title: No evidence of bias in the process of publication of diagnostic accuracy studies in stroke submitted as abstracts.
abstract: OBJECTIVE
  There is little empirical evidence on publication bias in diagnostic test accuracy studies. We evaluated the proportion of abstracts presented at international stroke meetings, which were later published in full, and investigated which study features characterized publication.
  
  
  METHODS
  We reviewed all diagnostic abstracts presented at two international stroke conferences between 1995 and 2004. We assessed the characteristics and findings of the identified abstracts. We identified full publications through electronic databases and by contacting the authors. Determinants of publication were assessed by Cox regression.
  
  
  RESULTS
  Seventy-six percent (121 out of 160) of identified abstracts were subsequently published in full. Sixty-two percent were published within 24 months of presentation. The median time to publication was 16 months. Assessment of interobserver agreement between test readers was a significant predictor of full publication (P=0.02). No other study characteristic (including clinical utility of results, multicenter status, or Youden's index) was predictive.
  
  
  CONCLUSIONS
  We found no clear evidence of bias in the publication process that occurs after abstract acceptance. We were unable to assess bias in abstract submission or acceptance. "Interobserver agreement" was the only characteristic statistically associated with publication. Clinical utility of results and other study characteristics did not predict publication. Diagnostic abstracts often did not report many relevant methodological aspects.
authors.affiliation: Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK. m.brazzelli@ed.ac.uk
authors.forename: Miriam
authors.initials: M
authors.lastname: Brazzelli
authors.forename: Stephanie C
authors.initials: SC
authors.lastname: Lewis
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Deeks
authors.forename: Peter A G
authors.initials: PA
authors.lastname: Sandercock
mesh_terms: D000043:Abstracting and Indexing / Q000592:standards*; D003226:Congresses as Topic / Q000592:standards*; D006801:Humans; D053208:Kaplan-Meier Estimate; D010506:Periodicals as Topic / Q000592:standards*; D017594:Publication Bias; D011643:Publishing / Q000592:standards*; D012107:Research Design; D020521:Stroke / Q000175:diagnosis*; D013997:Time Factors