From kinase to cyclase: an unusual example of catalytic promiscuity modulated by metal switching.
Sánchez-Moreno
Israel
I
Departamento de Química Orgánica Biológica, Instituto de Química Orgánica General, CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
Iturrate
Laura
L
Martín-Hoyos
Rocio
R
Jimeno
María Luisa
ML
Mena
Montaña
M
Bastida
Agatha
A
García-Junceda
Eduardo
E
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D055162:Biocatalysis; D016971:Citrobacter freundii / Q000201:enzymology*; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008670:Metals / Q000494:pharmacology*; D019761:Phosphorus-Oxygen Lyases / Q000378:metabolism*; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity
D008670:Metals; D005182:Flavin-Adenine Dinucleotide; D000255:Adenosine Triphosphate; D017853:Phosphotransferases (Alcohol Group Acceptor); C023132:glycerone kinase; D019761:Phosphorus-Oxygen Lyases; C111330:FMN cyclase