Pseudohypopyon: Extramedullary relapse of acute myelogenous leukemia with poor prognosis.
An 11-month-old female presented to the emergency department with a 2-week history of fever, increasing fussiness, emesis, and decreased urine output. She was diagnosed with acute myelogenous leukemia. Systemic chemotherapy with intensified intrathecal cytarabine was started, and the patient achieved a clinical remission after the first course of induction. Towards the end of her second course of induction she developed pseudohypopyon in each eye on consecutive days, heralding a central nervous system relapse.
Petersen
William C
WC
Department of Pediatrics, The Children's Hospital, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA.
Schlis
Krysta D
KD
Braverman
Rebecca S
RS
Carlson
Ingrid
I
Liang
Xiayuan
X
Wang
Michael
M
D000867:Anterior Chamber / Q000473:pathology*; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D005128:Eye Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007223:Infant; D007278:Injections, Spinal; D015479:Leukemia, Myelomonocytic, Acute / Q000175:diagnosis* / Q000188:drug therapy; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000628:therapy; D011379:Prognosis; D013492:Suppuration / Q000175:diagnosis
D000964:Antimetabolites, Antineoplastic; D003561:Cytarabine