Diffuse large B-cell lymphoma with Homer-Wright rosettes, sinusoidal growth pattern, and CD30 expression: a possible overlap between microvillous lymphomas and sinusoidal CD30-positive large B-cell lymphomas.
Rosette formation is an unusual finding in malignant lymphomas. We herein report another case of a diffuse large B-cell lymphoma (DLBCL) with ultrastructural evidence of cellular projections, sinusoidal growth pattern, and strong CD30 expression. A literature review of the DLBCL cases showing all these features was also performed.
Goteri
Gaia
G
Anatomic Pathology, Polytechnic University of Marche, Ancona Hospital, Via Conca 71, 60020 Torrette di Ancona (AN), Italy. g.goteri@univpm.it
Costagliola
Antonello
A
Tassetti
Angela
A
Stramazzotti
Daniela
D
Morroni
Manrico
M
Rupoli
Serena
S
Centurioni
Riccardo
R
Leoni
Pietro
P
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism* / Q000648:ultrastructure*; D046529:Microscopy, Electron, Transmission
D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen