Mesenchymal stem cells engineered to overexpress stem cell factor improve cardiac function but have malignant potential.
Fazel
Shafie S
SS
Division of Cardiac Surgery, Department of Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Angoulvant
Denis
D
Butany
Jagdish
J
Weisel
Richard D
RD
Li
Ren-Ke
RK
D000818:Animals; D002471:Cell Transformation, Neoplastic; D006338:Heart Neoplasms / Q000209:etiology*; D045164:Mesenchymal Stem Cell Transplantation / Q000009:adverse effects*; D051379:Mice; D009203:Myocardial Infarction / Q000628:therapy; D019089:Stem Cell Factor / Q000032:analysis*
D019089:Stem Cell Factor