title: [Prevalence of Actinobacillus actinomycetemcomitans in saliva of different types of periodontitis].
abstract: OBJECTIVE
  To investigate the prevalence of Actinobacillus actinomycetemcomitans (Aa) in whole saliva of different types of periodontitis and compare the detections of Aa between saliva and pooled subgingival plaque sample, and analyze the relationship between Aa and clinical conditions.
  
  
  METHODS
  Unstimulated whole saliva samples and pooled subgingival samples were collected from 50 aggressive periodontitis (AgP) patients, 48 chronic periodontitis (CP) patients and 25 subjects with no periodontitis, and Aa was detected in these samples by PCR method.
  
  
  RESULTS
  The prevalence of Aa in whole saliva of AgP patients was significantly higher than in subjects with no periodontitis (32% vs. 4%, P<0.01) and CP patients (32% vs. 15%, P<0.05). Aa was also more frequently detected in whole saliva sample than in pooled subgingival sample of AgP patients (32% vs. 16%, P<0.05). Subjects younger than 30 years old were more likely to present Aa in whole saliva ( OR = 3.23, P<0.05) and percentage of sites with bleeding index (BI) > or = 3 over 70% was a risk indicator for the presence of Aa in whole saliva
  
  
  CONCLUSIONS
  The detection of Aa in whole saliva sample of AgP patients was more frequent than in pooled subgingival plaque samples, and also more frequent than in CP patients and subjects with no periodontitis, which suggest that Aa may participate in the initiation and progression of aggressive periodontitis.
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Xiang-hui
authors.initials: XH
authors.lastname: Feng
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Huan-xin
authors.initials: HX
authors.lastname: Meng
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Zhi-bin
authors.initials: ZB
authors.lastname: Chen
authors.forename: Dong
authors.initials: D
authors.lastname: Shi
mesh_terms: D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification*; D055113:Chronic Periodontitis / Q000382:microbiology*; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000382:microbiology; D012463:Saliva / Q000382:microbiology*; D055815:Young Adult