title: Hybrid microgels with antibacterial properties.
abstract: In the present work, we have used aqueous microgels as containers for the deposition of silver nanoparticles (AgNPs). It has been shown that AgNPs can be effectively incorporated in the microgel interior during the in situ reduction of silver ions. Obtained hybrid microgels with variable AgNPs loading (from 1 to 12 wt.-%) have been used as antibacterial agents for two bacteria types. The experimental results indicate that porous microgel structure allows the release of the silver ions from the AgNPs surface into an aqueous phase. This ensures effective reduction in the number of bacterial colonies in test plates and complete bacteria killing. The antibacterial efficiency of the microgel particles increases with AgNPs loading.
authors.affiliation: Department of Macromolecular Chemistry and Textile Chemistry, Technische Universität Dresden, Dresden, Germany.
authors.forename: Nadine
authors.initials: N
authors.lastname: Häntzschel
authors.forename: Rolf-Dieter
authors.initials: RD
authors.lastname: Hund
authors.forename: Heike
authors.initials: H
authors.lastname: Hund
authors.forename: Marc
authors.initials: M
authors.lastname: Schrinner
authors.forename: Christian
authors.initials: C
authors.lastname: Lück
authors.forename: Andrij
authors.initials: A
authors.lastname: Pich
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001672:Biocompatible Materials / Q000737:chemistry; D002209:Caprolactam / Q000737:chemistry; D015169:Colony Count, Microbial; D004852:Epoxy Compounds / Q000737:chemistry; D005782:Gels / Q000737:chemistry* / Q000494:pharmacology; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012834:Silver / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D004852:Epoxy Compounds; D005782:Gels; D008689:Methacrylates; D014753:Vinyl Compounds; D012834:Silver; D002209:Caprolactam; C007870:glycidyl methacrylate