title: Results of liver transplantation at the Cuban Center for Medical and Surgical Research.
abstract: From July 4, 1999, when a liver transplantation program was started in Cuba, to December 30, 2007, we performed 125 procedures in 115 patients. The most frequent reasons for transplantation were cirrhosis caused by hepatitis C virus (29%) and alcoholic cirrhosis (17.2%). Two patients received simultaneous liver-kidney transplants. Sixty-seven patients were males, and the patient ages ranged from 12 to 74 years. The average surgical time was 6 hours, and cold ischemia time was 4 to 14 hours. The average blood consumption was 1630 mL; 2900 mL of plasma and 8 units of platelets were used in 7 cases. Immunosuppression was mainly cyclosporine, mycophenolate mofetil, and prednisone. Acute cellular rejections were treated in almost all cases with 3 doses of methylprednisolone. The most frequent complications were biliary (15%), hepatic arterial thrombosis (6%), postsurgical bleeding (8%), acute cellular rejection (20%), and ductopenic rejection (2%). The overall 1-year survival was 74.7%.
authors.affiliation: Medical-Surgical Research Center, Havana City, Cuba.
authors.forename: L
authors.initials: L
authors.lastname: González-Rapado
authors.forename: A
authors.initials: A
authors.lastname: Abdo
authors.forename: H
authors.initials: H
authors.lastname: Hernández
authors.forename: M
authors.initials: M
authors.lastname: Cepero
authors.forename: M
authors.initials: M
authors.lastname: Samada
authors.forename: L
authors.initials: L
authors.lastname: Ramos
authors.forename: R
authors.initials: R
authors.lastname: Ysla
authors.forename: F
authors.initials: F
authors.lastname: Gómez
authors.forename: D
authors.initials: D
authors.lastname: Delgado
authors.forename: K
authors.initials: K
authors.lastname: Melián
authors.forename: C
authors.initials: C
authors.lastname: González
authors.forename: J
authors.initials: J
authors.lastname: Pérez
authors.forename: A
authors.initials: A
authors.lastname: Bernardos
mesh_terms: D003462:Cuba; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008107:Liver Diseases / Q000145:classification / Q000601:surgery; D016031:Liver Transplantation / Q000276:immunology / Q000379:methods / Q000706:statistics & numerical data*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies
chemical_list: D007166:Immunosuppressive Agents