title: Parturition in domestic animals: targets for future research.
abstract: Contents Compared with other parts of the reproductive cycle, the parturition process of domestic animals has received relatively little attention from researchers during the last two decades. Yet, interventions during parturition, either by the owner or the veterinarian, are frequently judged necessary and perinatal losses in most of the domestic species are (still) rather high. The present paper focuses on the birth process in three domestic species, the dog, pig and cow, mainly because most of the experimental and research work of the authors themselves was dealing with these three species. Against the background of specific clinical problems, breeding circumstances and economic performance, selected topics and questions are addressed to identify areas for future research. These are, among others, related to the mechanisms that trigger the birth process (are the foetuses involved in the dog and sow?), the role of hormones and cytokines during ripening of the cervix (activation and/or de-activation of specific matrix metallo-proteinases and their local inhibitors), the functional significance of fetal body movements to prepare the foetus for expulsion, and the exact time course of events involved in the transportation of an individual foetus from its intrauterine location, via the pelvic canal, to the outside world. Research on some of these topics, such as the ripening of the cervix in cows, might also contribute to resolve clinical problems in human obstetrics.
authors.affiliation: Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. m.a.m.taverne@uu.nl
authors.forename: M A M
authors.initials: MA
authors.lastname: Taverne
authors.forename: G C
authors.initials: GC
authors.lastname: van der Weijden
mesh_terms: D000818:Animals; D002417:Cattle / Q000502:physiology*; D020070:Cervical Ripening / Q000502:physiology*; D004285:Dogs / Q000502:physiology*; D005260:Female; D036801:Parturition / Q000502:physiology*; D011247:Pregnancy; D013045:Species Specificity; D013552:Swine / Q000502:physiology*; D013997:Time Factors