title: Environmental tobacco smoke exposure and child behaviors.
abstract: BACKGROUND
  Emerging evidence suggests that exposure to environmental tobacco smoke (ETS) may be linked with behavior problems in childhood, but previous research has relied primarily on parent report of exposure, and results are inconclusive.
  
  
  OBJECTIVE
  To investigate the relationship between exposure to ETS and child behavior problems among children with asthma.
  
  
  METHODS
  The sample included 220 children who were enrolled in an asthma intervention trial and regularly exposed to ETS at home. Serum cotinine was used to measure exposure to tobacco smoke, and behavior problems were assessed by parent report on the Behavior Assessment System for Children. Covariates in adjusted analyses included: sex, age, race, asthma severity, asthma medication, maternal education, prenatal tobacco exposure, maternal depression, and Home Observation for Measurement of the Environment score.
  
  
  RESULTS
  Child behavior problems increased with increasing exposure to ETS. A stratified analysis of boys and girls separately indicated higher exposure among girls, but behavior problems were statistically significantly associated with exposure only in boys. Increasing behavior problems included externalizing behavior problems (beta= 2.23, p =.02) such as hyperactivity and aggression, internalizing behavior problems (beta= 2.19, p= .01) such as depression, and behavior symptoms (beta= 2.55, p= .01).
  
  
  CONCLUSIONS
  Among children with asthma, exposure to ETS is related to increased child behavior problems among boys.
authors.affiliation: Department of Pediatrics, Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. kimberly.yolton@cchmc.org
authors.forename: Kimberly
authors.initials: K
authors.lastname: Yolton
authors.forename: Jane
authors.initials: J
authors.lastname: Khoury
authors.forename: Richard
authors.initials: R
authors.lastname: Hornung
authors.forename: Kim
authors.initials: K
authors.lastname: Dietrich
authors.forename: Paul
authors.initials: P
authors.lastname: Succop
authors.forename: Bruce
authors.initials: B
authors.lastname: Lanphear
mesh_terms: D000374:Aggression / Q000502:physiology / Q000523:psychology; D001249:Asthma / Q000150:complications / Q000503:physiopathology*; D002648:Child; D002653:Child Behavior Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D002851:Chromatography, High Pressure Liquid; D003367:Cotinine / Q000097:blood; D003863:Depression / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D004311:Double-Blind Method; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D010919:Placebos; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D014028:Tobacco Smoke Pollution; D014481:United States / Q000453:epidemiology
chemical_list: D010919:Placebos; D014028:Tobacco Smoke Pollution; D003367:Cotinine