title: Metabolic syndrome resolution in children and adolescents after 10 weeks of weight loss.
abstract: Without aggressive intervention, childhood obesity and the metabolic syndrome may result in lifelong physical consequences. Interventions that emphasize healthy eating and regular exercise are crucial to stop this epidemic and its ramifications. This paper discusses the incidence of the metabolic syndrome and cardiovascular risk factors before and after a weight loss program. A retrospective review was conducted in 135 children and adolescents (aged 6 to 19) who completed a 10-week medically supervised weight loss program. Outcome measures included mean change in each component of the metabolic syndrome, total cholesterol, low-density lipoprotein cholesterol, and hemoglobin A(1c). After 10 weeks of weight loss, a mean (SD) weight loss of 9.24 (19.5) kg was attained. Resolution of the metabolic syndrome was seen in 75.5% of children and adolescents. Weight loss can reverse metabolic syndrome and decrease cardiovascular risk in as little as 10 weeks.
authors.affiliation: Lindora Inc., Costa Mesa, CA 92626, USA. annmarie.coppen@lindora.com
authors.forename: Ann Marie
authors.initials: AM
authors.lastname: Coppen
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Risser
authors.forename: Peter D
authors.initials: PD
authors.lastname: Vash
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002140:California / Q000453:epidemiology; D002648:Child; D050528:Diet, Carbohydrate-Restricted / Q000379:methods*; D018752:Diet, Fat-Restricted / Q000379:methods*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss; D055815:Young Adult