title: Restraint stress up-regulates expression of zinc transporter Zip14 mRNA in mouse liver.
abstract: The zinc concentration in the liver was significantly higher in mice at 12 h after the onset of restraint stress than that without stress. The IL-6 protein level in the serum was transiently elevated at 3 h after the onset of restraint stress, and the IL-6-responsive zinc transporter Zip14 mRNA in the liver was expressed markedly at 6 h. These results suggest that Zip14 plays a major role in the mechanism responsible for accumulation of zinc in the liver under restraint stress.
authors.affiliation: Laboratory of Biosignals and Response, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Ohashi
authors.forename: Tohru
authors.initials: T
authors.lastname: Matsui
authors.forename: Moeko
authors.initials: M
authors.lastname: Chujo
authors.forename: Masaya
authors.initials: M
authors.lastname: Nagao