title: [Intranasal administration of immunoglobulins--perspectives for use in medical practice].
abstract: Effectiveness of topical use of immunoglobulines in respiratory infections along with preparations for parenteral use is discussed. Immunoglobuline preparations for intranasal use (drops, spays, aerosols) should take place among preparations intended for prevention and treatment of influenza, parainfluenza, respiratory syncitial virus infection and others. Potential to intranasal use of complex immunoglobulin preparation containing polymeric and monomeric antibodies of different isotypes is also discussed.
authors.forename: L I
authors.initials: LI
authors.lastname: Novikova
authors.forename: V A
authors.initials: VA
authors.lastname: Aleshkin
authors.forename: I V
authors.initials: IV
authors.lastname: Borisova
authors.forename: M M
authors.initials: MM
authors.lastname: Zueva
mesh_terms: D000281:Administration, Intranasal; D000336:Aerosols; D006801:Humans; D007070:Immunoglobulin A / Q000008:administration & dosage; D007136:Immunoglobulins / Q000008:administration & dosage*; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000517:prevention & control / Q000821:virology
chemical_list: D000336:Aerosols; D007070:Immunoglobulin A; D007136:Immunoglobulins