title: Vincristine-induced eccrine squamous syringometaplasia.
abstract: Eccrine squamous syringometaplasia is a histologic finding associated with chemotherapy administration and other cutaneous diseases. Concentration of the chemotherapeutic agents is believed to effect toxic changes in these epithelial structures. We report the first case of vincristine-induced eccrine squamous syringometaplasia in a 12-year-old patient undergoing treatment for rhabdomyosarcoma.
authors.affiliation: Division of Dermatology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0028, USA. lacey.m.thomas@vanderbilt.edu
authors.forename: Lacey Mitchell
authors.initials: LM
authors.lastname: Thomas
authors.forename: Melinda
authors.initials: M
authors.lastname: Mohr
authors.forename: Michael
authors.initials: M
authors.lastname: Smith
authors.forename: Alan
authors.initials: A
authors.lastname: Boyd
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D004439:Eccrine Glands; D005260:Female; D006801:Humans; D012208:Rhabdomyosarcoma / Q000188:drug therapy*; D013544:Sweat Gland Neoplasms / Q000139:chemically induced* / Q000473:pathology; D018252:Syringoma / Q000139:chemically induced* / Q000473:pathology; D014625:Vaginal Neoplasms / Q000188:drug therapy*; D014750:Vincristine / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine