[Antibiotic resistance of bacterial strains in paediatric infections: there are resistance and resistance!].
Isolation of a bacterial strain at the infectious site and determination of the susceptibility profile may help to guide appropriate antibiotic treatment. However technical difficulties justify interpretative reading to recognize interfering resistance mechanisms from resistance phenotypes. The aim of this article is to give some examples showing interpretative reading of routine sensitivity test data.
Bingen
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Service de Microbiologie, Hôpital Robert Debré 48, bld Sérurier, 75019 Paris, France. edouard.bingen@rdb.aphp.fr
D000658:Amoxicillin / Q000494:pharmacology; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000494:pharmacology; D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology; D017963:Azithromycin / Q000494:pharmacology; D001419:Bacteria / Q000145:classification / Q000187:drug effects*; D018550:Cephalosporin Resistance; D002512:Cephalothin / Q000494:pharmacology; D002648:Child; D002939:Ciprofloxacin / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial; D004357:Drug Synergism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D019384:Nucleic Acid Synthesis Inhibitors / Q000494:pharmacology; D012764:Shigella sonnei / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D001618:beta-Lactamases / Q000502:physiology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D004791:Enzyme Inhibitors; D019384:Nucleic Acid Synthesis Inhibitors; D009268:Nalidixic Acid; D002981:Clindamycin; D002939:Ciprofloxacin; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin; D017963:Azithromycin; D001618:beta-Lactamases; D002512:Cephalothin