title: [Levels of transition on maternal transferred measles antibody in infants in 3 cities in China].
abstract: OBJECTIVE
  To understand the epidemiological characteristics of age distribution of measles and related policies on measles vaccines (live; MV) in infants through analyzing the antibody levels of comparison in maternal-infant pairs. Transition of immunity in infants was also studied to provide theoretic basis for measles immunization strategy and to reduce the incidence of month-old infants.
  
  
  METHODS
  In cities of Ningbo, Harbin, and Jinan from Zhejiang, Heilongjiang and Shandong provinces, data was collected from 2004 to 2007 and analyzed regarding the epidemic situation of measles. Studies on maternal-transferred measles antibody were carried our sero-epidemiologically.
  
  
  RESULTS
  Most of the measles cases were found among babies younger than 12 months, and the incidence of < 1 year olds had been increasing. The distribution was dominated by 5 - 8 month olds in infant measles cases. The positive rate and GRMT of measles antibody in newborns were 89.3 percent and 738.93. The positive rate of the measles antibody and GMRT of the 6-month infant were 6.9% and 6.89, while 6.7% and 3.69 in 8-month infant. There was a declining trend of the positive rate of the measles antibody during the newborns to 8-month infant. The positive rate and GRMT of measles antibody in mothers were 84.3 percent and 516.94. Mother's measles antibodies mainly to be at low and moderate level, which accounted for 50.4 percent and 30.3 percent respectively, the correlation coefficient between mother and infant was 0.840.
  
  
  CONCLUSIONS
  Maternal-transferred measles antibody decreased as the growth of infants. The positive rates of measles antibody were quite low in 6-month and 8-month olds which were the age range that needs most attention.
authors.affiliation: Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China.
authors.forename: Guo-zhang
authors.initials: GZ
authors.lastname: Xu
authors.forename: Rui
authors.initials: R
authors.lastname: Ma
authors.forename: Hong-jie
authors.initials: HJ
authors.lastname: Xu
authors.forename: Yan-hui
authors.initials: YH
authors.lastname: Ma
authors.forename: Hong-jun
authors.initials: HJ
authors.lastname: Dong
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Feng-xia
authors.initials: FX
authors.lastname: Hu
authors.forename: Hong-xia
authors.initials: HX
authors.lastname: Ni
authors.forename: Guo-lin
authors.initials: GL
authors.lastname: Bian
authors.forename: Ying
authors.initials: Y
authors.lastname: Liang
authors.forename: Lan-zheng
authors.initials: LZ
authors.lastname: Liu
authors.forename: Shao-ying
authors.initials: SY
authors.lastname: Zhou
authors.forename: Qing-jie
authors.initials: QJ
authors.lastname: Huai
authors.forename: Xiu-yun
authors.initials: XY
authors.lastname: Han
mesh_terms: D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007117:Immunization, Secondary; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D008457:Measles / Q000453:epidemiology* / Q000276:immunology* / Q000517:prevention & control; D011247:Pregnancy; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G