title: Jupiter scleral lenses in the management of chronic graft versus host disease.
abstract: OBJECTIVE
  To describe the use of the Jupiter scleral contact lens (Medlens Innovations, Front Royal, VA or Essilor Contact Lens, Inc., Dallas, TX) in the management of ocular manifestations of chronic graft versus host disease (cGVHD).
  
  
  METHODS
  This study is a retrospective case series. Five consecutive patients with severe keratoconjunctivitis sicca (KCS) associated with cGVHD that could not be adequately managed with conventional therapy were evaluated for scleral contact lens wear between January and December 2007. All patients were evaluated with lenses from the standard 18.2 mm Jupiter B diagnostic fitting set. If lenses of standard design failed to provide adequate fit, custom lenses were designed. Three outcome measures were evaluated: the patient's ability to tolerate and successfully handle the lenses, improvement in symptoms of KCS, and improvement in visual acuity.
  
  
  RESULTS
  All 5 patients (10 eyes) were successfully fit with Jupiter scleral lenses. Six eyes of 3 patients were successfully fit with lenses of standard design. Standard parameters were altered to achieve adequate fit in 4 eyes of 2 patients. All patients reported subjective improvements in comfort with Jupiter scleral lenses, and best-corrected vision improved in 7 of the 10 eyes fit within the first several months of contact lens wear. The remaining 3 eyes maintained the visual acuity measured before scleral lens wear (20/20 in 2 eyes, 20/40 in 1 eye). Duration of follow-up ranged from 4 to 14 months.
  
  
  CONCLUSIONS
  Jupiter scleral lenses can relieve symptoms of KCS and may improve vision in patients with cGVHD.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA. schornack.muriel@mayo.edu
authors.forename: Muriel M
authors.initials: MM
authors.lastname: Schornack
authors.forename: Keith H
authors.initials: KH
authors.lastname: Baratz
authors.forename: Sanjay V
authors.initials: SV
authors.lastname: Patel
authors.forename: Leo J
authors.initials: LJ
authors.lastname: Maguire
mesh_terms: D000328:Adult; D003261:Contact Lenses; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000150:complications*; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017755:Prosthesis Fitting; D012189:Retrospective Studies; D012590:Sclera; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity