title: Interrelationships of quality of life, compliance, clinical outcomes and life satisfaction: a cross-sectional study on hypertensive geriatrics.
abstract: OBJECTIVE
  (i) To assess quality of life (QoL) profiles in hypertensive geriatrics with SF-36; (ii) to assess the compliance of geriatrics to medications; (iii) to estimate clinical outcomes (reduction in systolic and diastolic blood pressure); (iv) to assess life satisfaction and (v) to explore the interrelationships of QoL, compliance, clinical outcomes and life satisfaction in hypertensive geriatrics.
  
  
  METHODS
  Fifty-nine hypertensive geriatric patients in cardiology and 65 Plus clinics in West Virginia Hospitals were studied.
  
  
  RESULTS
  Age showed a significant negative correlation with physical functioning (r = 0.339, P< or =0.0127) and physical role (r=0.335, P< or =0.0148). The physical role facet of SF-36 is correlated with life satisfaction in geriatrics (r = 0.316, P < or =0.0219). A regression analysis (backward stepwise) not including bodily pain (BP) and general health (GH) resulted in a model explaining 22.3% of variance (n = 54, F = 2.252, P < or = 0.0543). Physical role (P < or = 0.0084) and mental health facets (P< or = 0.0184) of SF-36 emerged as the predictors of life satisfaction in elderly hypertensive patients. Emotional role functioning (P < or = 0.0257) and social functioning (P < or = 0.0033) scores predicted levels of diastolic blood pressure in elderly hypertensive patients. However, all eight concepts of SF-36 failed to predict compliance behaviour in geriatrics (n = 53, P < or = 0.6913, R2= 0.110).
authors.affiliation: College of Pharmacy and Pharmaceutical Sciences, Howard University, Washington, DC, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Pippalla
authors.forename: V
authors.initials: V
authors.lastname: Chinburapa
authors.forename: R
authors.initials: R
authors.lastname: Duval
authors.forename: R S
authors.initials: RS
authors.lastname: Akula
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D005260:Female; D006785:Hospitals, University; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D010549:Personal Satisfaction; D011788:Quality of Life; D012044:Regression Analysis; D016896:Treatment Outcome; D014903:West Virginia
chemical_list: D000959:Antihypertensive Agents