[Immunomodulation effects volatile secretion of animals at postradiation immunodeficiency conditions].
Was shown, that given off with urine the volatile chemosignals of intact and irradiated (4 Gy) mice and rats restored the ability to humoral immune response and other parameters immunity lowered by ionizing radiation in the dose 1 Gy. The chemosignals off intact individuals have shown higher immunerestoring activity in comparison with the irradiated ones. As opposed to post-radiation signals they activated in the major degree at irradiational mice phagocytic activity peritoneal macrophages and also the number in the blood at rates not only erythrocytes but lymphocytes and granulocytes. It is supposed, that mammals possess the distant immunomodulating chemosignal system, direct on immunoreactivity of individuals with immunodeficiency of state.
Surinov
B P
BP
Isaeva
V G
VG
D000818:Animals; D049109:Cell Proliferation; D007153:Immunologic Deficiency Syndromes / Q000276:immunology* / Q000652:urine; D007155:Immunologic Factors / Q000276:immunology* / Q000652:urine*; D018655:Lymphocyte Count; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010950:Plasma Cells / Q000276:immunology; D011833:Radiation Injuries, Experimental / Q000276:immunology* / Q000652:urine; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology; D014835:Volatilization
D007155:Immunologic Factors