A proposal for a convenient notation for P-chiral nucleotide analogues. Part 4. A relationship between the Dp/Lp notation and stereochemistry of reactions.
Recently, we have proposed a new D(P)/L(P) stereochemical notation for P-chiral dinucleoside monophosphate analogues based on a structural relationship between compounds. As an extension of this work, we present here applications of the D(P)/L(P) notation for tracking stereochemistry of reaction pathways involving H-phosphonate, phosphoramidite, phosphorotriester, and other intermediates frequently met in the nucleotide chemistry.
Sobkowski
Michal
M
Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland. msob@ibch.poznan.pl
Stawinski
Jacek
J
Kraszewski
Adam
A
D001669:Biochemical Phenomena; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry*; D013237:Stereoisomerism; D009626:Terminology as Topic
D009705:Nucleosides; D009711:Nucleotides