Diffuse hemangiomatosis with predominant central nervous system involvement.
Diffuse neonatal hemangiomatosis presents with multiple, progressive, rapidly growing cutaneous hemangiomas associated with widespread visceral hemangiomas in the liver, lungs, gastrointestinal tract, brain, and meninges. Described here is a case of diffuse neonatal hemangiomatosis with predominant central nervous system involvement. The early appearance of central nervous system lesions on imaging can overlap with that of cavernous malformations, confounding diagnosis; however, rapid growth, response to steroids, cystic appearance with sedimentation levels of the mature lesions, and involvement of other visceral organs can help confirm the diagnosis.
Al-Kaabi
Atheer
A
Section of Neurology, Department of Internal Medicine, University of Manitoba, Health Sciences Centre, Winnipeg, Manitoba, Canada.
Yanofsky
Rochelle
R
Bunge
Martin
M
Hyman
Jeff
J
Rafay
Mubeen F
MF
D020787:Central Nervous System Venous Angioma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D020786:Hemangioma, Cavernous, Central Nervous System / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis; D016896:Treatment Outcome
D005938:Glucocorticoids; D003907:Dexamethasone