title: Improvement in renal dysfunction and symptoms after laparoscopic adrenalectomy in a patient with pheochromocytoma complicated by renal dysfunction.
abstract: A 70-year-old patient who was undergoing treatment for diabetes mellitus and chronic hepatitis was admitted to our hospital for evaluation of a tumor in the left adrenal gland (50 x 45 mm) and renal failure. On the basis of the patient's increased serum concentrations of catecholamines and other metabolites and the results of positron emission tomography (PET), the patient was diagnosed with a pheochromocytoma; iodinated metaiodobenzylguanidine ([(131)I]MIBG) scintigraphy was insufficient to establish this diagnosis. Subsequently, he underwent surgery for tumor resection. Histological examination suggested the tumor to be a malignant pheochromocytoma. After left adrenalectomy was performed, the elevated catecholamine and metabolite concentrations and the blood pressure were restored to normal, and the patient's symptoms of severe headaches and vertigo reduced. Furthermore, his renal function improved (Cr 2.0-1.2 mg/dl). Our patient exhibited a rare condition of pheochromocytoma complicated by renal failure, which was successfully treated with laparoscopic surgery.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, 761-0793, Japan.
authors.forename: Mako
authors.initials: M
authors.lastname: Fujiwara
authors.forename: Hitomi
authors.initials: H
authors.lastname: Imachi
authors.forename: Koji
authors.initials: K
authors.lastname: Murao
authors.forename: Tomie
authors.initials: T
authors.lastname: Muraoka
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Ohyama
authors.forename: Yumi
authors.initials: Y
authors.lastname: Miyai
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kushida
authors.forename: Reiji
authors.initials: R
authors.lastname: Haba
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kakehi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Ishida
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D000368:Aged; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D010535:Laparoscopy / Q000379:methods; D008297:Male; D010673:Pheochromocytoma / Q000150:complications / Q000601:surgery*; D020127:Recovery of Function; D051437:Renal Insufficiency / Q000150:complications / Q000503:physiopathology / Q000601:surgery*