title: Primary neuroendocrine carcinoma of the breast.
abstract: Primary neuroendocrine carcinoma of the breast is rare-only about 30 cases have been reported in literature. Immunohistochemical examination showing expression of chromogranin and/or synaptophysin confirms evidence of neuroendocrine differentiation. Usually foci of neuroendocrine differentiation can be seen in breast carcinoma and are reported to be present in about 2-5% of breast cancer cases. Here, we report a case of breast carcinoma in which most of the areas studied on the tissue section showed neuroendocrine differentiation.
authors.affiliation: Department of Pathology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, UP, India.
authors.forename: Kafil
authors.initials: K
authors.lastname: Akhtar
authors.forename: Sufian
authors.initials: S
authors.lastname: Zaheer
authors.forename: S Shamshad
authors.initials: SS
authors.lastname: Ahmad
authors.forename: M Jaseem
authors.initials: MJ
authors.lastname: Hassan
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology*; D002864:Chromogranins / Q000032:analysis; D005260:Female; D006801:Humans; D016708:Synaptophysin / Q000032:analysis
chemical_list: D002864:Chromogranins; D016708:Synaptophysin