title: Feline digital phaeohyphomycosis due to Exophiala jeanselmei.
abstract: The black nodule measuring 1 cm in diameter developed in the base of nail of an 8-year-old Japanese domestic male cat. Histological examination of the excised nodule revealed a granulomatous lesion extending from the epidermis to adjacent bone. The lesion was consisted of diffuse infiltration of macrophages with epithelioid cells and multinucleated giant cells. These macrophages contained a few to numerous yeast-like brown pigmented fungus cells with a spherical shape and dark thick wall. The PCR amplification with universal primers of the 28S ribosomal RNA gene yielded a 628-bp fragment and the direct sequence confirmed that the diagnosis of the lesion was phaeohyphomycosis caused by the pathogenic dematiaceous fungus, Exophiala jeanselmei.
authors.affiliation: College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Maeda
authors.forename: Hisashi
authors.initials: H
authors.lastname: Shibuya
authors.forename: Yoko
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: Takuma
authors.initials: T
authors.lastname: Miyoshi
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Irie
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Sato
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000382:microbiology* / Q000601:surgery; D002415:Cats; D005093:Exophiala / Q000145:classification*; D005534:Foot Diseases / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D009181:Mycoses / Q000382:microbiology / Q000601:surgery / Q000662:veterinary*