title: Extramedullary plasmacytoma in the maxillary sinus.
abstract: Extramedullary plasmacytoma is a rare malignant plasma cell tumour. We report an extremely aggressive case of extramedullary plasmacytoma of the right maxillary sinus, which had metastasised to the brain and rib. A 56-year-old man presented with recurrent epistaxis and acute anaemia. Nasendoscopy revealed a medialised medial wall of the right maxilla and a mass occupying the whole nasopharynx. Magnetic resonance imaging revealed a right maxillary tumour with extension to the ipsilateral nasal cavity, nasopharynx, right sphenoid and ethmoidal sinuses. There was an extra-axial brain metastasis. There were metastases to the right parietal region and left eighth rib. Histopathology examination of the maxillary mass revealed abundant plasma cells with kappa-chain restriction. He was planned for four cycles of chemotherapy. Unfortunately, in view of the advanced stage of disease, he succumbed to his disease during the first cycle of chemotherapy.
authors.affiliation: Department of Otorhinolaryngology, Head & Neck Surgery, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.
authors.forename: M A
authors.initials: MA
authors.lastname: Megat Shiraz
authors.forename: Y H
authors.initials: YH
authors.lastname: Jong
authors.forename: S H
authors.initials: SH
authors.lastname: Primuharsa Putra
mesh_terms: D000740:Anemia / Q000150:complications; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging / Q000473:pathology; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009305:Nasopharynx / Q000473:pathology; D009362:Neoplasm Metastasis; D010954:Plasmacytoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
chemical_list: D000970:Antineoplastic Agents