Role of nitric oxide in physiology and pathology of the gastrointestinal tract.
In this paper the physiological role of NO and isoforms of NOS in the gastrointestinal tract and the involvement of NO in pathological processes of digestive tract as well as the perspective of therapeutic use of NO-donating drugs and selective inhibitors of phosphodiesterase in the treatment of gastric diseases were presented.
Stanek
A
A
Department of Internal Diseases, Angiology and Physical Medicine, Medical University of Silesia, Batorego St. 15, PL-41902 Bytom, Poland. agatastanek@mediclub.pl
Gadowska-Cicha
A
A
Gawron
K
K
Wielkoszyński
T
T
Adamek
B
B
Cieślar
G
G
Wiczkowski
A
A
Sieroń
A
A
D000818:Animals; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D041981:Gastrointestinal Tract / Q000378:metabolism / Q000473:pathology / Q000502:physiology* / Q000503:physiopathology*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000502:physiology; D009569:Nitric Oxide / Q000737:chemistry / Q000378:metabolism*; D020030:Nitric Oxide Donors / Q000378:metabolism / Q000627:therapeutic use; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism; D013272:Stomach Diseases / Q000188:drug therapy / Q000473:pathology* / Q000503:physiopathology*
D004791:Enzyme Inhibitors; D007527:Isoenzymes; D020030:Nitric Oxide Donors; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase