Albidopyrone, a new alpha-pyrone-containing metabolite from marine-derived Streptomyces sp. NTK 227.
Albidopyrone, a new alpha-pyrone-containing secondary metabolite, was produced by Streptomyces sp. NTK 227, a strain isolated from Atlantic Ocean sediment and found to be a member of the Streptomyces albidoflavus 16S rRNA gene clade. The structure of the compound was determined by MS and NMR spectroscopy, and found to have a moderate inhibitory activity against protein-tyrosin phosphatase B.
Hohmann
Claudia
C
Mikrobiologisches Institut, Universität Tübingen, Tübingen, Germany.
Schneider
Kathrin
K
Bruntner
Christina
C
Brown
Roselyn
R
Jones
Amanda L
AL
Goodfellow
Michael
M
Krämer
Marco
M
Imhoff
Johannes F
JF
Nicholson
Graeme
G
Fiedler
Hans-Peter
HP
Süssmuth
Roderich D
RD
D000081:Acetamides / Q000737:chemistry* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D005285:Fermentation; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011753:Pyrones / Q000737:chemistry* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces / Q000737:chemistry* / Q000145:classification / Q000378:metabolism; D014871:Water Microbiology
D000081:Acetamides; D000900:Anti-Bacterial Agents; D011753:Pyrones; C544382:albidopyrone