title: [HLA-G alleles and risk of early pregnancy loss].
abstract: BACKGROUND
  To investigate whether HLA-G gene polymorphism is associated with adverse pregnancy outcome, we screened exons 2, 3, 4 of HLA-G gene in 59 women with reproductive failure and 36 fertile women. The HLA-G 10108 allele was more common in the group of examined women than in women from the control group (OR = 5,9; p = 0,09), but this difference was not statistically significant.
  
  
  RESULTS
  We conclude that the HLA-G 10108 allele might influence pregnancy outcome in the Polish population, but further studies are needed in this regard.
authors.affiliation: Klinika Medycyny Matczyno-Płodowej Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1, 72-252 Szczecin.
authors.forename: Olimpia
authors.initials: O
authors.lastname: Sipak-Szmigiel
authors.forename: Cezary
authors.initials: C
authors.lastname: Cybulski
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Ronin-Walknowska
authors.forename: Jan
authors.initials: J
authors.lastname: Lubiński
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics*; D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D011110:Polymorphism, Genetic; D011247:Pregnancy
chemical_list: D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I