title: Adequate hypnosis at very low isoflurane concentration during craniotomy monitored by electroencephalography.
abstract: We report a patient with Parkinson's disease undergoing craniotomy for a brain tumor, who had clinically adequate hypnosis at a very low concentration of isoflurane. While the raw EEG showed low-voltage slow electrical activity, the EEG analyzer of the monitor displayed high burst suppression ratios. The role of intracranial pathology and drug therapy as possible causes of the low anesthetic requirement for adequate hypnosis are discussed. This report also draws attention to the possibility of erroneous analysis of burst suppression by EEG modules.
authors.affiliation: Department of Neuroanaesthesia, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, 560 029, India.
authors.forename: Amruthalingam
authors.initials: A
authors.lastname: Jaganath
authors.forename: Mukkanna
authors.initials: M
authors.lastname: Ramesh
authors.forename: Muthuchellappan
authors.initials: M
authors.lastname: Radhakrishnan
authors.forename: Ganne S
authors.initials: GS
authors.lastname: Umamaheswara Rao
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000601:surgery; D003399:Craniotomy; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage; D016343:Monitoring, Intraoperative; D010300:Parkinson Disease / Q000150:complications
chemical_list: D018685:Anesthetics, Inhalation; D007530:Isoflurane