title: Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines.
abstract: Hetero-Diels-Alder reactions of 1,3-bis(silyloxy)-1,3-butadienes with arylsulfonylcyanides afforded a variety of 4-hydroxy-2-(arylsulfonyl)pyridines. Several derivatives show antimicrobial activity against Gram-positive bacteria.
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.
authors.forename: Ibrar
authors.initials: I
authors.lastname: Hussain
authors.forename: Mirza Arfan
authors.initials: MA
authors.lastname: Yawer
authors.forename: Michael
authors.initials: M
authors.lastname: Lalk
authors.forename: Ulrike
authors.initials: U
authors.lastname: Lindequist
authors.forename: Alexander
authors.initials: A
authors.lastname: Villinger
authors.forename: Christine
authors.initials: C
authors.lastname: Fischer
authors.forename: Peter
authors.initials: P
authors.lastname: Langer
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D002175:Candida / Q000187:drug effects; D003486:Cyanides / Q000138:chemical synthesis / Q000737:chemistry*; D003500:Cyclization; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D002070:Butadienes; D003486:Cyanides; D011725:Pyridines