title: Reduced 10-year risk of coronary heart disease in patients who participated in a community-based diabetes prevention program: the DEPLOY pilot study.
abstract: OBJECTIVE
  We evaluated whether participation in a community-based group diabetes prevention program might lead to relative changes in composite 10-year coronary heart disease (CHD) risk for overweight adults with abnormal glucose metabolism.
  
  
  METHODS
  We used the UK Prospective Diabetes Study engine to estimate CHD risk for group-lifestyle and brief counseling (control) groups. Between-group risk changes after 4 and 12 months were compared using ANCOVA.
  
  
  RESULTS
  Baseline 10-year risk was similar between treatment groups (P = 0.667). At 4 and 12 months, the intervention group experienced significant decreases in 10-year risk from baseline (-3.28%, P < 0.001; and -2.23%, P = 0.037) compared with control subjects (-0.78%, P = 0.339; and +1.88%, P = 0.073). Between-group differences were statistically significant and increased from the 4- to 12-month visits.
  
  
  CONCLUSIONS
  Community-based delivery of the Diabetes Prevention Program lifestyle intervention could be a promising strategy to prevent both CHD and type 2 diabetes in adults with pre-diabetes.
authors.affiliation: Roudebush Veterans Affairs Medical Center, Health Services Research & Development Center of Excellence for Implementing Evidence-Based Practice, Indianapolis, Indiana, USA. elaine.lipscomb@va.gov
authors.forename: Elaine R
authors.initials: ER
authors.lastname: Lipscomb
authors.forename: Emily A
authors.initials: EA
authors.lastname: Finch
authors.forename: Edward
authors.initials: E
authors.lastname: Brizendine
authors.forename: Chandan K
authors.initials: CK
authors.lastname: Saha
authors.forename: Laura M
authors.initials: LM
authors.lastname: Hays
authors.forename: Ronald T
authors.initials: RT
authors.lastname: Ackermann
mesh_terms: D016022:Case-Control Studies; D003327:Coronary Disease / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D050177:Overweight / Q000150:complications; D010865:Pilot Projects; D013997:Time Factors