Imaging pulsatile retinal blood flow in human eye.
A functional Fourier domain optical coherence tomography instrument offering spectral Doppler imaging of in vivo pulsatile human retinal blood flow was constructed. An improved phase-resolved algorithm was developed to correct bulk motion artifacts. Spectral Doppler imaging provides complementary temporal flow information to the spatially distributed flow information of the color Doppler image by providing direct visualization of the Doppler spectrum of the flow whose pattern can be further quantified with various velocity envelope curves and their corresponding flow indices. The coefficient of repeatability on resistance index measurement was assessed by analyzing 14 measurements on two vessels within two normal subjects.
Rao
Bin
B
Yu
Lingfeng
L
Chiang
Huihua Kenny
HK
Zacharias
Leandro C
LC
Kurtz
Ronald M
RM
Kuppermann
Baruch D
BD
Chen
Zhongping
Z
D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D011673:Pulsatile Flow / Q000502:physiology*; D012171:Retinal Vessels / Q000166:cytology* / Q000502:physiology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014655:Vascular Resistance / Q000502:physiology