Ytterbium(III) triflate-catalyzed amination of 1-cyclopropylprop-2-yn-1-ols as an expedient route to conjugated enynes.
Ytterbium(III) triflate-catalyzed ring opening of substituted 1-cyclopropyl-2-propyn-1-ols with sulfonamides as an efficient synthetic route to conjugated enynes is described herein. The reaction was operationally straightforward and accomplished in moderate to good yields and regioselective manner in all except one case under mild conditions.
Rao
Weidong
W
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Zhang
Xiaoxiang
X
Sze
Ella Min Ling
EM
Chan
Philip Wai Hong
PW
D000480:Alkynes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D003521:Cyclopropanes / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry
D000480:Alkynes; D003521:Cyclopropanes; D008698:Mesylates; D009942:Organometallic Compounds; D013449:Sulfonamides; C518808:ytterbium(III) triflate; C030797:cyclopropane