Novel N-containing rotenoid and seco-rotenoid from the root of Derris elliptica.
Two new rotenoids, 2-hydroxy-5-aminorotenonone (1) and elliptoic acid (2), were isolated from the roots of Derris elliptica collected in Guangdong Province, China. Their structures were established by extensive spectral analysis. Compound 1 is the first N-containing rotenoid and compound 2 is the third rotenoid with the cleavage of C(12)-C(12a).
Lu
Hai-Ying
HY
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Liang
Jing-Yu
JY
D029866:Derris / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D012402:Rotenone / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*
C539410:2-hydroxy-5-aminorotenonone; D004365:Drugs, Chinese Herbal; C539411:elliptoic acid; D012402:Rotenone