title: International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations.
abstract: An international interlaboratory proficiency testing program for the measurement of antifungal drugs was initiated in 2007. This first round was limited to azole antifungals: fluconazole, itraconazole and hydroxyitraconazole, voriconazole, and posaconazole. The results demonstrate the need for and utility of an ongoing proficiency testing program to further improve the analytical methods for routine patient management and clinical research.
authors.affiliation: Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen University Centre for Infectious Diseases, Nijmegen, The Netherlands. R.Bruggemann@akf.umcn.nl
authors.forename: Roger J M
authors.initials: RJ
authors.lastname: Brüggemann
authors.forename: Daan J
authors.initials: DJ
authors.lastname: Touw
authors.forename: Rob E
authors.initials: RE
authors.lastname: Aarnoutse
authors.forename: Paul E
authors.initials: PE
authors.lastname: Verweij
authors.forename: David M
authors.initials: DM
authors.lastname: Burger
mesh_terms: D000935:Antifungal Agents / Q000097:blood*; D001393:Azoles / Q000097:blood; D001681:Biological Assay / Q000379:methods; D015725:Fluconazole / Q000097:blood; D006801:Humans; D017964:Itraconazole / Q000031:analogs & derivatives / Q000097:blood; D011743:Pyrimidines / Q000097:blood; D014230:Triazoles / Q000097:blood; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D011743:Pyrimidines; D014230:Triazoles; C084794:hydroxyitraconazole; D017964:Itraconazole; C101425:posaconazole; D015725:Fluconazole; D065819:Voriconazole