title: [A case of metastases of umbilicus (Sister Mary Joseph's nodule)].
abstract: We report a case of advanced unresectable pancreatic cancer (cT4N1M0/stage IVa). The patient was a 68-year-old man. Chemo-radiation therapy (CRT) with GEM (1,000 mg/body) was administered once a week on days 1, 8 and 15 for 3 weeks. The radiotherapy dose was 45 Gy (1.5 Gy x 2/day, 15 days). After CRT, the patient was treated with a GEM+ UFT-E combination chemotherapy. When that was done, CT scan revealed metastases of umbilicus (Sister Mary Joseph's nodule) and the liver. Microwave Coagulation Therapy for the liver metastasis and tumorectomy for metastasis of umbilicus were performed. But he died after 4 months from the therapies.
authors.affiliation: Dept. of Surgery, Nishinomiya Municipal Central Hospital.
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamashita
authors.forename: Masato
authors.initials: M
authors.lastname: Sakon
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Hiura
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Nakano
authors.forename: Naozumi
authors.initials: N
authors.lastname: Higaki
authors.forename: Masakazu
authors.initials: M
authors.lastname: Murakami
authors.forename: Hirohito
authors.initials: H
authors.lastname: Hayashida
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Kan
authors.forename: Takao
authors.initials: T
authors.lastname: Ichihara
mesh_terms: D000008:Abdominal Neoplasms / Q000097:blood / Q000556:secondary* / Q000628:therapy; D000368:Aged; D000951:Antigens, Neoplasm / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D010190:Pancreatic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure; D014472:Umbilicus / Q000473:pathology*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; C042317:DU-PAN-2 antigen, human