title: A liposomal delivery vehicle for the anticancer agent gossypol.
abstract: BACKGROUND
  Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol.
  
  
  METHODS
  Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity.
  
  
  RESULTS
  Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells.
  
  
  CONCLUSIONS
  Liposomes can be used effectively as gossypol carriers.
authors.affiliation: College of Pharmacy, Shandong University, Jinan 250012, P. R. China.
authors.forename: Guangxi
authors.initials: G
authors.lastname: Zhai
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Zhao
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Lu
authors.forename: Weiping
authors.initials: W
authors.lastname: Ye
authors.forename: Young C
authors.initials: YC
authors.lastname: Lin
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Lee
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000737:chemistry; D045744:Cell Line, Tumor; D006072:Gossypol / Q000008:administration & dosage* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D007624:KB Cells; D008081:Liposomes / Q000008:administration & dosage* / Q000737:chemistry; D010743:Phospholipids / Q000008:administration & dosage / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D008081:Liposomes; D010743:Phospholipids; D006072:Gossypol