MR relaxation in multiple sclerosis.
This article provides an overview of relaxation times and their application to normal brain and brain and cord affected by multiple sclerosis. The goal is to provide readers with an intuitive understanding of what influences relaxation times, how relaxation times can be accurately measured, and how they provide specific information about the pathology of MS. The article summarizes significant results from relaxation time studies in the normal human brain and cord and from people who have multiple sclerosis. It also reports on studies that have compared relaxation time results with results from other MR techniques.
MacKay
A L
AL
Department of Radiology, University of British Columbia, Vancouver, BC, Canada. mackay@physics.ubc.ca
Vavasour
I M
IM
Rauscher
A
A
Kolind
S H
SH
Mädler
B
B
Moore
G R W
GR
Traboulsee
A L
AL
Li
D K B
DK
Laule
C
C
D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009103:Multiple Sclerosis / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology; D013995:Time