Molecular imaging with bioconjugates in mouse models of cancer.
The definition of molecular imaging provided by the Society of Nuclear Medicine is "the visualization, characterization and measurement of biological processes at the molecular and cellular levels in humans and other living systems". This review gives an overview of the technologies available for and the potential benefits from molecular imaging at the preclinical stage. It focuses on the use of imaging probes based on bioconjugates and for reasons of brevity confines itself to discussion of applications in the field of oncology, although molecular imaging can be equally useful in many fields including cardiovascular medicine, neurosciences, infection, and others.
Mather
Stephen
S
Barts and The London Queen Mary's School of Medicine and Dentistry, Centre for Cancer Imaging Institute of Cancer and the CR-UK Clinical Centre, St. Bartholomew's Hos, United Kingdon. stephen.mather@cancer.org.uk
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D003287:Contrast Media / Q000737:chemistry; D003952:Diagnostic Imaging / Q000379:methods*; D004195:Disease Models, Animal; D055808:Drug Discovery; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism*
D015415:Biomarkers; D003287:Contrast Media