title: The role of outer membrane proteins of Ornithobacterium rhinotracheale in attachment to chicken tracheal epithelium.
abstract: Ornithobacterium rhinotracheale (ORT) infections cause major losses to the poultry industry. In search for factors implicated in the pathogenesis of ORT infections, the role of outer membrane proteins (OMPs) in the interaction of ORT with chicken tracheal epithelium was investigated. For this purpose, immune sera were prepared against total extracted OMPs, whole cell bacteria and three major OMPs of 45, 53 and 70 kDa and used in bacterial adherence inhibition assay. The results showed antibodies against a 53 kDa OMP significantly (p < or = 0.05) inhibited the bacterial adherence to chicken tracheal epithelium up to 78%.
authors.affiliation: Department of Pathobiology, School of Veterinary Medicine, Shahid Chamran University, Ahwaz, Iran.
authors.forename: K
authors.initials: K
authors.lastname: Nofouzi
authors.forename: M R
authors.initials: MR
authors.lastname: Seyfi Abad Shapouri
authors.forename: M
authors.initials: M
authors.lastname: Jamshidian
authors.forename: M
authors.initials: M
authors.lastname: Mayahi
authors.forename: M
authors.initials: M
authors.lastname: Ghaforian
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D002645:Chickens; D004848:Epithelium / Q000382:microbiology*; D045246:Ornithobacterium / Q000378:metabolism*; D011201:Poultry Diseases / Q000382:microbiology* / Q000473:pathology*; D011485:Protein Binding; D014132:Trachea / Q000382:microbiology*
chemical_list: D001425:Bacterial Outer Membrane Proteins