[Use of psychotropic drugs in children].
The need for specific psychopharmacology trials in the pediatric population has been recognized and promoted by clinicians and regulatory instances. There are indeed specificities in symptom expression and pharmacological characteristics in this population, and recent studies showed that extrapolation from adult data is not always possible. Available results are insufficient to provide effective guidance for prescription and long-term evaluation of risk/benefit ratio in most indications. The aim of this article is to give an overview of efficacy and safety data in pediatric psychopharmacology.
Purper-Ouakil
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Service de psychopathologie de l'enfant et de l'adolescent, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France. diane.purper-ouakil@rdb.aphp.fr
D000293:Adolescent; D000367:Age Factors; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000188:drug therapy; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D002648:Child; D018849:Controlled Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy; D011307:Drug Prescriptions; D004775:Enuresis / Q000188:drug therapy; D005473:Fluoxetine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D015201:Meta-Analysis as Topic; D008774:Methylphenidate / Q000627:therapeutic use; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
D018687:Antidepressive Agents, Second-Generation; D014150:Antipsychotic Agents; D000697:Central Nervous System Stimulants; D005473:Fluoxetine; D008774:Methylphenidate; D011619:Psychotropic Drugs; D017367:Selective Serotonin Reuptake Inhibitors