[Posterior polymorphous dystrophy--changes in corneal morphology in confocal microscopy].
OBJECTIVE
To describe the in vivo conocal microscopic findings in posterior polymorphous dystrophy (PPD).


METHODS
Eleven patients (22 eyes) with PPD suspected or clinically diagnosed were examined using scanning slit white light confocal microscopy (ConfoScan 3, Nidek Technologies).


RESULTS
Endothelial cell densities ranged from 716 to 2380 cells/mm2 and endothelial polymegathism was noted in all cases. In 5 cases PPD changes was reported unilateral. Confocal microscopy demonstrated a variety of vesicular and linear abnormalities. In 13 eyes exhibited bright, nucleus-like structures within endothelial cells. Stromal edema was noted in 4 cases.


CONCLUSIONS
To our knowledge, we present the largest case series of PPD imaged by in vivo confocal microscopy. Confocal microscopy images of PPD are very characteristic. This method allows to confirm presumptive or to identify final diagnosis. Our study enhances the value of confocal microscopy in detection and monitoring corneal abnormalities.
Szaflik
Jacek P
JP
Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Uniwersytetu Medycznego w Warszawie. jacek@amwaw.edu.pl
Kołodziejska
Urszula
U
Udziela
Monika
M
Kołodziejczyk
Wojciech
W
Szaflik
Jerzy
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002452:Cell Count; D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D003319:Corneal Stroma / Q000473:pathology; D019781:Corneal Topography / Q000295:instrumentation* / Q000379:methods; D003886:Descemet Membrane / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal / Q000379:methods; D008875:Middle Aged; D011044:Poland; D012680:Sensitivity and Specificity