Development of a magnetic Single Cell Micro Array.
Experiments using single cells are valuable for revealing individual cell behaviour, which is of interest to many biomedical researchers. In such experiments, various types of devices capable of aligning cells into organized arrays are often used. In this paper, we present a novel Single Cell Micro Array device that makes use of magnetic forces. Prototypes of this device have been fabricated, and successfully tested using Jurkat cells that have been labelled with nano-magnetic particles. Experimental results show that the prototypes are effective on capturing and placing the labelled cells in an array.
Liu
W
W
Department of Mechanical Engineering, University of Victoria, BC, Canada. wwnliu@me.uvic.ca
Dechev
N
N
Lee
S-W
SW
Foulds
I G
IG
Parameswaran
A
A
Burke
R
R
Park
E J
EJ
D000465:Algorithms; D000497:Alloys; D001672:Biocompatible Materials / Q000737:chemistry; D002478:Cells, Cultured; D003198:Computer Simulation; D004867:Equipment Design; D006801:Humans; D018189:Immunomagnetic Separation; D019169:Jurkat Cells; D008280:Magnetics; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D008904:Miniaturization; D010316:Particle Size; D012984:Software; D013997:Time Factors
D000497:Alloys; D001672:Biocompatible Materials