title: Effects of compounds isolated from the fruits of Rumex japonicus on the protein glycation.
abstract: An anthraquinone, emodin (1), and five flavonoids, kaempferol-3-O-beta-D-glucoside (2), quercetin (3), quercitrin (4), isoquercitrin (5), and (+)-catechin (6), were isolated from an AcOEt-soluble extract of the fruits of Rumex japonicus. Their structures were determined by spectroscopic data interpretation. All the isolates were evaluated for their potential to inhibit AGEs (advanced glycation end products) formation and AGEs cross-linking, and to break already formed AGEs cross-links.
authors.affiliation: Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine, Daejeon, Korea.
authors.forename: Dae Sik
authors.initials: DS
authors.lastname: Jang
authors.forename: Jong Min
authors.initials: JM
authors.lastname: Kim
authors.forename: Junghyun
authors.initials: J
authors.lastname: Kim
authors.forename: Jeong Lim
authors.initials: JL
authors.lastname: Yoo
authors.forename: Young Sook
authors.initials: YS
authors.lastname: Kim
authors.forename: Jin Sook
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000085:Acetates / Q000737:chemistry; D005638:Fruit / Q000737:chemistry*; D017127:Glycation End Products, Advanced / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D019664:Polygonaceae / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry
chemical_list: D000085:Acetates; D017127:Glycation End Products, Advanced; D011506:Proteins; D012710:Serum Albumin, Bovine; C007650:ethyl acetate