Clinical trials subject registration and randomization system (SRAR).
In cancer research it is often necessary for subjects registered on clinical trials to be randomly assigned a treatment. There is often a number of stratified randomization lists in a protocol defined by clinical, demographic, or environmental factors of the subject. Upon registration, questions are asked of the subject to aid in determining the subject's stratum. Unique to this application is the ability to programmatically determine eligibility and identify what stratum an individual should be randomized to. The application allows for multi-institutional accruing of subjects over the web. Collaborating institutions securely access the program and register/randomize subjects on the clinical trial. Treatment results are distributed via email, with "blinded" recipients not being notified of the subject's treatment selection. The application was developed using Open-Source technologies.
Grose
Tim E
TE
Moffitt Cancer Center, Tampa, FL, USA.
Birnbaum
Jack
J
D000465:Algorithms; D003627:Data Interpretation, Statistical; D006801:Humans; D018579:Patient Selection; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D014481:United States