Exploiting sequential injection analysis with lab-at-valve (LAV) approach for on-line liquid-liquid micro-extraction spectrophotometry.
Sequential injection analysis (SIA) with lab-at-valve (LAV) approach for on-line liquid-liquid micro-extraction has been exploited. Sample, reagent and organic solvent were sequentially aspirated into a coil attached to a central port of a conventional multiposition selection valve, where the extraction process was performed. The aqueous and organic phases were separated in a conical separating chamber LAV unit attached at one port of the valve. The organic phase containing extracted product was then monitored spectrophotometrically. The system offers a novel alternative on-line automated extraction in a micro-scale and has been successfully demonstrated for the assays of diphenhydramine hydrochloride (DPHH) in pharmaceutical preparations and anionic surfactant in water samples.
Burakham
Rodjana
R
Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Lapanantnoppakhun
Somchai
S
Jakmunee
Jaroon
J
Grudpan
Kate
K