Proline-catalyzed highly enantioselective and anti-selective Mannich reaction of unactivated ketones: synthesis of chiral alpha-amino acids.
Hahn
Björn T
BT
Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
Fröhlich
Roland
R
Harms
Klaus
K
Glorius
Frank
F
D000596:Amino Acids / Q000138:chemical synthesis*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D010780:Photogrammetry; D011392:Proline / Q000737:chemistry*
D000596:Amino Acids; D007659:Ketones; D011392:Proline