title: Correlation of postoperative epidural analgesia with morbidity and mortality following total knee replacement in Medicare patients.
abstract: It is unclear whether perioperative epidural analgesia is associated with a decrease in mortality in patients who undergo orthopedic procedures. We examined 35,878 patients' data obtained from a random sample of Medicare beneficiaries who underwent elective total knee replacement. Division of patients into 2 groups was based on presence or absence of billing for postoperative epidural analgesia. Outcomes assessed were death and major morbidity 30 days after surgery. Multivariate regression analysis revealed no between-groups difference in mortality 30 days after surgery. Postoperative epidural analgesia was not associated with lower incidence of mortality or major morbidity in Medicare patients who underwent elective total knee replacement.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA. chwu@jhmi.edu
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Wu
authors.forename: James S
authors.initials: JS
authors.lastname: Demeester
authors.forename: Robert
authors.initials: R
authors.lastname: Herbert
authors.forename: David N
authors.initials: DN
authors.lastname: Maine
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Rowlingson
authors.forename: Lee A
authors.initials: LA
authors.lastname: Fleisher
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015360:Analgesia, Epidural; D019645:Arthroplasty, Replacement, Knee / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D006278:Medicare; D009017:Morbidity; D015999:Multivariate Analysis; D011182:Postoperative Care; D014481:United States