Pilot study assessing HIV vaccine trial readiness among female sex workers, injection and non-injection drug users, and men who have sex with men in Spain.
The purpose of this study was to assess HIV risk and willingness to participate in HIV vaccine trials in three high risk populations in Spain. Eight hundred and forty-four participants, comprising female sex workers, injection and non-injection drug users (IDUs and NIDUs, respectively), and men who have sex with men were tested for HIV and surveyed for risk and willingness to participate in future preventive HIV vaccine trials. HIV seroprevalence was 3.8% (95% CI: 2-11). HIV infection was associated with transgender identification, IDU in the past year, and sex with an IDU or other drug-using partner. The majority (82%) expressed their willingness to participate in HIV vaccine trials. Substantial sexual and parenteral risk in all groups and concomitant willingness to participate in vaccine trials was found, particularly among women and IDUs. Additional longitudinal cohort studies in Spain are needed to plan future vaccine efficacy trials.
Etcheverry
María Florencia
MF
AIDS Research Unit, Infectious Diseases Department, Hospital Clínic/IDIBAPS, School of Medicine, University of Barcelona, C/ Villarroel, 170, 08036, Barcelona, Spain.
de Lazzari
Elisa
E
Fuchs
Jonathan D
JD
Meroño
Mercé
M
Sierra
Ernesto
E
Del Romero
Jorge
J
Evans
Jennifer L
JL
Mendez-Arancibia
Eva
E
Jacques
Constanza
C
Rojas
Daniela
D
Segú
Marta
M
Gatell
José María
JM
Joseph
Joan
J
D016915:AIDS Vaccines / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic / Q000523:psychology*; D055030:Drug Users / Q000523:psychology; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D018451:Homosexuality, Male / Q000523:psychology; D006801:Humans; D008297:Male; D010358:Patient Participation / Q000523:psychology*; D010865:Pilot Projects; D011477:Sex Work / Q000523:psychology; D013030:Spain; D011795:Surveys and Questionnaires; D055815:Young Adult
D016915:AIDS Vaccines