Biomarkers for nononcologic gastrointestinal diseases.
Biomarkers are objectively measured indicators of normal and abnormal biologic processes and may vary with therapeutic interventions. In the area of gastrointestinal diseases, biomarker research is primarily in the area of cancer biology. Little is known about biomarkers in connection with other gastrointestinal disorders. This article reviews biomarker data for nononcologic gastrointestinal processes with a focus on allergic disorders.
Katial
Rohit
R
Department of Medicine, Division of Allergy and Immunology, National Jewish Health, 1400 Jackson Street, J329, Denver, CO 80206, USA. katialr@njc.org
D015415:Biomarkers; D000075906:Chemokine CCL26; D019742:Chemokines, CC / Q000097:blood / Q000276:immunology; D004804:Eosinophils / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D005512:Food Hypersensitivity / Q000097:blood / Q000150:complications / Q000276:immunology; D005767:Gastrointestinal Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D018793:Interleukin-13 / Q000097:blood / Q000276:immunology; D053645:Interleukin-2 Receptor alpha Subunit / Q000276:immunology / Q000378:metabolism; D008407:Mast Cells / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D020780:Matrix Metalloproteinase 9 / Q000276:immunology / Q000652:urine; D016176:T-Lymphocyte Subsets / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D016212:Transforming Growth Factor beta / Q000276:immunology / Q000378:metabolism; D042461:Vascular Endothelial Growth Factor A / Q000097:blood / Q000276:immunology
D015415:Biomarkers; C120429:CCL26 protein, human; D000075906:Chemokine CCL26; D019742:Chemokines, CC; D018793:Interleukin-13; D053645:Interleukin-2 Receptor alpha Subunit; D016212:Transforming Growth Factor beta; D042461:Vascular Endothelial Growth Factor A; D007073:Immunoglobulin E; D020780:Matrix Metalloproteinase 9