title: Quality of life after on-pump and off-pump coronary artery bypass grafting surgery.
abstract: BACKGROUND
  Coronary artery bypass grafting techniques without using cardiopulmonary bypass (off-pump CABG) result in less systemic damage, less clinical complications, less time spent in the intensive care unit, and shorter hospital stays, thereby raising the perspective of improved quality of life (QOL) for patients.
  
  
  OBJECTIVE
  To assess quality of life in patients who underwent on-pump and off-pump CABG.
  
  
  METHODS
  The Short-Form Health Survey (SF-36) Questionnaire was administered to patients with stable multivessel coronary artery disease (CAD) and preserved ventricular function before and at six and 12 months after surgery.
  
  
  RESULTS
  Between January 2002 and December 2006, a total of 202 patients were randomized to either on-pump or off-pump CABG. Demographic, clinical, laboratory, and angiographic characteristics were similar in both groups. One hundred and five patients underwent off-pump CABG and 97 underwent on-pump CABG. In the postoperative course, 22 patients had myocardial infarction, 29 reported angina, one was reoperated, and three experienced stroke. No patient died. Quality of life, as measured by the SF-36 questionnaire, was shown to be similar in both groups regarding physical and mental components. However, male patients showed a significant improvement in physical functioning and role limitations due to physical problems. Also, a large number of patients in both groups returned to work.
  
  
  CONCLUSIONS
  Progressive enhancement in quality of life and early return to work were observed for all patients, regardless of the surgical technique used. Save for a greater improvement in physical functioning and role limitations due to physical problems experienced by male patients, no statistically significant differences were found in the other domains between groups.
authors.affiliation: Instituto do Coração do Hospital do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
authors.forename: Celia R S R
authors.initials: CR
authors.lastname: Nogueira
authors.forename: Whady
authors.initials: W
authors.lastname: Hueb
authors.forename: Myrthes E
authors.initials: ME
authors.lastname: Takiuti
authors.forename: Priscyla B M A
authors.initials: PB
authors.lastname: Girardi
authors.forename: Teryo
authors.initials: T
authors.lastname: Nakano
authors.forename: Fábio
authors.initials: F
authors.lastname: Fernandes
authors.forename: Felipe da S
authors.initials: Fda S
authors.lastname: Paulitsch
authors.forename: Aécio F T
authors.initials: AF
authors.lastname: Góis
authors.forename: Neuza H M
authors.initials: NH
authors.lastname: Lopes
authors.forename: Noedir A
authors.initials: NA
authors.lastname: Stolf
mesh_terms: D000787:Angina Pectoris / Q000175:diagnosis / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods*; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects; D003324:Coronary Artery Disease / Q000601:surgery*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology; D011788:Quality of Life; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome