Anxiolytic and antidepressant characteristics of impaza.
Antibodies to endothelial NO synthase in ultralow doses exhibited anxiolytic and antidepressant effects and their efficiency after single and course treatment is not inferior to that of amitriptyline and diazepam. The psychotropic activity of ultralow-dose antibodies to endothelial NO-synthase is presumably one of important mechanisms of their efficiency in the treatment of erectile dysfunction.
Voronina
T A
TA
Materia Medica Holdings, Moscow.
Molodavkin
G M
GM
Zhavbert
E S
ES
Tarasov
S A
SA
Kheyfets
I A
IA
Dugina
J L
JL
Sergeeva
S A
SA
Epstein
O I
OI
D000639:Amitriptyline / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000906:Antibodies / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003863:Depression / Q000517:prevention & control / Q000523:psychology; D003975:Diazepam / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D018782:Maze Learning / Q000187:drug effects; D052250:Nitric Oxide Synthase Type III / Q000276:immunology; D051381:Rats; D013315:Stress, Psychological / Q000517:prevention & control / Q000523:psychology; D013550:Swimming / Q000523:psychology
D014151:Anti-Anxiety Agents; D000906:Antibodies; D000928:Antidepressive Agents; D000639:Amitriptyline; D052250:Nitric Oxide Synthase Type III; D003975:Diazepam