title: Potential oxidative stress of gold nanoparticles by induced-NO releasing in serum.
abstract: Nitric oxide (NO)-release in blood serum initiated by gold nanoparticles has been prove to be a reaction between RSNO and the gold nanoparitcles. In this reaction the NO production was catalyzed on the surface of the nanoparticles, and a new bond of Au-thiolate was simultaneously formed.
authors.affiliation: State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
authors.forename: Hong Ying
authors.initials: HY
authors.lastname: Jia
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Xue Ji
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Lu
authors.initials: L
authors.lastname: Han
authors.forename: Li Bo
authors.initials: LB
authors.lastname: Du
authors.forename: Qiu
authors.initials: Q
authors.lastname: Tian
authors.forename: Yuan Chao
authors.initials: YC
authors.lastname: Xu
mesh_terms: D015374:Biosensing Techniques; D003545:Cysteine / Q000031:analogs & derivatives / Q000097:blood; D006046:Gold / Q000494:pharmacology*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D009569:Nitric Oxide / Q000097:blood*; D009603:Nitroso Compounds / Q000097:blood; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000097:blood; D026422:S-Nitrosoglutathione / Q000097:blood; D026403:S-Nitrosothiols / Q000097:blood; D012710:Serum Albumin, Bovine
chemical_list: D009603:Nitroso Compounds; D017382:Reactive Oxygen Species; D026403:S-Nitrosothiols; C091665:S-nitrosoalbumin; D012710:Serum Albumin, Bovine; D009569:Nitric Oxide; D026422:S-Nitrosoglutathione; D006046:Gold; C021315:S-nitrosocysteine; D003545:Cysteine