title: Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.
abstract: An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(ii) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN(3))(2+) complex.
authors.affiliation: Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.
authors.forename: Ta-Sheng Andrew
authors.initials: TS
authors.lastname: Tseng
authors.forename: Judith N
authors.initials: JN
authors.lastname: Burstyn
mesh_terms: D003300:Copper / Q000737:chemistry*; D053837:DNA Cleavage; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D047028:Macrocyclic Compounds; D003300:Copper