title: Brazilian genome sequencing projects: state of the art.
abstract: This review covers all Brazilian Genome, EST and Metagenome Projects, Sequencing Networks' history and structure, and patents related to Brazilian Genome Projects, beginning with the first genome sequenced in this country, i.e. the 9a5c strain of Xylella fastidiosa CVC, up till the recently sequenced 1002 strain of Corynebacterium pseudotuberculosis, which was done with a mixed strategy that included both traditional Sanger methodology and Avant Garde 454 Life Sciences pyrosequencing technology. Almost 90% of all genomic research that has been done in Latin America is a product of Brazil's effort to support and stimulate OMICs in our country. Consequently, we gave special attention to patents registered by Brazilian genome networks and/or Brazilian scientists involved in genomics, transcriptomics, proteomics, EST, and metagenome projects, as well as in the development of bioinformatics software and techniques.
authors.affiliation: Departamento de Biologia Geral do Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais. Avenida Antônio Carlos, 6627. Campus Pampulha. Belo Horizonte, Minas Gerais. CEP 31.270-010, Brasil. vasco@icb.ufmg.br
authors.forename: Eduardo Righi Capanema
authors.initials: ER
authors.lastname: Xavier
authors.forename: Beatriz Parreiral Xavier
authors.initials: BP
authors.lastname: Capanema
authors.forename: Jerônimo Conceicão
authors.initials: JC
authors.lastname: Ruiz
authors.forename: Guilherme
authors.initials: G
authors.lastname: Oliveira
authors.forename: Roberto
authors.initials: R
authors.lastname: Meyer
authors.forename: Vivian
authors.initials: V
authors.lastname: D'Afonseca
authors.forename: Anderson
authors.initials: A
authors.lastname: Miyoshi
authors.forename: Vasco
authors.initials: V
authors.lastname: Azevedo
mesh_terms: D001938:Brazil; D019295:Computational Biology / Q000379:methods; D016925:Corynebacterium pseudotuberculosis / Q000235:genetics; D020224:Expressed Sequence Tags; D016680:Genome, Bacterial / Q000235:genetics; D023281:Genomics / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D044167:Xylella / Q000235:genetics