title: African swine fever virus isolate, Georgia, 2007.
abstract: African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.
authors.affiliation: Institute for Animal Health, Pirbright, UK.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Rowlands
authors.forename: Vincent
authors.initials: V
authors.lastname: Michaud
authors.forename: Livio
authors.initials: L
authors.lastname: Heath
authors.forename: Geoff
authors.initials: G
authors.lastname: Hutchings
authors.forename: Chris
authors.initials: C
authors.lastname: Oura
authors.forename: Wilna
authors.initials: W
authors.lastname: Vosloo
authors.forename: Rahana
authors.initials: R
authors.lastname: Dwarka
authors.forename: Tinatin
authors.initials: T
authors.lastname: Onashvili
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Albina
authors.forename: Linda K
authors.initials: LK
authors.lastname: Dixon
mesh_terms: D000357:African Swine Fever / Q000453:epidemiology* / Q000821:virology; D000358:African Swine Fever Virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D036022:Capsid Proteins / Q000235:genetics; D004196:Disease Outbreaks; D005838:Genotype; D005846:Georgia (Republic) / Q000453:epidemiology; D008969:Molecular Sequence Data; D010750:Phosphoproteins / Q000235:genetics; D017422:Sequence Analysis, DNA; D034421:Sus scrofa / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics; D015678:Viral Structural Proteins / Q000235:genetics
chemical_list: D036022:Capsid Proteins; D010750:Phosphoproteins; D014764:Viral Proteins; D015678:Viral Structural Proteins; C063745:capsid protein p72, African swine fever virus; C093921:p54 protein, African swine fever virus; C074960:P30 protein, African Swine Fever Virus