Distributions of the endocrine cells in the gastrointestinal tract of nectarivorous and sanguivorous bats: a comparative immunocytochemical study.
The present study was conducted to clarify the influence of feeding habits on regional distribution and relative frequency of endocrine cells secreting cholecystokinin (CCK), gastrin (GAS), serotonin (5-HT) and enteroglucagon (GLUC) in the nectarivorous Anoura geoffroyi and Glossophaga soricina and the sanguivorous Desmodus rotundus bats of the Phyllostomidae family, by specific immunohistochemical methods. The regional distribution and frequency of the different types of endocrine cells varied according to their location in the GIT. 5-HT immunoreactive cells (IR), detected throughout the GIT of three bats, were the most predominant gastrointestinal endocrine cells. GAS-IR cells in A. geoffroyi were found at the base of the pyloric gland, while in G. soricina they could also be observed in the middle to basal portions of the gland. GLUC-IR cells were located in the fundic region of A. geoffroyi, G. soricina and D. rotundus. These endocrine cells were more abundant in the sanguivorous bat. In nectarivorous bats were compared to sanguivorous bat, which differ in dietary habits, difference in the distribution and relative frequency of gut endocrine cells would be predicted. The absence of some, and decrease in frequency of other, gastrointestinal endocrine cells may reflect, in part, its interspecies differences or dietary habits.
Machado-Santos
Clarice
C
Postgraduate Program in Animal Biology, Rio de Janeiro Federal Rural University (UFRRJ), 890-000 Seropédica, RJ, Brazil. claricemachado@yahoo.com.br
Nascimento
Aparecida Alves do
AA
Peracchi
Adriano Lúcio
AL
Mikalauskas
Jefferson Simanas
JS
Rocha
Patrício Adriano
PA
Sales
Armando
A
D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D002685:Chiroptera / Q000033:anatomy & histology* / Q000378:metabolism; D002766:Cholecystokinin / Q000378:metabolism; D004063:Digestion / Q000502:physiology*; D004435:Eating / Q000502:physiology; D019858:Enteroendocrine Cells / Q000166:cytology* / Q000378:metabolism; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism; D005755:Gastrins / Q000378:metabolism; D041981:Gastrointestinal Tract / Q000166:cytology* / Q000378:metabolism; D004763:Glucagon-Like Peptides / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D012701:Serotonin / Q000378:metabolism; D013045:Species Specificity; D013270:Stomach / Q000166:cytology
D005755:Gastrins; D012701:Serotonin; D004763:Glucagon-Like Peptides; D002766:Cholecystokinin