Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals.
Among 177 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates collected from 11 Slovenian hospitals in 2005 and 2006, 60 (34%), from eight hospitals, harbored genes for CTX-M enzymes, with bla(CTX-M-15) detected by sequencing. These 60 isolates comprised 11 pulsed-field gel electrophoresis-defined strains, with several clusters of closely related isolates. Plasmids encoding CTX-M-15 enzyme were highly transmissible.
Mesko Meglic
K
K
Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia. karmen.mesko@mf.uni-lj.si
Koren
S
S
Palepou
M F I
MF
Karisik
E
E
Livermore
D M
DM
Pike
R
R
Andlovic
A
A
Jeverica
S
S
Krizan-Hergouth
V
V
Müller-Premru
M
M
Seme
K
K
Woodford
N
N
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016521:Electrophoresis, Gel, Pulsed-Field; D005798:Genes, Bacterial / Q000235:genetics / Q000502:physiology; D006761:Hospitals; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D017524:Slovenia; D001618:beta-Lactamases / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases