Can cetuximab affect paraneoplastic myopathy?
Cetuximab given concurrently with chemotherapy has shown survival benefit for patients with metastatic colon cancer. We report a case of a patient with metastatic colon cancer who developed paraneoplastic necrotizing myopathy that possibly responded to cetuximab despite lack of improvement of the underlying cancer.
Galani
Eleni
E
Second Oncology Department, Metropolitan Hospital, Athens, Greece.
Bonakis
Anastasios
A
Christodoulou
Christos
C
Klouvas
George
G
Drougou
Angeliki
A
Angeliki
Drougou
D
Skarlos
Dimostenis
D
D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy / Q000556:secondary; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy; D000068818:Cetuximab; D003110:Colonic Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D000077146:Irinotecan; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy; D008113:Liver Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009135:Muscular Diseases / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D010257:Paraneoplastic Syndromes / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D014376:Tuberculosis / Q000150:complications / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D000077146:Irinotecan; D000068818:Cetuximab; D008775:Methylprednisolone; D002166:Camptothecin