[Application of simultaneous determination method of residual veterinary drugs to processed foods].
To ensure the safety of processed foods, we developed a method for simultaneous determination of residual veterinary drugs in some processed foods. Eighty-nine compounds were selected for the analysis based on reports of illegal use of the veterinary drugs and our research information. In our LC/MS/MS system, an Atlantis C(18) column, which could separate a wide range of compounds, was used with a gradient system of 0.1% formic acid-acetonitrile containing 0.1% formic acid as the mobile phase. Sharp and symmetrical peaks with sufficient signal intensity were obtained. In this system, the recovery rates of detected veterinary drugs in processed foods were mostly in the range of 60-120%. Therefore, it is considered that this method is suitable for screening of residual veterinary drugs in processed foods.
Fujita
Miho
M
Ezaki Glico Co., Ltd., Health Science Laboratory, Osaka, Japan.
Tamura
Wataru
W
Tozawa
Takahiro
T
Kometani
Takashi
T
D002853:Chromatography, Liquid; D004350:Drug Residues / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D053719:Tandem Mass Spectrometry; D019155:Veterinary Drugs / Q000032:analysis*
D019155:Veterinary Drugs