title: New cerebrosides from a marine sponge Haliclona (Reniera) sp.
abstract: A chemical investigation of the MeOH extract of a marine sponge Haliclona (Reniera) sp., collected off the coast of Ulleung Island, Korea, led to the isolation of thirteen new cerebrosides (1--3, 5--14), along with a known analogue (4). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy, MS spectrometry, and chemical method. The major new features of these glucocerebrosides are C15 and C19 acyl chains, long (C24-C28) acyl chains, or the S-configuration of the acyl chains. It is noteworthy that both R- and S-configurations of the acyl chains were observed in the same specimen.
authors.affiliation: College of Pharmacy, Pusan National University, Busan, Korea.
authors.forename: Taeseong
authors.initials: T
authors.lastname: Park
authors.forename: Tayyab Ahmad
authors.initials: TA
authors.lastname: Mansoor
authors.forename: Pramod Bapurao
authors.initials: PB
authors.lastname: Shinde
authors.forename: Baoquan
authors.initials: B
authors.lastname: Bao
authors.forename: Jongki
authors.initials: J
authors.lastname: Hong
authors.forename: Jee Hyung
authors.initials: JH
authors.lastname: Jung
mesh_terms: D000818:Animals; D002554:Cerebrosides / Q000737:chemistry* / Q000302:isolation & purification*; D047129:Haliclona / Q000737:chemistry*; D007723:Korea; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D002554:Cerebrosides; D000432:Methanol