title: Cation-pi interactions at the active site of factor Xa: dramatic enhancement upon stepwise N-alkylation of ammonium ions.
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, Hönggerberg, HCI, 8093 Zürich, Switzerland.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Salonen
authors.forename: Christoph
authors.initials: C
authors.lastname: Bucher
authors.forename: David W
authors.initials: DW
authors.lastname: Banner
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Haap
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Mary
authors.forename: Jörg
authors.initials: J
authors.lastname: Benz
authors.forename: Olivier
authors.initials: O
authors.lastname: Kuster
authors.forename: Paul
authors.initials: P
authors.lastname: Seiler
authors.forename: W Bernd
authors.initials: WB
authors.lastname: Schweizer
authors.forename: François
authors.initials: F
authors.lastname: Diederich
mesh_terms: D000478:Alkylation; D000814:Aniline Compounds / Q000737:chemistry*; D020134:Catalytic Domain; D002412:Cations / Q000737:chemistry; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000737:chemistry; D015951:Factor Xa / Q000737:chemistry*; D065427:Factor Xa Inhibitors; D008024:Ligands; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D000814:Aniline Compounds; D002412:Cations; D004791:Enzyme Inhibitors; D065427:Factor Xa Inhibitors; D008024:Ligands; D000644:Quaternary Ammonium Compounds; D015951:Factor Xa