title: [Differential expressed genes in eutopic endometrium of endometriosis patients: comparison between Uygur and Han women in Xianjiang].
abstract: OBJECTIVE
  To investigate the reason why the incidence of endometriosis (EM) is lower in the Uygur women than in the Han women.
  
  
  METHODS
  Eutopic and ectopic endometrium samples were obtained by operation and biopsy from 26 EM patients, 10 Uygur women and 16 Han women and analyzed with a gene expression microarray containing the cDNAs of 22 000 human genes. Twenty-two women, 10 Uygur and 12 Han, were used as controls.
  
  
  RESULTS
  Eleven differentially expressed genes, 7 up-regulated and 6 down-regulated, were screened out from the eutopic endometrium of the Uygur women with EM. 58 differential expressed genes were screened out from the in eutopic endometrium of the Han women with EM, 53 being up-regulated and 5 down-regulated. Five genes were screened out in both groups, 3 being up-regulated and 2 down-regulated.
  
  
  CONCLUSIONS
  The number of differentially expressed genes of the Uygur women with EM is lower than that of the Han women with EM, which may be the cause of relative low incidence of EM among Uygur women.
authors.affiliation: Department of Gynecology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
authors.forename: Aili
authors.initials: A
authors.lastname: Aixingzi
authors.forename: Yan
authors.initials: Y
authors.lastname: Ding
authors.forename: Jun-Qi
authors.initials: JQ
authors.lastname: Ma
authors.forename: Zhi-Fang
authors.initials: ZF
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People / Q000235:genetics; D002681:China; D004715:Endometriosis / Q000208:ethnology / Q000235:genetics*; D004717:Endometrium / Q000378:metabolism* / Q000473:pathology; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D055815:Young Adult