Micro- and nanofluidic systems for high-throughput biological screening.
High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.
Hong
Jongin
J
Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom.
Edel
Joshua B
JB
deMello
Andrew J
AJ
D000818:Animals; D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004345:Drug Industry / Q000379:methods; D006801:Humans; D046228:Microarray Analysis / Q000379:methods; D044085:Microfluidics / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*