Does uric acid provide information about maternal condition and fetal outcome in pregnant women with hypertension?
OBJECTIVE
To evaluate associations between maternal serum uric acid (UA) levels, maternal status, and fetal outcome.


METHODS
Maternal UA, urinary protein-creatinine ratio (P/C), blood pressure (BP), gestational age at delivery, and birth weight were evaluated in hypertensive pregnant women (n = 58). These were divided into two groups: high UA (> or =357 micromol/L) or normal UA (<357 micromol/L).


RESULTS
Maternal diastolic BP and P/C ratio were higher in pregnant women with elevated UA levels. Systolic BP, gestational age and birth weight were not significantly different.


CONCLUSIONS
UA equal or above 357 micromol/L in pregnant hypertensive women was associated with proteinuria and diastolic BP, but not with fetal outcome.
Paula
Letícia Germany
LG
Programa de Pós-graduação em Clínica Médica e Ciências da Saúde (Nefrologia), Faculdade de Medicina/Hospital São Lucas, Pontificia Universidade Católica do Rio Grande do Sul., Porto Alegre, RS, Brazil. leticiagpaula@terra.com.br
da Costa
Bartira Ercília Pinheiro
BE
Poli-de-Figueiredo
Carlos Eduardo
CE
Antonello
Ivan Carlos Ferreira
IC
D000328:Adult; D001724:Birth Weight; D001794:Blood Pressure; D003404:Creatinine / Q000652:urine; D005260:Female; D005865:Gestational Age; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood* / Q000503:physiopathology / Q000652:urine; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D047928:Premature Birth / Q000097:blood / Q000652:urine; D011507:Proteinuria / Q000652:urine*; D014527:Uric Acid / Q000097:blood*; D055815:Young Adult
D014527:Uric Acid; D003404:Creatinine