Recurrent lower gastrointestinal bleeding secondary to cytomegalovirus-associated colonic ulcer in a non human immunodeficiency virus infected patient: timely diagnosis and treatment averted surgery.
Mr C, a 68-year-old Chinese male with diabetes mellitus, previous stroke and ischaemic cardiomyopathy on clopidogrel, presented with haematochezia. Colonoscopy showed a sigmoid ulcer, which was treated endoscopically. Histology of the biopsy from the ulcer revealed non-specific changes. However, he presented with recurrent bleeding from this non-healing sigmoid ulcer. A review of the histologic specimen revealed CMV intranuclear inclusion bodies. He was treated with intravenous ganciclovir, with no further hematochezia.
Lim
L-G
LG
Department of Gastroenterology and Hepatology, National University Hospital, Singapore. lee_guan_lim@nuhs.edu.sg
Rajnakova
A
A
Yan
B
B
Salto-Tellez
M
M
Lim
L-L
LL
D000368:Aged; D000998:Antiviral Agents; D001706:Biopsy; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D015774:Ganciclovir / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000821:virology*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D012810:Sigmoid Diseases / Q000821:virology*; D014456:Ulcer / Q000821:virology*
D000998:Antiviral Agents; D015774:Ganciclovir