title: Hirschsprung disease.
abstract: Hirschsprung disease is a relatively common condition managed by pediatric surgeons. Significant advances have been made in understanding its etiologies in the last decade, especially with the explosion of molecular genetic techniques and early diagnosis. The surgical management has progressed from a two- or three-stage procedure to a primary operation. More recently, definitive surgery for Hirschsprung disease through minimally invasive techniques has gained popularity. In neonates, the advancement of treatment strategies for Hirschsprung disease continues with reduced patient morbidity and improved outcomes.
authors.affiliation: Division of Pediatric Surgery, Department of General Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
authors.forename: Ramanath N
authors.initials: RN
authors.lastname: Haricharan
authors.forename: Keith E
authors.initials: KE
authors.lastname: Georgeson
mesh_terms: D000714:Anastomosis, Surgical; D003937:Diagnosis, Differential; D013505:Digestive System Surgical Procedures / Q000009:adverse effects / Q000379:methods; D006627:Hirschsprung Disease / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn