title: Osteosarcoma of the larynx: a case report.
abstract: BACKGROUND
  We add a new rare illustrative case of osteosarcoma of the larynx to the literature.
  
  
  METHODS
  The patient (man; 56 years old) first underwent several biopsies, followed in the end by a total laryngectomy. Diagnosis was histological. The patient developed regional and distant metastases and died of disease after 3 months from surgery.
  
  
  CONCLUSIONS
  Osteosarcoma of the larynx is a rare and aggressive tumour with a poor long-term prognosis. The preferred treatment for this tumour is aggressive surgery.To perform a diagnosis we must be in presence of osteoid or of neoplastic osseous tissue directly produced by the neoplastic cells.
authors.affiliation: Department of Otolaryngology, Hospital "San Giovanni di Dio e Ruggi d'Aragona", Via San Leonardo, Salerno, Italy. giampieromottola@hotmail.com.
authors.forename: Giampiero
authors.initials: G
authors.lastname: Mottola
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Cascone
authors.forename: Matteo
authors.initials: M
authors.lastname: Cavaliere
authors.forename: Basilio
authors.initials: B
authors.lastname: Angrisani
authors.forename: Gabriella
authors.initials: G
authors.lastname: Fiorillo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Parente
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Volino
authors.forename: Maurizio
authors.initials: M
authors.lastname: Iemma