title: Staphylococcal surgical site infections.
abstract: Staphylococcus aureus is the leading cause of surgical site infections (SSI) in the United States. In particular, SSI caused by methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a devastating complication, leading to increased mortality rates, increased length of hospitalization, and increased costs. Proven strategies for prevention of SSI caused by S aureus include addressing modifiable risk factors and correct choice and timing of antimicrobial prophylaxis. Other strategies, including decolonization and the use of vancomycin, remain controversial.
authors.affiliation: Division of Infectious Diseases, Duke University Medical Center, DUMC Box 3605, Durham, NC 27710, USA. dja@duke.edu
authors.forename: Deverick J
authors.initials: DJ
authors.lastname: Anderson
authors.forename: Keith S
authors.initials: KS
authors.lastname: Kaye
mesh_terms: D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification* / Q000502:physiology; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000382:microbiology*; D037521:Virulence Factors
chemical_list: D037521:Virulence Factors