title: Laboratory evaluation of dimethyl phthalate against Anopheles stephensi and Culex pipiens.
abstract: Two repellents includes Iranian and Merck dimethyl phthalate (DMP) were evaluated against Anopheles stephensi and Culex pipiens, using American Society for Testing and Material (ASTM) standard ED 951-83 procedure, a free choice method based on the variable dose-fixed time. Also a modified of ASTM method we used for determination of effective dosages of the repellents. In ASTM method there were no significant differences between the two repellents (Iranian and Merck's DMP) as indicated by the ED50 and ED95 values (p > 0.05). But, there were significant differences in repellent sensitivity between An. stephensi and Cx. pipiens at the ED95 level. In modified ASTM method there were no significant differences between the two repellents against An. stephensi, as indicated by the ED50 values (p > 0.05). But, there are significant differences between the two repellents against Cx. pipence based on ED50 value. Results of this study showed that the Iranian synthesized DMP has necessary potential and specificity to compare with Merck manufactured product.
authors.affiliation: Military Health Research Center, Military Medicine Institute, Baqiyatallah University of Medical Science, Molla Sadra Stree, P.O. Box 19945/581, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Khoobdel
authors.forename: Mohamad Ali
authors.initials: MA
authors.lastname: Oshaghi
authors.forename: Neamatollah
authors.initials: N
authors.lastname: Jonaidi
authors.forename: Mansoreh
authors.initials: M
authors.lastname: Shayeghi
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Abaei
authors.forename: Younes
authors.initials: Y
authors.lastname: Panahi
authors.forename: Hassan
authors.initials: H
authors.lastname: Vatandoost
authors.forename: Hadi
authors.initials: H
authors.lastname: Vatani
authors.forename: Ali
authors.initials: A
authors.lastname: Tajik
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Saeedfar
mesh_terms: D000818:Animals; D000852:Anopheles / Q000187:drug effects*; D001733:Bites and Stings / Q000517:prevention & control*; D003465:Culex / Q000187:drug effects*; D005260:Female; D006801:Humans; D007302:Insect Repellents / Q000494:pharmacology*; D010795:Phthalic Acids / Q000494:pharmacology*
chemical_list: D007302:Insect Repellents; D010795:Phthalic Acids; C024629:dimethyl phthalate