Rats, cats, and elephants, but still no unicorn: induced pluripotent stem cells from new species.
Two independent studies in this issue of Cell Stem Cell (Liao et al., 2009; Li et al., 2009) derive rat induced pluripotent stem cells (iPSCs). In one report, the method used results in rat and human iPSCs that exhibit phenotypic traits similar to mouse embryonic stem cells.
Trounson
Alan
A
California Institute for Regenerative Medicine, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000378:metabolism; D065150:Cellular Reprogramming / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D044127:Epigenesis, Genetic / Q000187:drug effects; D004847:Epithelial Cells / Q000166:cytology / Q000187:drug effects; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D006801:Humans; D039904:Pluripotent Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism
D004791:Enzyme Inhibitors