Synthetic studies on N-alkoxyamines: a mild and broadly applicable route starting from nitroxide radicals and aldehydes.
A broad variety of 2,2,6,6-tetramethylpiperidine-based N-alkoxyamines were prepared in a newly found reaction. By means of a copper-catalyzed fragmentation reaction of aldehyde peroxides in the presence of TEMPO or TEMPO derivatives, N-alkoxyamines were obtained in moderate to good yields.
Schoening
Kai-Uwe
KU
Ciba Inc., WRO-1059, 4002 Basel, Switzerland. kai-uwe.schoening@ciba.com
Fischer
Walter
W
Hauck
Stefan
S
Dichtl
Alexander
A
Kuepfert
Michael
M