title: Developing a distributed research network to conduct population-based studies and safety surveillance.
abstract: The Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) centers at the HMO Research Network Center for Education and Research on Therapeutics (HMORN CERT) and the University of Pennsylvania are developing a design for a scalable distributed research network (DRN) to support a wide array of purposes related to therapeutics, including comparative effectiveness, safety, and utilization, as well as quality of care research. The project will implement a system prototype, conduct a proof of principle research project on hypertension therapy, and make recommendations for future expansion of the network.
authors.affiliation: University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
authors.forename: John H
authors.initials: JH
authors.lastname: Holmes
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Brown
authors.forename: Sean
authors.initials: S
authors.lastname: Hennessy
authors.forename: Kimberly
authors.initials: K
authors.lastname: Lane
authors.forename: Robert D
authors.initials: RD
authors.lastname: Langer
authors.forename: Ross
authors.initials: R
authors.lastname: Lazarus
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: O'Connor
authors.forename: Brian L
authors.initials: BL
authors.lastname: Strom
authors.forename: Richard
authors.initials: R
authors.lastname: Platt
mesh_terms: D003195:Computer Communication Networks / Q000458:organization & administration*; D003299:Cooperative Behavior; D010414:Pennsylvania; D011159:Population Surveillance / Q000379:methods*; D012106:Research / Q000458:organization & administration*; D012107:Research Design; D017751:Safety Management / Q000458:organization & administration*