HBOC-201: the multi-purpose oxygen therapeutic.
Clinical and preclinical studies have revealed a diverse array of indications in which the effectiveness of HBOC-201 has been demonstrated or appears likely. Included among these are indications involving cardiac and peripheral ischaemia in which this oxygen therapeutic may prove to be an important tool in the armamentarium of the cardiologist and surgeon. Preclinical studies and clinical trials are under way to further delineate and optimise the role of HBOC-201 as an oxygen therapeutic in cardiovascular medicine.
Dubé
Gregory P
GP
Cardiovascular Research, Biopure Corporation, Cambridge, Massachusetts 02141, USA. gdube@biopure.com
Vranckx
Pascal
P
Greenburg
A Gerson
AG
D000740:Anemia / Q000628:therapy*; D000818:Animals; D016063:Blood Loss, Surgical; D001802:Blood Substitutes / Q000627:therapeutic use*; D006454:Hemoglobins / Q000627:therapeutic use*; D006801:Humans; D016032:Randomized Controlled Trials as Topic
D001802:Blood Substitutes; D006454:Hemoglobins; C096798:HBOC 201