title: Targeted nanomedicines: effective treatment modalities for cancer, AIDS and brain disorders.
abstract: Novel technology in the nanomedicine field is expected to develop innovative products as targeted drug-delivery approaches. Targeted drug delivery of various drugs for the treatment of cancer, AIDS and brain disorders is the primary research area in which nanomedicines have a major role and need. This review is concerned with emerging targeted nanomedicines (polymeric nanoparticles, solid lipid nanoparticles, polymeric micelles, dendrimers, liposomes, gold nanoparticles and magnetic nanoparticles) and multifunctional carriers capable of combining targeted drug delivery and imaging (polymeric micelles, dendrimers and magnetic nanoparticles) in the field of pharmaceutical applications. The significant toxicity issues associated with these nanomedicines are also explored here.
authors.affiliation: Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Madaswamy S
authors.initials: MS
authors.lastname: Muthu
authors.forename: Sanjay
authors.initials: S
authors.lastname: Singh
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy*; D001927:Brain Diseases / Q000628:therapy*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D050997:Nanomedicine / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use* / Q000633:toxicity; D009369:Neoplasms / Q000628:therapy*