title: Patch-test-induced "flare-up" reactions to neomycin at prior biopsy sites.
abstract: "Recall dermatitis" classically refers to the uncommon phenomenon of chemotherapy-induced reactivation of skin damage originally induced by radiotherapy months or years earlier. We compare this condition to ectopic flare-up reactions presenting as dermatitis at existing or previous sites by an inducing agent. Enhanced sensitization of an existent allergen by patch testing is rarely described. We describe a case of a 61-year-old man's developing localized allergic contact dermatitis at previous neomycin-treated sites following the diagnosis of neomycin sensitivity on patch testing, which we attribute to a "flare-up" phenomenon.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of California-San Diego, San Diego, CA, USA.
authors.forename: Sharon E
authors.initials: SE
authors.lastname: Jacob
authors.forename: Chantal
authors.initials: C
authors.lastname: Barland
authors.forename: Mohamed L
authors.initials: ML
authors.lastname: ElSaie
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001706:Biopsy; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D004485:Eczema / Q000139:chemically induced / Q000175:diagnosis; D006801:Humans; D008297:Male; D009355:Neomycin / Q000009:adverse effects*; D010328:Patch Tests / Q000009:adverse effects*; D012867:Skin / Q000276:immunology* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D009355:Neomycin