title: [Psychological stress status in patients with acute coronary syndrome and stable angina pectoris].
abstract: OBJECTIVE
  To observe the psychological stress status in patients with acute coronary syndrome (ACS) and stable angina pectoris (SA).
  
  
  METHODS
  The intensity of social psychological stress and the serum levels of IL-6, CRP and ICAM-1 were determined in patients with ACS (n = 67) and SA (n = 33).
  
  
  RESULTS
  (1) The percentage of patients with psychological stress was significantly higher in ACS than that in SA group (78.8% vs. 21.2%, P < 0.01). (2) The serum levels of CRP [(14.82 +/- 5.07) g/L vs. (8.78 +/- 4.34) g/L], IL-6 [(101.7 +/- 22.2) ng/L vs. (71.1 +/- 23.5) ng/L] and sICAM-1 [(1.41 +/- 0.47) mg/L vs. (0.82 +/- 0.37) mg/L] were significantly higher in psychological stress group than those in non-psychological stress group (all P < 0.05). Serum CRP [(18.91 +/- 3.12) g/L vs. (6.20 +/- 2.46) g/L], IL-6 [(114.6 +/- 15.2) ng/L vs. (56.4 +/- 15.8) ng/L] and sICAM-1 [(1.67 +/- 0.39) mg/L vs. (0.63 +/- 0.28) mg/L] levels in ACS group were significantly higher than those in SA group (all P < 0.01).
  
  
  CONCLUSIONS
  Higher psychological stress was associated with higher risk of ACS and increased serum inflammatory cytokines.
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou 450003, China. limuwei @medmail.com.cn
authors.forename: Mu-Wei
authors.initials: MW
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Chuan-Yu
authors.initials: CY
authors.lastname: Gao
authors.forename: Yu-Xiang
authors.initials: YX
authors.lastname: Shen
authors.forename: Ye-Xin
authors.initials: YX
authors.lastname: Ma
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000523:psychology*; D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D013315:Stress, Psychological
chemical_list: D015850:Interleukin-6; D018799:Intercellular Adhesion Molecule-1; D002097:C-Reactive Protein