title: Why is SIMS underused in chemical and biological analysis? Challenges and opportunities.
abstract: Improvements have led to many developments in SIMS, including better 2D MS imaging, the ability to perform molecular depth profiling, and the development of 3D MS imaging. (To listen to a podcast about this feature, please go to the Analytical Chemistry website at pubs.acs.org/ac.).
authors.affiliation: Washington University, St. Louis, USA. walker@wuchem.wustl.edu
authors.forename: Amy V
authors.initials: AV
authors.lastname: Walker
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional; D056656:Lab-On-A-Chip Devices; D046208:Microchip Analytical Procedures / Q000379:methods; D004364:Pharmaceutical Preparations / Q000032:analysis; D051381:Rats; D018629:Spectrometry, Mass, Secondary Ion / Q000295:instrumentation / Q000379:methods* / Q000639:trends*
chemical_list: D004364:Pharmaceutical Preparations