Terpenes from Eupatorium adenophorum and their allelopathic effects on Arabidopsis seeds germination (dagger).
The invasive plant Eupatorium adenophorum Spreng. (or Ageratina adenophora (Spreng.) King and Robinson) (Compositae) has caused great economic loss in China, especially the southwestern region, and is gravely threatening the native biodiversity. The aerial part of this plant was phytochemically investigated for its allelochemicals. Eleven terpenes (2 monoterpenes and 9 sesquiterpenes) were isolated and identified, which include a new monoterpene, (-)-(1R*,2S,*4R*,5S*)-3,3-dimethyl-5-hydroxybicyclo[2,2,1]hept-2-ylmethanol (1), two new cadinane sesquiterpenes, (-)-(5S*,6S*,7S*,9R*,10S*)-7-hydroxy-5,7-epidioxycadinan-3-ene-2-one (2) and (+)-(5S*,6R*,9R*,10S*)-5,6-dihydroxycadinan-3-ene-2,7-dione (3), and eight known terpene compounds (4, 6-12). The new structures were established by spectroscopic studies such as 1D- and 2D-NMR and MS analyses. Meanwhile, the potential allelopathic effects of these compounds on the Arabidopsis seeds germination were tested. Compounds 3 and 7 retarded the Arabidopsis seeds germination at 0.5 mM and 1.0 mM concentrations, respectively, while other compounds showed no obvious inhibitory effects.
Zhao
Xu
X
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming.
Zheng
Guo-Wei
GW
Niu
Xue-Mei
XM
Li
Wei-Qi
WQ
Wang
Fu-Sheng
FS
Li
Sheng-Hong
SH
D036603:Ageratina / Q000737:chemistry*; D017360:Arabidopsis / Q000187:drug effects* / Q000502:physiology; D018525:Germination / Q000187:drug effects*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
D010936:Plant Extracts; D013729:Terpenes