Total synthesis of pseudodehydrothyrsiferol.
An enantioselective total synthesis of pseudodehydrothyrsiferol has been accomplished. The synthetic sequence highlights formation of the highly strained tetrahydropyran C-ring by a Mitsunobu-type S(N)2 reaction with an oxygen nucleophile.
Hioki
Hideaki
H
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Motosue
Masatoshi
M
Mizutani
Yasuhiko
Y
Noda
Akira
A
Shimoda
Tomoaki
T
Kubo
Miwa
M
Harada
Kenichi
K
Fukuyama
Yoshiyasu
Y
Kodama
Mitsuaki
M
D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D044722:Laurencia / Q000737:chemistry; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D005663:Furans; D011714:Pyrans; C538698:pseudodehydrothyrsiferol; C410452:thyrsiferol