Use of intradermal botulinum toxin to reduce sebum production and facial pore size.
OBJECTIVE
Review the safety profile and subjective efficacy of intradermal botulinum toxin type A in facial pore size and sebum production.


METHODS
Retrospective analysis of 20 patients.


RESULTS
Twenty consecutive patients with a single application of intradermal botulinum toxin type A were examined: Patients (17/20) noted an improvement in sebum production and a decrease in pores size at 1 month after injection. No complications were observed, and 17/20 patients were satisfied with the procedure.


CONCLUSIONS
Preliminary data suggests that intradermal botulinum toxin may play a role in decreasing sebum production. Further quantitive study may be necessary to determine effects of intradermal botulinum toxin on pore size.
Shah
Anil R
AR
Division of Facial Plastic Surgery, Department of Otolaryngology, University of Chicago, IL, USA. shah@shahfacialplastics.com
D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000494:pharmacology*; D005145:Face; D005500:Follow-Up Studies; D006801:Humans; D007271:Injections, Intradermal; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000494:pharmacology*; D016062:Porosity; D012189:Retrospective Studies; D012629:Sebum / Q000187:drug effects*; D012867:Skin / Q000033:anatomy & histology / Q000187:drug effects* / Q000378:metabolism
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A