title: Percentage of excess BMI lost correlates better with improvement of metabolic syndrome after Roux-en-Y gastric bypass in morbidly obese subjects: anthropometric indexes and gastric bypass.
abstract: BACKGROUND
  The metabolic syndrome (MS) is a complex disorder characterized by a number of cardiovascular risk factors usually associated with central fat deposition and insulin resistance. Many different medical treatments are available for MS, including bariatric surgery, which improves all risk factors. The present study aimed to evaluate, at the Clinic of Gastroenterology and Obesity Surgery (Brazil), the accuracy of different anthropometric indexes and their correlation with improvement of the MS factors in the postoperative (6-month) period.
  
  
  METHODS
  This was a retrospective study of 140 patients who had undergone gastric bypass. Most of the patients were women (79.3%). The mean body mass index was 44.17 kg/m(2). We evaluated the weight of the subjects, the presence of diabetes mellitus and hypertension as co-morbidities, and the biochemical parameters. The anthropometric indexes tested included the percentage of excess weight loss, amount lost in kilograms, difference in the body mass index, percentage of initial weight lost, percentage of excess body mass index lost (%EBL), and percentage of initial fat mass lost.
  
  
  RESULTS
  The %EBL had a Spearman's correlation coefficient of 0.55 (P <.0001) for the difference between the MS factors before and after Roux-en-Y gastric bypass. The receiver operating characteristic curve for the %EBL resulted in an area under the curve of 0.846 (P = 0.0001) and a sensitivity and specificity of 100% and 61.29%, respectively, for a cutoff value of 64.55%.
  
  
  CONCLUSIONS
  The %EBL was the best method to report weight loss and the improvement in MS in morbidly obese subjects after Roux-en-Y gastric bypass.
authors.affiliation: Member of Brazillian Society of Bariatric and Metabolic Surgery (Sociedade Brasileira de Cirurgia Bariátrica e Metabólica), São Paulo, Brazil.
authors.forename: Marçal
authors.initials: M
authors.lastname: Rossi
authors.forename: Ary
authors.initials: A
authors.lastname: Serpa Neto
authors.forename: Felipe Martin Bianco
authors.initials: FM
authors.lastname: Rossi
authors.forename: Rodrigo Dal Moro
authors.initials: RD
authors.lastname: Amarante
authors.forename: Geraldo Chaves
authors.initials: GC
authors.lastname: Alcântara
authors.forename: Renato Barretto Ferreira
authors.initials: RB
authors.lastname: da Silva
authors.forename: Paulo Fernando
authors.initials: PF
authors.lastname: Regina
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D005260:Female; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000517:prevention & control*; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology / Q000601:surgery*; D012372:ROC Curve; D012044:Regression Analysis; D012074:Remission Induction; D012189:Retrospective Studies; D015431:Weight Loss