title: A splenial lesion with transiently reduced diffusion in clinically mild encephalitis is not always reversible: A case report.
abstract: The MR imaging finding of a reversible splenial lesion with transiently reduced diffusion has been reported in patients with clinically mild encephalitis/encephalopathy, leading to a new clinical-radiological syndrome, clinically mild encephalitis/encephalopathy with a reversible splenial lesion. We recently experienced a 3-year-old boy with clinically mild encephalitis with a splenial lesion exhibiting transient reduced diffusion on admission. He recovered completely with no particular treatment within 2 weeks. Though the splenial lesion decreased in size, it was detected for over 5 months in T2-weighted imaging. It is suggested that a splenial lesion with transiently reduced diffusion in clinically mild encephalitis/encephalopathy is not always reversible, and could result in gliosis.
authors.affiliation: Department of Pediatrics and Radiology, Teikyo University Chiba Medical Center, Chiba, Japan. sdgcr596@ybb.ne.jp
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Takanashi
authors.forename: Keiko
authors.initials: K
authors.lastname: Kaiho
authors.forename: Katsunori
authors.initials: K
authors.lastname: Fujii
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Okubo
authors.forename: Setsuo
authors.initials: S
authors.lastname: Ota
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Kohno
mesh_terms: D002675:Child, Preschool; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D004660:Encephalitis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D016896:Treatment Outcome