Angio-Seal use in patients with peripheral arterial disease (ASPIRE).
OBJECTIVE
To investigate the incidence of complications after the use of an arterial closure device (Angio-Seal) in patients with peripheral arterial disease.


METHODS
In 105 consecutive patients after transfemoral catheterization, the puncture site was closed using a closure device (Angio-Seal). Colour-flow-duplexsonography studies were conducted 1 to 4 days before, within 3 days after and 3 month after the intervention.


RESULTS
All patients had peripheral arterial disease, 34 had calcification at the puncture site. Detection of calcification did not prevent device deployment. Complications (2 minor bleedings, 1 pseudoaneurysm) were not associated with high risk groups (these were: 69 antegrade punctures, 22 obese and 32 hypertensive patients). Three-month postinterventional diameter and blood velocity changes were <1%.


CONCLUSIONS
Patients with peripheral arterial disease in the region of the puncture site and patients at higher complication risk can safely and effectively be closed with an Angio-Seal device. At the puncture site, no lumen change can be observed 3 months postinterventional.
Katzenschlager
Reinhold
R
Department of Angiology, Hanusch Hospital, Vienna, Austria. Reinhold.katzenschlager@wgkk.sozvers.at
Tischler
Reinhold
R
Kalchhauser
Georg
G
Panny
Michael
M
Hirschl
Mirko
M
D017541:Aneurysm, False / Q000209:etiology; D001783:Blood Flow Velocity; D002114:Calcinosis / Q000150:complications; D002406:Catheterization, Peripheral / Q000009:adverse effects*; D004867:Equipment Design; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006489:Hemostatic Techniques / Q000009:adverse effects / Q000295:instrumentation*; D006801:Humans; D006973:Hypertension / Q000150:complications; D017078:Laser-Doppler Flowmetry; D008297:Male; D009765:Obesity / Q000150:complications; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D011677:Punctures; D011859:Radiography; D012039:Regional Blood Flow; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color