Role of glycemic elements of Cynodon dactylon and Musa paradisiaca in diabetes management.
The study defined the scientific evaluation of glycemic elements of extracts of Cynodon dactylon and Musa paradisiaca. A dose of 500 mg/kg body weight (bw) of C. dactylon produced maximum falls of 23.2% and 22.8% in blood glucose levels of normoglycemic rats during studies of fasting blood glucose and glucose tolerance, respectively, whereas the same dose of M. paradisiaca produced a rise of 34.9% and 18.4%. In diabetic rats during glucose tolerance tests, a fall of 27.8% and a rise of 17.5% were observed with the same dose of C. dactylon and M. paradisiaca, respectively. Laser-induced breakdown spectroscopy used for detection of glycemic elements present in both the extracts indicated that C. dactylon was rich in magnesium (Mg), whereas M. paradisiaca was rich in potassium (K) and sodium (Na), comparatively, suggesting thereby the defined roles of these elements in diabetes management.
Rai
Prashant Kumar
PK
Drug Discovery & Development Division, Medicinal Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, India.
Jaiswal
Dolly
D
Rai
Nilesh K
NK
Pandhija
Shiwani
S
Rai
A K
AK
Watal
Geeta
G
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D031744:Cynodon / Q000737:chemistry; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000627:therapeutic use; D053844:Lasers, Solid-State; D008297:Male; D028521:Musa / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013057:Spectrum Analysis / Q000379:methods
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts