title: Bilateral persistent hyperplastic primary vitreous.
abstract: A case of bilateral persistent hyperplastic primary vitreous (PHPV) in a 3-month-old male infant, who had bilateral leukokoria, is presented. The child was referred for imaging with a clinical suspicion of retinoblastoma. Gray-scale ultrasound evaluation revealed an echogenic band in the posterior segment of both globes, extending from the posterior surface of the lens capsule to the optic disc. Doppler examination revealed the presence of arterial flow in the band in both globes. Associated echogenic hemorrhage was also seen, which was confirmed by computed tomography. Most cases of PHPV are sporadic and unilateral, and bilateral PHPV is rare. The imaging features in this case suggest the diagnosis of bilateral PHPV and differentiate it from retinoblastoma. This entity, although infrequent, should be considered in the differential diagnosis while evaluating bilateral leukokoria.
authors.affiliation: Department of Radiology, Getwell Polyclinic and Hospital, Jaipur - 302 004, India. drtjain@yahoo.com
authors.forename: Tarun P
authors.initials: TP
authors.lastname: Jain
mesh_terms: D003937:Diagnosis, Differential; D007839:Functional Laterality; D006801:Humans; D007223:Infant; D008297:Male; D054514:Persistent Hyperplastic Primary Vitreous / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color; D014822:Vitreous Body / Q000098:blood supply; D014823:Vitreous Hemorrhage / Q000000981:diagnostic imaging