title: Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome.
abstract: OBJECTIVE
  Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared with nonprocessed cereals.
  
  
  METHODS
  This investigation is a randomized double-blind, cross-over multicentre prospective study of 26 intestinal resected out patients, considered as short bowel syndrome patients. The patients were divided into groups A or B, in accordance with the first allocated treatment. Subgroup analyses of the underlying diagnoses and type of surgical procedure were performed. The studied parameters were faecal volume, nocturnal stools, abdominal pain/discomfort, health-related quality of life, peripheral blood tests and anthropometric data.
  
  
  RESULTS
  In both groups, intake of nonprocessed cereals significantly decreased the faecal volume. The subgroup analyses of patients with a history of ulcerative colitis (compared with Crohn's disease) and nonileostomy-operated procedure (compared with ileostomi-operated procedure) showed significantly decreased faecal volume during nonprocessed cereals intake. Peripheral blood tests, quality of life and anthropometry were not affected.
  
  
  CONCLUSIONS
  In this study, nonprocessed cereals seemed to be as effective as specially processed cereals in decreasing faecal volume in general and especially in ulcerative colitis patients (mainly operated with nonileostomy techniques). Our results indicate that use of supplementary cereals is safe for this group of patients, but should optimally include evaluation of the underlying diagnosis and the surgical method used.
authors.affiliation: Department of Internal Medicine, Gastroenterology Unit, Sahlgren's University Hospital, Göteborg, Sweden. maria.pagoldh@vgregion.se
authors.forename: Maria
authors.initials: M
authors.lastname: Pagoldh
authors.forename: Anders
authors.initials: A
authors.lastname: Eriksson
authors.forename: Erling
authors.initials: E
authors.lastname: Heimtun
authors.forename: Eva
authors.initials: E
authors.lastname: Kvifors
authors.forename: Berit
authors.initials: B
authors.lastname: Sternby
authors.forename: Lars
authors.initials: L
authors.lastname: Blomquist
authors.forename: Annika
authors.initials: A
authors.lastname: Lapidus
authors.forename: Ole
authors.initials: O
authors.lastname: Suhr
authors.forename: Stefan
authors.initials: S
authors.lastname: Lange
authors.forename: Urban
authors.initials: U
authors.lastname: Karlbom
authors.forename: Daniel
authors.initials: D
authors.lastname: Nordström
authors.forename: Björn
authors.initials: B
authors.lastname: Rettrup
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D003093:Colitis, Ulcerative / Q000503:physiopathology / Q000601:surgery; D003424:Crohn Disease / Q000503:physiopathology / Q000601:surgery; D018592:Cross-Over Studies; D003672:Defecation; D004040:Dietary Carbohydrates / Q000627:therapeutic use*; D004311:Double-Blind Method; D002523:Edible Grain; D005243:Feces; D005260:Female; D005511:Food Handling; D006801:Humans; D007422:Intestines / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000178:diet therapy / Q000503:physiopathology; D012778:Short Bowel Syndrome / Q000178:diet therapy* / Q000209:etiology / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D004040:Dietary Carbohydrates