title: Ten-year results of a randomized clinical trial of laparoscopic total fundoplication with or without division of the short gastric vessels.
abstract: BACKGROUND
  Total fundoplication is the most common antireflux operation and can be performed with or without division of the short gastric vessels. There seems to be no difference in short-term outcomes with either approach. The aim of the study was to determine whether there were the long-term differences (after 10 years).
  
  
  METHODS
  Ninety-nine patients were enrolled in the study. Short gastric vessels were divided in 52 patients (group 1) and left intact in 47 (group 2). Ten patients were lost to follow-up and seven patients died, leaving 42 patients for analysis in group 1 and 40 in group 2. All patients were evaluated by standardized quality of life questionnaires.
  
  
  RESULTS
  Three patients underwent reoperation within 5 years. Thirty-eight of 42 patients with a completely mobilized fundus reported no reflux symptoms, compared with 31 of 40 patients with intact vessels. There were no differences between the groups in other symptoms reflecting post-fundoplication complaints and quality of life outcomes.
  
  
  CONCLUSIONS
  When total fundoplication is performed it makes no difference whether the fundus is mobilized or not. Both types of repair provide lasting control of reflux.
authors.affiliation: Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Mardani
authors.forename: L
authors.initials: L
authors.lastname: Lundell
authors.forename: H
authors.initials: H
authors.lastname: Lönroth
authors.forename: J
authors.initials: J
authors.lastname: Dalenbäck
authors.forename: C
authors.initials: C
authors.lastname: Engström
mesh_terms: D000863:Antacids / Q000627:therapeutic use; D001808:Blood Vessels; D002908:Chronic Disease; D003680:Deglutition Disorders / Q000209:etiology; D005260:Female; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D011788:Quality of Life; D012086:Reoperation; D013270:Stomach / Q000098:blood supply / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000863:Antacids