Cost-effectiveness analysis of behavioral interventions to improve vaccination compliance in homeless adults.
OBJECTIVE
To estimate the cost-effectiveness of three behavioral interventions provided to enhance hepatitis A virus (HAV) and hepatitis B virus (HBV) joint vaccination (HAV/HBV) compliance among homeless persons living in Los Angeles County.


METHODS
A cost-effectiveness analysis (CEA) based on data from a randomized trial where the costs and compliance data from the trial are incorporated into two Markov models, simulating the natural history of acute and chronic hepatitis infection, following HAV/HBV vaccination.


CONCLUSIONS
Reductions in HBV-related disease is cost-effective to society and is associated with substantial improvements in quality of life.
Greengold
Barbara
B
University of California, Los Angeles, School of Nursing, Box 956917, Los Angeles, CA 90095-6917, USA.
Nyamathi
Adeline
A
Kominski
Gerald
G
Wiley
Dorothy
D
Lewis
Mary Ann
MA
Hodge
Felicia
F
Singer
Mendel
M
Spiegel
Brennan
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D032763:Behavior Control / Q000379:methods*; D002986:Clinical Trials as Topic; D003362:Cost-Benefit Analysis; D006506:Hepatitis A / Q000517:prevention & control*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage*; D006509:Hepatitis B / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage*; D006703:Ill-Housed Persons; D006801:Humans; D015141:Los Angeles; D008875:Middle Aged; D010349:Patient Compliance; D055815:Young Adult
D022362:Hepatitis A Vaccines; D017325:Hepatitis B Vaccines