Nutrition: its role in bone health.
At a given age, bone mass is determined by the amount of bone accumulated at the end of skeletal growth (the so-called peak bone mass), and by the amount of bone lost subsequently. Nutritional intake is an environmental factor that influences both bone capital accumulation, which is fully achieved by the end of the second decade of life, and bone loss, which occurs during the second half of existence. Nutrients may act directly by modifying bone turnover, or indirectly via changes in calciotropic hormone secretion. The study of the association between nutrition and a bone phenotypic expression may provide inconsistent results, in part because of the low accuracy and reproducibility of the various tools used to assess dietary intakes. Sufficient dietary calcium and protein are necessary for bone health during growth as well as in the elderly.
Rizzoli
René
R
Division of Bone Diseases, WHO Collaborating Center for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Geneva 14, Switzerland. rene.rizzoli@medecine.unige.ch
D016723:Bone Remodeling / Q000502:physiology; D001842:Bone and Bones / Q000378:metabolism*; D002136:Calcium, Dietary / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D050723:Fractures, Bone / Q000517:prevention & control; D006801:Humans; D008297:Male; D009751:Nutritional Requirements; D014807:Vitamin D / Q000008:administration & dosage
D002136:Calcium, Dietary; D004044:Dietary Proteins; D014807:Vitamin D