Exploration of the "traceless" reductive ligation of S-nitrosothiols.
The first "traceless" reductive ligation of S-nitrosothiols using phosphine ester/thioester conjugates is reported. Experiments also show that stable thioimidate compounds could be formed in the reaction between S-nitrosothiols and some phosphine-thioester substrates.
Zhang
Jiming
J
Department of Chemistry, Washington State University, Pullman, Washington 99164, USA.
Wang
Hua
H
Xian
Ming
M
D007096:Imidoesters / Q000138:chemical synthesis / Q000737:chemistry; D010084:Oxidation-Reduction; D026403:S-Nitrosothiols / Q000737:chemistry*
D007096:Imidoesters; D026403:S-Nitrosothiols