Feline digital phaeohyphomycosis due to Exophiala jeanselmei.
The black nodule measuring 1 cm in diameter developed in the base of nail of an 8-year-old Japanese domestic male cat. Histological examination of the excised nodule revealed a granulomatous lesion extending from the epidermis to adjacent bone. The lesion was consisted of diffuse infiltration of macrophages with epithelioid cells and multinucleated giant cells. These macrophages contained a few to numerous yeast-like brown pigmented fungus cells with a spherical shape and dark thick wall. The PCR amplification with universal primers of the 28S ribosomal RNA gene yielded a 628-bp fragment and the direct sequence confirmed that the diagnosis of the lesion was phaeohyphomycosis caused by the pathogenic dematiaceous fungus, Exophiala jeanselmei.
Maeda
Hirofumi
H
College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
Shibuya
Hisashi
H
Yamaguchi
Yoko
Y
Miyoshi
Takuma
T
Irie
Mitsuhiro
M
Sato
Tsuneo
T
D000818:Animals; D002371:Cat Diseases / Q000382:microbiology* / Q000601:surgery; D002415:Cats; D005093:Exophiala / Q000145:classification*; D005534:Foot Diseases / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D009181:Mycoses / Q000382:microbiology / Q000601:surgery / Q000662:veterinary*