The effect of iron and zinc dietary restriction of pregnant rats on physical growth of litters.
Evidence suggests that micronutrient deficiencies may be associated with problems in early growth. Iron (Fe) and Zinc (Zn) deficiency (D) are prevalent during gestation in low-income countries. For pregnant dams, adequate amount of these micronutrients are needed in the diet to ensure the capacity for increased physical growth. In this study, the role of Fe and Zn dietary restriction of pregnant rats on physical growth of litters was investigated. Pregnant rats after to mating were divided to three groups. Control group fed a standard diet and a FeD group fed a diet deficient in Fe and a ZnD group fed a diet deficient in Zn. All the diets were exposed during the last third of pregnancy. The results showed serum Fe and Zn concentration after to exert dietary compared to before to exert dietary in FeD and ZnD groups was significant. There was a significant difference in the physical growth indexes (body weight, body length, tail length, and head length) between FeD and ZnD groups compared to the Control group, but a significant difference in head width and brain weight between FeD and ZnD groups compared to the Control group was not seen. The results of this study suggest that adequate Fe and Zn affect the physical growth of litters.
Shahbazi
M
M
University of Tehran, Iran. shahbazimehdi@yahoo.com
Naghdi
N
N
Tahmasebi
S
S
Sheikh
M
M
Namvar Asl
N
N
Kazemnejad
A
A
D000818:Animals; D000831:Animals, Newborn; D001724:Birth Weight / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D001921:Brain / Q000033:anatomy & histology; D004032:Diet; D005260:Female; D006257:Head / Q000033:anatomy & histology; D007501:Iron / Q000008:administration & dosage* / Q000097:blood; D000090463:Iron Deficiencies; D008297:Male; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar; D013623:Tail / Q000033:anatomy & histology; D015032:Zinc / Q000008:administration & dosage* / Q000097:blood / Q000172:deficiency
D007501:Iron; D015032:Zinc