New cycloartane glycosides from Camptosorus sibiricus Rupr.
Three new cycloartane glycosides were isolated from the whole herbs of Camptosorus sibiricus Rupr. By means of chemical and spectroscopic methods (IR, 1D, and 2D NMR, HR-MS, ESI-MS), the structures were established as (24R)-3beta,7beta,24,25, 30-pentahydroxycycloartane-3-O-beta-D-glucopyranosyl-(1-->4)-[alpha-L-arabinopyranosyl-(1-->2)-beta-D-glucopyranosyl]-24-O-beta-D-glucopyranoside (1), (24R)-3beta,7beta,24,25,30-pentahydroxycycloartane-3-O-beta-D-glucopyranosyl-(1-->4)-[beta-D-galactopyranosyl-(1-->2)-beta-D-glucopyranosyl]-24-O-beta-D-glucopyranoside (2), (24R)-3beta,7beta,24,25,30-pentahydroxycycloartane-30-O-coumaroyl-3-O-beta-D-glucopyranosyl-24-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (3). At the same time, the new compounds were tested for their cytotoxicities in vitro against human tumor cell lines (A375-S2, Hela) using MTT method.
Zhang
Peng
P
Institute of Pharmaceutical Informatics, Zhejiang University in Zijingang Campus, Hangzhou, China.
Cheng
Yi-Yu
YY
Ma
Zhong-Jun
ZJ
D029624:Ferns / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry*
D006027:Glycosides; D014315:Triterpenes; C085352:cycloartane