Amide-directed alkenylation of sp(2) C-H Bonds catalyzed by a cationic Rh(I)/BIPHEP complex under mild conditions: dramatic rate acceleration by a 1-pyrrolidinecarbonyl group.
A cationic rhodium(I)/BIPHEP complex catalyzes amide-directed regioselective alkenylations of olefinic or aromatic sp(2) C-H bonds in good yields under mild reaction conditions. The use of a 1-pyrrolidinecarbonyl group as a directing group dramatically accelerates the reaction.
Shibata
Yu
Y
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan.
Otake
Yousuke
Y
Hirano
Masao
M
Tanaka
Ken
K