title: The Chinese QOLIE-AD-48: translation, validity, and reliability.
abstract: The aim of this study was to translate into Chinese the Quality of Life in Epilepsy Inventory for Adolescents (QOLIE-AD-48) and to evaluate its psychometric properties. After a multistage translation and cultural adaptation, the final Chinese version was administered to 99 adolescents with epilepsy to evaluate its validity and reliability. Interitem correlations, correlations with the Pediatric Quality of Life Inventory (PedsQL), internal consistency, and sensitivity were examined. Mean total score was 66.1, and all subscales contributed significantly to the summary measure. Considering the validity of the translation, each item correlated more significantly with its own subscale than with the other subscales, whereas all subscales were substantially correlated with the PedsQL subscales (r=0.73). The internal consistency coefficients of the subscales ranged between 0.62 and 0.92, and this coefficient was 0.94 for the total. Finally, the QOLIE-AD-48 could detect differences in quality of life between the subjects. In conclusion, this study showed that the Chinese QOLIE-AD-48 possesses good validity, reliability, and sensitivity, and is an appropriate instrument for health-related quality of life assessment in Chinese adolescents with epilepsy.
authors.affiliation: Epilepsy Center, Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences Peking Union Medical College, 1 Shuai Fu Yuan, Dong Dan, Beijing 100730, China.
authors.forename: Mengyang
authors.initials: M
authors.lastname: Wang
authors.forename: Liwen
authors.initials: L
authors.lastname: Wu
authors.forename: Yu
authors.initials: Y
authors.lastname: Zheng
authors.forename: Quan
authors.initials: Q
authors.lastname: Zhang
authors.forename: Cheng
authors.initials: C
authors.lastname: Li
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D002681:China; D003469:Culture; D004827:Epilepsy / Q000145:classification / Q000209:etiology / Q000523:psychology*; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
chemical_list: D000927:Anticonvulsants