title: Palladium-catalysed direct 3- or 4-arylation of 2,5-disubstituted pyrrole derivatives: an economically and environmentally attractive procedure.
abstract: Straight to the point: The direct 3- or 4-arylation of pyrrole derivatives through C--H bond activation proceeds in moderate to good yields using Pd(OAc)(2) as catalyst. In contrast to classical coupling procedures, the preparation of an organometallic derivative is not required and the major by-products are AcOH/KBr instead of metallic salts.
authors.affiliation: UMR CNRS-Université d'Aix-Marseille, France.
authors.forename: Yacoub
authors.initials: Y
authors.lastname: Fall
authors.forename: Henri
authors.initials: H
authors.lastname: Doucet
authors.forename: Maurice
authors.initials: M
authors.lastname: Santelli
mesh_terms: D002384:Catalysis; D055772:Green Chemistry Technology; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry* / Q000191:economics
chemical_list: D006841:Hydrocarbons, Aromatic; D011758:Pyrroles; D010165:Palladium