title: Paecilomyces lilacinus peritonitis complicating peritoneal dialysis cured by oral voriconazole and terbinafine combination therapy.
abstract: Fungal peritonitis (FP) is a serious complication in patients on continuous ambulatory peritoneal dialysis (CAPD). We report a case of CAPD-related FP caused by Paecilomyces lilacinus in a 15-year-old uraemic boy. The infection was successfully treated by combination therapy consisting of oral voriconazole and terbinafine, which has not been previously reported in the treatment of FP.
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Brian Pin-Hsuan
authors.initials: BP
authors.lastname: Chang
authors.affiliation: Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Pei-Lun
authors.initials: PL
authors.lastname: Sun
authors.affiliation: Department of Pediatrics, Taipei Medical University, Taipei, Taiwan.|Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Fu-Yuan
authors.initials: FY
authors.lastname: Huang
authors.affiliation: Department of Pediatrics, Taipei Medical University Wan-Fang Hospital, Taipei, Taiwan.
authors.forename: Tsuen-Chiuan
authors.initials: TC
authors.lastname: Tsai
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chun-Chen
authors.initials: CC
authors.lastname: Lin
authors.affiliation: Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Ming-Dar
authors.initials: MD
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Yee-Chun
authors.initials: YC
authors.lastname: Chen
authors.affiliation: Department of Pediatric Surgery, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Jin-Cherng
authors.initials: JC
authors.lastname: Sheu
authors.affiliation: Department of Pediatrics, Taipei Medical University, Taipei, Taiwan.|Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Jeng-Daw
authors.initials: JD
authors.lastname: Tsai
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use; D010143:Paecilomyces / Q000187:drug effects / Q000302:isolation & purification*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use; D000077291:Terbinafine; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D011743:Pyrimidines; D014230:Triazoles; D000077291:Terbinafine; D065819:Voriconazole