A unique case of cortical myoclonus sensitive to visual stimuli in the peripersonal space.
Multimodal representation of peripersonal or near space has been demonstrated in the brain of the nonhuman primate through invasive electrophysiological experiments. Representation of peripersonal space in the human brain has been inferred from extinction experiments and functional imaging studies. We present a unique case of lower limb myoclonus in a patient with common variable immunodeficiency which is sensitive to visual stimuli in the peripersonal space and light touch. This case provides further evidence for near space representation in the human brain. We hypothesize that somatopically organized multimodal areas exist in the human brain which code for peripersonal space.
Parasivam
Sharavanan
S
Department of Neurology, Flinders Medical Centre, Bedford Park, Adelaide, South Australia. sharavanan.parasivam@fmc.sa.gov.au
Cowey
Max
M
Day
Bruce
B
Thyagarajan
Dominic
D
D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D004569:Electroencephalography; D004576:Electromyography; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D018482:Muscle, Skeletal / Q000294:innervation; D009207:Myoclonus / Q000175:diagnosis* / Q000503:physiopathology*; D010775:Photic Stimulation / Q000379:methods*; D012720:Severity of Illness Index; D013028:Space Perception; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult