title: [Risk factors and surgical treatment of recurrent gastrointestinal stromal tumor in the rectum].
abstract: OBJECTIVE
  To investigate the risk factors and surgical treatment of recurrent gastrointestinal stromal tumors in the rectum.
  
  
  METHODS
  The clinical data of 24 cases,admitted to our hospital, were analyzed retrospectively. The possible risk factors were tested by chi(2)-test. The resectable rate and recurrent rate of recurrent cases were compared with the first-treated cases.
  
  
  RESULTS
  The tumors with biggest diameter >or=3 cm and high invasive risk had higher recurrent rates (chi(2)=4.874, P=0.027, chi(2)=6.659, P=0.010). The resectable rate of recurrent gastrointestinal stromal tumors in rectum was 64.3% (9/14), which was significantly lower than that of first-treated ones (23/24) (chi(2)=6.618, P=0.010). There was no significant difference of recurrent rate between the recurrent group and the first-treated group (chi(2)=1.459, P>0.05).
  
  
  CONCLUSIONS
  The size and invasive risk of tumor are associated with the recurrent rate of gastrointestinal stromal tumors in rectum. The resectable rate of recurrent gastrointestinal stromal tumors in rectum is significantly lower than that of first-treated ones, but recurrent rates are similar in the 2 groups.
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Yu-xin
authors.initials: YX
authors.lastname: Zhong
authors.forename: Zhi-xiang
authors.initials: ZX
authors.lastname: Zhou
authors.forename: Wei
authors.initials: W
authors.lastname: Pei
authors.forename: Li-ming
authors.initials: LM
authors.lastname: Wang
authors.forename: Fan
authors.initials: F
authors.lastname: Wu
authors.forename: Yong-fu
authors.initials: YF
authors.lastname: Shao
authors.forename: Ping
authors.initials: P
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors