Hyperviscosity syndrome in ovariectomized rats.
Ovariectomy reduces blood levels of sex hormones and considerably increases blood viscosity due to an increase in hematocrit and plasma fibrinogen content, disorders in viscoelastic characteristics of erythrocytes, and increase of their aggregation activity. Changes in the macrorheology are mainly responsible for the development of the hyperviscosity syndrome.
Plotnikova
A M
AM
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Siberian State Medical University, Tomsk, Russia.
Shulgau
Z T
ZT
Plotnikova
T M
TM
Aliev
O I
OI
Borovskaya
T G
TG
D000818:Animals; D001783:Blood Flow Velocity; D001809:Blood Viscosity; D004903:Erythrocyte Aggregation; D004967:Estrogens / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006400:Hematocrit; D006439:Hemodynamics; D006801:Humans; D010052:Ovariectomy; D011374:Progesterone / Q000097:blood; D051381:Rats; D012212:Rheology; D013577:Syndrome
D004967:Estrogens; D011374:Progesterone; D005340:Fibrinogen