Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis.
Multiple lymphomatous polyposis (MLP) is an unusual form of non-Hodgkin's lymphoma characterized by polyps throughout the gastrointestinal tract. It has been reported that most MLP are observed in cases with mantle cell lymphoma of B-cell type. We herein present a case of a 66-year-old man with adult T-cell leukemia/lymphoma (ATLL). Colonoscopy revealed MLP throughout the colon and histopathological findings of ATLL cell infiltration. The patient died despite combination of chemotherapy. The literature of manifestations of colonic involvement of ATLL is reviewed and the importance of endoscopic evaluation to differentiate ATLL intestinal lesions from opportunistic infectious enterocolitis is discussed.
Hokama
Akira
A
Department of Medicine and Therapeutics (First Department of Internal Medicine), Control and Prevention of Infectious Disease, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan. hokama-a@med.u-ryukyu.ac.jp
Tomoyose
Takeaki
T
Yamamoto
Yu
Y
Watanabe
Takako
T
Hirata
Tetsuo
T
Kinjo
Fukunori
F
Kato
Seiya
S
Ohshima
Koichi
K
Uezato
Hiroshi
H
Takasu
Nobuyuki
N
Fujita
Jiro
J
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D003111:Colonic Polyps / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003113:Colonoscopy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D044483:Intestinal Polyposis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017211:Treatment Failure