title: Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion.
abstract: The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial. In this study, 28 New Zealand white male rabbits were randomly divided into five groups. Group A (n = 8), the control group, underwent a sham operation on the unilateral testis without inducing testicular torsion. In groups B, C, and D (n = 5 each), unilateral testicular torsion was induced, and, after 3, 6 or 24 h, respectively, detorsion was performed. In group E (n = 5), permanent unilateral testicular torsion was applied. Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages: pre-torsion (preopration), immediately post-torsion (postopration), pre-detorsion, immediately post-detorsion, and late-stage post-detorsion (6-12 h post-detorsion in groups B-D) or at a similar time point (15-21 h post-torsion in group E). Time-intensity curves were generated, and the following parameters were derived and analyzed: arrival time, time to peak intensity, peak intensity, and half-time of the descending peak intensity. The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side (P < 0.05), which increased with prolonged testicular torsion of the other testis. This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion.
authors.affiliation: Department of Ultrasound, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai 200025, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Zhan
authors.forename: Zhou-Jun
authors.initials: ZJ
authors.lastname: Shen
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Rui
authors.forename: Chen
authors.initials: C
authors.lastname: Lv
authors.forename: Man
authors.initials: M
authors.lastname: Chen
authors.forename: Jian-Qiao
authors.initials: JQ
authors.lastname: Zhou
authors.forename: Ping
authors.initials: P
authors.lastname: Zhou
authors.forename: Mi
authors.initials: M
authors.lastname: Zhou
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D000818:Animals; D003287:Contrast Media; D004195:Disease Models, Animal; D008297:Male; D011817:Rabbits; D012039:Regional Blood Flow / Q000502:physiology*; D013086:Spermatic Cord Torsion / Q000473:pathology* / Q000503:physiopathology; D013737:Testis / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D003287:Contrast Media