title: What is the quality of the evidence base for pre-implant surgery of the atrophic jaw?
abstract: This review aimed to evaluate the level of evidence for bone augmentation preimplant surgery for atrophic jaws in studies which measure outcome. Medline, Embase, Cochrane library and online journal searches were performed with a defined search strategy and the abstracts screened against selection criteria. The resultant papers were sorted by study design using the Cochrane study design algorithm, analysed for clinical/statistical homogeneity and graded with the Oxford Centre of Evidence-based Medicine levels of evidence. The initial online Medline search yielded 1194 results and the Embase search yielded 490 results. Using the selection criteria, 10 studies were identified. Additionally, 5 articles were identified from bibliography and online searches, giving a total of 15 studies for grading. All 15 studies were graded as level 4 evidence. No meta-analysis of outcomes was possible with the low level of evidence and degree of heterogeneity found. The best grade of recommendation that can be made for a particular preimplant surgical bone augmentation procedure, from these level 4 studies, is Grade C. Benchmarking studies by assessing quality of evidence can be helpful to inform future study designs with respect to reporting study outcomes with a higher level of evidence.
authors.affiliation: Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK.
authors.forename: T K
authors.initials: TK
authors.lastname: Blackburn
authors.forename: J I
authors.initials: JI
authors.lastname: Cawood
authors.forename: P J W
authors.initials: PJ
authors.lastname: Stoelinga
authors.forename: D
authors.initials: D
authors.lastname: Lowe
mesh_terms: D000540:Alveolar Ridge Augmentation; D001284:Atrophy; D015921:Dental Implants; D055094:Evidence-Based Dentistry / Q000592:standards*; D006801:Humans; D007568:Jaw / Q000473:pathology; D013516:Oral Surgical Procedures, Preprosthetic; D056948:Orthognathic Surgical Procedures; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants