title: Two-dimensional strain and strain rate imaging of the right ventricle in adult patients before and after percutaneous closure of atrial septal defects.
abstract: OBJECTIVE
  Echocardiographic speckle tracking or two-dimensional (2D) strain analysis is a new tool to assess myocardial function. This prospective controlled study evaluates systolic right ventricular (RV) function by 2D strain in adult patients with atrial septal defect (ASD) before and 3 months after percutaneous closure.
  
  
  RESULTS
  Assessment of global longitudinal strain (GLS), global longitudinal strain rate (GLSR), and regional peak systolic strain (PSS) of right ventricle was performed in 33 ASD patients. The data were compared with those from 34 age-matched adults with patent foramen ovale. Before percutaneous closure, mean GLS was significantly increased in comparison to control group, and significantly reduced after closure. Analysis of regional PSS showed significant decrease in the lateral apical, lateral mid, and septal apical segments. GLSR was not influenced by ASD closure.
  
  
  CONCLUSIONS
  Two-dimensional strain appears to be helpful also for the assessment of RV function and its response to correction of volume overload.
authors.affiliation: Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
authors.forename: Smita R
authors.initials: SR
authors.lastname: Jategaonkar
authors.forename: Werner
authors.initials: W
authors.lastname: Scholtz
authors.forename: Thomas
authors.initials: T
authors.lastname: Butz
authors.forename: Nikola
authors.initials: N
authors.lastname: Bogunovic
authors.forename: Lothar
authors.initials: L
authors.lastname: Faber
authors.forename: Dieter
authors.initials: D
authors.lastname: Horstkotte
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002306:Cardiac Volume; D016022:Case-Control Studies; D004452:Echocardiography; D018618:Echocardiography, Doppler, Color; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000000981:diagnostic imaging; D016278:Ventricular Function, Right / Q000502:physiology*