Antibacterial activity and chemical constitutions of essential oils of Thymus persicus and Thymus eriocalyx from west of Iran.
The essential oils of Thymus persicus and Thymus eriocalyx were collected in Lorestan province, west of Iran and were examined by GC/MS and bacteriological tests. Twenty seven compounds representing 92.095% of T. persicus and 99.77% of Thymus eriocalyx essential oils were identified. The major constituents of T. persicus were thymol (10.71%), carvacrol (25.71%), gamma-terpinene (5.63%), alpha-pinene (1.14%), beta-pinene (1.02%), limonene (11.65%) trans-sabinene hydrate (7.78%) and 1-borneol (4.07%) and the major compounds of T. eriocalyx. were 1, 8-cinole (3.07%), L-linalool (1.01%), thymol (66.34%), caryophyllene oxide (2.96%) and carvacrol (7.5%). The oils also were examined for antibacterial activities against 6 standard bacteria by the broth microdilution and disc diffusion methods. They exhibited significant antibacterial activities against Staphylococcus aureus (MIC =1 : 235, MBC =1:20), Escherichia coli (MIC = 1:320, MBC =1:80) and Pseudomonas aeroginosa (MIC = MBC = 1:1280). The results were compared with control antibiotics.
Talei
Gholam Reza
GR
Department of Microbiology, Research Building, Lorestan University of Medical Sciences, Razi Street, Khoramabad P.O. Box 68198, Iran.
Meshkatalsadat
Mohammad Hadi
MH
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004926:Escherichia coli / Q000378:metabolism; D007492:Iran; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000378:metabolism*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000378:metabolism; D013211:Staphylococcus aureus / Q000378:metabolism; D046930:Thymus Plant / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D002939:Ciprofloxacin