DNA methylation might be the epigenetic molecular mechanism of different antihypertensive efficacy of metoprolol in beta1-AR gene-directed therapy.
Jiang
Qixia
Q
Yuan
Hong
H
Huang
Zhijun
Z
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D019175:DNA Methylation / Q000187:drug effects / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000235:genetics*; D008790:Metoprolol / Q000008:administration & dosage*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D008790:Metoprolol