title: Cutaneous angiosarcoma in a patient with xeroderma pigmentosum.
abstract: Xeroderma pigmentosum (XP) is a rare, autosomal recessive disorder characterized by photosensitivity, cutaneous pigmentary changes, premature skin ageing and development of various cutaneous and internal malignancies at an early age as a result of a defect in nucleotide excision repair following ultraviolet light exposure. Cutaneous angiosarcomas are aggressive neoplasms that are rarely associated with XP. In this communication, we report the case of a 40-year-old male patient with XP who developed an angiosarcoma of the face and discuss the implications of this association in view of recent developments in this field.
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi 110 029, India.
authors.forename: Raman
authors.initials: R
authors.lastname: Arora
authors.forename: Alok
authors.initials: A
authors.lastname: Sharma
authors.forename: Ruchika
authors.initials: R
authors.lastname: Gupta
authors.forename: M
authors.initials: M
authors.lastname: Vijayaraghavan
mesh_terms: D000328:Adult; D006394:Hemangiosarcoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D014983:Xeroderma Pigmentosum / Q000150:complications* / Q000473:pathology