Correlation between the parameters of signal-averaged ECG and two-dimensional echocardiography in patients with arrhythmogenic right ventricular cardiomyopathy.
BACKGROUND
The correlation between parameters of two-dimensional echocardiography and signal-averaged ECG (SAECG) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) is not known well.


METHODS
Thirty-three patients (13 females, 40.3 +/- 14.4 years old) were included in this study. Both the right and left ventricular dimensions and systolic function were assessed with two-dimensional echocardiography. The SAECG was performed with high-gain amplification and filtered using bidirectional Butterworth filters between 40 and 250 Hz. We evaluated the correlation between the parameters of the SAECG and two-dimensional echocardiography.


RESULTS
The right ventricular (RV) outflow tract was the most frequently (n = 18, 54%) involved segment. Six (18%) patients had only mildly decreased RV systolic function. All the other patients had normal RV systolic function. Although localized left ventricular wall motion abnormalities were observed in 14 (42%) patients, the left ventricular ejection fraction was normal in most (n = 32, 97%). Late potentials were positive in 22 (63%) patients. There was no significant correlation between parameters of the SAECG and two-dimensional echocardiography for the entire patient population.


CONCLUSIONS
The SAECG parameters exhibited no correlation to any of two-dimensional echocardiography parameters in the patients with ARVC. Fragmented electrical activity may develop with no significant relation to the anatomical changes in the patients with ARVC.
Park
Yongwhi
Y
Department of Internal Medicine, Masan Samsung Medical Center, Masan, South Korea.
Cho
Yongkeun
Y
Lee
Dong-Yeub
DY
Jang
Gui-Lyen
GL
Lee
Hyunsang
H
Yang
Dong Heon
DH
Park
Hun-Sik
HS
Chae
Shung-Chull
SC
Jun
Jae-Eun
JE
Park
Wee-Hyun
WH
D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000401:mortality*; D002423:Cause of Death; D016009:Chi-Square Distribution; D015331:Cohort Studies; D004452:Echocardiography / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D012815:Signal Processing, Computer-Assisted; D016019:Survival Analysis; D016278:Ventricular Function, Right / Q000502:physiology