title: [Unexpected focal bowel 18-FDG uptake sites: should they be systematically investigated?].
abstract: The purpose of the present study was to retrospectively evaluate the nature and significance of unexpected focal 18-FDG uptake localized by PET/CT within the intestinal tract. Methods. The data of 4,033 PET/CT were retrospectively reviewed. One hundred and eighty PET/CT showed unexpected focal uptakes (patients with known intestinal neoplasia were excluded). Among them, 42 patients corresponding to 47 focal uptake sites were investigated by endoscopy or surgery. Results. Height endoscopy results were negative (17%). We found 25 adenomatous polyps (53.2%), 10 neoplasms (21.3%) and 4 inflammatory lesions (8.5%). 18-FDG uptake values were not statistically different between the 4 groups. Conclusion. Eighty-three percent of unexpected intestinal foci of hypermetabolism are either inflammatory, malignant or premalignant lesions. These results justify systematic investigation of these lesions.
authors.affiliation: Service de médecine nucléaire, fédération de médecine nucléaire CAL, centre Antoine-Lacassagne, CHU de Nice, 33, avenue de Valombrose, 06189 Nice cedex, France. laetg4@free.fr
authors.forename: Laetitia
authors.initials: L
authors.lastname: Tessonnier
authors.forename: Sebastien
authors.initials: S
authors.lastname: Gonfrier
authors.forename: Patricia
authors.initials: P
authors.lastname: Carrier
authors.forename: Laure
authors.initials: L
authors.lastname: Valerio
authors.forename: Jérôme
authors.initials: J
authors.lastname: Mouroux
authors.forename: Danielle
authors.initials: D
authors.lastname: Benisvy
authors.forename: Philippe
authors.initials: P
authors.lastname: Viau
authors.forename: Astrid
authors.initials: A
authors.lastname: Girma
authors.forename: Françoise
authors.initials: F
authors.lastname: Bussière
authors.forename: Jacques
authors.initials: J
authors.lastname: Darcourt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D006801:Humans; D033162:Incidental Findings; D007413:Intestinal Mucosa / Q000378:metabolism*; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D007417:Intestinal Polyps / Q000000981:diagnostic imaging / Q000378:metabolism; D007422:Intestines / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods; D011230:Precancerous Conditions / Q000000981:diagnostic imaging / Q000378:metabolism*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D012189:Retrospective Studies; D012811:Sigmoid Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18