title: [Pain and bone metastases].
abstract: Average 20% of the cancer patients will have bone metastasis most of time painful and with variable clinical expressions. Due to animal models, the bone metastasis pain is better known and it explains the different treatments mechanisms. After a suitable evaluation of the pain, several therapeutic approaches can be suggested. In addition to the classical analgesics, several medications are known to be efficient in few indications like neuropathic pain. Besides a local surgery, an external radiotherapy or an interventional radiology treatment can often be useful along with a medical treatment. When there is a bone progression, the anti-cancer treatment by chemotherapy, hormonotherapy or targeted therapies must always be reviewed, because if efficient it could have an analgesic action.
authors.affiliation: Service de Médecine B, Centre René Huguenin, 35 Rue Dailly, 92210 Saint Cloud, France.
authors.forename: J
authors.initials: J
authors.lastname: Wassermann
authors.forename: B
authors.initials: B
authors.lastname: De La Lande
authors.forename: A
authors.initials: A
authors.lastname: Pecking
authors.forename: L
authors.initials: L
authors.lastname: Brasseur
mesh_terms: D001859:Bone Neoplasms / Q000150:complications* / Q000556:secondary* / Q000628:therapy; D003663:Decision Trees; D006801:Humans; D010146:Pain / Q000175:diagnosis / Q000209:etiology*; D059408:Pain Management; D010147:Pain Measurement; D011795:Surveys and Questionnaires