title: Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts.
abstract: Perdeuterated poly(styrene) is introduced as an almost artefact-free and arbitrarily scalable alignment medium for measuring residual dipolar couplings and other anisotropic NMR parameters; the spectral quality achievable in this new medium is demonstrated for HSQC spectra leading to the conformational analysis of staurosporine and homonuclear TOCSY-type experiments.
authors.affiliation: Center of Integrated Protein Science at the Department of Chemistry, Technische Universität München, Lichtenbergstr. 4, 85747, Garching, Germany.
authors.forename: Grit
authors.initials: G
authors.lastname: Kummerlöwe
authors.forename: Sebastian
authors.initials: S
authors.lastname: Knör
authors.forename: Andreas O
authors.initials: AO
authors.lastname: Frank
authors.forename: Thomas
authors.initials: T
authors.lastname: Paululat
authors.forename: Horst
authors.initials: H
authors.lastname: Kessler
authors.forename: Burkhard
authors.initials: B
authors.lastname: Luy
mesh_terms: D016880:Anisotropy; D016477:Artifacts; D003903:Deuterium / Q000737:chemistry; D005782:Gels / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011137:Polystyrenes / Q000737:chemistry*; D019311:Staurosporine / Q000737:chemistry
chemical_list: D005782:Gels; D011137:Polystyrenes; D003903:Deuterium; D019311:Staurosporine