[Analysis on the risk factors of maternal weight for fetal macrosomia].
OBJECTIVE
To investigate the relationship between maternal weight gain and the increasing speed of weight in different pregnant terms and macrosomia. In order to reasonably manage pregnancy and decrease the morbidity of macrosomia.


METHODS
106 newborns whose birth weights were equal to or greater than 4000 g were specified as macrosomia, while 106 newborn with birth weights lying in 2500 - 3999 g were under the control group. A case-control study was conducted to compare the corresponding factors such as maternal BMI, weight before pregnancy and the change of weight during pregnancy respectively.


RESULTS
Indicated by both simple and multiple unconditional logistic regression analysis, the cause of fetal macrosomia was mainly associated with the factors including the maternal weight before pregnancy (OR = 2.204, 95%CI: 1.377 - 3.529), maternal weight gain in 12-pregnant weeks (kg per week) (OR = 1.961, 95%CI: 1.204 - 3.194), maternal weight gain in 20-gestation weeks (kg per week) (OR = 1.811, 95%CI: 1.078 - 3.041), maternal weight gain in 30-pregnant weeks (kg per week) (OR = 1.858, 95%CI: 1.095 - 3.153) and virile newborn (OR = 2.630, 95%CI: 1.420 - 4.850. When in 30-pregnant weeks, the pregnant women with 0.5 - 1.0 kg weight gain per week had 1.13 fold risks comparing to those whose weight gains were less than 0.5 kg per week.


CONCLUSIONS
Maternal weight before pregnancy, weight gain during pregnancy and fetal sex appeared a closer relation to macrosomia. It is necessary to monitor the change of maternal weight during different pregnancy periods, especially for the 30th-pregnant weeks.
Jiang
Hua
H
Changzhou Women and Children Health Hospital, Changzhou 213003, China.
Cai
Yun-qing
YQ
Qian
Qiu-ying
QY
Xun
Peng-cheng
PC
Wang
Qiu-wei
QW
D001724:Birth Weight; D001835:Body Weight; D016022:Case-Control Studies; D005260:Female; D005320:Fetal Macrosomia / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D012307:Risk Factors; D012737:Sex Factors