Differences in clinical profiles of patients with Protobothrops mucrosquamatus and Viridovipera stejnegeri envenoming in Taiwan.
Envenoming by Protobothrops mucrosquamatus and Viridovipera stejnegeri accounts for the majority of venomous snakebites in Taiwan. We conducted a retrospective study to systematically examine the clinical manifestations and responses to antivenom therapy after P. mucrosquamatus and V. stejnegeri envenoming. Information on demographic characteristics, treatments, and systemic/local complications were abstracted from medical charts between 1991 and 2006. One hundred forty-nine patients with P. mucrosquamatus envenoming and 51 with V. stejnegeri envenoming were eligible for the final analysis, and they differed in terms of patient age, bite site, local bruising, proportion of patients needing >/= 3 vials of antivenom, and mean hospital stay. Univariate analysis revealed that P. mucrosquamatus envenoming had a higher risk of developing rhabdomyolysis, cellulitis, necrosis, and skin graft. Our findings suggested that P. mucrosquamatus envenoming was associated with a greater risk of severe clinical events, and monitoring for major clinical complications would be recommended.
Chen
Yen-Wen
YW
Department of Respiratory Therapy, Taipei Veterans General Hospital, Tapei, Taiwan. albert6369@gmail.com
Chen
Min-Hui
MH
Chen
Yen-Chia
YC
Hung
Dong-Zong
DZ
Chen
Chien-Kuang
CK
Yen
David Hung-Tsang
DH
Huang
Chun-I
CI
Lee
Chen-Hsen
CH
Wang
Lee-Min
LM
Yang
Chen-Chang
CC
D058186:Acute Kidney Injury / Q000209:etiology; D000328:Adult; D000368:Aged; D000818:Animals; D000997:Antivenins / Q000627:therapeutic use*; D003435:Crotalid Venoms; D003710:Demography; D004487:Edema / Q000209:etiology; D004890:Erythema / Q000209:etiology; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007902:Length of Stay; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D012206:Rhabdomyolysis / Q000209:etiology; D012909:Snake Bites / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D013624:Taiwan / Q000453:epidemiology; D013921:Thrombocytopenia / Q000209:etiology; D016896:Treatment Outcome; D014757:Viper Venoms; D017819:Viperidae / Q000033:anatomy & histology
D000997:Antivenins; D003435:Crotalid Venoms; D014757:Viper Venoms