Multi-angle LUCAS for high-throughput on-chip cytometry.
We illustrate that by recording under-sampled diffraction patterns of cells at different illumination angles, we can achieve high-throughput on-chip characterization of a heterogeneous cell solution over an ultra large volume of approximately 5 ml. This platform, termed multi-angle LUCAS, is especially promising for cost-effective point-of-care cell counting applications.
Su
Ting-Wei
TW
Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA. justinsu@ucla.edu
Seo
Sungkyu
S
Erlinger
Anthony
A
Ozcan
Aydogan
A
D001698:Biomedical Engineering; D002452:Cell Count / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D019044:Image Cytometry / Q000295:instrumentation / Q000379:methods*; D019095:Point-of-Care Systems; D012568:Schizosaccharomyces / Q000166:cytology