title: Azotemia in cats with feline hypertrophic cardiomyopathy: prevalence and relationships with echocardiographic variables.
abstract: OBJECTIVE
  The prevalence of renal azotemia in cats with acquired heart disease is not well documented. The aims of this study were therefore (1) to determine the prevalence of azotemia within a hospital population of cats with hypertrophic cardiomyopathy (HCM), and (2) to evaluate the relationship between echocardiographic variables and plasma urea and creatinine.
  
  
  METHODS
  134 client-owned cats were retrospectively studied including 102 cats with HCM and 32 control cats. A complete physical examination, electrocardiography, systolic arterial blood pressure measurement, thoracic radiographs, and echocardiography were performed. Plasma creatinine and urea were determined in all cats. The animal was considered azotemic if plasma creatinine was >1.8 mg/dL and/or urea >65 mg/dL (i.e. BUN> 30 mg/dL).
  
  
  RESULTS
  The prevalence of azotemia was lower in control cats (25.0%) than in cats with HCM (58.8%) (P=0.003). No significant differences in plasma urea and creatinine were observed between the HCM and control cats. There was no effect of plasma creatinine and urea on conventional echocardiographic variables in cats with HCM.
  
  
  CONCLUSIONS
  Azotemia is a frequent finding in cats with HCM but is not dependent on echocardiographic variables.
authors.affiliation: Unité de Cardiologie d'Alfort, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort Cedex, France.
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Gouni
authors.forename: Valérie
authors.initials: V
authors.lastname: Chetboul
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Pouchelon
authors.forename: Carolina
authors.initials: C
authors.lastname: Carlos Sampedrano
authors.forename: Christelle
authors.initials: C
authors.lastname: Maurey
authors.forename: Hervé P
authors.initials: HP
authors.lastname: Lefebvre
mesh_terms: D000818:Animals; D053099:Azotemia / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D001794:Blood Pressure; D002312:Cardiomyopathy, Hypertrophic / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D016022:Case-Control Studies; D002371:Cat Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D002415:Cats; D015897:Comorbidity; D003404:Creatinine / Q000097:blood*; D004452:Echocardiography / Q000662:veterinary*; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology / Q000662:veterinary; D008297:Male; D010808:Physical Examination / Q000662:veterinary; D015995:Prevalence; D013902:Radiography, Thoracic / Q000662:veterinary; D012189:Retrospective Studies; D014508:Urea / Q000097:blood*
chemical_list: D014508:Urea; D003404:Creatinine