title: Severe hyperbilirubinemia in a glucose-6-phosphate dehydrogenase-deficient preterm neonate: could prematurity be the main responsible factor?
abstract: We report on a premature infant with glucose-6-phosphate dehydrogenase deficiency and severe hyperbilirubinemia. In this patient, all known potential hemolytic agents were excluded and no findings of hemolysis were observed. The crucial role of prematurity in the pathogenesis of this type of jaundice is discussed.
authors.affiliation: Division of Neonatology, Department of Pediatrics, University Hospital Agostino Gemelli, Catholic University of the Sacred Heart, Rome, Italy. imocosta@yahoo.it
authors.forename: Simonetta
authors.initials: S
authors.lastname: Costa
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: De Carolis
authors.forename: Daniele
authors.initials: D
authors.lastname: De Luca
authors.forename: Immacolata
authors.initials: I
authors.lastname: Savarese
authors.forename: Costantino
authors.initials: C
authors.lastname: Romagnoli
mesh_terms: D000328:Adult; D000745:Anemia, Hemolytic, Congenital / Q000209:etiology / Q000235:genetics / Q000378:metabolism; D001663:Bilirubin / Q000097:blood; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000235:genetics* / Q000378:metabolism; D006400:Hematocrit; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000209:etiology* / Q000235:genetics* / Q000378:metabolism; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011247:Pregnancy; D012720:Severity of Illness Index; D014310:Triplets
chemical_list: D001663:Bilirubin