title: Patient with bilateral breast enlargement and hypospadias.
abstract: A 20 year old man was admitted in the surgical unit of Dhaka Medical College Hospital on August 2007 presented with Hypospadias & underdeveloped penis from childhood, gradual enlargement of both breasts for the last 10 years, absence of axillary and pubic hair from puberty & painful swelling of both testes for the last 3 years. The patient was regarded as a female upto the age of 10 years. He has got no voice change since puberty. On examination he had average body built, there was bilateral gynaecomastia, hypospadias, rudimentary penis & absence of pubic and axillary hair. His testosterone level, serum prolactin level, serum progesterone level, serum estradiol level was done. Cytology on buccal smear done and ultrasonography revealed no ovary and uterus. Ultimately patient was diagnosed as a case of androgen insensitivity syndrome (AIS). The case is reported for clinical awareness & to share our experience.
authors.affiliation: Department of Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh.
authors.forename: A A
authors.initials: AA
authors.lastname: Ali
authors.forename: T
authors.initials: T
authors.lastname: Ahmed
authors.forename: M M
authors.initials: MM
authors.lastname: Rashid
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D001941:Breast Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007021:Hypospadias / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008408:Mastectomy; D055815:Young Adult