Carbonic anhydrase III: the new hope for the elimination of exercise-induced muscle fatigue.
Fatigue, defined as the failure to maintain the required or expected power output, is a complex problem. Its occurrence mechanism is extremely complicated. The obvious reasons are that it is a multifactorial situation and that the limiting factors may vary with force intensity, exercise duration and muscle type. In recent years, it has been found that carbonic anhydrase III(CAIII) which is present in high concentrations in muscles has multiple biological activities that can dissipate or resist some fatigue related substances. Therefore, we hypothesize that the CAIII supplementation may contribute to dissipate fatigue. Confirmation of this hypothesis will further add to our understanding of the physiological functions of CAIII and will be hopeful to solve the difficulties in eliminating muscular fatigue.
Shang
Xiliang
X
Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, PR China.
Chen
Shiyi
S
Ren
Huimin
H
Li
Yunxia
Y
Huang
He
H
D024403:Carbonic Anhydrase III / Q000008:administration & dosage* / Q000494:pharmacology*; D015444:Exercise; D006801:Humans; D018763:Muscle Fatigue / Q000187:drug effects*
D024403:Carbonic Anhydrase III