title: Giant breast tumors: surgical management of phyllodes tumors, potential for reconstructive surgery and a review of literature.
abstract: BACKGROUND
  Phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. While the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors greater than ten centimeters in diameter - the giant phyllodes tumor.
  
  
  METHODS
  We report two cases of giant breast tumors and discuss the techniques utilized for pre-operative diagnosis, tumor removal, and breast reconstruction. A review of the literature on the surgical management of phyllodes tumors was performed.
  
  
  CONCLUSIONS
  Management of the giant phyllodes tumor presents the surgeon with unique challenges. The majority of these tumors can be managed by simple mastectomy. Axillary lymph node metastasis is rare, and dissection should be limited to patients with pathologic evidence of tumor in the lymph nodes.
authors.affiliation: Ohio State College of Medicine, Columbus, Ohio, USA. Margaret.Liang@osumc.edu
authors.forename: Margaret I
authors.initials: MI
authors.lastname: Liang
authors.forename: Bhuvaneswari
authors.initials: B
authors.lastname: Ramaswamy
authors.forename: Cynthia C
authors.initials: CC
authors.lastname: Patterson
authors.forename: Michael T
authors.initials: MT
authors.lastname: McKelvey
authors.forename: Gayle
authors.initials: G
authors.lastname: Gordillo
authors.forename: Gerard J
authors.initials: GJ
authors.lastname: Nuovo
authors.forename: William E
authors.initials: WE
authors.lastname: Carson
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D016462:Mammaplasty; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome