title: Trochanteric soft tissue thickness and hip fracture in older men.
abstract: BACKGROUND
  Greater thickness of the tissue extending laterally from the greater trochanter has been associated with a lower risk of hip fracture in women. The effect of trochanteric soft tissue thickness on the risk of incident hip fracture has not been evaluated in men.
  
  
  METHODS
  We measured trochanteric soft tissue thickness by dual-energy x-ray absorptiometry for all incident hip fracture cases (n = 70) and 222 randomly selected noncases in older men (> or =65 yr) enrolled in the Osteoporotic Fractures in Men (MrOS) Study. Differences in tissue thickness between cases and controls were examined. Changes in fall force and factor-of-risk (the ratio of force from a sideways fall to femoral bone strength) associated with tissue thickness were determined. The relative risk for incident hip fracture per SD decrease in tissue thickness was calculated.
  
  
  RESULTS
  Mean trochanteric soft tissue thickness did not differ significantly between cases and noncases (29.1 +/- 11.9 vs 31.0 +/- 11.5 mm; P = 0.2). Although increased tissue thickness reduced both the estimates of fall force and the factor-of-risk, tissue thickness was not associated with the risk of hip fracture (age- and bone mineral density-adjusted relative risk per sd decrease in tissue thickness = 0.90; 95% confidence interval, 0.70-1.16).
  
  
  CONCLUSIONS
  In this study of elderly community-dwelling men, we found no significant association between trochanteric soft tissue thickness and incident hip fracture. Trochanteric soft tissue thickness in these men was less than previously reported in older women and may explain the difference between these results and those reported in women.
authors.affiliation: Bone and Mineral Unit, Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239-3098, USA.
authors.forename: Carrie M
authors.initials: CM
authors.lastname: Nielson
authors.forename: Mary L
authors.initials: ML
authors.lastname: Bouxsein
authors.forename: Sinara S
authors.initials: SS
authors.lastname: Freitas
authors.forename: Kristine E
authors.initials: KE
authors.lastname: Ensrud
authors.forename: Eric S
authors.initials: ES
authors.lastname: Orwoll
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition / Q000502:physiology; D005260:Female; D005269:Femur; D006620:Hip Fractures / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D016852:Housing for the Elderly / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology; D011379:Prognosis; D012680:Sensitivity and Specificity; D012727:Sex Characteristics; D012885:Skinfold Thickness; D015898:Tomography Scanners, X-Ray Computed