Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles.
OBJECTIVE
To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles.


METHODS
Case-control study.


METHODS
An IVF laboratory in a university hospital in Taiwan.


METHODS
Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group.


METHODS
None.


METHODS
Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer.


RESULTS
The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group.


CONCLUSIONS
A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.
Ou
Yu-Che
YC
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Niaosung Hsiang, Kaohsiung, Taiwan.
Lan
Kuo-Chung
KC
Huang
Fu-Jen
FJ
Kung
Fu-Tsai
FT
Lan
Ting-Hsun
TH
Chang
Shiuh Young
SY
D000328:Adult; D016022:Case-Control Studies; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007246:Infertility / Q000628:therapy*; D050498:Live Birth; D008297:Male; D008875:Middle Aged; D054315:Oocyte Retrieval; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D013624:Taiwan; D016896:Treatment Outcome