Glimpses of the epigenetic landscape.
In this issue of Cell Stem Cell, Cui et al. (2009) provide snapshots of histone modification maps for two different stages of human blood cell development. Revealing chromatin-state maps in model cell types will provide an important framework in which to consider epigenetic controls at molecular and systematic levels.
Shen
Xiaohua
X
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Orkin
Stuart H
SH
D002454:Cell Differentiation / Q000235:genetics; D002843:Chromatin / Q000235:genetics; D044127:Epigenesis, Genetic; D015894:Genome, Human / Q000235:genetics; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000378:metabolism; D006657:Histones / Q000378:metabolism; D006801:Humans; D008957:Models, Genetic; D039902:Multipotent Stem Cells / Q000166:cytology / Q000378:metabolism
D002843:Chromatin; D006657:Histones