Nephropathia epidemica with a 6-week incubation period after occupational exposure to Puumala hantavirus.
Serological and molecular evidence showed that a German female student became infected by Puumala hantavirus during mice trapping efforts in Finland. The incubation period before exhibiting clinical signs of nephropathia epidemica was as long as 6 weeks. Phylogenetic analysis of PUUV nucleic acid sequences amplified from the patient demonstrate that she was infected by the PUUV strain circulating at the place of her occupational exposure in Finland.
Kramski
Marit
M
Robert Koch Institute, Nordufer 20, D-13353 Berlin, Germany.
Achazi
Katharina
K
Klempa
Boris
B
Krüger
Detlev H
DH
D000328:Adult; D000818:Animals; D005260:Female; D005387:Finland; D006480:Hemorrhagic Fever with Renal Syndrome / Q000503:physiopathology / Q000821:virology*; D006801:Humans; D055256:Infectious Disease Incubation Period; D051379:Mice; D008969:Molecular Sequence Data; D016273:Occupational Exposure; D010802:Phylogeny; D029262:Puumala virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA
D012367:RNA, Viral