title: Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis.
abstract: Multiple lymphomatous polyposis (MLP) is an unusual form of non-Hodgkin's lymphoma characterized by polyps throughout the gastrointestinal tract. It has been reported that most MLP are observed in cases with mantle cell lymphoma of B-cell type. We herein present a case of a 66-year-old man with adult T-cell leukemia/lymphoma (ATLL). Colonoscopy revealed MLP throughout the colon and histopathological findings of ATLL cell infiltration. The patient died despite combination of chemotherapy. The literature of manifestations of colonic involvement of ATLL is reviewed and the importance of endoscopic evaluation to differentiate ATLL intestinal lesions from opportunistic infectious enterocolitis is discussed.
authors.affiliation: Department of Medicine and Therapeutics (First Department of Internal Medicine), Control and Prevention of Infectious Disease, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan. hokama-a@med.u-ryukyu.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Hokama
authors.forename: Takeaki
authors.initials: T
authors.lastname: Tomoyose
authors.forename: Yu
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Takako
authors.initials: T
authors.lastname: Watanabe
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Hirata
authors.forename: Fukunori
authors.initials: F
authors.lastname: Kinjo
authors.forename: Seiya
authors.initials: S
authors.lastname: Kato
authors.forename: Koichi
authors.initials: K
authors.lastname: Ohshima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Uezato
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takasu
authors.forename: Jiro
authors.initials: J
authors.lastname: Fujita
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D003111:Colonic Polyps / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003113:Colonoscopy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D044483:Intestinal Polyposis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017211:Treatment Failure