Antioxidant capacity and antimutagenic activity of natural oleoresin from greenhouse grown tomatoes (Lycopersicon esculentum).
Natural oleoresins rich in lycopene were obtained from two varieties of tomato (Zedona and Gironda) and their nutraceutical potential (antioxidant and antimutagenic capacity) was evaluated. Both oleoresins had a high content of lycopene, 58.33+/-1.67 mg/g (Zedona) and 63.97+/-0.80 mg/g (Gironda). The antioxidant activity (AA) of the oleoresins by beta-carotene method were 56.4-74.5% (Zedona) and 51-72.8% (Gironda), while when using the free radical stable 2,2-diphenyl-picryl-hydrazyl (DPPH) method, the antiradical activity (ARA) was determined to be 18.2-32.7% (Zedona) and 16.6-26.7% (Gironda) for the concentrations tested that of 200-400 microM equivalents of lycopene. The antimutagenic activity of the oleoresins was tested against aflatoxin B1 (AFB1) using the microsuspension assay, both varieties had a very high antimutagenic potential against AFB1 (60-66%).These results suggest the NCRT can be taken advantage to obtaining rich oleoresin in lycopene with a nutraceutical value.
Rodríguez-Muñoz
Eustolia
E
Centro de Estudios Académicos sobre Contaminación Ambiental, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Qro, 76010, Mexico.
Herrera-Ruiz
Gilberto
G
Pedraza-Aboytes
Gustavo
G
Loarca-Piña
Guadalupe
G
D016604:Aflatoxin B1 / Q000633:toxicity; D016587:Antimutagenic Agents / Q000032:analysis / Q000378:metabolism*; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism*; D002338:Carotenoids / Q000032:analysis / Q000378:metabolism*; D016166:Free Radical Scavengers; D006801:Humans; D000077276:Lycopene; D018551:Solanum lycopersicum / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis / Q000378:metabolism*
D016587:Antimutagenic Agents; D000975:Antioxidants; D016166:Free Radical Scavengers; D010936:Plant Extracts; C018620:oleoresins; D002338:Carotenoids; D016604:Aflatoxin B1; D000077276:Lycopene