[Modification by various neuromediators and regulatory peptides of the impulsation activity of neurons in the medial vestibular nucleus].
Cats were immobilized with myorelaxation agents to apply the microelectrode technique and microlonophoresis of physiologically active substances. As a result it was shown that various classic neuromediators (GABA, taurine and others) and regulatory peptides (vasoactive intestinal peptide (VIP), somatostatine (SS) and others) have effect on the majority (62 to 100%) of neurons in the medial vestibular nucleus. In the presence of L-glutamate VIP and SS CC retained essentially their inhibitory effect on the neurons impulse activity. Both VIP and SS were found to amplify the inhibitory action of GABA and glycine. To sum up, the substances under study can function as neuromediators and/or neuromodulators in the medial vestibular nucleus.
Iasnetsov
V V
VV
Pravdivtsev
V A
VA
Motin
V G
VG
Karsanova
S K
SK
Ivanov
Iu V
IuV
D000818:Animals; D002415:Cats; D008297:Male; D008564:Membrane Potentials / Q000502:physiology; D008839:Microelectrodes; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D014726:Vestibular Nuclei / Q000502:physiology*
D009479:Neuropeptides