Positron emission tomography features of canine necrotizing meningoencephalitis.
A Yorkshire terrier and a Chihuahua were referred for acute onset, generalized tonic-clonic seizures and were suspected to have meningoencephalitis based on magnetic resonance (MR) imaging findings. Brain lesions appeared hyperintense with T2-weighted imaging and hypointense with T1-weighted imaging, and were characteristic of necrotizing meningoencephalitis. Both dogs were diagnosed with necrotizing meningoencephalitis based on pathologic findings. Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) was performed on both animals before euthanasia with the permission of the owner. In FDG-PET images, these lesions seen in MR images were characterized by multifocal or diffuse hypometabolism. Our FDG-PET results provided evidence of glucose hypometabolism in areas of necrosis and cavitation associated with necrotizing meningoencephalitis. FDG-PET has the potential to provide valuable diagnostic information in dogs with suspected necrotizing encephalitis.
Eom
Ki-Dong
KD
Department of Veterinary Imaging, College of Veterinary Medicine, Konkuk University, Seoul, Korea.
Lim
Chae-Young
CY
Gu
Su-Hyun
SH
Kang
Byeong-Teck
BT
Kim
Young-Bo
YB
Jang
Dong-Pyo
DP
Woo
Eung-Je
EJ
Kim
Daeyoung
D
Cho
Zang-Hee
ZH
Park
Hee-Myung
HM
D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D004285:Dogs; D004830:Epilepsy, Tonic-Clonic / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D008590:Meningoencephalitis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D049268:Positron-Emission Tomography / Q000379:methods / Q000662:veterinary*