title: [Xianling Gubao Capsule improves semen quality].
abstract: OBJECTIVE
  To observe the effect of the compound Chinese traditional drug Xianling Gubao Capsule on the semen quality of infertile males.
  
  
  METHODS
  We treated 66 infertile men with Xianling Gubao Capsule for 24 months, and analyzed the semen quality and sperm morphology before and after the treatment.
  
  
  RESULTS
  Two months after the medication, sperm concentration was increased by a small margin, but no statistically significant changes were observed in sperm vitality and motility (P > 0.05), the rate of morphologically normal sperm was significantly raised from 25.8% before treatment to 57.6% (P < 0.05) in those with the normal rate > or = 15%, but decreased from 53.0% to 25.8% (P < 0.05) in those with the normal rate < 9%. Among the 7 cases of oligospermia, the rate of morphologically normal sperm was elevated to an average of 10.9% after the 4-month medication, significantly different from the baseline rate of 5.8% (P < 0.05). Five spontaneous pregnancies and 1 successful IVF-ICSI were achieved during the treatment.
  
  
  CONCLUSIONS
  Xianling Gubao Capsule can improve semen quality and significantly increase the percentage of morphologically normal sperm.
authors.affiliation: Human Sperm Bank, Huaxi Second Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
authors.forename: Min
authors.initials: M
authors.lastname: Jiang
authors.forename: Zi-Yan
authors.initials: ZY
authors.lastname: Han
authors.forename: Huan-Xun
authors.initials: HX
authors.lastname: Yue
authors.forename: Fu-Ping
authors.initials: FP
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Lin
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: She
mesh_terms: D000328:Adult; D002214:Capsules; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D008517:Phytotherapy; D011247:Pregnancy; D055101:Semen Analysis; D013076:Sperm Count; D013081:Sperm Motility; D016896:Treatment Outcome
chemical_list: D002214:Capsules