title: Developmental patterning by mechanical signals in Arabidopsis.
abstract: A central question in developmental biology is whether and how mechanical forces serve as cues for cellular behavior and thereby regulate morphogenesis. We found that morphogenesis at the Arabidopsis shoot apex depends on the microtubule cytoskeleton, which in turn is regulated by mechanical stress. A combination of experiments and modeling shows that a feedback loop encompassing tissue morphology, stress patterns, and microtubule-mediated cellular properties is sufficient to account for the coordinated patterns of microtubule arrays observed in epidermal cells, as well as for patterns of apical morphogenesis.
authors.affiliation: INRA, Laboratoire de Reproduction et Développement des Plantes, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Hamant
authors.forename: Marcus G
authors.initials: MG
authors.lastname: Heisler
authors.forename: Henrik
authors.initials: H
authors.lastname: Jönsson
authors.forename: Pawel
authors.initials: P
authors.lastname: Krupinski
authors.forename: Magalie
authors.initials: M
authors.lastname: Uyttewaal
authors.forename: Plamen
authors.initials: P
authors.lastname: Bokov
authors.forename: Francis
authors.initials: F
authors.lastname: Corson
authors.forename: Patrik
authors.initials: P
authors.lastname: Sahlin
authors.forename: Arezki
authors.initials: A
authors.lastname: Boudaoud
authors.forename: Elliot M
authors.initials: EM
authors.lastname: Meyerowitz
authors.forename: Yves
authors.initials: Y
authors.lastname: Couder
authors.forename: Jan
authors.initials: J
authors.lastname: Traas
mesh_terms: D017360:Arabidopsis / Q000033:anatomy & histology / Q000166:cytology / Q000254:growth & development*; D048430:Cell Shape; D002473:Cell Wall / Q000502:physiology / Q000648:ultrastructure; D002482:Cellulose; D004136:Dinitrobenzenes / Q000494:pharmacology; D018519:Meristem / Q000166:cytology / Q000254:growth & development*; D020894:Microfibrils / Q000502:physiology; D008870:Microtubules / Q000502:physiology* / Q000648:ultrastructure; D008954:Models, Biological; D009024:Morphogenesis; D019441:Plant Epidermis / Q000502:physiology; D018520:Plant Shoots / Q000033:anatomy & histology / Q000166:cytology / Q000254:growth & development*; D018547:Plant Stems / Q000166:cytology / Q000254:growth & development; D011312:Pressure; D013314:Stress, Mechanical; D013424:Sulfanilamides / Q000494:pharmacology; D050257:Tubulin Modulators / Q000494:pharmacology
chemical_list: D004136:Dinitrobenzenes; D013424:Sulfanilamides; D050257:Tubulin Modulators; C012465:oryzalin; D002482:Cellulose