title: Fibrous dysplasia in a Hong Kong community: the clinical and radiological features and outcomes of treatment.
abstract: OBJECTIVE
  To evaluate the principal clinical and radiological features of a consecutive series of cases of fibrous dysplasia (FD) affecting a Hong Kong Chinese community and to determine their outcome by follow-up.
  
  
  METHODS
  All cases were accompanied by appropriate radiography and were histopathologically confirmed as fibro-osseous lesions.
  
  
  RESULTS
  The clinical and radiological presentations, differential diagnoses and outcomes of follow-up of 21 consecutive FD cases were reviewed. Females were slightly more frequently affected, but there was no gender predilection for either jaw. The mean age at first presentation was 25 years, which upon adjustment for prior awareness fell to 21 years. The main symptom was swelling (including enlargement of the jaw). The maxilla and mandible were affected in 9 and 13 cases, respectively; both jaws were affected in 1 case. One case was of McCune-Albright syndrome. The sole provisional diagnosis for all lesions was FD; most lesions affected all or almost half the affected jaw. 17 patients were followed-up for a mean of 9 years.
  
  
  CONCLUSIONS
  This very detailed consecutive series followed up over many years, in which a number of cases recurred or were reactivated in adulthood, firmly dispells the notion that FD is a simple hamartoma in all cases. This community was quite amenable to really long-term follow-up.
authors.affiliation: Division of Oral and Maxillofacial Radiology, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada. dmacdon@interchange.ubc.ca
authors.forename: D S
authors.initials: DS
authors.lastname: Macdonald-Jankowski
authors.forename: T K
authors.initials: TK
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002681:China / Q000208:ethnology; D003937:Diagnosis, Differential; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology; D005359:Fibrous Dysplasia, Polyostotic / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D006723:Hong Kong; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D008439:Maxillary Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies; D012737:Sex Factors; D016896:Treatment Outcome; D055815:Young Adult