title: Effects of different irrigation regimens on the sealing properties of repaired furcal perforations.
abstract: OBJECTIVE
  The pulp chamber is inevitably exposed to irrigants during endodontic therapy. This study aimed to investigate whether different irrigation regimens would alter the sealing ability of repaired furcal perforations.
  
  
  METHODS
  Pulp chambers of 90 extracted human molars were accessed, after which standardized diamond bur-cut perforations were created in the center of the pulp chamber floor. The canal orifices and the apical end of roots were sealed with acid-etch composite resin. Eighty teeth were randomly divided into 2 groups (n = 40/group) according to the material used for repairing the perforation defects: (1) Mineral trioxide aggregate (MTA), (2) Super-EBA. The remaining teeth (n = 10) served as controls. The specimens were further subgrouped according to the irrigation regimens applied over the repair site (n = 10/group): (a) 5.25% NaOCl, (b) 5.25% NaOCl + EDTA, (c) 5.25% NaOCl + MTAD, and (d) No irrigation. Coronal leakage was measured by the fluid-filtration method at 1 day and 1 week.
  
  
  RESULTS
  Fluid conductance was not affected by the type of repair material (P = .964) or time (P = .726), but was affected significantly by the irrigation regimens in the following ranking: (P < .001): NaOCl < or = No Irrigation < NaOCl + MTAD < or = NaOCl + EDTA.
  
  
  CONCLUSIONS
  The sealing ability of furcal perforations repaired with MTA or Super-EBA were differentially affected by exposure to the tested irrigation regimens.
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey. uyanikmo@yahoo.com
authors.forename: M Ozgur
authors.initials: MO
authors.lastname: Uyanik
authors.forename: Emre
authors.initials: E
authors.lastname: Nagas
authors.forename: Cem
authors.initials: C
authors.lastname: Sahin
authors.forename: Fugen
authors.initials: F
authors.lastname: Dagli
authors.forename: Zafer C
authors.initials: ZC
authors.lastname: Cehreli
mesh_terms: D017607:Aluminum Compounds / Q000627:therapeutic use; D017610:Calcium Compounds / Q000627:therapeutic use; D019343:Citric Acid / Q000009:adverse effects; D003763:Dental Leakage / Q000209:etiology*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D004318:Doxycycline / Q000009:adverse effects; D004338:Drug Combinations; D004492:Edetic Acid / Q000009:adverse effects; D006801:Humans; D008422:Materials Testing; D008963:Molar; D010087:Oxides / Q000627:therapeutic use; D011136:Polysorbates / Q000009:adverse effects; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D012388:Root Canal Irrigants / Q000009:adverse effects*; D017640:Silicates / Q000627:therapeutic use; D012973:Sodium Hypochlorite / Q000009:adverse effects; D017001:Tooth Demineralization; D014092:Tooth Root / Q000293:injuries*; D014945:Wound Healing / Q000187:drug effects*; D014950:Wounds, Penetrating / Q000188:drug therapy
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; C475043:MTAD (intracanal irrigant); D010087:Oxides; D011136:Polysorbates; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D017640:Silicates; C086631:mineral trioxide aggregate; D019343:Citric Acid; C084074:Super EBA; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D004318:Doxycycline