Protein-losing enteropathy in a case of nodal follicular lymphoma without a gastrointestinal mucosal lesion.
Protein-losing enteropathy (PLE) is characterized by gastrointestinal loss of serum protein. It is usually caused by hypersecretion from a tumor, ulcer, or long standing lymphangiectasia. However, we report a 47-year-old man of peritoneal nodal follicular lymphoma who developed PLE with none of them. Oozing of whitish fluid from duodenal bulbar mucosa was endoscopically seen, resulting in continuous loss of protein. Chemotherapy was effective and PLE was rapidly diminished. Nodal lymphoma lesion was considered to disturb lymphatic flow and to regurgitate it to duodenal mucosa. To our knowledge, this is the second report of a lymphoma patient presenting PLE without a gastrointestinal mucosal lesion.
Kaneko
Hiroto
H
Department of Hematology, Aiseikai-Yamashina Hospital, Kyoto. hp@aiseikaihp.or.jp
Yamashita
Mihoko
M
Ohshiro
Muneo
M
Ohkawara
Yasuo
Y
Matsumoto
Yosuke
Y
Nomura
Kenichi
K
Horiike
Shigeo
S
Yokota
Shouhei
S
Taniwaki
Masafumi
M
D005753:Gastric Mucosa / Q000473:pathology*; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008224:Lymphoma, Follicular / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011504:Protein-Losing Enteropathies / Q000150:complications / Q000175:diagnosis* / Q000473:pathology