title: Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles.
abstract: Doped up: The incorporation of Zn(2+) dopants in tetrahedral sites leads to the successful magnetism tuning of spinel metal ferrite nanoparticles (see picture). (Zn(0.4)Mn(0.6))Fe(2)O(4) nanoparticles exhibit the highest magnetization value among the metal ferrite nanoparticles. Such high magnetism results in the largest MRI contrast effects (r2=860 mm(-1) s(-1)) reported to date and also huge hyperthermic effects.
authors.affiliation: Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Jung-tak
authors.initials: JT
authors.lastname: Jang
authors.forename: Hyunsoo
authors.initials: H
authors.lastname: Nah
authors.forename: Jae-Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Seung Ho
authors.initials: SH
authors.lastname: Moon
authors.forename: Min Gyu
authors.initials: MG
authors.lastname: Kim
authors.forename: Jinwoo
authors.initials: J
authors.lastname: Cheon
mesh_terms: D016923:Cell Death; D003287:Contrast Media / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D005334:Fever / Q000139:chemically induced*; D006367:HeLa Cells; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use / Q000648:ultrastructure; D015032:Zinc / Q000737:chemistry
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; C001215:ferrite; D015032:Zinc