title: Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides.
abstract: Efficient enzymatic syntheses of isosteric phosphono analogues of sugar nucleotides have been accomplished using a thymidylyltransferase.
authors.affiliation: Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J3.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Beaton
authors.forename: Malcolm P
authors.initials: MP
authors.lastname: Huestis
authors.forename: Ali
authors.initials: A
authors.lastname: Sadeghi-Khomami
authors.forename: Neil R
authors.initials: NR
authors.lastname: Thomas
authors.forename: David L
authors.initials: DL
authors.lastname: Jakeman
mesh_terms: D055162:Biocatalysis; D002240:Carbohydrate Sequence; D007700:Kinetics; D009711:Nucleotides / Q000096:biosynthesis* / Q000737:chemistry; D009713:Nucleotidyltransferases / Q000378:metabolism*; D013403:Sugar Phosphates / Q000096:biosynthesis* / Q000737:chemistry
chemical_list: D009711:Nucleotides; D013403:Sugar Phosphates; D009713:Nucleotidyltransferases; C020587:glucose-1-phosphate thymidylyltransferase