title: [Theoretical evaluation of the risk of decompression illness during simulated extravehicular activity].
abstract: Theoretical analysis of the risk of decompression illness (DI) during extravehicular activity following the Russian and NASA decompression protocols (D-R and D-US, respectively) was performed. In contrast to the tradition approach to decompression stress evaluation by the factor of tissue supersaturation with nitrogen, our probabilistic theory of decompression safety provides a completely reasoned evaluation and comparison of the levels of hazard of these decompression protocols. According to this theory, the function of cumulative DI risk is equal to the sum of functions of cumulative risk of lesion of all body tissues by gas bubbles and their supersaturation by solute gases. Based on modeling of dynamics of these functions, growth of the DI cumulative risk in the course of D-R and D-US follows essentially similar trajectories within the time-frame of up to 330 minutes. However, further extension of D-US but not D-R raises the risk of DI drastically.
authors.forename: V P
authors.initials: VP
authors.lastname: Nikolaev
mesh_terms: D001784:Blood Gas Analysis; D003665:Decompression Sickness / Q000097:blood / Q000209:etiology*; D018478:Extravehicular Activity / Q000009:adverse effects*; D005740:Gases / Q000097:blood; D006801:Humans; D008962:Models, Theoretical; D009784:Occupational Diseases / Q000097:blood / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013026:Space Flight
chemical_list: D005740:Gases