[Mechanical feedback in morphogenesis and cell differentiation].
The review is concerned with studies of mechanical stresses and mechanical feedbacks on the cellular level. The dependence of responses of cells and embryonic tissues on mechanical stresses and their ability to generate these stresses by themselves have been shown. Regular feedbacks between external (passive) and internal (active) mechanical stresses have been established that are required for the viability of cells, determine the direction of their differentiation, and provide the self-organization of morphogenetic processes. Relevant experimental data, are presented and the models of mechanical feedbacks are discussed.
Belousov
L V
LV
Troshina
T G
TG
Mansurov
A N
AN
D000663:Amphibians / Q000502:physiology; D000818:Animals; D001696:Biomechanical Phenomena; D002454:Cell Differentiation / Q000502:physiology*; D005246:Feedback; D008954:Models, Biological; D009024:Morphogenesis / Q000502:physiology*