Neurotoxicity with therapeutic lithium levels: a case report.
This case report describes the history and hospital course of an otherwise healthy 20-year-old male with bipolar I disorder who developed symptoms of severe lithium toxicity, culminating in a seizure, despite a level of lithium of only 0.8 mEq/L, within the usual therapeutic range. The discussion emphasizes that lithium toxicity is diagnosed by clinical symptoms and can occur even at usual therapeutic blood levels.
Grueneberger
Elizabeth C
EC
Columbia University Department of Psychiatry, USA.
Maria Rountree
E
E
Baron Short
E
E
Kahn
David A
DA
D018692:Antimanic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics; D001569:Benzodiazepines / Q000008:administration & dosage / Q000493:pharmacokinetics; D001714:Bipolar Disorder / Q000188:drug therapy*; D062787:Drug Overdose; D006801:Humans; D016651:Lithium Carbonate / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D000077152:Olanzapine; D012640:Seizures / Q000139:chemically induced*; D013406:Suicide, Attempted; D055815:Young Adult
D018692:Antimanic Agents; D014150:Antipsychotic Agents; D001569:Benzodiazepines; D016651:Lithium Carbonate; D000077152:Olanzapine