title: Transcriptional and posttranslational modifications of titin: implications for diastole.
authors.forename: Attila
authors.initials: A
authors.lastname: Borbély
authors.forename: Loek
authors.initials: L
authors.lastname: van Heerebeek
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Paulus
mesh_terms: D017398:Alternative Splicing; D000818:Animals; D064211:Connectin; D017868:Cyclic AMP-Dependent Protein Kinases / Q000502:physiology*; D017869:Cyclic GMP-Dependent Protein Kinases / Q000502:physiology*; D048909:Diabetes Complications / Q000378:metabolism / Q000473:pathology; D003931:Diacetyl / Q000031:analogs & derivatives / Q000494:pharmacology; D003971:Diastole / Q000502:physiology*; D004548:Elasticity; D005109:Extracellular Matrix / Q000648:ultrastructure; D018260:Gelsolin / Q000494:pharmacology; D054144:Heart Failure, Diastolic / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D051379:Mice; D009124:Muscle Proteins / Q000378:metabolism*; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D010766:Phosphorylation; D020033:Protein Isoforms / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D051381:Rats; D012518:Sarcomeres / Q000648:ultrastructure; D014284:Triiodothyronine / Q000502:physiology; D020257:Ventricular Remodeling / Q000502:physiology
chemical_list: D064211:Connectin; D018260:Gelsolin; D009124:Muscle Proteins; D020033:Protein Isoforms; C577285:TTN protein, human; C577295:Ttn protein, rat; D014284:Triiodothyronine; C004717:diacetylmonoxime; D011494:Protein Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D017869:Cyclic GMP-Dependent Protein Kinases; D003931:Diacetyl