[Effect of Candida albicans growth on silicone elastomer containing nano-TiO2].
OBJECTIVE
To study the antibacterial effect against Candida albicans of the A-2186 silicone elastomer containing nano-TiO2 in vitro.


METHODS
Antibacterial agent of nano-TiO2 was added into A-2186 silicone elastomer with incorporating percentages of 0.5%, 1.0%, 1.5%, and 2.0% (W/W). There was no nano-TiO2 in the control group. The antibacterial effect of the A-2186 silicone elastomer was determined using the film contact method with lighting and without lighting.


RESULTS
Either with lighting or without lighting, there were significances between the experiment groups and the control group (P < 0.05). When the incorporating percent was 2.0%, the inhibitory effect was the best among the experiment groups. Without lighting, the inhibitory rate was 53.7% and with lighting, the inhibitory rate was 85.9%.


CONCLUSIONS
The A-2186 silicone elastomer containing nano-TiO2 has antibacterial properties against Candida albicans, which enhances with increases of nano-TiO2 percent in the material. With the same incorporating percentage, the antibacterial effect with lighting is better than that without lighting.
Li
Bei
B
Department of Prosthodontics, College of Stomatology, The Fourth Military Medical University, Xi'an, China.
Zhao
Yi-Min
YM
Yang
Ju-Cai
JC
Han
Ying
Y
Dong
Zhi-Wei
ZW
D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D049329:Nanostructures; D012826:Silicone Elastomers / Q000737:chemistry* / Q000494:pharmacology; D014025:Titanium / Q000494:pharmacology*
D000935:Antifungal Agents; D012826:Silicone Elastomers; C009495:titanium dioxide; D014025:Titanium