title: [Effects of bagasse polysaccharide on the immune functions of immunosuppressed mice].
abstract: OBJECTIVE
  To observe the effects of bagasse polysaccharide on the immune functions of immunosuppressed mice.
  
  
  METHODS
  Immunosuppressed mouse models were established by intraperitoneal injections with cyclophosphamide followed by daily intragastric administration of bagasse polysaccharide. After the treatments, the mice were examined for immune organ weight index, phagocytotic function of the macrophages, delayed type hypersensitivity, serum IgM level following exposure to chicken red blood cells, formation of hemolytic plaques, T cell percentage and lymphocyte transformation.
  
  
  RESULTS
  Treatment of the immunosuppressed mice with bagasse polysaccharide at the daily dose of 200 and 400 mg/kg significantly increased the weight of the immune organs, phagocytotic function of the macrophages, delayed type hypersensitivity, serum IgM level against chicken red blood cells, formation of hemolytic plaques, T cell percentage and lymphocyte transformation.
  
  
  CONCLUSIONS
  Bagasse polysaccharide can enhance the immune functions of immunosuppressed mice.
authors.affiliation: Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.forename: Yu-hong
authors.initials: YH
authors.lastname: Song
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Cai
authors.forename: Xue-gang
authors.initials: XG
authors.lastname: Sun
authors.forename: Zhi-liang
authors.initials: ZL
authors.lastname: Chen
mesh_terms: D000818:Animals; D002482:Cellulose / Q000737:chemistry*; D003520:Cyclophosphamide; D005260:Female; D016867:Immunocompromised Host / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D011134:Polysaccharides / Q000494:pharmacology*; D011897:Random Allocation
chemical_list: D011134:Polysaccharides; D003520:Cyclophosphamide; D002482:Cellulose; C027433:bagasse