title: Effect of gelatinization on gastric emptying and absorption.
abstract: OBJECTIVE
  For gastrointestinal functional analysis such as gastric emptying tests, either a liquid or solid meal is used as a test meal. Only a few studies have compared meal characteristics, such as liquid and solid. No previous study has compared test meals that had the same composition but different properties. The aim of this study was to compare the gastric emptying and absorption obtained by 13C-breath test after ingestion of liquid or gelatinized liquid nutrients.
  
  
  METHODS
  Ten healthy volunteers were studied four times, with 2-week intervals. For the test meal, 200 mL of liquid meals (200 kcal) and gelatinized liquid meals were used. Gelatinized liquid nutrients were prepared by mixing 6 g, 12 g and 18 g of Natural psyllium husk with 200 mL of liquid meals. Breath samples were collected for four hours. Gastric emptying were expressed as the time of peak excretion, absorption were expressed as the area under the 13CO2 curve up to the time of peak excretion.
  
  
  RESULTS
  Gastric emptying times were 54.5, 54.5, 81.7 and 93.3 min. Absorption was 20.8, 20.9, 27.8 and 29.8% dose.
  
  
  CONCLUSIONS
  Gelatinization influences gastric emptying, but does not influence absorption. Gelatinized liquid meals may be useful for a substitute for solid meals on gastrointestinal functional analysis.
authors.affiliation: Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan. naruk0501@yahoo.co.jp
authors.forename: Naruo
authors.initials: N
authors.lastname: Kawasaki
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Urashima
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nakayoshi
authors.forename: Kazuto
authors.initials: K
authors.lastname: Tsuboi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Tanishima
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Hanyu
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kashiwagi
mesh_terms: D000328:Adult; D019540:Area Under Curve; D001944:Breath Tests / Q000379:methods*; D005260:Female; D005746:Gastric Emptying; D005782:Gels / Q000737:chemistry*; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D011620:Psyllium
chemical_list: D005782:Gels; D011620:Psyllium