title: A nonenzymatic biosensor based on copper nanoparticles modified electrode for detection of acetylcholine.
abstract: The electrocatalytic oxidation of acetylcholine (Ach) on copper microparticles modified carbon paste electrode (m-CPE) and copper nanoparticles-modified carbon paste electrode (n-CPE) was investigated. In the voltammogram recorded using m-CPE, a single anodic peak related to the oxidation of ACh was observed. Using n-CPE, however, two overlapped anodic peaks were observed. The amino acids oxidized on n-CPE at higher rates at lower potentials compared to m-CPE. A nonenzymatic amperometric biosensor was constructed and a simple analysis procedure was developed for the determination of ACh.
authors.affiliation: Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran. jabbari@kntu.ac.ir
authors.forename: Ali
authors.initials: A
authors.lastname: Jabbari
authors.forename: Hossein
authors.initials: H
authors.lastname: Heli
authors.forename: Maryam
authors.initials: M
authors.lastname: Hajjizadeh
authors.forename: Ali A
authors.initials: AA
authors.lastname: Moosavi-Movahedi
mesh_terms: D000109:Acetylcholine / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D002244:Carbon / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D004566:Electrodes; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D002244:Carbon; D003300:Copper; D000109:Acetylcholine