title: [Dentistry oral hygiene and endocarditis. Pathophysiology and prophylactic therapy].
abstract: Infectious endocarditis is a cardiac pathology of bacterial, viral or more rarely mycotic origin developing on the surfaces of the endocardium or heart valves. Predisposing conditions are congenital malformations of the heart or valvular acquired alterations, as well as the presence of a valvular prosthesis. The microorganisms involved in the etiology and pathogenesis of the damage of such infection (bacterias, viruses or yeasts) determine the formation of the endocardic vegetations typical of this condition. Such lesions can be located on the valvular or the parietal endocardium and sometimes on the endothelium of a great artery. In despite of the elevated standards of instrumental investigations and therapeutic protocols, the bacterial endocarditis represents a pathology of wide interest, scientific and social, due to its high rate of incidence, morbility and mortality. Still now infectious endocarditis causes death in 20-30% of the patients. Although the significant progress on prevention of the infectious diseases and of the cross infections in dentistry practice, from the tartar ablation up to the oncologic oral surgery, still now the skills of oral hygiene and dentistry represent a potential threat for the development of an infectious endocarditis in predisposed patients. The authors, on the base of the revision of the literature and of their own clinical experience, show the etiology, pathophysiology and the clinical pictures related to such complex disease.
authors.affiliation: Dipartimento di Clinica Medica, Immunologia e Malattie Infettive, Unità di Tossicologia. l.santacroce@doc.uniba.it
authors.forename: Luigi
authors.initials: L
authors.lastname: Santacroce
authors.forename: Raffaele
authors.initials: R
authors.lastname: Cagiano
authors.forename: Roberto G
authors.initials: RG
authors.lastname: Carlaio
authors.forename: Raffaele
authors.initials: R
authors.lastname: Del Prete
authors.forename: Lucrezia
authors.initials: L
authors.lastname: Bottalico
mesh_terms: D003813:Dentistry; D004697:Endocarditis, Bacterial / Q000382:microbiology / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D009910:Oral Hygiene; D019647:Oral Surgical Procedures; D012307:Risk Factors