title: Novel acylated lipo-oligosaccharides from the tubers of Ipomoea batatas.
abstract: Nine new lipo-oligosaccharides, batatosides H-P, were isolated from the tubers of Ipomoea batatas (Convolvulaceae). Spectral and chemical methods allowed to characterize them as tetra- or penta-saccharides that form a macrolactone with the aglycone, (11S)-hydroxyhexadecanoic acid (jalapinolic acid), the absolute configuration of which was established by Mosher's method. Batatosides L and O showed a weak inhibitory effect on the growth of Hep-2 cells, while the others proved to be inactive.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, People's Republic of China.
authors.forename: Yong-Qin
authors.initials: YQ
authors.lastname: Yin
authors.forename: Jun-Song
authors.initials: JS
authors.lastname: Wang
authors.forename: Jian-Guang
authors.initials: JG
authors.lastname: Luo
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
mesh_terms: D002240:Carbohydrate Sequence; D002460:Cell Line; D006801:Humans; D027723:Ipomoea batatas / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009844:Oligosaccharides / Q000737:chemistry*; D035281:Plant Tubers / Q000737:chemistry*
chemical_list: D008070:Lipopolysaccharides; D009844:Oligosaccharides