title: Coordination modes of a schiff base pentadentate derivative of 4-aminoantipyrine with cobalt(II), nickel(II) and copper(II) metal ions: synthesis, spectroscopic and antimicrobial studies.
abstract: Transition metal complexes of Co(II), Ni(II) and Cu(II) metal ions with general stoichiometry [M(L)X]X and [M(L)SO(4)], where M = Co(II), Ni(II) and Cu(II), L = 3,3'-thiodipropionic acid bis(4-amino-5-ethylimino-2,3-dimethyl-1-phenyl-3-pyrazoline) and X = NO(3)(-), Cl(-) and OAc(-), have been synthesized and structurally characterized by elemental analyses, molar conductance measurements, magnetic susceptibility measurements and spectral techniques like IR, UV and EPR. The nickel(II) complexes were found to have octahedral geometry, whereas cobalt(II) and copper(II) complexes were of tetragonal geometry. The covalency factor (beta) and orbital reduction factor (k) suggest the covalent nature of the complexes. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi, i.e. Alternaria brassicae, Aspergillus niger and Fusarium oxysporum and two bacteria, i.e. Xanthomonas compestris and Pseudomonas aeruginosa.
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, New Delhi, India. schandra_00@yahoo.com
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.forename: Deepali
authors.initials: D
authors.lastname: Jain
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Sharma
authors.forename: Pratibha
authors.initials: P
authors.lastname: Sharma
mesh_terms: D000528:Alternaria / Q000187:drug effects; D000675:Ampyrone / Q000031:analogs & derivatives*; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D005670:Fusarium / Q000187:drug effects; D009532:Nickel / Q000737:chemistry; D011422:Propionates / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011720:Pyrazoles / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014974:Xanthomonas / Q000187:drug effects
chemical_list: C534563:3,3'-thiodipropionic acid bis(4-amino-5-ethylimino-2,3-dimethyl-1-phenyl-3-pyrazoline); D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D011422:Propionates; D011720:Pyrazoles; D012545:Schiff Bases; D000675:Ampyrone; D003035:Cobalt; D003300:Copper; D009532:Nickel