title: Acute blindness in dogs: sudden acquired retinal degeneration syndrome versus neurological disease (140 cases, 2000-2006).
abstract: OBJECTIVE
  To evaluate dogs with amaurosis and compare signalment, history, ophthalmic examination and neurologic abnormalities between dogs diagnosed with sudden acquired retinal degeneration syndrome (SARDS) versus neurological disease (ND). Animals Studied-140 dogs with acute vision loss and ocular abnormalities insufficient to account for visual deficits. An electroretinogram (ERG) was performed on each dog.
  
  
  METHODS
  Medical records were reviewed and information was collected for all dogs meeting the inclusion criteria. Dogs diagnosed with SARDS were compared to those with ND based on signalment, duration of clinical signs, past medical problems, clinicopathologic findings, and ophthalmic and physical examination abnormalities.
  
  
  RESULTS
  120 dogs were diagnosed with SARDS and 20 dogs with ND based on ERG results. Mixed-breed dogs were most commonly diagnosed with SARDS as well as ND. Pure breed dogs frequently diagnosed with SARDS included the Miniature Schnauzer and Dachshund. Dogs with SARDS did not differ significantly from those with ND based on age or sex distribution. Cushing's-like symptoms were reported more frequently in SARDS dogs as well as conjunctival hyperemia and retinal vascular attenuation. Papilledema and asymmetric visual deficits were observed more frequently in dogs with ND. Dogs with ND were no more likely than SARDS dogs to have additional neurological deficits.
  
  
  CONCLUSIONS
  Appreciable overlap of clinical signs exists between dogs with SARDS and dogs with ND resulting in acute vision loss. As a significant portion of dogs (14%) in the present study were diagnosed with ND, an ERG to rule out ND is indicated in dogs with amaurosis.
authors.affiliation: Angell Animal Medical Center WNE, 171 Union Street, Springfield, MA 01105, USA. km422@cornell.edu
authors.forename: Keith W
authors.initials: KW
authors.lastname: Montgomery
authors.forename: Alexandra
authors.initials: A
authors.lastname: van der Woerdt
authors.forename: Nancy B
authors.initials: NB
authors.lastname: Cottrill
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000818:Animals; D001766:Blindness / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D001947:Breeding; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D004596:Electroretinography / Q000379:methods / Q000662:veterinary; D005260:Female; D008297:Male; D009422:Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D012162:Retinal Degeneration / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D012189:Retrospective Studies; D012737:Sex Factors