Cardiac amyloidosis presumptively diagnosed as cardiac syndrome X.
A 75-year-old man with cardiac amyloidosis was presumptively diagnosed as having cardiac syndrome X. Early clinical presentation was repeated episodes of angina pectoris without angiographically significant stenosis of the coronary arteries, so the diagnosis of cardiac syndrome X was initially given. However, his anginal symptoms worsened despite appropriate medication. He developed congestive heart failure and died 8 years after his first anginal symptoms. Autopsy revealed amyloid deposits in the intramyocardial coronary arteries with luminal obstruction, with little in the epicardial coronary arteries or myocardium. Therefore, the definitive diagnosis was cardiac amyloidosis.
Yagishita
Atsuhiko
A
Division of Cardiology, Mitsui Memorial Hospital, 1 Kanda-Izumi-cho, Chiyoda-ku, Tokyo, Japan.
Tanimoto
Shuzou
S
Tanabe
Kengo
K
Isogawa
Akihiro
A
Taniguchi
Makoto
M
Shiba
Teruo
T
Hara
Kazuhiro
K
D000368:Aged; D000682:Amyloid / Q000378:metabolism; D000686:Amyloidosis / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D000787:Angina Pectoris / Q000175:diagnosis / Q000209:etiology; D003331:Coronary Vessels / Q000378:metabolism / Q000473:pathology; D003937:Diagnosis, Differential; D006331:Heart Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008297:Male; D017566:Microvascular Angina / Q000150:complications / Q000175:diagnosis*
D000682:Amyloid