title: Health-related quality of life after prolonged pediatric intensive care unit stay.
abstract: OBJECTIVE
  To investigate the long-term health-related quality of life (HRQOL) outcomes for patients requiring at least 28 days of pediatric intensive care.
  
  
  METHODS
  Retrospective cohort and prospective follow-up study.
  
  
  METHODS
  A 21-bed pediatric intensive care unit (PICU) in a university-affiliated, tertiary referral pediatric hospital.
  
  
  METHODS
  One hundred ninety-three patients who spent 28 days or longer in the PICU between January 1, 1997 and December 31, 2004.
  
  
  METHODS
  Quality of life was measured using the Pediatric Quality of Life Inventory (Peds QL 4.0) parent-proxy version at 2 to 10 yrs after discharge. The PedsQL 4.0 is a modular measure of HRQOL, which is reliable in children aged 2 to 18 yrs. It generates a total score and physical, emotional, social, school, and psychosocial subscores.
  
  
  RESULTS
  Of the 193 patients, 41 died during their PICU admission and 27 died between PICU discharge and follow-up. Quality of life questionnaires were posted to parents of 108 of the 125 survivors and 70 were returned completed. Forty children (57.1%) had scores indicating a normal quality of life, whereas 30 (42.9%) had scores indicating impaired HRQOL. Of these, 14 (20%) had scores indicating poor quality of life with ongoing disabling health problems requiring hospitalization or the equivalent.
  
  
  CONCLUSIONS
  Our results indicate that, while long PICU stay is associated with significant mortality, the long-term HRQOL is normal for the majority of surviving children.
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Our Lady's Hospital for Sick Children, Crumlin Road, Crumlin, Dublin, Ireland.
authors.forename: Niamh P
authors.initials: NP
authors.lastname: Conlon
authors.forename: Cormac
authors.initials: C
authors.lastname: Breatnach
authors.forename: Brendan P
authors.initials: BP
authors.lastname: O'Hare
authors.forename: David W
authors.initials: DW
authors.lastname: Mannion
authors.forename: Barry J
authors.initials: BJ
authors.lastname: Lyons
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003266:Continuity of Patient Care / Q000706:statistics & numerical data; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D015278:Intensive Care Units, Pediatric; D007494:Ireland; D007902:Length of Stay; D008134:Long-Term Care; D008297:Male; D010351:Patient Discharge; D011336:Probability; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D018709:Statistics, Nonparametric; D013997:Time Factors