title: One-pot synthesis of substituted furans using Cu(OTf)(2)-catalyzed propargylation/cycloisomerization tandem reaction.
abstract: A convenient one-pot propargylation/cycloisomerization tandem process has been developed for the synthesis of substituted furans derivatives from 1,3-dicarbonyl compounds and enoxysilanes with propargylic alcohols or acetates using copper(II) triflate as a bifunctional catalyst. This method provides a flexible and rapid route to substituted furans.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, P. R. China.
authors.forename: Ying-ming
authors.initials: YM
authors.lastname: Pan
authors.forename: Su-yan
authors.initials: SY
authors.lastname: Zhao
authors.forename: Wen-hua
authors.initials: WH
authors.lastname: Ji
authors.forename: Zhuang-ping
authors.initials: ZP
authors.lastname: Zhan
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D003300:Copper; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis*; D007536:Isomerism; D008722:Methods
chemical_list: D000480:Alkynes; D005663:Furans; D003300:Copper