title: [Data analysis of the objective observation parameters of benign prostatic hyperplasia patients accepting different treatment regimens].
abstract: OBJECTIVE
  To observe different objective observation parameters of the benign prostatic hyperplasia (BPH) patients accepting different treatment strategies, and to further analyze the relationship of these factors with the treatment option.
  
  
  METHODS
  Three hundred and twenty-nine BPH patients, aged 50-80, were assigned into 3 groups jointly decided by the physicians and patients based on the individual conditions and the patients' willingness: watchful waiting group (n=61), aged (63 +/- 8), drug treatment group (n=179), aged (68 +/- 7), and operation group (n=89), aged (71 +/- 6). The data of prostate volume, prostate specific antigen (PSA), maximum flow rate (Qmax), average flow rate, urinating volume, and residual urine volume before treatment were recorded.
  
  
  RESULTS
  The prostate volume of the watchful waiting group was 33.0 ml, significantly smaller then those of the drug treatment and operation groups (40.1 and 65.5 ml respectively, both P < 0.01); the Qmax of the watchful waiting group was 17.1 ml/s, significantly higher than those of the drug treatment and operation groups (12.4 and 9.1 ml/s respectively, both P < 0.01), and the urinating volume of the watchful waiting group was 332 ml, significantly more than those of the drug treatment and operation groups (247 and 188 ml respectively, both P < 0.01). The serum PSA of the operation group was 5.44 ng/ml, significantly higher than those of the watchful waiting and drug treatment groups (1.53 and 1.99 ng/ml respectively, both P < 0.01); and the residual urine volume of the operation group was 208 ml, significantly higher than those of the watchful waiting and drug treatment groups (21 and 45 ml respectively, both P < 0.01). There were no significant differences in the serum PSA and residual urine volume between the drug treatment and watchful waiting groups.
  
  
  CONCLUSIONS
  Prostate volume, PSA, Qmax, average flow rate, urinating volume, and residual urine volume are important influential factors influencing the treatment option of BPH. Data analysis of the objective observation parameters will be helpful in clinical decision making.
authors.affiliation: Department of Urology, Beijing Hospital, Beijing 100730, China.
authors.forename: Yao-guang
authors.initials: YG
authors.lastname: Zhang
authors.forename: Jian-ye
authors.initials: JY
authors.lastname: Wang
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
authors.forename: Ben
authors.initials: B
authors.lastname: Wan
authors.forename: Dong
authors.initials: D
authors.lastname: Wei
authors.forename: Shu-min
authors.initials: SM
authors.lastname: Deng
authors.forename: Jin
authors.initials: J
authors.lastname: Xu
authors.forename: Jian-ye
authors.initials: JY
authors.lastname: Wu
authors.forename: Xin
authors.initials: X
authors.lastname: Chu
authors.forename: Ping
authors.initials: P
authors.lastname: Zeng
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000706:statistics & numerical data; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000097:blood / Q000473:pathology / Q000628:therapy*
chemical_list: D017430:Prostate-Specific Antigen