title: [Cranial-orbital approach in the treatment of optic nerve glioma].
abstract: OBJECTIVE
  To summarize the experience in cranial-orbital approach in the treatment of optic nerve glioma.
  
  
  METHODS
  The clinical data of 35 patients with optic nerve glioma diagnosed by CT and MRI, 26 males and 9 females; aged 13 (1 - 54), with the main clinical presentations of visual defection and ex-ophthalmo and with the courses from 1 to 36 months, who underwent operation via the cranial-orbital approach 36 times, were analyzed. The diagnosis was confirmed by pathology after operation in 35 cases. Follow-up was conducted for 3 months to 8 years.
  
  
  RESULTS
  Total resection was achieved in 29 cases, and subtotal resection in 6 cases. The surgical complications included temporary cerebrospinal fluid rhinorrhea (2 cases) and cataract (1 cases), and no ocular movement dysfunction was found. The follow-up rate was 77.1% (27/35). Three cases suffered from recurrence, spinal metastasis was found in 1 case, and 1 case died.
  
  
  CONCLUSIONS
  resection of optic nerve glioma via cranial-orbital approach is effective. However, since residual tumor may remain in the optic nerve canal, post-operative radiation therapy is recommended.
authors.affiliation: Department of Neurosurgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
authors.forename: Tian-ming
authors.initials: TM
authors.lastname: Zhang
authors.forename: Yu-zhi
authors.initials: YZ
authors.lastname: An
authors.forename: Hao-cheng
authors.initials: HC
authors.lastname: Liu
authors.forename: Jiang-ping
authors.initials: JP
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D020339:Optic Nerve Glioma / Q000601:surgery*; D009915:Orbit / Q000601:surgery*