title: Attempts to quit smoking and relapse: factors associated with success or failure from the ATTEMPT cohort study.
abstract: OBJECTIVE
  To identify predictors of attempts to stop smoking and predictors of relapse.
  
  
  METHODS
  This study included 2431 smokers from pre-existing Internet panels in the United States, United Kingdom, Canada, France, and Spain. These panel members are Internet users who have registered voluntarily and agreed to participate in various online research studies. Respondents were aged 35-65 years, smoked >or= five cigarettes per day and intended to stop smoking in the next 3 months. They were followed every 3 months for up to 18 months via Internet contact on measures relating to quit attempts, smoking status, motivation to quit, nicotine cue, weight and weight concern, health-related factors, withdrawal symptoms, and smoking cessation aids.
  
  
  RESULTS
  In this study, recent quit attempts strongly predicted future attempts, but also predicted subsequent relapse. Motivation to quit was predictive of future attempts but not of relapse/abstinence following the attempts. Relapse to smoking was associated with nicotine dependence, exposure to smoking cues, craving, withdrawal symptoms, and lack of smoking cessation aids.
  
  
  CONCLUSIONS
  The findings lend support to a model of cessation in which level of motivation to stop generates quit attempts but plays little role in relapse. Dependence, social smoking cues, and a recently failed quit attempt are important factors in relapse.
authors.affiliation: RTI Health Solutions, P.O. Box 12194 Research Triangle Park, NC 27709-2194, United States.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Zhou
authors.forename: James
authors.initials: J
authors.lastname: Nonnemaker
authors.forename: Beth
authors.initials: B
authors.lastname: Sherrill
authors.forename: Alicia W
authors.initials: AW
authors.lastname: Gilsenan
authors.forename: Florence
authors.initials: F
authors.lastname: Coste
authors.forename: Robert
authors.initials: R
authors.lastname: West
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D020407:Internet; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D055502:Secondary Prevention; D016540:Smoking Cessation / Q000379:methods / Q000523:psychology*; D013375:Substance Withdrawal Syndrome / Q000523:psychology*