title: Coronary artery bypass grafting in patients on maintenance dialysis: is peritoneal dialysis a risk factor of operative mortality?
abstract: BACKGROUND
  Increasing numbers of patients on dialysis are undergoing coronary artery bypass grafting (CABG). We undertook this retrospective study to identify risk factors of operative mortality in dialysis patients who underwent CABG.
  
  
  METHODS
  We performed retrospective analysis of 105 patients who were on dialysis for at least two months before surgery and who underwent CABG in Toronto General Hospital from 1997 to 2006. Using prospectively collected data from the Division of Cardiovascular Surgery Database of Toronto General Hospital, we collected data on comorbidities, procedures, modality change during hospitalization, and operative outcomes. Logistic regression was used to assess risk factors of operative mortality.
  
  
  RESULTS
  One hundred and five maintenance dialysis patients (40 PD and 65 HD) who met the inclusion criteria were studied. Overall in-hospital mortality was 7.6%. Atrial fibrillation and pneumonia occurred in 16.2 and 9.5%, respectively, of all dialysis patients. Among PD patients, rates of post-operative dialysate leak and peritonitis were 10 and 12.5%, respectively. Among HD patients, 4.6% experienced post-operative AV access thrombosis. Logistic regression showed older age (>or=70 years) and peritoneal dialysis are independent risk factors of operative mortality.
  
  
  CONCLUSIONS
  In this retrospective study, older patients on PD had higher operative mortality than HD patients. These findings suggest extra care should be taken when CABG is considered for PD patients over 70 years old. In this study we could not identify the reason(s) for the high mortality of elderly peritoneal dialysis patients undergoing CABG.
authors.affiliation: Department of Medicine, Division of Nephrology, University Health Network and University of Toronto, Toronto, ON, Canada. zhongyihui@hotmail.com
authors.forename: Hui
authors.initials: H
authors.lastname: Zhong
authors.forename: Tirone
authors.initials: T
authors.lastname: David
authors.forename: Ai Hua
authors.initials: AH
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Fang
authors.forename: Mufazzal
authors.initials: M
authors.lastname: Ahmad
authors.forename: Joanne M
authors.initials: JM
authors.lastname: Bargman
authors.forename: Dimitrios G
authors.initials: DG
authors.lastname: Oreopoulos
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D006435:Renal Dialysis; D012189:Retrospective Studies; D012307:Risk Factors