Aggressive angiomyxoma of the vulva: a case report and review of the literature.
BACKGROUND
Aggressive angiomyxoma is a variant of myxoid neoplasms of the female pelvic soft parts. The term "aggressive" refers to the tumor's locally infiltrative and recurrent nature because distant metastases are rare.


METHODS
A 25-year-old woman presented with a 9-month history of an asymptomatic, polypoid mass arising from the right anterior labium minus. Histopathological and radiological examinations were consistent with a diagnosis of aggressive angiomyxoma. The patient was treated with a GnRH agonist followed by surgical excision.


CONCLUSIONS
We highlight the novel use of a GnRH agonist as a neoadjuvant to surgery in aggressive angiomyxoma to shrink the tumor preoperatively and decrease surgical morbidity.
Sereda
Danya
D
Service de Dermatologie, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada. dsereda@sympatico.ca
Sauthier
Philippe
P
Hadjeres
Rachid
R
Funaro
Deana
D
D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D005260:Female; D017273:Goserelin / Q000008:administration & dosage*; D006801:Humans; D009232:Myxoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
D018931:Antineoplastic Agents, Hormonal; D017273:Goserelin