Two new isomeric alpha-tetralones from Pyrola calliantha.
Callianthones A ( 1) and B ( 2), a pair of new isomeric alpha-tetralones, together with a known alpha-tetralone ( 3) and four known flavonoids ( 4 - 7) were isolated from the 50 % EtOH extract of Pyrola calliantha. The structures and absolute configurations of the two new isomers were established to be (2 S,4 R) - and (2 S,4 S)-2,4-dihydroxy-2,7-dimethyl-3,4-dihydronaphthalen-1(2 H)-one ( 1 and 2, respectively) on the basis of spectral analysis, including 2 D NMR, model studies, and CD spectra.
Chen
Yi-Lei
YL
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai, P. R. China.
Tan
Chang-Heng
CH
Tan
Jun-Jie
JJ
Qu
Shi-Jin
SJ
Jiang
Shan-Hao
SH
Zhu
Da-Yuan
DY
D007536:Isomerism; D008961:Models, Structural; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D031828:Pyrola / Q000737:chemistry*; D044024:Tetralones / Q000737:chemistry / Q000302:isolation & purification*
D010936:Plant Extracts; D044024:Tetralones