title: [HIV-related multiple non-Hodgkin lymphomas].
abstract: A 35-year-old man was admitted with continuous general fatigue and low grade fever. He was HIV-positive, and had gastric diffuse large B-cell lymphoma and renal T-cell anaplastic large cell lymphoma (T-ALCL). We diagnosed double lymphomas related to AIDS. The patient received anti-retroviral therapy, and started the CHOP regimen for the double lymphomas, resulting in transient improvement. However, fever again appeared during HAART and CHOP treatment, and a right inguinal subcutaneous lesion appeared. Biopsy specimen demonstrated null cell ALCL, and this patient demonstrated multiple lymphomas. This case suggested that cancer generation was promoted by low immunity, although it is known that ambivalent tumors such as non-Hodgkin lymphomas can occur frequently.
authors.affiliation: First Department of Internal Medicine, Tokyo Medical University.
authors.forename: Moritaka
authors.initials: M
authors.lastname: Gotoh
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Kitahara
authors.forename: Tomotaka
authors.initials: T
authors.lastname: Iguchi
authors.forename: Miki
authors.initials: M
authors.lastname: Izumi
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Mukai
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ohyashiki
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D008215:Lymphocytes, Null; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis* / Q000188:drug therapy; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009378:Neoplasms, Multiple Primary; D011239:Prednisolone / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone