On the role of cell signaling models in cancer research.
The main objective of this review is to emphasize the role and importance of the careful mathematical/computational modeling of signaling networks for the understanding of aberrant signaling in cancer and for the development of targeted therapies.
Ventura
Alejandra C
AC
University of Michigan, Ann Arbor, Michigan 48109, USA.
Jackson
Trachette L
TL
Merajver
Sofia D
SD
D008954:Models, Biological; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D015398:Signal Transduction