title: A simple assay to probe disease-associated enzyme activity using glycosaminoglycan-assisted synthesized gold nanoparticles.
abstract: A simple assay to probe disease-associated enzyme activity using glycosaminoglycan-assisted synthesized gold nanoparticles is reported.
authors.affiliation: Department of Biological Engineering, Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. zban@mail.rochester.edu rams@mit.edu
authors.forename: Zhihui
authors.initials: Z
authors.lastname: Ban
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Bosques
authors.forename: Ram
authors.initials: R
authors.lastname: Sasisekharan
mesh_terms: D015374:Biosensing Techniques; D006025:Glycosaminoglycans / Q000378:metabolism*; D006046:Gold / Q000737:chemistry*; D006497:Heparan Sulfate / Q000378:metabolism; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000201:enzymology*; D011133:Polysaccharide-Lyases / Q000378:metabolism*
chemical_list: D006025:Glycosaminoglycans; D006046:Gold; D006497:Heparan Sulfate; D011133:Polysaccharide-Lyases; C021349:heparitinsulfate lyase