title: Brugada syndrome in a north Indian female-a case report.
abstract: The Brugada syndrome is an autosomal dominant disease with incomplete penetrance, which may cause syncope and sudden cardiac death in young individuals with a normal heart. It is characterized by an electrocardiographic pattern of complete or incomplete right bundle branch block and ST-segment elevation in leads V1-V3. Mutations in gene encoding for cardiac sodium channel SCN5A is linked to this syndrome in 20-25% patients. Several conditions producing Brugada-like ECG patterns should be borne in mind and excluded before making a diagnosis of the Brugada syndrome. The management of this syndrome is difficult as pharmacological agents are not universally effective. The mode of treatment recommended by the majority of cardiac electro-physiologists is implantation of a cardioverter defibrillator. We report the first case of a 40-year-old Indian lady who presented with a history of aborted sudden cardiac death with recurrent ventricular arrhythmias and an electrocardiogram (ECG) pattern of type 1 Brugada syndrome, and underwent successful implantable cardioverter defibrillator implantation.
authors.affiliation: Department of Cardiology and Heart Research Centre, Christian Medical College and Hospital, Ludhiana.
authors.forename: Kapil
authors.initials: K
authors.lastname: Chattree
authors.forename: Tm
authors.initials: T
authors.lastname: Jaison
authors.forename: Charles
authors.initials: C
authors.lastname: Itty
authors.forename: Sandeep
authors.initials: S
authors.lastname: Chopra