title: Treatment of iatrogenic and traumatic tracheal disruptions.
abstract: OBJECTIVE
  The optimal management of tracheal disruptions is still controversial. It is usually postulated that lesions wider than 1 or 2 centimetres and/or lesions of full-thickness should be treated by surgery at an early stage. Such a statement is not supported by any proven evidence. On the contrary, the conservative management of such injuries has also produced very good results according to recent reports. The aim of this study is to investigate whether conservative treatment can be safely used for wide tracheal lacerations and to assess any possible association between clinical features and modality of treatment.
  
  
  METHODS
  Records of all patients with iatrogenic and traumatic tracheal disruptions observed between January 1992 and December 2006 were collected and retrospectively reviewed. Data regarding mechanism of injury, clinical and morphological features and modalities of treatment were registered. All possible associations between clinical features and modalities of treatment were investigated.
  
  
  RESULTS
  23 patients were observed overall. There were 6 males and 17 females with a median age of 58 years (range 20-84 yrs). 15 patients had undergone single tube intubation. One patient had his trachea injured during an esophagectomy. Ruptures were secondary to blunt (n = 5) and open (n = 2) trauma in 7 patients. Lesions varied in length between 1 and 7 centimetres (median length 3 centimetres) and all were full-thickness. The time interval until diagnosis varied between 0 and 72 hours (median 6 hours). Respiratory failure was evident in 7 patients. 16 patients (69.5%) with lacerations ranging in length between 1 and 5.5 centimetres (median length 2.75 cm) underwent conservative treatment. Seven patients (30.5%) underwent surgery. The follow up was completed for 16 patients and varied between 15 and 105 months (median 22.5). One patient died after surgical treatment. No mortality or late major sequelae were registered after conservative treatment. Female sex, absence of respiratory failure and delayed diagnosis was associated with the conservative treatment.
  
  
  CONCLUSIONS
  Conservative treatment can play a major role even in cases of wide tracheal lacerations. Clinical rather than morphological features should be regarded as main criteria for treatment. The conservative treatment is particularly indicated in the case of stable respiratory parameters independent of the size and the depth of the lesion.
authors.affiliation: Unit of Thoracic Surgery, San Martino University Hospital, Genoa, Italy. giacomo.leoncini@hsanmartino.it
authors.forename: G
authors.initials: G
authors.lastname: Leoncinii
authors.forename: L
authors.initials: L
authors.lastname: Iurilli
authors.forename: L
authors.initials: L
authors.lastname: Boni
authors.forename: G
authors.initials: G
authors.lastname: Blanco
authors.forename: P
authors.initials: P
authors.lastname: De Bellis
authors.forename: G
authors.initials: G
authors.lastname: Catrambone
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D007442:Intubation, Intratracheal / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D019838:Neck Injuries / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies; D014132:Trachea / Q000293:injuries*; D016896:Treatment Outcome; D014950:Wounds, Penetrating / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D055815:Young Adult