title: Ruptured cerebral fusiform aneurysm with mucopolysaccharide deposits in the tunica media in a patient with Marfan syndrome.
abstract: Although aortic or cardiac complications are common in patients with Marfan syndrome, the presence of an intracranial aneurysm is comparatively rare. In this study, the authors report on their experience with resection of a ruptured fusiform aneurysm of the posterior cerebral artery in a 30-year-old woman with Marfan syndrome. Microscopic examination of the resected tissue showed many Alcian blue-staining deposits, consistent with the presence of mucopolysaccharide in the tunica media and focal fragmentation of the internal elastic lamina.
authors.affiliation: Departments of Neurosurgery, Iwate Medical University, Uchimaru, Morioka, Japan. yokubo@iwate-ed.ac.jp
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Kubo
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Ogasawara
authors.forename: Akira
authors.initials: A
authors.lastname: Kurose
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Kakino
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Tomitsuka
authors.forename: Akira
authors.initials: A
authors.lastname: Ogawa
mesh_terms: D000328:Adult; D017542:Aneurysm, Ruptured / Q000378:metabolism* / Q000601:surgery; D005260:Female; D006025:Glycosaminoglycans / Q000378:metabolism*; D006651:Histocytochemistry; D006801:Humans; D002532:Intracranial Aneurysm / Q000378:metabolism* / Q000601:surgery; D008382:Marfan Syndrome / Q000150:complications*; D020769:Posterior Cerebral Artery; D017540:Tunica Media / Q000378:metabolism*
chemical_list: D006025:Glycosaminoglycans