Effects of a ferment soy product on the adipocyte area reduction and dyslipidemia control in hypercholesterolemic adult male rats.
BACKGROUND
Available data on the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on circulating lipids and adiposity are not completely settled. This study aimed to observe the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on central obesity and dyslipidemia control in Wistar adult male rats.


METHODS
Over a period of 8 weeks, animals had "ad libitum" food intake and water consumption as well as body weight and food consumption was monitored. The animals were assigned to four different experimental groups: Control Group (C); Control + Fermented Product Group (CPF); Hypercholesterolemic diet group (H); and Hypercholesterolemic + Fermented Product Group (HPF). The HPF and CPF groups received an intragastric administration of 1 ml of fermented product daily. After the experimental period the animals were killed by decapitation, blood was collected to measure cholesterol, triglycerides and HDL-cholesterol plasma concentration. Adipocyte circumference, lipolysis and lipogenis rates were measures using epididymal and retroperitoneal white adipose tissues.


RESULTS
The results demonstrated that 1 ml/day/rat of the fermented soy product promoted important benefits such as reduced cholesterolemia in hypercholesterolemic diet group and the adipocyte circumference in both control and hypercholesterolemic diet group.


CONCLUSIONS
The fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti decreased circulating lipids levels and reduced adipocyte area in rats.
Cheik
Nadia Carla
NC
UFU/Federal University of Uberlândia, Uberlândia, Minas Gerais, Brasil. nadiacheik@terra.com.br
Rossi
Elizeu Antônio
EA
Guerra
Ricardo Luís Fernandes
RL
Tenório
Neuli Maria
NM
Oller do Nascimento
Cláudia Maria
CM
Viana
Fabiana Pavan
FP
Manzoni
Marla Simone Jovenasso
MS
Carlos
Iracilda Zeponni
IZ
Leão da Silva
Patrícia
P
Vendramini
Regina Célia
RC
Dâmaso
Ana Raimunda
AR
D017667:Adipocytes / Q000473:pathology*; D000818:Animals; D001835:Body Weight; D016984:Enterococcus faecium; D005285:Fermentation; D006937:Hypercholesterolemia / Q000178:diet therapy*; D007778:Lactobacillus; D008066:Lipolysis; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D045730:Soy Foods