title: Abdominal radical trachelectomy: Success and pitfalls in a general gynecologic oncology practice.
abstract: OBJECTIVE
  To report our successes and complications with a series of abdominal radical trachelectomies performed to preserve fertility in young women at the Massachusetts General Hospital (MGH).
  
  
  METHODS
  Institutional review board (IRB) permission was obtained for retrospective record review. Data were collected regarding patient age and parity, tumor stage and histology, surgical time and complications, post-operative complications, follow-up, and pregnancy.
  
  
  RESULTS
  Ten patients underwent radical abdominal trachelectomy, 9 by the same surgeon (LD). Surgery was essentially identical to that of radical hysterectomy with the exception of re-anastomosis of the uterine fundus to the vagina and placement of cerclage. Pre-operative evaluation and post operative follow-up was for the most part identical for all patients. Two patients achieved pregnancy, with 1 twin delivery and 1 patient had 2 pregnancies. Two patients experienced cervical stenosis with regular menses and the same 2 patients passed their abdominal cerclage vaginally. To date there have been no cancer recurrences. Pap smear follow-up has been complicated by difficulty in reading smears from the lower uterine segment (LUS).
  
  
  CONCLUSIONS
  Radical abdominal trachelectomy can be successfully performed by any gynecologic oncologist who is trained in radical pelvic surgery. Pre-operative counseling is crucial in obtaining informed consent. Patients must be aware of potential post-operative complications, including pre-term delivery. Cytology department needs to be aware of potential pitfalls in reading Pap smears from the LUS.
authors.affiliation: Division of Gynecologic Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Olawaiye
authors.forename: Marcela
authors.initials: M
authors.lastname: Del Carmen
authors.forename: Rosemary
authors.initials: R
authors.lastname: Tambouret
authors.forename: Annekathryn
authors.initials: A
authors.lastname: Goodman
authors.forename: Arlan
authors.initials: A
authors.lastname: Fuller
authors.forename: Linda R
authors.initials: LR
authors.lastname: Duska
mesh_terms: D000328:Adult; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D006176:Gynecology / Q000379:methods; D006801:Humans; D008197:Lymph Node Excision; D008495:Medical Oncology / Q000379:methods; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult