title: [Potentialities of current methods for laboratory analysis in the evaluation of the severity and prevalence of nephrolithiasis in Tajikistan].
abstract: The investigation was undertaken to study a relationship between some biogeochemical and environmental factors and nephrolithiasis morbidity rates in the regions of Tajikistan. The paper presents the data of an integrated examination involving biochemical, chromatographic, and mass-spectrometric studies of 1180 patients aged 14 to 76 years who have been treated at the Dushanbe Urology Medical Center. The investigation established a relationship of an increase in ICD morbidity in poor environmental regions of the Republic of Tajikistan to the high organic and non-organic pollution, the high natural mineralization and hardness of water, and the elevated levels of chlorides, sulfates, and other salt components, which in turn influences the severity of a pathological process.
authors.forename: Z A
authors.initials: ZA
authors.lastname: Kadyrov
authors.forename: I
authors.initials: I
authors.lastname: Nusratulloev
authors.forename: S I
authors.initials: SI
authors.lastname: Suleĭmanov
authors.forename: V G
authors.initials: VG
authors.lastname: Istratov
authors.forename: V Sh
authors.initials: VSh
authors.lastname: Ramishvili
authors.forename: V I
authors.initials: VI
authors.lastname: Kondakova
authors.forename: D S
authors.initials: DS
authors.lastname: Nizomov
authors.forename: A S
authors.initials: AS
authors.lastname: Saakian
authors.forename: M
authors.initials: M
authors.lastname: Pirnazarov
authors.forename: F P
authors.initials: FP
authors.lastname: Kapsargin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000652:urine; D019963:Clinical Chemistry Tests; D006801:Humans; D013058:Mass Spectrometry; D008875:Middle Aged; D053040:Nephrolithiasis / Q000453:epidemiology* / Q000503:physiopathology* / Q000652:urine; D010447:Peptide Hydrolases / Q000652:urine; D012720:Severity of Illness Index; D013054:Spectrophotometry, Atomic; D013620:Tajikistan / Q000453:epidemiology; D055815:Young Adult
chemical_list: D015415:Biomarkers; D010447:Peptide Hydrolases