title: An outbreak of food-borne gastroenteritis due to sapovirus among junior high school students.
abstract: The human sapovirus (SaV) causes acute gastroenteritis mainly in infants and young children. A food-borne outbreak of gastroenteritis associated with SaV occurred among junior high school students in Yokohama, Japan, during and after a study trip. The nucleotide sequences of the partial capsid gene derived from the students exhibited 98% homology to a SaV genogroup IV strain, Hu/Angelholm/SW278/2004/SE, which was isolated from an adult with gastroenteritis in Solna, Sweden. An identical nucleotide sequence was detected from a food handler at the hotel restaurant, suggesting that the causative agent of the outbreak was transmitted from the food handler. This is the first description of a food-borne outbreak associated with the SaV genogroup IV strain in Japan.
authors.affiliation: Department of Testing and Research, Yokohama City Institute of Health, Kanagawa, Japan. sh00-usuku@city.yokohama.jp
authors.forename: Shuzo
authors.initials: S
authors.lastname: Usuku
authors.forename: Makoto
authors.initials: M
authors.lastname: Kumazaki
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Kitamura
authors.forename: Osamu
authors.initials: O
authors.lastname: Tochikubo
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Noguchi
mesh_terms: D000328:Adult; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D036022:Capsid Proteins / Q000235:genetics; D002648:Child; D004196:Disease Outbreaks; D005178:Faculty; D005517:Foodborne Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012147:Restaurants; D029341:Sapovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D013334:Students
chemical_list: D036022:Capsid Proteins