Urinary symptoms and impact on quality of life in women after treatment for endometrial cancer.
The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment for endometrial cancer. Three validated questionnaires were utilized: the Sandvik Severity Index, the Urinary Distress Inventory-6 (UDI-6), and Incontinence Impact Questionaire-7 (IIQ-7). Our study included 70 women treated for endometrial cancer; 35.7% (25/70) of women reported adjuvant radiation therapy after surgical staging. Urinary incontinence was reported in over 80% of women. Mean UDI-6 and IIQ-7 scores for women treated with adjuvant radiation therapy were higher compared to women with no adjuvant radiation therapy [47(+/-26.8) vs. 35.6(+/-21.7; p = 0.05)] and [24.4(+/-28.5) vs. 8.1(+/-16.4; p = 0.004)], respectively. Treatment with adjuvant radiation therapy was associated with more severe incontinence symptoms and impact on quality of life.
Erekson
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Division of Urogynecology and Pelvic Reconstructive Surgery, Alpert Medical School at Brown University, Women and Infants' Hospital of Rhode Island, 695 Eddy St, Ste. 12, Providence, RI 02903, USA. EErekson@wihri.org
Sung
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VW
DiSilvestro
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Myers
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D000368:Aged; D003430:Cross-Sectional Studies; D016889:Endometrial Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006306:Health Surveys; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life / Q000523:psychology; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000209:etiology* / Q000523:psychology