Pancreatic panniculitis and carcinoma of the pancreas.
Pancreatic panniculitis is a rare complication of carcinoma of the pancreas, most often accompanying the rare acinar cystadenocarcinoma. It presents with painful erythematous subcutaneous nodules typically located on the leg. We present a case of a 79-year-old man with neuroendocrine carcinoma of the pancreas and liver metastasis, who developed painful subcutaneous nodules on his shins. Laboratory values included a raised lipase level with normal amylase level and peripheral eosinophilia. The patient was treated with nonsteroidal anti-inflammatory drugs, dexamethasone and antibiotics, with resolution of the dermatological symptoms.
Sagi
L
L
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel. lior115@gmail.com
Amichai
B
B
Barzilai
A
A
Weitzen
R
R
Trau
H
H
D000368:Aged; D001706:Biopsy; D003536:Cystadenocarcinoma / Q000150:complications*; D006801:Humans; D007868:Leg Dermatoses / Q000209:etiology* / Q000473:pathology; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications*; D015434:Panniculitis / Q000209:etiology* / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000473:pathology