title: Clinical observations and seven-and-one-half-year follow-up of patients using an integrative holistic approach for treating chronic sinusitis.
abstract: BACKGROUND
  Despite the widespread popularity of alternative medical approaches to respiratory and allergic disorders, there is a lack of scientific substantiation of their benefits.
  
  
  OBJECTIVE
  Assessment of the therapeutic benefit of an integrative holistic approach to the treatment of chronic sinusitis.
  
  
  METHODS
  Patients began a 5-month program consisting of 5 evening sessions of 2 hours each in October of 1999.
  
  
  METHODS
  The program was held in the offices of one of the authors (WSS).
  
  
  METHODS
  Ten patients of an allergist-immunologist specialist (WSS), symptomatic despite aggressive conventional treatment for their chronic sinusitis, were recruited to participate in an integrative holistic medical education and treatment program consisting of 5 sessions and evaluated at a 1-year follow-up. Sessions consisted of education in lifestyle and indoor-air modification, nasal hygiene, and treatment with fluconazole. Eight of 9 subjects were located and provided feedback 7 years and 6 months later, in June 2007.
  
  
  METHODS
  Health-related quality of life (QOL) was assessed using the short-form QOL survey (SF-12) and rhinitis QOL by the Rhinitis Quality of Life Questionnaire (RQLQ).
  
  
  RESULTS
  No significant differences emerged in the SF-12 or mini-RQLQ scores comparing visit 2 with visit 1. Statistically significant improvement for physical and mental subscales of the SF-12 emerged comparing the results of visit 4 with visit 2 after the addition offluconazole treatment to the regimen, persisting through an additional year of follow-up. Feedback at 7.5 years confirmed marked long-term improvement in chronic sinusitis symptoms compared to their pre-study condition.
authors.affiliation: Department of Otolaryngology, University of Colorado Health Sciences Center, Denver, Colorado, USA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Ivker
authors.forename: William S
authors.initials: WS
authors.lastname: Silvers
authors.forename: Robert A
authors.initials: RA
authors.lastname: Anderson
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006266:Health Education / Q000379:methods*; D006694:Holistic Health; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012221:Rhinitis, Allergic, Perennial / Q000628:therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000628:therapy*; D016896:Treatment Outcome