title: UNTREATED TRANSIENT LONGER THAN 7-DAY CHAT, CIRCADIAN HYPER-AMPLITUDE TENSION, IN A 7-YEAR PERSPECTIVE.
abstract: The case report presented herein aims at promoting the awareness in medical, notably cardiological, practice of the importance of, first, collecting at least a week-long record of around-the-clock measurements of blood pressure (BP) and heart rate (HR) (and a much longer record if the 7 day record so indicates) and, second, of analysing the data chronobiologically in the light of reference values specified as a function of time, gender and age as a minimum. In addition to diagnosing deviations in a chronome (time structure)-adjusted mean value, a chronobiological approach identifies abnormalities in the variability of BP and/or HR, gauged by the circadian characteristics (double amplitude and acrophase, measures of the extent and timing of predictable change within a cycle) and by the standard deviation. A woman in presumably good health was 60 years of age at the start of intermittent monitoring over a 7 year span. The case report illustrates the extent to which a decision based on single BP readings and even on 24 hour averages may be misleading. Treatment based on an initial week-long monitoring may benefit from continued long-term monitoring.
authors.affiliation: Halberg Chronobiology Center, University of Minnesota, USA.
authors.forename: O
authors.initials: O
authors.lastname: Schwartzkopff
authors.forename: G
authors.initials: G
authors.lastname: Cornélissen
authors.forename: C
authors.initials: C
authors.lastname: Halpin
authors.forename: G
authors.initials: G
authors.lastname: Katinas
authors.forename: J
authors.initials: J
authors.lastname: Siegelová
authors.forename: B
authors.initials: B
authors.lastname: Fišer
authors.forename: J
authors.initials: J
authors.lastname: Dušek
authors.forename: F
authors.initials: F
authors.lastname: Halberg