title: Clinicopathologic features and predictors for survival of mucinous and non-mucinous appendiceal adenocarcinoma.
abstract: OBJECTIVE
  We report a study in patients with mucinous and non-mucinous appendiceal adenocarcinoma treated surgically whose records were examined to elucidate their clinicopathologic features and prognostic factors for survival.
  
  
  METHODS
  The medical records of 34 patients with mucinous and non-mucinous appendiceal adenocarcinoma (1991-2005) were retrospectively reviewed.
  
  
  RESULTS
  There was no significant difference between mucinous and non-mucinous tumors in patient demographics, clinicopathologic features, type of operation and outcome. Non-mucinous tumors had a higher incidence of leukocytosis than mucinous ones. The overall 5-year survival rate for 34 patients with appendiceal adenocarcinoma was 35.8%. In the univariate analysis, predictors of survival were the type of operation, resectability, carcinomatosis and tumor stage. Tumor stage significantly influenced patient survival in the multivariate analysis.
  
  
  CONCLUSIONS
  Mucinous appendiceal adenocarcinoma had clinicopathologic characteristics and a prognosis similar to non-mucinous, except that there was more leukocytosis in non-mucinous tumors. Tumor stage is an independent predictor for survival among patients with appendiceal adenocarcinoma.
authors.affiliation: Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan, ROC.
authors.forename: Jun-Te
authors.initials: JT
authors.lastname: Hsu
authors.forename: Han-Ming
authors.initials: HM
authors.lastname: Chen
authors.forename: Chien-Hung
authors.initials: CH
authors.lastname: Liao
authors.forename: Chun-Nan
authors.initials: CN
authors.lastname: Yeh
authors.forename: Ta-Sen
authors.initials: TS
authors.lastname: Yeh
authors.forename: Tsann-Long
authors.initials: TL
authors.lastname: Hwang
authors.forename: Yi-Yin
authors.initials: YY
authors.lastname: Jan
authors.forename: Miin-Fu
authors.initials: MF
authors.lastname: Chen
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001062:Appendectomy / Q000379:methods; D001063:Appendiceal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011182:Postoperative Care; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis