A case of malignant primary non-Hodgkin's lymphoma in skeletal muscle treated by exclusive chemotherapy.
Malignant non-Hodgkin's lymphoma (MNHL) is a frequent tumour but a primary intra-muscular location is exceptional. Standard treatment combines wide surgical removal with chemotherapy and radiotherapy. The functional consequences of this large excision are sometimes very unsatisfactory. We report the case of an intra-muscular MNHL of the posterior and internal part of the thigh. The diagnostic was established thanks to selective biopsies. The treatment was purely medical and conservative with chemotherapy after a multidisciplinary oncological discussion. Three years after the treatment, the general state of health is excellent with no signs of local or remote recurrence.
Laffosse
Jean-Michel
JM
Service Chirurgie Orthopédique et Traumatologique, CHU Rangueil, 1 avenue Jean Poulhès, 31059 Toulouse, France. jean-michel.laffosse@wanadoo.fr
Gomez-Brouchet
Anne
A
Molinier
François
F
Chiron
Philippe
P
Roché
Henri
H
Puget
Jean
J
D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D018572:Disease-Free Survival; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D013848:Thigh / Q000473:pathology; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone