[Pan-European survey on the undertreatment of hypercholesterolemia in hypolipidemias(Luxembourg)].
Cepheus (Centralized Pan-European survey on the undertreatment of hypercholesterolemia) is an observational centralized study realized in 8 European countries including Luxemburg. The aim was to evaluate the percentage of patients reaching the TJETF and 2004 NCEP ATP III recommendations for LDL-cholesterol. A secondary aim was to identify by questionnaires the determinants of patients and physicians explaining this undertreatment. Data from 706 patients in Luxemburg have shown that only 40.6% of patients and only 17.5% of high risk patients (CVD and diabetes) reach the newest european target values of LDL-cholesterol (post-hoc analysis). 90% of patients had statins prescribed and 9.7% fibrates. 60% of patients had still the same medication at the same dosage at the moment of the study, after at least 3 months treatment with a mean of 6.2 years. 40% of patients said that they forget sometimes their treatment and 13% were convinced that forgetting their tablets more than once a week did not affect their cholesterol level. These disappointing results could be due partly to insufficient dosages, too less adaptation of the treatment and a bad compliance of patients.
Michel
G
G
Service d' Endocrinologie-Diabétologie, Centre Hospitalier de Luxembourg, 4 rue Barblé, L-1210 Luxembourg.
Muller
Ph
P
D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications* / Q000188:drug therapy* / Q000453:epidemiology; D006973:Hypertension / Q000150:complications; D007009:Hypolipoproteinemias / Q000150:complications* / Q000453:epidemiology; D008189:Luxembourg / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology; D008875:Middle Aged; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol