[Risk factors of hypertension in IgA nephropathy].
OBJECTIVE
To explore the risk factors of hypertension in patients with IgA nephropathy in South China.


METHODS
The clinical and renal pathological data of 280 primary IgA nephropathy patients diagnosed by biopsy were analyzed to extinguish the risk factors of hypertension.


RESULTS
A total of 96 patients were suffered with hypertension (34.3%). A single-variable analysis showed that the age (>or= 40 years), body weight (>or= 60 kg), absence of macrohematuria, duration of disease (>or= 60 months), blood urea nitrogen >or= 8 mmol/L, serum creatinine (>or= 133 micromol/L), hyperuricaemia, degree of 24 h-proteinuria (>or= 1.5 g), segmental glomerular lesions (>or= 25%), globe glomerular sclerosis (>or= 10%), tubular atrophy (>or= 25%), interstitial fibrosis (>or= 25%), interstitial inflammation (>or= 25%) and arteriole hypertrophy (>or= 10%) were all risk factors related to hypertension; multivariate logistic regression analysis showed that serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors.


CONCLUSIONS
Many factors were related the hypertension in patients with IgA nephropathy, while serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors of hypertension.
Li
Shen-heng
SH
Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
Shi
Wei
W
Wang
Wen-jian
WJ
Liang
Xin-ling
XL
Liu
Shuang-xin
SX
Ye
Zhi-ming
ZM
Zhang
Bin
B
He
Chao-sheng
CS
Xia
Yun-feng
YF
Ma
Jian-chao
JC
D000293:Adolescent; D000328:Adult; D000368:Aged; D001835:Body Weight; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D006977:Hypertension, Renal / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors
D003404:Creatinine