[Tuberculous pleurisy after tumour necrosis factor-alpha antagonist usage: case report].
A thirty-six year old male patient presented with dyspnea, right-sided chest pain, night sweats and intermittent fever. He has a history of ankylosing spondylitis treated with tumour necrosis factor-alpha (TNF-alpha) antagonist (infliximab). Computed tomography of the chest showed mediastinal lymphadenopathy, right-sided pleural effusion, and atelectasis. The pleural fluid was exudative with lymphocyte dominance. Closed pleural biopsy was nondiagnostic. The adenosine deaminase level of the pleural fluid was 110 U/L. In light of these findings, the patient was diagnosed as tuberculous pleurisy and antituberculous treatment was given. After one month, pleural fluid was markedly reduced.
Akoğlu
Sebahat
S
Department of Chest Diseases, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey. sebahatakoglu@hotmail.com
Babayiğit
Cenk
C
Karazincir
Sinem
S
Balci
Ali
A
Hanta
Ismail
I
D000328:Adult; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use*; D006801:Humans; D000069285:Infliximab; D008297:Male; D010996:Pleural Effusion / Q000166:cytology / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014396:Tuberculosis, Pleural / Q000139:chemically induced*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D000911:Antibodies, Monoclonal; D000995:Antitubercular Agents; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab