title: Randomized study of percutaneous endoscopic gastrostomy versus nasogastric tubes for enteral feeding in head and neck cancer patients treated with (chemo)radiation.
abstract: Percutaneous endoscopic gastrostomy (PEG) tubes have largely replaced nasogastric tubes (NGT) for nutritional support of patients with head and neck cancer undergoing curative (chemo)radiotherapy without any good scientific basis. A randomized trial was conducted to compare PEG tubes and NGT in terms of nutritional outcomes, complications, patient satisfaction and cost. The study was closed early because of poor accrual, predominantly due to patients' reluctance to be randomized. There were 33 patients eligible for analysis. Nutritional support with both tubes was good. There were no significant differences in overall complication rates, chest infection rates or in patients' assessment of their overall quality of life. The cost of a PEG tube was 10 times that of an NGT. The duration of use of PEG tubes was significantly longer, a median 139 days compared with a median 66 days for NGT. We found no evidence to support the routine use of PEG tubes over NGT in this patient group.
authors.affiliation: Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. june.corry@petermac.org
authors.forename: J
authors.initials: J
authors.lastname: Corry
authors.forename: W
authors.initials: W
authors.lastname: Poon
authors.forename: N
authors.initials: N
authors.lastname: McPhee
authors.forename: A D
authors.initials: AD
authors.lastname: Milner
authors.forename: D
authors.initials: D
authors.lastname: Cruickshank
authors.forename: S V
authors.initials: SV
authors.lastname: Porceddu
authors.forename: D
authors.initials: D
authors.lastname: Rischin
authors.forename: L J
authors.initials: LJ
authors.lastname: Peters
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D016145:Endoscopy, Digestive System / Q000706:statistics & numerical data*; D004750:Enteral Nutrition / Q000295:instrumentation* / Q000706:statistics & numerical data*; D005260:Female; D005774:Gastrostomy / Q000706:statistics & numerical data*; D006258:Head and Neck Neoplasms / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life