QMSim: a large-scale genome simulator for livestock.
CONCLUSIONS
QMSim was designed to simulate large-scale genotyping data in multiple and complex livestock pedigrees. The simulation is basically carried out in two steps. In the first step, a historical population is simulated to establish mutation-drift equilibrium, and in the second step, recent population structures are generated, which can be very complex. A wide variety of genome architectures, ranging from infinitesimal model to single-locus model, can be simulated. The program is efficient in terms of computing time and memory requirements.


BACKGROUND
Executable versions of QMSim for Windows and Linux are freely available at http://www.aps.uoguelph.ca/~msargol/qmsim/.
Sargolzaei
Mehdi
M
Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada. msargol@uoguelph.ca
Schenkel
Flavio S
FS
D000818:Animals; D000829:Animals, Domestic / Q000235:genetics*; D019295:Computational Biology / Q000379:methods*; D016678:Genome; D005838:Genotype; D010375:Pedigree; D012984:Software