Complete androgen insensitivity syndrome--a review.
This review paper highlights important diagnostic and therapeutic concerns for girls with Complete Androgen Insensitivity Syndrome (CAIS). CAIS is an androgen receptor defect disorder associated with vaginal and uterine agenesis in women with a 46,XY karyotype. The major clinical issues surrounding this syndrome include timing of gonadectomy, hormone replacement, vaginal dilation, and attention to psychological issues.
Oakes
Meghan B
MB
Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, Michigan 48109-0276, USA.
Eyvazzadeh
Aimee D
AD
Quint
Elisabeth
E
Smith
Yolanda R
YR
D013734:Androgen-Insensitivity Syndrome / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male