A blaVEB-1 variant, blaVEB-6, associated with repeated elements in a complex genetic structure.
bla(VEB-6) was found on the Proteus mirabilis chromosome in a context similar to those of bla(VEB-1a) and bla(VEB-1b), in a truncated gene cassette flanked by 135-bp elements and duplications of the 3'-conserved segment of class 1 integrons. A linked aacA4-aadB-dfrA1-orfC cassette array includes components of Tn1331, illustrating the complex mosaicism of multiresistance regions.
Zong
Zhiyong
Z
Centre for Infectious Diseases and Microbiology, Westmead Hospital, the University of Sydney, Westmead, NSW, Australia.
Partridge
Sally R
SR
Iredell
Jonathan R
JR
D001483:Base Sequence; D004251:DNA Transposable Elements; D029968:Escherichia coli Proteins; D008969:Molecular Sequence Data; D011513:Proteus mirabilis / Q000201:enzymology; D011532:Providencia / Q000201:enzymology*; D011550:Pseudomonas aeruginosa / Q000201:enzymology*; D012091:Repetitive Sequences, Nucleic Acid; D001618:beta-Lactamases / Q000235:genetics*
D004251:DNA Transposable Elements; D029968:Escherichia coli Proteins; C119424:beta-lactamase VEB-1, E coli; D001618:beta-Lactamases