title: Long-standing spiny papules on the lower extremities. Flegel disease, or hyperkeratosis lenticularis perstans (HLP).
authors.affiliation: University of British Columbia and St Paul's Hospital, Vancouver, British Columbia, Canada.
authors.forename: Shannon
authors.initials: S
authors.lastname: Humphrey
authors.forename: Richard I
authors.initials: RI
authors.lastname: Crawford
authors.forename: Sheila
authors.initials: S
authors.lastname: Au
mesh_terms: D000287:Administration, Topical; D001707:Biopsy, Needle; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007642:Keratosis / Q000188:drug therapy / Q000473:pathology*; D007868:Leg Dermatoses / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D009824:Ointments; D011379:Prognosis; D017444:Skin Diseases, Papulosquamous / Q000188:drug therapy / Q000473:pathology*; D014508:Urea / Q000627:therapeutic use
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; D014508:Urea