title: Impact of the linker groups in bis(7-azaindol-1-yl) chelate ligands on structures and stability of Pt(N,N-L)R(2) complexes.
abstract: New organoplatinum(II) complexes with the general formula of Pt(N,N-L)R(2), where L is a bis(7-azaindol-1-yl) chelate ligand, R is a methyl or a phenyl, have been synthesized and investigated with the aim to understand the impact of the linker group in the L ligand on the structure and the stability of the Pt(II) complexes. The L ligands used in our investigation belong to two classes: class I with an aliphatic linker between two 7-azaindolyl groups such as -CH(2)- (BAM), -(CH(2))(3)- (1,3-BAPr), and -(CH(2))(4)- (1,4-BABu), class II with an aromatic linker such as 1,2-phenyl (1,2-BAB) 1,3-phenyl (1,3-BAB) and 1,4-dihydronaphthalene-1,4-epoxide (BAHE). The structures of these new mononuclear Pt(II) complexes have been determined by single-crystal X-ray diffraction analyses. For the 1,3-BAPr ligand, a dinuclear complex with the formula of [Pt(SMe(2))Ph(2)](2)(1,3-BAPr) was also obtained and its structure was established by X-ray diffraction analysis. The linker group's impact on the N-Pt-N bite angle and the relative orientation of the two 7-azaindolyl rings was examined by using the crystal structural data. Intramolecular three-center four-electron Pt(II) ... H-C interactions have been established for all Pt(II) complexes with class I ligands by single-crystal X-ray diffraction and (1)H NMR spectroscopic analyses. Complexes Pt(1,3-BAPr)Me(2) and Pt(1,4-BABu)Me(2) have been found to have a poor stability, compared to the 1,2-BAB and BAM analogues. Two geometric isomers of the Pt(BAHE)Ph(2) complex have been identified by NMR spectra and the structure of one of the isomers has been determined by X-ray diffraction analysis, establishing that the BAHE ligand is most effective in blocking the 5th coordination site of the Pt(II) center.
authors.affiliation: Department of Chemistry, Queen's University, Kingston, Ontario, Canada.
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Zhao
authors.forename: Guo-hui
authors.initials: GH
authors.lastname: Liu
authors.forename: Datong
authors.initials: D
authors.lastname: Song
authors.forename: Suning
authors.initials: S
authors.lastname: Wang
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002073:Butanes / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000737:chemistry; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*
chemical_list: D001372:Aza Compounds; D002073:Butanes; D002614:Chelating Agents; D004852:Epoxy Compounds; D007211:Indoles; D008024:Ligands; D009942:Organometallic Compounds; D010984:Platinum; C046888:butane; C030374:indole