Study of the correlation between clinical efficiency of impaza and serum ADMA level.
Correlation between superlow-dose antibodies to endothelial NO synthase (Impaza) and serum level of ADMA was evaluated in a double blind placebo-controlled study. The reduction of ADMA in patients with erectile dysfunction after impaza treatment was paralleled by improvement of clinical symptoms. No clear-cut correlation between ADMA level and impaza effect was detected.
Zhavbert
E S
ES
nauka@materiamedica.ru
Tarasov
S A
SA
Dugina
J L
JL
Sergeeva
S A
SA
Gamidov
S I
SI
Mazo
E B
EB
Epstein
O I
OI
D000328:Adult; D000906:Antibodies / Q000627:therapeutic use*; D001120:Arginine / Q000031:analogs & derivatives* / Q000097:blood; D004311:Double-Blind Method; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D052250:Nitric Oxide Synthase Type III / Q000276:immunology*
D000906:Antibodies; C018524:N,N-dimethylarginine; D001120:Arginine; D052250:Nitric Oxide Synthase Type III