title: [Safety and effectiveness of central vein catheters indwelling with subcutaneous port in patients undergoing chemotherapy].
abstract: OBJECTIVE
  To investigate the safety and effectiveness of 3 methods of central vein catheters indwelling in cancer patients undergoing chemotherapy.
  
  
  METHODS
  120 cancer patients undergoing long-term chemotherapy (9 months-2 years)were divided into 3 equal groups to be treated via peripherally inserted central catheter(PICC), untunneled central venous catheter (CVC) by repeat venipuncture (20 through jugular vein and 20 through subclavian vein), and implanted subinfuse-port (PORT, 20 through jugular vein and 20 through subclavian vein). The complications of implantation and quality of life were compared.
  
  
  RESULTS
  The early complication of the PICC group was malposition of the tip of catheters; and the early complications of the CVC group included hematoma in the jugular vein subgroup and pneumothorax in the subclavian vein subgroup. The incidence rates of catheter obstruction and thrombosis of the PORT group were significantly higher than those of the other two groups (all P < 0.05). The incidence rate of infection (regional and systemic) of the PORT group was significantly lower than those of the other two groups (both P < 0.05). The satisfaction score during chemotherapy of the PORT group was (5.6 +/- 1.6), significantly higher than those of the PICC and CVC groups [(3.3 +/- 0.8) and (3.9 +/- 0.6) respectively, both P < 0.05], and the satisfaction score between chemotherapy courses of the PORT group was (5.7 +/- 0.7), significantly higher than those of the PICC and CVC groups [(4.5 +/- 0.8) and (4.8 +/- 1.2) respectively, both P < 0.05].
  
  
  CONCLUSIONS
  The technology of central vein catheter indwelling with subcutaneous port in patients undergoing chemotherapy is effective and safe.
authors.affiliation: Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Ge
authors.forename: Jing
authors.initials: J
authors.lastname: Cang
authors.forename: Zhang-gang
authors.initials: ZG
authors.lastname: Xue
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002405:Catheterization, Central Venous / Q000379:methods*; D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents