Plasma copper and bone mineral density in osteopenia: an indicator of bone mineral density in osteopenic females.
Copper concentrations in blood plasma have been determined in 25 osteopenic females using inductively coupled plasma-mass spectrometry. A high degree of correlations has been demonstrated between the copper concentrations in plasma and the bone mineral density of the lumbar spine as measured using dual energy X-ray absorptiometry and quantitative computerized tomography. Results clearly indicate the involvement of copper in bone health and osteopenia. It is further suggested that plasma copper might be useful as a cheap and simple method indicative of bone mineral density in osteopenic postmenopausal females.
Chaudhri
M Anwar
MA
Institute of Diagnostic and Interventional Radiology, Klinikum-Nuernberg, Breslauer Strasse 201, Nuernberg, Germany. anwar.chaudhri@gmx.net
Kemmler
W
W
Harsch
Igor
I
Watling
R J
RJ
D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000097:blood* / Q000503:physiopathology*; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D013058:Mass Spectrometry; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed
D003300:Copper