title: Recombinant factor VIIa in a case of pontine hemorrhage.
abstract: A 59-year-old lady presented with hypertensive hemorrhage involving the pons. Since she presented within 3 hours of onset of the stroke, recombinant factor VIIa was administered. From a state of altered sensorium there was a rapid recovery of consciousness followed by gradual improvement in limb weakness. Serial CT scans of the brain revealed no further expansion of the hematoma. The hematoma progressively resolved. Recombinant factor VIIa could be an attractive therapeutic option in treating hemorrhages at critical sites like brainstem where expansion of hematoma could be fatal.
authors.affiliation: Department of Neurosciences, Apollo Speciality Hospitals, Lake View Road, KK Nagar, Madurai, Tamil Nadu, India-625 020.
authors.forename: S
authors.initials: S
authors.lastname: Meenakshi-Sundaram
authors.forename: T C Vijay
authors.initials: TC
authors.lastname: Anand
authors.forename: G
authors.initials: G
authors.lastname: Suriyakumar
authors.forename: Rohini
authors.initials: R
authors.lastname: Sridhar
authors.forename: S
authors.initials: S
authors.lastname: Sundararajan
authors.forename: Bharathi
authors.initials: B
authors.lastname: Sundar
mesh_terms: D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006406:Hematoma / Q000188:drug therapy; D006801:Humans; D020299:Intracranial Hemorrhage, Hypertensive / Q000188:drug therapy*; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa