Concurrent chemoradiotherapy for primary cervical spinal cord germinoma.
We report a rare case of primary intramedullary germinoma in the cervical spine of a 39-year-old woman without evidence of intracranial or disseminated disease. The germinoma was treated by a biopsy and follow-up concurrent chemoradiotherapy. This is the only reported case of primary spinal cord germinoma for which concurrent chemoradiotherapy was given. Furthermore, this is only the second reported case of histologically documented primary intramedullary cervical spinal cord germinoma. The patient was disease-free and there was near-complete resolution of the pre-operative neurological deficits at the 20-month follow-up examination.
Yang
Ka-Yen
KY
Department of Neurosurgery, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung 833, Taiwan.
Li
Shau-Hsuan
SH
Lin
Jui-Wei
JW
Su
Thung-Ming
TM
Ho
Jih-Tsun
JT
Chen
Wu-Fu
WF
D000328:Adult; D004358:Drug Therapy / Q000379:methods*; D005260:Female; D018237:Germinoma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016634:Radiosurgery / Q000379:methods*; D013120:Spinal Cord Neoplasms / Q000473:pathology / Q000628:therapy*