title: The development of a MIP-optosensor for the detection of monoamine naphthalenes in drinking water.
abstract: To enhance the advantages of fluorescent flow-through sensing for drinking water we have designed a novel sensing matrix based on molecularly imprinted polymers (MIPs). The synergic combination of a tailor-made MIP recognition with a selective room temperature fluorescence detection is a novel concept for optosensing devices and is assessed here for the simple and selective determination of pollutants in water. We describe a simple approach to preparing synthetic receptors for monoamine naphthalene compounds (MA-NCs) using non-covalent molecular imprinting techniques and naphthalene as template. We examine in detail the binding characteristics of the imprinted polymer and describe the flow-through sensor of MA-NCs by solid-surface fluorescence. Its detection limits for recognizing 1-naphthylamine (1-NA) and 2-naphthylamine (2-NA) separately are 26 ngmL(-1) and 50 ngmL(-1), respectively, and it also determines 1-NA and 2-NA simultaneously with a detection limit of 45 ngmL(-1). All the instrumental, chemical and flow variables were carefully optimized and an interference study was carried out to demonstrate its applicability and selectivity. Finally, we applied it to the analysis of 1-NA and 2-NA in tap and mineral waters, obtaining a 98% average recovery rate.
authors.affiliation: Department of Analytical Chemistry, University of Granada, c/Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: Angel
authors.initials: A
authors.lastname: Valero-Navarro
authors.forename: Alfonso
authors.initials: A
authors.lastname: Salinas-Castillo
authors.forename: Jorge F
authors.initials: JF
authors.lastname: Fernández-Sánchez
authors.forename: Antonio
authors.initials: A
authors.lastname: Segura-Carretero
authors.forename: Ricardo
authors.initials: R
authors.lastname: Mallavia
authors.forename: Alberto
authors.initials: A
authors.lastname: Fernández-Gutiérrez
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D017076:Computer-Aided Design; D004784:Environmental Monitoring / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D017022:Flow Injection Analysis / Q000295:instrumentation*; D009281:Naphthalenes / Q000032:analysis*; D055096:Optical Devices; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis*
chemical_list: D009281:Naphthalenes; D014874:Water Pollutants, Chemical