An unusual presentation of infantile fibrosarcoma in a male newborn.
We describe a 10-day-old male presenting with drop foot and immobility in his right leg; no abnormality in physical examination had been found upon delivery or discharge. Magnetic resonance imaging showed a pelvic mass with an extension to the great sciatic foramen. Fine-needle aspiration biopsy revealed congenital infantile fibrosarcoma. He was started on vincristine, actinomycin-D, cyclophosphamide chemotherapy. However, he died soon after the second cycle due to veno-occlusive disease of the liver. Differential diagnosis of drop foot and immobility in lower extremity must include infiltrating neoplasms in pelvis.
Gülhan
Bora
B
Department of Pediatrics, Hacettepe University, Ankara, Turkey.
Küpeli
Serhan
S
Yalçin
Bilgehan
B
Akyüz
Canan
C
Büyükpamukçu
Münevver
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D017809:Fatal Outcome; D005354:Fibrosarcoma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D006504:Hepatic Veno-Occlusive Disease / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006615:Hip; D006801:Humans; D007231:Infant, Newborn; D007866:Leg; D008297:Male; D010243:Paralysis / Q000175:diagnosis / Q000209:etiology*; D010386:Pelvic Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D014750:Vincristine / Q000627:therapeutic use
D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide