title: [Hepatic artery infusion chemotherapy to three liver metastasis cases in which systemic chemotherapy was impossible or ineffective].
abstract: Recently, standard therapies for either gastric cancer or colorectal cancer have been established through the development of multidrug systemic chemotherapy and the appearance of molecular targeting drugs. For example, either FOLFIRI or FOLFOX therapy is normally chosen for the treatment of unresectable liver metastasis from colorectal cancer. On the other hand, hepatic artery infusion (HAI) chemotherapy is generally used as only a second-line therapy. There are, however, some cases in which systemic chemotherapy is not indicated due to age and/or the risk of side effects. We herein report three cases that were treated by HAI after initially performing systemic chemotherapy in order to treat liver metastasis from either gastric cancer or colorectal cancer.
authors.affiliation: Dept. of Surgery and Science, Graduate School of Medical Sciences, Kyushu University.
authors.forename: Koji
authors.initials: K
authors.lastname: Ando
authors.forename: Eiji
authors.initials: E
authors.lastname: Oki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kakeji
authors.forename: Masahiko
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Saeki
authors.forename: Kazuya
authors.initials: K
authors.lastname: Endo
authors.forename: Masaru
authors.initials: M
authors.lastname: Morita
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Emi
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Maehara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002272:Carcinoembryonic Antigen / Q000097:blood; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D012004:Rectal Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D002272:Carcinoembryonic Antigen; D005472:Fluorouracil