title: [Forecast on shelf life of Chinese Angelica based on its chemical components variation].
abstract: OBJECTIVE
  To predict the shelf life of Chinese Angelica by investigating the stability of its active components.
  
  
  METHODS
  The classic homeothermia method was used for forecast the shelf life, and HPLC was applied for quantitative determination of chemical compounds in Chinese Angelica.
  
  
  RESULTS
  The correlation equations, thermal constant at ambient temperature (k(25 degrees C)) and shelf life (t(0.9)) for coniferyl ferulate and Z-Ligustilide were lgk = -5152. 1/T + 13.8 (r = 0.9985), 3. 33 x 10(-4), 13 d and lgk = -4064.6/T + 10.4 (r = 0.9997), 5.91 x 10(-4), 7 d, respectively.
  
  
  CONCLUSIONS
  The shelf life of Chinese Angelica has been established, which suggests that it is very important for ensuring the safety and efficacy of Chinese crude drug.
authors.affiliation: Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
authors.forename: Jing-jing
authors.initials: JJ
authors.lastname: Xie
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.forename: Shao-ping
authors.initials: SP
authors.lastname: Li
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry*; D004355:Drug Stability; D004356:Drug Storage; D004365:Drugs, Chinese Herbal / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal