title: Acute renal failure due to visceral leishmaniasis by Leishmania infantum successfully treated with a single high dose of liposomal amphotericin B.
abstract: We report a visceral leishmaniasis case in an immunocompetent immigrant with acute renal failure. Parasites were demonstrated in bone marrow, peripheral blood, and kidney samples. A collapsing focal segmental glomerulosclerosis was documented, which was successfully treated with a single infusion of 10 mg/kg liposomal amphotericin B.
authors.affiliation: Clinic of Infectious Diseases, Department of Clinical and Morphological Research, University of Udine, Udine, Italy. beltrame.anna@aoud.sanita.ivg.it
authors.forename: Anna
authors.initials: A
authors.lastname: Beltrame
authors.forename: Alessandra
authors.initials: A
authors.lastname: Arzese
authors.forename: Alessandro
authors.initials: A
authors.lastname: Camporese
authors.forename: Giada
authors.initials: G
authors.lastname: Rorato
authors.forename: Massimo
authors.initials: M
authors.lastname: Crapis
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Tarabini-Castellani
authors.forename: Giuliano
authors.initials: G
authors.lastname: Boscutti
authors.forename: Stefano
authors.initials: S
authors.lastname: Pizzolitto
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Calianno
authors.forename: Alberto
authors.initials: A
authors.lastname: Matteelli
authors.forename: Trentina
authors.initials: T
authors.lastname: Di Muccio
authors.forename: Marina
authors.initials: M
authors.lastname: Gramiccia
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Viale
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000382:microbiology*; D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage*; D000810:Angola; D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005921:Glomerulonephritis / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D007558:Italy; D018314:Leishmania infantum / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D014195:Travel; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B