title: Both hypoxia and work are required to enhance expression of myoglobin in skeletal muscle. Focus on "Hypoxia reprograms calcium signaling and regulates myoglobin expression".
authors.affiliation: Dept. of Physiology & Biophysics, Albert Einstein College of Medicine, Yeshiva Univ., 1300 Morris Park Ave., Bronx, NY 10461, USA. bwitten@aecom.yu.edu
authors.forename: Beatrice A
authors.initials: BA
authors.lastname: Wittenberg
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D019703:Calcineurin / Q000378:metabolism; D020746:Calcium Channels, L-Type / Q000378:metabolism*; D020013:Calcium Signaling; D006801:Humans; D000860:Hypoxia / Q000235:genetics / Q000378:metabolism* / Q000503:physiopathology; D051379:Mice; D009119:Muscle Contraction; D018485:Muscle Fibers, Skeletal / Q000378:metabolism; D018482:Muscle, Skeletal / Q000294:innervation / Q000378:metabolism* / Q000503:physiopathology; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism; D009211:Myoglobin / Q000235:genetics / Q000378:metabolism*; D050778:NFATC Transcription Factors / Q000378:metabolism; D011401:Promoter Regions, Genetic; D019837:Ryanodine Receptor Calcium Release Channel / Q000378:metabolism; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D013997:Time Factors; D015533:Transcriptional Activation; D015854:Up-Regulation
chemical_list: D020746:Calcium Channels, L-Type; D009211:Myoglobin; D050778:NFATC Transcription Factors; D019837:Ryanodine Receptor Calcium Release Channel; D019703:Calcineurin