title: [Expression of SleX in nasal epithelium with chronic rhinosinusitis].
abstract: OBJECTIVE
  To explore the expression of SleX in nasal epithelium in patients with chronic rhinosinusitis.
  
  
  METHODS
  Nine nasal epitheliums from patients with chronic rhinosinusitis and 7 normal controls were stained with SleX antibody by immunohistochemistry, and its expression were analyzed.
  
  
  RESULTS
  Both nasal epithelial cells and neutrophils expressed SleX. Nearly 88.9% nasal epithelium from patients with chronic rhinosinusitis expressed SleX while 14.3% in normal control. Expression of SleX in nasal epitheliums from patients with chronic rhinosinusitis were higher than that in normal control. There were significant difference between two groups.
  
  
  CONCLUSIONS
  Nasal epithelium from patients with CRS is highly expressed SleX. It may involve the occurrence of chronic rhinosinusitis.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, 130033, China.
authors.forename: Xuewei
authors.initials: X
authors.lastname: Zhu
authors.forename: Dongdong
authors.initials: D
authors.lastname: Zhu
authors.forename: Kewei
authors.initials: K
authors.lastname: Sun
authors.forename: Yusheng
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Dong
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000378:metabolism*; D009504:Neutrophils / Q000378:metabolism; D009844:Oligosaccharides / Q000032:analysis*; D000080506:Sialyl Lewis X Antigen; D012852:Sinusitis / Q000378:metabolism*; D055815:Young Adult
chemical_list: D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen