A new flavonol galloylrhamnoside and a new lignan glucoside from the leaves of Koelreuteria henryi Dummer.
A new flavonol galloylrhamnoside, kaempferol 3-O-(2'',3''-di-O-galloyl)-alpha-L: -rhamnopyranoside, and a new lignan glycoside, hinokinin 7-O-beta-D: -glucopyranoside were isolated from the leaves of Koelreuteria henryi, along with 18 known compounds, including six flavonol glycosides (3-8), three lignans (9-11), four chlorophyll derivatives (12-15), two steroids (16, 17), and three aromatic compounds (18-20). The structures were determined on the basis of spectral analysis and chemical evidence. The scavenging effect of 1-8 and 20 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 5, 6, and 20 showed more potent activity than that of trolox.
Lee
Tzong-Huei
TH
College of Pharmacy, Taipei Medical University, No. 250 Wu-Hsing St., Taipei 110, Taiwan.
Chiang
Yuan-Hsiang
YH
Chen
Chin-Hui
CH
Chen
Pi-Yu
PY
Lee
Ching-Kuo
CK
D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D001713:Biphenyl Compounds; D002839:Chromans / Q000494:pharmacology; D004149:Dioxoles / Q000302:isolation & purification / Q000494:pharmacology; D044948:Flavonols / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology*; D005960:Glucosides / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D044949:Kaempferols / Q000302:isolation & purification / Q000494:pharmacology; D017705:Lignans / Q000302:isolation & purification / Q000494:pharmacology; D008516:Medicine, Chinese Traditional; D010851:Picrates; D018515:Plant Leaves; D044945:Proanthocyanidins / Q000302:isolation & purification / Q000494:pharmacology; D029631:Sapindaceae / Q000737:chemistry*; D013057:Spectrum Analysis; D013624:Taiwan
D000975:Antioxidants; D001713:Biphenyl Compounds; D002839:Chromans; D004149:Dioxoles; D044948:Flavonols; D016166:Free Radical Scavengers; D005960:Glucosides; D006027:Glycosides; D044949:Kaempferols; D017705:Lignans; D010851:Picrates; D044945:Proanthocyanidins; C539785:hinokinin 7-O-beta-D-glucopyranoside; C539784:kaempferol 3-O-(2''3''di-O-galloyl)-alpha-L-rhamnopyranoside; C004931:1,1-diphenyl-2-picrylhydrazyl; C010643:6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid