title: Microfluidics: applications for analytical purposes in chemistry and biochemistry.
abstract: In this review, we present recent advancements and novel developments in fluidic systems for applied analytical purposes in chemistry, biochemistry, and life science in general that employ and reflect the full benefits of microfluidics. A staggering rise in publications related to integrated, all-in-one microfluidic chips capable of separation, reaction, and detection have been observed, all of which realise the principal of micro total analysis systems or lab-on-a-chip. These integrated chips actively adopt the scaling law concepts, utilising the highly developed fabrication techniques. Their aim is to multi-functionalise and fully automate devices believed to assist the future advancements of point-of-care, clinical, and medical diagnostics.
authors.affiliation: Institute for Analytical Sciences, Dortmund, Germany.
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Ohno
authors.forename: Kaoru
authors.initials: K
authors.lastname: Tachikawa
authors.forename: Andreas
authors.initials: A
authors.lastname: Manz
mesh_terms: D001671:Biochemistry / Q000379:methods; D002621:Chemistry / Q000379:methods; D002845:Chromatography / Q000379:methods; D004586:Electrophoresis / Q000379:methods; D006801:Humans; D007118:Immunoassay / Q000379:methods; D046210:Microfluidic Analytical Techniques; D044085:Microfluidics / Q000295:instrumentation / Q000379:methods; D019095:Point-of-Care Systems; D016133:Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods