title: WHO 1st consultation on the development of a global biodosimetry laboratories network for radiation emergencies (BioDoseNet).
abstract: The World Health Organization (WHO) held a consultation meeting at WHO Headquarters, Geneva, Switzerland, December 17-18, 2007, to develop the framework for a global biodosimetry network. The WHO network is envisioned to enable dose assessment using multiple methods [cytogenetics, electron paramagnetic resonance (EPR), radionuclide bioassays, etc.]; however, the initial discussion focused on the cytogenetic bioassay (i.e., metaphase-spread dicentric assay). Few regional cytogenetic biodosimetry networks have been established so far. The roles and resources available from United Nations (UN) agencies that provide international cooperation in biological dosimetry after radiological emergencies were reviewed. In addition, extensive reliance on the use of the relevant International Standards Organization (ISO) standards was emphasized. The results of a WHO survey of global cytogenetic biological dosimetry capability were reported, and while the survey indicates robust global capability, there was also a clear lack of global leadership and coordination. The expert group, which had a concentrated focus on cytogenetic biodosimetry, formulated the general scope and concept of operations for the development of a WHO global biodosimetry laboratory network for radiation emergencies (BioDoseNet). Follow-on meetings are planned to further develop technical details for this network.
authors.affiliation: Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, MD, USA.
authors.forename: William F
authors.initials: WF
authors.lastname: Blakely
authors.forename: Zhanat
authors.initials: Z
authors.lastname: Carr
authors.forename: May Chin-May
authors.initials: MC
authors.lastname: Chu
authors.forename: Renu
authors.initials: R
authors.lastname: Dayal-Drager
authors.forename: Kenzo
authors.initials: K
authors.lastname: Fujimoto
authors.forename: Michael
authors.initials: M
authors.lastname: Hopmeir
authors.forename: Ulrike
authors.initials: U
authors.lastname: Kulka
authors.forename: Patricia
authors.initials: P
authors.lastname: Lillis-Hearne
authors.forename: Gordon K
authors.initials: GK
authors.lastname: Livingston
authors.forename: David C
authors.initials: DC
authors.lastname: Lloyd
authors.forename: Natalie
authors.initials: N
authors.lastname: Maznyk
authors.forename: Maria Del Rosario
authors.initials: Mdel R
authors.lastname: Perez
authors.forename: Horst
authors.initials: H
authors.lastname: Romm
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Takashima
authors.forename: Phillipe
authors.initials: P
authors.lastname: Voisin
authors.forename: Ruth C
authors.initials: RC
authors.lastname: Wilkins
authors.forename: Mitsuaki A
authors.initials: MA
authors.lastname: Yoshida
mesh_terms: D003625:Data Collection; D006801:Humans; D038622:Internationality; D007753:Laboratories / Q000458:organization & administration* / Q000592:standards; D018579:Patient Selection; D010820:Physicians; D018788:Radioactive Hazard Release; D011874:Radiometry / Q000379:methods* / Q000592:standards; D012016:Reference Values; D013048:Specimen Handling; D014944:World Health Organization