title: Micropatterned surfaces with covalently grafted unsymmetrical polyoxometalate-hybrid clusters lead to selective cell adhesion.
abstract: Mn-Anderson based polyoxometalate clusters with different terminal groups have been patterned successfully onto self-assembled monolayer (SAM) using microcontact printing. Studies of the interactions between the designed SAMs and human fibroblast (hTERT-BJ1) cells have been reported, and it was observed that cells attach and spread efficiently for monolayer presenting a terminal aromatic pyrene platform with a polyoxometalate Mn-Anderson cluster as linker, demonstrating the crucial role played by the polyoxometalate metal oxide cluster as an intermediary in cell adhesion to the surface.
authors.affiliation: WestCHEM Department of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow, G12 8QQ UK.
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Song
authors.forename: Nicola
authors.initials: N
authors.lastname: McMillan
authors.forename: De-Liang
authors.initials: DL
authors.lastname: Long
authors.forename: Struan
authors.initials: S
authors.lastname: Kane
authors.forename: Jakob
authors.initials: J
authors.lastname: Malm
authors.forename: Mathis O
authors.initials: MO
authors.lastname: Riehle
authors.forename: Chullikkattil P
authors.initials: CP
authors.lastname: Pradeep
authors.forename: Nikolaj
authors.initials: N
authors.lastname: Gadegaard
authors.forename: Leroy
authors.initials: L
authors.lastname: Cronin
mesh_terms: D002448:Cell Adhesion; D002460:Cell Line; D006801:Humans; D008855:Microscopy, Electron, Scanning; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013499:Surface Properties; D017973:Tungsten Compounds / Q000737:chemistry*; D000099294:Polyoxometalates
chemical_list: D017973:Tungsten Compounds; C102296:polyoxometalate I; D000099294:Polyoxometalates