title: [Risk factors of hypertension in IgA nephropathy].
abstract: OBJECTIVE
  To explore the risk factors of hypertension in patients with IgA nephropathy in South China.
  
  
  METHODS
  The clinical and renal pathological data of 280 primary IgA nephropathy patients diagnosed by biopsy were analyzed to extinguish the risk factors of hypertension.
  
  
  RESULTS
  A total of 96 patients were suffered with hypertension (34.3%). A single-variable analysis showed that the age (>or= 40 years), body weight (>or= 60 kg), absence of macrohematuria, duration of disease (>or= 60 months), blood urea nitrogen >or= 8 mmol/L, serum creatinine (>or= 133 micromol/L), hyperuricaemia, degree of 24 h-proteinuria (>or= 1.5 g), segmental glomerular lesions (>or= 25%), globe glomerular sclerosis (>or= 10%), tubular atrophy (>or= 25%), interstitial fibrosis (>or= 25%), interstitial inflammation (>or= 25%) and arteriole hypertrophy (>or= 10%) were all risk factors related to hypertension; multivariate logistic regression analysis showed that serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors.
  
  
  CONCLUSIONS
  Many factors were related the hypertension in patients with IgA nephropathy, while serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors of hypertension.
authors.affiliation: Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
authors.forename: Shen-heng
authors.initials: SH
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Wen-jian
authors.initials: WJ
authors.lastname: Wang
authors.forename: Xin-ling
authors.initials: XL
authors.lastname: Liang
authors.forename: Shuang-xin
authors.initials: SX
authors.lastname: Liu
authors.forename: Zhi-ming
authors.initials: ZM
authors.lastname: Ye
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Chao-sheng
authors.initials: CS
authors.lastname: He
authors.forename: Yun-feng
authors.initials: YF
authors.lastname: Xia
authors.forename: Jian-chao
authors.initials: JC
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001835:Body Weight; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D006977:Hypertension, Renal / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors
chemical_list: D003404:Creatinine