title: Case series: Sensory intolerance as a primary symptom of pediatric OCD.
abstract: BACKGROUND
  Marked intolerance or intrusive re-experiencing of ordinary sensory stimuli that in turn drive functionally impairing compulsive behaviors are occasionally seen in young children with OCD.
  
  
  METHODS
  We describe a number of children with DSM-IV OCD ascertained from a family genetic study of pediatric OCD, whose intolerance of ordinary sensory stimuli created significant subjective distress and time-consuming ritualistic behavior that was clinically impairing.
  
  
  RESULTS
  In each case, these sensory symptoms were the primary presenting symptoms and were experienced in the absence of intrusive thoughts, images, or ideas associated with "conventional" OCD symptoms.
  
  
  CONCLUSIONS
  These symptoms suggest abnormalities in sensory processing and integration in at least a subset of OCD patients. Recognition of these sensory symptoms and sensory-driven behaviors as part of the broad phenotypic variation in children with OCD could help clinicians more easily identify OCD patients and facilitate treatment.
authors.affiliation: Clinical Research Program in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Eric P
authors.initials: EP
authors.lastname: Hazen
authors.forename: Elizabeth L
authors.initials: EL
authors.lastname: Reichert
authors.forename: John C
authors.initials: JC
authors.lastname: Piacentini
authors.forename: Eurípedes Constantino
authors.initials: EC
authors.lastname: Miguel
authors.forename: Maria Conceição
authors.initials: MC
authors.lastname: do Rosario
authors.forename: David
authors.initials: D
authors.lastname: Pauls
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Geller
mesh_terms: D000293:Adolescent; D001143:Arousal; D001288:Attention; D002648:Child; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D010552:Personality Assessment / Q000706:statistics & numerical data; D011594:Psychometrics; D012307:Risk Factors; D012678:Sensation Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D055139:Sensory Gating; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D005879:Tourette Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors