A new pregnane glycoside from Marsdenia roylei as potential antioxidant and antidyslipidemic agents.
A new pregnane glycoside roylenine (1) was isolated from the CHCl(3)-EtOH (4:1) extract of Marsdenia roylei. Its structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (6) were evaluated for their antioxidant and antidyslipidemic activities.
Sethi
Arun
A
Department of Chemistry, University of Lucknow, Lucknow, India. alkaarunsethi@rediffmail.com
Paswan
Sudha
S
Srivastava
Sanjay
S
Khare
Naveen Kumar
NK
Bhatia
Akriti
A
Kumar
Alok
A
Bhatia
Geetika
G
Khan
Mohammad Mubin
MM
Khanna
Ashok Kumar
AK
Saxena
Jitendra Kumar
JK
D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D001786:Blood Glucose / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology*; D006949:Hyperlipidemias / Q000139:chemically induced / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology; D031101:Marsdenia / Q000737:chemistry*; D015394:Molecular Structure; D011092:Polyethylene Glycols / Q000633:toxicity; D011278:Pregnanes / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D013481:Superoxides / Q000737:chemistry
D000975:Antioxidants; D001786:Blood Glucose; D006027:Glycosides; D007004:Hypoglycemic Agents; D011278:Pregnanes; D013481:Superoxides; D011092:Polyethylene Glycols; C016811:tyloxapol