Leuconostoc septicemia in a preterm neonate on vancomycin therapy: case report and literature review.
We report the case of a 26-day-old premature infant born at 24 weeks' gestation who developed septicemia while receiving vancomycin therapy. The blood isolate initially identified as a vancomycin-resistant Streptococcous viridans was found to be Leuconostoc spp. Her condition improved with parenteral ampicillin and gentamicin therapy and removal of the intravenous central catheter. Prematurity is a recognized risk factor for Leuconostoc disease. Clinicians need to consider Leuconostoc spp. when vancomycin-resistant pathogens are identified and provide appropriate therapy.
Janow
Ginger
G
Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, New York, USA.
Lambert
Binta
B
Scheiner
Melissa
M
Rosen
Orna
O
Goldman
David L
DL
Soghier
Lamia
L
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000382:microbiology*; D019102:Infant, Very Low Birth Weight; D007934:Leuconostoc / Q000302:isolation & purification*; D012307:Risk Factors; D018805:Sepsis / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis; D014640:Vancomycin / Q000627:therapeutic use; D020713:Vancomycin Resistance; D034363:Viridans Streptococci / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D014640:Vancomycin