Pyridine-based lanthanide complexes: towards bimodal agents operating as near infrared luminescent and MRI reporters.
We report two prototype Ln(3+) complexes that address requirements for both MRI and luminescence imaging and we demonstrate that the presence of two H(2)O molecules bound to the Ln(3+), beneficial for MRI applications of the Gd(3+) analogue, is not a major limitation for the development of NIR luminescent agents.
Pellegatti
Laurent
L
Centre de Biophysique Moléculaire, CNRS, 45071 Orléans, France.
Zhang
Jian
J
Drahos
Bohuslav
B
Villette
Sandrine
S
Suzenet
Franck
F
Guillaumet
Gérald
G
Petoud
Stéphane
S
Tóth
Eva
E
D028581:Lanthanoid Series Elements / Q000737:chemistry*; D049449:Luminescence; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011725:Pyridines / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
D028581:Lanthanoid Series Elements; D011725:Pyridines; C023666:pyridine