title: [Stability of physical state on compound hawthorn dropping pills].
abstract: OBJECTIVE
  To evaluate the stability of physical state with accelerate test and dropping in process before and after on compound hawthorn dropping pills.
  
  
  METHODS
  Scanning electron microscope, TG-DTA, FT-IR and XRD were used.
  
  
  RESULTS
  The active components presented amorphous, tiny crystal and molecular state in dropping pills, and it had no obvious reaction between PEG 4000 and active components. With time prolonging, a little of active components changed from amorphous state to tiny crystal or molecular state.
  
  
  CONCLUSIONS
  Solid dispersion improved the stability and dissolution of compound hawthorn dropping pills.
authors.affiliation: School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Chen
authors.forename: Jian-Lan
authors.initials: JL
authors.lastname: Jiang
mesh_terms: D027825:Crataegus / Q000737:chemistry*; D004339:Drug Compounding / Q000379:methods; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004365:Drugs, Chinese Herbal