Genetic association analysis with FAMHAP: a major program update.
FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data. Furthermore, weprovide an additional program runFamhap that allows users to start the same method repeatedly for varying sets of genetic markers. In addition, a platform-independent graphical user interface (GUI) was developed to simplify the usage of both FAMHAP and runFamhap. The runFamhap program greatly facilitates the application of FAMHAP to genome-wide association studies (GWAS) and supports flexible genome-wide haplotype analysis. As an example, we describe application to HapMap data.


BACKGROUND
The software is available at http://famhap.meb.uni-bonn.de
Herold
Christine
C
Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany. herold@imbie.meb.uni-bonn.de
Becker
Tim
T
D019295:Computational Biology / Q000379:methods*; D055106:Genome-Wide Association Study; D006239:Haplotypes; D006801:Humans; D012984:Software