title: Diurnal cortisol secretion and 2-year changes in older adults' physical symptoms: the moderating roles of negative affect and sleep.
abstract: OBJECTIVE
  This study examined whether the association between cortisol secretion and changes in physical health symptoms would depend on other factors in a person's life. The authors expected that physical health effects would emerge particularly when cortisol disturbances co-occur in the context of high levels of trait negative affect or poor sleep.
  
  
  METHODS
  Physical symptoms, diurnal cortisol secretion, affective tendencies, and sleep efficiency were assessed in a 2-yr longitudinal study of 184 older adults.
  
  
  METHODS
  Two-year changes in physical symptoms.
  
  
  RESULTS
  High cortisol levels were associated with increases in physical symptoms, but only among participants who experienced high negative affect and poor sleep.
  
  
  CONCLUSIONS
  Elevated levels of cortisol secretion contribute to older adults' physical symptoms if they co-occur in the context of other emotional and behavioral problems. By contrast, cortisol disturbances may not influence physical symptoms among people who are emotionally well or engage in efficient sleep behaviors.
authors.affiliation: Department of Psychology, Centre for Research in Human Development, Concordia University, Montreal, QC H4B 1R6, Canada. carsten.wrosch@concordia.ca
authors.forename: Carsten
authors.initials: C
authors.lastname: Wrosch
authors.forename: Gregory E
authors.initials: GE
authors.lastname: Miller
authors.forename: Sonia
authors.initials: S
authors.lastname: Lupien
authors.forename: Jens C
authors.initials: JC
authors.lastname: Pruessner
mesh_terms: D000339:Affect; D000368:Aged; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012463:Saliva / Q000737:chemistry; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology* / Q000523:psychology*; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D006854:Hydrocortisone