In silico characterization of DNA motifs with particular reference to promoters and terminators.
Knowledge of the regulatory elements contained within bacteriophage genomes forms the basis for understanding genomic expression and organization. The in silico prediction of promoter and terminator sequences in phage genomes is a first step towards this understanding. In this chapter, a number of programs and resources to identify regulatory elements are listed and discussed. Combining the available web-resources and literature data optimizes these predictions and can thus aid in a more directed experimental identification of these regulatory elements.
Lavigne
Rob
R
Department of Biosystems, Division of Gene Technology, Katholieke Universiteit Leuven, Leuven, Belgium.
Villegas
André
A
Kropinksi
Andrew M
AM
D001435:Bacteriophages / Q000235:genetics; D019295:Computational Biology / Q000379:methods; D004279:DNA, Viral / Q000032:analysis / Q000235:genetics*; D016679:Genome, Viral / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics*; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*; D013728:Terminator Regions, Genetic / Q000235:genetics*
D004279:DNA, Viral