title: [Acute Q fever, antiphopholipid antibodies and renal artery thrombosis: case report and literature review].
abstract: BACKGROUND
  Antiphospholipid antibodies (aPL) can be associated with numerous infectious and particularly Q fever. Data on the pathogenicity of aPL in the course of acute Q fever are scarce.
  
  
  METHODS
  We report the case an acute Coxiella burnetii infection associated with clinical and biological manifestations of the aPL syndrome, including a renal infarction. Along with antibiotic treatment, anticoagulation and intravenous immunoglobulins, the clinical outcome was favourable. Antiphospholipid antibodies and Q fever antibody titers had a closely related evolution.
  
  
  CONCLUSIONS
  Arterial thrombosis associated with Q fever and aPL is exceptional. The nosology and potential mechanisms are discussed.
authors.affiliation: Département de médecine interne, Centre hospitalier de Béziers, 34525 Béziers cedex, France.
authors.forename: Y-M
authors.initials: YM
authors.lastname: Pers
authors.forename: M
authors.initials: M
authors.lastname: Puygrenier
authors.forename: F
authors.initials: F
authors.lastname: Borlot
authors.forename: B
authors.initials: B
authors.lastname: Simorre
authors.forename: I
authors.initials: I
authors.lastname: Barazer
authors.forename: E
authors.initials: E
authors.lastname: Oziol
authors.forename: J-L
authors.initials: JL
authors.lastname: Reny
mesh_terms: D000208:Acute Disease; D000328:Adult; D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D011778:Q Fever / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012078:Renal Artery Obstruction / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants; D016756:Immunoglobulins, Intravenous