The effect of Buscopan on the development of the blow fly Chrysomya megacephala (F.) (Diptera: Calliphoridae).
This work investigated the effects of butylscopolamine bromide, a drug present in the pharmaceutical formulation Buscopan, on the development of Chrysomya megacephala, a blow fly species of considerable forensic and medical importance in Brazil. Larvae exposed to the drug showed a decreased rate of development, with higher drug concentrations further retarding the development. Besides, larvae reared on the presence of the drug showed smaller body weight and body length when compared with larvae reared on the absence of Buscopan. The drug also affected the mortality of the species.
Oliveira
Helena G
HG
Departamento de Zoologia/IB, UNESP-São Paulo State University, Campus de Rio Claro, CP 199, Bela Vista, CEP 13506-900, Rio Claro, SP, Brazil. helenago@gmail.com
Gomes
Guilherme
G
Morlin
José J
JJ
Von Zuben
Cláudio J
CJ
Linhares
Arício X
AX
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002086:Butylscopolammonium Bromide / Q000494:pharmacology*; D004175:Diptera / Q000187:drug effects* / Q000254:growth & development*; D004305:Dose-Response Relationship, Drug; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D018727:Muscarinic Antagonists / Q000494:pharmacology*
D018727:Muscarinic Antagonists; D002086:Butylscopolammonium Bromide