Cladophialophora carrionii: a rare agent of chromoblastomycosis in Rio de Janeiro State, Brazil.
A 73 year-old male farm laborer from a rural area presented a 15 year history of extensive tumoral lesions over his left leg. Histological studies of skin biopsy showed pseudoepitheliomatous hyperplasia and granulomatous chronic inflammatory process with muriform cells, confirming chromoblastomycosis (CBM). Cladophialophora carrionii was isolated in culture. Treatment with itraconazole 400 mg/day for 12 months resulted in complete remission of lesions. As far we aware, this is the first case report of CBM caused by Cladophialophora carrionii in Rio de Janeiro State, Brazil.
Mouchalouat
Marcelle de F
Mde F
Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. marcelle.figueiredo@gmail.com
Galhardo
Maria Clara G
MC
Fialho
Paulo Cezar Monteiro
PC
Coelho
Janice Mery C de Oliveira
JM
Zancopé-Oliveira
Rosely Maria
RM
Valle
Antonio Carlos F do
AC
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D001938:Brazil / Q000453:epidemiology; D002862:Chromoblastomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male
D000935:Antifungal Agents; D017964:Itraconazole