Parameters of nitrogen metabolism during insulin hypoglycemia in rats with alloxan-induced diabetes.
Hypoglycemic coma caused by insulin injection to rats with alloxan-induced diabetes was accompanied by an increase in the concentrations of urea and uric acid and decrease in the content of free amino acids in blood plasma. Activities of glutamate dehydrogenase, AMP deaminase, glutaminase, ALT, and AST in the liver of experimental animals increased.
Medvedeva
N B
NB
Yaroslavl State Medical Academy, Russia.
Telushkin
P L
PL
Stel'makh
A Yu
AY
D000659:AMP Deaminase / Q000378:metabolism; D000496:Alloxan; D000596:Amino Acids / Q000097:blood*; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D003926:Diabetic Coma / Q000378:metabolism*; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D007003:Hypoglycemia / Q000139:chemically induced / Q000378:metabolism; D007328:Insulin / Q000008:administration & dosage; D008099:Liver / Q000201:enzymology; D008297:Male; D051381:Rats; D014444:Tyrosine Transaminase / Q000378:metabolism; D014508:Urea / Q000097:blood*; D014527:Uric Acid / Q000097:blood*
D000596:Amino Acids; D007328:Insulin; D014527:Uric Acid; D000496:Alloxan; D014508:Urea; D005969:Glutamate Dehydrogenase; D014444:Tyrosine Transaminase; D000659:AMP Deaminase