Singlet-oxygen-mediated one-pot synthesis of 3-keto-tetrahydrofurans from 2-(beta-hydroxyalkyl) furans.
Photooxygenation of 2-(beta-hydroxyalkyl) furans affords, in one synthetic operation and in high yields, 3-keto-tetrhydrofuran motifs via intramolecular Michael-type addition to the 1,4-enedione intermediate.
Tofi
Maria
M
Department of Chemistry, University of Crete, Vasilika Vouton, 71003 Iraklion, Crete, Greece.
Koltsida
Konstantina
K
Vassilikogiannakis
Georgios
G
D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015203:Reproducibility of Results; D026082:Singlet Oxygen / Q000737:chemistry*
D005663:Furans; D026082:Singlet Oxygen