title: [Does iv paracetamol have preemptive analgesic effect on lumber disc surgeries?].
abstract: In this study, postoperative analgesic effects of intravenous paracetamol administration in lumbar discectomy patients were evaluated. After the approval of ethic committee, 90 patients undergoing lumbar disc hernia operation randomly divided into 3 groups. After standart general anesthesia, patients in group I received 1 gr i.v. paracetamol infusion 15 minutes before the induction, patients in group II received i.v. Paracetamol infusion started 15 minutes before the end of surgery. i.v morphine via PCA is used for postoperative analgesia maintenance and patients pain scores were assessed with VAS at 0., 1., 2., 3., 6., 12. and 24. hours. First analgesic requirement time, total morphine consumption and side effects were recorded. In group I and II, VAS scores, 24 h morphine consumption and first morphine requirement times were significantly different comparing to group III. As a result, we think that in lumbar discectomy cases preoperative administration of 1 gr paracetamol has no preemptive analgesic effect.
authors.affiliation: Min.of Health Kars Maternity Hospital Dep.of Anesthesia, Kars, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Toygar
authors.forename: Taylan
authors.initials: T
authors.lastname: Akkaya
authors.forename: Derya
authors.initials: D
authors.lastname: Ozkan
authors.forename: Ozgür
authors.initials: O
authors.lastname: Ozel
authors.forename: Ebru
authors.initials: E
authors.lastname: Uslu
authors.forename: Haluk
authors.initials: H
authors.lastname: Gümüş
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000627:therapeutic use*; D000698:Analgesia / Q000379:methods*; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D017586:Diskectomy / Q000009:adverse effects; D006801:Humans; D007262:Infusions, Intravenous; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D009020:Morphine / Q000008:administration & dosage / Q000627:therapeutic use; D010149:Postoperative Pain / Q000188:drug therapy*; D011184:Postoperative Period
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D009020:Morphine