title: Peptide-based Biopolymers in Biomedicine and Biotechnology.
abstract: Peptides are emerging as a new class of biomaterials due to their unique chemical, physical, and biological properties. The development of peptide-based biomaterials is driven by the convergence of protein engineering and macromolecular self-assembly. This review covers the basic principles, applications, and prospects of peptide-based biomaterials. We focus on both chemically synthesized and genetically encoded peptides, including poly-amino acids, elastin-like polypeptides, silk-like polymers and other biopolymers based on repetitive peptide motifs. Applications of these engineered biomolecules in protein purification, controlled drug delivery, tissue engineering, and biosurface engineering are discussed.
authors.affiliation: Department of Biomedical Engineering, Duke University, Box 90281, Durham, North Carolina 27708-0281.
authors.forename: Dominic
authors.initials: D
authors.lastname: Chow
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Nunalee
authors.forename: Dong Woo
authors.initials: DW
authors.lastname: Lim
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Simnick
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Chilkoti