title: [Obesity in children and adolescents and their parents. Correlation of standardized body mass index between patients, their parents and siblings from the multicentre APS data].
abstract: BACKGROUND
  Obesity in children and adolescents is moving into the focus of public interest. Genetic as well as environmental factors are important in the etiology of obesity. The aim of this multicentre study was to correlate the weight of overweight or obese children and adolescents with that of their parents and siblings.
  
  
  METHODS
  Anthropometric and other data - comorbidities, various influencing factors and treatment - were collected from the adiposity data acquisition system for prospective surveillance (APS). Currently 125 medical centers and pediatric care clinics in Germany, Austria and Switzerland use the APS documentation. Until February 2008 data on a total of 37,062 children and adolescents had been collected.
  
  
  RESULTS
  Data to calculate the Body Mass Index (BMI) were obtained from both parents of 11,074 (29,9%) children and adolescents. The mean BMI Standard Deviation Score (SDS) of these children and adolescents was 2.46. Their mean age was 11.9 years; 46% were males. The mean BMI-SDS of these children and adolescents correlated significantly with the BMI-SDS of both the mother (r=0.29 [Spearman's rank correlation coefficient]) and the father (r=018, both p<0.0001). The correlation with the father's BMI was closer in adolescents (15-20 years, r=0.20) than in young children (<10 years: r=0.12). The correlation with the mother's BMI was independent of age. A multivariate model including the BMI of the parents as well as age and sex of the children and adolescents explained 10.0% of the variance. Significant influencing factors were BMI of the mother, sex and the relationship between BMI of mother, age and sex. Data for the BMI of siblings were available of 3,933 (10.6 %) children and adolescents. The correlation of the BMI of the children and adolescents with that of their siblings was +0.17 (p<0.0001). This correlation was highest in adolescence (<10 years.: r=0.17, 15-20 years.: r=0.24, both p<0.0001).
  
  
  CONCLUSIONS
  The patient's weight correlated more strongly with the mother's than the father's weight or that of the siblings.
authors.affiliation: Pädiatrie 2, Universitäts-Kinderklinik Göttingen, Göttingen. markus.roebl@med.uni-goettingen.de
authors.forename: M
authors.initials: M
authors.lastname: Röbl
authors.forename: I
authors.initials: I
authors.lastname: Knerr
authors.forename: K M
authors.initials: KM
authors.lastname: Keller
authors.forename: R
authors.initials: R
authors.lastname: Jaeschke
authors.forename: U
authors.initials: U
authors.lastname: Hoffmeister
authors.forename: T
authors.initials: T
authors.lastname: Reinehr
authors.forename: R W
authors.initials: RW
authors.lastname: Holl
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria / Q000453:epidemiology; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000235:genetics; D050177:Overweight / Q000453:epidemiology / Q000235:genetics; D010290:Parents; D012307:Risk Factors; D012737:Sex Factors; D035781:Siblings; D013557:Switzerland / Q000453:epidemiology; D055815:Young Adult