Generalized eruptive keratoacanthomas of Grzybowski treated with isotretinoin.
Generalized eruptive keratoacanthomas of Grzybowski is a rare condition of unknown etiology. The disease is characterized by the abrupt onset of many small crateriform papules on the skin and mucous membranes. The authors report of a man with multiple eruptive keratoacanthomas of Grzybowski who responded favorably to oral isotretinoin therapy. After 2 years of follow-up, a complete regression of all lesions was observed, and this rapid clearance under isotretinoin therapy is intriguing with regard to the possible etiology of the condition.
Vandergriff
Travis
T
Presbyterian- St. Luke's Hospital, Denver, CO, USA.
Nakamura
Krystal
K
High
Whitney A
WA
D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use*; D015603:Keratinocytes / Q000187:drug effects / Q000473:pathology; D007636:Keratoacanthoma / Q000188:drug therapy* / Q000473:pathology*; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology
D007641:Keratolytic Agents; D015474:Isotretinoin