title: Resin glycoside constituents of Ipomoea pes-caprae (beach morning glory).
abstract: Eight new resin glycosides, pescapreins X-XVII (1-8), were isolated from a lipophilic fraction of an ethanol extract of the entire plant of beach morning glory, Ipomoea pes-caprae. Their structures were elucidated by spectroscopic data analysis and by chemical transformation. These compounds were evaluated biologically in terms of cancer cell line cytotoxicity, antibacterial and antifungal activity, and effects on the mu-opioid receptor.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
authors.forename: Hongwen
authors.initials: H
authors.lastname: Tao
authors.forename: Xiaojiang
authors.initials: X
authors.lastname: Hao
authors.forename: Jinggen
authors.initials: J
authors.lastname: Liu
authors.forename: Jian
authors.initials: J
authors.lastname: Ding
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Fang
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
mesh_terms: D000818:Animals; D002240:Carbohydrate Sequence; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005227:Fatty Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D027741:Ipomoea / Q000737:chemistry*; D007941:Leukemia P388; D051379:Mice; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D017450:Receptors, Opioid, mu / Q000187:drug effects; D012116:Resins, Plant / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D005227:Fatty Acids; D006027:Glycosides; D017450:Receptors, Opioid, mu; D012116:Resins, Plant