title: The predictive brain state: asynchrony in disorders of attention?
abstract: It is postulated that a key function of attention in goal-oriented behavior is to reduce performance variability by generating anticipatory neural activity that can be synchronized with expected sensory information. A network encompassing the prefrontal cortex, parietal lobe, and cerebellum may be critical in the maintenance and timing of such predictive neural activity. Dysfunction of this temporal process may constitute a fundamental defect in attention, causing working memory problems, distractibility, and decreased awareness.
authors.affiliation: Department of Neurological Surgery, Weill Cornell Medical College, New York, NY, USA. jam@ghajar.net
authors.forename: Jamshid
authors.initials: J
authors.lastname: Ghajar
authors.forename: Richard B
authors.initials: RB
authors.lastname: Ivry
mesh_terms: D001288:Attention / Q000502:physiology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000473:pathology*; D001921:Brain / Q000473:pathology* / Q000503:physiopathology*; D001931:Brain Mapping; D006801:Humans; D008570:Memory, Short-Term / Q000502:physiology; D009434:Neural Pathways / Q000503:physiopathology; D017603:Signal Detection, Psychological / Q000502:physiology