Green tea, black tea consumption and risk of lung cancer: a meta-analysis.
Studies investigating the association of green tea and black tea consumption with lung cancer risk have reported inconsistent findings. To provide a quantitative assessment of this association, we conducted a meta-analysis on the topic. Studies were identified by a literature search in PubMed from 1966 to November 2008 and by searching the reference lists of relevant studies. Summary relative risk (RR) estimates and their corresponding 95% confidence intervals (CIs) were calculated based on random-effects model. Our meta-analysis included 22 studies provided data on consumption of green tea or black tea, or both related to lung cancer risk. For green tea, the summary RR indicated a borderline significant association between highest green tea consumption and reduced risk of lung cancer (RR=0.78, 95% CI=0.61-1.00). Furthermore, an increase in green tea consumption of two cups/day was associated with an 18% decreased risk of developing lung cancer (RR=0.82, 95% CI=0.71-0.96). For black tea, no statistically significant association was observe through the meta-analysis (highest versus non/lowest, RR=0.86, 95% CI=0.70-1.05; an increment of two cups/day, RR=0.82, 95% CI=0.65-1.03). In conclusion, our data suggest that high or an increase in consumption of green tea but not black tea may be related to the reduction of lung cancer risk.
Tang
Naping
N
National Shanghai Center for New Drug Safety Evaluation and Research, Shanghai Institute of Pharmaceutical Industry, Zhangjiang Hi-Tech Park, Pudong, Shanghai, China. naping.tang@gmail.com
Wu
Yuemin
Y
Zhou
Bo
B
Wang
Bin
B
Yu
Rongbin
R
D028241:Camellia sinensis; D002681:China; D004326:Drinking; D005247:Feeding Behavior; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000517:prevention & control; D010936:Plant Extracts / Q000008:administration & dosage*; D039781:PubMed; D012307:Risk Factors; D013045:Species Specificity; D013662:Tea
D010936:Plant Extracts; D013662:Tea