Surgical treatment of patients with the complicated clinical course of gastric cancer.
Research objective was to study the results of surgical treatment of gastric cancer with clinical diseases complicated by the concomitant pathology in patients of different age groups. The author analysed data on 98 patients men and women with gastric cancer who received surgical treatment in the Abdominal Oncology Department at the National Centre of Oncology (Azerbaijan Republic) in 2004-2007. Four patients with gastric cancer were under 40 years old; twenty patients were from 41 to 50 years old; twenty five patients were from 51 to 60 years old; forty three patients were from 61 to 70 years old; six patients were older than 70. Clinical stages of the malignant process were defined according to TNM classification. In 7 of 98 patients with gastric cancer, clinical stage I of the disease was determined. In 26 of 98 patients clinical stage II was determined. In 51 patients clinical stage III was determined. In 14 patients clinical stage IV was determined. 67 of 98 patients had complication of the disease. Prognostic value of cellular immunity in gastric cancer was determined. More than 80% patients with gastric cancer had increased levels of Cancer Embryonic Antigen in the blood serum. The data analysis of long-term treatment of patients with gastric cancer showed 16.7% recurrence rate and 22.8% metastasis rate in under 50 year old patients, 10.4% recurrence rate and 11.9% metastasis rate in 51-70 year old patients, 0% recurrence rate and 20% metastasis rate in 70 year old patients. Multivariate analysis revealed the factors for determining the gastric cancer prognosis. Detection of the tumor in an early stage, standardized surgical treatment, close follow-up schedules and better perioperative management are expected to increase survival time for patients with gastric cancer.
Aliyev
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The National Centre of Oncology, Baku, Azerbaijan Republic.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D016896:Treatment Outcome