The science behind biomaterials in female stress urinary incontinence surgery.
Female stress urinary incontinence, while not life threatening, can present with various social and economic implications. Biomaterials, primarily synthetic, are often utilized to augment surgical correction. Repair with biomaterials involves midurethral support to function against weakened connective tissue caused by injury, abnormal collagen metabolism, or genetic predisposition. Even though efficacy rates are high, the potential for complications, such as erosion, are great without comprehension of inherent characteristics of each graft material. Low-weight, macroporous, monofilament synthetic grafts and noncross-linked biologic grafts are examples of biomaterials that implant reasonably well with host tissue. This paper reviews the justification for biomaterial use, host reaction, and the various parameters of natural and synthetic grafts.
Amrute
Kaytan V
KV
Jacobi Medical Center, Department of Obstetrics/Gynecology, Bronx, NY 10461, USA. kvamrute@gmail.com
Badlani
Gopal H
GH
D000818:Animals; D001672:Biocompatible Materials; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D005260:Female; D006801:Humans; D019736:Prostheses and Implants; D014550:Urinary Incontinence, Stress / Q000503:physiopathology / Q000601:surgery*
D001672:Biocompatible Materials; D001688:Biological Products