title: Autonomic system disturbances in patients with increased intracranial pressure caused by brain tumors evaluated by heart rate variability.
abstract: Most of the disturbances of autonomic system (AS) activity seen in clinical practice result from head injury are due to development of increased intracranial pressure (ICP). It has been described that cerebral lesions produce hypersympathetic states mediated mostly by sympatho-adrenal discharge. Aim of the study was to evaluate effects of ICP on heart rate variability (HRV) in patients with brain tumors. We studied 24 patients, which were divided on two groups: with increased ICP before neurosurgery treatment caused by brain tumors with symptoms and without symptoms with treated ICP. Our results provided evidence that all patients with increased ICP had the autonomic system disturbances. The heart rate variability and cardiovascular reflexes are useful in identification of autonomic system dysfunction.
authors.affiliation: Department of Pathophysiology, Jagiellonian University, Medical College, Cracow, Poland.
authors.forename: Agata
authors.initials: A
authors.lastname: Furgała
authors.forename: Dorota
authors.initials: D
authors.lastname: Madroszkiewicz
authors.forename: Ewa
authors.initials: E
authors.lastname: Madroszkiewicz
authors.forename: Igor
authors.initials: I
authors.lastname: Gościński
authors.forename: Władysława
authors.initials: W
authors.lastname: Kolasińska-Kloch
authors.forename: Marek
authors.initials: M
authors.lastname: Moskała
authors.forename: Piotr J
authors.initials: PJ
authors.lastname: Thor
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D001342:Autonomic Nervous System Diseases / Q000209:etiology*; D001932:Brain Neoplasms / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006339:Heart Rate; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology*; D008297:Male; D008875:Middle Aged