False aneurysm of a hepatic artery branch complicating intrahepatic islet transplantation.
Islet transplantation, an innovative treatment strategy for type 1 diabetes mellitus, is a relatively safe procedure, with less morbidity than pancreas transplantation. Vascular injuries have not been reported to date. We report a percutaneous transhepatic intraportal islet transplant infusion that was followed by bleeding from a false aneurysm of an intrahepatic branch of the hepatic artery. The bleeding was controlled by selective embolization. Despite the complication and its treatment, the patient gained insulin independence, which was sustained for 285 days. She is currently on a small dose of insulin with good glycemic control.
Onaca
Nicholas
N
Transplant Services, Baylor University Medical Center, Dallas, TX 75246, USA. nicholao@baylorhealth.edu
Naziruddin
Bashoo
B
Randall
Henry B
HB
Meler
James D
JD
Sanchez
Edmund Q
EQ
Matsumoto
Shinichi
S
Noguchi
Hirofumi
H
Jackson
Andrew
A
Diamond
Norman G
NG
Klintmalm
Goran B
GB
Levy
Marlon F
MF
D017541:Aneurysm, False / Q000209:etiology* / Q000628:therapy; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D004621:Embolization, Therapeutic; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D016381:Islets of Langerhans Transplantation / Q000009:adverse effects*; D008099:Liver / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications / Q000601:surgery