Inconspicamide, new N-acylated serinol from the marine sponge Stelletta inconspicua.
A new N-acylated serinol, inconspicamide (1), was isolated from the marine sponge, Stelletta inconspicua, together with a glyceryl ether (2). Their structures were determined on the basis of spectroscopic data and the modified Mosher analysis. They exhibited moderate cytotoxic activity against HeLa human cervical cancer cells.
Ueoka
Reiko
R
Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
Fujita
Tsuyoshi
T
Iwashita
Takashi
T
van Soest
Rob W M
RW
Matsunaga
Shigeki
S
D000215:Acylation; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D055808:Drug Discovery; D006367:HeLa Cells; D006801:Humans; D011161:Porifera / Q000737:chemistry*; D011412:Propanolamines; D011409:Propylene Glycols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013229:Stearic Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000970:Antineoplastic Agents; D011412:Propanolamines; D011409:Propylene Glycols; D013229:Stearic Acids; C534727:inconspicamide; C072422:serinol