Expression of orexin A and its receptor 1 in the vestibular glands of the cattle genital tract.
The hypothalamic peptide orexin A (oxA) binds specifically the G-protein-coupled orexin receptor 1 (ox1R). It is involved in many physiological functions including the regulation of food intake, sleep-wake cycle, arterial blood pressure, heart rate, and sexual behavior. The localization of oxA in adrenal glands, stomach, bowel, pancreas, and testis has recently been assessed. Here, we provide the first evidence for the expression of oxA and ox1R in the vestibular glands of mammalian genital tract.
Pavone
Luigi Michele
LM
Department of Biological Structures, Functions and Technologies, University of Naples Federico II, Via F. Delpino n. 1, Naples, Italy.
Tafuri
Simona
S
Avallone
Luigi
L
Staiano
Norma
N
Vittoria
Alfredo
A
D000818:Animals; D001483:Base Sequence; D015153:Blotting, Western; D002417:Cattle; D017931:DNA Primers / Q000235:genetics; D005260:Female; D005836:Genitalia, Female / Q000033:anatomy & histology / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism*; D055099:Neuroendocrine Cells / Q000378:metabolism; D009479:Neuropeptides / Q000235:genetics / Q000378:metabolism*; D064446:Orexin Receptors; D000068797:Orexins; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled / Q000235:genetics / Q000378:metabolism*; D018013:Receptors, Neuropeptide / Q000235:genetics / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014018:Tissue Distribution
D017931:DNA Primers; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D064446:Orexin Receptors; D000068797:Orexins; D012333:RNA, Messenger; D043562:Receptors, G-Protein-Coupled; D018013:Receptors, Neuropeptide