title: Current and fluctuation in a two-state stochastic system under nonadiabatic periodic perturbation.
abstract: We calculate a current and its fluctuation in a two-state stochastic system under a periodic perturbation. The system could be interpreted as a channel on a cell surface or a single Michaelis-Menten catalyzing enzyme. It has been shown that the periodic perturbation induces a so-called pump current, and the pump current and its fluctuation are calculated with the aid of the geometrical phase interpretation. We give a simple calculation recipe for the statistics of the current, especially in a nonadiabatic case. The calculation scheme is based on the nonadiabatic geometrical phase interpretation. Using the Floquet theory, the total current and its fluctuation are calculated, and it is revealed that the average of the current shows a stochastic-resonance-like behavior. In contrast, the fluctuation of the current does not show such behavior.
authors.affiliation: Institute for Solid State Physics, University of Tokyo, Kashiwa-shi, Chiba, Japan. ohkubo@issp.u-tokyo.ac.jp
authors.forename: Jun
authors.initials: J
authors.lastname: Ohkubo
mesh_terms: D004798:Enzymes / Q000737:chemistry / Q000378:metabolism; D007473:Ion Channels / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological; D008956:Models, Chemical; D013269:Stochastic Processes
chemical_list: D004798:Enzymes; D007473:Ion Channels