Pre-therapy hyperfunctioning follicular thyroid carcinoma evaluation with I-131 whole-body scan and with F-18 FDG PET/CT.
We describe a patient with persistent hyperthyroidism after total thyroidectomy for toxic multinodular goiter and without therapy with levothyroxine evaluated with I-131 whole-body scan and with F-18 FDG PET/CT scan. Scintigraphy performed 48 hours after radiopharmaceutical administration showed many areas of focal radioiodine uptake. A week later we performed a PET/CT scan to better localize the anatomic site of the iodine-positive lesions. Both scans, performed after methimazole withdrawal, visualized the same lesions, and these results were used as a guide for biopsy. Histologic examination was consistent with metastatic follicular thyroid carcinoma.
Orsolon
Piergiuseppe
P
Servizio di Medicina Nucleare, Ospedale Civile San Bortolo, Vicenza, Italy. porsolon@virgilio.it
Giachetti
Marcello
M
Lupi
Andrea
A
Salgarello
Matteo
M
Malfatti
Veronica
V
Zanco
Pierluigi
P
D018263:Adenocarcinoma, Follicular / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D000368:Aged; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006019:Glycolysis; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D008297:Male; D049268:Positron-Emission Tomography; D013964:Thyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D007457:Iodine Radioisotopes; D019788:Fluorodeoxyglucose F18