Therapeutic drug monitoring of voriconazole in a child with invasive aspergillosis requiring extracorporeal membrane oxygenation.
We describe a patient with invasive pulmonary aspergillosis on extracorporeal membrane oxygenation therapy in which therapeutic drug monitoring and individualization of therapy by measuring voriconazole plasma concentrations were performed.
Brüggemann
Roger J M
RJ
Department of Clinical Pharmacy, Nijmegen University Centre for Infectious Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. r.bruggemann@akf.umcn.nl
Antonius
Tim
T
Heijst
Arno van
Av
Hoogerbrugge
Peter M
PM
Burger
David M
DM
Warris
Adilia
A
D000935:Antifungal Agents / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy*; D002675:Child, Preschool; D016903:Drug Monitoring; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D008297:Male; D011743:Pyrimidines / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D014230:Triazoles / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole