Quality of life after on-pump and off-pump coronary artery bypass grafting surgery.
BACKGROUND
Coronary artery bypass grafting techniques without using cardiopulmonary bypass (off-pump CABG) result in less systemic damage, less clinical complications, less time spent in the intensive care unit, and shorter hospital stays, thereby raising the perspective of improved quality of life (QOL) for patients.


OBJECTIVE
To assess quality of life in patients who underwent on-pump and off-pump CABG.


METHODS
The Short-Form Health Survey (SF-36) Questionnaire was administered to patients with stable multivessel coronary artery disease (CAD) and preserved ventricular function before and at six and 12 months after surgery.


RESULTS
Between January 2002 and December 2006, a total of 202 patients were randomized to either on-pump or off-pump CABG. Demographic, clinical, laboratory, and angiographic characteristics were similar in both groups. One hundred and five patients underwent off-pump CABG and 97 underwent on-pump CABG. In the postoperative course, 22 patients had myocardial infarction, 29 reported angina, one was reoperated, and three experienced stroke. No patient died. Quality of life, as measured by the SF-36 questionnaire, was shown to be similar in both groups regarding physical and mental components. However, male patients showed a significant improvement in physical functioning and role limitations due to physical problems. Also, a large number of patients in both groups returned to work.


CONCLUSIONS
Progressive enhancement in quality of life and early return to work were observed for all patients, regardless of the surgical technique used. Save for a greater improvement in physical functioning and role limitations due to physical problems experienced by male patients, no statistically significant differences were found in the other domains between groups.
Nogueira
Celia R S R
CR
Instituto do Coração do Hospital do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Hueb
Whady
W
Takiuti
Myrthes E
ME
Girardi
Priscyla B M A
PB
Nakano
Teryo
T
Fernandes
Fábio
F
Paulitsch
Felipe da S
Fda S
Góis
Aécio F T
AF
Lopes
Neuza H M
NH
Stolf
Noedir A
NA
D000787:Angina Pectoris / Q000175:diagnosis / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods*; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects; D003324:Coronary Artery Disease / Q000601:surgery*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology; D011788:Quality of Life; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome