title: [Considerable comorbidity in overweight adults: results from the Utrecht Health Project].
abstract: OBJECTIVE
  To determine the association between overweight, physical and mental health conditions and health-related quality of life in an adult community population upon entering a new primary care practice.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Baseline data from 4825 participants (mean age: 39 years; 55% women) in the Utrecht Health Project; a dynamic primary care population study with a response rate of over 50%, were used to determine and compare the prevalence of diagnosed medical conditions, complaints and quality of life between individuals of normal weight (BMI 18.5-< 25 kg/m2) and those who were overweight (BMI 25-< 30 kg/m2) or obese (BMI > or = 30 kg/m2). Normal weight was used as the reference category.
  
  
  RESULTS
  Overweight individuals were approximately twice as likely to have cardiovascular risk factors and had a 20-60% increased risk of back pain, arthrosis, migraine, dyspepsia and respiratory symptoms than those of normal weight. Obese individuals were almost twice to four times more likely to have these conditions and were additionally at increased risk of obstructive pulmonary disease, cardiovascular disease and arthritis (range of odds ratios (ORs): 1.9-3.3). Somatization and reduced physical well-being were more common among both overweight (ORs: 1.2-1.5) and obese (ORs: 1.7-3.7) individuals, whereas only obese individuals demonstrated a 30-50% increased risk of mental health conditions and reduced mental well-being.
  
  
  CONCLUSIONS
  Overweight was associated with a broad range of physical and mental health conditions and a reduced health-related quality of life. Routine measurement of BMI upon entering a primary care practice is relatively simple and may contribute to the identification of individuals at high risk of comorbidity.
authors.affiliation: Afd. Klinische Epidemiologie, Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht. e.a.molenaar@umcutrecht.nl
authors.forename: E A
authors.initials: EA
authors.lastname: Molenaar
authors.forename: M E
authors.initials: ME
authors.lastname: Numans
authors.forename: E J C
authors.initials: EJ
authors.lastname: van Ameijden
authors.forename: D E
authors.initials: DE
authors.lastname: Grobbee
mesh_terms: D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D009426:Netherlands / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology* / Q000401:mortality / Q000523:psychology*; D050177:Overweight / Q000453:epidemiology* / Q000401:mortality / Q000523:psychology*; D011788:Quality of Life; D012307:Risk Factors; D013851:Thinness / Q000453:epidemiology / Q000401:mortality / Q000523:psychology