title: Enantioselective oxidation of racemic lactic acid to D-lactic acid and pyruvic acid by Pseudomonas stutzeri SDM.
abstract: D-lactic acid and pyruvic acid are two important building block intermediates. Production of D-lactic acid and pyruvic acid from racemic lactic acid by biotransformation is economically interesting. Biocatalyst prepared from 9 g dry cell wt l(-1) of Pseudomonas stutzeri SDM could catalyze 45.00 g l(-1)DL-lactic acid into 25.23 g l(-1)D-lactic acid and 19.70 g l(-1) pyruvic acid in 10h. Using a simple ion exchange process, D-lactic acid and pyruvic acid were effectively separated from the biotransformation system. Co-production of d-lactic acid and pyruvic acid by enantioselective oxidation of racemic lactic acid is technically feasible.
authors.affiliation: State Key Laboratory of Microbial Technology, Shandong University, Shandananlu 27, Jinan 250100, People's Republic of China.
authors.forename: Chao
authors.initials: C
authors.lastname: Gao
authors.forename: Jianhua
authors.initials: J
authors.lastname: Qiu
authors.forename: Jingchen
authors.initials: J
authors.lastname: Li
authors.forename: Cuiqing
authors.initials: C
authors.lastname: Ma
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Tang
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
mesh_terms: D001709:Biotechnology / Q000379:methods*; D001711:Biotransformation; D002384:Catalysis; D019344:Lactic Acid / Q000378:metabolism*; D010084:Oxidation-Reduction; D044223:Pseudomonas stutzeri / Q000378:metabolism*; D019289:Pyruvic Acid / Q000378:metabolism*
chemical_list: D019344:Lactic Acid; D019289:Pyruvic Acid