title: [Fetal bone and joint disorders].
abstract: The article discusses the physiology and pathology of fetal bone and joint development and functions. The bones provide static support for the body. The skull and the bones of spinal column encase the central and part of the peripheral nervous system. The ribs and the sternum shield the heart and the lungs, while the bones of the pelvis protect the intraabdominal organs. Pathological changes of these bony structures may impair the functions of the respective systems or internal organs. Movements of the bones are brought about by muscles. The deriving motions are facilitated by joints. Bony anomalies of the extremities limit their effective functions. Apart from skeletal and joint abnormalities, akinesia may also be caused by neurological, muscular and skin diseases that secondarily affect the functions of bones and joints. Such pathological changes may lead to various degrees of physical disability and even to death. Some of the mentioned anomalies are recognizable in utero by ultrasound. The diagnosis may serve as medical indication for abortion in those instances when the identified abnormality is incompatible with independent life.
authors.affiliation: Toldy Ferenc Kórház Szülészeti és Nogyógyászati Osztály Cegléd Pf. 63. 2700. jakobovits@freemail.hu
authors.forename: Akos
authors.initials: A
authors.lastname: Jakobovits
mesh_terms: D001847:Bone Diseases / Q000453:epidemiology / Q000473:pathology*; D001842:Bone and Bones / Q000002:abnormalities* / Q000196:embryology; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000473:pathology*; D005315:Fetal Diseases / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007592:Joint Diseases / Q000453:epidemiology / Q000473:pathology*; D007596:Joints / Q000002:abnormalities* / Q000196:embryology; D009436:Neural Tube Defects / Q000473:pathology; D017678:Sex Distribution; D016135:Spinal Dysraphism / Q000473:pathology; D016216:Ultrasonography, Prenatal