Uncoupling of the patterns of chromatin association of different transcription elongation factors by a histone H3 mutant in Saccharomyces cerevisiae.
The transcription elongation complexes yFACT, Spt4/Spt5, and Spt6/Iws1 were previously shown to follow similar patterns of association across transcribed genes in Saccharomyces cerevisiae. Using a histone H3 mutant, we now provide evidence that the mechanism of association of yFACT across genes is separable from that adopted by Spt4/Spt5 and Spt6/Iws1.
Lloyd
Amanda
A
Biology Department, Hendrix College, 1600 Washington Avenue, Conway, AR 72032, USA.
Pratt
Katie
K
Siebrasse
Erica
E
Moran
Matthew D
MD
Duina
Andrea A
AA
D002843:Chromatin / Q000235:genetics / Q000378:metabolism*; D006657:Histones / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D011485:Protein Binding; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*; D035602:Transcriptional Elongation Factors / Q000235:genetics / Q000378:metabolism*
D002843:Chromatin; D006657:Histones; D029701:Saccharomyces cerevisiae Proteins; D035602:Transcriptional Elongation Factors