Antibacterial activity of chitooligosaccharides.
The aim of this study was to investigate the antibacterial activity of chitooligosaccharide, prepared by partial acid hydrolysis of chitosan, and of an aminoglycosylated derivative, prepared by reductive alkylation of the chitooligosaccharide, against E. coli and S. aureus.
Lillo
Luis
L
Departamento Ciencias Básicas, Facultad de Ciencias, Universidad del Bío-Bío, Chillán, Chile. llillo@ubiobio.cl
Alarcón
Julio
J
Cabello
Gerardo
G
Céspedes
Carlos
C
Caro
Claudia
C
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002686:Chitin / Q000494:pharmacology*; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D005944:Glucosamine / Q000737:chemistry; D006868:Hydrolysis; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D009844:Oligosaccharides / Q000737:chemistry / Q000494:pharmacology*; D037121:Plant Lectins / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D009844:Oligosaccharides; D037121:Plant Lectins; D002686:Chitin; D048271:Chitosan; D005944:Glucosamine