Cancer mortality among men in Central Serbia: 1985-2006 survey study.
OBJECTIVE
To analyze cancer mortality trends in men in Central Serbia during 1985-2006 period.


METHODS
Mortality rates and trends for the most frequent cancers in men (lung, stomach, colorectal, pancreatic, and prostate cancer) were calculated. Mortality rates for all cancers were adjusted by direct standardization. Percentage changes of the rates were calculated as the percentage difference between the rates of two successive years and then as a mean of these changes for the entire observed period. Trend lines were estimated using linear regression.


RESULTS
Total cancer mortality in men increased, with mean percentage of annual changes being 1.53% (95% confidence interval [CI], -0.09-3.16). Lung, stomach, colorectal, pancreatic, and prostate cancers represented 58.1% and 61.6% of total cancer deaths in 1985 and 2006, respectively. Increasing trends were observed for all investigated cancers: mean annual percentage change for lung cancer was 2.31%(95% CI, 1.03-3.59), for colorectal cancer 2.23% (95% CI, -0.18-4.65), for prostate cancer 3.06% (95% CI, -2.07-8.18), and for pancreatic cancer 1.58% (95% CI, -2.17-5.32). Stomach cancer mortality significantly decreased in age groups 40-49 and 50-59 years.


CONCLUSIONS
The most frequent cancers in men in Central Serbia, i.e., lung, colorectal, prostate, and pancreatic cancer, showed an increasing trend. Only stomach cancer mortality decreased over time.
Marković-Denić
Ljiljana
L
Institute of Epidemiology, School of Medicine, Belgrade University, Visegradska 26, Belgrade, Serbia. lj.denic@gmail.com
Vlajinac
Hristina
H
Zivković
Snezana
S
Miljus
Dragan
D
D000328:Adult; D000368:Aged; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D009369:Neoplasms / Q000401:mortality*; D055771:Serbia / Q000453:epidemiology