title: A randomised trial comparing the H Pipelle with the standard Pipelle for endometrial sampling at 'no-touch' (vaginoscopic) hysteroscopy.
abstract: OBJECTIVE
  To evaluate the effectiveness and tolerance of H Pipelle compared with the standard Pipelle as an endometrial biopsy device at outpatient 'no-touch' hysteroscopy.
  
  
  METHODS
  A prospective randomised trial carried out in an outpatient diagnostic hysteroscopy clinic.
  
  
  METHODS
  A large undergraduate teaching hospital.
  
  
  METHODS
  Sixty women investigated for abnormal menstruation in an outpatient diagnostic hysteroscopy clinic.
  
  
  METHODS
  Prospective randomised trial comparing the H Pipelle with the standard Pipelle de Cornier.
  
  
  METHODS
  Adequacy of the biopsy specimens and women's experience.
  
  
  RESULTS
  Ninety-three percent (H Pipelle) and 87% (Pipelle) of the biopsy specimens were judged to be adequate for histological diagnosis (P > 0.05). However, obtaining endometrial sampling with the H Pipelle was significantly quicker (median times: 39 seconds [H Pipelle] and 102 seconds [Pipelle], P < 0.0001) and less painful (median visual analogue scale score: 1 [H Pipelle] and 5 [Pipelle], P = 0.011).
  
  
  CONCLUSIONS
  The H Pipelle not only makes it possible to perform hysteroscopy and endometrial biopsy with minimal instrumentation but is also associated with a shorter biopsy time and less discomfort than the standard Pipelle without any loss of biopsy adequacy.
authors.affiliation: University Department of Obstetrics and Gynaecology, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
authors.forename: S
authors.initials: S
authors.lastname: Madari
authors.forename: N
authors.initials: N
authors.lastname: Al-Shabibi
authors.forename: P
authors.initials: P
authors.lastname: Papalampros
authors.forename: A
authors.initials: A
authors.lastname: Papadimitriou
authors.forename: A
authors.initials: A
authors.lastname: Magos
mesh_terms: D001007:Anxiety / Q000209:etiology; D001706:Biopsy / Q000295:instrumentation*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D020702:Hysteroscopes; D015907:Hysteroscopy / Q000379:methods*; D008599:Menstruation Disturbances / Q000473:pathology*; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D011446:Prospective Studies