Facile, economical and direct synthesis of 9-anilinoacridines.
Acridines are well-known group of compounds with a wide variety of biological properties. We describe herein an expeditious approach to prepare anilinoacridine derivatives from mefenamic acid. It is the first report of a one-pot approach to anilinoacridines in good to excellent yields.
Khan
Khalid M
KM
International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan. hassaan2@super.net.pk
Rao
Nosheen A
NA
Ali
Muhammad
M
Perveen
Shahnaz
S
Choudhary
Muhammad Iqbal
MI
Voelter
Wolfgang
W
D000166:Acridines / Q000138:chemical synthesis* / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques / Q000191:economics / Q000379:methods*; D008528:Mefenamic Acid / Q000737:chemistry*; D015394:Molecular Structure
D000166:Acridines; D008528:Mefenamic Acid