Hepatic veno-occlusive disease and human herpes virus 7 infection in primary agammaglobulinemia.
Hepatobiliary disease has been described in Bruton's x-linked agammaglobulinemia; however, veno-occlusive disease has not been reported in this setting. We report a case of end-stage liver disease in a patient with x-linked agammaglobulinemia who was found to have VOD and evidence of human herpes virus 7 infection in the explanted liver after transplantation.
Soden
Jason S
JS
Pediatric Liver Center and Liver Transplantation Program, Department of Pediatrics, University of Colorado Denver School of Medicine, and The Children's Hospital, Aurora, CO 80045, USA. soden.jason@tchden.org
Narkewicz
Michael R
MR
Haas
Joel E
JE
Sokol
Ronald J
RJ
D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications* / Q000188:drug therapy; D004279:DNA, Viral / Q000097:blood; D006504:Hepatic Veno-Occlusive Disease / Q000150:complications* / Q000601:surgery; D016199:Herpesvirus 7, Human / Q000235:genetics; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008099:Liver / Q000473:pathology; D017093:Liver Failure / Q000209:etiology*; D016031:Liver Transplantation; D008297:Male; D019349:Roseolovirus Infections / Q000150:complications / Q000175:diagnosis*
D004279:DNA, Viral; D016756:Immunoglobulins, Intravenous