An efficient ultrasound-promoted synthesis of the Baylis-Hillman adducts catalyzed by imidazole and L-proline.
A convenient protocol was developed for the synthesis of the Baylis-Hillman adducts in the presence of weak Lewis base and l-proline at room temperature under ultrasound irradiation. This method provided the products in good to high yields (65-90%) and reasonable reaction times.
Mamaghani
Manouchehr
M
Chemistry Department, Faculty of Sciences, Islamic Azad University, Rasht Branch, Iran. mchem41@gmail.com
Dastmard
Sahar
S
D002384:Catalysis; D007093:Imidazoles / Q000737:chemistry*; D015394:Molecular Structure; D011392:Proline / Q000737:chemistry*; D014465:Ultrasonics
D007093:Imidazoles; C029899:imidazole; D011392:Proline