title: Spontaneous resolution of cystic hygroma and hydrops in a fetus with Noonan's syndrome.
abstract: Many studies have shown that the prognosis of cystic hygroma associated with hydrops fetalis is poor. We report a rare case of fetal cystic hygroma and hydrops fetalis that spontaneously resolved with subsequent delivery at 37 weeks of a living female infant with Noonan's syndrome. The prognostic significance of prenatal resolution of cystic hygroma and hydrops is uncertain. Serial evaluation of affected fetuses with ultrasound imaging may help clarify pathogenesis of cystic hygroma with associated hydrops, as well as mechanisms underlying spontaneous resolution.
authors.affiliation: Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Asuka
authors.initials: A
authors.lastname: Kiyota
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Tsukimori
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yumoto
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hojo
authors.forename: Seiichi
authors.initials: S
authors.lastname: Morokuma
authors.forename: Kotaro
authors.initials: K
authors.lastname: Fukushima
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takahata
authors.forename: Hideki
authors.initials: H
authors.lastname: Nakayama
authors.forename: Norio
authors.initials: N
authors.lastname: Wake
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging*; D007231:Infant, Newborn; D018191:Lymphangioma, Cystic / Q000150:complications / Q000000981:diagnostic imaging*; D009634:Noonan Syndrome / Q000150:complications* / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011379:Prognosis; D012075:Remission, Spontaneous; D016216:Ultrasonography, Prenatal