Adult issues in phenylketonuria.
Phenylketonuria (PKU) is a classical example of an inherited metabolic disease, in which mental retardation can be prevented successfully by using a diet. However, in adult PKU new problems occur, such as vitamin deficiencies, osteoporosis and the maternal PKU syndrome. The aim of this review article is to provide guidelines for the clinician to understand and manage PKU in adults.
Hoeks
M P A
MP
Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, the Netherlands.
den Heijer
M
M
Janssen
M C H
MC
D000367:Age Factors; D000596:Amino Acids / Q000627:therapeutic use; D019587:Dietary Supplements; D006801:Humans; D010024:Osteoporosis / Q000209:etiology; D010661:Phenylketonurias / Q000150:complications / Q000175:diagnosis* / Q000178:diet therapy / Q000628:therapy
D000596:Amino Acids