title: Multidrug resistant tuberculosis co-existing with aspergilloma and invasive aspergillosis in a 50 year old diabetic woman: a case report.
abstract: Aspergilloma and invasive aspergillosis coexisting with multidrug resistant Mycobacterium tuberculosis (MDR-TB) in the same patient is a rare entity. We report a 50 year old South Indian woman, a diabetic, who presented to us with complaints of productive cough and hemoptysis for the past 2 months. She was diagnosed to have pulmonary tuberculosis 2 years ago for which she took irregular treatment. Lung imaging showed features of a thick walled cavity in the right upper lobe with an indwelling aspergilloma. She underwent a right lung upper lobe resection. Biopsy and culture of the resected specimen showed the coexistence of Aspergillus fumigatus and multi-drug resistant Mycobacterium tuberculosis. 2 blood cultures grew Aspergillus fumigatus. She was successfully treated with Voriconazole and anti tuberculous therapy against MDR-TB.
authors.affiliation: Department of General Medicine, Sri Ramachandra University, Chennai, India. anitakumar84@hotmail.com.
authors.forename: Anita A
authors.initials: AA
authors.lastname: Kumar
authors.forename: Ghanshyam Palamaner Subash
authors.initials: GP
authors.lastname: Shantha
authors.forename: Vijay
authors.initials: V
authors.lastname: Jeyachandran
authors.forename: K
authors.initials: K
authors.lastname: Rajkumar
authors.forename: Senthilkumar
authors.initials: S
authors.lastname: Natesan
authors.forename: Devasena
authors.initials: D
authors.lastname: Srinivasan
authors.forename: Leena Dennis
authors.initials: LD
authors.lastname: Joseph
authors.forename: Manjunath
authors.initials: M
authors.lastname: Sundaresan
authors.forename: Deepan
authors.initials: D
authors.lastname: Rajamanickam