title: Boron polylactide nanoparticles exhibiting fluorescence and phosphorescence in aqueous medium.
abstract: Difluoroboron dibenzoylmethane-polylactide, BF(2)dbmPLA, a biocompatible polymer-luminophore conjugate was fabricated as nanoparticles. Spherical particles <100 nm in size were generated via nanoprecipitation. Intense blue fluorescence, two-photon absorption, and long-lived room temperature phosphorescence (RTP) are retained in aqueous suspension. The nanoparticles were internalized by cells and visualized by fluorescence microscopy. Luminescent boron biomaterials show potential for imaging and sensing.
authors.affiliation: Department of Chemistry, University of Virginia, McCormick Road, Charlottesville, Virginia 22904, USA.
authors.forename: Anne
authors.initials: A
authors.lastname: Pfister
authors.forename: Guoqing
authors.initials: G
authors.lastname: Zhang
authors.forename: Jessica
authors.initials: J
authors.lastname: Zareno
authors.forename: Alan F
authors.initials: AF
authors.lastname: Horwitz
authors.forename: Cassandra L
authors.initials: CL
authors.lastname: Fraser
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D003460:Crystallization / Q000379:methods; D008029:Lighting / Q000379:methods*; D008163:Luminescent Measurements / Q000379:methods*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods; D010316:Particle Size; D011091:Polyesters / Q000737:chemistry*; D013499:Surface Properties; D014867:Water / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D046911:Macromolecular Substances; D011091:Polyesters; D014867:Water; C033616:poly(lactide)