[Clinical comparison of male and female patients with pulmonary disease caused by Mycobacterium avium complex (P-MAC)].
OBJECTIVE
The objective of this study was to clarify clinical feature of Pulmonary Mycobacterium avium complex disease (P-MAC).


METHODS
The present study was performed in 120 patients with P-MAC diagnosed during the period from January 2000 to March 2007. We divided P-MAC patients into four groups by the clinical disease type and gender, and retrospectively examined the clinical characteristics.


RESULTS
The subjects were 15 male (NB-M) and 71 female (NB-F) patients with nodular bronchiectatic disease (NB), and 24 male (FC-M) and 10 female (FC-F) patients with fibrocavitary disease (FC). The average age was lowest in the NB-F group (58.0 yrs), and highest in the FC-M group (65.8 yrs). There were 17 patients in the FC-M group and only two patients in the FC-F group with a history of smoking. The average body mass index (BMI) was 16.9, with the lowest value in the FC-F group. In the FC-M group, most of the patients had underlying pulmonary disease, whereas in the FC-F group, only four patients had underlying old pulmonary tuberculosis. The average anterior-posterior dimension was 75.2 mm, being lowest in the FC-F group, and more than 90 mm in the other groups. The proportion of refractory cases was lowest in the NB-M group.


CONCLUSIONS
We thought that we were able to clarify characteristics of patients with disease caused by MAC by analyzing the types of the disease separately in men and women.
Morimoto
Kozo
K
Department of Respiratory Medicine, Japanese Red Cross Medical Center. aquablueblue@yahoo.co.jp
Ishikawa
Rie
R
Moriya
Atsuko
A
Masunaga
Aiko
A
Kamiya
Hiroyuki
H
Ando
Tsunehiro
T
Ikushima
Souichiro
S
Oritsu
Masaru
M
D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage; D015992:Body Mass Index; D005260:Female; D005783:Gender Identity; D006801:Humans; D008297:Male; D008875:Middle Aged; D015270:Mycobacterium avium-intracellulare Infection / Q000145:classification / Q000188:drug therapy / Q000503:physiopathology; D012189:Retrospective Studies; D012907:Smoking; D014397:Tuberculosis, Pulmonary / Q000145:classification / Q000188:drug therapy / Q000503:physiopathology
D000995:Antitubercular Agents