[Genotypes of hepatitis B virus in Henan Luohe area].
OBJECTIVE
To determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area.


METHODS
Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3.


RESULTS
About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree.


CONCLUSIONS
The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.
Wang
Fu-Qing
FQ
Luohe Medical College, Luohe 462002, China.
Huang
Xiao-Lei
XL
Li
Ai-Qin
AQ
Wang
Jian-Guo
JG
Zhang
Fu-Hua
FH
Cui
Yan-Bing
YB
Yi
Yao
Y
Chen
Si-Yong
SY
D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D005838:Genotype; D006509:Hepatitis B / Q000821:virology*; D006514:Hepatitis B Surface Antigens / Q000097:blood / Q000235:genetics; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D055815:Young Adult
D006514:Hepatitis B Surface Antigens