Skull base invasion of adenoid cystic carcinoma of the lacrimal gland : a case report.
Although adenoid cystic carcinoma (ACC) of the lacrimal gland is a rarely encountered orbital tumor, it invades intracranially more frequently than carcinomas of other glands in the head and neck. A 52-year-old man underwent orbital exenteration and resection of intracranially extended tumor via a fronto-orbito-zygomatic approach in combination with a transfacial approach. Histopathologically, the tumor showed perineural, vascular, and lymphatic invasion. Additionally, he received radiotherapy (60 Gy) and adjuvant systemic cisplatin and 5-fluorouracil chemotherapy due to residual tumor in the orbit and systemic metastases (lung, ribs, and spines). He was free of progression and recurrence at 6 months after treatment. The authors report a case of skull base invasion by an ACC of the lacrimal gland to remind neurosurgeons planning intervention that this disease shows a tendency to invade intracranially.
Lee
Jae Il
JI
Department of Neurosurgery, Masan Samsung Hospital, Sungkyunkwan University, School of Medicine, Masan, Korea.
Kim
Young Zoon
YZ
Lee
Eun Hee
EH
Kim
Kyu Hong
KH