Detection of viruses in human adenoid tissues by use of multiplex PCR.
By PCR, we detected a high frequency of viruses in adenoids obtained from children without acute respiratory symptoms. Our results suggest that persistent/latent viral infection in the respiratory tract confounds interpretation of the association of pathogen detection by PCR with acute respiratory infection in these sources.
Sato
Masatoki
M
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Li
Haijing
H
Ikizler
Mine R
MR
Werkhaven
Jay A
JA
Williams
John V
JV
Chappell
James D
JD
Tang
Yi-Wei
YW
Wright
Peter F
PF
D000234:Adenoids / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods*; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*