title: [Combination and transformation of toxin and blood stasis in etiopathogenesis of thrombotic cerebro-cardiovascular diseases].
abstract: According to the basic theory of traditional Chinese medicine (TCM), the pathogenetic factors such as platelet activation, adhesion, congregation and thrombosis fall into the category of blood stasis, while the pathological changes such as tissue necrosis, oxidative stress injury and inflammation, etc, are far beyond the etiological category of blood stasis. The toxin or the combination and transformation of toxin and blood stasis of TCM are involved in the pathogenesis of thrombotic cerebro-cardiovascular diseases. It is significant to recognize and stress the combination and transformation of toxin and stasis in pathogenicity so as to enrich TCM etiology and improve TCM clinical efficacy in the treatment of cerebro-cardiovascular and thrombotic diseases.
authors.affiliation: Cardiovascular Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China. shidz666@sohu.com
authors.forename: Da-zhuo
authors.initials: DZ
authors.lastname: Shi
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
authors.forename: Hui-jun
authors.initials: HJ
authors.lastname: Yin
authors.forename: Jing-chun
authors.initials: JC
authors.lastname: Zhang
authors.forename: Ke-ji
authors.initials: KJ
authors.lastname: Chen
mesh_terms: D003328:Coronary Thrombosis / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000473:pathology; D008516:Medicine, Chinese Traditional / Q000379:methods*; D013927:Thrombosis / Q000175:diagnosis / Q000473:pathology*