Therapeutic and predictive targets of AKI.
Acute kidney injury (AKI) is a very common condition encountered in a hospital setting. AKI is an independent risk factor for in-hospital mortality. In this review, we discuss in detail about the tubular, inflammatory and vascular molecular targets of AKI which may result in therapies to improve mortality and biomarkers for earlier diagnosis of AKI.
Yalavarthy
R
R
Department of Kidney Diseases, University of Colorado at Denver and Health Sciences Center, Denver, CO 80045, USA.
Edelstein
C L
CL
D058186:Acute Kidney Injury / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D000209:Acute-Phase Proteins / Q000378:metabolism; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D018925:Chemokines / Q000378:metabolism; D003937:Diagnosis, Differential; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D015994:Incidence; D007684:Kidney Tubules / Q000378:metabolism; D015995:Prevalence; D011379:Prognosis; D017582:Renal Replacement Therapy / Q000379:methods*
D000209:Acute-Phase Proteins; D015415:Biomarkers; D018925:Chemokines