title: A unique case of ovarian psammocarcinoma with mediastinal, pulmonary, subcutaneous, and omental metastases.
abstract: Psammocarcinoma is a rare form of serous ovarian and peritoneal carcinoma, characterized by abundant psammoma bodies, invasiveness, and low-grade cytological features. Many of the cases which have been reported had extraovarian spread and peritoneal seeding at the time of presentation. We present a case of 45-year-old woman with ovarian psammocarcinoma who initially presented with a metastatic subcutaneous nodule, and was found to have pulmonary and mediastinal metastases. We believe this to be the first report of a psammocarcinoma with these metastases. Ovarian and peritoneal psammocarcinomas are quite rare, and because of this, knowledge of their behavior is limited. Although most seem to follow an indolent course similar to that of borderline lesions of the ovary, this case demonstrates that some of these tumors may be clinically aggressive with distant metastases.
authors.affiliation: Department of Surgery, Western Reserve Care System/Northeast Ohio Universities College of Medicine, Youngstown, OH 44505, USA.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Chase
authors.forename: Dorothy A
authors.initials: DA
authors.lastname: Sparks
authors.forename: Melissa
authors.initials: M
authors.lastname: Gener
authors.forename: James
authors.initials: J
authors.lastname: Smith
mesh_terms: D018284:Cystadenocarcinoma, Serous / Q000556:secondary*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000556:secondary*; D008479:Mediastinal Neoplasms / Q000556:secondary*; D008482:Mediastinum / Q000473:pathology; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D010388:Pelvis / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000556:secondary*; D050151:Subcutaneous Fat / Q000473:pathology