"What is it?" A functional MRI and SPECT study of ictal speech in a second language.
Neuronal networks involved in second language (L2) processing vary between normal subjects. Patients with epilepsy may have ictal speech automatisms in their second language. To delineate the brain systems involved in L2 ictal speech, we combined functional MRI during bilingual tasks and ictal--interictal single-photon emission computed tomography in a patient who presented L2 ictal speech productions. These analyses showed that the networks activated by the seizure and those activated by L2 processing intersected in the right hippocampus. These results may provide some insights both into the pathophysiology of ictal speech and into the brain organization for L2.
Navarro
Vincent
V
Department of Neurology, AP-HP, Hôpital de la Pitié-Salpêtrière, IFR 70, Paris, France. vincent.navarro@psl.aphp.fr
Delmaire
Christine
C
Chauviré
Valérie
V
Habert
Marie-Odile
MO
Footnick
Rosalie
R
Lehéricy
Stéphane
S
Baulac
Michel
M
Pallier
Christophe
C
Cohen
Laurent
L
D000328:Adult; D001332:Automatism / Q000209:etiology; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000503:physiopathology; D001931:Brain Mapping; D004569:Electroencephalography; D004827:Epilepsy / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D019303:Multilingualism; D010100:Oxygen / Q000097:blood; D013060:Speech; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
D010100:Oxygen