title: Successful prolonged resuscitation involving the use of tenecteplase without neurological sequelae.
abstract: Prehospital cardiac arrest is associated with a very poor prognosis. We report a case of complete neurological recovery after prolonged resuscitation involving the use of tenecteplase in a patient with undifferentiated cardiac arrest with a return of spontaneous circulation after 1 hour of resuscitation, where basic life support was commenced immediately by a bystanding family member. Factors associated with an increased chance of survival from out-of-hospital cardiac arrest are discussed as well as the role of thrombolytics in cardiopulmonary resuscitation.
authors.affiliation: Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, 8036 Graz, Austria. sylvia.archan@meduni-graz.at
authors.forename: Sylvia
authors.initials: S
authors.lastname: Archan
authors.forename: Gerhard
authors.initials: G
authors.lastname: Prause
authors.forename: Bernhard
authors.initials: B
authors.lastname: Kügler
authors.forename: Rainer
authors.initials: R
authors.lastname: Gumpert
authors.forename: Giorgio
authors.initials: G
authors.lastname: Giacomini
mesh_terms: D000789:Angina, Unstable / Q000150:complications / Q000601:surgery; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D001026:Coronary Artery Bypass; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006323:Heart Arrest / Q000150:complications / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000150:complications / Q000628:therapy; D000077785:Tenecteplase; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator; D000077785:Tenecteplase