Return to the past: myocardial regeneration therapy.
In recent years, myocardial regeneration therapy has been the subject of intense research. Several different cell lines and routes of administration have been tested and the main mechanisms of action are known. A substantial amount of data is available not only from the bench, but also from the bedside. However, there are still many unanswered questions about the safety and efficacy of this treatment The future of this therapy is uncertain at present, but it unquestionably has great potential. We await the results of ongoing clinical trials in order to have a clearer view of this field of research.
Gonçalves
Lino M
LM
Clínica Universitária de Cardiologia, Faculdade de Medicina de Coimbra, Coimbra, Portugal. lgoncal@ci.uc.pt
D000818:Animals; D006321:Heart / Q000502:physiology*; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D009203:Myocardial Infarction / Q000601:surgery*; D012038:Regeneration; D033581:Stem Cell Transplantation / Q000009:adverse effects