title: Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter.
abstract: OBJECTIVE
  The aim of this study was to determine if warming patients prior to and during (18)F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).
  
  
  METHODS
  A group of 40 children underwent (18)F-FDG PET after being kept in the injection room at a constant temperature of 24 degrees C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21 degrees C.
  
  
  RESULTS
  Uptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21 degrees C (p<0.002).
  
  
  CONCLUSIONS
  Maintaining room temperature at a constant 24 degrees C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.
authors.affiliation: Department of Radiology, Division of Nuclear Medicine/PET, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Zukotynski
authors.forename: Frederic H
authors.initials: FH
authors.lastname: Fahey
authors.forename: Stephen
authors.initials: S
authors.lastname: Laffin
authors.forename: Royal
authors.initials: R
authors.lastname: Davis
authors.forename: S Ted
authors.initials: ST
authors.lastname: Treves
authors.forename: Frederick D
authors.initials: FD
authors.lastname: Grant
authors.forename: Laura A
authors.initials: LA
authors.lastname: Drubach
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000494:pharmacology*; D012189:Retrospective Studies; D012621:Seasons; D013696:Temperature
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18