title: A clinical evaluation of non-invasive motor imagery-based brain-computer interface in stroke.
abstract: This clinical study investigates whether the performance of hemiparetic stroke patients operating a non-invasive Motor Imagery-based Brain-Computer Interface (MI-BCI) is comparable to healthy subjects. The study is performed on 8 healthy subjects and 35 BCI-naïve hemiparetic stroke patients. This study also investigates whether the performance of the stroke patients in operating MI-BCI correlates with the extent of neurological disability. The performance is objectively computed from the 10 x 10-fold cross-validation accuracy of employing the Filter Bank Common Spatial Pattern (FBCSP) algorithm on their EEG measurements. The neurological disability is subjectively estimated using the Fugl-Meyer Assessment (FMA) of the upper extremity. The results show that the performance of BCI-naïve hemiparetic stroke patients is comparable to healthy subjects, and no correlation is found between the accuracy of their performance and their motor impairment in terms of FMA.
authors.affiliation: Institute for Infocomm Research, Agency for Science, Technology and Research (ASTAR), 21 Heng Mui Keng Terrace, Singapore 119613. kkang@i2r.astar.edu.sg
authors.forename: Kai Keng
authors.initials: KK
authors.lastname: Ang
authors.forename: Cuntai
authors.initials: C
authors.lastname: Guan
authors.forename: Karen Sui Geok
authors.initials: KS
authors.lastname: Chua
authors.forename: Beng Ti
authors.initials: BT
authors.lastname: Ang
authors.forename: Christopher Wee Keong
authors.initials: CW
authors.lastname: Kuah
authors.forename: Chuanchu
authors.initials: C
authors.lastname: Wang
authors.forename: Kok Soon
authors.initials: KS
authors.lastname: Phua
authors.forename: Zheng Yang
authors.initials: ZY
authors.lastname: Chin
authors.forename: Haihong
authors.initials: H
authors.lastname: Zhang
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D001921:Brain / Q000502:physiology*; D016022:Case-Control Studies; D005071:Evoked Potentials / Q000502:physiology; D006801:Humans; D007092:Imagination / Q000502:physiology; D009068:Movement / Q000502:physiology*; D009422:Nervous System Diseases / Q000534:rehabilitation; D010291:Paresis / Q000534:rehabilitation; D015203:Reproducibility of Results; D000071939:Stroke Rehabilitation; D014584:User-Computer Interface