title: The confused cancer patient: a case of 5-fluorouracil-induced encephalopathy.
abstract: The fluorinated pyrimidine 5-fluorouracil (5-FU) is an anticancer agent used in most adjuvant and palliative treatment regimens for colorectal cancer. Neurotoxicities are considered extremely rare side effects of 5-FU. Here, we report a case of 5-FU-induced encephalopathy, manifesting as seizures and delirium, in an era of oxaliplatin-containing chemotherapy. If ammonia levels are elevated, lactulose may be considered in the initial management of neuropsychiatric complications from 5-FU.
authors.affiliation: Department of Medical Oncology and Hematology, University of Toronto, Toronto, ON.
authors.forename: W Y
authors.initials: WY
authors.lastname: Cheung
authors.forename: R A
authors.initials: RA
authors.lastname: Fralick
authors.forename: S
authors.initials: S
authors.lastname: Cheng