title: Bacteremia caused by VanC-type enterococci in a university hospital in Japan: a 6-year survey.
abstract: We retrospectively examined the clinical and microbiological characteristics of bacteremia caused by intrinsically vancomycin-resistant (VanC-type) enterococci in a university hospital in Japan. Five cases of Enterococcus gallinarum and four of Enterococcus casseliflavus bacteremia were identified during the 6 years of the survey. Of the nine cases, five were related to neutropenic states with hematologic diseases and four were related to biliary tract infection with hepatobiliary or pancreatic diseases. VanC-type enterococci were associated with 12% of all the enterococcal bacteremias, indicating that these species cause bacteremia more frequently in Japan than in previously reported areas.
authors.affiliation: Department of Infectious Diseases, Tsukuba University Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan. hkogane@mail.hosp.tsukuba.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koganemaru
authors.forename: Shigemi
authors.initials: S
authors.lastname: Hitomi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D001426:Bacterial Proteins / Q000235:genetics*; D016983:Enterococcus / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology / Q000382:microbiology; D006306:Health Surveys; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010453:Peptide Synthases / Q000235:genetics*; D014640:Vancomycin / Q000494:pharmacology; D020713:Vancomycin Resistance / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D014640:Vancomycin; D010453:Peptide Synthases; C108395:VanC protein, Enterococcus