title: The effect of Behçet's disease on sexual function and psychiatric status of premenopausal women.
abstract: BACKGROUND
  Little is known about the relationship between Behçet's disease (BD) and female sexual dysfunction (FSD).
  
  
  OBJECTIVE
  The aims were to evaluate the prevalence of FSD in premenopausal BD patients and to compare hormonal and psychiatric conditions to healthy subjects.
  
  
  METHODS
  A total of 71 married women with BD and 63 healthy married women between 18 and 44 years old were enrolled into the study. After evaluating detailed history and physical examination, serum steroid hormone levels were measured. Presence of genital ulcerations in physical examination and any medical treatment were recorded in patients. All subjects were asked to complete the Female Sexual Function Index (FSFI) for sexual status and Beck Depression Inventory (BDI) for psychiatric assessment.
  
  
  METHODS
  FSFI and BDI scores and serum sex steroid hormone levels were measured in women with BD and healthy controls.
  
  
  RESULTS
  The mean BDI score of patients was significantly greater than that for controls (P = 0.001), and there was a statistically significant difference between BDI scores (Pearson chi2 = 19.109, P = 0.001). FSD was found in 34 patients with BD (47.9%) and in 11 controls (17.5%). A statistically significant difference was found between the two groups (Pearson chi2 = 13.855, P = 0.001). While the most common sexual problem in the patients with BD was diminished arousal (n = 49, 69.0%), diminished desire was found in 32 patients (45.1%) and lubrication problems in 36 patients (50.7%). There was a statistically significant negative correlation between BDI and FSFI score in BD patients. On the contrary, there was no relationship between FSFI and presence of genital ulcerations.
  
  
  CONCLUSIONS
  FSD is more common in BD patients than in healthy subjects. We conclude that depressive mood according to the BDI scale correlates with the sexual status of BD patients, and this may be because of the depressive effect of BD as a chronic disease.
authors.affiliation: Department of Dermatology, University of Kirikkale, School of Medicine, Kirikkale, Turkey.
authors.forename: Mukadder
authors.initials: M
authors.lastname: Koçak
authors.forename: M Murad
authors.initials: MM
authors.lastname: Başar
authors.forename: Güler
authors.initials: G
authors.lastname: Vahapoğlu
authors.forename: H Cağatay
authors.initials: HC
authors.lastname: Mert
authors.forename: Sule
authors.initials: S
authors.lastname: Güngör
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D017697:Premenopause; D015995:Prevalence; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D020018:Sexual Dysfunctions, Psychological / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D011795:Surveys and Questionnaires