title: [The Macklin effect in the etiology for pneumediastinum in chest trauma].
abstract: This case report has the scope to review the etiology and pathophysiology of pneumomediastinum in severe blunt trauma, with a special interest to its more frequent origin: the Macklin effect. The Macklin effect is a pathophysiologic process characterized by the blunt traumatic alveolar ruptures, air dissection along bronchovascular sheaths, with the formation of blunt pulmonary interstitial emphysema, radiologic marker, until the formation of a pneumomediastinum. Its premature diagnostic acknowledgment is important in the managing of the blunt chest trauma.
authors.affiliation: UOC Anestesia e Rianimazione, Ospedale Umberto I, Nocera Inferiore (Salerno). salvatore.palmese@libero.it
authors.forename: Salvatore
authors.initials: S
authors.lastname: Palmese
authors.forename: Domenico
authors.initials: D
authors.lastname: Carbone
authors.forename: Raffaele
authors.initials: R
authors.lastname: Muoio
authors.forename: Daniele
authors.initials: D
authors.lastname: Scarano
authors.forename: Italia
authors.initials: I
authors.lastname: Odierna
authors.forename: Andrea C
authors.initials: AC
authors.lastname: Scibilia
authors.forename: Alfonso
authors.initials: A
authors.lastname: Natale
mesh_terms: D006801:Humans; D008297:Male; D008478:Mediastinal Emphysema / Q000000981:diagnostic imaging / Q000209:etiology*; D013898:Thoracic Injuries / Q000150:complications*; D014057:Tomography, X-Ray Computed; D055815:Young Adult