title: The history of vaccinations in the light of the autism epidemic.
abstract: Autism has been characterized as a behavioral disorder since it was first described by Leo Kanner in 1943. The number of autistic children has increased over the last decade. The incidence of autism was 1 in 10000 before the 1970s and has steadily increased to 1 in 150 in 2008 with a male:female predominance of 4:1. The cause of this epidemic has remained unknown, but several hypotheses have been studied. Many of these suggest an environmental trigger, such as the ethyl mercury contained in the preservative thimerosal, which has been used in vaccines since 1931. Other possible triggers associated with vaccinations are chemical toxins and live viruses. James has published studies suggesting a genetic predisposition in the families of autistic children, exposing them to a deficiency in glutathione and an inability to detoxify heavy metals. Vargas has shown autism to encompass ongoing inflammation in the brains of autistic children. The Hannah Poling vaccine decision was a landmark case. Poling's family was awarded funds for ongoing medical care of an autistic child who was found to have mitochondrial dysfunction exacerbated by vaccines that left her with autistic behavior and seizures. Several studies have emerged supporting the fact that a significant number of autistic children do have mitochondrial dysfunction. The impact that the Poling case will have on the ability of parents of autistic children to gain access to funds to enable them to properly care for their children remains to be seen.
authors.affiliation: Cypress Integrative Medicine, Baton Rouge, Louisiana, USA.
authors.forename: Stephanie F
authors.initials: SF
authors.lastname: Cave
mesh_terms: D001321:Autistic Disorder / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D002675:Child, Preschool; D004777:Environment; D005035:Ethylmercury Compounds / Q000009:adverse effects; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D028361:Mitochondrial Diseases / Q000150:complications*; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D014611:Vaccination / Q000009:adverse effects*
chemical_list: D005035:Ethylmercury Compounds; D011310:Preservatives, Pharmaceutical