Clinical management of HIV/hepatitis C virus coinfection.
OBJECTIVE
The purpose of this study was to review the current management of hepatitis C virus (HCV) in persons coinfected with HIV.


METHODS
Comprehensive review of current scientific literature derived from electronic databases, article bibliographies, and conference abstracts.


CONCLUSIONS
HCV treatment is feasible in the individual coinfected with HIV; however, therapy is complex and requires intensive monitoring and support to achieve the outcome of viral eradication. New strategies to improve HCV treatment rates, adherence to therapy, and virological response rates are needed in this patient population.


CONCLUSIONS
Nurse practitioners are crucial to the management of the HIV/HCV-coinfected patient. This patient population requires detailed clinical monitoring, education, side effect management, and strategies to improve adherence to therapy.
Pozza
Renee
R
Southern California Liver Centers, San Clemente, California, USA. rpozza@apu.edu
D023241:Antiretroviral Therapy, Highly Active; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D015897:Comorbidity; D018450:Disease Progression; D016903:Drug Monitoring; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000451:nursing; D006301:Health Services Needs and Demand; D006526:Hepatitis C / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000451:nursing; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008103:Liver Cirrhosis / Q000821:virology; D055118:Medication Adherence; D009722:Nurse Practitioners; D024802:Nurse's Role; D012254:Ribavirin / Q000627:therapeutic use; D012307:Risk Factors; D012720:Severity of Illness Index; D012944:Social Support
D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons