The potential of phage therapy in bacterial infections of the eye.
Antibiotic resistance has become a major health challenge which poses a significant threat, also in ophthalmology. For example, methicillin-resistant Staphylococcus aureus may cause dramatic complications, including bilateral blindness as a consequence of orbital cellulitis and panophthalmitis. This menace has provoked a greatly revived interest in phage therapy. In recent years, a number of papers have been published suggesting its efficacy in animal and human bacterial infections, but none of them addressed the phage potential in ophthalmology, which is the subject of this mini review.
Górski
Andrzej
A
L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland. agorski@ikp.pl
Targońska
Magdalena
M
Borysowski
Jan
J
Weber-Dabrowska
Beata
B
D000818:Animals; D001435:Bacteriophages; D001691:Biological Therapy / Q000639:trends*; D024881:Drug Resistance, Bacterial; D015818:Eye Infections, Bacterial / Q000628:therapy*; D006801:Humans