Familial membranous glomerulopathy, toxic exposure and/or genetic sensibility?
Membranous nephropathy rarely occurs as a familial disease. We report two siblings (brother and sister) who presented with nephrotic syndrome and many vascular complications. HLA identities and potential toxic exposure may be concurring in these cases.
Muller
C
C
Department of Nephrology, Hôpital Civil de Colmar, Avenue Rome, Colmar, France. clotilde-muller@hotmail.fr
Alenabi
F
F
Chantrel
F
F
Muller
S
S
Trivin
C
C
Faller
B
B
D000328:Adult; D015938:Complement Membrane Attack Complex / Q000276:immunology*; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D005919:Glomerular Filtration Rate / Q000502:physiology; D015433:Glomerulonephritis, Membranous / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D008297:Male
D015938:Complement Membrane Attack Complex; D003404:Creatinine