Cells of rhabdomyosarcoma PA-23 tumor clones with high and low metastatic potential differ by activity of lysosomal sialidase.
We studied activity of lysosomal sialidase in cells of rhabdomyosarcoma PA-23 tumor clones with high and low metastatic potential. Low activity of lysosomal sialidase was found in clones characterized by high metastatic potential.
Proshin
S N
SN
Department of Cellular and Molecular Pathology, A. M. Nikiforov Russian Center of Emergency and Radiation Medicine, Ministry of Emergency Situations.
Kaminskaya
E V
EV
Lebedev
A A
AA
Shabanov
P D
PD
D000818:Animals; D008247:Lysosomes / Q000201:enzymology; D009362:Neoplasm Metastasis / Q000473:pathology* / Q000503:physiopathology; D009439:Neuraminidase / Q000378:metabolism*; D051381:Rats; D012208:Rhabdomyosarcoma / Q000201:enzymology* / Q000473:pathology*
D009439:Neuraminidase