title: Palladium-catalyzed cross-coupling reactions of benzyl indium reagents with aryl iodides.
abstract: Herein described is an operationally simple procedure for generating benzyl indium species from readily available benzyl bromides and indium metal followed by in situ palladium-catalyzed coupling with aryl halides. The procedure provides diarylmethanes in modest to excellent yield and tolerates a variety of functional groups in both coupling partners.
authors.affiliation: Groton Laboratories, Pfizer Inc., Eastern Point Road, 8220/2255, Groton, Connecticut 06340, USA.
authors.forename: Louis S
authors.initials: LS
authors.lastname: Chupak
authors.forename: Joanna P
authors.initials: JP
authors.lastname: Wolkowski
authors.forename: Yves A
authors.initials: YA
authors.lastname: Chantigny
mesh_terms: D001559:Benzhydryl Compounds / Q000138:chemical synthesis*; D001593:Benzyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry; D007204:Indium / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
chemical_list: D001559:Benzhydryl Compounds; D001593:Benzyl Compounds; D006842:Hydrocarbons, Brominated; D007462:Iodobenzenes; D009942:Organometallic Compounds; D007204:Indium; D010165:Palladium; C010129:diphenylmethane