Pulse wave velocity as a marker of severity of coronary artery disease.
To determine whether pulse wave velocity (PWV) as a measure of arterial stiffness is a marker of coronary artery diseases (CAD), the authors did a cross-sectional study in 92 patients undergoing coronary angiography for suspected CAD. Arterial stiffness was assessed through recording PWV from the left carotid-right femoral arteries using an automated machine. The mean PWV was higher in patients with CAD than in those without CAD (11.13+/-0.91 vs 8.14+/-1.25 m/sec; P<.001). When the severity of CAD was expressed as 1-, 2-, and multiple-vessel disease, there was a significant association between the severity of CAD and PWV. PWV differed significantly with different categorical severity of CAD even when age and total cholesterol were controlled for. In a univariable analysis, PWV was higher with higher systolic blood pressure (P<.004). The authors conclude that arterial stiffness measured through PWV is an independent and complementary cardiovascular risk marker.
Alarhabi
Ahmed Yahya
AY
Cardiology Division, Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. ahmadalarhabi@yahoo.com
Mohamed
Mohd Sapawi
MS
Ibrahim
Suhairi
S
Hun
Tee Meng
TM
Musa
Kamarul Imran
KI
Yusof
Zurkurnai
Z
D000368:Aged; D000704:Analysis of Variance; D002339:Carotid Arteries / Q000503:physiopathology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D005263:Femoral Artery / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011674:Pulse; D012307:Risk Factors