title: [Establishment and rudimentary application of the method of recording auditory brainstem responses electrically stimulated via round-window niche in cochlear implants].
abstract: OBJECTIVE
  To establish the method of recording auditory brainstem responses electrically stimulated via round-window niche in cochlear implants.
  
  
  METHODS
  Self-made platinum iridium alloy as a spherical electrode stimulation electrode, modified cochlear implants connected to in vitro speech processor as a electro-stimulator and evoke potential instrument for Bio-logic Navigator Pro, 17 cochlear implant patients with various ages and of different causes, including auditory neuropathy (2 cases), ossified cochlea (1 case), inner ear malformation (5 cases), leukodystrophy (1 case), unknown and reason (8 cases) were investigated during cochlear implant surgery. Before cochlear implantation, stimulation electrode was placed in the round-window niche while charge balanced biphasic constant current was used as electrical stimulation via round window niche, and then electrically evoked auditory brainstem response was recorded.
  
  
  RESULTS
  Electrically evoked auditory brainstem response waveforms were clearly recorded in all 17 cases. The latencies of III and V waves were (2.12 +/- 0.18) ms and (4.18 +/- 0.19) ms respectively, with threshold as (220.0 +/- 16.04) CL. The waveforms of the 2 patients with auditory neuropathy, 5 patients with inner ear malformation, 1 patient with ossified cochlea and 1 patient with leukodystrophy were well differentiated.
  
  
  CONCLUSIONS
  Monitoring electrically evoked auditory brainstem response was an objective nerve electrophysiological testing method that accurately reflects function completeness of auditory pathway. It had important value for helping making the judgment whether patients could acquire auditory response after cochlear implantation. This method was safe and gave high emission of auditory response, therefore should be spread widely.
authors.affiliation: Cochlear Implant Centre, Peking Union Medical College Hospital, Beijing 100730, China.
authors.forename: Jing-Ning
authors.initials: JN
authors.lastname: Cheng
authors.forename: Ke-Li
authors.initials: KL
authors.lastname: Cao
authors.forename: Chao-Gang
authors.initials: CG
authors.lastname: Wei
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Yang
authors.forename: Lan
authors.initials: L
authors.lastname: Luan
authors.forename: Huan
authors.initials: H
authors.lastname: Li
authors.forename: Yuan
authors.initials: Y
authors.lastname: Li
authors.forename: Qiu-Hang
authors.initials: QH
authors.lastname: Zhang
mesh_terms: D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003054:Cochlear Implants; D004558:Electric Stimulation; D004566:Electrodes; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012405:Round Window, Ear / Q000502:physiology*; D000160:Vestibulocochlear Nerve Diseases / Q000503:physiopathology*