title: Ictal vomiting as an initial symptom of severe myoclonic epilepsy in infancy: a case report.
abstract: We report on 3-year-old Japanese twin brothers suffering from ictal vomiting during infancy. Intractable seizures, including generalized tonic-clonic convulsions, and myoclonic seizures persisted in late infancy. The diagnosis of severe myoclonic epilepsy in infancy was confirmed by detecting a mutation in the voltage-gated sodium channel alpha subunit type gene. This is the first case report addressing ictal vomiting as the initial presentation of severe myoclonic epilepsy in infancy.
authors.affiliation: Department of Pediatrics, Tohoku University School of Medicine, Aoba-ku, Sendai, Japan.
authors.forename: Naomi
authors.initials: N
authors.lastname: Hino-Fukuyo
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Haginoya
authors.forename: Noriko
authors.initials: N
authors.lastname: Togashi
authors.forename: Mitsugu
authors.initials: M
authors.lastname: Uematsu
authors.forename: Taro
authors.initials: T
authors.lastname: Kitamura
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kakisaka
authors.forename: Mamiko
authors.initials: M
authors.lastname: Ishitobi
authors.forename: Keisuke
authors.initials: K
authors.lastname: Wakusawa
authors.forename: Kazuie
authors.initials: K
authors.lastname: Iinuma
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Oguni
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yamakawa
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tsuchiya
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D004200:Diseases in Twins / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D004831:Epilepsies, Myoclonic / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008297:Male; D009154:Mutation; D012640:Seizures; D015222:Sodium Channels / Q000235:genetics; D014839:Vomiting / Q000209:etiology*
chemical_list: D015222:Sodium Channels