Late-Onset Friedreich's Ataxia Presenting as a Spastic Paraparesis.
A 55-year-old woman presented with a 10-yeai history of a progressive gait disorder. Her examination showed a spastic paraparesis with brisk deep tendon reflexes, but only minimal limb ataxia and no evidence for a sensory neuropathy The patient was found to be homozygous for the GAA trinucleotide repeal diagnostic of Friedreich's ataxia The presentation of Friedreich's ataxia as a spastic paraparesis reinforces the appreciation of the variable phenotype of this disease.
Silvers
D S
DS
From the Department of Neurology Hardford hospital and the university of connecricur school of medicinefariningtonconnecticur.
Felice
K J
KJ