title: Assessing the performance of a bdelloid rotifer Philodina acuticornis odiosa acute toxicity assay.
abstract: A bioassay using the bdelloid rotifer, Philodina acuticornis odiosa, was evaluated for use as a standard test method for direct toxicity assessment testing in the Australasian region. Philodina acuticornis odiosa was found to be relatively tolerant to phenol (24 h LC50, 142 mg/L). The mortality endpoint was both reliable and repeatable (the coefficients of variation for mortality at the 24 h LC50 concentration ranged from 11%-24% (n = 8)), sufficiently low to warrant further testing with a range of reference toxicants, so that this organism can be included for use as a regulatory test in Australasia.
authors.affiliation: School of Applied Sciences, RMIT University Bundoora West Campus, Bundoora, Vic, Australia.
authors.forename: T
authors.initials: T
authors.lastname: Hagen
authors.forename: G
authors.initials: G
authors.lastname: Allinson
authors.forename: A
authors.initials: A
authors.lastname: Wightwick
authors.forename: D
authors.initials: D
authors.lastname: Nugegoda
mesh_terms: D000818:Animals; D019800:Phenol / Q000633:toxicity; D012403:Rotifera / Q000187:drug effects*; D018675:Toxicity Tests / Q000592:standards*
chemical_list: D019800:Phenol