Comparison of OCT and HRT findings among normal, normal tension glaucoma, and high tension glaucoma.
OBJECTIVE
To evaluate the relationship between optic disc and retinal nerve fiber layer (RNFL) measurements obtained with the optical coherence tomography (OCT) and the Heidelberg retina topography (HRT) in normal, normal tension glaucoma (NTG), and high tension glaucoma (HTG).


METHODS
Normal, NTG and HTG subjects who met inclusion and exclusion criteria were evaluated retrospectively. One hundred seventy eyes of 170 patients (30 normal, 40 NTG, and 100 HTG) were enrolled. Complete ophthalmologic examination, HRT, OCT, and automated perimetry were evaluated.


RESULTS
Disc area, cup area and cup/disc area ratio measured with HRT were significantly different between NTG and HTG (all p < 0.05). Mean RNFL thickness measured by OCT with ascanning diameter of 3.4 mm was larger in NTG than HTG (84.97+/-24.20 micrometer vs. 73.53+/-27.17 micrometer, p = 0.037). Four quadrant RNFL thickness measurements were not significantly different between NTG and HTG (all p > 0.05). Mean deviation and corrected pattern standard deviation measured by automated perimetry was significantly correlated with mean and inferior RNFL thickness in both NTG and HTG (Pearson's r, p < 0.05). Mean RNFL thickness/disc area ratio was significantly larger in HTG than NTG (35.21+/-18.92 vs. 31.30+/-10.91, p = 0.004).


CONCLUSIONS
These findings suggest that optic disc and RNFL damage pattern in NTG may be different from those of HTG.
Shin
In Ha
IH
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Kang
Sung Yong
SY
Hong
Samin
S
Kim
Seung Kab
SK
Seong
Gong Je
GJ
Tak
Ma Kyung
MK
Kim
Chan Yun
CY
D000328:Adult; D000368:Aged; D001369:Axons / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D058609:Visual Field Tests; D014794:Visual Fields