title: Prenatal ultrasonographic findings in "trisomy 13".
abstract: OBJECTIVE
  To evaluate the accuracy of prenatal ultrasonographic diagnosis in fetuses with trisomy 13.
  
  
  METHODS
  The present study consisted of all fetuses diagnosed of trisomy 13 and delivered at Ramathibodi Hospital between 1997 and 2006.
  
  
  RESULTS
  There were 15 cases of trisomy 13. Twelve cases (80.0%) were detected by prenatal ultrasonographic examination, and 3 cases (20.0%) were missed. Mean maternal age was 31.4 years old. Sixty-six percent were diagnosed in 2" trimester (mean 19.4 weeks). The earliest gestational age for detection was 12 weeks 6 days. The most common abnormal ultrasonographic findings were holoprosencephaly (46.7%), and facial defects (40.0%).
  
  
  CONCLUSIONS
  The accuracy of prenatal sonographic diagnosis in trisomy 13 fetuses was 80%. The most sensitive prenatal ultrasonographic findings in trisomy 13 were holoprosencephaly and facial defects.
authors.affiliation: Department of Obstetrics & Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. somsri2005p@yahoo.com
authors.forename: Somsri
authors.initials: S
authors.lastname: Pitukkijronnakorn
authors.forename: Patama
authors.initials: P
authors.lastname: Promsonthi
authors.forename: Panyu
authors.initials: P
authors.lastname: Panburana
authors.forename: Rasig
authors.initials: R
authors.lastname: Rangsiprakarn
authors.forename: Apichart
authors.initials: A
authors.lastname: Chittacharoen
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics*; D005145:Face / Q000002:abnormalities; D005260:Female; D005865:Gestational Age; D016142:Holoprosencephaly / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D011247:Pregnancy; D012307:Risk Factors; D014314:Trisomy / Q000175:diagnosis* / Q000235:genetics; D016216:Ultrasonography, Prenatal / Q000706:statistics & numerical data*