[Hyperammoniemia and central pontine myelinolysis in a patient with Sjögren syndrome and chronic valproate use].
The authors describe a case of a drug-associated hyperammonemia, central pontine myelinolysis and coma occurring in a patient with Sjögren's syndrome chronically treated with valproic acid for an underlying psychotic disorder. The possible differential diagnoses are reviewed and discussed.
Berlot
Giorgio
G
UCO di Anestesia, Rianimazione e Terapia Antalgica, Trieste. berlot@inwind.it
Battaglia
Katiuscia
K
Ukmar
Maja
M
D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D022124:Hyperammonemia / Q000139:chemically induced*; D017590:Myelinolysis, Central Pontine / Q000139:chemically induced*; D012859:Sjogren's Syndrome / Q000150:complications*; D014635:Valproic Acid / Q000009:adverse effects*
D018692:Antimanic Agents; D014635:Valproic Acid