Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases.
Papillary glioneuronal tumors are a newly recognized type of brain neoplasm characterized by prominent pseudopapillary structures and glioneuronal elements. All prior cases have shown that these tumors have an indolent course. The authors present 2 patients with an aggressive variant of the tumor. The first patient had dissemination of her tumor and the second had local spreading. Therefore, the authors conclude that papillary glioneuronal tumors do not always behave in a strictly benign fashion.
Javahery
Ramin J
RJ
Division of Neurosurgery, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Davidson
Laurence
L
Fangusaro
Jason
J
Finlay
Jonathan L
JL
Gonzalez-Gomez
Ignacio
I
McComb
J Gordon
JG
D000293:Adolescent; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D002540:Cerebral Cortex / Q000473:pathology / Q000601:surgery*; D002648:Child; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000473:pathology / Q000601:surgery*; D018303:Ganglioglioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D018193:Neoplasms, Complex and Mixed / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012086:Reoperation; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin