Endodontic surgery with and without inserts of bioactive glass PerioGlas--a clinical and radiographic follow-up.
OBJECTIVE
This study evaluated the use of bioactive glass, PerioGlas, after retrograde filling with Super EBA cement in the treatment of periapical bone destruction.


METHODS
Healing outcomes were followed up after endodontic surgery in 186 teeth. Outcomes were divided into two groups according to follow-up time: short- and long-term. The EBA group (n = 110) underwent endodontic surgery and retrograde filling with EBA cement. In the EBA + PerioGlas group (n = 76), PerioGlas was embedded in the bone cavity after retrograde filling.


RESULTS
The success rate in the EBA + PerioGlas group was 72% compared with 56% in the Super EBA group at the short-term follow-up and 74% and 84%, respectively, at the long-term follow-up. Healing of periapical bone destruction classified as uncertain at the short-term follow-up was considered successful in two out of three cases at the long-term follow-up.


CONCLUSIONS
This study found that PerioGlas as bone substitute did not significantly improve endodontic healing outcome.
Pantchev
Alexander
A
Department of Oral Rehabilitation/Endodontics, Central Hospital, SE-721 89, Västerås, Sweden. alexander.pantchev@ltv.se
Nohlert
Eva
E
Tegelberg
Ake
A
D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D001861:Bone Regeneration / Q000502:physiology; D002516:Ceramics; D003759:Dental Implantation, Endosseous, Endodontic / Q000379:methods*; D017220:Dentin-Bonding Agents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011859:Radiography; D012189:Retrospective Studies; D012387:Root Canal Filling Materials; D014945:Wound Healing / Q000502:physiology
D001672:Biocompatible Materials; C022107:Bioglass; D017220:Dentin-Bonding Agents; D012387:Root Canal Filling Materials; C084074:Super EBA