Polyphenols isolated from antiradical extracts of Mallotus metcalfianus.
Six flavonoids including two new flavones, luteolin 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside), chrysoeriol-7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside) and a mixture of two pairs of diastereoisomeric flavonolignans, (+/-)-hydnocarpin 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside)/(+/-)-hydnocarpin-D 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside) with a 2:1 ratio were isolated from the whole plant of Mallotus metcalfianus Croizat, in addition to 10 known compounds. Their structures were evaluated on the basis of different spectroscopic methods, including extensive 1D and 2D NMR spectroscopy. Some extracts have moderate antimicrobial properties and interesting antiradical (DPPH) activity, as well as some compounds isolated from this species. Tannins were also identified in some active extracts.
Rivière
Céline
C
Université Catholique de Louvain, Louvain Drug Research Institute, CHAM Unit, UCL 7230, Avenue E. Mounier 7, B-1200 Brussels, Belgium.
Hong
Van Nguyen Thi
VN
Pieters
Luc
L
Dejaegher
Bieke
B
Heyden
Yvan Vander
YV
Van
Minh Chau
MC
Quetin-Leclercq
Joëlle
J
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry*; D036461:Mallotus Plant / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D059808:Polyphenols
D000900:Anti-Bacterial Agents; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols