title: Wavelet based noise reduction in CT-images using correlation analysis.
abstract: The projection data measured in computed tomography (CT) and, consequently, the slices reconstructed from these data are noisy. We present a new wavelet based structure-preserving method for noise reduction in CT-images that can be used in combination with different reconstruction methods. The approach is based on the assumption that data can be decomposed into information and temporally uncorrelated noise. In CT two spatially identical images can be generated by reconstructions from disjoint subsets of projections: using the latest generation dual source CT-scanners one image can be reconstructed from the projections acquired at the first, the other image from the projections acquired at the second detector. For standard CT-scanners the two images can be generated by splitting up the set of projections into even and odd numbered projections. The resulting images show the same information but differ with respect to image noise. The analysis of correlations between the wavelet representations of the input images allows separating information from noise down to a certain signal-to-noise level. Wavelet coefficients with small correlation are suppressed, while those with high correlations are assumed to represent structures and are preserved. The final noise-suppressed image is reconstructed from the averaged and weighted wavelet coefficients of the input images. The proposed method is robust, of low complexity and adapts itself to the noise in the images. The quantitative and qualitative evaluation based on phantom as well as real clinical data showed, that high noise reduction rates of around 40% can be achieved without noticeable loss of image resolution.
authors.affiliation: Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Chair of Pattern Recognition, 91058 Erlangen, Germany. anja.borsdorf@infomatik.uni-erlangen.de
authors.forename: Anja
authors.initials: A
authors.lastname: Borsdorf
authors.forename: Rainer
authors.initials: R
authors.lastname: Raupach
authors.forename: Thomas
authors.initials: T
authors.lastname: Flohr
authors.forename: Joachim
authors.initials: J
authors.lastname: Hornegger
mesh_terms: D000465:Algorithms; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D015233:Models, Statistical; D019047:Phantoms, Imaging; D016012:Poisson Distribution; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D013223:Statistics as Topic; D015898:Tomography Scanners, X-Ray Computed; D014057:Tomography, X-Ray Computed / Q000379:methods*