title: Stimulating conversations between HP1a and histone demethylase dKDM4A.
abstract: An interaction between Drosophila HP1a and H3K36 histone demethylase dKDM4A reported in this issue of Molecular Cell (Lin et al., 2008) offers an explanation for association of HP1a with active genes, reinforcing the notion of dynamic interplay among epigenetic marks on histone tails during transcription.
authors.affiliation: Department of Biochemistry, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Lori L
authors.initials: LL
authors.lastname: Wallrath
authors.forename: Sarah C R
authors.initials: SC
authors.lastname: Elgin
mesh_terms: D000818:Animals; D000090266:Chromobox Protein Homolog 5; D002868:Chromosomal Proteins, Non-Histone / Q000737:chemistry / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000166:cytology / Q000201:enzymology*; D006657:Histones / Q000378:metabolism; D008239:Lysine / Q000378:metabolism; D008745:Methylation; D008954:Models, Biological; D010089:Oxidoreductases, N-Demethylating / Q000737:chemistry / Q000378:metabolism*; D017434:Protein Structure, Tertiary
chemical_list: D002868:Chromosomal Proteins, Non-Histone; D006657:Histones; D000090266:Chromobox Protein Homolog 5; D010089:Oxidoreductases, N-Demethylating; D008239:Lysine