[Preservation of women fertility facing potential premature ovarian failure].
Numerous pathologies and their treatments may alter ovarian reserve in women and girls and may harm their future fertility. Oocytes cryopreservation techniques may be used in a limited number of cases, excluding young patients. We hereby report results obtained with our and other teams' ovarian tissue vitrification techniques. This new approach can be offered to young patients before puberty and should not delay both chemotherapy and radiotherapy when needed. Major drawbacks include potential alteration of ovarian reserve, as well as recurrence of the original malignancy. The later can be circumvented using in vitro maturation techniques. It is important to discuss fertility preservation opportunities with every woman or girls facing potential premature ovarian failure.
Feki
Anis
A
Département de gynécologie et d'obstétrique, HUG, Genève. anis.feki@hcuge.ch
Fraisse
Timothée
T
Irion
Olivier
O
Dubuisson
Jean-Bernard
JB
Hovatta
Outi
O
D000328:Adult; D015925:Cryopreservation / Q000379:methods; D003451:Cryoprotective Agents / Q000627:therapeutic use; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009865:Oocytes; D009924:Organ Culture Techniques; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D010053:Ovary; D016649:Primary Ovarian Insufficiency / Q000628:therapy*; D027724:Reproductive Techniques, Assisted; D055815:Young Adult
D003451:Cryoprotective Agents