title: Characterization of drinking water treatment for virus risk assessment.
abstract: Removal or inactivation of viruses in drinking water treatment processes can be quantified by measuring the concentrations of viruses or virus indicators in water before and after treatment. Virus reduction is then calculated from the ratio of these concentrations. Most often only the average reduction is reported. That is not sufficient when treatment efficiency must be characterized in quantitative risk assessment. We present three simple models allowing statistical analysis of series of counts before and after treatment: distribution of the ratio of concentrations, and distribution of the probability of passage for unpaired and paired water samples. Performance of these models is demonstrated for several processes (long and short term storage, coagulation/filtration, coagulation/sedimentation, slow sand filtration, membrane filtration, and ozone disinfection) using microbial indicator data from full-scale treatment processes. All three models allow estimation of the variation in (log) reduction as well as its uncertainty; the results can be easily used in risk assessment. Although they have different characteristics and are present in vastly different concentrations, different viruses and/or bacteriophages appear to show similar reductions in a particular treatment process, allowing generalization of the reduction for each process type across virus groups. The processes characterized in this paper may be used as reference for waterborne virus risk assessment, to check against location specific data, and in case no such data are available, to use as defaults.
authors.affiliation: National Institute for Public Health and the Environment, RIVM, Bilthoven, The Netherlands. Peter.Teunis@rivm.nl <Peter.Teunis@rivm.nl>
authors.forename: P F M
authors.initials: PF
authors.lastname: Teunis
authors.forename: S A
authors.initials: SA
authors.lastname: Rutjes
authors.forename: T
authors.initials: T
authors.lastname: Westrell
authors.forename: A M
authors.initials: AM
authors.lastname: de Roda Husman
mesh_terms: D004202:Disinfectants / Q000494:pharmacology; D004203:Disinfection / Q000379:methods; D005374:Filtration / Q000295:instrumentation / Q000379:methods; D008567:Membranes, Artificial; D010126:Ozone; D018570:Risk Assessment; D014780:Viruses; D014871:Water Microbiology / Q000592:standards*; D018508:Water Purification / Q000379:methods*; D014881:Water Supply / Q000592:standards*
chemical_list: D004202:Disinfectants; D008567:Membranes, Artificial; D010126:Ozone