title: Plasma copper and bone mineral density in osteopenia: an indicator of bone mineral density in osteopenic females.
abstract: Copper concentrations in blood plasma have been determined in 25 osteopenic females using inductively coupled plasma-mass spectrometry. A high degree of correlations has been demonstrated between the copper concentrations in plasma and the bone mineral density of the lumbar spine as measured using dual energy X-ray absorptiometry and quantitative computerized tomography. Results clearly indicate the involvement of copper in bone health and osteopenia. It is further suggested that plasma copper might be useful as a cheap and simple method indicative of bone mineral density in osteopenic postmenopausal females.
authors.affiliation: Institute of Diagnostic and Interventional Radiology, Klinikum-Nuernberg, Breslauer Strasse 201, Nuernberg, Germany. anwar.chaudhri@gmx.net
authors.forename: M Anwar
authors.initials: MA
authors.lastname: Chaudhri
authors.forename: W
authors.initials: W
authors.lastname: Kemmler
authors.forename: Igor
authors.initials: I
authors.lastname: Harsch
authors.forename: R J
authors.initials: RJ
authors.lastname: Watling
mesh_terms: D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000097:blood* / Q000503:physiopathology*; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D013058:Mass Spectrometry; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed
chemical_list: D003300:Copper