title: An integrative quantitative model of factors influencing the course of anorexia nervosa over time.
abstract: OBJECTIVE
  To identify factors influencing the course of anorexia nervosa (AN) over time.
  
  
  METHODS
  Former female patients with AN (36 remitted and 24 nonremitted) and 31 healthy females responded to standardized interviews and self-rating questionnaires. Remitted patients maintained normal eating, normal weight, and regular menses for the past 12 months. Patients not fulfilling these criteria were considered nonremitted.
  
  
  RESULTS
  Using logistic regression, we identified that number of hospitalizations, duration of ambulatory treatment, past vegetarianism, past anxiety, and childhood sexual abuse differentiated remitted from nonremitted patients, predicting nonremission. A similar analysis identified that elevated follow-up vegetarianism and eating-related concerns and lower body mass index (BMI) differentiated remitted from nonremitted patients, contributing to nonremission. Univariate analyses identified that remitted patients had elevated anxiety and eating-related obsessionality compared with the controls, suggesting these variables to potentially predispose to AN.
  
  
  CONCLUSIONS
  Elevated anxiety and eating-related obsessionality may increase the risk for the development of AN and for nonremission.
authors.affiliation: School of Nutritional Sciences, Faculty of Agricultural, Food, and Environmental Quality Sciences, Rehovot.
authors.forename: Michal
authors.initials: M
authors.lastname: Yackobovitch-Gavan
authors.forename: Moria
authors.initials: M
authors.lastname: Golan
authors.forename: Avi
authors.initials: A
authors.lastname: Valevski
authors.forename: Shulamit
authors.initials: S
authors.lastname: Kreitler
authors.forename: Eytan
authors.initials: E
authors.lastname: Bachar
authors.forename: Amia
authors.initials: A
authors.lastname: Lieblich
authors.forename: Edith
authors.initials: E
authors.lastname: Mitrani
authors.forename: Abraham
authors.initials: A
authors.lastname: Weizman
authors.forename: Daniel
authors.initials: D
authors.lastname: Stein
mesh_terms: D000704:Analysis of Variance; D000856:Anorexia Nervosa / Q000453:epidemiology* / Q000517:prevention & control / Q000523:psychology; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000523:psychology; D015992:Body Mass Index; D016022:Case-Control Studies; D015897:Comorbidity; D014676:Diet, Vegetarian / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D016015:Logistic Models; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology* / Q000523:psychology; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012008:Recurrence; D012307:Risk Factors; D012742:Sex Offenses; D055815:Young Adult