Short-term clinical and microbiological evaluations of peri-implant diseases before and after mechanical anti-infective therapies.
OBJECTIVE
The aim of this study was to evaluate the clinical and microbiological effects of mechanical anti-infective therapies for mucositis and peri-implantitis.


METHODS
Subjects with at least one dental implant were assigned to healthy (n=10), mucositis (n=12) or peri-implantitis (n=13) groups. Implants with mucositis or peri-implantitis were decontaminated by means of teflon curettes and abrasive sodium carbonate air-powder, performed by an open flap for peri-implantitis and without surgery for mucositis. Visible plaque (PI), marginal bleeding (MB), bleeding on probing (BOP), suppuration (SUP), probing depth (PD) and relative clinical attachment level (rCAL) were assessed at baseline and at 3 months after therapies. At the same time points, submucosal plaque samples were collected from each implant and analyzed by Checkerboard DNA-DNA hybridization for 40 bacterial species.


RESULTS
All clinical parameters improved at 3 months post-therapy in mucositis and peri-implantitis groups (P<0.05). The mean reduction in rCAL (+/-SD) was 1.4+/-1.2 mm and 2.3+/-1.6 mm, and it was 1.3+/-1.2 mm and 3.1+/-1.7 mm in PD (+/-SD) for mucositis and peri-implantitis, respectively. Levels of Treponema denticola, Tanerella forsythia and Parvimonas micra, and of Fusobacterium nucleatum ss nucleatum, were significantly reduced after peri-implantitis therapy and after mucositis therapy, respectively (P<0.05). In addition, counts of Porphyromons gingivalis, Treponema socranskii and the proportions of red complex were reduced in both groups at 3 months after treatments (P<0.05).


CONCLUSIONS
Mechanical therapies alone were effective in treating mucositis and peri-implantitis over a period of 3 months. The open debridement procedure showed clinical and microbiological benefits on the treatment of peri-implantitis and could be safely used as a standard control group for future studies.
Máximo
Maria Beatriz
MB
Department of Periodontics, Dental Research Division, Guarulhos University, São Paulo, Brazil.
de Mendonça
Adriana Cutrim
AC
Renata Santos
Vanessa
V
Figueiredo
Luciene Cristina
LC
Feres
Magda
M
Duarte
Poliana Mendes
PM
D015373:Bacterial Typing Techniques; D003646:Debridement; D015921:Dental Implants / Q000382:microbiology*; D003773:Dental Plaque / Q000382:microbiology; D003774:Dental Plaque Index; D012534:Dental Scaling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D052016:Mucositis / Q000382:microbiology / Q000628:therapy; D009693:Nucleic Acid Hybridization; D010512:Periodontal Index; D010518:Periodontitis / Q000382:microbiology* / Q000628:therapy*; D013280:Stomatitis / Q000382:microbiology* / Q000628:therapy
D015921:Dental Implants