title: Clinical improvement of a patient with severe Wilson's disease after a single session of therapeutic plasma exchange.
abstract: Here, we report a case of a 17-year old female with Wilson's disease presenting with progressive Coombs' negative hemolytic anemia and hepatic cirrhosis who was treated with one session of therapeutic plasma exchange (TPE) and clinically improved. In clinical situations where multiple sessions of TPE may not be possible, the use of a single session of TPE in conjunction with conventional therapy may be of benefit in preventing further clinical deterioration.
authors.affiliation: Internal Medical Department, Vakif Gureba Training and Research Hospital, Istanbul, Turkey. hursitoglum@yahoo.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Hursitoglu
authors.forename: Osman
authors.initials: O
authors.lastname: Kara
authors.forename: Mehmet A
authors.initials: MA
authors.lastname: Cikrikcioglu
authors.forename: Tahsin
authors.initials: T
authors.lastname: Celepkulu
authors.forename: Sengul
authors.initials: S
authors.lastname: Aydin
authors.forename: Tufan
authors.initials: T
authors.lastname: Tukek
mesh_terms: D000293:Adolescent; D000743:Anemia, Hemolytic; D005260:Female; D006527:Hepatolenticular Degeneration / Q000628:therapy*; D006801:Humans; D008103:Liver Cirrhosis; D010951:Plasma Exchange / Q000379:methods*; D016896:Treatment Outcome