The sleeping brain's influence on verbal memory: boosting resistance to interference.
Memories evolve. After learning something new, the brain initiates a complex set of post-learning processing that facilitates recall (i.e., consolidation). Evidence points to sleep as one of the determinants of that change. But whenever a behavioral study of episodic memory shows a benefit of sleep, critics assert that sleep only leads to a temporary shelter from the damaging effects of interference that would otherwise accrue during wakefulness. To evaluate the potentially active role of sleep for verbal memory, we compared memory recall after sleep, with and without interference before testing. We demonstrated that recall performance for verbal memory was greater after sleep than after wakefulness. And when using interference testing, that difference was even more pronounced. By introducing interference after sleep, this study confirms an experimental paradigm that demonstrates the active role of sleep in consolidating memory, and unmasks the large magnitude of that benefit.
Ellenbogen
Jeffrey M
JM
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America. jeffrey_ellenbogen@hms.harvard.edu
Hulbert
Justin C
JC
Jiang
Ying
Y
Stickgold
Robert
R
D000293:Adolescent; D001921:Brain / Q000378:metabolism*; D006801:Humans; D008568:Memory / Q000502:physiology*; D008570:Memory, Short-Term / Q000502:physiology*; D012890:Sleep / Q000502:physiology*; D014706:Verbal Learning; D055815:Young Adult