Isolation, in vitro cultivation and characterisation of foetal liver cells.
Hepatocyte transplantation has recently become an efficient clinical method in the treatment of patients with metabolic liver diseases. The shortage of donor cells remains an obstacle to treat more patients. Foetal liver tissues may therefore be useful as an alternative source of generating functional hepatocytes after in vitro culture and maturation.
Wu
Yue
Y
Stem Cell Biology Laboratory, Wolfson Centre for Age-Related Diseases King's College London, London, UK.
Shatapathy
Chetan C
CC
Minger
Stephen L
SL
D000818:Animals; D018929:Cell Culture Techniques / Q000379:methods; D002469:Cell Separation / Q000379:methods; D004622:Embryo, Mammalian / Q000166:cytology; D005333:Fetus / Q000166:cytology*; D022781:Hepatocytes / Q000166:cytology / Q000637:transplantation; D006801:Humans; D008099:Liver / Q000166:cytology*; D051381:Rats; D011916:Rats, Inbred F344; D020858:Tissue and Organ Harvesting / Q000379:methods*