title: Orthokeratology associated microbial keratitis.
abstract: OBJECTIVE
  To report the clinical course, microbiologic findings, treatment, and outcomes of overnight orthokeratology associated microbial keratitis.
  
  
  METHODS
  Four cases of overnight orthokeratology associated microbial keratitis are reported.
  
  
  RESULTS
  Four patients aged 14-23 years (mean 18 years) who had central or paracentral corneal ulcers were included. Visual acuity at presentation ranged from 20/30 to hand motion. In all cases Pseudomonas aeruginosa was cultured from corneal scrapings or storage solution. In all patients the infection resolved with intensive topical antimicrobial treatment. Final best-corrected visual acuity ranged from 20/25 to 20/200 according to the location, size, and density of the corneal scar, which complicated all cases.
  
  
  CONCLUSIONS
  Infectious keratitis is a significant, visual threatening complication of overnight orthokeratology. Eye care practitioners should be aware of this complication and educate their patients of the importance of lens hygiene and prompt medical care when symptoms or signs of keratitis appear.
authors.affiliation: Bnai Zion Medical Center, Faculty of Medicine Technion, Haifa, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Shehadeh-Masha'our
authors.forename: F
authors.initials: F
authors.lastname: Segev
authors.forename: I S
authors.initials: IS
authors.lastname: Barequet
authors.forename: Y
authors.initials: Y
authors.lastname: Ton
authors.forename: H J
authors.initials: HJ
authors.lastname: Garzozi
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D054158:Orthokeratologic Procedures / Q000009:adverse effects*; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents