Sesquiterpenoids and phenylpropanoids from pericarps of Illicium oligandrum.
Four new merrillianin-type sesquiterpenes, oligandrumins A-D (1-4), two new seco-prezizaane-type sesquiterpenes, veranisatins D and E (5 and 6), and a new phenylpropane glycoside, oligandrumin E (7), were isolated from the ethanol extract of pericarps of Illicium oligandrum, together with six known sesquiterpenoids and two phenylpropanoids. Their structures were established on the basis of extensive spectroscopic analyses. The structures of 1 and 2 were further confirmed by single-crystal X-ray diffraction experiments. Anislactone B (13) and the erythro form of anethole glycol (14) were shown to attenuate the damage induced by H(2)O(2) in SH-SY5Y cells.
Zhu
Qin
Q
State Key Laboratory of Drug Research & Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
Tang
Chun-Ping
CP
Ke
Chang-Qiang
CQ
Wang
Wei
W
Zhang
Hai-Yan
HY
Ye
Yang
Y
D018360:Crystallography, X-Ray; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006861:Hydrogen Peroxide / Q000633:toxicity*; D029523:Illicium / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010666:Phenylpropionates; D012717:Sesquiterpenes; C550394:oligandrumin E; D006861:Hydrogen Peroxide