title: Topiramate-associated acute glaucoma in a migraine patient receiving concomitant citalopram therapy: a case-report.
abstract: We describe the case of a 34 year-old man with diagnosis of migraine with and without aura that developed myopia and acute glaucoma after 7 days of treatment with topiramate. The patient had also been taking citalopram daily for two months. Both topiramate and citalopram have been related to the increase of intraocular pressure and the development of glaucoma. We can't exclude that in this patient citalopram caused an increase of the ocular pressure in dose-dependent manner, facilitating topiramate-induced glaucoma. We recommend to pay particular attention in prescribing of topiramate in migraine patients who are already under treatment with citalopram or other antidepressants with a similar mechanisms of action.
authors.affiliation: Headache Centre, Division of Toxicology and Clinical Pharmacology, University of Modena and Reggio Emilia, Modena, Italy. lukespacca@hotmail.com.
authors.forename: Luca
authors.initials: L
authors.lastname: Spaccapelo
authors.forename: Silvia
authors.initials: S
authors.lastname: Leschiutta
authors.forename: Claudio
authors.initials: C
authors.lastname: Aurea
authors.forename: Anna
authors.initials: A
authors.lastname: Ferrari