title: Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle.
abstract: This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH12 and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.
authors.affiliation: Universidade do Oeste Paulista-UNOESTE, Pós-gradu ção em Ciência Animal, Presidente Prudente-SP, CEP 19067-175, Brasil. reis.lsls@gmail.com
authors.forename: Luis Souza
authors.initials: LS
authors.lastname: de Souza Reis
authors.forename: Neuza Maria
authors.initials: NM
authors.lastname: Frazatti-Gallina
authors.forename: Rosana
authors.initials: R
authors.lastname: de Lima Paoli
authors.forename: Rogerio
authors.initials: R
authors.lastname: Giuffrida
authors.forename: Avelino
authors.initials: A
authors.lastname: Albas
authors.forename: Eunice
authors.initials: E
authors.lastname: Oba
authors.forename: Paulo Eduardo
authors.initials: PE
authors.lastname: Pardo
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D004306:Dose-Response Relationship, Immunologic; D004334:Drug Administration Schedule; D004347:Drug Interactions; D031168:Matricaria / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D010936:Plant Extracts; D011819:Rabies Vaccines