title: X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.
abstract: Racemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a.
authors.affiliation: Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, USA.
authors.forename: Kalyaneswar
authors.initials: K
authors.lastname: Mandal
authors.forename: Brad L
authors.initials: BL
authors.lastname: Pentelute
authors.forename: Valentina
authors.initials: V
authors.lastname: Tereshko
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Kossiakoff
authors.forename: Stephen B H
authors.initials: SB
authors.lastname: Kent
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D011489:Protein Denaturation; D017434:Protein Structure, Tertiary; D012604:Scorpion Venoms / Q000737:chemistry*; D012605:Scorpions / Q000737:chemistry*
chemical_list: C490373:BKTx1 protein, Buthus martensi; D012604:Scorpion Venoms