title: [Measuring blood flow change of osteonecrosis of femoral head with laser doppler flowmetry].
abstract: OBJECTIVE
  To detect the blood perfusion of the necrotic area and the femoral head and neck junction in the patients diagnosed as osteonecrosis of femoral head (ONFH) with laser doppler flowmetry (LDF).
  
  
  METHODS
  From 2007 to 2008, 50 patients with ONFH 82 hips were performed core decompression and autologous stem cells transplantation. Group A was for ARCO stage II 46 hips (IIA 6 hips, IIB 22 hips, IIC 18 hips), and Group B was for stage III 36 hips (IIIA 20 hips, IIIB 10 hips, IIIC 6 hips). Blood perfusion of necrotic area and femoral head and neck junction with LDP were detected during the operation. Statistical analysis was made.
  
  
  RESULTS
  In Group A, the perfusion volume of necrotic area was (30.2 +/- 3.0) PU, and the perfusion volume of femoral head and neck junction was (103.4 +/- 4.4) PU. In Group B, the perfusion volume of necrotic area was (30.6 +/- 2.8) PU, and the perfusion volume of femoral head and neck junction was (103.4 +/- 3.9) PU. In Group A and Group B, the perfusion volume of necrotic area was lower than that of femoral head and neck junction, and the difference was significant (P < 0.01).
  
  
  CONCLUSIONS
  LDF can effectively detect that the perfusion volume of ONFH decreased, which provides a theoretical basis in order to further study the pathogenesis of ONFH. Meanwhile, there is application value of LDF on the study of ONFH.
authors.affiliation: Graduate School, Peking Union Medical College, Beijing 100730, China. LZR96@hotmail.com
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Min
authors.forename: Zi-rong
authors.initials: ZR
authors.lastname: Li
authors.forename: Li-ming
authors.initials: LM
authors.lastname: Cheng
authors.forename: Zhen-cai
authors.initials: ZC
authors.lastname: Shi
mesh_terms: D000328:Adult; D005260:Female; D005270:Femur Head / Q000098:blood supply*; D005271:Femur Head Necrosis / Q000473:pathology*; D006439:Hemodynamics; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D008875:Middle Aged