title: Here comes the sun: recognition of UV-damaged DNA.
abstract: The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) report the structure of the complex of DNA Damage-Binding Protein 1 (DDB1) and DDB2 bound to a DNA photodimer, providing critical insight into the repair of DNA damage caused by ultraviolet light.
authors.affiliation: Departments of Medicine and Biochemistry, CCSR1145, Division of Oncology, Stanford University Medical Center, Stanford, CA 94305-5151, USA.
authors.forename: Gilbert
authors.initials: G
authors.lastname: Chu
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
mesh_terms: D004260:DNA Repair; D006801:Humans; D011740:Pyrimidine Dimers / Q000378:metabolism; D013472:Sunlight; D014466:Ultraviolet Rays; D014983:Xeroderma Pigmentosum / Q000378:metabolism
chemical_list: D011740:Pyrimidine Dimers