Gastroesophageal regurgitation during anesthesia and controlled ventilation with six airway devices.
OBJECTIVE
To investigate the frequency of gastroesophageal regurgitation and respiratory mechanics during positive pressure ventilation using 5 supraglottic devices or an endotracheal tube (ETT).


METHODS
Prospective, randomized study.


METHODS
Operating rooms in a university-affiliated hospital.


METHODS
180 ASA physical status I and II patients, aged 18 to 65 years old, who underwent elective orthopedic, minor vascular, peripheral plastic, or urologic surgery during general anesthesia.


METHODS
Patients were randomly allocated to one of 6 airway device groups (n = 30 each): (1) Cobra Perilaryngeal Airway; (2) Laryngeal Mask Airway (LMA) Classic; (3) LMA Fastrach; (4) LMA ProSeal; (5) laryngeal tube; and (6) ETT (SIMS Portex, Ltd, Hythe, Kent, UK). After insertion of the designated device, the lungs of each nonparalyzed patient were mechanically ventilated.


METHODS
Hypopharyngeal pH, peak inspiratory pressures, sealing pressures, and lung compliance were measured. Hypopharyngeal pH lower than 4 was considered a regurgitation event.


RESULTS
Regurgitation (episodes of pH <4) occurred in between one and 5 patients of each study group, with no statistical difference. Sealing pressures were similar among all the airway device groups.


CONCLUSIONS
The frequency of gastroesophageal regurgitation in anesthetized, unparalyzed, mechanically ventilated patients was similar in patients whose lungs were ventilated with either the Cobra Perilaryngeal Airway, LMA Classic, Fastrach, ProSeal, laryngeal tube, or ETT.
Khazin
Vadim
V
Department of Anesthesia, The E. Wolfson Medical Center, Holon, Israel.
Ezri
Tiberiu
T
Yishai
Ron
R
Sessler
Daniel I
DI
Serour
Francis
F
Szmuk
Peter
P
Evron
Shmuel
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D017214:Laryngeal Masks; D008297:Male; D008875:Middle Aged; D011175:Positive-Pressure Respiration; D011446:Prospective Studies; D012107:Research Design; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult