title: Application of response surface method for optimization of dispersive liquid-liquid microextraction of water-soluble components of Rosa damascena Mill. essential oil.
abstract: Dispersive liquid-liquid microextraction (DLLME) coupled with gas chromatography-mass spectrometry (GC-MS) was applied for the determination of Rose water constituents. The effective parameters such as volume of extraction and disperser solvents, temperature, and salt effect were inspected by a full factorial design to identify important parameters and their interactions. It showed that salt addition had no effect on the efficiency. Next, a central composite design was applied to obtain optimum point of the important parameters. The optimal condition was obtained as 37.0 microL for extractor, 0.42 mL for disperser and temperature for 48 degrees C. The main components that were extracted at the optimum point were benzeneethanol (24.87%), geraniol (23.07%), beta-citronellol (22.38%), nerol (8.48%), eugenol (5.98%) and linalool (5.62%).
authors.affiliation: School of Chemistry, University College of Science, University of Tehran, Tehran, Iran. sereshti@khayam.ut.ac.ir
authors.forename: Hassan
authors.initials: H
authors.lastname: Sereshti
authors.forename: Maryam
authors.initials: M
authors.lastname: Karimi
authors.forename: Soheila
authors.initials: S
authors.lastname: Samadi
mesh_terms: D000465:Algorithms; D000704:Analysis of Variance; D005591:Chemical Fractionation / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry; D009822:Oils, Volatile / Q000737:chemistry*; D028321:Plant Preparations / Q000032:analysis* / Q000737:chemistry; D027826:Rosa / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012995:Solubility; D012997:Solvents / Q000737:chemistry; D013696:Temperature
chemical_list: D009822:Oils, Volatile; D028321:Plant Preparations; D012997:Solvents