[Primary cutaneous histoplasmosis: case report on an immunocompetent patient and review of the literature].
This report describes a case of primary cutaneous histoplasmosis in a 45-year-old male. The presentation consisted of an erythematous nodule on the back of the right hand, accompanied by nontender regional lymphadenomegaly that developed following local trauma that occurred during military training in a tunnel inhabited by bats. Histological examination of a biopsy specimen from the skin lesion showed granulomatous infiltrate, but did not show fungal elements. Culturing of this material, incubated in Sabouraud agar, showed growth of Histoplasma capsulatum. No evidence of systemic involvement or immunosuppression was found. Treatment with 400 mg/day of itraconazole orally for six months resulted in complete remission of the lesion, which was maintained one year after the end of the treatment.
Saheki
Mauricio Naoto
MN
Serviço de Infectologia, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. saheki@gmail.com
Schubach
Armando de Oliveira
Ade O
Salgueiro
Mariza de Matos
Mde M
Conceição-Silva
Fátima
F
Wanke
Bodo
B
Lazera
Márcia
M
D003881:Dermatomycoses / Q000175:diagnosis* / Q000382:microbiology; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000382:microbiology; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000175:diagnosis*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged