title: Pulmonary hypertension secondary to left ventricular systolic dysfunction: contemporary diagnosis and management.
abstract: Pulmonary hypertension secondary to left ventricular systolic dysfunction is often a poor prognostic marker in chronic heart failure. In this article, we review evidence supporting modern strategies addressing pulmonary hypertension in patients with left ventricular systolic dysfunction, including right-sided heart catheterization with vasoreactivity testing and subsequent parenteral, oral, and inhaled therapy. We delineate a diagnostic approach to secondary pulmonary hypertension and outline evidence-based therapeutic strategies for management in acute and chronic heart failure.
authors.affiliation: Department of Medicine, Massachusetts General Hospital, Grey Bigelow 8, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: Ravi V
authors.initials: RV
authors.lastname: Shah
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Semigran
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy*; D011379:Prognosis; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000150:complications*