[Mechanisms of the therapeutic effect of immunoglobulins in the treatment of bronchial asthma].
Data on the therapeutic effectiveness of intravenous injections of immunoglobulins in high doses in patients with bronchial asthma are analyzed. Some possible mechanisms of this therapeutic effect are considered, which are related to of immunoglobulin fragments capable of interacting with cytochrome P-450 and NO-synthase systems of the liver.
Kovalev
I E
IE
Kovaleva
V L
VL
Rumiantseva
E I
EI
D001249:Asthma / Q000188:drug therapy* / Q000201:enzymology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use*; D008099:Liver / Q000201:enzymology*; D019001:Nitric Oxide Synthase / Q000378:metabolism*
D007136:Immunoglobulins; D003577:Cytochrome P-450 Enzyme System; D019001:Nitric Oxide Synthase