Herpes zoster and meningitis resulting from reactivation of varicella vaccine virus in an immunocompetent child.
Herpes zoster complicated by meningitis has been mainly reported in immunocompromised patients after reactivation of wild-type varicella-zoster virus. We present one of the first cases of aseptic meningitis after herpes zoster caused by reactivation of vaccine-type varicella-zoster virus in an immunocompetent child. We also highlight the increasing role of both wild-type and vaccine strains of varicella-zoster virus as a cause of viral meningoencephalitis and the use of appropriate laboratory tools to rapidly and accurately identify the virus in order to provide prompt patient care and management.
Iyer
Sujit
S
The Children's Hospital of Philadelphia, PA 19104-4399, USA. iyers@email.chop.edu
Mittal
Manoj K
MK
Hodinka
Richard L
RL
D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D002648:Child; D006562:Herpes Zoster / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008587:Meningitis, Viral / Q000188:drug therapy / Q000276:immunology*
D000998:Antiviral Agents; D019433:Chickenpox Vaccine; D000212:Acyclovir