[Flavone compound induces the apoptosis of prostate cancer cells].
Flavone compound is a polyphenolic compound widely existing in plants and has an extensive biological activity. In recent years, it has been found to have a significant anti-cancer effect, as in combating cell proliferation, inducing cell apoptosis, interfering with cellular signal transduction, increasing the activity of the cancer repressor gene and inhibiting the expression of oncogene. This paper reviews the mechanism by which flavone compound, induces the apoptosis of prostate cancer cells.
Zhang
Li
L
School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China. njust_zhangli@163.com
Shang
Xue-Jun
XJ
Huang
Yu-Feng
YF
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D047309:Flavones / Q000494:pharmacology*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D051381:Rats; D014407:Tumor Cells, Cultured
D047309:Flavones