title: Isolation of Salmonella paratyphi A from renal abscess.
abstract: Intrarenal abscesses remain a significant cause of morbidity and mortality as well as a diagnostic dilemma because a plethora of microorganisms can cause this condition. A definitive diagnosis is made by demonstrating the organisms from the aspirate and the success or failure of therapy depends upon the antimicrobial sensitivity pattern. Enteric fever is a multisystem disorder caused by invasive strains of salmonella. Salmonellosis continues to be a major public health problem, especially in developing countries. Classic enteric fever is caused by S. typhi and usually less severe enteric fevers are caused by S. paratyphi A, B, or C. However, at times S. paratyphi is capable of causing serious and often life-threatening infections like infective endocarditis, pericarditis, empyma, sino-venous thrombosis, osteomyelitis, meningitis, bone marrow infiltration, hepatitis and pancreatitis. There are anecdotal case reports in world literature of abscesses being caused by this organism. Renal involvement like bacteriuria, nephrotic syndrome and acute renal failure have been reported due to S. parayphi A. S. paratyphi A has never been implicated in renal abscess, we report one such case that was managed successfully with medical therapy.
authors.affiliation: Department of Medicine, Government Medical College and Hospital, Sector 32, Chandigarh - 160 030, UT Chandigarh, India. sanjaydcruz@gmail.com
authors.forename: Sanjay
authors.initials: S
authors.lastname: D'Cruz
authors.forename: Suman
authors.initials: S
authors.lastname: Kochhar
authors.forename: Sandeep
authors.initials: S
authors.lastname: Chauhan
authors.forename: Varsha
authors.initials: V
authors.lastname: Gupta
mesh_terms: D000038:Abscess / Q000382:microbiology*; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000382:microbiology*; D008297:Male; D010284:Paratyphoid Fever / Q000175:diagnosis* / Q000382:microbiology; D011860:Radiography, Abdominal; D012482:Salmonella paratyphi A / Q000302:isolation & purification*; D014463:Ultrasonography; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams