Gastrointestinal tract pseudo-obstruction or obstruction due to Mycobacterium tuberculosis breakthrough.
The development of tuberculosis-related bowel obstruction or pseudo-obstruction during anti-tuberculosis therapy is rarely reported in immunocompetent patients. A 44-year-old male, who had neither HIV infection nor diabetes, was hospitalized because of pulmonary tuberculosis in November 2006. Three months after starting anti-tuberculosis therapy, he was admitted for suspected mechanical bowel obstruction. An emergency exploratory laparotomy showed distended bowel loops, and multiple skip lesions from the terminal ileum to the ascending colon. PCR analyses showed Mycobacterium tuberculosis. The therapy regimen was unchanged after the operation; the patient gradually improved over the course of a month and was discharged without further symptoms thereafter.
Lee
Chien-Wei
CW
Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Chang
Wen-Hsiung
WH
Shih
Shou-Chuan
SC
Wang
Tsang-En
TE
Chang
Chen-Wang
CW
Bair
Ming-Jong
MJ
Chiang
Ruey-An
RA
Chen
Yu-Jan
YJ
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003106:Colon / Q000382:microbiology; D006801:Humans; D007082:Ileum / Q000382:microbiology; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D007418:Intestinal Pseudo-Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D013183:Sputum / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy
D000995:Antitubercular Agents