title: Rapid progression of HIV infection in infancy.
abstract: Transmission of HIV from mother to child can occur in utero, during labor or after delivery via breast feeding. Data on the fate of babies born with HIV in India are scarce. We present details of 25 infants with perinatally acquired HIV infection (virologically confirmed) to highlight the observed high rate of morbidity and mortality within the first 18 months of life. Our findings of rapid disease progression among perinatally infected HIV positive children underline the importance of early diagnosis and treatment.
authors.affiliation: Tuberculosis Research Center, Chennai, India
authors.forename: N Poorana Ganga
authors.initials: NP
authors.lastname: Devi
authors.forename: R
authors.initials: R
authors.lastname: Shenbagavalli
authors.forename: K
authors.initials: K
authors.lastname: Ramesh
authors.forename: S Nataraja
authors.initials: SN
authors.lastname: Rathinam
authors.forename: Soumya
authors.initials: S
authors.lastname: Swaminathan
mesh_terms: D018791:CD4 Lymphocyte Count; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000276:immunology / Q000401:mortality* / Q000628:therapy / Q000635:transmission; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D011446:Prospective Studies