title: Galerkin-based meshless methods for photon transport in the biological tissue.
abstract: As an important small animal imaging technique, optical imaging has attracted increasing attention in recent years. However, the photon propagation process is extremely complicated for highly scattering property of the biological tissue. Furthermore, the light transport simulation in tissue has a significant influence on inverse source reconstruction. In this contribution, we present two Galerkin-based meshless methods (GBMM) to determine the light exitance on the surface of the diffusive tissue. The two methods are both based on moving least squares (MLS) approximation which requires only a series of nodes in the region of interest, so complicated meshing task can be avoided compared with the finite element method (FEM). Moreover, MLS shape functions are further modified to satisfy the delta function property in one method, which can simplify the processing of boundary conditions in comparison with the other. Finally, the performance of the proposed methods is demonstrated with numerical and physical phantom experiments.
authors.affiliation: Key Laboratory of Complex Systems and Intelligence Science, Institute of Automation, Chinese Academy of Sciences, P. O. Box 2728, Beijing, 100190, China. tian@ieee.org
authors.forename: Chenghu
authors.initials: C
authors.lastname: Qin
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
authors.forename: Xin
authors.initials: X
authors.lastname: Yang
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.forename: Guorui
authors.initials: G
authors.lastname: Yan
authors.forename: Jinchao
authors.initials: J
authors.lastname: Feng
authors.forename: Yujie
authors.initials: Y
authors.lastname: Lv
authors.forename: Min
authors.initials: M
authors.lastname: Xu
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D008027:Light; D008954:Models, Biological; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D017785:Photons; D012542:Scattering, Radiation