Novel borna virus in psittacine birds with proventricular dilatation disease.
Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus. Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds.
Honkavuori
Kirsi S
KS
Columbia University, New York, NY, USA.
Shivaprasad
H L
HL
Williams
Brent L
BL
Quan
Phenix Lan
PL
Hornig
Mady
M
Street
Craig
C
Palacios
Gustavo
G
Hutchison
Stephen K
SK
Franca
Monique
M
Egholm
Michael
M
Briese
Thomas
T
Lipkin
W Ian
WI
D000311:Adrenal Glands / Q000821:virology; D000818:Animals; D001715:Bird Diseases / Q000821:virology*; D001891:Borna disease virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D001921:Brain / Q000821:virology; D004108:Dilatation, Pathologic / Q000662:veterinary*; D011531:Proventriculus / Q000821:virology*; D011563:Psittaciformes / Q000821:virology*; D013045:Species Specificity; D013272:Stomach Diseases / Q000662:veterinary* / Q000821:virology; D013577:Syndrome