title: [A clinical observation on therapeutic effect of colon purification on hepatic encephalopathy].
abstract: OBJECTIVE
  To observe therapeutic effect of colon purification on hepatic encephalopathy.
  
  
  METHODS
  117 patients with hepatic encephalopathy treated in our hospital were randomly divided into the treatment group (59 cases) and the control group (58 cases). Routine anti-coma hepaticum treatments were carried out in both treatment and control groups, and colon purification treatment was performed in the treatment group on basis of routine anti-coma hepaticum. The changes in symptoms and signs were observed, the grading scores of hepatic encephalopathy were evaluated, liver function was tested and blood ammonia level was determined before and after treatment in the two groups. Time for regaining consciousness was recorded after treatment in the two groups.
  
  
  RESULTS
  The symptoms and signs were obviously improved, time for regaining consciousness was shortened, the grading scores decreased, and serum aminotransferase activity and bilirubin level and blood ammonia level significantly decreased in the treatment group as compared with those of the control group. Total effective rate in the treatment was significantly higher than that in the control group and death rate in the treatment group was significantly lower than that in the control group.
  
  
  CONCLUSIONS
  Colon purification treatment is effective for hepatic encephalopathy due to cirrhosis.
authors.affiliation: Medical and Research Center for Hepatic Diseases, 150 PLA Hospital, Luoyang 471031, China
authors.forename: He-Ping
authors.initials: HP
authors.lastname: Zhao
authors.forename: Bao-Hua
authors.initials: BH
authors.lastname: Ding
authors.forename: Jian-She
authors.initials: JS
authors.lastname: Zhang
authors.forename: Shi-Min
authors.initials: SM
authors.lastname: Guo
authors.forename: Zi-Ran
authors.initials: ZR
authors.lastname: Zhang
authors.forename: Yao-Zhou
authors.initials: YZ
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D003106:Colon / Q000503:physiopathology*; D005260:Female; D006501:Hepatic Encephalopathy / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016060:Sorption Detoxification