Concurrent Langerhans cell histiocytosis and nephroblastoma.
Both Langerhans cell histiocytosis (LCH) and nephroblastoma are rare in children. We report herein the first case of a patient with both diseases concurrently. A 2-year-old female presented with bone pain and swelling of the right humerus. As a result of the local incision biopsy, she was diagnosed as LCH. A nephroblastoma of the left kidney was discovered during her staging work-up. After complete resection of the nephroblastoma, she received standard chemoradiotherapy for nephroblastoma. She is alive without relapse 14 months after initial presentation.
Narui
Ryoko
R
Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yagasaki
Hiroshi
H
Takahashi
Yoshiyuki
Y
Hama
Asahito
A
Nishio
Nobuhiro
N
Muramatsu
Hideki
H
Shimoyama
Yoshie
Y
Kojima
Seiji
S
D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000150:complications* / Q000000981:diagnostic imaging