Ocular dipping in Creutzfeldt-Jakob disease.
Ocular dipping refers to a slow downward deviation of both eyes followed by a quick return to the midposition after a brief delay. Two patients with rapid neurologic deterioration in Creutzfeldt-Jakob disease (CJD) displayed ocular dipping, which quickly evolved into sustained downgaze deviation. Ocular dipping may thus be a transitional sign in a vertical gaze disturbance.
Jeong
Seong-Hae
SH
Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
Kim
Sang Yun
SY
Park
Seong-Ho
SH
Kim
Ji Soo
JS
D000368:Aged; D000377:Agnosia / Q000209:etiology; D000405:Akinetic Mutism / Q000209:etiology; D001072:Apraxias / Q000209:etiology; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology; D002890:Chromosomes, Human, Pair 20 / Q000235:genetics; D003072:Cognition Disorders / Q000209:etiology; D003342:Corpus Striatum / Q000473:pathology / Q000503:physiopathology; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000473:pathology*; D004252:DNA Mutational Analysis; D003704:Dementia / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging; D018450:Disease Progression; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D015835:Ocular Motility Disorders / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D010468:Perceptual Disorders / Q000209:etiology; D049268:Positron-Emission Tomography