title: Effect of spherical aberration on visual function under photopic and mesopic conditions after cataract surgery.
abstract: OBJECTIVE
  To evaluate the effect of spherical aberration on visual function under natural pupil conditions after cataract surgery.
  
  
  METHODS
  Keio University Hospital, Tokyo, Japan.
  
  
  METHODS
  This study comprised cataract patients who had cataract extraction with implantation of an acrylic intraocular lens. Preoperative and postoperative visual acuity, higher-order aberration in the whole eye, contrast sensitivity function, and pupil diameter under photopic and mesopic conditions 1 month after surgery were measured. The area under log contrast sensitivity function (AULCSF) and spherical aberration corresponding to the individual pupil diameter under photopic and mesopic conditions were evaluated.
  
  
  RESULTS
  One hundred seven eyes of 79 patients (30 men, 49 women; mean age 68.0 years +/- 9.6 [SD]) were evaluated. The mean pupil diameter was 2.9 +/- 0.50 mm under photopic conditions and 3.6 +/- 0.57 mm under mesopic conditions. The mean spherical aberration was 0.03 +/- 0.04 mum (range -0.12 to 0.34 mum) under photopic conditions and 0.05 +/- 0.10 mum (range -0.14 to 0.55 mum) under mesopic conditions. The postoperative AULCSF without glare under photopic conditions was significantly negatively correlated with spherical aberration (P = .014). The postoperative AULCSF with and without glare under mesopic conditions was significantly negatively correlated with spherical aberration (P<.001 and P = .01, respectively).
  
  
  CONCLUSIONS
  Postoperative spherical aberration had a significant effect on visual function under photopic and mesopic conditions. This result indicates that reduced postoperative spherical aberration improves postoperative visual function under photopic and mesopic conditions.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Takefumi
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Murat
authors.initials: M
authors.lastname: Dogru
authors.forename: Kazuko
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ono
authors.forename: Megumi
authors.initials: M
authors.lastname: Saiki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Okuyama
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
authors.forename: Kazuno
authors.initials: K
authors.lastname: Negishi
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D015350:Contrast Sensitivity / Q000502:physiology; D005260:Female; D019466:Glare; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008027:Light; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D019591:Pseudophakia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology* / Q000528:radiation effects; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D000180:Acrylic Resins