title: [The significance of intravenous immunoglobulin in treatment of immune-mediated polyneuropathies].
abstract: Long-term treatment of immune-mediated polyneuropathies remains difficult. For acute polyneuritis, or Guillain-Barré syndrome, the established standard therapy utilizes high doses of polyvalent intravenous immunoglobulins (IVIG). A recently published randomized placebo-controlled study of patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) showed IVIG to be clinically effective also for this disorder in both short and long term. This survey presents data of this so-called ICE study ("Intravenous immune globulin for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy"). It also discusses the value of IVIG in the treatment of immune-mediated polyneuropathies.
authors.affiliation: Klinik für Neurologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Stangel
authors.forename: H-P
authors.initials: HP
authors.lastname: Hartung
authors.forename: R
authors.initials: R
authors.lastname: Gold
authors.forename: B C
authors.initials: BC
authors.lastname: Kieseier
mesh_terms: D006801:Humans; D016867:Immunocompromised Host / Q000187:drug effects* / Q000276:immunology*; D007136:Immunoglobulins / Q000008:administration & dosage*; D007275:Injections, Intravenous; D011115:Polyneuropathies / Q000188:drug therapy* / Q000276:immunology*
chemical_list: D007136:Immunoglobulins