title: Pol V transcribes to silence.
abstract: In most cases, the functions of long noncoding RNAs remain uncertain. Working in the model plant Arabidopsis, Wierzbicki et al. (2008) provide evidence that transcription of intergenic noncoding regions by RNA polymerase V promotes heterochromatin formation and silencing of nearby genes.
authors.affiliation: Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna, Austria.
authors.forename: Lucia
authors.initials: L
authors.lastname: Daxinger
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kanno
authors.forename: Marjori
authors.initials: M
authors.lastname: Matzke
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D044127:Epigenesis, Genetic; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D017343:Genes, Plant; D006570:Heterochromatin / Q000378:metabolism; D008954:Models, Biological; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D034741:RNA, Small Interfering / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D006570:Heterochromatin; D034741:RNA, Small Interfering; D012321:DNA-Directed RNA Polymerases