title: Stenotrophomonas maltophilia infections of intact skin: a systematic review of the literature.
abstract: To highlight the importance of intact skin infection syndromes caused by Stenotrophomonas maltophilia, we review 17 reported cases. Skin infection syndrome presentations included metastatic cellulitis (58%), primary cellulitis (23%), and ecthyma gangrenosum (17%). Associated risk factors were hematologic malignancies and chemotherapy (94%), neutropenia (94%), presence of central venous catheter (17%), and exposure to broad-spectrum antibiotics (84%). The diagnosis was supported by cultures of skin biopsy specimens (35%), blood cultures (24%), or both (41%). Trimethoprim-sulfamethoxazole was the treatment of choice (76%), and outcomes were favorable (71%).
authors.affiliation: Department of Medicine, King Fahd Medical City, Riyadh, Saudi Arabia.
authors.forename: Aref A
authors.initials: AA
authors.lastname: Bin Abdulhak
authors.forename: Valerie
authors.initials: V
authors.lastname: Zimmerman
authors.forename: Bassim T
authors.initials: BT
authors.lastname: Al Beirouti
authors.forename: Larry M
authors.initials: LM
authors.lastname: Baddour
authors.forename: Imad M
authors.initials: IM
authors.lastname: Tleyjeh
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D015662:Trimethoprim, Sulfamethoxazole Drug Combination