title: [Study on the relationship between obesity and clustering of major risk factors on cardiovascular diseases in the elderly].
abstract: OBJECTIVE
  To study the correlation between obesity and clustering of major risk factors on cardiovascular disease in the elderly.
  
  
  METHODS
  A cross-sectional study was conducted. Data from 546 elderly aged 60-90 were analyzed for the relationship between obesity and clustering of risk factors for cardiovascular diseases, with descriptive statistical methods, chi2 test, logistic regression and ROC curve.
  
  
  RESULTS
  (1) The positive rates of the four major risk factors and clustering appeared an upward trend along with the BMI and/or the WC. The overall positive rate of clustering of risk factors among the total 546 elderly people was 59.5%, and 52.5% in males, 65.7% in females. (2) As compared with females, males had a higher growth rate of clustering with the elevating of BMI and WC, and odds ratios of the highest-level groups were 13.579 and 2.876 in males and females, respectively. (3) Both BMI and WC were independent influencing factors for male (P < 0.05), and logistic regression coefficients were 0.196 and 0.074 for BMI and WC, respectively. Only WC appeared to be the independent influencing factor for females (P < 0.05), while BMI was not (P = 0.537), with logistic regression coefficient as 0.060 for WC. (4) The combination equation of male's BMI and WC was CE(BMI + WC) = 0.726 x BMI + 0.274 x WC, with the optimum cut-off value as 41.59, and the sensitivity and the specificity were 0.785 and 0.598, respectively.
  
  
  CONCLUSIONS
  Four major risk factors for cardiovascular diseases were often related to obesity while control of BMI and WC were of great significance to the primary prevention of cardiovascular disease. The combined equation of BMI and WC could be used to predict the risk of clustering.
authors.affiliation: Department of Epidemiology and Statistics, School of Public Health, Peking University Health Science Center, Beijing 100083, China.
authors.forename: Wu-xiang
authors.initials: WX
authors.lastname: Xie
authors.forename: Wei-hua
authors.initials: WH
authors.lastname: Cao
authors.forename: Jun
authors.initials: J
authors.lastname: Lin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose; D001794:Blood Pressure; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology*; D016000:Cluster Analysis; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000453:epidemiology*; D012372:ROC Curve; D012307:Risk Factors; D055105:Waist Circumference
chemical_list: D001786:Blood Glucose