Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation.
Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle-protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion.
Fu
Aihua
A
Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA. aihuafu@stanford.edu
Hu
Wei
W
Xu
Liang
L
Wilson
Robert J
RJ
Yu
Heng
H
Osterfeld
Sebastian J
SJ
Gambhir
Sanjiv S
SS
Wang
Shan X
SX
D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques; D008280:Magnetics; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry*; D011506:Proteins / Q000138:chemical synthesis / Q000737:chemistry*
D052157:Aptamers, Nucleotide; D011506:Proteins