Minutes from the round table held in Paris on July 6, 2007: 'Contribution of modelling in the paediatric drug development'.
A symposium called "Contribution of modelling in the paediatric drug development" was organized at Paris on July 5-6, 2007 under the auspices of INSERM. The following issues were highlighted and discussed by the participants at the end of the meeting during a round table: *What is the place of modelling at a preclinical stage in the paediatric development? *What is the place of modelling at a clinical stage in the paediatric development? *What are the requirements for an evaluation based on modelling? *What are the recommendations and guidelines need to be established to facilitate the use of modelling techniques in paediatrics? This paper summarizes the discussion around these four questions.
Laveille
Christian
C
Exprimo NV, Mechelen, Belgium. christian.laveille@exprimo.com
Vis
Peter
P
D002648:Child; D002657:Child Development; D002986:Clinical Trials as Topic; D003198:Computer Simulation; D004334:Drug Administration Schedule; D055808:Drug Discovery; D054796:Drug Dosage Calculations; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008954:Models, Biological; D010372:Pediatrics / Q000379:methods*; D010599:Pharmacokinetics; D017410:Practice Guidelines as Topic