title: Efficacy of mineral cationic carrier against sulphur mustard in skin decontamination.
abstract: The aim of this study was to evaluate decontamination (absorption) efficacy of a preparation called Mineral Cationic Carrier (MCC) against skin contamination with sulphur mustard in vivo. MCC is a synthetic preparation with known ion exchange, absorption efficiency, and bioactive potential. CBA mice were applied increasing doses of sulphur mustard on their skin and MCC was administered immediately after skin contamination. The results have confirmed the decontamination efficacy of MCC preparation, corresponding to 8.4 times the LD50 of percutaneous sulphur mustard, and call for further investigation.
authors.affiliation: Institute of Researches and Development of Defense Systems, Zagreb, Croatia. ante.vucemilovic@inet.hr
authors.forename: Ante
authors.initials: A
authors.lastname: Vucemilović
authors.forename: Mirko
authors.initials: M
authors.lastname: Hadzija
authors.forename: Ivan
authors.initials: I
authors.lastname: Jukić
mesh_terms: D000818:Animals; D002619:Chemical Warfare Agents / Q000506:poisoning*; D003666:Decontamination; D007928:Lethal Dose 50; D051379:Mice; D008808:Mice, Inbred CBA; D009151:Mustard Gas / Q000506:poisoning*; D012867:Skin / Q000187:drug effects*
chemical_list: D002619:Chemical Warfare Agents; D009151:Mustard Gas