title: FIA titrations of phenothiazine derivatives in aqueous micellar and non-aqueous media.
abstract: New methods of flow injection analysis (FIA) neutralization titrations of phenothiazine derivatives in aqueous micellar medium of a cationic surfactant using potentiometric and spectrophotometric detection were proposed; titrations with a mixing gradient chamber and high-speed titrations were compared. The FIA titration method in non-aqueous media based on an official method of determination (titration with perchloric acid in anhydrous acetic acid) was also developed. Under optimized reaction conditions and flow-through parameters, the calibration range and equations, the sensitivity, and the repeatability of all methods were found and discussed. All titrations were assayed for medicinal forms.
authors.affiliation: Department of Analytical Chemistry, Faculty of Science, Charles University of Prague, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
authors.forename: Irena
authors.initials: I
authors.lastname: Nemcová
authors.forename: Karel
authors.initials: K
authors.lastname: Nesmerák
authors.forename: Petr
authors.initials: P
authors.lastname: Rychlovský
authors.forename: Jitka
authors.initials: J
authors.lastname: Koutníková