Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles.
Doped up: The incorporation of Zn(2+) dopants in tetrahedral sites leads to the successful magnetism tuning of spinel metal ferrite nanoparticles (see picture). (Zn(0.4)Mn(0.6))Fe(2)O(4) nanoparticles exhibit the highest magnetization value among the metal ferrite nanoparticles. Such high magnetism results in the largest MRI contrast effects (r2=860 mm(-1) s(-1)) reported to date and also huge hyperthermic effects.
Jang
Jung-tak
JT
Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
Nah
Hyunsoo
H
Lee
Jae-Hyun
JH
Moon
Seung Ho
SH
Kim
Min Gyu
MG
Cheon
Jinwoo
J
D016923:Cell Death; D003287:Contrast Media / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D005334:Fever / Q000139:chemically induced*; D006367:HeLa Cells; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use / Q000648:ultrastructure; D015032:Zinc / Q000737:chemistry
D003287:Contrast Media; D005290:Ferric Compounds; C001215:ferrite; D015032:Zinc