[Evaluation of tissue strain and strain rate imaging for left heart function in children with systemic lupus erythematosus].
OBJECTIVE
To investigate the diagnostic value of the tissue strain imaging in myocardial dysfunction in children with systemic lupus erythematosus (SLE).


METHODS
24 patients with SLE and 32 healthy controls underwent conventional and tissue Doppler echocardiography. Peak strain and strain rate value during systolic and diastolic phases as well as E/A, LVFS, LVEF were measured in both SLE and the control group subjects.


RESULTS
The E/A, LVFS and LVEF did not significantly differ between SLE children and controls (P > 0.05). The systolic peak strains and strain rates of SLE children were lower than those of the controls but there was no significant difference (P > 0.05). The diastolic peak strains and strain rates of SLE children were significantly lower than those of the controls (P < 0.01). The diastolic peak strains and strain rates of anticardiolipin antibodies (aCL) positive children were significantly lower than the aCL negative ones (P < 0.05).


CONCLUSIONS
Strain and strain rate combined with aCL could sensitively detect myocardial dysfunction of children with SLE.
Liang
Hao
H
Department of Echocardiography, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Zhu
Mei
M
Feng
Juan
J
Zhang
Nan
N
Guo
Wen-bin
WB
D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left