title: Antibacterial effect of N-Naphtylen Diamine Platinum (II) Choloride as novel compound.
abstract: The present study synthesized N-Naphtylen Diamine Platinum (II) Chloride (NDPC) as a novel compound and tested ability of it regarding inhibition of cell division in some bacteria. Present results indicate that NDPC could act as antimitotic compound. It was inhibited growth of some microorganism as experimental organisms. The most antimitotic effect was seen in pseudomonas aeurginosa that treated by 15 mg mL(-1). Application of NDPC in all concentrations also was inhibited division and growth of other bacterial cells. Although Escherichia coli is less sensitive to NDPC than others, but also inhibition of growth is significant in E. coli.
authors.affiliation: Department of Biology, Faculty of Science, Cell and Molecular Lab, Bu-Ali Sina University, Hamedan, Iran.
authors.forename: Abdolkarim H
authors.initials: AH
authors.lastname: Chehregani
authors.forename: Seyed Javad
authors.initials: SJ
authors.lastname: Sabounchi
authors.forename: Vida
authors.initials: V
authors.lastname: Jodaian
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D017606:Chlorine Compounds / Q000737:chemistry* / Q000494:pharmacology*; D003959:Diamines / Q000737:chemistry*; D050296:Microbial Viability / Q000187:drug effects; D017671:Platinum Compounds / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D017606:Chlorine Compounds; D003959:Diamines; D017671:Platinum Compounds