title: Prevention of sudden death in sleep.
abstract: Sudden death in sleep, particularly in the young, is a tragic occurrence that conjures thoughts of wrongdoing and foul play. Despite activation of powerful arousal mechanisms when a threat occurs, massive lesions, sudden insurmountable dysfunctions, or profound toxicities may lead to death. Sudden death in sleep is not always inexplicable or unavoidable, which opens a window of opportunity for its prevention. This review explores predisposing conditions and suspected risk factors of sudden death in sleep with a focus on prevention and management.
authors.affiliation: Department of Neurology, SUNY Upstate Medical University, Syracuse, NY, USA.
authors.forename: Antonio
authors.initials: A
authors.lastname: Culebras
mesh_terms: D000328:Adult; D001143:Arousal; D025063:Chromosome Disorders / Q000503:physiopathology; D002884:Chromosomes, Human, Pair 15; D003645:Death, Sudden / Q000517:prevention & control*; D004827:Epilepsy / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007830:Larynx / Q000503:physiopathology; D019578:Multiple System Atrophy / Q000503:physiopathology; D017286:Polysomnography; D011218:Prader-Willi Syndrome / Q000503:physiopathology; D012307:Risk Factors; D012890:Sleep; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D013398:Sudden Infant Death / Q000517:prevention & control*