title: [Serological markers for hepatitis B virus in young women attended by the Family Health Program in Vitória, Espírito Santo, 2006].
abstract: The aim of this study was to determine the frequencies of serological markers for hepatitis B and risk factors associated with HBV infection among young women living in Vitória, Espírito Santo, where vaccination for newborns and adolescents started in 1994 and 2000, respectively. This was a population-based study performed by sampling in three health regions of Vitória in 2006. Interviews were held and HBsAg, anti-HBc and anti-HBs were investigated. Out of 1,200 women selected, 1,029 (85.7%) were enrolled. The median age was 23 years (interquartile range: 20-26 years) and 93.2% had had more than four years of schooling. Forty-three women (4.2%; 95%CI 2.97%-5.43%) were positive for anti-HBc total, and nine, for HBsAg (0.9%; 95%CI 0.4%-1.6%)]. There were 466 positive anti-HBs tests (45.3%; 95%CI 42.2%-48.4%), of which 427 were negative for anti-HBc and HBsAg. Monthly income of up to four minimum monthly salaries was the only variable independently associated with positive anti-HBc tests (OR = 2.6: 95%CI 1.06-6.29). These data show low prevalence of the hepatitis B virus and its better-known risk factors. The prevalence of positive anti-HBs tests with negative anti-HBc and HBsAg tests reflects the vaccine coverage in the municipality in this group (43.7%). It was not possible to determine any significant risk factors for hepatitis B virus acquisition among this population.
authors.affiliation: Programa de Pós-Graduação em Doenças Infecciosas, Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, ES, Brazil. ninive-figueiredo@ig.com.br
authors.forename: Nínive Camillo de
authors.initials: NC
authors.lastname: Figueiredo
authors.forename: Kimberly
authors.initials: K
authors.lastname: Page-Shafer
authors.forename: Fausto Edmundo Lima
authors.initials: FE
authors.lastname: Pereira
authors.forename: Angélica Espinosa
authors.initials: AE
authors.lastname: Miranda
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines