title: [The clinical usefulness of focally enhanced gastritis in Korean patients with Crohn's disease].
abstract: OBJECTIVE
  Focally enhanced gastritis (FEG) has been suggested as a specific diagnostic marker for patients with Crohn's disease (CD). However, the usefulness of FEG for distinguishing CD from ulcerative colitis (UC) is uncertain and the incidence or prevalence of FEG for inflammatory bowel disease (IBD) patients in Korea has not been defined yet. In this study, we investigated the frequency of FEG and other gastric histological abnormalities in Korean patients with CD and UC.
  
  
  METHODS
  We evaluated 37 patients with known CD, 43 patients with UC and 41 non-IBD control group; all underwent upper gastrointestinal endoscopy followed by biopsy from the antrum and the body. The pathology of the gastric biopsy specimens and the presence of Helicobacter pylori (H. pylori) were evaluated. FEG was characterized by a focal perifoveolar or periglandular inflammatory cell infiltrates.
  
  
  RESULTS
  H. pylori positive gastritis was found in 10 of 37 (27.0%) of CD patients, in 16 of 43 (37.2%) of UC patients, and in 22 of 41 (53.7%) of non-IBD control group (p=0.054). In H. pylori-negative patients, FEG was found in 8 of 27 patients (29.6%) of CD patients, 6 of 27 (22.2%) patients with UC, and 2 of 9 (10.5%) of non-IBD control group (p=0.324).
  
  
  CONCLUSIONS
  In H. pylori-negative patients, there was no statistically significant difference in the occurrence of FEG among CD, UC and control groups in Korea.
authors.affiliation: Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Cheul Ho
authors.initials: CH
authors.lastname: Hong
authors.forename: Dong Il
authors.initials: DI
authors.lastname: Park
authors.forename: Woo Hyuk
authors.initials: WH
authors.lastname: Choi
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Park
authors.forename: Hong Joo
authors.initials: HJ
authors.lastname: Kim
authors.forename: Yong Kyun
authors.initials: YK
authors.lastname: Cho
authors.forename: Chong Il
authors.initials: CI
authors.lastname: Sohn
authors.forename: Woo Kyu
authors.initials: WK
authors.lastname: Jeon
authors.forename: Byung Ik
authors.initials: BI
authors.lastname: Kim
authors.forename: Dong Hoon
authors.initials: DH
authors.lastname: Kim
authors.forename: Min Kyung
authors.initials: MK
authors.lastname: Kim
authors.forename: Seung Wan
authors.initials: SW
authors.lastname: Chae
authors.forename: Kyoung Bun
authors.initials: KB
authors.lastname: Lee
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Sohn
authors.forename: Suk Joong
authors.initials: SJ
authors.lastname: Oh
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003424:Crohn Disease / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005260:Female; D005756:Gastritis / Q000453:epidemiology / Q000473:pathology*; D005773:Gastroscopy; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D041742:Upper Gastrointestinal Tract / Q000473:pathology