title: Performance of in-hospital mortality prediction models for acute hospitalization: hospital standardized mortality ratio in Japan.
abstract: OBJECTIVE
  In-hospital mortality is an important performance measure for quality improvement, although it requires proper risk adjustment. We set out to develop in-hospital mortality prediction models for acute hospitalization using a nation-wide electronic administrative record system in Japan.
  
  
  METHODS
  Administrative records of 224,207 patients (patients discharged from 82 hospitals in Japan between July 1, 2002 and October 31, 2002) were randomly split into preliminary (179,156 records) and test (45,051 records) groups. Study variables included Major Diagnostic Category, age, gender, ambulance use, admission status, length of hospital stay, comorbidity, and in-hospital mortality. ICD-10 codes were converted to calculate comorbidity scores based on Quan's methodology. Multivariate logistic regression analysis was then performed using in-hospital mortality as a dependent variable. C-indexes were calculated across risk groups in order to evaluate model performances.
  
  
  RESULTS
  In-hospital mortality rates were 2.68% and 2.76% for the preliminary and test datasets, respectively. C-index values were 0.869 for the model that excluded length of stay and 0.841 for the model that included length of stay.
  
  
  CONCLUSIONS
  Risk models developed in this study included a set of variables easily accessible from administrative data, and still successfully exhibited a high degree of prediction accuracy. These models can be used to estimate in-hospital mortality rates of various diagnoses and procedures.
authors.affiliation: Department of Healthcare Quality Assessment, Graduate School of Medicine, University of Tokyo, Japan. h-m@umin.ac.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Miyata
authors.forename: Hideki
authors.initials: H
authors.lastname: Hashimoto
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Horiguchi
authors.forename: Shinya
authors.initials: S
authors.lastname: Matsuda
authors.forename: Noboru
authors.initials: N
authors.lastname: Motomura
authors.forename: Shinichi
authors.initials: S
authors.lastname: Takamoto
mesh_terms: D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008499:Medical Records / Q000706:statistics & numerical data; D008962:Models, Theoretical; D011237:Predictive Value of Tests; D020379:Risk Adjustment / Q000379:methods*