title: Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids--a case report and review of the literature.
abstract: Rhodococcus equi has emerged as an opportunistic pathogen usually causing necrotizing pneumonia in immunosuppressed patients but has been found increasingly in extrapulmonary sites. We report the 1st case of R. equi brain abscess in a patient receiving corticosteroid monotherapy and review the literature for risk factors and sites of infection.
authors.affiliation: Department of Neurology, Johns Hopkins University Hospital, Baltimore, MD 21287, USA.
authors.forename: Ricardo Horacio
authors.initials: RH
authors.lastname: Roda
authors.forename: Mary
authors.initials: M
authors.lastname: Young
authors.forename: Joseph
authors.initials: J
authors.lastname: Timpone
authors.forename: Jessica
authors.initials: J
authors.lastname: Rosen
mesh_terms: D000193:Actinomycetales Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D001922:Brain Abscess / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D013902:Radiography, Thoracic; D016929:Rhodococcus equi / Q000302:isolation & purification*; D013909:Thorax / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D015242:Ofloxacin; D011241:Prednisone