[Thrombotic microangiopathies].
Thrombotic microangiopathies are disorders of microvascular occlusion and are characterized by thrombocytopenia and microangiopathic haemolytic anaemia. Varying additional signs and symptoms of organ ischaemia may be present. Thrombotic microangiopathies are pathophysiologically heterogenous disorders and include primarily thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome. Besides this, they may occur in association with certain diseases or drugs, or after allogeneic haematopoietic stem cell transplantation.
Studt
J-D
JD
Abteilung für Hämatologie, Universitätsspital Basel, Schweiz. studtj@uhbs.ch
D000743:Anemia, Hemolytic / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007511:Ischemia / Q000209:etiology; D008833:Microcirculation / Q000502:physiology; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D033581:Stem Cell Transplantation / Q000009:adverse effects; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy