title: Deproteinized bovine bone versus beta-tricalcium phosphate in sinus augmentation surgery: a comparative histologic and histomorphometric study.
abstract: OBJECTIVE
  To compare the efficacy of 2 common materials in sinus augmentation surgery and to assess their contribution when enriched with autogenous bone.
  
  
  METHODS
  The prospective human study was performed in 48 sinus grafting operations using beta-tricalcium phosphate or deproteinized bovine bone (pure or mixed with 10% to 20% autogenous bone) or autogenous bone. Biopsy specimens were taken after 9 months. Statistical evaluation was done with a 2-sample t test (P < .05).
  
  
  RESULTS
  When autogenous bone was used, 49.2% +/- 3.1% of new bone was found, which is significantly higher than in all the other groups. A higher proportion (34.2% +/- 13.1%) of the new vital bone was found in the deproteinized bovine bone group, in comparison with the beta-tricalcium phosphate group (21.4% +/- 8.1%) and the beta-tricalcium phosphate composite graft group (24.0% +/- 6.6%; P < .05). No significant differences between single-component grafts and corresponding composite grafts were established.
  
  
  CONCLUSIONS
  Sinus augmentation with the aforementioned augmentation materials is a well-accepted procedure. However, autogenous bone alone was the best material. More new bone was found using deproteinized bovine bone than beta-tricalcium phosphate. The addition of 10% to 20% autogenous bone to the bone substitute did not significantly influence the new bone formation.
authors.affiliation: Department of Dentistry, Charles University in Prague, Faculty of Medicine, Hradec Kralove, Czech Republic. simunek@email.cz
authors.forename: Antonin
authors.initials: A
authors.lastname: Simunek
authors.forename: Dana
authors.initials: D
authors.lastname: Kopecka
authors.forename: Rakesh V
authors.initials: RV
authors.lastname: Somanathan
authors.forename: Shriharsha
authors.initials: S
authors.lastname: Pilathadka
authors.forename: Tomas
authors.initials: T
authors.lastname: Brazda
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation; D002130:Calcium Phosphates; D002417:Cattle; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000601:surgery*; D008875:Middle Aged; D008903:Minerals; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D002130:Calcium Phosphates; D008903:Minerals; C485817:beta-tricalcium phosphate