[Incidence of metabolic disorders in patients with essential hypertension and patients with primary aldosteronism].
OBJECTIVE
To compare the incidence of metabolic disorders (MS) in patients with primary aldosteronism (PA) and essential hypertension (EH).


METHODS
MS prevalence was observed in 200 EH patients (male 104) and 220 PA patients (male 117) hospitalized to our hospital from August 2005 to March 2007.


RESULTS
(1) The prevalence of MS in PA group was significantly higher than that of EH group (47.3% vs. 31.5%, P = 0.009). (2) Blood pressure was significantly higher in PA group than that of EH [SBP: (150.67 +/- 15.45) mm Hg vs. (145.69 +/- 17.13) mm Hg, P = 0.042; DBP: (93.03 +/- 10.51) mm Hg vs. (85.83 +/- 14.44) mm Hg, P = 0.037]. (3) Incidences of abdominal obesity (86.8% vs. 78.5%, P = 0.024) and insulin resistance (insulin sensitivity index: 42.42 +/- 16.11 vs. 49.58 +/- 22.43, P = 0.008) were significantly higher in PA group than in EH group.


CONCLUSIONS
The prevalence of MS in hospitalized PA patients was significantly higher than that of EH patients characterized by prevalent abdominal obesity, insulin resistant and severe hypertension.
Gong
Yan-chun
YC
Department of Hypertension, Ruijin Hospital Affiliated to Jiaotong University, Shanghai 200025, China.
Guo
Rui-Min
RM
Chen
Shao-xing
SX
Chu
Shao-li
SL
Guo
Ji-zhen
JZ
Zhu
Ding-liang
DL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000453:epidemiology / Q000378:metabolism*; D006973:Hypertension / Q000453:epidemiology / Q000378:metabolism*; D015994:Incidence; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged