A new HLA-B*35 allele, B*3589, detected in a Malaysian individual.
A novel human leukocyte antigen-B allele officially named B*3589, was found in an indigenous individual of Jehai ethnicity when sequencing was performed to investigate human genome variation in a research project. B*3589 differs form B*3505 in a point mutation at codon 169 (CGC to TGC) resulting in an amino acid change from Arg to Cys.
Phipps
M
M
School of Medicine and Health Sciences, Monash University (Sunway Campus), Kuala Lumpur, Malaysia. maudephipps@yahoo.co.uk
Jinam
T
T
D000483:Alleles; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D015235:HLA-B Antigens / Q000235:genetics*; D015797:HLA-B35 Antigen; D006801:Humans; D008296:Malaysia; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D015235:HLA-B Antigens; C540898:HLA-B*35:89 antigen; D015797:HLA-B35 Antigen