Chronic recurrent multifocal osteomyelitis in a patient with selective immunoglobulin M deficiency.
Chronic recurrent multifocal osteomyelitis is an unusual inflammatory process of unknown origin involving multiple osseous sites, often recurrently. Selective immunoglobulin M (IgM) deficiency is a rare primary immunodeficiency disease, which can be associated with autoimmune diseases such as systemic lupus erythematosus, Hashimoto's disease, or hemolytic anemia. Here we report a case of a chronic recurrent multifocal osteomyelitis coexisting with selective IgM deficiency.
Makay
Balahan
B
Department of Pediatrics, Dokuz Eylul University Hospital, 35340, Balcova-Izmir, Turkey. balahan.bora@deu.edu.tr
Unsal
Erbil
E
Anal
Ozden
O
Güneş
Dilek
D
Men
Süleyman
S
Cakmakçi
Handan
H
Ozer
Erdener
E
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D018771:Arthralgia / Q000276:immunology / Q000503:physiopathology; D001327:Autoimmune Diseases / Q000097:blood / Q000276:immunology* / Q000503:physiopathology; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D002634:Chemotaxis, Leukocyte / Q000276:immunology; D002648:Child; D002908:Chronic Disease / Q000188:drug therapy; D005269:Femur / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood / Q000172:deficiency*; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010019:Osteomyelitis / Q000097:blood / Q000276:immunology* / Q000503:physiopathology; D010388:Pelvis / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology; D011877:Radionuclide Imaging; D012008:Recurrence; D013131:Spine / Q000473:pathology; D012460:Sulfasalazine / Q000627:therapeutic use; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D015415:Biomarkers; D007075:Immunoglobulin M; D012460:Sulfasalazine