Efficient asymmetric transfer hydrogenation of ketones catalyzed by an iron complex containing a P-N-N-P tetradentate ligand formed by template synthesis.
A distorted iron complex formed by template synthesis is the basis of a very efficient and economical catalyst system for the asymmetric transfer hydrogenation of ketones for the production of valuable enantioenriched alcohols.
Mikhailine
Alexandre
A
Davenport Laboratory, Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.
Lough
Alan J
AJ
Morris
Robert H
RH
D002384:Catalysis; D018360:Crystallography, X-Ray; D006859:Hydrogen / Q000737:chemistry*; D058085:Iron Compounds / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010758:Phosphorus / Q000737:chemistry*; D013237:Stereoisomerism
D058085:Iron Compounds; D007659:Ketones; D008024:Ligands; D010758:Phosphorus; D006859:Hydrogen; D009584:Nitrogen