title: Fatal relapse of disseminated strongyloidiasis in an HIV-positive patient, despite ivermectin treatment.
abstract: There are no established guidelines for the treatment of disseminated strongyloidiasis in immunosuppressed patients, and many different treatment regimens have been used. Here, the case of a 48-year-old, HIV-positive, Congolese man, who was hospitalized for disseminated tuberculosis but developed life-threatening disseminated strongyloidiasis, is described. This patient died, with relapsing disseminated strongyloidiasis, 3 months after being treated with ivermectin. The reasons for this poor outcome and the various treatment options for strongyloidiasis in HIV-infected patients are discussed.
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Service de Maladies Infectieuses et Tropicales, 47-83 Boulevard de l'Hôpital, F-75013 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Mattioni
authors.forename: N
authors.initials: N
authors.lastname: Valin
authors.forename: C
authors.initials: C
authors.lastname: Cracco
authors.forename: M
authors.initials: M
authors.lastname: Thellier
authors.forename: M
authors.initials: M
authors.lastname: Danis
authors.forename: E
authors.initials: E
authors.lastname: Caumes
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D017809:Fatal Outcome; D006679:HIV Seropositivity; D006801:Humans; D016867:Immunocompromised Host; D007559:Ivermectin / Q000627:therapeutic use*; D008174:Lung Diseases, Parasitic / Q000188:drug therapy* / Q000821:virology; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D017171:Strongyloides stercoralis; D013322:Strongyloidiasis / Q000188:drug therapy* / Q000821:virology; D014376:Tuberculosis / Q000469:parasitology / Q000821:virology
chemical_list: D000969:Antinematodal Agents; D007559:Ivermectin