title: Vertebroplasty for the treatment of traumatic nonosteoporotic compression fractures.
abstract: OBJECTIVE
  Vertebroplasty is commonly used for osteoporotic and neoplastic compression fractures, yet little evidence exists for its use in traumatic nonosteoporotic compression fractures. The purpose of this study was to evaluate the safety and efficacy of percutaneous vertebroplasty for patients with traumatic nonosteoporotic compression fractures.
  
  
  METHODS
  We performed a retrospective review of 819 patients (982 procedures) who underwent percutaneous vertebroplasty, to identify patients who had normal bone mineral densitometry scores or had no previous diagnosis of osteoporosis, multiple myeloma, or history of long-term steroid use. Follow-up evaluations included pain at rest and with activity (assessed with the visual analog scale [VAS]), medication use, and mobility. Roland-Morris Disability Questionnaire (RDQ) scores were also collected. Statistical analysis included a 2-tailed t test comparing postprocedure outcomes with baseline values.
  
  
  RESULTS
  Fifteen patients (53% women) were included. Mean age and t-score were 60 years and -0.35, respectively. We found significant improvements in the VAS scores, both at rest and with activity, and in the RDQ scores, starting at the 2-hour follow-up. Additionally, we found marked decreases in medication use and improvements in mobility. The complication rate was low and characterized by asymptomatic extravasation of cement.
  
  
  CONCLUSIONS
  From our study, we have shown that vertebroplasty can be successfully and safely used in patients with traumatic nonosteoporotic compression fractures. Vertebroplasty in these patients should be used after failure of conservative treatments and may be used in place of more invasive spinal reconstruction techniques.
authors.affiliation: Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Knavel
authors.forename: K R
authors.initials: KR
authors.lastname: Thielen
authors.forename: D F
authors.initials: DF
authors.lastname: Kallmes
mesh_terms: D000063:Accidents, Traffic; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D050815:Fractures, Compression / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D010149:Postoperative Pain; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery*; D013124:Spinal Injuries / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty