Detection of (1-->3)-beta-D-glucan as an adjunct to diagnosis in a mixed population with uncommon proven invasive fungal diseases or with an unusual clinical presentation.
This single-center observational prospective study evaluated the performance of (1-->3)-beta-D-glucan as an adjunct diagnostic tool in 12 patients with proven invasive fungal disease with different risk factors. The infections were due to either uncommon fungal pathogens such as dematiaceous molds (Scedosporium apiospermum, Alternaria infectoria, and Cladosporium macrocarpum) and hyaline septate molds (Fusarium solani and Blastoschizomyces capitatus) or Aspergillus spp. with unusual clinical presentations.
Cuétara
María Soledad
MS
Servicio de Microbiología, Hospital Severo Ochoa, Leganés, Madrid.
Alhambra
Almudena
A
Moragues
María Dolores
MD
González-Elorza
Ernesto
E
Pontón
José
J
del Palacio
Amalia
A
D000368:Aged; D000528:Alternaria / Q000302:isolation & purification; D001230:Aspergillus / Q000302:isolation & purification; D002675:Child, Preschool; D002963:Cladosporium / Q000302:isolation & purification; D055157:Dipodascus / Q000302:isolation & purification; D005260:Female; D005670:Fusarium / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis*; D011446:Prospective Studies; D011509:Proteoglycans; D021681:Scedosporium / Q000302:isolation & purification; D047071:beta-Glucans / Q000097:blood*
D011509:Proteoglycans; D047071:beta-Glucans; C010770:polysaccharide-K