title: Selective white matter involvement in a patient with late onset Krabbe disease: MR, MR spectroscopy, and diffusion tensor study.
abstract: The most frequent type of Krabbe disease has an infantile onset. Unusual slowly progressive adult forms have also been described. We described a different involvement of white matter tracts where magnetic resonance signal alterations were evident in a case of a patient affected by late-onset form of disease.
authors.affiliation: Department of Neuroradiology, S. Andrea Hospital, University "La Sapienza", Rome, Italy. andrea.romano@uniroma1.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Romano
authors.forename: Roberto
authors.initials: R
authors.lastname: De Simone
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Fasoli
authors.forename: Michele
authors.initials: M
authors.lastname: Ferrante
authors.forename: Valentina
authors.initials: V
authors.lastname: Cipriani
authors.forename: Luigi Maria
authors.initials: LM
authors.lastname: Fantozzi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Bozzao
mesh_terms: D000328:Adult; D017668:Age of Onset; D001921:Brain / Q000378:metabolism* / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007965:Leukodystrophy, Globoid Cell / Q000378:metabolism* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D009413:Nerve Fibers, Myelinated / Q000378:metabolism* / Q000473:pathology*; D009434:Neural Pathways / Q000378:metabolism / Q000473:pathology