Association of Cheyne-Stokes respiration and cardiac cachexia in congestive heart failure.
In patients with congestive heart failure (CHF) cachexia as well as Cheyne-Stokes respiration (CSR) are well known disorders. The relationship between CSR and cardiac cachexia however, remains unclear so far. Clinical as well as full-night polysomnographic data from 12 cachectic patients were compared to 13 non-cachectic patients with CHF. The non-cachectic patients did not differ significantly in age (57.3+/-11.6 vs 64.8+/-14.5 years), body mass index (26.4+/-4.0 vs 25.2+/-3.2 kg m-(2)) or ejection fraction (21.8+/-5 vs 23.3+/-7%) from cachectic patients. The weight loss was 2.1+/-2.3 kg in non-cachectic vs 11.5+/-2.7 kg in cachectic patients (p<0.0001). A significant difference was detected for the prevalence CSR (5 vs 10 patients, p<0.03). In this study a high prevalence of sleep breathing disorders, in particular of CSR in CHF patients with cachexia was detected.
Hagenah
Gerrit C
GC
Luers
Claus
C
Prager
Denise
D
Blaschke
Sabine
S
D000368:Aged; D002100:Cachexia / Q000453:epidemiology*; D002639:Cheyne-Stokes Respiration / Q000453:epidemiology*; D006333:Heart Failure / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D012891:Sleep Apnea Syndromes / Q000453:epidemiology*