title: Genomic research for important pathogenic bacteria in China.
abstract: Rapid accumulation of bacterial genomic data offered an unprecedented opportunity to understand bacterial biology from a holistic view of point. We can thus closely look at the way in which a pathogen is evolved, and these data has been applied to molecular epidemiology and microbial forensics, and screening of novel diagnostic, vaccine and drug targets. The newly developed high-throughput low-cost sequencing technologies, such as 454, Solexa and SOLiD, will promote the acquisition and application of genomic data in new research areas that we dared not imagine previously, such as the metagenomics of human gastric-intestinal tract, for better and comprehensive understanding of human health and disease.
authors.affiliation: Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China. ruifuyang@gmail.com
authors.forename: RuiFu
authors.initials: R
authors.lastname: Yang
authors.forename: XiaoKui
authors.initials: X
authors.lastname: Guo
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: YongQiang
authors.initials: Y
authors.lastname: Jiang
authors.forename: Bo
authors.initials: B
authors.lastname: Pang
authors.forename: Chen
authors.initials: C
authors.lastname: Chen
authors.forename: YuFeng
authors.initials: Y
authors.lastname: Yao
authors.forename: JinHong
authors.initials: J
authors.lastname: Qin
authors.forename: QingTian
authors.initials: Q
authors.lastname: Li
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D001428:Bacterial Vaccines / Q000276:immunology; D035843:Biomedical Research / Q000379:methods*; D002681:China / Q000453:epidemiology; D016680:Genome, Bacterial / Q000235:genetics*; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D001428:Bacterial Vaccines