title: Rapid and simultaneous analysis of dichlorvos, malathion, carbaryl, and 2,4-dichlorophenoxy acetic acid in citrus fruit by flow-injection ion spray ionization tandem mass spectrometry.
abstract: A simple method for the rapid and simultaneous analysis of dichlorvos (DDVP), malathion, carbaryl, and 2,4-dichlorophenoxy acetic acid (2,4-D) in citrus fruit, which uses flow-injection ion spray ionization tandem mass spectrometry, has been developed for the first time. The method involves the combined use of stable isotopically labeled internal standards (DDVP-d(6), malathion-d(10), carbaryl-d(7), and 2,4-D-d(5)) and a multiple reaction monitoring technique. The average recoveries for the pesticides at the same concentrations as their tolerance levels (DDVP: 0.1-0.2mugg(-1); malathion: 0.5-4.0mugg(-1); carbaryl: 1.0mugg(-1); 2,4-D: 1.0-2.0mugg(-1)) ranged from 90 to 119% with the relative standard deviation (R.S.D.) ranging from 1.0 to 13.1% (n = 5). Analysis time, including sample preparation and determination, was only 15min. The present method is effective for screening DDVP, malathion, carbaryl, and 2,4-D in citrus fruit.
authors.affiliation: Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Koichi
authors.initials: K
authors.lastname: Inoue
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ito
authors.forename: Tomomi
authors.initials: T
authors.lastname: Goto
authors.forename: Kayoko
authors.initials: K
authors.lastname: Kato
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Yoshimura
authors.forename: Hisao
authors.initials: H
authors.lastname: Oka