title: Epidemiology of hepatitis B virus in Bangladeshi general population.
abstract: BACKGROUND
  Hepatitis B virus (HBV) is encountered sporadically the year round in Bangladesh. It results in a wide range of liver diseases, with asymptomatic acute hepatitis at one end to hepatocellular carcinoma (HCC) at the other end of the spectrum.
  
  
  METHODS
  All 1018 individuals of different age groups and sex with varied religious, educational and social backgrounds were tested for HBsAg by ELISA. The positive samples were further tested by ELISA for HBeAg. Before testing, blood samples were preserved at -20 degree centigrade. The study was conducted in a semi-urban location on the outskirts of Dhaka.
  
  
  RESULTS
  Of the 1018 individuals, 5.5% tested positive for HBsAg. None were tested positive for anti-HCV. Among the HBsAg-positive population, 58.93% were HBeAg-positive and the rest 41.07% HBeAg-negative. There was a male predominance and those who were tested positive were mostly between 16 and 50 years of age. Major risk factors for exposure to HBV appeared to be injudicious use of injectable medications, treatment by unqualified, traditional practitioners, mass-vaccination against cholera and smallpox, barbers and body piercing.
  
  
  CONCLUSIONS
  HBV remains a major cause of morbidity and mortality in Bangladesh and we have a long way to go before we may bid farewell to this deadly menace.
authors.affiliation: Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. shwapnil@agni.com
authors.forename: Mamun-Al
authors.initials: MA
authors.lastname: Mahtab
authors.forename: Salimur
authors.initials: S
authors.lastname: Rahman
authors.forename: Md Fazal
authors.initials: MF
authors.lastname: Karim
authors.forename: Mobin
authors.initials: M
authors.lastname: Khan
authors.forename: Graham
authors.initials: G
authors.lastname: Foster
authors.forename: Susannah
authors.initials: S
authors.lastname: Solaiman
authors.forename: Shahrin
authors.initials: S
authors.lastname: Afroz
mesh_terms: D000208:Acute Disease; D000328:Adult; D017677:Age Distribution; D001459:Bangladesh / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D019694:Hepatitis B, Chronic / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D011795:Surveys and Questionnaires; D055815:Young Adult