title: Inhibin A levels and severity of preeclampsia.
abstract: OBJECTIVE
  To evaluate the use of third trimester inhibin A levels to assess the severity of preeclampsia.
  
  
  METHODS
  Blood samples were taken from women diagnosed with mild and severe preeclampsia during the third trimester of pregnancy. Blood samples were collected in plain tubes, centrifuged and stored at -80 degrees C until analyzed. All serum samples were measured for inhibin A levels by enzyme-linked immunosorbent assays.
  
  
  RESULTS
  Inhibin A levels were greater in the severe (1,435.9 +/- 603.2 pg/mL) than in the mild preeclampsia group (1,021.9 +/- 438.8 pg/mL, P = 0.014).
  
  
  CONCLUSIONS
  Inhibin A levels rise with increasing severity of disease. However, there is considerable overlap of serum inhibin A levels in women with mild and severe preeclampsia. Inhibin A is therefore not a useful adjunct for the classification of preeclampsia.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, Thailand. vorapong.p@chula.ac.th
authors.forename: Vorapong
authors.initials: V
authors.lastname: Phupong
authors.forename: Krissada
authors.initials: K
authors.lastname: Paiwattananupant
authors.forename: Sittisak
authors.initials: S
authors.lastname: Honsawek
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007265:Inhibins / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D055815:Young Adult
chemical_list: C422362:inhibin A; D007265:Inhibins