title: Acute anuric renal failure with streptokinase therapy in a patient with acute venous thromboembolic disease and the review of renal side effects of streptokinase.
abstract: The benefits of thrombolytic therapy in acute myocardial infarction are now well established. However many uncertainties, such as adverse effects, are still remain in venous thromboembolic disease. We describe a unique patient who treated with streptokinase for the methylen tetrahydrofolate reductase mutation associated acute deep vein thrombosis and massive pulmonary embolism. After therapy patient developed acute anuric renal failure without an evidence of bleeding or immunologic reaction and we would like to review the renal side effects of streptokinase in patients with venous thromboembolic disease.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey. zponen@yahoo.com
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Onen
authors.forename: Oznur
authors.initials: O
authors.lastname: Akkoca Yildiz
authors.forename: Banu
authors.initials: B
authors.lastname: Eriş Gülbay
authors.forename: Gülseren
authors.initials: G
authors.lastname: Karabiyikoğlu
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000235:genetics; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000188:drug therapy / Q000235:genetics
chemical_list: D005343:Fibrinolytic Agents; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D013300:Streptokinase