title: Synthesis, chemical speciation and SOD mimic assays of tricarballylic acid-copper(II) and imidazole-tricarballylic acid-copper(II) complexes.
abstract: The coordination behavior of copper(II) with tricarballylic acid (H(3)TCA) and imidazole (Imz) is described. Speciation in aqueous solution has been determined at 25 degrees C and 0.15M NaCl ionic strength by potentiometric measurements and EPR characterization of the species. Two new compounds CuTCAH.3H(2)O and CuTCAHImz.2H(2)O were obtained and characterized by elemental analysis diffuse reflectance, FTIR (Fourier transform infrared spectroscopy), EPR and thermal behavior. Their in vitro superoxide dismutase-mimetic activities have been tested.
authors.affiliation: CEQUINOR (Centro de Química Inorgánica), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, 47 y 115 (1900) La Plata, Argentina.
authors.forename: Luciana
authors.initials: L
authors.lastname: Naso
authors.forename: Ana C
authors.initials: AC
authors.lastname: González Baró
authors.forename: Luis
authors.initials: L
authors.lastname: Lezama
authors.forename: Teófilo
authors.initials: T
authors.lastname: Rojo
authors.forename: Patricia A M
authors.initials: PA
authors.lastname: Williams
authors.forename: Evelina G
authors.initials: EG
authors.lastname: Ferrer
mesh_terms: D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013482:Superoxide Dismutase / Q000138:chemical synthesis / Q000737:chemistry*; D014233:Tricarboxylic Acids / Q000737:chemistry*
chemical_list: C538913:(imidazole)(tricarballylic acid)copper(II); C538912:(tricarballylic acid)copper(II); D007093:Imidazoles; D009942:Organometallic Compounds; D014233:Tricarboxylic Acids; D003300:Copper; D013482:Superoxide Dismutase; C028021:tricarballylic acid