title: Novel three-component route to diastereoselective synthesis of trisubstituted vinylphosphonates using phosphites, acetylenic esters, and aroyl chlorides.
abstract: Trisubstituted vinylphosphonates have been prepared via three-component reaction using phosphites, acetylenic esters, and aroyl chlorides in good yields. A variety of phosphites, activated acetylenes, and aroyl chlorides have been successfully employed in these reactions. In addition, three-component synthesis of vinylphosphonate provides exclusive E-olefin stereochemistry.
authors.affiliation: Department of Chemistry, Tarbiat Modares University, Tehran, Iran.
authors.forename: Sadegh
authors.initials: S
authors.lastname: Rostamnia
authors.forename: Abdolali
authors.initials: A
authors.lastname: Alizadeh
authors.forename: Long-Guan
authors.initials: LG
authors.lastname: Zhu
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D063065:Organophosphonates / Q000138:chemical synthesis*; D017905:Phosphites / Q000737:chemistry; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000138:chemical synthesis*
chemical_list: D000447:Aldehydes; D000480:Alkynes; D004952:Esters; D063065:Organophosphonates; D017905:Phosphites; D014753:Vinyl Compounds; C433467:vinylphosphonic acid