title: Complications of arteriovenous hemodialysis access: recognition and management.
abstract: English language citations reporting complications of arteriovenous access for hemodialysis are critically reviewed and discussed. Venous hypertension, arterial steal syndrome, and high-output cardiac failure occur as a result of hemodynamic alterations potentiated by access flow. Uremic and diabetic neuropathies are common but may obfuscate recognition of potentially correctable problems such as compression or ischemic neuropathy. Mechanical complications include pseudoaneurysm, which may develop from a puncture hematoma, degeneration of the wall, or infection. Dysfunctional hemostasis, hemorrhage, noninfectious fluid collections, and access-related infections are, in part, manifestations of the adverse effects of uremia on the function of circulating hematologic elements. Impaired erythropoiesis is successfully managed with hormonal stimulation; perhaps, similar therapies can be devised to reverse platelet and leukocyte dysfunction and reduce bleeding and infectious complications.
authors.affiliation: Department of Surgery, Section of Vascular Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, USA. padbergjr@aol.com
authors.forename: Frank T
authors.initials: FT
authors.lastname: Padberg
authors.forename: Keith D
authors.initials: KD
authors.lastname: Calligaro
authors.forename: Anton N
authors.initials: AN
authors.lastname: Sidawy
mesh_terms: D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects*; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis* / Q000628:therapy*; D006435:Renal Dialysis / Q000379:methods*; D016896:Treatment Outcome