title: [Anthropometric measures: predictors of non-transmissible chronic diseases in postmenopausal women in the Southeast region of Brazil].
abstract: OBJECTIVE
  to evaluate the anthropometric measures as predictors of cardiovascular and metabolic risk in non-transmissible chronic diseases in postmenopausal women.
  
  
  METHODS
  a clinical and sectional study enrolling 120 sedentary postmenopausal women (amenorrhea for at least 12 months, age 45 to 70 years was conducted). Exclusion criteria included insulin-dependent diabetes and use of statins or hormone therapy within the preceding six months. Anthropometric indicators included: weight, height, body mass index (BMI=weight/height(2)), and waist circumference (WC). Metabolic profiles as total cholesterol (TC), HDL, LDL, triglycerides (TG), glycemia, and insulin were measured and the atherogenic index of plasma (AIP) and Homeostasis model assessment-insulin resistance (HOMA-IR) were calculated. One-way analysis of variance (ANOVA) and Odds Ratio (OR) were used in the statistical analysis.
  
  
  RESULTS
  subjects were classified on average as overweight and showed central fat distribution. Overweight and obesity were observed in 76% and abdominal obesity in 87.3% of the patients. On average, TC, LDL and TG levels were higher than recommended in 67.8, 55.9 and 45.8% of the women, respectively, and HDL was low in 40.7%. Values of WC >88 cm were observed in 14.8% of women with normal weight, 62.5% overweight and 100% obesity p>0.05). On average, the values of AIP, TG, and HOMA-IR increased significantly along with values of BMI and WC, while decreased HDL (p<0.05). Among women with WC >88 cm, a risk association was observed with low HDL (OR=5.86; 95%CI=2.31-14.82), with higher TG (OR=2.61; 95%CI=1.18-5.78), with higher AIP (OR=3.42; 95%CI=1.19-9.78) and with IR (OR=3.63; 95%CI=1.27-10.36). There was a risk of low HDL (OR=3.1; 95%CI=1.44-6.85) with increased obesity (BMI>30 kg/m(2)).
  
  
  CONCLUSIONS
  in the postmenopausal women, the simple measure of WC can predict cardiovascular and metabolic risk of non-transmissible chronic diseases.
authors.affiliation: Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brazil.
authors.forename: Fábio Lera
authors.initials: FL
authors.lastname: Orsatti
authors.forename: Eliana Aguiar Petri
authors.initials: EA
authors.lastname: Nahas
authors.forename: Jorge
authors.initials: J
authors.lastname: Nahas-Neto
authors.forename: Nailza
authors.initials: N
authors.lastname: Maestá
authors.forename: Nathália Pompeu
authors.initials: NP
authors.lastname: Padoani
authors.forename: Cláudio Lera
authors.initials: CL
authors.lastname: Orsatti
mesh_terms: D000368:Aged; D000886:Anthropometry; D001938:Brazil; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008659:Metabolic Diseases / Q000453:epidemiology*; D008875:Middle Aged; D017698:Postmenopause; D011379:Prognosis; D012307:Risk Factors