title: Hemodialysis and nutritional status in children: malnutrition and cachexia.
abstract: Malnutrition is a common state in chronic hemodialyzed children. More than malnutrition, which infers that dietary supplementation would be curative, cachexia, which implies loss of protein stores, are combined factors of impaired linear growth and reduced muscle mass in uremic patients. Adequate diet to prevent malnutrition is of major importance. But to avoid cachexia in children on chronic hemodialysis, the management of acidosis, inflammation, abnormal metabolic rate, and endocrine disturbances should not, be forgotten. Daily hemodialysis regimen using convective flow therapy and ultrapure dialysate, i.e., on line hemodiafiltration together with growth hormone therapy, appears as a hopeful strategy for the chronic dialyzed child to achieve catch-up growth, a parameter of optimal nutrition.
authors.affiliation: Pédiatrie 1, CHU de Hautepierre, Strasbourg, France. Michel.Fischbach@chru-strasbourg.fr
authors.forename: Michel
authors.initials: M
authors.lastname: Fischbach
authors.forename: Céline
authors.initials: C
authors.lastname: Dheu
authors.forename: Laure
authors.initials: L
authors.lastname: Seuge
authors.forename: Nadia
authors.initials: N
authors.lastname: Orfanos
mesh_terms: D000293:Adolescent; D002100:Cachexia / Q000150:complications / Q000453:epidemiology / Q000209:etiology; D002648:Child; D015362:Child Nutrition Disorders / Q000453:epidemiology* / Q000209:etiology; D002675:Child, Preschool; D006130:Growth Disorders / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy; D009752:Nutritional Status; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D013006:Growth Hormone