title: Langerhans cell histiocytosis involving the liver of a male smoker: a case report.
abstract: BACKGROUND
  Langerhans' cell histiocytosis is a proliferative histiocytic disorder of unknown cause originating from dendritic cells.
  
  
  METHODS
  The authors report a case of Langerhans' cell histiocytosis in a 48-year-old man with multisystemic disease presentation, including liver involvement.
  
  
  CONCLUSIONS
  Hepatic involvement is an uncommon feature in this rare disease and there is no consensus on the most effective therapeutic approach.
authors.affiliation: Department of Oncology, Portuguese Institute of Oncology Francisco Gentil, EPE, Porto, Portugal. joanasavva@gmail.com
authors.forename: Joana
authors.initials: J
authors.lastname: Savva-Bordalo
authors.forename: Margarida
authors.initials: M
authors.lastname: Freitas-Silva