[A dynamic analysis on incidence and trend of HIV-1 epidemics among intravenous drug users, attendants at the STD clinics and pregnant women in Yunnan province, China].
OBJECTIVE
BED-CEIA assay was used in HIV/AIDS surveillance sentinel sites to identify recent HIV-1 infection, to estimate HIV-1 incidence and to understand the epidemic trends in Yunnan province.


METHODS
Serum specimens were collected from IDUs in sentinel sites, attendants in STD clinics and pregnant women under a cross sectional study from 2000 to 2007. Specimens confirmed as HIV-1 positive were tested with BED-CEIA to find recent HIV-1 infection, then the annual HIV-1 incidence for each group was calculated and the trends of HIV-1 incidence observed.


RESULTS
144 780 serum specimens were collected and 4932 of them were confirmed as HIV-1 positive. 4678 positive specimens were tested with BED-CEIA and 723 ont of them were identified as recent infections. Specimens from the two years were combined for testing. The average HIV-1 prevalence among IDUs was 18.2% - 26.9% from 2000 to 2007 and the annual incidence were 14.65%, 6.21%, 4.06%, 2.23% respectively. The average HIV-1 prevalence among attendants in STD clinics was 1.6% - 3.2% and the annual incidence rates were 1.46%, 0.76%, 0.52%, 0.33% respectively. The average HIV-1 prevalence among pregnant women was 0.2% - 0.5% and the annual incidence rates were 0.16%, 0.11%, 0.10%, 0.09% respectively.


CONCLUSIONS
HIV-1 incidence rates among IDUs, STDs and pregnant women showed a steady decrease.
Yang
Li
L
Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
Ma
Yan-ling
YL
Luo
Hong-bing
HB
Jia
Man-hong
MH
Yang
Chao-jun
CJ
Wang
Min-jie
MJ
Chen
Hui-chao
HC
Shen
Sheng
S
Mei
Jing-yuan
JY
Tian
Fei
F
Shi
Yu-hua
YH
Yan
Wen-yun
WY
Lu
Lin
L
Jiang
Yan
Y
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D015995:Prevalence; D018571:Sentinel Surveillance; D012749:Sexually Transmitted Diseases / Q000453:epidemiology*; D015819:Substance Abuse, Intravenous / Q000453:epidemiology*