Case report: TEN in a patient with black skin--blister fluid for rapid diagnosis.
Toxic epidermal necrolysis (TEN) is a rare, potentially life-threatening bullous drug reaction. Rapid diagnosis of TEN can lower the mortality rate when the offending drug is withdrawn immediately. Simple diagnostic tools such as cytology of skin blisters may be useful if rapid diagnosis is needed, in particular if standard histopathology service fails. An even faster bedside test for TEN in patients with black skin is color evaluation of skin blister fluid.
Buslau
Michael
M
Department of Dermatology, Kantonsspital Schaffhausen, Switzerland. michael.buslau@kssh.ch
D000328:Adult; D001741:Black or African American; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001826:Body Fluids / Q000737:chemistry*; D001991:Bronchitis / Q000150:complications / Q000188:drug therapy; D003116:Color; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D015603:Keratinocytes / Q000737:chemistry; D008543:Melanins / Q000032:analysis; D052016:Mucositis / Q000139:chemically induced; D019095:Point-of-Care Systems; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000209:etiology; D013280:Stomatitis / Q000139:chemically induced; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D008543:Melanins; D015662:Trimethoprim, Sulfamethoxazole Drug Combination