title: A problem solving in driving tests which method for carbohydratedeficient transferrin (cdt) in adolescents affected by celiac disease?
abstract: This study aimed at evaluating the relationships among pathologies and methods employed to detect transglutaminase (tTG) and carbohydrate-deficient transferrin (CDT) in 33 celiac subjects presenting either high or low levels of tTG. Elevated tTG values were associated with increased CDT levels. A significant correlation was found between CDT and tTG values (r=0.57; p>0.0001). In the absence of wider studies and assessments on the interferences between methods used for these dosages and in presence of pathologies as carbohydrate-deficient glycoprotein syndrome (CDGs), this account assumes a possible correlation with celiac disease and suggests that the CDT test should not be used in celiac patients to authorize the return of the driving license after its withdrawal due to alcohol abuse [1, 2, 3].
authors.affiliation: Department of Laboratory Medicine, IRCCS Burlo Garofolo, Children's Hospital, Via dell'Istria, Trieste, Italy, UE.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Tamaro
authors.forename: Sandra
authors.initials: S
authors.lastname: Perticarari
authors.forename: Tanja
authors.initials: T
authors.lastname: Princi
authors.forename: Agostino
authors.initials: A
authors.lastname: Accardo
authors.forename: Michela
authors.initials: M
authors.lastname: Donato
authors.forename: Fulvia
authors.initials: F
authors.lastname: Vascotto
authors.forename: Sergio
authors.initials: S
authors.lastname: Parco