A novel allele, HLA-A*0128, identified by sequence-based typing in a Chinese individual.
In this report, we describe the identification of a novel allele HLA-A*0128, which was found in a registered donor from China Marrow Donor Program. The A*0128 allele differs from the A*0113 by one nucleotide substitutions in exon 2 at position 282 (G-->C). The mutation results in a codon change: at codon 70 where a glutamine acid is substituted by a histidine acid.
Shuang
C
C
HLA Laboratory, Beijing Red Cross Blood Center, Beijing, China. chris_cui@sohu.com
Shan
X
X
Zhang
Z
Z
D000483:Alleles; D001483:Base Sequence; D002681:China; D005091:Exons / Q000235:genetics; D015234:HLA-A Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics
D015234:HLA-A Antigens