title: Protein-losing enteropathy in a case of nodal follicular lymphoma without a gastrointestinal mucosal lesion.
abstract: Protein-losing enteropathy (PLE) is characterized by gastrointestinal loss of serum protein. It is usually caused by hypersecretion from a tumor, ulcer, or long standing lymphangiectasia. However, we report a 47-year-old man of peritoneal nodal follicular lymphoma who developed PLE with none of them. Oozing of whitish fluid from duodenal bulbar mucosa was endoscopically seen, resulting in continuous loss of protein. Chemotherapy was effective and PLE was rapidly diminished. Nodal lymphoma lesion was considered to disturb lymphatic flow and to regurgitate it to duodenal mucosa. To our knowledge, this is the second report of a lymphoma patient presenting PLE without a gastrointestinal mucosal lesion.
authors.affiliation: Department of Hematology, Aiseikai-Yamashina Hospital, Kyoto. hp@aiseikaihp.or.jp
authors.forename: Hiroto
authors.initials: H
authors.lastname: Kaneko
authors.forename: Mihoko
authors.initials: M
authors.lastname: Yamashita
authors.forename: Muneo
authors.initials: M
authors.lastname: Ohshiro
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ohkawara
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nomura
authors.forename: Shigeo
authors.initials: S
authors.lastname: Horiike
authors.forename: Shouhei
authors.initials: S
authors.lastname: Yokota
authors.forename: Masafumi
authors.initials: M
authors.lastname: Taniwaki
mesh_terms: D005753:Gastric Mucosa / Q000473:pathology*; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008224:Lymphoma, Follicular / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011504:Protein-Losing Enteropathies / Q000150:complications / Q000175:diagnosis* / Q000473:pathology