title: Cation selectivity of ionophores based on tripodal thiazole derivatives on benzene scaffold.
abstract: The synthesis and potentiometric evaluation of new 1,3,5-tris(thiazolylcarbethoxy)-2,4,6-trimethylbenzene (3), 1,3,5-tris(thiazolylhydroxy)-2,4,6-trimethylbenzene (4), 1,3,5-tris(thiazolylmethyl)-2,4,6-trimethylbenzene (5), and 1,3,5-tris(thiazolylphenyl)-2,4,6-trimethylbenzene (6), toward mono and divalent cations under various pH conditions are outlined. The ion-selective properties of the newly synthesized compounds were studied by measuring the potentiometric responses of the 3-, 4-, 5-, and 6-based membrane electrodes to alkali metal, alkaline earth metal, ammonium, and transition metal ions, under various pH conditions. The 3-based electrode exhibited a Nernstian response to ammonium and potassium under alkaline pH conditions, while the other three electrodes showed a poor potentiometric performance. All electrodes showed substantial responses to silver ion under acidic condition, but there was almost nil response to other transition metal ions (Fe(2+), Co(2+), Zn(2+), Ni(2+), Pb(2+), Cd(2+), Cu(2+) and Hg(2+)). The 3- and 5-based electrodes resulted in near Nernstian responses (51.3mV and 59.5mV/pAg(+), respectively) with low detection limits (approximately 100ppt), while the 4- and 6-based ones showed sub-Nernstian below 40mV/pAg(+). The results were interpreted with semi-empirically modeled structures.
authors.affiliation: Department of Applied Chemistry, Kyungpook National University, Daegu 702-701, Republic of Korea. kimhs@knu.ac.kr
authors.forename: Hong-Seok
authors.initials: HS
authors.lastname: Kim
authors.forename: Dong-Hyun
authors.initials: DH
authors.lastname: Kim
authors.forename: Ki Soo
authors.initials: KS
authors.lastname: Kim
authors.forename: Jun-Hyeak
authors.initials: JH
authors.lastname: Choi
authors.forename: Heung-Jin
authors.initials: HJ
authors.lastname: Choi
authors.forename: Sung-Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Jun Ho
authors.initials: JH
authors.lastname: Shim
authors.forename: Geun Sig
authors.initials: GS
authors.lastname: Cha
authors.forename: Hakhyun
authors.initials: H
authors.lastname: Nam