title: Seroprevalence of human T lymphtropic virus (HTLV) among tissue donors in Iranian tissue bank.
abstract: Iranian Tissue Bank prepares a wide range of human tissue homografts such as; heart valve, bone, skin, amniotic membrane and other tissues for different clinical applications. The purpose of this study was to determine the seroprevalence of HTLV in tissue donors. About 1,548 tissue donors were studied during a 5-years period by ELISA assays. HTLV(1,2)-antibodies were tested for all of donors with other tests upon American Association of Tissue Banks (AATB) standards. About 25 (1.61%) out of 1,548 tissue donors were HTLV positive that 17 donors were male and 8 were female (female/male ratio was approximately 47%). Regarding to the prevalence of HTLV among tissue donors and importance of cell and tissue safety and quality assurance, we recommend that all blood, cell and tissue banks should be involved both routine serological methods and other complementary tests such as polymerase chain reaction (PCR) for diagnosis of HTLV.
authors.affiliation: Iranian Tissue Bank Research and Preparation Center & Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Imam Khomeini Hospital, Keshavarz Blvd., Tehran, Iran. arjmand_itb@yahoo.com
authors.forename: Babak
authors.initials: B
authors.lastname: Arjmand
authors.forename: Seyed Hamidreza
authors.initials: SH
authors.lastname: Aghayan
authors.forename: Parisa
authors.initials: P
authors.lastname: Goodarzi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Farzanehkhah
authors.forename: Seyed Mohamadjavad
authors.initials: SM
authors.lastname: Mortazavi
authors.forename: Mohamad Hossein
authors.initials: MH
authors.lastname: Niknam
authors.forename: Ali
authors.initials: A
authors.lastname: Jafarian
authors.forename: Farzin
authors.initials: F
authors.lastname: Arjmand
authors.forename: Soheyla
authors.initials: S
authors.lastname: Jebelly far
mesh_terms: D000328:Adult; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood*; D015482:HTLV-II Antibodies / Q000097:blood*; D015368:Human T-lymphotropic virus 1 / Q000276:immunology / Q000302:isolation & purification*; D015367:Human T-lymphotropic virus 2 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D014015:Tissue Banks / Q000592:standards*; D014019:Tissue Donors
chemical_list: D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies