Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi'an city of Shaanxi Province.
Fifteen autosomal STRs loci were analyzed from a population sample of 446 unrelated healthy individuals of Chinese Han population residing in Xi'an city of Shaanxi Province using a multiplex PCR system. We report allele frequencies distribution and statistical parameters for all STR loci, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA. The observed genotype frequencies and expected of genotype frequencies were evaluated by chi(2)-test and the Fisher exact tests. Chi-Square test showed all STR loci were in Hardy-Weinberg equilibrium (p<0.05). Our studied population data were compared with the previously published population data of other ethnics or areas. After comparing, significant differences were found between Chinese Han population in Xi'an and Korean, Tibetan, Uigur, Chinese Han population in Guangdong Province, Hui population, Chinese Salar, Dongxiang and Tu ethnic minority living in Qinghai Province of China at some loci. The forensic parameters from the data showed high values. The data in the present study can be used greatly for routine forensic application in the region of Xi'an city.
Wu
Yuan-Ming
YM
Department of Pathophysiology, The Fmmu Center for DNA Typing, The Fourth Military Medical University, Shaanxi Province, China. wuym@fmmu.edu.cn
Zhang
Xiao-Nan
XN
Zhou
You
Y
Chen
Zhi-Yang
ZY
Wang
Xiao-Bin
XB
D000483:Alleles; D016009:Chi-Square Distribution; D002681:China; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D016172:DNA Fingerprinting; D019075:Electrophoresis, Capillary; D005006:Ethnicity / Q000235:genetics*; D044707:Forensic Sciences; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D005843:Geography; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011786:Quality Control; D012015:Reference Standards; D014505:Urban Population
D004247:DNA