Calibrated magnetic resonance hydrometry to quantify pancreatic juice: a preliminary study.
OBJECTIVE
To investigate the effectiveness of the calibrated MR hydrometry (CMRH) method for accurately measuring pancreatic secretion.


METHODS
All studies were performed on a 1.5-T MR system using a fat-suppressed, single-shot half-Fourier fast spin-echo sequence with a standard body coil. A certain volume (20 mL) of saline solution was employed as an extrabody calibrator. The validity of the CMRH method was tested both in vitro and in vivo, and actual and calculated volumes were compared.


RESULTS
The in vitro study yielded a high correlation (r = 0.99; P < 0.0001) between the actual volume of saline solution in the imaging field and the calculated volume. In the in vivo study, for all volunteers, there was a very strong and significant positive correlation between the measured signal intensities or calculated volumes and actual volumes (correlation coefficient range: 0.94-0.99; P < 0.0001).


CONCLUSIONS
This preliminary study shows that CMRH is an effective tool to measure the amount of pancreatic fluid secretion.
Jin
En-Hao
EH
Department of Radiology, YanBian University, YanJi, China.
Ichikawa
Tomoaki
T
Erturk
Sukru Mehmet
SM
Motosugi
Utaroh
U
Hirano
Masaya
M
Araki
Tsutomu
T
D000328:Adult; D002138:Calibration; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods* / Q000592:standards*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards*; D008297:Male; D010189:Pancreatic Juice / Q000737:chemistry*; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014421:Turkey