Temporary placement of a fully covered self-expandable metal stent in the pancreatic duct for management of symptomatic refractory chronic pancreatitis: preliminary data (with videos).
BACKGROUND
Pancreatic duct (PD) stenting is beneficial for the treatment of pain in patients with PD strictures associated with chronic pancreatitis. Placement of metal stents has been reported but failed secondary to hyperplasia or migration.


OBJECTIVE
To investigate the outcome of patients with symptomatic and refractory PD strictures who had temporary placement of a covered self-expandable metal stent (CSEMS).


METHODS
Patients with refractory PD strictures were offered temporary CSEMS placement. Pain scores were evaluated before and after CSEMS placement.


METHODS
A tertiary-care center.


METHODS
Six patients (4 men, mean age +/- SD 55 +/- 8 years) received a CSEMS, and 5 patients had removal of a CSEMS after a mean time of 92 days.


METHODS
Placement of CSEMS (8-mm or 10-mm diameter VIABIL) in the PD, with removal after 3 months.


METHODS
The pain score before and after stent placement and the sustained response after removal. Morbidity associated with stent placement and removal was also noted.


RESULTS
Pain scores after CSEMS placement significantly improved (P = .024), from 6.4 to 1.6. Of the 5 patients who underwent CSEMS removal, 3 developed recurrent symptomatic pancreatic stricture, of whom 2 required repeat stenting with a larger-diameter CSEMS (10 mm) and 2 remained pain free. The CSEMS was not removed in 1 patient because pancreatic malignancy was diagnosed. There were no complications during placement or removal of CSEMSs.


CONCLUSIONS
This was a pilot study.


CONCLUSIONS
Temporary placement of CSEMSs in patients with symptomatic refractory PD stricture offers transient relief of pain. Further investigation is needed to determine the optimal diameter and duration of placement.
Sauer
Bryan
B
Digestive Health Center, University of Virginia Health System, Charlottesville, Virginia 22908-0708, USA.
Talreja
Jayant
J
Ellen
Kristi
K
Ku
Jennifer
J
Shami
Vanessa M
VM
Kahaleh
Michel
M
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts; D050500:Pancreatitis, Chronic / Q000601:surgery*; D011474:Prosthesis Design; D015607:Stents; D013997:Time Factors