title: Intercellular junctions: actin the PARt.
abstract: Several distinct polarity complexes participate in the assembly of intercellular junctions. Two studies showing that some of the same polarity complexes are essential regulators of continued junctional integrity lead to a new appreciation of the relationships between assembly and maintenance of intercellular junctions and highlight unappreciated roles for endocytosis in these processes.
authors.affiliation: Department of Pathology, University of Chicago, Chicago, IL 60637, USA.
authors.forename: Le
authors.initials: L
authors.lastname: Shen
authors.forename: Jerrold R
authors.initials: JR
authors.lastname: Turner
mesh_terms: D000199:Actins / Q000378:metabolism; D022005:Adherens Junctions / Q000378:metabolism*; D000818:Animals; D015820:Cadherins / Q000378:metabolism*; D004330:Drosophila / Q000378:metabolism; D029721:Drosophila Proteins / Q000378:metabolism; D004705:Endocytosis; D011493:Protein Kinase C / Q000378:metabolism; D020764:cdc42 GTP-Binding Protein / Q000378:metabolism
chemical_list: D000199:Actins; D015820:Cadherins; D029721:Drosophila Proteins; C115015:PKC-3 protein; C532584:Par-6 protein, Drosophila; D011493:Protein Kinase C; D020764:cdc42 GTP-Binding Protein