[Research on optimization of forming techniques for Compound Tall Gastrodia Tuber drop pills by uniform design method].
OBJECTIVE
To select the best froming techniques for Compound Tall Gastrodia Tuber drop pills.


METHODS
According to the factors that affect the quality of drop pill, we selected four factors as temperature of drop solution, the variety of matrix, the ratio between drug and matrix, the dropping distance, and then we selected the RSD of weight of dripping pills and the roundness as index examination.


RESULTS
The optimum techniques as follows: the ratio between drug and matrix was 3 : 7, the temperature of drug solution was 80 degrees C, the dropping distance was 1 cm, the composition of matrix was PEG4000: PEG6000 = 1 : 1. The method adopted was steady and feasible.


CONCLUSIONS
It's feasible to seek the optimum techniques making Compound Tall Gastrodia Tuber drop pills by uniform design method.
Li
Jiang
J
Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China. lijiang2005zy@126.com
Geng
Juan
J
Gan
Yuan
Y
Qiu
De-Wen
DW
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D031668:Gastrodia / Q000737:chemistry*; D008863:Microspheres; D010946:Plants, Medicinal / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011786:Quality Control; D027343:Rhizome / Q000737:chemistry; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D011092:Polyethylene Glycols