title: Incidence of and survival from oligodendroglioma in Denmark, 1943-2002.
abstract: We established the nationwide, population-based incidence of oligodendroglioma in Denmark during 59 years of monitoring and compared the overall survival of patients with oligodendroglial tumors during the periods 1943-1977 and 1978-2002. On the basis of reports in the Danish Cancer Registry, 1,304 cases of oligodendroglioma were included in the study. We calculated sex- and age-specific incidence rates in 5-year age intervals and for 5-year calendar periods. Overall survival was estimated by the Kaplan-Meier method. In the period 1943-2002, the incidence rate of oligodendroglioma was less than 1 case per 100,000 person-years, but varied somewhat when viewed across isolated periods. Comparison of the incidence rate before and after the introduction of CT scanning did not reveal a significant difference in the incidence rate. The median survival increased from 1.4 years (95% confidence interval [CI], 1.0-1.6) to 3.4 years (95% CI, 2.6-4.2) during the period of study. The overall incidence of oligodendroglioma showed a relatively stable pattern over nearly 60 years of monitoring. Overall survival improved significantly during the study period, which could partly be due to improved diagnostic methods and treatment options.
authors.affiliation: Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.
authors.forename: Malene Schjønning
authors.initials: MS
authors.lastname: Nielsen
authors.forename: Helle Collatz
authors.initials: HC
authors.lastname: Christensen
authors.forename: Michael
authors.initials: M
authors.lastname: Kosteljanetz
authors.forename: Christoffer
authors.initials: C
authors.lastname: Johansen
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001932:Brain Neoplasms / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D053208:Kaplan-Meier Estimate; D008297:Male; D009837:Oligodendroglioma / Q000453:epidemiology*; D012042:Registries; D055815:Young Adult