title: Isolation and structure determination of the biologically active sphingolipids from marine sponge Haliclona species.
abstract: In a continuation to our study on the marine sponge Haliclona species we have isolated three new cytotoxic components of sphingolipids (1-3). Methanolysis of the sphingolipid 1a-d in methanol produces fatty acid methyl ester. GC/MS was used to determine the length. The structure of each isolated compound has been determined on the basis of spectroscopic data and chemical evidence.
authors.affiliation: Faculty of Science, Department of Chemistry, King Abdulaziz University, Jeddah, Saudi Arabia. snayyad2@yahoo.com
authors.forename: Seif-Eldin N
authors.initials: SE
authors.lastname: Ayyad
authors.forename: Saleh Omar S
authors.initials: SO
authors.lastname: Bahaffi
authors.forename: Nadia E
authors.initials: NE
authors.lastname: Hashish
mesh_terms: D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry; D047129:Haliclona / Q000737:chemistry*; D008386:Marine Biology; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009792:Oceans and Seas; D013107:Sphingolipids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D013107:Sphingolipids