title: Focus issue: an expanding world for TGF-beta signaling.
abstract: The complexity of the signaling network that is initiated by members of the transforming growth factor-beta (TGF-beta) superfamily continues to increase. In addition, Smads, which were originally identified as key transducers of TGF-beta signals, are beginning to emerge as players in other TGF-beta-independent processes. Perspectives in this issue, as well as highlights from a recent meeting on TGF-beta and select resources from the Archives, spotlight this emerging complexity.
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D021581:Active Transport, Cell Nucleus; D000818:Animals; D006801:Humans; D008024:Ligands; D015398:Signal Transduction / Q000502:physiology*; D051785:Smad Proteins / Q000502:physiology; D016212:Transforming Growth Factor beta / Q000502:physiology*
chemical_list: D008024:Ligands; D051785:Smad Proteins; D016212:Transforming Growth Factor beta