title: Pre-therapy hyperfunctioning follicular thyroid carcinoma evaluation with I-131 whole-body scan and with F-18 FDG PET/CT.
abstract: We describe a patient with persistent hyperthyroidism after total thyroidectomy for toxic multinodular goiter and without therapy with levothyroxine evaluated with I-131 whole-body scan and with F-18 FDG PET/CT scan. Scintigraphy performed 48 hours after radiopharmaceutical administration showed many areas of focal radioiodine uptake. A week later we performed a PET/CT scan to better localize the anatomic site of the iodine-positive lesions. Both scans, performed after methimazole withdrawal, visualized the same lesions, and these results were used as a guide for biopsy. Histologic examination was consistent with metastatic follicular thyroid carcinoma.
authors.affiliation: Servizio di Medicina Nucleare, Ospedale Civile San Bortolo, Vicenza, Italy. porsolon@virgilio.it
authors.forename: Piergiuseppe
authors.initials: P
authors.lastname: Orsolon
authors.forename: Marcello
authors.initials: M
authors.lastname: Giachetti
authors.forename: Andrea
authors.initials: A
authors.lastname: Lupi
authors.forename: Matteo
authors.initials: M
authors.lastname: Salgarello
authors.forename: Veronica
authors.initials: V
authors.lastname: Malfatti
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Zanco
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D000368:Aged; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006019:Glycolysis; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D008297:Male; D049268:Positron-Emission Tomography; D013964:Thyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes; D019788:Fluorodeoxyglucose F18