title: Synthesis and enantiomeric resolution of (+/-)-pinocembrin.
abstract: A convenient method for the synthesis and enantiomeric resolution of ( +/- )-pinocembrin has been developed. This route involves the hydrogenation of 5,7-dihydroxyflavone, the derivatization of racemic pinocembrin with chiral amine, and the separation of the diastereoisomers due to their different physical properties.
authors.affiliation: Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Yuan
authors.forename: Qing-Yun
authors.initials: QY
authors.lastname: Yang
authors.forename: Yuan-Feng
authors.initials: YF
authors.lastname: Tong
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Yan
authors.initials: Y
authors.lastname: Qi
authors.forename: Ya-Bo
authors.initials: YB
authors.lastname: Duan
authors.forename: Song
authors.initials: S
authors.lastname: Wu
mesh_terms: D044950:Flavanones / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D044950:Flavanones; C016063:pinocembrin