Melioidosis: antibiogram of cases in Singapore 1987-2007.
The antimicrobial susceptibility of Burkholderia pseudomallei isolates identified by the bacteriology laboratory at Singapore General Hospital was reviewed. Laboratory data were found to be available since 1987 and showed that ceftazidime, amoxicillin-clavulanate, chloramphenicol and tetracycline had remained effective through the years. Imipenem was added to the list of antimicrobials tested after 1989, and the isolates showed high susceptibility rates. Co-trimoxazole was found to be useful based on Etest results, but the isolates had low susceptibility rates when tested using disk diffusion.
Tan
Ai Ling
AL
Department of Pathology, Singapore General Hospital, Outram Road, Singapore 169608, Republic of Singapore. tan.ai.ling@sgh.com.sg
Tan
Mee-Lee
ML
D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D016957:Burkholderia pseudomallei / Q000187:drug effects* / Q000302:isolation & purification; D002442:Ceftazidime / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D008554:Melioidosis / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests / Q000379:methods; D012189:Retrospective Studies; D012846:Singapore; D013752:Tetracycline / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D002701:Chloramphenicol; D015378:Imipenem; D019980:Amoxicillin-Potassium Clavulanate Combination; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002442:Ceftazidime; D013752:Tetracycline