title: Chiral guanidine catalyzed enantioselective reactions.
abstract: Chiral guanidine catalysts share common characteristics such as high pK(a) values and dual hydrogen-bonding modes of activation, and high catalytic activities and enantioselectivities can often be achieved. The utilization of guanidines as catalysts has been growing at a steady pace. In the past few years, it has attracted tremendous attention through several landmark achievements. This article highlights the development of chiral guanidine catalysis in asymmetric synthesis.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
authors.forename: Dasheng
authors.initials: D
authors.lastname: Leow
authors.forename: Choon-Hong
authors.initials: CH
authors.lastname: Tan
mesh_terms: D002384:Catalysis; D006146:Guanidines / Q000737:chemistry*; D006860:Hydrogen Bonding; D008956:Models, Chemical; D013237:Stereoisomerism
chemical_list: D006146:Guanidines