title: Characterization of adrenal pheochromocytoma using respiratory-triggered proton MR spectroscopy: initial experience.
abstract: OBJECTIVE
  The aim of our study was to evaluate the feasibility of respiratory-triggered proton single-voxel MR spectroscopy for the diagnosis of adrenal pheochromocytoma and to determine whether certain spectral resonances detected on single-voxel MR spectroscopy are specific for adrenal pheochromocytomas compared with adrenal adenomas.
  
  
  CONCLUSIONS
  Adrenal pheochromocytomas have a unique MR spectral signature, showing 6.8 ppm resonance that is not seen in adenomas. This unique spectral signature may be attributed to the presence of catecholamines and catecholamine metabolites that are abundant in pheochromocytomas.
authors.affiliation: Department of Radiology, New York University Langone Medical Center, MRI, New York, NY 10016, USA.
authors.forename: Sooah
authors.initials: S
authors.lastname: Kim
authors.forename: Nouha
authors.initials: N
authors.lastname: Salibi
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Hardie
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.forename: Ruth P
authors.initials: RP
authors.lastname: Lim
authors.forename: Vivian S
authors.initials: VS
authors.lastname: Lee
authors.forename: Bachir
authors.initials: B
authors.lastname: Taouli
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D018246:Adrenocortical Adenoma / Q000175:diagnosis / Q000378:metabolism; D000328:Adult; D000368:Aged; D002395:Catecholamines / Q000378:metabolism; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000378:metabolism; D011446:Prospective Studies; D011522:Protons; D012119:Respiration
chemical_list: D002395:Catecholamines; D011522:Protons