Meningioma in untreated congenital adrenal hyperplasia: a relationship?
Steroid hormones have been implicated in the growth and/or development of meningiomas. A 46, XX male with untreated congenital adrenal hyperplasia who developed meningiomas is presented here. The meningiomas only expressed progesterone receptors, as most meningiomas do. The high 17-hydroxyprogesterone levels, resulting from his disease, could have played a role in the development and growth of his meningiomas.
Heijboer
Annemieke C
AC
Department of Clinical Chemistry, VU University Medical Center, Amsterdam, HV, 1081, The Netherlands. a.heijboer@vumc.nl
Netelenbos
J Coen
JC
Blankenstein
Marinus A
MA
D000312:Adrenal Hyperplasia, Congenital / Q000150:complications* / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000209:etiology* / Q000628:therapy; D008579:Meningioma / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged