title: Improving aminoglycoside dosing through computerized clinical decision support and pharmacy therapeutic monitoring systems.
abstract: Dosing errors and inadequate laboratory monitoring of aminoglycosides may lead to significant adverse drug events. Correctly prescribing aminoglycosides requires familiarity with multiple mathematically complicated dosing and laboratory monitoring protocols. We developed a clinical decision support system for ordering aminoglycosides which is integrated into a computerized provider order entry system. To complement the ordering tool, we implemented a real-time tracking application to allow the pharmacist-staffed therapeutic drug monitoring service to follow patients prescribed aminoglycosides.
authors.affiliation: Vanderbilt University, Nashville, Tennessee, USA.
authors.forename: Ira E
authors.initials: IE
authors.lastname: Phillips
authors.forename: Cori
authors.initials: C
authors.lastname: Nelsen
authors.forename: Josh
authors.initials: J
authors.lastname: Peterson
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Sullivan
authors.forename: Lemuel R
authors.initials: LR
authors.lastname: Waitman
mesh_terms: D000617:Aminoglycosides / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001424:Bacterial Infections / Q000188:drug therapy*; D020000:Decision Support Systems, Clinical; D016903:Drug Monitoring / Q000379:methods*; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D006801:Humans; D050316:Medical Order Entry Systems; D008510:Medication Systems, Hospital; D013714:Tennessee
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents