Pregnancy in true hermaphrodites and all male offspring to date.
BACKGROUND
There are 11 reported cases of pregnancy in true hermaphrodites, but none with advanced genetic testing. All known fetuses have been male.


METHODS
A true hermaphrodite with a spontaneous pregnancy prenatally known to have a remaining portion of a right ovotestis, delivered a male neonate. The mother has a 46, XX karyotype with polymerase chain reaction demonstrating low levels of the Yq12 sequence. Postpartum androgen levels were normal.


CONCLUSIONS
Partial removal of testicular tissue may enhance fertility in hermaphrodites, and there may be a genetic basis for the progeny to be male.
Schultz
Brett A H
BAH
From the Department of Obstetrics and Gynecology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio.
Roberts
Soldrea
S
Rodgers
Allison
A
Ataya
Khalid
K
D000328:Adult; D000649:Amniocentesis; D005260:Female; D006801:Humans; D006869:Hydronephrosis; D007231:Infant, Newborn; D008297:Male; D016104:Oligohydramnios; D010053:Ovary / Q000648:ultrastructure*; D050090:Ovotesticular Disorders of Sex Development / Q000235:genetics*; D011247:Pregnancy; D012732:Sex Determination Analysis; D047929:Term Birth; D013737:Testis / Q000648:ultrastructure*