Replication forks, chromatin loops and dormant replication origins.
When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.
Blow
J Julian
JJ
Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. j.j.blow@dundee.ac.uk
Ge
Xin Quan
XQ
D000818:Animals; D002453:Cell Cycle; D002843:Chromatin; D004261:DNA Replication; D005057:Eukaryotic Cells / Q000166:cytology; D018741:Replication Origin
D002843:Chromatin