title: Permeability evaluation of 45S5 Bioglass-based scaffolds for bone tissue engineering.
abstract: Permeability is a key parameter for microstructural design of scaffolds, since it is related to their capability for waste removal and nutrients/oxygen supply. In this framework, Darcy's experiments were carried out in order to determine the relationship between the pressure drop gradient and the fluid flow velocity in Bioglass-based scaffolds to obtain the scaffold's permeability. Using deionised water as working fluid, the measured average permeability value on scaffolds of 90-95% porosity was 1.96 x 10(-9) m(2). This value lies in the published range of permeability values for trabecular bone.
authors.affiliation: Aragon Institute of Engineering Research (I3A), Group of Structural Mechanics and Materials Modelling, Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Universidad de Zaragoza, 50018 Zaragoza, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Ochoa
authors.forename: José A
authors.initials: JA
authors.lastname: Sanz-Herrera
authors.forename: José M
authors.initials: JM
authors.lastname: García-Aznar
authors.forename: Manuel
authors.initials: M
authors.lastname: Doblaré
authors.forename: Darmawati Mohamad
authors.initials: DM
authors.lastname: Yunos
authors.forename: Aldo R
authors.initials: AR
authors.lastname: Boccaccini
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D018786:Bone Substitutes / Q000737:chemistry; D001842:Bone and Bones / Q000378:metabolism*; D002516:Ceramics / Q000737:chemistry*; D005898:Glass; D010539:Permeability; D013499:Surface Properties; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; C425330:bioactive glass 45S5