Cutaneous umbilical endometriosis.
A 35-year-old woman presented with a four-month history of a tender umbilical nodule that bleeds during her menstrual period. Physical examination showed a hyperpigmented umbilical nodule. A biopsy specimen showed fibrotic dermis with increased numbers of blood vessels and scattered glandular structures with areas of hemosiderin deposition consistent with a diagnosis of endometriosis. Cutaneous umbilical endometriosis is rare, with an estimated incidence of 0.5 to 1.0 percent. Although anti-gonadotropin medications, such as danazol, have been used for symptomatic control, but surgical excision is the treatment of choice owing to the possibility of malignant degeneration of cutaneous endometriosis.
Lee
Arnold
A
Department of Dermatology, New York University, USA.
Tran
Hien T
HT
Walters
Ruth F
RF
Yee
Herman
H
Rosenman
Karla
K
Sanchez
Miguel R
MR
D000328:Adult; D001706:Biopsy; D020405:Dermis / Q000098:blood supply / Q000737:chemistry / Q000473:pathology; D004715:Endometriosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D005355:Fibrosis; D006485:Hemosiderin / Q000032:analysis; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014472:Umbilicus / Q000473:pathology*
D006485:Hemosiderin