title: Analysis of epileptic EEG signals using higher order spectra.
abstract: The unpredictability of the occurrence of epileptic seizures contributes to the burden of the disease to a major degree. An automatic system that detects seizure onsets would allow patients or the people near them to take appropriate precautions, and could provide more insight into these phenomena, thereby revealing important clinical information. Thus, various methods have been proposed to predict the onset of seizures based on EEG recordings. A seemingly promising approach involves nonlinear features motivated by the higher order spectra (HOS). The goal in this paper is to find the different HOS features for normal, pre-ictal (background) and epileptic EEG signals. This may help in the detection of seizure onset as early as possible with maximal accuracy. In this work, 300 EEG data, each belonging to the three classes, are studied. Our results show that the HOS based measures show unique ranges for the different classes with high confidence level (p = 0.002).
authors.affiliation: Division of Electronic and Computer Engineering, Ngee Ann Polytechnic, Singapore. ckc@np.edu.sg
authors.forename: K C
authors.initials: KC
authors.lastname: Chua
authors.forename: V
authors.initials: V
authors.lastname: Chandran
authors.forename: U Rajendra
authors.initials: UR
authors.lastname: Acharya
authors.forename: C M
authors.initials: CM
authors.lastname: Lim
mesh_terms: D000465:Algorithms; D000704:Analysis of Variance; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D012640:Seizures / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology