Stenotrophomonas maltophilia infections of intact skin: a systematic review of the literature.
To highlight the importance of intact skin infection syndromes caused by Stenotrophomonas maltophilia, we review 17 reported cases. Skin infection syndrome presentations included metastatic cellulitis (58%), primary cellulitis (23%), and ecthyma gangrenosum (17%). Associated risk factors were hematologic malignancies and chemotherapy (94%), neutropenia (94%), presence of central venous catheter (17%), and exposure to broad-spectrum antibiotics (84%). The diagnosis was supported by cultures of skin biopsy specimens (35%), blood cultures (24%), or both (41%). Trimethoprim-sulfamethoxazole was the treatment of choice (76%), and outcomes were favorable (71%).
Bin Abdulhak
Aref A
AA
Department of Medicine, King Fahd Medical City, Riyadh, Saudi Arabia.
Zimmerman
Valerie
V
Al Beirouti
Bassim T
BT
Baddour
Larry M
LM
Tleyjeh
Imad M
IM
D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D015662:Trimethoprim, Sulfamethoxazole Drug Combination