First isolation of Clostridium difficile PCR-ribotype 027/toxinotype III in Poland.
Of 175 Clostridium difficile strains isolated from patient hospitalized in one academic hospital in Warsaw between 2005-2006, one isolate belonged to PCR-ribotype 027/toxinotype III. This isolate had tcdA, tcdB, binary toxin genes (cdtA and cdtB), a 18-bp deletion and a 1 bp deletion at 117 position in the tcdC gene. Antimicrobial susceptibility tests revealed high level resistance to erythromycin, moxifloxacin and gatifloxacin. This is a first report of the 027 strain of C. difficile in Poland.
Pituch
Hanna
H
Chair and Department of Medical Microbiology, The Medical University of Warsaw, Warsaw, Poland. hanna.pituch@ib.amwaw.edu.pl
Bakker
Dennis
D
Kuijper
Ed
E
Obuch-Woszczatyński
Piotr
P
Wultańska
Dorota
D
Nurzyńska
Grazyna
G
Bielec
Anna
A
Bar-Andziak
Ewa
E
Łuczak
Mirosław
M
D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016360:Clostridioides difficile / Q000145:classification* / Q000302:isolation & purification*; D024901:Drug Resistance, Multiple, Bacterial; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D011044:Poland / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D021521:Ribotyping
D000900:Anti-Bacterial Agents