Cyclosporins from Mycelium sterilae MS 2929.
The structures of two new cyclosporins were elucidated by NMR and MS methods as cyclo[-MeBmt(1)-Abu(2)-Sar(3)-MeLeu(4)-Val(5)-MeLeu(6)-Ala(7)-d-Ala(8)-MeLeu(9)-MeNva(10)-MeVal(11)-] and cyclo[-MeBmt(1)-Abu(2)-Sar(3)-MeLeu(4)-Abu(5)-MeLeu(6)-Ala(7)-d-Ala(8)-MeLeu(9)-MeLeu(10)-MeVal(11)-].
Kuzma
Marek
M
Institute of Microbiology, Academy of Sciences of the Czech Republic, Vídenská 1083, 142 20 Prague, Czech Republic.
Sedmera
Petr
P
Jegorov
Alexandr
A
Havlícek
Vladimír
V
D000595:Amino Acid Sequence; D003524:Cyclosporins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005658:Fungi / Q000737:chemistry*; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014633:Valine / Q000031:analogs & derivatives / Q000737:chemistry
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D010456:Peptides, Cyclic; C005313:norvaline; D014633:Valine