Micellar catalysis of Suzuki-Miyaura cross-couplings with heteroaromatics in water.
Pd-catalyzed couplings involving several heteroaromatic halides (bromides and chlorides) as well as boronic acids can be done under exceedingly mild conditions (between rt and 40 degrees C) in pure water using commercially available Pd catalysts and PTS, a nanomicelle-forming amphiphile.
Lipshutz
Bruce H
BH
Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106, USA. lipshutz@chem.ucsb.edu
Abela
Alexander R
AR
D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D008823:Micelles; D014867:Water / Q000737:chemistry*
D001897:Boronic Acids; D006571:Heterocyclic Compounds; D008823:Micelles; D014867:Water