title: [Ashy dermatosis: clinico-pathological associations in two cases].
abstract: Case 1. A 54 year old woman affected by chronic asthmatic bronchitis from the age of 11 years and ulcerous recto-colitis from 15 years, presented several erythematous-violaceous macules from the trunk including abdominal region to all skin surface except the face. Case 2. A 17 year old woman presented a similar hyperpigmentation in the same areas. In both patients histology showed a thin epidermis with vacuolar changes of basal layer and apoptotic bodies and melanophages rich in melanosomes in the papillary dermis. Our diagnosis was Ashy dermatitis. Clinico-pathological correlations and treatment options are discussed.
authors.affiliation: Clinica Dermatologica Università di Roma Tor Vergata, Roma, Italia. isabella.carboni@uniroma2.it
authors.forename: I
authors.initials: I
authors.lastname: Carboni
authors.forename: A
authors.initials: A
authors.lastname: Costanzo
authors.forename: E
authors.initials: E
authors.lastname: Campione
authors.forename: E J
authors.initials: EJ
authors.lastname: Paternò
authors.forename: S
authors.initials: S
authors.lastname: Chimenti
mesh_terms: D000293:Adolescent; D000975:Antioxidants / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology*; D005121:Extremities / Q000473:pathology; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D009824:Ointments; D012867:Skin / Q000098:blood supply / Q000473:pathology; D013909:Thorax / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D009824:Ointments