Localization of metastases from malignant pheochromocytoma in patients undergoing 131I-MIBG therapy with manually fused 123I-MIBG SPECT and CT images.
(131)I-metaiodobenzylguanidine (MIBG) has been used as a therapeutic agent for pheochromocytoma. Tumor localization and precise staging are essential for therapy with high-dose (131)I-MIBG. The sites and extent of (123)I-MIBG uptake are usually estimated to predict the effectiveness of therapy before administration. However, conventional scintigraphic images provide insufficient anatomic information. Therefore, we tried to manually superimpose (123)I-MIBG SPECT and CT images using free software.
Kizu
Hiroto
H
Department of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan. kizu@cf6.so-net.ne.jp
Takayama
Teruhiko
T
Tsushima
Hiroyuki
H
Noguchi
Atsushi
A
Nakajima
Kenichi
K
Onoguchi
Masahisa
M
Kinuya
Seigo
S
D019797:3-Iodobenzylguanidine / Q000627:therapeutic use*; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D005240:Feasibility Studies; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000556:secondary*; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine