title: Tandem concurrent processes: one-pot single-catalyst biohydrogen transfer for the simultaneous preparation of enantiopure secondary alcohols.
abstract: A novel one-pot tandem biohydrogen transfer process to concurrently obtain two enantiopure sec-alcohols is presented; thus, using a suitable single enzyme and a catalytic amount of cofactor, several interesting building blocks could be easily achieved in an enantiocomplementary fashion, minimizing dramatically the quantity of reagents usually employed in the "coupled-substrate" approach.
authors.affiliation: Departamento de Química Orgánica e Inorgánica, Instituto Universitario de Biotecnología de Asturias, University of Oviedo, 33006 Oviedo, Spain.
authors.forename: Fabricio R
authors.initials: FR
authors.lastname: Bisogno
authors.forename: Iván
authors.initials: I
authors.lastname: Lavandera
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Kroutil
authors.forename: Vicente
authors.initials: V
authors.lastname: Gotor
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry / Q000378:metabolism; D000438:Alcohols / Q000737:chemistry* / Q000378:metabolism; D001419:Bacteria / Q000201:enzymology; D055162:Biocatalysis; D006859:Hydrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D006859:Hydrogen; D000426:Alcohol Dehydrogenase