A fatal case of cerebral oedema with hyponatraemia and massive polyuria after renal transplantation.
We report the case of a child who died from severe cerebral oedema in the context of hyponatraemia and extreme polyuria immediately after renal transplantation. The patient was treated according to a standard post-transplantation protocol, receiving 0.45% saline solution for urine output replacement. The case highlights the dangers of massive fluid therapy in the context of polyuria and, therefore, the need for intensive monitoring.
Cansick
Janette
J
Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK.
Rees
Lesley
L
Koffman
Geoff
G
Van't Hoff
William
W
Bockenhauer
Detlef
D
D001929:Brain Edema / Q000601:surgery*; D002648:Child; D017809:Fatal Outcome; D005440:Fluid Therapy; D006801:Humans; D007010:Hyponatremia / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D011141:Polyuria / Q000188:drug therapy / Q000601:surgery*