title: Evaluation of erectile function after urethral reconstruction: a prospective study.
abstract: We conducted a prospective study of erectile dysfunction (ED) after urethral reconstructive surgery, using the 5-item International Index of Erectile Function (IIEF-5), the Sexual Life Quality Questionnaire (SLQQ) and the Quality of Life Questionnaire (QoLQ). Between January 2003 and July 2007, 125 male patients with urethral strictures underwent urethroplasty, and pre- and post-surgery erectile function was assessed using these three questionnaires. A formula to predict the probability of ED after urethroplasty was derived. At 3 months post-operatively, there was a significant decrease in IIEF-5 (16.57 +/- 7.98) and SLQQ scores (28.71 +/- 14.84) compared with pre-operative scores (P < 0.05). However, the IIEF-5 scores rebounded at 6 months post-operatively (17.22 +/- 8.41). Logistical regression analysis showed that the location of the urethral stricture, the recurrence of strictures and the choice of surgical technique were predictive of the post-operative occurrence of ED. This study identified the clinical risk factors for ED after urethroplasty. Posterior urethral stricture and end-to-end anastomosis were found to have a strong relationship with erectile function. The logistical model derived in this study may be applied to clinical decision algorithms for patients with urethral strictures.
authors.affiliation: Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Xie
authors.forename: Yue-Min
authors.initials: YM
authors.lastname: Xu
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Xu
authors.forename: Yin-Long
authors.initials: YL
authors.lastname: Sa
authors.forename: Deng-Long
authors.initials: DL
authors.lastname: Wu
authors.forename: Xin-Chi
authors.initials: XC
authors.lastname: Zhang
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000503:physiopathology; D011446:Prospective Studies; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000009:adverse effects*; D016353:Self-Examination; D011795:Surveys and Questionnaires; D014521:Urethra / Q000473:pathology / Q000601:surgery*; D014525:Urethral Stricture / Q000473:pathology / Q000601:surgery