Comparison of efficacy between continuous hemodiafiltration with a PMMA membrane hemofilter and a PAN membrane hemofilter in the treatment of a patient with septic acute renal failure.
The aim of this study was to investigate whether PMMA-CHDF in the treatment of a patient with septic acute renal failure (septic ARF) is clinically relevant. Thirteen patients were treated with PMMA-CHDF. Thirteen patients were treated with PAN-CHDF. The urinary output significantly increased in PMMA-CHDF group following 24h of the treatment (p<0.05), whereas those did not improve in PAN-CHDF group. The 28-day survival was 84.6% in PMMA-CHDF group and 38.5% in PAN-CHDF group, respectively (p<0.05). We can assume that the cytokine modulation with PMMA-CHDF in the treatment of patients with septic ARF is clinically relevant.
Matsuda
Kenichi
K
Department of Emergency and Critical Care Medicine, University of Yamanashi School of Medicine, 1110 Shimokato Chuo, Yamanashi 409-3898, Japan. matsudak@yamanashi.ac.jp
Moriguchi
Takeshi
T
Harii
Norikazu
N
Goto
Junko
J
D000180:Acrylic Resins; D000181:Acrylonitrile / Q000031:analogs & derivatives*; D058186:Acute Kidney Injury / Q000150:complications / Q000401:mortality / Q000628:therapy*; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D017583:Hemodiafiltration; D006801:Humans; D008297:Male; D008875:Middle Aged; D019904:Polymethyl Methacrylate; D012189:Retrospective Studies; D018805:Sepsis / Q000150:complications / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate
D000180:Acrylic Resins; C016892:AN-69; D019904:Polymethyl Methacrylate; D000181:Acrylonitrile