Histoplasma-associated inflammatory pseudotumour of the kidney mimicking renal carcinoma.
A 56-year-old female, originally from Suriname, with an otherwise unremarkable previous medical history was found to have a renal mass highly suspicious for renal cancer for which a nephrectomy was performed. Within the kidney, a tumourous mass was found which, on histological examination, showed an inflammatory pseudotumour caused by Histoplasma capsulatum. Further investigations revealed an idiopathic CD4(+) lymphopenia. Mass lesions mimicking a malignant tumour caused by infection with Histoplasma have rarely been described. To the best of our knowledge, this is the first report of a Histoplasma-associated inflammatory pseudotumour mimicking cancer occurring in the kidney.
den Bakker
Michael A
MA
Department of Pathology, Erasmus MC-University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. m.denbakker@erasmusmc.nl
Goemaere
Natascha N T
NN
Severin
Juliëtte A
JA
Nouwen
J L
JL
Verhagen
Paul C M S
PC
D005260:Female; D006104:Granuloma, Plasma Cell / Q000209:etiology / Q000473:pathology*; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000150:complications*; D006801:Humans; D007674:Kidney Diseases / Q000473:pathology*; D007680:Kidney Neoplasms / Q000209:etiology / Q000473:pathology*; D008875:Middle Aged