title: Early treatment of a quetiapine and sertraline overdose with Intralipid.
abstract: We describe the initial management and subsequent recovery of a 61 year-old male patient following attempted suicide by oral ingestion of a potentially fatal overdose of quetiapine and sertraline. Intravenous Intralipid was given soon after initiation of basic resuscitation. There was a rapid improvement in the patient's level of consciousness. No other clinical signs of drug toxicity were observed. Intralipid may have reversed the deep coma associated with ingestion and prevented other manifestations of drug toxicity occurring, thus expediting this patient's recovery.
authors.affiliation: Department of Anaesthesia, Worthing Hospital, Worthing, UK.
authors.forename: S D H
authors.initials: SD
authors.lastname: Finn
authors.forename: D R
authors.initials: DR
authors.lastname: Uncles
authors.forename: J
authors.initials: J
authors.lastname: Willers
authors.forename: N
authors.initials: N
authors.lastname: Sable
mesh_terms: D000928:Antidepressive Agents / Q000506:poisoning; D014150:Antipsychotic Agents / Q000506:poisoning; D003128:Coma / Q000139:chemically induced / Q000628:therapy; D003987:Dibenzothiazepines / Q000506:poisoning*; D062787:Drug Overdose / Q000628:therapy; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069348:Quetiapine Fumarate; D020280:Sertraline / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D005217:Fat Emulsions, Intravenous; D000069348:Quetiapine Fumarate; D020280:Sertraline