title: Synthesis, characterization, and antifungal activity of boron-containing thiosemicarbazones.
abstract: Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2-formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1-benzodiazaborines. All new compounds have been investigated for potential antifungal activity.
authors.affiliation: Department of Chemistry, Mount Allison University, Sackville NB E4L1G8, Canada.
authors.forename: Justin W
authors.initials: JW
authors.lastname: Hicks
authors.forename: Christian B
authors.initials: CB
authors.lastname: Kyle
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Vogels
authors.forename: Susan L
authors.initials: SL
authors.lastname: Wheaton
authors.forename: Felix J
authors.initials: FJ
authors.lastname: Baerlocher
authors.forename: Andreas
authors.initials: A
authors.lastname: Decken
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Westcott
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D013882:Thiosemicarbazones