title: Pd-catalyzed deoxygenation of mandelate esters.
abstract: A new approach to the synthesis of phenylacetic acids and esters has been developed via the palladium-catalyzed deoxygenation of mandelate esters.
authors.affiliation: Chemical Process R&D, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA. milne@amgen.com
authors.forename: Jacqueline E
authors.initials: JE
authors.lastname: Milne
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Murry
authors.forename: Anthony
authors.initials: A
authors.lastname: King
authors.forename: Robert D
authors.initials: RD
authors.lastname: Larsen
mesh_terms: D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry*; D008333:Mandelic Acids / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010648:Phenylacetates / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004952:Esters; D008333:Mandelic Acids; D009942:Organometallic Compounds; D010648:Phenylacetates; D010165:Palladium; C025136:phenylacetic acid; C037938:mandelic acid; D010100:Oxygen