Histological, histomorphometric, and radiographic evaluation of a sinus augmentation with a new bone allograft: a clinical case report.
OBJECTIVE
This case report documents the histological, histomorphometric, and radiographic effects of a new radiated-preserved bone allograft for sinus elevation procedures.


METHODS
This unique bone substitute differs from other forms of bone allograft processed through the standard cryopreservation method. Histology from bone biopsy core samples revealed newly formed bone with a well-organized lamellar bone structure in general and remaining particles were observed in contact with surrounding newly-formed bone.


RESULTS
Histomorphometric results demonstrated an average new bone formation of 31.8%. Radiographic linear data demonstrated an 8.49% +/- 6.77% graft resorption from baseline to 6 months.


CONCLUSIONS
The outcome of this report suggests that this bone allograft could be successfully used in sinus lifting procedures. It encourages further research of this radiated-preserved bone allograft material in oral and maxillofacial reconstruction.
Gapski
Ricardo
R
GT International Implant Institute, Curitiba, Brazil. rgapski@pitimplant.com
Misch
Carl
C
Stapleton
David
D
Mullins
Stephanie
S
Cobb
Charles
C
Vansanthan
Asvin
A
Reissner
Marc
M
D001419:Bacteria / Q000528:radiation effects; D001857:Bone Matrix / Q000637:transplantation; D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods*; D054893:Cone-Beam Computed Tomography; D015925:Cryopreservation / Q000379:methods*; D017886:Durapatite; D005260:Female; D006801:Humans; D008443:Maxillary Sinus / Q000000981:diagnostic imaging / Q000601:surgery*; D008875:Middle Aged; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*; D054457:Tissue Scaffolds; D014184:Transplantation, Homologous; D014779:Virus Replication / Q000528:radiation effects
D018786:Bone Substitutes; D017886:Durapatite