title: Candidate's Thesis: Laryngotracheal separation in neurologically impaired children: long-term results.
abstract: OBJECTIVE
  Fifty-six consecutive neurologically impaired pediatric children underwent laryngotracheal separation (LTS) for acute recurrent and chronic aspiration in the last 18 years. The population demographics, indications for surgery, and comorbidities are reviewed. This study reports early and late complications and survivorship including admissions for pneumonia/aspiration. Diagnosis related group (DRGs) and work relative value units (wRVUs) were measured to document the potential benefits before and after LTS.
  
  
  METHODS
  Retrospective review of patient charts and records in an electronic medical record during an 18 year period.
  
  
  METHODS
  Information was obtained by a chart review and utilization of the electronic medical record. Patient specific DRG and wRVU data on their hospitalizations and outpatient encounters at the Alfred I. duPont Hospital for Children of the Nemours Foundation and survival data were recorded. Data was analyzed using chi-square analysis, a two-tailed t test, and a Fisher's Exact test.
  
  
  RESULTS
  Laryngotracheal separation achieved complete control of aspiration in all the children. A significant reduction in the number of hospital admissions for pneumonias after surgery was noted. After LTS there was a reduced average number of DRGs per month (p < .001) as well as wRVUs. Transient fistula formation (11%) was the most common complication. No patient had his or her procedure reversed to date.
  
  
  CONCLUSIONS
  Laryngotracheal separation is 100% effective in controlling aspiration in all of neurologically impaired children in this study, It is a valuable procedure to prolong the life of children who have intractable aspiration. After LTS, a decrease in DRGs and wRVUs reduces health care costs for these patients. Prior to LTS, all medical and surgical treatment options for aspiration should be discussed and considered, based on the extent of the child's underlying neurologic status, ability to verbally communicate, degree of upper airway obstruction, and hope of recovery of neurologic function.
authors.affiliation: Division of Pediatric Otolaryngology, Alfred I duPont Hospital for Children, Nemours Children's Clinic, Wilmington, DE 19803, USA. scook@nemours.org
authors.forename: Steven P
authors.initials: SP
authors.lastname: Cook
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003680:Deglutition Disorders / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D007830:Larynx / Q000601:surgery*; D008297:Male; D009422:Nervous System Diseases / Q000150:complications*; D011015:Pneumonia, Aspiration / Q000517:prevention & control*; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate; D014132:Trachea / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult