Tissue remodeling and angiogenesis in asthma: the role of the eosinophil.
This review covers the role of eosinophils in asthma-associated tissue remodeling and angiogenesis focusing on angiogenesis which is a recently discovered feature of asthma. In addition, novel directions for eosinophil-targeted/angiogenesis-targeted pharmacological intervention are discussed as new approaches in the treatment of asthma.
Nissim Ben Efraim
A H
AH
Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Levi-Schaffer
F
F
D020533:Angiogenesis Inhibitors / Q000494:pharmacology; D000818:Animals; D001249:Asthma / Q000276:immunology / Q000503:physiopathology*; D004804:Eosinophils / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000503:physiopathology; D009389:Neovascularization, Pathologic / Q000503:physiopathology*
D020533:Angiogenesis Inhibitors