title: Symmetric truncal aplasia cutis congenita following multifetal reduction of a sextuplet pregnancy.
abstract: Aplasia cutis congenita (ACC) in a symmetric, stellate pattern on the trunk or extremities is classically associated with a fetus papyraceus. We report symmetric truncal ACC in a neonate born of a sextuplet pregnancy that had been reduced to twins. This case highlights truncal ACC as a consequence of modern reproductive medicine.
authors.affiliation: Departments of Dermatology and Pediatrics, New York University School of Medicine, New York, NY, USA.
authors.forename: Julie V
authors.initials: JV
authors.lastname: Schaffer
authors.forename: Dorota A
authors.initials: DA
authors.lastname: Popiolek
authors.forename: Seth J
authors.initials: SJ
authors.lastname: Orlow
mesh_terms: D000328:Adult; D004476:Ectodermal Dysplasia / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D018607:Pregnancy Reduction, Multifetal / Q000009:adverse effects* / Q000379:methods*; D012016:Reference Values; D014429:Twins, Dizygotic; D000509:alpha-Fetoproteins / Q000302:isolation & purification
chemical_list: D000509:alpha-Fetoproteins