title: Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici.
abstract: The microbial transformation of coumarin (1) and 6-methyl coumarin (2) using Colletotrichum capsici gave 2-(3'-hydroxypropyl) phenol (3) and 2-(3'-hydroxypropyl)-4-methyl phenol (4). The phytopathogenic fungi effectively reduced the 2H-pyran-2-one moiety of both parent coumarins to respective alcohols.
authors.affiliation: T R Govindachari Centre for Natural Products, SPIC Science Foundation, Chennai, India. gnkgroup@yahoo.co.uk
authors.forename: Gadepalli Narasimha Krishna
authors.initials: GN
authors.lastname: Kumari
authors.forename: Munuswamy Ramanujam
authors.initials: MR
authors.lastname: Ganesh
authors.forename: Rajasekar
authors.initials: R
authors.lastname: Anitha
authors.forename: Aravind
authors.initials: A
authors.lastname: Sivasubramanian
mesh_terms: D020231:Colletotrichum / Q000378:metabolism*; D003374:Coumarins / Q000737:chemistry / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D011714:Pyrans / Q000737:chemistry / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D003374:Coumarins; D011714:Pyrans; C030123:coumarin; C018096:6-methylcoumarin