title: Protein quality control: on IPODs and other JUNQ.
abstract: The accumulation of misfolded cytosolic or aggregation-prone proteins leads to cellular stress. To protect the cell, damaged or aggregated proteins are actively sequestered in two newly discovered quality control compartments, JUNQ and IPOD, which are highly conserved in evolution.
authors.affiliation: Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Str.10, 13125 Berlin, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Bagola
authors.forename: Thomas
authors.initials: T
authors.lastname: Sommer
mesh_terms: D002451:Cell Compartmentation; D017510:Protein Folding; D011506:Proteins / Q000378:metabolism*; D013312:Stress, Physiological; D054875:Ubiquitination
chemical_list: D011506:Proteins