title: Anti-Candida activity of alpha-melanocyte-stimulating hormone (alpha-MSH) peptides.
abstract: Previously, alpha-MSH, a 13-amino acid neuropeptide and the tripeptide alpha-MSH have been shown to possess potent antimicrobial properties. We performed microplate based growth inhibition assays on C. albicans with alpha-MSH, but could not observe any growth inhibiting effect. Repeating the originally published assay with different C. albicans strains, we detected a mild growth inhibiting effect of 100 microM alpha-MSH, but again no effect of alpha-MSH.
authors.forename: Isabella
authors.initials: I
authors.lastname: Rauch
authors.forename: Simone
authors.initials: S
authors.lastname: Holzmeister
authors.forename: Barbara
authors.initials: B
authors.lastname: Kofler
mesh_terms: D002176:Candida albicans / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D000521:alpha-MSH / Q000494:pharmacology*
chemical_list: D000521:alpha-MSH