title: [Clinical analysis of post pancreatoduodenectomy hemorrhage].
abstract: OBJECTIVE
  To explore the factors of post pancreatoduodenectomy hemorrhage.
  
  
  METHODS
  The clinical data of 263 cases between January 1998 and April 2008 underwent pancreatoduodenectomy were analyzed prospectively.
  
  
  RESULTS
  The overall mortality rate was 4.94% (13/263). Postoperative bleeding occurred in 23 patients (8.75%), with 8 episodes ending fatally (34.8%). The tumor size, Child classification, caput total resection and pancreatic leakage were identified as significant risk factors for post pancreatoduodenectomy hemorrhage by means of univariate analysis. The multivariate Logistic regression analysis revealed that all of the five factors turned out to be the independent risk factors.
  
  
  CONCLUSIONS
  The prevention of these bleeding complications depends in the first place on meticulous hemostatic technique. The pancreatic leakage is also one of the most important factors due to postoperative bleeding. The prophylactic use of somatostatin is not necessary.
authors.affiliation: Department of General Surgery, First Hospital, Peking University, Beijing 100034, China.
authors.forename: Song
authors.initials: S
authors.lastname: GAO
authors.forename: Yin-mo
authors.initials: YM
authors.lastname: YANG
authors.forename: Meng-shan
authors.initials: MS
authors.lastname: CAI
authors.forename: Wen-han
authors.initials: WH
authors.lastname: WU
authors.forename: Zhan-bing
authors.initials: ZB
authors.lastname: LIU
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhuang
authors.forename: Jian-xun
authors.initials: JX
authors.lastname: ZHAO
authors.forename: Yuan-lian
authors.initials: YL
authors.lastname: WAN
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016577:Pancreaticoduodenectomy; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors