Isolation and production of cells suitable for human therapy: challenges ahead.
Considerable practical hurdles must be overcome prior to the broad application of stem cell therapies. We outline challenges that may vary across different models of cell therapy, including the following broad concepts: issues related to the sourcing of material, and issues related to product manufacturing, shipping, storage and tracking, and standardization.
Ahrlund-Richter
Lars
L
Department of Woman and Child Health, Karolinska Institutet, 171 76 Stockholm, Sweden.
De Luca
Michele
M
Marshak
Daniel R
DR
Munsie
Megan
M
Veiga
Anna
A
Rao
Mahendra
M
D002469:Cell Separation / Q000379:methods*; D002478:Cells, Cultured; D005615:Freezing; D006801:Humans; D007391:International Cooperation; D033581:Stem Cell Transplantation / Q000331:legislation & jurisprudence / Q000592:standards; D013234:Stem Cells / Q000378:metabolism; D014186:Transportation; D016896:Treatment Outcome