title: Aggressive carcinoid tumors arising in the duodenum, ileum, and rectum with liver metastasis: a report of three cases.
abstract: Three aggressive carcinoid tumors with liver metastasis arising in the duodenum (Case 1, 72-year-old man), ileum (Case 2, 72-year-old man), and rectum (Case 3, 67-year-old woman) were studied. Case 1 initially suffered from hemorrhage from an exophytic large tumor and developed a liver metastasis after operation. Cases 2 and 3 first presented as multiple liver metastases. Case 3 had a small submucosal tumor and showed a relatively high cell proliferation activity. Neoplastic cells expressed gastrin in Case 1, serotonin in Case 2, and did not express several peptides in Case 3.
authors.affiliation: Mito Saiseikai General Hospital, 3-3-10 Futabadai, Mito, Ibaraki 311-4198, Japan. oka-k@gb3.so-net.ne.jp
authors.forename: Kuniyuki
authors.initials: K
authors.lastname: Oka
authors.forename: Futoshi
authors.initials: F
authors.lastname: Hirai
authors.forename: Shigenori
authors.initials: S
authors.lastname: Nagakura
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Saito
authors.forename: Takashi
authors.initials: T
authors.lastname: Nihei
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yatabe
mesh_terms: D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology*; D004379:Duodenal Neoplasms / Q000473:pathology*; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D012004:Rectal Neoplasms / Q000473:pathology*