title: A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents.
abstract: A robust method for synthesizing structurally diverse metallopeptide libraries using a Re(i) complex of a non-natural amino acid was developed as a way to accelerate the discovery of novel molecular imaging probes.
authors.affiliation: Department of Chemistry, McMaster University, Hamilton, ON, Canada.
authors.forename: Andrea F
authors.initials: AF
authors.lastname: Armstrong
authors.forename: Nick
authors.initials: N
authors.lastname: Oakley
authors.forename: Shannon
authors.initials: S
authors.lastname: Parker
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Causey
authors.forename: Jennifer
authors.initials: J
authors.lastname: Lemon
authors.forename: Alfredo
authors.initials: A
authors.lastname: Capretta
authors.forename: Craig
authors.initials: C
authors.lastname: Zimmerman
authors.forename: John
authors.initials: J
authors.lastname: Joyal
authors.forename: Francis
authors.initials: F
authors.lastname: Appoh
authors.forename: Jon
authors.initials: J
authors.lastname: Zubieta
authors.forename: John W
authors.initials: JW
authors.lastname: Babich
authors.forename: Gurmit
authors.initials: G
authors.lastname: Singh
authors.forename: John F
authors.initials: JF
authors.lastname: Valliant
mesh_terms: D003952:Diagnostic Imaging / Q000639:trends; D008024:Ligands; D008667:Metalloproteins / Q000138:chemical synthesis* / Q000737:chemistry; D015336:Molecular Probe Techniques / Q000639:trends; D015335:Molecular Probes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D019151:Peptide Library; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D012211:Rhenium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D008024:Ligands; D008667:Metalloproteins; D015335:Molecular Probes; D019151:Peptide Library; D010455:Peptides; D012211:Rhenium