title: Helicobacter pylori and cagA seroprevalence in sub-Saharan inmigrants recently arrived to Gran Canaria (Spain).
abstract: Non-ulcerous dyspepsia is common among sub-Saharan people migrating into Spain. Given the high prevalence of H. pylori (HP) infection in their countries of origin, we studied the prevalence of infection in this population, and specifically the prevalence of infection by the more virulent, cagA-positive strains (CAP). 140 sub-Saharan immigrants recently arrived to Gran Canaria (Canary Islands, Spain) were studied. 80.7% were male, with a mean age of 24.2 y. 90.7% tested seropositive for HP and 72.2% of them carried antibodies against the 'pathogenicity island' cagA. We did not find any relationship between the presence of these antibodies and the clinical variables studied. We can conclude that HP infection is virtually universal in this population, with a high percentage of infection by CAP strains.
authors.affiliation: Sevicio de Medicina Interna, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Sanz-Peláez
authors.forename: Evora
authors.initials: E
authors.lastname: Santana-Rodríguez
authors.forename: Alfonso Angel-Moreno
authors.initials: AA
authors.lastname: Maroto
authors.forename: Cristina
authors.initials: C
authors.lastname: Carranza-Rodríguez
authors.forename: Elena
authors.initials: E
authors.lastname: Pisos-Alamo
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Pérez-Arellano
mesh_terms: D000328:Adult; D017954:Africa South of the Sahara; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology* / Q000378:metabolism; D001426:Bacterial Proteins / Q000276:immunology* / Q000378:metabolism; D054242:Emigrants and Immigrants; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D016480:Helicobacter pylori / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D008297:Male; D016036:Seroepidemiologic Studies; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C080866:cagA protein, Helicobacter pylori