title: Audiogenic epilepsy in young mice of different strains after neonatal semax treatment.
abstract: Neonatal (from day 2 to day 7 of life) injection of neuropeptide semax to mice of 5 inbred strains significantly reduced predisposition to audiogenic epilepsy in only one-month-old DBA/2J mice, which manifested in changes in the mean audiogenic sensitivity score and percentage of animals dead as a result of acoustic stimulation.
authors.affiliation: Laboratory of Behavioral Physiology and Genetics, Biological Faculty, M. V. Lomonosov Moscow University, Russia.
authors.forename: O S
authors.initials: OS
authors.lastname: Boyarshinova
authors.forename: O V
authors.initials: OV
authors.lastname: Perepelkina
authors.forename: N V
authors.initials: NV
authors.lastname: Markina
authors.forename: I I
authors.initials: II
authors.lastname: Poletaeva
mesh_terms: D000161:Acoustic Stimulation; D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D000831:Animals, Newborn; D004198:Disease Susceptibility; D020195:Epilepsy, Reflex / Q000188:drug therapy* / Q000235:genetics / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010446:Peptide Fragments / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D018696:Neuroprotective Agents; D010446:Peptide Fragments; C048487:ACTH (4-7), Pro-Gly-Pro-; D000324:Adrenocorticotropic Hormone