title: Epigenetics in the nervous system.
abstract: It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.
authors.affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01604, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
authors.forename: Brett
authors.initials: B
authors.lastname: Langley
authors.forename: Farah D
authors.initials: FD
authors.lastname: Lubin
authors.forename: William
authors.initials: W
authors.lastname: Renthal
authors.forename: Marcelo A
authors.initials: MA
authors.lastname: Wood
authors.forename: Dag H
authors.initials: DH
authors.lastname: Yasui
authors.forename: Arvind
authors.initials: A
authors.lastname: Kumar
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Nestler
authors.forename: Schahram
authors.initials: S
authors.lastname: Akbarian
authors.forename: Andrea C
authors.initials: AC
authors.lastname: Beckel-Mitchener
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000235:genetics* / Q000378:metabolism* / Q000503:physiopathology; D002843:Chromatin / Q000235:genetics / Q000378:metabolism; D019175:DNA Methylation / Q000235:genetics; D044127:Epigenesis, Genetic / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D056572:Histone Deacetylase Inhibitors; D006655:Histone Deacetylases / Q000378:metabolism; D006657:Histones / Q000235:genetics / Q000378:metabolism; D006801:Humans; D009420:Nervous System / Q000378:metabolism*
chemical_list: D002843:Chromatin; D056572:Histone Deacetylase Inhibitors; D006657:Histones; D006655:Histone Deacetylases