Bio-inspired arene cis-dihydroxylation by a non-haem iron catalyst modeling the action of naphthalene dioxygenase.
Reported in this paper is the first example of a biomimetic iron complex, ([Fe(II)(TPA)(NCMe)(2)](2+) (TPA = tris(2-pyridylmethyl)amine), that catalyses the cis-dihydroxylation of an aromatic double bond, mimicking the action of the non-haem iron enzyme naphthalene dioxygenase and shedding light on its possible mechanism of action.
Feng
Yan
Y
Department of Chemistry and Center for Metals in Biocatalysis, University of Minnesota, Minneapolis, MN, USA.
Ke
Chun-Yen
CY
Xue
Genqiang
G
Que
Lawrence
L
D032701:Biomimetics; D002384:Catalysis; D049308:Dioxygenases; D005296:Ferrous Compounds / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D006900:Hydroxylation; D009097:Multienzyme Complexes / Q000737:chemistry*; D009284:Naphthols / Q000737:chemistry; D019159:Nonheme Iron Proteins / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry; D010104:Oxygen Radioisotopes / Q000737:chemistry; D010105:Oxygenases / Q000737:chemistry*
D005296:Ferrous Compounds; D009097:Multienzyme Complexes; D009284:Naphthols; D019159:Nonheme Iron Proteins; D016877:Oxidants; D010104:Oxygen Radioisotopes; D006861:Hydrogen Peroxide; D010105:Oxygenases; D049308:Dioxygenases; C038703:naphthalene dioxygenase