title: Effect of methylenetetrahydrofolate reductase and thymidylate synthase enhancer region polymorphisms on the risk of idiopathic recurrent spontaneous abortion in a Korean population.
abstract: Previous studies reported an association of methylenetetrahydrofolate reductase (MTHFR) polymorphisms and recurrent spontaneous abortion, whereas no studies are available for the association with thymidylate synthase enhancer region (TSER) genotypes. Mutations of MTHFR and TSER are not likely significant risk factors of idiopathic recurrent spontaneous abortion in Korean women.
authors.affiliation: Institute for Clinical Research, Bundang CHA General Hospital, College of Medicine, Pochon CHA University, Seongnam, South Korea.
authors.forename: Jeehyeon
authors.initials: J
authors.lastname: Bae
authors.forename: Dong Hee
authors.initials: DH
authors.lastname: Choi
authors.forename: Myung Seo
authors.initials: MS
authors.lastname: Kang
authors.forename: Sun Hee
authors.initials: SH
authors.lastname: Cha
authors.forename: Doyeun
authors.initials: D
authors.lastname: Oh
authors.forename: Nam Keun
authors.initials: NK
authors.lastname: Kim
mesh_terms: D000022:Abortion, Spontaneous / Q000208:ethnology* / Q000235:genetics*; D000328:Adult; D016022:Case-Control Studies; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006801:Humans; D007723:Korea; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012008:Recurrence; D012307:Risk Factors; D013940:Thymidylate Synthase / Q000235:genetics*
chemical_list: D042965:Methylenetetrahydrofolate Reductase (NADPH2); D013940:Thymidylate Synthase