title: Gadolinium enhancement of the lumbar roots in a case of ALS.
abstract: We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA. young.nathan@mayo.edu <young.nathan@mayo.edu>
authors.forename: Nathan P
authors.initials: NP
authors.lastname: Young
authors.forename: Ruple S
authors.initials: RS
authors.lastname: Laughlin
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Sorenson
mesh_terms: D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000473:pathology*; D017809:Fatal Outcome; D005682:Gadolinium; D006801:Humans; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D013126:Spinal Nerve Roots / Q000473:pathology*
chemical_list: D005682:Gadolinium