title: Conductive single-walled carbon nanotube substrates modulate neuronal growth.
abstract: We used conductive nanotube films as substrates with which we could systematically vary the conductance to see how this property affects neuronal growth. Here we show that nanotube substrates in a narrow range of conductivity promote the outgrowth of neurites with a decrease in the number of growth cones as well as an increase in cell body area, while at higher conductance these effects disappear.
authors.affiliation: Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy & Nanotechnology Laboratories, Civitan International Research Center, Evelyn F. McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA.
authors.forename: Erik B
authors.initials: EB
authors.lastname: Malarkey
authors.forename: Kirk A
authors.initials: KA
authors.lastname: Fisher
authors.forename: Elena
authors.initials: E
authors.lastname: Bekyarova
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Robert C
authors.initials: RC
authors.lastname: Haddon
authors.forename: Vladimir
authors.initials: V
authors.lastname: Parpura
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D049109:Cell Proliferation; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004553:Electric Conductivity; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure*; D009474:Neurons / Q000166:cytology* / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D037742:Nanotubes, Carbon