title: [Carcinoma of the gallbladder--current surgical treatment options].
abstract: BACKGROUND
  The effect of radical resection in gallbladder cancer is still area of debate.
  
  
  OBJECTIVE
  To determine the criteria of surgery in primary and incidental gallbladder cancer. method: Eighty-four patients with gallbladder cancer were evaluated between 1999 and 2008. Sixty patients (72.4%) were symptomatic. Explorative laparotomy was performed in 40 (66.7%), palliative procedure in 5 (8.3%) patients in stage pT3-4, N1, M0-1. Cholecystectomy only or completed with wedge resection of the gallbladder bed and lymfadenectomy as radical procedure was performed only in 7 (1.7%) patients in pT1-2, N0-1, M0. Twenty four (28.6%) patients had incidental gall bladder carcinoma. Radical cholecystectomy was performed in 4 (16.7%) - pT1a, N0, M0, palliative cholecystectomy in 3 patients (12.5%) - pT3, N1, M0. Radical reoperation was performed in 15 (62.5%) patients in stage pT1b-2, N0-1, M0.
  
  
  RESULTS
  Patients survival after explorative laparotomy and palliative procedures was no longer than 7 months. Four from seven patients died after radical operation 12-18 months after operation. Six from 15 radically re-operated patients are alive in interval 4 months and 8 years. Nine patients died in interval 9 months and 4 years after re-operation.
  
  
  CONCLUSIONS
  Radical surgical procedure is the treatment of choice for patients with gall bladder carcinoma especially in stage pT1-2, N0, M0.
authors.affiliation: Chirurgická klinika LF UK a FN v Plzni. treska@fnplzen.cz
authors.forename: V
authors.initials: V
authors.lastname: Treska
authors.forename: T
authors.initials: T
authors.lastname: Skalický
authors.forename: A
authors.initials: A
authors.lastname: Sutnar
authors.forename: V
authors.initials: V
authors.lastname: Liska
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002763:Cholecystectomy; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation