Acute kidney injury in burns: a story of volume and inflammation.
Acute kidney injury occurs in approximately one-quarter to one-third of patients with major burn injury. Apart from the usual suspects - such as older age, severity of burn injury, sepsis and multiple organ dysfunction - volume overload probably has an important role in the pathogenesis of acute kidney injury.
Colpaert
Kirsten
K
Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium. kirsten.colpaert@ugent.be
Hoste
Eric A
EA
D058186:Acute Kidney Injury / Q000209:etiology / Q000503:physiopathology*; D002056:Burns / Q000150:complications*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D015599:Trauma Severity Indices