Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter.
OBJECTIVE
The aim of this study was to determine if warming patients prior to and during (18)F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).


METHODS
A group of 40 children underwent (18)F-FDG PET after being kept in the injection room at a constant temperature of 24 degrees C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21 degrees C.


RESULTS
Uptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21 degrees C (p<0.002).


CONCLUSIONS
Maintaining room temperature at a constant 24 degrees C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.
Zukotynski
Katherine A
KA
Department of Radiology, Division of Nuclear Medicine/PET, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.
Fahey
Frederic H
FH
Laffin
Stephen
S
Davis
Royal
R
Treves
S Ted
ST
Grant
Frederick D
FD
Drubach
Laura A
LA
D002001:Adipose Tissue, Brown / Q000378:metabolism*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000494:pharmacology*; D012189:Retrospective Studies; D012621:Seasons; D013696:Temperature
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18