title: The Item-Specific Deficit Approach to evaluating verbal memory dysfunction: rationale, psychometrics, and application.
abstract: In the current study, we introduce the Item-Specific Deficit Approach (ISDA), a novel method for characterizing memory process deficits in list-learning data. To meet this objective, we applied the ISDA to California Verbal Learning Test (CVLT) data collected from a sample of 132 participants (53 healthy participants and 79 neurologically compromised participants). Overall, the ISDA indices measuring encoding, consolidation, and retrieval deficits demonstrated advantages over some traditional indices and indicated acceptable reliability and validity. Currently, the ISDA is intended for experimental use, although further research may support its utility for characterizing memory impairments in clinical assessments.
authors.affiliation: Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA. mwright@labiomed.org
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Wright
authors.forename: Ellen
authors.initials: E
authors.lastname: Woo
authors.forename: Maureen
authors.initials: M
authors.lastname: Schmitter-Edgecombe
authors.forename: Charles H
authors.initials: CH
authors.lastname: Hinkin
authors.forename: Eric N
authors.initials: EN
authors.lastname: Miller
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Gooding
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D008297:Male; D008433:Mathematics; D008569:Memory Disorders / Q000150:complications / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology*; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics / Q000379:methods*; D011930:Reaction Time / Q000502:physiology; D018709:Statistics, Nonparametric; D014706:Verbal Learning / Q000502:physiology*