[Serum triglyceride is an independent risk factor for acute coronary heart disease events in 35 - 64 years old Chinese-Chinese Multi-provincial Cohort Study.].
OBJECTIVE
To evaluate the association between serum triglyceride (TG) and the cardiovascular diseases (CVD) risk in Chinese population.


METHODS
A total of 30, 378 men and women aged 35 - 64 years old were recruited in the Chinese-Chinese Multi-provincial Cohort Study (CMCS). The serum TG and other CVD risk factors were measured. All subjects were followed up annually or biannually for acute CVD events from 1992 to 2004. A Cox regression model was established to identify the association between TG and risk of CVD events.


RESULTS
The accumulative incidence rate of acute coronary heart disease (CHD) events increased from 62.6/100 000 in the low TG groups to 168.4/100 000 in the high TG group divided by the quartile. TG was identified as an independent risk factor for CHD after adjustment for the confounding risk factors by a Cox regression model. Compared subjects with TG < 0.81 mmol/L, CHD risk increased 81% and 59% in subjects with TG 1.15 - 1.59 mmol/L and TG >/= 1.60 mmol/L, respectively (all P < 0.05). There was no significant association between TG level and the risks of hemorrhagic and ischemic stroke events (P > 0.05).


CONCLUSIONS
Serum TG is an independent risk factor for acute CHD events in Chinese population aged 35 - 64.
Wang
Miao
M
Department of Epidemiology, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China.
Zhao
Dong
D
Wang
Wei
W
Liu
Jing
J
Liu
Jun
J
Liu
Sa
S
Sun
Jia-Yi
JY
Qin
Lan-Ping
LP
Wu
Zhao-Su
ZS
D015331:Cohort Studies; D003327:Coronary Disease / Q000453:epidemiology; D006801:Humans; D017202:Myocardial Ischemia; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides