Synthesis of (+/-) homoisoflavanone and corresponding homoisoflavane.
The total synthesis of racemic 3-(4'-methoxybenzyl)-7,8-methylenedioxy-chroman-4-one, a homoisoflavanone with antimycobacterial activity isolated recently from Chlorophytum inornatum, was described. During this research, the first approach for the conversion of homoisoflavonoids into homoisoflavanes was also developed.
Zhang
Liang
L
Department of Medicinal Chemistry, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
Zhang
Wei-Ge
WG
Kang
Jian
J
Bao
Kai
K
Dai
Yi
Y
Yao
Xin-Sheng
XS
D007529:Isoflavones / Q000138:chemical synthesis*; D015394:Molecular Structure
D007529:Isoflavones