Abnormal FDG uptake on 18F-fluorodeoxyglucose positron emission tomography in patients with cancer diagnosis: case reports of tuberculous lymphadenitis.
Although 18F-FDG-PET is very sensitive for a variety of malignancies, it can lack specificity. In addition to malignant tissue, any active infectious or inflammatory process can demonstrate FDG avidity. We report 3 patients with different types of cancer who had abnormal 18F-FDG uptake on PET scan caused by tuberculous lymphadenitis. All were found to have incidental multiple lymph adenopathies with increased FDG uptake on PET scan. All three patients were proved to have tuberculosis lymphadenitis by pathologic examination and were successfully treated with anti-tuberculous therapy.
Ataergin
Selmin
S
Department of Medical Oncology, GATA (Gulhane) Faculty of Medicine, Ankara, Turkey. sataergin@superonline.com
Arslan
Nuri
N
Ozet
Ahmet
A
Ozguven
M Ali
MA
D000995:Antitubercular Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications / Q000000981:diagnostic imaging; D003110:Colonic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008223:Lymphoma / Q000150:complications / Q000000981:diagnostic imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D009369:Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000150:complications / Q000000981:diagnostic imaging; D014388:Tuberculosis, Lymph Node / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000188:drug therapy
D000995:Antitubercular Agents; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18