Phage display derived therapeutic antibodies.
This article gives an overview about the development of human therapeutic antibodies generated by phage display. After an introduction to the method, the focus is on approved antibodies and those currently in clinical trials, 14 of which are described in detail.
Thie
Holger
H
Technical University of Braunschweig, Institute of Biochemistry and Biotechnology, Spielmannstr. 7, 38106 Braunschweig, Germany.
Meyer
Torsten
T
Schirrmann
Thomas
T
Hust
Michael
M
Dübel
Stefan
S
D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D015195:Drug Design; D006801:Humans; D007167:Immunotherapy / Q000379:methods* / Q000639:trends*; D019151:Peptide Library; D015202:Protein Engineering / Q000639:trends*
D000911:Antibodies, Monoclonal; D019151:Peptide Library