A simple integrated system for electrophysiologic recordings in animals.
This technical note describes a modification to a fundus camera that permits simultaneous recording of pattern electroretinograms (pERGs) and pattern visual evoked potentials (pVEPs). The modification consists of placing an organic light-emitting diode (OLED) in the split-viewer pathway of a fundus camera, in a plane conjugate to the subject's pupil. In this way, a focused image of the OLED can be delivered to a precisely known location on the retina. The advantage of using an OLED is that it can achieve high luminance while maintaining high contrast, and with minimal degradation over time. This system is particularly useful for animal studies, especially when precise retinal positioning is required.
Johnson
Mary A
MA
The Department of Ophthalmology and Visual Sciences, The University of Maryland School of Medicine, Baltimore, MD, 21201, USA. mjohnson@umaryland.edu
Slater
Bernard J
BJ
Miller
Neil R
NR
Bernstein
Steven L
SL
Flower
Robert W
RW
D000818:Animals; D000830:Animals, Laboratory; D003626:Data Display; D004596:Electroretinography / Q000295:instrumentation*; D004867:Equipment Design; D005074:Evoked Potentials, Visual; D005654:Fundus Oculi; D008029:Lighting / Q000295:instrumentation; D008253:Macaca mulatta