Polymer nanoparticles: shape-directed monomer-to-particle synthesis.
Well-defined dumbbell and tripartite organic nanoparticles (30-60 nm) were produced via a one-pot direct synthesis of branched amphiphilic block copolymers, avoiding the need for postsynthesis self-assembly steps. We show the mechanism of dumbbell formation is largely a concerted process of particle growth during polymerization, although data suggest that particle-particle linking also occurs, particularly at higher monomer conversions. Dumbbell particles formed using a disulfide bifunctional initiator lead to cleavable structures, underlining the role of initiator functionality in shape control and the potential for functionality placement. Trifunctional initiators allow the direct one-pot synthesis of "tripartite" clover-leaf shaped nanoparticles which would be difficult to achieve through conventional synthesis/self-assembly/cross-linking strategies.
He
Tao
T
Department of Chemistry and Centre for Materials Discovery, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK.
Adams
Dave J
DJ
Butler
Michael F
MF
Cooper
Andrew I
AI
Rannard
Steve P
SP