Idiopathic polyhydramnios and postnatal findings.
OBJECTIVE
Our objective was to investigate the outcome of neonates with idiopathic polyhydramnios in the first year after birth.


METHODS
All patients diagnosed in the Erasmus Medical Centre Rotterdam and the University Medical Centre Utrecht between January 2000 and April 2005 with idiopathic polyhydramnios were studied. The outcome variables included mode of delivery, pre-term delivery, birth weight, macrosomia, large-for-gestational-age (weight > p90), neonatal or infant mortality and infant morbidity at 1 year after delivery. These were related to antenatal findings, including the onset of polyhydramnios and ultrasonographic evidence of macrosomia (estimated fetal weight > p90).


RESULTS
Polyhydramnios was diagnosed at a mean gestational age (+/- s.d.) of 31.0 +/- 4.9 weeks. The mean gestational age at birth (+/- s.d.) was 37.9 +/- 3.7 weeks. Macrosomia at birth was present in 25.3% (22/88). Sixty-three of 88 infants were in good health 1 year after birth; 20 infants had an abnormality and 5 children had died. Macrosomia and detection of polyhydramnios in the third trimester was associated significantly with a good outcome.


CONCLUSIONS
In neonates with idiopathic polyhydramnios, abnormalities were detected during the first year of life in 28.4%. Detection of polyhydramnios in the second trimester and low or normal birth weight are risk factors for associated abnormalities.
Dorleijn
Desirée M J
DM
Division of Perinatology and Gynecology, University Medical Centre Utrecht, Utrecht 3508 AB, The Netherlands.
Cohen-Overbeek
Titia E
TE
Groenendaal
Floris
F
Bruinse
Hein W
HW
Stoutenbeek
Philip
P
D000328:Adult; D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D006831:Polyhydramnios / Q000453:epidemiology*; D011247:Pregnancy