POEMS syndrome: a case report.
A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation. The clinical evaluation met the criteria for the diagnosis of POEMS syndrome. The patient was initially treated with prednisolone and responded well. We planned high-dose chemotherapy with autologous stem cell rescue and introduced a more immunosuppressive regimen containing cyclophosphamide and dexamethasone. We present a case differing from the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.
Ozden
Ali
A
Departments of Gastroenterology School of Medicine, Ankara University, Ankara. drokocaman@hotmail.com.
Süleyman
Zeygam
Z
Seven
Gülseren
G
Arat
Mutlu
M
Akin
Alper
A
Sener
Ozden
O
Kuzu
Işinsu
I
Keven
Kenan
K
Ensari
Arzu
A
Erden
Ayşe
A
Tan
Ersin
E
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016878:POEMS Syndrome / Q000175:diagnosis* / Q000188:drug therapy
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003907:Dexamethasone; D003520:Cyclophosphamide