title: Subthalamic role on the generation of spikes in temporal epilepsy.
abstract: We report the electrophysiological findings in an unusual patient with temporal lobe epilepsy and subthalamic stimulators implanted to treat Parkinson's disease. Temporal and frontotemporal spikes were observed in the EEG. Temporal spikes spread to the STN in a 40% of cases, involving simultaneously all contacts. Frontotemporal spikes showed more frequent STN propagation (70%), shorter delays, and progressive spread from ventral to dorsal contacts than temporal spikes. These results suggest that a direct fronto-subthalamic pathway might account for the fast propagation of the frontotemporal spikes to the ventral STN.
authors.affiliation: Department of Neurology and Neurosurgery, Clínica Universitaria and Medical School, and Neurosciences Division, CIMA University of Navarra, Pamplona, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Urrestarazu
authors.forename: Jorge
authors.initials: J
authors.lastname: Iriarte
authors.forename: Manuel
authors.initials: M
authors.lastname: Alegre
authors.forename: Jorge
authors.initials: J
authors.lastname: Guridi
authors.forename: María Cruz
authors.initials: MC
authors.lastname: Rodríguez-Oroz
authors.forename: José
authors.initials: J
authors.lastname: Obeso
authors.forename: César
authors.initials: C
authors.lastname: Viteri
authors.forename: Julio
authors.initials: J
authors.lastname: Artieda
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D004525:Efferent Pathways / Q000503:physiopathology; D004558:Electric Stimulation / Q000009:adverse effects; D004569:Electroencephalography / Q000379:methods; D004833:Epilepsy, Temporal Lobe / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000628:therapy; D020531:Subthalamic Nucleus / Q000503:physiopathology*