Production of transgenic rodents by the microinjection of cloned DNA into fertilized one-celled eggs.
Murphy
David
D
Laboratories of Integrative Neurosciences and Endocrinology, University of Bristol, Bristol, UK.
D000827:Animal Welfare; D000818:Animals; D030801:Animals, Genetically Modified / Q000196:embryology / Q000235:genetics; D000830:Animals, Laboratory; D002970:Cleavage Stage, Ovum / Q000166:cytology; D003001:Cloning, Molecular; D004247:DNA / Q000008:administration & dosage / Q000737:chemistry*; D037901:Euthanasia, Animal / Q000379:methods; D005306:Fertilization / Q000502:physiology*; D018014:Gene Transfer Techniques; D007756:Laboratory Animal Science / Q000379:methods; D051379:Mice; D008845:Microinjections / Q000379:methods*; D051381:Rats; D012377:Rodentia / Q000235:genetics*
D004247:DNA