The p-bromodienone route to nucleophilic functionalization of calixarene exo rim.
Easily accessible calixarene p-bromodienone derivatives undergo a silver-mediated nucleophilic substitution and a subsequent rearomatization with a range of different O-nucleophiles (alcohols and carboxylates) to give p-alkoxy- or p-acyloxycalixarenes in workable yields. This approach can be considered a general "p-bromodienone route" to functionalize calixarene exo rim with nucleophiles.
Troisi
Francesco
F
Dipartimento di Chimica, Università di Salerno, Via Ponte don Melillo, I-84084 Fisciano (Salerno), Italy.
Pierro
Teresa
T
Gaeta
Carmine
C
Neri
Placido
P