NO-producing activity of macrophages infected with tick-borne encephalitis virus.
Stimulation of NO-producing activity of macrophages infected with tick-borne encephalitis virus was demonstrated. Activity of NADPH-diaphorase, inducible NO synthase, and cytochrome oxidase, a heme-containing mitochondrial enzyme reflecting NO production by the nitrite reductase pathway was observed against the background of production of NO metabolites by cells.
Plekhova
N G
NG
Institute of Epidemiology and Microbiology, Siberian Division of Russian Academy of Medical Sciences, Vladivostok. pl_nat@hotmail.com
Somova
L M
LM
Zavorueva
D V
DV
Krylova
N V
NV
Leonova
G N
GN
D000818:Animals; D002478:Cells, Cultured; D003576:Electron Transport Complex IV / Q000378:metabolism; D004669:Encephalitis Viruses, Tick-Borne; D008264:Macrophages / Q000378:metabolism* / Q000821:virology*; D051379:Mice; D009252:NADPH Dehydrogenase / Q000378:metabolism; D009569:Nitric Oxide / Q000096:biosynthesis*; D052247:Nitric Oxide Synthase Type II / Q000378:metabolism
D009569:Nitric Oxide; D052247:Nitric Oxide Synthase Type II; C496317:Nos2 protein, mouse; D009252:NADPH Dehydrogenase; D003576:Electron Transport Complex IV