title: New neolignan component from Camellia amplexicaulis and effects on osteoblast differentiation.
abstract: A new neolignan named "camellioside A" (1) has been isolated from the leaves and branches of Camellia amplexicaulis, along with seven known glycosides (2-8). Their structures were determined by a variety of spectroscopic analyses. Among them, compounds 2, 3, 4, and 6 significantly (p<0.05) increased the alkaline phosphatase activity and the mineralization of the nodules of the MC3T3-E1 osteoblastic cells compared to those of the control.
authors.affiliation: College of Pharmacy, Chungnam National University, Daejeon, Korea.
authors.forename: Nguyen Huu
authors.initials: NH
authors.lastname: Tung
authors.forename: Yan
authors.initials: Y
authors.lastname: Ding
authors.forename: Eun Mi
authors.initials: EM
authors.lastname: Choi
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
mesh_terms: D000818:Animals; D028244:Camellia; D002454:Cell Differentiation; D002460:Cell Line; D017705:Lignans / Q000737:chemistry / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D015394:Molecular Structure; D010006:Osteoblasts / Q000187:drug effects*; D010012:Osteogenesis / Q000187:drug effects; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D017705:Lignans; D010936:Plant Extracts; C539585:camellioside A