Intraocular pressure after cataract surgery using Provasc, Viscoat either separately or in combination.
OBJECTIVE
To compare the intraocular pressure values after small-incision cataract surgery using either Provisc or Viscoat, separately or in combination.


METHODS
Prospective, randomized and masked clinical study.


METHODS
147 eyes of 147 consecutive cataract patients.


METHODS
The patients were randomly assigned to receive either Provisc (P group), Viscoat (V group) or both (V+P group) and intraocular pressure was measured at 1, 2, 3, 6, 9 and 24 h after surgery.


RESULTS
There were no statistically significant differences in intraocular pressure between the P and V+P group at any point in time during the follow-up period (p>0.05); however, in the V group the intraocular pressure was higher than in the other 2 groups at 1 h (p=0.005 and p=0.006 respectively) and 2 h (p<0.001 and p<0.001 respectively). In the V group, intraocular pressure was also higher than the P group at 3 h (p<0.001). Over 50% of patients from the V group had intraocular pressure values of 30 mmHg and over after 2 h and 3 h from surgery. There were no statistically significant differences between the study groups concerning the intraocular pressure values measured at 6 h, 9 h and 24 h postoperatively (p>0.05).


CONCLUSIONS
Viscoat results more frequently in high intraocular pressure values during the initial 6 h after small-incision cataract surgery with frequent cases in which the intraocular pressure could increase over 30 mmHg; therefore, close follow-up of these patients is necessary.
Chiseliţă
D
D
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
Danielescu
C
C
Gherghel
Doina
D
D000368:Aged; D000465:Algorithms; D000704:Analysis of Variance; D002387:Cataract Extraction / Q000379:methods; D002807:Chondroitin / Q000008:administration & dosage*; D002809:Chondroitin Sulfates / Q000008:administration & dosage*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D007429:Intraocular Pressure / Q000187:drug effects*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011184:Postoperative Period; D011446:Prospective Studies; D016896:Treatment Outcome
D004338:Drug Combinations; C501944:chondroitin sulfate, sodium hyaluronate drug combination; D006820:Hyaluronic Acid; D002807:Chondroitin; D002809:Chondroitin Sulfates