title: Mouth floor enlargements related to the sublingual glands in edentulous or partially edentulous patients: a microscopic study.
abstract: Mouth floor enlargements (MFE) are observed in edentulous and partially edentulous patients, impairing denture fitting, and have recently been described in the literature as hyperplasias of the sublingual glands.
  
  
  OBJECTIVE
  This study aims at describing the microscopic aspects of MFE that contribute to their final diagnosis.
  
  
  METHODS
  Twenty-four specimens were surgically removed from the enlarged mouth floor of 19 patients (15 females and 4 males). Patient age ranged from 48 to 74 years, with a mean of 57 years. The main surgical indication was to permit or improve the fitting of dentures. Six patients were completely edentulous and 13 were partially edentulous. The material was processed for microscopic examination and stained with hematoxylin-eosin, Mallory's trichrome and periodic-acid Schiff (PAS).
  
  
  CONCLUSIONS
  The epithelium of the mouth floor was normal in 17 cases, hyperplastic in 4 and atrophic in 3. Six of the 24 sublingual glands removed were microscopically normal, while the other specimens presented acinar atrophy with hyperplasia of duct-like structures. Interstitial fibrosis was observed in 18 cases and was accompanied by adipose tissue infiltration in 15. Decreased lymphoid tissue was observed in 16 samples and oncocytosis was present in 5 cases. We suggest that MFE in edentulous or partially edentulous patients should be considered as an entity for the text books.
authors.affiliation: State University of Maringá - Paraná - Brazil.
authors.forename: Liogi
authors.initials: L
authors.lastname: Iwaki Filho
authors.forename: José Humberto
authors.initials: JH
authors.lastname: Damante
authors.forename: Alberto
authors.initials: A
authors.lastname: Consolaro
authors.forename: Wellington Cardoso
authors.initials: WC
authors.lastname: Bonachela
authors.forename: Carla Andreotti
authors.initials: CA
authors.lastname: Damante