[Clinical efficacy of nonsurgical treatment of Crohn's disease-related intraabdominal abscess].
OBJECTIVE
This study was conducted to compare the clinical efficacy between surgical and nonsurgical treatments for patients with Crohn's disease-related intraabdominal abscess.


METHODS
A retrospective review of medical records was performed for patients admitted to a single institution due to Crohn's disease-related intraabdominal abscess from February, 1996 to February, 2008. Clinical outcomes were compared between surgical and nonsurgical groups in terms of treatment responses and recurrences.


RESULTS
A total of 47 episodes of intraabdominal abscesses in 43 patients (12.7%) were identified from 339 patients with Crohn's disease. Of these, initially, 18 cases (38.3%) underwent surgical treatment and 29 (61.7%) were treated medically (antibiotic treatments with or without percutaneous drainage). The overall treatment response rates of surgical and nonsurgical group were 100% versus 89.7% (p=0.11) and recurrence rates were 27.8% versus 30.8% (p=1.00). Three patients in nonsurgical group (10.3%) showed no response to therapy and ultimately received surgical drainages. The median length of hospitalization in nonsurgical group was shorter than in surgical group (12 and 29.5 days, respectively. p=0.02).


CONCLUSIONS
Nonsurgical treatment might be as effective as surgical treatment for the treatment of Crohn's disease-related intraabdominal abscess, especially considering shorter hospital stay.
Kim
Duk Hwan
DH
Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
Cheon
Jae Hee
JH
Moon
Chang Mo
CM
Park
Jae Jun
JJ
Han
Song Yi
SY
Kim
Eun Soo
ES
Chung
Moon Jae
MJ
Lee
Jin Ha
JH
Jung
Min Kyu
MK
Lee
Soo Hyun
SH
Son
Jung Woo
JW
Kim
Tae Il
TI
Kim
Won Ho
WH
D018784:Abdominal Abscess / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D003424:Crohn Disease / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D004322:Drainage; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012008:Recurrence; D012189:Retrospective Studies; D012720:Severity of Illness Index