title: [Hematological, serum biochemical and serological profile of Felis domesticus with experimental lagochilascariosis].
abstract: The present study evaluated the hemogram, different proteins, plasma enzymes, serum enzymes and specific antibody production of Felis domesticus experimentally infected by Lagochilascaris minor. The infected animals were seen to present increased total leukocytes (particularly eosinophils), decreased platelet counts, increased aspartate-aminotransferase and alanine-aminotransferase and, especially, the presence of specific IgG antibodies against antigens of the parasite. The reaction with crude extract of adult parasites was shown to be more specific, thereby enabling serum discrimination between the animals: non-infected, infected with other parasites and infected with lagochilascariosis. This is the first description of the standardization of a serological reaction for diagnosing lagochilascariosis in Felis domesticus.
authors.affiliation: Departamento de Imunologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, GO.
authors.forename: Mariana Félix de Souza
authors.initials: MF
authors.lastname: Prudente
authors.forename: Kelly Cristine
authors.initials: KC
authors.lastname: Lima
authors.forename: Mara Silvia
authors.initials: MS
authors.lastname: Carvalhaes
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D017191:Ascaridida Infections / Q000097:blood / Q000175:diagnosis* / Q000201:enzymology; D001199:Ascaridoidea / Q000276:immunology / Q000302:isolation & purification*; D015415:Biomarkers / Q000032:analysis; D002415:Cats / Q000469:parasitology*; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000097:blood*; D051379:Mice; D008810:Mice, Inbred C57BL
chemical_list: D000913:Antibodies, Protozoan; D015415:Biomarkers; D007074:Immunoglobulin G