title: Retention and protocol adherence of Hispanic volunteers in a longitudinal trial.
abstract: OBJECTIVE
  To compare Hispanic research volunteers with high and low levels of study retention and adherence.
  
  
  METHODS
  Correlational analysis of demographics, recruitment strategies, knowledge, and attitudes of 470 households in a clinical trial.
  
  
  RESULTS
  Within 12 months, 53 (11.3%) households dropped out; those less certain about some factual information were more likely to drop out (P < 0.05). Participants born outside the United States were more likely to adhere to protocols (P = 0.03). Flyers were effective for recruiting only 3% of participants.
  
  
  CONCLUSIONS
  In newly immigrated populations, written recruitment materials may be ineffective; knowledge and attitudes may be important for study retention and adherence.
authors.affiliation: School of Nursing, Columbia University, New York, NY 10032, USA. ELL23@columbia.edu
authors.forename: Elaine L
authors.initials: EL
authors.lastname: Larson
authors.forename: Yu-Hui
authors.initials: YH
authors.lastname: Ferng
authors.forename: Jennifer
authors.initials: J
authors.lastname: Wong-McLoughlin
authors.forename: Shuang
authors.initials: S
authors.lastname: Wang
mesh_terms: D000328:Adult; D019983:Guideline Adherence; D006630:Hispanic or Latino; D006805:Human Experimentation; D006801:Humans; D008137:Longitudinal Studies; D009519:New York City; D010558:Personnel Loyalty; D012106:Research