The effect of 3-pentadecylphenol on DPPC bilayers ATR-IR and 31P NMR studies.
The influence of 3-pentadecylphenol (PDP) on the structure and physicochemical properties of the lipid bilayers of DPPC liposomes was studied using ATR-IR and (31)P NMR methods. On the basis of analysis of the bands assigned to the CH(2) stretching, CH(2) scissoring, C=O stretching, and PO(2)(-) stretching vibrations it was revealed that PDP influences both the hydrophobic and hydrophilic parts of the DPPC liposome bilayer. Analysis of the (31)P NMR line-shape indicated a lamellar to non-lamellar phase transition in PDP-doped DPPC dispersions. It was shown that PDP/DPPC isotropic aggregates have similar nuC=O and nu(as)PO(2)(-) band positions and lower gauche populations in the hydrophobic chain region compared with the DPPC bilayer in the liquid-crystal phase.
Cieślik-Boczula
Katarzyna
K
Faculty of Chemistry, University of Wroclaw, Joliot-Currie 14, 50-383 Wrocław, Poland. kasia_cieslik0@yahoo.com
Koll
Aleksander
A
D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008051:Lipid Bilayers / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D044367:Phase Transition; D010636:Phenols / Q000737:chemistry*; D010759:Phosphorus Isotopes / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013499:Surface Properties; D014867:Water / Q000737:chemistry
D008051:Lipid Bilayers; D008081:Liposomes; D010636:Phenols; D010759:Phosphorus Isotopes; D014867:Water; D015060:1,2-Dipalmitoylphosphatidylcholine; C538777:3-pentadecylphenol