title: A case of malignant primary non-Hodgkin's lymphoma in skeletal muscle treated by exclusive chemotherapy.
abstract: Malignant non-Hodgkin's lymphoma (MNHL) is a frequent tumour but a primary intra-muscular location is exceptional. Standard treatment combines wide surgical removal with chemotherapy and radiotherapy. The functional consequences of this large excision are sometimes very unsatisfactory. We report the case of an intra-muscular MNHL of the posterior and internal part of the thigh. The diagnostic was established thanks to selective biopsies. The treatment was purely medical and conservative with chemotherapy after a multidisciplinary oncological discussion. Three years after the treatment, the general state of health is excellent with no signs of local or remote recurrence.
authors.affiliation: Service Chirurgie Orthopédique et Traumatologique, CHU Rangueil, 1 avenue Jean Poulhès, 31059 Toulouse, France. jean-michel.laffosse@wanadoo.fr
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Laffosse
authors.forename: Anne
authors.initials: A
authors.lastname: Gomez-Brouchet
authors.forename: François
authors.initials: F
authors.lastname: Molinier
authors.forename: Philippe
authors.initials: P
authors.lastname: Chiron
authors.forename: Henri
authors.initials: H
authors.lastname: Roché
authors.forename: Jean
authors.initials: J
authors.lastname: Puget
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D018572:Disease-Free Survival; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000737:chemistry / Q000188:drug therapy* / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D013848:Thigh / Q000473:pathology; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone