A simple and sensitive colorimetric pH meter based on DNA conformational switch and gold nanoparticle aggregation.
A simple and rapid colorimetric pH meter has been developed based on the conformational switch of i-motif DNA and non-crosslinking AuNP aggregation, the average accuracy of the nano-meter was found to be +/-0.04 pH unit across the physiological operating range.
Chen
Cuie
C
State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022.
Song
Guangtao
G
Ren
Jinsong
J
Qu
Xiaogang
X
D003124:Colorimetry; D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D012680:Sensitivity and Specificity; D013053:Spectrophotometry
D006046:Gold; D004247:DNA