title: Coronary endarterectomy in the left anterior descending artery.
abstract: BACKGROUND
  The diffusely diseased coronary artery is a challenge for cardiac surgeons. Although coronary endarterectomy is an option for surgical reconstruction of a diffusely diseased vessel, it has not been widely used. We assessed the early clinical and angiographic outcomes of patients undergoing coronary endarterectomy of the left anterior descending artery (LAD) with a patch plasty method using the left internal thoracic artery (LITA). Furthermore, we assessed the coronary artery velocity flow reserve (CFVR) of the endarterectomized LAD.
  
  
  METHODS
  We retrospectively reviewed the records of 148 patients undergoing LAD endarterectomy using the in situ LITA. Direct endarterectomy was performed with a long segmental incision of the LAD that was reconstructed with the longitudinally incised LITA. The mean age at surgery was 65.1±8.6 years. Previous myocardial infarction was observed in 58.1% of the patients. The mean Canadian Cardiovascular Society score was 2.4±0.9. Postoperative angiography was performed in 134 patients (91.2%) during the same hospitalization (mean, 11.2±9.0 postoperative days). CFVR in the LAD was measured early after the operation by transthoracic echocardiography.
  
  
  RESULTS
  The mean number of distal anastomoses per patient was 4.2±1.3. The mean length of reconstructed LAD with endarterectomy was 5.8±1.5 cm. The operative mortality was 2.7%. Low cardiac output occurred in 6.1% of the patients. Perioperative myocardial infarction was observed in 12.2% of the patients, but severe ventricular arrhythmia was not encountered. The patency rate of the LITA to LAD was 94.0% by early angiographic examination. The mean CFVR in the endarterectomized LAD was 2.41±0.66.
  
  
  CONCLUSIONS
  Coronary endarterectomy of the LAD with a patch plasty using the LITA is associated with acceptable mortality, morbidity, and angiographic patency. CVFR measured by transthoracic echocardiography showed a favorable functional status in the endarterectomized LAD. Endarterectomy is considered to be one of the available surgical methods for patients with a diffusely diseased LAD.
authors.affiliation: Department of Cardiovascular Surgery, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu-shi, Tokyo 183-0003, Japan. takanashi-s@gem.hi-ho.ne.jp
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Takanashi
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Fukui
authors.forename: Yuji
authors.initials: Y
authors.lastname: Miyamoto
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000503:physiopathology / Q000601:surgery*; D004452:Echocardiography; D004691:Endarterectomy / Q000379:methods* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000601:surgery; D011183:Postoperative Complications; D012189:Retrospective Studies