title: Increased interaction of proteins in nuclear extract from mouse liver and lung tumors with TATA-containing oligonucleotide.
abstract: Increased TATA-binding activity of proteins in nuclear extracts from murine hepatocarcinoma HA-1 and murine Lewis lung adenocarcinoma was demonstrated. The dependence of the amount of formed complexes on protein concentration, displacement of labeled 32P-TATA-containing oligonucleotide by its unlabeled analog, and weak interaction with an oligonucleotide containing damaged TATA box confirm specificity of the formed complexes.
authors.affiliation: Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk.
authors.forename: M V
authors.initials: MV
authors.lastname: Lysova
authors.forename: T V
authors.initials: TV
authors.lastname: Arshinov
authors.forename: I A
authors.initials: IA
authors.lastname: Drachkova
authors.forename: V F
authors.initials: VF
authors.lastname: Kobzev
authors.forename: V I
authors.initials: VI
authors.lastname: Kaledin
authors.forename: L K
authors.initials: LK
authors.lastname: Savinkova
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics / Q000378:metabolism; D000818:Animals; D008113:Liver Neoplasms / Q000235:genetics / Q000378:metabolism*; D008175:Lung Neoplasms / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D009841:Oligonucleotides / Q000235:genetics / Q000378:metabolism; D016385:TATA Box; D035181:TATA-Box Binding Protein / Q000235:genetics / Q000378:metabolism; D014020:Tissue Extracts / Q000737:chemistry*
chemical_list: D009687:Nuclear Proteins; D009841:Oligonucleotides; D035181:TATA-Box Binding Protein; D014020:Tissue Extracts