title: Survival of massive allografts in segmental oncological bone defect reconstructions.
abstract: Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.
authors.affiliation: Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors.forename: P H J
authors.initials: PH
authors.lastname: Bullens
authors.forename: N M
authors.initials: NM
authors.lastname: Minderhoud
authors.forename: M C
authors.initials: MC
authors.lastname: de Waal Malefijt
authors.forename: R P H
authors.initials: RP
authors.lastname: Veth
authors.forename: P
authors.initials: P
authors.lastname: Buma
authors.forename: H W B
authors.initials: HW
authors.lastname: Schreuder
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016025:Bone Transplantation; D002648:Child; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D005594:Fracture Fixation, Intramedullary / Q000295:instrumentation / Q000379:methods; D050723:Fractures, Bone / Q000209:etiology / Q000601:surgery; D006085:Graft Survival; D006801:Humans; D016268:Internal Fixators; D023821:Limb Salvage / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods / Q000401:mortality; D015996:Survival Rate; D055815:Young Adult