title: Four cases of venous thromboembolism associated with olanzapine.
abstract: OBJECTIVE
  Psychiatric disorders and treatment with conventional antipsychotic medications have been associated with venous thromboembolism, but only a few data on recent antipsychotics such as olanzapine are available.
  
  
  METHODS
  We describe four subjects treated with olanzapine who developed venous thromboembolism, and were hospitalized at the University Hospital in Hradec Kralove during the period 2004-2006.
  
  
  RESULTS
  We found a combination of several clinical and laboratory risk factors in our patients.
  
  
  CONCLUSIONS
  A cohort study or case-control studies are needed to better elucidate the possible role of olanzapine in etiopathogenesis of venous thromboembolism.
authors.affiliation: First Department of Internal Medicine, Charles University in Prague, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic.
authors.forename: Radovan
authors.initials: R
authors.lastname: Maly
authors.forename: Jiri
authors.initials: J
authors.lastname: Masopust
authors.forename: Ladislav
authors.initials: L
authors.lastname: Hosak
authors.forename: Ales
authors.initials: A
authors.lastname: Urban
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy; D012563:Schizophrenia, Paranoid / Q000150:complications / Q000188:drug therapy; D014463:Ultrasonography; D054556:Venous Thromboembolism / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine