title: A severe case of intracranial hemorrhage due to alloimmune thrombocytopenia.
abstract: Alloimmune thrombocytopenia (AIT) is an important cause of intrauterine hemorrhagic lesions that result from platelet-antigen incompatibility between mother and foetus. Foetal platelets are destroyed by cross-reactive maternal antibodies that cross the placenta. The most serious complication of AIT is foetal intracranial bleeding that may eventually result in intrauterine death or severe neurological impairments.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Catholic University of the Sacred Heart, Rome, Italy. frnchr@libero.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Cota
authors.forename: Antonio Alberto
authors.initials: AA
authors.lastname: Zuppa
authors.forename: Rita
authors.initials: R
authors.lastname: Luciano
authors.forename: Francesca
authors.initials: F
authors.lastname: Gallini
authors.forename: Immacolata
authors.initials: I
authors.lastname: Savarese
authors.forename: Giovanni
authors.initials: G
authors.lastname: Alighieri
authors.forename: Claudia
authors.initials: C
authors.lastname: Orchi
authors.forename: Costantino
authors.initials: C
authors.lastname: Romagnoli
mesh_terms: D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging / Q000209:etiology*; D011247:Pregnancy; D054098:Thrombocytopenia, Neonatal Alloimmune / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal