Epidemiological association between fasting plasma glucose and shortened APTT.
OBJECTIVE
To investigate the relationship between fasting plasma glucose (FPG) and shortened activated partial thromboplastin time (APTT), an independent risk factor for thrombosis.


METHODS
We analyzed outpatients' results of coagulation tests and FPG.


RESULTS
When compared with euglycemic subjects, those with impaired fasting glucose and diabetes displayed significantly shortened APTTs.


CONCLUSIONS
This previously unreported association deserves scrutiny, because APTT is relatively inexpensive and it might identify diabetic patients at major risk of thrombosis.
Lippi
Giuseppe
G
Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37134-Verona, Italy. ulippi@tin.it
Franchini
Massimo
M
Targher
Giovanni
G
Montagnana
Martina
M
Salvagno
Gian Luca
GL
Guidi
Gian Cesare
GC
Favaloro
Emmanuel J
EJ
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D005215:Fasting; D006801:Humans; D008875:Middle Aged; D010314:Partial Thromboplastin Time
D001786:Blood Glucose