[Studies on chemical constituents of Illicium simonsii].
OBJECTIVE
To study the chemical constituents from the active fractions against HIV in vitro, a crude ethanolic extract of Illicium simonsii.


METHODS
The compounds were isolated with column chromatography methods. MS and NMR spectroscopic methods were used to determine the structures of the compounds.


RESULTS
Seven compounds were isolated from the active fractions against HIV in vitro of the 90% ethanol extract and their structures were elucidated as (+)-catechin (1), (-)-epicatechin (2), (+)-catechin 3-O-alpha-L-rhamnopyranoside (3), kaempferol 3-O-alpha-L-rhamnopyranoside (4), quercetin 3-O-alpha-L-rhamnopyranoside (5), erigeside C (6) and daucosterol (7).


CONCLUSIONS
Seven compounds were isolated from this plant for the first time, but none of them exhibited active against HIV in vitro. Compounds 3 and 6 were isolated from this genus for the first time.
Shang
Xiao-Ya
XY
Beijing Key Laboratory of Bioactive Substances and Functional Foods, College of Arts & Science of Beijing Union University, Beijing 100083, China.
Guo
Miao-Ru
MR
Zhao
Cong-Wei
CW
Li
Shuai
S
D002392:Catechin / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry; D029523:Illicium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012210:Rhamnose / Q000031:analogs & derivatives / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D006027:Glycosides; D012855:Sitosterols; D000431:Ethanol; D002392:Catechin; D012210:Rhamnose; C011015:lyoniside