title: Therapeutic drug monitoring of voriconazole in a child with invasive aspergillosis requiring extracorporeal membrane oxygenation.
abstract: We describe a patient with invasive pulmonary aspergillosis on extracorporeal membrane oxygenation therapy in which therapeutic drug monitoring and individualization of therapy by measuring voriconazole plasma concentrations were performed.
authors.affiliation: Department of Clinical Pharmacy, Nijmegen University Centre for Infectious Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. r.bruggemann@akf.umcn.nl
authors.forename: Roger J M
authors.initials: RJ
authors.lastname: Brüggemann
authors.forename: Tim
authors.initials: T
authors.lastname: Antonius
authors.forename: Arno van
authors.initials: Av
authors.lastname: Heijst
authors.forename: Peter M
authors.initials: PM
authors.lastname: Hoogerbrugge
authors.forename: David M
authors.initials: DM
authors.lastname: Burger
authors.forename: Adilia
authors.initials: A
authors.lastname: Warris
mesh_terms: D000935:Antifungal Agents / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy*; D002675:Child, Preschool; D016903:Drug Monitoring; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D008297:Male; D011743:Pyrimidines / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D014230:Triazoles / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole