title: Stable preformed chiral palladium catalysts for the one-pot asymmetric reductive amination of ketones.
abstract: The application of air stable preformed [(R)-BINAP]PdBr2, [(S)-BINAP]PdBr2, [(R)-Tol-BINAP]PdBr2, and [(S,S)-CHIRAPHOS]PdBr2 complexes in the one-pot asymmetric reductive amination of various carbonyl compounds, leading to chiral amines in very good yields with high enantioselectivities (<99% ee), is reported.
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México, 04510, DF, México. laurarpz@correo.unam.mx
authors.forename: Laura
authors.initials: L
authors.lastname: Rubio-Pérez
authors.forename: F Javier
authors.initials: FJ
authors.lastname: Pérez-Flores
authors.forename: Pankaj
authors.initials: P
authors.lastname: Sharma
authors.forename: Luis
authors.initials: L
authors.lastname: Velasco
authors.forename: Armando
authors.initials: A
authors.lastname: Cabrera
mesh_terms: D000388:Air; D000586:Amination; D000814:Aniline Compounds / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D006859:Hydrogen / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000814:Aniline Compounds; D007659:Ketones; D010165:Palladium; D006859:Hydrogen; C023650:aniline