title: The role of manix in the management of idiopathic oligospermia. A pilot study at the Lagos University Teaching Hospital.
abstract: OBJECTIVE
  To assess the usefulness of Manix in the management of men with idiopathic oligospermia.
  
  
  METHODS
  The study involved 55 infertile men with idiopathic oligospermia. Thirty-five patients were administered oral 600 mg of manix for 13 weeks and 20 were put on oral 1000 IU of vitamin E for 13 weeks. Semen analysis and the sex hormone profiles were done as baseline and then repeated at 3 and 6 months.
  
  
  RESULTS
  There were statistically significant improvements in semen parameters in the patients on Manix . No improvement was noted in the other group on vit E. There was however no significant difference in pregnancy rates in the two groups.
  
  
  CONCLUSIONS
  Manix may play a role in the management of patients with idiopathic olligospermia. However, large scale double blind controlled trials are needed to confirm the findings in this preliminary study.
authors.affiliation: Urology unit, Dept of Surgery, College of Medicine, University of Lagos.
authors.forename: K H
authors.initials: KH
authors.lastname: Tijani
authors.forename: K
authors.initials: K
authors.lastname: Adegoke
authors.forename: A A
authors.initials: AA
authors.lastname: Oluwole
authors.forename: J
authors.initials: J
authors.lastname: Ogunlewe
mesh_terms: D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000097:blood / Q000188:drug therapy*; D008517:Phytotherapy / Q000379:methods*; D010865:Pilot Projects; D010936:Plant Extracts / Q000627:therapeutic use*; D012661:Semen / Q000187:drug effects; D016037:Single-Blind Method; D013739:Testosterone / Q000097:blood
chemical_list: D010936:Plant Extracts; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone