Lumiracoxib inhibits cyclo-oxygenase 2 completely at the 50 mg dose: is liver toxicity avoidable by adequate dosing?
Hinz
B
B
Renner
B
B
Cheremina
O
O
Besz
D
D
Zolk
O
O
Brune
K
K
D056486:Chemical and Drug Induced Liver Injury; D051546:Cyclooxygenase 2 / Q000097:blood; D052246:Cyclooxygenase 2 Inhibitors / Q000008:administration & dosage*; D004008:Diclofenac / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009000:Monocytes / Q000201:enzymology
D052246:Cyclooxygenase 2 Inhibitors; D004008:Diclofenac; D051546:Cyclooxygenase 2; C473384:lumiracoxib