title: Severe bilateral pyramidal tract involvement in a patient with Parry-Romberg syndrome.
abstract: Parry-Romberg syndrome (PRS) is a rare clinical entity of unknown etiology, generally characterized by a slow and progressive atrophy that affects 1 side of the face. A variety of neurologic abnormalities have been shown to coexist with PRS. However, few studies regarding pyramidal tract involvement in this disorder have been reported. We report a unique case, in which the patient presented with bilateral pyramidal tract insult and an unusual sequence of disease onset and progression. This case suggests a rarer variant of PRS, and the neurologic findings indicate that the underlying essential neural degeneration may contribute to the processing of pyramidal tract insult or this syndrome.
authors.affiliation: Department of Neurology, Tangdu Hospital, Fourth Military Medical University, Xi'an City, Shaanxi Province, China.
authors.forename: Jianting
authors.initials: J
authors.lastname: Miao
authors.forename: Rui
authors.initials: R
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Lin
authors.forename: Changjun
authors.initials: C
authors.lastname: Su
authors.forename: Hongzeng
authors.initials: H
authors.lastname: Li
authors.forename: Gesheng
authors.initials: G
authors.lastname: Lei
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Zhuyi
authors.initials: Z
authors.lastname: Li
mesh_terms: D000328:Adult; D005150:Facial Hemiatrophy / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D009410:Nerve Degeneration / Q000209:etiology*; D011712:Pyramidal Tracts / Q000503:physiopathology*