title: Genetic polymorphism of 15 STR loci in central western Colombia.
abstract: Fifteen autosomal short tandem repeat (STR) loci were analyzed using the AmpFISTR Identifiler PCR Amplification Kit in 1944 samples of healthy unrelated individuals, born in the regions of Caldas, Quindio and Risaralda, Colombia. Allele frequencies and statistical parameters of forensic interest are presented for all markers (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA). All loci of the pooled data were in agreement with Hardy-Weinberg equilibrium, after Bonferroni correction. Comparisons with neighboring Latin American populations and Andalucia (Spain) revealed significant differences in allele distributions. Genetic data presented in this study can be used for routine forensic applications in the region.
authors.affiliation: Medical Genetic Laboratory of Universidad Tecnológica de Pereira, Colombia.
authors.forename: L
authors.initials: L
authors.lastname: Porras
authors.forename: L
authors.initials: L
authors.lastname: Beltrán
authors.forename: T
authors.initials: T
authors.lastname: Ortiz
authors.forename: P
authors.initials: P
authors.lastname: Sanchez-Diz
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
authors.forename: J
authors.initials: J
authors.lastname: Henao
mesh_terms: D000483:Alleles; D003105:Colombia; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D016172:DNA Fingerprinting / Q000379:methods; D044707:Forensic Sciences / Q000706:statistics & numerical data; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005843:Geography; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic; D011786:Quality Control; D012984:Software
chemical_list: D005819:Genetic Markers; D004247:DNA