title: Therapeutic control of the circulation.
abstract: By regarding the circulation from the perspective of the venous return, continuous therapeutic control of the mean arterial blood pressure, cardiac output and tissue oxygen flow can be seen to be the consequence of a series of equations based on conventionally measured variables. This approach permits a graphical solution to circulation guidance, open or closed loop control and goal directed therapy of broad general applicability.
authors.affiliation: Applied Physiology Pty Ltd, Sydney, Australia. geoffrey.parkin@applied-physiology.com
authors.forename: William Geoffrey
authors.initials: WG
authors.lastname: Parkin
authors.forename: Mark Stephen
authors.initials: MS
authors.lastname: Leaning
mesh_terms: D001775:Blood Circulation / Q000187:drug effects / Q000502:physiology*; D002302:Cardiac Output / Q000187:drug effects / Q000502:physiology*; D002316:Cardiotonic Agents / Q000008:administration & dosage*; D003198:Computer Simulation; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D005246:Feedback / Q000187:drug effects / Q000502:physiology; D006321:Heart / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D014655:Vascular Resistance / Q000502:physiology*
chemical_list: D002316:Cardiotonic Agents