title: Chronic recurrent multifocal osteomyelitis in a patient with selective immunoglobulin M deficiency.
abstract: Chronic recurrent multifocal osteomyelitis is an unusual inflammatory process of unknown origin involving multiple osseous sites, often recurrently. Selective immunoglobulin M (IgM) deficiency is a rare primary immunodeficiency disease, which can be associated with autoimmune diseases such as systemic lupus erythematosus, Hashimoto's disease, or hemolytic anemia. Here we report a case of a chronic recurrent multifocal osteomyelitis coexisting with selective IgM deficiency.
authors.affiliation: Department of Pediatrics, Dokuz Eylul University Hospital, 35340, Balcova-Izmir, Turkey. balahan.bora@deu.edu.tr
authors.forename: Balahan
authors.initials: B
authors.lastname: Makay
authors.forename: Erbil
authors.initials: E
authors.lastname: Unsal
authors.forename: Ozden
authors.initials: O
authors.lastname: Anal
authors.forename: Dilek
authors.initials: D
authors.lastname: Güneş
authors.forename: Süleyman
authors.initials: S
authors.lastname: Men
authors.forename: Handan
authors.initials: H
authors.lastname: Cakmakçi
authors.forename: Erdener
authors.initials: E
authors.lastname: Ozer
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D018771:Arthralgia / Q000276:immunology / Q000503:physiopathology; D001327:Autoimmune Diseases / Q000097:blood / Q000276:immunology* / Q000503:physiopathology; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D002634:Chemotaxis, Leukocyte / Q000276:immunology; D002648:Child; D002908:Chronic Disease / Q000188:drug therapy; D005269:Femur / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood / Q000172:deficiency*; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010019:Osteomyelitis / Q000097:blood / Q000276:immunology* / Q000503:physiopathology; D010388:Pelvis / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology; D011877:Radionuclide Imaging; D012008:Recurrence; D013131:Spine / Q000473:pathology; D012460:Sulfasalazine / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D015415:Biomarkers; D007075:Immunoglobulin M; D012460:Sulfasalazine