LiOAc-catalyzed chemoselective deprotection of aryl silyl ethers under mild conditions.
An efficient and chemoselective deprotection protocol for aryl silyl ethers using LiOAc as a bifunctional Lewis acid-Lewis base catalyst was described. Acetates, epoxides, and aliphatic silyl ethers were preserved, whereas aryl TBS and TBDPS ethers can be differentiated.
Wang
Bing
B
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. wangbing@fudan.edu.cn
Sun
Hui-Xia
HX
Sun
Zhi-Hua
ZH