[Effect of NaFeEDTA on serum ferritin level in iron deficient epidemic population: a systematic review].
OBJECTIVE
To evaluate effect of NaFeEDTA on serum ferritin level in iron deficient epidemic population.


METHODS
A comprehensive literature retrieval was performed via searching electronic databases, hand searching bibliographies of books and relevant journals, collecting grey literatures, looking into conference abstracts, contacting fields experts and reviewing references and citations. Criteria from Cochrane EPOC review group were used to assess the quality of the included studies. Generic inverse variance method was used to undertake Meta-analysis.


RESULTS
The pooled estimate for serum ferritin level (weighted mean difference) was 1.58 microg/L (95% CI 1.20-2.09; P < 0.001).


CONCLUSIONS
This systematic review indicates that NaFeEDTA might improve serum ferritin concentration significantly in iron deficient epidemic population.
Wang
Bo
B
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Key Laboratory of Epidemiology, Ministry of Education, Beijing 100083, China.
Zhan
Si-yan
SY
Xia
Yin-yin
YY
Li
Li-ming
LM
D018798:Anemia, Iron-Deficiency / Q000188:drug therapy*; D004492:Edetic Acid / Q000627:therapeutic use; D005290:Ferric Compounds / Q000627:therapeutic use*; D005293:Ferritins / Q000097:blood*; D006801:Humans; D019266:Iron, Dietary; D016032:Randomized Controlled Trials as Topic
D005290:Ferric Compounds; D019266:Iron, Dietary; D005293:Ferritins; D004492:Edetic Acid; C019179:Fe(III)-EDTA