[Seropositivity to Helicobacter pylori among university students and their families. A comparative cross-sectional study].
OBJECTIVE
To associate serologic response to Helicobacter pylori (Hp) among seropositive university students and their families in western Mexico.


METHODS
We conducted a comparative transversal study, and randomized 30 nuclear families of 14 Hp-seropositive university students and 14 Hp-seronegative university students. We carried out seropositivity measurements (IgG) to Hp using the ELISA method. An analysis was performed utilizing the chi-squared and Mann-Whitney U tests, with the aid of EPI INFO 2000 and SIGMA STAT 3.2 software.


RESULTS
Global seropositivity in the families of infected students was 57 vs. 13% of the relatives of non-infected students (p = 0.000002). In families of Hp-positive students we found the following frequencies: parental (father and mother) 70%; mother 71%, and siblings 42%, while for seronegative individuals incidences were: parental 17% (p = 0.00005), mother 12% (p = 0.001), and siblings 10% (p = 0.0076).


CONCLUSIONS
There is a greater prevalence of antibodies against Hp in the relatives of seropositive students.
Guzmán-Domínguez
G
G
Departamento de Salud y Bienestar, Centro Universitario del Sur, Universidad de Guadalajar, Ciudad Guzmán, Jalisco, México. gilberto.guzman@cusur.udg.mx
Newton-Sánchez
O A
OA
Bustos-Saldaña
R
R
Guzmán-Villa
B M
BM
Barajas-Martínez
A
A
D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005192:Family Health; D005260:Female; D016481:Helicobacter Infections / Q000097:blood*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D012698:Serologic Tests; D013334:Students; D014495:Universities; D055815:Young Adult
D007074:Immunoglobulin G