title: Synthesis of water-soluble phthalocyanines bearing four or eight D-galactose units.
abstract: The synthesis and structural characterization of two glycophthalocyanines with four or eight unprotected D-galactose units is reported. The sugar units are linked to the macrocycle via the hydroxyl group located at C-6. The water solubility promoted by the carbohydrate moieties provides a potential application of these phthalocyanine derivatives as photosensitizers in photodynamic therapy.
authors.affiliation: Departamento de Química, QOPNA, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Ana R M
authors.initials: AR
authors.lastname: Soares
authors.forename: João P C
authors.initials: JP
authors.lastname: Tomé
authors.forename: Maria G P M S
authors.initials: MG
authors.lastname: Neves
authors.forename: Augusto C
authors.initials: AC
authors.lastname: Tomé
authors.forename: José A S
authors.initials: JA
authors.lastname: Cavaleiro
authors.forename: Tomás
authors.initials: T
authors.lastname: Torres
mesh_terms: D005690:Galactose / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D054833:Isoindoles; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D007211:Indoles; D054833:Isoindoles; D014867:Water; C013647:phthalocyanine; D005690:Galactose