High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica.
An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l(-1) at pH 3, produced 170 g erythritol l(-1) after 7 days, corresponding to a 56% yield and a productivity of 1 g l(-1) h(-1). The Wratislavia K1 strain did not produce citric acid.
Rymowicz
Waldemar
W
Department of Biotechnology and Food Microbiology, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375, Wroclaw, Poland. Waldemar.Rymowicz@wnoz.up.wroc.pl
Rywińska
Anita
A
Marcinkiewicz
Marta
M
D019343:Citric Acid / Q000378:metabolism; D004896:Erythritol / Q000096:biosynthesis*; D005990:Glycerol / Q000378:metabolism*; D013997:Time Factors; D025062:Yarrowia / Q000378:metabolism*
D019343:Citric Acid; D005990:Glycerol; D004896:Erythritol