[Influences of jiejiu gankang granule on lipid metabolism and liver function of alcohol-fatty-liver about mice].
OBJECTIVE
Jiejiu Gankang granule had been observed the effect on the model of the alcohol-fatty-liver about mice on lipid metabolism.


METHODS
There was the model of alcohol-fatty-liver adopted in this experiment. The effect had been observed of Jiejiu Gankang granule in different dosages on blood-lipoid metabolism, intrahepatic-lipoid metabolism, energy metabolism or and oxidative damage degree.


RESULTS
Jiejiu Gankang granule can decrease the level of TG, LDL, MDA in blood obviously. It can decrease the content of Gn, MDA and improve the level of SOD in liver obviously.


CONCLUSIONS
There was some reference of dosage dependence on the intensity of potency action in high, middle and low dosage of this drug.
Li
Bin
B
Shandong Academy of Chinese Medicine, Jinan 250014, China.
Wang
Li
L
Sun
Rong
R
D000818:Animals; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005235:Fatty Liver, Alcoholic / Q000378:metabolism* / Q000473:pathology; D050356:Lipid Metabolism / Q000187:drug effects*; D008077:Lipoproteins, LDL / Q000097:blood; D008099:Liver / Q000187:drug effects* / Q000378:metabolism* / Q000473:pathology; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D051379:Mice; D011897:Random Allocation; D013482:Superoxide Dismutase / Q000378:metabolism; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D008077:Lipoproteins, LDL; D014280:Triglycerides; D008315:Malondialdehyde; D013482:Superoxide Dismutase