Pulmonary veno-occlusive disease in myeloproliferative disorder.
The present study reports a case of biopsy-proven pulmonary veno-occlusive disease as a cause of severe pulmonary hypertension in a patient suffering from a chronic myeloproliferative disorder. The pulmonary disease evolved favourably under treatment with defibrotide, a pro-fibrinolytic medication used in hepatic veno-occlusive disease.
Willems
E
E
Department of Medicine, Division of Haematology, University Hospital Centre, University of Liege, Domaine Universitaire du Sart-Tilman, Liege, Belgium.
Canivet
J-L
JL
Ghaye
B
B
de Leval
L
L
Radermecker
M
M
Preiser
J-C
JC
Beguin
Y
Y
D000368:Aged; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D009196:Myeloproliferative Disorders / Q000150:complications* / Q000473:pathology; D011089:Polydeoxyribonucleotides / Q000627:therapeutic use; D011668:Pulmonary Veno-Occlusive Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*
D005343:Fibrinolytic Agents; D011089:Polydeoxyribonucleotides; C036901:defibrotide