[Tuberculosis-associated immune reconstitution inflammatory syndrome].
The prognosis of HIV-infected patients has dramatically improved since the advent of HAART. The immune recovery associated with HAART may result in immuno-pathological reactions and clinical deterioration when HAART is initiated in patients with tuberculosis (TB). This phenomenon is defined as immune reconstitution inflammatory syndrome (IRIS). In this review, we summarise the epidemiology, clinical presentations and management of TB-associated IRIS.
Leone
S
S
U.O.C. Malattie Infettive, AORN San Giuseppe Moscati, Avellino, Italy.
Nicastri
E
E
Giglio
S
S
Corpolongo
A
A
Narciso
P
P
Acone
N
N
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D015994:Incidence; D015995:Prevalence; D012307:Risk Factors; D012384:Rome / Q000453:epidemiology; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*
D000995:Antitubercular Agents; D005938:Glucocorticoids