title: Increase of frequency in deep brain stimulation relieves apraxia of eyelid opening in patients with Parkinson's disease: case report.
abstract: OBJECTIVE
  Deep brain stimulation (DBS) of the subthalamic nucleus is an effective treatment in advanced stages of Parkinson's disease. However, approximately 5% of patients might develop apraxia of eyelid opening after DBS of the subthalamic nucleus. We provide data on a new noninvasive treatment approach to this adverse event.
  
  
  METHODS
  We report 2 patients who acquired apraxia of eyelid opening after DBS. This adverse event was relieved by changing the stimulation parameters.
  
  
  METHODS
  The stimulation frequency was increased from 100 Hz to 180 Hz in 1 patient and 160 Hz in the other, resulting in a total relief of symptoms.
  
  
  CONCLUSIONS
  Increasing stimulation frequency may be beneficial in apraxia of eyelid opening acquired after DBS of the subthalamic nucleus.
authors.affiliation: Department of Neurology, University of Leipzig, Leipzig, Germany. KarlStrecker@gmx.de
authors.forename: Karl
authors.initials: K
authors.lastname: Strecker
authors.forename: Jürgen
authors.initials: J
authors.lastname: Meixensberger
authors.forename: Johannes
authors.initials: J
authors.lastname: Schwarz
authors.forename: Dirk
authors.initials: D
authors.lastname: Winkler
mesh_terms: D000368:Aged; D001072:Apraxias / Q000175:diagnosis* / Q000209:etiology / Q000534:rehabilitation*; D046690:Deep Brain Stimulation / Q000379:methods*; D005141:Eyelid Diseases / Q000175:diagnosis* / Q000209:etiology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis* / Q000534:rehabilitation*