[Progresses in bone tissue engineering].
Bone tissure engineering plays an important role in tissure engineering. It typically uses an osteoblasts, artificial extracellular matrix (scaffold), and osteoinductive factors which promote cell attachment, differentiation, and mineralized bone formation. So it contents three problems at least: osteoblasts culture in vivo and in vitro, scaffold studies and regulation factors. Bone defect caused by trauma, tumor and inflammation is a frequent and formidable problem in clinical orthopedics. It appears that artificial bone produced by bone tissure engineering can save the problem well. With the development of tissue engineering, bone tissue engineering is developing rapidly. However, seldom experiments are on human body, and fewer productions of bone tissure engineering are used in clinic.
Li
Juan
J
Department of Orthopaedic Surgery, Zhongshan Hospital of Fudan University, Shanghai 200032, China.
Dai
Wen-da
WD
Dong
Jian
J
D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D002454:Cell Differentiation; D006801:Humans; D010006:Osteoblasts / Q000502:physiology; D010012:Osteogenesis; D023822:Tissue Engineering / Q000639:trends*; D054457:Tissue Scaffolds