title: Mitral valve replacement in a patient with idiopathic hypereosinophilic syndrome and pulmonary arterial hypertension.
abstract: OBJECTIVE
  Idiopathic hypereosinophilic syndrome, a rarely seen systemic disease, may cause cardiac valvular lesions by eosinophilic infiltration. This report describes management of a 25-year-old woman with idiopathic hypereosinophilic syndrome, severe mitral stenosis, and pulmonary arterial hypertension.
  
  
  METHODS
  The patient was presented with haemoptysia and dyspnea on exertion. Echocardiography showed severe mitral stenosis and pulmonary arterial hypertension.
  
  
  RESULTS
  After hematological stabilization, she underwent mitral valve replacement using a No. 27 bovine pericardial valve. In the intensive care unit she had a pulmonary hypertensive crisis, which ameliorated gradually with sedation and nitroglycerin. She was extubated and discharged on the second and seventh days, respectively.
  
  
  CONCLUSIONS
  Surgical experience for the patients with mitral dysfunction caused by idiopathic hypereosinophilic syndrome is limited. When mitral valve replacement is needed, the ideal type of prosthesis remains unclear and the presence of pulmonary arterial hypertension further complicates the management. We think that bioprosthetic valves would be the appropriate choice in eosinophilic mitral dysfunction requiring valve replacement.
authors.affiliation: Department of Cardiovascular Surgery, Suleyman Demirel University Medical School, Isparta, Turkey. kirisilker@yahoo.com
authors.forename: Ilker
authors.initials: I
authors.lastname: Kiris
authors.forename: Huseyin
authors.initials: H
authors.lastname: Okutan
authors.forename: Tulay
authors.initials: T
authors.lastname: Peker
authors.forename: Suleyman M
authors.initials: SM
authors.lastname: Aslan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sahin
authors.forename: Sema
authors.initials: S
authors.lastname: Bircan
mesh_terms: D000328:Adult; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000601:surgery; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*