Thermal epimerization of diastereomeric Grignard reagents.
Thermal epimerization is the key to changing the endo-to-exo ratio of the diastereomeric bornyl and fenchyl Grignard reagents from 67:33 to 96:4 and from 20:80 to 80:20, respectively.
Beckmann
Jens
J
Institut für Chemie und Biochemie, Anorganische und Analytische Chemie, Freie Universität Berlin, Fabeckstr. 34-36, 14195, Berlin, Germany. beckmann@chemie.fu-berlin.de
Schütrumpf
Alexandra
A