Genetic polymorphisms of 16 Y chromosomal STR loci in Korean population.
Allele frequencies and haplotypes of 16 Y chromosomal STR loci included in the AmpFlSTR((R)) Yfilertrade mark system were obtained from a sample of 526 unrelated Korean male individuals. A total of 478 haplotypes were observed in the 526 individuals studied, of which 440 were unique. The overall haplotype diversity for the 16 Y-STR loci was 0.9996, and the discrimination capacity was 0.9087. We found 13 atypical alleles, including null, duplicated and microvariant alleles. Microvariants have been characterized by sequencing, 14.1 allele at DYS458 showing the flanking site mutation, 13.1 and 15.2 allele at DYS385a/b showing changes in the repeat structure.
Kim
Soon Hee
SH
DNA Analysis Division, National Institute of Scientific Investigation, Seoul, Republic of Korea.
Kim
Nam Ye
NY
Hong
Seung Beom
SB
Cho
Nam Soo
NS
Kim
Jong Jin
JJ
Han
Myun Soo
MS
Kim
Won
W
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D041322:Chromosomes, Human, Y; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D016172:DNA Fingerprinting / Q000379:methods; D005787:Gene Frequency; D005819:Genetic Markers; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D007723:Korea; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D021141:Nucleic Acid Amplification Techniques; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D044382:Population Groups / Q000235:genetics*; D011786:Quality Control
D005819:Genetic Markers; D004247:DNA