title: Preliminary investigation on the phytochemistry and antimicrobial activity of Senna alata L. flower.
abstract: Preliminary studies on the phytochemistry and extracts of water, methanol, chloroform and petroleum ether, of Senna alata flowers were examined for antimicrobial properties. Extracts tested at a final concentration of 500 microg mL(-1) produced in vitro antimicrobial activities in assays against clinical isolates of Staphylococus aureus, Candida albicans, Escherichia coli, Proteus vulgaris, Pseudomonans aureginosa and Bacillus subtilis. The zones of inhibitions produced by the extracts in agar diffusion assay against the test micro organisms ranged from 4 to 10 mm while the gentamycin antibiotic control, produced zones that measured 5 mm. Preliminary phytochemical analysis of the plant extracts showed the presence of phenols, tannins, anthraquinoes, saponins, flavonoids.
authors.affiliation: Department of Botany, University of Benin, PMB 1154, Benin City, Nigeria.
authors.forename: M
authors.initials: M
authors.lastname: Idu
authors.forename: S E
authors.initials: SE
authors.lastname: Omonigho
authors.forename: C L
authors.initials: CL
authors.lastname: Igeleke
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000145:classification / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D007887:Fabaceae / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts