Synthesis, characterization, and antifungal activity of boron-containing thiosemicarbazones.
Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2-formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1-benzodiazaborines. All new compounds have been investigated for potential antifungal activity.
Hicks
Justin W
JW
Department of Chemistry, Mount Allison University, Sackville NB E4L1G8, Canada.
Kyle
Christian B
CB
Vogels
Christopher M
CM
Wheaton
Susan L
SL
Baerlocher
Felix J
FJ
Decken
Andreas
A
Westcott
Stephen A
SA
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D013882:Thiosemicarbazones