Drug delivery by soft matter: matrix and vesicular carriers.
The increasing need for drug delivery systems that improve specificity and activity and at the same time reduce toxicity to ensure maximum treatment safety has led to the development of a great variety of drug vectors. Carriers based on soft matter have particularly interesting characteristics. Herein we present the current standing of the research in this area, and focus on two main families, namely matrix systems and vesicles. We outline the structure, properties, and potential applications of these vectors, and discuss their main advantages and drawbacks in their synthesis.
Soussan
Elodie
E
Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique, UMR CNRS 5623, Université Paul Sabatier, 31062 Toulouse Cedex 4, France.
Cassel
Stéphanie
S
Blanzat
Muriel
M
Rico-Lattes
Isabelle
I
D003102:Colloids / Q000138:chemical synthesis / Q000737:chemistry; D050091:Dendrimers / Q000138:chemical synthesis / Q000737:chemistry; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry; D016503:Drug Delivery Systems; D008081:Liposomes / Q000138:chemical synthesis / Q000737:chemistry; D008823:Micelles; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D013501:Surface-Active Agents / Q000138:chemical synthesis / Q000737:chemistry
D003102:Colloids; D050091:Dendrimers; D004337:Drug Carriers; D008081:Liposomes; D008823:Micelles; D011108:Polymers; D013501:Surface-Active Agents