title: Spectral-domain optical coherence tomography images of inner/outer segment junctions and macular hole surgery outcomes.
abstract: BACKGROUND
  To evaluate the ability of spectral-domain optical coherence tomography (SD-OCT) images of the inner/outer segment (IS/OS) junction to predict macular hole surgery outcomes.
  
  
  METHODS
  Fifty-four eyes in 53 patients with idiopathic macular holes were studied. Postoperative visual acuity and SD-OCT images of the fovea were examined before and 12 months after surgery. The total area and the maximum length of the IS/OS junction defect were measured.
  
  
  RESULTS
  The macular holes were successfully closed in all the eyes included in this series. The mean log MAR visual acuity improved significantly from 0.67 +/- 0.25 preoperatively to 0.16 +/- 0.22 postoperatively (p < 0.001). The mean total area and maximum length of the IS/OS junction defect at 12 months after surgery were 10,185 +/- 1,537 microm(2) and 100.5 +/- 10.4 microm respectively; these values were significantly negatively correlated with the postoperative visual acuity.
  
  
  CONCLUSIONS
  SD-OCT is useful for quantitatively measuring IS/OS junction defects. The postoperative IS/OS junction may play an important role in visual recovery after macular hole surgery.
authors.affiliation: Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan. maicoo@urahp.yokohama-cu.ac.jp
authors.forename: Maiko
authors.initials: M
authors.lastname: Inoue
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Akira
authors.initials: A
authors.lastname: Arakawa
authors.forename: Shimpei
authors.initials: S
authors.lastname: Sato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Kadonosono
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000175:diagnosis* / Q000601:surgery*; D055211:Retinal Photoreceptor Cell Inner Segment / Q000473:pathology*; D055214:Retinal Photoreceptor Cell Outer Segment / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology