title: Nosocomial bloodstream infections in children: an 8-year experience at a tertiary-care hospital in Finland.
abstract: Laboratory-based surveillance at a Finnish paediatric tertiary-care centre during the period 1999-2006 identified 739 nosocomial bloodstream infections (BSIs) (1.6 BSIs/1000 patient-days). High rates were detected among haematology patients (4.9 BSIs/1000 patient-days) and neonatology patients (3.2 BSIs/1000 patient-days). Most BSIs (95%) were primary infections, and 75% of those were associated with a central line. The most common pathogens were coagulase-negative staphylococci (52%), Staphylococcus aureus (7%) and Candida species (6%). The overall mortality rate within 7 days after the first positive blood culture was 3%. Those who died were more likely to have been admitted to an intensive-care unit or to have undergone surgery.
authors.affiliation: Department of Infectious Disease Epidemiology and Control, National Public Health Institute (KTL), Helsinki, Finland. emmi.sarvikivi@ktl.fi
authors.forename: E
authors.initials: E
authors.lastname: Sarvikivi
authors.forename: O
authors.initials: O
authors.lastname: Lyytikäinen
authors.forename: M
authors.initials: M
authors.lastname: Vaara
authors.forename: H
authors.initials: H
authors.lastname: Saxén
mesh_terms: D000293:Adolescent; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D001769:Blood / Q000382:microbiology; D002648:Child; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D007362:Intensive Care Units; D009181:Mycoses / Q000453:epidemiology* / Q000382:microbiology; D015995:Prevalence; D012307:Risk Factors; D018805:Sepsis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality