title: Oral formulations of budesonide: a novel treatment for inflammatory bowel disease.
abstract: Budesonide is a promising drug for a variety of documented applications and has potential in gastroenterology. Its unique local mechanism of delivery and efficient first-pass metabolism, resulting in fewer systemic adverse effects than with conventional glucocorticoids, makes this a desirable drug for clinical practice. This drug has shown promise in treating a wide spectrum of inflammatory diseases from inflammatory bowel disease and other colitides to autoimmune liver diseases. Future research should focus on ways to increase delivery methods to promote long-term usage for maintenance therapy for the disease entities listed above, as well as for other potential nongastrointestinal conditions.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
authors.forename: R Paul
authors.initials: RP
authors.lastname: Svoboda
authors.forename: Dhaval H
authors.initials: DH
authors.lastname: Patel
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Olden
mesh_terms: D000284:Administration, Oral; D019819:Budesonide / Q000008:administration & dosage* / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000737:chemistry; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000737:chemistry; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy* / Q000503:physiopathology; D015394:Molecular Structure
chemical_list: D003692:Delayed-Action Preparations; D005938:Glucocorticoids; D019819:Budesonide