title: Krypton yellow laser for the treatment of macular hole in high myopia without retinal detachment.
abstract: OBJECTIVE
  To evaluate the prophylactic effect of krypton yellow laser for the treatment of macular holes in high myopic eyes in order to reduce the risk of retinal detachment.
  
  
  METHODS
  Twenty-seven eyes of 27 patients with high myopia and macular holes were randomly assigned to two groups. Fifteen patients (group A, 15 eyes) were subject to laser photocoagulation around the hole margin along with an oral placebo (vitamin B1), while 12 patients (group B, 12 eyes) were only given the oral placebo (vitamin B1). The incident rate of retinal detachment due to macular hole and the mean best-corrected visual acuity of the two groups before and after treatment were measured. The data were statistically tested by X2 test and Student's t test.
  
  
  RESULTS
  The incident rates of retina1 detachment in group A and group B were 20%(3/15) and 58.3%(7/12), respectively (X2=4.201, P0.05). The mean BCVA of group B on the initial examination was 24/200, while the mean BCVA at the final follow-up was 30/200 (P>0.05). No significant difference in initial visual acuity (P>0.05) or final visual acuity (P>0.05) was found between the two groups.
  
  
  CONCLUSIONS
  Krypton yellow laser photocoagulation could reduce the incidence of retinal detachment due to a macular hole in high myopia with acceptable functional results in this study.
authors.affiliation: Department of Ophthalmology, Second AffiliatedHospital, Second Military Medical University, Shanghai200003, China.
authors.forename: Ji-Ping
authors.initials: JP
authors.lastname: Cai
authors.forename: Jin-Wei
authors.initials: JW
authors.lastname: Cheng
authors.forename: Xiao-Ye
authors.initials: XY
authors.lastname: Ma
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Li
authors.forename: You
authors.initials: Y
authors.lastname: Li
authors.forename: Rui-Li
authors.initials: RL
authors.lastname: Wei
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007726:Krypton; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D011446:Prospective Studies; D012163:Retinal Detachment / Q000209:etiology / Q000517:prevention & control*; D012167:Retinal Perforations / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D007726:Krypton