title: [Evaluation of percutaneous vertebroplasty of 190 cases].
abstract: OBJECTIVE
  To evaluate the therapeutic effect of percutaneous vertebroplasty (PVP) guided by X-ray fluoroscopy in treating osteoporotic spinal compression fractures, hemangioma of vertebra and metastatic carcinoma of vertebra.
  
  
  METHODS
  One hundred and ninety patients with 275 diseased vertebra underwent PVP under the guidance of C-arm fluoroscopy (male 80, female 110, ranging in age from 53 to 91 years, with an average of 66 years). Bone marrow biopsy needle was inserted percutaneously via transpedicular way into the diseased vertebra. Polymethylmethacrylate (PMMA) was then injected into the diseased vertebra. Visual analogue scale (VAS), mobility and analgesic usage were evaluated pre-operation and 3 months after PVP.
  
  
  RESULTS
  PVP was successful in 190 cases (275 vertebrae). VAS was tested by t test at 3 months after PVP (P < 0.05). Simultaneously, scale of patient's mobility and scale of analgesic usage was tested by rank sum test at 3 months after PVP (P < 0.05).
  
  
  CONCLUSIONS
  As the mimimally invasive operation, PVP can alleviate pain in early time, avoid kinds of complications by shortening the patient's time in bed and have the characteristic of simply operative procedure and low expenses. It is an effective mini-invasive technique for osteoporotic spinal compression fractures, hemangioma of vertebra and metastatic carcinoma of vertebra.
authors.affiliation: Luoyang Traditional Chinese Orthopaedic and Traumatology Hospital of Henan, Luoyang 471002, Henan, China. Lyzgzg@yahoo.com.cn
authors.forename: Gang
authors.initials: G
authors.lastname: Zhao
authors.forename: Xiang-Qin
authors.initials: XQ
authors.lastname: Shi
authors.forename: Huai-Liang
authors.initials: HL
authors.lastname: Zheng
authors.forename: Hong-Xun
authors.initials: HX
authors.lastname: Cui
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Zhou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005471:Fluoroscopy; D050815:Fractures, Compression / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications*; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications / Q000517:prevention & control; D016103:Spinal Fractures / Q000601:surgery*; D013125:Spinal Neoplasms / Q000601:surgery*; D054854:Vertebroplasty / Q000009:adverse effects / Q000379:methods*
chemical_list: D019904:Polymethyl Methacrylate