title: Presence of asthma with night-time asthma symptoms is associated with impaired health-related quality of life in children.
abstract: Few studies have compared health-related quality of life between asthmatic and healthy children. This study used data from a cross-sectional survey of parents'/guardians of 406 children residing in rural areas. Multinomial logistic regression analysis was used to evaluate association between a categorical outcome variable (No asthma/No asthma symptoms; night-time asthma symptoms only; asthma diagnosis without night-time asthma symptoms; and asthma diagnosis with night-time asthma symptoms) and health-related quality of life indicators. Presence of night-time asthma symptoms among children with asthma was significantly associated with reduced health-related quality of life adjusting for other covariates. Children who had asthma without any night-time asthma symptoms did not have reduced health-related quality of life. Proper control of night-time asthma symptoms may help increase health-related quality of life in children.
authors.affiliation: Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, NC 28223, USA. aarif@uncc.edu
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Arif
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000175:diagnosis*; D002648:Child; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires