title: Determination of atenolol at a graphite-polyurethane composite electrode.
abstract: A bare graphite-polyurethane composite was evaluated as an alternative electrode in the determination of atenolol (ATN) in pharmaceutical formulations. Using a DPV procedure, a linear analytical curve was observed in the 4-100mumolL(-1) range with a LOD=3.16mumolL(-1), without need of surface renewing between successive runs, with recoveries between 95.5 and 108%. Interference of other antihypertensive drugs was observed, but not from the usual components of tablets. The results of the proposed method agreed with HPLC ones within 95% confidence level.
authors.affiliation: Universidade de Sao Paulo, Instituto de Quimica de Sao Carlos, Av. do Trabalhador Sancarlense, 400, 13566-590 Sao Carlos, SP, Brazil.
authors.forename: Priscila
authors.initials: P
authors.lastname: Cervini
authors.forename: Luiz Antônio
authors.initials: LA
authors.lastname: Ramos
authors.forename: Eder Tadeu Gomes
authors.initials: ET
authors.lastname: Cavalheiro