Lateralization effects on the cardiac modulation of acoustic startle eye blink.
Cardiac modulation of startle eye blink has been introduced as a methodology to reflect baro-afferent signal transmission. Recent studies showed that affective startle modulation is specific to left-ear presentation that may be due to hemispheric specificity in processing emotional-relevant stimuli, similar to the processing of visceral- and baro-afferent stimuli. To explore whether cardiac modulation of startle eye blink is lateralized as well, 37 healthy volunteers received 160 unilateral acoustic startle probes of 105 dB(A) intensity presented to both ears, one at a time. They were elicited 0, 100, 230, and 530 ms after the R-wave of the cardiac cycle. Startle response magnitude was significantly diminished at a latency of 230 ms, which may be due to the baro-afferent neural feedback at this temporal location, but only for left-ear presentation. This lateralization effect in the cardiac modulation of startle eye blink may reflect the previously described advantages of right-hemispheric brain structures in relaying viscero- and baro-afferent signal transmission.
Schulz
André
A
Division of Clinical Physiology, Institute of Psychobiology, University of Trier, Johanniterufer 15, D-54290 Trier, Germany. andre.schulz@uni-trier.de
Lass-Hennemann
Johanna
J
Richter
Steffen
S
Römer
Sonja
S
Blumenthal
Terry D
TD
Schächinger
Hartmut
H
D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D000704:Analysis of Variance; D001767:Blinking / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods; D004576:Electromyography; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006321:Heart / Q000502:physiology*; D006801:Humans; D008297:Male; D011930:Reaction Time / Q000502:physiology; D013216:Reflex, Startle / Q000502:physiology*; D013997:Time Factors; D055815:Young Adult