title: Myoepithelioma of soft tissue.
abstract: Myoepitheliomas and mixed tumors involving deep subcutaneous and subfascial soft tissues of limb or limb girdle are rare lesions as against salivary lesions that are well established conditions. Here, we report a 22-year-old female who presented with painful hard swelling in the left gluteal region of 1(1/2) year duration. MRI showed a large ill-defined heterogeneous mass lesion measuring about 7-8 cm. in the left sacral region eroding the left sacroiliac region and left sacroiliac joint. With a clinical diagnosis of chondrosarcoma, the tumor with the surrounding tissue was resected in segments at surgery. Histomorphology revealed nests, sheets and cords of round to spindled cells with extensive squamous metaplasia in a myxoid to fibrous stroma. These cells extensively infiltrated muscle and bone. The tumor cells expressed immunoreactivity for cytokeratin (AE1/AE3) and S-100.
authors.affiliation: Department of Pathology, Kasturba Medical College, Mangalore - 575 001, Karnataka, India. paimuktha@yahoo.com
authors.forename: Mukhta R
authors.initials: MR
authors.lastname: Pai
authors.forename: Ramadas
authors.initials: R
authors.lastname: Naik
authors.forename: Ramachandra
authors.initials: R
authors.lastname: Kamath
authors.forename: Dilasma
authors.initials: D
authors.lastname: Magar
mesh_terms: D000328:Adult; D002081:Buttocks / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D008279:Magnetic Resonance Imaging; D009208:Myoepithelioma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D012446:Sacroiliac Joint / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery
chemical_list: D007633:Keratins