[Morpho-functional changes in the spinal cord of rats after focal photothrombosis].
The aim of this study was to determine the pathomorphological and functional changes after the induced focal photothrombosis of blood vessels in the thoracic region of rat spinal cord. Neuronal damage, characteristic of ischemia, both in the focus of an experimental photothrombosis and in transitional zone, were detected together with the symptoms of motor function and pelvic organ failure. The investigated method of focal photothrombosis induction may be used for modeling of spinal cord ischemia in the development of methods for pharmacological correction and partial restoration of damaged sensomotor functions.
Pashin
S S
SS
Viktorov
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IV
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D004195:Disease Models, Animal; D008027:Light; D008297:Male; D009474:Neurons / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000098:blood supply / Q000473:pathology; D020760:Spinal Cord Ischemia / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D013927:Thrombosis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology