Directed epoxidation of cyclohexa-1,4-dienes-stereoselective formation of up to six contiguous stereogenic centres.
Epoxidation/cyclisation of cyclohexa-1,4-dienes containing pendant hydroxyl groups provides stereocontrolled access to highly-functionalised reduced benzol[b]furan derivatives.
Butters
Michael
M
AstraZeneca Process R & D Avlon/Charnwood, Avlon Works, Severn Road, Hallen, Bristol, UK, BS10 7ZE.
Beetstra
Dirk J
DJ
Elliott
Mark C
MC
Hill-Cousins
Joseph
J
Kariuki
Benson M
BM
D053138:Cyclohexenes / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D053138:Cyclohexenes; D004852:Epoxy Compounds; C048401:1,4-cyclohexadiene