Immunologic pathogenesis of multiple sclerosis.
Multiple sclerosis (MS) is an autoimmune disease. The etiology and pathogenesis of MS remain unclear. At present, there are substantial evidences to support the hypothesis that genetics plays a crucial role. The people who have genetic predisposing genes easily develop immune-mediated disorder, probably in conjunction with environmental factors. The aim of this review is to describe recent observations regarding the immunologic pathogenesis of MS.
Guo
Min-Fang
MF
Institute of Brain Science, Shanxi Datong University, Datong, China.
Ji
Ning
N
Ma
Cun-Gen
CG
D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D006801:Humans; D008954:Models, Biological; D009103:Multiple Sclerosis / Q000209:etiology* / Q000276:immunology* / Q000473:pathology; D004676:Myelin Basic Protein / Q000378:metabolism
D001323:Autoantibodies; D004676:Myelin Basic Protein