Discordance between Staphylococcus aureus nasal colonization and skin infections in children.
We examined nasal carriage of Staphylococcus aureus in otherwise healthy children presenting with skin and soft tissue infections. We found high rates of nasal colonization with S. aureus, but significant discordance between nasal and wound isolates. Recurrent skin and soft tissue infections were common but unrelated to baseline methicillin-resistant S. aureus nasal colonization status.
Chen
Aaron E
AE
Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA. achen33@jhmi.edu
Cantey
Joseph B
JB
Carroll
Karen C
KC
Ross
Tracy
T
Speser
Sharon
S
Siberry
George K
GK
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D007223:Infant; D008712:Methicillin / Q000494:pharmacology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D009296:Nasal Cavity / Q000382:microbiology*; D018461:Soft Tissue Infections / Q000453:epidemiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013207:Staphylococcal Skin Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D014946:Wound Infection / Q000453:epidemiology / Q000382:microbiology
D000900:Anti-Bacterial Agents; D008712:Methicillin