title: Electron emission from photo-excited testosterone in water-ethanol solution.
abstract: Testosterone (TES; 4-androstene-17beta-ol-3-on) is found for the first time to eject electrons from its singlet excited state in water-ethanol solvent mixture. This ability was very recently also observed for 17beta-estradiol (17betaE2) and progesterone (PRG)/1/. With increasing TES-concentration, the yield of solvated electrons (e(s)(-)) is decreasing, because of "associate" formation. At higher absorbed UV-doses (lambda=254 nm) the e(s)(-) yield is passing a sharp maximum by formation of TES-ethanol adducts, which are able likewise to emit electrons when excited. At prolonged irradiation the resulting photolytic products of TES-ethanol adducts are also able to emit electrons. The capability of the hormones: 17betaE2, PRG and TES to eject electrons and the resulting metabolites, some of which can induce cancer, is discussed.
authors.affiliation: The University of Vienna, Department of Nutritional Sciences, Section Radiation Biology, A-1090 Vienna, Althanstr. 14, UZAII, Austria. nikola.getoff@univie.ac.at
authors.forename: Nikola
authors.initials: N
authors.lastname: Getoff
authors.forename: Heike
authors.initials: H
authors.lastname: Schittl
authors.forename: Johannes
authors.initials: J
authors.lastname: Hartmann
authors.forename: Ruth Maria
authors.initials: RM
authors.lastname: Quint
mesh_terms: D004583:Electrons; D000431:Ethanol; D010782:Photolysis; D012996:Solutions; D013739:Testosterone / Q000737:chemistry* / Q000528:radiation effects; D014466:Ultraviolet Rays; D014867:Water
chemical_list: D012996:Solutions; D014867:Water; D000431:Ethanol; D013739:Testosterone