title: Impact of progressive resistance training on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials.
abstract: OBJECTIVE
  Given the discrepant findings of progressive resistance training (PRT) on lipids and lipoproteins in adults, we used the meta-analytic approach to examine this issue.
  
  
  METHODS
  Randomized controlled trials > or =4 weeks dealing with the effects of PRT on lipids and lipoproteins in adult humans > or =18 years of age and published between January 1, 1955 and July 12, 2007 were included. Primary outcomes included total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). A random-effects model was used for analysis with data reported as means and 95% confidence intervals.
  
  
  RESULTS
  Twenty-nine studies representing 1329 men and women (676 exercise, 653 control) were included. Statistically significant improvements were found for TC (-5.5 mg/dl, -9.4 to -1.6), TC/HDL-C (-0.5, -0.9 to -0.2), non-HDL-C (-8.7 mg/dl, -14.1 to -3.3), LDL-C (-6.1 mg/dl, -11.2 to -1.0) and TG (-8.1 mg/dl, -14.5 to -1.8) but not HDL-C (0.7 mg/dl, -1.2 to 2.6). Changes were equivalent to -2.7%, 1.4%, -11.6%, -5.6%, -4.6%, and -6.4%, respectively, for TC, HDL-C, TC/HDL-C, non-HDL-C, LDL-C, and TG.
  
  
  CONCLUSIONS
  Progressive resistance training reduces TC, TC/HDL-C, non-HDL-C, LDL-C and TG in adults.
authors.affiliation: School of Medicine, Department of Community Medicine, West Virginia University, Morgantown, 26506-9190, USA. gkelley@hsc.wvu.edu
authors.forename: George A
authors.initials: GA
authors.lastname: Kelley
authors.forename: Kristi S
authors.initials: KS
authors.lastname: Kelley
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008055:Lipids / Q000096:biosynthesis*; D008074:Lipoproteins / Q000096:biosynthesis*; D008297:Male; D016032:Randomized Controlled Trials as Topic; D055070:Resistance Training; D055815:Young Adult
chemical_list: D008055:Lipids; D008074:Lipoproteins