[Management of acne vulgaris: focus on clindamycin and zinc].
Topical antibiotics, especially clindamycin, are well-accepted in the treatment of mild to moderate acne. Combinations of clindamycin and other agents such as benzoyl peroxide, retinoids or zinc, are possibly superior to clindamycin monotherapy regarding efficacy and tolerability with the combination 1% clindamycin/5% benzoyl peroxide being particularly well-supported by evidence. Moreover, a recent study has shown that patients themselves prefer a complex of zinc acetate/clindamycin phosphate.
Korting
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HC
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, 80337, München. H.C.Korting@lrz.uni-muenchen.de
Schöllmann
C
C
D000152:Acne Vulgaris / Q000175:diagnosis* / Q000188:drug therapy*; D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D010818:Practice Patterns, Physicians' / Q000639:trends*; D015032:Zinc / Q000008:administration & dosage*
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D002981:Clindamycin; D015032:Zinc