Demonstration of left ventricular dyssynchrony and resynchrony by ECG-gated SPECT with cardioGRAF in a patient with advanced heart failure and narrow QRS complex.
Accurate objective quantification of left ventricular (LV) dyssynchrony is a key to selecting candidates for cardiac resynchronization therapy (CRT), especially when screening among patients with a narrow QRS. CardioGRAF (cardio Gated single photon emission computed tomography Regional Assessment for left ventricular Function), a newly developed LV segmental time-volume analyzing program for myocardial perfusion single photon emission tomography, may be a promising tool. We describe the case of a 63-year-old male with non-ischemic cardiomyopathy with a QRS duration of 112 ms, in whom cardioGRAF successfully demonstrated baseline LV dyssynchrony and resynchronization achieved by CRT as evidenced by a significant decrease in dyssynchrony index (standard deviation of the duration from R to end-systole among 17 LV segments) x100/R-R interval).
Morishima
Itsuro
I
Department of Cardiology, Ogaki Municipal Hospital, 4 -86 Minaminokawa-cho, Ogaki 503-0864, Japan. morishima-i@muc.biglobe.ne.jp
Sone
Takahito
T
Tsuboi
Hideyuki
H
Mukawa
Hiroaki
H
Uesugi
Michitaka
M
Hayashi
Kazunori
K
D000465:Algorithms; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006333:Heart Failure / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012984:Software; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014693:Ventricular Fibrillation / Q000150:complications / Q000000981:diagnostic imaging*