[A long-term survival case of metastatic breast cancer treated with trastuzumab and paclitaxel].
We report a long-term survival case of metastatic breast cancer treated with trastuzumab and paclitaxel. The patient was a 50-year-old female. She underwent left mastectomy with axillary lymphadenectomy for advanced breast cancer with liver metastases. Histological examination showed papillotublar carcinoma, f, T3, ly3, v2, N2 (24/34), histological grade III, ER (-), PgR (-), HER2 (3+). Trastuzumab and paclitaxel was performed. One year after the operation, any lesions of liver were not detected by CT and she was diagnosed as a complete response. No evidence of viable lesions has been found for 7 years. Breast cancer with liver metastases often could be a life threatening, and therefore an optimal chemotherapy should be applied as soon as possible. Trastuzumab and paclitaxel would be one of the optimal chemotherapies for HER2 positive breast cancer.
Ogino
Takayuki
T
Dept. of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases.
Komoike
Yoshifumi
Y
Ishitobi
Masato
M
Motomura
Kazuyoshi
K
Inaji
Hideo
H
Koyama
Hiroki
H
D000911:Antibodies, Monoclonal / Q000276:immunology / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000276:immunology / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D007167:Immunotherapy; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology / Q000556:secondary*; D008408:Mastectomy; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D000068878:Trastuzumab
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068878:Trastuzumab; D017239:Paclitaxel