title: SU-8 polymer enclosed microchannels with interconnect and nanohole arrays as an optical detection device for biospecies.
abstract: We present for the first time the integration of nanohole arrays for surface plasmon resonance (SPR) sensing together with SU-8 polymer microfluidic channels containing special packaging structures for chip-to-chip and world-to-chip interconnect. Primary steps towards an optical biospecies detection device are presented including observing the effect of period on transmission peak location, examining new materials for the enclosed microchannels, and demonstrating nanohole array SPR transmission data through water contained in the microchannels. Additionally, the enclosed microchannels are integrated with interconnect structures that facilitate interfacing with macro-scale test equipment and microfluidic components and systems such as lab-on-a-chip. Results demonstrate the potential of the polymer microchannels with integrated nanohole arrays and interconnect as a packaged optical SPR detection device.
authors.affiliation: Microinstrumentation Lab, Engineering Science, Simon Fraser University, BC V5A-1S6 Canada. bgray@ sfu.ca
authors.forename: S M
authors.initials: SM
authors.lastname: Westwood
authors.forename: B L
authors.initials: BL
authors.lastname: Gray
authors.forename: S
authors.initials: S
authors.lastname: Grist
authors.forename: K
authors.initials: K
authors.lastname: Huffman
authors.forename: S
authors.initials: S
authors.lastname: Jaffer
authors.forename: K L
authors.initials: KL
authors.lastname: Kavanagh
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004852:Epoxy Compounds / Q000737:chemistry*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D055096:Optical Devices; D011108:Polymers / Q000737:chemistry*; D016062:Porosity; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D020349:Surface Plasmon Resonance / Q000295:instrumentation* / Q000379:methods; D014159:Transducers
chemical_list: D004852:Epoxy Compounds; D011108:Polymers; C520895:SU-8 compound