Congenital Rosai-Dorfman disease presenting with anemia, thrombocytopenia, and hepatomegaly.
Rosai-Dorfman disease (RDD) is a rare entity of non-Langerhans cell histiocytoses (non-LCH) which usually presents with bilateral painless cervical lymphadenopathy. We describe a neonate with RDD who presented with anemia, thrombocytopenia and hepatomegaly. He recovered spontaneously with conservative management. This represents an atypical presentation of RDD. Conservative management with close monitoring can be adopted for some with systemic involvement.
Chow
C P
CP
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong, China.
Ho
H K
HK
Chan
G C F
GC
Cheung
A N
AN
Ha
S Y
SY
D000740:Anemia / Q000150:complications*; D001706:Biopsy; D006529:Hepatomegaly / Q000150:complications / Q000473:pathology / Q000601:surgery; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000151:congenital*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013921:Thrombocytopenia / Q000150:complications*