Bag-in-the-lens: first pathological analysis of a human eye obtained postmortem.
We analyzed an enucleated eye obtained postmortem from an 86-year-old donor who had been implanted with a hydrophilic acrylic bag-in-the-lens 4 months earlier. To our knowledge, this is the first donor eye implanted with this design to undergo pathological analysis. High-frequency ultrasound showed a well-centered IOL, fixated at the level of the capsular bag. Gross and light microscopic analyses of the eye showed that if anterior and posterior capsule openings are well stretched around the optic of this IOL design, proliferative/regenerative material is potentially confined to the intercapsular space of the capsular bag remnant outside the optic rim.
Werner
Liliana
L
John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. liliana.werner@hsc.utah.edu
Tassignon
Marie-José
MJ
Gobin
Laure
L
Rozema
Jos
J
Davis
Don
D
Brubaker
Jacob
J
D000369:Aged, 80 and over; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging / Q000473:pathology*; D019923:Capsulorhexis / Q000379:methods*; D015353:Eye Enucleation; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000000981:diagnostic imaging / Q000473:pathology*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D011474:Prosthesis Design; D014019:Tissue Donors; D014463:Ultrasonography