title: Disseminated Leishmania infantum infection in two sibling foxhounds due to possible vertical transmission.
abstract: Two sibling foxhounds born to a Leishmania seropositive bitch were presented after testing seropositive for Leishmania. Leishmania infantum infection was detected via histopathology, culture, and quantitative polymerase chain reaction (q-PCR). This is the first report of natural infection with Leishmania infantum with the possibility for vertical transmission in North America.
authors.affiliation: Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011-1250, USA. kngibson@iastate.edu
authors.forename: Katherine N
authors.initials: KN
authors.lastname: Gibson-Corley
authors.forename: Jesse M
authors.initials: JM
authors.lastname: Hostetter
authors.forename: Shannon J
authors.initials: SJ
authors.lastname: Hostetter
authors.forename: Kathleen
authors.initials: K
authors.lastname: Mullin
authors.forename: Amanda E
authors.initials: AE
authors.lastname: Ramer-Tait
authors.forename: Paola M
authors.initials: PM
authors.lastname: Boggiatto
authors.forename: Christine A
authors.initials: CA
authors.lastname: Petersen
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000635:transmission*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary*; D018314:Leishmania infantum / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000635:transmission / Q000662:veterinary*; D008297:Male; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis / Q000662:veterinary*