Infertility and bilateral adrenal tumors.
An infertile man who presents with azoospermia and bilateral adrenal tumors reveals an XX karyotype and congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hysterectomy and bilateral oophorectomy performed in infancy and lack of treatment resulted in full masculinization.
Ishay
Avraham
A
Endocrine Institute, Haemek Medical Center, Afula, Israel. ishayav@netvision.net.il
Luboshitzky
Rafael
R
D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D053713:Azoospermia / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D008297:Male; D011859:Radiography