title: Sealing glass ampoules with CO2 lasers.
abstract: Glass ampoules were always sealed by melting in the presence of a flame to create closures. Some poisonous gases were generated in this sealing process that pollute the injection drug and are physically harmful. In this study, CO(2) lasers were proposed for sealing glass ampoules. Because of the clean noncontact sealing process with lasers, there was nearly no pollution of the injection drug. To study in detail the principle of this sealing process, a mathematical model was put forward, and the temperature and the thermal stress field around the ampoule's neck were calculated by ANSYS software. Through experimental study, 1 ml and 5 ml ampoules were sealed successfully by a dual-laser-beam method. The results show that a laser source is an ideal heat source for sealing glass ampoules.
authors.affiliation: Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Junke
authors.initials: J
authors.lastname: Jiao
authors.forename: Xinbing
authors.initials: X
authors.lastname: Wang
authors.forename: Wenlong
authors.initials: W
authors.lastname: Tang
mesh_terms: D002245:Carbon Dioxide / Q000737:chemistry*; D004867:Equipment Design; D005898:Glass; D006358:Hot Temperature; D007834:Lasers; D054020:Lasers, Gas; D008962:Models, Theoretical; D055095:Optics and Photonics; D013696:Temperature; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide