Contributions of the basal ganglia and functionally related brain structures to motor learning.
This review discusses the cerebral plasticity, and the role of the cortico-striatal system in particular, observed as one is learning or planning to execute a newly learned motor behavior up to when the skill is consolidated or has become highly automatized. A special emphasis is given to imaging work describing the neural substrate mediating motor sequence learning and motor adaptation paradigms. These results are then put into a plausible neurobiological model of motor skill learning, which proposes an integrated view of the brain plasticity mediating this form of memory at different stages of the acquisition process.
Doyon
Julien
J
Functional NeuroImaging Unit, University of Montreal Geriatric Institute, Montreal, Quebec, Canada. julien.doyon@umontreal.ca
Bellec
Pierre
P
Amsel
Rhonda
R
Penhune
Virginia
V
Monchi
Oury
O
Carrier
Julie
J
Lehéricy
Stéphane
S
Benali
Habib
H
D000223:Adaptation, Psychological / Q000502:physiology*; D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology* / Q000502:physiology*; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D008568:Memory / Q000502:physiology*; D009048:Motor Skills / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*