Reduced 10-year risk of coronary heart disease in patients who participated in a community-based diabetes prevention program: the DEPLOY pilot study.
OBJECTIVE
We evaluated whether participation in a community-based group diabetes prevention program might lead to relative changes in composite 10-year coronary heart disease (CHD) risk for overweight adults with abnormal glucose metabolism.


METHODS
We used the UK Prospective Diabetes Study engine to estimate CHD risk for group-lifestyle and brief counseling (control) groups. Between-group risk changes after 4 and 12 months were compared using ANCOVA.


RESULTS
Baseline 10-year risk was similar between treatment groups (P = 0.667). At 4 and 12 months, the intervention group experienced significant decreases in 10-year risk from baseline (-3.28%, P < 0.001; and -2.23%, P = 0.037) compared with control subjects (-0.78%, P = 0.339; and +1.88%, P = 0.073). Between-group differences were statistically significant and increased from the 4- to 12-month visits.


CONCLUSIONS
Community-based delivery of the Diabetes Prevention Program lifestyle intervention could be a promising strategy to prevent both CHD and type 2 diabetes in adults with pre-diabetes.
Lipscomb
Elaine R
ER
Roudebush Veterans Affairs Medical Center, Health Services Research & Development Center of Excellence for Implementing Evidence-Based Practice, Indianapolis, Indiana, USA. elaine.lipscomb@va.gov
Finch
Emily A
EA
Brizendine
Edward
E
Saha
Chandan K
CK
Hays
Laura M
LM
Ackermann
Ronald T
RT
D016022:Case-Control Studies; D003327:Coronary Disease / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D050177:Overweight / Q000150:complications; D010865:Pilot Projects; D013997:Time Factors