Pagetoid reticulosis (Woringer-Kolopp disease).
Pagetoid reticulosis (Woringer-Kolopp disease) is a rare subtype of cutaneous CD8-positive T-cell lymphoma. A 41-year-old man presented with a 7-year history with a slowly progressive erythematous plaque on his right buttocks. With the working diagnosis of psoriasis, he was treated with topical corticosteroids which produced no improvement. Histological examination showed an epidermotropic T-cell lymphoma with predominance of CD8- vs.CD4-positive lymphocytes. Based on the clinical picture and the histological findings, we diagnosed pagetoid reticulosis. Excision of the plaque and cream PUVA photo-chemotherapy produced long-term remission.
Lichte
Verena
V
Department of Dermatology, Clinic of the University of Tübingen, Germany.
Ghoreschi
Kamran
K
Metzler
Gisela
G
Möhrle
Mathias
M
Geyer
Annette
A
Röcken
Martin
M
Schaller
Martin
M
D000328:Adult; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000473:pathology* / Q000628:therapy*; D011701:PUVA Therapy