title: [Preservation of women fertility facing potential premature ovarian failure].
abstract: Numerous pathologies and their treatments may alter ovarian reserve in women and girls and may harm their future fertility. Oocytes cryopreservation techniques may be used in a limited number of cases, excluding young patients. We hereby report results obtained with our and other teams' ovarian tissue vitrification techniques. This new approach can be offered to young patients before puberty and should not delay both chemotherapy and radiotherapy when needed. Major drawbacks include potential alteration of ovarian reserve, as well as recurrence of the original malignancy. The later can be circumvented using in vitro maturation techniques. It is important to discuss fertility preservation opportunities with every woman or girls facing potential premature ovarian failure.
authors.affiliation: Département de gynécologie et d'obstétrique, HUG, Genève. anis.feki@hcuge.ch
authors.forename: Anis
authors.initials: A
authors.lastname: Feki
authors.forename: Timothée
authors.initials: T
authors.lastname: Fraisse
authors.forename: Olivier
authors.initials: O
authors.lastname: Irion
authors.forename: Jean-Bernard
authors.initials: JB
authors.lastname: Dubuisson
authors.forename: Outi
authors.initials: O
authors.lastname: Hovatta
mesh_terms: D000328:Adult; D015925:Cryopreservation / Q000379:methods; D003451:Cryoprotective Agents / Q000627:therapeutic use; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009865:Oocytes; D009924:Organ Culture Techniques; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D010053:Ovary; D016649:Primary Ovarian Insufficiency / Q000628:therapy*; D027724:Reproductive Techniques, Assisted; D055815:Young Adult
chemical_list: D003451:Cryoprotective Agents