title: Automation in anesthesia: computer controlled propofol infusion and data acquisition.
abstract: This work presents the improvement of a software for a clinical setup, the Anesthesia Synchronization Software (ASYS). The first version presented the data acquisition from cerebral monitors and a partial control with Target Controlled Infusion (TCI) system. Based on pharmacokinetic models, the effect-site and plasma concentrations can be related with the drug dose infused and vice versa. This later version comes with the implementation of the hemodynamic monitor always present in operating rooms and with the full TCI system developed to determine the infusion rates of the drug which are given as commands to the infusion pumps.
authors.affiliation: Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal. nadja.bressan@fe.up.pt
authors.forename: Nadja
authors.initials: N
authors.lastname: Bressan
authors.forename: Ana
authors.initials: A
authors.lastname: Castro
authors.forename: Carlos
authors.initials: C
authors.lastname: Braga
authors.forename: Jose
authors.initials: J
authors.lastname: Lages
authors.forename: Nuno R
authors.initials: NR
authors.lastname: Silva
authors.forename: Paulo
authors.initials: P
authors.lastname: Portela
authors.forename: Pedro
authors.initials: P
authors.lastname: Miranda
authors.forename: Sergio
authors.initials: S
authors.lastname: Oliveira
authors.forename: Joaquim
authors.initials: J
authors.lastname: Mendes
authors.forename: Pedro
authors.initials: P
authors.lastname: Amorim
authors.forename: Catarina S
authors.initials: CS
authors.lastname: Nunes
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D006801:Humans; D007260:Infusion Pumps; D007262:Infusions, Intravenous; D008954:Models, Biological; D015742:Propofol / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D015742:Propofol