title: Trajectory analysis for magnetic particle imaging.
abstract: Recently a new imaging technique called magnetic particle imaging was proposed. The method uses the nonlinear response of magnetic nanoparticles when a time varying magnetic field is applied. Spatial encoding is achieved by moving a field-free point through an object of interest while the field strength in the vicinity of the point is high. A resolution in the submillimeter range is provided even for fast data acquisition sequences. In this paper, a simulation study is performed on different trajectories moving the field-free point through the field of view. The purpose is to provide mandatory information for the design of a magnetic particle imaging scanner. Trajectories are compared with respect to density, speed and image quality when applied in data acquisition. Since simulation of the involved physics is a time demanding task, moreover, an efficient implementation is presented utilizing caching techniques.
authors.affiliation: Institute of Medical Engineering, University of Lübeck, Lübeck, Germany. knopp@imt.uni-luebeck.de
authors.forename: T
authors.initials: T
authors.lastname: Knopp
authors.forename: S
authors.initials: S
authors.lastname: Biederer
authors.forename: T
authors.initials: T
authors.lastname: Sattel
authors.forename: J
authors.initials: J
authors.lastname: Weizenecker
authors.forename: B
authors.initials: B
authors.lastname: Gleich
authors.forename: J
authors.initials: J
authors.lastname: Borgert
authors.forename: T M
authors.initials: TM
authors.lastname: Buzug
mesh_terms: D000465:Algorithms; D001698:Biomedical Engineering; D055592:Biophysical Phenomena; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008280:Magnetics; D053768:Metal Nanoparticles; D008962:Models, Theoretical; D036103:Nanotechnology; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D014054:Tomography / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data