title: Ectopic pituitary adenoma presenting as midline nasopharyngeal mass.
abstract: BACKGROUND
  Ectopic pituitary adenomas are extremely rare. We report a case of ectopic pituitary adenoma in the midline of the nasopharynx. This adenoma probably arose from the pharyngeal remnant of Rathke's pouch.
  
  
  METHODS
  We discuss a case of a lady who presented to our unit with 2 months history of dryness and sensation of lump in her throat and a long standing history of hypothyroidism. Examination of nasopharynx revealed a smooth and fluctuant midline mass. CT scan of nose and paranasal sinuses confirmed the midline mass with small defect communicating with the sphenoid sinus. An initial diagnosis of Thornwaldt's cyst was made and she underwent upper aerodigestive tract endoscopy and marsupialization of the mass. Histopathological examination revealed ectopic pituitary adenoma.
  
  
  CONCLUSIONS
  Ectopic pituitary adenoma is an important differential diagnosis for a midline nasopharyngeal mass. It is recommended that prior to surgical resection of midline nasopharyngeal mass biopsy is taken and MRI is performed.
authors.affiliation: Department of Otolaryngology, Waterford Regional Hospital, Dunmore Road, Waterford, Ireland. rohana.oconnell@gmail.com
authors.forename: R
authors.initials: R
authors.lastname: Ali
authors.forename: U
authors.initials: U
authors.lastname: Noma
authors.forename: M
authors.initials: M
authors.lastname: Jansen
authors.forename: D
authors.initials: D
authors.lastname: Smyth
mesh_terms: D000236:Adenoma / Q000378:metabolism / Q000473:pathology*; D003397:Craniopharyngioma / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000378:metabolism / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000473:pathology