title: Ascending thrombophlebitis after foam sclerotherapy as first symptom of breast cancer.
abstract: Malignancy increases the risk of thromboembolic events. Vascular events such as venous thromboses can even precede the diagnosis of cancer. A 48-year-old woman presented with an extensive thrombophlebitis of the left small saphenous vein and a perforating vein of the right leg after foam sclerotherapy with Aethoxysklerol foam 0.5% for small varicose veins of both lower legs. A few days later an unknown advanced breast cancer was diagnosed. This case shows that not only venous thromboses but also thrombophlebitis can be a warning sign for malignancy.
authors.affiliation: Vein Center, Ruhr University Bochum in St. Maria-Hilf Hospital, Hiltroper Landwehr 11-13, Bochum-Gerthe D-44805, Germany. s.kobus@klinikum-bochum.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Kobus
authors.forename: Stefanie
authors.initials: S
authors.lastname: Reich-Schupke
authors.forename: Lukas
authors.initials: L
authors.lastname: Pindur
authors.forename: Peter
authors.initials: P
authors.lastname: Altmeyer
authors.forename: Markus
authors.initials: M
authors.lastname: Stucker
mesh_terms: D001943:Breast Neoplasms / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015911:Sclerotherapy / Q000009:adverse effects*; D013924:Thrombophlebitis / Q000209:etiology*