What is known to us about renal function of our retired peoples?
BACKGROUND
Bangladesh is one of the twenty countries in the world with the largest elderly populations, and by 2025, along with four other Asian countries, will account for 44% of world's total elderly population. This rapidly increasing population is a new and important group in terms of social and health policy in the country. As retired geriatric population is increasing day by day and there is a striking increase in their life expectancy and a decrease kidney function recognized as risk factor for morbidity and mortality in the elderly so evaluation of the renal function of retired persons are essential.


OBJECTIVE
To assess the renal function of retired geriatric population by estimation of creatinine clearance by Cockcroft-Gault formula.


METHODS
This was a cross-sectional study.


METHODS
Retired persons aged 57 years and above without known hypertension, diabetes, renal diseases as study group and healthy adult aged 18-55 years as control group were included in this study. All were obtained from different areas of greater Mymensingh districts.


METHODS
Under strict aseptic precaution, venous blood was collected and serum creatinine of all were measured by deproteinization method and then calculation of creatinine clearance was done by using Cock-croft Gault formula.


METHODS
Serum Creatinine, Creatinine clearance.


RESULTS
Significant decrease of creatinine clearance was found in the study group (57 years and above) in comparison to control group (p<0.001). There is progressive decrease of creatinine clearance values by age.


CONCLUSIONS
Calculation of Creatinine clearance by Cock-croft formula is not unambiguous and still not accepted unanimously globally. The other tests of renal function were not done.


CONCLUSIONS
Though the mean creatinine clearance values were significantly decreased in 57 years and above which was progressively decreased by age, yet values were within normal physiological limits. So the retired geriatric population has good renal function in our setting.
Khan
H U
HU
Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh. hafiz2008bd@yahoo.com
Latif
S A
SA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001459:Bangladesh / Q000453:epidemiology; D016022:Case-Control Studies; D003404:Creatinine / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D007668:Kidney / Q000502:physiology* / Q000503:physiopathology; D007674:Kidney Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D012179:Retirement; D055815:Young Adult
D003404:Creatinine