title: The influence of peritoneal endometriotic lesions on the generation of endometriosis-related pain and pain reduction after surgical excision.
abstract: OBJECTIVE
  To investigate the influence of different kinds of endometriotic lesions, especially peritoneal endometriotic implants in pain generation and the pain reduction after surgical excision in a prospective study.
  
  
  METHODS
  Fifty-one pre-menopausal patients underwent surgical laparoscopy due to chronic pelvic pain, dysmenorrhoea and/or for ovarian cysts. In 44 patients, endometriosis was diagnosed. The pre- and post-operative pain score was determined using a standardized questionnaire with a visual analogue scale. Patients with peritoneal endometriosis were divided into two different groups depending on their pre-operative pain score: group A had a pain score of 3 or more, while group B a pain score of 2 or less. Patients without peritoneal endometriosis were classified as group C, and patients without endometriosis were classified as group D. The pre- and post-operative pelvic pain and/or dysmenorrhoea was analysed according to the different types of endometriotic lesions.
  
  
  RESULTS
  In groups A and C, the post-operative pain score decreased by at least 2 grades or more (p < 0.0). In group D, the post-operative pain score showed no significant reduction.
  
  
  CONCLUSIONS
  The present study suggests that the surgical excision of endometriotic lesions -- including peritoneal implants -- is an effective treatment of endometriosis-associated pelvic pain and/or dysmenorrhoea.
authors.affiliation: Department of Gynaecology, Endometriosis Research Centre Charité, Charité, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Kaiser
authors.forename: Andreas
authors.initials: A
authors.lastname: Kopf
authors.forename: Christine
authors.initials: C
authors.lastname: Gericke
authors.forename: Julia
authors.initials: J
authors.lastname: Bartley
authors.forename: Sylvia
authors.initials: S
authors.lastname: Mechsner
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004412:Dysmenorrhea / Q000209:etiology / Q000601:surgery*; D004715:Endometriosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D010048:Ovarian Cysts / Q000209:etiology / Q000601:surgery*; D010147:Pain Measurement; D017699:Pelvic Pain / Q000209:etiology / Q000601:surgery*; D010537:Peritoneum; D017697:Premenopause; D011446:Prospective Studies; D016896:Treatment Outcome; D055815:Young Adult