Anti-Candida activity of alpha-melanocyte-stimulating hormone (alpha-MSH) peptides.
Previously, alpha-MSH, a 13-amino acid neuropeptide and the tripeptide alpha-MSH have been shown to possess potent antimicrobial properties. We performed microplate based growth inhibition assays on C. albicans with alpha-MSH, but could not observe any growth inhibiting effect. Repeating the originally published assay with different C. albicans strains, we detected a mild growth inhibiting effect of 100 microM alpha-MSH, but again no effect of alpha-MSH.
Rauch
Isabella
I
Holzmeister
Simone
S
Kofler
Barbara
B
D002176:Candida albicans / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D000521:alpha-MSH / Q000494:pharmacology*
D000521:alpha-MSH