title: Transient 2:1 atrioventricular block following anaphylactic reaction to low-ionic strength computed tomography contrast agent.
abstract: The present report describes the case of an elderly woman who was admitted to the hospital with sepsis and subsequently developed a transient 2:1 atrioventricular block following administration of a low-ionic strength contrast agent for computed tomography. The block resolved after approximately 24 h and did not require a temporary pacemaker. The case identifies an unusual consequence following an anaphylactic reaction to a low-ionic strength computed tomography contrast agent and suggests the potential role of histamine release as a mechanism underlying this reaction.
authors.affiliation: Division of Cardiology, University of British Columbia, British Columbia. aneez60@hotmail.com
authors.forename: Aneez
authors.initials: A
authors.lastname: Mohamed
authors.forename: Jason
authors.initials: J
authors.lastname: Andrade
authors.forename: Michael
authors.initials: M
authors.lastname: Bayliss
authors.forename: Graham C
authors.initials: GC
authors.lastname: Wong
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D054537:Atrioventricular Block / Q000139:chemically induced* / Q000150:complications; D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology; D003287:Contrast Media / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis; D018570:Risk Assessment; D018805:Sepsis / Q000175:diagnosis; D012720:Severity of Illness Index; D013122:Spinal Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D003287:Contrast Media