[Assessment of total cardiovascular risk in adult persons of able-bodied age: lessons of the CROSSWORD study].
OBJECTIVE
To assess level of total risk of cardiovascular diseases (CVD) in a cohort of adults of ablebodied age and to study peculiarities of main risk factors (RF) and their combinations in subjects with different total risk of CVD.


METHODS
In CROSSWORD (assessment of total cardiovascular risk in adult persons of able-bodied age) study we collected data from 627 responders (207 men, 420 women, mean age 58.9 +/- 0.9 years). Technology of express calculation of total CVD risk based on age, sex, smoking status, levels of arterial preasure total cholesterol was tested during two large All Russia campaigns. Supplementary questioning concerning social status was also carried out and medications and somatic diseases were taken into consideration.


RESULTS
Hypercholesterolemia of various severity and arterial hypertension (AH) mainly first degree were found in 59 and 37% of responders, respectively. Every fifth responder was smoker. In most cases RF occurred in combinations. Two or 3 RF were registered in 42%, combinations of AH and hypercholesterolemia, smoking and hypercholesterolemia, AH and smoking, AH and smoking and hypercholesterolemia - in 24, 11.6, 1, and 5% of responders, respectively. Calculated total CVD risk was low or moderate in 72% (n=450), high in 14% (n=87), and very high in 14% (n=90) of subjects. Among women low and moderate CVD risk was almost twice more frequent than among men while every third man had very high CVD risk. Levels of RF within groups with different total risk turn out to be inhomogeneous. Among supplementary RF only abdominal obesity closely correlated with total CVD risk. No significant association was found between hereditary load of CVD, status of education and total CVD risk.
Mamedov
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MN
Deev
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AD
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology