title: Cell proliferation induction: healing chronic wounds through low-energy pulsed radiofrequency.
abstract: Chronic lower extremity wounds are a major source of morbidity and health care expenditure across the world. In the last decade, numerous advanced modalities have become available that can help expedite wound healing when standard wound care modalities are unsuccessful. In this case report, the authors present their early experience with one such modality that uses pulsed radiofrequency energy to initiate cell proliferation induction in chronic lower extremity wounds of different etiologies that had failed to respond to standard therapy.
authors.affiliation: Carl T. Hayden VA Medical Center, Phoenix, Arizona 85268, USA. Robert.frykberg@va.gov
authors.forename: Robert
authors.initials: R
authors.lastname: Frykberg
authors.forename: Edward
authors.initials: E
authors.lastname: Tierney
authors.forename: Arthur
authors.initials: A
authors.lastname: Tallis
authors.forename: Tosha
authors.initials: T
authors.lastname: Klotzbach
mesh_terms: D000368:Aged; D049109:Cell Proliferation / Q000528:radiation effects*; D002908:Chronic Disease; D006801:Humans; D007871:Leg Ulcer / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D000078702:Radiofrequency Therapy; D012074:Remission Induction / Q000379:methods; D017592:Skin Care / Q000295:instrumentation* / Q000379:methods*; D014945:Wound Healing / Q000528:radiation effects*