title: 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters.
abstract: Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.
authors.affiliation: Department of Chemistry, University College London, 20 Gordon Street, London, UK.
authors.forename: Jaskiranjit
authors.initials: J
authors.lastname: Kang
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Richardson
authors.forename: Derek
authors.initials: D
authors.lastname: Macmillan
mesh_terms: D015097:3-Mercaptopropionic Acid / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D011506:Proteins / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D010455:Peptides; D011506:Proteins; D015097:3-Mercaptopropionic Acid