Deafness associated with acetaminophen and codeine abuse.
Ototoxicity associated with narcotic-acetaminophen combinations is not widely recognized. This can be the cause of severe-to-profound hearing loss that may be overlooked. Otolaryngologists who encounter patients with progressive hearing loss with no apparent cause should specifically ask about overuse of medications containing acetaminophen and a narcotic. Many patients feel that this form of medication is "safe" because it can be purchased over-the-counter.
Blakley
Brian W
BW
Department of Otolaryngology, University of Manitoba, Winnipeg, Manitoba. bblakley@exchange.hsc.mb.ca
Schilling
Heather
H
D000082:Acetaminophen / Q000506:poisoning*; D000328:Adult; D003061:Codeine / Q000506:poisoning*; D003638:Deafness / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019966:Substance-Related Disorders / Q000150:complications*
D000082:Acetaminophen; D003061:Codeine