title: Building biomedical web communities using a semantically aware content management system.
abstract: Web-based biomedical communities are becoming an increasingly popular vehicle for sharing information amongst researchers and are fast gaining an online presence. However, information organization and exchange in such communities is usually unstructured, rendering interoperability between communities difficult. Furthermore, specialized software to create such communities at low cost-targeted at the specific common information requirements of biomedical researchers-has been largely lacking. At the same time, a growing number of biological knowledge bases and biomedical resources are being structured for the Semantic Web. Several groups are creating reference ontologies for the biomedical domain, actively publishing controlled vocabularies and making data available in Resource Description Framework (RDF) language. We have developed the Science Collaboration Framework (SCF) as a reusable platform for advanced structured online collaboration in biomedical research that leverages these ontologies and RDF resources. SCF supports structured 'Web 2.0' style community discourse amongst researchers, makes heterogeneous data resources available to the collaborating scientist, captures the semantics of the relationship among the resources and structures discourse around the resources. The first instance of the SCF framework is being used to create an open-access online community for stem cell research-StemBook (http://www.stembook.org). We believe that such a framework is required to achieve optimal productivity and leveraging of resources in interdisciplinary scientific research. We expect it to be particularly beneficial in highly interdisciplinary areas, such as neurodegenerative disease and neurorepair research, as well as having broad utility across the natural sciences.
authors.affiliation: Initiative in Innovative Computing, Harvard University, 60 Oxford Street, Cambridge, MA, USA. sudeshna_das@harvard.edu
authors.forename: Sudeshna
authors.initials: S
authors.lastname: Das
authors.forename: Lisa
authors.initials: L
authors.lastname: Girard
authors.forename: Tom
authors.initials: T
authors.lastname: Green
authors.forename: Louis
authors.initials: L
authors.lastname: Weitzman
authors.forename: Alister
authors.initials: A
authors.lastname: Lewis-Bowen
authors.forename: Tim
authors.initials: T
authors.lastname: Clark
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration; D003628:Database Management Systems; D016208:Databases, Factual; D006801:Humans; D033181:Information Dissemination; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet / Q000295:instrumentation / Q000458:organization & administration*; D012660:Semantics; D012984:Software