Neurolological disorders and neuroprotection after heart surgery.
Neurological/neuropsychiatric complications are commonly observed after heart surgery. They include the cerebral ischemic episode, transient ischemic attack, postoperative cognitive decline and postoperative delirium. In this review article, we are dealing with the etiology of these complications, mainly focusing on the role of genetic com-ponents. We are also commenting on the putative role of certain pharmacologic agents in the treatment of the aforementioned nosological entities.
Tagarakis
Georgios I
GI
Cardiothoracic Department, University Hospital of Larissa, Greece. gtagarakis@hotmail.com
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000188:drug therapy* / Q000209:etiology / Q000235:genetics; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003072:Cognition Disorders / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D011110:Polymorphism, Genetic; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D018696:Neuroprotective Agents; D017367:Selective Serotonin Reuptake Inhibitors