title: A prospective ultrasound biomicroscopy evaluation of changes in anterior segment morphology following laser iridotomy in European eyes.
abstract: OBJECTIVE
  The aim of this study is to quantify changes in anterior segment morphology by the use of ultrasound biomicroscopy (UBM) after Nd:YAG laser iridotomy in primary angle closure (PAC) and PAC glaucoma (PACG) in European eyes.
  
  
  METHODS
  A total of 35 eyes of 28 consecutive patients presenting with PAC or PACG were examined by UBM at presentation, and 1 week after Nd:YAG laser peripheral iridotomy (LPI). Mean age of patients was 63.5+/-14.4 (SD) years. Seventeen patients were females (60%). The trabecular-iris angle (TIA) was measured in the superior, nasal, inferior, and temporal quadrants. Baseline measurements were made under light and dark conditions.
  
  
  METHODS
  UBM measurements of the trabecular-iris angle (TIA) and the angle opening distance (AOD).
  
  
  METHODS
  Consecutive observational case series.
  
  
  RESULTS
  All measurements were made in four quadrants. Before LPI, mean superior TIA was 3.59+/-4.5 degrees (mean+/-SD), nasal TIA was 6.37+/-4.9 degrees , inferior TIA was 9.33+/-7.6 degrees , and temporal TIA was 8.65+/-7.3 degrees in light conditions. After LPI, these values increased, respectively, to 12.58+/-6.9 degrees (P<0.05), 15.40+/-6.8 degrees (P<0.05), 16.37+/-7.4 degrees (P<0.05), and 15.95+/-11.3 degrees (P<0.05), showing a significant widening of the angle in all four quadrants. Superior AOD increased from 0.060+/-0.07 to 0.107+/-0.07 mm (P=0.09). No serious LPI-related complications were encountered.
  
  
  CONCLUSIONS
  Dimensions of the anterior chamber angle can be significantly influenced by Nd:YAG laser iridotomy in narrow angle European eyes. UBM examination is a viable tool for the quantitative evaluation of the anterior chamber angle before and after laser iridotomy.
authors.affiliation: Glaucoma Sector, Ophthalmology Clinic, University of Geneva, Geneva, Switzerland. kawehm@yahoo.com
authors.forename: K
authors.initials: K
authors.lastname: Mansouri
authors.forename: N D
authors.initials: ND
authors.lastname: Burgener
authors.forename: M
authors.initials: M
authors.lastname: Bagnoud
authors.forename: T
authors.initials: T
authors.lastname: Shaarawy
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D032801:Iridectomy / Q000379:methods*; D007498:Iris / Q000473:pathology; D053685:Laser Therapy; D008297:Male; D033401:Microscopy, Acoustic / Q000379:methods; D008875:Middle Aged; D011446:Prospective Studies; D014129:Trabecular Meshwork / Q000473:pathology; D044465:White People