Antibiotic resistance in urinary isolates of Escherichia coli from college women with urinary tract infections.
Of 176 urine isolates from female students positive for Escherichia coli, 29.6% were trimethoprim-sulfamethoxazole resistant and none were nitrofurantoin resistant. Among students with a history of urinary tract infection (UTI) (n = 119), resistance to ciprofloxacin was 11.8%, compared to 1.8% among those without prior UTI. Nitrofurantoin should be considered for empirical therapy of lower tract UTI.
Olson
Ronald P
RP
Duke Student Health, Duke University, Durham, North Carolina 27710, USA. olson012@mc.duke.edu
Harrell
Lizzie J
LJ
Kaye
Keith S
KS
D000293:Adolescent; D000328:Adult; D002939:Ciprofloxacin / Q000494:pharmacology / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D009582:Nitrofurantoin / Q000494:pharmacology / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000235:genetics; D055815:Young Adult
D002939:Ciprofloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D009582:Nitrofurantoin