title: [Study the inhibitory effects of three oral actinomyces on growth of oral Candida albicans in vitro].
abstract: OBJECTIVE
  The aim of this study was to investigate whether the three species of oral Actinomyces have inhibitory effects on the growth of oral Candida albicans in vitro.
  
  
  METHODS
  Straight o'clock method was used to observe the bacteriostasis circle. Reverse o'clock and mixed culture method were used to study the quantitative changes of Candida albicans colony respectively.
  
  
  RESULTS
  (1) None of the groups had been viewed the bacteriostasis circle. (2) Compared with control groups, there was a significant decrease of Candida albicans colony on Actinomyces viscosus TPY soft agar (P < 0.05). Actinomyces naeslundii and Actinomyces odontolyticus TPY soft agar were both devoid of obvious Candida albicans colony (P < 0.01). The former group (Actinomyces viscosus) and the two latter groups (Actinomyces naeslundii and Actinomyces odontolyticus) showed a striking contrast (P < 0.01). (3) Compared with control groups, a decrease of Candida albicans showed up in the mixed culture, and the difference was significant (P < 0.05). The discrepancies among the three experimental groups were of no statistical value (P > 0.05).
  
  
  CONCLUSIONS
  Oral Actinomyces viscosus, Actinomyces naeslundii and Actinomyces odontolyticus could inhibit the growth of Candida albicans in vitro. However, which of them contributed more to the inhibitory effects was still not affirmed.
authors.affiliation: State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
authors.forename: Duo
authors.initials: D
authors.lastname: Li
authors.forename: Xiao-rong
authors.initials: XR
authors.lastname: Xiao
authors.forename: Zhu
authors.initials: Z
authors.lastname: Zhu
authors.forename: Qian
authors.initials: Q
authors.lastname: Ren
authors.forename: Tao
authors.initials: T
authors.lastname: Hu
authors.forename: Qi-mei
authors.initials: QM
authors.lastname: Gong
authors.forename: Hong-mei
authors.initials: HM
authors.lastname: Zhou
mesh_terms: D000190:Actinomyces; D016924:Actinomyces viscosus; D002176:Candida albicans; D066298:In Vitro Techniques