title: Central corneal thickness in children with congenital cataract and children with surgical aphakia: a case-control study.
abstract: OBJECTIVE
  To measure the central corneal thickness (CCT) of children with congenital cataract and surgical aphakia.
  
  
  METHODS
  Children with congenital cataract or surgical aphakia were prospectively recruited and divided into four groups: unilateral cataract (group 1, n = 14), bilateral cataract (group 2, n = 17), unilateral aphakia (group 3, n = 32) and bilateral aphakia (group 4, n = 44). An age-, sex-, and race-matched control group of normal individuals was selected. Ultrasonic pachymetry was performed by the same observer.
  
  
  RESULTS
  The mean CCT of the control group was not significantly different from the normal (p = 0.747) and cataractous eyes of group 1 (p = 0.252). The mean CCTs of both eyes of group 2 were significantly higher than the control group (p<0.01). The mean CCT of the aphakic eyes in group 3 was significantly higher than the contralateral healthy eyes and control eyes (p<0.001). The mean CCTs of both eyes of group 4 were significantly higher than the control group (p<0.001). The mean CCT was significantly higher in aphakic eyes of groups 3 and 4 than in cataractous eyes of groups 1 and 2 (p<0.001).
  
  
  CONCLUSIONS
  Aphakic eyes due to congenital cataract show thicker corneas than normal phakic eyes. Aphakic eyes after congenital cataract extraction show thicker corneas than eyes with congenital cataracts, suggesting that the increase in CCT occurs postoperatively.
authors.affiliation: Department of Ophthalmology, University of Campinas, Campinas, SP, Brazil, R. Mario de Andrade, 201 casa 43, Campo Grande, MS 79032-260, Brazil. alvaro.lupinacci@gmail.com
authors.forename: A P C
authors.initials: AP
authors.lastname: Lupinacci
authors.forename: M L
authors.initials: ML
authors.lastname: da Silva Jordão
authors.forename: G
authors.initials: G
authors.lastname: Massa
authors.forename: C E L
authors.initials: CE
authors.lastname: Arieta
authors.forename: V P
authors.initials: VP
authors.lastname: Costa
mesh_terms: D000293:Adolescent; D001035:Aphakia / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D002386:Cataract / Q000151:congenital* / Q000000981:diagnostic imaging*; D002387:Cataract Extraction; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011184:Postoperative Period; D011446:Prospective Studies; D014463:Ultrasonography