title: Case of lacrimal gland inflammation associated with ulcerative colitis.
abstract: We report a case of lacrimal gland pseudotumor as the presenting sign of ulcerative colitis. A 25-year-old woman presented with a right upper eyelid swelling and pain. Intravenous administration of prednisolone was initiated on suspicion of lacrimal gland inflammation (pseudotumor). Although the treatment markedly reduced her ocular symptoms, she developed lower abdominal cramping and diarrhea with the 5 mg/day of oral prednisolone. Sigmoid colonoscopy and colon biopsy led to make a diagnosis of ulcerative colitis. Ulcerative colitis improved significantly with increased dose of steroid and additive mesalazine therapy. Ulcerative colitis should be included in the differential diagnosis of lacrimal gland pseudotumor.
authors.affiliation: Department of Ophthalmology, JA Gifu Koseren, Chuno General Hospital, Gifu, Japan.
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Akira
authors.initials: A
authors.lastname: Sawada
authors.forename: Naoki
authors.initials: N
authors.lastname: Katsumura
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects; D003085:Colic / Q000209:etiology; D003093:Colitis, Ulcerative / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003607:Dacryocystitis / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D007765:Lacrimal Apparatus / Q000187:drug effects / Q000473:pathology* / Q000503:physiopathology; D010146:Pain; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects; D012812:Sigmoidoscopy
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone