title: Invasive infection with hypermucoviscous Klebsiella pneumoniae: multiple cases presenting to a single emergency department in the United States.
abstract: A distinctive form of community-acquired invasive Klebsiella pneumoniae infection has been well described in Southeast Asia for more than 2 decades. The clinical syndrome includes liver abscess, bacteremia, and metastatic infection. It has recently been linked to a virulent hypermucoviscous K pneumoniae phenotype and to a specific genotype. As of 2008, there were only 2 published cases of invasive infection caused by this strain of K pneumoniae in the United States. We report 4 recent cases presenting to a single public hospital emergency department in northern California, which may signal the emergence of this clinical syndrome in North America.
authors.affiliation: Department of Emergency Medicine, Alameda County Medical Center-Highland Campus, Oakland, CA 94602, USA. bradf_98@yahoo.com
authors.forename: Bradley W
authors.initials: BW
authors.lastname: Frazee
authors.forename: Shandi
authors.initials: S
authors.lastname: Hansen
authors.forename: Larry
authors.initials: L
authors.lastname: Lambert
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002140:California / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000302:isolation & purification / Q000472:pathogenicity*; D008297:Male; D008875:Middle Aged; D010641:Phenotype
chemical_list: D000900:Anti-Bacterial Agents