[Management of non-malignant results in core needle biopsy of breast lesions].
OBJECTIVE
To study the strategy of management of non-malignant results in core needle biopsy (CNB) of breast lesions.


METHODS
Consecutive 2654 breast lesions underwent CNB with 14-gauge automated needles. 1130 lesions with diagnosis of non-malignant breast lesions examined by CNB were followed up. The histological diagnosis of CNB, subsequent excision or repeat CNB, and the follow-up for cases without repeat biopsy were studied.


RESULTS
Among the 1130 non-malignant breast lesions examined by CNB, 530 underwent re-biopsy and 73 cases of carcinoma were found. 491 lesions were followed up for 1 - 38 months (median, 13.3 months) and another 4 cases of carcinoma were found during the follow-up. 109 cases were lost to follow-up. 57.9% (22/38) of the atypical ductal hyperplasia, 22.2% (4/18) of the atypical ductal cells, 27.9% (24/86) of the papillary lesions, and 90.0% (9/10) of the suspicious carcinoma diagnosed by CNB were re-diagnosed as breast cancer finally.


CONCLUSIONS
Repeat biopsy is required for the high-risk lesions diagnosed by breast CNB. Excision can be avoided on the benign lesions whose CNB diagnosis is consistent with those by physical examination and imaging.
Fan
Zhao-Qing
ZQ
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Breast Cancer Center, Peking University School of Oncology, Beijing Cancer Hospital, Beijing 100142, China. zhqfan@sina.com
Ouyang
Tao
T
Li
Jin-Feng
JF
Wang
Tian-Feng
TF
Xie
Yun-Tao
YT
Fan
Tie
T
Zhang
Zhe
Z
Lin
Ben-Yao
BY
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary