title: The concordance correlation coefficient for repeated measures estimated by variance components.
abstract: The concordance correlation coefficient (CCC) is an index that is commonly used to assess the degree of agreement between observers on measuring a continuous characteristic. Here, a CCC for longitudinal repeated measurements is developed through the appropriate specification of the intraclass correlation coefficient from a variance components linear mixed model. A case example and the results of a simulation study are provided.
authors.affiliation: Biostatistics, Department of Public Health, University of Barcelona, Barcelona, Spain. jlcarrasco@ub.edu
authors.forename: Josep L
authors.initials: JL
authors.lastname: Carrasco
authors.forename: Tonya S
authors.initials: TS
authors.lastname: King
authors.forename: Vernon M
authors.initials: VM
authors.lastname: Chinchilli
mesh_terms: D000465:Algorithms; D000704:Analysis of Variance; D019540:Area Under Curve; D003198:Computer Simulation; D016001:Confidence Intervals; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D016014:Linear Models; D015233:Models, Statistical; D015588:Observer Variation; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism; D010599:Pharmacokinetics
chemical_list: D004364:Pharmaceutical Preparations; D006854:Hydrocortisone