title: A TRP channel-steroid marriage.
abstract: A surprising functional association between TRPM3, a mysterious member of the family of transient receptor potential (TRP) cation channels, and the sulphated version of pregnenolone, 'mother' of all steroid hormones, has been identified.
authors.affiliation: Department of Molecular Cell Biology, Laboratory of Ion Channel Research, KU Leuven, Campus Gasthuisberg, Herestraat 49, bus 802, B-3000 Leuven, Belgium. bernd.nilius@med.kuleuven.be
authors.forename: Bernd
authors.initials: B
authors.lastname: Nilius
authors.forename: Thomas
authors.initials: T
authors.lastname: Voets
mesh_terms: D000818:Animals; D006801:Humans; D050417:Insulin-Secreting Cells / Q000187:drug effects / Q000378:metabolism; D015640:Ion Channel Gating / Q000187:drug effects; D051379:Mice; D011284:Pregnenolone / Q000494:pharmacology; D051381:Rats; D011987:Receptors, Steroid / Q000378:metabolism*; D050053:TRPM Cation Channels / Q000378:metabolism*
chemical_list: D011987:Receptors, Steroid; D050053:TRPM Cation Channels; C018370:pregnenolone sulfate; D011284:Pregnenolone