title: Transitory increase in middle cerebral artery peak systolic velocity of recipient twins after fetoscopic laser photocoagulation for twin-twin transfusion syndrome.
abstract: OBJECTIVE
  It was the aim of this study to elucidate the clinical features of recipient twins with increased middle cerebral artery peak systolic velocity (MCA-PSV) after fetoscopic laser photocoagulation (FLP) for twin-twin transfusion syndrome.
  
  
  METHODS
  Serial Doppler velocimetry of the MCA was performed in 30 recipient twins before and after FLP. Clinical data and perinatal outcome were compared between cases with and without increased MCA-PSV.
  
  
  RESULTS
  Increased MCA-PSV was observed in 7 recipients (23.3%) within 14 days after FLP. MCA-PSV gradually decreased to <1.5 multiples of median in 6 recipients; however, 1 patient resulted in fetal demise subsequent to the demise of the co-twin. The incidences of fetal and neonatal demise and neurological morbidity were similar. No recipient was diagnosed as anemic at birth.
  
  
  CONCLUSIONS
  The increase in MCA-PSV in recipients following FLP appeared to be generally transitory; this differs from twin anemia-polycythemia sequence.
authors.affiliation: Division of Perinatology, Fetal Diagnosis and Therapy, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan. keisui@sis.seirei.or.jp
authors.forename: Keisuke
authors.initials: K
authors.lastname: Ishii
authors.forename: Takeshi
authors.initials: T
authors.lastname: Murakoshi
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Matsushita
authors.forename: Takashi
authors.initials: T
authors.lastname: Sinno
authors.forename: Hiroo
authors.initials: H
authors.lastname: Naruse
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Torii
mesh_terms: D000740:Anemia / Q000401:mortality; D001783:Blood Flow Velocity; D005260:Female; D005313:Fetal Death; D005330:Fetofetal Transfusion / Q000000981:diagnostic imaging* / Q000401:mortality / Q000601:surgery*; D005332:Fetoscopy; D006801:Humans; D017075:Laser Coagulation; D020768:Middle Cerebral Artery / Q000502:physiology*; D009017:Morbidity; D011086:Polycythemia / Q000401:mortality; D011237:Predictive Value of Tests; D011247:Pregnancy; D014427:Twins; D016216:Ultrasonography, Prenatal