[Advance of researches on thyroid tissues autotransplantation and embryonic stem cell transplantation in therapy of hypothyroidism].
Patients with irreversible hypothyroidism require lifelong levo-thyroxin ( L-T4) replacement therapy, which makes them feel discomfortable. With the development of the thyroid tissues autotransplantation and embryonic stem cell (ESC), this would be a more physiological approach to the treatment of irreversible hypothyroidism. The animal experiments and human clinical trials on thyroid tissues autotransplantation have shown that the autograft can survive and function. The advanced researches have demonstrated that ESC can differentiate into thyroid follicular cells.
Ma
Quanfu
Q
Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu 610041, China.
Kuang
Anren
A
D000818:Animals; D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology / Q000637:transplantation*; D006801:Humans; D007037:Hypothyroidism / Q000601:surgery* / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods; D013961:Thyroid Gland / Q000166:cytology / Q000637:transplantation*; D014182:Transplantation, Autologous