title: Disturbance of cerebral neuronal migration following congenital parvovirus B19 infection.
abstract: OBJECTIVE
  We describe the clinical course of an infant who presented with severe fetal anemia and fetal hydrops following congenital parvovirus B19 infection before 16 gestational weeks. The fetus was treated by cordocentesis and intrauterine transfusion at 18 weeks.
  
  
  RESULTS
  The infant demonstrated mild unilateral ventriculomegaly on antenatal magnetic resonance imaging, and polymicrogyria and heterotopia on postnatal magnetic resonance imaging.
  
  
  CONCLUSIONS
  This adds to the evidence in recent literature of central nervous system damage associated with congenital parvovirus B19 infection.
authors.affiliation: Department of Obstetrics, University Medical Center Utrecht, Utrecht, The Netherlands. l.pistorius@umcutrecht.nl
authors.forename: Lourens Rasmus
authors.initials: LR
authors.lastname: Pistorius
authors.forename: Jaime
authors.initials: J
authors.lastname: Smal
authors.forename: Timo Robert
authors.initials: TR
authors.lastname: de Haan
authors.forename: Godelieve C M L
authors.initials: GC
authors.lastname: Page-Christiaens
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Verboon-Maciolek
authors.forename: Dick
authors.initials: D
authors.lastname: Oepkes
authors.forename: Linda S
authors.initials: LS
authors.lastname: de Vries
mesh_terms: D000328:Adult; D001805:Blood Transfusion, Intrauterine; D001921:Brain / Q000002:abnormalities* / Q000821:virology; D001927:Brain Diseases / Q000151:congenital / Q000473:pathology / Q000821:virology*; D002465:Cell Movement; D002828:Choristoma / Q000151:congenital / Q000473:pathology / Q000821:virology*; D018792:Encephalitis, Viral / Q000150:complications* / Q000151:congenital / Q000473:pathology; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000628:therapy; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D010322:Parvoviridae Infections / Q000150:complications* / Q000151:congenital / Q000473:pathology; D016732:Parvovirus B19, Human; D011247:Pregnancy; D016216:Ultrasonography, Prenatal