A case of fever of unknown origin: (18)F-FDG-PET/CT findings in Takayasu's arteritis.
This is a case of a 54 years old woman with fever of unknown origin. Physical examination showed nothing remarkable. Chest radiographs, abdominal ultrasound examination (US) and chest-abdominal-pelvic CT, showed segmental thickening of the wall of the aorta. On admission, the C-reactive protein level and the erythrocyte sedimentation rate were elevated. (18)Fluoro-fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET/CT) showed increased uptake of the aorta wall and its main branches that could be indicative of arteritis. The temporal artery biopsy was negative for giant-cell arteritis. The patient responded well to prednisolone treatment. A second (18)F-FDG-PET/CT scan showed great improvement. (18)F-FDG-PET/CT scan early indicates arteritis of the great vessels that in this case was considered to be TA and contributes in monitoring disease activity.
Skoura
Evangelia
E
Nuclear Medicine Department, Evangelismos Hospital, 45-47, Ipsilandou street, Athens 10676, Greece. lskoura@yahoo.gr
Giannopoulou
Chariklia
C
Keramida
Georgia
G
Skilakaki
Maria
M
Datseris
Ioannis
I
D001011:Aorta / Q000000981:diagnostic imaging; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D005260:Female; D005335:Fever of Unknown Origin / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D013348:Subclavian Artery / Q000000981:diagnostic imaging; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18