Prompt remission of severe SLE with only three doses of rituximab infusion and low dose steroid: the first case report from Indonesia.
A 31-year-old Chinese lady presented with severe SLE with nephrotic syndrome, anemia, leucopenia and thrombocytopenia, skin lesions, and joint inflammation after failing previous standard therapy. After treatment with three infusions of rituximab she showed immediate improvements regarding clinical and laboratory parameters. She received no cytotoxic drugs and remained well for at least 7 months, despite stopping prednisolone.
Mardjuadi
A
A
Departments of Rheumatology, National Development University, Jakarta, Indonesia. reuma@cbn.net.id
Soedirman
M
M
Utoyo
Buddy
B
Rasker
J J
JJ
D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D058846:Antibodies, Monoclonal, Murine-Derived; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage*; D007214:Indonesia; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage*; D012074:Remission Induction; D000069283:Rituximab
D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D005938:Glucocorticoids; D007155:Immunologic Factors; D000069283:Rituximab; D011239:Prednisolone