The role of manix in the management of idiopathic oligospermia. A pilot study at the Lagos University Teaching Hospital.
OBJECTIVE
To assess the usefulness of Manix in the management of men with idiopathic oligospermia.


METHODS
The study involved 55 infertile men with idiopathic oligospermia. Thirty-five patients were administered oral 600 mg of manix for 13 weeks and 20 were put on oral 1000 IU of vitamin E for 13 weeks. Semen analysis and the sex hormone profiles were done as baseline and then repeated at 3 and 6 months.


RESULTS
There were statistically significant improvements in semen parameters in the patients on Manix . No improvement was noted in the other group on vit E. There was however no significant difference in pregnancy rates in the two groups.


CONCLUSIONS
Manix may play a role in the management of patients with idiopathic olligospermia. However, large scale double blind controlled trials are needed to confirm the findings in this preliminary study.
Tijani
K H
KH
Urology unit, Dept of Surgery, College of Medicine, University of Lagos.
Adegoke
K
K
Oluwole
A A
AA
Ogunlewe
J
J
D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000097:blood / Q000188:drug therapy*; D008517:Phytotherapy / Q000379:methods*; D010865:Pilot Projects; D010936:Plant Extracts / Q000627:therapeutic use*; D012661:Semen / Q000187:drug effects; D016037:Single-Blind Method; D013739:Testosterone / Q000097:blood
D010936:Plant Extracts; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone