title: Enantioselective intermolecular crossed-conjugate additions between nitroalkenes and alpha,beta-enals through a dual activation strategy.
abstract: Double the fun: The title reaction was developed by using a Lewis base/iminium activation strategy (see scheme). The reaction proceeded with excellent yields and ee values, and the products were additionally transformed into a single enantiomer of a substituted pyrrolidine with excellent retention of configuration.
authors.affiliation: C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, USA.
authors.forename: Cheng
authors.initials: C
authors.lastname: Zhong
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Chen
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Petersen
authors.forename: Novruz G
authors.initials: NG
authors.lastname: Akhmedov
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi