Melanoma prognostic factors found in the dermatopathology report.
Significant prognostic information is available in a routine melanoma dermatopathology report. Features that are enumerated in the pathology report and that portend a potentially poorer prognosis are older age, site (acral, head, neck), male sex, increasing Breslow tumor thickness, increasing Clark's level, ulceration, increasing number of mitoses, vertical growth phase, regression, absence of a host inflammatory response, increased tumor vascularity, angiotropism, vascular invasion, neurotropism, marked atypia, and satellite metastasis.
Payette
Michael J
MJ
Department of Dermatology, MC-6230, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA.
Katz
Marilyn
M
Grant-Kels
Jane M
JM
D049109:Cell Proliferation; D005260:Female; D006801:Humans; D007249:Inflammation; D008297:Male; D008545:Melanoma / Q000098:blood supply / Q000145:classification / Q000276:immunology / Q000473:pathology* / Q000556:secondary; D009361:Neoplasm Invasiveness; D009365:Neoplasm Regression, Spontaneous; D011379:Prognosis; D012878:Skin Neoplasms / Q000098:blood supply / Q000145:classification / Q000276:immunology / Q000473:pathology*