Triterpene glycosides from Antarctic sea cucumbers. 2. Structure of Achlioniceosides A(1), A(2), and A(3) from the sea cucumber Achlionice violaecuspidata (=Rhipidothuria racowitzai).
Three new triterpene glycosides, achlioniceosides A(1) (1), A(2) (2), and A(3) (3), have been isolated from the Antarctic sea cucumber Achlionice violaecuspidata. The glycoside structures were elucidated using extensive NMR spectroscopic analysis including one-dimensional (1)H and (13)C spectra, (1)H-(1)H-COSY, HMBC, HMQC, and NOESY and mass spectrometry. Gycosides 1-3 are disulfated pentaosides that are branched at the first xylose residue. The sulfates are attached to C-6 of the glucose residues. Glycosides 1-3 are the first triterpene glycosides isolated from a sea cucumber belonging to the order Elasipodida.
Antonov
Alexandr S
AS
Pacific Institute of Bioorganic Chemistry of the Far East Division of the Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022, Vladivostok, Russian Federation.
Avilov
Sergey A
SA
Kalinovsky
Anatoly I
AI
Anastyuk
Stanislav D
SD
Dmitrenok
Pavel S
PS
Kalinin
Vladimir I
VI
Taboada
Sergi
S
Bosh
Aina
A
Avila
Conxita
C
Stonik
Valentin A
VA
D000818:Animals; D000864:Antarctic Regions; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012616:Sea Cucumbers / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes; C535041:achlioniceoside A(1); C535042:achlioniceoside A(2); C535043:achlioniceoside A(3)