title: Orthodontic treatment in a patient with cleidocranial dysostosis.
abstract: Cleidocranial dysostosis is a rare congenital skeletal disorder, associated with clavicular hypoplasia or aplasia, delayed closure of cranial fontanels, brachycephalic skull, delayed exfoliation of primary dentition, eruption of permanent teeth, and multiple supernumerary and morphologic abnormalities of the maxilla and mandible. The disorder is caused by mutation in the CBFA1 gene, on the short arm of chromosome 6p21. The prevalence of cleidocranial dysostosis is estimated one per million, without sex or ethnic group predilection. The purpose of this paper is to describe the orthodontic treatment in a patient with cleidocranial dysostosis. Therapy may include removal of supernumerary teeth, surgical exposure of impacted teeth, and orthodontic treatment.
authors.affiliation: Department of Orthodontics, University of Milan, Milan, Italy.
authors.forename: Giampietro
authors.initials: G
authors.lastname: Farronato
authors.forename: Cinzia
authors.initials: C
authors.lastname: Maspero
authors.forename: Davide
authors.initials: D
authors.lastname: Farronato
authors.forename: Silvia
authors.initials: S
authors.lastname: Gioventù
mesh_terms: D000328:Adult; D002973:Cleidocranial Dysplasia / Q000150:complications*; D006801:Humans; D008297:Male; D008313:Malocclusion, Angle Class III / Q000209:etiology; D050793:Orthodontic Extrusion / Q000379:methods*; D014081:Tooth Extraction; D014094:Tooth, Deciduous / Q000601:surgery; D014095:Tooth, Impacted / Q000209:etiology* / Q000628:therapy; D014096:Tooth, Supernumerary / Q000209:etiology* / Q000601:surgery; D014716:Vertical Dimension