Chemical modification of pseurotin A: one-pot synthesis of synerazol and pseurotin E and determination of absolute stereochemistry of pseurotin E.
Two natural products, synerazol and pseurotin E, were synthesized from the natural product pseurotin A in 58% and 57% yields, respectively in one-pot procedures. This work also establishes the absolute stereochemistry of pseurotin E.
Ishikawa
Minoru
M
Ninomiya
Tomohisa
T
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D011760:Pyrrolidinones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
D011760:Pyrrolidinones; C540756:pseurotin E; C068886:synerazol; C012013:pseurotin; D015107:4-Butyrolactone