[Osmotic demyelination syndrome in Addison crisis and severe hyponatremia].
Acute adrenal insufficiency is a life threatening disease with dehydration, hypotension, cerebral dysfunction and gastrointestinal symptoms accompanied by low plasma sodium and high plasma potassium. Osmotic demyelination syndrome (ODS) can occur rarely following correction of plasma sodium. We describe a case with extremely low plasma sodium and subsequent development of ODS. Correction which is too slow may lead to cerebral oedema, brain stem herniation and low sodium encephalopathy. Correction which is too fast may cause ODS. The dilemma is accentuated by concomitant Addison crisis.
Andersen
Signe Elisabeth Bødker
SE
Skovvangsvej 60, 3. th., DK-8200 Arhus N. seba@studmed.au.dk
Stausbøl-Grøn
Brian
B
Rasmussen
Torsten Bloch
TB
D000224:Addison Disease / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D001921:Brain / Q000473:pathology; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D007010:Hyponatremia / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male