title: [Non-chlamydial non-gonococcal urethritis].
abstract: Besides Chlamydia trachomatis, various microorganisms could cause non-gonococcal urethritis (NGU). Recently, Mycoplasma genitalium and Ureaplasma urealyticum (biovar 2) have been suggested to be other pathogens of NGU independent of C. trachomatis. Clinical findings of non-chlamydial NGU, including M. genitalium--or U. urealyticum-postive NGU, are not different from those of chlamydial NGU. M. genitalium and U. urealyticum (biovar 2) are susceptible to tetracyclines, macrolides, and fluoroquinolones. However, the post-treatment presence of M. genitalium in the urethra is significantly associated with persistent or recurrent urethritis. Eradication of this mycoplasma from the urethra is essential for managing M. genitalium-positive NGU. In treatment of non-chlamydial NGU, therefore, the antimicrobial agents that are active against M. genitalium should be chosen.
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University.
authors.forename: Takashi
authors.initials: T
authors.lastname: Deguchi
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Yasuda
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Maeda
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D024841:Fluoroquinolones / Q000008:administration & dosage; D006801:Humans; D018942:Macrolides / Q000008:administration & dosage; D008297:Male; D009175:Mycoplasma Infections; D045704:Mycoplasma genitalium; D015231:Sexually Transmitted Diseases, Bacterial; D013754:Tetracyclines / Q000008:administration & dosage; D016869:Ureaplasma Infections; D016990:Ureaplasma urealyticum; D014526:Urethritis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology* / Q000503:physiopathology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D018942:Macrolides; D013754:Tetracyclines