Therapeutic peptide vaccines for treatment of autoimmune diseases.
Recent advances in immunology have led to exciting new possibilities in medicine. We now understand how to design vaccine capable of resetting the balance between immune effector and regulatory cells in people suffering from autoimmune and allergic diseases. These approaches are effective while avoiding the side effects associated with non-specific immune suppression.
Wraith
David C
DC
Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK. d.c.wraith@bristol.ac.uk
D000485:Allergens / Q000276:immunology; D000707:Anaphylaxis / Q000517:prevention & control; D000818:Animals; D017951:Antigen Presentation; D001324:Autoantigens / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D016207:Cytokines / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D003888:Desensitization, Immunologic; D006706:Homeostasis; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000473:pathology / Q000628:therapy; D016176:T-Lymphocyte Subsets / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D022223:Vaccines, Subunit / Q000276:immunology* / Q000627:therapeutic use
D000485:Allergens; D001324:Autoantigens; D016207:Cytokines; D022223:Vaccines, Subunit