Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides.
Efficient enzymatic syntheses of isosteric phosphono analogues of sugar nucleotides have been accomplished using a thymidylyltransferase.
Beaton
Stephen A
SA
Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J3.
Huestis
Malcolm P
MP
Sadeghi-Khomami
Ali
A
Thomas
Neil R
NR
Jakeman
David L
DL
D055162:Biocatalysis; D002240:Carbohydrate Sequence; D007700:Kinetics; D009711:Nucleotides / Q000096:biosynthesis* / Q000737:chemistry; D009713:Nucleotidyltransferases / Q000378:metabolism*; D013403:Sugar Phosphates / Q000096:biosynthesis* / Q000737:chemistry
D009711:Nucleotides; D013403:Sugar Phosphates; D009713:Nucleotidyltransferases; C020587:glucose-1-phosphate thymidylyltransferase