title: Development of a synthetic bone scaffold using porous hydroxyapatite for bone repair.
abstract: In this study, porous hydroxyapatite (HA) samples were fabricated via sponge techniques with the aid of sago as part of the binder mixture. Development processes for the production of porous bone graft substitutes are studied using polyurethane sponge. To obtain the optimum amount of binder for successful fabrication of porous HA were done. Initially, porous HA powder was synthesized using calcium hydroxide and orthorphosphoric acid. Meanwhile, sago was mixed with PVA in a certain ratio to be used as binder for preparing the porous HA. After a series of investigative tests were conducted to characterize the sintered samples, the use of the sago and polymeric mixture was found to successfully aid the fabrication of porous HA samples. In this investigation, comparison of physical and mechanical characteristics between samples prepared using difference techniques was made.
authors.affiliation: Material Technology Group (MTEG), Industrial Technology Division, Malaysian Nuclear Agency, Bangi, 43000 Kajang, Selangor DE. rusnah_m@nuclearmalaysia.gov.my
authors.forename: R
authors.initials: R
authors.lastname: Mustaffa
authors.forename: I
authors.initials: I
authors.lastname: Besar
authors.forename: M
authors.initials: M
authors.lastname: Andanastuti
mesh_terms: D001696:Biomechanical Phenomena; D015519:Bone Density; D018786:Bone Substitutes / Q000138:chemical synthesis / Q000737:chemistry*; D016025:Bone Transplantation; D001842:Bone and Bones / Q000737:chemistry* / Q000293:injuries; D002126:Calcium Hydroxide / Q000737:chemistry; D017886:Durapatite / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D010756:Phosphoric Acids / Q000737:chemistry; D010865:Pilot Projects; D011108:Polymers; D016062:Porosity; D023822:Tissue Engineering; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D018786:Bone Substitutes; D010756:Phosphoric Acids; D011108:Polymers; D017886:Durapatite; C030242:phosphoric acid; D002126:Calcium Hydroxide