title: [Treatment of osteoarthritis with drugs and other modalities].
abstract: There is an increasing incidence in osteoarthritis, particularly following the 5th life-decade. However, also young people may suffer from severe osteoarthritis, which is estimated to be the most common cause of disability in adults resulting in substantial economic burden. To this end, effective therapies are needed. Therapeutic options are very comprehensive, which are presented in this review as non-pharmacological, pharmacological and surgical treatment modalities. Treatment efficacy will be discussed with regard to alleviation of symptoms and potential prevention of disease progression according to the given evidence.
authors.affiliation: Klinik und Poliklinik für Innere Medizin I, Universität Regensburg, Regensburg, Deutschland. peter.haerle@klinik.uni-regensburg.de
authors.forename: P
authors.initials: P
authors.lastname: Härle
authors.forename: M
authors.initials: M
authors.lastname: Fleck
mesh_terms: D000284:Administration, Oral; D000880:Anthraquinones / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002809:Chondroitin Sulfates / Q000627:therapeutic use; D003131:Combined Modality Therapy; D000529:Complementary Therapies; D005944:Glucosamine / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use; D007270:Injections, Intra-Articular; D007595:Joint Prosthesis; D010003:Osteoarthritis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000880:Anthraquinones; D000893:Anti-Inflammatory Agents; C025292:diacerein; D006820:Hyaluronic Acid; D002809:Chondroitin Sulfates; D005944:Glucosamine