Polymer-immobilized catalyst for asymmetric hydrogenation of racemic alpha-(N-benzoyl-N-methylamino)propiophenone.
Asymmetric hydrogenation of alpha-(N-benzoyl-N-methylamino)propiophenone through dynamic kinetic resolution was performed by using a polymer-immobilized chiral diamine-ruthenium-BINAP-t-BuOK system in order to yield syn-beta-amide alcohol exclusively with nearly perfect enantioselectivity.
Chiwara
Vinia Ipai
VI
Department of Materials Science, Toyohashi University of Technology, Tempaku-cho, Toyohashi 441-8580, Japan.
Haraguchi
Naoki
N
Itsuno
Shinichi
S
D002384:Catalysis; D003959:Diamines / Q000737:chemistry; D006865:Hydrogenation; D007700:Kinetics; D008024:Ligands; D011108:Polymers / Q000737:chemistry*; D011427:Propiophenones / Q000737:chemistry*; D013237:Stereoisomerism
D003959:Diamines; D008024:Ligands; D011108:Polymers; D011427:Propiophenones