title: New therapies in SLE.
abstract: The therapy of systemic lupus erythematosus (SLE), a systemic autoimmune disease of unknown aetiology, is significantly complicated by the diversity of disease manifestations and by a variety of complex immune abnormalities. Recent preclinical studies have shown the therapeutic efficacy of several drugs and/or new compounds, some of which have been tested in clinical trials. This review provides an update on the use of new approaches in SLE and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the management of the disease.
authors.affiliation: Centre of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Ferrera
authors.forename: Gilberto
authors.initials: G
authors.lastname: Filaci
authors.forename: Marta
authors.initials: M
authors.lastname: Rizzi
authors.forename: Ram P
authors.initials: RP
authors.lastname: Singh
authors.forename: Francesco
authors.initials: F
authors.lastname: Indiveri
authors.forename: Bevra H
authors.initials: BH
authors.lastname: Hahn
authors.forename: Antonio
authors.initials: A
authors.lastname: La Cava
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D016503:Drug Delivery Systems; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000276:immunology; D010330:Patents as Topic
chemical_list: D007166:Immunosuppressive Agents