title: Diagnosis and Treatment of Chronic Immune-mediated Neuropathies.
abstract: The chronic autoimmune neuropathies are a diverse group of disorders, whose diagnosis and classification is based on the clinical presentations and results of ancillary tests. In chronic inflammatory demyelinating polyneuropathy, controlled therapeutic trials demonstrated efficacy for intravenous gamma-globulins, corticosteroids, and plasmaphereis. In multifocal motor neuropathy, intravenous gamma-globulins have been shown to be effective. In the other immune-mediated neuropathies, there are no reported controlled therapeutic trials, but efficacy has been reported for some treatments in non-controlled trials on case studies. Choice of therapy in individual cases is based on reported efficacy, as well as severity, progression, coexisting illness, predisposition to developing complications, and potential drug interactions.
authors.affiliation: Weill Medical College of Cornell University, NY
authors.forename: Norman
authors.initials: N
authors.lastname: Latov
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Gorson
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Brannagan
authors.forename: Roy L
authors.initials: RL
authors.lastname: Freeman
authors.forename: Slobodan
authors.initials: S
authors.lastname: Apostolski
authors.forename: Alan R
authors.initials: AR
authors.lastname: Berger
authors.forename: Walter G
authors.initials: WG
authors.lastname: Bradley
authors.forename: Chiara
authors.initials: C
authors.lastname: Briani
authors.forename: Vera
authors.initials: V
authors.lastname: Bril
authors.forename: Neil A
authors.initials: NA
authors.lastname: Busis
authors.forename: Didier P
authors.initials: DP
authors.lastname: Cros
authors.forename: Marinos C
authors.initials: MC
authors.lastname: Dalakas
authors.forename: Peter D
authors.initials: PD
authors.lastname: Donofrio
authors.forename: P James B
authors.initials: PJ
authors.lastname: Dyck
authors.forename: John D
authors.initials: JD
authors.lastname: England
authors.forename: Morris A
authors.initials: MA
authors.lastname: Fisher
authors.forename: David N
authors.initials: DN
authors.lastname: Herrmann
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Menkes
authors.forename: Zarife
authors.initials: Z
authors.lastname: Sahenk
authors.forename: Howard W
authors.initials: HW
authors.lastname: Sander
authors.forename: William J
authors.initials: WJ
authors.lastname: Triggs
authors.forename: Jean Michel
authors.initials: JM
authors.lastname: Vallat