Metastatic uterine leiomyosarcoma presenting as a breast lump.
BACKGROUND
It is uncommon to encounter a breast metastasis from an extramammary malignancy and even rarer from a uterine leiomyosarcoma.


OBJECTIVE
We describe the third case report in the medical literature of a breast metastasis from a uterine leiomyosarcoma.


METHODS
We report the management of a 56-year-old patient who presented with a breast lump 3 years after hysterectomy for a fibroid uterus. We conducted a literature review of breast leiomyosarcomas.


RESULTS
The excision of the breast mass revealed a low-grade leiomyosarcoma. Radiographic examinations demonstrated metastases to the lung, liver, pelvis and bone. Retrospective pathology review of her uterus identified a small focus of leiomyosarcoma. She received chemotherapy and palliative radiotherapy but passed away within few months.


CONCLUSIONS
Metastasis to the breast from a non-breast primary is generally a sign of disseminated disease and; thus, a poor prognostic indicator.
Sibartie
S
S
Department of Surgery, South Infirmary Victoria University Hospital, Cork, Ireland. shomiksibartie@gmail.com
Larkin
J O
JO
Lee
G
G
Fitzgibbon
J
J
O'Reilly
S
S
Richardson
D
D
D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000556:secondary; D014594:Uterine Neoplasms / Q000473:pathology*