Improving aminoglycoside dosing through computerized clinical decision support and pharmacy therapeutic monitoring systems.
Dosing errors and inadequate laboratory monitoring of aminoglycosides may lead to significant adverse drug events. Correctly prescribing aminoglycosides requires familiarity with multiple mathematically complicated dosing and laboratory monitoring protocols. We developed a clinical decision support system for ordering aminoglycosides which is integrated into a computerized provider order entry system. To complement the ordering tool, we implemented a real-time tracking application to allow the pharmacist-staffed therapeutic drug monitoring service to follow patients prescribed aminoglycosides.
Phillips
Ira E
IE
Vanderbilt University, Nashville, Tennessee, USA.
Nelsen
Cori
C
Peterson
Josh
J
Sullivan
Thomas M
TM
Waitman
Lemuel R
LR
D000617:Aminoglycosides / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001424:Bacterial Infections / Q000188:drug therapy*; D020000:Decision Support Systems, Clinical; D016903:Drug Monitoring / Q000379:methods*; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D006801:Humans; D050316:Medical Order Entry Systems; D008510:Medication Systems, Hospital; D013714:Tennessee
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents