title: Estrogenic activity of fractionate landfill leachate.
abstract: Dissolved organic matter (DOM) in leachate samples collected at Laogang Sanitary Landfill in Shanghai, China were fractionated using size exclusion chromatography and were characterized using estrogen receptor-alpha competitor screening assay as toxicity activity index. The estrogen activity of leachate was determined mainly by the hydrophobic acid DOM with moderate MW (3000-14,000 Da) and low MW (<630 Da) and with high aromaticity and fluorophores of possibly pyrenyl characteristics. Landfilling for up to seven years or oxic storage for one month degraded a few of these estrogens. Aerobic SBR treatments effectively degraded the hydrophobic estrogens, but rarely degraded the hydrophilic estrogens.
authors.affiliation: State Key Laboratory of Pollution Control and Resources Reuse, Tongji University, Shanghai 200092, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Cheng-Hsuan
authors.initials: CH
authors.lastname: Chang
authors.forename: Fan
authors.initials: F
authors.lastname: Lü
authors.forename: Duu-Jong
authors.initials: DJ
authors.lastname: Lee
authors.forename: Pin-Jing
authors.initials: PJ
authors.lastname: He
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Shao
authors.forename: Ay
authors.initials: A
authors.lastname: Su
mesh_terms: D001667:Binding, Competitive; D002681:China; D002850:Chromatography, Gel; D002947:Cities; D047628:Estrogen Receptor alpha / Q000378:metabolism; D004967:Estrogens / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity; D057927:Hydrophobic and Hydrophilic Interactions; D008970:Molecular Weight; D012037:Refuse Disposal; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity
chemical_list: D047628:Estrogen Receptor alpha; D004967:Estrogens; D014874:Water Pollutants, Chemical