3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters.
Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.
Kang
Jaskiranjit
J
Department of Chemistry, University College London, 20 Gordon Street, London, UK.
Richardson
Jonathan P
JP
Macmillan
Derek
D
D015097:3-Mercaptopropionic Acid / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D011506:Proteins / Q000138:chemical synthesis* / Q000737:chemistry
D010455:Peptides; D011506:Proteins; D015097:3-Mercaptopropionic Acid