Diffusion of macromolecules in model oral biofilms.
The diffusive penetration of fluorescently tagged macromolecular solutes into model oral biofilms was visualized by time-lapse microscopy. All of the solutes tested, including dextrans, proteases, green fluorescent protein, and immunoglobulin G, accessed the interior of cell clusters 100 to 200 microm in diameter within 3 min or less.
Takenaka
Shoji
S
Division of Cariology, Niigata University, Niigata, Japan.
Pitts
Betsey
B
Trivedi
Harsh M
HM
Stewart
Philip S
PS
D018441:Biofilms; D004058:Diffusion; D005453:Fluorescence; D046911:Macromolecular Substances / Q000378:metabolism*; D018715:Microscopy, Video
D046911:Macromolecular Substances