title: Hypertrophic osteoarthropathy masquerading as lower extremity cellulitis and response to bisphosphonates.
abstract: Hypertrophic osteoarthropathy (HOA) is characterized by clubbing of digits and, in more advanced stages, by periosteal new bone formation and synovial effusions. Secondary HOA typically occurs in the setting of intrathoracic malignancy, infections or lung metastases. We report a case with an atypical presentation of HOA. The prominent systemic signs, presentation limited to lower extremities only and an excellent response to bisphosphonates make this case unusual.
authors.affiliation: Department of Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
authors.forename: Obondent
authors.initials: O
authors.lastname: Mauricio
authors.forename: Lisa
authors.initials: L
authors.lastname: Francis
authors.forename: Uzma
authors.initials: U
authors.lastname: Athar
authors.forename: Chirag
authors.initials: C
authors.lastname: Shah
authors.forename: Madhuchhanda
authors.initials: M
authors.lastname: Chaudhary
authors.forename: Ajeet
authors.initials: A
authors.lastname: Gajra
mesh_terms: D000328:Adult; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002481:Cellulitis / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000627:therapeutic use*; D006801:Humans; D035002:Lower Extremity; D008297:Male; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates