A case of Moyamoya syndrome and hemoglobin E/beta-thalassemia.
Moyamoya syndrome is a rare diagnosis that has been linked to a small number of hemoglobinopathies. Children with Moyamoya syndrome tend to present with transient ischemic attacks, mental deficiency, and/or neurological deficits. We describe a case of a 15-year-old Cambodian male with HbE/beta-thalassemia who was found to have left Moyamoya syndrome as part of an evaluation for growth hormone deficiency. The link between Moyamoya syndrome and HbE/beta-thalassemia may be multifactorial, but Moyamoya syndrome is an important consequence to consider in children with HbE/beta-thalassemia.
Parker
Torrey M
TM
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Ward
Leanne M
LM
Johnston
Donna L
DL
Ventureya
Enrique
E
Klaassen
Robert J
RJ
D006446:Hemoglobin E / Q000378:metabolism*; D006801:Humans; D007223:Infant; D018810:Magnetic Resonance Angiography; D008297:Male; D009072:Moyamoya Disease / Q000097:blood* / Q000150:complications* / Q000473:pathology; D017086:beta-Thalassemia / Q000097:blood* / Q000150:complications* / Q000473:pathology
D006446:Hemoglobin E