title: Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis.
abstract: OBJECTIVE
  The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of 4% articaine and 2% lidocaine (both with 1:100,000 epinephrine) for buccal infiltration in patients experiencing irreversible pulpitis in maxillary posterior teeth.
  
  
  METHODS
  Forty patients with irreversible pulpitis in first premolar or first molar were divided into 4 study groups and received buccal infiltration of either 4% articaine or 2% lidocaine in a double-blind manner. Endodontic access was begun 5 minutes after solution deposition. Success was defined as no or mild discomfort (VAS recordings) during the endodontic procedure.
  
  
  RESULTS
  The success rate for maxillary buccal infiltration to produce pulpal anesthesia using articaine was 100% in first premolar and first molar, and for the lidocaine solution, success rate was 80% in first premolar and 30% in first molar. There was high significant difference between the articaine and lidocaine solutions (ANOVA; P < .001).
  
  
  CONCLUSIONS
  The efficacy of 4% articaine was superior to 2% lidocaine for maxillary buccal infiltration in posterior teeth.
authors.affiliation: Department of Conservative Dentistry, Tamilnadu Government Dental College and Hospital, Chennai-3, India. nbalaji_82@yahoo.com
authors.forename: Narasimhan
authors.initials: N
authors.lastname: Srinivasan
authors.forename: Mahendran
authors.initials: M
authors.lastname: Kavitha
authors.forename: Chandarasekaran S
authors.initials: CS
authors.lastname: Loganathan
authors.forename: Govindasamy
authors.initials: G
authors.lastname: Padmini
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental / Q000379:methods*; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001641:Bicuspid; D002355:Carticaine / Q000008:administration & dosage*; D002610:Cheek; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008437:Maxilla; D008963:Molar; D010147:Pain Measurement; D011446:Prospective Studies; D011671:Pulpitis / Q000628:therapy*; D012390:Root Canal Therapy; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002355:Carticaine