title: Psoriasis in France and associated risk factors: results of a case-control study based on a large community survey.
abstract: BACKGROUND
  Risk factors for psoriasis have been identified.
  
  
  OBJECTIVE
  To precisely define these associated factors.
  
  
  METHODS
  A survey was conducted using a questionnaire on a representative sample of the French population. A case-control study was conducted. Cases were persons who declared having had psoriasis during the previous 12 months. For each case, 3 matched controls were selected. Cases and controls were compared using univariate and multivariate analyses.
  
  
  RESULTS
  The questionnaire was filled out and returned by 6,887 (68.9%) of 10,000 subjects aged 15 years and over; 356 cases were identified. In multivariate analysis, a higher body mass index, current and former smoking habits and beta-blocker intake were independently associated with a higher risk of psoriasis; intake of statins was associated with a decreased risk (p < 0.05).
  
  
  CONCLUSIONS
  We confirmed the association of overweight, smoking habits and beta-blocker intake with psoriasis and reported a decreased risk associated with statin intake.
authors.affiliation: Department of Dermatology, Albert Chenevier-Henri Mondor, Faculty of Medicine, Paris 12 University, Créteil, France. pierre.wolkenstein@hmn.aphp.fr
authors.forename: P
authors.initials: P
authors.lastname: Wolkenstein
authors.forename: J
authors.initials: J
authors.lastname: Revuz
authors.forename: J C
authors.initials: JC
authors.lastname: Roujeau
authors.forename: G
authors.initials: G
authors.lastname: Bonnelye
authors.forename: J J
authors.initials: JJ
authors.lastname: Grob
authors.forename: S
authors.initials: S
authors.lastname: Bastuji-Garin
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000704:Analysis of Variance; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006306:Health Surveys; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D050177:Overweight / Q000150:complications*; D011565:Psoriasis / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D011795:Surveys and Questionnaires
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors