Understanding the words of chromatin regulation.
Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.
Wu
Jiang I
JI
Howard Hughes Medical Institute, Departments of Pathology and Developmental Biology, Stanford University, Stanford, CA 94062, USA.
Lessard
Julie
J
Crabtree
Gerald R
GR
D000818:Animals; D042002:Chromatin Assembly and Disassembly; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D005786:Gene Expression Regulation; D042421:Histone Code; D006801:Humans; D014714:Vertebrates / Q000235:genetics
D002868:Chromosomal Proteins, Non-Histone