title: [Therapeutic approaches for breast carcinoma].
abstract: With increasing incidence of breast cancer its prevalence also increases. Improvement of therapeutic approaches recently introduced led to improved treatment outcomes. The introduction of taxanes into the adjuvant treatment prolongs the overall survival (OS) of the patients. Third generation of aromatase inhibitors appear better than tamoxifen in the adjuvant treatment of postmenopausal women. New anticancer drugs in combination with bevacizumab and trastuzumab have brought new possibilities in treatment of patients with metastatic breast cancer: their use apparently increases the rate of treatment response and overall survival.
authors.affiliation: Masaryküv Onkologický Ustav Brno. petrakova@mou.cz
authors.forename: K
authors.initials: K
authors.lastname: Petrakova
authors.forename: J
authors.initials: J
authors.lastname: Růzicková
authors.forename: V
authors.initials: V
authors.lastname: Fait
mesh_terms: D001943:Breast Neoplasms / Q000628:therapy*; D005260:Female; D006801:Humans