title: Case report of mastocytosis in an adult.
abstract: A case of adult-onset mastocytosis is presented to illustrate the classification, signs, symptoms, workup, treatment, and prognosis for this unusual condition. Although there is no cure for mastocytosis, symptoms of histamine release can be minimized with oral antihistamines. Ongoing surveillance of organ systems affected remains important. Our patient's mast cell disease predisposed him to bone loss, but there was no evidence of disease beyond the skin. He has done well with continued follow up monitoring his serum tryptase and oral antihistamine treatment.
authors.affiliation: Department of Internal Medicine, Division of General Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
authors.forename: Allison
authors.initials: A
authors.lastname: Barker
authors.forename: Rosalyn W
authors.initials: RW
authors.lastname: Stewart
mesh_terms: D000284:Administration, Oral; D017668:Age of Onset; D015415:Biomarkers / Q000097:blood; D001851:Bone Diseases, Metabolic / Q000150:complications; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008415:Mastocytosis / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D034701:Mastocytosis, Cutaneous / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D053802:Tryptases / Q000097:blood
chemical_list: D015415:Biomarkers; D006633:Histamine Antagonists; D053802:Tryptases