title: [Polioxidonium in comprehensive therapy of recurrent herpetic stomatitis in children with allergic diseases].
abstract: In the study with participation of 96 children of 1-7 years age with recurrent herpetic stomatitis and allergic diseases therapeutic efficacy of Polioxidonium was investigated. Polioxidonium was used in combination with traditional methods and with He-Ne-laser irradiation. Local oral cavity immunity, indexes of cellular immunity (in the reaction of lymphocytes blast-transformation with phytohemagglutinin), indexes of humoral immunity (IgG and IgE) were studied, complement C(3)-component was determined. Polioxidonium in combination with traditional methods and with laser therapy for recurrent herpetic stomatitis treatment in children with allergic diseases influenced favourably upon clinical course of allergic diseases, let achieve stable remission, increased efficacy of their treatment, promoted immunological status and shorten the terms of medical rehabilitation.
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Kuznetsova
authors.forename: L N
authors.initials: LN
authors.lastname: Maksimovskaia
authors.forename: I I
authors.initials: II
authors.lastname: Balabolkin
authors.forename: A P
authors.initials: AP
authors.lastname: Gorshenina
authors.forename: G V
authors.initials: GV
authors.lastname: Semenov
mesh_terms: D007611:Aprotinin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D007223:Infant; D007273:Injections, Intramuscular; D053685:Laser Therapy / Q000379:methods*; D010879:Piperazines / Q000627:therapeutic use*; D011108:Polymers / Q000627:therapeutic use*; D012008:Recurrence; D013283:Stomatitis, Herpetic / Q000188:drug therapy* / Q000453:epidemiology* / Q000628:therapy; D014361:Trypsin Inhibitors / Q000627:therapeutic use*
chemical_list: D007155:Immunologic Factors; D010879:Piperazines; D011108:Polymers; D014361:Trypsin Inhibitors; D007611:Aprotinin; C540909:azoximer bromide