[Phenolic acids from Arnebia euchroma mifepristone in anti-early pregnancy of SD rattus norvegicus].
OBJECTIVE
Observing the effect of phenolic acids from Arnebia euchroma assist mifepristone in anti-early pregnancy of SD rattus norvegicus.


METHODS
Feed the SD rattus norvegicus with phenolic acids from A. euchroma during the 7 th to 9 th day, and then we observe the restaining rate of pregnancy. At the same time, we determine the progesterone level in blood serum in the ways of radioimmunoassay.


RESULTS
720 g x kg(-1) enolic aids from A. euchroma can markedly increase the restaining rate of pregnancy (P < 0.05) than that only mifepristone dose (8.0 g x kg(-1)). In addition, the number of everage still bith increase, however, to the pogesterone level in blood serum. It has little effect.


CONCLUSIONS
The effect of phenolic acids from A. euchroma assist mifepristone in anti-early pregnancy of SD rattus norvegicus is clear, and it dosen't work in the ways of decreasing the pogesterone level.
Wang
Li-Jun
LJ
South-central University for Nationalities, Wuhan 430074, China.
Zhang
Xin-Yi
XY
Liao
Mao-Chuan
MC
D000019:Abortifacient Agents / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D028082:Boraginaceae / Q000737:chemistry*; D005260:Female; D062385:Hydroxybenzoates / Q000737:chemistry / Q000494:pharmacology*; D008297:Male; D015735:Mifepristone / Q000494:pharmacology*; D011247:Pregnancy / Q000187:drug effects*; D011374:Progesterone / Q000097:blood; D011863:Radioimmunoassay; D051381:Rats; D017207:Rats, Sprague-Dawley
D000019:Abortifacient Agents; D062385:Hydroxybenzoates; D015735:Mifepristone; D011374:Progesterone; C017616:phenolic acid