title: Intrathecal methotrexate-induced acute chorea.
abstract: Intrathecal methotrexate is the mainstay of central nervous system prophylaxis in acute lymphoblastic leukemia. We describe a patient who developed acute chorea after last dose of intrathecal methotrexate therapy and recovered completely.
authors.affiliation: Departments of Neurology, Sişli Etfal Education and Research Hospital, Istanbul, Turkey. orkenada@superonline.com
authors.forename: Dilek
authors.initials: D
authors.lastname: Necioğlu Orken
authors.forename: Yldz
authors.initials: Y
authors.lastname: Yldrmak
authors.forename: Gülay
authors.initials: G
authors.lastname: Kenangil
authors.forename: Nursu
authors.initials: N
authors.lastname: Kandraloğlu
authors.forename: Hulki
authors.initials: H
authors.lastname: Forta
authors.forename: Münevver
authors.initials: M
authors.lastname: Celik
mesh_terms: D000208:Acute Disease; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002819:Chorea / Q000139:chemically induced* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate