[Effect of calcitonin on articular cartilage of osteoarthritis].
OBJECTIVE
To review the effect of calcitonin on cartilage and subchondral bone of osteoarthritis.


METHODS
Recent literatures about the effect of calcitonin on osteoarthritis was reviewed.


RESULTS
Calcitonin could promote the synthesis of important cartilage matrix such as proteoglycans and collagen II, propelling the regeneration of cartilage and subchondral bone.


CONCLUSIONS
Calcitonin can protect articular cartilage through promoting the synthesis of cartilage and inhibiting its degradation.
Zhang
Yinna
Y
Department of Pathology, Affiliated Hospital, North China Coal Medical College, Tangshan Hebei 063000, PR China.
Wang
Wenya
W
Zhang
Liu
L
D002116:Calcitonin / Q000494:pharmacology*; D002358:Cartilage, Articular / Q000187:drug effects* / Q000378:metabolism; D010003:Osteoarthritis / Q000378:metabolism
D002116:Calcitonin