Resins with identical specifications are not identical. Identifying a useful solid-phase resin.
The quality of the most commonly used support for solid-phase syntheses, polystyrene resin cross-linked with 1% of divinylbenzene, differs considerably even among different lots of resin from the same source. Determination of the swelling capacity of resins before carrying out solid-phase syntheses represents a very simple means of nondestructive presynthetic resin characterization.
Bouillon
Isabelle
I
Department of Chemistry and Biochemistry, 251 Nieuwland Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Soural
Miroslav
M
Miller
Marvin J
MJ
Krchnák
Viktor
V
D020650:Combinatorial Chemistry Techniques; D003432:Cross-Linking Reagents / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry*; D012117:Resins, Synthetic / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
D003432:Cross-Linking Reagents; D011137:Polystyrenes; D012117:Resins, Synthetic; D014753:Vinyl Compounds; C004985:divinyl benzene