Sensitivity of tests to assess improvement in ADHD symptomatology.
OBJECTIVE
To assess which measurements best predict improvement on ADHD symptomatology after medication is given.


METHODS
147 children aged 6 to 12 years, diagnosed with ADHD, participated in a double-blind placebo controlled twoweek crossover trial of methylphenidate.


RESULTS
There were statistically significant differences on all measures between placebo and medication. Effect size for the overall group was 0.33 (CGI-P), 0.80 (CGI-T), 1.33 (CGI), 0.56 (CPT), 0.82 (RASS).


CONCLUSIONS
Acute behavioural response measures, where children are observed by clinicians (RASS and CGI), were overall more reliable than parent reports in detecting improvement on ADHD symptomatology. Teacher reports were also very important, especially in the 9 to 12 year old group.
Grizenko
Natalie
N
Department of Psychiatry, McGill University.
Lachance
Martin
M
Collard
Vincent
V
Lageix
Philippe
P
Baron
Chantal
C
Ben Amor
Leila
L
Stepanian
Marina Ter
MT
Mbekou
Valentin
V
Schwartz
George
G
Bellingham
Johanne
J
Joober
Ridha
R