[Comparison of DK crush with classical crush technique with drug-eluting stents for the treatment of coronary bifurcation lesions from DKCRUSH-1 study].
OBJECTIVE
To determine independent factors correlated with clinical effects of DK crush and classical crush technique with drug-eluting stents on bifurcation lesions.


METHODS
311 patients with bifurcation lesions were randomized to classical (C, n = 156) or double kissing (DK) crush (n = 155) stent implantation group. The primary endpoints included major adverse cardiac events (MACE).


RESULTS
Final kissing balloon inflation (FKBI) success rate was 76% in C and 100% in DK groups (P < 0.001). DK crush procedure was characterized by lower unsatisfactory FKBI rate (27.6% vs.6.3%, P < 0.01). Clinical follow-up was available in 100% and angiographic follow-up in 82% patients. The overall restenosis rate was 32.3% in C and 20.3% in DK groups (P = 0.01), respectively. Cumulative 8-month MACE was 35.9% in without-FKBI and 19.7% in with-FKBI sub-groups, and 11.4% in DK group (P = 0.02). The incidence of stent thrombosis was 3.2% in C group (5.1% without vs. 1.7% with FKBI) and 1.3% in DK group (P > 0.05). The predictive factors of MACE included minimal side branch stent lumen diameter and lack of DK crush technique.


CONCLUSIONS
DK crush technique is an alternative of double stenting techniques in terms of improvement of restenosis and clinical outcomes.
Chen
Shao-liang
SL
Department of Cardiology, Nanjing First Hospital, Nanjing Medical College, Nanjing 210006, China. chmengx@126.com
Zhang
Jun-jie
JJ
Ye
Fei
F
Chen
Yun-dai
YD
Lü
Shu-zheng
SZ
Tan
Huaycheem
H
Patel
Tejas
T
Kenji
Kawajiri
K
Tamari
Israel
I
Shan
Shou-jie
SJ
Zhu
Zhong-sheng
ZS
Lin
Song
S
Tian
Nai-liang
NL
Li
Xiao-bo
XB
Liu
Zhi-zhong
ZZ
Lee
Michael
M
Wei
Meng
M
Xu
Ya-wei
YW
Yuan
Zheng-bai
ZB
Qian
Jun
J
Sun
Xue-wen
XW
Yang
Song
S
Chen
Jin-guo
JG
He
Ben
B
Sumit
Suji
S
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D003324:Coronary Artery Disease / Q000628:therapy*; D023921:Coronary Stenosis / Q000628:therapy; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents