title: Carcinosarcoma of the uterus: a case report and review of the literature.
abstract: Carcinosarcoma is a rare tumor of the uterus with a poor prognosis. We present a case of uterine carcinosarcoma in an 82-year-old woman who suffered from pervaginal bleeding for ten months duration with progressive anemia. Abdominopelvic nuclear magnetic resonance (NMR) imaging showed the presence of an intrauterine mass, infiltrating the myometrium and reaching the cervix. The patient was submitted to total abdominal hysterectomy with bilateral salpingo-oophorectomy. The carcinosarcoma, arising from the lumen of the uterus, infiltrated the inner one-third of the myometrial layer (pT1b, pNx, pMx; FIGO Stage 1B). A CT of the total body performed six months after surgery showed no signs of recurrent and/or metastatic tumor. The clinicopathological features, treatment options and prognosis of this aggressive neoplasm are reviewed.
authors.affiliation: Medicine and Surgery, A. Fiorini Hospital, University of Rome La Sapienza, Polo Pontino, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Spaziani
authors.forename: M
authors.initials: M
authors.lastname: Picchio
authors.forename: V
authors.initials: V
authors.lastname: Petrozza
authors.forename: M
authors.initials: M
authors.lastname: Briganti
authors.forename: F
authors.initials: F
authors.lastname: Ceci
authors.forename: A
authors.initials: A
authors.lastname: Di Filippo
authors.forename: B
authors.initials: B
authors.lastname: Sardella
authors.forename: F
authors.initials: F
authors.lastname: De Angelis
authors.forename: C
authors.initials: C
authors.lastname: Della Rocca
authors.forename: F
authors.initials: F
authors.lastname: Stagnitti
mesh_terms: D000369:Aged, 80 and over; D002296:Carcinosarcoma / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D014594:Uterine Neoplasms / Q000473:pathology* / Q000628:therapy