Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: conditioning protocols and donor selection algorithms.
Allogeneic haematopoietic cell transplantation is an established curative treatment modality for patients with malignant and non-malignant haematological disorders. Since the first related umbilical cord blood transplant (UCBT) in 1988, the use of UCB as a stem cell source for transplantation has become a standard practice in many countries, with approximately 8000 such transplants having been performed worldwide to date.
Shaw
B E
BE
Section of Haemato-Oncology, Royal Marsden Hospital, Belmont, Sutton, Surrey SM2 5NG, UK. bshaw@doctors.org.uk
Veys
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Pagliuca
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Addada
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Cook
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Craddock
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Gennery
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Goldman
J
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Mackinnon
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Madrigal
J A
JA
Marks
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Navarrete
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Potter
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Querol
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Regan
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Russell
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Hough
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D000465:Algorithms; D036101:Cord Blood Stem Cell Transplantation / Q000592:standards*; D046148:Donor Selection / Q000592:standards*; D006402:Hematologic Diseases / Q000628:therapy; D006801:Humans; D017410:Practice Guidelines as Topic; D019172:Transplantation Conditioning / Q000592:standards*; D014184:Transplantation, Homologous; D006113:United Kingdom