[Application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors: report of 4 cases].
OBJECTIVE
To evaluate the application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors.


METHODS
Four cases with cranio-maxillofacial bone tumors, including one in the frontal bone and three in the mandible, underwent osteoectomy, autologous diseased bone fresh-frozen by nitrogen, re-implantation of the bone and internal fixation by titanium plate to treat the bone tumor and reconstruct the bone defect.


RESULTS
All four cases had one-stage healing 10-14 days after operation. One patient had pathological bone fracture 2 months postoperatively, the other three patients were well-cured without tumor recurrence and gained satisfied cosmetic appearance during 6 months to 3 years of follow-up. The X-ray films showed that the frozen bone was substituted by new bone formation.


CONCLUSIONS
Autologous bone fresh-frozen and re-implantation is a feasible method in cranio-maxillofacial bone tumor treatment, especially for young patients. It make possible to do radical surgery and reconstruct the bone defect simultaneously, and is thus worthy of clinical application.
Chen
Shun-Yue
SY
Department of Stomatology, Taizhou Shili Hospital, Taizhou 318000, Zhejiang Province, China.
Liu
Zhi-Hui
ZH
Lu
Yu
Y
Hu
Yong-Jie
YJ
D001860:Bone Plates; D016025:Bone Transplantation; D015925:Cryopreservation; D005153:Facial Neoplasms / Q000601:surgery*; D006801:Humans; D008334:Mandible; D008339:Mandibular Neoplasms / Q000601:surgery*; D019651:Plastic Surgery Procedures