title: Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure.
abstract: Patients, especially those with chronic disease and disorders are increasingly relying on complementary and alternative medical therapies (CAMT). Because the use of CAMT is escalating worldwide, it is essential to be aware of the clinical and adverse effects, doses and potential drug-herb interactions. Crataegus orientalis or hawthorn is a small tree with red fruits. A number of studies appear to demonstrate that Crataegus spp. have a clinically detectable positive cardiac inotropic action. The ingredients, characteristics of metabolism and elimination, and adverse effects of hawthorn remain largely unknown. We report a case of multisystem hypersensitivity reaction and progressive acute renal failure associated with the consumption of Crataegus orientalis.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, Mersin Universitiy, School of Medicine, Mersin, Turkey. mehmethoroz@yahoo.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Horoz
authors.forename: Ebru
authors.initials: E
authors.lastname: Gok
authors.forename: Gultekin
authors.initials: G
authors.lastname: Genctoy
authors.forename: Turkay
authors.initials: T
authors.lastname: Ozcan
authors.forename: Refik
authors.initials: R
authors.lastname: Olmaz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akca
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kiykim
authors.forename: Iclal
authors.initials: I
authors.lastname: Gurses
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis*; D000368:Aged; D027825:Crataegus / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008517:Phytotherapy / Q000009:adverse effects*; D018515:Plant Leaves / Q000009:adverse effects; D013662:Tea / Q000009:adverse effects
chemical_list: D013662:Tea