Comparison of the performances of two in-house rapid methods for antitubercular drug susceptibility testing.
Resistance to rifampin (rifampicin), isoniazid, and streptomycin of 69 Mycobacterium tuberculosis isolates was analyzed by an in-house method based on mycobacteriophage D29 and a colorimetric micromethod. Both methods showed sensitivity and specificity values ranging from 93% to 100%. These simple methods offer an option for drug resistance assessment of M. tuberculosis.
de la Iglesia
Agustina I
AI
Cátedra de Microbiología, Universidad Nacional de Rosario, Argentina.
Stella
Emma J
EJ
Morbidoni
Héctor R
HR
D000995:Antitubercular Agents / Q000494:pharmacology*; D003124:Colorimetry; D008826:Microbial Sensitivity Tests / Q000191:economics / Q000379:methods*; D009160:Mycobacteriophages / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D012015:Reference Standards; D015203:Reproducibility of Results
D000995:Antitubercular Agents