Resolution of persistent Pediococcus bacteremia with daptomycin treatment: case report and review of the literature.
A case of bacteremia caused by Pediococcus acidilactici occurring in a patient with metastatic adenocarcinoma of the gallbladder is described. The bacteremia persisted despite an antimicrobial regimen of vancomycin, ciprofloxacin, metronidazole, and caspofungin. Within 36 h of switching the vancomycin to daptomycin (6 mg/kg per day), the bacteremia resolved and the patient improved clinically. Previous reports of human pediococcal infection are also reviewed.
Suh
Byungse
B
Section of Infectious Diseases, Temple University School of Medicine, Philadelphia, PA 19140, USA. bingsuh@temple.edu
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D017576:Daptomycin / Q000627:therapeutic use*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D010376:Pediococcus / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D017576:Daptomycin