[The role of the pathologist in the diagnosis of metastases from urological malignancies].
Metastases are sometimes the first revelation of urologic cancers. The role of the pathologist in case metastatic disease of unknown origin is to affirm the malignant character of the lesion; provide histological information for possible origins; and to give histological therapeutic arguments. In most of the cases the histological analysis based on cellular morphology is sufficient to suspect a particular origin. In case of poor differentiated carcinoma in addition to the histological analysis, the immunohistochemical study allows the detection of various specific antigens. In this review we approach the various morphological criteria and the interest of the various antibodies to confirm the urologic origin of a metastasis.
Molinié
V
V
Service de Pathologie, Hôpital Saint Joseph, Paris, France. vmolinie@hopital-saint-joseph.org
D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology; D010336:Pathology; D010819:Physician's Role; D014571:Urologic Neoplasms / Q000473:pathology*