title: [Pulmonary embolism in a patient with large cell lung carcinoma during chemotherapy-case report].
abstract: The patient, a 64-year-old woman, was diagnosed as having large cell carcinoma(stageIV)eighteen months ago. She received long-term chemotherapy, and her disease stabilized. She was admitted to our hospital with dyspnea and diagnosed with a pulmonary embolism by chest computed tomography(CT)and angiography of pulmonary artery. As a result of thrombolytic therapy and anticoagulant therapy, the thrombus decreased in size and her condition improved. Insertion of a vena cava filter and continuation of anticoagulant therapy were performed to prevent recurrence of PE. In this case, there were many prothrombogenic factors such as advanced malignancy, a long period of chemotherapy, corticosteroids, granulocyte-colony stimulating factor(G-CSF)and decreased physical activity. Thrombosis is a frequent complication in cancer patients and represents an important cause of morbidity and mortality. Great care should be taken for complications of thrombosis in cancer treatment.
authors.affiliation: Dept. of Respiratory Medicine, Chugoku Rosai General Hospital, Japan.
authors.forename: Hideto
authors.initials: H
authors.lastname: Oshita
authors.forename: Junji
authors.initials: J
authors.lastname: Itai
authors.forename: Keitaro
authors.initials: K
authors.lastname: Omori
authors.forename: Naoki
authors.initials: N
authors.lastname: Okamoto
authors.forename: Yukikazu
authors.initials: Y
authors.lastname: Awaya
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018287:Carcinoma, Large Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants; D000970:Antineoplastic Agents