Ceramicines B-D, new antiplasmodial limonoids from Chisocheton ceramicus.
Three new limonoids, ceramicines B-D (1-3), have been isolated from the bark of Chisocheton ceramicus. Structures and stereochemistry of 1-3 were fully elucidated and characterized by 2D NMR analysis. Ceramicines exhibited a moderate antiplasmodial activity.
Mohamad
Khalit
K
Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa, Tokyo 142-8501, Japan.
Hirasawa
Yusuke
Y
Litaudon
Marc
M
Awang
Khalijah
K
Hadi
A Hamid A
AH
Takeya
Koichi
K
Ekasari
Wiwied
W
Widyawaruyanti
Aty
A
Zaini
Noor Cholies
NC
Morita
Hiroshi
H
D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000302:isolation & purification*; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D024301:Plant Bark / Q000737:chemistry*; D010961:Plasmodium / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000981:Antiprotozoal Agents; D036701:Limonins