B:2a:p1.5 meningococcal strains likely arisen from capsular switching event still spreading in Spain.
Eighteen clustered cases of meningococcal disease associated with B:2a:P1.5 strains doubled the annual incidence up to 4.3 x 10(5) in Navarra, Spain, in 2007. Eleven percent of cases were fatalities, and 74% of cases were individuals 10 to 24 years old. This is the third cluster associated with this strain in northern Spain since 2001.
Castilla
Jesús
J
Instituto de Salud Pública de Navarra, Pamplona, Spain.
Vázquez
Julio A
JA
Salcedo
Celia
C
García Cenoz
Manuel
M
García Irure
José Javier
JJ
Torroba
Luis
L
Beristain
Xabier
X
Abad
Raquel
R
Barricarte
Aurelio
A
D002648:Child; D016000:Cluster Analysis; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D015994:Incidence; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000401:mortality; D038541:Neisseria meningitidis, Serogroup B / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
D004269:DNA, Bacterial