[Pulmonary embolism in a patient with large cell lung carcinoma during chemotherapy-case report].
The patient, a 64-year-old woman, was diagnosed as having large cell carcinoma(stageIV)eighteen months ago. She received long-term chemotherapy, and her disease stabilized. She was admitted to our hospital with dyspnea and diagnosed with a pulmonary embolism by chest computed tomography(CT)and angiography of pulmonary artery. As a result of thrombolytic therapy and anticoagulant therapy, the thrombus decreased in size and her condition improved. Insertion of a vena cava filter and continuation of anticoagulant therapy were performed to prevent recurrence of PE. In this case, there were many prothrombogenic factors such as advanced malignancy, a long period of chemotherapy, corticosteroids, granulocyte-colony stimulating factor(G-CSF)and decreased physical activity. Thrombosis is a frequent complication in cancer patients and represents an important cause of morbidity and mortality. Great care should be taken for complications of thrombosis in cancer treatment.
Oshita
Hideto
H
Dept. of Respiratory Medicine, Chugoku Rosai General Hospital, Japan.
Itai
Junji
J
Omori
Keitaro
K
Okamoto
Naoki
N
Awaya
Yukikazu
Y
D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018287:Carcinoma, Large Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
D000925:Anticoagulants; D000970:Antineoplastic Agents