title: Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty acids.
abstract: Today, eggs with an increased content of -3 fatty acids are available but there are few publications on the effects of consumption of such eggs on the lipoproteins and acute phase markers in humans. The aim of the present study was to evaluate the effects of consumption of standard eggs and -3 enriched eggs on lipoproteins, glucose and inflammation markers. Nineteen healthy volunteers consumed one extra egg per day of either standard eggs or omega-3 enriched eggs in a double-blind, cross-over study. The duration of each period was 1 month. The effects of the different egg diets on apolipoprotein A1 and B (Apo A1 and B), lipoprotein (a), creatinine, cystatin C, C-reactive protein, serum amyloid protein A, interleukin 6, triglycerides, glucose, total-, high-density lipoprotein and low-density lipo-protein cholesterol concentrations were analyzed. Addition of one regular egg per day to the normal diet had no negative impact on blood lipids or inflammation markers. Consumption of omega-3 enriched eggs resulted in higher levels of ApoA1, lower ApoB/ApoA1 ratio and lower plasma glucose. These effects have been associated in previous studies with a reduced risk for cardiovascular mortality and diabetes.
authors.affiliation: Primary Health Care, Landstinget Västmanland, Section of Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden.
authors.forename: Marie
authors.initials: M
authors.lastname: Ohman
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Akerfeldt
authors.forename: Ingela
authors.initials: I
authors.lastname: Nilsson
authors.forename: Christer
authors.initials: C
authors.lastname: Rosen
authors.forename: Lars-Olof
authors.initials: LO
authors.lastname: Hansson
authors.forename: Martin
authors.initials: M
authors.lastname: Carlsson
authors.forename: Anders
authors.initials: A
authors.lastname: Larsson
mesh_terms: D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D018592:Cross-Over Studies; D004042:Dietary Fats, Unsaturated / Q000378:metabolism*; D004311:Double-Blind Method; D004531:Eggs; D005227:Fatty Acids / Q000097:blood; D015525:Fatty Acids, Omega-3 / Q000378:metabolism*; D005260:Female; D005527:Food, Fortified; D006801:Humans; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D010743:Phospholipids / Q000097:blood
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D001798:Blood Proteins; D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D010743:Phospholipids