title: [Repercussions of premature rupture of fetal membranes on neonatal morbidity and mortality].
abstract: The objective of this study was to analyze factors associated with death and survival with sequelae in neonates after premature rupture of fetal membranes (PROM). An observational historical cohort study analyzed charts of patients with PROM at < or = 34 weeks gestation. The variables were compared with neonatal death and survival with sequelae as the outcomes. In both groups, the data were submitted to bivariate analysis, and the variables showing significance were submitted to logistic regression. The final multivariate model for fetal death showed statistical significance for the following: chorioamnionitis; 5-minute Apgar score < or = 5; birth weight < or = 1,000g; and cardiopulmonary resuscitation. Survival with sequela was associated with: cervical colonization; patent ductus arteriosus; 5-minute Apgar score < or = 5; and birth weight < or = 1,000g. Infections, very low birth weight, and peripartum asphyxia were the principal variables associated with the target outcomes among newborns from gestations involving PROM.
authors.affiliation: Hospital Geral de Bonsucesso, Rio de Janeiro, Brasil. glauciomp@hotmail.com
authors.forename: Glaucio de Moraes
authors.initials: Gde M
authors.lastname: Paula
authors.forename: Luiz Guilherme Pessoa da
authors.initials: LG
authors.lastname: Silva
authors.forename: Maria Elizabeth Lopes
authors.initials: ME
authors.lastname: Moreira
authors.forename: Olga
authors.initials: O
authors.lastname: Bonfim
mesh_terms: D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D002821:Chorioamnionitis / Q000209:etiology; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000517:prevention & control; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D009017:Morbidity; D015999:Multivariate Analysis; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult