A direct thrombin inhibitor, lepirudin, for thrombophilic patients with inoperable critical limb ischemia.
Salmela
Birgitta
B
Department of Coagulation Disorders, Division of Internal Medicine and HUSLAB Laboratory Services, Helsinki University Central Hospital, Helsinki, Finland.
Albäck
Anders
A
Räike
Petri
P
Lepäntalo
Mauri
M
Lassila
Riitta
R
D000328:Adult; D000671:Amputation, Surgical; D000925:Anticoagulants / Q000627:therapeutic use*; D005121:Extremities / Q000098:blood supply* / Q000601:surgery; D005260:Female; D006629:Hirudins; D006801:Humans; D007511:Ischemia / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D013917:Thrombin / Q000037:antagonists & inhibitors*; D019851:Thrombophilia / Q000188:drug therapy*
D000925:Anticoagulants; D006629:Hirudins; D011994:Recombinant Proteins; D013917:Thrombin; C083544:lepirudin