title: Leukemia cutis in a patient with acute monocytic leukemia presenting as unique facial erythema.
abstract: A 67-year-old woman was referred to our department with a 1-month history of facial exanthemas. She had been diagnosed as having acute monocytic leukemia (French-American-British classification, M5b) based on the histological findings of bone marrow. Physical examination revealed diffuse edematous erythema on her cheeks, eyelids and glabella with scattered reddish papules. Histological examination demonstrated dense infiltration of atypical mononuclear cells in the dermis. Specific cutaneous lesions could occur in acute monocytic leukemia more frequently than in other types of leukemia, but rarely show symmetrical edematous erythema limited to the face.
authors.affiliation: Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan. tohatt@showa.gunma-u.ac.jp
authors.forename: Tomoyasu
authors.initials: T
authors.lastname: Hattori
authors.forename: Hiroo
authors.initials: H
authors.lastname: Amano
authors.forename: Yayoi
authors.initials: Y
authors.lastname: Nagai
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishikawa
mesh_terms: D000368:Aged; D004890:Erythema / Q000175:diagnosis* / Q000209:etiology; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000175:diagnosis / Q000473:pathology*; D017254:Leukemic Infiltration / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology*