Scanning your body is different from performing body movements: a double dissociation between body representational neglect and apraxia.
Body representational neglect (BRN) and apraxia can be found after left hemisphere (LH) lesions. Additionally, both disorders recruit knowledge about certain body parts, their position in space, and their spatial relationship to each other. Hence, the present study examined whether BRN and apraxia can be functionally dissociated at the behavioral and neural level. 23 LH lesioned patients were examined with a standardized body neglect test (Vest test) and a standardized test of apraxia (imitation of meaningless gestures). At the behavioral level BRN and apraxia showed a double dissociation. Moreover, these deficits were associated with specific brain lesions: while BRN was related to lesions in Brodmann areas 6 and 44 and frontal white matter, apraxia was linked to lesions in the superior longitudinal fasciculus and parietal and central white matter. The results are discussed as indicating dissociable representations of the human body within the left cerebral hemisphere.
Groh-Bordin
Christian
C
Clinical Neuropsychology Unit, Saarland University, Saarbruecken, Germany. c.groh@mx.uni-saarland.de
Glocker
Daniela
D
Bittl
Petra
P
Keller
Ingo
I
Preger
Rudolf
R
Hildebrandt
Helmut
H
Kerkhoff
Georg
G
D000328:Adult; D000368:Aged; D001072:Apraxias / Q000473:pathology / Q000503:physiopathology*; D001828:Body Image; D001930:Brain Injuries / Q000473:pathology / Q000503:physiopathology; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D005868:Gestures; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000502:physiology*; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000473:pathology / Q000503:physiopathology*; D011594:Psychometrics