Stereoselective formation of alkenyl halides via magnesium halide promoted ring opening of bis-activated cyclopropenes.
In the presence of stoichiometric magnesium halides, a range of bis-activated cyclopropenes undergo highly stereoselective ring-opening reactions to produce multisubstituted alkenyl halides. More highly functionalized compounds may be obtained by trapping of the magnesium enolate intermediates in situ.
Wang
Yi
Y
School of Chemistry, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh, EH9 3JJ, United Kingdom.
Lam
Hon Wai
HW