title: Survival of three nonocclusive mesenteric ischemia patients following early diagnosis by multidetector row computed tomography and prostaglandin E1 treatment.
abstract: Nonocclusive mesenteric ischemia (NOMI) is an acute mesenteric circulatory disorder which is characterized by spasm and narrowing of the arterial branches. In contrast to occlusive disease, early diagnosis of NOMI is difficult because of its mild symptoms, thus resulting in a high mortality rate. In this study, we report three cases who survived NOMI because of early diagnosis by multidetector row computed tomography and immediate treatment with prostaglandin E1, which is known to improve blood flow by relaxing vascular smooth muscle. We conclude that early diagnosis and treatment of NOMI with prostaglandin E1 considerably improves the prognosis of this disease.
authors.affiliation: Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata. kenya-k@med.niigata-u.ac.jp
authors.forename: Kenya
authors.initials: K
authors.lastname: Kamimura
authors.forename: Akihiko
authors.initials: A
authors.lastname: Oosaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Sugahara
authors.forename: Shigeki
authors.initials: S
authors.lastname: Mori
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000527:Alprostadil / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D008297:Male; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging* / Q000187:drug effects; D008875:Middle Aged; D013534:Survival; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000527:Alprostadil