Diltiazem in the treatment of calcinosis in juvenile dermatomyositis.
Subcutaneous calcifications occur in a variety of diseases, including juvenile dermatomyositis. These calcifications cause disabling symptoms that do not always respond to immunosuppressant therapy. The calcium antagonist diltiazem reduces subcutaneous calcifications in CREST syndrome and in isolated cases of children with dermatomyositis. Our study was performed to determine the effects of diltiazem when used as adjunctive therapy in children with dermatomyositis.
Bertorini
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From the Departments of Neurology, daggerRadiology, double daggerMedicine, and section signPediatrics, The University of Tennessce Memphis, paragraph signMethodist Hospitals of Memphis, and paragraph signThe Memphis Neurosciences Center, Memphis, Tennessee.
Sebes
J I
JI
Palmieri
G M
GM
Igarashi
M
M
Horner
L H
LH