Malignant acoustic schwannoma in a dog.
A malignant schwannoma of the right acoustic nerve of a dog is described. The neoplasm was found during necropsy of a 12-year-old, spayed, female Labrador Retriever that experienced a sudden onset of severe pain in the neck and upon opening the mouth. Concurrent mild hind limb ataxia also was present. The tumor had infiltrative growth, and the spindle-shaped neoplastic cells were arranged in sheets and concentric whorls. Immunohistochemical staining of the neoplastic spindle cells was positive for S-100 antigen, neuron-specific enolase, and glial fibrillary acidic protein.
Ottinger
Therese
T
Department of Biomedical Sciences and Veterinary Public Health, Division of Pathology, Swedish University of Agricultural Sciences, Uppsala, Sweden. therese.ottinger@bvf.slu.se
Lindberg
Ronny
R
Ekman
Stina
S
D000818:Animals; D003056:Cochlear Nerve / Q000473:pathology; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D009464:Neuroma, Acoustic / Q000473:pathology / Q000662:veterinary*