Metoprolol succinate therapy associated with erythema multiforme.
Metoprolol succinate is a widely used medication for the management of hypertension, heart failure, and angina. We report the case of a 36-year-old woman who developed erythema multiforme after administration of a low dose of this drug. She also presented with pruritic burning pain throughout her body accompanied by chills. While erythema multiforme has been reported with carvedilol, this is the first observation of metoprolol succinate causing this and physicians should be aware of this potential, yet rare, side-effect.
Hong
Jaekyoung A
JA
Department of Internal Medicine, Division of Cardiology,University of Rochester Medical Center, Rochester, NY 14642, USA.
Bisognano
John D
JD
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects*; D000328:Adult; D004892:Erythema Multiforme / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006331:Heart Diseases / Q000188:drug therapy*; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D006919:Hydroxyzine / Q000627:therapeutic use; D008790:Metoprolol / Q000009:adverse effects / Q000031:analogs & derivatives*
D000319:Adrenergic beta-Antagonists; D006634:Histamine H1 Antagonists; D006919:Hydroxyzine; D008790:Metoprolol