Cross-reactivity of Paracoccidioides brasiliensis, Histoplasma capsulatum, and Cryptococcus species in the commercial Platelia Aspergillus enzyme immunoassay.
Cross-reactivity in the Platelia Aspergillus enzyme immunoassay was evaluated using 120 sera from patients with paracoccidioidomycosis, histoplasmosis, and cryptococcosis. At a cutoff value of 0.5, positivity rates were 50%, 67%, and 50%, respectively. The implications for these findings are discussed.
Xavier
Melissa O
MO
Postgraduation Program in Pulmonary Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Pasqualotto
Alessandro C
AC
Cardoso
Isabel Cristina E
IC
Severo
Luiz Carlos
LC
D000946:Antigens, Fungal / Q000097:blood; D001228:Aspergillosis / Q000175:diagnosis*; D001230:Aspergillus / Q000276:immunology*; D003429:Cross Reactions; D003454:Cryptococcus / Q000276:immunology*; D006658:Histoplasma / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D010228:Paracoccidioides / Q000276:immunology*; D012680:Sensitivity and Specificity
D000946:Antigens, Fungal