title: The spontaneous loss of coherence catastrophe in Fourier transform ion cyclotron resonance mass spectrometry.
abstract: The spontaneous loss of coherence catastrophe (SLCC) is a frequently observed, yet poorly studied, space-charge related effect in Fourier-transform ion cyclotron resonance mass spectrometry (FTICR-MS). This manuscript presents an application of the filter diagonalization method (FDM) in the analysis of this phenomenon. The temporal frequency behavior reproduced by frequency shift analysis using the FDM shows the complex nature of the SLCC, which can be explained by a combination of factors occurring concurrently, governed by electrostatics and ion packet trajectories inside the ICR cell.
authors.affiliation: Cardiovascular Proteomics Center, Boston University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Aizikov
authors.forename: Raman
authors.initials: R
authors.lastname: Mathur
authors.forename: Peter B
authors.initials: PB
authors.lastname: O'Connor
mesh_terms: D003198:Computer Simulation; D017357:Cyclotrons; D005583:Fourier Analysis; D013058:Mass Spectrometry / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D017550:Spectroscopy, Fourier Transform Infrared; D055672:Static Electricity