Can plastic tracheotomy tubes harm baby boys?
Pediatric tracheotomy tubes are often made from polyvinyl chloride (PVC). Di(2-ethylhexyl) phthalate (DEHP) is a common additive to PVC to increase tracheotomy tube flexibility and strength. Unfortunately, DEHP is a reproductive toxicant that alters the male reproductive system in animals, in vitro tests, and limited human data. DEHP leaches from PVC tracheotomy tubes in children. The FDA and multiple international health agencies urge health care professionals to use DEHP-free medical materials for vulnerable patients, especially the male infant. The observed toxicity of DEHP and the readily available alternative materials to PVC tracheotomy tubes present a compelling argument to use pediatric tracheotomy tubes made from non-PVC materials such as polyurethane or silicone. More clinical research is needed.
Mair
Asa A
AA
University of North Carolina, Chapel Hill, NC, USA.
Mair
Eric A
EA
D004051:Diethylhexyl Phthalate / Q000633:toxicity*; D005837:Genitalia, Male / Q000187:drug effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014140:Tracheotomy / Q000295:instrumentation*
D004051:Diethylhexyl Phthalate