title: [Posterior polymorphous dystrophy--changes in corneal morphology in confocal microscopy].
abstract: OBJECTIVE
  To describe the in vivo conocal microscopic findings in posterior polymorphous dystrophy (PPD).
  
  
  METHODS
  Eleven patients (22 eyes) with PPD suspected or clinically diagnosed were examined using scanning slit white light confocal microscopy (ConfoScan 3, Nidek Technologies).
  
  
  RESULTS
  Endothelial cell densities ranged from 716 to 2380 cells/mm2 and endothelial polymegathism was noted in all cases. In 5 cases PPD changes was reported unilateral. Confocal microscopy demonstrated a variety of vesicular and linear abnormalities. In 13 eyes exhibited bright, nucleus-like structures within endothelial cells. Stromal edema was noted in 4 cases.
  
  
  CONCLUSIONS
  To our knowledge, we present the largest case series of PPD imaged by in vivo confocal microscopy. Confocal microscopy images of PPD are very characteristic. This method allows to confirm presumptive or to identify final diagnosis. Our study enhances the value of confocal microscopy in detection and monitoring corneal abnormalities.
authors.affiliation: Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Uniwersytetu Medycznego w Warszawie. jacek@amwaw.edu.pl
authors.forename: Jacek P
authors.initials: JP
authors.lastname: Szaflik
authors.forename: Urszula
authors.initials: U
authors.lastname: Kołodziejska
authors.forename: Monika
authors.initials: M
authors.lastname: Udziela
authors.forename: Wojciech
authors.initials: W
authors.lastname: Kołodziejczyk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Szaflik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002452:Cell Count; D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D003319:Corneal Stroma / Q000473:pathology; D019781:Corneal Topography / Q000295:instrumentation* / Q000379:methods; D003886:Descemet Membrane / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal / Q000379:methods; D008875:Middle Aged; D011044:Poland; D012680:Sensitivity and Specificity