title: Very late thrombosis of drug-eluting stents: a brief literature review and case example.
abstract: Thrombosis late after implantation is an infrequent but increasingly recognized complication following revascularization with drug-eluting stents (DES). The window of vulnerability for this complication with DES remains undefined. Intermediate-term follow up from pivotal trials and registries suggests continuous separation of event curves out to at least 3 years. We briefly review the evolving body of literature on DES thrombosis and report a case of very late thrombosis 53 months after implantation of a sirolimus-eluting stent. The event occurred despite chronic aspirin monotherapy and represents the longest latency from implantation to thrombosis described in the literature for a DES.
authors.affiliation: Department of Cardiology, Rashid Hospital, Dubai, United Arab Emirates. skacardio@yahoo.com
authors.forename: Sanjeev Kumar
authors.initials: SK
authors.lastname: Agarwal
authors.forename: Fayaz
authors.initials: F
authors.lastname: Shawl
authors.forename: Venkatesh K
authors.initials: VK
authors.lastname: Raman
authors.forename: Azan Salim
authors.initials: AS
authors.lastname: Binbrek
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000209:etiology*; D003328:Coronary Thrombosis / Q000209:etiology*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors