Nickel-catalyzed [4 + 2] cycloaddition of enones with alkynes.
A nickel-catalyzed [4 + 2] cycloaddition reaction has been developed where enones react with alkynes to afford polysubstituted pyrans. A mechanistic rationale is proposed, implying oxa-nickela cycle formation by oxidative cyclization of nickel to enone, followed by alkyne insertion.
Koyama
Ichiro
I
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Kurahashi
Takuya
T
Matsubara
Seijiro
S
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000737:chemistry*
D000480:Alkynes; D011083:Polycyclic Compounds; D009532:Nickel