Gastroprotective effect of nonstarch polysaccharide calcium pectate under experimental conditions.
Course prophylactic administration and single therapeutic treatment with calcium pectate improved resistance of rat gastroduodenal mucosa to ethanol-induced ulcers, prednisolone-induced ulcers, and H. Shay ulceration of the gastric mucosa.
Krylova
S G
SG
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences Russia.
Efimova
L A
LA
Zueva
E P
EP
Khotimchenko
M U
MU
Amosova
E N
EN
Razina
T G
TG
Lopatina
K A
KA
Khotimchenko
U S
US
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology / Q000627:therapeutic use; D000431:Ethanol; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects* / Q000473:pathology; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D008297:Male; D010368:Pectins / Q000494:pharmacology* / Q000627:therapeutic use; D010437:Peptic Ulcer / Q000139:chemically induced / Q000188:drug therapy*; D051381:Rats; D016896:Treatment Outcome
D000897:Anti-Ulcer Agents; D000431:Ethanol; D010368:Pectins; C003181:polygalacturonic acid