Copper-catalyzed 2:1 coupling reaction of arynes with alkynes.
A formal insertion reaction of two molar amounts of arynes into a C-H bond of terminal alkynes is efficaciously catalyzed by copper(I) chloride, giving 2-alkynylbiaryls in one step.
Yoshida
Hiroto
H
Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima 739-8527, Japan. yhiroto@hiroshima-u.ac.jp
Morishita
Takami
T
Nakata
Hiromi
H
Ohshita
Joji
J