[Effect of TCM therapy for invigorating Pi, soothing Gan, eliminating dampness and resolving blood stasis on the short-term quality of life in patients with diarrhea type irritable bowel syndrome].
OBJECTIVE
To observe the TCM therapy for invigorating Pi, soothing Gan, eliminating dampness and resolving blood stasis (TCM-T) on the short-term quality of life (stQOL) in patients with diarrhea type irritable bowel syndrome (IBS-D).


METHODS
One hundred and twenty-five patients with IBS-D were assigned to 3 groups, Group A was treated with TCM-T; Group B treated with some selected Chinese patent drugs according to patients' syndrome types, such as Changweikang granule, Guben Yichang tablet, Bupi Yichang pill and Shenling Baizhu pill, Group C treated with Western medicines as Dicetel 50 mg, Oryzanol 10 mg, and Bifid triple viable 420 mg, 3 times daily by oral administration. The therapeutic course was 4 weeks for all. The stQOL was evaluated and compared by SF-36 scale before and after treatment.


RESULTS
Comparison between groups on the scores for the 8 dimensions of SF-36 scale, i.e., physiological function (PF), role physical (RP), body pain (BP), global health (GH), vitality (VT), society function (SF), emotional effect (RE), and mental health (MH), showed no significant difference before treatment, but scores of all the 8 dimensions were improved significantly in Group A after treatment (P < 0.05), with scores of SF, BP, GH and MH superior to those in Group B (P < 0.05, P < 0.01), and scores of RP, GH, SF, RE, PF and MH superior to those in Group C (P < 0.05, P < 0.01).


CONCLUSIONS
TCM-T has favorable effect in treating IBS-D, it could improve the stQOL of patients.
Wu
Bing
B
Beijing TCM Hospital Affiliated to Capital Medical University, Beijing.
Zhang
Sheng-Sheng
SS
D000293:Adolescent; D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D008099:Liver / Q000187:drug effects / Q000503:physiopathology*; D008297:Male; D008516:Medicine, Chinese Traditional; D008603:Mental Health; D008875:Middle Aged; D011788:Quality of Life; D013154:Spleen / Q000187:drug effects / Q000503:physiopathology*; D016896:Treatment Outcome; D055815:Young Adult
D004365:Drugs, Chinese Herbal