HLA-A*3318, a novel allele, identified by sequence-based typing in a Chinese individual.
We report a novel human leucocyte antigen (HLA)-A allele, officially named as A*3318, which was found during high-resolution sequence-based typing in a Chinese potential hematopoietic stem cell transplantation donor. Compared with the HLA-A*330301 sequence, the A*3318 has one nucleotide substitution in exon 3: at nt 413 where A-->G resulting in an amino acid substitution from Q (CAG) to R (CGG) at codon 114.
Li
Z
Z
Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong Province, China. shallylizhen@yahoo.com.cn
Zhang
L-H
LH
Zou
H-Y
HY
Cheng
L-H
LH
Jin
S-Z
SZ
Wang
D-M
DM
Cheng
X
X
D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution / Q000235:genetics*; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D002681:China; D005091:Exons / Q000235:genetics; D015234:HLA-A Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D015234:HLA-A Antigens