title: The TachoSil-Pledget stitch: towards eradication of suture hole bleeding.
abstract: We describe a novel suture consisting of a small piece of TachoSil (Nycomed, Copenhagen, Denmark) and a felt pledget-the TachoSil-pledget stitch-which was used to facilitate mechanical and biologic hemostasis in 5 patients undergoing aortic arch aneurysm repair. The TachoSil-pledget stitch achieved good or very good hemostasis at all 56 bleeding points to which it was applied, while 5 of 12 points to which a conventional felt-pledget stitch was applied required additional stitching or an additional hemostatic method.
authors.affiliation: Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimamoto
authors.forename: Akira
authors.initials: A
authors.lastname: Marui
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nishina
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Saji
authors.forename: Masashi
authors.initials: M
authors.lastname: Komeda
mesh_terms: D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D016063:Blood Loss, Surgical / Q000517:prevention & control; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D015331:Cohort Studies; D004338:Drug Combinations; D005260:Female; D005340:Fibrinogen / Q000494:pharmacology*; D006488:Hemostasis, Surgical / Q000295:instrumentation*; D006801:Humans; D008297:Male; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013536:Suture Techniques / Q000295:instrumentation*; D013537:Sutures; D013718:Tensile Strength; D013917:Thrombin / Q000494:pharmacology*; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; C518955:TachoSil; D005340:Fibrinogen; D013917:Thrombin