[Advances on progesterone receptor gene].
The steroid hormone, progesterone, plays a key role in diverse events associated with female reproduction. In humans and other vertebrates, the biological activity of progesterone is mediated by modulation of the transcriptional activity of two progesterone receptors, PGR-A and PGR-B. This review introduced the structure, expression regulation and polymorphism of progesterone receptor gene. The relationship between progesterone receptor gene and reproductive function was also discussed in mammals.
Zhang
Bao-Yun
BY
Bioengineering Institute of Chongqing University, Chongqing 400030, China. zhangbaoyun418@sina.com
DI
Ran
R
Chu
Ming-Xing
MX
Wang
Ping-Qing
PQ
Lu
Lang
L
D000818:Animals; D006801:Humans; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011980:Receptors, Progesterone / Q000235:genetics* / Q000378:metabolism; D012098:Reproduction / Q000235:genetics
D011980:Receptors, Progesterone