Some spectrophotometric methods for determination of certain antipyretic and antirheumatic drugs.
Heating paracetamol in strongly alkaline medium with 4-nitrosoantipyrine gives a red colour with maximum absorption at 515 nm. Mefenamic and flufenamic acids can be determined colorimetrically after extraction as ion-pairs with Methylene Blue.
Issa
A S
AS
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Beltagy
Y A
YA
Gabr Kassem
M
M
Daabees
H G
HG