Teratoid hepatoblastoma.
We present the case of a Middle Eastern child, diagnosed and treated at 8 months of age for a hepatic neuroblastoma. After surgical removal of a 7 cm mass of the left liver lobe at our institution when the child was 15 months of age, the tumor was reclassified as a teratoid hepatoblastoma. The tumor was composed of fetal and embryonal hepatic tissue, undifferentiated tissue, and a teratoid background of loose mesenchymal tissue containing osteoid, squamous, and mucinous epithelium. We speculate on the histogenesis of teratoid hepatoblastoma and discuss its association with chemotherapy.
Buccoliero
Anna Maria
AM
Department of Human Pathology and Oncology, Careggi Hospital, University of Florence, Florence, Italy. ambuccoliero@unifi.it
Castiglione
Francesca
F
Maio
Vincenza
V
Moncini
Daniela
D
Sardi
Iacopo
I
Taddei
Antonio
A
Martin
Alessandra
A
Messineo
Antonio
A
Taddei
Gian Luigi
GL
D000971:Antineoplastic Combined Chemotherapy Protocols; D018197:Hepatoblastoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D013724:Teratoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy