title: [Lower respiratory tract infections with influenza and respiratory syncytial viruses in hospitalized elderly patients during the 2005-2006 winter season].
abstract: OBJECTIVE
  To assess the proportion of lower respiratory tract infections (LRTI) attributable to influenza virus and respiratory syncytial virus (RSV) during the 2005-2006 winter period, among hospitalized elderly in a geriatric unit of a French hospital near Paris and and describe the characteristics of these infections.
  
  
  METHODS
  In a geriatric unit with 115 beds, distributed as 14 in acute care (ACF), 21 in rehabilitation and intermediate-care (RICF) and 80 in long-term-care-facilities (LTCF), all patients over age 65 with LRTI were enrolled during a winter. Clinical and biological parameters were recorded including paired serology for influenza virus and RSV.
  
  
  RESULTS
  54 LRTI concerned 47 patients were recorded. 50 paired serums were analysed. Influenza virus or RSV were found in 17 cases (34%). The distribution of the cases was as follows: Influenza A in 5 cases, Influenza B in 3 cases, a co-infection with influenza A and B in 4 cases, RSV in 3 cases and co-infections with influenza and RSV in 2 cases (influenza A and RSV in one case and influenza A and B and RSV in the other case). 7 cases concerned patients in ACF, in 3 cases patients were in RICF and in 7 cases patients were in LTCF. 15 cases were nosocomial infections. 11 patients infected by influenza virus were vaccined. It was concluded as bronchitis in 8 cases, interstitial pneumonia in 6 cases and alveolar pneumonia in 3 cases. Antibiotics were prescribed in 11 cases. In one case the evolution was unfavourable with death. Patients with influenza or RSV infections had significantly more rales and rhonchi compared with patients non infected by these virus (p<0.05).
  
  
  CONCLUSIONS
  Influenza and RSV are an important cause of LRTI in elderly during the winter months, influenza infections can occurring among vaccinated elderly. It seems necessary to achieve further clinical studies about LRTI in elderly and to study the impact of rapid diagnostic tests to improve the management of these infections.
authors.affiliation: Service de Gériatrie, Hôpital Charles RICHET, Assistance-Publique-Hôpitaux de Paris, F-95400 Villiers Le Bel, France. nicole.haber@crc.aphp.fr
authors.forename: Nicole
authors.initials: N
authors.lastname: Haber
authors.forename: Siham
authors.initials: S
authors.lastname: Dekimeche
authors.forename: Cyrille
authors.initials: C
authors.lastname: Cantet
authors.forename: Dominique
authors.initials: D
authors.lastname: Marquand
authors.forename: Carol
authors.initials: C
authors.lastname: Szekely
authors.forename: Pierre
authors.initials: P
authors.lastname: Lebon
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001991:Bronchitis / Q000453:epidemiology / Q000821:virology; D015984:Causality; D015897:Comorbidity; D003428:Cross Infection / Q000453:epidemiology / Q000821:virology; D005260:Female; D005853:Geriatrics / Q000706:statistics & numerical data; D006301:Health Services Needs and Demand; D006748:Hospital Departments / Q000706:statistics & numerical data; D006801:Humans; D009980:Influenza A virus; D009981:Influenza B virus; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology; D007297:Inpatients / Q000706:statistics & numerical data*; D017563:Lung Diseases, Interstitial / Q000453:epidemiology / Q000821:virology; D008297:Male; D010297:Paris / Q000453:epidemiology; D010343:Patient Admission / Q000706:statistics & numerical data*; D011024:Pneumonia, Viral / Q000453:epidemiology / Q000821:virology; D011159:Population Surveillance; D018357:Respiratory Syncytial Virus Infections / Q000453:epidemiology* / Q000821:virology; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000821:virology; D012621:Seasons