title: Catalyzed vinylogous Mukaiyama aldol reactions with controlled enantio- and diastereoselectivities.
abstract: In control: A new catalytic vinylogous Mukaiyama aldol reaction provides products with high diastereo- and enantioselectivities (up to 99 % de and ee; see scheme). The relative and absolute stereochemistry of a representative product was rigorously assigned by NMR and CD spectroscopies (measured and calculated), X-ray diffraction, and quantum-chemical calculations.
authors.affiliation: Institut für Organische Chemie der RWTH Aachen University, Landoltweg 1, 52056 Aachen, Germany.
authors.forename: Marcus
authors.initials: M
authors.lastname: Frings
authors.forename: Iuliana
authors.initials: I
authors.lastname: Atodiresei
authors.forename: Jan
authors.initials: J
authors.lastname: Runsink
authors.forename: Gerhard
authors.initials: G
authors.lastname: Raabe
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm