Sinus grafting using autogenous bone and platelet-rich plasma: histologic outcomes in humans.
Four partially edentulous patients received particulate autogenous bone and platelet-rich plasma (PRP) in one sinus and particulate autogenous bone alone in the contralateral sinus. After 6 months of healing, two or three Osseotite implants were inserted, and an additional Osseotite mini-implant was placed into the graft through the lateral wall of the sinus. At abutment connection, the mini-implants were retrieved for histologic examination. Despite similar clinical and radiographic healing patterns, a higher bone-to-implant contact rate was observed on the implants placed in bone and PRP than on those placed in bone only (46.75% +/- 13.6% versus 20.5% +/- 5.57%, respectively).
Aimetti
Mario
M
Department of Biomedical Sciences and Human Oncology, Section of Periodontology, University of Torino, Torino, Italy. mario.aimetti@unito.it
Romano
Federica
F
Dellavia
Claudia
C
De Paoli
Sergio
S
D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery; D000539:Alveolar Process / Q000473:pathology; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001861:Bone Regeneration / Q000502:physiology; D016025:Bone Transplantation / Q000379:methods*; D000044:Dental Abutments; D015921:Dental Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation / Q000601:surgery; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery*; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D053657:Platelet-Rich Plasma; D013499:Surface Properties; D016896:Treatment Outcome
D015921:Dental Implants