EUS-assisted band ligation of small duodenal stromal tumors and follow-up by EUS.
BACKGROUND
Duodenal GI stromal tumors (GISTs), with potential for malignant transformation, arise in muscularis propria. It is difficult to endoscopically resect lesions in the muscularis propria by using standard electrosurgical techniques.


OBJECTIVE
Our purpose was to investigate the efficacy of a new method for resection of these tumors, EUS-assisted band ligation.


METHODS
Prospective study.


METHODS
Shenjing Hospital of China Medical University.


METHODS
Nineteen elderly or high surgical risk patients with small duodenal GISTs.


METHODS
A standard endoscope with a transparent cap attached to the tip was used. The cap was placed over the lesion, maximum sustained suction was applied, and an elastic band was released around the base. EUS was used to determine whether the hypoechoic mass was confined completely by the band.


METHODS
Beginning 2 weeks after banding, the lesions were observed endoscopically once per week until healing was complete. Thereafter, all patients underwent EUS every 2 to 3 months on schedule.


RESULTS
The tumors sloughed completely. The mean time required for complete healing after band ligation was 4.7 weeks. Bleeding occurred in 2 patients 7 days after ligation because the lesion sloughed. The bleeding was self-limiting and not life threatening. No perforation or other complications occurred. Follow-up ranged from 18 to 63 months, during which time no recurrence was observed.


CONCLUSIONS
New technique with limited data.


CONCLUSIONS
EUS-assisted band ligation with systematic follow-up by EUS is an effective and safe treatment for small duodenal GISTs.
Sun
Siyu
S
Endoscopy Center, Shengjing Hospital, China Medical University, Shenyang, China. sunsy@cmu2h.com
Ge
Nan
N
Wang
Sheng
S
Liu
Xiang
X
Lü
Qingjie
Q
D000328:Adult; D000368:Aged; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D019160:Endosonography; D005260:Female; D005500:Follow-Up Studies; D046152:Gastrointestinal Stromal Tumors / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008026:Ligation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies