title: Is Escherichia coli O157:H7 a common pathogen in children with bloody diarrhea in Shiraz, Iran?
abstract: Escherichia coli (E. coli) O157:H7 is a common cause of bloody diarrhea in developed countries. The aim of this study was to determine whether E. coli O157:H7 is a possible pathogen of bloody diarrhea in southern Iran. Out of 719 children with diarrhea, 243 (34%) patients with positive occult blood took part in our study. The polyclonal antibody test and polymerase chain reaction (PCR) were used to identify E. coli O157:H7. Stool cultures showed enteropathogens in 107 patients (44%). Shigella (34.3%) was followed by E. coli (8.6%), campylobacter (2%) and salmonella (0.4%). None of the E. coli species was of O157:H7 serotype. Antibiotic sensitivity of shigella species was 100% to ceftriaxone, ciprofloxacin and ceftazidime, 94% to nalidixic acid and 13% to co-trimoxazole. The results of the study showed that E. coli O157:H7 is not a cause of bloody diarrhea in our area.
authors.affiliation: Prof Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Abdolvahab
authors.initials: A
authors.lastname: Alborzi
authors.forename: Mohammad Hassan
authors.initials: MH
authors.lastname: Aelami
authors.forename: Behrooz
authors.initials: B
authors.lastname: Astaneh
authors.forename: Bahman
authors.initials: B
authors.lastname: Pourabbas
authors.forename: Shohreh
authors.initials: S
authors.lastname: Farshad
authors.forename: Mehdi
authors.initials: M
authors.lastname: Kalani
authors.forename: Jalil
authors.initials: J
authors.lastname: Nasiri
authors.forename: Mahmood
authors.initials: M
authors.lastname: Rashidi
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002167:Campylobacter / Q000302:isolation & purification / Q000472:pathogenicity*; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000145:classification / Q000382:microbiology* / Q000503:physiopathology; D004927:Escherichia coli Infections / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007492:Iran; D016015:Logistic Models; D008826:Microbial Sensitivity Tests; D009780:Occult Blood; D011446:Prospective Studies; D012703:Serotyping; D012760:Shigella / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents