title: Unfaithful association of FCGR2B genetic polymorphisms with susceptibility to SLE.
abstract: Correcting errors and proofreading are crucial in a post-genomic era, when DNA sequences are already part of an effective medical screening and treatments. SNPs genotyping of complex human genes can lead to questionable associations if not properly handled. Here, we report about a spurious (reitered) association between FCGR2B genetic polymorphisms and systemic lupus erythematosus.
authors.affiliation: Department of Biology MCA, University of Camerino, Camerino, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Napolioni
authors.forename: Alessandra
authors.initials: A
authors.lastname: Barucca
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Bolli
authors.forename: Antonio
authors.initials: A
authors.lastname: Concetti
authors.forename: Franco Maria
authors.initials: FM
authors.lastname: Venanzi
mesh_terms: D001483:Base Sequence; D002681:China / Q000453:epidemiology; D005190:Family; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000453:epidemiology / Q000235:genetics*; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide; D017452:Receptors, IgG / Q000235:genetics*
chemical_list: C499173:FCGR2B protein, human; D017452:Receptors, IgG