A novel HLA-Cw*0436 allele identified by haplotype-specific extraction and sequence-based typing.
A novel HLA-Cw*04 variant allele, Cw*0436, was identified in three members of a Korean family. This allele shows only one nucleotide difference from Cw*0411 in exon 2 at nucleotide position 268 (codon 90 GCC-->GAC), resulting in an amino acid change from Alanine (A) to Aspartic acid (D).
Lim
J
J
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim
Y
Y
Cho
B
B
Chung
N-G
NG
Bok
J-N
JN
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D005190:Family; D005838:Genotype; D015236:HLA-C Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D015236:HLA-C Antigens; C538924:HLA-C*04:36 antigen