title: Population snapshot of Streptococcus pneumoniae serotype 19A isolates before and after introduction of seven-valent pneumococcal Vaccination for French children.
abstract: Serotype 19A Streptococcus pneumoniae strains are now more frequent in French children than before the introduction of a seven-valent conjugate vaccine (PCV7). By applying multilocus sequence typing to 144 serotype 19A isolates collected before and after beginning PCV7 vaccination, we detected clonal expansion of the preexisting penicillin-intermediate sequence type 276.
authors.affiliation: Service de Microbiologie, Hôpital Robert-Debré (APHP), 75019 Paris, France.
authors.forename: Farah
authors.initials: F
authors.lastname: Mahjoub-Messai
authors.forename: Catherine
authors.initials: C
authors.lastname: Doit
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Koeck
authors.forename: Typhaine
authors.initials: T
authors.lastname: Billard
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Evrard
authors.forename: Philippe
authors.initials: P
authors.lastname: Bidet
authors.forename: Christine
authors.initials: C
authors.lastname: Hubans
authors.forename: Josette
authors.initials: J
authors.lastname: Raymond
authors.forename: Corinne
authors.initials: C
authors.lastname: Levy
authors.forename: Robert
authors.initials: R
authors.lastname: Cohen
authors.forename: Edouard
authors.initials: E
authors.lastname: Bingen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D005602:France / Q000453:epidemiology; D005838:Genotype; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D010406:Penicillins / Q000494:pharmacology; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D022242:Pneumococcal Vaccines / Q000276:immunology*; D015995:Prevalence; D017422:Sequence Analysis, DNA; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D010406:Penicillins; D022242:Pneumococcal Vaccines