Visuomotor priming effects in Parkinson's disease patients depend on the match between the observed and the executed action.
Evidence exists that action observation activates the same cortical motor areas that are involved in the performance of the observed actions. An untested idea is whether subcortical structures such as the basal ganglia play a role in the coding of other people's actions. This study used kinematics to examine how Parkinson's disease patients react to the observation of an action which they were subsequently requested to perform. In each trial a model and an observer, which could be either a Parkinsonian patient or a neurologically healthy participant, were seated facing each other. The model was requested to grasp a stimulus (action condition), to perform a kicking action towards the stimulus (control-action condition), and to not perform any action (control condition). The task for the observer was always to grasp the stimulus after having watched the model performing her task. Results show that Parkinson's disease patients did show facilitation effects only when the model was a Parkinsonian patient. Whereas, neurologically healthy participants' movements were facilitated following the observation of either the Parkinsonian and the healthy model grasping the object. No facilitation effects were found for both the control and the control-action conditions. The fact that normal visuomotor priming takes place in PD patients when the observed action matches with what they can perform suggests that basal ganglia might not be necessary for it. However, damage to the basal ganglia might become relevant when such a match does not occur. In such circumstances, a damage to these structures might prevent the deployment of additional activity which might be necessary to influence cortical functions related to the representations of observed actions.
Castiello
Umberto
U
Dipartimento di Psicologia Generale, Università di Padova, Via Venezia 8, 35131 Padova, Italy. umberto.castiello@unipd.it
Ansuini
Caterina
C
Bulgheroni
Maria
M
Scaravilli
Tomaso
T
Nicoletti
Roberto
R
D001479:Basal Ganglia / Q000503:physiopathology*; D001696:Biomechanical Phenomena; D003071:Cognition; D005260:Female; D007839:Functional Laterality; D018737:Hand Strength; D006801:Humans; D007100:Imitative Behavior; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000503:physiopathology / Q000523:psychology*; D011597:Psychomotor Performance; D014796:Visual Perception