Protein complexes: the evolution of symmetry.
Most proteins form symmetric, multimeric complexes. Modeling shows that a strong prevalence for symmetry among stable structures can account for this bias even in the absence of other adaptive advantages.
Plaxco
Kevin W
KW
Department of Chemistry and Biochemistry and Program in BioMolecular Science and Engineering, University of California, Santa Barbara, CA 93106, USA. kwp@chem.ucsb.edu
Gross
Michael
M
D008958:Models, Molecular; D046912:Multiprotein Complexes / Q000378:metabolism*; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*
D046912:Multiprotein Complexes; D011506:Proteins