Peutz-Jeghers syndrome with small intestinal malignancy and cervical carcinoma.
We report a case of 30-year-old woman with Peutz-Jeghers syndrome (PJS). Because of small intestinal obstruction, she received the small intestinal polypectomy in 2001, and the pathological diagnosis was Peutz-Jeghers polyp canceration (mucinous adenocarcinoma, infiltrating full-thickness of the intestine). The patient did not feel uncomfortable after 6 mo of chemotherapy and other management. We kept a follow-up study on her and found that she suffered from cervical cancer in 2007, with a pathological diagnosis of cervical adenosquamous carcinoma.The patient presented with typical features of PJS, but without a family history. The PJS accompanied with both small intestinal and cervical malignancies has not been reported so far in the world.
Li
Lian-Jie
LJ
Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Wang
Zhi-Qing
ZQ
Wu
Bao-Ping
BP
D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D018196:Carcinoma, Adenosquamous / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000175:diagnosis; D010580:Peutz-Jeghers Syndrome / Q000150:complications* / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000175:diagnosis