title: Lumiracoxib inhibits cyclo-oxygenase 2 completely at the 50 mg dose: is liver toxicity avoidable by adequate dosing?
authors.forename: B
authors.initials: B
authors.lastname: Hinz
authors.forename: B
authors.initials: B
authors.lastname: Renner
authors.forename: O
authors.initials: O
authors.lastname: Cheremina
authors.forename: D
authors.initials: D
authors.lastname: Besz
authors.forename: O
authors.initials: O
authors.lastname: Zolk
authors.forename: K
authors.initials: K
authors.lastname: Brune
mesh_terms: D056486:Chemical and Drug Induced Liver Injury; D051546:Cyclooxygenase 2 / Q000097:blood; D052246:Cyclooxygenase 2 Inhibitors / Q000008:administration & dosage*; D004008:Diclofenac / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009000:Monocytes / Q000201:enzymology
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D004008:Diclofenac; D051546:Cyclooxygenase 2; C473384:lumiracoxib