title: A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles.
abstract: The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an alpha-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction.
authors.affiliation: Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15260, USA.
authors.forename: Filip
authors.initials: F
authors.lastname: Petronijevic
authors.forename: Cody
authors.initials: C
authors.lastname: Timmons
authors.forename: Anthony
authors.initials: A
authors.lastname: Cuzzupe
authors.forename: Peter
authors.initials: P
authors.lastname: Wipf
mesh_terms: D003500:Cyclization; D004583:Electrons; D005663:Furans / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D007202:Indicators and Reagents; D007211:Indoles / Q000138:chemical synthesis* / Q000528:radiation effects; D008094:Lithium / Q000737:chemistry; D008872:Microwaves
chemical_list: D005663:Furans; D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D007211:Indoles; D008094:Lithium