[Combination and transformation of toxin and blood stasis in etiopathogenesis of thrombotic cerebro-cardiovascular diseases].
According to the basic theory of traditional Chinese medicine (TCM), the pathogenetic factors such as platelet activation, adhesion, congregation and thrombosis fall into the category of blood stasis, while the pathological changes such as tissue necrosis, oxidative stress injury and inflammation, etc, are far beyond the etiological category of blood stasis. The toxin or the combination and transformation of toxin and blood stasis of TCM are involved in the pathogenesis of thrombotic cerebro-cardiovascular diseases. It is significant to recognize and stress the combination and transformation of toxin and stasis in pathogenicity so as to enrich TCM etiology and improve TCM clinical efficacy in the treatment of cerebro-cardiovascular and thrombotic diseases.
Shi
Da-zhuo
DZ
Cardiovascular Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China. shidz666@sohu.com
Xu
Hao
H
Yin
Hui-jun
HJ
Zhang
Jing-chun
JC
Chen
Ke-ji
KJ
D003328:Coronary Thrombosis / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000473:pathology; D008516:Medicine, Chinese Traditional / Q000379:methods*; D013927:Thrombosis / Q000175:diagnosis / Q000473:pathology*