title: Update on the epidemiology and diagnosis of invasive fungal infection.
abstract: In recent years, the most important advances in the treatment of transplant recipients, patients with haematological neoplasm and critically ill patients have been accompanied by an increase in the incidence of common fungal diseases and the emergence of some less common ones. Although new techniques (e.g. galactomannan detection) and new antifungals have appeared, these opportunistic infections remain difficult to diagnose and have a high mortality. New diagnostic techniques could improve this outlook, although they are far from becoming available in daily practice.
authors.affiliation: Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. mcuenca-estrella@iscii.es
authors.forename: Manuel
authors.initials: M
authors.lastname: Cuenca-Estrella
authors.forename: Leticia
authors.initials: L
authors.lastname: Bernal-Martinez
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Buitrago
authors.forename: Maria Victoria
authors.initials: MV
authors.lastname: Castelli
authors.forename: Alicia
authors.initials: A
authors.lastname: Gomez-Lopez
authors.forename: Oscar
authors.initials: O
authors.lastname: Zaragoza
authors.forename: Juan Luis
authors.initials: JL
authors.lastname: Rodriguez-Tudela
mesh_terms: D016638:Critical Illness; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D009181:Mycoses / Q000175:diagnosis* / Q000453:epidemiology* / Q000401:mortality