title: MiRE: a graphical R package for microRNA-related analysis.
abstract: OBJECTIVE
  To provide a set of useful analysis tools for the researchers to explore the microRNA data.
  
  
  METHODS
  The R language was used for generating the Graphical Users Interface and implementing most functions. Some Practical Extraction and Report Language (Perl) scripts were used for parsing source files.
  
  
  RESULTS
  We developed a graphical R package named miRE, which was designated for the analysis of microRNA functions, genomic organization, etc. This package provided effective and convenient tools for molecular biologists to deal with routine analyses in microRNA-related research. With its help, the users would be able to build a desktop-centered microRNA research environment quite easily and effectively. miRE is freely available at http://www. biosino.org/-kanghu/WorkPresentation/miRE/miRE.html. A detailed user manual and tutorials with example code and image are also available.
  
  
  CONCLUSIONS
  miRE is a tool providing an open-source, user-friendly, integrated interface for microRNA-related analysis. With its help, researchers can perform microRNA-related analysis more efficiently.
authors.affiliation: National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005.
authors.forename: Xing-qi
authors.initials: XQ
authors.lastname: Yan
authors.forename: Kang
authors.initials: K
authors.lastname: Tu
authors.forename: Lu
authors.initials: L
authors.lastname: Xie
authors.forename: Yi-xue
authors.initials: YX
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: Yin
authors.forename: Yan-hua
authors.initials: YH
authors.lastname: Gong
authors.forename: Jian-gang
authors.initials: JG
authors.lastname: Yuan
authors.forename: Bo-qin
authors.initials: BQ
authors.lastname: Qiang
authors.forename: Xiao-zhong
authors.initials: XZ
authors.lastname: Peng
mesh_terms: D000465:Algorithms; D035683:MicroRNAs / Q000032:analysis*; D011381:Programming Languages; D017422:Sequence Analysis, DNA; D012984:Software; D014584:User-Computer Interface
chemical_list: D035683:MicroRNAs