title: NMR enantiodifferentiation of quaternary ammonium salts of Tröger base.
abstract: Hexacoordinated phosphorus BINPHAT anion 1 is an efficient NMR chiral solvating agent for quaternary ammonium cations (quats) derived from Tröger base leading to large separations of the proton signals of the enantiomers and even in polar solvent media such as CD(3)CN (Delta Delta delta up to 0.12 ppm). Quite surprisingly, this efficacy in the NMR split efficiency is not translated into a supramolecular stereocontrol (Pfeiffer effect) of the cation configuration by the anion.
authors.affiliation: Department of Organic Chemistry, University of Geneva, CH-1211 Geneva 4, Switzerland.
authors.forename: Christophe
authors.initials: C
authors.lastname: Michon
authors.forename: Maria-Héléna
authors.initials: MH
authors.lastname: Gonçalves-Farbos
authors.forename: Jérôme
authors.initials: J
authors.lastname: Lacour