title: [Echovirus 6 associated with exanthematic disease].
abstract: Viral exanthems are a common problem in tropical regions, particularly affecting children. Various skin rashes have been reported in acute infections caused by Enterovirus. Biological samples from a child who presented generalized rashes were sent to the Enteric Virus Laboratory of the Adolfo Lutz Institute for laboratory diagnosis to be performed. A viral sample isolated from RD (human rhabdomyosarcoma cells) was subjected to the polymerase chain reaction and showed a 437-base pair product that was characteristic of the Enterovirus genus. Echovirus 6 (E-6) serotype was identified using the indirect immunofluorescence test. In addition, paired serum samples presented seroconversion to E-6. So far, there have not been any reports of E-6 involvement in exanthematic diseases in Brazil. Thus, the importance of epidemiological surveillance for these diseases and their complications is emphasized.
authors.affiliation: Laboratório de Vírus Entéricos, Serviço de Virologia, Divisão de Biologia Médica, Instituto Adolfo Lutz, São Paulo, SP, Brazil.
authors.forename: Ana Paula de Torres
authors.initials: AP
authors.lastname: Santos
authors.forename: Denise Hage
authors.initials: DH
authors.lastname: Russo
authors.forename: Bráulio Caetano
authors.initials: BC
authors.lastname: Machado
authors.forename: Adriana
authors.initials: A
authors.lastname: Luchs
authors.forename: Maria do Carmo Sampaio Tavares
authors.initials: Mdo C
authors.lastname: Timenetsky
authors.forename: Rita de Cássia Compagnoli
authors.initials: Rde C
authors.lastname: Carmona
mesh_terms: D003937:Diagnosis, Differential; D004458:Echovirus 6, Human / Q000235:genetics / Q000276:immunology; D004769:Enterovirus Infections / Q000175:diagnosis / Q000821:virology*; D005076:Exanthema / Q000821:virology*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007223:Infant; D008297:Male; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D012367:RNA, Viral