Comparative evaluation of Trichosporon asahii susceptibility using ASTY colorimetric microdilution and CLSI M27-A2 broth microdilution reference methods.
The in vitro activity ofAMPH-B, 5-FC, FLCZ, MCZ, ITCZ, and VRCZ against 50 isolates of T. asahii was determined using CLSI M27-A2 microdilution and ASTY colorimetric methods. Observed agreement ranged from 96 to 100% according to the drug. Overall, the agreement between two methods was 97.7%. The ASTY colorimetric method was thus determined to be comparable to the CLSI reference method when testing the susceptibility of T. asahii to a variety of antifungal agents.
Kalkanci
Ayse
A
Gazi University Faculty of Medicine, Department of Microbiology, Besevler, Ankara, 06500, Turkey.
Mekha
Nanthawan
N
Poonwan
Natteewan
N
Makimura
Koichi
K
Sugita
Takashi
T
D000935:Antifungal Agents / Q000494:pharmacology; D003124:Colorimetry / Q000379:methods* / Q000592:standards; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods* / Q000592:standards; D014250:Trichosporon / Q000187:drug effects*
D000935:Antifungal Agents