[Plant micro RNA biogenesis].
Micro RNAs are 21-24 nt long RNA molecules involved in the regulation of gene expression on mRNA level. Mature miRNA molecules associated with the RNA-induced silencing complex (RISC) guide specifically mRNA cleavage or inhibit the translation. In plants selective mRNA degradation in miRNA-dependent pathway is a widespread mechanism that occurs more frequently than translation inhibition. miRNA precursors, known as pri-miRNA, are processed in several steps to produce mature miRNA molecules. There are several plant proteins involved in miRNA processing: DCL1, HYL1, SE, HEN1 and HASTY. The role of these proteins is discussed.
Sobkowiak
Lukasz
L
Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 5 Miedzychodzka St., 60-371 Poznan, Poland.
Szarzyńska
Bogna
B
Szweykowska-Kulińska
Zofia
Z
D002352:Carrier Proteins / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D008745:Methylation; D035683:MicroRNAs / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000378:metabolism; D034743:RNA-Induced Silencing Complex / Q000378:metabolism; D020539:Sequence Analysis, Protein
D002352:Carrier Proteins; D035683:MicroRNAs; D010940:Plant Proteins; D016601:RNA-Binding Proteins; D034743:RNA-Induced Silencing Complex