title: A novel pressure-driven piezodispenser for nanoliter volumes.
abstract: A successful dispensing device has been built for use in biotechnology applications requiring nanoliter volume liquid transfer. Air pressure is used as the primary driving force and is controlled via a high speed miniature solenoid valve as opposed to many existing systems that use a valve in line with constantly pressurized fluid to start and stop the dispensing action. This automated pressure-driven system is used to improve a typical piezodriven microdispenser. The resulting system is much less prone to failures resulting from air entrainment and can dispense much higher viscosity fluids than the microdispenser alone.
authors.affiliation: Genomation Laboratory, University of Washington, P.O. Box 352500, Seattle, Washington 98195-2500, USA.
authors.forename: Shawn
authors.initials: S
authors.lastname: McGuire
authors.forename: Charles
authors.initials: C
authors.lastname: Fisher
authors.forename: Mark
authors.initials: M
authors.lastname: Holl
authors.forename: Deirdre
authors.initials: D
authors.lastname: Meldrum
mesh_terms: D001274:Atmospheric Pressure; D001709:Biotechnology / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D008832:Microchemistry / Q000295:instrumentation* / Q000379:methods; D008845:Microinjections / Q000295:instrumentation*; D008904:Miniaturization; D008967:Molecular Biology / Q000295:instrumentation*; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D014783:Viscosity