[Effect of Mailuoning injectable powder on experimental vascular occlusion angeitides in rats].
OBJECTIVE
To investigate the effect of Mailuoning injectable powder on experimental vascular occlusion angeitides in rats.


METHODS
Rats were injected laurostearic acid into arteria cruralis to induce the model of experimental vascular occlusion angeitides, then we observed the changes of objective sign of rats, and analysed throm ranking through pathological section under electro-microscope.


RESULTS
Mailuoning injectable powder could decrease the quantity of throm in blood vessel, and improve hemorrheoiogy.


CONCLUSIONS
The results show that Mailuoning injectable powder has obvious therapeutical effect on experimental vascular occlusion angeitides in rats, and its mechanism may be related to the anti-throm in blood vessel and improving hemorrheology.
Miao
Zhi-Ru
ZR
Department of Pharmacy, First People's Hospital of Xiaoshan, Hangzhou 311200, China.
Huang
Xia-Qin
XQ
Cheng
Xiao-Li
XL
Chen
Jin-Wen
JW
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D004195:Disease Models, Animal; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D018056:Hemorheology; D007275:Injections, Intravenous; D007850:Lauric Acids; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013919:Thromboangiitis Obliterans / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D007850:Lauric Acids