title: Sustained benzodiazepine use in a community sample of older adults.
abstract: OBJECTIVE
  To identify factors associated with sustained benzodiazepine use in older adults.
  
  
  METHODS
  Twelve-year cohort study.
  
  
  METHODS
  Community-based epidemiological survey.
  
  
  METHODS
  One thousand three hundred forty-two individuals aged 65 and older.
  
  
  METHODS
  Demographics, medication use, depressive symptoms, sleep complaints, alcohol use, and smoking assessed at 2-year intervals; descriptive analysis to characterize benzodiazepine users and identify factors associated with sustained benzodiazepine use (use at two consecutive waves); and longitudinal lag-time analysis to determine characteristics that predicted sustained use.
  
  
  RESULTS
  Initially, 5.5% of men and 9.8% of women were using benzodiazepines. Users were significantly more likely than nonusers to be female and less educated, report more depressive and anxiety symptoms, use more prescription medications, have lower self-rated health, have difficulty maintaining sleep, and be less likely to consume alcohol. Approximately 50%, 44%, and 25% of these users aged 65 to 74, 75 to 84, and 85 and older, respectively, were sustained users at follow-up. Being female, using two or more nonbenzodiazepine prescription medications, and smoking were independently associated with subsequent sustained benzodiazepine use.
  
  
  CONCLUSIONS
  At the population level, women, smokers, and users of at least two prescription drugs have higher probabilities of sustaining benzodiazepine use once started. This information can facilitate risk assessment and counseling of older adults before prescribing benzodiazepines.
authors.affiliation: Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsbrgh, Pennsylvania, USA.
authors.forename: Keith R
authors.initials: KR
authors.lastname: Stowell
authors.forename: Chung-Chou H
authors.initials: CC
authors.lastname: Chang
authors.forename: Jonivander
authors.initials: J
authors.lastname: Bilt
authors.forename: Gary P
authors.initials: GP
authors.lastname: Stoehr
authors.forename: Mary
authors.initials: M
authors.lastname: Ganguli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001569:Benzodiazepines / Q000627:therapeutic use*; D015331:Cohort Studies; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D001569:Benzodiazepines