title: Bioactivities of polyphenolics from the roots of Bauhinia racemosa.
abstract: Various extracts of Bauhinia racemosa Lamk. (roots) and the isolated polyphenolics, viz. 1,7,8,12b-tetrahydro-2,2,4-trimethyl-10-methoxy-2H-benzo [6,7] cyclohepta[1,2,3-de][1]benzopyran-5,9-diol (racemosol) (1), 1,7,8,12b-tetrahydro-2,2,4-trimethyl-2H-benzo[6,7]cyclohepta[1,2,3-de][1]benzopyran-5,10,11-triol (2), and 1,7,8,12b-tetrahydro-2,2,4-trimethyl-2H-benzo[6,7] cyclohepta [1,2,3-de][1]benzopyran-5,9,10-triol (de-O-methyl racemosol) (3) were screened for antibacterial, antifungal, and antiviral activities. The isolated compounds exhibited profound antibacterial and antifungal activities while methanol extract exhibited potential efficacy against Herpes simplex virus.
authors.affiliation: Department of Chemistry, University of Rajasthan, Jaipur, 302 004, India. jainr_15@yahoo.co.in
authors.forename: Renuka
authors.initials: R
authors.lastname: Jain
authors.forename: Umesh
authors.initials: U
authors.lastname: Saxena
authors.forename: Kiran
authors.initials: K
authors.lastname: Rathore
authors.forename: Satish C
authors.initials: SC
authors.lastname: Jain
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D036481:Bauhinia / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D059808:Polyphenols
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D005419:Flavonoids; D007202:Indicators and Reagents; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols