Oral beclomethasone: a review of its use in inflammatory bowel disease.
Corticosteroids have represented the mainstay of medical treatment for induction of remission in inflammatory bowel disease. Aim of this paper is to review mechanisms of action, safety and efficacy of beclomethasone dipropionate, a steroid with enhanced topical intestinal activity and low systemic activity, in the treatment of inflammatory bowel disease.
Danese
Silvio
S
Division of Gastroenterology, Istituto Clinico Humanitas-IRCCS in Gastroenterology, Viale Manzoni, Rozzano, Milan, Italy. sdanese@hotmail.com
Angelucci
Erika
E
Marconi
Stefano
S
Repici
Alessandro
A
Malesci
Alberto
A
D000284:Administration, Oral; D001507:Beclomethasone / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D004361:Drug Tolerance; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*
D001507:Beclomethasone