[Familial summer-type hypersensitivity pneumonitis in a husband and wife].
We encountered a family in which two of four members, the husband and his wife, had summer-type hypersensitivity pneumonitis at the same time, about two months after they moved to the residence. A 45-year-old man had cough, fever and exertional dyspnea. Chest computed tomography showed diffuse centriloblar ground-glass attenuation in both lung fields. His 43-year-old wife had chest small nodular shadows and similar symptoms to his husband. Serum anti-Tricosporon cutaneum (T. asahi: serotype II and T. mucoides: serotype I) antibodies of both patients were at the positive level. They were given diagnosis as summer-type hypersensitivity pneumonitis by radiological, serological and histological examinations. The symptoms in both cases were improved immediately after administration of systemic corticosteroid. Summer-type hypersensitivity pneumonitis was assumed to be caused for about two months duration of expousure to antigen.
Amemiya
Yuka
Y
Department of Internal Medicine II, Oita University Faculty of Medicine.
Shirai
Ryo
R
Ando
Syunji
S
Fujii
Hiroyuki
H
Iwata
Atsuko
A
Kai
Naoko
N
Otani
Satoshi
S
Umeki
Kenji
K
Ishii
Hiroshi
H
Kadota
Jun-Ichi
J
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D000908:Antibodies, Fungal / Q000097:blood; D000946:Antigens, Fungal / Q000009:adverse effects; D015415:Biomarkers / Q000097:blood; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018454:Spouses; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014250:Trichosporon / Q000276:immunology / Q000472:pathogenicity
D000305:Adrenal Cortex Hormones; D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D015415:Biomarkers