High-purity discrete PEG-oligomer crystals allow structural insight.
To great (monodisperse) lengths: An improved synthesis of purer ethylene glycol (EG) oligomers allows access to 16- and 32-mers pure enough for multiple incorporation, and also to the longest (48-mer) discrete EG oligomer yet reported. The high purity enables the first crystallizations and hence the first glimpses of secondary 3(10)-helical PEG structures.
French
Alister C
AC
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford, UK.
Thompson
Amber L
AL
Davis
Benjamin G
BG
D003460:Crystallization; D019855:Ethylene Glycol / Q000138:chemical synthesis / Q000737:chemistry; D013058:Mass Spectrometry; D015394:Molecular Structure; D011092:Polyethylene Glycols / Q000138:chemical synthesis* / Q000737:chemistry*; D014961:X-Ray Diffraction
D011092:Polyethylene Glycols; D019855:Ethylene Glycol