title: "What is it?" A functional MRI and SPECT study of ictal speech in a second language.
abstract: Neuronal networks involved in second language (L2) processing vary between normal subjects. Patients with epilepsy may have ictal speech automatisms in their second language. To delineate the brain systems involved in L2 ictal speech, we combined functional MRI during bilingual tasks and ictal--interictal single-photon emission computed tomography in a patient who presented L2 ictal speech productions. These analyses showed that the networks activated by the seizure and those activated by L2 processing intersected in the right hippocampus. These results may provide some insights both into the pathophysiology of ictal speech and into the brain organization for L2.
authors.affiliation: Department of Neurology, AP-HP, Hôpital de la Pitié-Salpêtrière, IFR 70, Paris, France. vincent.navarro@psl.aphp.fr
authors.forename: Vincent
authors.initials: V
authors.lastname: Navarro
authors.forename: Christine
authors.initials: C
authors.lastname: Delmaire
authors.forename: Valérie
authors.initials: V
authors.lastname: Chauviré
authors.forename: Marie-Odile
authors.initials: MO
authors.lastname: Habert
authors.forename: Rosalie
authors.initials: R
authors.lastname: Footnick
authors.forename: Stéphane
authors.initials: S
authors.lastname: Lehéricy
authors.forename: Michel
authors.initials: M
authors.lastname: Baulac
authors.forename: Christophe
authors.initials: C
authors.lastname: Pallier
authors.forename: Laurent
authors.initials: L
authors.lastname: Cohen
mesh_terms: D000328:Adult; D001332:Automatism / Q000209:etiology; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000503:physiopathology; D001931:Brain Mapping; D004569:Electroencephalography; D004827:Epilepsy / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D019303:Multilingualism; D010100:Oxygen / Q000097:blood; D013060:Speech; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D010100:Oxygen