title: BMI compared with central obesity indicators as a predictor of diabetes incidence in Mauritius.
abstract: The aim of the study was to compare BMI with waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-stature ratio (WSR) as a predictor of diabetes incidence. A total of 1,841 men and 2,104 women of Mauritian Indian and Mauritian Creole ethnicity, aged 25-74 years, free of diabetes, hypertension, cardiovascular disease, and gout were seen at baseline in 1987 or 1992, and follow-up in 1992 and/or 1998. At all time points, participants underwent a 2 h 75 g oral glucose tolerance test. Hazard ratios for diabetes incidence were estimated applying an interval-censored survival analysis using age as timescale. Six hundred and twenty-eight individuals developed diabetes during the follow-up period. Multivariable adjusted hazard ratios for diabetes incidence corresponding to a 1 s.d. increase in baseline BMI, WC, WHR, and WSR for Mauritian Indians were 1.49 (1.31-1.71), 1.58 (1.38-1.81), 1.54 (1.37-1.72), and 1.61 (1.41-1.84) in men and 1.33 (1.17-1.51), 1.35 (1.19-1.53), 1.39 (1.24-1.55), and 1.38 (1.21-1.57) in women, respectively; and for Mauritian Creoles they were 1.86 (1.51-2.30), 2.07 (1.68-2.56), 1.92 (1.62-2.26), and 2.17 (1.76-2.69) in men and 1.29 (1.06-1.55), 1.27 (1.04-1.55), 1.24 (1.04-1.48), and 1.27 (1.04-1.55) in women. Paired homogeneity tests showed that there was no difference between BMI and each of the central obesity indicators (all P > 0.05). The relation of BMI with the development of diabetes was as strong as that for indicators of central obesity in this study population.
authors.affiliation: Department of Public Health, University of Helsinki, Helsinki, Finland. regzedmaa.nyamdorj@helsinki.fi
authors.forename: Regzedmaa
authors.initials: R
authors.lastname: Nyamdorj
authors.forename: Qing
authors.initials: Q
authors.lastname: Qiao
authors.forename: Stefan
authors.initials: S
authors.lastname: Söderberg
authors.forename: Janne M
authors.initials: JM
authors.lastname: Pitkäniemi
authors.forename: Paul Z
authors.initials: PZ
authors.lastname: Zimmet
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Shaw
authors.forename: K G M M
authors.initials: KG
authors.lastname: Alberti
authors.forename: Vassen K
authors.initials: VK
authors.lastname: Pauvaday
authors.forename: Pierrot
authors.initials: P
authors.lastname: Chitson
authors.forename: Sudhirsen
authors.initials: S
authors.lastname: Kowlessur
authors.forename: Jaakko
authors.initials: J
authors.lastname: Tuomilehto
mesh_terms: D000328:Adult; D000368:Aged; D050218:Body Fat Distribution; D001827:Body Height / Q000502:physiology*; D015992:Body Mass Index; D003625:Data Collection; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008436:Mauritius / Q000453:epidemiology; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000208:ethnology / Q000503:physiopathology*; D016017:Odds Ratio; D011237:Predictive Value of Tests; D055105:Waist Circumference / Q000502:physiology*; D049629:Waist-Hip Ratio