title: [Hepatocellular carcinoma with metastasis to the cavernous sinus of skull base causing ptosis].
abstract: The cavernous sinus of skull base is a extremely rare metastastatic site for hepatocellular carcinoma (HCC). A 51-year-old man was diagnosed with HCC by liver biopsy and palliative radiotherapy on HCC including main portal vein was performed. One month later, he was admitted due to sudden onset ptosis. Neurologic findings were normal except for abnormal movement of right eye, and it raised the possibility of abnormality in the right occulomotor, trochlear and the abducens nerves. Contrast-enhanced CT scan of brain showed a mass with homogeneous enhancement involving the right cavernous sinus. T2-weighted axial MR images demonstrated a homogeneous mass with intermediate signal intensity, and contrast-enhanced axial T1-weighted MR images demonstrated a mass with homogeneous enhancement in the right cavernous sinus. We describe a case of HCC metastasis to the cavernous sinus with symptoms of ptosis and disturbance of right eyeball movement.
authors.affiliation: Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
authors.forename: Sang Jung
authors.initials: SJ
authors.lastname: Kim
authors.forename: Hyung Joon
authors.initials: HJ
authors.lastname: Kim
authors.forename: Hyun Woong
authors.initials: HW
authors.lastname: Lee
authors.forename: Chang Hwan
authors.initials: CH
authors.lastname: Choi
authors.forename: Jung Uk
authors.initials: JU
authors.lastname: Kim
authors.forename: Jae Hyuk
authors.initials: JH
authors.lastname: Do
authors.forename: Jae Kyu
authors.initials: JK
authors.lastname: Kim
authors.forename: Sae Kyung
authors.initials: SK
authors.lastname: Chang
mesh_terms: D001763:Blepharoptosis / Q000209:etiology* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000175:diagnosis* / Q000556:secondary*; D002426:Cavernous Sinus / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000473:pathology; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000556:secondary*; D014057:Tomography, X-Ray Computed