Congenital herpes simplex virus infection: two unique cutaneous presentations associated with probable intrauterine transmission.
Cutaneous manifestations of congenital herpes simplex virus (HSV) have been classically described as grouped vesicles on an erythematous base. We report two cases of HSV infection wherein both infants presented at birth with widespread erosions and an absence of vesicles or vesicopustules. The presence of skin lesions at birth, neurologic changes seen on radiographic imaging, and a cesarean section delivery in one case suggests intrauterine transmission in both neonates.
Koch
Laine H
LH
Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA.
Fisher
Randall G
RG
Chen
Catherine
C
Foster
Maura M
MM
Bass
W Thomas
WT
Williams
Judith V
JV
D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006561:Herpes Simplex / Q000151:congenital / Q000473:pathology* / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009336:Necrosis; D012867:Skin / Q000473:pathology*