Wittiorumins A - F, antioxidant diels-alder-type adducts from Morus wittiorum.
Six new Diels-Alder-type adducts, wittiorumins A-F ( 1 - 6) along with the three known compounds chalcomoracin ( 7), mulberrofuran J ( 8), and mongolicin F ( 9), were isolated from the stem bark of Morus wittiorum. Their structures including their absolute configurations were determined on the basis of spectroscopic analysis and chemical methods. Some of the isolated compounds ( 1 - 4) were assayed for their antioxidant activities, among which compounds 1 - 3 were active as antioxidants, with inhibitory ratios of 73.0 %, 82.0 %, and 82.0 %, respectively, at a concentration of 10 ( - 5) M.
Tan
Yong-Xia
YX
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China.
Yan
Ren-Yi
RY
Wang
Hong-Qing
HQ
Chen
Ruo-Yun
RY
Yu
De-Quan
DQ
D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008315:Malondialdehyde / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D018547:Plant Stems
D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts; D008315:Malondialdehyde