Two new steroidal saponins from the rhizome of Polygonatum sibiricum.
Two new furostanol saponins, polygonoides A (1) and B (2), along with three known compounds, were obtained from the ethanolic extract of the rhizome of Polygonatum sibiricum Redoute. On the basis of acid hydrolysis and comprehensive spectroscopic analyses, the structures of polygonoides A and B were elucidated as (25R)-26-O-beta-D-glucopyranosyl-furost-5,22(23)-dien-3beta,26-diol-3-O-alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranosyl-(1 --> 4)-[alpha-L-rhamnopyranosyl-(1 --> 2)]-beta-D-glucopyranoside (1) and 22 alpha-(propionyloxy)-furost-5-en-3beta,20 alpha-diol-3-O-beta-D-glucopyranosyl-(1 --> 4)-[alpha-L-rhamnopyranosyl-(1 --> 2)]-beta-D-glucopyranoside (2).
Xu
De-Ping
DP
School of Food Science and Technology, Research Center of Natural Products, Jiangnan University, Wuxi, China. xdp1219@yahoo.com.cn
Hu
Chang-Ying
CY
Zhang
Yang
Y
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D031384:Polygonatum / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
D004365:Drugs, Chinese Herbal; D010840:Phytosterols; D012503:Saponins; C539205:polygonoide A; C539206:polygonoide B