[Relationship between antioxidant activities and contents of active ingredients in Radix Scutellaria].
OBJECTIVE
To study the relationship between the antioxidant activities and the contents of active ingredients in Radix Scutellaria.


METHODS
The antioxidant activities of extracts and active ingredients of Radix Scutellaria in NADPH-dependent lipid peroxidation in rat liver microsome were assayed.


RESULTS
Extracts of Radix Scutellaria showed a 50% inhibition of lipid peroxidation in the concentration range of 2.72-18.27 mg x L(-1).


CONCLUSIONS
The antioxidant activities of extracts of Radix Scutellaria are not only related with the contents but also the ratio of the active ingredients.
Yang
Bin
B
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ybinmm@hotmail.com
Liang
Ri-xin
RX
Zhou
Xiao-ning
XN
Gao
Wei
W
Huang
Lu-qi
LQ
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D031363:Scutellaria / Q000737:chemistry*
D000975:Antioxidants; D004365:Drugs, Chinese Herbal