title: Perinatal outcome of monoamniotic twin pregnancies.
abstract: OBJECTIVE
  To study perinatal mortality and neonatal morbidity in a large cohort of monoamniotic twin pregnancies with special emphasis to the gestational age-specific mortality.
  
  
  METHODS
  The study included monoamniotic twin pregnancies delivered in 10 perinatal centers in the Netherlands between January 2000 and December 2007.
  
  
  RESULTS
  A total of 98 monoamniotic pregnancies were included. The perinatal mortality rate (20 weeks of gestation through 28 days of life) was 19%; after exclusion of fetuses with lethal anomalies, the rate was 17%. After 32 weeks of gestation, only two pregnancies were complicated by perinatal mortality (4%). The incidence of twin-twin transfusion syndrome was 6%. The incidence of congenital heart anomalies and cerebral injury was 4% and 5%, respectively.
  
  
  CONCLUSIONS
  The current incidence of perinatal mortality in monoamniotic twins is considerably lower than in previous decades, but it is still high and occurs throughout pregnancy.
  
  
  METHODS
  III.
authors.affiliation: Department of Obstetrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht the Netherlands. k.e.a.hack@umcutrecht.nl
authors.forename: Karien E
authors.initials: KE
authors.lastname: Hack
authors.forename: Jan B
authors.initials: JB
authors.lastname: Derks
authors.forename: Arty H
authors.initials: AH
authors.lastname: Schaap
authors.forename: Enrico
authors.initials: E
authors.lastname: Lopriore
authors.forename: Sjoerd G
authors.initials: SG
authors.lastname: Elias
authors.forename: Birgit
authors.initials: B
authors.lastname: Arabin
authors.forename: Alex J
authors.initials: AJ
authors.lastname: Eggink
authors.forename: Krystyna M
authors.initials: KM
authors.lastname: Sollie
authors.forename: Ben Willem J
authors.initials: BW
authors.lastname: Mol
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Duvekot
authors.forename: Christine
authors.initials: C
authors.lastname: Willekes
authors.forename: Attie T
authors.initials: AT
authors.lastname: Go
authors.forename: Corine
authors.initials: C
authors.lastname: Koopman-Esseboom
authors.forename: Frank P
authors.initials: FP
authors.lastname: Vandenbussche
authors.forename: Gerard H
authors.initials: GH
authors.lastname: Visser
mesh_terms: D000650:Amnion / Q000473:pathology; D015331:Cohort Studies; D004200:Diseases in Twins / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D005330:Fetofetal Transfusion / Q000401:mortality; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D014430:Twins, Monozygotic