[Case of intracerebral hemorrhage due to amphetamine abuse].
We report a case of intracranial hemorrhage due to amphetamine abuse in a young adult. A 34-year-old, confused woman was transferred to our emergency room with right hemiparesis and aphasia. CT at admission demonstrated intracerebral hemorrhage in the left frontal and parietal lobes, associated with subarachnoid hemorrhage. MRA shortly after admission revealed no intracerebral vascular anomaly. Cerebral angiography following admission showed irregularity of the vessel wall in the left anterior and middle cerebral arteries. Later, a toxicology screen test for urine was found to be positive for amphetamines and metamphetamines. These findings suggested that cerebral vasculitis and hypertensive surge induced by amphetamines caused intracranial and subarachnoid hemorrhage. Amphetamine abuse should always be considered as a cause of intracranial hemorrhage in young adults.
Hara
Takeshi
T
Department of Neurosurgery, Koshigaya Municipal Hospital, 10-47-1 Higashikoshigaya, Koshigaya-shi, Saitama 343-8577, Japan.
Fujii
Ryosuke
R
Ohno
Shinsuke
S
Tomita
Yoshiyuki
Y
Tsunoda
Akira
A
Maruki
Chikashi
C
Kurokawa
Shigeo
S
D000328:Adult; D000661:Amphetamine / Q000009:adverse effects*; D019969:Amphetamine-Related Disorders / Q000150:complications* / Q000175:diagnosis; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D018810:Magnetic Resonance Angiography; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000139:chemically induced
D000661:Amphetamine