Gonadotoxic effect of polychlorobiphenyls.
The distribution of polychlorobiphenyls (environmental pollutants) in the reproductive organs and fatty tissues of rats was analyzed and selective accumulation of the toxicants in the epididymis, but not in the ovaries, was demonstrated. Reduction of the fertilizing activity of the ejaculate after chronic exposure to polychlorobiphenyls was detected. Mechanisms of spermatogenic dysfunction under conditions of high technogenic load are discussed.
Gromenko
D S
DS
Bashkir State Medical University, Ufa, Bashkiria, Russia.
Galimov
Sh N
ShN
Amirova
Z K
ZK
Abdullina
A Z
AZ
Gromenko
Yu Yu
YY
Galimova
E F
EF
D000818:Animals; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D005298:Fertility / Q000187:drug effects; D005835:Genitalia / Q000187:drug effects*; D008297:Male; D011078:Polychlorinated Biphenyls / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats
D004785:Environmental Pollutants; D011078:Polychlorinated Biphenyls