title: Periodic fever as the only presenting symptom of multiple myeloma in a young man.
abstract: We describe a 30-year-old male patient presenting with periodic fever. The patient underwent a series of laboratory tests, X-rays and CT scans. Quantitative immunoglobulin showed IgG 3210.00 mg/dl, IgA 20.00 mg/dl and IgM 27.70 mg/dl. Serum protein electrophoresis revealed a peak with a broad gamma band. Immunofixation revealed an immunoglobulin G -lambda monoclonal component. A bone marrow biopsy established the presence of multiple myeloma. To our knowledge, a periodic 24-hour-lasting fever as the only presenting symptom of multiple myeloma has never been reported.
authors.forename: C
authors.initials: C
authors.lastname: Trakatelli
authors.forename: E
authors.initials: E
authors.lastname: Kintiraki
authors.forename: J
authors.initials: J
authors.lastname: Koratzis
authors.forename: L
authors.initials: L
authors.lastname: Gamvrili
authors.forename: V
authors.initials: V
authors.lastname: Kotsis
authors.forename: M
authors.initials: M
authors.lastname: Sion
mesh_terms: D000328:Adult; D005334:Fever / Q000209:etiology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007146:Immunoglobulin lambda-Chains / Q000097:blood; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D010507:Periodicity; D012008:Recurrence
chemical_list: D007074:Immunoglobulin G; D007146:Immunoglobulin lambda-Chains