CRONOS: the cross-reference navigation server.
Cross-mapping of gene and protein identifiers between different databases is a tedious and time-consuming task. To overcome this, we developed CRONOS, a cross-reference server that contains entries from five mammalian organisms presented by major gene and protein information resources. Sequence similarity analysis of the mapped entries shows that the cross-references are highly accurate. In total, up to 18 different identifier types can be used for identification of cross-references. The quality of the mapping could be improved substantially by exclusion of ambiguous gene and protein names which were manually validated. Organism-specific lists of ambiguous terms, which are valuable for a variety of bioinformatics applications like text mining are available for download.


BACKGROUND
CRONOS is freely available to non-commercial users at http://mips.gsf.de/genre/proj/cronos/index.html, web services are available at http://mips.gsf.de/CronosWSService/CronosWS?wsdl.
Waegele
Brigitte
B
Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. brigitte.waegele@helmholtz-muenchen.de
Dunger-Kaltenbach
Irmtraud
I
Fobo
Gisela
G
Montrone
Corinna
C
Mewes
H-Werner
HW
Ruepp
Andreas
A
D000818:Animals; D019295:Computational Biology / Q000295:instrumentation* / Q000379:methods*; D005796:Genes; D006801:Humans; D020407:Internet; D011506:Proteins; D012984:Software
D011506:Proteins