title: Onyx embolization of sporadic angiomyolipoma.
abstract: Percutaneous embolization is the currently preferred treatment of symptomatic or ruptured renal angiomyolipomas (AMLs). Alcohol, microparticles, and coils are usually used. We present what is to our knowledge the first case of successful embolization of a solitary sporadic AML with the use of a new nonadhesive liquid embolic agent (ethylene vinyl alcohol copolymer; Onyx). Onyx injection was slow and controllable and achieved complete tumor devascularization, producing a characteristic appearance like a vascular cast. Short-term follow-up magnetic resonance imaging showed complete tumor necrosis without any recurrent pathologic vessels. The specific features, potential advantages in AML treatment, and technical limitations of this new liquid embolic agent are discussed.
authors.affiliation: Department of Interventional Radiology, Guy's and St. Thomas' Hospital, NHS Foundation Trust, Westminster Bridge and Lambeth Palace Road, SE17EH, London, UK. katsanos@med.upatras.gr
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Katsanos
authors.forename: Tarun
authors.initials: T
authors.lastname: Sabharwal
authors.forename: Farhan
authors.initials: F
authors.lastname: Ahmad
authors.forename: Renato
authors.initials: R
authors.lastname: Dourado
authors.forename: Andreas
authors.initials: A
authors.lastname: Adam
mesh_terms: D000328:Adult; D000792:Angiography; D018207:Angiomyolipoma / Q000000981:diagnostic imaging / Q000628:therapy*; D003287:Contrast Media; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D011145:Polyvinyls / Q000627:therapeutic use*
chemical_list: D003287:Contrast Media; C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide