title: Primary cutaneous diffuse large B-cell lymphoma (leg type) after renal allograft: case report and review of the literature.
abstract: We report a case of a 58-year-old man who presented with a rapidly growing proliferative lesion on the left lower limb, clinically resembling a soft tissue sarcoma 3 years after renal allograft. There was no evidence of systemic involvement on bone marrow needle aspiration and computed tomography (CT) scans of the chest and abdomen. The lesion turned out to be primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT), as defined in the recent World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification of cutaneous lymphomas by skin biopsy. Immunosuppression reduction, chemotherapy with CHOP regimen and local radiotherapy induced complete remission of the tumor.
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China. hanbing_li@sina.com.
authors.forename: Bing
authors.initials: B
authors.lastname: Han
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Ti
authors.initials: T
authors.lastname: Shen
authors.affiliation: Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Yongqiang
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Fang
authors.affiliation: Department of Pathology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Dingrong
authors.initials: D
authors.lastname: Zhong
authors.affiliation: Department of Pathology, Peking Union Medical College Hospital, 100730, Beijing, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Ling
mesh_terms: D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D007866:Leg / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012074:Remission Induction / Q000379:methods; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology