title: [Brain sparing effect: from placental insufficiency to fetal circulatory adaptation].
abstract: The application and development of obstetric Doppler velocimetry provide a basis for the investigation of placental insufficiency and demonstrate the dynamic behavior of fetal circulation during hypoxia. In clinical practice, assessing hemodynamics in three vascular regions involved in pregnancy, namely the uterine, umbilical and middle cerebral arteries, has become routine. Roughly, the cerebral artery expresses the balance between uterine artery oxygen supply and umbilical artery oxygen uptake. Currently, when such balance is unfavorable, the fetal cardiac reserve is investigated by assessing the venous duct. However, determining and interpreting vascular resistance indexes is not an easy task. The starting point is to know the physiopathology of placental insufficiency and fetal circulatory adaptation through which Doppler confirmed its role in the assessment of fetal well-being.
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil. julivillasboas@hotmail.com
authors.forename: Juliana Marques Simões
authors.initials: JM
authors.lastname: Villas-Bôas
authors.forename: Izildinha
authors.initials: I
authors.lastname: Maestá
authors.forename: Marcos
authors.initials: M
authors.lastname: Consonni
mesh_terms: D000222:Adaptation, Physiological; D002536:Cerebral Arteries / Q000502:physiology; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D021041:Placental Circulation / Q000502:physiology*; D010927:Placental Insufficiency / Q000000981:diagnostic imaging*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000502:physiology