title: Are unadjusted analyses of clinical trials inappropriately biased toward the null?
authors.forename: David M
authors.initials: DM
authors.lastname: Kent
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Trikalinos
authors.forename: Michael D
authors.initials: MD
authors.lastname: Hill
mesh_terms: D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D016208:Databases, Factual; D006801:Humans; D017711:Nonlinear Dynamics; D016017:Odds Ratio; D016032:Randomized Controlled Trials as Topic; D012107:Research Design / Q000639:trends*; D020379:Risk Adjustment; D020521:Stroke / Q000628:therapy*