Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle.
This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH12 and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.
de Souza Reis
Luis Souza
LS
Universidade do Oeste Paulista-UNOESTE, Pós-gradu ção em Ciência Animal, Presidente Prudente-SP, CEP 19067-175, Brasil. reis.lsls@gmail.com
Frazatti-Gallina
Neuza Maria
NM
de Lima Paoli
Rosana
R
Giuffrida
Rogerio
R
Albas
Avelino
A
Oba
Eunice
E
Pardo
Paulo Eduardo
PE
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D004306:Dose-Response Relationship, Immunologic; D004334:Drug Administration Schedule; D004347:Drug Interactions; D031168:Matricaria / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000276:immunology*
D000914:Antibodies, Viral; D010936:Plant Extracts; D011819:Rabies Vaccines