title: Evaluation of mifepristone as a once a month contraceptive pill.
abstract: OBJECTIVE
  The purpose of this study was to assess the efficacy and safety of mifepristone as a contraceptive pill.
  
  
  METHODS
  A prospective case-control study was conducted in a tertiary care center of North India. The study group (n = 86) was given 200-mg mifepristone tablets on the 16th day of the menstrual cycle. The control group (n = 92) received combined oral contraceptive (COC) as per protocol. Subjects were followed for drug compliance, satisfaction, side effects, and failure.
  
  
  RESULTS
  Acceptability of mifepristone was significantly higher in educated population (P < .001), with fewer side effects (P = .001), good satisfaction (P < .001), and higher compliance rate (P = .05). The oral contraceptive pill group had higher adverse biochemical parameters.
  
  
  CONCLUSIONS
  Mifepristone can be used as a monthly contraceptive pill effectively.
authors.affiliation: Department of Obstetrics and Gynecology, CSM Medical University (Upgraded King George's Medical University), Lucknow, UP, India.
authors.forename: Mukta
authors.initials: M
authors.lastname: Agarwal
authors.forename: Vinita
authors.initials: V
authors.lastname: Das
authors.forename: Anjoo
authors.initials: A
authors.lastname: Agarwal
authors.forename: Amita
authors.initials: A
authors.lastname: Pandey
authors.forename: Deepali
authors.initials: D
authors.lastname: Srivastava
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003267:Contraception / Q000379:methods*; D003280:Contraceptives, Oral, Synthetic / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007194:India; D008597:Menstrual Cycle; D015735:Mifepristone / Q000008:administration & dosage* / Q000009:adverse effects; D017060:Patient Satisfaction; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D003280:Contraceptives, Oral, Synthetic; D015735:Mifepristone