title: Myocarditis due to oral flurbiprofen use.
abstract: We report a 23-year-old man presenting with chest pain. He denoted skin eruptions on his hands, lips, mouth, and penis 24 to 36 hours after he had taken flurbiprofen 10 days ago. Detailed examination showed an ulcerated, pitching lesion with a dimension of approximately 2x2 cm on his penis; however, other explained skin lesions were ameliorated. ST elevations were present in the electrocardiogram. Cardiac biomarkers gradually rose. The scintigraphy showed myocardial hypoperfusion in the inferoseptal wall. This phenomenon is a rare case of myocarditis due to hypersensitivity reaction. In the case of nonspecific angina pectoris accompanied by electrocardiogram changes, drug-induced myocarditis must hold a place in differential diagnoses.
authors.affiliation: Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Uzkeser
authors.affiliation: Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Mucahit
authors.initials: M
authors.lastname: Emet
authors.affiliation: Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey. Electronic address: sahinaslan29@hotmail.com.
authors.forename: Sahin
authors.initials: S
authors.lastname: Aslan
authors.affiliation: Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Cakir
authors.affiliation: Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Sule
authors.initials: S
authors.lastname: Turkyılmaz
authors.affiliation: Department of Cardiology, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Enbiya
authors.initials: E
authors.lastname: Aksakal
authors.affiliation: Department of Nucleer Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
authors.forename: Bedri
authors.initials: B
authors.lastname: Seven
mesh_terms: D000284:Administration, Oral; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005480:Flurbiprofen / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005480:Flurbiprofen