title: [Clinical characteristics of methicillin-resistant Staphylococcus aureus in phlegm specimens].
abstract: OBJECTIVE
  To investigate the clinical characteristics of methicillin-resistant Staphylococcus aureus (MRSA) in phlegm specimens of positive patients, so as to provide evidences for the nosocomial infection control.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 211 hospitalized patients who were MRSA-positive in their phlegm specimens in PUMC Hospital from January 2005 to October 2007.
  
  
  RESULTS
  Among the 211 patients, 196 (92.9%) had received antibiotics three months before the detection of MRSA, and 128 (60.7%) had received more than three antibiotics. Over 90% of MRSA were resistant to levofloxacin, erythromycin, clindamycin, and gentamicin, and 73.9% were resistant to rifampicin.
  
  
  CONCLUSIONS
  Improper use of antibiotics should be avoided. Vancomycin is the first choice for MRSA treatment.
authors.affiliation: Hospital-acquired Infection Control Office, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Gui-Ping
authors.initials: GP
authors.lastname: Li
authors.forename: Jiong
authors.initials: J
authors.lastname: Zhou
authors.forename: Ai
authors.initials: A
authors.lastname: Wang
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Sun
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Ma
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000382:microbiology*; D012189:Retrospective Studies; D013183:Sputum / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents