Impediments to prenatal diagnosis for beta thalassaemia: experiences from Pakistan.
OBJECTIVE
To investigate the practices of parents of beta thalassaemia children towards utilization of prenatal diagnosis (PND) in Pakistan.


METHODS
A cross-sectional study was done between April and September 2007 at two thalassaemia treatment centers in Rawalpindi and Islamabad. Simple random sampling was employed to interview 215 parents of thalassaemic children. Parents of thalassaemic children who were not planning to have any more children were excluded from the study. A structured questionnaire with preassigned values was developed for collection of data.


RESULTS
Out of the 215 respondents, 149 (69%) families had a pregnancy following the birth of the registered thalassaemic child. Among 149 couples, 90 (60%) did not request PND. The main reasons for underutilization of PND included lack of awareness (23%), high cost (23%), poor access (17%), delay in seeking (16%) and advice against the test (12%). A significant improvement in the use of PND was observed with increasing mother's education (p < 0.016).


CONCLUSIONS
PND for thalassaemia is available in Pakistan for over a decade but its use remains limited. There is a need to increase its utilization by addressing various impediments noted in this study.
Naseem
Sajida
S
Armed Forces Post Graduate Medical Institute, Department of Community Health Sciences, Rawalpindi, Pakistan. sajidanaseem@gmail.com
Ahmed
Suhaib
S
Vahidy
Farhaan
F
D000465:Algorithms; D001364:Awareness; D003430:Cross-Sectional Studies; D004522:Educational Status; D005191:Family Characteristics; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D010154:Pakistan; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000523:psychology / Q000706:statistics & numerical data*; D017086:beta-Thalassemia / Q000175:diagnosis*