Enhanced biocompatibility of Co-Cr implant material by Ti coating and micro-arc oxidation.
The biocompatibility of Co-Cr alloy was significantly improved by forming a rough TiO(2) layer on its surface. The TiO(2) layer was formed by coating the Co-Cr alloy with titanium (Ti) through electron beam deposition followed by microarc oxidation (MAO). When Ti was coated on the surface, the biocompatibility of the Co-Cr alloy was enhanced and it was further improved by the MAO treatment. There were close relationships between the phase, morphology, and thickness of the TiO(2) layer and the applied voltage. The biocompatibility of the specimens coated with Ti and subjected to MAO treatment was evaluated by in vitro alkaline phosphatase activity tests.
Han
Cheol-Min
CM
Department of Materials Science and Engineering, Seoul National University, Seoul 151-744, Korea.
Kim
Hyoun-Ee
HE
Kim
Yong-Sik
YS
Han
Suk-Ku
SK
D016475:3T3 Cells; D000818:Animals; D001672:Biocompatible Materials; D002857:Chromium; D003035:Cobalt; D051379:Mice; D008855:Microscopy, Electron, Scanning; D010084:Oxidation-Reduction; D014025:Titanium; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D002857:Chromium; D003035:Cobalt; D014025:Titanium