Impedance spectroscopic investigation of the bilayer lipid membranes formed from the phosphatidylserine-ceramide mixture.
Electrochemical impedance spectroscopy was used for the study of two-component lipid membranes. Phosphatidylserine and ceramide were to be investigated because they play an important biochemical role in cell membranes. The research on biolipid interaction was focused on a quantitative description of processes that take part in a bilayer. Assumed models of interaction between amphiphilic molecules and the equilibria that take place there were described by mathematical equations for the studied system. The possibility of complex formation for a two-component system forming bilayers was assumed, which could explain the deviation from the additivity rule. The molecular area and the equilibrium constant of the complex were determined.
Naumowicz
Monika
M
Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443, Bialystok, Poland.
Figaszewski
Zbigniew Artur
ZA
D002518:Ceramides / Q000737:chemistry*; D017097:Electric Impedance; D004563:Electrochemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D008954:Models, Biological; D010718:Phosphatidylserines / Q000737:chemistry*
D002518:Ceramides; D008051:Lipid Bilayers; D010718:Phosphatidylserines