Suppression of human immunodeficiency virus type 1 viral load during acute measles.
Acute measles virus infection can result in a transient decrease in plasma human immunodeficiency virus type 1 (HIV-1) RNA loads. We report the kinetics of plasma HIV-1 RNA loads in 2 Zambian children with confirmed and probable measles, and show that the decline in viral load is of similar magnitude to the first-phase decay rate after initiation of antiretroviral therapy.
Moss
William J
WJ
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD. wmoss@jhsph.edu.
Scott
Susana
S
Ndhlovu
Zaza
Z
Monze
Mwaka
M
Cutts
Felicity T
FT
Quinn
Thomas C
TC
Griffin
Diane E
DE
D000208:Acute Disease; D005260:Female; D015658:HIV Infections / Q000276:immunology / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000254:growth & development*; D006801:Humans; D007223:Infant; D008457:Measles / Q000276:immunology / Q000821:virology*; D008458:Measles Vaccine / Q000008:administration & dosage / Q000276:immunology; D008459:Measles virus / Q000254:growth & development* / Q000276:immunology; D012367:RNA, Viral / Q000097:blood; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019562:Viral Load; D015024:Zambia
D008458:Measles Vaccine; D012367:RNA, Viral