title: Risk factors for operative morbidity and mortality in gastric cancer patients undergoing total gastrectomy.
abstract: OBJECTIVE
  To study the risk factors for morbidity and mortality following total gastrectomy.
  
  
  METHODS
  We retrospectively reviewed the records of 125 consecutive patients who underwent total gastrectomy for gastric cancer at the Second Affiliated Hospital of Zhejiang University School of Medicine between January 2003 and March 2008.
  
  
  RESULTS
  The overall morbidity rate was 20.8% (27 patients) and the mortality rate was 3.2% (4 patients). Morbidity rates were higher in patients aged over 60 [odds ratio (OR) 4.23 (95% confidence interval (CI) 1.09 to 12.05)], with preoperative comorbidity [with vs without, OR 1.25 (95% CI 1.13 to 8.12)], when the combined resection was performed [combined resection vs total gastrectomy only, OR 2.67 (95% CI 1.58 to 5.06)].
  
  
  CONCLUSIONS
  Age, preoperative comorbidity and combined resection were independently associated with the rate of morbidity after total gastrectomy for gastric cancer.
authors.affiliation: Department of Surgery, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Dao-Jun
authors.initials: DJ
authors.lastname: Gong
authors.forename: Chao-Feng
authors.initials: CF
authors.lastname: Miao
authors.forename: Qi
authors.initials: Q
authors.lastname: Bao
authors.forename: Ming
authors.initials: M
authors.lastname: Jiang
authors.forename: Li-Fang
authors.initials: LF
authors.lastname: Zhang
authors.forename: Xiao-Tao
authors.initials: XT
authors.lastname: Tong
authors.forename: Li
authors.initials: L
authors.lastname: Chen
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality* / Q000601:surgery*