Two-directional olefinic-ester ring-closing metathesis using reduced Ti alkylidenes. A rapid entry into polycyclic ether skeletons.
The use of a reduced titanium ethylidene reagent in an efficient two-directional approach to polycyclic ether skeletons is described.
Zhang
Yuan
Y
Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112, USA.
Rainier
Jon D
JD
D000475:Alkenes / Q000737:chemistry*; D003500:Cyclization; D004952:Esters / Q000737:chemistry*; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014025:Titanium / Q000737:chemistry*
D000475:Alkenes; D004952:Esters; D004987:Ethers; D009942:Organometallic Compounds; D011083:Polycyclic Compounds; D014025:Titanium