Synthetic approaches to the 2007 new drugs.
New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 19 NCEs marketed in 2007.
Liu
Kevin K-C
KK
Pfizer Inc, La Jolla, CA 92037, USA.
Sakya
Subas M
SM
O'Donnell
Christopher J
CJ
Li
Jin
J
D015195:Drug Design; D006801:Humans; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013997:Time Factors
D004364:Pharmaceutical Preparations