Titanocene(III) chloride-mediated reductions of oxazines, hydroxamic acids, and N-hydroxy carbamates.
Titanocene(III) chloride (Cp(2)TiCl), generated in situ, reduces N-O bonds of various substrates in good to excellent yields (72-95%). Reactions may be performed with stoichiometric Cp(2)TiCl or with catalytic Cp(2)TiCl.
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Cara
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Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46545, USA.
Tardibono
Lawrence P
LP
Miller
Marvin J
MJ
D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D006877:Hydroxamic Acids / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010078:Oxazines / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D002219:Carbamates; D002712:Chlorides; D006877:Hydroxamic Acids; D009942:Organometallic Compounds; D010078:Oxazines; C406884:titanocene