title: Inflammatory demyelinating neuropathies and neuropathies associated with monoclonal gammopathies: treatment update.
abstract: This review focuses on recent data regarding inflammatory demyelinating neuropathies and neuropathies associated with monoclonal gammopathies. We describe both acute and chronic inflammatory neuropathies, and we discuss conditions ranging from mostly cell-mediated to antibody-mediated disorders. These diseases are characterized by proximal and distal sensory motor involvement. Treatments are based on immune-modulation and/or immune-suppression. Work-up sequence and therapeutical modes are discussed in the light of recently published data, with a special interest on new treatment modalities.
authors.affiliation: Department of Neurology, University of Basel, Basel, Switzerland. asteck@uhbs.ch
authors.forename: Andreas J
authors.initials: AJ
authors.lastname: Steck
authors.forename: Adam
authors.initials: A
authors.lastname: Czaplinski
authors.forename: Susanne
authors.initials: S
authors.lastname: Renaud
mesh_terms: D000818:Animals; D003449:Cryoglobulinemia / Q000150:complications / Q000473:pathology / Q000628:therapy; D003711:Demyelinating Diseases / Q000473:pathology / Q000628:therapy*; D006023:Glycoproteins / Q000276:immunology; D020275:Guillain-Barre Syndrome / Q000473:pathology / Q000628:therapy; D015417:Hereditary Sensory and Motor Neuropathy / Q000473:pathology / Q000628:therapy; D006801:Humans; D009101:Multiple Myeloma / Q000150:complications / Q000473:pathology / Q000628:therapy; D009186:Myelin Sheath / Q000276:immunology; D010026:Osteosclerosis / Q000150:complications / Q000473:pathology / Q000628:therapy; D016878:POEMS Syndrome / Q000150:complications / Q000473:pathology / Q000628:therapy; D010265:Paraproteinemias / Q000145:classification / Q000473:pathology / Q000628:therapy*; D011115:Polyneuropathies / Q000473:pathology / Q000628:therapy
chemical_list: D006023:Glycoproteins