Resin glycoside constituents of Ipomoea pes-caprae (beach morning glory).
Eight new resin glycosides, pescapreins X-XVII (1-8), were isolated from a lipophilic fraction of an ethanol extract of the entire plant of beach morning glory, Ipomoea pes-caprae. Their structures were elucidated by spectroscopic data analysis and by chemical transformation. These compounds were evaluated biologically in terms of cancer cell line cytotoxicity, antibacterial and antifungal activity, and effects on the mu-opioid receptor.
Tao
Hongwen
H
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
Hao
Xiaojiang
X
Liu
Jinggen
J
Ding
Jian
J
Fang
Yuchun
Y
Gu
Qianqun
Q
Zhu
Weiming
W
D000818:Animals; D002240:Carbohydrate Sequence; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005227:Fatty Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D027741:Ipomoea / Q000737:chemistry*; D007941:Leukemia P388; D051379:Mice; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D017450:Receptors, Opioid, mu / Q000187:drug effects; D012116:Resins, Plant / Q000737:chemistry / Q000302:isolation & purification*
D004365:Drugs, Chinese Herbal; D005227:Fatty Acids; D006027:Glycosides; D017450:Receptors, Opioid, mu; D012116:Resins, Plant