The concordance correlation coefficient for repeated measures estimated by variance components.
The concordance correlation coefficient (CCC) is an index that is commonly used to assess the degree of agreement between observers on measuring a continuous characteristic. Here, a CCC for longitudinal repeated measurements is developed through the appropriate specification of the intraclass correlation coefficient from a variance components linear mixed model. A case example and the results of a simulation study are provided.
Carrasco
Josep L
JL
Biostatistics, Department of Public Health, University of Barcelona, Barcelona, Spain. jlcarrasco@ub.edu
King
Tonya S
TS
Chinchilli
Vernon M
VM
D000465:Algorithms; D000704:Analysis of Variance; D019540:Area Under Curve; D003198:Computer Simulation; D016001:Confidence Intervals; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D016014:Linear Models; D015233:Models, Statistical; D015588:Observer Variation; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism; D010599:Pharmacokinetics
D004364:Pharmaceutical Preparations; D006854:Hydrocortisone