title: [Dynamic contrast-enhanced MR imaging and digital subtraction angiography manifestation of hepatic focal nodular hyperplasia].
abstract: OBJECTIVE
  Focal nodular hyperplasia (FNH) is a rare benign hepatic tumor and its imaging diagnosis remains difficult. This study was to analyze dynamic contrast-enhanced MR imaging and digital subtraction angiography (DSA) manifestation of FNH, and to improve the diagnostic accuracy of FNH.
  
  
  METHODS
  The MRI and DSA imaging data of 30 patients with FNH proved by pathology were reviewed. Conventional contrast-enhanced MRI was completed in 11 patients; dynamic contrast-enhanced MRI was completed in 15 patients. DSA was completed in 10 patients.
  
  
  RESULTS
  On dynamic contrast-enhanced MRI scan, 18 lesions in 15 patients showed obvious enhancement at arterial phase and prolonged enhancement at delayed phase. Central scars were found in 11 lesions, and showed enhancement since portal vein phase till delayed phase. The time-signal intensity curves of the 18 lesions were ascended rapidly at arterial phase, and descended slowly at portal vein phase and delayed phase. On DSA examination, 13 lesions in the ten patients showed dilated feeding arteries, and radiate feeding arterial branches were seen in eight lesions.
  
  
  CONCLUSIONS
  Dynamic contrast-enhanced MRI can fully show abnormal signal of the central scar of FNH. The time-signal intensity curve of FNH ascends rapidly and descends slowly. On DSA imaging, the feeding arteries of FNH spread radially. Dynamic contrast-enhanced MRI and DSA could improve the diagnostic accuracy of FNH.
authors.affiliation: Department of Radiology, The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. gdzhoujx@163.com
authors.forename: Jing-Xing
authors.initials: JX
authors.lastname: Zhou
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Guo-Bin
authors.initials: GB
authors.lastname: Hong
authors.forename: Jiang-Hong
authors.initials: JH
authors.lastname: Luo
authors.forename: Yao-Ting
authors.initials: YT
authors.lastname: Chen
authors.forename: Lin-Feng
authors.initials: LF
authors.lastname: Xu
authors.forename: Bi-Ling
authors.initials: BL
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D015901:Angiography, Digital Subtraction / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement; D008099:Liver / Q000098:blood supply / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D055815:Young Adult