[A case-crossover study on air pollutants and the mortality of stroke].
OBJECTIVE
To investigate the short-term effect of particulate matter in air on the mortality of stroke.


METHODS
Using time-stratified case-crossover study design, an association was examined between stroke mortality and particulate matter with aerodynamic diameter of < 10 microm (PM10) of 2002 - 2004 in Hangzhou city. Meanwhile, the acute health effect of other gaseous pollutants (sulfur dioxide, SO2 and nitrogen dioxide, NO2) was also analyzed.


RESULTS
A total of 9906 deaths of stroke were included. The crude stroke mortality was 83.54 per 100 000. After being adjusted for meteorological factors, when an increase of 10 microg/m3 in PM10, SO2 and NO2 in three days was noticed, it appeared that the increases of mortality of stroke were 0.56% (95% CI: 0.14%-0.99%), 1.62% (95% CI: 0.26% - 3.01%) and 2.07% (95% CI: 0.54% - 3.62%) respectively. There was no distinct association in multi-pollutant models. In sensitivity analysis, the associations were found in all single-pollutant models but not statistically significant in multi-pollutant models after replacing the missing values.


CONCLUSIONS
It is suggested that the short-term elevation in PM10 as well as SO2 and NO2 daily concentrations were related to the increase of stroke mortality in Hangzhou city.
Ren
Yan-Jun
YJ
Hangzhou Center for Disease Control and Prevention, Hangzhou 310006, China.
Li
Xiu-Yang
XY
Chen
Kun
K
Liu
Qing-Min
QM
Xiang
Hai-Qing
HQ
Jin
Da-Feng
DF
Chen
Ren-Hua
RH
D000368:Aged; D000369:Aged, 80 and over; D000393:Air Pollutants / Q000032:analysis*; D002423:Cause of Death; D002681:China / Q000453:epidemiology; D018592:Cross-Over Studies; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D008962:Models, Theoretical; D009585:Nitrogen Dioxide / Q000032:analysis; D052638:Particulate Matter / Q000032:analysis*; D020521:Stroke / Q000453:epidemiology / Q000401:mortality*; D013458:Sulfur Dioxide / Q000032:analysis; D013997:Time Factors
D000393:Air Pollutants; D052638:Particulate Matter; D013458:Sulfur Dioxide; D009585:Nitrogen Dioxide