Computational implications of cooperative plasticity induction at nearby dendritic sites.
Recent studies have revealed that plasticity is not regulated independently at individual synapses but rather that there is cooperativity or associativity between nearby synapses in the dendritic tree of individual cortical pyramidal cells. Here, I summarize experimental results regarding such cooperative plasticity and its underlying mechanisms and consider their computational implications.
Morita
Kenji
K
RIKEN Brain Science Institute, Wako, Japan. morita@brain.riken.jp
D000818:Animals; D003198:Computer Simulation; D003712:Dendrites / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D008959:Models, Neurological; D009473:Neuronal Plasticity; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction