Influence of bioengineered skin substitutes on diabetic foot ulcer and venous leg ulcer outcomes.
This systematic review indicates that bioengineered skin substitutes with a dermal component may improve healing outcomes in diabetic foot ulcers and venous leg ulcers. However, better designed trials with longer follow-up periods are needed.
Barber
C
C
ASERNIP-S, Royal Australasian College of Surgeons, Stepney, Australia.
Watt
A
A
Pham
C
C
Humphreys
K
K
Penington
A
A
Mutimer
K
K
Edwards
M
M
Maddern
G
G
D018929:Cell Culture Techniques; D002908:Chronic Disease; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use; D003094:Collagen / Q000627:therapeutic use; D017719:Diabetic Foot / Q000628:therapy*; D006301:Health Services Needs and Demand; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012449:Safety; D016038:Skin Transplantation; D017768:Skin, Artificial / Q000592:standards / Q000600:supply & distribution; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000628:therapy*; D014945:Wound Healing
C117898:Apligraf; C042816:Biobrane; D020099:Coated Materials, Biocompatible; C512800:TransCyte; D003094:Collagen