Myocardial effects of PDE5 inhibition: more function with less mass.
Semigran
Marc
M
Cardiology Division, Massachusetts General Hospital, Boston, MA 02114, USA. msemigran@partners.org
D000818:Animals; D002118:Calcium / Q000378:metabolism; D004195:Disease Models, Animal; D015870:Gene Expression; D006321:Heart / Q000187:drug effects*; D006801:Humans; D009206:Myocardium / Q000378:metabolism*; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology*; D010879:Piperazines / Q000494:pharmacology; D011687:Purines / Q000494:pharmacology; D053498:Sarcoplasmic Reticulum Calcium-Transporting ATPases / Q000378:metabolism*; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000494:pharmacology; D020257:Ventricular Remodeling
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate; D053498:Sarcoplasmic Reticulum Calcium-Transporting ATPases; D002118:Calcium