Polychlorinated naphthalenes in human adipose tissue from New York, USA.
Polychlorinated naphthalenes (PCNs) are persistent, bioaccumulative, and toxic contaminants. Prior to this study, the occurrence of PCNs in human adipose tissues from the USA has not been analyzed. Here, we have measured concentrations of PCNs in human adipose tissue samples collected in New York City during 2003-2005. Concentrations of PCNs were in the range of 61-2500pg/g lipid wt. in males and 21-910pg/g lipid wt. in females. PCN congeners 52/60 (1,2,3,5,7/1,2,4,6,7) and 66/67 (1,2,3,4,6,7/1,2,3,5,6,7) were predominant, collectively accounting for 66% of the total PCN concentrations. Concentrations of PCNs in human adipose tissues were 2-3 orders of magnitude lower than the previously reported concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs). Concentrations of PCNs were not correlated with PCB concentrations. The contribution of PCNs to dioxin-like toxic equivalents (TEQs) in human adipose tissues was estimated to be <1% of the polychlorinated dibenzo-p-dioxin/dibenzofuran (PCDD/F)-TEQs.
Kunisue
Tatsuya
T
Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY 12201-0509, USA.
Johnson-Restrepo
Boris
B
Hilker
David R
DR
Aldous
Kenneth M
KM
Kannan
Kurunthachalam
K
D000273:Adipose Tissue / Q000737:chemistry*; D000328:Adult; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000032:analysis; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D008297:Male; D009281:Naphthalenes / Q000032:analysis*; D009519:New York City; D011078:Polychlorinated Biphenyls / Q000032:analysis; D012737:Sex Factors; D018709:Statistics, Nonparametric
D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D009281:Naphthalenes; C086401:pentabromodiphenyl ether; D011078:Polychlorinated Biphenyls