title: A database of mitochondrial DNA hypervariable regions I and II sequences of individuals from Slovakia.
abstract: In order to identify polymorphic positions and to determine their frequencies and the frequency of haplotypes in the human mitochondrial control region, two hypervariable regions (HV1 and HV2) of the mitochondrial DNA (mtDNA) of 374 unrelated individuals from Slovakia were amplified and sequenced. Sequence comparison led to the identification of 284 mitochondrial lineages as defined by 163 variable sites. Genetic diversity (GD) was estimated at 0.997 and the probability of two randomly selected individuals from population having identical mtDNA types (random match probability, RMP) for the both regions is 0.60%.
authors.affiliation: Department of Forensic Biology and DNA Analyse, Institute of Forensic Science of Police Corps, Bratislava, Slovak Republic. lehocky@keupz.minv.sk
authors.forename: Ivan
authors.initials: I
authors.lastname: Lehocký
authors.forename: Marian
authors.initials: M
authors.lastname: Baldovic
authors.forename: Ludevít
authors.initials: L
authors.lastname: Kádasi
authors.forename: Ene
authors.initials: E
authors.lastname: Metspalu
mesh_terms: D001483:Base Sequence; D022801:Complementarity Determining Regions / Q000235:genetics*; D004247:DNA / Q000097:blood / Q000235:genetics* / Q000302:isolation & purification; D004272:DNA, Mitochondrial / Q000235:genetics*; D030541:Databases, Genetic; D053803:Forensic Genetics / Q000379:methods* / Q000592:standards; D005784:Gene Amplification; D014644:Genetic Variation; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods; D011336:Probability; D018154:Slovakia
chemical_list: D022801:Complementarity Determining Regions; D004272:DNA, Mitochondrial; D004247:DNA