Reconstitution inflammatory syndrome related to histoplasmosis, with a hemophagocytic syndrome in HIV infection.
Immune reconstitution after initiation of antiretroviral therapy may unmask a latent infection. We report a case of disseminated Histoplasma capsulatum capsulatum infection associated with a hemophagocytic syndrome in an HIV-infected patient, three weeks after initiation of antiretroviral therapy. The immune reconstitution inflammatory syndrome might be a risk factor for hemophagocytosis.
De Lavaissière
Marc
M
Service de Médecine Interne, Hôpital Bicêtre, AP-HP, Le Kremlin Bicêtre, France.
Manceron
Véronique
V
Bourée
Patrice
P
Garçon
Loïc
L
Bisaro
Francine
F
Delfraissy
Jean-François
JF
Lambotte
Olivier
O
Goujard
Cécile
C
D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic; D008297:Male
D019380:Anti-HIV Agents