Mycotic encephalitis and nephritis in a dog due to infection with Cladosporium cladosporioides.
The dematiaceous fungus Cladosporium cladosporioides is a widely distributed saprophyte that is reported to occasionally infect the lung, skin, eye and brain of humans. This report describes a German shepherd dog with granulomatous encephalitis and nephritis due to C. cladosporioides infection. Although the fungal organisms appeared non-pigmented in haematoxylin and eosin stained sections, they were readily identified with histochemical stains. Semi-nested polymerase chain reaction using universal fungal primers amplified fungal DNA from fixed tissue that had identity to that of C. cladosporioides on sequencing.
Poutahidis
T
T
Laboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Veterinary Med. Bldg, AUTH Main Campus, 54124 Thessaloniki, Greece. teoput@vet.auth.gr
Angelopoulou
K
K
Karamanavi
E
E
Polizopoulou
Z S
ZS
Doulberis
M
M
Latsari
M
M
Kaldrymidou
E
E
D000818:Animals; D020314:Central Nervous System Fungal Infections / Q000150:complications / Q000662:veterinary*; D002540:Cerebral Cortex / Q000382:microbiology / Q000473:pathology; D002963:Cladosporium / Q000235:genetics / Q000472:pathogenicity*; D004271:DNA, Fungal / Q000378:metabolism; D004283:Dog Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D004285:Dogs; D004660:Encephalitis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D007678:Kidney Glomerulus / Q000382:microbiology / Q000473:pathology; D009393:Nephritis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*
D004271:DNA, Fungal