title: [Diagnostic pitfall: basal cell carcinoma arising in a therapy-resistant chronic venous ulcer of the lower leg].
abstract: METHODS
  A 96-year-old woman attended our department with an ulcer on the lower leg. It looked typical of an ulcer due to chronic venous insufficiency an had been resistant to treatment for 20 years.
  
  
  METHODS
  On the left lower leg there was a 5 x 5 cm ulcer with a sharply demarkated border. Because of its chronicity and its resistance to treatment several biopsies were taken from its borders.
  
  
  METHODS
  Histopathologically examination revealed a basal cell carcinoma. The ulcer was excised with a wide margin and the wound closed with a mesh-graft.
  
  
  CONCLUSIONS
  This case demonstrates the need of re-evaluating the pathology of chronic ulcers due to venous stasis in the leg to exclude malignancy.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, München, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Boneberger
authors.forename: T
authors.initials: T
authors.lastname: Ruzicka
authors.forename: R A
authors.initials: RA
authors.lastname: Rupec
mesh_terms: D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000601:surgery; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014689:Venous Insufficiency / Q000150:complications