title: Primary sclerosing cholangitis.
abstract: Primary sclerosing cholangitis (PSC) is a generally progressive, sometimes fatal chronic hepatobiliary disorder for which no effective medical therapy now exists. This article describes the epidemiology of this disease, along with diagnosis and treatment options. Future research directions concerning PSC also are discussed.
authors.affiliation: Lahey Clinic Medical Center, Hepatobiliary and Liver Transplantation, 41 Mall Road, 4 West, Burlington, MA 01805, USA. fredric_d_gordon@lahey.org
authors.forename: Fredric D
authors.initials: FD
authors.lastname: Gordon
mesh_terms: D015209:Cholangitis, Sclerosing / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D003937:Diagnosis, Differential; D003938:Diagnostic Techniques, Digestive System; D013505:Digestive System Surgical Procedures / Q000379:methods*; D014943:Global Health; D006801:Humans; D009017:Morbidity / Q000639:trends