title: Risk factors in community-acquired/onset urinary tract infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.
abstract: We investigated the risk factors for community acquired/onset urinary tract infections due to extended spectrum beta-lactamase (ESBL)-positive Escherichia coli or Klebsiella pneumoniae in 62 patients who were followed-up from August 1, 2003 to September 1, 2006. Sixty patients with community-acquired urinary tract infections caused by ESBL-negative E. coli or K. pneumoniae who were followed-up during the same dates were included as a control group. Age (> or =65 or <65 years old), sex, bladder cancer, benign prostate hypertrophy (BPH), prostate cancer, urolithiasis, urethral catheter, previous urological operation, diabetes mellitus, use of antibiotics during the last 3 months and hospitalization during the last 3 months were investigated as risk factors. The presence of previous urological operation and quinolone or cephalosporin use for any infection during the last 3 months were found to be independent risk factors. Knowing the risk factors for community acquired/onset urinary tract infections caused by ESBL-positive E. coli or K. pneumoniae is of great importance in planning empirical antibiotic therapy.
authors.affiliation: Dept. of Microbiology and Infectious Diseases, Uludag Univ., Bursa, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Yilmaz
authors.forename: H
authors.initials: H
authors.lastname: Akalin
authors.forename: S
authors.initials: S
authors.lastname: Ozbey
authors.forename: Y
authors.initials: Y
authors.lastname: Kordan
authors.forename: M
authors.initials: M
authors.lastname: Sinirtaş
authors.forename: E
authors.initials: E
authors.lastname: Gürcüoglu
authors.forename: C
authors.initials: C
authors.lastname: Ozakin
authors.forename: Y
authors.initials: Y
authors.lastname: Heper
authors.forename: R
authors.initials: R
authors.lastname: Mistik
authors.forename: S
authors.initials: S
authors.lastname: Helvaci
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D017714:Community-Acquired Infections; D004926:Escherichia coli; D004927:Escherichia coli Infections / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy*; D007711:Klebsiella pneumoniae; D008297:Male; D008875:Middle Aged; D015363:Quinolones / Q000627:therapeutic use; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000209:etiology* / Q000382:microbiology*; D013520:Urologic Surgical Procedures; D001618:beta-Lactamases
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D015363:Quinolones; D001618:beta-Lactamases