Botulinum toxin type A--treatment of a patient with multiple cutaneous piloleiomyomas.
BACKGROUND
Treatment of multiple cutaneous piloleiomyomas which are rare, frequently painful, benign tumors originating from the arrector pilorum muscle of hair follicles is difficult.


OBJECTIVE
To determine the efficiency of botulinum toxin type A (BT-A) treatment for pain relief of cutaneous piloleiomyomas.


METHODS
A patient with multiple painful piloleiomyomas was treated with local injections of 200 units of BT-A.


RESULTS
There was a rapid and sustained decrease in pain. Treatment was repeated every 3 months for 2 years with the same efficacy.


CONCLUSIONS
BT-A may be a promising new treatment option for multiple painful cutaneous piloleiomyomas.
Sifaki
Maria K
MK
Department of Dermatology, Faculty of Medicine, University of Crete, Heraklion, Greece.
Krueger-Krasagakis
Sabine
S
Koutsopoulos
Anastasios
A
Evangelou
Georgios I
GI
Tosca
Androniki D
AD
D000368:Aged; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D006197:Hair; D006801:Humans; D015552:Injections, Intralesional; D018231:Leiomyomatosis / Q000188:drug therapy*; D008297:Male; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A