title: Synthesis of oxindoles by tandem Heck-reduction-cyclization (HRC) from a single bifunctional, in situ generated Pd/C catalyst.
abstract: A tandem sequence involving palladium-catalyzed sequential Heck-reduction-cyclization transformations in mild conditions has been developed for the synthesis of oxindoles. The protocol involves inexpensive reagents and does not require any additives such as base or ligands.
authors.affiliation: Universite de Bordeaux, CNRS, Institut des Sciences Moleculaires, 351 Cours de la Liberation, 33405 Talence Cedex, France. fx.felpin@ism.u-bordeaux1.fr
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Felpin
authors.forename: Oier
authors.initials: O
authors.lastname: Ibarguren
authors.forename: Luma
authors.initials: L
authors.lastname: Nassar-Hardy
authors.forename: Eric
authors.initials: E
authors.lastname: Fouquet
mesh_terms: D000179:Acrylates / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry
chemical_list: D000179:Acrylates; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D010165:Palladium