[Experimental study of the bioresorbable collagen membrane used for guided bone regeneration around dental implants].
OBJECTIVE
To investigate the effects of using guided bone regeneration (GBR) technique with an bioresorbable collagen membrane for repairing bone defects around dental implants.


METHODS
In 12 mongrel dogs, pure titanium implants were immediately implanted in mandibles after extraction of the mandibular third and fourth premolars of both sides, in which standard bone defects of 3 mm x 3 mm x 5 mm were created at mesial side of the implants. The defects on right side were covered with Co membrane, the left side was uncovered as control. The dogs were sacrificed 1, 2, 4, 6 months postoperatively. The specimens were removed and studied by gross observation, X-ray radiograph, histological examination, scanning electron microscope (SEM) and pull-out test.


RESULTS
The quantity and quality of new bone formation in experimental side which bone defects covered with Co membrane were much better than that in the control side.


CONCLUSIONS
With the biodegradable property and excellent biocompatibility, Co membrane can be used for guided bone regeneration to promote the bone repair progress, and the promotion acts mainly at early stage of bone healing.
Fei
Wei
W
Dept. of Oral and Maxillofacial Surgery, Sichuan Provincial People's Hospital, Chengdu, China.
Yang
Xiao-min
XM
Li
Zheng
Z
Yin
Ming-ping
MP
Shen
Zhi-hao
ZH
Liao
Chu-hang
CH
D000818:Animals; D001861:Bone Regeneration; D003094:Collagen; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal; D008334:Mandible; D008567:Membranes, Artificial; D014025:Titanium
D015921:Dental Implants; D008567:Membranes, Artificial; D003094:Collagen; D014025:Titanium