title: Immunologic pathogenesis of multiple sclerosis.
abstract: Multiple sclerosis (MS) is an autoimmune disease. The etiology and pathogenesis of MS remain unclear. At present, there are substantial evidences to support the hypothesis that genetics plays a crucial role. The people who have genetic predisposing genes easily develop immune-mediated disorder, probably in conjunction with environmental factors. The aim of this review is to describe recent observations regarding the immunologic pathogenesis of MS.
authors.affiliation: Institute of Brain Science, Shanxi Datong University, Datong, China.
authors.forename: Min-Fang
authors.initials: MF
authors.lastname: Guo
authors.forename: Ning
authors.initials: N
authors.lastname: Ji
authors.forename: Cun-Gen
authors.initials: CG
authors.lastname: Ma
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D006801:Humans; D008954:Models, Biological; D009103:Multiple Sclerosis / Q000209:etiology* / Q000276:immunology* / Q000473:pathology; D004676:Myelin Basic Protein / Q000378:metabolism
chemical_list: D001323:Autoantibodies; D004676:Myelin Basic Protein