title: Notoamides F-K, prenylated indole alkaloids isolated from a marine-derived Aspergillus sp.
abstract: Six new prenylated indole alkaloids, named notoamides F-K (8-13), were isolated from a marine-derived Aspergillus sp. Their structures, including absolute configurations, were elucidated by spectroscopic methods. Notoamide I (11) showed weak cytotoxicity against HeLa cells with an IC(50) value of 21 microg/mL.
authors.affiliation: Graduate School of Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. sachiko@faculty.chiba-u.jp
authors.forename: Sachiko
authors.initials: S
authors.lastname: Tsukamoto
authors.forename: Hikaru
authors.initials: H
authors.lastname: Kato
authors.forename: Masayuki
authors.initials: M
authors.lastname: Samizo
authors.forename: Yuka
authors.initials: Y
authors.lastname: Nojiri
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Onuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hirota
authors.forename: Tomihisa
authors.initials: T
authors.lastname: Ohta
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D049872:Bivalvia / Q000382:microbiology; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry; D008386:Marine Biology; D015394:Molecular Structure; D009792:Oceans and Seas
chemical_list: D000970:Antineoplastic Agents; D026121:Indole Alkaloids; C534639:notoamide I