title: Anterior cervical fusion using a polyetheretherketone cage containing a bovine xenograftp: three to five-year follow-up.
abstract: METHODS
  Retrospective review of an anterior polyetheretherketone (PEEK) cage incorporated with a bovine xenograft to treat disorders of the cervical disc.
  
  
  OBJECTIVE
  To assess the achievement of fusion by PEEK cage with xenograft radiographically and clinically when used to perform ACDF.
  
  
  BACKGROUND
  Anterior cervical discectomy and fusion is the therapy of choice for degenerative disc disorders of the cervical spine. Although cage device increases initial stability of the levels treated, fusion is the key factor for satisfactory results. Filling the cage devices with autologous iliac bone grafts enable achievement of the best fusion result. Although the volume of harvested bone graft is minimal, donor-site morbidity is still a complication of concern. To avoid this adverse issue, we used a new bovine xenograft in place of autologous bone graft.
  
  
  METHODS
  Fifty-six patients (33 men and 23 women aged 31-78 years) underwent anterior cervical discectomy and fusion using PEEK cage with a bovine xenograft bone substitute to treat symptomatic cervical disorders. Radiographic and clinical results were assessed over 3 to 5 years of follow up.
  
  
  RESULTS
  Almost all patients had symptomatic improvement, and 84% reported good-to-excellent satisfaction. All cases achieved solid fusion, confirmed by radiographs and computed tomography, but cage subsidence occurred at 8 levels.
  
  
  CONCLUSIONS
  As applied in anterior cervical fusion, the cage incorporated with the xenograft prevented donor-site morbidity and provided successful fusion.
authors.affiliation: Department of Orthopedic Surgery, Taipei City Hospital, Taipei, Taiwan.
authors.forename: Chang-Jung
authors.initials: CJ
authors.lastname: Chiang
authors.forename: Yi-Jie
authors.initials: YJ
authors.lastname: Kuo
authors.forename: Yueh-Feng
authors.initials: YF
authors.lastname: Chiang
authors.forename: Gary
authors.initials: G
authors.lastname: Rau
authors.forename: Yang-Hwei
authors.initials: YH
authors.lastname: Tsuang
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001577:Benzophenones; D016025:Bone Transplantation; D002417:Cattle; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D017586:Diskectomy / Q000295:instrumentation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016268:Internal Fixators; D007659:Ketones; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D017060:Patient Satisfaction; D011092:Polyethylene Glycols; D011108:Polymers; D011859:Radiography; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods; D014183:Transplantation, Heterologous; D016896:Treatment Outcome
chemical_list: D001577:Benzophenones; D007659:Ketones; D011108:Polymers; C063834:polyetheretherketone; D011092:Polyethylene Glycols