title: Patient with obstructive sleep apnea-hypopnea syndrome and SCN5A mutation (R1193Q polymorphism) associated with Brugada type 2 electrocardiographic pattern.
abstract: We describe a 45-year-old Asian man with Brugada-type 2 electrocardiogram and probable nocturnal agonal respiration. After genetic screening, drug challenge test and polysomnography examination, we ruled out Brugada syndrome and identified obstructive sleep apnea-hypopnea syndrome. Therefore, obstructive sleep apnea-hypopnea syndrome should be considered as a rare differential diagnosis for Brugada syndrome.
authors.affiliation: Heart Center, Peking University People's Hospital, Beijing, PR China.
authors.forename: Xiaoliang
authors.initials: X
authors.lastname: Qiu
authors.forename: Wenling
authors.initials: W
authors.lastname: Liu
authors.forename: Dayi
authors.initials: D
authors.lastname: Hu
authors.forename: Yihong
authors.initials: Y
authors.lastname: Sun
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.forename: Cuilan
authors.initials: C
authors.lastname: Li
mesh_terms: D053840:Brugada Syndrome / Q000150:complications / Q000175:diagnosis* / Q000235:genetics*; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000379:methods*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000175:diagnosis* / Q000235:genetics*