title: Semiparametric analysis of panel count data with correlated observation and follow-up times.
abstract: This paper discusses regression analysis of panel count data that often arise in longitudinal studies concerning occurrence rates of certain recurrent events. Panel count data mean that each study subject is observed only at discrete time points rather than under continuous observation. Furthermore, both observation and follow-up times can vary from subject to subject and may be correlated with the recurrent events. For inference, we propose some shared frailty models and estimating equations are developed for estimation of regression parameters. The proposed estimates are consistent and have asymptotically a normal distribution. The finite sample properties of the proposed estimates are investigated through simulation and an illustrative example from a cancer study is provided.
authors.affiliation: Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH 43210, USA. xhe@cph.osu.edu
authors.forename: Xin
authors.initials: X
authors.lastname: He
authors.forename: Xingwei
authors.initials: X
authors.lastname: Tong
authors.forename: Jianguo
authors.initials: J
authors.lastname: Sun
mesh_terms: D001699:Biometry; D003627:Data Interpretation, Statistical; D006801:Humans; D008137:Longitudinal Studies; D015233:Models, Statistical; D012008:Recurrence; D012044:Regression Analysis; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy