title: Psychotic disorder and extrapyramidal symptoms associated with vitamin B12 and folate deficiency.
abstract: Vitamin B12 and folate deficiency causing neuropsychiatric and thrombotic manifestations, such as peripheral neuropathy, subacute combined degeneration of cord, dementia, ataxia, optic atrophy, catatonia, psychosis, mood disturbances, myocardial infarction and portal vein thrombosis are well known. This present report highlights an unusual presentation of vitamin B12 deficiency-psychotic disorder, extrapyramidal symptoms in a 12-year-old boy. His symptoms responded to parenteral vitamin B12 therapy. So with this report we emphasized that serum vitamin B12 and folate levels should be measured, especially in those patients who present with other known neuropsychiatric features of vitamin B12 and folate deficiency.
authors.affiliation: Department of Pediatric Endocrinology, YYU. doganmurat.md@gmail.com
authors.forename: Murat
authors.initials: M
authors.lastname: Dogan
authors.forename: Osman
authors.initials: O
authors.lastname: Ozdemir
authors.forename: Ertan A
authors.initials: EA
authors.lastname: Sal
authors.forename: S Zehra
authors.initials: SZ
authors.lastname: Dogan
authors.forename: Pinar
authors.initials: P
authors.lastname: Ozdemir
authors.forename: Yasar
authors.initials: Y
authors.lastname: Cesur
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Caksen
mesh_terms: D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000209:etiology*; D002648:Child; D005492:Folic Acid / Q000097:blood; D005494:Folic Acid Deficiency / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D014805:Vitamin B 12 / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000097:blood / Q000150:complications* / Q000175:diagnosis
chemical_list: D005492:Folic Acid; D014805:Vitamin B 12