title: Acute aortic dissection: perspectives from the International Registry of Acute Aortic Dissection (IRAD).
abstract: Acute aortic dissection is a rare but deadly disease first described over 200 years ago by the physician to the late King George II on necropsy. Over the ensuing 2 centuries, the understanding of the pathophysiology, presentation, diagnosis, treatment and follow-up has matured. In an effort to understand the contemporary treatment of this disease, the International Registry of Acute Aortic Dissection (IRAD) has enrolled over 2000 patients over the past 12 years. In this article we summarize the key lessons learned from this multi-national registry of patients presenting with acute aortic dissection.
authors.affiliation: Health Services Research and Development Center, Denver Veterans Affairs Medical Center, 1055 Clermont Street, Denver, CO 80220, USA. thomas.tsai@ucdenver.edu
authors.forename: T T
authors.initials: TT
authors.lastname: Tsai
authors.forename: S
authors.initials: S
authors.lastname: Trimarchi
authors.forename: C A
authors.initials: CA
authors.lastname: Nienaber
mesh_terms: D000208:Acute Disease; D000368:Aged; D000784:Aortic Dissection / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D018450:Disease Progression; D005260:Female; D006406:Hematoma / Q000150:complications; D017052:Hospital Mortality; D006801:Humans; D007391:International Cooperation; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012042:Registries; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality