Absorption enhancement and conformational control of peptides by small silver clusters.
We explored experimentally and theoretically the optical properties of isolated silver trimer-dipeptide bioconjugates. The metallic moiety induces a strong enhancement of the optical absorption of the peptide. We also show that its binding to a peptide can reduce the conformational flexibility and induce transitions between secondary structures.
Tabarin
Thibault
T
Université de Lyon, F-69622, Lyon, France.
Kulesza
Alexander
A
Antoine
Rodolphe
R
Mitrić
Roland
R
Broyer
Michel
M
Dugourd
Philippe
P
Bonacić-Koutecký
Vlasta
V
D000327:Adsorption; D004151:Dipeptides / Q000737:chemistry*; D008667:Metalloproteins / Q000737:chemistry*; D008958:Models, Molecular; D017433:Protein Structure, Secondary; D018030:Silver Compounds / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods
D004151:Dipeptides; D008667:Metalloproteins; D018030:Silver Compounds; C016810:tryptophylglycine