title: Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense.
abstract: Novel sesquiterpene, named crossostephin (1), and coumarin, named biscopoletin (2), together with four known compounds, artesin, tanacetin, scopoletin, and scopolin, were isolated from the 70% ethanolic extract of the whole herbs of Crossostephium chinense (L.) Makino. Their structures were determined by spectroscopic methods, including IR, UV, EIMS, HRFTICRMS, 1D and 2D NMR spectral analyses. Both scopoletin and scopolin were isolated from the title plant for the first time.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.forename: Lei
authors.initials: L
authors.lastname: Zou
authors.forename: Xiu-Wei
authors.initials: XW
authors.lastname: Yang
authors.forename: De-Xian
authors.initials: DX
authors.lastname: Fu
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D003374:Coumarins; D005960:Glucosides; D012717:Sesquiterpenes; C539515:biscopoletin; C539514:crossostephin; C417572:scopolin