title: Comparison of detailed and succinct cohort modelling approaches in a multi-regional evaluation of cervical cancer vaccination.
abstract: Mathematical models have been used extensively in the evaluation of chronic diseases and in exploring the health economics of vaccination. In this study, we examine the value of having two different cohort models based on similar assumptions, one comprehensive and one simplified, which can be used to evaluate the impact of cervical cancer vaccination. To compare models, we ran cost-effectiveness analyses in four geographical regions (Italy, the UK, Taiwan and Canada). We show that the models produce comparable results and therefore can be used independently. However, as they require different complexities of data inputs, they are more suited to different circumstances depending on the level of data inputs available or the complexity of the research question asked.
authors.affiliation: Health Economics and Outcomes Research, i3 Innovus, 1016-A Sutton Drive, Burlington, Ontario, Canada. Donna.DEBICKI@i3innovus.com
authors.forename: Donna
authors.initials: D
authors.lastname: Debicki
authors.forename: Nicole
authors.initials: N
authors.lastname: Ferko
authors.forename: Nadia
authors.initials: N
authors.lastname: Demarteau
authors.forename: Steve
authors.initials: S
authors.lastname: Gallivan
authors.forename: Chris
authors.initials: C
authors.lastname: Bauch
authors.forename: Andrea
authors.initials: A
authors.lastname: Anonychuk
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Mantovani
authors.forename: Stefano
authors.initials: S
authors.lastname: Capri
authors.forename: Cheng-Yang
authors.initials: CY
authors.lastname: Chou
authors.forename: Baudouin
authors.initials: B
authors.lastname: Standaert
authors.forename: Lieven
authors.initials: L
authors.lastname: Annemans
mesh_terms: D003365:Costs and Cost Analysis / Q000379:methods; D005260:Female; D006801:Humans; D017059:Models, Econometric; D002583:Uterine Cervical Neoplasms / Q000191:economics* / Q000517:prevention & control*; D014611:Vaccination / Q000191:economics*