title: Electrochemical preparation and delivery of melanin-iron covered gold nanoparticles.
abstract: Attractive combination: Biopolymer-modified nanoparticles which combine magnetic properties with biocompatibility are prepared and delivered following a three-step strategy (see figure): i) Adsorption of thiol-capped metal nanoparticles on graphite, ii) electrochemical modification, iii) potential-induced delivery of the modified nanoparticles to the electrolyte. Thiol-capped gold nanoparticles modified with iron-melanin are attractive because they combine magnetic properties and biocompatibility. The biopolymer modified nanoparticles are prepared and delivered following a three step strategy: i) adsorption of thiol-capped metal nanoparticles on graphite, ii) electrochemical deposition of melanin-iron, iii) potential-induced delivery of the modified nanoparticles to the electrolyte.
authors.affiliation: Instituto de Investigaciones Fisicoquímicas, Teóricas y Aplicadas, Sucursal 4 Casilla de Correo 16 (1900), Universidad Nacional de La Plata- CONICET, Argentina.
authors.forename: Doris
authors.initials: D
authors.lastname: Grumelli
authors.forename: Carolina
authors.initials: C
authors.lastname: Vericat
authors.forename: Guillermo
authors.initials: G
authors.lastname: Benítez
authors.forename: José M
authors.initials: JM
authors.lastname: Ramallo-López
authors.forename: Lisandro
authors.initials: L
authors.lastname: Giovanetti
authors.forename: Félix
authors.initials: F
authors.lastname: Requejo
authors.forename: M Sergio
authors.initials: MS
authors.lastname: Moreno
authors.forename: Alejandro González
authors.initials: AG
authors.lastname: Orive
authors.forename: Alberto Hernández
authors.initials: AH
authors.lastname: Creus
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Salvarezza
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques; D004563:Electrochemistry / Q000379:methods; D006046:Gold / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008280:Magnetics; D008543:Melanins / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D010316:Particle Size; D013052:Spectrometry, X-Ray Emission; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013499:Surface Properties
chemical_list: D008543:Melanins; D013438:Sulfhydryl Compounds; D006046:Gold; D007501:Iron