Chronic organophosphate (OP)-induced neuropsychiatric disorder is a withdrawal syndrome.
Chronic organophosphate-induced neuropsychiatric disorder is a less well-characterized syndrome, which is usually delay-occurred, persists long and is similar to the symptom of cholinergic deficit, its mechanism is unclear. The characteristics of chronic organophosphate-induced neuropsychiatric disorder are somewhat opposite to the direct action of OP pesticide, since withdrawal effect is usually opposite to the original effect of a drug, hypothesis that chronic organophosphate-induced neuropsychiatric disorder is a kind of withdrawal syndrome is suggested.
Tan
De-Hong
DH
Evaluation and Research Center for Toxicology, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, 20 Dong Da Jie Street, Fengtai District, Beijing 100071, PR China. tandehongsy@126.com
Peng
Shuang-Qing
SQ
Wu
Ying-Liang
YL
Wang
Yi-Mei
YM
Lu
Chun-Feng
CF
Yan
Chang-Hui
CH
D006801:Humans; D001523:Mental Disorders / Q000139:chemically induced*; D009943:Organophosphorus Compounds / Q000633:toxicity*; D013375:Substance Withdrawal Syndrome
D009943:Organophosphorus Compounds