title: A new route to multifunctionalized p-terphenyls and heteroaryl analogues via [5C + 1C(N)] annulation strategy.
abstract: p-Terphenyls and heteroaryl analogues including bipyridines were prepared via [5C + 1C(N)] annulation of alpha-aryl-alpha-alkenoyl ketene-(S,S)-acetals (five carbon 1,5-bielectrophilic species) with nitroethane or ammonium acetate. The reaction features mild conditions, multisubstitution, and functional group tolerance and is metal catalyst free. The present protocol provides a new alternative to the conventional methodologies for the synthesis of teraryls.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Fushun
authors.initials: F
authors.lastname: Liang
authors.forename: Xin
authors.initials: X
authors.lastname: Cheng
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*; D013730:Terphenyl Compounds / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D013730:Terphenyl Compounds; D002244:Carbon; C116609:3-hydroxybutanal; D009584:Nitrogen