title: [Cognitive dysfunction and brain perfusion in patients with arterial hypertension: possibilities of pharmacological therapy].
abstract: The study included 31 patients with essential hypertension. Twenty-four hours blood pressure monitoring, assessment of neurological status and cognitive functions as well as single photon emission tomography were performed at baseline and three months after treatment. The beta-blocker therapy during 3 months exerted a positive effect on the brain perfusion that resulted in the improvement of cognitive function - verbal and visual memory, attention, psychomotor speed, thinking and visuoconstruction.
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Efimova
authors.forename: V I
authors.initials: VI
authors.lastname: Chernov
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Efimova
authors.forename: N L
authors.initials: NL
authors.lastname: Afanas'eva
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Lishmanov
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001921:Brain / Q000098:blood supply* / Q000503:physiopathology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012720:Severity of Illness Index
chemical_list: D000959:Antihypertensive Agents