title: Successful treatment of ligneous gingivitis with warfarin.
abstract: Ligneous gingivitis is a rare condition characterized by inflammation and nodular gingival enlargement secondary to fibrin deposits in the gingival that results from plasminogen deficiency. Several therapeutic approaches have been used with limited success. We report a case of a patient with homozygous plasminogen deficiency and ligneous gingivitis that was initially refractory to local care and systemic antibiotics, but later improved with the addition of warfarin.
authors.affiliation: Department of Medicine, Hematology/Oncology Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. gfine@bidmc.harvard.edu
authors.forename: Gregg
authors.initials: G
authors.lastname: Fine
authors.forename: Kenneth
authors.initials: K
authors.lastname: Bauer
authors.forename: Maha
authors.initials: M
authors.lastname: Al-Mohaya
authors.forename: Sook-Bin
authors.initials: SB
authors.lastname: Woo
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D020147:Coagulation Protein Disorders / Q000150:complications*; D005260:Female; D005891:Gingivitis / Q000188:drug therapy* / Q000209:etiology*; D006720:Homozygote; D006801:Humans; D008875:Middle Aged; D010958:Plasminogen / Q000172:deficiency*; D002575:Uterine Cervicitis / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use*
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D010958:Plasminogen