title: Oral versus intravenous administration of cyclophosphamide: a case report.
abstract: BACKGROUND
  Cyclophosphamide, an alkylating agent, has been used as an immunosuppressant in the treatment of various autoimmune disorders and malignancies. It is highly capable of reducing T and B lymphocytes.
  
  
  METHODS
  Regular blood tests are important to detect bone marrow suppression. The risk of opportunistic infection such as pneumonia secondary to pneumocystic carinii increases drastically with lymphopaenia. Hence, prophylactic co-trimoxazole is frequently prescribed as long as patients are on cyclophosphamide.
  
  
  CONCLUSIONS
  The benefits and toxicity risks of intravenous versus oral administration of cyclophosphamide are described in this article.
authors.affiliation: Department of Nephrology, St James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK. kenwu@doctors.org.uk.
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Wu
authors.forename: Chung
authors.initials: C
authors.lastname: Kwok
authors.forename: Aishin
authors.initials: A
authors.lastname: Lok