Investigation of C/EBPalpha function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML).
Niebuhr
B
B
Iwanski
G B
GB
Schwieger
M
M
Roscher
S
S
Stocking
C
C
Cammenga
J
J
D000818:Animals; D022762:CCAAT-Enhancer-Binding Proteins / Q000037:antagonists & inhibitors / Q000502:physiology*; D002454:Cell Differentiation; D003114:Colony-Forming Units Assay; D019281:Dimerization; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D009154:Mutation / Q000235:genetics*; D022423:Myeloid Cells / Q000378:metabolism; D038042:Myelopoiesis / Q000502:physiology*; D034741:RNA, Small Interfering / Q000494:pharmacology; D013234:Stem Cells / Q000378:metabolism
D022762:CCAAT-Enhancer-Binding Proteins; C515848:CEBPA protein, human; C530718:CEBPA protein, mouse; D034741:RNA, Small Interfering