title: Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center.
abstract: The Lung Cancer SPORE at University Texas MDAnderson Cancer Center and Southwestern Medical School requires the integration of heterogeneous multi-institutional sources comprising both molecular and clinical data. In this report we describe a novel method for converging domain specific experimental ontologies that relies on propagating permissions in Resource Description Framework triplets rather than the single access point of conventional relational databases. We address this challenge by combining semantic web data reposition with code distribution.
authors.affiliation: Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Helena F
authors.initials: HF
authors.lastname: Deus
authors.forename: Romesh
authors.initials: R
authors.lastname: Stanislaus
authors.forename: Carmen
authors.initials: C
authors.lastname: Behrens
authors.forename: Ignacio I
authors.initials: II
authors.lastname: Wistuba
authors.forename: John D
authors.initials: JD
authors.lastname: Minna
authors.forename: Harold R
authors.initials: HR
authors.lastname: Garner
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Swisher
authors.forename: Jack A
authors.initials: JA
authors.lastname: Roth
authors.forename: Arlene M
authors.initials: AM
authors.lastname: Correa
authors.forename: Bradley
authors.initials: B
authors.lastname: Broom
authors.forename: Kevin
authors.initials: K
authors.lastname: Coombes
authors.forename: Jonas S
authors.initials: JS
authors.lastname: Almeida
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D008175:Lung Neoplasms; D009323:Natural Language Processing; D012106:Research / Q000458:organization & administration*; D012660:Semantics; D013781:Texas; D057170:Translational Research, Biomedical / Q000458:organization & administration*