Impact of antidepressant use on gastric bypass surgery patients' weight loss and health-related quality-of-life outcomes.
BACKGROUND
Psychological factors may be predictive of post-surgical adjustment and successful outcomes in obesity-surgery populations.


OBJECTIVE
The authors compared post-gastric bypass surgery (GBS) outcomes of patients being given active psychotropic treatment for depression, with those of patients without treatment or identifiable need for treatment at enrollment.


METHODS
Outcome measures included weight and repeated administration of the Medical Outcome Survey Short Form-36 (SF-36).


RESULTS
There was no impact of antidepressant treatment on GBS patients' weight loss or SF-36 outcomes.


CONCLUSIONS
Therefore, patients with actively treated depression should be expected to have GBS outcomes equivalent to those of patients without identifiable psychiatric illness or treatment.
Love
Robert J
RJ
Department of Psychiatry, Wilford Hall Medical Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78249, USA. Robert.Love2@dover.af.mil
Love
Ashley S
AS
Bower
Steven
S
Carlos Poston
Walker S
WS
D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015897:Comorbidity; D003866:Depressive Disorder / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D015390:Gastric Bypass / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology / Q000523:psychology / Q000601:surgery*; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D013781:Texas / Q000453:epidemiology; D016896:Treatment Outcome; D015431:Weight Loss / Q000187:drug effects*; D055815:Young Adult
D000928:Antidepressive Agents