title: Congenital herpes simplex virus infection: two unique cutaneous presentations associated with probable intrauterine transmission.
abstract: Cutaneous manifestations of congenital herpes simplex virus (HSV) have been classically described as grouped vesicles on an erythematous base. We report two cases of HSV infection wherein both infants presented at birth with widespread erosions and an absence of vesicles or vesicopustules. The presence of skin lesions at birth, neurologic changes seen on radiographic imaging, and a cesarean section delivery in one case suggests intrauterine transmission in both neonates.
authors.affiliation: Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA.
authors.forename: Laine H
authors.initials: LH
authors.lastname: Koch
authors.forename: Randall G
authors.initials: RG
authors.lastname: Fisher
authors.forename: Catherine
authors.initials: C
authors.lastname: Chen
authors.forename: Maura M
authors.initials: MM
authors.lastname: Foster
authors.forename: W Thomas
authors.initials: WT
authors.lastname: Bass
authors.forename: Judith V
authors.initials: JV
authors.lastname: Williams
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006561:Herpes Simplex / Q000151:congenital / Q000473:pathology* / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009336:Necrosis; D012867:Skin / Q000473:pathology*