title: Wittiorumins A - F, antioxidant diels-alder-type adducts from Morus wittiorum.
abstract: Six new Diels-Alder-type adducts, wittiorumins A-F ( 1 - 6) along with the three known compounds chalcomoracin ( 7), mulberrofuran J ( 8), and mongolicin F ( 9), were isolated from the stem bark of Morus wittiorum. Their structures including their absolute configurations were determined on the basis of spectroscopic analysis and chemical methods. Some of the isolated compounds ( 1 - 4) were assayed for their antioxidant activities, among which compounds 1 - 3 were active as antioxidants, with inhibitory ratios of 73.0 %, 82.0 %, and 82.0 %, respectively, at a concentration of 10 ( - 5) M.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China.
authors.forename: Yong-Xia
authors.initials: YX
authors.lastname: Tan
authors.forename: Ren-Yi
authors.initials: RY
authors.lastname: Yan
authors.forename: Hong-Qing
authors.initials: HQ
authors.lastname: Wang
authors.forename: Ruo-Yun
authors.initials: RY
authors.lastname: Chen
authors.forename: De-Quan
authors.initials: DQ
authors.lastname: Yu
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008315:Malondialdehyde / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D018547:Plant Stems
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts; D008315:Malondialdehyde