title: Improving clinical trial design for inquiries into the mechanisms of cyst growth in ADPKD.
abstract: Accurate and reliable estimates of kidney and cyst volume, the hallmark of disease progression in ADPKD are now available. These powerful and exciting tools make it possible to consider both short and long term randomized clinical trials in ADPKD at various stages of disease. Highlights of the work by Kistler and colleagues are now provided.
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia 30322, USA. Arlene.chapman@emoryhealthcare.org
authors.forename: Arlene B
authors.initials: AB
authors.lastname: Chapman
mesh_terms: D002985:Clinical Protocols / Q000592:standards*; D003460:Crystallization; D003560:Cysts / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D006984:Hypertrophy; D016891:Polycystic Kidney, Autosomal Dominant / Q000473:pathology*