Microwave-assisted synthesis, characterization and biological activities of organotin (IV) complexes with some thio Schiff bases.
Microwave-assisted synthesis and characterization of the organotin (IV) complexes are reported. Trigonal bipyramidal and octahedral complexes of tin (IV) have been synthesized by the reaction of dimethyltin (IV) dichloride with 4-nitrobenzanilide-S-benzyldithiocarbazate (L(1)H), 4-chlorobenzanilide-S-benzyldithiocarbazate (L(2)H), 4-nitrobenzanilidebenzothiazoline (L(3)H) and 4-chlorobenzanilidebenzothiazoline (L(4)H). The complexes so formed were characterized by elemental analysis, conductance measurements, molecular weight determinations and spectral data viz. IR, UV-Visible, (1)H and (13)C NMR. The anti-microbial activities of the ligands and their corresponding organotin (IV) complexes have been screened against various strains of bacteria and fungi. Antifertility activity against male albino rats has also been reported.
Singh
Ran Vir
RV
Department of Chemistry, University of Rajasthan, Jaipur 302004, India. rvsjpr@hotmail.com
Chaudhary
Pratibha
P
Chauhan
Shikha
S
Swami
Monika
M
D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D005298:Fertility / Q000187:drug effects; D007536:Isomerism; D008024:Ligands; D008297:Male; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009947:Organotin Compounds / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry
D000890:Anti-Infective Agents; D008024:Ligands; D009947:Organotin Compounds; D012545:Schiff Bases; D013438:Sulfhydryl Compounds