Biomimetic self-condensation of malonates mediated by nucleosides.
Nucleoside mediated Claisen condensation of malonates has been achieved under biomimetic weak acid conditions, pH 3or 4, 0.15 M NaCl, and 0.125 M Mg(2+). The result illustrates the catalyzing property of end-nucleosides of t-RNA in the RNA world.
Ji
Qi
Q
Center for Biological NMR, Department of Chemistry, Texas A&M University, College Station, TX 77843, USA.
Williams
Howard J
HJ
Roessner
Charles A
CA
Scott
A Ian
AI