Obstructive sleep apnoea risk profile and the risk of recurrence of atrial fibrillation after catheter ablation.
OBJECTIVE
The aim of this study was to identify the impact of obstructive sleep apnoea (OSA) on recurrence after catheter ablation of paroxysmal atrial fibrillation (AF).


RESULTS
One hundred and seventy-eight consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. The patients were divided into high risk (HR group) and low risk (LR group) for OSA group with Berlin questionnaire. Of the 178 patients, 104 (58.4%) were in the HR group and 74 (41.6%) were in the LR group. After a mean follow-up of 344 +/- 137 (91-572) days, 44 patients (24.7%) experienced recurrence, and the recurrence rate did not differ between the HR (25.0%) and LR groups (24.3%, P = 0.855). Cox analysis revealed that PV isolation was the only independent predictor of recurrence (hazard ratio 5.11, 95% confidence interval 1.42-18.47, P = 0.013). There was no significant difference in the incidence of complications between the HR and LR groups (2.9 vs. 1.9%, P = 0.729).


CONCLUSIONS
The recurrence rate and incidence of complications did not differ in patients with different risk profiles for OSA. The presence of OSA should not lower the decision threshold to choose an ablative procedure in paroxysmal AF.
Tang
Ri-Bo
RB
Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Chaoyang District, Beijing 100029, People's Republic of China.
Dong
Jian-Zeng
JZ
Liu
Xing-Peng
XP
Kang
Jun-Ping
JP
Ding
Shao-Fang
SF
Wang
Li
L
Long
De-Yong
DY
Yu
Rong-Hui
RH
Liu
Xiao-Hui
XH
Liu
Shuang
S
Ma
Chang-Sheng
CS
D001281:Atrial Fibrillation / Q000453:epidemiology* / Q000517:prevention & control*; D017115:Catheter Ablation; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D055502:Secondary Prevention; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology*; D016896:Treatment Outcome