[Modification of impulse activity of cat brainstem monoaminergic cells caused by bemitil].
The study was carried out on brainstem noradrenergetic and serotoninergic neurons of cats and the effect of bemitil (100 mg/kg) introduction was investigated. The results indicate on specific bemitil action on scrotonin- and noradrenergetic neuromediator brain systems. Dose-dependency of the effect of bemitil is revealed.
Kolotilova
O I
OI
Koreniuk
I I
II
Fokina
Iu O
IuO
D000200:Action Potentials / Q000187:drug effects*; D000284:Administration, Oral; D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage / Q000494:pharmacology*; D015306:Biogenic Monoamines / Q000378:metabolism*; D001933:Brain Stem / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D002415:Cats; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism
D001562:Benzimidazoles; D015306:Biogenic Monoamines; D012701:Serotonin; C049825:bemethyl; D009638:Norepinephrine