[Clinical analysis of post pancreatoduodenectomy hemorrhage].
OBJECTIVE
To explore the factors of post pancreatoduodenectomy hemorrhage.


METHODS
The clinical data of 263 cases between January 1998 and April 2008 underwent pancreatoduodenectomy were analyzed prospectively.


RESULTS
The overall mortality rate was 4.94% (13/263). Postoperative bleeding occurred in 23 patients (8.75%), with 8 episodes ending fatally (34.8%). The tumor size, Child classification, caput total resection and pancreatic leakage were identified as significant risk factors for post pancreatoduodenectomy hemorrhage by means of univariate analysis. The multivariate Logistic regression analysis revealed that all of the five factors turned out to be the independent risk factors.


CONCLUSIONS
The prevention of these bleeding complications depends in the first place on meticulous hemostatic technique. The pancreatic leakage is also one of the most important factors due to postoperative bleeding. The prophylactic use of somatostatin is not necessary.
GAO
Song
S
Department of General Surgery, First Hospital, Peking University, Beijing 100034, China.
YANG
Yin-mo
YM
CAI
Meng-shan
MS
WU
Wen-han
WH
LIU
Zhan-bing
ZB
Zhuang
Yan
Y
ZHAO
Jian-xun
JX
WAN
Yuan-lian
YL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016577:Pancreaticoduodenectomy; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors