title: Synthetic approaches to the 2007 new drugs.
abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 19 NCEs marketed in 2007.
authors.affiliation: Pfizer Inc, La Jolla, CA 92037, USA.
authors.forename: Kevin K-C
authors.initials: KK
authors.lastname: Liu
authors.forename: Subas M
authors.initials: SM
authors.lastname: Sakya
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: O'Donnell
authors.forename: Jin
authors.initials: J
authors.lastname: Li
mesh_terms: D015195:Drug Design; D006801:Humans; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013997:Time Factors
chemical_list: D004364:Pharmaceutical Preparations