[Molecular determinants in regulating Pseudomonas aeruginosa type III secretion system--a review].
Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen. Successful injection of virulence factors into host cells, evasion of phagocytosis and promotion of pathogenesis depend primarily on the function of type III secretion system (T3SS). A complex set of signaling pathways have been shown to modulate T3SS expression. In this review, a brief introduction is given on the composition, function, and molecular determinants that regulate P. aeruginosa T3SS gene expression.
Luo
Qin
Q
Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Science, Central China Normal University, Wuhan 430079, China. qinluo@mail.ccnu.edu.cn
Jin
Shouguang
S
D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D021381:Protein Transport; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D037521:Virulence Factors / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D037521:Virulence Factors