[Relationship of genetic polymorphism of PRLR and RBP4 genes with litter size traits in pig].
The polymorphism of prolactin receptor (PRLR) and retinol-binding protein 4 (RBP4) genes was detected by PCR-RFLP method, and the effects of PRLR and RBP4 genes on litter size traits in pig were analyzed by the least square analysis. Data of total number born (TNB) and number born alive (NBA) from 323 sows, including five Shandong local pig breeds and three foreign pig breeds, were collected. The results showed that the polymorphic sites of both PRLR and RBP4 genes were found in all populations tested. The genotype distribution, however, revealed great differences between Shandong local pig breeds and foreign pig breeds. The effects of genotypes on TNB and NBA were significant (P<0.05). The homozygote AA was the most prolific genotype. For PRLR gene, AA genotypic sows of Shandong local pig breeds and foreign pig breeds produced 1.03 TNB, 0.89 NBA, and 1.26 TNB, 1.11 NBA more than BB genotypic sows, respectively. For RBP4 gene, AA genotypic sows of Shandong local pig breeds and foreign pig breeds produced 0.59 TNB, 0.51 NBA and 0.72 TNB, 0.64 NBA more than BB genotypic sows, respectively.
Sun
Yan-Xiao
YX
College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. yxsun@sdau.edu.cn
Zeng
Yong-Qing
YQ
Tang
Hui
H
Fan
Xin-Zhong
XZ
Chen
Qi-Mei
QM
Li
Hua
H
Qian
Yuan
Y
Song
Yi-Ping
YP
D000818:Animals; D005838:Genotype; D008098:Litter Size / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011981:Receptors, Prolactin / Q000235:genetics*; D054839:Retinol-Binding Proteins, Plasma / Q000235:genetics*; D013552:Swine
D011981:Receptors, Prolactin; D054839:Retinol-Binding Proteins, Plasma