title: [Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter].
abstract: We present two cases of proarrhythmia after propafenone treatment. In the first case slowing of the flutter cycle length from 205 ms to 290 ms resulted in a change from well tolerated two to one atrioventricular conduction to one to one conduction with hypotension and presyncope. In the second case organization of atrial fibrillation to atypical atrial flutter and use-dependent left bundle branch block resulted in fast broad QRS tachycardia that mimicked ventricular tachycardia.
authors.affiliation: I Klinika Kardiologii i Nadciśnienia Tetniczego, ul. Kopernika 17, 31-501 Kraków. mcjastrz@cyf-kr.edu.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Jastrzebski
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000175:diagnosis; D001281:Atrial Fibrillation / Q000139:chemically induced / Q000188:drug therapy*; D001282:Atrial Flutter / Q000139:chemically induced / Q000188:drug therapy*; D002037:Bundle-Branch Block / Q000139:chemically induced*; D004562:Electrocardiography; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000009:adverse effects*; D013575:Syncope / Q000139:chemically induced; D013610:Tachycardia / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000889:Anti-Arrhythmia Agents; D011405:Propafenone