title: Total synthesis of (+)-azinothricin and (+)-kettapeptin.
abstract: Asymmetric total syntheses of (+)-azinothricin and (+)-kettapeptin have been completed through a common new pathway that exploits a highly chemoselective coupling reaction between the fully elaborated cyclodepsipeptide 5 and the glycal activated esters 3 and 4 at the final stages of both respective syntheses.
authors.affiliation: The School of Chemistry & Chemical Engineering, and the Centre for Cancer Research and Cell Biology, Queen's University Belfast (QUB), Stranmillis Road, Belfast BT9 5AG, UK.
authors.forename: Karl J
authors.initials: KJ
authors.lastname: Hale
authors.forename: Soraya
authors.initials: S
authors.lastname: Manaviazar
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: George
authors.forename: Marcus A
authors.initials: MA
authors.lastname: Walters
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Dalby
mesh_terms: D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D047630:Depsipeptides; D004952:Esters; D010455:Peptides; C512876:kettapeptin; C048098:azinothricin; C056791:A 83586C