title: Rate of inpatient weight restoration predicts outcome in anorexia nervosa.
abstract: OBJECTIVE
  To examine weight restoration parameters during inpatient treatment as predictors of outcome in anorexia nervosa (AN).
  
  
  METHODS
  Adolescent and adult females admitted for inpatient eating disorder treatment were recruited for an ongoing longitudinal study. This analysis examined several weight restoration parameters as predictors of clinical deterioration after discharge among participants with AN.
  
  
  RESULTS
  Rate of weight gain was the only restoration parameter that predicted year 1 outcome. Clinical deterioration occurred significantly less often among participants who gained >or=0.8 kg/week (12/41, 29%) than those below this threshold (20/38, 53%) (chi(2) = 4.37, df = 1, p = .037) and remained significant after adjustment for potential confounders.
  
  
  CONCLUSIONS
  Weight gain rate during inpatient treatment for AN was a significant predictor of short-term clinical outcome after discharge. It is unclear whether weight gain rate exerts a causal effect or is rather a marker for readiness to tolerate weight restoration and engage in the recovery process.
authors.affiliation: Laureate Institute for Brain Research, Tulsa, Oklahoma 74136, USA. bclund@saintfrancis.com
authors.forename: Brian C
authors.initials: BC
authors.lastname: Lund
authors.forename: Elsa R
authors.initials: ER
authors.lastname: Hernandez
authors.forename: William R
authors.initials: WR
authors.lastname: Yates
authors.forename: Jeff R
authors.initials: JR
authors.lastname: Mitchell
authors.forename: Patrick A
authors.initials: PA
authors.lastname: McKee
authors.forename: Craig L
authors.initials: CL
authors.lastname: Johnson
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000178:diet therapy / Q000523:psychology / Q000628:therapy*; D001521:Behavior Therapy; D015992:Body Mass Index; D003131:Combined Modality Therapy; D004750:Enteral Nutrition / Q000379:methods*; D005260:Female; D006801:Humans; D007297:Inpatients; D007441:Intubation, Gastrointestinal; D007902:Length of Stay; D008137:Longitudinal Studies; D008875:Middle Aged; D009042:Motivation; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011613:Psychotherapy / Q000379:methods*; D015430:Weight Gain; D055815:Young Adult