An urticarial vasculitis case induced by glatiramer acetate.
Urticarial vasculitis (UV) is a disease characterized clinically by urticarial skin lesions and histologically by leukocytoclastic vasculitis caused by immunocomplex accumulation in post-capillary venules. Cases induced by various drugs such as cimetidine, diltiazem, potassium iodide, fluoxetine, and non-steroid inflammatory drugs have been reported in the literature. A 48-year-old female who developed pruritus and rash on her body 3 months after starting glatiramer acetate (GA) treatment for multiple sclerosis was diagnosed with UV after clinical and histopathological examination. This report presents the first case in the literature of UV induced by GA.
Cicek
Demet
D
Department of Dermatology, Firat University Faculty of Medicine, Elazig, Turkey. dr.demetcicek@yahoo.com
Kandi
Basak
B
Oguz
Sevilay
S
Cobanoglu
Bengu
B
Bulut
Serpil
S
Saral
Yunus
Y
D005260:Female; D000068717:Glatiramer Acetate; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy*; D010455:Peptides / Q000009:adverse effects*; D014581:Urticaria / Q000139:chemically induced*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced*
D007166:Immunosuppressive Agents; D010455:Peptides; D000068717:Glatiramer Acetate