title: Clinical correlates of generalized worry in multiple sclerosis.
abstract: Anxiety disorders are common in multiple sclerosis (MS). Chronic worry is the defining feature of generalized anxiety. Despite this, only one study has examined the impact of chronic worry in MS. The present investigation explored the relationship between excessive worry and common physical, emotional, and neuropsychological symptoms in a community-based sample of 50 patients with relapsing-remitting and secondary progressive MS. As expected, MS patients reported significantly more worry than a group of 45 healthy controls. Correlational analyses revealed that MS patients' elevated worry was associated with fatigue, sleep disturbance, problem-solving deficits, pain, and disability status. Follow-up analyses indicated that worry and anxiety may represent related but distinct constructs. Clinicians are urged to regularly monitor and treat pathological worry in MS.
authors.affiliation: University of Missouri-Kansas City College of Arts and Sciences, 4825 Troost Building, Suite 111-G, 5100 Rockhill Road, Kansas City, MO 64110, USA. Brucejm@umkc.edu
authors.forename: Jared M
authors.initials: JM
authors.lastname: Bruce
authors.forename: Peter
authors.initials: P
authors.lastname: Arnett
mesh_terms: D000328:Adult; D001007:Anxiety / Q000209:etiology*; D003072:Cognition Disorders / Q000209:etiology*; D004185:Disability Evaluation; D004644:Emotions / Q000502:physiology; D005221:Fatigue / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000523:psychology*; D009483:Neuropsychological Tests; D010146:Pain / Q000209:etiology; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000209:etiology; D013223:Statistics as Topic / Q000379:methods*; D011795:Surveys and Questionnaires