title: Radiation effects in interventional radiology using biological and physical dosimetry methods: a case-control study.
abstract: Interventional radiologists and staff members are frequently exposed to protracted and fractionated low doses of ionizing radiation, which extend during all their professional activities. These exposures can derive, due to the irradiation of skin tissues and peripheral blood, in deterministic effects (radiodermitis, aged skin, hands depilation) or stochastic ones (skin and non-solid cancers incidence). Epidemiological studies of population exposed to ionizing radiation provide information of radio-induced effects. The radiation risk or radiological detriment has been estimated from a group of six exposed interventionist radiologists of the Hospital La Fe (Valencia, Spain). Dosimetry has been periodically registered from TLDs and wrist dosimeters (physical methods) and estimated through translocations in lymphocytes of peripheral blood (biological methods), by extrapolating the yield of translocations to their respective dose-effect curves. The probability of non-melanoma skin cancer and leukaemia (acute myelogenous, acute lymphocytic and chronic myelogenous leukaemia) incidence has been estimated through the software RADRISK. This software is based on a transport model from epidemiological studies of population exposed to external low-LET ionizing radiation [1]. Other non-solid carcinomas have not been considered due to their low statistical power, such as myeloid and non-Hodgkin lymphomas. The discrepancies observed between the physically recorded doses and biological estimated doses could indicate that exposed workers did not always wear their dosimeters or these dosimeters were not always exposed to the radiation field.
authors.affiliation: Departamento de Ingeniería Química y Nuclear, Universidad Politécnica de Valencia, Spain. mirapas@iqn.upv.es
authors.forename: Miguel
authors.initials: M
authors.lastname: Ramos
authors.forename: Alegria
authors.initials: A
authors.lastname: Montoro
authors.forename: Miguel
authors.initials: M
authors.lastname: Almonacid
authors.forename: Silvia
authors.initials: S
authors.lastname: Ferrer
authors.forename: Joan Francesc
authors.initials: JF
authors.lastname: Barquinero
authors.forename: Ricardo
authors.initials: R
authors.lastname: Tortosa
authors.forename: Gumersindo
authors.initials: G
authors.lastname: Verdú
authors.forename: Pilar
authors.initials: P
authors.lastname: Rodríguez
authors.forename: Lleonard
authors.initials: L
authors.lastname: Barrios
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: Villaescusa
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000453:epidemiology; D016273:Occupational Exposure; D015642:Radiology, Interventional / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D012306:Risk; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012984:Software