title: Superficial granulomatous pyoderma treated preoperatively with infliximab.
abstract: We report a case of superficial granulomatous pyoderma (SGP) treated successfully with infliximab. A 71-year-old woman developed erythema, erosions and cribriform scarring in the right periorbital area following enucleation of the right eye. Histology showed three-layered granulomas typical of SGP. The patient's disease was unusual in that it failed to respond to a wide variety of immunosuppressants and this condition is rarely reported to affect the face. Eventually she was treated successfully with infliximab, enabling her to undergo extensive surgery despite the fact that her disease was pathergic in onset.
authors.affiliation: Department of Dermatology, Maxillofacial Surgery, St George's Hospital, London, UK. vakhras@sgul.ac.uk
authors.forename: V
authors.initials: V
authors.lastname: Akhras
authors.forename: R
authors.initials: R
authors.lastname: Sarkany
authors.forename: S
authors.initials: S
authors.lastname: Walsh
authors.forename: N
authors.initials: N
authors.lastname: Hyde
authors.forename: R A
authors.initials: RA
authors.lastname: Marsden
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D000069285:Infliximab; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal; D003879:Dermatologic Agents; D000069285:Infliximab