title: Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles.
abstract: OBJECTIVE
  To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  An IVF laboratory in a university hospital in Taiwan.
  
  
  METHODS
  Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group.
  
  
  METHODS
  None.
  
  
  METHODS
  Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer.
  
  
  RESULTS
  The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group.
  
  
  CONCLUSIONS
  A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Niaosung Hsiang, Kaohsiung, Taiwan.
authors.forename: Yu-Che
authors.initials: YC
authors.lastname: Ou
authors.forename: Kuo-Chung
authors.initials: KC
authors.lastname: Lan
authors.forename: Fu-Jen
authors.initials: FJ
authors.lastname: Huang
authors.forename: Fu-Tsai
authors.initials: FT
authors.lastname: Kung
authors.forename: Ting-Hsun
authors.initials: TH
authors.lastname: Lan
authors.forename: Shiuh Young
authors.initials: SY
authors.lastname: Chang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007246:Infertility / Q000628:therapy*; D050498:Live Birth; D008297:Male; D008875:Middle Aged; D054315:Oocyte Retrieval; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D013624:Taiwan; D016896:Treatment Outcome