title: Herpes zoster and meningitis resulting from reactivation of varicella vaccine virus in an immunocompetent child.
abstract: Herpes zoster complicated by meningitis has been mainly reported in immunocompromised patients after reactivation of wild-type varicella-zoster virus. We present one of the first cases of aseptic meningitis after herpes zoster caused by reactivation of vaccine-type varicella-zoster virus in an immunocompetent child. We also highlight the increasing role of both wild-type and vaccine strains of varicella-zoster virus as a cause of viral meningoencephalitis and the use of appropriate laboratory tools to rapidly and accurately identify the virus in order to provide prompt patient care and management.
authors.affiliation: The Children's Hospital of Philadelphia, PA 19104-4399, USA. iyers@email.chop.edu
authors.forename: Sujit
authors.initials: S
authors.lastname: Iyer
authors.forename: Manoj K
authors.initials: MK
authors.lastname: Mittal
authors.forename: Richard L
authors.initials: RL
authors.lastname: Hodinka
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D002648:Child; D006562:Herpes Zoster / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008587:Meningitis, Viral / Q000188:drug therapy / Q000276:immunology*
chemical_list: D000998:Antiviral Agents; D019433:Chickenpox Vaccine; D000212:Acyclovir