title: Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine.
authors.forename: Nuggehally R
authors.initials: NR
authors.lastname: Srinivas
mesh_terms: D003533:Cyproheptadine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000378:metabolism; D051544:Cytochrome P-450 CYP3A / Q000235:genetics*; D039563:Histamine H1 Antagonists, Non-Sedating / Q000009:adverse effects / Q000378:metabolism*; D006801:Humans; D017336:Loratadine / Q000031:analogs & derivatives* / Q000378:metabolism; D009154:Mutation; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: D039563:Histamine H1 Antagonists, Non-Sedating; C103639:rupatadine; D003533:Cyproheptadine; D017336:Loratadine; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; C121345:desloratadine