Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication.
Aghi
Manish K
MK
Department of Neurological Surgery, University of California at San Francisco, San Francisco, California, USA.
Chiocca
E Antonio
EA
D000212:Acyclovir / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000097:blood; D001932:Brain Neoplasms / Q000188:drug therapy / Q000628:therapy*; D002986:Clinical Trials as Topic; D005909:Glioblastoma / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D018139:Simplexvirus / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D016896:Treatment Outcome; D014779:Virus Replication / Q000502:physiology*
D000914:Antibodies, Viral; D000212:Acyclovir