title: Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch.
abstract: DNA-tagged liposomes made of DOPC specifically bind to a fluorescently labelled complementary ss-DNA with virtually no influence from the lipid bilayer despite the absence of a linker; depending on an external stimulus, either physical (temperature) or chemical (competitive complementary ON sequences), the liposomes switch between an on and off fluorescent state depending on the location of the probe either at the surface or in the bulk.
authors.affiliation: Université de Bordeaux, 33076 Bordeaux Cedex, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gissot
authors.forename: Carmelo
authors.initials: C
authors.lastname: Di Primo
authors.forename: Isabelle
authors.initials: I
authors.lastname: Bestel
authors.forename: Gregory
authors.initials: G
authors.lastname: Giannone
authors.forename: Hubert
authors.initials: H
authors.lastname: Chapuis
authors.forename: Philippe
authors.initials: P
authors.lastname: Barthélémy
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000737:chemistry; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D008051:Lipid Bilayers; D008081:Liposomes; D009841:Oligonucleotides; D010713:Phosphatidylcholines; D013501:Surface-Active Agents; C017251:1,2-oleoylphosphatidylcholine