title: Rectal cancer.
abstract: Rectal cancer is an important tumour from an epidemiological point of view and represents the benchmark for an optimal use of integrated treatments (surgery, radiotherapy and chemotherapy) in the oncological practice. The conventional use of total mesorectal excision and the integration with radiochemotherapy, better if preoperatively, are now able to increase survival, to decrease the occurrence of pelvic recurrence and to ameliorate the quality of life of patients. Updated recommendations for the management of these patients are here reported.
authors.affiliation: Medical Care Unit, European Institute of Oncology, Milan, Italy. maria.zampino@ieo.it
authors.forename: Maria Giulia
authors.initials: MG
authors.lastname: Zampino
authors.forename: Roberto
authors.initials: R
authors.lastname: Labianca
authors.forename: Giordano D
authors.initials: GD
authors.lastname: Beretta
authors.forename: Elena
authors.initials: E
authors.lastname: Magni
authors.forename: Gemma
authors.initials: G
authors.lastname: Gatta
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Leonardi
authors.forename: Antonio
authors.initials: A
authors.lastname: Chiappa
authors.forename: Roberto
authors.initials: R
authors.lastname: Biffi
authors.forename: Filippo
authors.initials: F
authors.lastname: de Braud
authors.forename: Jacques
authors.initials: J
authors.lastname: Wils
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D015994:Incidence; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents