[Comparison of drug-eluting and bare metal stents in saphenous vein grafts. Immediate and long-term results].
OBJECTIVE
Drug-eluting stents (DES) reduce the restenosis rate in native vessels. However, results in saphenous vein grafts (SVG) are less clear. The aim of this study was to compare DES and bare metal stents (BMS) in de novo stenosis in SVG.


METHODS
The study included all percutaneous interventions involving a DES in SVG carried out at five centers up until July 2007. Findings were compared with those in a historical cohort that used conventional stents at two centers. The study analyzed in-hospital and long-term outcomes and predictors of survival and revascularization.


RESULTS
The study included 107 stenoses treated with DESs in 98 patients and 130 stenoses treated with BMS in 113 patients. The DES group was older at baseline and had thrombus less often. There were also procedural differences: in the DES group, stents were longer, direct stenting was used less, and the stent diameter was smaller. The proportion of patients who experienced cardiac death by 12, 24 and 30 months was 95%+/-2%, 91%+/-3% and 89%+/-3%, respectively, in the DES group and 95%+/-2%, 90%+/-3% and 87%+/-3% in the BMS group (P=.66). The proportion without target vessel revascularization at 12, 24 and 30 months was 90%+/-3%, 86%+/-4% and 83%+/-4%, respectively, in the DES group and 94%+/-2%, 87%+/-3% and 87%+/-3% in the BMS group (P=.49). The only predictor of cardiac death was the ejection fraction. There was no predictor of revascularization.


CONCLUSIONS
In our series, using DESs in SVGs was not associated with a reduction in mortality or target vessel revascularization. The only predictor of cardiac death was the ejection fraction. There was no predictor of revascularization.
Lozano
Iñigo
I
Servicio de Cardiología, Hospital Central de Asturias, Oviedo, Asturias, Spain. imlml9@hotmail.com
García-Camarero
Tamara
T
Carrillo
Pilar
P
Baz
José A
JA
de la Torre
José M
JM
López-Palop
Ramón
R
Pinar
Eduardo
E
Salvatella
Neus
N
Avanzas
Pablo
P
Valdés
Mariano
M
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002423:Cause of Death; D015331:Cohort Studies; D001026:Coronary Artery Bypass; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests; D012501:Saphenous Vein / Q000637:transplantation*; D015607:Stents; D013534:Survival; D016896:Treatment Outcome