title: Gingival overgrowth in a renal transplant recipient using cyclosporine A.
abstract: Unsightly gingival enlargement is a frequent side effect in organ transplant recipients under immunosuppressive therapy with cyclosporin A (CsA). The purpose of this article was to report the treatment management of cyclosporin A-induced gingival overgrowth in a 9-year-old renal transplant recipient. Surgical reduction of the overgrown gingival tissue associated with an intensive biofilm control program and conversion from CsA to tacrolimus provided good clinical outcome with improvement of mastication, feeding, and phonetics. Gingival overgrowth stabilized with the change of medication. After approximately 3 months of follow-up, a regression of gingival enlargement was observed.
authors.affiliation: Department of Pediatric Clinics, Preventive and Social Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil.
authors.forename: Soraya Cheier Dib
authors.initials: SC
authors.lastname: Gonçalves
authors.forename: Kranya Victoria
authors.initials: KV
authors.lastname: Díaz-Serrano
authors.forename: Alexandra Mussolino
authors.initials: AM
authors.lastname: de Queiroz
authors.forename: Daniela Bazan
authors.initials: DB
authors.lastname: Palioto
authors.forename: Gisele
authors.initials: G
authors.lastname: Faria
mesh_terms: D002648:Child; D016572:Cyclosporine / Q000009:adverse effects*; D003744:Dental Enamel Hypoplasia / Q000150:complications; D019214:Gingival Overgrowth / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D005890:Gingivectomy; D006801:Humans; D006983:Hypertrichosis / Q000150:complications; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016030:Kidney Transplantation; D008297:Male; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D016559:Tacrolimus