title: Calibrated magnetic resonance hydrometry to quantify pancreatic juice: a preliminary study.
abstract: OBJECTIVE
  To investigate the effectiveness of the calibrated MR hydrometry (CMRH) method for accurately measuring pancreatic secretion.
  
  
  METHODS
  All studies were performed on a 1.5-T MR system using a fat-suppressed, single-shot half-Fourier fast spin-echo sequence with a standard body coil. A certain volume (20 mL) of saline solution was employed as an extrabody calibrator. The validity of the CMRH method was tested both in vitro and in vivo, and actual and calculated volumes were compared.
  
  
  RESULTS
  The in vitro study yielded a high correlation (r = 0.99; P < 0.0001) between the actual volume of saline solution in the imaging field and the calculated volume. In the in vivo study, for all volunteers, there was a very strong and significant positive correlation between the measured signal intensities or calculated volumes and actual volumes (correlation coefficient range: 0.94-0.99; P < 0.0001).
  
  
  CONCLUSIONS
  This preliminary study shows that CMRH is an effective tool to measure the amount of pancreatic fluid secretion.
authors.affiliation: Department of Radiology, YanBian University, YanJi, China.
authors.forename: En-Hao
authors.initials: EH
authors.lastname: Jin
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Ichikawa
authors.forename: Sukru Mehmet
authors.initials: SM
authors.lastname: Erturk
authors.forename: Utaroh
authors.initials: U
authors.lastname: Motosugi
authors.forename: Masaya
authors.initials: M
authors.lastname: Hirano
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Araki
mesh_terms: D000328:Adult; D002138:Calibration; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods* / Q000592:standards*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards*; D008297:Male; D010189:Pancreatic Juice / Q000737:chemistry*; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014421:Turkey