A previously healthy 11-year-old girl with behavioural disturbances, desquamation of the skin and loss of teeth.
An 11-year-old girl was admitted with backpain, weight loss, fatigue and behavioural disturbances, starting seven weeks before admission. Physical examination showed acrodynia, tremor, cachexia, hypertension and extensive gingival ulceration. Routine laboratory tests were normal, except for a CRP of 98 mg/l. Screening tests for recreational drugs as well as antibody assays for HIV, hepatitis B and borrelia burgdorferia were negative. Chest X-ray, brain CAT and MRI scan were all normal. Lumbar puncture didn't show any abnormalities. Eventually a 24-hour urine test confirmed the diagnosis that was suspected by further questioning.
van der Linde
A A A
AA
Department of Paediatrics, Canisius Wilhelmina Hospital, P.O. Box 9015, 6500 GS, Nijmegen, The Netherlands.
Lewiszong-Rutjens
C A W
CA
Verrips
A
A
Gerrits
G P J M
GP
D002614:Chelating Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000139:chemically induced* / Q000175:diagnosis; D008628:Mercury / Q000097:blood; D008630:Mercury Poisoning / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D012871:Skin Diseases / Q000139:chemically induced* / Q000175:diagnosis; D016388:Tooth Loss / Q000139:chemically induced* / Q000175:diagnosis; D014494:Unithiol / Q000627:therapeutic use
D002614:Chelating Agents; D014494:Unithiol; D008628:Mercury