title: Steroidal saponins from Tribulus terrestris.
abstract: Five new steroidal saponins were isolated from the fruits of Tribulus terrestris. Their structures were fully established by spectroscopic and chemical analysis as (23S,25S)-5alpha-spirostane-24-one-3beta,23-diol-3-O-{alpha-l-rhamnopyranosyl-(1-->2)-O-[beta-d-glucopyranosyl-(1-->4)]-beta-d-galactopyranoside} (1), (24S,25S)-5alpha-spirostane-3beta,24-diol-3-O-{alpha-l-rhamnopyranosyl-(1-->2)-O-[beta-d-glucopyranosyl-(1-->4)]-beta-d-galactopyranoside} (2), 26-O-beta-d-glucopyranosyl-(25R)-5alpha-furostan-2alpha,3beta,22alpha,26-tetraol-3-O-{beta-d-glucopyranosyl-(1-->2)-O-beta-d-glucopyranosyl-(1-->4)-beta-d-galactopyranoside} (3), 26-O-beta-d-glucopyranosyl-(25R)-5alpha-furostan-20(22)-en-2alpha,3beta,26-triol-3-O-{beta-d-glucopyranosyl-(1-->2)-O-beta-d-glucopyranosyl-(1-->4)-beta-d-galactopyranoside} (4), and 26-O-beta-d-glucopyranosyl-(25S)-5alpha-furostan-12-one-22-methoxy-3beta,26-diol-3-O-{alpha-l-rhamnopyranosyl-(1-->2)-O-[beta-d-glucopyranosyl-(1-->4)]-beta-d-galactopyranoside} (5). The isolated compounds were evaluated for cytostatic activity against HL-60 cells.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, PR China.
authors.forename: Lan
authors.initials: L
authors.lastname: Su
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Sheng-Guang
authors.initials: SG
authors.lastname: Feng
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Zhi-Feng
authors.initials: ZF
authors.lastname: Li
authors.forename: Huan
authors.initials: H
authors.lastname: Chen
authors.forename: Ying-Xue
authors.initials: YX
authors.lastname: Liu
authors.forename: Yue-Hu
authors.initials: YH
authors.lastname: Pei
mesh_terms: D002236:Carbohydrate Conformation; D009682:Magnetic Resonance Spectroscopy; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification*; D012503:Saponins / Q000302:isolation & purification*; D013113:Spin Labels; D032444:Tribulus / Q000737:chemistry*
chemical_list: D010840:Phytosterols; D012503:Saponins; D013113:Spin Labels