[Chemical constituents of antibacterial activity fraction of Angelica polymorpha].
OBJECTIVE
To study chemical constituents of antibacterial activity fraction of Angelica polymorpha.


METHODS
Compounds were isolated by repeatedly silica gel column chromatography and recrystallization. Their structures were identified by physical and chemical evidences and spectral methods.


RESULTS
Seven compounds were obtained from the antibacterial activity fraction, their structures were elucidated as: bisabolangelone(I), isoimperatorin (II), oxypeucedanine(III), isooxypeucedanine(IV), oxypeucedanin hydrate(V), bergapten(VI), pabulenol(VII).


CONCLUSIONS
Bisabolangelone(I) is obtained from this plant for the first time. Compound (II)-(VII) belong to linear furanocourmarins.
Cai
Zheng-jun
ZJ
Hubei Key Laboratory of Natural Products Research and Development/College of Chemistry and Life Sciences China Three Gorges University, Yichang 443002, China.
Dan
Fei-jun
FJ
Cheng
Fan
F
Wang
Jun-zhi
JZ
Zou
Kun
K
D000078223:5-Methoxypsoralen; D029969:Angelica / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D005363:Ficusin / Q000737:chemistry / Q000302:isolation & purification; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification*; D008730:Methoxsalen / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D003374:Coumarins; D011564:Furocoumarins; D012717:Sesquiterpenes; C455067:bisabolangelone; C055542:isoimperatorin; C487397:pabulenol; D000078223:5-Methoxypsoralen; D005363:Ficusin; D008730:Methoxsalen