An infant with congenital nemaline myopathy and hypertrophic cardiomyopathy.
We describe an infant with nemaline myopathy accompanied by hypertrophic cardiomyopathy. The patient required long-term, intermittent positive-pressure ventilation after birth owing to muscle weakness, and cardiac failure developed during infancy. We diagnosed hypertrophic cardiomyopathy with outflow tract obstruction, and treated the heart failure with beta-adrenergic and angiotensin II receptor blockers. We discuss the prognosis of nemaline myopathy combined with hypertrophic cardiomyopathy.
Nakajima
Mizue
M
Department of Pediatrics, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, Japan. s4019@nms.ac.jp
Shima
Yoshio
Y
Kumasaka
Sakae
S
Kuwabara
Kentaro
K
Migita
Makoto
M
Fukunaga
Yoshitaka
Y
D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D017696:Myopathies, Nemaline / Q000150:complications*