Description of three novel HLA-DRB3 alleles: DRB3*010105, DRB3*0112 and DRB3*0113.
This communication describes three novel DRB3 alleles whose exon 2 sequences are identical to that of DRB3*010102 except for a single nucleotide substitutions. Comparing with DRB3*010102, the sequence of DRB3*010105, DRB3*0112, and DRB3*0113 differ at codon 31 (TTC -> TTT), codon 84 (GGG -> CGG; Gly -> Arg), and codon 37 (TTC -> CTC; Phe -> Leu), respectively.
Lee
K W
KW
Hallym Institution for Genome Application, College of Medicine, Hallym University Sacred Heart Hospital, Hallym University, Dongan-Gu, Anyang, Korea. hlakw@hanmail.net
Jung
Y-A
YA
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics*; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics*; D059826:HLA-DRB3 Chains; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D006684:HLA-DR Antigens; D059826:HLA-DRB3 Chains; C538929:HLA-DRB3*0113; C538927:HLA-DRB3*01:01:05 antigen; C538928:HLA-DRB3*01:12 antigen