title: Pannus-related prosthetic valve dysfunction and life-threatening aortic regurgitation.
abstract: Prosthetic valve dysfunction is a rare but life-threatening condition. A 66-year-old woman presented with shock 15 years after aortic valve replacement with a tilting-disc valve. Imaging demonstrated severe aortic insufficiency and a fixed-open prosthetic valve. Reoperation revealed pannus ingrowth from the aortic aspect, resulting in immobility of the occluder. A bioprosthetic valve was installed and the patient recovered uneventfully. The diagnosis and surgical management of this problem are discussed.
authors.affiliation: Department of Surgery, Division of Thoracic and Cardiovascular Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: Philip S
authors.initials: PS
authors.lastname: Mullenix
authors.forename: Cyrus J
authors.initials: CJ
authors.lastname: Parsa
authors.forename: G Burkhard
authors.initials: GB
authors.lastname: Mackensen
authors.forename: James G
authors.initials: JG
authors.lastname: Jollis
authors.forename: J Kevin
authors.initials: JK
authors.lastname: Harrison
authors.forename: G Chad
authors.initials: GC
authors.lastname: Hughes
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000473:pathology* / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000601:surgery; D001705:Bioprosthesis; D005260:Female; D005355:Fibrosis; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D011475:Prosthesis Failure; D012086:Reoperation; D012770:Shock, Cardiogenic / Q000209:etiology / Q000601:surgery; D013927:Thrombosis / Q000209:etiology / Q000601:surgery; D014463:Ultrasonography