[Characteristic of the yeast isolated from patients with leukaemia].
It has been shown that biotopes of upper respiratory system and intestine were contaminated with yeast in 44.6% of patients with leukaemia (of 112 examined ones). Their quantity exceeds the boundary value for practically healthy people and is > or = 10(2) KOE/ml in the nasal activity and fauces and < or = 10(4) KOE/g in the intestine. It was established that in patients with leucemia the mycotic complications are mainly caused by anamorphous yeast of ascomycetic affinity. Candida albicans, as well as C. glabrata, C. rugosa and Candida sp. play the leading role. The Candida genus species are mainly sensitive to amphotericine B, clotrisamol and nistatin.
Fedorovskaia
E A
EA
Rybal'skaia
A P
AP
Skachkova
N K
NK
Mel'nik
E A
EA
Nemirovskaia
L N
LN
Nagornaia
S S
SS
Babich
T V
TV
Polishchuk
L V
LV
D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000494:pharmacology; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D007938:Leukemia / Q000150:complications / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000382:microbiology / Q000517:prevention & control*; D009894:Opportunistic Infections / Q000150:complications / Q000382:microbiology / Q000517:prevention & control*; D012137:Respiratory System / Q000382:microbiology*; D015003:Yeasts / Q000187:drug effects / Q000302:isolation & purification*; D055815:Young Adult
D000935:Antifungal Agents