
authors.forename: A
authors.initials: A
authors.lastname: Iwado
authors.forename: H
authors.initials: H
authors.lastname: Akizawa
authors.forename: J
authors.initials: J
authors.lastname: Oda
authors.forename: N
authors.initials: N
authors.lastname: Motohashi
authors.forename: Y
authors.initials: Y
authors.lastname: Saito