[Primary peripheral T-cell lymphoma of the penis: a case report and review of the literature].
OBJECTIVE
To report a case of primary peripheral T-cell lymphoma of the penis.


METHODS
We analyzed the clinicopathological characteristics of the case of primary peripheral T-cell lymphoma using histological, cytochemical and immunohistochemical methods and by review of the literature.


RESULTS
The patient was a 65 years old man and presented with a diffuse enlargement of the penis as the initial sign, followed by erosive ulcer in the caput penis and inguinal lymphadenectasis. The tumor was pathohistologically manifested as an epidermal ulcer, with tumorous necrosis around the capillary, infiltrative growth and atypical changes of the neoplastic cells and proliferation of capillaries. Immunohistochemically, the tumor cells were positive for CD43 and CD3, but negative for CD20, CD79a, CD34, CD30, CD56 and CD34. Clinically it responded to the chemotherapy designed for peripheral T-cell lymphoma.


CONCLUSIONS
Primary peripheral T-cell lymphoma of the penis is an extremely rare malignant tumor, the diagnosis of which relies on histopathological examination, immunohistochemical staining and differentiation between squamous cell carcinoma and other types of lymphoma.
Shi
Yan-Lin
YL
Department of Pathology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.
Yin
Hong-Lin
HL
Zhou
Xiao-Jun
XJ
Zhou
Hang-Bo
HB
Lu
Zhen-Feng
ZF
D000368:Aged; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral; D008297:Male; D010412:Penile Neoplasms; D013601:T-Lymphocytes