title: Two novel thiophenes from Echinops grijissi Hance.
abstract: Two novel thiophenes, grijisyne A (1), and grijisone A (2), were isolated from the crude ethanolic extract of the roots of Echinops grijissi Hance. Their structures were determined by spectral methods, especially 2D NMR spectra. All the isolated compounds were tested for their anti-tumor activities against three human tumor cell lines, HL-60, K562, and MCF-7.
authors.affiliation: College of Pharmaceutical Sciences, Zhejiang University, Institute of Pharmaceutical Informatics, Hangzhou, Zhejiang, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Wen-Rong
authors.initials: WR
authors.lastname: Jin
authors.forename: Qiang
authors.initials: Q
authors.lastname: Shi
authors.forename: Hua
authors.initials: H
authors.lastname: He
authors.forename: Zhong-Jun
authors.initials: ZJ
authors.lastname: Ma
authors.forename: Hai-Bin
authors.initials: HB
authors.lastname: Qu
mesh_terms: D031182:Echinops Plant / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D013876:Thiophenes; C539150:grijisone A; C539151:grijisyne A