Researchers worry about myopathy risk for patients taking high-dose simvastatin.
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D020022:Genetic Predisposition to Disease; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D027381:Liver-Specific Organic Anion Transporter 1; D009135:Muscular Diseases / Q000139:chemically induced* / Q000235:genetics*; D027361:Organic Anion Transporters / Q000235:genetics*; D012206:Rhabdomyolysis / Q000139:chemically induced / Q000235:genetics; D012306:Risk; D019821:Simvastatin / Q000009:adverse effects*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D027381:Liver-Specific Organic Anion Transporter 1; D027361:Organic Anion Transporters; C503999:SLCO1B1 protein, human; D019821:Simvastatin