Zoonotic vaccinia virus: clinical and immunological characteristics in a naturally infected patient.
Vaccinia virus was used as vaccine to eradicate smallpox. We report a zoonotic case of vaccinia virus infection in a 30-year-old patient who became infected after handling sick dairy cattle. The patient had inflamed lesions and systemic symptoms. Laboratory findings were indicative of down-modulated immune responses to the virus.
Trindade
Giliane S
GS
Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Guedes
Maria I C
MI
Drumond
Betânia P
BP
Mota
Bruno E F
BE
Abrahão
Jônatas S
JS
Lobato
Zélia I P
ZI
Gomes
Juliana A S
JA
Corrêa-Oliveira
Rodrigo
R
Nogueira
Maurício L
ML
Kroon
Erna G
EG
da Fonseca
Flávio G
FG
D000328:Adult; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission* / Q000821:virology*; D002478:Cells, Cultured; D006801:Humans; D007371:Interferon-gamma / Q000378:metabolism; D007963:Leukocytes, Mononuclear / Q000276:immunology; D008297:Male; D012867:Skin / Q000473:pathology; D014615:Vaccinia / Q000175:diagnosis* / Q000276:immunology / Q000662:veterinary*; D014616:Vaccinia virus / Q000276:immunology / Q000302:isolation & purification*; D015047:Zoonoses / Q000635:transmission* / Q000821:virology*
D007371:Interferon-gamma