title: [Advances on progesterone receptor gene].
abstract: The steroid hormone, progesterone, plays a key role in diverse events associated with female reproduction. In humans and other vertebrates, the biological activity of progesterone is mediated by modulation of the transcriptional activity of two progesterone receptors, PGR-A and PGR-B. This review introduced the structure, expression regulation and polymorphism of progesterone receptor gene. The relationship between progesterone receptor gene and reproductive function was also discussed in mammals.
authors.affiliation: Bioengineering Institute of Chongqing University, Chongqing 400030, China. zhangbaoyun418@sina.com
authors.forename: Bao-Yun
authors.initials: BY
authors.lastname: Zhang
authors.forename: Ran
authors.initials: R
authors.lastname: DI
authors.forename: Ming-Xing
authors.initials: MX
authors.lastname: Chu
authors.forename: Ping-Qing
authors.initials: PQ
authors.lastname: Wang
authors.forename: Lang
authors.initials: L
authors.lastname: Lu
mesh_terms: D000818:Animals; D006801:Humans; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011980:Receptors, Progesterone / Q000235:genetics* / Q000378:metabolism; D012098:Reproduction / Q000235:genetics
chemical_list: D011980:Receptors, Progesterone