title: [Two cases of advanced hepatocellular carcinoma (HCC) effectively treated by oral UFT administration].
abstract: Case 1 was operated for HCC in September, 2002. After then TAE was performed two times for remnant liver recurrence. A year later, huge recurrence of left liver and tumor thrombus in IVC and PV were detected. After starting oral UFT administration, AFP lever went down within normal limit and tumor thrombus and early enhancement disappeared by CT scan. But after about a year, AFP level went up and TAE was performed two times, the patient died in July, 2007. Case 2 was operated for HCC in August, 2004. Re-operation was performed for recurrence of remnant liver in January, 2006. But recurrence was detected and TAE was performed in November. Ascites and leg edema appeared in June, 2007. Many recurrences of right liver, tumor thrombus in right hepatic vein and hilar hepatic lymph node were detected, UFT administration was started. After then, AFP level went down and tumor size reduced markedly by CT scan. We presents two cases effectively treated by oral UFT administration.
authors.affiliation: Dept. of Surgery, Omachi City General Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takagi
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Misawa
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Iinuma
authors.forename: Yuji
authors.initials: Y
authors.lastname: Uchikawa
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014498:Uracil / Q000008:administration & dosage / Q000627:therapeutic use; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D000509:alpha-Fetoproteins; D005641:Tegafur; D014498:Uracil