A selective fluoroionophore based on BODIPY-functionalized magnetic silica nanoparticles: removal of Pb2+ from human blood.
Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb(2+) over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb(2+). The fluorescence receptor can remove 96 % of 100 ppb Pb(2+) from human blood, and can be useful and effective for the selective and rapid removal of Pb(2+) in vivo.
Lee
Hye Young
HY
Department of Chemistry and Research Institute of Natural Sciences and Environmental Biotechnology National Core Research Center, Gyeongsang National University, Jinju 660-701, Korea.
Bae
Doo Ri
DR
Park
Ji Chan
JC
Song
Hyunjoon
H
Han
Won Seok
WS
Jung
Jong Hwa
JH
D000327:Adsorption; D005453:Fluorescence; D006801:Humans; D007477:Ions / Q000032:analysis / Q000097:blood; D007854:Lead / Q000032:analysis / Q000097:blood*; D008280:Magnetics; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D007477:Ions; D014867:Water; D007854:Lead; D012822:Silicon Dioxide