title: Metabolites from the biodegradation of 1,6-hexanediol dibenzoate, a potential green plasticizer, by Rhodococcus rhodochrous.
abstract: Metabolites from the biodegradation of a potential plasticizer 1,6-hexanediol dibenzoate in the presence of n-hexadecane as a co-substrate by the common soil organism Rhodococcus rhodochrous were identified using GC/MS and Fourier transform mass spectroscopy (FTMS) techniques. Trimethylsilylation of compounds from the biodegradation broth permitted detection of the following metabolites: 1-hexadecyl benzoate, 6-benzoyloxyhexanoic acid, 4-benzoyloxybutanoic acid, 6-benzoyloxyhexan-1-ol and benzoic acid. The presence of these metabolites was confirmed by repeating the biodegradation with 1,6-hexanediol di[(2)H(5)]benzoate, by measurement of their exact masses in FTMS and by comparison with available authentic materials. The results show that biodegradation of 1,6-hexanediol dibenzoate by R. rhodochrous does not lead to the accumulation of persistent metabolites as has been reported for commercial dibenzoate plasticizers.
authors.affiliation: Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, QC, Canada H3A 2B2.
authors.forename: Azadeh Kermanshahi
authors.initials: AK
authors.lastname: Pour
authors.forename: Orval A
authors.initials: OA
authors.lastname: Mamer
authors.forename: David G
authors.initials: DG
authors.lastname: Cooper
authors.forename: Milan
authors.initials: M
authors.lastname: Maric
authors.forename: Jim A
authors.initials: JA
authors.lastname: Nicell
mesh_terms: D001565:Benzoates / Q000737:chemistry / Q000378:metabolism*; D001673:Biodegradation, Environmental; D005583:Fourier Analysis; D008401:Gas Chromatography-Mass Spectrometry; D055772:Green Chemistry Technology / Q000379:methods; D013058:Mass Spectrometry; D019906:Nuclear Magnetic Resonance, Biomolecular; D010968:Plasticizers / Q000737:chemistry / Q000378:metabolism*; D012240:Rhodococcus / Q000378:metabolism*
chemical_list: C542277:1,6-hexanediol dibenzoate; D001565:Benzoates; D010968:Plasticizers