title: Marchiafava-Bignami disease.
abstract: Marchiafava- Bignami disease is the symmetrical demyelination of the middle portion of the corpus callosum observed in people with chronic alcoholism. We report two male patients who had history of chronic alcoholism, different clinical presentation and MRI findings consistent with the diagnosis of Marchiafava-Bignami disease.
authors.affiliation: Department of Medicine, Indira Gandhi Medical College, Shimla-171001 (H.P.).
authors.forename: S
authors.initials: S
authors.lastname: Raina
authors.forename: D M
authors.initials: DM
authors.lastname: Mahesh
authors.forename: J
authors.initials: J
authors.lastname: Mahajan
authors.forename: S S
authors.initials: SS
authors.lastname: Kaushal
authors.forename: D
authors.initials: D
authors.lastname: Gupta
authors.forename: D S
authors.initials: DS
authors.lastname: Dhiman
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications* / Q000503:physiopathology; D003337:Corpus Callosum / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D054319:Marchiafava-Bignami Disease / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D010291:Paresis; D018458:Persistent Vegetative State; D012307:Risk Factors; D013831:Thiamine / Q000627:therapeutic use; D014803:Vitamin B Complex / Q000627:therapeutic use
chemical_list: D014803:Vitamin B Complex; D013831:Thiamine