The CatWalk method: assessment of mechanical allodynia in experimental chronic pain.
The CatWalk gait analysis system has recently been suggested as a rapid and objective alternative method over the von Frey test to assess mechanical allodynia in chronic neuropathic pain models. Our results demonstrate that no correlation exists between the development of mechanical allodynia and changes in CatWalk-gait parameters in a chronic inflammatory pain model. Hence, the use of the CatWalk in assessment of experimental chronic pain is discussed.
Gabriel
Anne F
AF
Department of Anesthesiology, Academic Hospital Maastricht, 6202 AZ Maastricht, The Netherlands. a.gabriel@np.unimaas.nl
Marcus
Marco A E
MA
Walenkamp
Geert H I M
GH
Joosten
Elbert A J
EA
D000818:Animals; D002908:Chronic Disease; D017076:Computer-Aided Design; D004195:Disease Models, Animal; D005121:Extremities / Q000294:innervation / Q000503:physiopathology*; D005684:Gait; D006941:Hyperesthesia / Q000503:physiopathology* / Q000523:psychology; D007249:Inflammation / Q000150:complications; D008297:Male; D009437:Neuralgia / Q000503:physiopathology* / Q000523:psychology; D010147:Pain Measurement / Q000379:methods*; D017288:Pain Threshold / Q000523:psychology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors