Identification of a new HLA-DRB1*14 variant, HLA-DRB1*1478, in a Korean individual.
We report the identification of novel allele HLA-DRB1*1478 that was found during routine high-resolution sequence-based typing of the cord blood unit in Korean population. The DRB1*1478 allele shows two nucleotide differences from DRB1*1463 in exon 2 at nucleotide position 344 (G-->T) and 345 (T-->G), resulting in an amino acid change, Gly86Val.
Han
S H
SH
Research Institute of Biotechnology, Histostem Co., Seoul, Korea. immunogenetics@seoulcord.co.kr
Jung
S M
SM
Park
S R
SR
Chung
S Y
SY
Han
H
H
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data; D016415:Sequence Alignment
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C538926:HLA-DRB1*14:78 antigen