title: Velocity propagation of early diastole is a valuable tool for left ventricular remodelling after the first myocardial infarction.
abstract: OBJECTIVE
  Velocity propagation (Vp) of early diastole is a known method for the evaluation of left ventricular (LV) diastolic function. Our purpose was to determine whether Vp is a valuable tool to characterize patients after acute myocardial infarction and LV remodelling (LVR).
  
  
  METHODS
  M-mode, two-dimensional and Doppler echocardiography were performed in 71 patients within the first 2 days, 1, 3 and 6 months after acute myocardial infarction. We measured the left atrium, LV diameters and volumes, peak early and late velocity (E, A) deceleration time, Vp, annular velocity (e) and calculated E/e. The patients were divided in two groups: (A) without early LVR (n=39) and (B) with early LVR (n=32).
  
  
  RESULTS
  In the first evaluation, Vp was similar in both groups (36.37 vs. 35.49 cm/s, P=0.513). Late LVR (LLVR) (44%) had developed in patients from group A with significantly lower early Vp compared with patients without LLVR (31.52 vs. 40.12 cm/s, P=0.001), with persist values even after 6 months (29.41 vs. 40.85 cm/s, P=0.001). The values of Vp were similar in the first 2 days in patients from group B with developing (78%) and nondeveloping LLVR (35.29 vs. 36.60 cm/s, P=0.614). Differences became significant after 6 months (31.71 vs. 41.80 cm/s, P=0.001). The values of Vp of 35 cm/s or less from the first week in both groups correlated with LLVR (B=3.27, P=0.015). Changing of LV volumes significantly correlated with Vp; for end-diastolic volume/body surface area (r=0.21, P=0.041) and end-systolic volume/body surface area (r=0.30, P=0.014).
  
  
  CONCLUSIONS
  In this study, Vp was the only valuable Doppler echocardiographic tool that reflected early LVR and LLVR.
authors.affiliation: University Clinical Center Dr Dragisa Misovic-Dedinje, Belgrade, Serbia.
authors.forename: Vera P
authors.initials: VP
authors.lastname: Celic
authors.forename: Milica N
authors.initials: MN
authors.lastname: Dekleva
authors.forename: Nada D
authors.initials: ND
authors.lastname: Kostic
authors.forename: Mirko D
authors.initials: MD
authors.lastname: Colic
authors.forename: Jelena M
authors.initials: JM
authors.lastname: Suzic
authors.forename: Nenad J
authors.initials: NJ
authors.lastname: Radivojevic
authors.forename: Anka R
authors.initials: AR
authors.lastname: Majstorovic
authors.forename: Biljana D
authors.initials: BD
authors.lastname: Pencic
mesh_terms: D001830:Body Surface Area; D003971:Diastole; D018618:Echocardiography, Doppler, Color; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015588:Observer Variation; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D013318:Stroke Volume; D013997:Time Factors; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling