Changes in liver-related hospital admissions and hospital mortality among HIV-infected patients (1998 to 2005).
Liver-related disease has increased as a cause of hospitalization and in-hospital death in HIV-infected patients since the introduction of highly active antiretroviral therapy (HAART). Better clinical management of these diseases may contribute to decreasing their incidence. Admissions due to liver-related disease in HIV-infected patients in our institution increased from 2.9% in 1998-1999 to 11.3% in 2004-2005 (P = 0.001). In-hospital deaths due to this cause increased from 2.7% in 1998-1999 to 26% in 2002-2003 (P = 0.02), with a subsequent decrease to 22% in 2004-2005. Hospitalization of HIV-infected patients for liver-related disease continues to increase, whereas the rate of in-hospital deaths from this cause appears to have changed since 2003.
del Valle
José
J
Unidad de Enfermedades Infecciosas, Hospital Universitario de Valme, Seville, Spain.
Macías
Juan
J
Mira
José Antonio
JA
García-García
José Angel
JA
Gómez-Mateos
Jesús
J
Pineda
Juan Antonio
JA
D000293:Adolescent; D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D010343:Patient Admission / Q000706:statistics & numerical data / Q000639:trends*; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D055815:Young Adult