Review of laser speckle contrast techniques for visualizing tissue perfusion.
When a diffuse object is illuminated with coherent laser light, the backscattered light will form an interference pattern on the detector. This pattern of bright and dark areas is called a speckle pattern. When there is movement in the object, the speckle pattern will change over time. Laser speckle contrast techniques use this change in speckle pattern to visualize tissue perfusion. We present and review the contribution of laser speckle contrast techniques to the field of perfusion visualization and discuss the development of the techniques.
Draijer
Matthijs
M
Biophysical Engineering Group Institute for Biomedical Technology, University of Twente, Enschede, The Netherlands. m.j.draijer@utwente.nl
Hondebrink
Erwin
E
van Leeuwen
Ton
T
Steenbergen
Wiendelt
W
D000818:Animals; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007834:Lasers; D010363:Pattern Recognition, Automated / Q000379:methods / Q000706:statistics & numerical data; D010781:Photography; D012039:Regional Blood Flow; D012542:Scattering, Radiation; D012867:Skin / Q000098:blood supply