title: [Genotypes of hepatitis B virus in Henan Luohe area].
abstract: OBJECTIVE
  To determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area.
  
  
  METHODS
  Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3.
  
  
  RESULTS
  About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree.
  
  
  CONCLUSIONS
  The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.
authors.affiliation: Luohe Medical College, Luohe 462002, China.
authors.forename: Fu-Qing
authors.initials: FQ
authors.lastname: Wang
authors.forename: Xiao-Lei
authors.initials: XL
authors.lastname: Huang
authors.forename: Ai-Qin
authors.initials: AQ
authors.lastname: Li
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Wang
authors.forename: Fu-Hua
authors.initials: FH
authors.lastname: Zhang
authors.forename: Yan-Bing
authors.initials: YB
authors.lastname: Cui
authors.forename: Yao
authors.initials: Y
authors.lastname: Yi
authors.forename: Si-Yong
authors.initials: SY
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D005838:Genotype; D006509:Hepatitis B / Q000821:virology*; D006514:Hepatitis B Surface Antigens / Q000097:blood / Q000235:genetics; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens