Aggressive carcinoid tumors arising in the duodenum, ileum, and rectum with liver metastasis: a report of three cases.
Three aggressive carcinoid tumors with liver metastasis arising in the duodenum (Case 1, 72-year-old man), ileum (Case 2, 72-year-old man), and rectum (Case 3, 67-year-old woman) were studied. Case 1 initially suffered from hemorrhage from an exophytic large tumor and developed a liver metastasis after operation. Cases 2 and 3 first presented as multiple liver metastases. Case 3 had a small submucosal tumor and showed a relatively high cell proliferation activity. Neoplastic cells expressed gastrin in Case 1, serotonin in Case 2, and did not express several peptides in Case 3.
Oka
Kuniyuki
K
Mito Saiseikai General Hospital, 3-3-10 Futabadai, Mito, Ibaraki 311-4198, Japan. oka-k@gb3.so-net.ne.jp
Hirai
Futoshi
F
Nagakura
Shigenori
S
Saito
Hidetoshi
H
Nihei
Takashi
T
Yatabe
Yasushi
Y
D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology*; D004379:Duodenal Neoplasms / Q000473:pathology*; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D012004:Rectal Neoplasms / Q000473:pathology*