title: Flexible polymer substrate and tungsten microelectrode array for an implantable neural recording system.
abstract: This paper describes the process flow and testing of a substrate for a fully implantable neural recording system. Tungsten microwires are hybrid-packaged on a micromachined flexible polymer substrate forming an intracortical microelectrode array for brain machine interfaces. The microelectrode array is characterized on the bench top and tested in vivo. The microelectrode noise floor is less than 2 microV and acute recording results show a signal to noise ratio of 9.9-17.3 dB. The technique of hybrid fabrication of the electrodes on a flexible substrate provides a general platform for the development of an implantable neural recording system.
authors.affiliation: Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA. ee1@ufl.edu
authors.forename: Erin
authors.initials: E
authors.lastname: Patrick
authors.forename: Viswanath
authors.initials: V
authors.lastname: Sankar
authors.forename: William
authors.initials: W
authors.lastname: Rowe
authors.forename: Sheng-Feng
authors.initials: SF
authors.lastname: Yen
authors.forename: Justin C
authors.initials: JC
authors.lastname: Sanchez
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Nishida
mesh_terms: D000465:Algorithms; D000818:Animals; D001672:Biocompatible Materials; D004566:Electrodes; D004567:Electrodes, Implanted; D004594:Electrophysiology / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D008297:Male; D008904:Miniaturization; D015233:Models, Statistical; D011108:Polymers / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014414:Tungsten / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D014414:Tungsten