Fulminant eosinophilic myocarditis associated with visceral larva migrans caused by Toxocara canis infection.
A 19-year-old man was transferred to hospital because of myocarditis with cardiogenic shock. Echocardiography showed a left ventricular ejection fraction of 23.8% and an intermediate amount of pericardial effusion. The patient immediately received an intra-aortic balloon pump and percutaneous cardiopulmonary support. Right ventricular endomyocardial biopsy was performed in the acute phase and showed extensive eosinophilic inflammatory cell infiltration, severe interstitial edema and moderate myocardial necrosis. High-dose corticosteroids were administered. Because the patient's antibody titer against Toxocara canis was high and his symptoms had appeared after eating raw deer meat, the diagnosis was fulminant eosinophilic myocarditis caused by a hypersensitivity reaction to visceral larval migrans. After starting high-dose corticosteroids, the ejection fraction dramatically improved, the eosinophilia decreased and the patient made a full recovery.
Enko
Kenki
K
Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama, Japan.
Tada
Takeshi
T
Ohgo
Keiko O
KO
Nagase
Satoshi
S
Nakamura
Kazufumi
K
Ohta
Kei
K
Ichiba
Shingo
S
Ujike
Yoshihito
Y
Nawa
Yukifumi
Y
Maruyama
Haruhiko
H
Ohe
Tohru
T
Kusano
Kengo F
KF
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D006801:Humans; D007816:Larva Migrans, Visceral / Q000175:diagnosis* / Q000469:parasitology*; D008297:Male; D009205:Myocarditis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D017166:Toxocara canis; D014120:Toxocariasis / Q000150:complications* / Q000175:diagnosis*; D016896:Treatment Outcome; D055815:Young Adult
D000305:Adrenal Cortex Hormones