title: Intracranial hypertension in pediatric patients with acute lymphoblastic leukemia.
abstract: Acute lymphoblastic leukemia (ALL) remains one of the most common malignancies of childhood. Between April 1999 and August 2004, 9 of 207 patients treated at a Tertiary Oncology Service for ALL presented with Intracranial Hypertension (IH). Seven of the patients met the diagnostic criteria for Idiopathic Intracranial Hypertension (IIH). Four of the patients were treated with cerebrospinal fluid (CSF) drainage alone and four required Acetazolamide. Two of the four patients who were treated with Acetazolamide required subsequently a lumbar-peritoneal (LP) shunt. One patient succumbed to his disease before receiving any specific treatment.
authors.affiliation: Department of Pediatric Neurology, St George's Hospital, London, UK.
authors.forename: George
authors.initials: G
authors.lastname: Vartzelis
authors.forename: Donna
authors.initials: D
authors.lastname: Lancaster
authors.forename: Penny
authors.initials: P
authors.lastname: Fallon
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000188:drug therapy; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy
chemical_list: D000086:Acetazolamide