title: Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report.
abstract: BACKGROUND
  Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes
  
  
  METHODS
  We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls). There are no similar case reports in the literature at this time.
  
  
  CONCLUSIONS
  High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.
authors.affiliation: Faculty of Medicine and Human Sciences, University of Manchester, Wythenshawe Hospital, Manchester, UK. rifatrashid@hotmail.com.
authors.forename: Rifat
authors.initials: R
authors.lastname: Rashid
authors.forename: David W
authors.initials: DW
authors.lastname: Denning