title: Chronic granulomatous disease in an adolescent with recurrent impetigo and cholecystectomy.
abstract: Chronic granulomatous disease is a rare primary immunodeficiency disorder resulting from a defect in the microbicidal activity of phagocytes. Patients are susceptible to certain bacterial and fungal infections, as well as other inflammatory complications. We report the case of a 12-year-old girl with recurrent impetigo whose history of cholecystitis triggered an evaluation that revealed chronic granulomatous disease.
authors.affiliation: Division of Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. ellen.scholnicoff@chp.edu
authors.forename: Ellen T
authors.initials: ET
authors.lastname: Scholnicoff
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: MacGinnitie
authors.forename: Philana Ling
authors.initials: PL
authors.lastname: Lin
authors.forename: Toni
authors.initials: T
authors.lastname: Darville
mesh_terms: D000208:Acute Disease; D002648:Child; D002763:Cholecystectomy; D002764:Cholecystitis / Q000150:complications* / Q000601:surgery; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007169:Impetigo / Q000150:complications* / Q000382:microbiology; D012008:Recurrence; D013203:Staphylococcal Infections / Q000150:complications / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification