[Randomised controlled trials (RCTs)].
Randomisation is regarded as an essential principle ensuring the internal validity of clinical trials. This is why randomised controlled trials (RCTs) lead every evidence hierarchy of therapeutic interventions. At the same time, there are controversies about the role of RCTs in health research. The article addresses the principle of randomisation and deals with some of the more prominent arguments against RCT.
Windeler
Jürgen
J
Medizinischer Dienst der Spitzenverbände der Krankenkassen, Essen. J.Windeler@MDS-ev.de
Antes
Gerd
G
Behrens
Johann
J
Donner-Banzhoff
Norbert
N
Lelgemann
Monika
M
D005858:Germany; D006801:Humans; D009042:Motivation; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000592:standards / Q000706:statistics & numerical data*; D012106:Research / Q000592:standards