title: Primary lymphoma of the ovary.
abstract: Involvement of the ovary by malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma is rare. We report a case of primary ovarian non-Hodgkin's lymphoma with bilateral involvement which was managed by surgery and chemotherapy. A 29-year-old woman was admitted with signs and symptoms suggestive of an ovarian cancer. Computed tomography revealed an abdominal tumor measuring 20 cm in diameter, without enlarged lymph nodes. The diagnosis of malignant lymphoma was established after bilateral adnexectomy and histological study of the excised tissue. The tumor was classified as a diffuse large B-cell lymphoma. The patient has been advised 8 cycles of standard CHOP regimen and is presently on treatment. She has now been without disease for 7 months after the surgery. According to previous reports the treatment principles and prognosis of primary ovarian lymphoma is the same as that of other nodal lymphomas.
authors.affiliation: Department of Surgery, National Institute of Oncology, Rabat, Morocco.
authors.forename: Tijani
authors.initials: T
authors.lastname: Elharroudi
authors.forename: Nabil
authors.initials: N
authors.lastname: Ismaili
authors.forename: Hassan
authors.initials: H
authors.lastname: Errihani
authors.forename: Abdelouahed
authors.initials: A
authors.lastname: Jalil
mesh_terms: D000328:Adult; D000951:Antigens, Neoplasm / Q000737:chemistry; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D049268:Positron-Emission Tomography / Q000379:methods; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000951:Antigens, Neoplasm; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone