title: Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia.
abstract: Using diffusion tensor imaging and tractography, we found that a disruption in structural connectivity in ventral occipito-temporal cortex may be the neurobiological basis for the lifelong impairment in face recognition that is experienced by individuals who suffer from congenital prosopagnosia. Our findings suggest that white-matter fibers in ventral occipito-temporal cortex support the integrated function of a distributed cortical network that subserves normal face processing.
authors.affiliation: Department of Psychology, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213, USA. cibut@nmr.mgh.harvard.edu
authors.forename: Cibu
authors.initials: C
authors.lastname: Thomas
authors.forename: Galia
authors.initials: G
authors.lastname: Avidan
authors.forename: Kate
authors.initials: K
authors.lastname: Humphreys
authors.forename: Kwan-jin
authors.initials: KJ
authors.lastname: Jung
authors.forename: Fuqiang
authors.initials: F
authors.lastname: Gao
authors.forename: Marlene
authors.initials: M
authors.lastname: Behrmann
mesh_terms: D000328:Adult; D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D008875:Middle Aged; D009778:Occipital Lobe / Q000473:pathology / Q000503:physiopathology; D020238:Prosopagnosia / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology*; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology; D014793:Visual Cortex / Q000473:pathology / Q000503:physiopathology*; D014795:Visual Pathways / Q000473:pathology / Q000503:physiopathology*