title: Midterm survival of a contemporary modular total knee replacement: a multicentre study of 1970 knees.
abstract: This retrospective study evaluated the midterm clinical and radiographic outcomes of a second-generation total knee replacement system. In a multicentre consecutive series of 1512 patients, 1970 knees were treated with the PFC Sigma knee system (Depuy, Warsaw, Indiana). The patients were reviewed for functional outcome, and underwent independent radiographic evaluation at a mean follow-up of 7.3 years (5 to 10). A total of 40 knees (2%) required revision, 17 (0.9%) for infection. The incidence of osteolysis was 2.2%. The ten-year survival with revision for any cause other than infection as the endpoint was 97.2% (95% CI 95.4 to 99.1). The PFC Sigma knee system appears to provide excellent results in the medium term.
authors.affiliation: St. Joseph Medical Center, 8322 Bellona Avenue, Baltimore, Maryland 21204, USA. ehenzel@jhmi.edu
authors.forename: D F
authors.initials: DF
authors.lastname: Dalury
authors.forename: W P
authors.initials: WP
authors.lastname: Barrett
authors.forename: J B
authors.initials: JB
authors.lastname: Mason
authors.forename: W M
authors.initials: WM
authors.lastname: Goldstein
authors.forename: J A
authors.initials: JA
authors.lastname: Murphy
authors.forename: M W
authors.initials: MW
authors.lastname: Roche
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000592:standards*; D016001:Confidence Intervals; D019544:Equipment Failure Analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D007720:Knee Prosthesis / Q000592:standards*; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D010014:Osteolysis / Q000000981:diagnostic imaging*; D011474:Prosthesis Design; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging; D011859:Radiography; D016059:Range of Motion, Articular / Q000502:physiology*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome