title: [Inappropriate low glycated hemoglobin and hemolysis].
abstract: Hemoglobin A1c (HbA1c), measured regularly in the patients with diabetes, is the major form of stable glycated hemoglobin and has to be maintained below 6.5% to prevent or decrease the risk of chronic complications. HbA1c reflects mean blood glucose levels of the previous 3 months. We report the case of a particularly low HbA1c in a diabetic patient despite high plasma glucose levels, that was induced by auto-immune hemolysis related to an Evans syndrome. All hemolytic disorders can be responsible for falsely reassuring HbA1c values. Clinicians must be aware that hematologic status has to be considered for the correct interpretation of HbA1c results.
authors.affiliation: Service de médecine interne, hôpital Nord, 42055 Saint-Etienne cedex 2, France. alexa.debard@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Debard
authors.forename: S
authors.initials: S
authors.lastname: Charmion
authors.forename: S
authors.initials: S
authors.lastname: Ben Ameur
authors.forename: J-B
authors.initials: JB
authors.lastname: Gaultier
authors.forename: P
authors.initials: P
authors.lastname: Cathébras
mesh_terms: D000369:Aged, 80 and over; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis*; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D013577:Syndrome
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human