title: Basal metabolic rate and body composition in patients with post-polio syndrome.
abstract: The aim of this study was to compare basal metabolic rate (BMR) of post-polio syndrome (PPS) patients with healthy individuals and to determine its correlation to body composition. BMR (kcal/day) was determined by indirect calorimetry and body composition by dual energy X-ray absorptiometry. BMR was lower in the PPS patient group than in the control group, although it was similar in both groups when adjusted for body surface area, total body mass (TBM), lean body mass (LBM) and fat-free mass (FFM). PPS patients also showed reduced TBM, LBM and FFM in relation to controls. As muscle energy expenditure while at rest contributes only 20% to the BMR, a proportional reduction in BMR and FFM or LBM could suggest that muscle mass or other factors may interfere more than predicted. It was concluded that the prediction of BMR from the Harris-Benedict equation in PPS patients must be carefully reviewed.
authors.affiliation: Department of Physiology, Neuromuscular Diseases Division, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: J V
authors.initials: JV
authors.lastname: Bargieri
authors.forename: A A J
authors.initials: AA
authors.lastname: Quadros
authors.forename: R D B
authors.initials: RD
authors.lastname: Pereira
authors.forename: A J B
authors.initials: AJ
authors.lastname: Oliveira
authors.forename: M
authors.initials: M
authors.lastname: Lazaretti-Castro
authors.forename: A C
authors.initials: AC
authors.lastname: Silva
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D001481:Basal Metabolism / Q000502:physiology*; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002153:Calorimetry, Indirect / Q000379:methods; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D016262:Postpoliomyelitis Syndrome / Q000378:metabolism* / Q000503:physiopathology*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity