title: Nickel-catalyzed alkenylation and alkylation of fluoroarenes via activation of C-H bond over C-F bond.
abstract: Nickel/P(c-C(5)H(9))(3) (PCyp(3)) catalyst effects the addition reactions of fluoroarenes across alkynes, 1,3-dienes, and vinylarenes via the activation of C-H bonds over C-F bonds. The acidic C-H bonds located ortho to fluorine are exclusively activated to afford a range of alkenylated and alkylated fluoroarenes.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. yoshiakinakao@npc05.mbox.media.kyoto-u.ac.jp
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao
authors.forename: Natsuko
authors.initials: N
authors.lastname: Kashihara
authors.forename: Kyalo Stephen
authors.initials: KS
authors.lastname: Kanyiva
authors.forename: Tamejiro
authors.initials: T
authors.lastname: Hiyama
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000478:Alkylation; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*
chemical_list: D000475:Alkenes; D005461:Fluorine; D002244:Carbon; D009532:Nickel; D006859:Hydrogen