title: The influence of combined exercise training on indices of obesity, physical fitness and lipid profile in overweight and obese adolescents with mental retardation.
abstract: BACKGROUND
  This study investigated the effect of combined exercise training on indices of body composition, physical fitness and lipid profile in adolescents with mental retardation.
  
  
  METHODS
  Thirty adolescents with mental retardation (total IQ, 45-70) received exercise training (n = 15) or no training (n = 15). Groups were matched for age, sex and mental retardation. Before and after the intervention period, indices of body composition, physical fitness and lipid profile were measured.
  
  
  RESULTS
  In comparison with the control group, weight, body mass index, waist and fat mass decreased significantly, while relative fat-free mass increased. The level of triglycerides, total cholesterol and low-density lipoprotein decreased significantly, while high-density lipoprotein increased. Muscle strength, muscle fatigue resistance and sit-to-stand were ameliorated. PeakVO2/peak power decreased significantly. The distance covered in the 6-min walk test (6MWT) increased with 50 m.
  
  
  CONCLUSIONS
  In conclusion, combined exercise training has a positive effect on indices of obesity, physical fitness and lipid profile in adolescents with mental retardation.
authors.affiliation: Rehabilitation Sciences and Physiotherapy Ghent Campus Heymans 1B3, University of Ghent, De Pintelaan 185, 9000 Ghent, Belgium.
authors.forename: Sami Mohammed
authors.initials: SM
authors.lastname: Elmahgoub
authors.forename: Sabine
authors.initials: S
authors.lastname: Lambers
authors.forename: Sanne
authors.initials: S
authors.lastname: Stegen
authors.forename: Christophe
authors.initials: C
authors.lastname: Van Laethem
authors.forename: Dirk
authors.initials: D
authors.lastname: Cambier
authors.forename: Patrick
authors.initials: P
authors.lastname: Calders
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D015444:Exercise; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000097:blood* / Q000150:complications / Q000534:rehabilitation; D008074:Lipoproteins / Q000097:blood; D008297:Male; D009765:Obesity / Q000097:blood* / Q000150:complications / Q000534:rehabilitation; D050177:Overweight / Q000097:blood; D010809:Physical Fitness; D011788:Quality of Life; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood*; D049629:Waist-Hip Ratio; D015431:Weight Loss; D055815:Young Adult
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins; D014280:Triglycerides