title: Efficient and divergent synthesis of cyclophosphamide analogues from 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans.
abstract: A facile and efficient one-pot synthesis of substituted cyclophosphamidic chlorides and their analogues has been developed from readily available enaminones, 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans.
authors.affiliation: Department of Chemistry, Northeast Normal University, 130024, Changchun, China.
authors.forename: Dexuan
authors.initials: D
authors.lastname: Xiang
authors.forename: Peng
authors.initials: P
authors.lastname: Huang
authors.forename: Kewei
authors.initials: K
authors.lastname: Wang
authors.forename: Guangyuan
authors.initials: G
authors.lastname: Zhou
authors.forename: Yongjiu
authors.initials: Y
authors.lastname: Liang
authors.forename: Dewen
authors.initials: D
authors.lastname: Dong
mesh_terms: D000107:Acetylation; D000588:Amines / Q000737:chemistry*; D003520:Cyclophosphamide / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D011714:Pyrans / Q000737:chemistry*
chemical_list: D000588:Amines; D011714:Pyrans; C030011:carbene; D006859:Hydrogen; D003520:Cyclophosphamide; D008697:Methane