title: Upper-extremity deep vein thrombosis in a patient on clozapine therapy carrying the prothrombin G20210A mutation.
abstract: Clozapine treatment for resistant schizophrenic disorders has been associated to venous thromboembolic events. We report the case of a patient who developed upper-extremity deep vein thrombosis just 2 months after starting on clozapine in whom the thrombophilia work-up revealed the presence of the prothrombin G20210A mutation.
authors.affiliation: Department of Clinical Pathology, La Fe University Hospital, Valencia, Spain. vaya_amp@gva.es
authors.forename: Amparo
authors.initials: A
authors.lastname: Vayá
authors.forename: Maria
authors.initials: M
authors.lastname: Lopez
authors.forename: Gema
authors.initials: G
authors.lastname: Plumé
authors.forename: José
authors.initials: J
authors.lastname: Ribes
mesh_terms: D003024:Clozapine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017354:Point Mutation; D011516:Prothrombin / Q000235:genetics; D019851:Thrombophilia / Q000235:genetics; D034941:Upper Extremity; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000235:genetics*
chemical_list: D011516:Prothrombin; D003024:Clozapine