title: Reversible grasp reflexes in normal pressure hydrocephalus.
abstract: We present two cases of normal pressure hydrocephalus in combination with grasp reflexes. In both cases the grasp reflexes disappeared following high volume cerebrospinal fluid removal. In one of the cases the grasp reflexes returned over a period of weeks but again resolved following definitive cerebrospinal fluid shunting surgery, and remained absent until final follow up at 9 months. We hypothesise that resolving grasp reflexes following high volume CSF removal has both diagnostic and prognostic value in normal pressure hydrocephalus, encouraging larger studies on the relevance of primitive reflexes in NPH.
authors.affiliation: Wales Epilepsy Research Network, Institute of Life Sciences, Singleton Park, Swansea University, SA2 8PP, UK. Rhys-Thomas@doctors.org.uk
authors.forename: Rhys H
authors.initials: RH
authors.lastname: Thomas
authors.forename: Luke
authors.initials: L
authors.lastname: Bennetto
authors.forename: Mark T
authors.initials: MT
authors.lastname: Silva
mesh_terms: D000369:Aged, 80 and over; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects* / Q000379:methods; D005260:Female; D018737:Hand Strength; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012021:Reflex, Abnormal; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome