title: Concurrent Langerhans cell histiocytosis and nephroblastoma.
abstract: Both Langerhans cell histiocytosis (LCH) and nephroblastoma are rare in children. We report herein the first case of a patient with both diseases concurrently. A 2-year-old female presented with bone pain and swelling of the right humerus. As a result of the local incision biopsy, she was diagnosed as LCH. A nephroblastoma of the left kidney was discovered during her staging work-up. After complete resection of the nephroblastoma, she received standard chemoradiotherapy for nephroblastoma. She is alive without relapse 14 months after initial presentation.
authors.affiliation: Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Narui
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yagasaki
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Asahito
authors.initials: A
authors.lastname: Hama
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Nishio
authors.forename: Hideki
authors.initials: H
authors.lastname: Muramatsu
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Shimoyama
authors.forename: Seiji
authors.initials: S
authors.lastname: Kojima
mesh_terms: D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000150:complications* / Q000000981:diagnostic imaging