Seizure propagation in a patient with musicogenic epilepsy.
Musicogenic epilepsy (ME) is a condition in which seizures are triggered by music. We describe a novel investigation of the mechanisms of ME using noninvasive (ictal 2-flurodeoxyglucose (2-FDG) positron emission tomography (PET)) and invasive (subdural arrays and depth electrodes) methodology in one patient with ME. Ictal PET defined onsets in the right mesial temporal lobe. This was confirmed by intracranial electrode recordings, where there was onset in the right mesial temporal lobe, followed by sequential spread to the lateral temporal cortex, Heschel's gyrus, insula, and frontal lobes. Right temporal lobectomy resulted in Engel class 1 outcome.
Mehta
Ashesh D
AD
Department of Neurosurgery, North Shore Long Island Jewish Health System, New Hyde Park, NY 11040, USA. amehta@nshs.edu
Ettinger
Alan B
AB
Perrine
Kenneth
K
Dhawan
Vijay
V
Patil
Allam
A
Jain
Sanjay K
SK
Klein
Gad
G
Schneider
Steven J
SJ
Eidelberg
David
D
D001931:Brain Mapping; D004569:Electroencephalography; D020195:Epilepsy, Reflex / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010456:Peptides, Cyclic; D049268:Positron-Emission Tomography / Q000379:methods; D012640:Seizures / Q000503:physiopathology*; D055815:Young Adult
C515149:4-fluorobenozyl-glutamyl-cyclo(arginyl-glycyl-aspartyl-tyrosyl-lysyl)2; D010456:Peptides, Cyclic