title: Radiofrequency catheter ablation of idiopathic ventricular tachycardia and symptomatic premature ventricular contraction originating from valve annulus.
abstract: BACKGROUND
  Radiofrequency catheter ablation (RFCA) has been established as an effective and curative therapy for ventricular tachycardia (VT) and severely symptomatic premature ventricular contraction (PVC) from the outflow tract in structurally normal hearts. This study aimed to investigate electrophysiologic characteristics and effects of RFCA for patients with idiopathic VT and symptomatic PVC originating from the valve annulus.
  
  
  METHODS
  Characteristics of body surface electrocardiogram (ECG) and endocardiogram in a successful RFCA target were analyzed in 16 patients with idiopathic VT and symptomatic PVC originating from the valve annulus. Additionally, the ECG characteristics of VT or PVC were compared with those of manifest Wolff-Parkinson-White (WPW) syndrome originating from the same site of origin in 15 patients.
  
  
  RESULTS
  Thirteen patients were successful, 2 recurrent and 1 failed. The recurrent cases underwent successful ablation the second time guided by the Ensite 3000 mapping system. In all patients with the WPW syndrome, the characteristics of QRS morphology were well matched with those of the VT and PVC that originated from corresponding sites of origin.
  
  
  CONCLUSIONS
  RFCA is an effective curative therapy for VT and symptomatic PVC originating from the valve annulus. There are specific characteristics in ECG and the ablation site could be located by means of the WPW syndrome accessory pathway's algorithm.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China.
authors.forename: Xiao-yu
authors.initials: XY
authors.lastname: Wu
authors.forename: Zhao-guang
authors.initials: ZG
authors.lastname: Liang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Tan
authors.forename: Hong-yue
authors.initials: HY
authors.lastname: Gu
authors.forename: Shu
authors.initials: S
authors.lastname: Zhang
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D017115:Catheter Ablation / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology / Q000601:surgery; D017180:Tachycardia, Ventricular / Q000503:physiopathology* / Q000601:surgery; D018879:Ventricular Premature Complexes / Q000503:physiopathology* / Q000601:surgery