title: [Evaluation of tissue strain and strain rate imaging for left heart function in children with systemic lupus erythematosus].
abstract: OBJECTIVE
  To investigate the diagnostic value of the tissue strain imaging in myocardial dysfunction in children with systemic lupus erythematosus (SLE).
  
  
  METHODS
  24 patients with SLE and 32 healthy controls underwent conventional and tissue Doppler echocardiography. Peak strain and strain rate value during systolic and diastolic phases as well as E/A, LVFS, LVEF were measured in both SLE and the control group subjects.
  
  
  RESULTS
  The E/A, LVFS and LVEF did not significantly differ between SLE children and controls (P > 0.05). The systolic peak strains and strain rates of SLE children were lower than those of the controls but there was no significant difference (P > 0.05). The diastolic peak strains and strain rates of SLE children were significantly lower than those of the controls (P < 0.01). The diastolic peak strains and strain rates of anticardiolipin antibodies (aCL) positive children were significantly lower than the aCL negative ones (P < 0.05).
  
  
  CONCLUSIONS
  Strain and strain rate combined with aCL could sensitively detect myocardial dysfunction of children with SLE.
authors.affiliation: Department of Echocardiography, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Liang
authors.forename: Mei
authors.initials: M
authors.lastname: Zhu
authors.forename: Juan
authors.initials: J
authors.lastname: Feng
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left