title: Clinical efficacy of neural therapy for the treatment of atopic dermatitis in dogs.
abstract: The aim of this trial was to assess the clinical efficacy of neural therapy (NT) when treating canine atopic dermatitis. Eighteen dogs (no control group), with at least a 12-month history of having nonseasonal atopic dermatitis, were included. No medication with either glucocorticoids or cyclosporin was allowed during the trial. One set of NT was given by injecting an intravenous dose of 0.1 mg/kg of a 0.7% procaine solution, followed by 10 to 25 intradermal injections of the same solution in a volume of 0.1-0.3 mL per site. Dogs were given 6-13 sets of NT during the therapy. The dermatological condition of each patient was evaluated before and after the treatment using two scales: the pruritus visual analogue scale (PVAS) and the canine atopic dermatitis extent and severity index (CADESI). The reduction of pruritus was statistically significant using a Wilcoxon matched-pairs signed-ranks test (P < 0.001). No adverse side effects were observed. NT seems to be an effective alternative to control signs related to canine atopic dermatitis.
authors.affiliation: Department of Physiology and Pharmacology, School of Veterinary Medicine, National Autonomous University of Mexico (UNAM), Av. Universidad 3000, Mexico City 04510, Mexico.
authors.forename: Adriana
authors.initials: A
authors.lastname: Bravo-Monsalvo
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Vázquez-Chagoyán
authors.forename: Lilia
authors.initials: L
authors.lastname: Gutiérrez
authors.forename: Héctor
authors.initials: H
authors.lastname: Sumano
mesh_terms: D000772:Anesthesia, Local / Q000662:veterinary*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy* / Q000473:pathology; D004285:Dogs; D004334:Drug Administration Schedule; D005260:Female; D008297:Male; D011343:Procaine / Q000008:administration & dosage* / Q000627:therapeutic use*
chemical_list: D000779:Anesthetics, Local; D011343:Procaine