Delayed-onset muscle injury and its modification by wheat gluten hydrolysate.
OBJECTIVE
We investigated the pattern of delayed-onset muscle injury in well-trained athletes after a competitive half-marathon and the effects of post-race intake of wheat gluten hydrolysate (WGH).


METHODS
Thirty well-trained college runners with a best time of 14-15 min over 5000 m raced in a half-marathon. Thereafter, they were divided into three groups based on finish times and given 0 (control), 10, or 20 g of WGH. Blood biochemical parameters were monitored at -1 d, +1 h, +1 d, and +2 d after the race. Data selected according to finish times and biochemical parameters were then analyzed.


RESULTS
Plasma creatine kinase activity peaked at 1 d after the race in the control group and correlated with post-race white blood cell counts. The post-race elevation of creatine kinase activity was dose-dependently suppressed by WGH.


CONCLUSIONS
Delayed-onset muscle injury peaked in well-trained distance runners at 1 d after a half-marathon and was dose-dependently suppressed by a post-race intake of WGH.
Koikawa
Natsue
N
Department of Sports Science, School of Health and Sports Science, Juntendo University, Chiba, Japan. koikawa@sakura.juntendo.ac.jp
Nakamura
Akira
A
Ngaoka
Isao
I
Aoki
Kazuhiro
K
Sawaki
Keisuke
K
Suzuki
Yoshio
Y
D000293:Adolescent; D003402:Creatine Kinase / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005983:Glutens / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects / Q000201:enzymology / Q000293:injuries* / Q000502:physiology; D011492:Protein Hydrolysates / Q000008:administration & dosage / Q000494:pharmacology*; D012420:Running / Q000502:physiology*; D014908:Triticum / Q000737:chemistry*; D055815:Young Adult
D011492:Protein Hydrolysates; D005983:Glutens; D003402:Creatine Kinase