title: Idiopathic inflammatory myopathies.
abstract: The idiopathic inflammatory myopathies are a group of systemic autoimmune syndromes characterized by striated muscle inflammation. Here, we discuss the clinical features of this group of conditions and review the recent developments in the understanding of the pathogenesis and immunogenetics of the idiopathic inflammatory myopathies. The role of myositis-specific autoantibodies and their clinical significance and an overview of management are also provided.
authors.affiliation: Rheumatology Department, Royal Adelaide Hospital, University of Adelaide, South Australia, Australia. vidya.limaye@health.sa.gov.au
authors.forename: V S
authors.initials: VS
authors.lastname: Limaye
authors.forename: P
authors.initials: P
authors.lastname: Blumbergs
authors.forename: P J
authors.initials: PJ
authors.lastname: Roberts-Thomson
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D009220:Myositis / Q000188:drug therapy / Q000235:genetics / Q000276:immunology / Q000473:pathology; D011379:Prognosis
chemical_list: D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D007166:Immunosuppressive Agents