Azotemia in cats with feline hypertrophic cardiomyopathy: prevalence and relationships with echocardiographic variables.
OBJECTIVE
The prevalence of renal azotemia in cats with acquired heart disease is not well documented. The aims of this study were therefore (1) to determine the prevalence of azotemia within a hospital population of cats with hypertrophic cardiomyopathy (HCM), and (2) to evaluate the relationship between echocardiographic variables and plasma urea and creatinine.


METHODS
134 client-owned cats were retrospectively studied including 102 cats with HCM and 32 control cats. A complete physical examination, electrocardiography, systolic arterial blood pressure measurement, thoracic radiographs, and echocardiography were performed. Plasma creatinine and urea were determined in all cats. The animal was considered azotemic if plasma creatinine was >1.8 mg/dL and/or urea >65 mg/dL (i.e. BUN> 30 mg/dL).


RESULTS
The prevalence of azotemia was lower in control cats (25.0%) than in cats with HCM (58.8%) (P=0.003). No significant differences in plasma urea and creatinine were observed between the HCM and control cats. There was no effect of plasma creatinine and urea on conventional echocardiographic variables in cats with HCM.


CONCLUSIONS
Azotemia is a frequent finding in cats with HCM but is not dependent on echocardiographic variables.
Gouni
Vassiliki
V
Unité de Cardiologie d'Alfort, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort Cedex, France.
Chetboul
Valérie
V
Pouchelon
Jean-Louis
JL
Carlos Sampedrano
Carolina
C
Maurey
Christelle
C
Lefebvre
Hervé P
HP
D000818:Animals; D053099:Azotemia / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D001794:Blood Pressure; D002312:Cardiomyopathy, Hypertrophic / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D016022:Case-Control Studies; D002371:Cat Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D002415:Cats; D015897:Comorbidity; D003404:Creatinine / Q000097:blood*; D004452:Echocardiography / Q000662:veterinary*; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology / Q000662:veterinary; D008297:Male; D010808:Physical Examination / Q000662:veterinary; D015995:Prevalence; D013902:Radiography, Thoracic / Q000662:veterinary; D012189:Retrospective Studies; D014508:Urea / Q000097:blood*
D014508:Urea; D003404:Creatinine