Characterization and genotyping of strains of Francisella tularensis isolated in Bulgaria.
A tularaemia focus was detected in 1998 in Bulgaria, in an area where tularaemia had never been reported. The properties of Francisella tularensis subsp. holarctica strains isolated from 1998 to 2005 were studied. The strains showed heterogeneity, based on acid production from glycerol and erythromycin susceptibility. Genotyping by analysis of seven loci containing variable-number tandem repeats showed four genotypes among eight strains.
Marinov
Krustyu T
KT
Military Medical Academy, Georgy Sofiisky Blvd 3, Sofia, Bulgaria.
Georgieva
Elena D
ED
Military Medical Academy, Georgy Sofiisky Blvd 3, Sofia, Bulgaria.
Ivanov
Ivan N
IN
National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Kantardjiev
Todor V
TV
National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002031:Bulgaria / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D005604:Francisella tularensis / Q000145:classification / Q000235:genetics*; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D014406:Tularemia / Q000453:epidemiology / Q000382:microbiology
D000900:Anti-Bacterial Agents