In vitro study of the role of lenticular epithelial calcium channels and aquaporins in the development of cataract.
The role of calcium and water channels (aquaporins) in the pathogenesis of cataract was studied in vitro. Aquaporin blockade caused opacity of the lens sooner than changes in calcium ion concentration in culture medium.
Sumerkina
V A
VA
Chelyabinsk State Medical Academy. sva2501@rambler.ru
Popov
G K
GK
Voronova
L V
LV
D000818:Animals; D020346:Aquaporins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D002121:Calcium Channel Blockers / Q000378:metabolism; D015220:Calcium Channels / Q000378:metabolism*; D002386:Cataract / Q000378:metabolism / Q000473:pathology; D005260:Female; D007908:Lens, Crystalline / Q000378:metabolism / Q000473:pathology; D008297:Male; D051381:Rats; D046509:Tissue Culture Techniques
D020346:Aquaporins; D002121:Calcium Channel Blockers; D015220:Calcium Channels