[Disturbance of the radial system of interphase microtubules in the presence of excess serum in cell culture medium].
The role of the orderliness of microtubules in the cell has been studied. For this purpose, a population of Vero cells with chaotically arranged microtubules was used, which was obtained after the addition of excess serum to cell culture medium. An increase in the total area and a slight dispersion of the Golgi apparatus were found; however, the rate of culture growth as a whole remained normal. Thus, the radial arrangement of microtubules is not vital even for cells where it is usually well pronounced.
Usova
E V
EV
Burakov
A V
AV
Spil'man
A A
AA
Nadezhdina
E S
ES
D000818:Animals; D002417:Cattle; D018929:Cell Culture Techniques; D002522:Chlorocebus aethiops; D003470:Culture Media; D038362:Glycogen Synthase Kinase 3 / Q000378:metabolism; D000071679:Glycogen Synthase Kinase 3 beta; D006056:Golgi Apparatus / Q000648:ultrastructure; D007399:Interphase; D008870:Microtubules / Q000648:ultrastructure*; D044967:Serum; D014709:Vero Cells
D003470:Culture Media; D000071679:Glycogen Synthase Kinase 3 beta; D038362:Glycogen Synthase Kinase 3