Development of a new semi-quantitative non-invasive method for evaluating ventricular stroke work.
OBJECTIVE
Ventricular stroke work (SW) is one of the best indices to evaluate ventricular function, however, the SW monitoring mainly depends on the invasive method with the artery catheter. In this paper, our aim is to develop a new semi-quantitative non-invasive method for evaluating ventricular SW.


METHODS
The multiple gated cardiac blood pool imaging was done in 25 patients with coronary artery disease and 12 normal controls. A new parameter, the relative stroke work (RSW) of left ventricle, was calculated using an equation derived from the principle of hydrodynamics. The left ventricular SW was analyzed by stroke volume (SV) and mean arterial pressure. Ejected fraction (EF), peak ejected rate (PER) and peak filling rate (PFR) were gotten with the routine software in imaging device.


RESULTS
The left ventricular RSW was linearly correlated with the SW. The RSW was related to the SV, EF, PER and PFR of the left ventricle. The RSW had regressive relation with SV and PER. The RSW in patients, same as SW, SV, EF, PFR and PER, was noticeably lower than that in normal controls, P<0.01.


CONCLUSIONS
The RSW is a potential and valuable clinical index for evaluation of the ventricular function.
Cheng
Mu-Hua
MH
Department of Nuclear medicine, Third Hospital Affiliated Sun Yat-sen University, Guangdong Province, China. marka@21c.com
Rao
Guo-Hui
GH
Zhou
Han-Jian
HJ
Xu
Jie-Hua
JH
Zhang
Feng
F
D001794:Blood Pressure; D055426:Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D013670:Sodium Pertechnetate Tc 99m; D012984:Software; D013318:Stroke Volume; D014003:Tin Polyphosphates; D016276:Ventricular Function
D019275:Radiopharmaceuticals; D014003:Tin Polyphosphates; D013670:Sodium Pertechnetate Tc 99m