Synthesis of chromans via [3 + 3] cyclocoupling of phenols with allylic alcohols using a Mo/o-chloranil catalyst system.
The combination of a molybdenum complex (CpMoCl(CO)(3) or [CpMo(CO)(3)](2)) and o-chloranil was used as a catalyst in the [3 + 3] cyclocoupling of phenols and allylic alcohols under microwave heating conditions. Substituted chromans were selectively obtained in moderate to good isolated yields.
Yamamoto
Yoshihiko
Y
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152-8552, Japan.
Itonaga
Kouhei
K
D002703:Chloranil / Q000737:chemistry*; D002839:Chromans / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D008872:Microwaves; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D020005:Propanols / Q000737:chemistry*; D024505:Tocopherols / Q000138:chemical synthesis
D002839:Chromans; D009942:Organometallic Compounds; D010636:Phenols; D020005:Propanols; D002703:Chloranil; C006463:allyl alcohol; D008982:Molybdenum; D024505:Tocopherols