Sweet syndrome presenting as resistant conjunctivitis.
OBJECTIVE
We report a patient with chronic Sweet syndrome (SS) treated by anti-Tumor Necrosis Factor (TNF) therapy, who presented with a severe bilateral chemosis.


METHODS
Case report.


RESULTS
Conjunctival biopsy revealed an ocular localization of SS.


CONCLUSIONS
SS is a rare disorder that usually affects middle-age women. It is characterized by an acute febrile neutrophilic dermatosis. To our knowledge, this is the first documented case of an ocular localization in SS and the first report of a severe bilateral chemosis as ocular manifestation.
Michel
Guillaume
G
Department of Ophthalmology, Strasbourg University Hospital, Louis Pasteur University, Strasbourg, France. g67michel@yahoo.fr
Lhermitte
Benoist
B
Cribier
Bernard
B
Speeg-Schatz
Claude
C
Bourcier
Tristan
T
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use; D003228:Conjunctiva / Q000098:blood supply / Q000473:pathology; D003229:Conjunctival Diseases / Q000209:etiology* / Q000473:pathology; D003231:Conjunctivitis / Q000209:etiology*; D004305:Dose-Response Relationship, Drug; D004487:Edema / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006940:Hyperemia / Q000209:etiology; D000069285:Infliximab; D008297:Male; D012008:Recurrence; D016463:Sweet Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000911:Antibodies, Monoclonal; D000069285:Infliximab