title: Elevated transrenal DNA (cell-free urine DNA) in patients with urinary tract infection compared to healthy controls.
abstract: OBJECTIVE
  To study whether levels of transrenal DNA (Tr-DNA) are influenced by the presence of urinary tract infections (UTI).
  
  
  METHODS
  Tr-DNA concentrations were measured in 124 donors and 55 patients with UTI. Two methods for DNA extraction were compared.
  
  
  RESULTS
  UTI patients showed higher concentrations than the donors (normal range: 0-147 GE/mL). QIAamp MiniElute Virus Spin Kit was more efficient than QIAamp DNA Blood Mini Kit.
  
  
  CONCLUSIONS
  Increased concentrations of Tr-DNA urine DNA are shown in presence of UTI.
authors.affiliation: Servicio de Bioquímica Clínica, Hospital Universitario Central de Asturias, Spain.
authors.forename: Vanessa
authors.initials: V
authors.lastname: García Moreira
authors.forename: Belén
authors.initials: B
authors.lastname: Prieto García
authors.forename: Tamara
authors.initials: T
authors.lastname: de la Cera Martínez
authors.forename: Francisco V
authors.initials: FV
authors.lastname: Alvarez Menéndez
mesh_terms: D000328:Adult; D000368:Aged; D004247:DNA / Q000652:urine*; D006801:Humans; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014552:Urinary Tract Infections / Q000652:urine*; D055815:Young Adult
chemical_list: D004247:DNA