Primary ovarian carcinoid tumor with luteinized stromal cells.
BACKGROUND
Primary ovarian carcinoid tumors are rare. Distinct histologic patterns have been described in the literature as insular, trabecular, mucinous and mixed types.


METHODS
We describe a case of 71-year-old woman diagnosed with a left ovarian tumor. Frozen section examination identified the mass as a sex-cord stromal tumor. The surgically resected tumor was diagnosed as an insular carcinoid tumor with unusual luteinized stromal cells. Histologic diagnosis complied with results acquired by immunohistochemical with positivity of tumor cells for neuroendocrine markers and positivity of luteinized stromal cells for alpha-inhibin, calretinin and Melan A.


CONCLUSIONS
Ovarian carcinoid tumor can be extremely heterogeneous. The purpose of our report was to show that the ovarian carcinoid tumor can be associated with stromal luteinization, mimicking a sex-cord stromal tumor.
Engohan-Aloghe
Corinne
C
Department of Pathology, Erasme University Hospital, Free University of Brussels, CP 610, Route de Lennik 808, Brussels 1070, Belgium. corinenken@yahoo.fr
Buxant
F
F
Noël
J C
JC
D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007150:Immunohistochemistry; D034461:Luteinization; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology