title: Clinical characteristics of benign convulsions with rotavirus gastroenteritis.
abstract: Convulsions sometimes occur in infants and toddlers with mild gastroenteritis. We retrospectively investigated the hospital records of 106 patients admitted to our hospital who had rotavirus gastroenteritis from February 2002 to April 2008. There were 23 patients with convulsions, including 13 with benign convulsions, 9 with febrile seizures, and 1 with epilepsy. Gastroenteritis in patients with benign convulsions was mild from the viewpoint of body weights and serum creatinine concentrations on admission and the duration of admission. Serum Na(+) and Cl(-) concentrations of patients with benign convulsions were relatively lower than those without convulsions on admission (P = .006, and P = .008, respectively). Twelve of thirteen patients had no other seizures after oral administration of 5 mg/kg of carbamazepine, while 1 patient had 1 convulsion 15 minutes after the therapy. In conclusion, carbamazepine therapy was effective for benign convulsions with rotavirus gastroenteritis.
authors.affiliation: Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Motoyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Ichiyama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Matsushige
authors.forename: Madoka
authors.initials: M
authors.lastname: Kajimoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shiraishi
authors.forename: Susumu
authors.initials: S
authors.lastname: Furukawa
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D001835:Body Weight; D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002712:Chlorides / Q000097:blood; D003404:Creatinine / Q000097:blood; D005260:Female; D005759:Gastroenteritis / Q000150:complications*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D012400:Rotavirus Infections / Q000150:complications*; D012640:Seizures / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D003294:Seizures, Febrile / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D012964:Sodium / Q000097:blood
chemical_list: D000927:Anticonvulsants; D002712:Chlorides; D002220:Carbamazepine; D012964:Sodium; D003404:Creatinine