Low toxic, thermoresponsive dendrimers based on oligoethylene glycols with sharp and fully reversible phase transitions.
Novel first (G1) and second (G2) generation dendrimers based on three-fold branched oligoethylene glycol dendrons are efficiently synthesized which show characteristic thermoresponsive behavior and negligible cytotoxicity (for G2).
Li
Wen
W
Institute of Polymers, Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10, HCI G525, 8093, Zurich, Switzerland.
Zhang
Afang
A
Chen
Yong
Y
Feldman
Kirill
K
Wu
Hua
H
Schlüter
A Dieter
AD
D000818:Animals; D002460:Cell Line; D045744:Cell Line, Tumor; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D006801:Humans; D051379:Mice; D015394:Molecular Structure; D044367:Phase Transition; D011092:Polyethylene Glycols / Q000737:chemistry*
D050091:Dendrimers; D011092:Polyethylene Glycols