title: In vitro comparison of the efficacies of natamycin and silver nitrate against ocular fungi.
abstract: The in vitro activity of the silver nitrate was assessed in comparison with that of natamycin against 128 corneal Fusarium isolates and 90 corneal Aspergillus isolates. MIC(90)s of silver nitrate were 2 microg/ml for Fusarium spp. and 1 microg/ml for Aspergillus spp. MIC(90)s of natamycin were 8 microg/ml for Fusarium spp. and 32 microg/ml for Aspergillus spp. Silver nitrate exhibited potent antifungal activity against ocular fungi in vitro.
authors.affiliation: Department of Ocular Pharmacology, Henan Institute of Ophthalmology, Zhengzhou, China. xuyan990301@yahoo.com.cn
authors.forename: Yan
authors.initials: Y
authors.lastname: Xu
authors.forename: Guangren
authors.initials: G
authors.lastname: Pang
authors.forename: Chuanwen
authors.initials: C
authors.lastname: Gao
authors.forename: Dongqing
authors.initials: D
authors.lastname: Zhao
authors.forename: Lutan
authors.initials: L
authors.lastname: Zhou
authors.forename: Shengtao
authors.initials: S
authors.lastname: Sun
authors.forename: Bingliang
authors.initials: B
authors.lastname: Wang
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects*; D005123:Eye; D015821:Eye Infections, Fungal / Q000382:microbiology*; D005670:Fusarium / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010866:Natamycin / Q000494:pharmacology*; D012835:Silver Nitrate / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D010866:Natamycin; D012835:Silver Nitrate