Systemic sclerosis associated with rectal cancer. Case report and a brief review of the literature.
Autoimmune diseases may appear as paraneoplastic syndromes during the course of a neoplastic disease, the most common being dermatomyositis/ polymyositis. The association of systemic sclerosis and cancer is not clear. The case of a 56-year-old male with rectal cancer and systemic sclerosis where the coexistence of the two diseases was closely related, so that scleroderma was considered a paraneoplastic syndrome rather than a concomitant morbid condition, is presented.
Orphanos
George
G
First Department of Medical Oncology, Ag. Savvas Anticancer Hospital, Athens, Greece. georgeorphanosvp@hotmail.com
Ardavanis
Alexandros
A
Charalambous
Paraskevi
P
Stavrakakis
John
J
Rigatos
Gerassimos
G
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001706:Biopsy; D003082:Colectomy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications / Q000473:pathology; D012004:Rectal Neoplasms / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D012595:Scleroderma, Systemic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D000305:Adrenal Cortex Hormones; D008775:Methylprednisolone