[Problem of increasing resistance of pseudomonas aeruginosa in patients at ENT Clinic of Poznan University of Medical Sciences in the years 2005-2007].
INTRODUCTION Species and resistance rate of current pathogens is important for determining the appropriate treatment. P. aeruginosa is an essential issue in the group of patients with ear problems. The number of infections and relapses caused by this pathogen has been increasing with high percentage of antibiotic resistant strains responsible for treatment failure. Aim. The purpose of this work was to present the problem of increasing resistance of Pseudomonas aeruginosa in patients of ENT Department of Poznan University of Medical Sciences between 2005-2007.


METHODS
During that time at our Clinic 644 biological samples were taken to carry out a bacteriological examination. All materials were analyzed to assess the prevalence of Pseudomonas aeruginosa as an etiologic factor of infections. The groups of patients treated operatively and in outpatient clinic were taken into consideration.


RESULTS
Pseudomonas aeruginosa was found in 89 samples; most cases in 2007 (53 strains), which constitutes 18% of all samples analyzed. Predominatingly (in 54 samples) that pathological culture was found in materials coming from ears. There was noticed a 20%--rowth in the number of P. aeruginoso infections in 2007 in relation to 2005. Most of the strains (93%) were susceptible to imipenem, piperacilin and tazobactam, 83% of the strains--to ciprofloxacin, 86%--to ceftazidim.


CONCLUSIONS
Overuse of cotrimoxazol, doxycyclin and cefuroxim in empiric treatment, Pseudomonas aeruginosa strains are naturally resistant to which, is responsible for the . aeruginosa resistance to most commonly used antibiotics.
Tomczak
Hanna
H
Centralne Laboratorium Mikrobiologiczne Szpitala Klinicznego im. H. Swiecickiego w Poznaniu.
Wierzbicka
Małgorzata
M
Okrutnik
Dominika
D
Bartochowska
Anna
A
Łuś
Agnieszka
A
Horla
Anna
A
Szyfter
Witold
W
D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D010031:Otitis / Q000188:drug therapy* / Q000382:microbiology*; D011044:Poland; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D012008:Recurrence; D013045:Species Specificity