title: Central pontine myelinolysis despite slow sodium rise in a case of severe community-acquired hyponatraemia.
abstract: The management of severe hyponatraemia is a challenging task for intensivists. It should be based on underlying pathophysiology, especially the duration of hyponatraemia (acute vs. chronic) and the presence or absence of severe neurologic symptoms. We describe a case of severe community-acquired hyponatraemia in which central pontine myelinolysis developed several days after discharge from the intensive care unit, despite a gradual increase of plasma sodium levels during the intensive care unit stay.
authors.affiliation: Department of Anesthesiology and Intensive Care, Charité - University Hospital Berlin, Campus Charité Mitte, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Schuster
authors.forename: S
authors.initials: S
authors.lastname: Diekmann
authors.forename: R
authors.initials: R
authors.lastname: Klingebiel
authors.forename: T
authors.initials: T
authors.lastname: Volk
mesh_terms: D003422:Critical Care; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000150:complications* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis / Q000209:etiology*; D011188:Potassium / Q000097:blood; D011859:Radiography; D012964:Sodium / Q000097:blood*; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000000981:diagnostic imaging
chemical_list: D012964:Sodium; D011188:Potassium