title: Vaccination of cattle against tropical theileriosis in Uzbekistan using autochthonous live vaccine.
abstract: In Uzbekistan, 1984 cattle were vaccinated with the TAU-219 autochthonous live Theileria annulata vaccine under field conditions. There were no post-vaccination reactions recorded in calves vaccinated with 10 times the recommended dose, under semi-field conditions. After vaccination 53.9% of the vaccinates developed fever over 39.5 degrees C that lasted for a few days, but none developed clinical theileriosis or required drug treatment during the 3-week follow-up. The numbers of animals in which piroplasms were detected before and after vaccination were similar (7.15% and 7.25%, respectively), indicating previous exposure to T. annulata tick infection. Following vaccination none of the 241 pregnant cows aborted. Milk production during 30-45 days was similar in non-vaccinated and vaccinated cows, at about 5.2-5.9L/day. During 1999-2006 a total of 11,000 field-grazing cattle were safely vaccinated in Uzbekistan.
authors.affiliation: Department of Protozoology, Institute of Zoology, Academy of Science, Tashkent, Uzbekistan. i.rasulov@rambler.ru
authors.forename: Ilhan
authors.initials: I
authors.lastname: Rasulov
authors.forename: L
authors.initials: L
authors.lastname: Fish
authors.forename: V
authors.initials: V
authors.lastname: Shkap
mesh_terms: D000034:Abortion, Veterinary / Q000453:epidemiology; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000517:prevention & control*; D005260:Female; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D016052:Protozoan Vaccines / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D016796:Theileria annulata / Q000276:immunology*; D013801:Theileriasis / Q000469:parasitology / Q000517:prevention & control*; D016896:Treatment Outcome; D014610:Uzbekistan / Q000453:epidemiology; D014611:Vaccination / Q000662:veterinary; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology
chemical_list: D016052:Protozoan Vaccines; D014613:Vaccines, Attenuated