title: Malignant glomus tumor of the hand.
abstract: Malignant glomus tumors, or glomangiosarcomas, are rare soft tissue tumors and usually represent a locally infiltrative malignancy. They have been reported in many different anatomic locations with the lower extremity and abdominal viscera being the most common. Their location in the hand is extremely rare. Glomangiosarcomas tend to pursue a benign course with local aggressiveness. However, metastasis can occur and is associated with a poor prognosis. Different classification systems have been proposed based on histologic criteria. We present an unusually large, aggressive glomangiosarcoma at the tip of the long finger in a 33-year-old pregnant woman.
authors.affiliation: Department of Pathology, Los Angeles County Medical Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA. stepheno@usc.edu
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Oh
authors.forename: Daniel
authors.initials: D
authors.lastname: Stephenson
authors.forename: Stephen
authors.initials: S
authors.lastname: Schnall
authors.forename: Isabella
authors.initials: I
authors.lastname: Fassola
authors.forename: Paul
authors.initials: P
authors.lastname: Dinh
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D005260:Female; D005385:Fingers / Q000473:pathology* / Q000601:surgery; D005918:Glomus Tumor / Q000473:pathology* / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D012509:Sarcoma / Q000473:pathology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D000199:Actins; D019253:Proto-Oncogene Proteins c-bcl-2