[Prevention and treatment of biliary complications following orthotopic liver transplantation].
OBJECTIVE
To study the prevention and treatment of biliary complications after orthotopic liver transplantation.


METHODS
Clinical data of 183 recipients who had received liver transplantation between May 1995 and December 2006 were retrospectively analyzed.


RESULTS
Biliary complications occurred in 15 patients (15/183, 8.2%). The incidence for short-term and long-term complication were 6.0% (11/183) and 2.2% (4/183) respectively. No biliary complications was due to hepatic artery thrombosis(HAT). Four cases who received PTC(percutaneous transhepatic cholangiography) with stent insertion,8 cases who received ERCP( endoscopic retrograde cholangiopancreatography) with stent insertion and 1 who received Roux-en-Y choledochojejunostomy for anastomotic stricture were successfully cured. Two cases required relaparotomy died for fungus infection eventually. The mortality due to biliary complications was 1.1%.


CONCLUSIONS
The rapid combined abdominal organ harvesting technique could shorten the ischemia time and ameliorate the injury due to vascular and bile duct variances, which could reduce the incidence of biliary complication. PTC and (or) ERCP combined with stent insertion were main procedure for biliary complications not related to HAT after liver transplantation.
Liu
Yong-feng
YF
Department of General Surgery, First Hospital of China Medical University, Shenyang 110001, China. yfliu@mail.cmu.edu.cn
Li
Gui-chen
GC
Wu
Gang
G
Zhang
Jia-lin
JL
Liu
Shu-rong
SR
Meng
Yi-man
YM
Cheng
Ying
Y
Yang
Lei
L
Sun
Ming-jun
MJ
Zhang
Xi-tong
XT
D000328:Adult; D000368:Aged; D001660:Biliary Tract Diseases / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control / Q000628:therapy; D012189:Retrospective Studies