Microwave-assisted Wolff rearrangement of cyclic 2-diazo-1,3-diketones: an eco-compatible route to alpha-carbonylated cycloalkanones.
The microwave-assisted Wolff rearrangement of cyclic 2-diazo-1,3-diketones performed in the presence of a stoichiometric amount of alcohol, amine, or thiol is an efficient, user, and environmentally friendly synthetic protocol for the synthesis of alpha-carbonylated cycloalkanones. This approach proves superior to existing protocols in scope and eco-compatibility.
Presset
Marc
M
Universite Paul Cezanne, Institut des Sciences Moleculaires de Marseille, ISM2-UMR CNRS 6263, Centre Saint Jerome, Service 531, 13397 Marseille Cedex 20, France.
Coquerel
Yoann
Y
Rodriguez
Jean
J
D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry* / Q000528:radiation effects; D008872:Microwaves; D015394:Molecular Structure; D013237:Stereoisomerism
D007659:Ketones