title: Determination of chemical warfare agents: Gas Chromatographic analysis of chlorovinylarsines (Lewisite) and their metabolites by derivatization with thiols (2nd communication).
abstract: Chlorovinylannes (Lewisites) were produced and handled during WW I and WW II as chemical warfare agents. Residues of these cwa and their metabolites are still present today and continue to contaminate soil and water. A gas Chromatographic method for the detection and determination of chlorovinylarsines (Lewisites) and their metabolites is shown. Lewisite II and Lewisite III, but not Lewisite I and the metabolites of Lewisite I and Lewisite II can be detected and determined using GC/ECD. After derivatization with thiols, the sum of Lewisite I or Lewisite II and their metabolites are detected. With the proper selection of the thiol, matrix interferences can be eliminated because of the different retention times of the derivatives.
authors.affiliation: Büro für Altlastenerkundung und Umweltforschung, Stadtwaldstr. 45a, D-35037, Marburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Haas