title: Structure elucidation and NMR assignments for three anthraquinone derivatives from the marine fungus Fusarium sp. (No. ZH-210).
abstract: The structure elucidations and complete (1)H and (13)C NMR assignments are reported for three new anthraquinone derivatives: Fusaquinon A (1), B (2), and C (3) isolated from the fermentation medium of the marine fungus Fusarium sp. (No. ZH-210). HREIMS, Fourier transform infrared absorption spectrometry (FT-IR), NMR experiments including gCOSY, gHMQC, gHMBC, and NOESY were used for the determination of the structures and NMR spectral assignments. Preliminary pharmacological test showed that they exhibited low cytotoxic activity towards KB, KBv200, and MCF-7 cell lines.
authors.affiliation: School of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, Guangzhou 510275, PR China.
authors.forename: Yiguang
authors.initials: Y
authors.lastname: Chen
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Cai
authors.forename: Jiahui
authors.initials: J
authors.lastname: Pan
authors.forename: Junping
authors.initials: J
authors.lastname: Gao
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Yuan
authors.forename: Liwu
authors.initials: L
authors.lastname: Fu
authors.forename: Zhigang
authors.initials: Z
authors.lastname: She
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Lin
mesh_terms: D000880:Anthraquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005670:Fusarium / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D012015:Reference Standards
chemical_list: C540512:1,4,5,6,7,9-hexahydroxy-2-methoxy-7-methyl-5,6,8,8a,9,10a-hexahydro-7,9-epoxyanthracen-10-one; C540513:1,4,6,7,9-pentahydroxy-2-methoxy-7-methyl-5,6,8,8a,9,10a-hexahydro-7,9-epoxyanthracen-10-one; C540511:1,4,6-trihydroxy-2-methoxy-7-methyl-5,6,8,8a,9,10a-hexahydro-7,9-epoxyanthracen-10-one; D000880:Anthraquinones