title: [Screening for systemic manifestations of vascular malformations in patients with hereditary haemorrhagic telangiectasia (Osler disease)].
abstract: Hereditary haemorrhagic telangiectasia (Rendu-Osler- Weber syndrome) is a disease characterized by systemic vascular malformations. Typical clinical manifestations are recurrent epistaxis and telangiectases of the skin and the mucous membranes. The syndrome is furthermore characterized by its hereditary aspect. The disease seems to be much more complicated than previously thought, mainly because of the accompanying vascular malformations in vital organs, like the liver, the kidney, the lung, the brain, and the eyes. The diagnosis and treatment of systemic vascular malformations requires interdisciplinary management.
authors.affiliation: Clínica de Otorrinolaringología, Klinikum der Philipp-Universität Marburg, Marburg, Alemania.
authors.forename: Ana
authors.initials: A
authors.lastname: Cerra Pohl
authors.forename: Jochen Alfred
authors.initials: JA
authors.lastname: Werner
authors.forename: Benedikt Josef
authors.initials: BJ
authors.lastname: Folz
mesh_terms: D001921:Brain / Q000098:blood supply; D002889:Chromosomes, Human, Pair 2 / Q000235:genetics; D005123:Eye / Q000098:blood supply; D006801:Humans; D007668:Kidney / Q000098:blood supply; D008099:Liver / Q000098:blood supply; D008168:Lung / Q000098:blood supply; D008403:Mass Screening / Q000379:methods*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000453:epidemiology* / Q000235:genetics / Q000503:physiopathology*; D054079:Vascular Malformations / Q000453:epidemiology* / Q000235:genetics / Q000503:physiopathology*