title: Intraoperative anaphylaxis due to gelofusine in a patient undergoing intramedullary nailing of the femur: a case report.
abstract: BACKGROUND
  Although uncommon, anaphylaxis due to a colloid plasma expander can occur peri-operatively
  
  
  METHODS
  We present a case of an intra-operative cardiac arrest in a 72 year old Caucasian male patient who underwent prophylactic intramedullary nailing for a proximal femoral metastasis from prostate cancer. The patient was resuscitated successfully and the procedure was completed uneventfully. Elevated serum tryptase levels confirmed the diagnosis of an anaphylactic reaction and positive allergy skin prick testing identified gelofusine as the causative agent.
  
  
  CONCLUSIONS
  A high index of suspicion, prompt diagnosis and rapid institution of treatment are essential for a safe outcome following such reactions. To our knowledge, this is the first published report of such a severe reaction to gelofusine infusion that occurs during an orthopaedic procedure.
authors.affiliation: Academic Orthopaedic Unit, Leeds General Infirmary, Leeds School of Medicine, Leeds, LS1 3EX, UK. etsiridis@doctors.org.uk.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Polyzois
authors.forename: Andrina
authors.initials: A
authors.lastname: Lampard
authors.forename: Paras
authors.initials: P
authors.lastname: Mohanlal
authors.forename: Evgenios
authors.initials: E
authors.lastname: Tsiridis
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Manidakis
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Tsiridis