title: Recurrent infective endocarditis with uncommon Gram-negative Pasteurella multocida and Pseudomonas aeruginosa: a case report.
abstract: Infective endocarditis (IE) due to Gram-negative bacteria is a rare occurrence, with a relative frequency of less than 10% compared to that caused by Gram-positive bacteria. Herein is presented the fatal case of a 66-year-old man who had undergone mechanical aortic valve replacement 10 years previously, and developed aortic valve IE after sepsis with Pasteurella multocida caused by a cat bite at the left medial ankle. In addition, the patient suffered five months later from mitral and aortic valve endocarditis caused by Pseudomonas aeruginosa. Recurrent surgical therapy was mandatory. This unique case of recurrent Gram-negative IE shows that the condition must still be regarded as complex and often fatal, despite adequate medical and surgical treatment.
authors.affiliation: Department of Cardiology, West-German Heart Center Essen, University of Duisburg-Essen, Germany. nico.reinsch@uk-essen.de
authors.forename: Nico
authors.initials: N
authors.lastname: Reinsch
authors.forename: Björn
authors.initials: B
authors.lastname: Plicht
authors.forename: Alexander
authors.initials: A
authors.lastname: Lind
authors.forename: Rolf A
authors.initials: RA
authors.lastname: Jánosi
authors.forename: Thomas
authors.initials: T
authors.lastname: Buck
authors.forename: Markus
authors.initials: M
authors.lastname: Kamler
authors.forename: Heinz
authors.initials: H
authors.lastname: Jakob
authors.forename: Christoph K
authors.initials: CK
authors.lastname: Naber
authors.forename: Raimund
authors.initials: R
authors.lastname: Erbel
mesh_terms: D000368:Aged; D000818:Animals; D001733:Bites and Stings / Q000150:complications; D002415:Cats; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010326:Pasteurella Infections / Q000175:diagnosis / Q000188:drug therapy; D016979:Pasteurella multocida / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D012008:Recurrence; D012086:Reoperation; D014081:Tooth Extraction / Q000009:adverse effects