Positive rK39 serologic assay results in US servicemen with cutaneous leishmaniasis.
The rK39 test is a serologic assay for the rapid diagnosis of visceral leishmaniasis (VL). Serum from a North American cohort of 59 otherwise asymptomatic soldiers with cutaneous leishmaniasis (CL) was tested with the rK39 dipstick and ELISA assays, and 10.2% and 28.8% had positive results, respectively. CL is associated with a reactive rK39 assay result in some patients without clinical evidence of VL.
Hartzell
Joshua D
JD
Infectious Diseases Division, Walter Reed Army Medical Center, Washington, District of Columbia 20307, USA. joshua.hartzell@amedd.army.mil
Aronson
Naomi E
NE
Weina
Peter J
PJ
Howard
Robin S
RS
Yadava
Anjali
A
Wortmann
Glenn W
GW
D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000097:blood* / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D008889:Military Personnel; D015800:Protozoan Proteins / Q000276:immunology*; D011994:Recombinant Proteins / Q000276:immunology; D012698:Serologic Tests; D014481:United States
D000913:Antibodies, Protozoan; D015800:Protozoan Proteins; D011994:Recombinant Proteins