title: Influence of controlled vascular training on the pain free walking distance and plasmaviscosity in patients suffering from peripheral arterial occlusive disease.
abstract: Does controlled vascular training influence plasmaviscosity and the pain free walking distance in patients with peripheral arterial occlusive disease (paod) Fontaine stage II?37 patients, 24 men and 13 women with a mean age of 64.5 years SD 8.5 took part in ambulant vascular training over a period of 12 months.Before, after 6 months and after 12 months, pain free (pfwd) and maximum walking distance (mwd) was measured using a standardized treadmill program. Also ankle-brachials systolic pressure index (a-bspi), transcutaneous oxygen tension (tcPO2) and plasmaviscosity (pv) were measured.Pfwd increased from 212 SD 143 m to 371 SD 249 m (p<0.02). TcPO2 increased during training, but without statistically significance. A-bspi increased between the first 6 months of training statistically significant. Before training pv was 1.31 mPa s SD 0.10, after training period of 6 months it was 1.27 mPa s SD 0.11 (p=0.06) and 12 months later it was 1.28 SD 0.11 mPa s (p=0.35). The improvement of pfwd and the decrease of pv correlates (r=-0.39, p=0.05).In most patients, arterial vascular training improves pfwd and mwd. Simultaneously to the increase of the walking distances plasmaviscosity decreases and crurobrachial indexes increases. We found a coupling between improvement of pfwd and pv. Pv seems to participate in improvement of leg hemodynamics in patients with paod.
authors.affiliation: Department of Dermatology, University of Tübingen, 72076 Tübingen, Germany. Hans-Martin.Haefner@med.uni-tuebingen.de
authors.forename: Hans-Martin
authors.initials: HM
authors.lastname: Häfner
authors.forename: Irmgard
authors.initials: I
authors.lastname: Jünger
authors.forename: Annette
authors.initials: A
authors.lastname: Geyer
authors.forename: Michael
authors.initials: M
authors.lastname: Jünger
authors.forename: Anke
authors.initials: A
authors.lastname: Strölin
mesh_terms: D000368:Aged; D001809:Blood Viscosity; D005080:Exercise Test; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000534:rehabilitation*; D016491:Peripheral Vascular Diseases / Q000097:blood* / Q000534:rehabilitation*; D011446:Prospective Studies; D016138:Walking