title: Relations between systolic and diastolic function in children with dilated and hypertrophic cardiomyopathy as assessed by tissue Doppler imaging.
abstract: BACKGROUND
  The aim of this study was to investigate relations between longitudinal peak systolic tissue velocity (S') and early diastolic tissue velocity (E') in children with dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM).
  
  
  METHODS
  S' and E' were recorded by tissue Doppler at the lateral (mitral) annulus and basal ventricular septum in 148 children (age range, 0-18 years), 34 with DCM, 60 with HCM, and 54 controls. Correlations between S' and E' and the S'/E' ratio were investigated, as well as relations to other functional indices.
  
  
  RESULTS
  In all groups, S' was correlated with E' at the lateral annulus and interventricular septum, but the relation and S'/E' ratio differed between groups. In patients with DCM, both S' and E' were decreased, whereas in those with HCM, E' was decreased, with smaller decreases in S'. The S'/E' ratio was correlated with indices of ventricular relaxation and filling.
  
  
  CONCLUSIONS
  In pediatric DCM and HCM, systolic and diastolic longitudinal function are related, possibly reflecting effects of systolic function on diastolic recoil.
authors.affiliation: Division of Pediatric Cardiology, The Labatt Family Heart Center, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Arshiya
authors.initials: A
authors.lastname: Mohammed
authors.forename: Luc
authors.initials: L
authors.lastname: Mertens
authors.forename: Mark K
authors.initials: MK
authors.lastname: Friedberg
mesh_terms: D000293:Adolescent; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003971:Diastole; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013223:Statistics as Topic; D013599:Systole