Myocarditis due to oral flurbiprofen use.
We report a 23-year-old man presenting with chest pain. He denoted skin eruptions on his hands, lips, mouth, and penis 24 to 36 hours after he had taken flurbiprofen 10 days ago. Detailed examination showed an ulcerated, pitching lesion with a dimension of approximately 2x2 cm on his penis; however, other explained skin lesions were ameliorated. ST elevations were present in the electrocardiogram. Cardiac biomarkers gradually rose. The scintigraphy showed myocardial hypoperfusion in the inferoseptal wall. This phenomenon is a rare case of myocarditis due to hypersensitivity reaction. In the case of nonspecific angina pectoris accompanied by electrocardiogram changes, drug-induced myocarditis must hold a place in differential diagnoses.
Uzkeser
Mustafa
M
Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
Emet
Mucahit
M
Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
Aslan
Sahin
S
Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey. Electronic address: sahinaslan29@hotmail.com.
Cakir
Zeynep
Z
Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
Turkyılmaz
Sule
S
Department of Emergency Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
Aksakal
Enbiya
E
Department of Cardiology, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
Seven
Bedri
B
Department of Nucleer Medicine, Ataturk University, School of Medicine, 25090 Erzurum, Turkey.
D000284:Administration, Oral; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005480:Flurbiprofen / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000139:chemically induced*; D055815:Young Adult
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005480:Flurbiprofen