title: [Biomarker].
abstract: Biomarkers play important roles in breast cancer management, i. e. diagnosis, treatment selection, and therapeutic monitoring. While the basic treatment strategy depends on the status of hormone receptors and HER2, other molecules are intensively studied for biomarkers to predict treatment efficacies. Gene expression profiles have been developed to predict prognosis and treatment efficacies. Circulating tumor cells and endothelial cells are drawing attention for therapeutic monitoring. It is essential to understand biomarkers for the progress of personalized medicine.
authors.affiliation: Dept. of Surgery, Kyoto University Graduate School of Medicine, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ueno
authors.forename: Masakazu
authors.initials: M
authors.lastname: Toi
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D015415:Biomarkers / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D020249:Hormone Replacement Therapy; D006801:Humans; D011379:Prognosis; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers; D025521:Tumor Suppressor Proteins