Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men.
In this randomized, placebo-controlled, double-blind study of 57 abdominally obese middle-aged men, conjugated linoleic acid (CLA) did not induce changes in retinol-binding protein 4 concentrations (RBP4), despite marked induced insulin resistance. Further, there were no associations between CLA-induced insulin resistance and changes in RBP4.
Ingelsson
Erik
E
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. erik.ingelsson@ki.se
Risérus
Ulf
U
D050153:Abdominal Fat; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D006801:Humans; D007333:Insulin Resistance; D044243:Linoleic Acids, Conjugated / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy*; D054839:Retinol-Binding Proteins, Plasma / Q000032:analysis / Q000187:drug effects*
D044243:Linoleic Acids, Conjugated; C101326:RBP4 protein, human; D054839:Retinol-Binding Proteins, Plasma