title: Demonstration of left ventricular dyssynchrony and resynchrony by ECG-gated SPECT with cardioGRAF in a patient with advanced heart failure and narrow QRS complex.
abstract: Accurate objective quantification of left ventricular (LV) dyssynchrony is a key to selecting candidates for cardiac resynchronization therapy (CRT), especially when screening among patients with a narrow QRS. CardioGRAF (cardio Gated single photon emission computed tomography Regional Assessment for left ventricular Function), a newly developed LV segmental time-volume analyzing program for myocardial perfusion single photon emission tomography, may be a promising tool. We describe the case of a 63-year-old male with non-ischemic cardiomyopathy with a QRS duration of 112 ms, in whom cardioGRAF successfully demonstrated baseline LV dyssynchrony and resynchronization achieved by CRT as evidenced by a significant decrease in dyssynchrony index (standard deviation of the duration from R to end-systole among 17 LV segments) x100/R-R interval).
authors.affiliation: Department of Cardiology, Ogaki Municipal Hospital, 4 -86 Minaminokawa-cho, Ogaki 503-0864, Japan. morishima-i@muc.biglobe.ne.jp
authors.forename: Itsuro
authors.initials: I
authors.lastname: Morishima
authors.forename: Takahito
authors.initials: T
authors.lastname: Sone
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Tsuboi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Mukawa
authors.forename: Michitaka
authors.initials: M
authors.lastname: Uesugi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Hayashi
mesh_terms: D000465:Algorithms; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006333:Heart Failure / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012984:Software; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014693:Ventricular Fibrillation / Q000150:complications / Q000000981:diagnostic imaging*