[A rapid capillary zone electrophoresis method for simultaneous determination of several kinds of doping agents].
A capillary zone electrophoresis-ultraviolet detection (CZE-UV) method was established for the simultaneous determination of eight doping agents which belong to diuretics, anabolic steroids, beta-blocks, narcotics, beta2-agonists and stimulants. Under the optimal conditions, with 50 mmol/L ammonium formate buffer (pH 7.8) as the running buffer, injection at a pressure of 3 kPa for 10 s, applied voltage of 20 kV, and detection at 214 nm, eight doping agents were separated quickly and completely within 7 min. The linearities of the eight doping anents were good in respective concentration ranges. Their detection limits were from 0.2 to 0.7 microg/mL. It is a simple and rapid method with small sample size for doping detection.
Xiao
Hui
H
Key Laboratory of Analysis and Detection for Food Safety, Ministry of Education Sport Science Research Center, Fuzhou University, Fuzhou 350002, China. nowmaggyis@126.com
Tong
Ping
P
Feng
Qiang
Q
Zhang
Lan
L
D002021:Buffers; D002138:Calibration; D004300:Doping in Sports; D019075:Electrophoresis, Capillary / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D016014:Linear Models; D015813:Substance Abuse Detection / Q000379:methods*; D013997:Time Factors
D002021:Buffers