Sensors, transducers, and effectors that regulate cell size and shape.
Cell volume and shape are stringently regulated. This homeostasis requires the cells to sense their size and shape and to convey this information to effectors that will counteract deformations induced by osmotic or mechanical challenges. The sensors, transducers, and effectors of volume change are the subject of this review.
Koivusalo
Mirkka
M
Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.
Kapus
Andras
A
Grinstein
Sergio
S
D000818:Animals; D048429:Cell Size; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D009995:Osmosis; D015398:Signal Transduction / Q000502:physiology*