title: Antibacterial activity of Thai medicinal plants against methicillin-resistant Staphylococcus aureus.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen which causes severe morbidity and mortality worldwide. Seventeen Thai medicinal plants were investigated for their activity against MRSA. Garcinia mangostana was identified as the most potent plant, and its activity was traced to the prenylated xanthone, alpha-mangostin (MIC and MBC values of 1.95 and 3.91 microg/ml, respectively).
authors.affiliation: Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. scmtd@mahidol.ac.th
authors.forename: Mullika Traidej
authors.initials: MT
authors.lastname: Chomnawang
authors.forename: Suvimol
authors.initials: S
authors.lastname: Surassmo
authors.forename: Karn
authors.initials: K
authors.lastname: Wongsariya
authors.forename: Nuntavan
authors.initials: N
authors.lastname: Bunyapraphatsara
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D029762:Garcinia mangostana; D019684:Magnoliopsida; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D013785:Thailand; D044004:Xanthones / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D044004:Xanthones; C021053:mangostin