Anaphylaxis to husband's seminal plasma and treatment by local desensitization.
Hypersensitivity to human seminal fluid is rare but can be life threatening. We report a case of IgE-mediated anaphylaxis to seminal plasma that was diagnosed by skin prick tests and successfully treated by local desensitization. A 32-year-old woman suffering from angioedema and hypotension after exposure to semen was treated with epinephrine upon admission. Skin prick tests and immunoblotting for IgE binding components showed that she was sensitized to her husband's seminal plasma. Local desensitization, which persisted for six months, was achieved by intravaginal administration of serial dilutions of her husband's seminal plasma.
Lee
Jaechun
J
Department of Medicine, School of Medicine, Jeju National University, Jeju, Korea. doc4u@hanmail.net.
Kim
Sohyung
S
Kim
Miok
M
Chung
Young-Bae
YB
Huh
Jung-Sik
JS
Park
Chul Min
CM
Lee
Keun Hwa
KH
Kim
Jeong Hong
JH