title: Bilateral vocal cord paralysis following treatment with vincristine.
abstract: The neurotoxicity of the vincristine is well known, however, cranial neuropathy is not widely recognized. We describe a child with acute lymphoblastic leukemia who developed vincristine-induced bilateral vocal cord paralysis. Vocal cord paralysis resolved spontaneously upon withdrawal of the vincristine. Vinca-alkaloid-induced vocal cord paralysis is a potentially dangerous but reversible condition.
authors.affiliation: Department of Hematology, All India Institute of Medical Sciences, New Delhi 110 029, India. dr_rahul6@hotmail.com
authors.forename: Rahul
authors.initials: R
authors.lastname: Naithani
authors.forename: Tuphan Kanti
authors.initials: TK
authors.lastname: Dolai
authors.forename: Rajat
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000293:Adolescent; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D014750:Vincristine / Q000009:adverse effects* / Q000627:therapeutic use; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine