Categorization of Skindex-29 scores using mixture analysis.
BACKGROUND
Although the Skindex-29 is among the most commonly used health-related quality of life instruments in dermatology, the interpretation of obtained scores is not well documented.


OBJECTIVE
To create categories of the scores of the Skindex-29.


METHODS
The Skindex-29 scores of454 Italian patients with 6 distinct skin diseases from a specialized center were analyzed using mixture analyses. The validity of the obtained categorizations was tested.


RESULTS
Mixture analysis showed 4 distinct components (categories) for the emotion and functioning scale and 5 for the symptom scale. The total Skindex-29 score was categorized into 4 levels. As expected, patients with inflammatory diseases had higher levels of impairment, those with vitiligo and alopecia areata had low symptom levels and those with nevi were predominantly located in the lower categories for each of the scales.


CONCLUSIONS
The proposed categories of the Skindex-29 may ease the interpretation of obtained continuous scores.
Nijsten
Tamar
T
Department of Dermatology, Erasmus MC, Rotterdam, The Netherlands.
Sampogna
Francesca
F
Abeni
Damiano
D
D000152:Acne Vulgaris / Q000523:psychology; D000506:Alopecia Areata / Q000523:psychology; D012628:Dermatitis, Seborrheic / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009506:Nevus / Q000523:psychology; D011565:Psoriasis / Q000523:psychology; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D015203:Reproducibility of Results; D012871:Skin Diseases / Q000523:psychology*; D011795:Surveys and Questionnaires; D014820:Vitiligo / Q000523:psychology