title: [Correlation between magnetic resonance imaging findings and proliferating cell nuclear antigen expression in peripheral lung cancer].
abstract: OBJECTIVE
  To study the correlation between magnetic resonance imaging (MRI) findings and proliferating cell nuclear antigen (PCNA) expression in peripheral lung cancer.
  
  
  METHODS
  The expression of PCNA was detected by means of SABC immunohistochemistry in 45 cases of surgically and pathologically confirmed peripheral lung cancer. The correlation between PCNA expression in the tumors and the MRI findings was analyzed.
  
  
  RESULTS
  PCNA expression was correlated to the differentiation, tumor size, lobulation, and mediastinal lymph node metastasis of the tumors (P<0.05), but not to the histological type, clinical stage, pleural retraction, spiculation, or signal feature.
  
  
  CONCLUSIONS
  Correlations are found between MRI findings of lung cancer and abnormal expression of PCNA.
authors.affiliation: Department of CT/MR, Panyu People's Hospital, Guangzhou 511400, China. xzmgz@126.com
authors.forename: Zhi-ming
authors.initials: ZM
authors.lastname: Xiang
authors.forename: Yu-sheng
authors.initials: YS
authors.lastname: Hu
authors.forename: Shi-yu
authors.initials: SY
authors.lastname: Zhao
authors.forename: Li-lian
authors.initials: LL
authors.lastname: Tan
authors.forename: Zhi-hua
authors.initials: ZH
authors.lastname: Li
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism*
chemical_list: D018809:Proliferating Cell Nuclear Antigen