Improvement of coagulation laboratory practice in Thailand: the first-year experience of the national external quality assessment scheme for blood coagulation.
BACKGROUND
In Thailand until 2005 there had been no external quality assessment scheme at the national level for blood coagulation tests. Only a few laboratories had an external quality assessment for these tests. In the year 2005, the Thailand National External Quality Assessment Scheme for Blood Coagulation was founded.


OBJECTIVE
To describe the establishment of the Thailand National External Quality Assessment Scheme for Blood Coagulation (including problems encountered and solutions), its progression and expansion, and the improvement of coagulation laboratory practice in Thailand during 2 trial surveys and 4 formal surveys conducted in the first 1 1/2 years.


METHODS
Between 2005 and 2006, the external quality assessment samples for prothrombin time/international normalized ratio and activated partial thromboplastin time were distributed to the participants as well as the instructions and suggestions for the improvement of laboratory practice. From the data collected, the all-method coefficient of variation of the international normalized ratio and activated partial thromboplastin time was calculated for each survey.


RESULTS
The number of participants increased during the first 1 1/2 years that the surveys were conducted, from 109 to 127. Survey data demonstrate an improvement in response rate and an increase in the number of laboratories that determine their own reference ranges and repeat this for every change of reagent lot, using the appropriate anticoagulant. The increased precision of tests is indicated by the decrease of the all-method coefficient of variation of the international normalized ratio and activated partial thromboplastin time. Examples of individual laboratory improvement through feedback are also described.


CONCLUSIONS
The improvement of coagulation laboratory practice both through the instructions provided and liaison with participants was observed during the course of this scheme.
Tientadakul
Panutsaya
P
Department of Clinical Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand. siptd@mahidol.ac.th
Opartkiattikul
Nisarat
N
Wongtiraporn
Wanida
W
D001777:Blood Coagulation; D001780:Blood Coagulation Tests / Q000592:standards*; D006801:Humans; D007755:Laboratories, Hospital / Q000592:standards*; D011785:Quality Assurance, Health Care; D011786:Quality Control; D012016:Reference Values; D013048:Specimen Handling / Q000592:standards; D011795:Surveys and Questionnaires; D013785:Thailand