title: Hepatocellular carcinoma with spontaneous regression: report of the rare case.
abstract: Spontaneous regression of a malignant tumor, including hepatocellular carcinoma, is extremely rare. A 78-year-old female with hepatitis B presented with a hepatocellular carcinoma, 3 cm in size, in the lateral segment. During her work-up before surgery, over the period of a month, the tumor started to show spontaneous regression from the radiological and biochemical studies. A lateral segmentectomy of the liver was performed, and the pathologic study showed complete necrosis of the tumor with vigorous inflammatory cellular infiltration. The patient is now doing well without any evidence of recurrence. We herein report a case with hepatocellular carcinoma showing spontaneous regression, and review the associated literature.
authors.affiliation: Department of Surgery, Institute of Health Biosciences, the University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Arakawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Mori
authors.forename: Toru
authors.initials: T
authors.lastname: Ikegami
authors.forename: Jun
authors.initials: J
authors.lastname: Hanaoka
authors.forename: Mami
authors.initials: M
authors.lastname: Kanamoto
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Kanemura
authors.forename: Yuji
authors.initials: Y
authors.lastname: Morine
authors.forename: Satoru
authors.initials: S
authors.lastname: Imura
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shimada
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000503:physiopathology*; D012075:Remission, Spontaneous