Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane column.
The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (K(IAM)) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.
Uekusa
Yoshinori
Y
Laboratory of Molecular Food Engineering and Global COE Program, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan.
Takeshita
Yuko
Y
Ishii
Takeshi
T
Nakayama
Tsutomu
T
D000872:Anthocyanins / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D005419:Flavonoids / Q000737:chemistry / Q000378:metabolism*; D008567:Membranes, Artificial; D010636:Phenols / Q000737:chemistry / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000737:chemistry / Q000378:metabolism*; D059808:Polyphenols
D000872:Anthocyanins; D005419:Flavonoids; D008567:Membranes, Artificial; D010636:Phenols; D010713:Phosphatidylcholines; D059808:Polyphenols