Retention and protocol adherence of Hispanic volunteers in a longitudinal trial.
OBJECTIVE
To compare Hispanic research volunteers with high and low levels of study retention and adherence.


METHODS
Correlational analysis of demographics, recruitment strategies, knowledge, and attitudes of 470 households in a clinical trial.


RESULTS
Within 12 months, 53 (11.3%) households dropped out; those less certain about some factual information were more likely to drop out (P < 0.05). Participants born outside the United States were more likely to adhere to protocols (P = 0.03). Flyers were effective for recruiting only 3% of participants.


CONCLUSIONS
In newly immigrated populations, written recruitment materials may be ineffective; knowledge and attitudes may be important for study retention and adherence.
Larson
Elaine L
EL
School of Nursing, Columbia University, New York, NY 10032, USA. ELL23@columbia.edu
Ferng
Yu-Hui
YH
Wong-McLoughlin
Jennifer
J
Wang
Shuang
S
D000328:Adult; D019983:Guideline Adherence; D006630:Hispanic or Latino; D006805:Human Experimentation; D006801:Humans; D008137:Longitudinal Studies; D009519:New York City; D010558:Personnel Loyalty; D012106:Research