Coronary heart disease risk reduction intervention among overweight smokers with a psychotic disorder: pilot trial.
OBJECTIVE
The aim of the present pilot study was to test the feasibility and short-term impact of a multi-component risk factor intervention for reducing (i) coronary heart disease (CHD) risk; (ii) smoking; and (iii) weight among smokers with psychosis. Secondary dependent variables included physical activity, unhealthy eating, substance use, psychiatric symptomatology, treatment retention, general functioning, and quality of life.


METHODS
This was a feasibility study utilizing a pre-post-treatment design with no control group (n=43). All participants provided written informed consent and were assessed before treatment and again a mean of 19.6 weeks later. The treatment consisted of nine individual 1h sessions of motivational interviewing and cognitive behaviour therapy plus nicotine replacement therapy, in addition to treatment as usual. Research assistants who had not been involved in the delivery of the treatment programme conducted post-treatment assessments.


RESULTS
The intervention was associated with significant reductions in CHD risk scores, smoking and weight. A significant improvement was also reported in level of moderate physical activity, and a small change in the unhealthy eating index was reported. No improvement in biological measures (cholesterol and blood pressure) was evident.


CONCLUSIONS
A multi-component CHD risk factor intervention among smokers with psychosis appears to be feasible and effective in the short-term. A randomized controlled trial replicating and extending these findings is warranted.
Baker
Amanda
A
Centre for Brain and Mental Health Research, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia. amanda.baker@newcastle.edu.au
Richmond
Robyn
R
Castle
David
D
Kulkarni
Jayashri
J
Kay-Lambkin
Frances
F
Sakrouge
Rebecca
R
Filia
Sacha
S
Lewin
Terry J
TJ
D000287:Administration, Topical; D000328:Adult; D015928:Cognitive Behavioral Therapy; D003327:Coronary Disease / Q000453:epidemiology* / Q000517:prevention & control*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008019:Life Style; D008297:Male; D009043:Motor Activity; D009538:Nicotine / Q000627:therapeutic use; D009765:Obesity / Q000453:epidemiology*; D010865:Pilot Projects; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D012307:Risk Factors; D012720:Severity of Illness Index; D012907:Smoking / Q000453:epidemiology*; D016540:Smoking Cessation / Q000379:methods; D000074606:Smoking Prevention; D011795:Surveys and Questionnaires
D009538:Nicotine