Paecilomyces lilacinus peritonitis complicating peritoneal dialysis cured by oral voriconazole and terbinafine combination therapy.
Fungal peritonitis (FP) is a serious complication in patients on continuous ambulatory peritoneal dialysis (CAPD). We report a case of CAPD-related FP caused by Paecilomyces lilacinus in a 15-year-old uraemic boy. The infection was successfully treated by combination therapy consisting of oral voriconazole and terbinafine, which has not been previously reported in the treatment of FP.
Chang
Brian Pin-Hsuan
BP
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Sun
Pei-Lun
PL
Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
Huang
Fu-Yuan
FY
Department of Pediatrics, Taipei Medical University, Taipei, Taiwan.|Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Tsai
Tsuen-Chiuan
TC
Department of Pediatrics, Taipei Medical University Wan-Fang Hospital, Taipei, Taiwan.
Lin
Chun-Chen
CC
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Lee
Ming-Dar
MD
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Chen
Yee-Chun
YC
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Sheu
Jin-Cherng
JC
Department of Pediatric Surgery, Mackay Memorial Hospital, Taipei, Taiwan.
Tsai
Jeng-Daw
JD
Department of Pediatrics, Taipei Medical University, Taipei, Taiwan.|Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
D000284:Administration, Oral; D000293:Adolescent; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use; D010143:Paecilomyces / Q000187:drug effects / Q000302:isolation & purification*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use; D000077291:Terbinafine; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D009281:Naphthalenes; D011743:Pyrimidines; D014230:Triazoles; D000077291:Terbinafine; D065819:Voriconazole