title: Successful sorafenib treatment for metastatic renal cell carcinoma in a case with chronic renal failure.
abstract: Treatment options for patients with end-stage renal disease (ESRD) and metastatic renal cell carcinoma (mRCC) are limited. We report the case of a 69-yr-old male who was treated with sorafenib after failure of immunotherapy. The treatment has resulted in remission with stable disease for 13 mo so far. Sorafenib seems to be a safe treatment option for patients with ESRD and mRCC, but further studies are required.
authors.affiliation: Department of Urology, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Ruppin
authors.forename: Chris
authors.initials: C
authors.lastname: Protzel
authors.forename: Klaus-Jürgen
authors.initials: KJ
authors.lastname: Klebingat
authors.forename: Oliver W
authors.initials: OW
authors.lastname: Hakenberg
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001557:Benzenesulfonates / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000150:complications / Q000188:drug therapy* / Q000556:secondary*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007680:Kidney Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives; D010671:Phenylurea Compounds; D011725:Pyridines / Q000627:therapeutic use*; D000077157:Sorafenib
chemical_list: D000970:Antineoplastic Agents; D001557:Benzenesulfonates; D010671:Phenylurea Compounds; D011725:Pyridines; D009536:Niacinamide; D000077157:Sorafenib