Thirteen X-chromosomal short tandem repeat loci multiplex data from Taiwanese.
Study results of variations in the X chromosome are useful tools in researching the genetic diversity of human populations and individual identification. We developed a 13 X chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, DXS7423) amplified in one single polymerase chain reaction. DNA samples of 113 male and 108 female Taiwanese Han subjects were successfully analyzed using this 13 X-STR multiplex system. The distributions of allele frequencies were examined for independence. DXS8377, DXS101, DXS6789, and DXS6809 were found to be the most polymorphic markers in this study. High values of discrimination power and mean exclusion chance without significant evidence of association between these markers were obtained. In conclusion, this 13 X chromosomal STR multiplex system offers considerable forensic efficiency and may be useful in forensic identification casework.
Hwa
Hsiao-Lin
HL
Department and Graduate Institute of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chang
Yih-Yuan
YY
Lee
James Chun-I
JC
Yin
Hsiang-Yi
HY
Chen
Ya-Hui
YH
Tseng
Li-Hui
LH
Su
Yi-Ning
YN
Ko
Tsang-Ming
TM
D044466:Asian People / Q000235:genetics*; D002874:Chromosome Mapping; D041321:Chromosomes, Human, X / Q000235:genetics*; D016172:DNA Fingerprinting; D005260:Female; D005787:Gene Frequency / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D013624:Taiwan
D005819:Genetic Markers