title: Effects of a ferment soy product on the adipocyte area reduction and dyslipidemia control in hypercholesterolemic adult male rats.
abstract: BACKGROUND
  Available data on the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on circulating lipids and adiposity are not completely settled. This study aimed to observe the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on central obesity and dyslipidemia control in Wistar adult male rats.
  
  
  METHODS
  Over a period of 8 weeks, animals had "ad libitum" food intake and water consumption as well as body weight and food consumption was monitored. The animals were assigned to four different experimental groups: Control Group (C); Control + Fermented Product Group (CPF); Hypercholesterolemic diet group (H); and Hypercholesterolemic + Fermented Product Group (HPF). The HPF and CPF groups received an intragastric administration of 1 ml of fermented product daily. After the experimental period the animals were killed by decapitation, blood was collected to measure cholesterol, triglycerides and HDL-cholesterol plasma concentration. Adipocyte circumference, lipolysis and lipogenis rates were measures using epididymal and retroperitoneal white adipose tissues.
  
  
  RESULTS
  The results demonstrated that 1 ml/day/rat of the fermented soy product promoted important benefits such as reduced cholesterolemia in hypercholesterolemic diet group and the adipocyte circumference in both control and hypercholesterolemic diet group.
  
  
  CONCLUSIONS
  The fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti decreased circulating lipids levels and reduced adipocyte area in rats.
authors.affiliation: UFU/Federal University of Uberlândia, Uberlândia, Minas Gerais, Brasil. nadiacheik@terra.com.br
authors.forename: Nadia Carla
authors.initials: NC
authors.lastname: Cheik
authors.forename: Elizeu Antônio
authors.initials: EA
authors.lastname: Rossi
authors.forename: Ricardo Luís Fernandes
authors.initials: RL
authors.lastname: Guerra
authors.forename: Neuli Maria
authors.initials: NM
authors.lastname: Tenório
authors.forename: Cláudia Maria
authors.initials: CM
authors.lastname: Oller do Nascimento
authors.forename: Fabiana Pavan
authors.initials: FP
authors.lastname: Viana
authors.forename: Marla Simone Jovenasso
authors.initials: MS
authors.lastname: Manzoni
authors.forename: Iracilda Zeponni
authors.initials: IZ
authors.lastname: Carlos
authors.forename: Patrícia
authors.initials: P
authors.lastname: Leão da Silva
authors.forename: Regina Célia
authors.initials: RC
authors.lastname: Vendramini
authors.forename: Ana Raimunda
authors.initials: AR
authors.lastname: Dâmaso
mesh_terms: D017667:Adipocytes / Q000473:pathology*; D000818:Animals; D001835:Body Weight; D016984:Enterococcus faecium; D005285:Fermentation; D006937:Hypercholesterolemia / Q000178:diet therapy*; D007778:Lactobacillus; D008066:Lipolysis; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D045730:Soy Foods