title: Hydroxychloroquine-induced hyperpigmentation: a case report.
abstract: The antimalarials are one of the most commonly prescribed drugs in medical practice, for conditions such as rheumatoid arthritis as well as malaria. They are generally well-tolerated and the possible side effects of synthetic antimalarials, though infrequent, are well known. Besides the familiar adverse reactions, a localized mucocutaneous bluish-grey to black discolouration can sometimes be seen with antimalarial drugs. The aim of this report was to draw attention to the localized mucocutaneous bluish-grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature.
authors.affiliation: Department of Rheumatology, Physical Medicine and Rehabilitation, School of Medicine, Akdeniz University, Antalya, Turkey. mamelikoglu@gmail.com
authors.forename: M A
authors.initials: MA
authors.lastname: Melikoglu
authors.forename: M
authors.initials: M
authors.lastname: Melikoglu
authors.forename: U
authors.initials: U
authors.lastname: Gurbuz
authors.forename: B S
authors.initials: BS
authors.lastname: Budak
authors.forename: C
authors.initials: C
authors.lastname: Kacar
mesh_terms: D000962:Antimalarials / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects*; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000188:drug therapy
chemical_list: D000962:Antimalarials; D006886:Hydroxychloroquine