title: Review of laser speckle contrast techniques for visualizing tissue perfusion.
abstract: When a diffuse object is illuminated with coherent laser light, the backscattered light will form an interference pattern on the detector. This pattern of bright and dark areas is called a speckle pattern. When there is movement in the object, the speckle pattern will change over time. Laser speckle contrast techniques use this change in speckle pattern to visualize tissue perfusion. We present and review the contribution of laser speckle contrast techniques to the field of perfusion visualization and discuss the development of the techniques.
authors.affiliation: Biophysical Engineering Group Institute for Biomedical Technology, University of Twente, Enschede, The Netherlands. m.j.draijer@utwente.nl
authors.forename: Matthijs
authors.initials: M
authors.lastname: Draijer
authors.forename: Erwin
authors.initials: E
authors.lastname: Hondebrink
authors.forename: Ton
authors.initials: T
authors.lastname: van Leeuwen
authors.forename: Wiendelt
authors.initials: W
authors.lastname: Steenbergen
mesh_terms: D000818:Animals; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007834:Lasers; D010363:Pattern Recognition, Automated / Q000379:methods / Q000706:statistics & numerical data; D010781:Photography; D012039:Regional Blood Flow; D012542:Scattering, Radiation; D012867:Skin / Q000098:blood supply