Mismatch negativity in patients with (central) auditory processing disorders.
Mismatch Negativity (MMN) is a long-latency auditory evoked potential that provides an objective index of discrimination skills and auditory sensorial memory. It may, therefore, be used as an electrophysiological evaluation of central auditory processing.


OBJECTIVE
To study MMN in patients with Central Auditory Processing Disorder - CAPD.


METHODS
A prospective clinical study.


METHODS
Eight individuals with CAPD, aged between nine and 14 years, were evaluated; there was also a control group. MMN was elicited for tone stimuli (tone bursts), differing in terms of frequency (MMNf - standard stimulus: 750 Hz and deviant stimulus: 1,000 Hz ), as well as duration (MMNd - standard stimulus: 100 ms and deviant stimulus: 50 ms; at 1,000 Hz).


RESULTS
The presence of MMNf and of MMNd was statistically demonstrated in both groups. No significant statistical differences, however, were observed between MMNf and MMNd latencies and amplitude values in the two groups. Also, no significant statistical differences were observed between the MMNf and the MMNd among the groups.


CONCLUSIONS
The CAPD individuals that were evaluated showed no changes in MMNf or MMNd.
Roggia
Simone Mariotto
SM
Doctor, adjunct professor of the Speech Therapy course, UNIVALI - SC. Electronic address: simoneroggia@yahoo.com.br.
Colares
Nádia Tenório
NT
Student of Speech Therapy, UNIVALI - SC; science initiation scholarship. Universidade do Vale do Itajaí.
D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D001307:Auditory Perception / Q000502:physiology; D001308:Auditory Perceptual Disorders / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011930:Reaction Time