[Effects of phytoecdysteroids and bemithyl on functional, metabolic, and immunobiological parameters of working capacity in experimental animals].
Influence of phytoecdysteroids (isolated from Ajuga turkestanica) and bemithyl on the duration of swimming of laboratory animals (mice, rats) under various experimental conditions was studied. Turkesteron and cyasteron increased duration of dynamic work carried out by animals, decreased fatigue, and accelerated recovery processes to a greater extent that did bemithyl. The positive influence of phytoecdysteroids on the working capacity is based on the activation of metabolic processes in skeletal muscles, directed to support the homeostasis of energy production. Phytoecdysteroids also accelerate recovery of immune reactions which are decreased due to the exhausting physical work.
Syrov
V N
VN
Shakhmurova
G A
GA
Khushbaktova
Z A
ZA
D031328:Ajuga / Q000737:chemistry; D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D026461:Ecdysteroids / Q000737:chemistry / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D005221:Fatigue / Q000378:metabolism; D008297:Male; D051379:Mice; D018482:Muscle, Skeletal / Q000378:metabolism; D051381:Rats; D013265:Stigmasterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D013550:Swimming / Q000502:physiology*
D001562:Benzimidazoles; D026461:Ecdysteroids; C002082:cyasterone; C049825:bemethyl; D013265:Stigmasterol