Effect of monovalent ion adsorption on the electric charge of phosphatidylcholine - decylamine liposomal membranes.
We examined the effect of adsorbed monovalent ions on the surface charge of phosphatidylcholine (PC) - decylamine (DA) liposomal membranes. Surface charge density values were determined from electrophoretic mobility measurements of lipid vesicles performed at various pH levels. The interaction between solution ions and the PC-DA liposomal surface was described by a six component equilibrium model. The previously determined association constants of the -PO((-)) and -N((+))(CH(3))(3) groups of PC with H(+), OH(-), Na(+) and Cl(-) ions (K (A1H), K (B1OH), K (A1Na), K (B1C1)) were used to calculate K (B2OH), and K (B2C1), the association constants of the -N((+))H(3) group of DA with OH(-) and Cl(-) ions, providing an experimental verification for the proposed model.
Kotyńska
Joanna
J
Institute of Chemistry, University of Bialystok, Al. Pilsudskiego 11/4, 15-443, Bialystok, Poland.
Dobrzyńska
Izabela
I
Figaszewski
Zbigniew Artur
ZA
D000327:Adsorption; D000588:Amines / Q000737:chemistry*; D003198:Computer Simulation; D007477:Ions; D008051:Lipid Bilayers / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D008564:Membrane Potentials; D008956:Models, Chemical; D010713:Phosphatidylcholines / Q000737:chemistry*; D055672:Static Electricity
D000588:Amines; D007477:Ions; D008051:Lipid Bilayers; D008081:Liposomes; D010713:Phosphatidylcholines; C004744:decylamine