Ictal vomiting as an initial symptom of severe myoclonic epilepsy in infancy: a case report.
We report on 3-year-old Japanese twin brothers suffering from ictal vomiting during infancy. Intractable seizures, including generalized tonic-clonic convulsions, and myoclonic seizures persisted in late infancy. The diagnosis of severe myoclonic epilepsy in infancy was confirmed by detecting a mutation in the voltage-gated sodium channel alpha subunit type gene. This is the first case report addressing ictal vomiting as the initial presentation of severe myoclonic epilepsy in infancy.
Hino-Fukuyo
Naomi
N
Department of Pediatrics, Tohoku University School of Medicine, Aoba-ku, Sendai, Japan.
Haginoya
Kazuhiro
K
Togashi
Noriko
N
Uematsu
Mitsugu
M
Kitamura
Taro
T
Kakisaka
Yosuke
Y
Ishitobi
Mamiko
M
Wakusawa
Keisuke
K
Iinuma
Kazuie
K
Oguni
Hirokazu
H
Yamakawa
Kazuhiro
K
Tsuchiya
Shigeru
S
D002675:Child, Preschool; D003937:Diagnosis, Differential; D004200:Diseases in Twins / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D004831:Epilepsies, Myoclonic / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008297:Male; D009154:Mutation; D012640:Seizures; D015222:Sodium Channels / Q000235:genetics; D014839:Vomiting / Q000209:etiology*
D015222:Sodium Channels