title: Diagnostic evaluation of patients presenting with bleeding per rectum by colonoscopy.
abstract: BACKGROUND
  Rectal bleeding is a manifestation of lower gastrointestinal bleed, which means bleeding from a site distal to ligament of Treitz. Annual incidence of this problem has been estimated to be 20% and mortality as 11%. Patients complaining of haematochezia are suspected of having lower GI bleeding and proctosigmoidoscopy followed by colonoscopy is the examination of choice for diagnosis and treatment. Previous evidence suggested that in our country, frequencies of different aetiologies of lower GI bleed are different from the West. This study validated the previous findings. The Objective of this study was to determine the causes of rectal bleeding in adult patients at Military Hospital, Rawalpindi.
  
  
  METHODS
  One hundred and five adult patients with visible rectal bleed, irrespective of their gender were selected by non-probability convenient sampling from general medical OPD and general medical wards. Patients with suspected upper GI source of bleeding; haemorrhoidal bleed and acute infectious diarrhoea were excluded from the study. All patients were subjected to fibre-optic colonoscopy after necessary preparation and findings were recorded. Biopsies taken from suspected lesions were clinically indicated. Diagnosis was based on colonoscopic and histopathologic findings.
  
  
  RESULTS
  A total of 105 patients (77 male and 28 female) with mean age 41.04 yrs were part of the study. Colonoscopy showed abnormal findings in 85 (84%) patients. The commonest diagnosis was ulcerative colitis, which was found in 48 (46%) patients. It was followed by colorectal carcinoma, 11 (10%) patients, and non-specific colitis, 9 (8%) patients. Other less frequent findings were colonic diverticuli, 7 (6%) patients, solitary rectal ulcer, 5 (4%) patients, colonic polyps in 3 (2.5%) patients and one case each of telangiectasia and Crohn's disease.
  
  
  CONCLUSIONS
  Colonoscopy has very high diagnostic yield and would be recommended in the workup of patients presenting with bleeding per rectum. Ulcerative colitis was the leading cause of bleeding per rectum in this study; while infrequent findings of Crohn's disease, polyps and diverticuli indicate that these are uncommon in this region.
authors.affiliation: Department of Gastroenterolgy, Military Hospital, Rawalpindi. docznadeem@yahoo.com
authors.forename: Nadeem
authors.initials: N
authors.lastname: Zia
authors.forename: Tassawar
authors.initials: T
authors.lastname: Hussain
authors.forename: Amjad
authors.initials: A
authors.lastname: Salamat
authors.forename: Shakeel
authors.initials: S
authors.lastname: Mirza
authors.forename: Fayyaz
authors.initials: F
authors.lastname: Hassan
authors.forename: Ayesha
authors.initials: A
authors.lastname: Waqar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003113:Colonoscopy; D003430:Cross-Sectional Studies; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D041741:Lower Gastrointestinal Tract / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012812:Sigmoidoscopy; D055815:Young Adult