[Estimation of serum C-reactive protein values in patients with pulmonary tuberculosis].
Two hundred and forty-three patients with different forms of active pulmonary tuberculosis were examined. The level of C-reactive protein (CRP) was determined by immunoturbidimetry. Its normal values were taken to be 0-3 mg/l. The increased CRP levels revealed in 80.7% of the patients formed two peaks in the ranges of 4-5 (25.1%) and 21-100 (28.9%) mg/l. The higher values of CRP with the maximum of 239 mg/l were found in 11.1% of patients. The values of CRP clearly correlated with the degree of intoxication, the presence and rate of bacterial discharge, the extent of the process, the absence or presence of decay. By the end of an intensive phase of chemotherapy (3 months) in case of its efficiency, the level of CRP significantly decreased, tending to the upper subclinical range (12.1 +/- 1.9 mg/l) whereas in ineffective treatment it substantially unchanged.
Kaminskaia
G O
GO
Abdullaev
R Iu
RIu
Komissarova
O G
OG
D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D018450:Disease Progression; D006801:Humans; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D011379:Prognosis; D014397:Tuberculosis, Pulmonary / Q000097:blood* / Q000188:drug therapy; D055815:Young Adult
D000995:Antitubercular Agents; D015415:Biomarkers; D002097:C-Reactive Protein