Waste not, want not: a viral RNA degradation product modulates west nile virus pathogenesis.
In this issue of Cell Host & Microbe, Pijlman et al. define the structure and mechanism of generation of a small viral noncoding RNA present in flavivirus-infected cells that has a marked impact on the fate of infected cells and virulence in vivo.
Pierson
Theodore C
TC
Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
D006801:Humans; D022661:RNA, Untranslated / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism*; D014774:Virulence; D014902:West Nile virus / Q000472:pathogenicity*
D022661:RNA, Untranslated; D012367:RNA, Viral