Identification of a new HLA DRB1 allele (HLA-DRB1*1167) in a potential hematopoietic stem cell donor from Iraqi Kurdistan.
High-resolution polymerase chain reaction sequence-specific primer typing and sequence-based typing of the human leukocyte antigen (HLA) gene DRB1 in a potential hematopoietic stem cell donor of Kurdish ethnicity revealed a new allelic variant of HLA-DRB1*11. The sequence was named DRB1*1167, and comparison with previously described DRB1 alleles demonstrated a mixed pattern shared with some DRB1*08 alleles.
Testi
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Centro Regionale Trapianti di Riferimento per i Trapianti di Organi, Tessuti e Cellule, Cattedra di Genetica Medica, Università degli Studi di Cagliari, Cagliari, Italy.
Lai
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Alba
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Andreani
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Carcassi
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D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006412:Hematopoietic Stem Cells; D006801:Humans; D007493:Iraq; D019520:Living Donors; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C538925:HLA-DRB1*11:67 antigen