Geophagy (Soil-eating) in relation to Anemia and Helminth infection among HIV-infected pregnant women in Tanzania.
Geophagy, the regular and deliberate consumption of soil, is prevalent among pregnant women in sub-Saharan Africa. We examined the associations of geophagy with anemia and helminth infection among 971 human immunodeficiency virus (HIV)-positive pregnant women in Tanzania. About 29% of pregnant women regularly consumed soil. Occupation, marital status, and gestational age were associated with geophagy. Ascaris lumbricoides infection was associated with the prevalence of geophagy (adjusted-prevalence ratio 1.81; 95% confidence interval [CI] = 1.37-2.40); however, hookworm, Trichuris trichiura, and Strongyloides stercoralis showed no association. Anemia and red blood cell characteristics suggestive of iron deficiency were strongly correlated with geophagy at baseline. In longitudinal analyses, we found evidence suggesting that soil consumption may be associated with an increased risk of anemia (adjusted-relative risk 1.16; 95% CI = 0.98-1.36) and a lower hemoglobin concentration (adjusted-mean difference -3.8 g/L; 95% CI [-7.3, -0.4]). Pregnant women should be informed about the potential risks associated with soil consumption.
Kawai
Kosuke
K
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA. kkawai@hsph.harvard.edu
Saathoff
Elmar
E
Antelman
Gretchen
G
Msamanga
Gernard
G
Fawzi
Wafaie W
WW
D000328:Adult; D000740:Anemia / Q000150:complications* / Q000453:epidemiology* / Q000469:parasitology / Q000821:virology; D000818:Animals; D001196:Ascariasis / Q000150:complications; D017164:Ascaris lumbricoides / Q000302:isolation & purification; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000517:prevention & control / Q000635:transmission; D006373:Helminthiasis / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008137:Longitudinal Studies; D010842:Pica / Q000150:complications / Q000382:microbiology* / Q000821:virology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000469:parasitology* / Q000821:virology*; D011256:Pregnancy Outcome; D012307:Risk Factors; D012959:Socioeconomic Factors; D012987:Soil; D013636:Tanzania; D014801:Vitamin A / Q000627:therapeutic use
D012987:Soil; D014801:Vitamin A