Susac's syndrome: intratympanic therapy for hearing loss and a review of the literature.
Two cases of Susac's Syndrome are presented with a discussion of treatment modalities for the associated severe sensorineural deafness. Patients were managed with high dose oral steroids, anticoagulants and immunosuppressive drugs. The addition of intratympanic methylprednisolone injections were added to one patient's regimen with initial improvement but subsequent relapse and progression to profound deafness. The management of Susac's syndrome is difficult and still in need of innovative methods as the standard treatment continues to be ineffective in the long term.
Crawley
Brianna K
BK
Division of Otolaryngology/Head and Neck Surgery, Department of Surgery, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
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Abby
A
Canto
Cecilia
C
Harris
Jeffrey P
JP
D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D015356:Retinal Artery Occlusion / Q000150:complications / Q000175:diagnosis; D013577:Syndrome; D014432:Tympanic Membrane
D005938:Glucocorticoids; D007166:Immunosuppressive Agents