title: 1,5-Alpha-D-mannoseptanosides, ring-size isomers that are impervious to alpha-mannosidase-catalyzed hydrolysis.
abstract: 1,5-D-mannoseptanosyl di- and trisaccharide ring-size isomers of the corresponding mannopyranosyl oligosaccharides have been prepared. Remarkably, these compounds show no inhibition of the alpha-mannosidase-catalyzed hydrolysis of p-nitrophenyl-alpha-D-mannopyranoside.
authors.affiliation: Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Boone
authors.forename: Frank E
authors.initials: FE
authors.lastname: McDonald
authors.forename: Joseph
authors.initials: J
authors.lastname: Lichter
authors.forename: Stefan
authors.initials: S
authors.lastname: Lutz
authors.forename: Rui
authors.initials: R
authors.lastname: Cao
authors.forename: Kenneth I
authors.initials: KI
authors.lastname: Hardcastle
mesh_terms: D002384:Catalysis; D006868:Hydrolysis; D008362:Mannosides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D043323:alpha-Mannosidase / Q000378:metabolism*
chemical_list: D008362:Mannosides; D009844:Oligosaccharides; D043323:alpha-Mannosidase