title: [Usefulness of hepatic arterial infusion chemotherapy for the patients with synchronous liver metastases from colorectal cancer].
abstract: We analyzed the results of hepatic arterial infusion chemotherapy (HAIC) for 21 patients with synchronous liver metastases from colorectal cancer for the last ten years to investigate the usefulness of HAIC for those patients. In 7 cases with resection of liver metastases, the median survival time (MST) was 49 months, mean survival time was 56.3 months and a 5-year survival rate was 43%. In 14 cases without resection of liver metastases, 2 cases had complete response (CR), 8 cases had partial response (PR), 4 cases had stable disease (SD), and the response rate was 71%. There was a significant difference in the survival time of each response. MST was 27 months, and mean survival time was 38.5 months. According to the usefulness of HAIC for the patients with synchronous liver metastases from colorectal cancer, it seems that HAIC with effective general chemotherapy will have better results than HAIC.
authors.affiliation: Dept. of Surgery, National Hospital Organization Yonago Medical Center.
authors.forename: Osamu
authors.initials: O
authors.lastname: Kimura
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Kuroda
authors.forename: Akemi
authors.initials: A
authors.lastname: Iwamoto
authors.forename: Nariyuki
authors.initials: N
authors.lastname: Yamane
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Hamazoe
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000453:epidemiology / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015996:Survival Rate