Pulse pressure--independent predictor of poor early outcome and mortality following ischemic stroke.
BACKGROUND
Pulse pressure (PP) in acute stroke may be related to the outcome. The link between PP in the first week following ischemic stroke and early outcome was assessed.


METHODS
We calculated mean PPs during the first 7 days after stroke onset in 1,677 patients. Poor outcome at hospital discharge was defined as a modified Rankin scale score of 3 or more points or death. Logistic regression was developed to evaluate PP as an independent predictor of early outcome.


RESULTS
For patients with poor outcomes the mean PP during the first week was higher than that for patients with non-poor outcomes. A logistic regression model confirmed that elevated mean PP was independently associated with poor outcome at discharge and 30-day mortality.


CONCLUSIONS
Elevated PP during the acute phase of ischemic stroke is an independent predictor of poor early outcome at hospital discharge and 30-day mortality.
Grabska
Katarzyna
K
2nd Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland. kgrabska7@wp.pl
Niewada
Maciej
M
Sarzyńska-Długosz
Iwona
I
Kamiński
Bogumił
B
Członkowska
Anna
A
D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D020521:Stroke / Q000175:diagnosis* / Q000401:mortality* / Q000503:physiopathology; D015996:Survival Rate