title: Analysis of 238U, 232Th, 222Rn, and 220Rn in different medical drug preparations by using CR-39 and LR-115 typE II SSNTDs and resulting radiation doses to adult patients.
abstract: Uranium (238U) and thorium (232Th) concentrations as well as radon (222Rn) and thoron (220Rn) alpha activities per unit volume have been measured inside 18 medical drugs (4 liquid and 14 solid materials), widely prescribed by doctors to the Moroccan adult patients, by using CR-39 and LR-115 type II solid state nuclear track detectors (SSNTDs). The measured 238U, 232Th, 222Rn, and 220Rn concentrations ranged from (4.7 +/- 0.1) mBq L-1 to (14.3 +/- 0.7) mBq L-1, (0.32 +/- 0.02) mBq L-1 to (2.7 +/- 0.2) mBq L-1, (4.7 +/- 0.2) Bq L-1 to (14.3 +/- 0.7) Bq L-1, and (0.32 +/- 0.02) Bq L-1 to (2.7 +/- 0.2) Bq L-1 for the medical drug samples studied, respectively. These radionuclides were also measured inside the preparations of the solid medical drugs studied. The influence of the drinking water nature and pollution on the concentrations of these radionuclides inside the considered medical drug preparations was investigated. Annual committed equivalent doses due to 238U, 232Th, and 222Rn were evaluated in the human body compartments of adult patients from the ingestion of the medical drug preparations studied. The maximum total committed effective dose due to 238U, 232Th, and 222Rn from the ingestion of the studied medical drug preparations, prepared from unpolluted waters, by adult patients was found equal to 1.44 microSv y.
authors.affiliation: Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, BP 2390, University Cadi Ayyad, Marrakech, Morocco. misdaq@ucam.ac.ma
authors.forename: M A
authors.initials: MA
authors.lastname: Misdaq
authors.forename: M
authors.initials: M
authors.lastname: Karime
mesh_terms: D003101:Collodion; D003642:Deanol; D004338:Drug Combinations; D004339:Drug Compounding; D004435:Eating; D005971:Glutamates; D055553:Prescription Drugs / Q000737:chemistry; D011829:Radiation Dosage; D011874:Radiometry; D011886:Radon / Q000032:analysis*; D013910:Thorium / Q000032:analysis*; D014501:Uranium / Q000032:analysis*
chemical_list: D004338:Drug Combinations; D005971:Glutamates; D055553:Prescription Drugs; D003642:Deanol; C043253:deanol aceglutamate; D014501:Uranium; D013910:Thorium; D003101:Collodion; D011886:Radon