title: Severe pneumonia with Leptotrichia sp. detected predominantly in bronchoalveolar lavage fluid by use of 16S rRNA gene sequencing analysis.
abstract: We present the first case of severe pneumonia possibly caused by Leptotrichia species with oral bacteria. This was found in a healthy but elderly subject whose bronchoalveolar lavage fluid was analyzed by 16S rRNA gene sequencing analysis. The combination of this method and microscopic observation provided useful information for diagnosis and treatment.
authors.affiliation: Department of Respiratory Disease, University of Occupational and Environmental Health, Fukuoka, Japan.
authors.forename: Toshinori
authors.initials: T
authors.lastname: Kawanami
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fukuda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yatera
authors.forename: Takashi
authors.initials: T
authors.lastname: Kido
authors.forename: Chiharu
authors.initials: C
authors.lastname: Yoshii
authors.forename: Hatsumi
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Kido
mesh_terms: D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D045825:Fusobacteriaceae Infections / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D045183:Leptotrichia / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000382:microbiology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D013902:Radiography, Thoracic; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S