title: Pathology and diagnostic options of lower limb compartment syndrome.
abstract: BACKGROUND
  The indication of surgical treatment in lower limb compartment syndrome mostly depends on the clinical signs which can be often uncertain, resulting in delayed insufficient intervention.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the progression of compartment syndrome by measuring of intracompartmental pressure and monitoring of decreased tissular oxygenation, indicating an insufficient secondary microcirculation.
  
  
  METHODS
  16 patients were examined in our study (12 males, 4 females, mean age: 62.7+/-9.5 years), who underwent acute lower limb revascularization surgery for a critical (lasting more than 4 hours) limb ischemia. The indications were: 5 iliac artery embolizations and 11 femoral artery occlusions. After revascularization, on the second postoperative day, we detected significant lower limb edema and swelling of several grade. To monitor the elevated intracompartmental pressure (ICP) and to evaluate the extremital circulation, we used KODIAG pressure meter and the tissular oxygen saturation (StO2) was measured by near-infrared-spectroscopy.
  
  
  RESULTS
  In 12 cases the ICP exceeded the critical 40 mmHg. In these patients the average StO2 was 50-53%, in spite of complete recanalization. In these cases we made urgent, semi-open fasciotomy. In 4 cases, where the clinical aspect showed compartment syndrome, the measured parameters did not indicate a surgical intervention (ICP: 25-35 mmHg, StO2: around normal).
  
  
  CONCLUSIONS
  A novel approach in our examination is that, besides empirical therapeutic guidelines generally applied in clinical practice, we established an objective, parameter-based ("evidence based medicine") surgical indication strategy for the lower limb compartment syndrome. Our parameter results produced by the above pressure and saturation measurements help the clinicians to decide between conservative and operative treatment of the disease.
authors.affiliation: Department of General and Vascular Surgery, Faculty of Medicine, University of Pécs, Pécs, Hungary. aratoendre@gmail.com
authors.forename: E
authors.initials: E
authors.lastname: Arató
authors.forename: M
authors.initials: M
authors.lastname: Kürthy
authors.forename: L
authors.initials: L
authors.lastname: Sínay
authors.forename: G
authors.initials: G
authors.lastname: Kasza
authors.forename: G
authors.initials: G
authors.lastname: Menyhei
authors.forename: S
authors.initials: S
authors.lastname: Masoud
authors.forename: A
authors.initials: A
authors.lastname: Bertalan
authors.forename: Zs
authors.initials: Z
authors.lastname: Verzár
authors.forename: L
authors.initials: L
authors.lastname: Kollár
authors.forename: E
authors.initials: E
authors.lastname: Roth
authors.forename: G
authors.initials: G
authors.lastname: Jancsó
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003161:Compartment Syndromes / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D000071938:Fasciotomy; D005260:Female; D006801:Humans; D007511:Ischemia / Q000503:physiopathology; D035002:Lower Extremity / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress