title: Catalytic carbon-carbon sigma bond activation: an intramolecular carbo-acylation reaction with acylquinolines.
abstract: Carbon-carbon sigma-bond activation is a contemporary challenge for organometallic chemistry and catalysis. Herein, we disclose a new alkene carboacylation reaction initiated by quinoline-directed, rhodium-catalyzed C-C sigma bond activation. The alkene carboacylation allows for the construction of all-carbon quaternary centers, with a broad substrate scope, providing access to carbocyclic and heterocyclic ring systems in good to excellent yields.
authors.affiliation: Department of Chemistry, University of Minnesota-Twin Cities, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, USA.
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Dreis
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Douglas