Prenatal diagnosis of annular pancreas: reliability of the double bubble sign with periduodenal hyperechogenic band.
OBJECTIVE
To evaluate the power of prenatal 2-D ultrasound examination in the 2nd trimester as a method of choice for accurate diagnosis of annular pancreas.


METHODS
Co-incidence of the double bubble sign (often accompanying gastroduodenal dilatation) together with a hyperechogenic band around the duodenum (corresponding with the tissue of annular pancreas) was used as a diagnostic criterion. Findings from postnatal surgery served for verification.


RESULTS
From 7,897 screened pregnancies, annular pancreas was proven in the cases where both signs were present, but never without the hyperechogenic band (N(1) = 3, N(2) = 3, p < or = 0.05). Sensitivity and specificity were 100%.


CONCLUSIONS
More multicentric studies are required to test this approach. The following diagnostic strategy is reasonable at the present time: when the double bubble sign is discovered, always suspect annular pancreas and look for the second sign: hyperechogenic bands around the duodenum. Also look for known associated anomalies, and vice versa, if any of associated anomalies are noted, also search specifically for the signs of annular pancreas.
Dankovcik
Robert
R
P.J. Safarik University, Kosice, Slovak Republic. dankovcik@mail.pvt.sk
Jirasek
Jan E
JE
Kucera
Eduard
E
Feyereisl
Jaroslav
J
Radonak
Jozef
J
Dudas
Marek
M
D000328:Adult; D003937:Diagnosis, Differential; D004380:Duodenal Obstruction / Q000151:congenital / Q000000981:diagnostic imaging*; D004386:Duodenum / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008403:Mass Screening; D010179:Pancreas / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D011247:Pregnancy; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000592:standards*