title: Monitoring of chemotherapy response in malignant pleural mesothelioma using fluorodeoxyglucose positron emission tomography.
abstract: We report a 56-year-old man who underwent monitoring of the response to chemotherapy of malignant pleural mesothelioma (MPM). (8)F-fluoro-2-deoxy-(D)-glucose positron emission tomography (FDG-PET) and computed tomography (CT) were performed prior to chemotherapy and after the first and second courses of chemotherapy. The tumor lesion exhibited shrinkage on CT and a decrease in the standardized uptake value (SUV) max after the first course of chemotherapy, but exhibited size enlargement and an increase in SUV max after the second course of chemotherapy. These findings suggest that results of quantification of metabolic response by FDG-PET are related to the objective response as determined by CT in patients with MPM.
authors.affiliation: Department of Respiratory Medicine, Osaka City University, Osaka. kimutats@med.osaka-cu.ac.jp
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kimura
authors.forename: Koichi
authors.initials: K
authors.lastname: Koyama
authors.forename: Shinzoh
authors.initials: S
authors.lastname: Kudoh
authors.forename: Joji
authors.initials: J
authors.lastname: Kawabe
authors.forename: Naruo
authors.initials: N
authors.lastname: Yoshimura
authors.forename: Shigeki
authors.initials: S
authors.lastname: Mitsuoka
authors.forename: Susumu
authors.initials: S
authors.lastname: Shiomi
authors.forename: Kazuto
authors.initials: K
authors.lastname: Hirata
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D016903:Drug Monitoring / Q000379:methods*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D049268:Positron-Emission Tomography / Q000379:methods*
chemical_list: D000970:Antineoplastic Agents; D019788:Fluorodeoxyglucose F18