title: Validity and reliability of the Portuguese-Brazilian version of the Quality of Life in Epilepsy Inventory-89.
abstract: OBJECTIVE
  The purpose of this article was to report the translation of the Quality of Life in Epilepsy Inventory-89 (QOLIE-89) into a Portuguese-Brazilian version and evaluate its reliability and validity.
  
  
  METHODS
  This study involved 105 outpatients: 54 patients with refractory temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and 51 with juvenile myoclonic epilepsy (JME). Reliability and test-retest reliability were assessed. Relationships between QOLIE-89 domains and other questionnaires (Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, Neuropsychological Evaluation), and external measures such as demographic and clinical variables were analyzed to examine construct validity.
  
  
  RESULTS
  Internal consistency (Cronbach's alpha=0.73-0.92) and test-retest reliability (intraclass correlation coefficient=0.60-0.84) for individual domains were acceptable. For construct validity, we verified high correlations between the QOLIE-89 and the Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, and Neuropsychological Evaluation. For clinical characteristics, the patients with juvenile myoclonic epilepsy had better quality-of-life scores on 11 of 17 QOLIE-89 subscales compared with patients with temporal lobe epilepsy (P<0.05).
  
  
  CONCLUSIONS
  These results support the reliability and validity of the Portuguese-Brazilian translation of QOLIE-89.
authors.affiliation: Department of Neurology, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Auro Mauro
authors.initials: AM
authors.lastname: Azevedo
authors.forename: Neide Barreira
authors.initials: NB
authors.lastname: Alonso
authors.forename: Marcos
authors.initials: M
authors.lastname: Vidal-Dourado
authors.forename: Maria Helena da Silva
authors.initials: MH
authors.lastname: Noffs
authors.forename: Tatiana Frascarelli
authors.initials: TF
authors.lastname: Pascalicchio
authors.forename: Luís Otávio Sales Ferreira
authors.initials: LO
authors.lastname: Caboclo
authors.forename: Rozana Mesquita
authors.initials: RM
authors.lastname: Ciconelli
authors.forename: Américo Ceiki
authors.initials: AC
authors.lastname: Sakamoto
authors.forename: Elza Márcia Targas
authors.initials: EM
authors.lastname: Yacubian
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D001938:Brazil; D003071:Cognition / Q000502:physiology; D003863:Depression / Q000209:etiology / Q000523:psychology; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology* / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000523:psychology; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D020190:Myoclonic Epilepsy, Juvenile / Q000523:psychology; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures; D011174:Portugal; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D015203:Reproducibility of Results; D012640:Seizures / Q000453:epidemiology; D012934:Social Isolation; D012944:Social Support; D012959:Socioeconomic Factors
chemical_list: D000927:Anticonvulsants