title: [Comparison of DK crush with classical crush technique with drug-eluting stents for the treatment of coronary bifurcation lesions from DKCRUSH-1 study].
abstract: OBJECTIVE
  To determine independent factors correlated with clinical effects of DK crush and classical crush technique with drug-eluting stents on bifurcation lesions.
  
  
  METHODS
  311 patients with bifurcation lesions were randomized to classical (C, n = 156) or double kissing (DK) crush (n = 155) stent implantation group. The primary endpoints included major adverse cardiac events (MACE).
  
  
  RESULTS
  Final kissing balloon inflation (FKBI) success rate was 76% in C and 100% in DK groups (P < 0.001). DK crush procedure was characterized by lower unsatisfactory FKBI rate (27.6% vs.6.3%, P < 0.01). Clinical follow-up was available in 100% and angiographic follow-up in 82% patients. The overall restenosis rate was 32.3% in C and 20.3% in DK groups (P = 0.01), respectively. Cumulative 8-month MACE was 35.9% in without-FKBI and 19.7% in with-FKBI sub-groups, and 11.4% in DK group (P = 0.02). The incidence of stent thrombosis was 3.2% in C group (5.1% without vs. 1.7% with FKBI) and 1.3% in DK group (P > 0.05). The predictive factors of MACE included minimal side branch stent lumen diameter and lack of DK crush technique.
  
  
  CONCLUSIONS
  DK crush technique is an alternative of double stenting techniques in terms of improvement of restenosis and clinical outcomes.
authors.affiliation: Department of Cardiology, Nanjing First Hospital, Nanjing Medical College, Nanjing 210006, China. chmengx@126.com
authors.forename: Shao-liang
authors.initials: SL
authors.lastname: Chen
authors.forename: Jun-jie
authors.initials: JJ
authors.lastname: Zhang
authors.forename: Fei
authors.initials: F
authors.lastname: Ye
authors.forename: Yun-dai
authors.initials: YD
authors.lastname: Chen
authors.forename: Shu-zheng
authors.initials: SZ
authors.lastname: Lü
authors.forename: Huaycheem
authors.initials: H
authors.lastname: Tan
authors.forename: Tejas
authors.initials: T
authors.lastname: Patel
authors.forename: Kawajiri
authors.initials: K
authors.lastname: Kenji
authors.forename: Israel
authors.initials: I
authors.lastname: Tamari
authors.forename: Shou-jie
authors.initials: SJ
authors.lastname: Shan
authors.forename: Zhong-sheng
authors.initials: ZS
authors.lastname: Zhu
authors.forename: Song
authors.initials: S
authors.lastname: Lin
authors.forename: Nai-liang
authors.initials: NL
authors.lastname: Tian
authors.forename: Xiao-bo
authors.initials: XB
authors.lastname: Li
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Liu
authors.forename: Michael
authors.initials: M
authors.lastname: Lee
authors.forename: Meng
authors.initials: M
authors.lastname: Wei
authors.forename: Ya-wei
authors.initials: YW
authors.lastname: Xu
authors.forename: Zheng-bai
authors.initials: ZB
authors.lastname: Yuan
authors.forename: Jun
authors.initials: J
authors.lastname: Qian
authors.forename: Xue-wen
authors.initials: XW
authors.lastname: Sun
authors.forename: Song
authors.initials: S
authors.lastname: Yang
authors.forename: Jin-guo
authors.initials: JG
authors.lastname: Chen
authors.forename: Ben
authors.initials: B
authors.lastname: He
authors.forename: Suji
authors.initials: S
authors.lastname: Sumit
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D003324:Coronary Artery Disease / Q000628:therapy*; D023921:Coronary Stenosis / Q000628:therapy; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents