title: Persistent vancomycin and high-level gentamicin-resistant Enterococcus faecium bacteremia and intra-aortic thrombus in an extremely low birth-weight infant.
abstract: Vancomycin-resistant Enterococcus (VRE) sepsis is emerging as a significant problem in the intensive care setting. The treatment at any age is challenging, but there is a dearth of information on this infection and its treatment in the very premature infant. We describe successful treatment of persistent bacteremia caused by Enterococcus faecium with vancomycin and high-level gentamicin resistance in a 10-day-old former 23-week premature male infant.
authors.affiliation: Department of Neonatology, The National Maternity Hospital, Dublin, Ireland. ninahapnes@hotmail.com
authors.forename: N
authors.initials: N
authors.lastname: Hapnes
authors.forename: A
authors.initials: A
authors.lastname: Twomey
authors.forename: S
authors.initials: S
authors.lastname: Knowles
mesh_terms: D001018:Aortic Diseases / Q000188:drug therapy / Q000382:microbiology*; D016470:Bacteremia / Q000150:complications / Q000188:drug therapy; D004200:Diseases in Twins; D024901:Drug Resistance, Multiple, Bacterial; D016984:Enterococcus faecium / Q000302:isolation & purification*; D017809:Fatal Outcome; D005839:Gentamicins / Q000627:therapeutic use*; D005865:Gestational Age; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D013927:Thrombosis / Q000188:drug therapy / Q000382:microbiology*; D014640:Vancomycin / Q000627:therapeutic use*
chemical_list: D005839:Gentamicins; D014640:Vancomycin