[Pseudolymphomatous facial folliculitis in a child: hypochromic appearance].
BACKGROUND
The entity called pseudolymphomatous folliculitis (PLF) is a cutaneous pseudolymphoma. We report a new case of PLF with an atypical clinical presentation.


METHODS
A 6-year-old child was examined for an asymptomatic, hypochromic lesion of the face progressing for three months. The histology showed the activated pilosebaceous units with characteristic perifollicular infiltration by T-cells associated with dendritic cells expressing CD1a and protein S100. The outcome was spontaneously favourable. All of the foregoing elements supported a diagnosis of PLF.


CONCLUSIONS
PLF is defined as a clinical-pathological entity among the cutaneous pseudolymphomas. The usual clinical aspect is that of a solitary red-to-violaceous asymptomatic nodule measuring less than 1.5cm in diameter. Histology shows follicular invasion characterized by lymphocytic infiltration into pilosebaceous units, creating architectural distortion; this infiltration is associated to perifollicular dendritic cells expressing CD1a and protein S100. We report this new case of PLF because of its peculiar clinical presentation. However, FPL remains a controversial entity, since the follicular location of the pseudolymphomatous lymphocytic infiltration seems poorly specific in facial lesions.
Bulai-Livideanu
C
C
Service de dermatologie, université Paul-Sabatier, CHU de Toulouse-Purpan, place du Dr-Baylac, 31000 Toulouse, France. livideanu.c@chu-toulouse.fr
Michel
C
C
Fricker
A
A
Schubert
B
B
Paul
C
C
D000658:Amoxicillin / Q000627:therapeutic use*; D018414:CD8-Positive T-Lymphocytes / Q000187:drug effects / Q000473:pathology; D002648:Child; D003713:Dendritic Cells / Q000276:immunology / Q000473:pathology; D018450:Disease Progression; D005499:Folliculitis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008297:Male; D019310:Pseudolymphoma / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D012871:Skin Diseases / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*
D000658:Amoxicillin