title: Chemical composition and in vitro antimicrobial activity of the essential oils of two Helichrysum species from Tanzania.
abstract: The chemical composition of the essential oils obtained from the aerial parts of Helichrysum cymosum and H. fulgidum, from Tanzania, were analyzed by GC and GC/MS. A total of sixty-five compounds, representing 92.4% and 88.2% of the two oils, respectively, were identified. trans-Caryophyllene, caryophyllene oxide, beta-pinene, p-cymene, spathulenol and beta-bourbonene were found to be the main components. Furthermore, the oils were tested against six gram (+/-) bacteria and three pathogenic fungi. It was found that the oil of H. fulgidum exhibited significant antimicrobial activity, while the oil of H. cymosum was not active at all.
authors.affiliation: Laboratory of Pharmacognosy, Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Bougatsos
authors.forename: Olipa
authors.initials: O
authors.lastname: Ngassapa
authors.forename: Deborah K B
authors.initials: DK
authors.lastname: Runyoro
authors.forename: Ioanna B
authors.initials: IB
authors.lastname: Chinou
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002849:Chromatography, Gas; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D036562:Helichrysum / Q000737:chemistry* / Q000145:classification; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013636:Tanzania
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile