title: A fatal case of cerebral oedema with hyponatraemia and massive polyuria after renal transplantation.
abstract: We report the case of a child who died from severe cerebral oedema in the context of hyponatraemia and extreme polyuria immediately after renal transplantation. The patient was treated according to a standard post-transplantation protocol, receiving 0.45% saline solution for urine output replacement. The case highlights the dangers of massive fluid therapy in the context of polyuria and, therefore, the need for intensive monitoring.
authors.affiliation: Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK.
authors.forename: Janette
authors.initials: J
authors.lastname: Cansick
authors.forename: Lesley
authors.initials: L
authors.lastname: Rees
authors.forename: Geoff
authors.initials: G
authors.lastname: Koffman
authors.forename: William
authors.initials: W
authors.lastname: Van't Hoff
authors.forename: Detlef
authors.initials: D
authors.lastname: Bockenhauer
mesh_terms: D001929:Brain Edema / Q000601:surgery*; D002648:Child; D017809:Fatal Outcome; D005440:Fluid Therapy; D006801:Humans; D007010:Hyponatremia / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D011141:Polyuria / Q000188:drug therapy / Q000601:surgery*