Primary cutaneous diffuse large B-cell lymphoma (leg type) after renal allograft: case report and review of the literature.
We report a case of a 58-year-old man who presented with a rapidly growing proliferative lesion on the left lower limb, clinically resembling a soft tissue sarcoma 3 years after renal allograft. There was no evidence of systemic involvement on bone marrow needle aspiration and computed tomography (CT) scans of the chest and abdomen. The lesion turned out to be primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT), as defined in the recent World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification of cutaneous lymphomas by skin biopsy. Immunosuppression reduction, chemotherapy with CHOP regimen and local radiotherapy induced complete remission of the tumor.
Zhao
Jing
J
Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
Han
Bing
B
Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China. hanbing_li@sina.com.
Shen
Ti
T
Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
Zhao
Yongqiang
Y
Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
Wang
Tao
T
Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
Liu
Yuehua
Y
Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
Fang
Kai
K
Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
Zhong
Dingrong
D
Department of Pathology, Peking Union Medical College Hospital, 100730, Beijing, China.
Ling
Qing
Q
Department of Pathology, Peking Union Medical College Hospital, 100730, Beijing, China.
D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D007866:Leg / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012074:Remission Induction / Q000379:methods; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology