Possible role for dietary lutein and zeaxanthin in visual development.
The possibility that the macular carotenoids, lutein (L), and zeaxanthin (Z), could retard age-related changes in the eye and prevent the eye diseases that result from such changes (namely, cataract and macular degeneration) has been carefully studied. A role for the carotenoids very early in life, however, has received far less attention. Nevertheless, an influence on visual development is likely. Retinal L and Z, for instance, would influence the development of the visual system if they 1) altered input during a critical/sensitive period of visual development and/or 2) influenced maturation and/or 3) protected the retina during a period when it was particularly vulnerable. The available evidence indicates that the pigments may play a role in all three of these areas.
Hammond
Billy R
BR
Vision Sciences Laboratory, University of Georgia, Athens, Georgia 30602, USA.
D002386:Cataract / Q000378:metabolism / Q000517:prevention & control*; D006801:Humans; D014975:Lutein / Q000008:administration & dosage* / Q000378:metabolism; D008268:Macular Degeneration / Q000378:metabolism / Q000517:prevention & control*; D014785:Vision, Ocular / Q000187:drug effects / Q000502:physiology; D024341:Xanthophylls / Q000008:administration & dosage* / Q000378:metabolism; D065146:Zeaxanthins
D024341:Xanthophylls; D065146:Zeaxanthins; D014975:Lutein