title: A case of maternal herpes simplex virus encephalitis during late pregnancy.
abstract: BACKGROUND
  A pregnant 25-year-old woman at 32 weeks' gestation was admitted to an emergency unit after her husband had found her drowsy and with her tongue bitten. The day before admission, the patient had developed a fever of 39 degrees C, was suffering from headaches, was nauseated and had vomited. On admission, she had anterograde and retrograde amnesia, but no somatic neurological deficits were detected.
  
  
  METHODS
  Routine laboratory testing, lumbar puncture, cerebrospinal fluid analysis, routine bacteriology, brain MRI, and polymerase chain reaction testing for neurotropic viruses including herpes simplex virus types 1 and 2.
  
  
  METHODS
  Maternal herpes simplex virus type 1 encephalitis.
  
  
  RESULTS
  Antiviral and anticonvulsive therapy, supportive treatment, and cesarean section.
authors.affiliation: Department of Neurology, Klinikum rechts der Isar at the Technical University of Munich, Munich, Germany.
authors.forename: Johann
authors.initials: J
authors.lastname: Sellner
authors.forename: Roberto
authors.initials: R
authors.lastname: Buonomano
authors.forename: Krassen
authors.initials: K
authors.lastname: Nedeltchev
authors.forename: Oliver
authors.initials: O
authors.lastname: Findling
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schroth
authors.forename: Daniel V
authors.initials: DV
authors.lastname: Surbek
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Leib
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology / Q000821:virology; D020803:Encephalitis, Herpes Simplex / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D018259:Herpesvirus 1, Human; D006801:Humans; D000077213:Lamotrigine; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000503:physiopathology* / Q000821:virology*; D012640:Seizures / Q000517:prevention & control / Q000821:virology; D014227:Triazines / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D000998:Antiviral Agents; D014227:Triazines; D000077213:Lamotrigine; D000212:Acyclovir