title: Evaluation of hand functions in women with polycystic ovary syndrome.
abstract: OBJECTIVE
  Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia and androgen levels are associated with muscle size and strength; thus we aimed to investigate the hand functions of women with PCOS.
  
  
  METHODS
  Thirty-seven patients with PCOS and 35 age-matched healthy women were included in the study as PCOS and control groups. Age, body mass index, dominant hand, physical activity level, lean/fat mass ratio, percentage of body fat, Beck Depression Inventory (BDI) score and Duruoz Hand Index (DHI) score were recorded. Hand grip and pinch strengths were tested in the dominant hand using a hand dynamometer and a pinch meter, respectively. Manual dexterity was tested by the grooved pegboard test. Serum concentrations of total testosterone, estradiol, dehydroepiandrosterone sulfate, follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone and progesterone were measured.
  
  
  RESULTS
  Patients with PCOS had high total testosterone levels (p < 0.001). There were no differences between groups in all of the hand strengths or dexterity. No correlations between hand parameters and hormones were found. DHI and BDI scores were high in the PCOS group (p = 0.002 and 0.039, respectively). There was a correlation between DHI and BDI scores. Depressive patients had higher BMI (p = 0.021) and body fat percentage (p = 0.05) than non-depressive patients in the PCOS group.
  
  
  CONCLUSIONS
  Hand strength and dexterity did not change in patients with PCOS. Depression risk increased especially in the patients with high BMI and affected hand functional status in PCOS.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Suleyman Demirel University, Isparta, Turkey. feraysoyupek@yahoo.com
authors.forename: Feray
authors.initials: F
authors.lastname: Soyupek
authors.forename: Mehmet
authors.initials: M
authors.lastname: Guney
authors.forename: Sevilay
authors.initials: S
authors.lastname: Eris
authors.forename: Sureyya
authors.initials: S
authors.lastname: Cerci
authors.forename: Sedat
authors.initials: S
authors.lastname: Yildiz
authors.forename: Tamer
authors.initials: T
authors.lastname: Mungan
mesh_terms: D000293:Adolescent; D000328:Adult; D050218:Body Fat Distribution; D015992:Body Mass Index; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006225:Hand / Q000502:physiology*; D018737:Hand Strength / Q000502:physiology; D006728:Hormones / Q000097:blood; D006801:Humans; D052581:Pinch Strength / Q000502:physiology; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D006728:Hormones