title: Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography.
abstract: OBJECTIVE
  The aim of this study was to evaluate the clinical capability of three-dimensional (3D) perfusion imaging of hepatocellular carcinoma (HCC) by performing dynamic scanning using a 256-slice multidetector-row CT (MDCT) scanner.
  
  
  METHODS
  Two patients with HCC were examined in this study. They were scheduled to undergo transcatheter arterial infusion therapy using an arterial infusion reservoir system. The CT system used was a newly developed prototype scanner of 256-slice MDCT. Dynamic CT scanning was performed with intraarterial injection via the reservoir route, and perfusion analysis was done based on the 3D data.
  
  
  RESULTS
  The blood flow volume per unit volume in the tumors was significantly increased compared with that in normal hepatic parenchyma. Using a 3D workstation, 3D perfusion images could be displayed by fusing CT images with perfusion images about blood flow volume.
  
  
  CONCLUSIONS
  Three-dimensional perfusion images, which enable 3D evaluation of perfusion in HCCs, can be generated using 256-slice MDCT.
authors.affiliation: Division of Radiology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan. takobaya@east.ncc.go.jp
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hayashi
authors.forename: Shintaro
authors.initials: S
authors.lastname: Funabasama
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Tsukagoshi
authors.forename: Manabu
authors.initials: M
authors.lastname: Minami
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Moriyama
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011856:Radiographic Image Enhancement / Q000379:methods; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*