New phenylpropanoid esters of sucrose from Polygonum hydropiper and their antioxidant activity.
By various chromatographic methods, two new phenylpropanoid esters of sucrose named hidropiperosides A (1) and B (2), and three known compounds as vanicosides A (3), B (4), and E (5) were isolated from the methanolic extract of the whole plant of Polygonum hydropiper L. (Polygonaceae). Their structures were elucidated by extensive spectroscopic methods including 1D-and 2D-NMR experiments, as well as ESI-MS analysis. All the isolated compounds were tested for their antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay system. Among them, compounds 2 and 3 showed significant antioxidant activity with their SC(50) values of 23.4 and 26.7 microg/mL, respectively.
Kiem
Phan Van
PV
Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Nghiado, Caugiay, Hanoi, Vietnam.
Nhiem
Nguyen Xuan
NX
Cuong
Nguyen Xuan
NX
Hoa
Tran Quynh
TQ
Huong
Hoang Thanh
HT
Huong
Le Mai
le M
Minh
Chau Van
CV
Kim
Young Ho
YH
D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001713:Biphenyl Compounds; D002855:Chromatography, Thin Layer; D003373:Coumaric Acids / Q000302:isolation & purification / Q000494:pharmacology*; D004187:Disaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013395:Sucrose / Q000737:chemistry*
D000975:Antioxidants; D001713:Biphenyl Compounds; D003373:Coumaric Acids; D004187:Disaccharides; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; C534005:hidropiperoside B; D013395:Sucrose; C004931:1,1-diphenyl-2-picrylhydrazyl