title: Comparison of levo-bupivacaine and lidocaine for postoperative analgesia following septoplasty.
abstract: The aim of this study is to compare the efficacy of levo-bupivacaine, a long-acting local anesthetic and lidocaine in postoperative analgesia following septoplasty. 112 patients randomized into two groups were included in the study. 56 patients were operated using levo-bupivacaine and 56 using lidocaine as the local anesthetic. All patients were asked to mark their pain levels on a Visual analogue scale (VAS) at 1st, 2nd, 4th, 6trh 8th, 12th, and 24th hours postoperatively. In addition, the amount of analgesics used by each patient was recorded. The results indicated that the VAS scores of the levo-bupivacaine patients were significantly lower within the postoperative 4 hours (p < 0.05) compared to the lidocaine group. In the levobupivacaine patients the earliest time for analgesic need was delayed (p < 0.001) and the total amount of analgesics used was significantly lower when compared to lidocaine group (p < 0.001). In conclusion, levo-bupivacaine is effective for obtaining postoperative analgesia following septoplasty with local anesthesia. When compared to lidocaine, it increases the postoperative comfort of the patients by reducing pain levels.
authors.affiliation: Ankara Numune Education and Research Hospital, ENT Department, Ankara, Turkey. yfyilmaz@gmail.com
authors.forename: Yavuz Fuat
authors.initials: YF
authors.lastname: Yilmaz
authors.forename: Samet
authors.initials: S
authors.lastname: Ozlugedik
authors.forename: Ali
authors.initials: A
authors.lastname: Titiz
authors.forename: Anil
authors.initials: A
authors.lastname: Tuncay
authors.forename: Muge
authors.initials: M
authors.lastname: Ozcan
authors.forename: Adnan
authors.initials: A
authors.lastname: Unal
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000627:therapeutic use*; D002045:Bupivacaine / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D000077554:Levobupivacaine; D008012:Lidocaine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000601:surgery*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D012225:Rhinoplasty; D018709:Statistics, Nonparametric; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D000077554:Levobupivacaine; D002045:Bupivacaine