Magnetic nanoparticles for drug delivery applications.
In recent past magnetic nanoparticles have been explored for a number of biomedical applications due to their superparamagnetic moment with high magnetic saturation value. For these biomedical applications, magnetic nanoparticles require being monodispersed so that the individual nanoparticle has almost identical physico-chemical properties for biodistribution, bioelimination and contrast imaging potential. Further, the surface functionalization/modification of magnetic nanoparticles ultimately facilitate the protein or DNA separation, detection and magnetic resonance imaging contrast, drug delivery and hyperthermia applications. The essential goal of this review is to evaluate the recent advances of magnetic nanoparticles for tumor, brain targeting and hyperthermia applications.
Namdeo
Mini
M
Polymer Research Lab, Department of Chemistry, Government Model Science College, Jabalpur, MP 482001, India.
Saxena
Sutanjay
S
Tankhiwale
Rasika
R
Bajpai
M
M
Mohan
Y M
YM
Bajpai
S K
SK
D000818:Animals; D016503:Drug Delivery Systems / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D006979:Hyperthermia, Induced; D008280:Magnetics; D051379:Mice; D008956:Models, Chemical; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy*; D051381:Rats