title: [Three case reports of metastatic germ cell tumors in the lumbar vertebra during first-line chemotherapy].
abstract: We report three patients with germ cell tumors whose diagnosis was confirmed in the progress of the first-line chemotherapy regimen as metastatic cancer in the lumbar vertebra. Two of the 3 cases were mixed-type nonseminoma, and the other case was an extragonadal tumor. After the first-line chemotherapy regimen, the patients underwent salvage chemotherapy using Paclitaxel either with or without irradiation. We confirmed the efficacy that the bone metastasis had completely been resolved and the lymph node metastasis was significantly reduced after the completion of all treatments.
authors.affiliation: The Department of Urology, Kitasato University School of Medicine.
authors.forename: Masato
authors.initials: M
authors.lastname: Dobashi
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Son
authors.forename: Masaomi
authors.initials: M
authors.lastname: Ikeda
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Fujita
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Takefumi
authors.initials: T
authors.lastname: Satoh
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Iwamura
authors.forename: Shiro
authors.initials: S
authors.lastname: Baba
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy* / Q000473:pathology*; D016879:Salvage Therapy; D013125:Spinal Neoplasms / Q000556:secondary*; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology*