title: Prevalence of cancer-associated viral infections in healthy afro-Caribbean populations: a review of the literature.
abstract: Cancer is one of the five leading causes of death in the Caribbean. Viral infections have been associated with cancer development and propagation, but the prevalence of such infections in the Caribbean is unknown. This review of the published literature shows that in 161,196 subjects from 14 Caribbean Islands, the adjusted prevalence of HHV8 infection is 4.5%, HTLV-1: 1.0%, HPV: 57.5%, HCV: 0.4%, HBV: 9.4%, and EBV: 92.2%. With the exception of HCV, the prevalence was significantly higher in the Caribbean than in the United States. These findings may significantly contribute to the high incidence of cancer observed in the Caribbean.
authors.affiliation: Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. ragincc@upmc.edu
authors.forename: C
authors.initials: C
authors.lastname: Ragin
authors.forename: R
authors.initials: R
authors.lastname: Edwards
authors.forename: D E
authors.initials: DE
authors.lastname: Heron
authors.forename: J
authors.initials: J
authors.lastname: Kuo
authors.forename: E
authors.initials: E
authors.lastname: Wentzel
authors.forename: S M
authors.initials: SM
authors.lastname: Gollin
authors.forename: E
authors.initials: E
authors.lastname: Taioli
mesh_terms: D044383:Black People; D017691:Caribbean Region / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000821:virology*; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014777:Virus Diseases / Q000150:complications*