title: Gastrointestinal tract pseudo-obstruction or obstruction due to Mycobacterium tuberculosis breakthrough.
abstract: The development of tuberculosis-related bowel obstruction or pseudo-obstruction during anti-tuberculosis therapy is rarely reported in immunocompetent patients. A 44-year-old male, who had neither HIV infection nor diabetes, was hospitalized because of pulmonary tuberculosis in November 2006. Three months after starting anti-tuberculosis therapy, he was admitted for suspected mechanical bowel obstruction. An emergency exploratory laparotomy showed distended bowel loops, and multiple skip lesions from the terminal ileum to the ascending colon. PCR analyses showed Mycobacterium tuberculosis. The therapy regimen was unchanged after the operation; the patient gradually improved over the course of a month and was discharged without further symptoms thereafter.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chien-Wei
authors.initials: CW
authors.lastname: Lee
authors.forename: Wen-Hsiung
authors.initials: WH
authors.lastname: Chang
authors.forename: Shou-Chuan
authors.initials: SC
authors.lastname: Shih
authors.forename: Tsang-En
authors.initials: TE
authors.lastname: Wang
authors.forename: Chen-Wang
authors.initials: CW
authors.lastname: Chang
authors.forename: Ming-Jong
authors.initials: MJ
authors.lastname: Bair
authors.forename: Ruey-An
authors.initials: RA
authors.lastname: Chiang
authors.forename: Yu-Jan
authors.initials: YJ
authors.lastname: Chen
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003106:Colon / Q000382:microbiology; D006801:Humans; D007082:Ileum / Q000382:microbiology; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D007418:Intestinal Pseudo-Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D013183:Sputum / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents