title: A convenient three-component reaction leading to the synthesis of polysubstituted cyclohexene derivatives.
abstract: A three-component reaction of beta-nitrostyrene, arylmethylidenemalononitrile and malononitrile catalyzed by imidazole produced the corresponding polysubstituted cyclohexene derivatives in moderate to good yields under mild conditions. A further improvement of this three-component reaction has also been achieved by starting from a commercially available aromatic aldehyde, nitromethane and malononitrile to give the products in moderate yields.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China.
authors.forename: Xiao-Yang
authors.initials: XY
authors.lastname: Guan
authors.forename: Min
authors.initials: M
authors.lastname: Shi
mesh_terms: D053138:Cyclohexenes / Q000138:chemical synthesis* / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D053138:Cyclohexenes; D007093:Imidazoles; C052568:cyclohexene; C029899:imidazole