Trifluoroacetic acid-mediated facile transformation of 2-C-hydroxymethyl-D-glycals to chiral pyrano[2,3-b]benzopyrans.
Treatment of 2-C-hydroxymethyl-D-glycals with phenols in trifluoroacetic acid at ambient temperature leads to an extremely facile transformation affording chiral pyrano[2,3-b]benzopyrans in high yields.
Santhi
Meenakshisundaram
M
Shasun Research Centre, Chennai, India.
Balasubramanian
Kalpattu K
KK
Bhagavathy
Shanmugasundaram
S
D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism; D013696:Temperature; D014269:Trifluoroacetic Acid / Q000737:chemistry*
D001578:Benzopyrans; D014269:Trifluoroacetic Acid