Organelle transport: dynamic actin tracks for myosin motors.
Transport of cargo by molecular motors on microtubule and actin filament tracks is a fundamental property of eukaryotic cells. A new study reports that actin dynamics are required in cells for myosin I and V motor proteins to transport their organelle cargos on actin tracks.
Cramer
Louise
L
MRC-Laboratory Molecular Cell Biology/Cell Biology Unit and Department of Cell and Developmental Biology, University College London, Gower St, London WC1E 6BT, UK. l.cramer@ucl.ac.uk
D008841:Actin Cytoskeleton / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D001001:Anura / Q000378:metabolism; D001692:Biological Transport / Q000502:physiology; D008547:Melanophores / Q000378:metabolism / Q000648:ultrastructure; D024461:Myosin Type I / Q000378:metabolism / Q000502:physiology*; D024701:Myosin Type V / Q000378:metabolism / Q000502:physiology*; D015388:Organelles / Q000378:metabolism*
D024461:Myosin Type I; D024701:Myosin Type V