Specificity of reflex adaptation for task-relevant variability.
The motor system responds to perturbations with reflexes, such as the vestibulo-ocular reflex or stretch reflex, whose gains adapt in response to novel and fixed changes in the environment, such as magnifying spectacles or standing on a tilting platform. Here we demonstrate a reflex response to shifts in the hand's visual location during reaching, which occurs before the onset of voluntary reaction time, and investigate how its magnitude depends on statistical properties of the environment. We examine the change in reflex response to two different distributions of visuomotor discrepancies, both of which have zero mean and equal variance across trials. Critically one distribution is task relevant and the other task irrelevant. The task-relevant discrepancies are maintained to the end of the movement, whereas the task-irrelevant discrepancies are transient such that no discrepancy exists at the end of the movement. The reflex magnitude was assessed using identical probe trials under both distributions. We find opposite directions of adaptation of the reflex response under these two distributions, with increased reflex magnitudes for task-relevant variability and decreased reflex magnitudes for task-irrelevant variability. This demonstrates modulation of reflex magnitudes in the absence of a fixed change in the environment, and shows that reflexes are sensitive to the statistics of tasks with modulation depending on whether the variability is task relevant or task irrelevant.
Franklin
David W
DW
Computational and Biological Learning Laboratory, Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, UK. dwf25@cam.ac.uk
Wolpert
Daniel M
DM
D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D000704:Analysis of Variance; D001696:Biomechanical Phenomena; D003220:Conflict, Psychological; D004576:Electromyography / Q000379:methods; D005246:Feedback / Q000502:physiology; D005260:Female; D007839:Functional Laterality; D006225:Hand / Q000502:physiology; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D011187:Posture; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012018:Reflex / Q000502:physiology*; D013998:Time Perception / Q000502:physiology; D014785:Vision, Ocular / Q000502:physiology