title: Rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in wound specimens and blood cultures: multicenter preclinical evaluation of the Cepheid Xpert MRSA/SA skin and soft tissue and blood culture assays.
abstract: A multicenter preclinical evaluation was conducted to evaluate the performance of two Cepheid Xpert assays for detection of methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus. Sensitivity was 97.1% and 98.3% for MRSA in wound and blood culture specimens, respectively. Sensitivity was 100% for S. aureus from both specimen types.
authors.affiliation: University of Arizona/BIO5 Institute, Tucson, Arizona 85724-5059, USA. dwolk@email.arizona.edu
authors.forename: D M
authors.initials: DM
authors.lastname: Wolk
authors.forename: M J
authors.initials: MJ
authors.lastname: Struelens
authors.forename: P
authors.initials: P
authors.lastname: Pancholi
authors.forename: T
authors.initials: T
authors.lastname: Davis
authors.forename: P
authors.initials: P
authors.lastname: Della-Latta
authors.forename: D
authors.initials: D
authors.lastname: Fuller
authors.forename: E
authors.initials: E
authors.lastname: Picton
authors.forename: R
authors.initials: R
authors.lastname: Dickenson
authors.forename: O
authors.initials: O
authors.lastname: Denis
authors.forename: D
authors.initials: D
authors.lastname: Johnson
authors.forename: K
authors.initials: K
authors.lastname: Chapin
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D001769:Blood / Q000382:microbiology*; D006801:Humans; D012680:Sensitivity and Specificity; D013203:Staphylococcal Infections / Q000175:diagnosis*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D014947:Wounds and Injuries / Q000382:microbiology*