title: True hematogenous metastases of melanoma on contralateral skin graft donor site: a case report.
abstract: The incidence of cutaneous melanoma, the most lethal form of skin cancer, is increasing all over the world. Malignant melanoma spreads through hematogenous, lymphagenous path, or by iatrogenic implantations. In this report, we present an unusual case in which a patient experienced the development of melanoma within the split-thickness skin graft donor site on the contralateral lower extremity. Metastases of malignant melanoma occurred in the donor site of the graft, 8 weeks after primary tumor excision, ipsilateral axillary dissection, and reconstruction with a split-thickness skin graft harvested from the contralateral upper thigh. As eight melanoma nodules were seen in donor area, we strongly suspect that spreading of melanoma occurred via a true hematogenous pathway in this case.
authors.affiliation: Department of Plastic, Reconstructive and Aesthetic Surgery, Medical Faculty of Trakya University, Edirne, Turkey. drebenlier@hotmail.com
authors.forename: Benlier
authors.initials: B
authors.lastname: Erol
authors.forename: Usta
authors.initials: U
authors.lastname: Ufuk
authors.forename: Top
authors.initials: T
authors.lastname: Husamettin
authors.forename: Unal
authors.initials: U
authors.lastname: Yasin
authors.forename: Cayci
authors.initials: C
authors.lastname: Aslihan
authors.forename: Kir
authors.initials: K
authors.lastname: Koray
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis; D006801:Humans; D008207:Lymphatic Metastasis; D058965:MART-1 Antigen; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000209:etiology* / Q000556:secondary; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D016038:Skin Transplantation / Q000009:adverse effects*
chemical_list: D000951:Antigens, Neoplasm; D058965:MART-1 Antigen; C548667:MLANA protein, human; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins