The recent decline in mortality from Hodgkin lymphomas in central and eastern Europe.
BACKGROUND
Hodgkin lymphoma (HL) is a largely curable disease and its mortality had steadily declined in western Europe since the late 1960s. Only modest declines were, however, observed in central/eastern Europe.


METHODS
We updated trends in mortality from HL in various European areas up to 2004 and analyzed patterns in incidence for selected European countries providing national data.


RESULTS
In most western European countries, HL mortality continued to steadily decline up to the mid 2000s. More recent reductions were also observed in eastern European countries. Overall, mortality from HL declined from 1.17/100,000 (age-standardized, world population) in 1980-1989 to 1.42/100,000 in 2000-2004 in men from the 15 member states of the European Union (EU) from western and northern Europe. In the EU 10 accession countries of central and eastern Europe, male mortality from HL was 1.42/100,000 in 1980-1984, 1.32 in 1990-1994, and declined to 0.76 in 2000-2004. Similar trends were observed in women. No consistent patterns were found for HL incidence.


CONCLUSIONS
The present work confirms the persistent declines in HL mortality in western European countries, and shows favorable patterns over more recent calendar years in central/eastern ones, where rates, however, are still at levels observed in western Europe in the early 1990s.
Bosetti
C
C
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy. bosetti@marionegri.it
Levi
F
F
Ferlay
J
J
Lucchini
F
F
Negri
E
E
La Vecchia
C
C
D005060:Europe / Q000453:epidemiology; D005260:Female; D006689:Hodgkin Disease / Q000401:mortality*; D006801:Humans; D008297:Male; D009026:Mortality / Q000639:trends