title: An armed-disarmed approach for blocking aglycon transfer of thioglycosides.
abstract: Thioglycosides are used frequently as glycosyl donors and as mimetics of O-glycosides. While being very useful, thioglycosides are prone to a detrimental side reaction referred to as aglycon transfer. In this paper, it is shown that aglycon transfer can be blocked by matching thioglycoside-containing acceptors with more armed glycosyl donors.
authors.affiliation: Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702 USA.
authors.forename: Zhitao
authors.initials: Z
authors.lastname: Li
authors.forename: Jeffrey C
authors.initials: JC
authors.lastname: Gildersleeve