Von hippel-lindau disease associated with thymoma and myasthenia gravis.
Von Hippel-Lindau (VHL) disease is an autosomal-dominant disorder characterized by central nervous system hemangioblastomas, retinal angioma, and renal cell carcinoma. Thymoma and autoimmune neurologic disorders have not been reported in association with VHL disease. We report a unique concurrence of antibody-positive myasthenia gravis and thymoma in a patient with VHL disease. Although this may be coincidental, a possible genetic link between thymoma and VHL is described.
Sheth
Maushmi N
MN
From the Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX.
Nations
Sharon P
SP
Wolfe
Gil I
GI
Trivedi
Jaya R
JR