title: Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia.
abstract: Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures were elucidated on the basis of extensive spectroscopic and single-crystal X-ray diffraction analyses. Compounds 1-14 exhibited weak anti-HIV-1 activities in vitro.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China.
authors.forename: Jian-Chao
authors.initials: JC
authors.lastname: Chen
authors.forename: Wu-Qing
authors.initials: WQ
authors.lastname: Liu
authors.forename: Lu
authors.initials: L
authors.lastname: Lu
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Qiu
authors.forename: Yong-Tang
authors.initials: YT
authors.lastname: Zheng
authors.forename: Liu-Meng
authors.initials: LM
authors.lastname: Yang
authors.forename: Xian-Min
authors.initials: XM
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.forename: Zhong-Rong
authors.initials: ZR
authors.lastname: Li
mesh_terms: D008958:Models, Molecular; D015394:Molecular Structure; D029777:Momordica charantia / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D014315:Triterpenes