title: Gas-forming brain abscess caused by Klebsiella pneumoniae.
abstract: Gas forming brain abscess is a rare disease caused by Klebsiella pneumoniae occurring in patients with impaired host defense mechanism such as diabetes mellitus or liver cirrhosis. A 59-year-old man with 2-year history of diabetes mellitus and 20-year history of liver cirrhosis presented to the hospital with headache. On the day after admission, severe headache was developed and he deteriorated rapidly. Brain CT showed a non-enhanced mass including multiple air density as well as surrounding edema seen in the right occipital lobe, and isodensity air-fluid level seen in the right lateral ventricle. Despite emergent ventricular drainage and intraventricular and intravenous administration of antibiotics, his condition progressively worsened to sepsis and to death after 5 days. Bacterial culture of blood and ventricular fluids disclosed a Gram (-) rod, Klebsiella pneumoniae. In this report we review the pathogenic mechanism and its management.
authors.affiliation: Department of Neurosurgery, Dongguk University Ilsan Hospital Seoul, Korea.
authors.forename: Keun Tae
authors.initials: KT
authors.lastname: Cho
authors.forename: Bong Jin
authors.initials: BJ
authors.lastname: Park