title: Drug discovery: new models for industry-academic partnerships.
abstract: The re-focusing of pharmaceutical industry research away from early discovery activities is stimulating the development of novel models of drug discovery, notably involving academia as a 'front end'. In this article the authors explore the drivers of change, the role of new entrants (universities with specialised core facilities) and novel partnership models. If they are to be sustainable and deliver, these new models must be flexible and properly funded by industry or public funding, rewarding all partners for contributions. The introduction of an industry-like process and experienced management teams signals a revolution in discovery that benefits society by improving the value gained from publicly funded research.
authors.affiliation: Drug Discovery Centre and Business Development, Imperial College London SW7 2AZ, UK. c.tralau@imperial.ac.uk
authors.forename: Cathy J
authors.initials: CJ
authors.lastname: Tralau-Stewart
authors.forename: Colin A
authors.initials: CA
authors.lastname: Wyatt
authors.forename: Dominique E
authors.initials: DE
authors.lastname: Kleyn
authors.forename: Alex
authors.initials: A
authors.lastname: Ayad
mesh_terms: D000818:Animals; D003299:Cooperative Behavior; D055808:Drug Discovery / Q000191:economics / Q000458:organization & administration*; D004345:Drug Industry / Q000191:economics / Q000458:organization & administration*; D005380:Financing, Government; D006801:Humans; D017146:Models, Organizational; D012109:Research Support as Topic; D014495:Universities / Q000458:organization & administration*