Diffuse gastrointestinal involvement of mantle cell lymphoma.
The gastrointestinal tract is the predominant site of appearance of extranodal non-Hodgkin lymphomas. The most frequent endoscopic finding of mantle cell lymphoma is multiple lymphomatous polyposis, which is a very rare entity. Multiple lymphomatous polyposis is characterized by multiple polypoid lesions involving long segments of the gastrointestinal tract and it accounts for 2% of primary gastrointestinal tract lymphomas. A 68-year-old patient was admitted to our clinic with intermittent diarrhea, weight loss, hematochezia and fatigue. Multiple lymphomatous polyposis was detected on the endoscopic evaluations. Gastrointestinal mantle cell lymphoma was confirmed with histopathological and immunohistochemical studies on biopsy specimens from colon, small intestine and stomach. The patient was successfully treated by combination chemotherapy.
Meral
Murat
M
Department of Gastroenterology, Dokuz Eylul University Medical Faculty, Izmir, Turkey. murat.meral@deu.edu.tr
Demirpençe
Mustafa
M
Gönen
Can
C
Akarsu
Mesut
M
Kayahan
Hasan
H
Demirkan
Fatih
F
Kargi
Aydanur
A
Akpinar
Hale
H
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001464:Barium; D001706:Biopsy; D003106:Colon / Q000473:pathology; D003287:Contrast Media; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D016145:Endoscopy, Digestive System; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D044483:Intestinal Polyposis / Q000175:diagnosis* / Q000188:drug therapy; D007421:Intestine, Small / Q000473:pathology; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
D003287:Contrast Media; D001464:Barium; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone