Characterization of key intermediates in a complex organocatalytic cascade reaction using mass spectrometry.
Chemical scrabble: Mechanistic studies of complex organocatalytic cascade reactions are challenging owing to the presence of many species involved. Electrospray ionization mass spectrometry provides details about a one-pot quadruple organocatalytic cascade reaction, and allows detailed characterization of the reaction and its key intermediates.
Schrader
Wolfgang
W
Max-Planck-Institut für Kohlenforschung, Kaiser Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany. wschrader@mpi-muelheim.mpg.de
Handayani
Peni Purwa
PP
Zhou
Jian
J
List
Benjamin
B