title: Synthesis of unprecedented scaffold diversity.
abstract: Building a better library: The synthesis of a library of natural-product-like small molecules with unprecedented scaffold diversity has been reported (see scheme; Ns = nosylate). The library represents a significant advancement in the capability of synthetic chemists to generate structurally diverse and complex small molecules in a rapid manner.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
authors.forename: Warren R J D
authors.initials: WR
authors.lastname: Galloway
authors.forename: Mónica
authors.initials: M
authors.lastname: Diáz-Gavilán
authors.forename: Albert
authors.initials: A
authors.lastname: Isidro-Llobet
authors.forename: David R
authors.initials: DR
authors.lastname: Spring
mesh_terms: D001685:Biological Factors / Q000138:chemical synthesis / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D054852:Small Molecule Libraries
chemical_list: D001685:Biological Factors; D054852:Small Molecule Libraries