[Study the inhibitory effects of three oral actinomyces on growth of oral Candida albicans in vitro].
OBJECTIVE
The aim of this study was to investigate whether the three species of oral Actinomyces have inhibitory effects on the growth of oral Candida albicans in vitro.


METHODS
Straight o'clock method was used to observe the bacteriostasis circle. Reverse o'clock and mixed culture method were used to study the quantitative changes of Candida albicans colony respectively.


RESULTS
(1) None of the groups had been viewed the bacteriostasis circle. (2) Compared with control groups, there was a significant decrease of Candida albicans colony on Actinomyces viscosus TPY soft agar (P < 0.05). Actinomyces naeslundii and Actinomyces odontolyticus TPY soft agar were both devoid of obvious Candida albicans colony (P < 0.01). The former group (Actinomyces viscosus) and the two latter groups (Actinomyces naeslundii and Actinomyces odontolyticus) showed a striking contrast (P < 0.01). (3) Compared with control groups, a decrease of Candida albicans showed up in the mixed culture, and the difference was significant (P < 0.05). The discrepancies among the three experimental groups were of no statistical value (P > 0.05).


CONCLUSIONS
Oral Actinomyces viscosus, Actinomyces naeslundii and Actinomyces odontolyticus could inhibit the growth of Candida albicans in vitro. However, which of them contributed more to the inhibitory effects was still not affirmed.
Li
Duo
D
State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Xiao
Xiao-rong
XR
Zhu
Zhu
Z
Ren
Qian
Q
Hu
Tao
T
Gong
Qi-mei
QM
Zhou
Hong-mei
HM
D000190:Actinomyces; D016924:Actinomyces viscosus; D002176:Candida albicans; D066298:In Vitro Techniques