title: Right ventricular outflow tract obstruction after bilateral lung transplantation.
abstract: We report here on the successful treatment for right ventricular outflow tract obstruction after bilateral lung transplantation in a patient with primary pulmonary hypertension. A 31-year-old female patient with primary pulmonary hypertension underwent successful bilateral lung transplantation. She had a pressure gradient of 30 mmHg through the right ventricular outflow tract one week after transplantation, but was successfully treated with atelenol and disopyramide. Long-term follow-up cardiac catheterization did not show any significant right ventricular outflow tract obstruction. The actual cause of the right ventricular outflow tract obstruction remained unknown, but longstanding pulmonary hypertension might have induced significant structural changes in the heart, such as right ventricular hypertrophy and enlargement.
authors.affiliation: Thoracic Surgery, Kyoto University, Kyoto, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Chen
authors.forename: N
authors.initials: N
authors.lastname: Hanaoka
authors.forename: S
authors.initials: S
authors.lastname: Hasegawa
authors.forename: T
authors.initials: T
authors.lastname: Fujinaga
authors.forename: T
authors.initials: T
authors.lastname: Shoji
authors.forename: H
authors.initials: H
authors.lastname: Sakai
authors.forename: T
authors.initials: T
authors.lastname: Bando
mesh_terms: D000328:Adult; D001262:Atenolol / Q000627:therapeutic use; D006348:Cardiac Surgical Procedures; D002317:Cardiovascular Agents / Q000627:therapeutic use; D004206:Disopyramide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000601:surgery*; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000601:surgery*; D016040:Lung Transplantation / Q000009:adverse effects*; D011859:Radiography; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
chemical_list: D002317:Cardiovascular Agents; D001262:Atenolol; D004206:Disopyramide