[Glutathione and male reproduction].
Reduced glutathione (GSH) , the most abundant non-protein thiol in mammalian cells, exists extensively in the human body and plays a key role in many biological processes, including the synthesis of proteins and DNA and the transport of amino acids, especially in protecting cells against oxidation. GSH also shows its important clinical value in the treatment of many diseases. It has been reported that GSH also widely exists in the male reproductive system and has a therapeutic role in male infertility. The objective of this review is to summarize the distribution of GSH in the male reproductive system and its therapeutic value for male infertility.
Hou
Bao-Shan
BS
Department of Andrology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.
Wang
Zong-Dan
ZD
Shang
Xu-Jun
XJ
D005837:Genitalia, Male / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism* / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D027724:Reproductive Techniques, Assisted
D005978:Glutathione