[Fatty acid composition of red blood cells in patients with iron-deficiency anemia in relation to the presence of cardiomyopathy].
The purpose of the investigation was to study the fractional composition of fatty acids (FA) of red blood cell membrane lipids in 51 patients with chronic posthemorrhagic iron-deficiency anemia (IDA) of first-third grade in relation to the presence or absence of anemic cardiomyopathy and in 15 healthy individuals. In IDA patients without cardiomyopathy, there was an increase in the sum of saturated FA at the expense of a palmitic acid fraction and a decrease in the sum of unsaturated FA at the expense of arachidonate as compared with these in healthy individuals. In patients with cardiomyopathy-complicated IDA, fatty acid impairments were greater pronounced: the concentrations of myristic and pentadecanoic FAs raised and the relative content of omega 3-polyunsaturated FA reduced.
Goncharova
E V
EV
Govorin
A V
AV
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000150:complications / Q000378:metabolism; D009202:Cardiomyopathies / Q000097:blood* / Q000150:complications / Q000378:metabolism; D016022:Case-Control Studies; D002908:Chronic Disease; D004912:Erythrocytes / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D006801:Humans; D012720:Severity of Illness Index
D005227:Fatty Acids