title: POEMS syndrome: a case report.
abstract: A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation. The clinical evaluation met the criteria for the diagnosis of POEMS syndrome. The patient was initially treated with prednisolone and responded well. We planned high-dose chemotherapy with autologous stem cell rescue and introduced a more immunosuppressive regimen containing cyclophosphamide and dexamethasone. We present a case differing from the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.
authors.affiliation: Departments of Gastroenterology School of Medicine, Ankara University, Ankara. drokocaman@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Ozden
authors.forename: Zeygam
authors.initials: Z
authors.lastname: Süleyman
authors.forename: Gülseren
authors.initials: G
authors.lastname: Seven
authors.forename: Mutlu
authors.initials: M
authors.lastname: Arat
authors.forename: Alper
authors.initials: A
authors.lastname: Akin
authors.forename: Ozden
authors.initials: O
authors.lastname: Sener
authors.forename: Işinsu
authors.initials: I
authors.lastname: Kuzu
authors.forename: Kenan
authors.initials: K
authors.lastname: Keven
authors.forename: Arzu
authors.initials: A
authors.lastname: Ensari
authors.forename: Ayşe
authors.initials: A
authors.lastname: Erden
authors.forename: Ersin
authors.initials: E
authors.lastname: Tan
mesh_terms: D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016878:POEMS Syndrome / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003907:Dexamethasone; D003520:Cyclophosphamide