[The efficacy of preoperative portal vein embolization for extended hepatectomy: a meta-analysis].
OBJECTIVE
To investigate the clinical value of preoperative portal vein embolization (PVE) for extended hepatectomy.


METHODS
A comprehensive Pubmed, Medline and Ovid database search to identify all registered literature on portal vein embolization. Meta-analysis was performed to assess the result of PVE.


RESULTS
A total of 9 literatures provided data sufficiently enough for analysis involving in 494 patients. The results showed that postoperative liver failure was higher in the non-PVE group than the PVE group, but there was no difference in postoperative mortality between the PVE and non-PVE group; in sub-category analysis of hepatocellular carcinoma and liver metastasis of colorectal cancer, there was no difference in postoperative 1, 3 and 5-year survival rate between the PVE group and non-PVE group; 1 literature about liver metastasis of colorectal cancer show there was significant difference in postoperative metastasis between the PVE and non-PVE group; several patients after PVE didn't performed hepatectomy due to disease progress.


CONCLUSIONS
PVE is a safe and effective procedure to prevent postresection liver failure due to insufficient liver remnant, but surgeon should be cautious to choose the patient for PVE.
Zhao
Wen-yi
WY
Department of General Surgery, Ren Ji Hospital, Shanghai Jiao Tong University of Medicine, Shanghai 200127, China.
Luo
Meng
M
Sun
Yong-wei
YW
Xu
Qing
Q
Chen
Wei
W
Zhao
Gang
G
Wu
Zhi-yong
ZY
D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D017093:Liver Failure / Q000209:etiology / Q000517:prevention & control; D011169:Portal Vein; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care; D016019:Survival Analysis; D016896:Treatment Outcome