title: Antioxidant capacity and antimutagenic activity of natural oleoresin from greenhouse grown tomatoes (Lycopersicon esculentum).
abstract: Natural oleoresins rich in lycopene were obtained from two varieties of tomato (Zedona and Gironda) and their nutraceutical potential (antioxidant and antimutagenic capacity) was evaluated. Both oleoresins had a high content of lycopene, 58.33+/-1.67 mg/g (Zedona) and 63.97+/-0.80 mg/g (Gironda). The antioxidant activity (AA) of the oleoresins by beta-carotene method were 56.4-74.5% (Zedona) and 51-72.8% (Gironda), while when using the free radical stable 2,2-diphenyl-picryl-hydrazyl (DPPH) method, the antiradical activity (ARA) was determined to be 18.2-32.7% (Zedona) and 16.6-26.7% (Gironda) for the concentrations tested that of 200-400 microM equivalents of lycopene. The antimutagenic activity of the oleoresins was tested against aflatoxin B1 (AFB1) using the microsuspension assay, both varieties had a very high antimutagenic potential against AFB1 (60-66%).These results suggest the NCRT can be taken advantage to obtaining rich oleoresin in lycopene with a nutraceutical value.
authors.affiliation: Centro de Estudios Académicos sobre Contaminación Ambiental, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Qro, 76010, Mexico.
authors.forename: Eustolia
authors.initials: E
authors.lastname: Rodríguez-Muñoz
authors.forename: Gilberto
authors.initials: G
authors.lastname: Herrera-Ruiz
authors.forename: Gustavo
authors.initials: G
authors.lastname: Pedraza-Aboytes
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Loarca-Piña
mesh_terms: D016604:Aflatoxin B1 / Q000633:toxicity; D016587:Antimutagenic Agents / Q000032:analysis / Q000378:metabolism*; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism*; D002338:Carotenoids / Q000032:analysis / Q000378:metabolism*; D016166:Free Radical Scavengers; D006801:Humans; D000077276:Lycopene; D018551:Solanum lycopersicum / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis / Q000378:metabolism*
chemical_list: D016587:Antimutagenic Agents; D000975:Antioxidants; D016166:Free Radical Scavengers; D010936:Plant Extracts; C018620:oleoresins; D002338:Carotenoids; D016604:Aflatoxin B1; D000077276:Lycopene