[Study on the risk factors regarding deep venous thrombosis in acute pulmonary thromboembolism].
OBJECTIVE
To identify the risk factors of deep venous thrombosis(DVT) in patients with acute pulmonary thromboembolism (PTE).


METHODS
Post hoc analysis on data from a prospective multicenter through a randomized control trial on thrombolysis and anticoagulant among 454 patients with acute symptomatic PTE from June 2002 to December 2004. All patients were confirmed PTE by CT pulmonary angiography (CTPA) and/or ventilation perfusion scan or by magnetic resonance pulmonary angiography. Data of PTE patients with DVT was compared with those without DVT to identify the DVT risk factors. The effect of other variable on DVT was assessed by logistic regression analysis.


RESULTS
When comparing the age, sex body weight index and underlying diseases including hypertension, coronary heart disease, chronic obstructive pulmonary disease, cerebral accident and malignant tumor between groups of DVT and no DVT,data showed that there was no statistically significant difference except for diabetes (chi2 = 4.481, P = 0.034) among them.However,results from multi-analysis showed that edema of lower-limb [odd ratio (OR), 2.255; 95% CI, 1.493 to 3.408], phlebitis (OR, 2.380; 95% CI, 1.426 to 3.973) and the entire swollen (calf swelling > or =1 cm) larger than asymptomatic side (OR, 3.834; 95% CI, 2.561 to 5.738) were independent risk factors for DVT.


CONCLUSIONS
Edema of lower-limb, phlebitis and calf swelling > or =1 cm seemed to be risk factors for DVT.
Yang
Yuan-hua
YH
Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Guo
Xiao-juan
XJ
Zhai
Zhen-guo
ZG
Wang
Feng
F
Wang
Chen
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D004487:Edema; D005260:Female; D006801:Humans; D016015:Logistic Models; D035002:Lower Extremity / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010689:Phlebitis; D011655:Pulmonary Embolism / Q000150:complications*; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D020246:Venous Thrombosis / Q000209:etiology*; D055815:Young Adult