title: Impact of anesthetic agents on cerebrovascular physiology in children.
abstract: The role of the pediatric neuroanesthetist is to provide comprehensive care to children with neurologic pathologies. The cerebral physiology is influenced by the developmental stage of the child. The understanding of the effects of anesthetic agents on the physiology of cerebral vasculature in the pediatric population has significantly increased in the past decade allowing a more rationale decision making in anesthesia management. Although no single anesthetic technique can be recommended, sound knowledge of the principles of cerebral physiology and anesthetic neuropharmacology will facilitate the care of pediatric neurosurgical patients.
authors.affiliation: Department of Anaesthesia, University of Toronto, Toronto, ON, Canada. elod.szabo@sickkids.ca
authors.forename: Elöd Z
authors.initials: EZ
authors.lastname: Szabó
authors.forename: Igor
authors.initials: I
authors.lastname: Luginbuehl
authors.forename: Bruno
authors.initials: B
authors.lastname: Bissonnette
mesh_terms: D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D001921:Brain / Q000098:blood supply*; D002555:Cerebrospinal Fluid / Q000187:drug effects / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology; D002648:Child; D006706:Homeostasis / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects / Q000502:physiology; D016343:Monitoring, Intraoperative / Q000379:methods; D019635:Neurosurgical Procedures; D019990:Perioperative Care
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous