title: [Plant micro RNA biogenesis].
abstract: Micro RNAs are 21-24 nt long RNA molecules involved in the regulation of gene expression on mRNA level. Mature miRNA molecules associated with the RNA-induced silencing complex (RISC) guide specifically mRNA cleavage or inhibit the translation. In plants selective mRNA degradation in miRNA-dependent pathway is a widespread mechanism that occurs more frequently than translation inhibition. miRNA precursors, known as pri-miRNA, are processed in several steps to produce mature miRNA molecules. There are several plant proteins involved in miRNA processing: DCL1, HYL1, SE, HEN1 and HASTY. The role of these proteins is discussed.
authors.affiliation: Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 5 Miedzychodzka St., 60-371 Poznan, Poland.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Sobkowiak
authors.forename: Bogna
authors.initials: B
authors.lastname: Szarzyńska
authors.forename: Zofia
authors.initials: Z
authors.lastname: Szweykowska-Kulińska
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D008745:Methylation; D035683:MicroRNAs / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000378:metabolism; D034743:RNA-Induced Silencing Complex / Q000378:metabolism; D020539:Sequence Analysis, Protein
chemical_list: D002352:Carrier Proteins; D035683:MicroRNAs; D010940:Plant Proteins; D016601:RNA-Binding Proteins; D034743:RNA-Induced Silencing Complex