title: An ionic liquid-type carbon paste electrode for electrochemical investigation and determination of calcium dobesilate.
abstract: An ionic liquid-type carbon paste electrode (IL-CPE) had been fabricated by replacing non-conductive organic binders with a conductive room temperature ionic liquid, 1-pentyl-3-methylimidazolium hexafluorophosphate (PMIMPF(6)). The electrochemical responses of calcium dobesilate were investigated at the IL-CPE and the traditional carbon paste electrode (T-CPE) in 0.05molL(-1) H(2)SO(4), respectively. The results showed the superiority of IL-CPE to T-CPE in terms of provision of higher sensitivity, faster electron transfer and better reversibility. A novel method for determination of calcium dobesilate was proposed. The oxidation peak current was rectilinear with calcium dobesilate concentration in the range of 8.0x10(-7) to 1.0x10(-4)molL(-1), with a detection limit of 4.0x10(-7)molL(-1) (S/N=3) by differential pulse voltammetry. The proposed method was applied to directly determine calcium dobesilate in capsule and urine samples.
authors.affiliation: Institute of Analytical Science, Shaanxi Provincial Key Lab of Electroanalytical Chemistry, Northwest University, Xi'an, Shaanxi 710069, China.
authors.forename: Jianbin
authors.initials: J
authors.lastname: Zheng
authors.forename: Ya
authors.initials: Y
authors.lastname: Zhang
authors.forename: Pingping
authors.initials: P
authors.lastname: Yang