Easily made single-walled carbon nanotube surface microelectrodes for neuronal applications.
The present work examines the feasibility of a simple method for using single-walled carbon nanotubes (SWNT) to fabricate multielectrode arrays (MEA) for electrophysiological recordings. A suspension of purified SWNTs produced by arc discharged was directly deposited onto standard platinum electrodes. The in vitro impedance and electrochemical characterizations demonstrated the enhanced electrical properties of the SWNT microelectrode array. To test its functionality we performed extracellular ganglion cell recordings in isolated superfused rabbit retinas. Our results showed that SWNT based electrode arrays have potential advantages over metal electrodes and can be successfully used to record the single and multi-unit activity of ganglion cell populations.
Gabriel
Gemma
G
Instituto de Microelectrónica de Barcelona, IMB-CNM (CSIC), Bellaterra, Barcelona, Spain.
Gómez
Rodrigo
R
Bongard
Markus
M
Benito
Nuria
N
Fernández
Eduardo
E
Villa
Rosa
R
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D066298:In Vitro Techniques; D008839:Microelectrodes; D036103:Nanotechnology / Q000295:instrumentation*; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure*; D011817:Rabbits; D015203:Reproducibility of Results; D012165:Retinal Ganglion Cells / Q000502:physiology*; D012680:Sensitivity and Specificity
D037742:Nanotubes, Carbon