title: Dual-phase 99mTc-MIBI parathyroid imaging reveals synchronous parathyroid adenoma and papillary thyroid carcinoma: a case report.
abstract: The possibility of a coincidental appearance of hyperparathyroidism and thyroid cancer is not often considered because of its low incidence. Here, we present a case of a 49-year-old woman with a parathyroid adenoma coexisting with two sites of papillary thyroid carcinoma. Dual-phase 99mTc-methoxyisobutylisonitrile (MIBI) parathyroid imaging before the operation correctly visualized the site of the parathyroid adenoma. In addition, two papillary thyroid carcinomas showed faint uptake of 99mTc-MIBI on delayed image. Total thyroidectomy and parathyroidectomy of a solitary parathyroid adenoma were performed. The patient subsequently underwent radioiodine-131 ablation and was treated with T4 suppression. This case illustrates the need for clinical awareness of concomitant hyperparathyroidism and thyroid cancer. Dual-phase 99mTc- MIBI parathyroid imaging may be useful for detecting indolent thyroid cancer before it becomes a distinct disease.
authors.affiliation: Department of Nuclear Medicine, Changhua Christian Hospital, Changhua, Taiwan.
authors.forename: Ming-Che
authors.initials: MC
authors.lastname: Chang
authors.forename: Shih-Chuan
authors.initials: SC
authors.lastname: Tsai
authors.forename: Wan-Yu
authors.initials: WY
authors.lastname: Lin
mesh_terms: D002291:Carcinoma, Papillary / Q000175:diagnosis*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000175:diagnosis; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010282:Parathyroid Neoplasms / Q000175:diagnosis*; D017256:Technetium Tc 99m Sestamibi; D013964:Thyroid Neoplasms / Q000175:diagnosis*
chemical_list: D017256:Technetium Tc 99m Sestamibi