title: [Analgesia and renal insufficiency].
abstract: Chronic kidney disease (CKD) prevalence increases with population aging and makes drugs prescription more difficult. Only a few studies have reported drug dosing adjustment in CKD patients, even in the important field of pain management. We propose an algorithm based on the current literature that helps in selecting right analgesic according to the degree of renal failure. Drug dosing adjustment of the most usually used analgesics (acetaminophen, nonsteroidal anti-inflammatory drugs and opioids) is discussed.
authors.affiliation: Service de néphrologie, HUG, 1211 Genève 14. vincent.bourquin@hcuge.ch
authors.forename: Vincent
authors.initials: V
authors.lastname: Bourquin
authors.forename: Pierre-Auguste
authors.initials: PA
authors.lastname: Petignat
authors.forename: Marie
authors.initials: M
authors.lastname: Besson
authors.forename: Valérie
authors.initials: V
authors.lastname: Piguet
mesh_terms: D000465:Algorithms; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D051436:Renal Insufficiency, Chronic / Q000150:complications*
chemical_list: D000700:Analgesics