title: An uncommon presenting sign of Langerhans cell histiocytosis: focal perianal lesions without systemic involvement.
abstract: A 3-year-old boy presented with constipation and perianal lesions resembling condyloma latum. The results of a biopsy of the perianal lesions confirmed the diagnosis of Langerhans cell histiocytosis (LCH). Although uncommon, LCH may involve the perianal region. In patients with functional constipation associated with perianal lesions that do not respond to conventional treatment, LCH should be part of the differential diagnosis. A simple biopsy of the external lesion and histologic examination of the mass are essential for diagnosis.
authors.affiliation: Department of Pediatric Surgery, Başkent University Faculty of Medicine, Ankara, Turkey. poguzkurt@yahoo.com
authors.forename: Pelin
authors.initials: P
authors.lastname: Oguzkurt
authors.forename: Faik
authors.initials: F
authors.lastname: Sarialioglu
authors.forename: Semire Serin
authors.initials: SS
authors.lastname: Ezer
authors.forename: Emine
authors.initials: E
authors.lastname: Ince
authors.forename: Fazilet
authors.initials: F
authors.lastname: Kayaselcuk
authors.forename: Akgun
authors.initials: A
authors.lastname: Hicsonmez
mesh_terms: D001004:Anus Diseases / Q000175:diagnosis* / Q000628:therapy; D001706:Biopsy; D002675:Child, Preschool; D017679:Cryotherapy; D003919:Diabetes Insipidus / Q000175:diagnosis; D003937:Diagnosis, Differential; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008297:Male