title: The primary cilium: a small yet mighty organelle.
abstract: Primary cilia are small, cylindrical membrane protrusions on most vertebrate cell types. Despite an unassuming appearance, this organelle has proven to be a veritable nexus of tightly regulated cell-signal reception between the epithelium and mesenchyme. In this issue, Lehman et al. describe the necessity of Ift88 and intraflagellar transport for signal reception of the sonic hedgehog pathway in the dermal papilla of developing hair follicles.
authors.affiliation: Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
authors.forename: Mindy C
authors.initials: MC
authors.lastname: DeRouen
authors.forename: Anthony E
authors.initials: AE
authors.lastname: Oro
mesh_terms: D000818:Animals; D002923:Cilia / Q000502:physiology*; D004847:Epithelial Cells / Q000502:physiology* / Q000648:ultrastructure*; D018859:Hair Follicle / Q000166:cytology* / Q000254:growth & development* / Q000502:physiology; D006801:Humans