[Application of fallopian tube embolization before in vitro fertilization and embryo transfer dealing with the hydrosalpinx].
OBJECTIVE
To explore the effectiveness of the fallopian tubes embolization for the hydrosalpinx before in vitro fertilization and embryo transfer (IVF-ET).


METHODS
The fallopian tubes embolization was performed on 46 hydrosalpinx patients. First, the hysterosalpingography was performed to show the positions and shape of the hydrosalpinx. Then the hydrops was drawn into the celiac cavity in order to be absorbed after performing fallopian tube recanalization. Finally, transvaginal therapy was performed, putting the embolization microcoils into the fallopian tube through a micro-catheter One month after the fallopian tubes embolization, hysterosalpingography was conducted to check for the effectiveness of the embolization. After 3 months, all the 46 patients received the treatment of IVF-ET.


RESULTS
The interventional treatment of 82 fallopian tubes obtained one time success among 46 cases of fallopian tubes embolization. Among them, obvious results were achieved in 72 fallopian tubes, taking up 88% of the total; effective results were seen in 10 fallopian tubes, accounting for 12% of the total. No one was invalid. In the same period, compared with the 91 cases of non-hydrosalpinx as the control group, the embolization group of patients achieved a higher fertilization rate (69%), and clinical pregnancy rate (41%), compared with the control group (63% and 39% respectively), but without a significant difference ( P>0.05). However, the ectopic pregnancy rate (0) and the abortion rate (8%) were significantly lower than the control group (8%, 16% respectively; P<0.05).


CONCLUSIONS
Fallopian tubes embolization used in hydrosalpinx treatment before IVF-ET is an innovative approach, simple, safe, economical, with no negative impact on ovarian function. It can significantly increase the clinical pregnancy rate and prevent the occurrence of tubal pregnancy. It is a feasible and effective method.
Li
Qiang
Q
Department of Gynecology Intervention, Shanghai Pudong New Area Health Care Hospital for Women and Children, Shanghai 201206, China. liqiang1110@sina.com
Kuang
Yan-ping
YP
Yang
Hui-lin
HL
Fu
Yong-lun
YL
Sun
Hong
H
Fan
Li-ping
LP
Shi
Hai-bin
HB
D000328:Adult; D004621:Embolization, Therapeutic; D004624:Embryo Transfer; D005184:Fallopian Tube Diseases / Q000150:complications / Q000628:therapy*; D005187:Fallopian Tubes / Q000473:pathology / Q000601:surgery; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies