title: Poly(n-butyl cyanoacrylate) nanoparticles via miniemulsion polymerization. 2. PEG-based surfactants.
abstract: This study aimed at synthesizing PEG-coated poly(n-butyl cyanoacrylate) nanoparticles by miniemulsion polymerization. Despite the high reactivity of butyl cyanoacrylate, nanoparticles were successfully obtained by miniemulsion polymerization of butyl cyanoacrylate-in-water emulsions stabilized by three PEG-based surfactants: Brij78, Brij700, and Tween80. Their physico-chemical properties were thoroughly investigated as a function of surfactant structure and concentration and discussed on the basis of results obtained from interfacial tension measurements (dodecane-water). Results clearly showed the influence of the length of the PEG part of the surfactant on the final properties of the particles.
authors.affiliation: Laboratoire de Chimie Physique Macromoléculaire, Nancy-Université, CNRS, 1 rue Grandville, B.P. 20451, F-54001 Nancy, France.
authors.forename: M
authors.initials: M
authors.lastname: Wu
authors.forename: E
authors.initials: E
authors.lastname: Dellacherie
authors.forename: A
authors.initials: A
authors.lastname: Durand
authors.forename: E
authors.initials: E
authors.lastname: Marie
mesh_terms: D000327:Adsorption; D003911:Dextrans / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry*; D004659:Enbucrilate / Q000737:chemistry*; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry*; D013499:Surface Properties; D013500:Surface Tension; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D003911:Dextrans; D004655:Emulsions; D013501:Surface-Active Agents; D011092:Polyethylene Glycols; D004659:Enbucrilate