[Applications and progresses of liquid chromatography-mass spectrometry in doping control].
High performance liquid chromatography-mass spectrometry (LC-MS) has enabled the determination of most of the prohibited drugs in doping analysis, including many small molecular doping agents and peptide hormones. This paper reviews liquid chromatography-mass spectrometry for the screening, identification and quantification of doping agents in urine and other biological samples. Criteria for the identification of compounds by LC-MS are also discussed.
Qin
Yang
Y
China Anti-Doping Agency, Beijing 100029, China. qinyang@chinada.cn
Xu
Youxuan
Y
Yang
Shumin
S
Zhu
Shaotang
S
D002853:Chromatography, Liquid / Q000379:methods* / Q000592:standards; D004300:Doping in Sports; D006801:Humans; D007390:International Agencies / Q000592:standards; D013058:Mass Spectrometry / Q000379:methods* / Q000592:standards; D015813:Substance Abuse Detection / Q000379:methods* / Q000592:standards