Hydroxychloroquine-induced hyperpigmentation: a case report.
The antimalarials are one of the most commonly prescribed drugs in medical practice, for conditions such as rheumatoid arthritis as well as malaria. They are generally well-tolerated and the possible side effects of synthetic antimalarials, though infrequent, are well known. Besides the familiar adverse reactions, a localized mucocutaneous bluish-grey to black discolouration can sometimes be seen with antimalarial drugs. The aim of this report was to draw attention to the localized mucocutaneous bluish-grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature.
Melikoglu
M A
MA
Department of Rheumatology, Physical Medicine and Rehabilitation, School of Medicine, Akdeniz University, Antalya, Turkey. mamelikoglu@gmail.com
Melikoglu
M
M
Gurbuz
U
U
Budak
B S
BS
Kacar
C
C
D000962:Antimalarials / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects*; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000188:drug therapy
D000962:Antimalarials; D006886:Hydroxychloroquine