Neurosarcoidosis: clinical features, diagnosis, and management.
Sarcoidosis is a multisystemic granulomatous disease, which uncommonly affects nervous system. However, when present, it may affect both central and peripheral nervous systems and potentially mimics other chronic diseases of the nervous system. Pathogenesis of neurosarcoidosis remains largely unknown, and its diagnosis and management pose serious challenges to clinicians. Early diagnosis and aggressive treatment of neurosarcoidosis are necessary to produce satisfactory clinical outcomes. This review discusses clinical manifestations, current diagnostic studies, and currently available modalities for management of neurosarcoidosis.
Schwendimann
Robert N
RN
Departments of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
Harris
Meghan K
MK
Elliott
Debra G
DG
Menon
Uma
U
Gonzalez-Toledo
Eduardo
E
Zivadinov
Robert
R
Pressly
Thomas A
TA
Kelley
Roger E
RE
Hoque
Romy
R
Fowler
Marjorie
M
Maghzi
Amir H
AH
Etemadifar
Masoud
M
Saadatnia
Mohammad
M
Minagar
Alireza
A
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D019635:Neurosurgical Procedures; D011379:Prognosis; D012507:Sarcoidosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents