Biosynthetic studies of spiroleptosphol.
Studies of the biosynthesis of spiroleptosphol (1) revealed that 1 comprised a heptaketide (C1, C5-C10, and C12-C18 moiety), two methyl carbons (C19 and C20) from methionine, and a C(3) unit (C3, C4, and C11 moiety) derived through the TCA cycle.
Murakami
Takanori
T
Faculty of Agriculture and Life Science, Hirosaki University, 3-Bunkyo-cho, Hirosaki 036-8561, Japan.
Takada
Noboru
N
Hashimoto
Masaru
M
D001203:Ascomycota / Q000737:chemistry; D002952:Citric Acid Cycle; D018360:Crystallography, X-Ray; D008715:Methionine / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
D013141:Spiro Compounds; C532933:spirolephtoshol; D008715:Methionine