Evaluation of the rapid BioStar optical immunoassay for detection of Chlamydia trachomatis in adolescent women.
We evaluated the performance of the BioStar Chlamydia OIA (optical immunoassay) in adolescent females (n = 261) from an inner city population. With a reference standard of two different nucleic acid amplification tests, the sensitivity and specificity of the BioStar Chlamydia OIA were 59.4 and 98.4%, respectively. Due to its relatively low sensitivity, the BioStar Chlamydia OIA should only be used in conjunction with more sensitive laboratory tests unless laboratory tests are unavailable or timely return for treatment is unlikely.
Bandea
Claudiu I
CI
National Center for Infectious Diseases, Centers for Disease Control and Prevention, MS C-17, 1600 Clifton Rd., Atlanta, GA 30333, USA.
Koumans
Emilia H
EH
Sawyer
Mary K
MK
Dover
Jason
J
O'Connor
Angelica
A
Papp
John R
JR
Unger
Elizabeth R
ER
Braxton
Jim
J
Black
Carolyn M
CM
D000293:Adolescent; D001431:Bacteriological Techniques / Q000379:methods*; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007118:Immunoassay; D012680:Sensitivity and Specificity; D014505:Urban Population; D055815:Young Adult