title: Cells of rhabdomyosarcoma PA-23 tumor clones with high and low metastatic potential differ by activity of lysosomal sialidase.
abstract: We studied activity of lysosomal sialidase in cells of rhabdomyosarcoma PA-23 tumor clones with high and low metastatic potential. Low activity of lysosomal sialidase was found in clones characterized by high metastatic potential.
authors.affiliation: Department of Cellular and Molecular Pathology, A. M. Nikiforov Russian Center of Emergency and Radiation Medicine, Ministry of Emergency Situations.
authors.forename: S N
authors.initials: SN
authors.lastname: Proshin
authors.forename: E V
authors.initials: EV
authors.lastname: Kaminskaya
authors.forename: A A
authors.initials: AA
authors.lastname: Lebedev
authors.forename: P D
authors.initials: PD
authors.lastname: Shabanov
mesh_terms: D000818:Animals; D008247:Lysosomes / Q000201:enzymology; D009362:Neoplasm Metastasis / Q000473:pathology* / Q000503:physiopathology; D009439:Neuraminidase / Q000378:metabolism*; D051381:Rats; D012208:Rhabdomyosarcoma / Q000201:enzymology* / Q000473:pathology*
chemical_list: D009439:Neuraminidase