Pathologic features of renal cortical tumors.
Our better understanding of the morphologic spectrum of renal cortical tumors has resulted in a clinically more relevant classification of these tumor types. We now recognize that "granular cell" and "sarcomatoid" renal cell carcinoma are only nonspecific descriptors, and that such features are seen in a variety of types of renal tumors. The authors believe that the recently gained knowledge about molecular-driven antigen expression will play an important role in the characterization, development, and evaluation of targeted therapies in kidney cancer in the coming years.
Tickoo
Satish K
SK
Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA. tickoos@mskcc.org
Gopalan
Anuradha
A
D018262:Adenocarcinoma, Clear Cell / Q000235:genetics / Q000473:pathology; D000231:Adenocarcinoma, Papillary / Q000235:genetics / Q000473:pathology; D000238:Adenoma, Chromophobe / Q000235:genetics / Q000473:pathology; D018249:Adenoma, Oxyphilic / Q000235:genetics / Q000473:pathology; D018276:Carcinoma, Medullary / Q000235:genetics / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000235:genetics / Q000473:pathology; D020022:Genetic Predisposition to Disease; D006801:Humans; D007672:Kidney Cortex / Q000473:pathology*; D052177:Kidney Diseases, Cystic / Q000473:pathology; D007680:Kidney Neoplasms / Q000145:classification / Q000235:genetics / Q000473:pathology*; D007685:Kidney Tubules, Collecting / Q000473:pathology; D009367:Neoplasm Staging / Q000379:methods; D014178:Translocation, Genetic