The prospects of glycan biomarkers for the diagnosis of diseases.
Over 40 years of literature shows that glycosylation is greatly affected by diseases such as cancer. This opinion article argues the intrinsic advantages of using glycans as disease markers over other biomolecules and the potential of glycan profiling for diagnosing and determining the progression of disease.
Lebrilla
Carlito B
CB
Department of Chemistry, University of California, Davis, USA. cblebrilla@ucdavis.edu
An
Hyun Joo
HJ
D015415:Biomarkers / Q000032:analysis; D003933:Diagnosis; D004194:Disease; D006801:Humans; D011134:Polysaccharides / Q000032:analysis / Q000378:metabolism*
D015415:Biomarkers; D011134:Polysaccharides