title: Further evidence of spontaneous cure in human Chagas disease.
abstract: An acute case of Chagas disease was studied in 1944, with clinical and laboratory follow-up until 2007, in Bambuí, Minas Gerais, Brazil. A five-year-old girl living in a rural hut that was highly infested with Triatoma infestans presented a febrile clinical condition compatible with the acute form of trypanosomiasis. She presented a positive thick blood smear, but never again showed serological and/or parasitological evidence of Trypanosoma cruzi infection, on several occasions. This patient never received any specific treatment and, to this day, she remains completely asymptomatic, with normal findings from clinical, electrocardiographic, X-ray and echocardiographic examinations.
authors.affiliation: Fundação Oswaldo Cruz, Belo Horizonte, MG. jcpdias@cpqrr.fiocruz.br
authors.forename: João Carlos Pinto
authors.initials: JC
authors.lastname: Dias
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Dias
authors.forename: Olindo Assis
authors.initials: OA
authors.lastname: Martins-Filho
authors.forename: Olindo M
authors.initials: OM
authors.lastname: Filho
authors.forename: Danielle
authors.initials: D
authors.lastname: Vitelli-Avelar
authors.forename: Dalmo
authors.initials: D
authors.lastname: Correia
authors.forename: Eliane
authors.initials: E
authors.lastname: Lages
authors.forename: Aluízio
authors.initials: A
authors.lastname: Prata
mesh_terms: D000208:Acute Disease; D000368:Aged; D014355:Chagas Disease; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D012075:Remission, Spontaneous