Regulation of convergent extension by non-canonical Wnt signaling in the Xenopus embryo.
Non-canonical Wnt signaling is an important regulator of gastrulation in Xenopus. In particular, it has been implicated in the control of convergent extension movements. Convergent extension in the gastrula occurs primarily in the dorsal tissue of the marginal zone, and explants of this tissue will continue to undergo these movements in isolation. This observation has led to an assay to examine convergent extension movements that is unique to the Xenopus system, and is described herein.
Petersen
Lars F
LF
Department of Cell & Systems Biology, University of Toronto, Toronto, ON, Canada.
Ninomiya
Hiromasa
H
Winklbauer
Rudolf
R
D000818:Animals; D001681:Biological Assay / Q000379:methods*; D015398:Signal Transduction / Q000502:physiology*; D051153:Wnt Proteins / Q000235:genetics / Q000378:metabolism*; D029867:Xenopus Proteins / Q000235:genetics / Q000378:metabolism; D014982:Xenopus laevis / Q000196:embryology / Q000502:physiology
D051153:Wnt Proteins; D029867:Xenopus Proteins