title: Applied chemistry of natural DNA.
abstract: Recently, natural DNA has emerged as an appealing biomacromolecule for functional materials. It is abundant and renewable, and possesses the well known double helix structure that promises many unique properties difficult to find in other polymers. Natural DNA has been applied in electronic, optical and biomaterials, as a catalyst for enantioselective reactions, and as a material for cleaning the environment. Most of the applications are based on combining DNA with other chemicals or nanoparticles by electrostatic binding, intercalation or groove binding. In this critical review article, recent developments in utilizing natural DNA are reviewed by focusing on three basic properties of DNA: the electrostatic property as a polyelectrolyte, selective affinity for small molecules, and biocompatibility (128 references).
authors.affiliation: Hokkaido Research Institute, Nissei Bio Co. Ltd., Megumino, Eniwa, Hokkaido, 061-1374, Japan. liuxd2006@infoseek.jp
authors.forename: XiangDong
authors.initials: X
authors.lastname: Liu
authors.forename: HongYan
authors.initials: H
authors.lastname: Diao
authors.forename: Norio
authors.initials: N
authors.lastname: Nishi
mesh_terms: D002412:Cations; D004247:DNA / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D008954:Models, Biological; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry
chemical_list: D002412:Cations; D004247:DNA