Reaction of benzyne with salicylaldehydes: general synthesis of xanthenes, xanthones, and xanthols.
The reaction of salicylaldehydes with benzyne prepared from o-trimethylsilyphenyl triflate and CsF gave xanthenes and xanthones. When the reaction was carried out under basic conditions, 9-hydroxyxanthenes (xanthols) were obtained in good yields.
Okuma
Kentaro
K
Department of Chemistry, Faculty of Science, Fukuoka University, Jonan-ku, Fukuoka 814-0180, Japan. kokuma@fukuoka-u.ac.jp
Nojima
Akiko
A
Matsunaga
Nahoko
N
Shioji
Kosei
K
D000447:Aldehydes / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014966:Xanthenes / Q000138:chemical synthesis* / Q000737:chemistry; D044004:Xanthones / Q000138:chemical synthesis* / Q000737:chemistry
D000447:Aldehydes; D001555:Benzene Derivatives; D014966:Xanthenes; D044004:Xanthones; C524146:benzyne