title: Bilateral benign non functional struma ovarii with Pseudo-Meigs' syndrome.
abstract: Bilateral presentation of benign Struma ovarii is rare and has not been reported frequently in published literature. A 70-year-old postmenopausal female presented with progressive ascites, bilateral pleural effusion and elevated CA-125 levels. The contrast-enhanced computed tomography (CECT) of the abdomen and pelvis revealed a heterogenous mass in the left adnexa. These findings were suspicious for an ovarian malignancy. After surgery the diagnosis of non functional, bilateral benign Struma ovarii was made. Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs' syndrome) in 5% of cases. The combination of struma ovarii and elevated CA-125 levels has been reported infrequently. This is a rare case of bilateral benign struma ovarii associated with Pseudo-Meigs' syndrome and elevated CA-125 levels. Surgical excision of the ovarian masses induced immediate resolution of the ascites and pleural effusion and a reduction of the serum CA-125 level.
authors.affiliation: Department of Pathology, Command Hospital (EC) Alipore, Kolkata 700 027, India. yashvandana@gmail.com
authors.forename: Vandana
authors.initials: V
authors.lastname: Rana
authors.forename: V
authors.initials: V
authors.lastname: Srinivas
authors.forename: S
authors.initials: S
authors.lastname: Bandyopadhyay
authors.forename: S K
authors.initials: SK
authors.lastname: Ghosh
authors.forename: Yashpal
authors.initials: Y
authors.lastname: Singh
mesh_terms: D000368:Aged; D018394:CA-125 Antigen / Q000097:blood; D005260:Female; D006801:Humans; D008539:Meigs Syndrome / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D010388:Pelvis / Q000000981:diagnostic imaging; D011860:Radiography, Abdominal; D013330:Struma Ovarii / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D018394:CA-125 Antigen