The aac(6')Ib gene in Proteus mirabilis strains resistant to aminoglycosides.
The aim of this study was to evaluate the presence of aac(6')-Ib gene conferring resistance to aminoglycosides in Proteus mirabilis strains. Five isolates had aac(6')-Ib gene. In one case the gene was no-expressed. Three isolates were resistant to all aminoglycosides and minimum inhibitory concentrations were > or = 256 microg/ml. Additionally, all positive strains were resistant to tetracycline and ciprofloxacin.
Wieczorek
Piotr
P
Department of Microbiological Diagnostics, Medical University of Bialystok, Poland. piowie@umwb.edu.pl
Sacha
Paweł
P
Hauschild
Tomasz
T
Ostas
Alina
A
Kłosowska
Wioletta
W
Ratajczak
Jerzy
J
Tryniszewska
Elzbieta
E
D000617:Aminoglycosides / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000187:drug effects* / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D005798:Genes, Bacterial; D016133:Polymerase Chain Reaction; D011513:Proteus mirabilis / Q000187:drug effects* / Q000235:genetics*
D000617:Aminoglycosides