A solid-phase spectrophotometric method for the determination of sulphathiazole.
A spectrophotometric method for the determination of sulphathiazole (ST) has been developed, based on solid-phase spectrophotometry. The influence of experimental variables on fixation on Sephadex SP C-25 is discussed. The applicable concentration range is 0.10-10.00 mg/l., with a relative standard deviation of 0.62% and a detection limit of 0.02 mg/l. The accuracy and precision of the method are reported. The proposed method has been satisfactorily applied to the determination of sulphathiazole in pharmaceuticals.
Capitán-Vallvey
L F
LF
Department of Analytical Chemistry. University of Granada, Granada, Spain.
de Orbe
I
I
Valencia
M C
MC
Berzas-Nevado
J J
JJ