[Arterial hypertension and the kidney].
Arterial hypertension is a factor of major risk of cardiovascular complications which represent the first cause of death in the world. One can define it as a level of blood pressure (140/90 mmHg) beyond which the cardiovascular risk is important and requires a therapeutic action. One of the etiopathogenic assumptions selected is a disordered state of the relation pressure natriuresis wich is the major mechanism of control of long-term arterial pressure. The diagnostic means and of monitoring were the subject of consensus on the level of scientific societies what is not the case of the therapeutic strategy . In more of lifestyle change, the patients with renal diseases generally require an association of antihypertensive drugs whose the thiazide diuretics ones must have a leader place. Their association with ACE inhibitors or angiotensin receptor antagonists seem to give the best effectiveness in term of cardioprotection and nephroprotection.
Niang
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Service de Néphrologie, CHU A. le Dantec, BP 6548, Dakar, Senegal. niangabdou@yahoo.com
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000209:etiology*; D002986:Clinical Trials as Topic; D048909:Diabetes Complications; D004359:Drug Therapy, Combination; D015444:Exercise; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007668:Kidney / Q000503:physiopathology*; D007674:Kidney Diseases / Q000209:etiology*; D008019:Life Style; D009765:Obesity / Q000150:complications; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D051437:Renal Insufficiency / Q000209:etiology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D016540:Smoking Cessation; D049993:Sodium Chloride Symporter Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D015431:Weight Loss; D014944:World Health Organization
D000806:Angiotensin-Converting Enzyme Inhibitors; D000960:Hypolipidemic Agents; D010975:Platelet Aggregation Inhibitors; D049993:Sodium Chloride Symporter Inhibitors