Instantaneous deprotection of tosylamides and esters with SmI(2)/amine/water.
SmI(2)/amine/water mediates instantaneous cleavage of tosyl amides and tosyl esters. Highly hindered, sensitive and functionalized substrates were successfully deprotected in near quantitative yield.
Ankner
Tobias
T
Department of Chemistry, University of Gothenburg, Göteborg, Sweden.
Hilmersson
Göran
G