3-Alkylpyridinium alkaloids from the Pacific sponge Haliclona sp.
The analysis of the polar extracts of the Pacific sponge Haliclona sp. yielded new dimeric (1), trimeric (2), and polymeric 3-alkylpyridinium alkaloids. Their isolation and structural elucidation, based on NMR and MS data, are discussed in detail, along with their cytotoxic activity.
Casapullo
Agostino
A
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte don Melillo, 84084 Fisciano, Italy. casapullo@unisa.it
Pinto
Oscar Cobar
OC
Marzocco
Stefania
S
Autore
Giuseppina
G
Riccio
Raffaele
R
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D004354:Drug Screening Assays, Antitumor; D047129:Haliclona / Q000737:chemistry*; D006801:Humans; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010140:Pacific Ocean; D011726:Pyridinium Compounds / Q000737:chemistry / Q000302:isolation & purification*
D000470:Alkaloids; D011726:Pyridinium Compounds