[Chemotherapy indications in the treatment of metastases from urological malignancies].
Chemotherapy is useful for many metastatic urological cancer treatments. The main aim is to improve survival and quality of life. Efficacy is directly linked to the type of carcinoma and its chemosensitivity. Very efficient for testis tumors, it is at present the best weapon against metastatic urothelial tumors, especially for transitional cell carcinoma of the bladder. For prostate cancer, chemotherapy is used when metastatic adenocarcinoma has become refractory to hormonal treatment. It is not useful for renal carcinoma. New targeted therapies could soon modify the role of chemotherapy. Thus in clinical trials, some molecules are being tested alone or in association with referent chemotherapies in order to improve results.
Théodore
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Service d'Oncologie, Hôpital Foch, Suresnes, France. c.theodore@hopital-foch.org
D006801:Humans; D009362:Neoplasm Metastasis / Q000188:drug therapy; D014571:Urologic Neoplasms / Q000188:drug therapy* / Q000473:pathology*