title: Effect of surgically induced weight loss on pelvic floor disorders in morbidly obese women.
abstract: OBJECTIVE
  To evaluate the effect of surgically induced weight loss on pelvic floor disorders (PFD) in morbidly obese women.
  
  
  BACKGROUND
  Although bariatric surgery may lead to the improvement of some obesity-related comorbidities, the resolution of global PFD has not been well described.
  
  
  METHODS
  Women with a body mass index (BMI) of 35 kg/m(2) or more who were considering bariatric surgery were asked to complete 2 validated condition-specific questionnaires assessing the distress/quality of life impact of PFD, total and by domain (pelvic organ prolapse, colorectal-anal, and urogenital). Women who achieved a > or =50% excess body weight loss after surgery were asked to complete the same questionnaires for comparison.
  
  
  RESULTS
  Of the 178 women who underwent surgery, 46 completed the postoperative questionnaires. Mean age of this group was 45 years (range, 20-67), and mean preoperative BMI was 45 kg/m(2) (range, 35-75). The prevalence of PFD symptoms improved from 87% before surgery to 65% after surgery (P = 0.02, 95% CI: 0.05%-53%). There was a significant reduction in total mean distress scores after surgery (P = 0.015, 95% CI: 3.3-32.9), which was attributed mainly to the significant decrease in urinary symptoms (P = 0.0002, 95% CI: 8.2-22.7). Reductions in the scores were noted for the other PFD domains as well. Quality of life total scores improved (P = 0.002, 95% CI: 4.8-27.1), as did scores in the urinary domain (P = 0.0005, 95% CI: 3.8-13.5) and the pelvic organ prolapse domain (P = 0.015, 95% CI: 0.6-9.5). Age, parity, history of complicated delivery, percent excess body weight loss, BMI, type of weight loss procedure and presence of diabetes mellitus and hypertension had no predictive value for postoperative outcomes.
  
  
  CONCLUSIONS
  Surgically induced weight loss has a beneficial effect on symptoms of PFD in morbidly obese women.
authors.affiliation: Division of Colorectal and Pelvic Floor Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. nwasserberg@gmail.com
authors.forename: Nir
authors.initials: N
authors.lastname: Wasserberg
authors.forename: Patrizio
authors.initials: P
authors.lastname: Petrone
authors.forename: Mark
authors.initials: M
authors.lastname: Haney
authors.forename: Peter F
authors.initials: PF
authors.lastname: Crookes
authors.forename: Howard S
authors.initials: HS
authors.lastname: Kaufman
mesh_terms: D000328:Adult; D000368:Aged; D050110:Bariatric Surgery; D005260:Female; D052776:Female Urogenital Diseases / Q000209:etiology; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000601:surgery*; D017773:Pelvic Floor; D011795:Surveys and Questionnaires; D015431:Weight Loss; D055815:Young Adult