title: [Granulocytic sarcoma of the prostate presenting with urinary obstruction which progressed to acute myeloid leukemia].
abstract: A 71-year-old man presented with progressive dysuria. Several imaging examinations indicated possibility of prostate tumor, therefore he underwent prostate biopsy. This resulted in a diagnosis of granulocytic sarcoma of the prostate. Since bone marrow appeared normal on aspiration biopsy, he was treated with local irradiation. Prostate swelling then markedly diminished and his symptoms disappeared. However, four months later he progressed to AML. He then received systemic chemotherapy and achieved complete remission. We discuss the management of granulocytic sarcoma when findings do not indicate overt leukemia at the time of diagnosis.
authors.affiliation: Division of Hematology/Oncology, Department of Medicine, Tokai University School of Medicine.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Tsuboi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kawada
authors.forename: Rikio
authors.initials: R
authors.lastname: Suzuki
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Murayama
authors.forename: Ken
authors.initials: K
authors.lastname: Ohmachi
authors.forename: Naoya
authors.initials: N
authors.lastname: Nakamura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Ando
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage; D018450:Disease Progression; D053159:Dysuria / Q000209:etiology*; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D016609:Neoplasms, Second Primary; D011471:Prostatic Neoplasms / Q000150:complications* / Q000532:radiotherapy; D012074:Remission Induction; D023981:Sarcoma, Myeloid / Q000150:complications* / Q000532:radiotherapy
chemical_list: D003561:Cytarabine; D015255:Idarubicin