title: Lighting up the stressed ER.
abstract: Balancing the capacity for protein maturation with changes in protein flux through the endoplasmic reticulum (ER) is crucial for maintaining ER homeostasis. In this issue, Merksamer et al. (2008) exploit a redox-sensitive fluorescent protein to monitor the environment inside the ER of living yeast, illuminating how this organelle responds to different perturbations.
authors.affiliation: National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Sang-Wook
authors.initials: SW
authors.lastname: Kang
authors.forename: Ramanujan S
authors.initials: RS
authors.lastname: Hegde
mesh_terms: D004721:Endoplasmic Reticulum / Q000502:physiology*; D010084:Oxidation-Reduction; D017510:Protein Folding; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D013312:Stress, Physiological