title: Transition zone index and bothersomeness of voiding symptoms as predictors of early unfavorable outcomes after transurethral resection of prostate.
abstract: BACKGROUND
  The objective of this study was to establish the influence of preoperative parameters on unfavorable outcomes after transurethral resection of the prostate.
  
  
  METHODS
  In a prospective study, 90 patients underwent transurethral resection of the prostate. The standardized protocol was used to investigate parameters, preoperatively and after 6 months. The baseline values were analyzed with respect to the probability of predicting the effectiveness of the outcome.
  
  
  RESULTS
  All preoperative parameters changed significantly, from 55.1 to 116% (p < 0.001). Treatment was effective for 85.6% of the patients, and the outcomes were unfavorable for 14.4%. The monovariate analysis detected the transition zone index (cut-off 0.48, p = 0.002, OR 7.48) as independent predictor of ineffective outcome. Logistic regression analysis found two the most important parameters - transition zone index (OR 30.26, p = 0.002) and bothersomeness of voiding symptoms (OR 20.7, p = 0.008) for unfavorable outcomes.
  
  
  CONCLUSIONS
  The parameters that are traditionally used cannot predict unfavorable outcomes. The transition zone index and bothersomeness of voiding symptoms are most important parameters for predicting an unfavorable outcome after TURP.
authors.affiliation: Department of Urology, Kaunas University of Medicine, Kaunas, Lithuania. daimantasmilonas@yahoo.com
authors.forename: Daimantas
authors.initials: D
authors.lastname: Milonas
authors.forename: Viktoras
authors.initials: V
authors.lastname: Saferis
authors.forename: Mindaugas
authors.initials: M
authors.lastname: Jievaltas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology* / Q000601:surgery*; D017430:Prostate-Specific Antigen / Q000378:metabolism; D011470:Prostatic Hyperplasia / Q000473:pathology*; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D020728:Transurethral Resection of Prostate / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome; D014554:Urination
chemical_list: D017430:Prostate-Specific Antigen