[Management of nasal skull-base neoplasms with endoscopic minimally invasive technique: a report of 36 cases].
OBJECTIVE
To discuss the indication, efficacy and safety of endoscopic minimally invasive surgery technique in the management of nasal skull-base neoplasms.


METHODS
Thirty-six patients with nasal skull base neoplasms were treated from January 2000 to Jun 2004 under nasal endoscopy, including 16 nasopharyngeal fibroangioma, 8 sinus osteofibroma, 8 pituitary adenoma, 4 olfactory neuroblastoma. Pathology lab procedures were performed pre or post-operatively. The feeding artery of nasopharyngeal fibroangioma was selectively embolized with gelatin sponge before operation. All olfactory neuroblastoma and 2 pituitary adenoma received radiotherapy after operation.


RESULTS
Total or most of nasopharyngeal fibroangioma, sinus osteofibroma, olfactory neuroblastoma and pituitary adenoma were excised. Three cases presented complications of cerebrospinal fluid leakage, 2 cases were successfully mended with middle turbinate and muscle tissue respectively, another one gained self-healing after reducing the intracranial pressure and anti-inflammation. Followed up 4 to 8 years without recurrence for all patients. Seldom serious complications accrued.


CONCLUSIONS
When the indications are selected appropriately, nasal skull-base neoplasms, including benign and malignant, can be well treated with nasal endoscopic minimally invasive surgery.
Wei
Yong-xiang
YX
Department of Otorhinolaryngology Head and Neck Surgery, Capital Medical University, Beijing 100730, China. weiyongxiang@vip.sina.com
Han
De-min
DM
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004724:Endoscopy; D005260:Female; D018214:Fibroma, Ossifying / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009303:Nasopharyngeal Neoplasms / Q000601:surgery; D009447:Neuroblastoma / Q000601:surgery; D009666:Nose / Q000601:surgery; D009832:Olfactory Nerve / Q000473:pathology; D010911:Pituitary Neoplasms / Q000601:surgery; D019292:Skull Base Neoplasms / Q000601:surgery*; D055815:Young Adult