Caudal midazolam does not affect sevoflurane requirements and recovery in pediatric day-case hernioplasty.
BACKGROUND
This prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.


METHODS
Sixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 microg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50.


RESULTS
Concentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group.


CONCLUSIONS
Caudal midazolam (50 microg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.
Hong
J-Y
JY
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seodaemun-Gu, Seoul, Korea. jenyhongg@hanmail.net
Lee
I H
IH
Shin
S K
SK
Park
E Y
EY
Ban
S Y
SY
Cho
J E
JE
Kil
H K
HK
D000556:Ambulatory Surgical Procedures; D000577:Amides / Q000008:administration & dosage; D000762:Anesthesia Recovery Period; D000763:Anesthesia, Caudal / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage; D002675:Child, Preschool; D004311:Double-Blind Method; D059685:Herniorrhaphy; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D008874:Midazolam / Q000008:administration & dosage*; D010147:Pain Measurement; D011446:Prospective Studies; D000077212:Ropivacaine; D000077149:Sevoflurane; D013990:Tidal Volume; D016896:Treatment Outcome
D000577:Amides; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D008738:Methyl Ethers; D000077149:Sevoflurane; D000077212:Ropivacaine; D008874:Midazolam