title: [Chronic thromboembolic pulmonary hypertension].
abstract: Chronic thromboembolic pulmonary hypertension is characterized by the persistence of obstructive thromboemboli and pulmonary vascular remodelling in the open pulmonary arteries. The consequence is an increase in pulmonary vascular resistance and progressive right heart failure. Diagnosis is based on echocardiography, right heart catheterisation and ventilation-perfusion lung scan. Spiral CT and pulmonary angiography are required to assess operability. Pulmonary endarterectomy represents the treatment of choice. Antiproliferative treatments represent alternatives in the most severe and/or non operable patients.
authors.affiliation: Université Paris-Descartes, faculté de médecine, service de pneumologie et soins intensifs, Hôpital européen Georges-Pompidou, AP-HP, 75908 Paris Cedex 15, France. olivier.sanchez@egp.aphp.fr
authors.forename: Olivier
authors.initials: O
authors.lastname: Sanchez
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D004691:Endarterectomy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011379:Prognosis; D011655:Pulmonary Embolism / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016896:Treatment Outcome; D018497:Ventricular Dysfunction, Right / Q000209:etiology
chemical_list: D000925:Anticoagulants; D000959:Antihypertensive Agents; D010975:Platelet Aggregation Inhibitors