title: Steroid-sensitive nephrotic syndrome in two families.
abstract: Few reports of familial cases of steroid-sensitive nephrotic syndrome (SSNS) are available. Of 123 children with SSNS, four cases in two families are presented. Two sisters and a father and his daughter developed SSNS. The incidence of SSNS siblings in Japan seems to be similar to the incidence reported in other countries. SSNS in two generations is rare. To our knowledge, cases of SSNS in a parent and a child in Japan have not been reported.
authors.affiliation: Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura-shi, Chiba, 285-8741, Japan. motoyan@basil.ocn.ne.jp.
authors.forename: Osamu
authors.initials: O
authors.lastname: Motoyama
authors.affiliation: Department of Pediatrics, Saiseikai Yokohama-shi Tobu Hospital, Kanagawa, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Sugawara
authors.affiliation: Department of Pediatrics, Saiseikai Yokohama-shi Tobu Hospital, Kanagawa, Japan.
authors.forename: Michihiro
authors.initials: M
authors.lastname: Hatano
authors.affiliation: Department of Pediatrics, Saiseikai Yokohama-shi Tobu Hospital, Kanagawa, Japan.
authors.forename: Tomoo
authors.initials: T
authors.lastname: Fujisawa
authors.affiliation: Department of Pediatrics, Social Insurance Sagamino Hospital, Kanagawa, Japan.
authors.forename: Kikuo
authors.initials: K
authors.lastname: Iitaka
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People / Q000706:statistics & numerical data; D002648:Child; D005190:Family; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000208:ethnology / Q000235:genetics*; D010375:Pedigree; D012074:Remission Induction; D013256:Steroids / Q000627:therapeutic use*
chemical_list: D013256:Steroids