title: How to shape cells and influence polarized protein trafficking.
abstract: Posttranslational modifications of tubulin likely generate the functional diversity of microtubules. In this issue of Developmental Cell, Loktev and colleagues (2008) describe a novel protein BBIP10 with dual roles: it is required for ciliogenesis as well as acetylation and stabilization of microtubules.
authors.affiliation: Molecular Medicine Unit, Institute of Child Health, University College London, London, UK.
authors.forename: Anna
authors.initials: A
authors.lastname: Diaz-Font
authors.forename: Philip L
authors.initials: PL
authors.lastname: Beales
mesh_terms: D000107:Acetylation; D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry* / Q000378:metabolism; D002696:Chlamydomonas / Q000378:metabolism; D006801:Humans; D008239:Lysine / Q000737:chemistry; D008870:Microtubules / Q000378:metabolism; D008954:Models, Biological; D009842:Oligopeptides; D010446:Peptide Fragments; D011499:Protein Processing, Post-Translational; D021381:Protein Transport / Q000235:genetics*; D015398:Signal Transduction; D013768:Tetrahymena / Q000378:metabolism; D029961:Zebrafish Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D009842:Oligopeptides; D010446:Peptide Fragments; D029961:Zebrafish Proteins; C534297:bbip1 protein, zebrafish; C085462:benzoylbenzoyl-troponin I inhibitory peptide (104-115); D008239:Lysine