title: Fertility rate of epileptic women at Kenyatta National Hospital.
abstract: BACKGROUND
  Reproductive health issues of women with epilepsy (WWE) are complex and multifaceted, and both epilepsy and antiepileptic drug (AEDs) use may alter fertility and pregnancy outcomes in these women.
  
  
  OBJECTIVE
  To determine the fertility rate of women with epilepsy at Kenyatta National Hospital (KNH).
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Neurology clinic, KNH, Nairobi, Kenya, between October 2006 and March 2007.
  
  
  METHODS
  A total of 191 women with epilepsy (aged 15-49 years) who had been epileptic for at least one year were interviewed regarding their pregnancy and birth histories, and the information validated with medical records where available.
  
  
  RESULTS
  The general fertility rate (GFR) for reproductive-aged epileptic women for the three-year period (2003-2006) preceding the study was 46 livebirths per 1000 women-years (95% CI 35.13-63.59).
  
  
  CONCLUSIONS
  Fertility rate in epileptic women is decreased by two thirds (compared to that of general population of women in Kenya). Reasons for this are probably miltifactorial.
authors.affiliation: Department of Clinical Medicine and Therapeutics, College of Health Sciences, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya.
authors.forename: J G
authors.initials: JG
authors.lastname: Kariuki
authors.forename: M D
authors.initials: MD
authors.lastname: Joshi
authors.forename: A M
authors.initials: AM
authors.lastname: Adam
authors.forename: T O O
authors.initials: TO
authors.lastname: Kwasa
authors.forename: M
authors.initials: M
authors.lastname: Machoki
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D004827:Epilepsy / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005298:Fertility / Q000187:drug effects*; D006306:Health Surveys; D006801:Humans; D007407:Interviews as Topic; D007630:Kenya; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D055815:Young Adult
chemical_list: D000927:Anticonvulsants