Obesity across the lifespan among persons with spina bifida.
OBJECTIVE
Identify risk factors for obesity across the lifespan for individuals with spina bifida.


METHODS
Cross sectional chart review study of 203 patients aged 6-58 years. Obesity was based on body mass index. Rates were calculated for children aged 6-11 years; adolescents aged 12-19 years and adults aged > 20 years. Chi-square analyses were used to determine differences in obesity rates among subgroups. An ordered logistic regression model was developed for the three age groups to estimate the probability of a change in BMI classification from normal weight to overweight or overweight to obese, controlling for sex, functional motor level, shunt status and insurance status.


RESULTS
Obesity rates for children, adolescents and adults were 18, 8 and 37%, respectively. Obesity rates were higher among adults (chi2 = 27, p < 0.01) and for individuals who were publicly insured (chi2 = 7.2, p < 0.03). The ordered regression model for children demonstrated no independent association between sex, shunt status, functional motor level or insurance status and change in BMI category. For adolescents, lower functional motor level (i.e. sacral) increased the risk of becoming obese (Odds Ratio: 2.13; 95% CI: 1.12-4.06; p < 0.02). Among adults, female sex increased risk (OR = 2.28; 95% CI: 1.03-5.04; p < 0.04).


CONCLUSIONS
Obesity rates for children and adolescents with spina bifida are similar to the general population; however, obesity rates are higher among adults, particularly women. Risk factors are similar to those observed in the general population.
Dosa
Nienke P
NP
Center for Development, Behavior, and Genetics, SUNY Upstate Medical University, Syracuse, NY 13210, USA. dosan@upstate.edu
Foley
John T
JT
Eckrich
Michael
M
Woodall-Ruff
Denise
D
Liptak
Gregory S
GS
D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D016009:Chi-Square Distribution; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology*; D012307:Risk Factors; D012737:Sex Factors; D016135:Spinal Dysraphism / Q000453:epidemiology*