title: A review of the off-label use of selamectin (Stronghold/Revolution) in dogs and cats.
abstract: Since its introduction approximately seven years ago, selamectin (Stronghold/Revolution, Pfizer Inc.) has been used off-label to treat a number of ecto- and endoparasite conditions in dogs and cats. It has been used as a successful prophylactic against Dirofilaria repens and as a treatment for Aelurostrongylus abstrusus in cats. It has also been used to treat notoedric mange, infestation with the nasal mite Pneumonyssoides caninum, Cheyletiella spp. and Neotrombicula autumnalis infestations and larval Cordylobia anthropophaga infection. However, to date attempts to treat generalised canine demodicosis have not been successful. In all cases, treatment was apparently well tolerated by the host.
authors.affiliation: Shernacre Enterprise, Shernacre Cottage, Lower Howsell Road, Malvern, Worcs WR14 1UX, UK. mfisher@globalnet.co.uk
authors.forename: Maggie A
authors.initials: MA
authors.lastname: Fisher
authors.forename: David J
authors.initials: DJ
authors.lastname: Shanks
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D002371:Cat Diseases / Q000188:drug therapy; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy; D004285:Dogs; D006374:Helminthiasis, Animal / Q000188:drug therapy*; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin; C414354:selamectin