The PTP family photo album.
Protein tyrosine phosphatases (PTPs) are central players in many biological processes. In this issue, Barr et al. (2009) analyze 22 different PTP structures to define their common and unique features. This effort provides key insights into the regulation of PTP activity that could lead to the development of new therapeutics.
Tremblay
Michel L
ML
Goodman Cancer Centre, Biochemistry Department, Montreal, Quebec H3G 0B1, Canada. michel.tremblay@mcgill.ca
D006801:Humans; D017027:Protein Tyrosine Phosphatases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D020543:Proteome; D013329:Structure-Activity Relationship
D020543:Proteome; D017027:Protein Tyrosine Phosphatases