title: Phage display derived therapeutic antibodies.
abstract: This article gives an overview about the development of human therapeutic antibodies generated by phage display. After an introduction to the method, the focus is on approved antibodies and those currently in clinical trials, 14 of which are described in detail.
authors.affiliation: Technical University of Braunschweig, Institute of Biochemistry and Biotechnology, Spielmannstr. 7, 38106 Braunschweig, Germany.
authors.forename: Holger
authors.initials: H
authors.lastname: Thie
authors.forename: Torsten
authors.initials: T
authors.lastname: Meyer
authors.forename: Thomas
authors.initials: T
authors.lastname: Schirrmann
authors.forename: Michael
authors.initials: M
authors.lastname: Hust
authors.forename: Stefan
authors.initials: S
authors.lastname: Dübel
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D015195:Drug Design; D006801:Humans; D007167:Immunotherapy / Q000379:methods* / Q000639:trends*; D019151:Peptide Library; D015202:Protein Engineering / Q000639:trends*
chemical_list: D000911:Antibodies, Monoclonal; D019151:Peptide Library