title: Tandem conjugate addition-elimination reaction promoted by chiral pyrrolidinyl sulfonamide (CPS).
abstract: Chiral pyrrolidinyl sulfonamides have been found to promote the conjugate addition-elimination reaction between activated allylic bromides and 1,3-dicarbonyl compounds with high enantioselectivities and the highly functionalised products can be used to generate a variety of interesting enantiomerically pure compounds via simple transformations.
authors.affiliation: Department of Chemistry, National University of Singapore, Singapore.
authors.forename: Junye
authors.initials: J
authors.lastname: Xu
authors.forename: Xiao
authors.initials: X
authors.lastname: Fu
authors.forename: Ruijuan
authors.initials: R
authors.lastname: Low
authors.forename: Yong-Peng
authors.initials: YP
authors.lastname: Goh
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Jiang
authors.forename: Choon-Hong
authors.initials: CH
authors.lastname: Tan
mesh_terms: D006842:Hydrocarbons, Brominated / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D008314:Malonates / Q000737:chemistry; D015394:Molecular Structure; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D006842:Hydrocarbons, Brominated; D007659:Ketones; D008314:Malonates; D011759:Pyrrolidines; D013449:Sulfonamides