[Clinical features of pulmonary disease caused by Mycobacterium fortuitum].
We analyzed clinical and microbiological features of six cases involving Mycobacterium fortuitum isolated from sputum or surgical lung specimen. Patients were five men and one woman with an average age of 59. Four cases had a history of pulmonary tuberculosis and three had nontuberculous mycobacterial lung disease. Three out of six cases had underlying chronic obstructive pulmonary disease. Diabetes mellitus was complicated in five cases. All diseases were in the upper lobes of either lung. Clinical symptoms were mainly cough and sputum, while two cases developed pneumothorax. Although all strains showed low sensitivity to standard anti-tuberculous agents, chemotherapy including those drugs or fluoroquinolones and macrolides were successful in all treated cases.
Hagiwara
Eri
E
Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center.
Sekine
Akimasa
A
Sato
Tomohide
T
Baba
Tomohisa
T
Shinohara
Takeshi
T
Endo
Takahiro
T
Sogo
Yoko
Y
Nishihira
Ryuichi
R
Komatsu
Shigeru
S
Matsumoto
Yutaka
Y
Ogura
Takashi
T
Takahashi
Hiroshi
H
D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000382:microbiology*; D019907:Mycobacterium fortuitum / Q000187:drug effects / Q000302:isolation & purification*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000382:microbiology*
D000995:Antitubercular Agents