title: [Epidemiology of prostate cancer from three centers and analysis of the first-line hormonal therapy for the advanced disease].
abstract: OBJECTIVE
  To analyze the epidemiology information of prostate cancer from three centers of Beijing, Shanghai, Guangzhou, and to reflect the current situation of prostate cancer in China, and to analyze the information of 272 patients with advanced prostate cancer who received hormonal therapy to find the prognostic factors of hormone therapy.
  
  
  METHODS
  Collect the information of 525 patients with prostate cancer from three centers. Two hundred and seventy-two cases of advanced prostate cancer with full information were selected from the 525 cases to analyze the prognostic factors of hormone therapy.
  
  
  RESULTS
  Three hundred and fifty-seven cases (68.0%) had advanced disease at diagnosis and 80.2% patients received hormone therapy as the main therapy. Prognostic analysis indicated that Gleason score, bone metastasis and prostate specific antigen nadir were independent prognostic factors of progression-free survival time.
  
  
  CONCLUSIONS
  In this report, most patients are advanced prostate cancer at diagnose, and hormonal therapy is the main therapy. Gleason score, bone metastasis, prostate specific antigen nadir are independent prognostic factors of advanced prostate cancer after hormone therapy.
authors.affiliation: Department of Oncology, Shanghai Medical College, Shanghai 200032, China.
authors.forename: Chun-guang
authors.initials: CG
authors.lastname: Ma
authors.forename: Ding-wei
authors.initials: DW
authors.lastname: Ye
authors.forename: Chang-ling
authors.initials: CL
authors.lastname: Li
authors.forename: Fang-jian
authors.initials: FJ
authors.lastname: Zhou
authors.forename: Xu-dong
authors.initials: XD
authors.lastname: Yao
authors.forename: Shi-lin
authors.initials: SL
authors.lastname: Zhang
authors.forename: Bo
authors.initials: B
authors.lastname: Dai
authors.forename: Hai-liang
authors.initials: HL
authors.lastname: Zhang
authors.forename: Yao
authors.initials: Y
authors.lastname: Zhu
authors.forename: Yi-jun
authors.initials: YJ
authors.lastname: Shen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000726:Androgen Antagonists / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D002681:China; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D016019:Survival Analysis
chemical_list: D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal