title: [Immunology and BCG therapeutics].
abstract: The importance in the study of bacillus of Calmette-Guérin or BCG is related to several functions derived from its influence on the immunological system, between which it is found the prevention of the dissemination of the tubercular bacillus, its utilization as immunomodulator in some oncologic illness (as vesical cancer) in order to avoid post-surgical recidiva or in some forms of immunotherapy, as the cytokine (interferon alpha and interleukin-2); in addition, BCG vaccine is supplied like an immunomodulator in treatment of melanoma. It is important to continue with the study of the BCG strains for its great utility in the treatment of various diseases, example of the previous is the Tice strain, which is used in the superficial cancer of bladder and in the production of new and more powerful vaccines for the protection of tuberculosis.
authors.affiliation: Servicio de alergia e inmunología clínica, Hospital General de México, SS.
authors.forename: Manuel Anastacio
authors.initials: MA
authors.lastname: Sánchez Olivas
authors.forename: Martha Patricia
authors.initials: MP
authors.lastname: Valencia Zavala
authors.forename: José
authors.initials: J
authors.lastname: Montes Montes
authors.forename: Jesús Alberto
authors.initials: JA
authors.lastname: Sánchez Olivas
authors.forename: Iveth
authors.initials: I
authors.lastname: Flores Méndez
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000276:immunology* / Q000627:therapeutic use*; D006801:Humans
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine