Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici.
The microbial transformation of coumarin (1) and 6-methyl coumarin (2) using Colletotrichum capsici gave 2-(3'-hydroxypropyl) phenol (3) and 2-(3'-hydroxypropyl)-4-methyl phenol (4). The phytopathogenic fungi effectively reduced the 2H-pyran-2-one moiety of both parent coumarins to respective alcohols.
Kumari
Gadepalli Narasimha Krishna
GN
T R Govindachari Centre for Natural Products, SPIC Science Foundation, Chennai, India. gnkgroup@yahoo.co.uk
Ganesh
Munuswamy Ramanujam
MR
Anitha
Rajasekar
R
Sivasubramanian
Aravind
A
D020231:Colletotrichum / Q000378:metabolism*; D003374:Coumarins / Q000737:chemistry / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D011714:Pyrans / Q000737:chemistry / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared
D003374:Coumarins; D011714:Pyrans; C030123:coumarin; C018096:6-methylcoumarin