title: Bovine spongiform encephalopathy.
abstract: Bovine spongiform encephalopathy is an infectious disease of cattle that is transmitted through the consumption of meat-and-bone meal from infected cattle. The etiologic agent is an aberrant isoform of the native cellular prion protein that is a normal component of neurologic tissue. There currently are no approved tests that can detect BSE in live cattle.
authors.affiliation: Food Safety and Inspection Service, Office of Public Health Science, USDA, 1400 Independence Ave SW, Washington, DC 20250, USA.
authors.forename: Jane L
authors.initials: JL
authors.lastname: Harman
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Silva
mesh_terms: D000367:Age Factors; D000821:Animal Feed; D000818:Animals; D001688:Biological Products; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000209:etiology; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary; D016643:Encephalopathy, Bovine Spongiform / Q000453:epidemiology* / Q000473:pathology / Q000635:transmission*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008903:Minerals; D018620:PrPSc Proteins / Q000032:analysis; D012307:Risk Factors; D015047:Zoonoses
chemical_list: D001688:Biological Products; D008903:Minerals; D018620:PrPSc Proteins; C027762:bone meal