Further evidence of spontaneous cure in human Chagas disease.
An acute case of Chagas disease was studied in 1944, with clinical and laboratory follow-up until 2007, in Bambuí, Minas Gerais, Brazil. A five-year-old girl living in a rural hut that was highly infested with Triatoma infestans presented a febrile clinical condition compatible with the acute form of trypanosomiasis. She presented a positive thick blood smear, but never again showed serological and/or parasitological evidence of Trypanosoma cruzi infection, on several occasions. This patient never received any specific treatment and, to this day, she remains completely asymptomatic, with normal findings from clinical, electrocardiographic, X-ray and echocardiographic examinations.
Dias
João Carlos Pinto
JC
Fundação Oswaldo Cruz, Belo Horizonte, MG. jcpdias@cpqrr.fiocruz.br
Dias
Emmanuel
E
Martins-Filho
Olindo Assis
OA
Filho
Olindo M
OM
Vitelli-Avelar
Danielle
D
Correia
Dalmo
D
Lages
Eliane
E
Prata
Aluízio
A
D000208:Acute Disease; D000368:Aged; D014355:Chagas Disease; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D012075:Remission, Spontaneous