[Acute Q fever, antiphopholipid antibodies and renal artery thrombosis: case report and literature review].
BACKGROUND
Antiphospholipid antibodies (aPL) can be associated with numerous infectious and particularly Q fever. Data on the pathogenicity of aPL in the course of acute Q fever are scarce.


METHODS
We report the case an acute Coxiella burnetii infection associated with clinical and biological manifestations of the aPL syndrome, including a renal infarction. Along with antibiotic treatment, anticoagulation and intravenous immunoglobulins, the clinical outcome was favourable. Antiphospholipid antibodies and Q fever antibody titers had a closely related evolution.


CONCLUSIONS
Arterial thrombosis associated with Q fever and aPL is exceptional. The nosology and potential mechanisms are discussed.
Pers
Y-M
YM
Département de médecine interne, Centre hospitalier de Béziers, 34525 Béziers cedex, France.
Puygrenier
M
M
Borlot
F
F
Simorre
B
B
Barazer
I
I
Oziol
E
E
Reny
J-L
JL
D000208:Acute Disease; D000328:Adult; D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D011778:Q Fever / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012078:Renal Artery Obstruction / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants; D016756:Immunoglobulins, Intravenous