title: Positron emission tomography features of canine necrotizing meningoencephalitis.
abstract: A Yorkshire terrier and a Chihuahua were referred for acute onset, generalized tonic-clonic seizures and were suspected to have meningoencephalitis based on magnetic resonance (MR) imaging findings. Brain lesions appeared hyperintense with T2-weighted imaging and hypointense with T1-weighted imaging, and were characteristic of necrotizing meningoencephalitis. Both dogs were diagnosed with necrotizing meningoencephalitis based on pathologic findings. Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) was performed on both animals before euthanasia with the permission of the owner. In FDG-PET images, these lesions seen in MR images were characterized by multifocal or diffuse hypometabolism. Our FDG-PET results provided evidence of glucose hypometabolism in areas of necrosis and cavitation associated with necrotizing meningoencephalitis. FDG-PET has the potential to provide valuable diagnostic information in dogs with suspected necrotizing encephalitis.
authors.affiliation: Department of Veterinary Imaging, College of Veterinary Medicine, Konkuk University, Seoul, Korea.
authors.forename: Ki-Dong
authors.initials: KD
authors.lastname: Eom
authors.forename: Chae-Young
authors.initials: CY
authors.lastname: Lim
authors.forename: Su-Hyun
authors.initials: SH
authors.lastname: Gu
authors.forename: Byeong-Teck
authors.initials: BT
authors.lastname: Kang
authors.forename: Young-Bo
authors.initials: YB
authors.lastname: Kim
authors.forename: Dong-Pyo
authors.initials: DP
authors.lastname: Jang
authors.forename: Eung-Je
authors.initials: EJ
authors.lastname: Woo
authors.forename: Daeyoung
authors.initials: D
authors.lastname: Kim
authors.forename: Zang-Hee
authors.initials: ZH
authors.lastname: Cho
authors.forename: Hee-Myung
authors.initials: HM
authors.lastname: Park
mesh_terms: D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D004285:Dogs; D004830:Epilepsy, Tonic-Clonic / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D008590:Meningoencephalitis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D049268:Positron-Emission Tomography / Q000379:methods / Q000662:veterinary*