title: [Hypotensive effect of oxatriazolium-5-olate derivative].
abstract: Intravenous administration of azasidnon-6 (oxatriazolium-5-olate derivative) induces prolonged dose-dependent decrease in arterial blood pressure in awake Wistar and SHR rats. Hypotensive effects of azasidnon-6 in SHR rats is significantly higher during inhibition of endogenous NO synthesis.
authors.forename: M M
authors.initials: MM
authors.lastname: Artem'eva
authors.forename: A B
authors.initials: AB
authors.lastname: Postnikov
authors.forename: O V
authors.initials: OV
authors.lastname: Akinfrieva
authors.forename: I L
authors.initials: IL
authors.lastname: Daliger
authors.forename: S A
authors.initials: SA
authors.lastname: Shevelev
authors.forename: O S
authors.initials: OS
authors.lastname: Medvedev
authors.forename: N A
authors.initials: NA
authors.lastname: Medvedeva
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D003692:Delayed-Action Preparations / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism; D051381:Rats; D011918:Rats, Inbred SHR; D017208:Rats, Wistar; D014230:Triazoles / Q000494:pharmacology*
chemical_list: D000959:Antihypertensive Agents; D003692:Delayed-Action Preparations; D014230:Triazoles; D009569:Nitric Oxide