title: Diagnosis and management of urinary tract infection in hospitalized older people.
abstract: OBJECTIVE
  To compare the diagnosis and management of urinary tract infection (UTI) in hospitalized older people with clinical criteria and therapeutic guidelines.
  
  
  METHODS
  A retrospective case series of emergency hospital admissions collected over an 18-month period.
  
  
  METHODS
  An acute general hospital in northwest England.
  
  
  METHODS
  Two hundred sixty-five patients aged 75 and older with a diagnosis of UTI at hospital discharge.
  
  
  METHODS
  Data relating to age, sex, presenting complaint, admission and discharge destinations, background comorbidities and medications, investigations performed, treatment given, length of stay, and complications were obtained using chart review.
  
  
  RESULTS
  Of the 265 patients (mean age 85.4) the overdiagnosis of UTI was common, with 43.4% of patients not meeting criteria. Only 32.1% of patients overall had any urinary tract symptoms (48.7% in the UTI group). Of the non-UTI group, 12 (10.4%) had urinary tract symptoms with a negative urine culture, 43 (37.4%) had asymptomatic bacteriuria (ASB), and 60 (52.2%) had neither urinary tract symptoms nor bacteriuria. Treatment given varied greatly. The mortality rate was 6.0%, and the average length of stay was 29.9 days (median 17.0, range 1-192). Complications were frequent, including Clostridium difficile diarrhea (8%), falls (4%), methicillin-resistant Staphylococcus aureus infection (3%), and fracture (2%).
  
  
  CONCLUSIONS
  More-reliable criteria are needed to aid the diagnosis of UTI in hospitalized older people. Better adherence to clinical management guidelines may improve outcomes.
authors.affiliation: Department of Elderly Medicine, Cumberland Infirmary, Carlisle, United Kingdom. henry.woodford@ncumbria-acute.nhs.uk
authors.forename: Henry J
authors.initials: HJ
authors.lastname: Woodford
authors.forename: James
authors.initials: J
authors.lastname: George
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D019983:Guideline Adherence; D006760:Hospitalization; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000628:therapy*