Development and evaluation of a computerized test battery for Alzheimer's disease screening in community-based settings.
OBJECTIVE
To evaluate the capability of a computerized test battery for Alzheimer's disease screening which has been newly developed to provide a standardized and efficient method for widespread use in routine clinical and community-based settings.


METHODS
Participants were 72 individuals diagnosed with Alzheimer's disease and 102 healthy elderly individuals. Both groups were tested by the battery. Receiver operating characteristic analysis was used to examine the ability of the battery to differentiate between those with Alzheimer's disease and cognitively healthy elderly individuals.


RESULTS
On a group level, the Alzheimer's disease group performed worse than the control group on each of the 4 computerized test tasks. Receiver operating characteristic analysis yielded maximum sensitivity and specificity values of 96% and 86% for total scores, respectively.


CONCLUSIONS
We believe the battery is very useful for routine clinical and community-based settings.
Inoue
Masashi
M
Information Media Center, Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, Yonago, Japan. masashi@med.totttori-u.ac.jp
Jinbo
Daiki
D
Nakamura
Yuka
Y
Taniguchi
Miyako
M
Urakami
Katsuya
K
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis*; D003071:Cognition; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000592:standards*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods* / Q000592:standards*; D012372:ROC Curve; D015203:Reproducibility of Results; D012111:Residence Characteristics; D012680:Sensitivity and Specificity