title: Thought disorder and executive dysfunction in patients with schizophrenia.
abstract: Although, impairment of executive functioning is often reported in schizophrenia, its association with thought disorder has not been fully determined. The present study examined the relationships between positive thought disorder assessed using the Harrow's Thought Disorder Scale (Harrow's scale) and executive function by Wisconsin Card Sorting Test (WCST) in 27 inpatients with schizophrenia. Age at onset exhibited a significant negative correlation with Wechsler Adult Intelligence Scale comprehension test score of Harrow's scale and a significant positive correlation with percentage of perseverative errors on the WCST. No significant correlations were found between parameters of positive thought disorder and executive function. Thought disorder and executive function may play different roles in the pathophysiology of schizophrenia.
authors.affiliation: Department of Psychiatry, Showa University School of Medicine, Tokyo, Japan.
authors.forename: Toshimi
authors.initials: T
authors.lastname: Owashi
authors.forename: Akira
authors.initials: A
authors.lastname: Iwanami
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Nakagome
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Higuchi
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Kamijima
mesh_terms: D000328:Adult; D017668:Age of Onset; D044466:Asian People; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology*; D003657:Decision Making / Q000502:physiology; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007360:Intelligence / Q000502:physiology; D008297:Male; D008606:Mental Processes / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013850:Thinking / Q000502:physiology; D055815:Young Adult