title: [Staphylococcic necrotizing pneumopathy due to Panton-Valentine leukocidin toxin with good outcome].
abstract: Panton-Valentine leukocidin (PLV) is a toxin produced by Staphylococcus aureus. Previously described as responsible for furunculoses and cutaneous abscesses, it was recently found to cause necrotizing pneumonia, generally lethal. We describe a case of necrotizing pneumonia caused by S. aureus containing PLV with an atypical form (bubble form), which had a good outcome despite several risk factors for death: hemoptysis, leukopenia, erythrodermia.
authors.affiliation: SAMU de Cayenne, centre hospitalier de Cayenne, Cayenne, Guyane française. miquel.barcelo@wanadoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Barcelo
authors.forename: E
authors.initials: E
authors.lastname: Chauvet
authors.forename: R
authors.initials: R
authors.lastname: Boukhari
authors.forename: B
authors.initials: B
authors.lastname: Mbieleu
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001427:Bacterial Toxins; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005098:Exotoxins; D005500:Follow-Up Studies; D006801:Humans; D007956:Leukocidins; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D010068:Oxacillin / Q000008:administration & dosage / Q000627:therapeutic use; D011023:Pneumonia, Staphylococcal / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology; D025762:Pristinamycin / Q000008:administration & dosage / Q000627:therapeutic use; D013902:Radiography, Thoracic; D012307:Risk Factors; D013211:Staphylococcus aureus / Q000378:metabolism; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D025762:Pristinamycin; D002981:Clindamycin; D010068:Oxacillin; D008775:Methylprednisolone