title: Thin-flap (sub-Bowman keratomileusis) versus thick-flap laser in situ keratomileusis for moderate to high myopia: case-control analysis.
abstract: OBJECTIVE
  To compare the refractive and visual outcomes of sub-Bowman keratomileusis (SBK) and thick-flap laser in situ keratomileusis (LASIK) for moderate to high myopia and evaluate the effect of corneal flap thickness on outcomes.
  
  
  METHODS
  Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
  
  
  METHODS
  Two studies were performed. In the first study, the refractive and visual outcomes in 33 eyes that had SBK (flap thickness 82 to 120 microm) and 62 eyes that had thick-flap LASIK (flap thickness >or=160) were retrospectively analyzed. Inclusion criteria were spherical equivalent -4.0 to -10.0 diopters (D), astigmatism 3.0 D or less, and follow-up 3 months or more. In the second study, the influence of flap thickness was evaluated. A case-control matched study (21 pairs) that controlled for residual stromal bed (RSB) thickness was performed.
  
  
  RESULTS
  The mean flap thickness was 110.2 microm+/-9.2 (SD) in the SBK group and 179.2+/-19.5 microm in the thick-flap LASIK group. There were no significant differences in visual outcomes. In the second study with equivalent RSB thickness, case-control matched comparisons between SBK (mean 108.6+/-8.0 microm) and thick-flap LASIK (mean 165.7+/-12.6 microm) showed no differences in preoperative and postoperative refractive and visual outcomes. Comparison of the intended versus achieved correction showed no significant differences between the 2 groups.
  
  
  CONCLUSIONS
  Retrospective analyses showed that the safety, efficacy, and predictability of SBK were similar to those of conventional thick-flap LASIK in corneas with equivalent RSB thickness.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois 60612, USA. dazar@uic.edu
authors.forename: Dimitri T
authors.initials: DT
authors.lastname: Azar
authors.forename: Ramon C
authors.initials: RC
authors.lastname: Ghanem
authors.forename: Jose
authors.initials: J
authors.lastname: de la Cruz
authors.forename: Joelle A
authors.initials: JA
authors.lastname: Hallak
authors.forename: Takashi
authors.initials: T
authors.lastname: Kojima
authors.forename: Faisal M
authors.initials: FM
authors.lastname: Al-Tobaigy
authors.forename: Sandeep
authors.initials: S
authors.lastname: Jain
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003319:Corneal Stroma / Q000473:pathology; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*