Successful treatment of ligneous gingivitis with warfarin.
Ligneous gingivitis is a rare condition characterized by inflammation and nodular gingival enlargement secondary to fibrin deposits in the gingival that results from plasminogen deficiency. Several therapeutic approaches have been used with limited success. We report a case of a patient with homozygous plasminogen deficiency and ligneous gingivitis that was initially refractory to local care and systemic antibiotics, but later improved with the addition of warfarin.
Fine
Gregg
G
Department of Medicine, Hematology/Oncology Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. gfine@bidmc.harvard.edu
Bauer
Kenneth
K
Al-Mohaya
Maha
M
Woo
Sook-Bin
SB
D000925:Anticoagulants / Q000627:therapeutic use*; D020147:Coagulation Protein Disorders / Q000150:complications*; D005260:Female; D005891:Gingivitis / Q000188:drug therapy* / Q000209:etiology*; D006720:Homozygote; D006801:Humans; D008875:Middle Aged; D010958:Plasminogen / Q000172:deficiency*; D002575:Uterine Cervicitis / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use*
D000925:Anticoagulants; D014859:Warfarin; D010958:Plasminogen