title: From molecular shape to potent bioactive agents I: bioisosteric replacement of molecular fragments.
authors.affiliation: Goethe-University, Institute of Organic Chemistry and Chemical Biology, LiFF/ZAFES, Siesmayerstr. 70, 60323 Frankfurt am Main, Germany.
authors.forename: Ewgenij
authors.initials: E
authors.lastname: Proschak
authors.forename: Heiko
authors.initials: H
authors.lastname: Zettl
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Tanrikulu
authors.forename: Martin
authors.initials: M
authors.lastname: Weisel
authors.forename: Jan M
authors.initials: JM
authors.lastname: Kriegl
authors.forename: Oliver
authors.initials: O
authors.lastname: Rau
authors.forename: Manfred
authors.initials: M
authors.lastname: Schubert-Zsilavecz
authors.forename: Gisbert
authors.initials: G
authors.lastname: Schneider
mesh_terms: D000818:Animals; D019556:COS Cells; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D003198:Computer Simulation; D015195:Drug Design; D020128:Inhibitory Concentration 50; D047493:PPAR alpha / Q000819:agonists* / Q000737:chemistry*; D047495:PPAR gamma / Q000819:agonists* / Q000737:chemistry*; D011422:Propionates / Q000737:chemistry* / Q000494:pharmacology; D012984:Software; D013329:Structure-Activity Relationship
chemical_list: D047493:PPAR alpha; D047495:PPAR gamma; D011422:Propionates