title: [Antimicrobial resistance after antibiotic use in animals--impact on human health].
abstract: BACKGROUND
  This review describes the use of antibiotics and the occurrence of antimicrobial resistance in animal husbandry, with emphasis on the current situation in Norway. The clinically most important resistance problems in human medicine that are associated with antimicrobial resistance in animals, are discussed in a global perspective.
  
  
  METHODS
  This review is based on a Pubmed search with the terms "animal" and "antimicrobial resistance", as well as the authors' own research experience.
  
  
  RESULTS
  Antibiotic use in animals is the main cause for selection and dissemination of antimicrobial resistance in animals. The prevalence of antimicrobial resistance in animal husbandry in Norway is lower than that in many non-Nordic countries, and is associated with less use of therapeutic antibiotics. Antimicrobial resistance may spread from animals to humans by transfer of resistant bacteria from animals to humans and resistance genes from animal bacteria to human pathogens.
  
  
  CONCLUSIONS
  It is adamant to have efficient prevention measures and rational use of antibiotics in animals to delay development of antibiotic resistant bacteria. Although good examples exist of how resistance in animal bacteria can create problems for human health, it is well documented that the human use of therapeutic antibiotics and lack of efficient infection control measures have the most profound influence on the occurrence of antibiotic resistance in humans.
authors.affiliation: Avdeling for mikrobiologi og virologi Institutt for medisinsk biologi Det medisinske fakultet Universitetet i Tromsø 9037 Tromsø. arnfinn.sundsfjord@fagmed.uit.no
authors.forename: Arnfinn
authors.initials: A
authors.lastname: Sundsfjord
authors.forename: Marianne
authors.initials: M
authors.lastname: Sunde
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D001424:Bacterial Infections / Q000188:drug therapy / Q000635:transmission / Q000662:veterinary; D004197:Disease Reservoirs; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004363:Drug Utilization; D005516:Food Microbiology; D006801:Humans; D014730:Veterinary Medicine; D014871:Water Microbiology
chemical_list: D000900:Anti-Bacterial Agents