Rapidly progressive, acute polyradiculopathies and cranial neuropathies resulting from leptomeningeal nasal-type NK cell lymphoma.
Lymphomas may cause polyradiculopathies by several pathogenic mechanisms. However, such a presentation of a nasal-type NK (natural killer) cell lymphoma is rare. We report a previously healthy man who developed acute, axon-loss radiculopathies and cranial neuropathies. Despite the lack of a nasal or midline facial mass, cerebrospinal fluid cytologic and flow cytometric immurtophenotypic studies disclosed that the patient's rapid demise was the result of a nasal-type NK cell lymphoma with leptomeningeal involvement.
Zaretsky
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M
From the department of *Neurology,daggerNeurosurgery (Neuro-Oncology)and double daggerPathology, University of Piusburgh Piusburgh,PA.
Pulipaka
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U
Schiff
D
D
Bahler
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D
Lacomis
D
D