title: A case of Moyamoya syndrome and hemoglobin E/beta-thalassemia.
abstract: Moyamoya syndrome is a rare diagnosis that has been linked to a small number of hemoglobinopathies. Children with Moyamoya syndrome tend to present with transient ischemic attacks, mental deficiency, and/or neurological deficits. We describe a case of a 15-year-old Cambodian male with HbE/beta-thalassemia who was found to have left Moyamoya syndrome as part of an evaluation for growth hormone deficiency. The link between Moyamoya syndrome and HbE/beta-thalassemia may be multifactorial, but Moyamoya syndrome is an important consequence to consider in children with HbE/beta-thalassemia.
authors.affiliation: Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: Torrey M
authors.initials: TM
authors.lastname: Parker
authors.forename: Leanne M
authors.initials: LM
authors.lastname: Ward
authors.forename: Donna L
authors.initials: DL
authors.lastname: Johnston
authors.forename: Enrique
authors.initials: E
authors.lastname: Ventureya
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Klaassen
mesh_terms: D006446:Hemoglobin E / Q000378:metabolism*; D006801:Humans; D007223:Infant; D018810:Magnetic Resonance Angiography; D008297:Male; D009072:Moyamoya Disease / Q000097:blood* / Q000150:complications* / Q000473:pathology; D017086:beta-Thalassemia / Q000097:blood* / Q000150:complications* / Q000473:pathology
chemical_list: D006446:Hemoglobin E