title: [The spread and biological properties of epidemic influenza viruses A and B strains circulating in the 2006-2007 season in Russia].
abstract: The epidemic upsurge of influenza morbidity in the 2006-2007 season in Russia was caused by the active circulation of influenza A(H1N1), A(H3N2) and B viruses. The Center for Ecology and Epidemiology of Influenza studied 259 epidemic strains; All the strains were isolated on MDCK cell cultures. Influenza A(H1N1) viruses (n = 101) were antigenic variants of the references A/New Caledonia/20/99 and A/Solomon Islands/3/06. Influenza A(H3N2) viruses (n = 98) were antigenic variants of the references A/California/7/07 and A/Wisconsin/67/05. Twenty four influenza B virus strains were drift variants of the reference BI Shanghai/361/02 - lineage B/Yamagata/16188 and 36 were related to A/Malaysia/2506/05 - lineage B/Victoria/2/87). All the isolated strains actively interacted with human erythrocytes of the blood groups 0(I) and A(II) and very slightly with chicken ones. Twenty-two (48%) A(H1N1) strains and 19 (35%) A(H3N2) strains which were resistant to rimantafine were revealed. Studies of the donor sera collected in Moscow and the Moscow Region, the Jewish Autonomous Region, and Primorye revealed antibodies to today's strains; the level of antibodies in the preepidemic period depended on the region and strain. A study of changes in antibody formation in different periods of an epidemic process showed a rise in antibodies mainly to influenza A and B virus strains circulating in this period.
authors.forename: V T
authors.initials: VT
authors.lastname: Ivanova
authors.forename: Ia E
authors.initials: IaE
authors.lastname: Kurochkina
authors.forename: E I
authors.initials: EI
authors.lastname: Burtseva
authors.forename: T A
authors.initials: TA
authors.lastname: Oskerko
authors.forename: S V
authors.initials: SV
authors.lastname: Trushakova
authors.forename: E S
authors.initials: ES
authors.lastname: Shevchenko
authors.forename: E G
authors.initials: EG
authors.lastname: Cherkasov
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: R O
authors.initials: RO
authors.lastname: Matiushina
authors.forename: L V
authors.initials: LV
authors.lastname: Kolobukhina
authors.forename: E L
authors.initials: EL
authors.lastname: Feodoritova
authors.forename: A N
authors.initials: AN
authors.lastname: Slepushkin
mesh_terms: D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D000956:Antigens, Viral / Q000235:genetics / Q000276:immunology; D000998:Antiviral Agents / Q000494:pharmacology; D004285:Dogs; D040961:Genetic Drift; D006384:Hemagglutination; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D009981:Influenza B virus / Q000187:drug effects / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D007251:Influenza, Human / Q000453:epidemiology* / Q000276:immunology* / Q000821:virology; D017720:Molecular Epidemiology; D012299:Rimantadine / Q000494:pharmacology; D012426:Russia / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D000998:Antiviral Agents; D012299:Rimantadine