Expression of intracellular molecular apoptosis regulator Bcl-2 in the liver in isolated and combined exposure to 24-h illumination and industrial frequency magnetic field.
We studied the effect of isolated and combined exposure to 24-h illumination and industrial frequency magnetic field on the expression of intracellular molecular apoptosis regulator Bcl-2 in the liver. Previous experiments showed enhanced expression of Bcl-2 protein in liver cells in animals maintained under conditions of 24-h illumination, whereas exposure to industrial frequency magnetic field had practically no effect on this process. Under conditions of combined exposure to 24-h illumination and industrial frequency magnetic field, magnetic field partially suppressed the expression of Bcl-2 induced by 24-h illumination.
Borodin
Yu I
YI
Novosibirsk State Medical University, Federal Agency for Health Care and Social Development, Russia.
Michurina
S V
SV
Arkhipov
S A
SA
Belkin
A D
AD
Jurakovsky
I P
IP
D000818:Animals; D017209:Apoptosis / Q000528:radiation effects*; D002940:Circadian Rhythm; D004781:Environmental Exposure / Q000009:adverse effects; D007221:Industry; D008029:Lighting / Q000379:methods*; D008099:Liver / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects* / Q000648:ultrastructure; D008280:Magnetics / Q000379:methods*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D019253:Proto-Oncogene Proteins c-bcl-2