title: Biologically relevant chemical properties of peroxymonophosphate (=O3POOH).
abstract: It has been suggested that peroxymonophosphate could serve as an endogenous hydrogen peroxide-derived regulator of cellular protein tyrosine phosphatase activity under physiological or pathophysiological conditions. To facilitate further consideration of the potential role of peroxymonophosphate in biological systems we present studies related to the preparation, characterization, stability, and fluorometric detection of this agent.
authors.affiliation: Departments of Chemistry and Biochemistry, University of Missouri, 125 Chemistry Building, Columbia, MO 65211, USA.
authors.forename: Jason N
authors.initials: JN
authors.lastname: LaButti
authors.forename: Kent S
authors.initials: KS
authors.lastname: Gates
mesh_terms: D000818:Animals; D004355:Drug Stability; D006861:Hydrogen Peroxide; D010710:Phosphates / Q000032:analysis / Q000138:chemical synthesis / Q000494:pharmacology; D017027:Protein Tyrosine Phosphatases / Q000187:drug effects*
chemical_list: D010710:Phosphates; C521235:peroxymonophosphate; D006861:Hydrogen Peroxide; D017027:Protein Tyrosine Phosphatases