PCOS, sexuality, and clitoral vascularisation: a pilot study.
BACKGROUND
In polycystic ovarian syndrome (PCOS) women, the changes in body appearance (mainly obesity and hirsutism) may influence the feminine identity of the patients with consequent depression and sexual disturbances.


OBJECTIVE
To evaluate if lean PCOS patients present an increased incidence of depression and sexual dysfunction in comparison with controls and if clitoral volume and vascularization are influenced by circulating androgens levels.


METHODS
25 lean PCOS women (Group I) and 18 healthy nonhirsute volunteers (Group II) were submitted, on day 3-5 of the cycle, to ultrasonographic and Doppler analyses, and to hormonal and biochemical evaluations.


METHODS
Utero-ovarian and clitoral ultrasonographic analysis, and color Doppler evaluation of the uterine, stromal ovarian, and dorsal clitoral arteries. Hormonal and nitrites/nitrates plasma concentrations were analyzed. Each woman filled in the 2-factor Italian McCoy female questionnaire (MFSQ) and the Beck's Depression Inventory questionnaire (BDI).


RESULTS
Androgens resulted, as expected, more elevated in PCOS patients than in controls. However, the ultrasonographic (US) assessment of the clitoral body volume evidenced no significant differences between PCOS (0.72+/-0.41 mL) and control (0.62+/-0.20 mL) patients. The resistances registered at the level of the dorsal clitoral artery did not show any difference between Group I (PI=1.55+/-0.40) and Group II (PI=1.79+/-0.38). The 2-factor Italian MFSQ and the BDI did not show any difference between PCOS women and controls.


CONCLUSIONS
In PCOS women, probably, the moderate hirsutism and hyperandrogenism do not induce the sense of loss of feminine identity and have no impact on sexual self-worth and sexual satisfaction.
Battaglia
Cesare
C
Department of Obstetrics and Gynecology, University of Bologna, Bologna, Italy. cesare.battaglia@unibo.it
Nappi
Rossella E
RE
Mancini
Fulvia
F
Cianciosi
Arianna
A
Persico
Nicola
N
Busacchi
Paolo
P
Facchinetti
Fabio
F
Sisti
Giovanni
G
D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood; D001158:Arteries / Q000000981:diagnostic imaging; D001783:Blood Flow Velocity / Q000502:physiology; D002987:Clitoris / Q000098:blood supply* / Q000000981:diagnostic imaging; D003866:Depressive Disorder / Q000503:physiopathology / Q000523:psychology; D005260:Female; D005783:Gender Identity; D012739:Gonadal Steroid Hormones / Q000097:blood; D006628:Hirsutism / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D010053:Ovary / Q000098:blood supply / Q000000981:diagnostic imaging; D010865:Pilot Projects; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000523:psychology; D012725:Sexual Behavior / Q000502:physiology*; D018615:Ultrasonography, Doppler, Color; D014599:Uterus / Q000098:blood supply / Q000000981:diagnostic imaging; D055815:Young Adult
D000728:Androgens; D012739:Gonadal Steroid Hormones