title: [A case of esophageal cancer with recurrent lymph-node metastasis successfully treated with chemo-radiotherapy after mediastinoscopy-assisted transhiatal esophagectomy].
abstract: A 63-year-old man who was diagnosed T1b esophageal cancer, for which transthoracic esophagectomy was indicated, received mediastinoscopy-assisted transhiatal esophagectomy because of the previous right thoracotomy for pulmonary tuberculosis. CT study revealed an upper mediastinal lymph-node metastasis 3 years after surgery. He was treated with chemotherapy of daily continuous 5-FU infusion (500 mg/day) and daily nedaplatin (5 mg x 5 days/week) for 4 weeks combined with concurrent radiotherapy (44 Gy). A partial response was achieved for the metastatic lymph-node lesion after chemo-radiotherapy, so boost radiotherapy (16 Gy) was given to the patient. He is still alive now without a re-growth of the lymph-node metastasis. It is important to follow-up the patient with advanced esophageal cancer carefully who received mediastinoscopy-assisted transhiatal esophagectomy.
authors.affiliation: Dept. of Digestive Surgery and Surgical Oncology (Dept. of Surgery II), Yamaguchi University Graduate School of Medicine.
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Yoshino
authors.forename: Shigeru
authors.initials: S
authors.lastname: Takeda
authors.forename: Taku
authors.initials: T
authors.lastname: Nishimura
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Tokunou
authors.forename: Masaaki
authors.initials: M
authors.lastname: Oka
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D016629:Esophagectomy; D004945:Esophagoscopy; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D008481:Mediastinoscopy; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012008:Recurrence; D012074:Remission Induction; D014057:Tomography, X-Ray Computed
chemical_list: D009944:Organoplatinum Compounds; C053989:nedaplatin; D005472:Fluorouracil