Safety and immunogenicity of the Mycobacterium tuberculosis DeltalysA DeltapanCD vaccine in domestic cats infected with feline immunodeficiency virus.
Feline immunodeficiency virus (FIV)-positive and FIV-negative cats (n=4/group) received 2 x 10(6) CFU Mycobacterium tuberculosis DeltalysA DeltapanCD intramuscularly. Vaccination elicited antibody responses, albeit at lower levels in FIV-positive cats than in FIV-negative cats. Delayed-type hypersensitivity responses were minimal in both groups. No adverse reactions were found.
Zimmerman
Dawn M
DM
Memphis Zoo and Aquarium, Memphis, Tennessee 38112, USA. dzimmerman@memphiszoo.org
Waters
W Ray
WR
Lyashchenko
Konstantin P
KP
Nonnecke
Brian J
BJ
Armstrong
Douglas L
DL
Jacobs
William R
WR
Larsen
Michelle H
MH
Egan
Erin
E
Dean
Gregg A
GA
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002415:Cats; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology*; D006968:Hypersensitivity, Delayed; D032581:Tuberculosis Vaccines / Q000009:adverse effects* / Q000276:immunology*
D000907:Antibodies, Bacterial; D032581:Tuberculosis Vaccines