title: [Clinical features of pulmonary disease caused by Mycobacterium fortuitum].
abstract: We analyzed clinical and microbiological features of six cases involving Mycobacterium fortuitum isolated from sputum or surgical lung specimen. Patients were five men and one woman with an average age of 59. Four cases had a history of pulmonary tuberculosis and three had nontuberculous mycobacterial lung disease. Three out of six cases had underlying chronic obstructive pulmonary disease. Diabetes mellitus was complicated in five cases. All diseases were in the upper lobes of either lung. Clinical symptoms were mainly cough and sputum, while two cases developed pneumothorax. Although all strains showed low sensitivity to standard anti-tuberculous agents, chemotherapy including those drugs or fluoroquinolones and macrolides were successful in all treated cases.
authors.affiliation: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center.
authors.forename: Eri
authors.initials: E
authors.lastname: Hagiwara
authors.forename: Akimasa
authors.initials: A
authors.lastname: Sekine
authors.forename: Tomohide
authors.initials: T
authors.lastname: Sato
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Baba
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shinohara
authors.forename: Takahiro
authors.initials: T
authors.lastname: Endo
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sogo
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Nishihira
authors.forename: Shigeru
authors.initials: S
authors.lastname: Komatsu
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Ogura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000382:microbiology*; D019907:Mycobacterium fortuitum / Q000187:drug effects / Q000302:isolation & purification*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents