title: Time to testing and accessing care among a population of newly diagnosed patients with HIV with a high proportion of Canadian Aboriginals, 1998-2003.
abstract: Early HIV diagnosis and treatment are important for decreasing HIV transmission and morbidity. By using initial CD4 counts and time to first viral load test, we examined the stage of disease at the time of diagnosis and the time to accessing medical care after diagnosis, respectively. Initial CD4 count, first HIV viral load test, demographics and exposure risks were obtained for all newly diagnosed HIV cases in Northern Alberta from 1998-2003. Time to accessing care was determined as the time between diagnosis and the first viral load test. Correlates were determined using simple descriptive statistics and survival analysis methods. Of 526 HIV cases, median age was 36 years (interquartile range [IQR]: 31-43), 69% were males and 41% were Aboriginal. At diagnosis, 28% of the population had CD4 counts less than 200 cells=mm3. After diagnosis, 92.2% accessed care and median time to care for the entire population was 29 days. In multivariate analysis, age at diagnosis less than 45 years was independently associated with longer median time to care (versus age 45 years or more; adjusted hazard ratio [AHR]: 0.69; 95% confidence interval [CI] 0.55-0.88), while Aboriginal ethnicity (versus Caucasian; AHR: 0.82; 95% CI 0.68-1.01), and nonmetropolitan residence (versus metropolitan; AHR: 0.81; 95% CI 0.65-1.00) were marginally significant correlates for longer times to care. Although more than one quarter of cases were diagnosed at relatively advanced stages of infection, the majority of new HIV cases in Northern Alberta accessed care within 2 months of diagnosis. We need to explore new strategies to facilitate and promote earlier access to testing among individuals at risk.
authors.affiliation: Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Canada.
authors.forename: Sabrina S
authors.initials: SS
authors.lastname: Plitt
authors.forename: Dana
authors.initials: D
authors.lastname: Mihalicz
authors.forename: Ameeta E
authors.initials: AE
authors.lastname: Singh
authors.forename: Gayatri
authors.initials: G
authors.lastname: Jayaraman
authors.forename: Stan
authors.initials: S
authors.lastname: Houston
authors.forename: Bonita E
authors.initials: BE
authors.lastname: Lee
mesh_terms: D015492:AIDS Serodiagnosis; D000328:Adult; D000416:Alberta; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000208:ethnology* / Q000821:virology; D015497:HIV-1 / Q000276:immunology / Q000302:isolation & purification; D006297:Health Services Accessibility; D006801:Humans; D007198:Indians, North American; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D018570:Risk Assessment; D016019:Survival Analysis; D013997:Time Factors; D019562:Viral Load; D044465:White People