title: Perfusion imaging of the pancreas using an arterial spin labeling technique.
abstract: OBJECTIVE
  To investigate the feasibility of perfusion imaging of the pancreas using an arterial spin labeling (ASL) technique.
  
  
  METHODS
  An adapted flow-sensitive alternating inversion recovery (FAIR)-TrueFISP ASL technique was implemented on a 1.5 T scanner. Anatomical and perfusion imaging in three different parts of the pancreas were performed in 10 healthy volunteers. Quantitative perfusion values were calculated using the extended Bloch equations.
  
  
  RESULTS
  Perfusion images of all subjects showed diagnostic image quality in the pancreatic tail and the head. Assessment of pancreatic tissue perfusion was possible in all organ parts. Mean perfusion values were 271 +/- 79 mL/100g/min in the head, 351 +/- 112 mL/100g/min in the body, and 243 +/- 55 mL/100g/min in the tail of the pancreas. Total examination time for perfusion imaging of the entire organ was 15.4 minutes.
  
  
  CONCLUSIONS
  FAIR-TrueFISP permits analysis of pancreatic tissue perfusion with good image quality in a clinically applicable measuring time. Assessment of perfusion disorders may be useful in the diagnosis of inflammatory pancreatic pathologies, endocrine and exocrine pancreatic disorders, and in monitoring of pancreatic transplants.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany. christina.schraml@med.uni-tuebingen.de
authors.forename: Christina
authors.initials: C
authors.lastname: Schraml
authors.forename: Nina F
authors.initials: NF
authors.lastname: Schwenzer
authors.forename: Petros
authors.initials: P
authors.lastname: Martirosian
authors.forename: Claus D
authors.initials: CD
authors.lastname: Claussen
authors.forename: Fritz
authors.initials: F
authors.lastname: Schick
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010179:Pancreas / Q000098:blood supply*; D013113:Spin Labels
chemical_list: D013113:Spin Labels