In vitro studies of cells grown on the superconductor PrO(x)FeAs.
The recent discovery of arsenic-based high temperature superconductors has reignited interest in the study of superconductor: biological interfaces. However, the new superconductor materials involve the chemistry of arsenic and their toxicity remains unclear [Hand, E., 2008. Nature 452 (24), 922]. In this study the possible adverse effects of this new family of superconductors on cells have been examined. Cell culture studies in conjunction with microscopy and viability assays were employed to examine the influence of arsenic-based superconductor PrO(x)FeAs (x=0.75) material in vitro. Imaging data revealed that cells were well adhered and spread on the surface of the superconductor. Furthermore, cytotoxicity studies showed that cells were unaffected during the time-course of the experiments, providing support for the biocompatibility aspects of PrO(x)FeAs-based superconductor material.
Yang
Shaoguang
S
National Laboratory of Microstructures, Nanjing University, China. sgyang@nju.edu.cn
Xie
Yuxuan
Y
Yang
Wenrong
W
Zheng
Rongkun
R
Stevens
Frankie
F
Korkmaz
Emine
E
Weiss
Anthony S
AS
Ringer
Simon P
SP
Braet
Filip
F
D001152:Arsenicals; D002448:Cell Adhesion; D049109:Cell Proliferation; D002470:Cell Survival; D002478:Cells, Cultured; D004847:Epithelial Cells / Q000502:physiology*; D005290:Ferric Compounds; D005347:Fibroblasts / Q000502:physiology*; D006367:HeLa Cells; D006801:Humans
D001152:Arsenicals; D005290:Ferric Compounds