The doping effect of fluorinated aromatic hydrocarbon solvents on the performance of common olefin metathesis catalysts: application in the preparation of biologically active compounds.
Aromatic fluorinated hydrocarbons, used as solvents for olefin metathesis reactions, catalysed by standard commercially available Ru precatalysts, allow substantially higher yields to be obtained, especially of challenging substrates, including natural and biologically active compounds.
Samojłowicz
Cezary
C
Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Bieniek
Michał
M
Zarecki
Andrzej
A
Kadyrov
Renat
R
Grela
Karol
K
D000475:Alkenes / Q000737:chemistry*; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry; D001695:Biology; D002384:Catalysis; D017611:Fluorine Compounds / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry*
D000475:Alkenes; D001688:Biological Products; D017611:Fluorine Compounds; D006841:Hydrocarbons, Aromatic; D012997:Solvents