title: Antifungal activity of caspofungin in combination with amphotericin B against Candida glabrata: comparison of disk diffusion, Etest, and time-kill methods.
abstract: The in vitro activities of caspofungin plus amphotericin B against 50 Candida glabrata isolates were evaluated by the time-kill, disk diffusion, and Etest methods. In vitro experiments showed a positive interaction. Even though each of these methods uses different conditions and endpoints, the results of the different methods frequently agreed.
authors.affiliation: Department of Microbiology, University of Osmangazi, Eskişehir, Turkey. idag280@gmail.com
authors.forename: Nuri
authors.initials: N
authors.lastname: Kiraz
authors.forename: Ilknur
authors.initials: I
authors.lastname: Dag
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yamac
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Kiremitci
authors.forename: Nilgun
authors.initials: N
authors.lastname: Kasifoglu
authors.forename: Yurdanur
authors.initials: Y
authors.lastname: Akgun
mesh_terms: D000666:Amphotericin B / Q000008:administration & dosage / Q000494:pharmacology*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology*; D041221:Candida glabrata / Q000187:drug effects*; D002177:Candidiasis / Q000382:microbiology; D000077336:Caspofungin; D004338:Drug Combinations; D004357:Drug Synergism; D054714:Echinocandins / Q000008:administration & dosage / Q000494:pharmacology*; D023381:Endpoint Determination; D006801:Humans; D055666:Lipopeptides; D008826:Microbial Sensitivity Tests; D013997:Time Factors
chemical_list: D000935:Antifungal Agents; D004338:Drug Combinations; D054714:Echinocandins; D055666:Lipopeptides; D000666:Amphotericin B; D000077336:Caspofungin