Total phenolics level, antioxidant activities and cytotoxicity of young sprouts of some traditional Korean salad plants.
The aim of this investigation was to study the antioxidant and anticancer activities of young sprouts of some traditional Korean salad plants. Total phenolics, antioxidant and anticancer activities of the methanol extracts from young sprouts of 11 salad plants were determined. The highest amount of phenolics was found in methanol extracts of Euonymus alatus (235.7 mg kg(-1)), followed by Hypericum ascyron (197.1 mg kg(-1)), Zanthoxylum piperitum (194.1 mg kg(-1)) and Zanthoxylum schinifolium (142.5 mg kg(-1)). Methanol extracts of E. alatus, H. ascyron, and Z. piperitum at 63 mg kg(-1) exhibited the highest dose-depend DPPH radical scavenging activity by 91.2, 91.2 and 83.9%, respectively. According to the MTT results, the methanol extracts from Stellaria aquatica, Eleutherococcus sessilifolrus and Z. schinifolium showed the highest anticancer activities against Calu-6 (IC50<25.0 microg ml(-1)) and from S. aquatica-the highest anticancer activities against SNU-601 (153.3 microg ml(-1)), following by E. sessilifolrus (196.7 microg ml(-1)) and Amaranthus mangostanus (303.1 microg ml(-1)). Total phenolics were highly correlated with the DPPH, suggesting that they contribute to the antioxidant properties of the studied plants.


CONCLUSIONS
young sprouts of Korean salad possess antioxidant and anticancer properties and could be used as a supplement to proper drugs.
Chon
Sang-Uk
SU
EFARINET Co. Ltd., BI Center, Chosun University, Gwangju, 501-759, South Korea.
Heo
Buk-Gu
BG
Park
Yong-Seo
YS
Kim
Dong-Kwan
DK
Gorinstein
Shela
S
D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis* / Q000494:pharmacology; D000975:Antioxidants / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D028001:Eleutherococcus / Q000737:chemistry; D029756:Euonymus / Q000737:chemistry; D016166:Free Radical Scavengers; D020902:Hypericum / Q000737:chemistry; D007723:Korea; D010636:Phenols / Q000032:analysis* / Q000494:pharmacology; D010936:Plant Extracts / Q000032:analysis* / Q000494:pharmacology; D013045:Species Specificity; D029752:Stellaria / Q000737:chemistry; D032106:Zanthoxylum / Q000737:chemistry
D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D016166:Free Radical Scavengers; D010636:Phenols; D010936:Plant Extracts