Skeletal muscle ultrasound: correlation between fibrous tissue and echo intensity.
In this study, we examined the correlation between muscle ultrasound and muscle structure. Echo intensity (EI) of 14 muscles of two golden retriever muscular dystrophy dogs was correlated to the percentage interstitial fibrous tissue and fat in muscle biopsy. A significant correlation between interstitial fibrous tissue and EI was found (r = 0.87; p < 0.001). The separate influence of interstitial fat on muscle EI could not be established as only little fat was present. We conclude that fibrous tissue causes increased muscle EI. The high correlation between interstitial fibrous tissue and EI makes ultrasound a reliable method to determine severity of structural muscle changes.
Pillen
Sigrid
S
Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. s.pillen@cukz.umcn.nl
Tak
Ramon O
RO
Zwarts
Machiel J
MJ
Lammens
Martin M Y
MM
Verrijp
Kiek N
KN
Arts
Ilse M P
IM
van der Laak
Jeroen A
JA
Hoogerbrugge
Peter M
PM
van Engelen
Baziel G M
BG
Verrips
Aad
A
D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000473:pathology; D000818:Animals; D001706:Biopsy; D004195:Disease Models, Animal; D004285:Dogs; D005355:Fibrosis / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging* / Q000473:pathology; D009137:Muscular Dystrophy, Animal / Q000000981:diagnostic imaging* / Q000473:pathology; D015203:Reproducibility of Results; D014463:Ultrasonography