title: Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders.
authors.affiliation: Department of Chemistry, Yale University, P. O. Box 208017, New Haven, CT 06520-8107, USA.
authors.forename: Patrick T
authors.initials: PT
authors.lastname: Gunning
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Glenn
authors.forename: Khandaker A Z
authors.initials: KA
authors.lastname: Siddiquee
authors.forename: William P
authors.initials: WP
authors.lastname: Katt
authors.forename: Eric
authors.initials: E
authors.lastname: Masson
authors.forename: Saïd M
authors.initials: SM
authors.lastname: Sebti
authors.forename: James
authors.initials: J
authors.lastname: Turkson
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Hamilton
mesh_terms: D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D008024:Ligands; D051379:Mice; D008958:Models, Molecular; D041681:NIH 3T3 Cells; D011485:Protein Binding; D055503:Protein Multimerization / Q000187:drug effects; D050796:STAT3 Transcription Factor / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D054852:Small Molecule Libraries / Q000737:chemistry* / Q000494:pharmacology; D018909:src Homology Domains
chemical_list: D008024:Ligands; D050796:STAT3 Transcription Factor; D054852:Small Molecule Libraries