title: Pentafluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antiprotozoal activities of diarylamines.
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, Hönggerberg, HCI, Zürich, Switzerland.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Stump
authors.forename: Christian
authors.initials: C
authors.lastname: Eberle
authors.forename: W Bernd
authors.initials: WB
authors.lastname: Schweizer
authors.forename: Marcel
authors.initials: M
authors.lastname: Kaiser
authors.forename: Reto
authors.initials: R
authors.lastname: Brun
authors.forename: R Luise
authors.initials: RL
authors.lastname: Krauth-Siegel
authors.forename: Dieter
authors.initials: D
authors.lastname: Lentz
authors.forename: François
authors.initials: F
authors.lastname: Diederich
mesh_terms: D000588:Amines / Q000737:chemistry* / Q000494:pharmacology*; D000818:Animals; D000981:Antiprotozoal Agents; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D056890:Eukaryota / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000588:Amines; D000981:Antiprotozoal Agents; D004791:Enzyme Inhibitors; D013438:Sulfhydryl Compounds; D009247:NADH, NADPH Oxidoreductases; C049608:trypanothione reductase