title: [Experimental substantiation of the new method of hemostasis].
abstract: The article provides the results of experimental welding occlusion of arterial and venous vessels 2-12 mm in diameter, including 998 bench tests of resected animal vessels, 256 bench tests of resected human vessels, and also experiments involving 42 live animals (pigs). During the above-mentioned tests 748 vessel obturations were performed. Manual regimen of welding enables the leakproof obturation of the vessel in 66.4% of animals, the result was instable in 22% of cases, no obturation was achieved in 11.6%. Selecting the optimal automatic regimen, we obtained the best results during whelming with the use of the program N.6. The mean strength of the suture obtained in 98.2% of cases was 91,066.7 +/- 215.20 mm Hg. The instable outcome of welding in 1.8% of cases of the use of program N 6 was the result of the use of different welding instruments. The best results (1324 +/- 258) mm Hg were obtained when the electrodes of the welding clamp were compressed at one peg and the force of compression was 91.9 +/- 0.2) MPa. We have established that the short-term impact of increased temperature (from (56 +/- 1.9) to (81 +/- 2.7) degrees C enables denaturation and coagulation of protein molecules, which results in welding connection without coagulation necrosis.
authors.forename: O Ie
authors.initials: OIe
authors.lastname: Shved
authors.forename: S Ie
authors.initials: SIe
authors.lastname: Podpriatov
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Hupalo
authors.forename: O V
authors.initials: OV
authors.lastname: Lebedev
authors.forename: A H
authors.initials: AH
authors.lastname: Dubko
mesh_terms: D000818:Animals; D001158:Arteries; D001831:Body Temperature; D004564:Electrocoagulation / Q000379:methods*; D006487:Hemostasis / Q000502:physiology*; D014680:Veins