Usefulness of spectroscopy for biomedical engineering.
Modifications of phenylalanine amino acid after its exposure to near-infrared (NIR) radiation have been investigated using ATRFTIR (Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy). The process of amino acid aggregation after its exposure to NIR has been observed. A possible mechanism of amino acid dimer formation has been proposed with the help of theoretical calculations of quantum mechanics (MP2 and B3LYP/6-31 G* level) using the GAUSSIAN 03 package. The usefulness of spectroscopy for biomedical engineering is discussed. ATR-FTIR appears to be a powerful tool for measuring tissue damage in aqueous environments.
Olsztyńska-Janus
Sylwia
S
Wrocław University of Technology, Institute of Biomedical Engineering and Instrumentation, Wrocław, Poland. Sylwia.Olsztynska-Janus@pwr.wroc.pl
Szymborska
Katarzyna
K
Komorowska
Malgorzata
M
Lipiński
Józef
J
D001698:Biomedical Engineering / Q000379:methods* / Q000706:statistics & numerical data; D019281:Dimerization; D004151:Dipeptides / Q000737:chemistry / Q000528:radiation effects; D066298:In Vitro Techniques; D007259:Infrared Rays; D009842:Oligopeptides / Q000737:chemistry / Q000528:radiation effects; D010649:Phenylalanine / Q000737:chemistry* / Q000528:radiation effects*; D011487:Protein Conformation / Q000528:radiation effects; D011789:Quantum Theory; D012984:Software; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods / Q000706:statistics & numerical data; D019265:Spectroscopy, Near-Infrared / Q000379:methods* / Q000706:statistics & numerical data
D004151:Dipeptides; D009842:Oligopeptides; C002956:alanylalanine; D010649:Phenylalanine