title: Recurrent liver hydatid disease: when does it become symptomatic and how does one diagnose it?
abstract: BACKGROUND
  Echinococcosis is a zoonotic disease that mainly occurs in sheep-grazing areas. Recurrence of the disease and its diagnosis are relatively new areas of investigation due to the limited number of cases. The aim of this study was to evaluate the diagnosis of the symptomatic recurrent liver hydatid disease and the efficacy of abdominal ultrasonography (US).
  
  
  METHODS
  Between 1988 and 2006, 412 patients with hydatid cyst of the liver were operated at Erciyes University Medical Faculty. We have considered a growing cyst at the original operative site or at the neighboring hepatic tissue as recurrence and investigated 38 of them for the recurrence of the disease (9.2%).
  
  
  RESULTS
  The recurrence usually occurred after 2 years. The majority of the cases were Types 2 and 3 (24 cases; 8 were Type 4 and 6 were Type 1) according to Gharbi classification. In 35 patients with recurrent disease approved after surgical exploration, US was successful in preoperative diagnosis (100%). Overall, the recurrence was demonstrated correctly by means of US in 35 patients (92.1%), and 23 of 26 patients (88.4%) were correctly diagnosed with the use of computed tomography. In our study, in the first 2 years after the operation, the success rate of US examination was 72.7%. The success rate of US rose up to 100% when the frequency of recurrence is highest.
  
  
  CONCLUSIONS
  Beyond 2 years after surgery, US examination alone might be enough for the diagnosis of symptomatic recurrent liver hydatid disease in patients with the suspicion of recurrence. Postoperative early US profile and annual US examination must be performed for at least 5 years to prevent misinterpretation in doubtful cases.
authors.affiliation: Department of General Surgery, Erciyes University School of Medicine, Kayseri, Turkey. hyakyildiz@gmail.com
authors.forename: Hiizir Yakup
authors.initials: HY
authors.lastname: Akyildiz
authors.forename: Alper
authors.initials: A
authors.lastname: Akcan
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Karahan
authors.forename: Can
authors.initials: C
authors.lastname: Kucuk
authors.forename: Erdogan
authors.initials: E
authors.lastname: Sözüer
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Esin
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D012008:Recurrence; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014421:Turkey / Q000453:epidemiology; D014463:Ultrasonography / Q000706:statistics & numerical data*