title: Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones.
abstract: A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial and antifungal activities were evaluated against S. aureus, S. epidermidis, C. albicans and C. glabrata.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey. sozkir@istanbul.edu.tr
authors.forename: Sumru
authors.initials: S
authors.lastname: Ozkirimli
authors.forename: Fusun
authors.initials: F
authors.lastname: Kazan
authors.forename: Yağmur
authors.initials: Y
authors.lastname: Tunali
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D012545:Schiff Bases / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D013864:Thioglycolates / Q000737:chemistry; D014230:Triazoles / Q000138:chemical synthesis*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D012545:Schiff Bases; D013438:Sulfhydryl Compounds; D013844:Thiazoles; D013864:Thioglycolates; D014230:Triazoles; C017487:2-mercaptoacetate; C023884:thiolactic acid