Inflammatory morphea in the context of Raynaud phenomenon.
A 37-year-old woman presented with a one-year history of asymptomatic, red-brown patches and plaques on the abdomen and extremities, in the context of Raynaud phenomenon and anti-centromere antibodies. Two biopsy specimens confirmed the diagnosis of inflammatory morphea. Even in the absence of initial symptoms to support systemic disease, patients presenting with morphea in the setting of Raynaud phenomenon or anti-centromere antibodies deserve close surveillance for the possibility of CREST syndrome and systemic sclerosis.
Abbasi
Naheed
N
Department of Dermatology, New York University, USA.
Firoz
Bahar
B
Bossenbroek
Nicole M
NM
Meehan
Shane A
SA
Kamino
Hideko
H
Franks
Andrew G
AG
D000328:Adult; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D017675:CREST Syndrome / Q000175:diagnosis; D002503:Centromere / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007249:Inflammation; D008193:Lyme Disease / Q000175:diagnosis; D011928:Raynaud Disease / Q000150:complications* / Q000276:immunology; D012594:Scleroderma, Localized / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D012595:Scleroderma, Systemic / Q000175:diagnosis
D001323:Autoantibodies; D001324:Autoantigens