[Secondary metabolites of a marine mangrove fungus (Penicillium sp. no. 2556) from South China Sea].
The metabolites of a marine mangrove fungus (Penicillium sp. No. 2556) were studied in this paper and six compounds were isolated from the fermentation liquid. Their structures were elucidated by spectroscopy methods as Sch54796 (1), Sch54794 (2), 4-hydroxybenzoic acid (3), urail (4), succinic acid (5), Vermopyrone (6). Among them, compounds 1, 2 and 6 were firstly isolated from Penicillium sp., Coumpounds 1 and 2 remarkably inhibited the growth of cancer cell lines hep2 and hepG2.
Li
Chun-Yuan
CY
Department of Applied Chemistry, College of Sciences, South China Agricultural University, Guangzhou 510642, China. chunyuanli@scau.edu.cn
Ding
Wei-Jia
WJ
Shao
Chang-Lun
CL
She
Zhi-Gang
ZG
Lin
Yong-Cheng
YC
D000970:Antineoplastic Agents / Q000494:pharmacology; D045744:Cell Line, Tumor; D002681:China; D047169:Cyclotides / Q000737:chemistry / Q000302:isolation & purification*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010226:Parabens / Q000737:chemistry / Q000302:isolation & purification*; D010407:Penicillium / Q000737:chemistry* / Q000378:metabolism; D043982:Rhizophoraceae / Q000382:microbiology*; D017550:Spectroscopy, Fourier Transform Infrared; D019802:Succinic Acid / Q000737:chemistry / Q000302:isolation & purification
D000970:Antineoplastic Agents; D047169:Cyclotides; D010226:Parabens; D019802:Succinic Acid; C038193:4-hydroxybenzoic acid