title: Can MTT be used to quantify the antioxidant activity of plant extracts?
abstract: Antioxidant properties of three different medicinal plant extracts from northern Nigeria were evaluated using the traditional qualitative 2,2, diphenyl-picrylhydrazyl (DPPH) method and a new 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) microdilution method described here. The results were in agreement. It is a simple, rapid and inexpensive method compared with many other methods for determining quantitative antioxidant activity of plant extracts.
authors.affiliation: National Veterinary Research Institute, P.M.B. 01, Vom, Plateau State, Nigeria. muravet2002@yahoo.com
authors.forename: I A
authors.initials: IA
authors.lastname: Muraina
authors.forename: M M
authors.initials: MM
authors.lastname: Suleiman
authors.forename: J N
authors.initials: JN
authors.lastname: Eloff
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D013778:Tetrazolium Salts / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D013778:Tetrazolium Salts; D013844:Thiazoles; C022616:thiazolyl blue