Pharmacogenomics and personalized use of drugs.
As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics. Pharmacogenomics is the study of how an individual's genetic inheritance affects the body's response to drugs using the information of human genomics and bioinformatics approaches. It is not only propitious to the rational use of drugs, but also in favor for the personalized drug design.
Wang
Jing-Fang
JF
College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China. dqwei@sjtu.edu.cn.
Wei
Dong-Qing
DQ
Chou
Kuo-Chen
KC
D045303:Cytochromes b / Q000737:chemistry; D015195:Drug Design; D004358:Drug Therapy / Q000639:trends*; D015894:Genome, Human; D005838:Genotype; D006801:Humans; D008958:Models, Molecular; D010597:Pharmacogenetics / Q000379:methods*; D020641:Polymorphism, Single Nucleotide; D011487:Protein Conformation
D045303:Cytochromes b