title: Selenite and selenate effects on mercury (Hg(2+)) uptake and distribution in tilapia, Oreochromis niloticus L., assessed by chronic bioassay.
abstract: Aquatic organisms are considered excellent biomarkers of mercury (Hg) occurrence in the environment. Selenium (Se) acts in antagonism to this metal, stimulating its elimination, and reducing its toxicity. In this paper, tilapia (Oreochromis niloticus) were chronically acclimated in sub-lethal Hg(2+), Hg(2+) + Se(4+) and Hg(2+) + Se(6+) concentrations. Distribution and bioaccumulation of both elements were evaluated in fish tissues. The kidney was the main target of the Hg and Se uptake, and the presence of Hg induced the Se hepatic elimination. The Hg bioaccumulation in the gill, spleen and heart were higher in the presence of Se(6+) than in the presence of Se(4+).
authors.affiliation: Analytical Chemistry Laboratory, Nuclear Energy Center for Agriculture, Avenida Centenário, Piracicaba, SP, Brazil. ggcarvalho@cena.usp.br
authors.forename: G G A
authors.initials: GG
authors.lastname: Carvalho
authors.forename: J G
authors.initials: JG
authors.lastname: de França
authors.forename: D C
authors.initials: DC
authors.lastname: Dias
authors.forename: J V
authors.initials: JV
authors.lastname: Lombardi
authors.forename: M J R
authors.initials: MJ
authors.lastname: de Paiva
authors.forename: S
authors.initials: S
authors.lastname: Carvalho
authors.forename: G A
authors.initials: GA
authors.lastname: Sarriés
authors.forename: J R
authors.initials: JR
authors.lastname: Ferreira
mesh_terms: D000818:Animals; D001681:Biological Assay; D008628:Mercury / Q000493:pharmacokinetics / Q000633:toxicity*; D064586:Selenic Acid; D018036:Selenium Compounds / Q000494:pharmacology*; D018038:Sodium Selenite / Q000494:pharmacology*; D017210:Tilapia / Q000378:metabolism*; D014018:Tissue Distribution; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics / Q000633:toxicity*
chemical_list: D018036:Selenium Compounds; D014874:Water Pollutants, Chemical; D008628:Mercury; D018038:Sodium Selenite; D064586:Selenic Acid