title: Germ cell tumors of the brainstem: report on two cases with pulmonary complications and a review of the literature.
abstract: Intracranial germ cell tumors most commonly present in the pineal and suprasellar regions. Rare cases of brainstem germ cell tumors have been described. Here, we present two cases with brainstem germ cell tumors and review the current literature. The two patients did well, in terms of disease control, but have significant morbidity related to respiratory issues. One patient remains ventilator dependent and the second died from respiratory arrest.
authors.affiliation: Department of Neuro-Oncology, The Children's Hospital, Aurora, CO, USA.
authors.forename: Jenny
authors.initials: J
authors.lastname: Madden
authors.forename: Nicholas K
authors.initials: NK
authors.lastname: Foreman
authors.forename: Arthur K
authors.initials: AK
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D020295:Brain Stem Neoplasms / Q000150:complications* / Q000473:pathology*; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications* / Q000473:pathology*; D011878:Radiotherapy; D012131:Respiratory Insufficiency / Q000209:etiology*; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents