Change in live donor characteristics over the last 25 years: a single centre experience.
OBJECTIVE
While deceased donor kidney transplantation rates have remained stagnant, live donor kidney transplantation (LDKT) rates have increased significantly over the last decade, and are now a major component of renal transplantation programmes worldwide. Additionally, there has been an increased utilization of more marginal donors, including donors who are obese, older and subjects with well-controlled hypertension.


METHODS
A retrospective audit of all live donors at the Princess Alexandra Hospital Renal Transplantation unit was performed from 24 August 1982 to 29 May 2007 to assess any change in donor characteristics over time.


RESULTS
There were 373 live donor operations. Over the last 25 years there has been a significant increase in the number of donors who are either older or obese. Furthermore, there is a greater proportion of spousal and emotionally related LDKT.


CONCLUSIONS
It is imperative that donors, in particular marginal donors, are followed up long-term to determine their risk of kidney and cardiovascular disease and initiation of appropriate treatment if required.
Kaisar
Mohd O
MO
Department of Renal Transplantation, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Nicol
David L
DL
Hawley
Carmel M
CM
Mudge
David W
DW
Johnson
David W
DW
Preston
John M
JM
Wall
Daryl R
DR
Griffin
Anthony D
AD
Campbell
Scott B
SB
Isbel
Nicole M
NM
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies