[Primary systemic amyloidosis with exclusive involvement of the tongue as an exceptional cause of dysphagia].
We present a 73-year-old woman with progressive dysphagia and dysarthria over two years associated with systemic symptoms including weight loss, asthenia and dyspnoea. Biopsy of the tongue demonstrated amyloid AL deposits. The immunohistochemical study showed a notable positiveness to antibodies for L-kappa chains. The patient died 6 months after diagnosis.
Mera Menéndez
Fernando
F
Servicio de Otorrinolaringología, Hospital Universitario de La Princesa, Madrid, España. fermera@yahoo.com
Alvarez Carrillo
Solssiree
S
Hinojar Gutiérrez
Adolfo
A
Nieto
Santiago
S
Raboso García-Baquero
Eduardo
E
D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology*; D003680:Deglutition Disorders / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D014060:Tongue Diseases / Q000473:pathology*