title: Increased history of childhood and lifetime traumatic events among adults with alopecia areata.
abstract: BACKGROUND
  Whether adult alopecia areata (AA) is associated with childhood or total lifetime traumatic events is not known. Previous studies have investigated only the relationship with recent stressful events.
  
  
  OBJECTIVE
  We sought to determine whether patients with AA experience more childhood or total lifetime traumatic events, as measured by the Traumatic Experiences Checklist.
  
  
  METHODS
  Using a case-control study, data on 90 patients with AA and 91 control subjects were analyzed.
  
  
  RESULTS
  Significantly more patients with AA experienced total lifetime and early childhood traumatic events, with an odds ratio of 2.46 (95% confidence interval 1.15-5.28; P = .017) and 2.16 (1.15-4.06; P = .016), respectively. In patients with AA, the global impact score related to their traumatic experiences was significantly higher than in control subjects (P < .001). In addition, patients with AA experienced significantly more emotionally and physically traumatic events.
  
  
  CONCLUSIONS
  This case-control study is susceptible to recall bias and to confounding factors associated with stress caused by AA outbreaks or by a traumatic childhood history.
  
  
  CONCLUSIONS
  Our study documents an increased history of childhood trauma in patients with AA compared with control subjects.
authors.affiliation: Department of Dermatology, Universitair Ziekenhuis Brussels, Brussels, Belgium. riawil@scarlet.be
authors.forename: Ria
authors.initials: R
authors.lastname: Willemsen
authors.forename: Johan
authors.initials: J
authors.lastname: Vanderlinden
authors.forename: Diane
authors.initials: D
authors.lastname: Roseeuw
authors.forename: Patrick
authors.initials: P
authors.lastname: Haentjens
mesh_terms: D000328:Adult; D000506:Alopecia Areata / Q000453:epidemiology* / Q000523:psychology*; D016022:Case-Control Studies; D002648:Child; D002649:Child Abuse / Q000706:statistics & numerical data; D002650:Child Abuse, Sexual / Q000706:statistics & numerical data; D017579:Domestic Violence / Q000706:statistics & numerical data; D005192:Family Health; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D013315:Stress, Psychological / Q000453:epidemiology*; D011795:Surveys and Questionnaires