[Studies on lignan constituents of Clematis parviloba].
OBJECTIVE
To study the chemical constituents of the stems of Clematis parviloba.


METHODS
The compounds were isolated and purified by repeated column chromatography with silica gel, Sephadex LH-20 and HPLC. Their structures were identified by spectroscopic data together with physical and chemical property.


RESULTS
Ten compounds have been isolated from the stems of C. parviloba, and identified as: (+) pinoresionol (1), (+) pinoresionol-4'-O-p-D-glucopyranoside (2), ( +) pinoresionol4, 4'-O-bis-beta-D-glucopyranoside (3), (-) syringaresinol (4), (+) syringaresinol-4'-O-beta-D-glucopyranoside (5), (-)episyringaresinol (6), (+) medioresinol-4'-O-beta-D-glucopyranoside (7), (+) lariciresinol-4-O-beta-D-glucopyranoside (8), (+) lariciresinol-4'-O-beta-D-glucopyranoside (9), (+) lariciresinol-4, 4'-O-bis-beta-D-glucopyranoside (10), respectively.


CONCLUSIONS
Compounds 6, 7 were isolated from this genus for the first time, and the other ones were isolated from this plant for the first time.
Yan
Li-hua
LH
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
Xu
Li-zhen
LZ
Lin
Jia
J
Zou
Zhong-mei
ZM
Zhao
Bao-hua
BH
Yang
Shi-lin
SL
D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D039324:Clematis / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
D004365:Drugs, Chinese Herbal; D005663:Furans; D005960:Glucosides; D017705:Lignans; C042192:syringaresinol; C103298:pinoresinol