title: "Directed" cardioplegia: a new approach in myocardial protection in left main coronary artery disease.
abstract: "Directed cardioplegia" is a novel approach in myocardial protection in which a certain volume of cardioplegic solution is diverted into a severely diseased coronary artery after surgical occlusion of the other main branches that can be accessed by the surgeon. In this way, the surgeon is able to eliminate the cardioplegic steal from a severely stenosed vessel through other less severely diseased and/or patent arteries during the nonselective antegrade administration of cardioplegia and to protect myocardial regions, which are poorly perfused. We performed this new technique in 2 patients with severe left main coronary artery disease with excellent results.
authors.affiliation: Department of Cardiac Surgery, Aghia Sophia Hospital, Athens, Greece.
authors.forename: Ilias A
authors.initials: IA
authors.lastname: Kouerinis
authors.forename: Marina M
authors.initials: MM
authors.lastname: Palaiologou
authors.forename: Michalis
authors.initials: M
authors.lastname: Argiriou
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Dedeilias
authors.forename: Efstratios
authors.initials: E
authors.lastname: Apostolakis
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Giannakopoulou
authors.forename: George
authors.initials: G
authors.lastname: Papadopoulos
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Tsilimingas
mesh_terms: D000368:Aged; D002314:Cardioplegic Solutions / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002315:Cardiopulmonary Bypass / Q000379:methods; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006324:Heart Arrest, Induced / Q000379:methods*; D006334:Heart Function Tests; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D002314:Cardioplegic Solutions