A protein-supported fluorescent reagent for the highly-sensitive and selective detection of mercury ions in aqueous solution and live cells.
A fluorescent sensor, dansyl-l-aspartic acid (1), coupled with BSA was used to specifically detect Hg2+ in a neutral aqueous solution as well as in live cells; the fluorescence emission spectrum underwent an obvious blue shift with an enhancement in fluorescence intensity, and these effects were evident as color changes in fluorescence imaging pictures.
Ma
Li-Jun
LJ
State Key Lab for Supramolecular Structure and Material, Jilin University, No. 2699, Qianjin Street, Changchun, 130012, China.
Li
Yue
Y
Li
Lei
L
Sun
Jian
J
Tian
Chunjuan
C
Wu
Yuqing
Y
D000818:Animals; D001224:Aspartic Acid / Q000737:chemistry; D002412:Cations / Q000737:chemistry; D002460:Cell Line; D002470:Cell Survival; D009682:Magnetic Resonance Spectroscopy; D008628:Mercury / Q000032:analysis* / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D011506:Proteins / Q000032:analysis* / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012996:Solutions; D013050:Spectrometry, Fluorescence / Q000379:methods*
D002412:Cations; D011506:Proteins; D012996:Solutions; D001224:Aspartic Acid; D008628:Mercury