title: Twelve pregnane glycosides from Cynanchum atratum.
abstract: Eleven new 14,15-seco-pregnane-type steroidal glycosides, cynanosides P1-P5, Q1-Q3, R1-R3, and a novel 12,13-seco-14,18-nor-pregnane-type steroidal glycoside, cynanoside S, were isolated from the roots of Cynanchum atratum, together with four known compounds, atratoside C, sublanceoside E3, chekiangensoside C and cynatroside B. Their structures were determined on the basis of spectroscopic analysis and chemical evidence.
authors.affiliation: Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
authors.forename: Hong
authors.initials: H
authors.lastname: Bai
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Asada
authors.forename: Tadaaki
authors.initials: T
authors.lastname: Satou
authors.forename: Yuanshu
authors.initials: Y
authors.lastname: Wang
authors.forename: Kazuo
authors.initials: K
authors.lastname: Koike
mesh_terms: D002942:Circular Dichroism; D031105:Cynanchum / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D011278:Pregnanes