title: Aorta larger than pulmonary artery in the fetal 3-vessel view.
abstract: OBJECTIVE
  Fetal great artery asymmetry may accompany congenital heart disease. The fetal echocardiographic 3-vessel view (3VV) allows assessment of the superior vena cava, ascending aorta (AA), and main pulmonary artery (MPA). Our aim was to determine the association of congenital heart disease in fetuses with an AA/MPA ratio of greater than 1.
  
  
  METHODS
  We electronically searched our fetal echocardiographic database for studies performed between March 2002 and January 2008 that showed 3VVs with AA/MPA ratios of greater than 1 and correlated the findings with the presence of congenital heart disease.
  
  
  RESULTS
  In 2797 fetal echocardiograms, we identified 31 fetuses with normal 4-chamber views showing AA/MPA ratios of greater than 1 in the 3VV. Of 31 fetuses, 25 (81%) had tetralogy of Fallot (ToF) or a ToF variant, and 6 (19%) had an aortic valve abnormality or isolated dilatation of the AA.
  
  
  CONCLUSIONS
  Screening obstetric fetal sonography showing a 3VV AA/MPA ratio of greater than 1 suggests congenital heart disease and indicates the need for comprehensive fetal echocardiography.
authors.affiliation: Children's Heart Center, Las Vegas, NV 89109, USA. rollins@childrensheartcenter.com
authors.forename: Robert C
authors.initials: RC
authors.lastname: Rollins
authors.forename: Ruben J
authors.initials: RJ
authors.lastname: Acherman
authors.forename: William J
authors.initials: WJ
authors.lastname: Castillo
authors.forename: William N
authors.initials: WN
authors.lastname: Evans
authors.forename: Humberto
authors.initials: H
authors.lastname: Restrepo
mesh_terms: D001011:Aorta / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods*