Iridium-catalyzed asymmetric hydrogenation of cyclic enamines.
The first highly enantioselective iridium-catalyzed hydrogenation of cyclic enamines has been developed. This new reaction provided an efficient method for the synthesis of optically active cyclic tertiary amines including natural product crispine A.
Hou
Guo-Hua
GH
State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
Xie
Jian-Hua
JH
Yan
Pu-Cha
PC
Zhou
Qi-Lin
QL