Essure hysteroscopic tubal occlusion device for the treatment of hydrosalpinx prior to in vitro fertilization-embryo transfer in patients with a contraindication for laparoscopy.
OBJECTIVE
To investigate the success rate of proximal tubal occlusion with Essure devices in subfertile women with hydrosalpinges, and to observe the results of subsequent treatment with IVF.


METHODS
Prospective, single-arm, clinical study.


METHODS
University hospital and teaching hospital.


METHODS
Ten women with uni- or bilateral hydrosalpinges prior to IVF. In all patients laparoscopy was felt to be contraindicated.


METHODS
Hysteroscopic placement of Essure devices in an office setting.


METHODS
Placement rate, successful proximal tubal occlusion, and pregnancy rate after IVF.


RESULTS
All patients had successful placement of the Essure devices without any complications. Proximal tubal occlusion was confirmed by hysterosalpingography in 9 out of 10 patients. A 40% ongoing pregnancy rate was achieved with 20% life births after one IVF cycle and/or frozen embryo transfer.


CONCLUSIONS
Proximal occlusion of hydrosalpinges with Essure devices before IVF is a successful treatment for patients with a contraindication for salpingectomy.
Mijatovic
Velja
V
Department of Reproductive Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. mijatovic@vumc.nl
Veersema
Sebastiaan
S
Emanuel
Mark Hans
MH
Schats
Roel
R
Hompes
Peter G A
PG
D000328:Adult; D004624:Embryo Transfer / Q000295:instrumentation / Q000379:methods*; D005187:Fallopian Tubes / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D015907:Hysteroscopy / Q000379:methods*; D007231:Infant, Newborn; D007247:Infertility, Female / Q000628:therapy; D010535:Laparoscopy / Q000009:adverse effects; D011247:Pregnancy; D011446:Prospective Studies