[Physiopathologic aspects of microcirculation in intensive care].
In critical care patients, microvascular alterations and perfusion heterogeneity play an important role in the persistence of cellular hypoxia despite a satisfactory functioning of the macrocirculation. Advance in the knowledge of microcirculatory pathophysiology, and its relation with the macrocirculation could be in the future a way to improve the outcome of critically ill patients. Moreover, the evolution of clinical practice towards microcirculation monitoring as a standard of care, with new therapeutic targets aimed to increase tissue perfusion, could be a revolution in critical care practice.
Siegenthaler
N
N
Service des soins intensifs, HUG, 1211 Genève 14.
Giraud
R
R
Romand
J-A
JA
Bendjelid
K
K
D001794:Blood Pressure / Q000502:physiology; D003422:Critical Care / Q000592:standards*; D006439:Hemodynamics; D006801:Humans; D008833:Microcirculation; D008991:Monitoring, Physiologic; D010101:Oxygen Consumption; D012772:Shock, Septic / Q000503:physiopathology*