Synthesis of bis-ureas from bis(o-nitrophenyl) carbonate.
A general method for the preparation of bis-ureas from bis(o-nitrophenyl) carbonate has been developed. Directional urea synthesis is achieved by sequential amine addition to bis(o-nitrophenyl) carbonate in two steps: in the first step bis(o-nitrophenyl) carbonate is reacted with benzylamine to form benzyl-o-nitrophenyl carbamate; in the second step the carbamate is reacted with a variety of diamines in toluene to yield bis-ureas.
Turoczi
Maria-Cristina
MC
POLITEHNICA University of Timisoara, Department of Applied Chemistry and Engineering of Organic and Natural Compounds, 300006 Timisoara, Piata Victoriei 2, Romania. cristina_turoczi@yahoo.com
Simon
Monika
M
Badea
Valentin
V
Csunderlik
Carol
C
D003959:Diamines / Q000737:chemistry; D009596:Nitrophenols / Q000737:chemistry*; D014508:Urea / Q000138:chemical synthesis* / Q000737:chemistry
D003959:Diamines; D009596:Nitrophenols; C006777:bis(4-nitrophenyl)carbonate; D014508:Urea