[Free radical processes and erythron in pregnant rats and their fetuses in chronic nitrite intoxication].
The purpose of the investigation was to study changes in the intensity of induced chemiluminescence of serum and erythrocytes, as well as the erythrocytic system in pregnant rats and fetuses in chronic nitrite intoxication. In nitrite-intoxicated pregnant rats, the level of erythropenia was less than that in intact pregnant rats, fetuses being observed to have stimulated erythropoiesis. In intact pregnant animals, the intensity of induced chemiluminescence on day 20 was higher than the baseline and throughout the follow-up in nitrite-intoxicated adult animals and fetuses.
Ivanova
A S
AS
Sitnikova
O G
OG
Nazarov
S B
SB
D000818:Animals; D004912:Erythrocytes / Q000187:drug effects*; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000196:embryology / Q000378:metabolism*; D005500:Follow-Up Studies; D016166:Free Radical Scavengers / Q000378:metabolism*; D011086:Polycythemia / Q000139:chemically induced / Q000196:embryology / Q000378:metabolism*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000378:metabolism*; D051381:Rats; D012977:Sodium Nitrite / Q000633:toxicity*; D013997:Time Factors
D016166:Free Radical Scavengers; D012977:Sodium Nitrite