Heterophile antibody interference with thyroid assay.
Immunoassays are one of the main methods of measuring thyroid hormones. They are prone to interference. Interference of the immunoassays has been increasingly recognized as a problem because it may lead to misinterpretation of results resulting in unnecessary investigation and wrong course of treatment. We describe a patient who had interference in her thyroid function measurements (free T4, free T3 and TSH) during the course of treatment for Graves' disease.
Chin
Kek Peng
KP
Department of Endocrinology, Singapore General Hospital, Singapore. kek.peng.chin@sgh.com.sg
Pin
Yeo Chin
YC
D000910:Antibodies, Heterophile / Q000097:blood*; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007118:Immunoassay; D008163:Luminescent Measurements; D013960:Thyroid Function Tests; D013961:Thyroid Gland
D000910:Antibodies, Heterophile