title: Pleural epithelioid hemangioendothelioma.
abstract: Epithelioid hemangioendothelioma (EHE) is a rare tumor of vascular origin. While it can be found in any tissue, it is most often found in lung and liver and usually has an intermediate behavior. EHEs originating from pleural tissue have been less frequently described than those from other sites. Furthermore, to date, all of the cited pleural EHEs were described as highly aggressive. In the present report, we describe a rare case of pleural EHE extending to lung and bone in a 31-year-old woman. The histological diagnosis was confirmed by both conventional examination and immunohistochemistry. Her disease stabilized during the 4th course of adriamycin (45 mg/m(2), day 1-3), dacarbazine (300 mg/m(2), day 1-3) and ifosfamide (2,500 mg/m(2), day 1-3) with mesna, and she survived for 10 months after the diagnosis.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Young Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Moon Jae
authors.initials: MJ
authors.lastname: Chung
authors.forename: Ki Cheon
authors.initials: KC
authors.lastname: Jeong
authors.forename: Chang Hoon
authors.initials: CH
authors.lastname: Hahn
authors.forename: Ki Pyo
authors.initials: KP
authors.lastname: Hong
authors.forename: Yee-Jeong
authors.initials: YJ
authors.lastname: Kim
authors.forename: Yong Tai
authors.initials: YT
authors.lastname: Kim
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000378:metabolism; D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D008175:Lung Neoplasms / Q000175:diagnosis; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D014746:Vimentin / Q000378:metabolism
chemical_list: D014746:Vimentin; D007633:Keratins; D005169:Factor VIII