title: The controlled and sustained release of a fungicide from starch and alginate beads.
abstract: This paper describes the synthesis of starch and alginate beads as controlled release formulations. Different formulations of the fungicide, thiram, were prepared by using BaCl(2) and AlCl(3) as crosslinkers. The beads thus formed were characterized by FTIR and swelling studies. Formulation characteristics like entrapment efficiency, bead size, percentage equilibrium swelling have been evaluated. The release studies of the fungicide from the beads were carried out in vitro and in soil columns. The beads prepared with AlCl(3) have shown more swelling as well as the fungicide release in comparison to beads prepared with BaCl(2). From the soil column studies it was observed that the release of pesticide from the beads occurred in very controlled and sustained manner.
authors.affiliation: Department of Chemistry, Himachal Pradesh University, Shimla, H.P., India. baljitsinghhpu@yahoo.com
authors.forename: Baljit
authors.initials: B
authors.lastname: Singh
authors.forename: D K
authors.initials: DK
authors.lastname: Sharma
authors.forename: Atul
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000464:Alginates / Q000737:chemistry*; D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000737:chemistry; D017609:Barium Compounds / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D002712:Chlorides / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000737:chemistry*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008863:Microspheres; D017550:Spectroscopy, Fourier Transform Infrared; D013213:Starch / Q000737:chemistry*
chemical_list: D000464:Alginates; D017607:Aluminum Compounds; D017609:Barium Compounds; D002712:Chlorides; D003432:Cross-Linking Reagents; D003692:Delayed-Action Preparations; D005659:Fungicides, Industrial; D006603:Hexuronic Acids; C024986:barium chloride; D000077410:Aluminum Chloride; D020723:Glucuronic Acid; D013213:Starch