Chanarin-Dorfman syndrome with eccrine gland vacuolation: a case report.
Chanarin-Dorfman syndrome is a rare congenital disorder of lipid metabolism characterized by ichthyosis, leukocytic vacuolation (Jordan's anomaly), and variable involvement of the liver and neuromuscular system, with about 40 cases described worldwide to date. We report one more case of this rare syndrome, with certain peculiarities, namely vacuolation in eccrine glands, in a young male adult.
Pahwa
Manish
M
Dermatology Department, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. manubee0@yahoo.co.in
Kar
Rakhee
R
Singh
Avninder
A
Goel
Alka
A
Ramesh
V
V
Jain
Rakesh
R
D000328:Adult; D004439:Eccrine Glands / Q000473:pathology*; D004483:Ectropion; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000473:pathology; D008052:Lipid Metabolism, Inborn Errors / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology; D013577:Syndrome; D014617:Vacuoles / Q000473:pathology*