High-resolution solid-state NMR spectroscopy of protons with homonuclear dipolar decoupling schemes under magic-angle spinning.
High-resolution NMR spectroscopy of (1)H spins in the solid state is normally rendered difficult due to the strong homonuclear (1)H-(1)H dipolar couplings. Even under very high-speed magic-angle spinning (MAS) at ca. 60-70kHz, these couplings are not completely removed. An appropriate radiofrequency pulse scheme is required to average out the homonuclear dipolar interactions in combination with MAS to get high-resolution (1)H NMR spectrum in solid state. Several schemes have been introduced in the recent past with a variety of applications also envisaged. Development of some of these schemes has been made possible with a clear understanding of the underlying spin physics based on bimodal Floquet theory. The utility of these high-resolution pulse schemes in combination with MAS has been demonstrated for spinning speeds of 10-65kHz in a range of (1)H Larmor frequencies from 300 to 800MHz.
Madhu
P K
PK
Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400 005, India. madhu@tifr.res.in
D000465:Algorithms; D003198:Computer Simulation; D005544:Forecasting; D008956:Models, Chemical; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011522:Protons; D012680:Sensitivity and Specificity; D013113:Spin Labels
D011522:Protons; D013113:Spin Labels