Successful pregnancy after treatment for ovarian malignant teratoma with growing teratoma syndrome.
OBJECTIVE
To report a case of successful IVF-pregnancy after treatment for ovarian growing teratoma syndrome.


METHODS
Case report.


METHODS
Gynecologic department at a university hospital.


METHODS
A 20-year-old woman, gravida 0 para 0, was diagnosed with malignant teratoma of the ovary. She was treated by unilateral salpingo-oophorectomy and chemotherapy. A couple of years later she was diagnosed with growing teratoma syndrome.


METHODS
Fertility-preserving surgery with unilateral salpingo-oophorectomy and chemotherapy. In vitro fertilization.


METHODS
Disease free, successful pregnancy.


RESULTS
After treatment for ovarian immature teratoma and growing teratoma syndrome the patient was free of the disease. She underwent in vitro fertilization treatment with autologous embryo transfer and gave birth to a healthy child.


CONCLUSIONS
Growing teratoma syndrome is an extremely rare metastatic complication of a malignant germ cell tumor after a combination treatment with surgery and adjuvant chemotherapy. This case shows that successful pregnancy outcome is possible after effective treatment for ovarian growing teratoma syndrome.
Tzortzatos
Gerasimos
G
Department of Obstetrics and Gynecology, Karolinska University Hospital/Karolinska Institute, Stockholm, Sweden. gerasimos.tzortzatos@karolinska.se
Sioutas
Angelos
A
Schedvins
Kjell
K
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D017024:Chemotherapy, Adjuvant; D004624:Embryo Transfer; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D050498:Live Birth; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000473:pathology / Q000628:therapy*; D010052:Ovariectomy / Q000009:adverse effects*; D011247:Pregnancy; D013577:Syndrome; D013724:Teratoma / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult