Synthesis of diazacalix[8]arene and triazacalix[12]arene methyl ethers via intramolecular aryl amination.
Azacalixarenes derived from p-tert-butylphenol are generated by an intramolecular aryl amination strategy as the ring-closing step. The reaction produces the first examples of larger p-tert-butylcalixarenes with regioselective substitution of bridging methylenes with nitrogen atoms.
Lawson
Kenneth V
KV
Department of Chemistry, California State University, Sacramento, 6000 J Street, Sacramento, California 95819, USA.
Barton
Ashlee C
AC
Spence
John D
JD