title: Dietary intake and serum bone related chemistry and their correlations in postmenopausal Iranian women.
abstract: OBJECTIVE
  To determine dietary intake and bone related chemistry of osteoporosis and their correlations in postmenopausal Iranian women.
  
  
  METHODS
  A cross-sectional study was carried out on 58 healthy Iranian, postmenopausal women from January 2005 until August 2006, at Sina Hospital, Tabriz, Iran. Serum calcium, phosphorus, magnesium, and alkaline phosphatase were measured using auto analyzer and parathyroid hormone (PTH) by immune radio metric assay. Dietary intake was assessed by 3-day dietary record. Bone mineral density (BMD) was assessed by dual-energy x-ray absorptiometry (DXA) at the lumbar spine and left femur. Comparison between means of the groups was carried out using one-way analysis of variance test. To examine the correlation between dietary factors and bone related chemistry markers, multiple and linear regression was used.
  
  
  RESULTS
  According to the results of lumbar spine BMD, women (n=58) were classified into 3 groups: normal (n=18), osteopenia (n=22), and osteoporosis (n=18). The mean serum calcium, phosphorus, magnesium, and alkaline phosphatase in 3 groups were in the normal range. Serum PTH in the osteoporosis group was higher than other groups. The mean dietary calcium intake in the osteoporosis groups was significantly lower than the normal group (p=0.01). The results of analyzing by linear regression, showed a significant correlation between calcium intake and PTH (r = -0.61, p = 0.0001, B = -0.032).
  
  
  CONCLUSIONS
  These findings suggest that postmenopausal women need to be educated regarding osteoporosis and the related preventive measures, such as the effect of nutrients on bone health, and the adequate intake of dairy products and calcium rich-foods.
authors.affiliation: Nutritional Research Center, School of Health & Nutrition, Tabriz University of Medical Sciences, Golgasht Avenue, Attare Neyshabury Street, Tabriz, Iran. nazila_farrin@yahoo.com
authors.forename: Nazila
authors.initials: N
authors.lastname: Farrin
authors.forename: Ali R
authors.initials: AR
authors.lastname: Ostadrahimi
authors.forename: Soltan A
authors.initials: SA
authors.lastname: Mahboob
authors.forename: Sousan
authors.initials: S
authors.lastname: Kolahi
authors.forename: Mostafa
authors.initials: M
authors.lastname: Ghavami
mesh_terms: D015502:Absorptiometry, Photon; D015519:Bone Density; D002136:Calcium, Dietary / Q000008:administration & dosage; D004032:Diet; D005260:Female; D006801:Humans; D007492:Iran; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*; D017698:Postmenopause
chemical_list: D002136:Calcium, Dietary; D010281:Parathyroid Hormone