title: Experiences with surgical treatment of ventricle septal defect as a post infarction complication.
abstract: BACKGROUND
  Complications of acute myocardial infarction (AMI) with mechanical defects are associated with poor prognosis. Surgical intervention is indicated for a majority of these patients. The goal of surgical intervention is to improve the systolic cardiac function and to achieve a hemodynamic stability. In this present study we reviewed the outcome of patients with post infarction ventricular septal defect (PVSD) who underwent cardiac surgery.
  
  
  METHODS
  We analysed retrospectively the hospital records of 41 patients, whose ages range from 48 to 81, and underwent a surgical treatment between 1990 and 2005 because of PVSD.
  
  
  RESULTS
  In 22 patients concomitant coronary artery bypass grafting (CAGB) was performed. In 15 patients a residual shunt was found, this required re-op in seven of them. The time interval from infarct to rupture was 8.7 days and from rupture to surgery was 23.1 days. Hospital mortality in PVSD group was 32%. The mortality of urgent repair within 3 days of intractable cardiogenic shock was 100%. The mortality of patients with an anterior VSD and a posterior VSD was 29.6% vs 42.8%, respectively. All patients who underwent the surgical repair later than day 36 survived.
  
  
  CONCLUSIONS
  Surgical intervention is indicated for a majority of patients with mechanical complications. Cardiogenic shock remains the most important factor that affects the early results. The surgical repair of PVSD should be performed 4-5 weeks after AMI. To improve surgical outcome and hemodynamics the choice of surgical technique and surgical timing as well as preoperative management should be tailored for each patient individually.
authors.affiliation: Department of Thoracic Cardiovascular Surgery, University of Göttingen, Göttingen, Germany. dr_coskunok@yahoo.de
authors.forename: Kasim Oguz
authors.initials: KO
authors.lastname: Coskun
authors.forename: Sinan Tolga
authors.initials: ST
authors.lastname: Coskun
authors.forename: Aron Frederik
authors.initials: AF
authors.lastname: Popov
authors.forename: Jose
authors.initials: J
authors.lastname: Hinz
authors.forename: Jan Dieter
authors.initials: JD
authors.lastname: Schmitto
authors.forename: Kerstin
authors.initials: K
authors.lastname: Bockhorst
authors.forename: Kathrin Monika
authors.initials: KM
authors.lastname: Stich
authors.forename: Reiner
authors.initials: R
authors.lastname: Koerfer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000379:methods*; D005260:Female; D005858:Germany / Q000453:epidemiology; D017052:Hospital Mortality; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D011379:Prognosis; D012189:Retrospective Studies; D012770:Shock, Cardiogenic / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D018658:Ventricular Septal Rupture / Q000209:etiology / Q000401:mortality / Q000601:surgery*