Symmetry controls the face geometry of DNA polyhedra.
Two complementary strategies have been developed to control the face geometry during the self-assembly of DNA polyhedra from branched DNA nanomotifs (tiles). In these approaches, any two interacting tiles are not equivalent in terms of either sequence or orientation; thus, each face must contain an even number of tiles. As a demonstration, DNA cubes, whose each face contains four tiles, have been assembled through these approaches.
Zhang
Chuan
C
Department of Chemistry, Markey Center for Structural Biology and Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA.
Ko
Seung Hyeon
SH
Su
Min
M
Leng
Yujun
Y
Ribbe
Alexander E
AE
Jiang
Wen
W
Mao
Chengde
C
D020285:Cryoelectron Microscopy; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure; D008958:Models, Molecular; D009690:Nucleic Acid Conformation
D004247:DNA