title: Random capillary blood glucose cut points for diabetes and pre-diabetes derived from community-based opportunistic screening in India.
abstract: OBJECTIVE
  To determine random capillary blood glucose (RCBG) cut points that discriminate diabetic and pre-diabetic subjects from normal individuals.
  
  
  METHODS
  RCBG was performed in 1,333 individuals randomly chosen from 63,305 individuals who had participated in an opportunistic screening program. An oral glucose tolerance test was also performed by venous plasma glucose on an autoanalyzer. RCBG cut points that discriminate diabetes, impaired glucose tolerance (IGT), and impaired fasting glucose (IFG) were determined using receiver operating characteristic curves.
  
  
  RESULTS
  Using 2-h plasma glucose >or=200 mg/dl (11.1 mmol/l) criterion, the RCBG cut point of 140 mg/dl (7.7 mmol/l) gave the highest sensitivity and specificity. For 2-h plasma glucose >or=200 mg/dl (11.1 mmol/l) and fasting plasma glucose (FPG) >or=126 mg/dl (7.0 mmol/l) criteria, either 2-h plasma glucose >or=200 mg/dl (11.1 mmol/l) or FPG >or=126 mg/dl (7.0 mmol/l) criterion, and the FPG >or=126 mg/dl (7.0 mmol/l) criterion, RCBG cut point was 143 mg/dl (7.9 mmol/l). RCBG cut points for IGT, IFG according to World Health Organization criterion, and IFG according to American Diabetes Association criterion were 119 mg/dl (6.6 mmol/l), 118 mg/dl (6.6 mmol/l), and 113 mg/dl (6.3 mmol/l), respectively.
  
  
  CONCLUSIONS
  Asian Indians with RCBG >110 mg/dl at screening can be recommended to undergo definitive testing.
authors.affiliation: Madras Diabetes Research Foundation and Dr Mohan's Diabetes Specialities Centre, World Health Organization Collaborating Centre for Noncommunicable Diseases Prevention and Control, Chennai, India.
authors.forename: Suresh
authors.initials: S
authors.lastname: Somannavar
authors.forename: Anbazhagan
authors.initials: A
authors.lastname: Ganesan
authors.forename: Mohan
authors.initials: M
authors.lastname: Deepa
authors.forename: Manjula
authors.initials: M
authors.lastname: Datta
authors.forename: Viswanathan
authors.initials: V
authors.lastname: Mohan
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D002196:Capillaries; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008403:Mass Screening / Q000379:methods; D011236:Prediabetic State / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose