Use of p-chloranilic acid for the colorimetric determination of some antimalarials.
A simple and sensitive colorimetric method for the assay of quinine sulphate, primaquine diphosphate, amodiaquine hydrochloride and pyrimethamine is described. The method is based on the interaction of the drugs and p-chloranilic acid to give a stable product with an intense colour which can be used for the determination of these antimalarials in their pharmaceutical preparations.
Mahrous
M S
MS
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt.
Salam
M A
MA
Issa
A S
AS
Abdel-Hamid
M
M