title: Biosynthetic origin of the 1-oxygen of umbelliferone in the root tissue of sweet potato.
abstract: Oxidation of p-coumarate at the ortho-position is a key step to form umbelliferone. A tracer analysis using (18)O2 was performed in order to take information about the formation of umbelliferone in the root tissue of sweet potato. Mass fragmentation experiments revealed incorporation of an 18O atom into the 1-position of umbelliferone. This result indicates that the lactone of umbelliferone is formed via ortho-hydroxylation of the p-coumarate unit using O2.
authors.affiliation: Institute for Chemical Research, Gokasho Uji, Kyoto, 611-0011, Japan. bsimz@scl.kyoto-u.ac.jp
authors.forename: Bun-ichi
authors.initials: B
authors.lastname: Shimizu
authors.forename: Kosuke
authors.initials: K
authors.lastname: Kai
authors.forename: Michiko
authors.initials: M
authors.lastname: Tamai
authors.forename: Hikaru
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: Masaharu
authors.initials: M
authors.lastname: Mizutani
authors.forename: Kanzo
authors.initials: K
authors.lastname: Sakata
mesh_terms: D002934:Cinnamates / Q000378:metabolism*; D003374:Coumarins / Q000378:metabolism; D027723:Ipomoea batatas / Q000737:chemistry / Q000378:metabolism*; D007700:Kinetics; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D014468:Umbelliferones / Q000096:biosynthesis* / Q000737:chemistry
chemical_list: D002934:Cinnamates; D003374:Coumarins; D014468:Umbelliferones; C029010:cinnamic acid; C031477:7-hydroxycoumarin; C030123:coumarin