title: [Thyroid and pregnancy].
abstract: Pregnancy is associated with an increased requirement of hormone secretion by the thyroid, within the first weeks after conception. To this greater demand to occurs, pregnancy induces a series of physiological changes that affect thyroid function and, consequently, the tests of glandular function. For normal pregnant women living in areas with a sufficient supply of iodine, this challenge regarding the adjustment of thyroid hormone releases to this new state of equilibrium and its maintenance until the end of pregnancy it meets no difficulties. However, among women with impaired thyroid function due to some thyroid disease or among women residing in areas with an insufficient iodine supply, this does not occur. The management of thyroid dysfunction during gestation requires special considerations, since both hypothyroidism and hyperthyroidism can lead to maternal and fetal complications. In addition, thyroid nodules are detected at reasonable frequency among pregnant women, a fact that requires a differential diagnosis between benign and malignant growths during the pregnancy itself.
authors.affiliation: Divisão de Endocrinologia, Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil. lmzmacie@fmrp.usp.br
authors.forename: Léa Maria Zanini
authors.initials: LM
authors.lastname: Maciel
authors.forename: Patrícia K R
authors.initials: PK
authors.lastname: Magalhães
mesh_terms: D005260:Female; D006044:Goiter, Nodular / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D007037:Hypothyroidism / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D007455:Iodine / Q000172:deficiency; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000503:physiopathology; D013959:Thyroid Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D013961:Thyroid Gland / Q000378:metabolism / Q000503:physiopathology; D013963:Thyroid Hormones / Q000378:metabolism; D016606:Thyroid Nodule / Q000503:physiopathology
chemical_list: D013963:Thyroid Hormones; D007455:Iodine