title: Rod and S-cone driven ERG signals at high retinal illuminances.
abstract: The purpose of the present study was to investigate whether L- and M-cone driven responses can be influenced by concomitant modulation in the rods or the S-cones. In addition, it was studied whether a change in the state of adaptation in L- or M-cones can have a different influence on ERG data when simultaneously the mean number of photoisomerizations in either rods or S-cones is altered. It was found that rods and/or S-cones cannot be neglected when measuring L- or M-cone driven ERGs.
authors.affiliation: Department of Ophthalmology, University Hospital Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany. jan.kremers@uk-erlangen.de
authors.forename: Jan
authors.initials: J
authors.lastname: Kremers
authors.forename: Dariusz
authors.initials: D
authors.lastname: Czop
authors.forename: Barbara
authors.initials: B
authors.lastname: Link
mesh_terms: D000328:Adult; D004596:Electroretinography; D005260:Female; D006801:Humans; D008029:Lighting; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000502:physiology*; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology*; D013997:Time Factors