title: Mycobacterium tuberculosis infection within parotid gland Warthin tumor.
abstract: Tuberculosis of the parotid gland is extremely unusual. Tuberculosis comprises 2.5% to 10% of parotid gland lesions. Two clinical forms of parotid gland tuberculosis infection exist. One is a diffuse parenchymatous disease (either primary or secondary to nodal disease), resembling common infection. The second is a chronic, slow-growing, painless, and firm parotid mass mimicking a neoplasm. Most of these patients were diagnosed after parotid gland surgery and histopathologic evaluation. Warthin tumor is a well-known benign neoplasm of the salivary glands. It is the second most common tumor of the parotid gland. Mycobacterium tuberculosis within Warthin tumor is also unusual. Five cases with parotid gland tuberculosis within Warthin tumor were reported in the literature. In this report, we present a new patient with parotid gland tuberculosis within the Warthin tumor. This type parotid gland pathology is an extremely rare entity, and to the best of our knowledge, this is the second documented case using polymerase chain reaction. We also discussed the possible mechanisms of development of infection within Warthin tumor.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, Mersin University, Mersin, Turkey. cozcan@mersin.edu.tr
authors.forename: Cengiz
authors.initials: C
authors.lastname: Ozcan
authors.forename: Duygu Düşmez
authors.initials: DD
authors.lastname: Apa
authors.forename: Gönül
authors.initials: G
authors.lastname: Aslan
authors.forename: Stk
authors.initials: S
authors.lastname: Gülhan
authors.forename: Kemal
authors.initials: K
authors.lastname: Görür
mesh_terms: D000235:Adenolymphoma / Q000175:diagnosis*; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D003287:Contrast Media; D004269:DNA, Bacterial / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics; D010305:Parotid Diseases / Q000175:diagnosis*; D010307:Parotid Neoplasms / Q000175:diagnosis*; D016133:Polymerase Chain Reaction; D014375:Tuberculoma / Q000175:diagnosis; D014393:Tuberculosis, Oral / Q000175:diagnosis*
chemical_list: D000995:Antitubercular Agents; D003287:Contrast Media; D004269:DNA, Bacterial