title: Intermolecular antiselective and enantioselective reductive coupling of enones and aromatic aldehydes with chiral Rh(Phebox) catalysts.
abstract: The intermolecular reductive coupling reaction of cyclopent-2-enone and aromatic aldehydes was realized by chiral rhodium-(bisoxazolinyl)phenyl catalysts, Rh(Phebox-Ph)(OAc)(2)(H(2)O), with diphenymethylsilane as a hydride donor to give the corresponding beta-hydroxyketones in high anti-selectivity (up to 96%) with high enantioselectivity (up to 93%).
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan.
authors.forename: Takushi
authors.initials: T
authors.lastname: Shiomi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Adachi
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Ito
authors.forename: Hisao
authors.initials: H
authors.lastname: Nishiyama