title: Multisyringe flow injection system for solid-phase extraction coupled to liquid chromatography using monolithic column for screening of phenolic pollutants.
abstract: In this work a fast, automatic solid-phase extraction procedure hyphenated to HPLC-UV is proposed for screening of priority phenolic pollutants in waters at ng mL(-1) levels. A flow through column, containing polystyrene-divinylbenzene sorbent, was incorporated to a multisyringe flow injection system (MSFIA), where the sample loading and analyte elution were carried out after computer control. The MSFIA system also directed the eluent to fill the injection loop of the chromatograph, coupling the sample preparation to its determination. High enrichment factors were attained for phenol and ten of its derivatives (mean value 176 for 50 mL of sample), with LOD values lower than 1 ng mL(-1) for the maximum volume of sample used (100mL). For all analytes, mean recoveries between 89 and 103% were obtained for different water matrices. Certified reference material and a contaminated soil (RTC-CRM 112) were also tested successfully. The determination frequency was 4-10h(-1), providing an automatic, fast and reliable tool for water quality and environmental monitoring.
authors.affiliation: Faculdade de Farmácia, REQUIMTE, Serviço de Química-Física, Universidade do Porto, Porto, Portugal.
authors.forename: Hugo M
authors.initials: HM
authors.lastname: Oliveira
authors.forename: Marcela A
authors.initials: MA
authors.lastname: Segundo
authors.forename: José L F C
authors.initials: JL
authors.lastname: Lima
authors.forename: Victor
authors.initials: V
authors.lastname: Cerdà
mesh_terms: D001331:Automation; D002853:Chromatography, Liquid / Q000295:instrumentation* / Q000379:methods; D003199:Computer Systems; D004784:Environmental Monitoring / Q000379:methods; D007700:Kinetics; D013058:Mass Spectrometry / Q000295:instrumentation; D008956:Models, Chemical; D019800:Phenol / Q000032:analysis*; D012989:Soil Pollutants / Q000032:analysis; D052616:Solid Phase Extraction / Q000295:instrumentation* / Q000379:methods; D014867:Water / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification; D014881:Water Supply
chemical_list: D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; D014867:Water; D019800:Phenol