title: Subepithelial pelvic hematoma (Antopol--Goldman lesion) simulating renal neoplasm: report of a case and review of the literature.
abstract: The Antopol-Goldman lesion is a subepithelial pelvic hematoma simulating a renal neoplasm. We report the clinico-pathological features of a single case and a review of the literature. A 76-year-old man presented with flank pain and hematuria. Computed tomography showed a hypodense lesion of 6 cm at the left kidney with filling defect at pyelogram. The patient underwent nephroureterectomy for suspected neoplasm. Macroscopically, a mass of 6 cm was present impinging on the pelvi-caliceal system. Microscopically, the lesion was composed by hemorragic material with feature of an hematoma. A diffuse eosinophilic amorphous material suspicious for amyloid was observed among intra- and extraparenchymal vessels. The Congo-Red staining verified the presence of amyloid. The diagnosis was subepithelial pelvic hematoma with severe amyloidosis. Antopol-Goldman lesion should be kept in mind as a possible differential diagnosis of upper urinary tract lesion to avoid unnecessary nephrectomies. The anamnestic knowledge of amiloydosis may increase this diagnostic hypothesis.
authors.affiliation: Department of Pathology, Ospedale Civile Maggiore, Verona, Italy. albatax@libero.it
authors.forename: Albino
authors.initials: A
authors.lastname: Eccher
authors.forename: Matteo
authors.initials: M
authors.lastname: Brunelli
authors.forename: Stefano
authors.initials: S
authors.lastname: Gobbo
authors.forename: Claudio
authors.initials: C
authors.lastname: Ghimenton
authors.forename: Gaetano
authors.initials: G
authors.lastname: Grosso
authors.forename: Antonio
authors.initials: A
authors.lastname: Iannucci
authors.forename: Paolo
authors.initials: P
authors.lastname: Dalla Palma
authors.forename: Fabio
authors.initials: F
authors.lastname: Menestrina
authors.forename: Guido
authors.initials: G
authors.lastname: Martignoni
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D006406:Hematoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D007682:Kidney Pelvis / Q000473:pathology* / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed