Kinetic tremor and cerebellar ataxia as initial manifestations of Kikuchi-Fujimoto's disease.
Involvement of central nervous system occasionally occurs as a form of aseptic meningitis in Kikuchi-Fujimoto disease (KFD). However, acute cerebellar symptoms are very rare in KFD. We describe a 42 year-old woman presenting kinetic tremor and gait ataxia preceding cervical lymphadenopathy. The diagnosis of KFD was made based on pathology. Lymphocyte-dominant pleocytosis was observed in cerebrospinal fluid. Brain and spinal magnetic resonance imaging showed no structural abnormalities. Acute cerebellar symptoms and cervical lymphadenopathy disappeared spontaneously within 2 months. This case of KFD involved unusual acute cerebellar symptoms. Selective involvement of the cerebellar system by viral or immunologic response may be attributed to acute cerebellar symptoms in KFD.
Moon
Ju-Sun
JS
Department of Neurology, Pochon CHA University college of medicine, South Korea.
Il Kim
Gwang
G
Koo
Young-Ho
YH
Kim
Hyun-Sook
HS
Kim
Won-Chan
WC
Kim
Ok-Joon
OJ
Oh
Seung-Hun
SH
D000328:Adult; D001706:Biopsy; D002524:Cerebellar Ataxia / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009483:Neuropsychological Tests; D014057:Tomography, X-Ray Computed; D014202:Tremor / Q000175:diagnosis* / Q000209:etiology