title: Therapeutic prostate cancer vaccines: a review of the latest developments.
abstract: Therapeutic cancer vaccines are well-tolerated immunotherapy modalities designed to activate the immune system to kill cancer cells without a significant effect on healthy cells. An improved understanding of tumor immunology has led to improved strategies in vaccine development, which in turn have resulted in improved outcomes. This review discusses different types of cancer vaccines, with a focus on prostate cancer vaccines because of the high prevalence of prostate cancer and the wide variety of approaches used in prostate cancer immunotherapy.
authors.affiliation: National Cancer Institute, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Drive, Building 10, Room 8B09, MSC 1750, Bethesda, MD 20892-1750, USA.
authors.forename: Mahsa
authors.initials: M
authors.lastname: Mohebtash
authors.forename: Ravi A
authors.initials: RA
authors.lastname: Madan
authors.forename: James L
authors.initials: JL
authors.lastname: Gulley
authors.forename: Philip M
authors.initials: PM
authors.lastname: Arlen
mesh_terms: D019496:Cancer Vaccines / Q000276:immunology / Q000627:therapeutic use*; D006801:Humans; D007167:Immunotherapy / Q000379:methods* / Q000639:trends; D008297:Male; D011471:Prostatic Neoplasms / Q000276:immunology / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D019496:Cancer Vaccines