Light-operated mechanized nanoparticles.
Mesoporous silica (MCM-41) nanoparticles modified by azobenzene derivatives, capable of storing small molecules and releasing them following light irradiation, have been fabricated and characterized. In the presence of the beta-cyclodextrin and/or pyrene-modified beta-cyclodextrin rings, the beta-cyclodextrin and/or pyrene-modified beta-cyclodextrin rings will thread onto the azobenzene-containing stalks and bind to trans-azobenzene units to form the pseudorotaxanes, thus sealing the nanopores and stopping release of the cargo. Upon irradiation, the isomerization of trans-to-cis azobenzene units leads to the dissociation of the beta-cyclodextrin and/or pyrene-modified beta-cyclodextrin rings from the stalks, thus opening the gates to the nanopores and releasing the cargo.
Ferris
Daniel P
DP
Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095-1569, USA.
Zhao
Yan-Li
YL
Khashab
Niveen M
NM
Khatib
Hussam A
HA
Stoddart
J Fraser
JF
Zink
Jeffrey I
JI
D001391:Azo Compounds / Q000737:chemistry*; D003692:Delayed-Action Preparations; D008027:Light; D008163:Luminescent Measurements; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D055668:Photochemical Processes; D011721:Pyrenes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
D001391:Azo Compounds; D003692:Delayed-Action Preparations; C509968:MCM-41; D011721:Pyrenes; D047392:beta-Cyclodextrins; D012822:Silicon Dioxide; C009850:azobenzene; C031215:betadex