title: Determinants of unplanned antiretroviral treatment interruptions among people living with HIV in Yaoundé, Cameroon (EVAL survey, ANRS 12-116).
abstract: OBJECTIVE
  To identify correlates of self-reported antiretroviral therapies (ART) interruptions among people living with HIV and AIDS (PLWHA) in Cameroon.
  
  
  METHODS
  Analyses were based on data collected in the national survey EVAL (ANRS 12-116) among 533 ART-treated PLWHA in Yaoundé, the capital city of Cameroon, and its neighbourhood. Logistic regression models were used to identify factors associated with self-reported ART interruptions longer than two consecutive days during the previous 4 weeks.
  
  
  RESULTS
  ART interruptions were reported by 68 patients (12.8%). After adjustment for gender, education and household income, characteristics independently associated with interruptions were pharmacy stock shortages [OR (95%CI):3.25 (1.78-5.90)], binge drinking [2.87 (1.39-5.91)] and the number of self-reported slimming symptoms [1.23 (1.02-1.48)].
  
  
  CONCLUSIONS
  In poor-resource settings where access to second and third-line regimens is still limited, food supply programs and interventions to minimise ART shortage may reduce the risk of ART interruptions.
authors.affiliation: INSERM U912/ORS PACA, 23 rue Stanislas Torrents, 13006 Marseille, France. fabienne.marcellin@inserm.fr
authors.forename: Fabienne
authors.initials: F
authors.lastname: Marcellin
authors.forename: Sylvie
authors.initials: S
authors.lastname: Boyer
authors.forename: Camelia
authors.initials: C
authors.lastname: Protopopescu
authors.forename: Aissata
authors.initials: A
authors.lastname: Dia
authors.forename: Pierre
authors.initials: P
authors.lastname: Ongolo-Zogo
authors.forename: Sinata
authors.initials: S
authors.lastname: Koulla-Shiro
authors.forename: Séverin-Cécile
authors.initials: SC
authors.lastname: Abega
authors.forename: Claude
authors.initials: C
authors.lastname: Abé
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Moatti
authors.forename: Bruno
authors.initials: B
authors.lastname: Spire
authors.forename: Maria Patrizia
authors.initials: MP
authors.lastname: Carrieri
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D000328:Adult; D000428:Alcohol Drinking; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000600:supply & distribution / Q000627:therapeutic use; D002163:Cameroon; D003430:Cross-Sectional Studies; D004334:Drug Administration Schedule; D005260:Female; D005523:Food Supply; D015658:HIV Infections / Q000188:drug therapy*; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008297:Male; D010349:Patient Compliance / Q000706:statistics & numerical data*
chemical_list: D019380:Anti-HIV Agents