title: Reconstitution inflammatory syndrome related to histoplasmosis, with a hemophagocytic syndrome in HIV infection.
abstract: Immune reconstitution after initiation of antiretroviral therapy may unmask a latent infection. We report a case of disseminated Histoplasma capsulatum capsulatum infection associated with a hemophagocytic syndrome in an HIV-infected patient, three weeks after initiation of antiretroviral therapy. The immune reconstitution inflammatory syndrome might be a risk factor for hemophagocytosis.
authors.affiliation: Service de Médecine Interne, Hôpital Bicêtre, AP-HP, Le Kremlin Bicêtre, France.
authors.forename: Marc
authors.initials: M
authors.lastname: De Lavaissière
authors.forename: Véronique
authors.initials: V
authors.lastname: Manceron
authors.forename: Patrice
authors.initials: P
authors.lastname: Bourée
authors.forename: Loïc
authors.initials: L
authors.lastname: Garçon
authors.forename: Francine
authors.initials: F
authors.lastname: Bisaro
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Delfraissy
authors.forename: Olivier
authors.initials: O
authors.lastname: Lambotte
authors.forename: Cécile
authors.initials: C
authors.lastname: Goujard
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic; D008297:Male
chemical_list: D019380:Anti-HIV Agents