title: [The efficacy of surgical resection and chemo-endocrine therapy for patients with local recurrence or axillary lymph node metastasis of breast cancer].
abstract: We evaluated a surgical resection and chemo-endocrine therapy and prognosis for patients with local recurrence or axillary lymph node metastasis of breast cancer. Twenty-one patients with local recurrence or axillary lymph node metastasis without a distant metastasis were enrolled in this study. Thirteen of the 21 patients underwent a surgical resection. Resection of recurrent lesion in residual breast after breast conserving therapy for six of the 13 patients, axillary lymph node dissection (ALND) for four, and resection of thoracic wall lesion for three were performed. Five of the patients who underwent resection of residual breast lesion, four of the patients who underwent ALND and two of the patients who underwent resection of thoracic wall lesion have survived. One of the patients who underwent resection of residual breast lesion and one of the patients who underwent resection of thoracic wall lesion were dead. In eight non-operable patients, five were dead and three have survived. Median recurrence free interval was 24 months in operable patients and 27 months in non-operable patients. Median survival time after recurrence was 29 months in operable patients and 12 months in non-operable patients. The surgical with chemo-endocrine therapy promises to control well to local recurrence or axillary lymph node metastasis for the patients we selected.
authors.affiliation: Dept. of Surgery, Saiseikai Senri Hospital.
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Hojo
authors.forename: Setsuko
authors.initials: S
authors.lastname: Yoshioka
authors.forename: Akiko
authors.initials: A
authors.lastname: Yoshioka
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Fujie
authors.forename: Hiroki
authors.initials: H
authors.lastname: Fukunaga
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Okada
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Ota
authors.forename: Wakio
authors.initials: W
authors.lastname: Endo
authors.forename: Yoshiichi
authors.initials: Y
authors.lastname: Maeura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D004703:Endocrine System / Q000187:drug effects*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000601:surgery*; D011379:Prognosis; D015996:Survival Rate