Tandem dispersion and killing of bacteria from a biofilm.
The combined effects of biofilm dispersion with a 2-aminoimidazole-triazole conjugate and bactericidal activity with a photodynamic inactivation agent suggest a novel combination therapy for treating diverse microbial infections.
Rogers
Steven A
SA
Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA.
Krayer
Michael
M
Lindsey
Jonathan S
JS
Melander
Christian
C
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D018441:Biofilms; D050296:Microbial Viability / Q000187:drug effects; D017319:Photosensitizing Agents / Q000737:chemistry / Q000494:pharmacology; D014230:Triazoles / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D017319:Photosensitizing Agents; D014230:Triazoles