Immunity to Trichinella spiralis muscle infection.
Trichinella spiralis larvae establish chronic infections in skeletal muscles of immunocompetent hosts. Muscle infection is crucial to transmission and survival of the parasite in nature. Chronic infections by this highly immunogenic parasite are associated with modulation or escape from potentially destructive immune responses. This review summarizes our current knowledge of immunity to muscle infection with T. spiralis.
Fabre
M V
MV
James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Beiting
D P
DP
Bliss
S K
SK
Appleton
J A
JA
D000818:Animals; D051379:Mice; D018482:Muscle, Skeletal / Q000276:immunology* / Q000469:parasitology*; D017160:Trichinella spiralis / Q000276:immunology*; D014235:Trichinellosis / Q000276:immunology*