title: Post-last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia.
abstract: The first large-scale fine characterization of Tunisian H lineages clarifies that the post-Last glacial maximum expansion originating in Iberia not only led to the resettlement of Europe but also of North Africa. We found that 46% of 81 Tunisian H lineages subscreened for 1,580 bp in mtDNA coding region were affiliated with H1 and H3 subhaplogroups, which are known to have originated in Iberia. Although no signs of local expansion were detected, which would allow a clear dating of their introduction, the younger and less diverse Tunisian H1 and H3 lineages indicate Iberia as the radiating centre. Major contributions from historical migrations to this Iberian genetic imprint in Tunisia were ruled out by the mtDNA gene pool similarity between Berber/Arab/cosmopolitan samples and some "Andalusian" communities, settled by the descendents of the "Moors" who once lived in Iberia for 10 centuries (between 8th and 17th centuries), before being expelled to Tunisia.
authors.affiliation: Laboratory of Genetics Immunology and Human Pathology, Faculty of Sciences of Tunis, Tunisia.
authors.forename: Lotfi
authors.initials: L
authors.lastname: Cherni
authors.forename: Verónica
authors.initials: V
authors.lastname: Fernandes
authors.forename: Joana B
authors.initials: JB
authors.lastname: Pereira
authors.forename: Marta D
authors.initials: MD
authors.lastname: Costa
authors.forename: Ana
authors.initials: A
authors.lastname: Goios
authors.forename: Sabeh
authors.initials: S
authors.lastname: Frigi
authors.forename: Besma
authors.initials: B
authors.lastname: Yacoubi-Loueslati
authors.forename: Mohamed Ben
authors.initials: MB
authors.lastname: Amor
authors.forename: Abdelhakim
authors.initials: A
authors.lastname: Slama
authors.forename: António
authors.initials: A
authors.lastname: Amorim
authors.forename: Amel Ben Ammar
authors.initials: AB
authors.lastname: El Gaaied
authors.forename: Luísa
authors.initials: L
authors.lastname: Pereira
mesh_terms: D000704:Analysis of Variance; D017931:DNA Primers / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D004641:Emigration and Immigration; D014644:Genetic Variation; D005828:Genetics, Population; D005843:Geography; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D046448:Ice Cover; D025341:Principal Component Analysis; D017422:Sequence Analysis, DNA; D014416:Tunisia
chemical_list: D017931:DNA Primers; D004272:DNA, Mitochondrial