title: Improving classification performance with discretization on biomedical datasets.
abstract: Discretization acts as a variable selection method in addition to transforming the continuous values of the variable to discrete ones. Machine learning algorithms such as Support Vector Machines and Random Forests have been used for classification in high-dimensional genomic and proteomic data due to their robustness to the dimensionality of the data. We show that discretization can help improve significantly the classification performance of these algorithms as well as algorithms like Naïve Bayes that are sensitive to the dimensionality of the data.
authors.affiliation: Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Lustgarten
authors.forename: Vanathi
authors.initials: V
authors.lastname: Gopalakrishnan
authors.forename: Himanshu
authors.initials: H
authors.lastname: Grover
authors.forename: Shyam
authors.initials: S
authors.lastname: Visweswaran
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003628:Database Management Systems; D016208:Databases, Factual; D003661:Decision Support Techniques; D010363:Pattern Recognition, Automated / Q000379:methods*