[Endogenous anticonvulsants: neuropeptide Y and delta sleep inducing peptide].
BACKGROUND
The same neuropeptides regulate both cicle sleep-wake and excitability of the brain.


CONCLUSIONS
Literature data together with our results support the idea that delta sleep--inducing peptide and neuropeptide Y could represent one of the factors of the endogenous stabilization of brain excitability and potent antiepileptic in generalized metaphit-induced audiogenic convulsive activity. The same holds true for DSIP analogues.
Stanojlović
Olivera
O
Institut za medicinsku fiziologiju, Medicinski fakultet, Beograd. maxol@eunet.yu
Hrncić
Dragan
D
Radosavljević
Tatjana
T
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology; D001921:Brain / Q000502:physiology; D002940:Circadian Rhythm; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology / Q000502:physiology*; D004827:Epilepsy / Q000503:physiopathology; D006801:Humans; D009478:Neuropeptide Y / Q000494:pharmacology / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology*
D000927:Anticonvulsants; D009478:Neuropeptide Y; D018377:Neurotransmitter Agents; D003701:Delta Sleep-Inducing Peptide