title: Effects of a nurse-managed program on hepatitis A and B vaccine completion among homeless adults.
abstract: BACKGROUND
  Hepatitis B virus (HBV) infection constitutes a major health problem for homeless persons. Ability to complete an HBV vaccination series is complicated by the need to prioritize competing needs, such as addiction issues, safe places to sleep, and food, over health concerns.
  
  
  OBJECTIVE
  The objectives of this study were to evaluate the effectiveness of a nurse-case-managed intervention compared with that of two standard programs on completion of the combined hepatitis A virus (HAV) and HBV vaccine series among homeless adults and to assess sociodemographic factors and risk behaviors related to the vaccine completion.
  
  
  METHODS
  A randomized, three-group, prospective, quasi-experimental design was conducted with 865 homeless adults residing in homeless shelters, drug rehabilitation sites, and outdoor areas in the Skid Row area of Los Angeles. The programs included (a) nurse-case-managed sessions plus targeted hepatitis education, incentives, and tracking (NCMIT); (b) standard targeted hepatitis education plus incentives and tracking (SIT); and (c) standard targeted hepatitis education and incentives only (SI).
  
  
  RESULTS
  Sixty-eight percent of the NCMIT participants completed the three-series vaccine at 6 months, compared with 61% of SIT participants and 54% of SI participants. NCMIT participants had almost 2 times greater odds of completing vaccination than those of participants in the SI program. Completers were more likely to be older, to be female, to report fair or poor health, and not to have participated in a self-help drug treatment program. Newly homeless White adults were significantly less likely than were African Americans to complete the vaccine series.
  
  
  CONCLUSIONS
  The use of vaccination programs incorporating nurse case management and tracking is critical in supporting adherence to completion of a 6-month HAV/HBV vaccine. The finding that White homeless persons were the least likely to complete the vaccine series suggests that programs tailored to address their unique cultural issues are needed.
authors.affiliation: School of Nursing, University of California Los Angeles, Los Angeles, CA 90095-1702, USA. anyamath@sonnet.ucla.edu
authors.forename: Adeline
authors.initials: A
authors.lastname: Nyamathi
authors.forename: Yihang
authors.initials: Y
authors.lastname: Liu
authors.forename: Mary
authors.initials: M
authors.lastname: Marfisee
authors.forename: Steven
authors.initials: S
authors.lastname: Shoptaw
authors.forename: Paul
authors.initials: P
authors.lastname: Gregerson
authors.forename: Sammy
authors.initials: S
authors.lastname: Saab
authors.forename: Barbara
authors.initials: B
authors.lastname: Leake
authors.forename: Darlene
authors.initials: D
authors.lastname: Tyler
authors.forename: Lillian
authors.initials: L
authors.lastname: Gelberg
mesh_terms: D000328:Adult; D019090:Case Management / Q000458:organization & administration; D016358:Contact Tracing; D005260:Female; D006506:Hepatitis A / Q000517:prevention & control*; D022362:Hepatitis A Vaccines; D006509:Hepatitis B / Q000517:prevention & control*; D017325:Hepatitis B Vaccines; D006703:Ill-Housed Persons / Q000193:education / Q000523:psychology / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D015141:Los Angeles; D008297:Male; D008875:Middle Aged; D009042:Motivation; D015999:Multivariate Analysis; D024802:Nurse's Role; D015403:Nursing Evaluation Research; D010342:Patient Acceptance of Health Care / Q000523:psychology / Q000706:statistics & numerical data; D010353:Patient Education as Topic / Q000458:organization & administration; D015397:Program Evaluation; D011446:Prospective Studies; D012309:Risk-Taking; D016037:Single-Blind Method; D012959:Socioeconomic Factors; D014611:Vaccination / Q000451:nursing / Q000523:psychology / Q000706:statistics & numerical data; D017778:Vaccines, Combined
chemical_list: D022362:Hepatitis A Vaccines; D017325:Hepatitis B Vaccines; D017778:Vaccines, Combined; C433226:twinrix