The adjoint method for general EEG and MEG sensor-based lead field equations.
Most of the methods for the inverse source problem in electroencephalography (EEG) and magnetoencephalography (MEG) use a lead field as an input. The lead field is the function which relates any source in the brain to its measurements at the sensors. For complex geometries, there is no analytical formula of the lead field. The common approach is to numerically compute the value of the lead field for a finite number of point sources (dipoles). There are several drawbacks: the model of the source space is fixed (a set of dipoles), and the computation can be expensive for as much as 10,000 dipoles. The common idea to bypass these problems is to compute the lead field from a sensor point of view. In this paper, we use the adjoint method to derive general EEG and MEG sensor-based lead field equations. Within a simple framework, we provide a complete review of the explicit lead field equations, and we are able to extend these equations to non-pointlike sensors.
Vallaghé
Sylvain
S
INRIA, Projet Odyssée, Sophia Antipolis, France. Sylvain.Vallaghe@sophia.inria.fr
Papadopoulo
Théodore
T
Clerc
Maureen
M
D004569:Electroencephalography / Q000379:methods*; D015225:Magnetoencephalography / Q000379:methods*; D008954:Models, Biological