title: Transudates in malignancy: still a role for pleural fluid.
abstract: BACKGROUND
  The aims of this study were to determine the distribution of transudates and exudates among pathologically proven malignant pleural effusions, and to demonstrate the necessity for cytologic studies in patients with a transudative effusion.
  
  
  METHODS
  This study is a retrospective review of all subjects diagnosed with malignant or paramalignant pleural effusion over a 10-year period at a tertiary hospital. The study included 67 subjects with malignant mesothelioma, 45 subjects with metastatic disease, and 36 subjects with paramalignant effusions.
  
  
  RESULTS
  There were 55 female and 93 male subjects; the mean age of the sample was 62 years. Malignant pleural effusions were transudative in 1.5% of malignant mesotheliomas, 6.8% of metastatic diseases, and 11.1% of paramalignant effusions.
  
  
  CONCLUSIONS
  Cytological examination of pleural fluid in patients with unexplained transudative effusion is essential to rule out malignant processes.
authors.affiliation: Canakkale State Hospital, Department of Chest Diseases, Canakkale, Turkey. tefeoglu@gmail.com
authors.forename: Tanseli E
authors.initials: TE
authors.lastname: Gonlugur
authors.forename: Ugur
authors.initials: U
authors.lastname: Gonlugur
mesh_terms: D015331:Cohort Studies; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D016066:Pleural Effusion, Malignant / Q000473:pathology*; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary; D012189:Retrospective Studies