More images that yet fresh images Beget.
In this issue of Immunity, Dong et al. (2009) describe the protein crystal structure heterodimer of tapasin and ERp57, which helps visualize the function of these proteins in loading of peptide antigens onto MHC class I molecules as part of the peptide loading complex within the endoplasmic reticulum.
Elliott
Tim
T
Cancer Sciences Division, School of Medicine, University of Southampton, Southampton, UK.
D004721:Endoplasmic Reticulum / Q000502:physiology*; D015395:Histocompatibility Antigens Class I / Q000276:immunology*; D006801:Humans; D026901:Membrane Transport Proteins / Q000737:chemistry* / Q000502:physiology; D008954:Models, Biological; D046912:Multiprotein Complexes / Q000737:chemistry; D010455:Peptides / Q000502:physiology*; D019704:Protein Disulfide-Isomerases / Q000737:chemistry*
D015395:Histocompatibility Antigens Class I; D026901:Membrane Transport Proteins; D046912:Multiprotein Complexes; D010455:Peptides; C107762:tapasin; D019704:Protein Disulfide-Isomerases; C085868:PDIA3 protein, human