[Incidence, prevalence and risk factors for a first infectious complication on a totally implantable venous-access port].
BACKGROUND
Totally implantable venous-access ports (TIVAP) should present less risk of complications than central venous catheters over a long time period.


OBJECTIVE
Firstly, the study's objective was to assess the prevalence and incidence of a first infectious complication on a TIVAP and secondly, to assess the risk factors associated with this first infection.


METHODS
The authors made a longitudinal historical cohort study of patients with a TIVAP in 2003, in the Dijon University Hospital.


RESULTS
Two hundred and nineteen patients (sex-ratio 1.9) were included, with a total follow-up of 92,773 patients-days. Ninety percent of the TIVAP were used for chemotherapy, 5% for antibiotic drug administration, 2% for parenteral nutrition and 3% for other reasons (recurrent blood transfusions, etc.). Overall, 34 (16.3%) out of 209patients presented with at least one infectious complication, with an incidence rate of 0.37infection/1,000patients-days. The 5-year cumulative probability to be free of infectious complication was only 62.8%. In multivariate analysis, only underlying hematological neoplasia (by contrast with solid tumors) was significantly associated to a higher risk of infectious complication.


CONCLUSIONS
The infectious risk linked to the use of TIVAP is significant, higher in case of underlying hematological neoplasia and during the first months of use.
Crisinel
M
M
Département d'infectiologie, CHU de Dijon, France.
Mahy
S
S
Ortega-Debalon
P
P
Buisson
M
M
Favre
J-P
JP
Chavanet
P
P
Piroth
L
L
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D055499:Catheter-Related Infections / Q000453:epidemiology* / Q000209:etiology*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D055815:Young Adult