title: Psychological profile of adolescents with a kidney transplant.
abstract: To describe the psychological profile of renal transplant adolescents compared to healthy peers and to adolescents with CKD, three groups of adolescents aged 12-18 yr were selected: TX, CX, and adolescents with CKD. Psychiatric symptoms and disorders were evaluated through direct interviews (K-SADS-PL) and self-report questionnaires (YSR and CBCL). Forty TX (14 LRD and 26 DD transplant recipients), 40 CX and 20 CKD were included. Twelve of 40 (30%) TX, three of 20 (15%) CKD, and three of 40 (7.5%) CX had a history of learning difficulties (p = 0.03). Compared to CX, TX had lower total YSR competencies score (p = 0.028) and lower total CBCL competencies score (p = 0.003). Twenty-six of 40 (65%) TX, 12 of 20 (60%) CKD and 15 of 40 (37.5%) CX (p = 0.038) met DSM-IV diagnostic criteria for lifetime psychiatric disorder, with rates of depressive disorder of 35% among TX and CKD compared to 15.2% among CX (p = 0.043). Eight of 40 (20%) TX had a history of simple phobia. Nine of 40 (22.5%) TX met diagnostic criteria for ADHD as compared to one of 20 (5%) CKD and three of 40 (7.5%) CX. In the TX group, we found no significant differences in educational and psychiatric variables between LRD and DD. In conclusion, we found a high prevalence of psychiatric morbidity (depression, phobia, ADHD), educational impairment and social competence problems in the TX group. CKD scored in between TX and CX on most measures.
authors.affiliation: Department of Psychiatry, Lausanne University Hospital, Switzerland.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Berney-Martinet
authors.forename: Fiona
authors.initials: F
authors.lastname: Key
authors.forename: Lorraine
authors.initials: L
authors.lastname: Bell
authors.forename: Suzanne
authors.initials: S
authors.lastname: Lépine
authors.forename: Marie-José
authors.initials: MJ
authors.lastname: Clermont
authors.forename: Eric
authors.initials: E
authors.lastname: Fombonne
mesh_terms: D000293:Adolescent; D002648:Child; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology* / Q000628:therapy*; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D001523:Mental Disorders / Q000150:complications; D015995:Prevalence; D012923:Social Class; D011795:Surveys and Questionnaires; D016896:Treatment Outcome