Gene polymorphisms predisposing to cardiac hypertrophy in patients with cardiac syndrome X.
Polymorphisms of the angiotensin-converting enzyme gene and endothelial nitric oxide synthase gene have been suggested to be associated with left ventricular hypertrophy. The aim of our study was to asses the association between above polymorphisms and left ventricular hypertrophy in patients with cardiac syndrome X. The presence of allele 4 of eNOS VNTR polymorphism could predispose to cardiac hypertrophy. The pathological course of postprandial lipemia in patients with CSX may add to the understanding of the CSX pathology.
Jabrocka-Hybel
Agata
A
Colegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
Kolasińska-Kloch
Władysława
W
Malczewska-Malec
Małgorzata
M
Kieć-Wilk
Beata
B
Kwaśniak
Małgorzata
M
Kloch
Małgorzata
M
Dembińska-Kieć
Aldona
A
D006332:Cardiomegaly / Q000150:complications / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D017566:Microvascular Angina / Q000150:complications / Q000235:genetics*; D008875:Middle Aged; D052250:Nitric Oxide Synthase Type III / Q000235:genetics*; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic
D052250:Nitric Oxide Synthase Type III; D007703:Peptidyl-Dipeptidase A