In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing.
The spectrum of activity of ceftaroline was evaluated against 1,247 bacterial isolates representing 44 different species or phenotypic groups. For the majority of species, the activity of ceftaroline was comparable or superior to that of ceftriaxone. MIC and/or disk diffusion quality control ranges of ceftaroline were determined for five standard ATCC reference strains.
Brown
Steven D
SD
The Clinical Microbiology Institute, 9725 SW Commerce Circle, Wilsonville, Oregon 97070, USA. SBrown@clinmicroinst.com
Traczewski
Maria M
MM
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002443:Ceftriaxone / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D003470:Culture Media; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011786:Quality Control; D000097583:Ceftaroline
D000900:Anti-Bacterial Agents; D002443:Ceftriaxone; D002511:Cephalosporins; D003470:Culture Media; D000097583:Ceftaroline