title: On the role of cell signaling models in cancer research.
abstract: The main objective of this review is to emphasize the role and importance of the careful mathematical/computational modeling of signaling networks for the understanding of aberrant signaling in cancer and for the development of targeted therapies.
authors.affiliation: University of Michigan, Ann Arbor, Michigan 48109, USA.
authors.forename: Alejandra C
authors.initials: AC
authors.lastname: Ventura
authors.forename: Trachette L
authors.initials: TL
authors.lastname: Jackson
authors.forename: Sofia D
authors.initials: SD
authors.lastname: Merajver
mesh_terms: D008954:Models, Biological; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D015398:Signal Transduction