Atypical femoral fractures, bisphosphonates, and adult hypophosphatasia.
Lateral subtrochanteric femoral pseudofractures occurring in adults with osteomalacia from hypophosphatasia and X-linked hypophosphatemia support the hypothesis that atypical femoral fractures in osteoporosis treated with bisphosphonates also result from low bone turnover.
Whyte
Michael P
MP
Division of Bone and Mineral Diseases, Washington University School of Medicine at Barnes-Jewish Hospital, and Center for Metabolic Bone Disease and Molecular Research, Shriners Hospitals for Children, St. Louis, Missouri, USA. mwhyte@shrinenet.org
D000328:Adult; D004164:Diphosphonates / Q000627:therapeutic use*; D053098:Familial Hypophosphatemic Rickets / Q000150:complications*; D005264:Femoral Fractures / Q000150:complications* / Q000517:prevention & control*; D040181:Genetic Diseases, X-Linked; D006801:Humans
D004164:Diphosphonates