title: Reversion of influenza A (H3N2) virus from amantadine resistant to amantadine sensitive by further reassortment in Japan during the 2006-to-2007 influenza season.
abstract: In the 2006-to-2007 influenza season, amantadine-sensitive strains were found among the N-lineage influenza A (H3N2) viruses, which were previously believed to be associated with amantadine resistance. Whole-genome sequencing results indicated that this was due to a further reassortment event.
authors.affiliation: Tohoku University Graduate School of Medicine, Aoba-ku, Sendai 980-8575, Japan. furusey@mail.tains.tohoku.ac.jp
authors.forename: Yuki
authors.initials: Y
authors.lastname: Furuse
authors.forename: Akira
authors.initials: A
authors.lastname: Suzuki
authors.forename: Taro
authors.initials: T
authors.lastname: Kamigaki
authors.forename: Midori
authors.initials: M
authors.lastname: Shimizu
authors.forename: Naoko
authors.initials: N
authors.lastname: Fuji
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Oshitani
mesh_terms: D000547:Amantadine / Q000494:pharmacology*; D000998:Antiviral Agents / Q000494:pharmacology*; D016679:Genome, Viral; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects* / Q000235:genetics*; D007251:Influenza, Human / Q000821:virology*; D007564:Japan; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D016865:Reassortant Viruses / Q000187:drug effects* / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D000998:Antiviral Agents; D012367:RNA, Viral; D000547:Amantadine