title: [Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole].
abstract: BACKGROUND
  Vaginitis is an inflammatory process in vaginal mucosa that affects millions of woman worldwide.
  
  
  OBJECTIVE
  To evaluate prevalence perception and prescription preference among Latin-American gyneco-obstetricians in mixed vaginitis, and to identify attributes of various active principles.
  
  
  METHODS
  multicentric and transversal study during January 2008. Close Up was used to poll gyneco-obstetricians prescribing clyndamicin plus ketoconazole. 1,198 gyneco-obstetricians were selected to answer a poll (scales and measuring attributes) to identify differences among various therapeutic schemes to mixed vaginitis.
  
  
  RESULTS
  34% of gyneco-obstetricians consider that 30 to 50% of them patients had mixed vaginitis, 38% consider a 50 to 70% of its prevalence, and 20% a 70% or higher figure. In a bad to excellent scale, 97% had very good to excellent results with antimycotic and antibacterial mix, 73% had a bad to good result with antimycotics alone and 79% with antibacterial alone. Clyndamicin plus ketoconazole had a meaningful difference from mean results (standard), and from the second best mix (metronidazole plus nystatin), with a rapid itch healing, efficacy, and relapse decrease. Metronidazole plus nystatin had the highest score in tolerance and treatment period.
  
  
  CONCLUSIONS
  90% of polled Latin-American obstetricians prescribe clyndamicin plus ketoconazole as the best available treatment to mixed vaginitis.
authors.affiliation: Clínica de Atención Médica Integral para la Mujer SC, Naucalpan, Estado de México, México. jhernandezb@atmim.com
authors.forename: José Alberto
authors.initials: JA
authors.lastname: Hernández Bueno
authors.forename: Alejandro
authors.initials: A
authors.lastname: Vázquez Alanís
authors.forename: Claudia
authors.initials: C
authors.lastname: Olguín Ramírez
authors.forename: Pablo F
authors.initials: PF
authors.lastname: Dumet Hinostroza
authors.forename: Miguel
authors.initials: M
authors.lastname: Gutiérrez Ramos
authors.forename: Daniel
authors.initials: D
authors.lastname: De Zordo
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D002981:Clindamycin / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use*; D007843:Latin America / Q000453:epidemiology; D010818:Practice Patterns, Physicians'; D015995:Prevalence; D014627:Vaginitis / Q000188:drug therapy* / Q000453:epidemiology*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004338:Drug Combinations; D002981:Clindamycin; D007654:Ketoconazole