title: Primary laryngeal leishmaniasis: a rare case report.
abstract: Laryngeal leishmaniasis is extremely rare. We report a case of primary laryngeal leishmaniasis in a 70-year-old male who was admitted with complaints of gradual progressive hoarseness of the voice, dyspnea, cough for the past 3 months and noisy breathing for the past 5 days. An X-ray of the soft tissue of the neck showed a prevertebral soft tissue mass causing narrowing of the airway at the C6-C7 vertebral level. A computerized tomography (CT) scan showed a soft tissue mass in the subglottic region causing significant narrowing of the airway. A direct laryngoscopy showed a pinkish-white, friable mass involving the subglottic region and the anterior half of the vocal cords. With the clinical suspicion of malignancy, an endoscopic biopsy was done. A histopathological examination showed diffuse mixed inflammatory cell infiltrate in subepithelium with numerous Leishmania donovani bodies in the cytoplasm of histiocytes.
authors.affiliation: Department of Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. bipinkumar31@yahoo.co.in
authors.forename: Bipin
authors.initials: B
authors.lastname: Kumar
authors.forename: Anand
authors.initials: A
authors.lastname: Ghimire
authors.forename: Smriti
authors.initials: S
authors.lastname: Karki
authors.forename: Paricha
authors.initials: P
authors.lastname: Upadhyaya
mesh_terms: D000818:Animals; D001706:Biopsy; D006801:Humans; D007818:Laryngeal Diseases / Q000469:parasitology*; D007828:Laryngoscopy; D007830:Larynx / Q000473:pathology; D007893:Leishmania donovani / Q000302:isolation & purification*; D007896:Leishmaniasis / Q000175:diagnosis* / Q000469:parasitology; D008297:Male; D009333:Neck / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed