Evaluation of cortical visual prostheses microelectrode array function. Description of behavioral feline model.
Felines are highly organized mammals with relatively similar to human structure-functional visual system and they are able to create reflex behavior in response to specific stimulus. Thus, feline model seems to be valuable in checking microelectrode array function in visual prosthetic device before experimenting in human. We believe that reflex behavior developed by cats in our experiment of response to electric stimulus delivered from microelectrode array is a response to phosphenes, similar to light stimulus response.
Ivanova
Marianna E
ME
Science Center of Neurology, Brain Research Dept., Russian Academy of Science, Moscow, Russia. nonhores@gmail.com
Gordeev
Sergey A
SA
Ortmann
Valerij V
VV
Baziyan
Boris Kh
BKh
D000818:Animals; D001522:Behavior, Animal; D001931:Brain Mapping; D002415:Cats; D004558:Electric Stimulation / Q000379:methods*; D004566:Electrodes; D004567:Electrodes, Implanted; D008027:Light; D008839:Microelectrodes; D010465:Perception; D010719:Phosphenes; D012160:Retina / Q000473:pathology; D013997:Time Factors; D014785:Vision, Ocular; D014793:Visual Cortex / Q000502:physiology*