Updated recommendations for managing the care of patients receiving oral bisphosphonate therapy: an advisory statement from the American Dental Association Council on Scientific Affairs.
BACKGROUND
and Overview. In 2005, the American Dental Association (ADA) Council on Scientific Affairs convened an expert panel to develop clinical recommendations for dentists treating patients who are receiving oral bisphosphonate therapy. The Journal of the American Dental Association published the resulting report in 2006. This 2008 advisory statement is the first of projected periodic updates of the 2006 clinical recommendations.


CONCLUSIONS
This 2008 advisory statement concludes, on the basis of a review of the current literature, that for patients receiving bisphosphonate therapy, the risk of developing bisphosphonate-associated osteonecrosis (BON) of the jaw apparently remains low. It also newly concludes that current screening and diagnostic tests are unreliable for predicting a patient's risk of developing the condition. This statement updates the 2006 recommendations regarding general dentistry, management of periodontal diseases, implant placement and maintenance, oral and maxillofacial surgery, endodontics, restorative dentistry and prosthodontics, and orthodontics.
Edwards
Beatrice J
BJ
Department of Medicine and Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, USA.
Hellstein
John W
JW
Jacobsen
Peter L
PL
Kaltman
Steven
S
Mariotti
Angelo
A
Migliorati
Cesar A
CA
D000571:American Dental Association; D050071:Bone Density Conservation Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003729:Dental Care; D017742:Dental Care for Chronically Ill; D004164:Diphosphonates / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000517:prevention & control* / Q000628:therapy; D010020:Osteonecrosis / Q000139:chemically induced / Q000175:diagnosis / Q000517:prevention & control* / Q000628:therapy; D010024:Osteoporosis / Q000188:drug therapy; D017410:Practice Guidelines as Topic; D014481:United States
D050071:Bone Density Conservation Agents; D004164:Diphosphonates