Congenital fibrosarcoma as cause for fetal anemia: prenatal diagnosis and in utero treatment.
OBJECTIVE
To discuss diagnosis and management of a case of a rare fetal tumor complicated by fetal anemia due to intratumoral hemorrhage.


METHODS
We report on a 29-week-old fetus with a tumor in the posterior left shoulder region. The morphologic aspect of the tumor, lack of fetal movements and an increased middle cerebral artery (MCA) peak systolic velocity (PSV) were indicative of fetal anemia caused by intratumoral bleeding. Following intravascular blood transfusion the pregnancy was safely prolonged for 15 days, during which lung maturity was induced. After delivery the neonate underwent surgical excision. Histological examination revealed an infantile congenital fibrosarcoma.


CONCLUSIONS
Anemia must be ruled out in cases with fetal tumors. MCA PSV is useful in diagnosis and surveillance in these fetuses.
Scheier
Matthias
M
Department of Obstetrics and Gynecology, Innsbruck Medical University, Innsbruck, Austria. matthias.scheier@uki.at
Ramoni
Angela
A
Alge
Alexander
A
Brezinka
Christoph
C
Reiter
Gernot
G
Sergi
Consolato
C
Hager
Josef
J
Marth
Christian
C
D000328:Adult; D000740:Anemia / Q000151:congenital / Q000209:etiology* / Q000628:therapy*; D001783:Blood Flow Velocity; D001805:Blood Transfusion, Intrauterine; D005260:Female; D005354:Fibrosarcoma / Q000150:complications* / Q000151:congenital / Q000000981:diagnostic imaging*; D006470:Hemorrhage / Q000151:congenital / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D020768:Middle Cerebral Artery / Q000502:physiology; D011247:Pregnancy; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000151:congenital / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal