67Gallium citrate scintigraphy to assess metastatic spread in a dog with an oral melanoma.
Gallium scintigraphy was used to evaluate therapeutic response in a 10-year-old, male, Dutch sheepdog, suffering from an oral melanoma. Treatment was performed with a combination of carboplatin and hypofractionated radiation. Nineteen weeks after radiation therapy, the left submandibular lymph node was surgically removed because of metastatic disease. Thirty weeks after radiation therapy, 67Gallium scintigraphy was performed to assess for residual disease and metastasis. Increased uptake in the right submandibular lymph node area was noted and identified as a melanoma metastasis on cytology. Surgical excision was performed. Twenty-one weeks later, the dog was euthanased because of advanced pulmonary metastases. This report of a case of oral melanoma illustrates the advantages of 67Gallium scintigraphy in monitoring for the presence of metastatic disease and effectiveness of therapy.
Liuti
T
T
De Ottenhorst, Clinic for Companion Animal Medicine and Veterinary Oncology Referral Center, van Diemenstraat 83, 4535 AR Terneuzen, The Netherlands.
de Vos
J
J
Bosman
T
T
van de Wiele
C
C
Grinwis
G C M
GC
van Bree
H
H
Peremans
K
K
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D002951:Citrates; D003131:Combined Modality Therapy; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D004285:Dogs; D037901:Euthanasia, Animal; D005708:Gallium; D005710:Gallium Radioisotopes; D008197:Lymph Node Excision / Q000662:veterinary; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging / Q000628:therapy / Q000662:veterinary*; D009062:Mouth Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy / Q000662:veterinary*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013365:Submandibular Gland Neoplasms / Q000556:secondary / Q000601:surgery / Q000662:veterinary
D000970:Antineoplastic Agents; D002951:Citrates; D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D016190:Carboplatin; D005708:Gallium; C103850:gallium citrate