Role of lipid emulsion administration in acute lung injury during liver transplant rejection: a case report.
We report the case of a 58-year-old woman who developed rejection and acute lung injury 10 days after an orthotopic liver transplantation while receiving total parenteral nutrition. Examination of bronchoalveolar lavage fluid revealed large lipid droplets in the alveolar macrophages. Intensification of the immunosuppressive therapy attenuated the liver allograft rejection followed by resolution of lung injury.
Kostopanagiotou
G
G
Second Department of Anesthesiology, University of Athens School of Medicine, Attikon Hospital, Athens, Greece.
Kalimeris
K
K
Arkadopoulos
N
N
Karakitsos
P
P
Smyrniotis
V
V
Pandazi
A
A
D055371:Acute Lung Injury / Q000188:drug therapy*; D001379:Azathioprine / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004655:Emulsions; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008055:Lipids / Q000032:analysis*; D008103:Liver Cirrhosis / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D016676:Macrophages, Alveolar / Q000473:pathology; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D010289:Parenteral Nutrition, Total; D016896:Treatment Outcome
D004655:Emulsions; D007166:Immunosuppressive Agents; D008055:Lipids; D016572:Cyclosporine; D001379:Azathioprine; D008775:Methylprednisolone