DichroCalc--circular and linear dichroism online.
BACKGROUND
Circular dichroism (CD) is widely used in studies of protein folding. The CD spectrum of a protein can be estimated from its structure alone, using the well-established matrix method. In the last decade, a related spectroscopy, linear dichroism (LD), has been increasingly applied to study the orientation of proteins in solution. However, matrix method calculations of LD spectra have not been presented before. DichroCalc makes both CD and LD calculations available in an easy-to-use fashion.


RESULTS
DichroCalc can be used without registration and calculates CD and LD spectra using a variety of matrix method parameters. PDB files can be uploaded as input or retrieved via their PDB code and a Perl-based parser is offered for easy handling of PDB files.


BACKGROUND
http://comp.chem.nottingham.ac.uk/dichrocalc and http://comp.chem.nottingham.ac.uk/parsepdb.
Bulheller
Benjamin M
BM
School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Hirst
Jonathan D
JD
D002942:Circular Dichroism / Q000379:methods*; D030562:Databases, Protein; D020407:Internet; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D012984:Software
D011506:Proteins