title: Small orbitofrontal traumatic lesions detected by high resolution MRI in a patient with major behavioural changes.
abstract: We report a case of a male patient who showed personality changes and marked social problems after a traumatic brain injury. Although suspected to have lesions in the orbitofrontal cortex because of the typical characteristics of his behavioural change, lesions were not apparent using conventional imaging techniques. However, investigation using high-resolution MRI revealed lesions in the orbitofrontal cortex. Our case suggests that standard MRI scanning techniques may have only limited power. Hence, we stress the important role played by qualitative assessments of emotion, personality, and social behaviour in evaluating sequelae of traumatic orbitofrontal injuries.
authors.affiliation: Human Brain Research Centre, Kyoto, Japan. cnamiki@kuhp.kyoto-u.ac.jp
authors.forename: Chihiro
authors.initials: C
authors.lastname: Namiki
authors.forename: Makiko
authors.initials: M
authors.lastname: Yamada
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Yoshida
authors.forename: Takashi
authors.initials: T
authors.lastname: Hanakawa
authors.forename: Hidenao
authors.initials: H
authors.lastname: Fukuyama
authors.forename: Toshiya
authors.initials: T
authors.lastname: Murai
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000150:complications / Q000473:pathology; D004644:Emotions; D005625:Frontal Lobe / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010554:Personality Disorders / Q000209:etiology / Q000473:pathology; D012920:Social Behavior Disorders / Q000209:etiology*