Subcutaneous phaeohyphomycosis caused by Exophiala xenobiotica in a non-Hodgkin lymphoma patient.
Phaeohyphomycosis is a rare fungal infection that is more commonly associated with immunocompromised patients. We present a case in which a 77-year-old woman with non-Hodgkin lymphoma developed subcutaneous phaeohyphomycosis caused by Exophiala xenobiotica. E. xenobiotica is a dematiaceous hyphomycete that was recently identified as a segregant of the E. jeanselmei complex. The patient was successfully treated with local excision of the lesions and post-surgical oral itraconazole. The latter was administered with the aim of preventing systemic dissemination in this immunocompromised patient.
Aoyama
Yumi
Y
Department of Dermatology, Gifu University Graduate School of Medicine, Gifu City, Japan. ymaoyama@gifu-u.ac.jp
Nomura
Masayo
M
Yamanaka
Shinya
S
Ogawa
Yoko
Y
Kitajima
Yasuo
Y
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D004271:DNA, Fungal / Q000032:analysis; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D005093:Exophiala / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006229:Hand Dermatoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D017422:Sequence Analysis, DNA
D000935:Antifungal Agents; D004271:DNA, Fungal; D017964:Itraconazole