[Fluoroquinolones in ophthalmology: indications and current use].
Fluoroquinolones are commonly used in ophthalmology, either for conjunctival infections or endophthalmitis. Use of these antibiotics requires good knowledge of the pharmacokinetic profile and adverse effects, and contraindications must be respected. Fluoroquinolones are useful in 2008 given their antibacterial spectrum, good ocular penetration, and the potential benefit of intravitreal injection.
Chiquet
C
C
Service d'Ophtalmologie, Hôpital Michallon, Université J. Fourier, CHU de Grenoble, Grenoble. cchiquet@chu-grenoble.fr
Labetoulle
M
M
D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002648:Child; D000075202:Contraindications; D004347:Drug Interactions; D024901:Drug Resistance, Multiple, Bacterial; D009877:Endophthalmitis / Q000188:drug therapy; D015818:Eye Infections, Bacterial / Q000188:drug therapy*; D005260:Female; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D007267:Injections; D007634:Keratitis / Q000188:drug therapy; D015948:Keratoplasty, Penetrating; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D014822:Vitreous Body
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones