title: A gene cluster in Agrobacterium vitis homologous to polyketide synthase operons is associated with grape necrosis and hypersensitive response induction on tobacco.
abstract: Here, we identify a cluster of eight genes on chromosome 2 of Agrobacterium vitis that is associated with the ability of the bacterium to cause a hypersensitive response on tobacco and a necrosis of grape shoot explants. Three of these genes share a high level of structural and sequence similarity to clusters of genes in other bacteria that encode the enzymes for biosynthesis of polyketides and long-chain polyunsaturated fatty acids. No similar gene clusters were discovered in sequenced genomes of other members of Rhizobiales.
authors.affiliation: Biology Department, Hobart and William Smith Colleges, Geneva, NY, USA.
authors.forename: Sigrid A
authors.initials: SA
authors.lastname: Carle
authors.forename: Guixia
authors.initials: G
authors.lastname: Hao
authors.forename: Desen
authors.initials: D
authors.lastname: Zheng
authors.forename: Tamira
authors.initials: T
authors.lastname: Sanni-Sanoussi
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Talarico
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Hilton
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Burr
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D004251:DNA Transposable Elements; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005810:Multigene Family; D016297:Mutagenesis, Site-Directed; D009876:Operon; D010935:Plant Diseases / Q000382:microbiology*; D048630:Polyketide Synthases / Q000235:genetics*; D012231:Rhizobium / Q000201:enzymology / Q000235:genetics / Q000472:pathogenicity*; D014026:Nicotiana / Q000382:microbiology*; D027843:Vitis / Q000382:microbiology*
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D005231:Fatty Acids, Unsaturated; D048630:Polyketide Synthases