[The effects of antioxidants on the reflex from an eye-ground and electric activity of retina during intravitreal haemorrhage].
The object of investigation was to study the reflex from an eye-ground, the character of the disorder of electric activity of retina during the experimental vitreous haemorrhage and the possibility of correction of these alterations by the antioxidants. The research was conducted on 5 month 300 chinchilla rabbits of male sex, weight 2.8-3.2 kg. The phenosan kali, superoxidedismutase (SOD), catalasa, "Hemaza", ditikarbomat natrium (DTKN), mannitol, tocopherol acetate, deferooxamin were used. The rabbits treated with the antioxidants complex and "Hemasa" showed the best dynamic of the restoration of the ophthalmological conditions. It was found that, vitreous haemorrhage considerably damaged the formation of ERG. Separate application of antioxidants: phenosan kali, SOD and mannitol restore the amplitude of ERG retina during intravitreal haemorrhage, not influencing the temporal parameters. The application of antioxidants complex considerably restores the amplitude characteristics, becoming close to the norm, not influencing the time of ERG parameters development.
Guliyeva
U
U
Z. Aliyeva Scientific-research Institute of the Eye Diseases, Baku, Republic of Azerbaijan.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D003676:Deferoxamine / Q000494:pharmacology; D008297:Male; D010666:Phenylpropionates / Q000494:pharmacology*; D011817:Rabbits; D012018:Reflex / Q000187:drug effects*; D012160:Retina / Q000187:drug effects*; D017262:Siderophores / Q000494:pharmacology; D014823:Vitreous Hemorrhage / Q000503:physiopathology*
D000975:Antioxidants; D010666:Phenylpropionates; D017262:Siderophores; D003676:Deferoxamine; C047854:fenozan