title: Differences in subgingival microflora of Korean and German periodontal patients.
abstract: OBJECTIVE
  The goal of this study was to characterize the microbiological profile in samples of subgingival plaque taken from periodontal patients with different ethnic origin.
  
  
  METHODS
  178 patients (n=90 from South Korea and n=88 from Germany; age: 45.4 +/- 10.4 years) were diagnosed with severe generalized periodontitis. In all patients the deepest pocket of each quadrant was sampled for subgingival plaque. The four samples per patient were pooled and subsequently analysed with a 16s-RNA-gene probe test.
  
  
  RESULTS
  Prevalence of Aggregatibacter actinomycetemcomitans was significantly higher in German patients (47.7%) compared to Korean patients (26.7%) (p < 0.01, chi(2)-test). For Tannerella forsythia and porphyromonas gingivalis, differences between Germans and Koreans were not as pronounced. A statistically significant difference could also be found for Treponema denticola (Germans: 95.5%, Koreans: 81.1%, p < 0.01, chi(2)-test). After logarithmic transformation, bacterial counts differed for all microorganisms under investigation between Germans and Koreans, even after using a General Linear Model/Analysis of Covariance (GLM/ANCOVA) to adjust for gender, age, smoking status, pocket probing depths (PPD) of sampled teeth, and gingival bleeding index (GBI).
  
  
  CONCLUSIONS
  Depending on their ethnic origin, the microbiological profile of pooled subgingival plaque sample seems to differ significantly between patients of Caucasian and Asian ethnic origin.
authors.affiliation: Department of Operative Dentistry and Periodontology, Section of Periodontology, University Hospital, Ruprecht-Karls-University Heidelberg, Germany. ti-sun_kim@med.uni-heidelberg.de
authors.forename: T S
authors.initials: TS
authors.lastname: Kim
authors.forename: N W
authors.initials: NW
authors.lastname: Kang
authors.forename: Sung-Bum
authors.initials: SB
authors.lastname: Lee
authors.forename: P
authors.initials: P
authors.lastname: Eickholz
authors.forename: B
authors.initials: B
authors.lastname: Pretzl
authors.forename: Chong-Kwan
authors.initials: CK
authors.lastname: Kim
mesh_terms: D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D000704:Analysis of Variance; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000208:ethnology / Q000382:microbiology*; D005260:Female; D020563:Gammaproteobacteria / Q000302:isolation & purification; D005858:Germany; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D010514:Periodontal Pocket / Q000208:ethnology / Q000382:microbiology*; D010518:Periodontitis / Q000208:ethnology / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D015995:Prevalence