[Value of mfVEP test in pituitary tumors diagnosis].
OBJECTIVE
To evaluate the mfVEP test in detection of the optic nerve neuropathy in pituitary tumors.


METHODS
We examined 30 eyes of 15 patients with confirmed by MRI pituitary tumors (7 patients with macroadenomas and 8 patients with microadenomas). In all patients the routine ophthalmologic examination, multifocal visual evoked potentials (mfVEP) and standard static perimetry (central 24-2 threshold), were performed. The control group consisted of 30 eyes of 15 healthy persons.


RESULTS
In 53% (16/30) of eyes manifested changes in static perimetry and/or in mfVEP test. In 13% (4/30) of eyes abnormal static perimetry and mfVEP were simultaneously observed. The only mfVEP abnormalities were the most frequent feature and were observed in 30% (9/30) of eyes. Only abnormal static perimetry results were observed in 10% (3/10) of eyes. In those eyes in related areas of mfVEP recordings the mean peak-to-peak amplitude was significantly reduced compare to the control group. In mfVEP test statistically significant peak-to-peak amplitude reduction was observed in superotemporal quadrants in comparison to the control group (p < 0.009).


CONCLUSIONS
MfVEP can be useful test in the optic nerve dysfunction/ neuropathy diagnosis in patients with pituitary tumors.
Piekarska
Anna
A
Z Katedry i Kliniki Okulistyki Pomorskiej Akademii Medycznej w Szczecinie. annapiekarska26@interia.pl
Lubiński
Wojciech
W
Gosławski
Wojciech
W
Wieliczko
Wiesława
W
Syrenicz
Anhelli
A
Olszowski
Tomasz
T
Karczewicz
Danuta
D
D000236:Adenoma / Q000150:complications / Q000175:diagnosis*; D016022:Case-Control Studies; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis*; D011044:Poland; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D058609:Visual Field Tests; D014794:Visual Fields