Organizing junctions at the cell-cell interface.
The zonula adherens (ZA) is a specialized cadherin-based structure found at the contacts between epithelial cells. Meng et al. (2008) now identify a protein complex containing the microtubule minus-end-binding protein Nezha, which provides a critical link between microtubules and cadherins in ZA biogenesis and maintenance.
Akhmanova
Anna
A
Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands. a.akhmanova@erasmusmc.nl
Yap
Alpha S
AS
D022005:Adherens Junctions / Q000378:metabolism*; D000818:Animals; D015820:Cadherins / Q000378:metabolism; D004847:Epithelial Cells / Q000166:cytology*; D006801:Humans; D007365:Intercellular Junctions; D008954:Models, Biological
D015820:Cadherins