Treatment experiences of testicular cancer in Hispanic patients with Down's syndrome at the National Cancer Institute of Mexico.
We present 4 case studies of patients with Down's syndrome and testicular germ-cell cancer, treated with conventional methods at the National Cancer Institute of Mexico, with similar outcomes as patients without this syndrome. There are several reports of testicular cancer arising in patients with Down's syndrome worldwide, mainly from Caucasian populations. We discuss some theories about the association and the possible increase of incidence.
Aguilar-Ponce
Jose Luis
JL
Department of Medical Oncology, Instituto Nacional de Cancerología (INCan), Distrito Federal, México. oncoincan@hotmail.com
Vidal-Millán
Silvia
S
Molina-Calzada
Carlos
C
Chilaca-Rosas
Fatima
F
Martínez-Cedillo
Jorge
J
Cruz-López
Juan Carlos
JC
D000015:Abnormalities, Multiple; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003456:Cryptorchidism / Q000150:complications; D004314:Down Syndrome / Q000150:complications*; D005047:Etoposide / Q000008:administration & dosage; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008800:Mexico; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications* / Q000473:pathology / Q000556:secondary / Q000601:surgery; D009919:Orchiectomy; D012074:Remission Induction; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy / Q000556:secondary; D018239:Seminoma / Q000150:complications / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin