The antecedents of biliary cancer: a primary care case-control study in the United Kingdom.
In a case-control study using a large UK primary care database, we found that non-steroidal anti-inflammatory drugs had no protective effect against biliary carcinomas (cholangiocarcinoma and gall bladder cancer). Increased risks were observed for cigarette smoking, diabetes, gallstone disease and obesity.
Grainge
M J
MJ
Division of Epidemiology and Public Health, School of Community Health Sciences, University of Nottingham, Nottingham NG7 2UH, UK.
West
J
J
Solaymani-Dodaran
M
M
Aithal
G P
GP
Card
T R
TR
D000368:Aged; D000428:Alcohol Drinking; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001650:Bile Duct Neoplasms / Q000209:etiology*; D001653:Bile Ducts, Intrahepatic; D015992:Body Mass Index; D016022:Case-Control Studies; D018281:Cholangiocarcinoma / Q000209:etiology*; D005260:Female; D005706:Gallbladder Neoplasms / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D006113:United Kingdom
D000894:Anti-Inflammatory Agents, Non-Steroidal