title: Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome.
abstract: The state of vasoplegia in immediate post-cardiopulmonary bypass period is characterized by severe hypotension, supranormal cardiac output, low systemic vascular resistance (SVR), and resistance to vasoconstrictors. We could successfully use induced mild hypothermia to increase SVR, and could avoid very high doses of nor-epinephrine (>0.3 mcg/kg/min) in the background of severe pulmonary hypertension (systolic pulmonary pressure> 90 mmHg). Its effects such as decreased oxygen demand, positive inotropy and better right ventricle performance probably helped to improve oxygenation in presence of pulmonary oedema.
authors.affiliation: Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. mukesh_tripathi@yahoo.com
authors.forename: Mukesh
authors.initials: M
authors.lastname: Tripathi
authors.forename: Prabhat Kumar
authors.initials: PK
authors.lastname: Singh
authors.forename: Naresh
authors.initials: N
authors.lastname: Kumar
authors.forename: Kailash Chandra
authors.initials: KC
authors.lastname: Pant
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007022:Hypotension / Q000209:etiology; D007036:Hypothermia, Induced; D008297:Male; D008946:Mitral Valve Stenosis / Q000150:complications / Q000601:surgery*; D011654:Pulmonary Edema / Q000209:etiology / Q000628:therapy; D012214:Rheumatic Heart Disease / Q000150:complications; D013577:Syndrome; D016896:Treatment Outcome; D014655:Vascular Resistance; D014664:Vasodilation