title: Ytterbium(III) triflate-catalyzed amination of 1-cyclopropylprop-2-yn-1-ols as an expedient route to conjugated enynes.
abstract: Ytterbium(III) triflate-catalyzed ring opening of substituted 1-cyclopropyl-2-propyn-1-ols with sulfonamides as an efficient synthetic route to conjugated enynes is described herein. The reaction was operationally straightforward and accomplished in moderate to good yields and regioselective manner in all except one case under mild conditions.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Weidong
authors.initials: W
authors.lastname: Rao
authors.forename: Xiaoxiang
authors.initials: X
authors.lastname: Zhang
authors.forename: Ella Min Ling
authors.initials: EM
authors.lastname: Sze
authors.forename: Philip Wai Hong
authors.initials: PW
authors.lastname: Chan
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D003521:Cyclopropanes / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry
chemical_list: D000480:Alkynes; D003521:Cyclopropanes; D008698:Mesylates; D009942:Organometallic Compounds; D013449:Sulfonamides; C518808:ytterbium(III) triflate; C030797:cyclopropane