title: Ion-pair hollow-fiber liquid-phase microextraction of the quaternary ammonium surfactant dicocodimethylammonium chloride.
abstract: A two-phase hollow-fiber (HF) liquid-phase microextraction (LPME) method was developed for determination of a quaternary ammonium compound surfactant, dicocodimethylammonium chloride, in aqueous samples. The porous HF was fixed on a metal rod support and was impregnated with approximately 6.6 microL of organic extractant, which was immobilized in the HF pores. Surfactant extraction was facilitated by addition of carboxylic acid to the sample forming neutral ion pairs with the quaternary ammonium compound. After extraction, the analyte was transferred from the organic extractant in the fiber pores by dissolving the 1-octanol into 100 microL methanol. The methanol extract was analyzed by liquid chromatography-mass spectrometry. The method was optimized (with optimized parameters in brackets) with regard to type of organic extractant (1-octanol), fiber length (2 cm), choice and concentration of anionic carrier (600 microg L(-1) octanoate), procedure of transfer to methanol (15-min sonication), sample volume (250 mL), extraction time (17 h), pH (10), and ionic strength (50 mM carbonate). Aspects influencing repeatability in LPME of (quaternary ammonium) surfactants are discussed. The enrichment factor achieved in 250-mL carbonate buffer was around 400. Due to matrix effects, the enrichment factors achieved when industrial process water was analyzed were 120 or about 30% of that in carbonate buffer. Detection limits of 0.3 microg L(-1) in carbonate buffer and 0.9 microg L(-1) in industrial process water were obtained. If the studied compound is seen as a model substance representing quaternary dialkylated dimethylated ammonium surfactants in general, the developed method may be applied to other quaternary ammonium surfactants.
authors.affiliation: AkzoNobel Surface Chemistry AB, 444 85, Stenungsund, Sweden.
authors.forename: Sofie
authors.initials: S
authors.lastname: Hultgren
authors.forename: Niklas
authors.initials: N
authors.lastname: Larsson
authors.forename: Bo F
authors.initials: BF
authors.lastname: Nilsson
authors.forename: Jan Ake
authors.initials: JA
authors.lastname: Jönsson
mesh_terms: D005591:Chemical Fractionation / Q000295:instrumentation* / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D006863:Hydrogen-Ion Concentration; D013058:Mass Spectrometry; D008567:Membranes, Artificial; D000644:Quaternary Ammonium Compounds / Q000302:isolation & purification*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012997:Solvents / Q000737:chemistry; D013501:Surface-Active Agents / Q000302:isolation & purification*; D013997:Time Factors
chemical_list: D008567:Membranes, Artificial; D000644:Quaternary Ammonium Compounds; D012997:Solvents; D013501:Surface-Active Agents