title: Primary cutaneous B-cell lymphoma, leg type restricted to the subcutaneous fat arising in a patient with dermatomyositis.
abstract: Until now, cutaneous lymphoma limited to the subcutaneous fat has been described as being derived only from T cells. Subcutaneous panniculitis-like T-cell lymphoma has been reported as a rare, postthymic neoplasm with various associations, including dermatomyositis. Furthermore, primary cutaneous B-cell lymphoma of the leg is defined by a diffuse dermal infiltrate of neoplastic B cells with extension to both the papillary dermis and the subcutaneous fat. We report a case of a patient with dermatomyositis who developed a cutaneous lymphoma of B-cell origin restricted to the subcutis, the first of its kind reported in the literature. This malignancy spared the dermis and epidermis, and we suggest that this is a unique variant of primary cutaneous B-cell lymphoma of the leg.
authors.affiliation: Division of Dermatology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN 38104, USA. alevy@utmem.edu
authors.forename: Alan
authors.initials: A
authors.lastname: Levy
authors.forename: M Barry
authors.initials: MB
authors.lastname: Randall
authors.forename: Terri
authors.initials: T
authors.lastname: Henson
mesh_terms: D000368:Aged; D003882:Dermatomyositis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007866:Leg; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D050151:Subcutaneous Fat / Q000473:pathology*