Chronic pericardial constriction induced severe ischemic hepatitis manifesting as hypoglycemic attack.
Ischemic hepatitis, otherwise known as "shock liver", is characterized by a massive, but transient increase in serum transaminase levels, usually associated with cardiac failure. A patient who did not have a predisposition to hypoglycemia was discovered at home with disturbed consciousness caused by hypoglycemia. She had been diagnosed as having constrictive pericarditis several years earlier and had developed ischemic hepatitis. Though the high serum transaminase levels were rapidly normalized, severe jaundice gradually developed and the patient finally died of multiple organ failure. Hypoglycemia, which is considered secondary to reduced gluconeogenesis in the exhausted liver, is a rare complication of constrictive pericarditis.
Nomura
Tetsuya
T
Department of Cardiovascular Medicine, Nantan General Hospital, Nantan, Japan. t2-ya@za2.so-net.ne.jp
Keira
Natsuya
N
Urakabe
Yota
Y
Naito
Daisuke
D
Nakayama
Mayuka
M
Kido
Atsumichi
A
Kanemasa
Hidetoshi
H
Matsubara
Hiroaki
H
Tatsumi
Tetsuya
T
D002908:Chronic Disease; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006505:Hepatitis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis / Q000209:etiology*; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology*; D007565:Jaundice / Q000175:diagnosis / Q000209:etiology; D008099:Liver / Q000098:blood supply*; D008875:Middle Aged; D010494:Pericarditis, Constrictive / Q000150:complications*