title: Comparison of antibacterial activity of three fluorides- and zinc-releasing commercial glass ionomer cements on strains of mutans streptococci: an in vitro study.
abstract: The purpose of present study was to investigate the antibacterial activity of three commercially available fluoride- and zinc-releasing glass ionomer cements on strains of mutans streptococci. Three glass ionomers (Fuji II Conventional, Fuji II Light Cure, and Fuji IX) were used. The antibacterial effect of glass ionomer cements were estimated by anaerobically growing mutans streptococci on a selective medium by inoculating human saliva and measuring the inhibition zones around the glass ionomer discs on the medium. Fluoride and zinc release were measured and compared with the antibacterial activity. The results, when statistically analyzed, showed a direct correlation between fluoride release and antibacterial activity, but there was no correlation between zinc release and antibacterial activity.
authors.affiliation: Department of Pediatric Dentistry, College of Dental Sciences and Hospital, Bapuji Dental College and Hospital, Davangere-577 004, India. tanmay5634@yahoo.co.in
authors.forename: K K
authors.initials: KK
authors.lastname: Shashibhushan
authors.forename: N
authors.initials: N
authors.lastname: Basappa
authors.forename: V V
authors.initials: VV
authors.lastname: Subba Reddy
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000737:chemistry; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000737:chemistry; D015169:Colony Count, Microbial; D003692:Delayed-Action Preparations / Q000737:chemistry; D003793:Dental Restoration, Permanent; D016503:Drug Delivery Systems; D005459:Fluorides / Q000008:administration & dosage* / Q000737:chemistry; D005899:Glass Ionomer Cements / Q000737:chemistry / Q000627:therapeutic use*; D008826:Microbial Sensitivity Tests; D012117:Resins, Synthetic / Q000737:chemistry / Q000627:therapeutic use*; D013295:Streptococcus mutans / Q000187:drug effects; D015032:Zinc / Q000008:administration & dosage* / Q000737:chemistry
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D003692:Delayed-Action Preparations; C079765:Fuji II LC cement; D005899:Glass Ionomer Cements; D012117:Resins, Synthetic; C110713:fuji IX; D015032:Zinc; D005459:Fluorides