[Specular microscopy and pseudoexfoliative syndrome].
Focal production of pseudoexfoliative material is a stress to the endothelial cells, leading to a secondary degeneration and corneal decompensation. This typically occurs as a bilateral, asymmetrical, slowly progressive corneal endotheliopathy, more frequent in women, after the seventh decade of age. A severe decrease of endothelial cell density occurs--shown by specular microscopy. A persistent high level of the intraocular pressure and the metabolic disturbance in glaucoma affect the endothelium function. A severe decrease of the endothelial cell density occurs (up to 35%) in pseudoexfoliative keratopathy were glaucoma is associated.
Tebeanu
Eliza
E
Spitalul clinic de urgenţă Militar Central "Dr. Carol Davila", Bucureşti. elizatebeanu@yahoo.com
Stefan
C
C
D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D004728:Endothelium, Corneal / Q000473:pathology*; D017889:Exfoliation Syndrome / Q000150:complications / Q000473:pathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000209:etiology / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008853:Microscopy / Q000379:methods*; D008875:Middle Aged; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D014792:Visual Acuity