Cell contact-inhibition signaling as part of wound-healing processes in brain.
Cell contact-dependent signaling is a major regulatory mechanism in the organization of developing tissues and in the reorganization (post-injury responses) of specialized tissues in multicellular organisms. In this review we contribute to the further understanding of post-injury recovery processes in adult nervous tissue. We emphasize evidence that supports the involvement of cell contact-inhibition signaling in the cell proliferation, growth and differentiation that occurs during healing and neural reorganization after brain damage.
Lanosa
Ximena A
XA
Unidad de Neurobiología Aplicada, CEMIC, Buenos Aires, Argentina.
Colombo
Jorge A
JA
D002450:Cell Communication / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology; D049109:Cell Proliferation; D003260:Contact Inhibition / Q000502:physiology*; D005911:Gliosis / Q000503:physiopathology; D009416:Nerve Regeneration / Q000502:physiology*; D009457:Neuroglia / Q000166:cytology / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*