title: Bioproduction of sorbicillin derivatives from marine Trichoderma sp.
abstract: The variability of sorbicillin derivatives production by marine Trichoderma sp., isolated from the sponge Agelas dispar J., was studied using six different culture media to find a good medium for biomass production, particularly of trichodimerol, bislongiquinolide and bisvertinol. A simple and rapid convenient method for identification, quantification and validation of the sorbicillin derivatives in ethyl acetate extracts has been applied by using RP-HPLC coupled with diode array detection.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt. aabelazim@yahoo.co.uk
authors.forename: Ahmed
authors.initials: A
authors.lastname: Abdel-Lateff
mesh_terms: D000475:Alkenes / Q000737:chemistry / Q000378:metabolism; D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D012118:Resorcinols / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D012623:Seawater / Q000382:microbiology; D018629:Spectrometry, Mass, Secondary Ion; D014242:Trichoderma / Q000502:physiology*
chemical_list: D000475:Alkenes; D001952:Bridged-Ring Compounds; D006575:Heterocyclic Compounds, 3-Ring; D012118:Resorcinols; C518568:bisvertinol; C099299:trichodimerol; C473616:sorbicillin