title: Cytotoxic effects of halogen- and light-emitting diode-cured compomers on human pulp fibroblasts.
abstract: OBJECTIVE
  The aim of this study was to determine the cytotoxic effects of three different compomers (Dyract AP, Compoglass, and Hytac) cured using a halogen light-curing unit (LCU) and a light-emitting diode (LED) LCU on human pulp fibroblasts.
  
  
  METHODS
  Specimens of three compomers were added to human pulp fibroblast cultures. Cytotoxicity was evaluated over 96 h using the agar overlay method.
  
  
  RESULTS
  All three compomers tested were found to be moderately cytotoxic to human pulp fibroblasts, regardless of whether they were cured using halogen or LED LCUs. The decolorization zone of Hytac was significantly larger than those of the other compomers tested (P < 0.05). Dyract AP and Compoglass specimens showed greater decolorization when cured with LED than with halogen LCUs (P < 0.05).
  
  
  CONCLUSIONS
  Compomers are potentially toxic to human pulp fibroblasts, and the type of curing unit may affect compomer toxicity.
authors.affiliation: Department of Pediatric Dentistry, Faculty of Dentistry, University of Ondokuz Mayis, Samsun, Turkey. etunc@omu.edu.tr
authors.forename: Emine Sen
authors.initials: ES
authors.lastname: Tunç
authors.forename: Levent
authors.initials: L
authors.lastname: Ozer
authors.forename: Saziye
authors.initials: S
authors.lastname: Sari
authors.forename: Serap
authors.initials: S
authors.lastname: Cetiner
mesh_terms: D018929:Cell Culture Techniques; D002470:Cell Survival; D002478:Cells, Cultured; D004396:Coloring Agents; D020770:Compomers / Q000528:radiation effects / Q000633:toxicity*; D003188:Composite Resins / Q000528:radiation effects / Q000633:toxicity; D055117:Curing Lights, Dental / Q000145:classification*; D003764:Dental Materials / Q000528:radiation effects / Q000633:toxicity*; D005347:Fibroblasts / Q000187:drug effects*; D005840:Gentian Violet; D005899:Glass Ionomer Cements / Q000528:radiation effects / Q000633:toxicity; D006801:Humans; D008422:Materials Testing; D013997:Time Factors
chemical_list: D004396:Coloring Agents; C105428:Compoglass; D020770:Compomers; D003188:Composite Resins; D003764:Dental Materials; C088486:Dyract; D005899:Glass Ionomer Cements; C105429:hytac; D005840:Gentian Violet