title: Bilateral iridocorneal endothelial syndrome in a young girl with Down's syndrome.
abstract: We describe the occurrence of bilateral iridocorneal endothelial (ICE) syndrome with glaucoma in a young girl with Down's syndrome. A 16-year-old girl with Down's syndrome was found to have secondary glaucoma in the right eye with features of progressive iris atrophy in both eyes. She was uncontrolled on maximum tolerable medical therapy for glaucoma. She underwent an uneventful trabeculectomy with mitomycin-C in her right eye. Scanning electron microscopy of the trabecular meshwork obtained in this case is described.
authors.affiliation: Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110 029, India gupta_v20032000@yahoo.com.
authors.forename: Viney
authors.initials: V
authors.lastname: Gupta
authors.forename: Randhir
authors.initials: R
authors.lastname: Kumar
authors.forename: Ritesh
authors.initials: R
authors.lastname: Gupta
authors.forename: Geetha
authors.initials: G
authors.lastname: Srinivasan
authors.forename: Ramanjit
authors.initials: R
authors.lastname: Sihota
mesh_terms: D000293:Adolescent; D001284:Atrophy; D003316:Corneal Diseases / Q000150:complications* / Q000175:diagnosis; D004314:Down Syndrome / Q000150:complications*; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D007839:Functional Laterality; D005901:Glaucoma / Q000209:etiology* / Q000601:surgery; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris / Q000473:pathology; D007499:Iris Diseases / Q000150:complications* / Q000175:diagnosis; D007621:Karyotyping; D008855:Microscopy, Electron, Scanning; D013577:Syndrome; D014129:Trabecular Meshwork / Q000601:surgery / Q000648:ultrastructure; D014130:Trabeculectomy