Vesicular Transport: EnSNAREd by GAPs.
How are SNARE proteins included into transport vesicles? One way is through the interaction with ArfGAP proteins. A recent study reports that the ArfGAP Hrb can wrap around the SNARE VAMP7, causing its endocytosis by clathrin-coated vesicles.
Poon
Pak P
PP
Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 1X5.
Spang
Anne
A
D001692:Biological Transport / Q000502:physiology; D022181:COP-Coated Vesicles / Q000378:metabolism*; D020690:GTPase-Activating Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D017434:Protein Structure, Tertiary; D050683:R-SNARE Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology
D020690:GTPase-Activating Proteins; D050683:R-SNARE Proteins