[Expression of SleX in nasal epithelium with chronic rhinosinusitis].
OBJECTIVE
To explore the expression of SleX in nasal epithelium in patients with chronic rhinosinusitis.


METHODS
Nine nasal epitheliums from patients with chronic rhinosinusitis and 7 normal controls were stained with SleX antibody by immunohistochemistry, and its expression were analyzed.


RESULTS
Both nasal epithelial cells and neutrophils expressed SleX. Nearly 88.9% nasal epithelium from patients with chronic rhinosinusitis expressed SleX while 14.3% in normal control. Expression of SleX in nasal epitheliums from patients with chronic rhinosinusitis were higher than that in normal control. There were significant difference between two groups.


CONCLUSIONS
Nasal epithelium from patients with CRS is highly expressed SleX. It may involve the occurrence of chronic rhinosinusitis.
Zhu
Xuewei
X
Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, 130033, China.
Zhu
Dongdong
D
Sun
Kewei
K
Wang
Yusheng
Y
Dong
Zhen
Z
D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000378:metabolism*; D009504:Neutrophils / Q000378:metabolism; D009844:Oligosaccharides / Q000032:analysis*; D000080506:Sialyl Lewis X Antigen; D012852:Sinusitis / Q000378:metabolism*; D055815:Young Adult
D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen