title: Pulmonary veno-occlusive disease in myeloproliferative disorder.
abstract: The present study reports a case of biopsy-proven pulmonary veno-occlusive disease as a cause of severe pulmonary hypertension in a patient suffering from a chronic myeloproliferative disorder. The pulmonary disease evolved favourably under treatment with defibrotide, a pro-fibrinolytic medication used in hepatic veno-occlusive disease.
authors.affiliation: Department of Medicine, Division of Haematology, University Hospital Centre, University of Liege, Domaine Universitaire du Sart-Tilman, Liege, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Willems
authors.forename: J-L
authors.initials: JL
authors.lastname: Canivet
authors.forename: B
authors.initials: B
authors.lastname: Ghaye
authors.forename: L
authors.initials: L
authors.lastname: de Leval
authors.forename: M
authors.initials: M
authors.lastname: Radermecker
authors.forename: J-C
authors.initials: JC
authors.lastname: Preiser
authors.forename: Y
authors.initials: Y
authors.lastname: Beguin
mesh_terms: D000368:Aged; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D009196:Myeloproliferative Disorders / Q000150:complications* / Q000473:pathology; D011089:Polydeoxyribonucleotides / Q000627:therapeutic use; D011668:Pulmonary Veno-Occlusive Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*
chemical_list: D005343:Fibrinolytic Agents; D011089:Polydeoxyribonucleotides; C036901:defibrotide