title: Antimicrobial resistance and prevalence of canine uropathogens at the Western College of Veterinary Medicine Veterinary Teaching Hospital, 2002-2007.
abstract: Between January 2002 and June 2007, uropathogens were isolated from 473 of 1557 canine urine samples submitted to Prairie Diagnostic Services from the Western College of Veterinary Medicine Veterinary Teaching Hospital. Culture and susceptibility results were analyzed, retrospectively, to estimate the prevalence of common bacterial uropathogens in dogs with urinary tract infections and to identify changes in antimicrobial resistance. The most common pathogens identified were Escherichia coli, Staphylococcus intermedius, Enterococcus spp., and Proteus spp. Antimicrobial resistance increased during the study period, particularly among recurrent E. coli isolates. Using the formula to help select rational antimicrobial therapy (FRAT), bacterial isolates were most likely to be susceptible to gentamicin, fluoroquinolones, amoxicillin-clavulanic acid, and groups 4 and 5 (third generation) cephalosporins.
authors.affiliation: Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4. katherine.ball@usask.ca
authors.forename: Katherine R
authors.initials: KR
authors.lastname: Ball
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Rubin
authors.forename: M
authors.initials: M
authors.lastname: Chirino-Trejo
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Dowling
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D002170:Canada / Q000453:epidemiology; D015169:Colony Count, Microbial / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D016983:Enterococcus / Q000187:drug effects / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D005260:Female; D008297:Male; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D015995:Prevalence; D011511:Proteus / Q000187:drug effects / Q000254:growth & development; D012189:Retrospective Studies; D013210:Staphylococcus / Q000187:drug effects / Q000254:growth & development; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D014556:Urine / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents