Siderocalins: siderophore-binding proteins of the innate immune system.
Recent studies have revealed that the mammalian immune system directly interferes with siderophore-mediated iron acquisition through siderophore-binding proteins and that the association of certain siderophores, or siderophore modifications, with virulence is a direct response of pathogens to evade these defenses.
Clifton
Matthew C
MC
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Corrent
Colin
C
Strong
Roland K
RK
D000818:Animals; D006801:Humans; D007113:Immunity, Innate / Q000502:physiology*; D054834:Lipocalins / Q000737:chemistry* / Q000378:metabolism* / Q000502:physiology; D011485:Protein Binding / Q000235:genetics / Q000502:physiology; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D017262:Siderophores / Q000378:metabolism*
D054834:Lipocalins; D017262:Siderophores