Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy.
The molecular mechanisms of growth suppression by retinoic acid (RA) were examined. Our results suggest that the cytostatic effects of RA could be mediated by the activation of endogenous CBR3 gene in oral squamous cell carcinomas (OSCCs), and the expression is a potential marker for oral malignancy.
Ohkura-Hada
Shuri
S
Department of Biochemistry, National Defense Medical College, 3-2 Namiki, Tokorozawa-shi.
Kondoh
Nobuo
N
Hada
Akiyuki
A
Arai
Masaaki
M
Yamazaki
Yutaka
Y
Shindoh
Masanobu
M
Kitagawa
Yoshimasa
Y
Takahashi
Masayuki
M
Ando
Toshifumi
T
Sato
Yasunori
Y
Yamamoto
Mikio
M