[Necrosis of the tongue triggered by ergotamine in unrecognized temporal arteritis].
Tongue necrosis is a rare complication in arteritis temporalis. Our case is a 74-year-old patient who presented with weight loss, tiredness and fever during a 2-3-month period after ingestion of 2 mg ergotamine to treat her migraine. Tongue necrosis then occurred after ingestion of another 2 mg of ergotamine. Our patient had no preexisting diagnosis of arteritis temporalis. We reviewed possible clinical manifestations of temporal arteritis and cases of tongue necrosis in the world literature. It is possible that ergotamine can cause necrosis due to vasoconstriction of blood vessels which have an unstable blood flow.
Olesen
Jesper Blegvad
JB
Regionshospitalet Horsens, Medicinsk Afdeling. Jesper.blegvad@ki.au.dk
D000368:Aged; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy; D009336:Necrosis; D014059:Tongue / Q000187:drug effects / Q000473:pathology*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000009:adverse effects*
D014662:Vasoconstrictor Agents; D004878:Ergotamine