Eosinophil-rich inflammatory response to FloSeal hemostatic matrix presenting as postoperative pelvic pain.
FloSeal hemostatic matrix has been reported to be effective for the control of intraoperative bleeding in various surgeries. We report 3 patients who experienced a possible allergic response to FloSeal with the formation of excessive granulation tissue and fibrosis that were associated with early postoperative pelvic pain that led to additional surgical intervention.
Thomas
Priscilla J
PJ
Department of Pathology, University of Minnesota Medical Center, Fairview, Minneapolis, MN, USA.
Tawfic
Sherif N
SN
D000328:Adult; D004802:Eosinophilia / Q000209:etiology*; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000009:adverse effects*; D006489:Hemostatic Techniques / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D017699:Pelvic Pain / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology*
C411004:FloSeal Matrix