title: Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst.
abstract: Organocatalysts for the asymmetric reduction of ketimines are presented that function well at low catalyst loadings providing chiral amines in good yield and enantioselectivity, the latter appearing to be independent of the ketimine substrate geometry.
authors.affiliation: Department of Chemistry, University of Sheffield, Dainton Building, Brook Hill, Sheffield, UKS3 7HF. simon.jones@sheffield.ac.uk.
authors.forename: François-Moana
authors.initials: FM
authors.lastname: Gautier
authors.forename: Simon
authors.initials: S
authors.lastname: Jones
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Martin
mesh_terms: D002384:Catalysis; D007093:Imidazoles / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007093:Imidazoles; D007097:Imines; D017646:Organosilicon Compounds; D012821:Silanes; C065893:trichlorosilane