The Ukrainian-American study of leukemia and related disorders among Chornobyl cleanup workers from Ukraine: II. Estimation of bone marrow doses.
After the accident that took place on 26 April 1986 at the Chornobyl nuclear power plant, hundreds of thousands of cleanup workers were involved in emergency measures and decontamination activities. In the framework of an epidemiological study of leukemia and other related blood diseases among Ukrainian cleanup workers, individual bone marrow doses have been estimated for 572 cases and controls. Because dose records were available for only about half of the study subjects, a time-and-motion method of dose reconstruction that would be applicable to all study subjects, whether dead or alive, was developed. The doses were calculated in a stochastic mode, thus providing estimates of uncertainties. The arithmetic mean individual bone marrow doses were found to range from 0.00004 to 3,300 mGy, with an average value of 87 mGy over the 572 study subjects. The uncertainties, characterized by the geometric standard deviation of the probability distribution of the individual dose, varied from subject to subject and had a median value of about 2. These results should be treated as preliminary; it is likely that the dose calculations and particularly the uncertainty estimates will be improved in the follow-up of this effort.
Chumak
Vadim V
VV
Research Center for Radiation Medicine, Academy of Medical Sciences of Ukraine, Kyiv, Ukraine.
Romanenko
Anatoly Ye
AY
Voillequé
Paul G
PG
Bakhanova
Elena V
EV
Gudzenko
Natalya
N
Hatch
Maureen
M
Zablotska
Lydia B
LB
Golovanov
Ivan A
IA
Luckyanov
Nickolas K
NK
Sholom
Sergey V
SV
Kryuchkov
Viktor P
VP
Bouville
André
A
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000528:radiation effects*; D016022:Case-Control Studies; D047852:Chernobyl Nuclear Accident; D015331:Cohort Studies; D052918:Environmental Restoration and Remediation; D006801:Humans; D007938:Leukemia / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000453:epidemiology; D009190:Myelodysplastic Syndromes / Q000453:epidemiology; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D016273:Occupational Exposure; D011829:Radiation Dosage; D011874:Radiometry; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D013997:Time Factors; D014455:Ukraine / Q000453:epidemiology; D014481:United States