Resting energy expenditure in manic episode.
OBJECTIVE
We aimed to assess the resting energy expenditure in bipolar I disorder, manic episode patients.


METHODS
Forty-two bipolar I disorder, manic episode patients that were treated in the inpatient psychiatry clinic of Trakya University Hospital and had met the necessary study criteria were included along with 27 controls. DSM-IV criteria and the Bech-Rafaelsen Mania Rating Scale were used to evaluate patients' diagnosis and severity of the manic episodes. The indirect calorimetry device was used to measure resting energy expenditure values.


RESULTS
Resting energy expenditure values of manic patients were found to be higher than those of the controls. Controls showed significant correlations between body mass index and resting energy expenditure, but manic patients did not exhibit similar correlations. There was also no relation between Bech-Rafaelsen Mania Rating Scale scores and resting energy expenditure values in manic patients.


CONCLUSIONS
We found significantly increased resting energy expenditure values in bipolar I disorder, manic episode patients. These findings suggest a possible clinical use of resting energy expenditure for evaluation of bipolar I disorder manic episode and also suggest resting energy expenditure as a possible biological marker.
Caliyurt
Okan
O
Department of Psychiatry, Trakya University Hospital, Edirne, Turkey. caliyurt@hotmail.com
Altiay
Gundeniz
G
D000328:Adult; D001714:Bipolar Disorder / Q000503:physiopathology*; D015992:Body Mass Index; D016009:Chi-Square Distribution; D004734:Energy Metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011659:Pulmonary Gas Exchange / Q000502:physiology; D012146:Rest / Q000502:physiology*; D012189:Retrospective Studies; D055815:Young Adult