title: [Does hormonal contraception increase the risk for tumors?].
abstract: A non-contraceptive benefit of oral hormonal contraceptives (OC) is a diminished risk for certain benign as well as malignant tumours, such as benign breast tumours, uterine fibroids and ovarian cysts. Endometriosis itself is not positively influenced by OC, but dysmenorrhea is decreased. Modern low-dose OC do not increase the risk of liver cell adenomata or carcinomata. OC do not influence melanoma. Modern data do not suggest an increased risk for breast carcinoma in OC users. Long-term use of OC leads to a decreased risk of endometrial and colorectal carcinomata. Cervical carcinoma is not influenced directly by OC, but probably indirectly through a change in sexual behaviour. There is no increase of vulvar or vaginal carcinoma, even after long-term use of OC.
authors.affiliation: Poliklinik für gynäkologische Endokrinologie und Reproduktionsmedizin, Universitätsklinikum Hamburg-Eppendorf. wilhelm.braendle@googlemail.de
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Braendle
authors.forename: Herbert
authors.initials: H
authors.lastname: Kuhl
authors.forename: Alfred
authors.initials: A
authors.lastname: Mueck
authors.forename: Martin
authors.initials: M
authors.lastname: Birkhäuser
authors.forename: Christian
authors.initials: C
authors.lastname: Thaler
authors.forename: Ludwig
authors.initials: L
authors.lastname: Kiesel
authors.forename: Joseph
authors.initials: J
authors.lastname: Neulen
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005833:Genital Neoplasms, Female / Q000139:chemically induced / Q000235:genetics; D006801:Humans; D008134:Long-Term Care; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced* / Q000235:genetics; D012307:Risk Factors; D055815:Young Adult
chemical_list: D003278:Contraceptives, Oral, Hormonal