[Morphogenesis of acetate-induced gastric ulcer upon chronic exposure to the pesticide hexachlorocyclohexane].
Morphological, histochemical, and histoenzymatic studies were employed to study the morphogenetic features of acetate-induced gastric ulcer in 40 rats during chronic enteral administration of the organic chlorine pesticide hexachlorocyclohexane. The authors first established the structural and metabolic bases of mucosal regeneration defects in the region of an ulcer upon chronic enteral exposure to the toxic agent and the dose dependence of the chronic nature of acute gastric ulcer.
Rasulov
M T
MT
Shahknazarov
A M
AM
Shakhnazarov
M A
MA
D000085:Acetates / Q000633:toxicity; D000818:Animals; D002908:Chronic Disease; D004195:Disease Models, Animal; D004781:Environmental Exposure / Q000009:adverse effects*; D001556:Hexachlorocyclohexane / Q000009:adverse effects*; D007306:Insecticides / Q000009:adverse effects*; D008297:Male; D011379:Prognosis; D051381:Rats; D012038:Regeneration / Q000187:drug effects*; D013270:Stomach / Q000502:physiology*; D013276:Stomach Ulcer / Q000139:chemically induced / Q000473:pathology*
D000085:Acetates; D007306:Insecticides; D001556:Hexachlorocyclohexane