Intrapancreatic schwannoma diagnosed by endoscopic ultrasound-guided fine-needle aspiration cytology.
Schwannoma is a tumor of neuro-ectodermal origin, usually occuring in the head and neck and extremities. A retroperitoneal, and particularly intra-pancreatic presentation is very rare, and poses a clinical and diagnostic challenge. We report a case of a male patient who underwent an Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) biopsy of a hypoechoic, intra-pancreatic mass. The onsite cytological evaluation was consistent with a spindle cell neoplasm. Further evaluation, aided by immunohistochemical stains, defined the mass as a Schwannoma. The patient then underwent a pancreaticoduodenectomy and the histopathological diagnosis of the surgical specimen confirmed the cytological diagnosis. To our knowledge, this is the first report of intra-pancreatic Schwannoma diagnosed preoperatively by EUS-FNA cytology.
Li
Shaoying
S
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ai
Syed Z
SZ
Owens
Christopher
C
Kulesza
Peter
P
D000328:Adult; D044963:Biopsy, Fine-Needle / Q000379:methods; D024141:Collagen Type IV / Q000378:metabolism; D004724:Endoscopy; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D014463:Ultrasonography
D024141:Collagen Type IV; D009418:S100 Proteins; D019009:Proto-Oncogene Proteins c-kit