[In vivo effects of Qizheng-xiaotong plaster on soft tissue injury of rabbit ears].
OBJECTIVE
To explore in vivo effects of Qizheng-xiaotong plaster on soft tissue injury in rabbit ears at different periods and to offer theoretical bases for clinical application.


METHODS
The experimental models of soft tissue injury in ears were produced in 10 New Zealand white rabbits, and the ears were divided into three groups at the 1st, 2nd, 3rd week. The normal group and treatment group were given the Qizheng-xiaotong plaster extract, and the model group with normal saline. Microscopic analysis, digital collection system, infrared temperature tester and thickness tester were applied to determine the changes of soft tissue injury in local microcirculation and the temperature change after 0, 0.5, 3 and 5 hours, and swelling change at 1 to 5 days respectively.


RESULTS
At the 3rd hour, blood velocity speeded up in normal group and model group, and it lasted for two hours in model group. As compared with model group, it slowed down to original level in treatment group at the 5th hour and the soft tissue swelling decreased from the 3rd to the 5th day as well.


CONCLUSIONS
The application of Qizheng-xiaotong plaster is effective in preventing further soft tissue oedema and haematoma. It can make the soft tissue swelling decreased at chronic stage compared with that at acute stage.
Wang
Yong-Zhi
YZ
Institute of Orthopedic and Traumatology, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Dong
Fu-Hui
FH
Zhong
Hong-Gang
HG
Zhang
Wan-Qiang
WQ
D000818:Animals; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004431:Ear, External / Q000187:drug effects / Q000293:injuries* / Q000503:physiopathology; D006801:Humans; D008833:Microcirculation / Q000187:drug effects; D011817:Rabbits; D017695:Soft Tissue Injuries / Q000188:drug therapy* / Q000503:physiopathology
D004365:Drugs, Chinese Herbal