Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion.
The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial. In this study, 28 New Zealand white male rabbits were randomly divided into five groups. Group A (n = 8), the control group, underwent a sham operation on the unilateral testis without inducing testicular torsion. In groups B, C, and D (n = 5 each), unilateral testicular torsion was induced, and, after 3, 6 or 24 h, respectively, detorsion was performed. In group E (n = 5), permanent unilateral testicular torsion was applied. Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages: pre-torsion (preopration), immediately post-torsion (postopration), pre-detorsion, immediately post-detorsion, and late-stage post-detorsion (6-12 h post-detorsion in groups B-D) or at a similar time point (15-21 h post-torsion in group E). Time-intensity curves were generated, and the following parameters were derived and analyzed: arrival time, time to peak intensity, peak intensity, and half-time of the descending peak intensity. The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side (P < 0.05), which increased with prolonged testicular torsion of the other testis. This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion.
Chen
Lin
L
Department of Ultrasound, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai 200025, China.
Zhan
Wei-Wei
WW
Shen
Zhou-Jun
ZJ
Rui
Wen-Bin
WB
Lv
Chen
C
Chen
Man
M
Zhou
Jian-Qiao
JQ
Zhou
Ping
P
Zhou
Mi
M
Zhu
Ying
Y
D000818:Animals; D003287:Contrast Media; D004195:Disease Models, Animal; D008297:Male; D011817:Rabbits; D012039:Regional Blood Flow / Q000502:physiology*; D013086:Spermatic Cord Torsion / Q000473:pathology* / Q000503:physiopathology; D013737:Testis / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology*; D014463:Ultrasonography
D003287:Contrast Media