title: Anaphylaxis to husband's seminal plasma and treatment by local desensitization.
abstract: Hypersensitivity to human seminal fluid is rare but can be life threatening. We report a case of IgE-mediated anaphylaxis to seminal plasma that was diagnosed by skin prick tests and successfully treated by local desensitization. A 32-year-old woman suffering from angioedema and hypotension after exposure to semen was treated with epinephrine upon admission. Skin prick tests and immunoblotting for IgE binding components showed that she was sensitized to her husband's seminal plasma. Local desensitization, which persisted for six months, was achieved by intravaginal administration of serial dilutions of her husband's seminal plasma.
authors.affiliation: Department of Medicine, School of Medicine, Jeju National University, Jeju, Korea. doc4u@hanmail.net.
authors.forename: Jaechun
authors.initials: J
authors.lastname: Lee
authors.forename: Sohyung
authors.initials: S
authors.lastname: Kim
authors.forename: Miok
authors.initials: M
authors.lastname: Kim
authors.forename: Young-Bae
authors.initials: YB
authors.lastname: Chung
authors.forename: Jung-Sik
authors.initials: JS
authors.lastname: Huh
authors.forename: Chul Min
authors.initials: CM
authors.lastname: Park
authors.forename: Keun Hwa
authors.initials: KH
authors.lastname: Lee
authors.forename: Jeong Hong
authors.initials: JH
authors.lastname: Kim