title: On Spo16 and the coefficient of coincidence.
abstract: spo16 mutants in yeast were reported to have reduced map lengths, a high frequency of nondisjunction in the first meiotic division, and essentially unchanged coefficients of coincidence. Were all crossing over in yeast subject to interference, such data would suggest that the "designation" of recombination events to become crossovers is separable from the "implementation" of that crossing over. In the presence of coexisting interference and noninterference phases of crossing over, however, lack of change in the coefficient of coincidence may show only that spo16 reduces crossing over in the two phases by a similar factor.
authors.affiliation: Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403-1229, USA. fstahl@uoregon.edu
authors.forename: Franklin W
authors.initials: FW
authors.lastname: Stahl
authors.forename: Henriette M
authors.initials: HM
authors.lastname: Foss
mesh_terms: D003434:Crossing Over, Genetic / Q000235:genetics*; D008869:Microtubule-Associated Proteins / Q000235:genetics*; D008957:Models, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*
chemical_list: D008869:Microtubule-Associated Proteins; D029701:Saccharomyces cerevisiae Proteins; C527704:Spo16 protein, S cerevisiae