title: Quality of life and sleep impairment in chronic cocaine dependents.
abstract: OBJECTIVE
  To evaluate quality of life (QL) and sleep quality impairment of cocaine chronic dependents in use of cocaine.
  
  
  METHODS
  40 patients, chronic cocaine dependents were evaluated (37 M; 3 F), with mean age of 28.92 years, along with 40 controls paired for gender and age. The following instruments were used: a) the semi-structured clinical interview; b) the Brazil Economic Classification; c) the Pittsburgh Sleep Quality Index; d) World Heath Organization Quality of Life-BREF (WHOQOL-BREF).
  
  
  RESULTS
  The cocaine dependents showed QL impairment, with deficits in the physical, psychological and social relations domains. Impaired sleep quality was also observed in the cocaine dependents. However, the QL impairment was not directly due to sleep deficit.
  
  
  CONCLUSIONS
  Chronic cocaine dependents showed impairment in QL and sleep impairment. However, for the cocaine dependent group, sleep impairment was not regarded as compromising QL probably because cocaine, rather than sleep, was the main factor negatively influencing QL.
authors.affiliation: Division of Clinical Neurology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo SP, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Lima
authors.forename: Sueli
authors.initials: S
authors.lastname: Rossini
authors.forename: Rubens
authors.initials: R
authors.lastname: Reimão
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002908:Chronic Disease; D019970:Cocaine-Related Disorders / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011788:Quality of Life / Q000523:psychology*; D012893:Sleep Wake Disorders / Q000139:chemically induced / Q000523:psychology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires