The association between previous statin use and development of atrial fibrillation in patients presenting with acute coronary syndrome.
OBJECTIVE
To examine the association between statin use and the development of atrial fibrillation (AF) in patients presenting with acute coronary syndrome (ACS).


METHODS
From a total of 1000 patients presenting with ACS 241 were on and 759 were not on statin. An AF episode was accepted as endpoint.


RESULTS
The incidence of AF was less frequent in statin group compared to non-statin group (5% vs 10%, respectively, p=0.01). Independent predictors of AF were left atrial diameter, use of statin, age, hypertension, previous AF and use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers.


CONCLUSIONS
In ACS patients, statin treatment was associated with lower incidence of AF.
Ozaydin
Mehmet
M
Department of Cardiology, School of Medicine, Suleyman Demirel University, Isparta, Turkey. mehmetozaydin@hotmail.com
Turker
Yasin
Y
Erdogan
Dogan
D
Karabacak
Mustafa
M
Dogan
Abdullah
A
Varol
Ercan
E
Gonul
Emel
E
Altinbas
Ahmet
A
D054058:Acute Coronary Syndrome / Q000453:epidemiology*; D000367:Age Factors; D000368:Aged; D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000453:epidemiology*; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging; D006333:Heart Failure / Q000453:epidemiology; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume; D014463:Ultrasonography
D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors