How to study lipidomes.
Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area of lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform and for the hypothesis-driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.
Seppänen-Laakso
Tuulikki
T
VTT Technical Research Centre of Finland, Espoo, Finland.
Oresic
Matej
M
D000818:Animals; D001695:Biology / Q000379:methods*; D019295:Computational Biology; D006801:Humans; D050356:Lipid Metabolism / Q000235:genetics / Q000502:physiology; D008055:Lipids / Q000032:analysis* / Q000737:chemistry* / Q000502:physiology; D013058:Mass Spectrometry
D008055:Lipids