Fast capillary electrophoresis coupled with time-of-flight mass spectrometry under separation conditions of high electrical field strengths.
An experimental approach is presented that enables very fast capillary electrophoretic separations in conjunction with time-of-flight mass spectrometry. Field strengths exceeding 1 kV cm(-1) have been applied for separations of model analytes resulting in migration times on the timescale of seconds.
Matysik
Frank-Michael
FM
Institute of Analytical Chemistry, University of Regensburg, Regensburg, Germany. frank-michael.matysik@chemie.uni-regensburg.de
Neusüss
Christian
C
Pelzing
Matthias
M
D000818:Animals; D019075:Electrophoresis, Capillary / Q000379:methods*; D017022:Flow Injection Analysis / Q000379:methods; D006639:Histidine / Q000032:analysis; D006801:Humans; D008687:Metformin / Q000032:analysis; D012710:Serum Albumin, Bovine / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D012710:Serum Albumin, Bovine; D006639:Histidine; D008687:Metformin