title: [Risk assessment and chemical safety under REACH].
abstract: Under the new European chemical legislation REACH (EG 1907/2006), dangerous properties of chemical substances will be evaluated and data gaps will be closed. This information is needed for other regulations, such as safety at the working place or for the safe handling of products. Existing knowledge on chemical compounds must be broadened because previous regulations have focused on high production volume compounds. The evaluation procedures needed too much time, and for the majority of non-evaluated substances a new strategy is needed. REACH places the duty for registration of substances with the producers and importers. Data gaps for risk evaluation will be closed. Competent authorities will be relieved from the primary risk evaluation of most substances. Alternative strategies of evaluation using previous information and non-animal testing approaches will be supported to avoid animal testing where appropriate. The new European chemical agency ECHA will use the provided information in order to identify very dangerous chemical substances which should be controlled by authorization of its use and the circumstances thereof.
authors.affiliation: Institut für Umwelttoxikologie, Martin-Luther-Universität, Halle/Saale, BRD. heidi.foth@medizin.uni-halle.de
authors.forename: Heidi
authors.initials: H
authors.lastname: Foth
mesh_terms: D026661:Clinical Trials Data Monitoring Committees / Q000458:organization & administration*; D005062:European Union / Q000458:organization & administration; D006078:Government Programs / Q000458:organization & administration*; D015386:Hazardous Substances / Q000145:classification / Q000592:standards* / Q000633:toxicity*; D012042:Registries; D018570:Risk Assessment / Q000458:organization & administration*; D012307:Risk Factors; D017751:Safety Management / Q000458:organization & administration*; D014116:Toxicology / Q000458:organization & administration
chemical_list: D015386:Hazardous Substances