[A medical and economic study about use of hemostatic glues in cardiac surgery].
BACKGROUND
The impact of the use of biological and synthetic glues in cardiac surgery was assessed by an economic and medical study.


METHODS
The observational prospective study had duration of three months. All the patients undergoing cardiac surgery were included in the study. The end points were medical (blood transfusion) and economic (duration and cost of the stay in hospital). There were 2 groups: treated or not by glues.


METHODS
T Student tests.


RESULTS
Among 154 patients, the 2 principal indications were valvular replacement (48%) and coronary artery bypass grafting (37%). Fifty seven (37%) patients received a glue. The number of transfused globular units and the duration of the stay in the intensive care unit were significantly higher (p<0.05) by treated patients.


CONCLUSIONS
Not only the use of glues did not decrease the post-operative bleedings but it increased also the cost of the stay in hospital. Guidelines were validated by the hospital Commission on drugs.
Ameslant
Sandra
S
Pharmacie du Groupe Hospitalier Sud, CHU Amiens, Salouel, France. sandra.ameslant@free.fr
Delgove
Capuccine
C
Tramier
Blaise
B
Lescoat
Halima
H
Caus
Thierry
T
Desablens
Françoise
F
Petit
Abir
A
D000269:Adhesives / Q000191:economics* / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000191:economics* / Q000379:methods*; D005340:Fibrinogen / Q000191:economics / Q000627:therapeutic use; D005602:France; D005976:Glutaral / Q000191:economics / Q000627:therapeutic use; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008875:Middle Aged; D011446:Prospective Studies; D011506:Proteins / Q000191:economics / Q000627:therapeutic use; D013213:Starch / Q000191:economics / Q000627:therapeutic use
D000269:Adhesives; C527600:Arista; C472676:Bio-glue; D011506:Proteins; D005340:Fibrinogen; D013213:Starch; D005976:Glutaral