title: Pulse wave velocity as a marker of severity of coronary artery disease.
abstract: To determine whether pulse wave velocity (PWV) as a measure of arterial stiffness is a marker of coronary artery diseases (CAD), the authors did a cross-sectional study in 92 patients undergoing coronary angiography for suspected CAD. Arterial stiffness was assessed through recording PWV from the left carotid-right femoral arteries using an automated machine. The mean PWV was higher in patients with CAD than in those without CAD (11.13+/-0.91 vs 8.14+/-1.25 m/sec; P<.001). When the severity of CAD was expressed as 1-, 2-, and multiple-vessel disease, there was a significant association between the severity of CAD and PWV. PWV differed significantly with different categorical severity of CAD even when age and total cholesterol were controlled for. In a univariable analysis, PWV was higher with higher systolic blood pressure (P<.004). The authors conclude that arterial stiffness measured through PWV is an independent and complementary cardiovascular risk marker.
authors.affiliation: Cardiology Division, Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. ahmadalarhabi@yahoo.com
authors.forename: Ahmed Yahya
authors.initials: AY
authors.lastname: Alarhabi
authors.forename: Mohd Sapawi
authors.initials: MS
authors.lastname: Mohamed
authors.forename: Suhairi
authors.initials: S
authors.lastname: Ibrahim
authors.forename: Tee Meng
authors.initials: TM
authors.lastname: Hun
authors.forename: Kamarul Imran
authors.initials: KI
authors.lastname: Musa
authors.forename: Zurkurnai
authors.initials: Z
authors.lastname: Yusof
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D002339:Carotid Arteries / Q000503:physiopathology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D005263:Femoral Artery / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011674:Pulse; D012307:Risk Factors