The prevention of dementia.
OBJECTIVE
Dementia is prevalent in older adults and the population is ageing. Many factors have been associated with dementia and anything that may aid the prevention of dementia is of importance.


METHODS
The literature in this area was evaluated and information relating to the various factors that may impact upon the prevention of dementia is presented below.


RESULTS
Factors that have been associated with a possible increased risk of developing dementia include high blood pressure, (at least in midlife), high body mass index, smoking and possibly diabetes although the evidence is mixed. There is currently no clear evidence with regard to cholesterol and metabolic syndrome although both may be implicated. Having education and maintaining a Mediterranean diet, including vegetable, fruit and fish intake, have been linked to a lower incidence of dementia as has low to moderate alcohol intake. Although care must be taken with the latter given the different characteristics of the studies reporting on alcohol and dementia.


CONCLUSIONS
It may be that risk and protective factors vary with age, however, in the absence of prophylactic treatment it seems likely that the maintenance of a healthy lifestyle may represent the best option with regard to the prevention of dementia.
Peters
Ruth
R
Imperial College Faculty of Medicine, Hammersmith Campus, London, UK. r.peters@imperial.ac.uk
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology / Q000523:psychology; D000428:Alcohol Drinking; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003704:Dementia / Q000517:prevention & control*; D004522:Educational Status; D015444:Exercise; D005260:Female; D015438:Health Behavior; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D000959:Antihypertensive Agents