Antiphospholipid antibody syndrome leading to massive pulmonary embolism and sudden death.
Antiphospholipid antibody syndrome is associated with venous and arterial thromboembolism. Coexistence of pulmonary embolism and intracardiac thrombus is rarely encountered. A 33-year-old male patient presented with severe dyspnea three months after surgery for acute arterial embolism. On physical examination, blood pressure was 80/60 mmHg and breath sounds were weaker in the lower zone of the left lung. Severe lower limb edema was noted. On cardiac auscultation, the third heart sound was elicited. Electrocardiography showed only a sinusal tachycardia. Transthoracic echocardiography revealed a huge thrombus in the right atrium and another thrombus in the main pulmonary artery. Hematological analysis showed a high titration of antiphospholipid antibodies. A diagnosis of massive pulmonary embolism was considered. During preparation for emergency operation, the patient developed cardiovascular collapse, which did not respond to cardiopulmonary resuscitation.
Gündoğdu
Fuat
F
Department of Cardiology, Medicine Faculty of Atatürk University, Erzurum, Turkey. gundogdudr@gmail.com
Unlü
Yahya
Y
Bariş
Nezihi
N
Arslan
Sakir
S
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000401:mortality; D003645:Death, Sudden / Q000209:etiology*; D004452:Echocardiography; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000209:etiology* / Q000401:mortality