title: Endometrial polyps and associated factors in Danish women aged 36-74 years.
abstract: OBJECTIVE
  To identify factors associated with endometrial polyps.
  
  
  METHODS
  Case-control study of 140 women with endometrial polyps and 367 controls. Information on potentially associated factors was obtained by a validated questionnaire.
  
  
  RESULTS
  In an age-adjusted logistic regression model, the following was positively associated with endometrial polyps: current use of hormone therapy (odds ratio, 2.81; 95% CI, 1.29-6.13) and being overweight (body mass index > 25 kg/m(2)) (odds ratio, 2.06; 95% CI, 1.12-3.79) (postmenopausal women). Negatively associated was use of oral contraceptive pills (odds ratio, 0.20; 95% CI, 0.06-0.66). Histopathology diagnosed benign endometrial polyps (n = 137), polyp with premalignant disease (n = 3), and benign polyp with concomitant complex hyperplasia/endometrial cancer (n = 3).
  
  
  CONCLUSIONS
  Being overweight and current use of hormone therapy in postmenopausal women were positively associated, whereas the use of oral contraceptive pills was negatively associated with endometrial polyps. Hypertension and cervical polyps were not associated with endometrial polyps. Endometrial polyps were infrequently related to premalignant and malignant disease.
authors.affiliation: Department of Obstetrics and Gynecology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Eva
authors.initials: E
authors.lastname: Dreisler
authors.forename: Soren Stampe
authors.initials: SS
authors.lastname: Sorensen
authors.forename: Gunnar
authors.initials: G
authors.lastname: Lose
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D003718:Denmark; D016889:Endometrial Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008593:Menopause; D008875:Middle Aged; D011127:Polyps; D011446:Prospective Studies