title: [Enhancement pattern of peripheral lung carcinoma:comparison between contrast-enhanced ultrasonography and contrast-enhanced computed tomography].
abstract: OBJECTIVE
  To compare the enhancement pattern of low mechanical index contrast-enhanced ultrasonography (CEUS) in peripheral lung carcinoma with contrast-enhanced helical CT (CECT).
  
  
  METHODS
  Thirty-five patients with peripheral lung carcinoma underwent CEUS performed with the contrast agent SonoVue at a low mechanical index contrast specific mode and CECT performed with the contrast agent Ultravist at a standard biphasic helical CT scanning protocol. The enhancement pattern related to tumor vascularity was analyzed.
  
  
  RESULTS
  By using contrast-enhanced sonography, hyper-enhancement patterns were manifested in 57.1% (20/35) of the lesions and hypo-enhancement in 40% (14/35); both not significantly different from those manifested by using CECT [42.9% (15/35) and 54.3% (19/35) of the lesions respectively, both P > 0.05]. By using CEUS, inhomogeneous enhancement pattern rate in the lesions was 68.6% (24/35) and the homogeneous enhancement rate was 28.6%(10/35), both not significantly different from those of the CECT group [74.3% (26/35) and 22.9% (8/35) respectively, both P > 0.05]. The non-enhancement rates of CEUS and CECT group were both 2.9% (1/35). The enhancement intensity dB value of the CEUS group was positively correlated with the CT value of the CECT tumors (r = 0.836, P < 0.001).
  
  
  CONCLUSIONS
  The diagnostic value of contrast-enhanced sonography is similar to that of enhancement CT in detecting peripheral lung carcinoma's vascularity.
authors.affiliation: Department of Ultrasonography, Zhejiang University, Zhejiang 310009, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Wen
authors.forename: Xue-ming
authors.initials: XM
authors.lastname: Liu
authors.forename: Zhi-yan
authors.initials: ZY
authors.lastname: Luo
authors.forename: Juan-juan
authors.initials: JJ
authors.lastname: Chen
authors.forename: Yu-rong
authors.initials: YR
authors.lastname: Hong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement; D055752:Small Cell Lung Carcinoma / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods; D018084:Ultrasonography, Interventional
chemical_list: D003287:Contrast Media