title: Intraocular pressure in schizophrenic patients treated with psychiatric medications.
abstract: OBJECTIVE
  In order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications.
  
  
  METHODS
  Twenty-eight outpatients with DSM-IV diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with Goldmann applanation tonometry.
  
  
  RESULTS
  Raised intraocular pressure was found in three patients (11%). Abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. All these four patients were taking only ziprasidone.
  
  
  CONCLUSIONS
  Patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.
authors.affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brasil. valbns@yahoo.com.br
authors.forename: Valéria Barreto Novais E
authors.initials: VB
authors.lastname: Souza
authors.forename: Francisco José Rodrigues de
authors.initials: FJ
authors.lastname: Moura Filho
authors.forename: Fábio Gomes de Matos E
authors.initials: FG
authors.lastname: Souza
authors.forename: Sergio Augusto Carvalho
authors.initials: SA
authors.lastname: Pereira Filho
authors.forename: Suele Serra
authors.initials: SS
authors.lastname: Coelho
authors.forename: Fernando Antônio Mendes Lopes
authors.initials: FA
authors.lastname: Furtado
authors.forename: Tiago Bessa Almeida
authors.initials: TB
authors.lastname: Gonçalves
authors.forename: Karla Feitosa Ximenes
authors.initials: KF
authors.lastname: Vasconcelos
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*; D014065:Tonometry, Ocular; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents