Mechanochemical solvent-free and catalyst-free one-pot synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones with quantitative yields.
Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.
Mashkouri
Sara
S
Organic Chemistry Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846 Tehran, Iran.
Naimi-Jamal
M Reza
MR
D000447:Aldehydes / Q000737:chemistry; D001463:Barbiturates / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents
D000447:Aldehydes; D001463:Barbiturates; D009570:Nitriles; D011743:Pyrimidines; D012997:Solvents; C000945:dicyanmethane; C032232:barbituric acid