Biomimetic synthesis toward the transtaganolides/basiliolides.
A concise biomimetic approach toward transtaganolides C and D involving an Ireland-Claisen rearrangement/intramolecular Diels-Alder reaction sequence suggesting the involvement of pericyclic reactions in the biosynthesis of these biologically active plant metabolites is presented. A final coupling reaction establishes the carbon framework of the transtaganolides.
Larsson
Rikard
R
Division of Organic Chemistry, Lund University, P.O. Box 124, S-221 00 Lund, Sweden.
Sterner
Olov
O
Johansson
Martin
M
D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry / Q000145:classification; D040761:Biomimetic Materials; D032701:Biomimetics; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure
D001688:Biological Products