title: [Obsessive-compulsive disorder].
abstract: Obsessive-compulsive disorder is a complex psychiatric disorder characterised by obsessions and/or compulsions. Obsessive-compulsive disorder has a relatively high prevalence and is a highly disabling disease. The disorder is associated with shame, which causes long delays in accessing treatment. Obsessive-compulsive disorder is caused by a complex interplay between genetic and environmental factors. Effective treatments exist in the form of either pharmacotherapy--clomipramine or selective serotonin reuptake inhibitors--or cognitive behaviour therapy.
authors.affiliation: Vrije Universiteit, afd. Biologische Psychologie, Van der Boechorststraat 1, 1081 BT Amsterdam. ds.van.grootheest@psy.vu.nl
authors.forename: D S
authors.initials: DS
authors.lastname: van Grootheest
authors.forename: O A
authors.initials: OA
authors.lastname: van den Heuvel
authors.forename: D C
authors.initials: DC
authors.lastname: Cath
authors.forename: P
authors.initials: P
authors.lastname: van Oppen
authors.forename: A J L M
authors.initials: AJ
authors.lastname: van Balkom
mesh_terms: D001521:Behavior Therapy / Q000379:methods*; D004777:Environment; D020022:Genetic Predisposition to Disease; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology* / Q000235:genetics / Q000517:prevention & control / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors