A gene cluster in Agrobacterium vitis homologous to polyketide synthase operons is associated with grape necrosis and hypersensitive response induction on tobacco.
Here, we identify a cluster of eight genes on chromosome 2 of Agrobacterium vitis that is associated with the ability of the bacterium to cause a hypersensitive response on tobacco and a necrosis of grape shoot explants. Three of these genes share a high level of structural and sequence similarity to clusters of genes in other bacteria that encode the enzymes for biosynthesis of polyketides and long-chain polyunsaturated fatty acids. No similar gene clusters were discovered in sequenced genomes of other members of Rhizobiales.
Carle
Sigrid A
SA
Biology Department, Hobart and William Smith Colleges, Geneva, NY, USA.
Hao
Guixia
G
Zheng
Desen
D
Sanni-Sanoussi
Tamira
T
Talarico
Michael J
MJ
Hilton
Joshua S
JS
Burr
Thomas J
TJ
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D004251:DNA Transposable Elements; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005810:Multigene Family; D016297:Mutagenesis, Site-Directed; D009876:Operon; D010935:Plant Diseases / Q000382:microbiology*; D048630:Polyketide Synthases / Q000235:genetics*; D012231:Rhizobium / Q000201:enzymology / Q000235:genetics / Q000472:pathogenicity*; D014026:Nicotiana / Q000382:microbiology*; D027843:Vitis / Q000382:microbiology*
D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D005231:Fatty Acids, Unsaturated; D048630:Polyketide Synthases