title: Spleen rupture due to primary angiosarcoma: a case report.
abstract: A case of a 79-year-old female with rupture of the spleen due to primary angiosarcoma is presented. Symptoms were non-specific. Diagnosis was based on histology postoperatively. Primary angiosarcoma of the spleen is a very rare and aggressive neoplasm with a high metastatic rate and almost uniformly fatal. Due to small number of reported cases, there are no guidelines concerning adjuvant or palliative treatment or any beneficial protocols of chemotherapy or radiotherapy up to date. Splenectomy prior to rupture seems to have a positive impact on long-term survival.
authors.affiliation: 2nd Department of Surgery, Aristoteles University of Thessaloniki, G. Gennimatas General Hospital, Thessaloniki, Greece.
authors.forename: Ioannis M
authors.initials: IM
authors.lastname: Koutelidakis
authors.forename: Panagiotis Z
authors.initials: PZ
authors.lastname: Tsiaousis
authors.forename: Basilios Th
authors.initials: BT
authors.lastname: Papaziogas
authors.forename: Aristeides G
authors.initials: AG
authors.lastname: Patsas
authors.forename: Stefanos K
authors.initials: SK
authors.lastname: Atmatzidis
authors.forename: Konstantinos S
authors.initials: KS
authors.lastname: Atmatzidis
mesh_terms: D000368:Aged; D005260:Female; D006394:Hemangiosarcoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D013160:Splenic Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013161:Splenic Rupture / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed