title: Neo-adjuvant chemoradiotherapy in advanced rectal carcinoma: a note of caution.
abstract: Rectal cancer remains a major source of morbidity and mortality with its prognosis relating directly to the initial stage of the disease at presentation. This report highlights the potentially serious morbidity and mortality, which may be associated with neo-adjuvant chemoradiotherapy in advanced rectal cancer, emphasising the need for thorough discussion with patients on the risks and benefits of such treatment.
authors.affiliation: Beaumont Hospital, Beaumont, Dublin 9. fanningdee@yahoo.co.uk
authors.forename: D M
authors.initials: DM
authors.lastname: Fanning
authors.forename: R S
authors.initials: RS
authors.lastname: Prichard
authors.forename: G
authors.initials: G
authors.lastname: Roche-Nagle
authors.forename: D
authors.initials: D
authors.lastname: McNamara
authors.forename: J
authors.initials: J
authors.lastname: Deasy
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000532:radiotherapy; D017809:Fatal Outcome; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy
chemical_list: D005472:Fluorouracil