[Biomarker].
Biomarkers play important roles in breast cancer management, i. e. diagnosis, treatment selection, and therapeutic monitoring. While the basic treatment strategy depends on the status of hormone receptors and HER2, other molecules are intensively studied for biomarkers to predict treatment efficacies. Gene expression profiles have been developed to predict prognosis and treatment efficacies. Circulating tumor cells and endothelial cells are drawing attention for therapeutic monitoring. It is essential to understand biomarkers for the progress of personalized medicine.
Ueno
Takayuki
T
Dept. of Surgery, Kyoto University Graduate School of Medicine, Japan.
Toi
Masakazu
M
D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D015415:Biomarkers / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D020249:Hormone Replacement Therapy; D006801:Humans; D011379:Prognosis; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism
D000970:Antineoplastic Agents; D015415:Biomarkers; D025521:Tumor Suppressor Proteins