Effect of modifications of dual acid-etched implant surfaces on periimplant bone formation. Part II: calcium phosphate coatings.
The aim of the present study was to test the hypothesis that calcium phosphate coatings of dual acid-etched surfaces (DAEs) can improve periimplant bone regeneration. Ten adult female foxhounds received experimental titanium screw implants in the mandible 3 months after removal of all premolar teeth. Five types of surface states were evaluated in each animal: (i) implants with a machined surface (MS) (Control 1); (ii) implants with a DAE (Control 2); (iii) implants with a DAE coated with collagen I (Control 3); (iv) implants with a DAE with mineralized collagen I; and (v) implants with a DAE with a hydroxylapatite (HA) coating. Periimplant bone regeneration was assessed by histomorphometry after 1 and 3 months in five dogs each by measuring bone implant contact (BIC) and the volume density of the newly formed periimplant bone (BVD). After 1 month, mean BIC of experimental implants did not differ significantly from implants with DAE and collagen-coated surfaces, but was significantly higher than the MS implants. BVD was enhanced significantly only in implants with mineralized collagen coating compared with DAE and collagen-coated controls. After 3 months, the mean values of BIC had increased significantly in the group of implants with HA and mineralized collagen coating but were not significantly different from implants with DAE and collagen-coated surfaces. The same held true for the mean BVD values. In conclusion, the present study could not verify the hypothesis that calcium phosphate coatings of DAEs in the present form enhanced periimplant bone formation compared with the DAE surface alone.
Schliephake
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H
Department of Oral and Maxillofacial Surgery, George-Augusta-University, Göttingen, Germany. schliephake.henning@med.uni-goettingen.de
Aref
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A
Scharnweber
D
D
Rösler
S
S
Sewing
A
A
D000134:Acid Etching, Dental; D000818:Animals; D015519:Bone Density; D002448:Cell Adhesion; D020099:Coated Materials, Biocompatible; D024042:Collagen Type I / Q000494:pharmacology*; D015921:Dental Implants; D004285:Dogs; D017886:Durapatite / Q000494:pharmacology*; D005260:Female; D006801:Humans; D020007:Implants, Experimental; D016348:Osseointegration / Q000187:drug effects*; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium
D020099:Coated Materials, Biocompatible; D024042:Collagen Type I; D015921:Dental Implants; D017886:Durapatite; D014025:Titanium