Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi.
Twelve new xanthones (1-12), a pair of new natural products (13 and 14), and 18 known related compounds were isolated from the resin of Garcinia hanburyi. The structures of 1-14 were elucidated by detailed spectroscopic analyses. A cytotoxic assay of the isolated compounds revealed that, with the exception of 2, these compounds were active against the HeLa tumor cell line.
Tao
Si-Jia
SJ
Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Zhangjiang, Shanghai 201203, People's Republic of China.
Guan
Shu-Hong
SH
Wang
Wei
W
Lu
Zhi-Qiang
ZQ
Chen
Guang-Tong
GT
Sha
Na
N
Yue
Qing-Xi
QX
Liu
Xuan
X
Guo
De-An
DA
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D002681:China; D004354:Drug Screening Assays, Antitumor; D029760:Garcinia / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D012116:Resins, Plant / Q000737:chemistry; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000972:Antineoplastic Agents, Phytogenic; D012116:Resins, Plant; D044004:Xanthones