Haplotype-specific sequencing reveals a novel HLA-B*37 allele, B*3714.
We report on a novel human leukocyte antigen (HLA)-B allele, HLA-B*3714. This allele differs from HLA-B*3711 by two nucleic acid substitutions at positions 317 and 319 in exon 2, both resulting in amino acid exchanges. The first one leads to the exchange from arginine to leucine at position 82, and the latter one from glycine to arginine at position 83.
Emmerich
F
F
Center for Tumor Medicine, Institute for Transfusion Medicine, Charité University Medicine, Berlin, Germany. florian.emmerich@charite.de
Schönemann
C
C
Diederich
G
G
Salama
A
A
D000328:Adult; D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D005260:Female; D015235:HLA-B Antigens / Q000235:genetics*; D059912:HLA-B37 Antigen; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data
D015235:HLA-B Antigens; C538920:HLA-B*37:14 antigen; D059912:HLA-B37 Antigen