Templated amplification of a naphthalenediimide-based receptor from a donor-acceptor dynamic combinatorial library in water.
We report a dynamic combinatorial library that, upon binding of an electronically-complementary guest, produces in high yield a tetrameric receptor with flat hydrophobic, electron-deficient surfaces and flexible, water-soluble disulfide-containing linkers; analysis of the dependence of library composition on template concentration gives insight into the binding behaviours of the species involved.
Au-Yeung
Ho Yu
HY
University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge, UK.
Pengo
Paolo
P
Pantoş
G Dan
GD
Otto
Sijbren
S
Sanders
Jeremy K M
JK