title: [A case of submucosal invasive cancer of the sigmoid colon, recurring as multiple liver metastases one year after the surgery].
abstract: A 55-year-old woman underwent colonoscopy due to a positive fecal occult blood test during a mass screening examination, and a 0-Ip type early cancer in the sigmoid colon was found. Endoscopic mucosal resection was performed for this lesion. Histological examination of the endoscopic resected specimen showed a well-differentiated adenocarcinoma invading submucosal layer (depth of invasion, 6,000 microm), positive lymph vessel invasion, and cut end negative. The patient was referred to our hospital, and an additional sigmoidectomy with lymphadenectomy was conducted. Histological examination revealed no residual cancer and no lymph node metastasis. One year after the surgery, an abdominal CT scan showed liver metastases in the segment 4 and 7. The patient underwent a medial segmentectomy and partial resection of the segment 7 of the liver. After the surgery, 8 courses of oral UFT/LV therapy as adjuvant chemotherapy were administered. The patient remains free of recurrence 2 years and 7 months after the first surgery.
authors.affiliation: Dept. of Surgery, Metropolitan Komagome Hospital.
authors.forename: Tatsuto
authors.initials: T
authors.lastname: Nishigori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Nakano
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Manabu
authors.initials: M
authors.lastname: Ohashi
authors.forename: Souya
authors.initials: S
authors.lastname: Nunobe
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iwanaga
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nemoto
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Funada
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nakaya
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ookura
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D003113:Colonoscopy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D012008:Recurrence; D012811:Sigmoid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents