Inhibition of chymotrypsin by a self-assembled DNA quadruplex functionalized with cyclic peptide binding fragments.
Cai
Jianfeng
J
Department of Chemistry, Yale University, 225 Prospect Street, New Haven, CT 06511, USA.
Rosenzweig
Brooke A
BA
Hamilton
Andrew D
AD
D001483:Base Sequence; D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D054856:G-Quadruplexes; D010456:Peptides, Cyclic / Q000378:metabolism*
D004791:Enzyme Inhibitors; D010456:Peptides, Cyclic; D004247:DNA; D002918:Chymotrypsin