[A case-control study of the risk factors for fungal rhinosinusitis].
OBJECTIVE
To investigate the risk factors of fungal rhinosinusitis.


METHODS
The preoperative clinical data of 57 patients with a diagnosis of fungal rhinosinusitis confirmed pathologically using Gomori methenamine silver staining were analyzed statistically against the data of 57 age- and gender-matched control patients with chronic rhinosinusitis.


RESULTS
Compared with chronic rhinosinusitis, fungal rhinosinusitis was characterized by a significantly shorter mean disease course (37.31 months vs 130.84 months, t = 5.59, P = 0.000). The factors related to fungal rhinosinusitis included nasal mucus, purulent nasal discharge, unilateral/bilateral sinus lesion and calcified plaque in CT scan , with odds ratios of 0.17 (0.04-0.62), 0.35 (0.15-0.80), 41 (12.50-100.00) and 91 (24.01-344.95), respectively. Conditional logistic regression identified calcified plaque in CT scan as the high-risk factor of fungal rhinosinusitis.


CONCLUSIONS
The presence of calcified plaque in CT scan indicates high risk of fungal rhinosinusitis and may serve as an important evidence for diagnosis of this disease.
Zeng
Zhuan-ping
ZP
Department of Epidemiology, College of Public Health, Guangdong Pharmaceutical University, Guangzhou 510315, China. joycezzp@163.com
Liao
Ri-fang
RF
Zhang
Ge-hua
GH
D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D005658:Fungi; D006801:Humans; D008297:Male; D009181:Mycoses / Q000453:epidemiology; D012220:Rhinitis / Q000453:epidemiology / Q000382:microbiology*; D012307:Risk Factors; D012852:Sinusitis / Q000453:epidemiology / Q000382:microbiology*