title: Synthesis and structure revision of nakiterpiosin.
abstract: This manuscript describes a convergent synthesis and the revision of the relative stereochemistry of nakiterpiosin, a marine C-nor-D-homosteroid. Our synthesis features a late-stage carbonylative Stille cross-coupling reaction and a photo-Nazarov cyclization reaction that deliver the complete nakiterpiosin skeleton efficiently.
authors.affiliation: Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA.
authors.forename: Shuanhu
authors.initials: S
authors.lastname: Gao
authors.forename: Qiaoling
authors.initials: Q
authors.lastname: Wang
authors.forename: Chuo
authors.initials: C
authors.lastname: Chen
mesh_terms: D006718:Homosteroids / Q000138:chemical synthesis* / Q000737:chemistry; D008387:Marine Toxins / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D006718:Homosteroids; D008387:Marine Toxins; C539406:nakiterpiosin