Effects of magnetic fields on intracellular calcium oscillations.
Based on the model of the two calcium stores developed by Goldbeter, and the viewpoint that the cell membrane is a major site of interaction for extremely-low-frequency (ELF) electromagnetic fields, the permeability of ions can be changed by electromagnetic fields, a theoretical model of cytosolic calcium oscillations influenced by magnetic fields is presented. It is shown that, the field frequency condition will influence the pattern of calcium oscillation while the field strength was given, and the magnetic field strength will change the pattern of calcium oscillation when the frequency was 50Hz and 100Hz. Therefore, intracellular calcium oscillations can be influenced by ELF magnetic fields and then a series cellular response could be transformed.
Zhao
Yong-Li
YL
School of Mechanical and Electronic Engineering, Tianjin Polytechnic University, Tianjin 300130, China.
Yang
Jian-Chen
JC
Zhang
Yu-Hong
YH
D020013:Calcium Signaling / Q000528:radiation effects*; D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects; D003600:Cytosol / Q000378:metabolism* / Q000528:radiation effects; D004574:Electromagnetic Fields; D008954:Models, Biological