Sensitization of the thymus to hypoplastic effect of glucocorticoids after long-term hypokinetic stress.
Long-term hypokinesia increases sensitivity of the thymus to the hypoplastic effect of glucocorticoid preparation triamcinolone acetonide by potentiating the proapoptotic effect of the glucocorticoid.
Tseilikman
V E
VE
Chelyabinsk State Medical Academy, Russian Ministry of Health, Russia.
Filimonova
T A
TA
Boyarinova
N V
NV
Sibiryak
S V
SV
Kozochkin
D A
DA
Sinitsky
A I
AI
D000818:Animals; D002453:Cell Cycle / Q000187:drug effects; D005260:Female; D005938:Glucocorticoids / Q000494:pharmacology*; D007103:Immobilization / Q000502:physiology / Q000523:psychology; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical / Q000502:physiology / Q000523:psychology; D013315:Stress, Psychological; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D014221:Triamcinolone / Q000737:chemistry / Q000494:pharmacology
D005938:Glucocorticoids; D014221:Triamcinolone