Low frequency of GB virus C viremia in a cohort of HIV-1-infected elite suppressors.
The persistence of GB virus C viremia in patients with chronic HIV-1 infection has been associated with increased survival. Elite suppressors are untreated HIV-1-infected patients who maintain viral loads of below 50 copies/ml. This study found that the frequency of GB virus C viremia in elite suppressors and chronically infected patients with progressive disease was not significantly different. Thus, GB virus C does not appear to explain the nonprogressive course seen in this cohort of elite suppressors.
Blankson
Joel N
JN
Department of Medicine, John Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. jblanks@jhmi.edu
Klinzman
Donna
D
Astemborski
Jacquie
J
Thomas
David L
DL
Kirk
Gregory D
GD
Stapleton
Jack T
JT
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000821:virology; D000818:Animals; D018791:CD4 Lymphocyte Count; D018178:Flaviviridae Infections / Q000188:drug therapy; D029407:GB virus C / Q000235:genetics / Q000302:isolation & purification; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1 / Q000235:genetics*; D006525:Hepatitis, Viral, Human / Q000188:drug therapy; D006801:Humans; D019562:Viral Load; D014766:Viremia / Q000150:complications / Q000188:drug therapy