title: Effector and memory CD4+ and CD8+ T cells in the chronic infection process.
abstract: T cell memory in comparison with B cell memory is not well understood. This review focuses on CD8+ and CD4+ memory T cells. In this article we try to define memory cells and also present models of memory T cells formation. We would also like to delineate their differentiation into distinct subsets. Long-lived memory T cells consist in two main subsets: TCM and TEM. Recent studies have shown that not all cells considered to be memory cells differentiate into TCM and TEM, but a small proportion of theses cells exhibit naive cells phenotype. Memory T cells constitute a heterogeneous population of cells. In this study we lay stress on characteristic of main memory T cells subsets and their alleged participation in immune response upon reexposure to the Ag.
authors.affiliation: Department of Microbiological Diagnostics, Medical University of Bialystok, Poland.
authors.forename: Dominika
authors.initials: D
authors.lastname: Ojdana
authors.forename: Kamil
authors.initials: K
authors.lastname: Safiejko
authors.forename: Alina
authors.initials: A
authors.lastname: Lipska
authors.forename: Piotr
authors.initials: P
authors.lastname: Radziwon
authors.forename: Jacek
authors.initials: J
authors.lastname: Dadan
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Tryniszewska
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D002908:Chronic Disease; D006801:Humans; D007156:Immunologic Memory / Q000276:immunology*; D007239:Infections / Q000276:immunology*; D018448:Models, Immunological