title: [Analysis of tear enzymes in the diagnosis of obstructive jaundice associated with subhepatic cholestasis].
abstract: The activity of enzymes, such as alkaline phosphatase, gamma-glutamyl transpeptidase, and leicine aminopeptidase, was found to be increased in the serum and tear of 28 patients with obstructive jaundice. In malignant tumor-induced jaundice, the activity of the enzymes, the indicators of cholestasis, was higher than that in obstructive jaundice caused by extrahepatic bile duct calculi. A new method has been devised for noninvasive diagnosis of obstructive jaundice from tear enzyme immunoassay. The method is simple, reliable, and usable at a clinical laboratory.
authors.forename: N A
authors.initials: NA
authors.lastname: Terekhina
authors.forename: M F
authors.initials: MF
authors.lastname: Zarivchatskiĭ
authors.forename: N V
authors.initials: NV
authors.lastname: Soldatenko
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001651:Cholestasis, Extrahepatic / Q000150:complications / Q000201:enzymology*; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D013666:Tears / Q000201:enzymology*