title: [Application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors: report of 4 cases].
abstract: OBJECTIVE
  To evaluate the application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors.
  
  
  METHODS
  Four cases with cranio-maxillofacial bone tumors, including one in the frontal bone and three in the mandible, underwent osteoectomy, autologous diseased bone fresh-frozen by nitrogen, re-implantation of the bone and internal fixation by titanium plate to treat the bone tumor and reconstruct the bone defect.
  
  
  RESULTS
  All four cases had one-stage healing 10-14 days after operation. One patient had pathological bone fracture 2 months postoperatively, the other three patients were well-cured without tumor recurrence and gained satisfied cosmetic appearance during 6 months to 3 years of follow-up. The X-ray films showed that the frozen bone was substituted by new bone formation.
  
  
  CONCLUSIONS
  Autologous bone fresh-frozen and re-implantation is a feasible method in cranio-maxillofacial bone tumor treatment, especially for young patients. It make possible to do radical surgery and reconstruct the bone defect simultaneously, and is thus worthy of clinical application.
authors.affiliation: Department of Stomatology, Taizhou Shili Hospital, Taizhou 318000, Zhejiang Province, China.
authors.forename: Shun-Yue
authors.initials: SY
authors.lastname: Chen
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Liu
authors.forename: Yu
authors.initials: Y
authors.lastname: Lu
authors.forename: Yong-Jie
authors.initials: YJ
authors.lastname: Hu
mesh_terms: D001860:Bone Plates; D016025:Bone Transplantation; D015925:Cryopreservation; D005153:Facial Neoplasms / Q000601:surgery*; D006801:Humans; D008334:Mandible; D008339:Mandibular Neoplasms / Q000601:surgery*; D019651:Plastic Surgery Procedures