title: Viral etiology and incidence associated with acute gastroenteritis in a 5-year survey in Gyeonggi province, South Korea.
abstract: BACKGROUND
  Acute gastroenteritis caused by viruses is one of the leading causes of childhood morbidity.
  
  
  OBJECTIVE
  The incidence and etiology of virus-associated gastroenteritis during 2001-2005 in Gyeonggi province, South Korea was determined.
  
  
  METHODS
  A total of 10,028 stool specimens were analyzed with enzyme immunoassay, reverse transcription-polymerase chain reaction, and nucleotide sequencing. Phylogenetic analysis of genotype sequences was performed for each of four commonly detected viral pathogens.
  
  
  RESULTS
  At least one viral agent was detected in 29.0% (2908 of 10,028) of the stool samples. Among these, rotavirus was most numerous (66.7%) followed by norovirus (12.6%), astrovirus (11.9%), and enteric adenovirus (2.6%). Mixed infections were identified in 180 cases (1.8%). Patients aged 1-5 years had the largest proportion 83.6% (2430 of 2908) of virus-positive stool specimens. Viral-mediated gastroenteritis was most common from December to May. The most prevalent strains of rotavirus, adenovirus, astrovirus, and norovirus were G1 type, type 41, G1 type, and GII-1 type, respectively.
  
  
  CONCLUSIONS
  Our finding showed the diversity of viral causative agents of gastroenteritis and the prevalence of each gastroenteritis-associated viral genotype in South Korea.
authors.affiliation: Gyeonggido Institute of Health and Environment, Suwon, Gyeonggi-do 440-290, South Korea.
authors.forename: Jeong-Weon
authors.initials: JW
authors.lastname: Huh
authors.forename: Woon-Ho
authors.initials: WH
authors.lastname: Kim
authors.forename: Su-Gyeong
authors.initials: SG
authors.lastname: Moon
authors.forename: Jong-Bok
authors.initials: JB
authors.lastname: Lee
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Lim
mesh_terms: D000256:Adenoviridae / Q000235:genetics / Q000302:isolation & purification*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D015994:Incidence; D007223:Infant; D007723:Korea / Q000453:epidemiology; D001257:Mamastrovirus / Q000235:genetics / Q000302:isolation & purification*; D029322:Norovirus / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012401:Rotavirus / Q000235:genetics / Q000302:isolation & purification*; D012621:Seasons; D017422:Sequence Analysis, DNA; D014777:Virus Diseases / Q000175:diagnosis* / Q000453:epidemiology* / Q000821:virology; D055815:Young Adult