title: Outcomes for intermediate risk prostate cancer: are there advantages for surgery, external radiation, or brachytherapy?
abstract: The treatment of localized prostate cancer remains controversial because of the lack of conclusive well-controlled or randomized studies comparing outcome of various forms of radiotherapy (RT) to radical prostatectomy (RP). We review recent results from an institutional database and prospective quality of life study comparing cancer-related and quality of live (QOL) outcomes among different treatment modalities for intermediate risk prostate cancer. The results suggest similar short-term survival but domain-specific effects on QOL after treatment with radical prostatectomy, brachytherapy, or external beam radiotherapy.
authors.affiliation: Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA. KLEINE@ccf.org
authors.forename: Eric A
authors.initials: EA
authors.lastname: Klein
authors.forename: Jay
authors.initials: J
authors.lastname: Ciezki
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Kupelian
authors.forename: Arul
authors.initials: A
authors.lastname: Mahadevan
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008495:Medical Oncology / Q000379:methods*; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D011788:Quality of Life; D011878:Radiotherapy / Q000379:methods*; D012306:Risk; D013997:Time Factors; D016896:Treatment Outcome