Hydrogen transfer reduction of polyketones catalyzed by iridium complexes: a novel route towards more biocompatible materials.
Transfer hydrogenation from 2-propanol to CO/4-methylstyrene and CO/styrene polyketones was catalyzed by [Ir(diene)(N-N)X] (N-N = nitrogen chelating ligand; X = halogen) in the presence of a basic cocatalyst. The reactions were performed using dioxane as cosolvent, in order to overcome problems due to low polyketone solubility. The polyalcohols were obtained in yields up to 95%, the conversions being markedly dependent on the nature of the ligands coordinated to iridium as well as on the experimental conditions.
Milani
Barbara
B
Dipartimento di Scienze Chimiche, Università di Trieste, Via Giorgieri 1, 34127, Trieste, Italy.
Crottib
Corrado
C
Farnetti
Erica
E
D000098:Acetophenones / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D001894:Borohydrides; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D018020:Lithium Compounds; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D013343:Styrenes / Q000737:chemistry
D000098:Acetophenones; D001672:Biocompatible Materials; D001894:Borohydrides; D007659:Ketones; D018020:Lithium Compounds; D009942:Organometallic Compounds; D013343:Styrenes; D007495:Iridium; D006859:Hydrogen; C040936:lithium borohydride