title: [Labour epidural analgesia for a woman with a factor XI deficiency: an illconsidered risk?].
abstract: Inherited bleeding disorders contraindicate epidural analgesia because of the risk of epidural haematoma. However, there is no consensus about a minimal rate of factor XI required for its performance. We report here a case of epidural analgesia in a pregnant woman with a moderate and symptomatic factor XI deficiency, despite this theoretical contraindication. Indeed, the factor XI deficiency results in a haemorrhagic risk which is variable and not easily foreseeable. Nevertheless, no neurological after-effect or excessive bleeding occurred although no specific prophylaxis had been performed.
authors.affiliation: Service d'anesthésie-réanimation, hôpital de mère et de l'enfant, 8, avenue Dominique-Larrey, 87042 Limoges cedex, France. georgespep@yahoo.fr
authors.forename: F
authors.initials: F
authors.lastname: Pepino
authors.forename: P
authors.initials: P
authors.lastname: Granchamp
authors.forename: I
authors.initials: I
authors.lastname: Odin
authors.forename: E
authors.initials: E
authors.lastname: Decroisette
authors.forename: N
authors.initials: N
authors.lastname: Nathan
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural / Q000009:adverse effects*; D016362:Analgesia, Obstetrical / Q000009:adverse effects*; D005172:Factor XI / Q000502:physiology* / Q000627:therapeutic use; D005173:Factor XI Deficiency / Q000150:complications*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006470:Hemorrhage / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D010976:Platelet Count; D011247:Pregnancy; D018570:Risk Assessment
chemical_list: D006454:Hemoglobins; D005172:Factor XI