title: Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases.
abstract: Papillary glioneuronal tumors are a newly recognized type of brain neoplasm characterized by prominent pseudopapillary structures and glioneuronal elements. All prior cases have shown that these tumors have an indolent course. The authors present 2 patients with an aggressive variant of the tumor. The first patient had dissemination of her tumor and the second had local spreading. Therefore, the authors conclude that papillary glioneuronal tumors do not always behave in a strictly benign fashion.
authors.affiliation: Division of Neurosurgery, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
authors.forename: Ramin J
authors.initials: RJ
authors.lastname: Javahery
authors.forename: Laurence
authors.initials: L
authors.lastname: Davidson
authors.forename: Jason
authors.initials: J
authors.lastname: Fangusaro
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Finlay
authors.forename: Ignacio
authors.initials: I
authors.lastname: Gonzalez-Gomez
authors.forename: J Gordon
authors.initials: JG
authors.lastname: McComb
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D002540:Cerebral Cortex / Q000473:pathology / Q000601:surgery*; D002648:Child; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000473:pathology / Q000601:surgery*; D018303:Ganglioglioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D018193:Neoplasms, Complex and Mixed / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012086:Reoperation; D014746:Vimentin / Q000032:analysis
chemical_list: D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin