title: [Management of non-malignant results in core needle biopsy of breast lesions].
abstract: OBJECTIVE
  To study the strategy of management of non-malignant results in core needle biopsy (CNB) of breast lesions.
  
  
  METHODS
  Consecutive 2654 breast lesions underwent CNB with 14-gauge automated needles. 1130 lesions with diagnosis of non-malignant breast lesions examined by CNB were followed up. The histological diagnosis of CNB, subsequent excision or repeat CNB, and the follow-up for cases without repeat biopsy were studied.
  
  
  RESULTS
  Among the 1130 non-malignant breast lesions examined by CNB, 530 underwent re-biopsy and 73 cases of carcinoma were found. 491 lesions were followed up for 1 - 38 months (median, 13.3 months) and another 4 cases of carcinoma were found during the follow-up. 109 cases were lost to follow-up. 57.9% (22/38) of the atypical ductal hyperplasia, 22.2% (4/18) of the atypical ductal cells, 27.9% (24/86) of the papillary lesions, and 90.0% (9/10) of the suspicious carcinoma diagnosed by CNB were re-diagnosed as breast cancer finally.
  
  
  CONCLUSIONS
  Repeat biopsy is required for the high-risk lesions diagnosed by breast CNB. Excision can be avoided on the benign lesions whose CNB diagnosis is consistent with those by physical examination and imaging.
authors.affiliation: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Breast Cancer Center, Peking University School of Oncology, Beijing Cancer Hospital, Beijing 100142, China. zhqfan@sina.com
authors.forename: Zhao-Qing
authors.initials: ZQ
authors.lastname: Fan
authors.forename: Tao
authors.initials: T
authors.lastname: Ouyang
authors.forename: Jin-Feng
authors.initials: JF
authors.lastname: Li
authors.forename: Tian-Feng
authors.initials: TF
authors.lastname: Wang
authors.forename: Yun-Tao
authors.initials: YT
authors.lastname: Xie
authors.forename: Tie
authors.initials: T
authors.lastname: Fan
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.forename: Ben-Yao
authors.initials: BY
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary