[Profile of selected cytokines in various forms of uveitis].
OBJECTIVE
The estimation of the level of selected inflammatory mediators in serum of patients with various types of uveitis.


METHODS
The level of IL-1, IL-6 and TNF was assessed by means of microbiological tests and ELISA test in the group of 60 patients with uveitis, divided as regards to the character of uveitis and the type of the treatment and in control group.


RESULTS
The levels of IL-1, IL-6 and TNF were higher in serum of patients with uveitis then in the control group. Patients with known etiology of uveitis had higher level of IL-6 and TNE Patients with autoimmunological etiology of uveitis had higher level of IL-1 and IL-6 than volunteers in control group.


CONCLUSIONS
Higher levels of cytokines in serum of patients with uveitis than in control group indicate the activation of immunological response in various types of uveitis.
Rusiecka-Ziółkowska
Jolanta
J
Z Katedry i Zakładu Mikrobiologii Akademii Medycznej we Wrocławiu. joda@mbio.am.wroc.pl
Turno-Krecicka
Anna
A
Białek-Szymańska
Anna
A
Salomon
Ewa
E
D000328:Adult; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D007375:Interleukin-1 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*; D014605:Uveitis / Q000097:blood* / Q000175:diagnosis
D015415:Biomarkers; D018836:Inflammation Mediators; D007375:Interleukin-1; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha