Short communication: Molecular characterization of HIV type 1 BF pol recombinants from São Paulo, Brazil.
In the Brazilian HIV-1 epidemic, subtypes B, C, and F1 are cocirculating in the population. Sequences of the partial pol gene from 463 HIV-1-infected patients were obtained from plasma samples and viral subtype was characterized. BF recombinants were found in 8% of the samples. Fifteen different patterns were observed. A CRF28_BF and CRF29_BF structure was found in 29.7% of the samples, CRF12_BF in 13.5%, and CRF39_BF in 2.7%. Two other patterns were identified in each of three samples. These findings could indicate a new CRF description, but to determine this a full length study is required.
de Souza
Ana Carolina Mamana Fernandes
AC
Instituto de Medicina Tropical, Universidade de São Paulo, Laboratório de Virologia, LIM52, São Paulo, SP, Brazil.
de Oliveira
Cristina Mendes
CM
Rodrigues
Célia Luiza de Lima
CL
Silva
Synara Alexandre Araújo
SA
Levi
José Eduardo
JE
D001938:Brazil / Q000453:epidemiology; D016000:Cluster Analysis; D005838:Genotype; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D010949:Plasma / Q000821:virology; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA; D054302:pol Gene Products, Human Immunodeficiency Virus / Q000235:genetics*
D054302:pol Gene Products, Human Immunodeficiency Virus