Silaphenylmercuric triflate catalyzed reactions: synthesis of a solid-supported mercuric salt catalyst.
Let it flow, let it flow: A procedure to generate the first solid-supported mercuric salt, silaphenylmercuric triflate, is described. Silaphenylmercuric triflate showed remarkable catalytic activity for an indole synthesis, furanoyne cyclization, arylyne cyclization, and tandem carbocyclizations. An efficient flow reaction system for indole synthesis and arylyne cyclization is also described (see figure).
Yamamoto
Hirofumi
H
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Sasaki
Ikuo
I
Hirai
Yuki
Y
Namba
Kosuke
K
Imagawa
Hiroshi
H
Nishizawa
Mugio
M
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis*; D008698:Mesylates / Q000138:chemical synthesis* / Q000737:chemistry*; D009941:Organomercury Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
D000480:Alkynes; D006571:Heterocyclic Compounds; D007211:Indoles; D008698:Mesylates; D009941:Organomercury Compounds; C030374:indole