title: Low-grade endometrial stromal sarcoma of the uterus: review of 10 cases.
abstract: BACKGROUND
  Low-grade endometrial sarcoma is a rare gynecological tumor (0.2% of female genital tract tumors) mainly observed in women before their 50's.
  
  
  METHODS
  The authors present a series of 10 patients followed in two institutions and describe the treatment administered (cytoreductive surgery, i.e. bilateral annexectomy and total hysterectomy, and medical treatments) and the follow-up.
  
  
  CONCLUSIONS
  Local recurrence occurred in 70% of cases, whereas metastasis was rare even after suboptimal surgical removal of the tumor. Adjuvant progestin therapy is currently the most effective treatment for curing and preventing local recurrence. The use of aromatase inhibitors is a promising research approach.
authors.affiliation: Department of Obstetric Gynaecology, University Hospital, F-35203 Rennes Cedex 2, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Landréat
authors.forename: Nicolas
authors.initials: N
authors.lastname: Paillocher
authors.forename: Laurent
authors.initials: L
authors.lastname: Catala
authors.forename: Fabrice
authors.initials: F
authors.lastname: Foucher
authors.forename: Philippe
authors.initials: P
authors.lastname: Descamps
authors.forename: Jean
authors.initials: J
authors.lastname: Levêque
mesh_terms: D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D018203:Sarcoma, Endometrial Stromal / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*