title: Use of Coaxil (tianeptine) in elderly patients with combined mild cognitive and depressive-anxiety disorders.
abstract: The studies reported here addressed 20 patients aged 60-69 years whose clinical picture combined the manifestations of mild dementia with those of mild depression and anxiety. Patients were treated with Coaxil (tianeptine) for 60 days at a dose of 37.5 mg/day. Patients were assessed by clinical-psychological investigations with addition of the Hamilton scales and neuropsychological testing by the Luriya method. Coaxil was found to be highly effective in relation to all psychopathological components. Recommendations for the use of Coaxil in elderly patients with cognitive and depressive-anxiety disorders are formulated.
authors.affiliation: Nizhnii Novgorod State Medical Academy, Nizhnii Novgorod, Russia.
authors.forename: I B
authors.initials: IB
authors.lastname: Karpukhin
mesh_terms: D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000453:epidemiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D013841:Thiazepines / Q000627:therapeutic use*
chemical_list: D000929:Antidepressive Agents, Tricyclic; D013841:Thiazepines; C050504:tianeptine