title: Papillary thyroid carcinoma and familial adenomatous polyposis of the colon.
abstract: OBJECTIVE
  Case report and limited review of the literature on the topic of papillary thyroid carcinoma and familial adenomatous polyposis and its genetic associations.
  
  
  METHODS
  A patient with multiple prior surgeries for colonic polyps, abdominal perineal resection for colorectal cancer, and wedge resection for metastatic adenocarcinoma (consistent with rectal primary) presented with a thyroid mass. Fine-needle aspiration demonstrated papillary thyroid carcinoma.
  
  
  RESULTS
  The patient underwent total thyroidectomy. Pathologic examination revealed the cribriform-morular variant of papillary carcinoma that has been reported in patients with familial adenomatous polyposis.
  
  
  CONCLUSIONS
  Cribriform-morular variant of papillary thyroid carcinoma is an uncommon diagnosis known to be associated with familial adenomatous polyposis. Although the incidence is rare, this diagnosis should raise the clinician's suspicions to recommend both colorectal screening and genetic counseling for family members.
authors.affiliation: Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson, MS 39216-4505, USA. kdonnellan@ent.umsmed.edu
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Donnellan
authors.forename: Steven A
authors.initials: SA
authors.lastname: Bigler
authors.forename: Richard O
authors.initials: RO
authors.lastname: Wein
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D001707:Biopsy, Needle; D002291:Carcinoma, Papillary / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011300:Preoperative Care; D018570:Risk Assessment; D013964:Thyroid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D013965:Thyroidectomy / Q000379:methods*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome