Element mass spectrometry as a tool for high-resolution temporal dynamics investigations of peptide phosphorylation.
The great potential of capillary HPLC (capHPLC) coupled to element mass spectrometry (ICPMS) to study peptide phosphorylation dynamics was evaluated, and the high precision associated with the absolute quantification of the phosphopeptides provided the most detailed phosphorylation time profile ever reported.
Pereira Navaza
Ana
A
Department of Physical and Analytical Chemistry, University of Oviedo, Julian Claveria 8, 33006, Oviedo, Spain.
Ruiz Encinar
Jorge
J
Sanz-Medel
Alfredo
A
D002851:Chromatography, High Pressure Liquid; D013058:Mass Spectrometry / Q000379:methods*; D010455:Peptides / Q000032:analysis* / Q000737:chemistry*; D010766:Phosphorylation
D010455:Peptides