title: [Pyogenic-liver abscess: diagnosis and management].
abstract: Pyogenic-liver abscesses are due to bacteria mostly from the portal and biliary tracts. There is usually only one located in the right liver, but they may be found in the left liver, be multiple or multilocular. Diagnosis, based on ultrasound and/or computed tomography scan, is confirmed by percutaneous-needle aspiration to identify the bacteria causing the disease. Global management includes the treatment of sepsis and the aetiology of the liver abscess: biliary lithiasis, diverticular disease, colon cancer, appendicitis or other intra-abdominal infections. However, no cause is found in 20% of cases. Treatment is based on antibiotics and, sometimes, percutaneous drainage while the cause may be treated immediately or later if the sepsis is controlled. Interventional radiology is often used. Surgery may be performed in case of failure of initial treatment and to cure the cause of the abscess. Prognosis may be poor, especially if there are associated-risk factors, such as diabetes and immunodepression, even though the outcome has improved with a multidisciplinary approach.
authors.affiliation: Département de chirurgie viscérale et digestive, CHU de Caen, avenue de Côte-de-Nacre, 14000 Caen, France. chiche-l@chu-caen.fr
authors.forename: L
authors.initials: L
authors.lastname: Chiche
authors.forename: S
authors.initials: S
authors.lastname: Dargère
authors.forename: V
authors.initials: V
authors.lastname: Le Pennec
authors.forename: C
authors.initials: C
authors.lastname: Dufay
authors.forename: B
authors.initials: B
authors.lastname: Alkofer
mesh_terms: D003663:Decision Trees; D006801:Humans; D046290:Liver Abscess, Pyogenic / Q000175:diagnosis* / Q000628:therapy*; D013492:Suppuration