The role of lymphadenectomy in esophageal cancer.
Lymph node metastases are common in esophageal cancer and are associated with a poor prognosis. Resection and examination of 15-18 lymph nodes is required for adequate staging of esophageal cancer. Improved survival is associated with involvement of five or fewer nodes or lymph node ratio (LNR) of < 0.10-0.20. More extensive lymph node dissection during esophagectomy offers improved staging but may also provide therapeutic benefit in terms of control of locoregional disease and possibly improved overall survival.
Darling
Gail
G
University of Toronto, Toronto, Ontario, Canada. gail.darling@uhn.on.ca
D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis