title: Lemierre's syndrome.
abstract: Lemierre's syndrome is a rare disease that results in an oropharyngeal infection, which precipitates an internal jugular vein thrombosis and metastatic infection. Fusobacterium necrophorum is an anaerobic Gram-negative bacillus and has been identified as the causative agent. We describe the case of a young girl whose presentation and diagnosis were confounded by a history of valvular heart disease. Infection of heart valves can produce many of the signs and symptoms associated with Lemierre's syndrome. We describe the diagnosis, investigation and optimal management of this rare disorder.
authors.affiliation: St Vincent's University Hospital, Elm Park, Dublin 4, Ireland. daviodwyer@gmail.com
authors.forename: D N
authors.initials: DN
authors.lastname: O'Dwyer
authors.forename: S
authors.initials: S
authors.lastname: Ryan
authors.forename: T
authors.initials: T
authors.lastname: O'Keefe
authors.forename: J
authors.initials: J
authors.lastname: Lyons
authors.forename: L
authors.initials: L
authors.lastname: Lavelle
authors.forename: E
authors.initials: E
authors.lastname: McKone
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004696:Endocarditis / Q000175:diagnosis; D005260:Female; D006801:Humans; D057831:Lemierre Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D011655:Pulmonary Embolism / Q000175:diagnosis
chemical_list: D000900:Anti-Bacterial Agents