title: Spinal extradural angiolipoma: report of two cases and review of the literature.
abstract: Spinal angiolipomas are benign uncommon neoplasm composed of mature lipocytes admixed with abnormal blood vessels. They account for only 0.04-1.2% of all spinal tumors. We report two cases of lumbar extradural angiolipoma and review previously reported cases. We found 118 cases of spinal epidural angiolipoma (70 females and 48 males; age range 1.5-85 years, mean 44.03) spanning from 1890 to 2006. Prior to diagnosis 40.6% of the patients had weakness of the lower limbs. The interval between the initial symptoms and tumor diagnosis ranged from 1 day to 17 years (mean 20.2 months). Except for four cases diagnosed at autopsy, 109 patients underwent surgery and gross-total resection was performed in 79 cases (72.4%). Spinal angiolipomas are tumors containing angiomatous and lipomatous tissue, predominantly located in the mid-thoracic region. All angiolipomas show iso- or hyperintensity on T1-weighted images and hyperintensity on T2-weighted images and most lesions enhance with gadolinium administration. The treatment for spinal extradural angiolipomas is total surgical resection and no adjuvant therapy should be administered.
authors.affiliation: Neurosurgical Service, Department of Surgery, University of Santiago de Compostela, Santiago de Compostela, Spain. miguel.gelabert@usc.es
authors.forename: Miguel
authors.initials: M
authors.lastname: Gelabert-González
authors.forename: Alfredo
authors.initials: A
authors.lastname: García-Allut
mesh_terms: D000293:Adolescent; D018206:Angiolipoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D015174:Epidural Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D004824:Epidural Space / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D011128:Polyradiculopathy / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D012447:Sacrum / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013115:Spinal Canal / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome