[Neo-oogenesis, possibility of oryjgin of oocytes and primordial ovarian follicles in postnatal period in women].
The central dogma female reproductive biology has that oogenesis ceases around birth in mammals and human. The ovarian reserve of oocytes is definitely fixed and will deplete up to the menopause in women. The papers by Johnson et al. and Bukovsky et al. overturn this dogma since they claim that female mice and women produce new oocytes during adult life. In conclusion, these observations need to be confirmed by others, they could be considered to question the dogma of fixed stock of oocytes at birth.
Sliwa
Leopold
L
Zakład Biologii Rozwoju Człowieka, Instytut Pielegniarstwa i Połoznictwa Wydziału Nauk o Zdrowiu i Ochrony Zdrowia, Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków. leosliwa@cm-uj.krakow.pl
D000328:Adult; D000818:Animals; D005260:Female; D006801:Humans; D051379:Mice; D009866:Oogenesis / Q000502:physiology*; D006080:Ovarian Follicle / Q000166:cytology; D049590:Postpartum Period / Q000502:physiology*