title: Preparation of porous 45S5 Bioglass-derived glass-ceramic scaffolds by using rice husk as a porogen additive.
abstract: Bioactive glass is currently regarded as the most biocompatible material in the bone regeneration field because of its bioactivity, osteoconductivity and even osteoinductivity. In the present work porous glass-ceramic scaffolds, which were prepared from the 45S5 Bioglass by foaming with rice husks and sintering at 1050 degrees C for 1 h, have been developed. The produced scaffolds were characterized for their morphology, properties and bioactivity. Micrographs taken using a scanning electron microscope (SEM) were used for analysis of macropores, mesopores and micropores, respectively. The bioactivity of the porous glass-ceramic scaffolds was investigated using simulated body fluid (SBF) and characterized by SEM, energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD). A great potential scaffold that provides sufficient mechanical support temporarily while maintaining bioactivity, and that can biodegrade at later stages is achievable with the developed 45S5 Bioglass-derived scaffolds.
authors.affiliation: Department of Dental Laboratory Technology, Central Taiwan University of Science and Technology, Taichung, ROC.
authors.forename: Shih-Ching
authors.initials: SC
authors.lastname: Wu
authors.forename: Hsueh-Chuan
authors.initials: HC
authors.lastname: Hsu
authors.forename: Sheng-Hung
authors.initials: SH
authors.lastname: Hsiao
authors.forename: Wen-Fu
authors.initials: WF
authors.lastname: Ho
mesh_terms: D001672:Biocompatible Materials / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D001696:Biomechanical Phenomena; D001826:Body Fluids / Q000737:chemistry / Q000378:metabolism; D018786:Bone Substitutes / Q000378:metabolism; D002516:Ceramics / Q000737:chemistry*; D004577:Electron Probe Microanalysis; D005898:Glass / Q000737:chemistry*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D012275:Oryza / Q000378:metabolism*; D016062:Porosity; D013499:Surface Properties; D013696:Temperature; D013997:Time Factors; D023822:Tissue Engineering / Q000379:methods; D054457:Tissue Scaffolds; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; C425330:bioactive glass 45S5