title: Antioxidant therapy in Alzheimer's disease: theory and practice.
abstract: Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.
authors.affiliation: Department of Biology, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, USA.
authors.forename: Gjumrakch
authors.initials: G
authors.lastname: Aliev
authors.forename: Mark E
authors.initials: ME
authors.lastname: Obrenovich
authors.forename: V Prakash
authors.initials: VP
authors.lastname: Reddy
authors.forename: Justin C
authors.initials: JC
authors.lastname: Shenk
authors.forename: Paula I
authors.initials: PI
authors.lastname: Moreira
authors.forename: Akihiko
authors.initials: A
authors.lastname: Nunomura
authors.forename: Xiongwei
authors.initials: X
authors.lastname: Zhu
authors.forename: Mark A
authors.initials: MA
authors.lastname: Smith
authors.forename: George
authors.initials: G
authors.lastname: Perry
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology; D016166:Free Radical Scavengers / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers