Case report: failure of subcutaneous ivermectin in treating Strongyloides hyperinfection.
A man with Escherichia coli meningitis and bacteremia, while on dexamethasone, developed Strongyloides hyperinfection syndrome and died despite salvage therapy with subcutaneous ivermectin. We report the first documented total and free levels of subcutaneous ivermectin used for therapy.
Leung
Victor
V
Department of Internal Medicine, University of British Columbia, Vancouver General Hospital, Vancouver, British Columbia, Canada. victor.leung@mail.mcgill.ca
Al-Rawahi
Ghada N
GN
Grant
Jennifer
J
Fleckenstein
Lawrence
L
Bowie
William
W
D000368:Aged; D000818:Animals; D000977:Antiparasitic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007279:Injections, Subcutaneous; D007559:Ivermectin / Q000008:administration & dosage* / Q000627:therapeutic use*; D008297:Male; D017171:Strongyloides stercoralis; D013322:Strongyloidiasis / Q000150:complications / Q000188:drug therapy* / Q000469:parasitology
D000977:Antiparasitic Agents; D007559:Ivermectin