Validity and reliability of the Portuguese-Brazilian version of the Quality of Life in Epilepsy Inventory-89.
OBJECTIVE
The purpose of this article was to report the translation of the Quality of Life in Epilepsy Inventory-89 (QOLIE-89) into a Portuguese-Brazilian version and evaluate its reliability and validity.


METHODS
This study involved 105 outpatients: 54 patients with refractory temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and 51 with juvenile myoclonic epilepsy (JME). Reliability and test-retest reliability were assessed. Relationships between QOLIE-89 domains and other questionnaires (Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, Neuropsychological Evaluation), and external measures such as demographic and clinical variables were analyzed to examine construct validity.


RESULTS
Internal consistency (Cronbach's alpha=0.73-0.92) and test-retest reliability (intraclass correlation coefficient=0.60-0.84) for individual domains were acceptable. For construct validity, we verified high correlations between the QOLIE-89 and the Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, and Neuropsychological Evaluation. For clinical characteristics, the patients with juvenile myoclonic epilepsy had better quality-of-life scores on 11 of 17 QOLIE-89 subscales compared with patients with temporal lobe epilepsy (P<0.05).


CONCLUSIONS
These results support the reliability and validity of the Portuguese-Brazilian translation of QOLIE-89.
Azevedo
Auro Mauro
AM
Department of Neurology, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
Alonso
Neide Barreira
NB
Vidal-Dourado
Marcos
M
Noffs
Maria Helena da Silva
MH
Pascalicchio
Tatiana Frascarelli
TF
Caboclo
Luís Otávio Sales Ferreira
LO
Ciconelli
Rozana Mesquita
RM
Sakamoto
Américo Ceiki
AC
Yacubian
Elza Márcia Targas
EM
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D001938:Brazil; D003071:Cognition / Q000502:physiology; D003863:Depression / Q000209:etiology / Q000523:psychology; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology* / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000523:psychology; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D020190:Myoclonic Epilepsy, Juvenile / Q000523:psychology; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures; D011174:Portugal; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D015203:Reproducibility of Results; D012640:Seizures / Q000453:epidemiology; D012934:Social Isolation; D012944:Social Support; D012959:Socioeconomic Factors
D000927:Anticonvulsants