[The mechanisms responsible for the development of diabetic nephroangiopathy].
Metabolic, hemodynamic, blood rheological, hormonal, immune, age- and other related mechanisms are involved in the development of nephroangiopathy in types 1 and 2 diabetes mellitus. The initial increase in glomerular filtration rapidly gives way to progressive sclerosis and hyalinosis of glomeruli and afferent and efferent arterioles. These changes can be arrested only in early stages of diabetic nephroangiopathy.
Saltykov
B B
BB
D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D055806:Microvessels / Q000378:metabolism / Q000503:physiopathology