title: Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses.
abstract: Pus samples were prospectively collected from patients with Staphylococcus aureus skin infections and tested for Panton-Valentine leukocidin (PVL). PVL was detected at concentrations that were toxic for rabbit skin in all specimens from patients infected with strains harbouring PVL genes.
authors.affiliation: INSERM U851, Université de Lyon, Centre National de référence des Staphylocoques, Faculté Laennec, Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Badiou
authors.forename: O
authors.initials: O
authors.lastname: Dumitrescu
authors.forename: M
authors.initials: M
authors.lastname: Croze
authors.forename: Y
authors.initials: Y
authors.lastname: Gillet
authors.forename: B
authors.initials: B
authors.lastname: Dohin
authors.forename: D H
authors.initials: DH
authors.lastname: Slayman
authors.forename: B
authors.initials: B
authors.lastname: Allaouchiche
authors.forename: J
authors.initials: J
authors.lastname: Etienne
authors.forename: F
authors.initials: F
authors.lastname: Vandenesch
authors.forename: G
authors.initials: G
authors.lastname: Lina
mesh_terms: D000038:Abscess / Q000382:microbiology* / Q000473:pathology*; D001427:Bacterial Toxins / Q000032:analysis*; D005098:Exotoxins / Q000032:analysis*; D006801:Humans; D007956:Leukocidins / Q000032:analysis*; D013207:Staphylococcal Skin Infections / Q000473:pathology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D013492:Suppuration / Q000382:microbiology
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin