title: [The influence of antihypertensive agents on plasmatic and vascular-thrombocytic homeostasis in metabolic syndrome].
abstract: The combined therapy with enalapril and prolonged-release verapamil, as well as with enalapril and moxonidine significantly increases the level of antiatherogenic high-density-lipoprotein cholesterol, reduces the atherogenicity coefficients, decreases the concentrations of glucose, glycosylated hemoglobin, and soluble fibrinmonomeric complexes and the aggregation activity of thrombocytes, activates plasminogen in the blood of patients under conditions of metabolic syndrome with arterial hypertension. At the same time the enalapril monotherapy has no significant influence on the parameters of lipid and carbohydrate metabolism and the plasmatic and vascular-thrombocytic homeostasis.
authors.forename: A I
authors.initials: AI
authors.lastname: Vengerovskiĭ
authors.forename: E M
authors.initials: EM
authors.lastname: Idrisova
authors.forename: E A
authors.initials: EA
authors.lastname: Bushkova
authors.forename: E I
authors.initials: EI
authors.lastname: Mananko
authors.forename: N M
authors.initials: NM
authors.lastname: Krasnova
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001792:Blood Platelets / Q000166:cytology / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000188:drug therapy; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D008055:Lipids