title: Versatile Pd(II)-catalyzed C-H activation/aryl-aryl coupling of benzoic and phenyl acetic acids.
abstract: The use of aryltrifluoroborates as coupling partners and O(2) as the oxidant substantially improves the scope and practicality of the Pd-catalyzed C-H activation/C-C coupling reaction. The newly discovered protocol made possible, for the first time, the ortho-coupling of electron-deficient arenes and phenyl acetic acids with organometallic reagents.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Dong-Hui
authors.initials: DH
authors.lastname: Wang
authors.forename: Tian-Sheng
authors.initials: TS
authors.lastname: Mei
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000138:chemical synthesis*; D001881:Borates / Q000737:chemistry; D002384:Catalysis; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D010648:Phenylacetates / Q000737:chemistry*
chemical_list: D001565:Benzoates; D001713:Biphenyl Compounds; D001881:Borates; D009942:Organometallic Compounds; D010648:Phenylacetates; D010165:Palladium; C025136:phenylacetic acid