title: Adverse consequences of the 50% misconception.
abstract: It is often claimed that only 50% of the incidence of coronary artery disease in the population can be attributed to the standard major risk factors. A careful review of published research demonstrates that 75% to 90% of coronary artery disease incidence in a variety of populations is explained by the standard modifiable risk factors. In conclusion, these data suggest that a more rigorous focus on these conventional risk factors and the lifestyle behaviors that promote them has great potential to reduce the burden of coronary artery disease worldwide.
authors.affiliation: Framingham Heart Study, Framingham, MA, USA. billkannel@yahoo.com
authors.forename: William B
authors.initials: WB
authors.lastname: Kannel
authors.forename: Ramachandran S
authors.initials: RS
authors.lastname: Vasan
mesh_terms: D000368:Aged; D003327:Coronary Disease / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D040242:Risk Reduction Behavior