Gingival overgrowth in a renal transplant recipient using cyclosporine A.
Unsightly gingival enlargement is a frequent side effect in organ transplant recipients under immunosuppressive therapy with cyclosporin A (CsA). The purpose of this article was to report the treatment management of cyclosporin A-induced gingival overgrowth in a 9-year-old renal transplant recipient. Surgical reduction of the overgrown gingival tissue associated with an intensive biofilm control program and conversion from CsA to tacrolimus provided good clinical outcome with improvement of mastication, feeding, and phonetics. Gingival overgrowth stabilized with the change of medication. After approximately 3 months of follow-up, a regression of gingival enlargement was observed.
Gonçalves
Soraya Cheier Dib
SC
Department of Pediatric Clinics, Preventive and Social Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil.
Díaz-Serrano
Kranya Victoria
KV
de Queiroz
Alexandra Mussolino
AM
Palioto
Daniela Bazan
DB
Faria
Gisele
G
D002648:Child; D016572:Cyclosporine / Q000009:adverse effects*; D003744:Dental Enamel Hypoplasia / Q000150:complications; D019214:Gingival Overgrowth / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D005890:Gingivectomy; D006801:Humans; D006983:Hypertrichosis / Q000150:complications; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016030:Kidney Transplantation; D008297:Male; D016559:Tacrolimus / Q000627:therapeutic use
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D016559:Tacrolimus