[Structure and function of fungal cell wall].
Cell wall glycans of fungi/yeasts are reviewed. Fungi/yeasts produce various kinds of polysaccharides. As part of the cell wall they are interlinked with other components forming a huge network. The insolubility and complex with multiple components makes the research very tough. Studies on beta-glucan have been performed from various views, such as chemistry, conformation, solubility, tissue distribution and metabolism, biological activity, clinical application, receptor, biosynthesis, and antibody. Studies on mannan focus on immunotoxicity, such as anaphylactoid reaction and coronary arteritis induction. alpha-glucan, chitin, and capsular polysaccharide were also mentioned in relation to structure and genes. Compared with human and animal polysaccharides, fungi/yeasts polysaccharides have very characteristic properties.
Ohno
Naohito
N
Tokyo University of Pharmacy and Life Sciences.
D000707:Anaphylaxis / Q000209:etiology; D000818:Animals; D001167:Arteritis / Q000209:etiology; D002473:Cell Wall / Q000737:chemistry* / Q000502:physiology*; D003331:Coronary Vessels; D005658:Fungi / Q000166:cytology* / Q000378:metabolism; D006801:Humans; D008351:Mannans / Q000737:chemistry / Q000633:toxicity; D047071:beta-Glucans
D008351:Mannans; D047071:beta-Glucans