Rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in wound specimens and blood cultures: multicenter preclinical evaluation of the Cepheid Xpert MRSA/SA skin and soft tissue and blood culture assays.
A multicenter preclinical evaluation was conducted to evaluate the performance of two Cepheid Xpert assays for detection of methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus. Sensitivity was 97.1% and 98.3% for MRSA in wound and blood culture specimens, respectively. Sensitivity was 100% for S. aureus from both specimen types.
Wolk
D M
DM
University of Arizona/BIO5 Institute, Tucson, Arizona 85724-5059, USA. dwolk@email.arizona.edu
Struelens
M J
MJ
Pancholi
P
P
Davis
T
T
Della-Latta
P
P
Fuller
D
D
Picton
E
E
Dickenson
R
R
Denis
O
O
Johnson
D
D
Chapin
K
K
D001431:Bacteriological Techniques / Q000379:methods*; D001769:Blood / Q000382:microbiology*; D006801:Humans; D012680:Sensitivity and Specificity; D013203:Staphylococcal Infections / Q000175:diagnosis*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D014947:Wounds and Injuries / Q000382:microbiology*