title: Estimated prevalence and risk factor for age-related maculopathy.
abstract: OBJECTIVE
  To assess the estimate prevalence and risk factors for age-related maculopathy (ARM) in Seoul, Korea.
  
  
  METHODS
  We examined 9,530 subjects with, 40 years of age or older between January 2006 and December 2006 in Seoul, Korea. Subjects underwent fundus photography, clinical examinations (including blood analyses), and completed detailed questionnaires. Fundus images were graded according to definitions from the Wisconsin Age-Related Maculopathy Grading System.
  
  
  RESULTS
  ARM was present in 235 subjects, corresponding to an estimate prevalence of 2.46%. Hepatitis B infection (positive status for HBsAg and HBcAb), serum triglyceride levels and high density lipoprotein levels remained as significant risk factors after age-adjustment. Multivariate analyses showed that the prevalence of ARM was significantly higher in older subjects [odds ratio (OR) 1.134; 95% CI 1.114-1.154] and those who were seropositive for hepatitis B surface antigen (OR 2.566; 95% CI 1.519-4.335).
  
  
  CONCLUSIONS
  The estimated prevalence of ARM was 2.46%. Age and hepatitis B infection may increase the risk of ARM.
authors.affiliation: Department of Ophthalmology, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, Korea.
authors.forename: Mi In
authors.initials: MI
authors.lastname: Roh
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Suk Ho
authors.initials: SH
authors.lastname: Byeon
authors.forename: Hyoung Jun
authors.initials: HJ
authors.lastname: Koh
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Lee
authors.forename: Oh Woong
authors.initials: OW
authors.lastname: Kwon
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008075:Lipoproteins, HDL / Q000097:blood; D008268:Macular Degeneration / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008075:Lipoproteins, HDL; D014280:Triglycerides