Cerebellar medulloblastoma in the elderly.
Although medulloblastoma is the most common central nervous system malignancy in children, cases are much less common in adults. Moreover, this tumor is exceedingly rare in patients older than 65 years. Analysis of previous case reports reveals that medulloblastoma in the elderly is more commonly seen in males in a lateral location; histologically, medulloblastomas in aged individuals usually belong to the classic subtype. During intraoperative consultation, the pathologist should consider medulloblastoma in the differential diagnosis of a cerebellar mass in the elderly because cytologic features may overlap with metastatic small cell carcinoma or lymphoma. We present a case of medulloblastoma in a 66-year-old man and review the literature on the subject.
Huppmann
Alison R
AR
Department of Pathology, The George Washington University Medical Center, Washington, DC 20037, USA. huppmann@gwu.edu
Orenstein
Jan M
JM
Jones
Robert V
RV
D000368:Aged; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008527:Medulloblastoma / Q000473:pathology* / Q000601:surgery