title: Diffuse gastrointestinal involvement of mantle cell lymphoma.
abstract: The gastrointestinal tract is the predominant site of appearance of extranodal non-Hodgkin lymphomas. The most frequent endoscopic finding of mantle cell lymphoma is multiple lymphomatous polyposis, which is a very rare entity. Multiple lymphomatous polyposis is characterized by multiple polypoid lesions involving long segments of the gastrointestinal tract and it accounts for 2% of primary gastrointestinal tract lymphomas. A 68-year-old patient was admitted to our clinic with intermittent diarrhea, weight loss, hematochezia and fatigue. Multiple lymphomatous polyposis was detected on the endoscopic evaluations. Gastrointestinal mantle cell lymphoma was confirmed with histopathological and immunohistochemical studies on biopsy specimens from colon, small intestine and stomach. The patient was successfully treated by combination chemotherapy.
authors.affiliation: Department of Gastroenterology, Dokuz Eylul University Medical Faculty, Izmir, Turkey. murat.meral@deu.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Meral
authors.forename: Mustafa
authors.initials: M
authors.lastname: Demirpençe
authors.forename: Can
authors.initials: C
authors.lastname: Gönen
authors.forename: Mesut
authors.initials: M
authors.lastname: Akarsu
authors.forename: Hasan
authors.initials: H
authors.lastname: Kayahan
authors.forename: Fatih
authors.initials: F
authors.lastname: Demirkan
authors.forename: Aydanur
authors.initials: A
authors.lastname: Kargi
authors.forename: Hale
authors.initials: H
authors.lastname: Akpinar
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001464:Barium; D001706:Biopsy; D003106:Colon / Q000473:pathology; D003287:Contrast Media; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D016145:Endoscopy, Digestive System; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D044483:Intestinal Polyposis / Q000175:diagnosis* / Q000188:drug therapy; D007421:Intestine, Small / Q000473:pathology; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D001464:Barium; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone