Update on infectious diseases in pediatric solid organ transplantation.
OBJECTIVE
Numerous recent advances have been made in the field of infectious diseases and pediatric solid organ transplant.


RESULTS
Although many studies contain somewhat small cohorts of individuals, when summarized together they contribute significantly to our knowledge about pediatric solid organ transplant, especially regarding risk factors for infection, management of BK virus nephropathy, the use of live viral vaccines, and consideration for rare infections as well as donor-derived infections.


CONCLUSIONS
In sum, these recent advances in infection in the field of pediatric solid organ transplant will help decrease infection, thus improving morbidity and mortality, as well as transplant outcomes, especially by decreasing direct (graft injury) and indirect (immune upregulation) effects on organ transplantation. This review will focus on recent advances in the field of infectious diseases in pediatric solid organ transplant by highlighting some of the most important and interesting articles in the field within the past few years.
Kotton
Camille Nelson
CN
Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. ckotton@partners.org
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001428:Bacterial Vaccines; D002648:Child; D002675:Child, Preschool; D003141:Communicable Diseases / Q000209:etiology* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D005657:Fungal Vaccines; D006801:Humans; D015994:Incidence; D007223:Infant; D017053:Infection Control; D016377:Organ Transplantation / Q000009:adverse effects*; D016052:Protozoan Vaccines; D012307:Risk Factors; D014611:Vaccination
D000890:Anti-Infective Agents; D001428:Bacterial Vaccines; D005657:Fungal Vaccines; D016052:Protozoan Vaccines