Human hepatocyte transplantation overview.
The interest in hepatocyte transplantation has been growing continuously in recent years and this treatment may represent an alternative clinical approach for patients with acute liver failure and liver-based metabolic disorders. This chapter presents an overview of liver cell transplantation, from the basic research to human experience. It summarizes the pre-clinical studies and present status of clinical hepatocyte transplantation and identifies some possible areas of future research in this area.
Puppi
Juliana
J
Institute of Liver Studies, King's College London School of Medicine London, UK.
Dhawan
Anil
A
D000818:Animals; D002469:Cell Separation; D005069:Evaluation Studies as Topic; D022781:Hepatocytes / Q000166:cytology / Q000637:transplantation*; D006801:Humans; D017114:Liver Failure, Acute / Q000628:therapy; D016031:Liver Transplantation / Q000379:methods* / Q000639:trends; D008659:Metabolic Diseases / Q000628:therapy; D014015:Tissue Banks / Q000639:trends