title: Diffusion tensor imaging of hemispheric asymmetries in the developing brain.
abstract: Diffusion tensor imaging (DTI) was performed in 39 right-handed children to examine structural hemispheric differences and the impact of age, socioeconomic status, and sex on these differences. Apparent diffusion coefficient (ADC) values were smaller in the left than in the right temporal, prefrontal, anterior internal capsular and the thalamic regions, and fractional anisotropy (FA) values were larger in the left than in the right internal capsule, thalamus, and cingulate. Significant region-by-sex interactions disclosed that the relation of DTI asymmetries to performance depended on sex including the relation of temporal lobes to reading comprehension and the relation of frontal lobes to solving applied mathematical problems.
authors.affiliation: Physical Medicine and Rehabilitation Alliance of Baylor College of Medicine and the University of Texas-Houston Medical School, Houston, TX 77030, USA. ewilde@bcm.edu
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Wilde
authors.forename: Stephen R
authors.initials: SR
authors.lastname: McCauley
authors.forename: Zili
authors.initials: Z
authors.lastname: Chu
authors.forename: Jill V
authors.initials: JV
authors.lastname: Hunter
authors.forename: Erin D
authors.initials: ED
authors.lastname: Bigler
authors.forename: Ragini
authors.initials: R
authors.lastname: Yallampalli
authors.forename: Zhiyue J
authors.initials: ZJ
authors.lastname: Wang
authors.forename: Gerri
authors.initials: G
authors.lastname: Hanten
authors.forename: Xiaoqi
authors.initials: X
authors.lastname: Li
authors.forename: Marco A
authors.initials: MA
authors.lastname: Ramos
authors.forename: Sharjeel H
authors.initials: SH
authors.lastname: Sabir
authors.forename: Ana C
authors.initials: AC
authors.lastname: Vasquez
authors.forename: Deleene
authors.initials: D
authors.lastname: Menefee
authors.forename: Harvey S
authors.initials: HS
authors.lastname: Levin
mesh_terms: D000293:Adolescent; D000367:Age Factors; D016880:Anisotropy; D001921:Brain / Q000033:anatomy & histology* / Q000254:growth & development*; D001931:Brain Mapping; D002648:Child; D002657:Child Development / Q000502:physiology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D012737:Sex Factors; D012959:Socioeconomic Factors