title: Treatment of tendon and muscle using platelet-rich plasma.
abstract: Tendon and muscle injuries are common in elite and weekend athletes. Treatment of these injuries in both groups is rapidly evolving. Sports medicine patients are demanding better and less invasive solutions for all types of musculoskeletal disorders. In this context, platelet-rich plasma (PRP) has emerged as a potential solution. PRP is a fraction of whole blood containing concentrated growth factors and proteins. These cytokines direct tissue healing through autocrine and paracrine effects. The number of basic science, animal, and human investigations of PRP for tendon and muscle injuries worldwide has risen sharply in recent years. These studies are helping clinicians better understand the mechanisms of PRP and are guiding novel treatment protocols. In this paper, the value of PRP as a treatment for acute or chronic tendon and muscle disorders is explored.
authors.affiliation: Department of Orthopedic Surgery, Menlo Medical Clinic, Stanford University Medical Center, 1300 Crane Street, Menlo Park, CA 94025, USA. am@totaltendon.com
authors.forename: Allan
authors.initials: A
authors.lastname: Mishra
authors.forename: James
authors.initials: J
authors.lastname: Woodall
authors.forename: Amy
authors.initials: A
authors.lastname: Vieira
mesh_terms: D001792:Blood Platelets; D016207:Cytokines; D006801:Humans; D009140:Musculoskeletal Diseases / Q000097:blood / Q000534:rehabilitation / Q000628:therapy; D053657:Platelet-Rich Plasma; D052256:Tendinopathy / Q000097:blood / Q000534:rehabilitation / Q000628:therapy; D013708:Tendon Injuries / Q000097:blood / Q000534:rehabilitation / Q000628:therapy*
chemical_list: D016207:Cytokines