title: A new cementless total hip arthroplasty with bioactive titanium porous-coating by alkaline and heat treatment: average 4.8-year results.
abstract: A method has been developed for creating a bioactive coating on titanium by alkaline and heat treatment, and shown that it forms a thin layer of hydroxyapatite (HA) on the surface of implants when soaked in simulated body fluid. A series of 70 cementless primary total hip arthroplasties using this coating technique on a porous titanium surface was performed, and followed up the patients for a mean period of 4.8 years. There were no instances of loosening or revision, or formation of a reactive line on the porous coating. Although radiography just after operation showed a gap between the host bone and the socket in over 70% of cases, all the gaps disappeared within a year, indicating the good osteoconduction provided by the coating. Alkaline-heat treatment of titanium to provide a thin HA coating has several advantages over plasma-spraying, including no degeneration or absorption of the HA coating, simplicity of the manufacturing process, and cost effectiveness. In addition, this method allows homogeneous deposition of bone-like apatite within a porous implant. Although this was a relatively short-term study, treatment that creates a bioactive surface on titanium and titanium alloy implants has considerable promise for clinical application.
authors.affiliation: Department of Orthopaedic Surgery, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. kawanabe@kcgh.gr.jp
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kawanabe
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ise
authors.forename: Koji
authors.initials: K
authors.lastname: Goto
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Akiyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakamura
authors.forename: Ayumi
authors.initials: A
authors.lastname: Kaneuji
authors.forename: Tanzo
authors.initials: T
authors.lastname: Sugimori
authors.forename: Tadami
authors.initials: T
authors.lastname: Matsumoto
mesh_terms: D000328:Adult; D000368:Aged; D000468:Alkalies; D019644:Arthroplasty, Replacement, Hip; D001843:Bone Cements; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D014025:Titanium
chemical_list: D000468:Alkalies; D001843:Bone Cements; D014025:Titanium