Drug-induced liver injury: hepatotoxicity of quetiapine revisited.
Drug hepatotoxicity is the most common cause of fulminant hepatic failure in the USA. We describe a rare case of a patient who developed an acute liver injury after initiation of therapy with quetiapine, but after conservative management and a trial of steroids, has fully recovered. This is the second reported case of quetiapine-induced liver injury in the published literature.
Shpaner
Alexander
A
Division of Gastroenterology and Hepatology, University Health Science Center at Houston, Houston, Texas 77030, USA. Alexander.Shpaner@uth.tmc.edu
Li
Wei
W
Ankoma-Sey
Victor
V
Botero
Rafael Claudino
RC
D000208:Acute Disease; D014150:Antipsychotic Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced / Q000473:pathology; D003987:Dibenzothiazepines / Q000009:adverse effects*; D006801:Humans; D008297:Male; D000069348:Quetiapine Fumarate; D055815:Young Adult
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate