[Bacterial diarrheas and antibiotics: European recommendations].
The need to limit unnecessary antibiotic treatments and recent studies with unusual antibiotics in pediatrics (fluoroquinolones) or in digestive tract infections (azithromycin) have led to update the treatment of acute gastro-enteritis. In 2007, the European Society for Pediatric Infectious Diseases and the European Society for Gastroenterology Hepatology and Nutrition have issued guidelines. The proven shigellosis as well as the strong suspicion have to be treated promptly with antibiotics, mainly azithromycin. There is no argument to treat moderate salmonella gastroenteritis or carriage. However, the severe cases and those occurring in high risk patient must be treated (ciprofloxacin or ceftriaxone). It is recommended to treat diarrhoea due to Campylobacter jejuni in case of early diagnosis. The presumptive antibiotic treatment should be limited but can not be dismissed, in invasive cases gastro-enteritis, especially in traveller children.
Gendrel
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Université et Faculté de médecine PARIS 5, Hôpital Saint-Vincent de Paul-Cochin, 74 Av Denfert-Rochereau, 75014 Paris, France. dominique.gendrel@svp.aphp.fr
Cohen
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R
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D002169:Campylobacter Infections / Q000188:drug therapy; D016123:Campylobacter jejuni / Q000187:drug effects; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D002939:Ciprofloxacin / Q000627:therapeutic use; D003967:Diarrhea / Q000188:drug therapy / Q000382:microbiology*; D004405:Dysentery, Bacillary / Q000188:drug therapy; D004927:Escherichia coli Infections / Q000188:drug therapy; D005759:Gastroenteritis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D012480:Salmonella Infections / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002443:Ceftriaxone; D017963:Azithromycin