title: Fetal acidosis from obstetric interventions during the first vaginal delivery.
abstract: OBJECTIVE
  The aim of this study was to analyze the blood gas values of umbilical cord blood in newborns of first vaginal deliveries with or without obstetric interventions.
  
  
  METHODS
  In a prospective descriptive study conducted during the 6-month period from August 2003 through February 2004 at a university hospital, we analyzed the umbilical cord blood gas results of 80 term newborns delivered vaginally from healthy nulliparous women. Multivariate logistic analysis was used to evaluate the associations between fetal acidosis (pH<7.20) and any obstetric interventions.
  
  
  RESULTS
  The mean of umbilical cord blood arterial pH was 7.26 (standard deviation, 0.072). After controlling for the confounding factors with multivariate logistic regression, fetal acidosis (pH<7.20) was found to be significantly associated with oxytocin augmentation (odds ratio [OR], 16.48; 95% confidence interval [CI], 1.21-226.1) and vacuum extraction (OR, 10.76; 95% CI, 1.025-112.9). In contrast, there was no significant relationship between fetal acidosis with episiotomy (OR, 1.096; 95% CI, 0.07-16.6) or epidural anesthesia (OR, 0.074; 95% CI, 0.003-2.09).
  
  
  CONCLUSIONS
  Oxytocin augmentation and vacuum extraction were significantly related to low cord arterial pH values (pH<7.20), but there were no adverse effects to the newborns of first vaginal deliveries.
authors.affiliation: Department of Obstetrics and Gynecology, Kuang Tien General Hospital, and Department of Obstetrics and Gynecology, and Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
authors.forename: Chi-Feng
authors.initials: CF
authors.lastname: Su
authors.forename: Horng-Jyh
authors.initials: HJ
authors.lastname: Tsai
authors.forename: Che-Cheng
authors.initials: CC
authors.lastname: Huang
authors.forename: Kan-Hung
authors.initials: KH
authors.lastname: Luo
authors.forename: Long-Yau
authors.initials: LY
authors.lastname: Lin
mesh_terms: D000138:Acidosis / Q000097:blood* / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000767:Anesthesia, Epidural / Q000009:adverse effects; D036861:Delivery, Obstetric / Q000009:adverse effects*; D004841:Episiotomy / Q000009:adverse effects; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005865:Gestational Age; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D016015:Logistic Models; D015999:Multivariate Analysis; D010121:Oxytocin / Q000009:adverse effects; D010298:Parity; D011247:Pregnancy; D014469:Umbilical Arteries; D014471:Umbilical Veins; D014620:Vacuum Extraction, Obstetrical / Q000009:adverse effects
chemical_list: D010121:Oxytocin