title: A controlled clinical interventional trial comparing 2% chloroprocaine-bupivicaine versus 2% lidocaine-bupivicaine for retrobulbar anesthesia in scleral buckling surgery.
abstract: OBJECTIVE
  We undertook this prospective study to compare the relative effectiveness of a bupivicaine mixture with either lidocaine or chloroprocaine for retrobulbar anesthesia in scleral buckling surgery, since chloroprocaine, in some types of nonocular nerve block anesthesia, has been demonstrated to be a more effective nerve block anesthetic.
  
  
  METHODS
  This prospective, randomized, double-blind, controlled, clinical, unicentre, interventional trial compared mixtures of lidocaine-bupivacaine with chloroprocaine-bupivacaine in scleral buckling surgery performed by 1 surgeon during a 12-month period.
  
  
  METHODS
  A total of 136 patients who underwent scleral buckling surgery constituted the cases studied.
  
  
  METHODS
  A total of 31 variables comprising surgical, anesthetic, and patient-centered data were analyzed to determine which drug combination was more efficacious.
  
  
  RESULTS
  No statistically significant differences were found between chloroprocaine and lidocaine mixtures for retrobulbar anesthesia in scleral buckling surgery from the point of view of the surgeon, anesthetist, or patient.
  
  
  CONCLUSIONS
  We found no difference in effectiveness for bupivicaine mixed with either lidocaine or chloroprocaine for retrobulbar anesthesia in scleral buckling surgery. Surgeon, anesthetist, and patient-centered data showed no differences in any of the measures studied.
authors.affiliation: Department of Ophthalmology, University of Health Network, Toronto Western Hospital, Toronto, Ont.
authors.forename: Efrem D
authors.initials: ED
authors.lastname: Mandelcorn
authors.forename: Colin J L
authors.initials: CJ
authors.lastname: McCartney
authors.forename: Mark S
authors.initials: MS
authors.lastname: Mandelcorn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local / Q000379:methods*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009915:Orbit; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis; D017060:Patient Satisfaction; D011343:Procaine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011446:Prospective Studies; D012163:Retinal Detachment / Q000601:surgery; D012591:Scleral Buckling; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D011343:Procaine; C004616:chloroprocaine; D008012:Lidocaine; D002045:Bupivacaine