title: Fixed and mobile bearing total knee arthroplasty--influence on wear generation, corresponding wear areas, knee kinematics and particle composition.
abstract: BACKGROUND
  Several studies in literature are dealing with a direct comparison between fixed and mobile bearing knee replacements, but to our knowledge there is no published data comparing the wear behaviour of the two design principles based on the same femur and superior gliding surface geometry. The objective of our study was to investigate a fixed and mobile bearing knee design with identical femoral articulation in regard to wear, tibio-femoral kinematics and particle size distribution.
  
  
  METHODS
  In vitro wear simulation according to ISO 14243-1 has been performed with the Columbus knee system (Aesculap, Tuttlingen) in the configurations fixed and mobile bearing for five million cycles on a customized four station knee wear simulator. The tests were running under force control and the tibio-femoral kinematics were assessed. A particle analysis has been undergone after each inspection interval when the lubricant was replaced.
  
  
  RESULTS
  Due to the additional wear in the tibial articulation of the mobile bearing design the mean gravimetric wear rates are not statistically different between the two groups. Apart of that there is a substantial reduction in the amount of wear per area unit for the mobile versus the fixed bearing gliding surfaces. Both groups show comparable tibio-femoral kinematics and a similar wear debris morphology.
  
  
  CONCLUSIONS
  Our investigation of a fixed and mobile bearing knee design with identical femoral articulation demonstrates that there are no significant differences in wear rate, resulting kinematics and polyethylene particle release. Therefore it can be recommended that surgeons decision for one or the other design principle should be based on the individual patient profile.
authors.affiliation: Aesculap AG Research and Development, Am Aesculap-Platz, D-78532 Tuttlingen, Germany. thomas.grupp@aesculap.de
authors.forename: T M
authors.initials: TM
authors.lastname: Grupp
authors.forename: C
authors.initials: C
authors.lastname: Kaddick
authors.forename: J
authors.initials: J
authors.lastname: Schwiesau
authors.forename: A
authors.initials: A
authors.lastname: Maas
authors.forename: S D
authors.initials: SD
authors.lastname: Stulberg
mesh_terms: D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology* / Q000601:surgery*; D007720:Knee Prosthesis; D008954:Models, Biological; D010316:Particle Size; D011475:Prosthesis Failure