[Prevalence of arterial hypertension and lipid profile in HIV patients].
OBJECTIVE
It is not known whether human immunodeficiency virus (HIV)-infected patients present, compared to non-HIV controls, higher vascular risk factors. Our objective was to analyze whether there are differences in blood pressure in HIV patients compared to non-HIV controls.


METHODS
We retrospectively analyzed all HIV patients controlled in our centre, who were compared with a control group of blood donors, matched for age and sex, blood pressure and lipid profile. We evaluated the following variables: demographic data, date of HIV diagnosis, presence of lipodystrophy, antiretroviral treatment, duration of this treatment, and vascular risk factors.


RESULTS
We evaluated 740 patients (mean age: 41.8 years; 75% men). We detected a higher prevalence of hypertension in the HIV group (25% vs. 15%) with a significant difference in the mean systolic/diastolic blood pressure between both groups (p < 0.0001). In the HIV group, hypertensives were older than normotensives, and had higher prevalence of lipodystrophy and higher total cholesterol with a shorter disease duration (75 vs 85 months). In the total group of hypertensives, HIV patients were younger than non-HIV (44.2 vs 47.9 years; p < 0.009) and had higher total cholesterol values (5.44 vs 5.18 mmol/l; p < 0.052).


CONCLUSIONS
We found a higher prevalence of hypertension in HIV patients compared with matched controls, as well as a higher prevalence of lipodystrophy and vascular risk factors in hypertensive HIV patients compared with non-hypertensive.
Coloma Conde
Ana G
AG
Servicio de Medicina Interna. Hospital de la Santa Creu i Sant Pau. Barcelona. España. acoloma@santpau.es
Alvarez Albarrán
Maite
M
Roca-Cusachs Coll
Alejandro
A
Domingo Pedrol
Pere
P
Puig Campmany
Mireia
M
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000453:epidemiology*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies
D008076:Cholesterol, HDL; D002784:Cholesterol