title: Acid-base equilibria and assay of benzodiazepines in acetonitrile medium.
abstract: The acid-base equilibria of a series of benzodiazepines in acetonitrile have been studied, and pK(HB+) values determined. The theory of such titrations is discussed and simple potentiometric and visual methods in acetonitrile media are proposed for the assay of benzodiazepines in pharmaceutical formulations.
authors.affiliation: Department de Química Analítica, Universitat de Barcelona, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Barbosa
authors.forename: V
authors.initials: V
authors.lastname: Sanz-Nebot