title: Voriconazole use for endemic fungal infections.
abstract: In a retrospective review of 24 patients with histoplasmosis, blastomycosis, or coccidioidomycosis treated with voriconazole (most for salvage therapy), the outcome was favorable (improved or stable) for 22 (95.8%) within 2 months of starting voriconazole and for 20 (83.3%) at the last follow-up. Prospective studies are required to determine its role in the treatment of endemic mycoses.
authors.affiliation: University of Nebraska Medical Center, Omaha, Nebraska, USA. afreifeld@unmc.edu
authors.forename: Alison
authors.initials: A
authors.lastname: Freifeld
authors.forename: Laurie
authors.initials: L
authors.lastname: Proia
authors.forename: David
authors.initials: D
authors.lastname: Andes
authors.forename: Larry M
authors.initials: LM
authors.lastname: Baddour
authors.forename: Janis
authors.initials: J
authors.lastname: Blair
authors.forename: Brad
authors.initials: B
authors.lastname: Spellberg
authors.forename: Sandra
authors.initials: S
authors.lastname: Arnold
authors.forename: Arnold
authors.initials: A
authors.lastname: Lentnek
authors.forename: L Joseph
authors.initials: LJ
authors.lastname: Wheat
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D001759:Blastomycosis / Q000188:drug therapy*; D003047:Coccidioidomycosis / Q000188:drug therapy*; D005260:Female; D006660:Histoplasmosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011743:Pyrimidines / Q000627:therapeutic use*; D012189:Retrospective Studies; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole