title: Cutaneous metastasis of gastric adenocarcinoma: an exuberant and unusual clinical presentation.
abstract: There are different types of skin changes associated with internal malignancy. One type is the skin involvement as a result of cutaneous metastasis from an internal tumor. The skin is an uncommon site for distant metastasis; when it is present the most common sources are breast, lung, and colon. Metastasis generally occurs after an internal malignancy had been discovered and signifies disseminated disease with a poor prognosis. We report an exuberant and rare case of cutaneous metastasis from gastric adenocarcinoma as the first sign of this serious visceral cancer.
authors.affiliation: Serviço de Dermatologia, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Rio de janeiro, Brasil. marcus_hx@hotmail.com
authors.forename: Marcus Henrique
authors.initials: MH
authors.lastname: Xavier
authors.forename: Tadeu de Rezende
authors.initials: Tde R
authors.lastname: Vergueiro
authors.forename: Enoi Guedes
authors.initials: EG
authors.lastname: Vilar
authors.forename: Jane Marcy
authors.initials: JM
authors.lastname: Pinto
authors.forename: Maria Cláudia
authors.initials: MC
authors.lastname: Issa
authors.forename: Gabriela Blatt
authors.initials: GB
authors.lastname: Pereira
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Carocha
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002100:Cachexia / Q000209:etiology; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary* / Q000648:ultrastructure; D005047:Etoposide / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000648:ultrastructure; D013125:Spinal Neoplasms / Q000188:drug therapy / Q000556:secondary; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D017211:Treatment Failure
chemical_list: D005047:Etoposide; D002955:Leucovorin; D005472:Fluorouracil