Understanding the molecular epidemiology of foot-and-mouth-disease virus.
The use of molecular epidemiology is an important tool in understanding and consequently controlling FMDV. In this review I will present basic information about the disease, needed to perform molecular epidemiology. I will give a short introduction to the history and impact of foot-and-mouth disease, clinical picture, infection route, subclinical and persistent infections, general aspects of the transmission of FMDV, serotype-specific epidemiological characteristics, field epidemiology of FMDV, evolution and molecular epidemiology of FMDV. This is followed by two chapters describing the molecular epidemiology of foot-and-mouth disease in global surveillance and molecular epidemiology of foot-and-mouth disease in outbreak investigation.
Klein
Joern
J
Norwegian University of Science and Technology, Faculty of Medicine, Department of Cancer Research and Molecular Medicine, N-7489 Trondheim, Norway. jorn.klein@ntnu.no
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000635:transmission / Q000821:virology*; D004197:Disease Reservoirs / Q000662:veterinary; D018562:Disease Transmission, Infectious / Q000662:veterinary; D005536:Foot-and-Mouth Disease / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D029544:Foot-and-Mouth Disease Virus / Q000235:genetics / Q000276:immunology* / Q000502:physiology; D017720:Molecular Epidemiology
D000914:Antibodies, Viral