title: [Osmotic demyelination syndrome in Addison crisis and severe hyponatremia].
abstract: Acute adrenal insufficiency is a life threatening disease with dehydration, hypotension, cerebral dysfunction and gastrointestinal symptoms accompanied by low plasma sodium and high plasma potassium. Osmotic demyelination syndrome (ODS) can occur rarely following correction of plasma sodium. We describe a case with extremely low plasma sodium and subsequent development of ODS. Correction which is too slow may lead to cerebral oedema, brain stem herniation and low sodium encephalopathy. Correction which is too fast may cause ODS. The dilemma is accentuated by concomitant Addison crisis.
authors.affiliation: Skovvangsvej 60, 3. th., DK-8200 Arhus N. seba@studmed.au.dk
authors.forename: Signe Elisabeth Bødker
authors.initials: SE
authors.lastname: Andersen
authors.forename: Brian
authors.initials: B
authors.lastname: Stausbøl-Grøn
authors.forename: Torsten Bloch
authors.initials: TB
authors.lastname: Rasmussen
mesh_terms: D000224:Addison Disease / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D001921:Brain / Q000473:pathology; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D007010:Hyponatremia / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male