Do low-protein diets work in chronic kidney disease patients?
Patients with chronic kidney disease have been advised for many years to reduce their protein intake. This review addresses the biochemical, pathophysiologic, and nutritional background that underlies this recommendation. The clinical and therapeutic evidence for prescribing such diets is addressed, as well as the potential caveats. A proposed method for managing and monitoring patients also is provided.
Fouque
Denis
D
Department of Nephrology, Hôpital Edouard Herriot, INSERM U870-University, Lyon, France. denis.fouque@chu-lyon.fr
Guebre-Egziabher
Fitsum
F
D018753:Diet, Protein-Restricted; D019317:Evidence-Based Medicine; D006801:Humans; D007676:Kidney Failure, Chronic / Q000178:diet therapy* / Q000503:physiopathology*; D011507:Proteinuria / Q000503:physiopathology / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic