First synthesis of non-symmetrical "phthalimidoyl active ester" bi-dentate cross-linking reagents having an acid chloride, 2-benzothiazole, or 1-benzotriazol group.
For the purpose of modification of a variety of derivatives, including biologically important compounds, such as sugar derivatives and proteins etc., we have first synthesized several non-symmetrical bi-dentate cross-linking reagents, namely 3-(phthalimidoyloxycarbonyl)butyric acid chloride (1), 4-(2-benzothiazolyloxycarbonyl)butyric-N-hydroxyphthalimide ester (4) and 4-(1-benzotriazoleoxa)butyric-N-hydroxyphthalimide ester (5).
Sheikh
Md Chanmiya
MC
Department of Material Systems Engineering and Life Science, Faculty of Engineering, University of Toyama, 3190 Gofuku, Toyama, 930-8555, Japan.
Takagi
Shunsuke
S
Sakai
Mebumi
M
Abe
Hitoshi
H
Morita
Hiroyuki
H
D000941:Antigens / Q000737:chemistry / Q000378:metabolism; D001596:Benzylamines / Q000737:chemistry / Q000378:metabolism; D002712:Chlorides / Q000737:chemistry*; D002784:Cholesterol / Q000737:chemistry / Q000378:metabolism; D003432:Cross-Linking Reagents / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000737:chemistry*; D010797:Phthalimides / Q000737:chemistry*; D011506:Proteins / Q000378:metabolism; D013379:Substrate Specificity; D013844:Thiazoles / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
D000941:Antigens; D001596:Benzylamines; D002712:Chlorides; D003432:Cross-Linking Reagents; D004952:Esters; D010797:Phthalimides; D011506:Proteins; D013844:Thiazoles; D014230:Triazoles; C037431:phthalimide; D002784:Cholesterol; C030796:benzylamine