title: Interleukin-17A and interleukin-17F: a tale of two cytokines.
abstract: In this issue of Immunity, Ishigame et al. (2009) show that interleukin-17A (IL-17A) mediates autoimmunity whereas both IL-17A and IL-17F are required for mucosal immunity. IL-17A may be more pathologic by inducing proinflammatory cytokines.
authors.affiliation: Children's Hospital of Pittsburgh, Rangos Research Center, Pittsburgh, PA 15201, USA.
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Dubin
authors.forename: Jay K
authors.initials: JK
authors.lastname: Kolls
mesh_terms: D000818:Animals; D015551:Autoimmunity; D006801:Humans; D018928:Immunity, Mucosal; D020381:Interleukin-17 / Q000276:immunology / Q000502:physiology*
chemical_list: D020381:Interleukin-17