title: Recording with microchannel electrodes in a noisy environment.
abstract: Microchannels containing electrodes have a number of favourable properties that make them potentially suitable as the basis of a peripheral nerve interface design. In this study we have evaluated microchannel recording in vitro in the presence of a realistic simulation of electrical interference from musculature adjacent to an implanted interface. Tripolar recording and high-pass filtration both help improve signal discrimination. At high noise levels designed to replicate the effects of intense muscular activity, a combination of both these techniques is required, and only signals in larger axons can be recovered.
authors.affiliation: Cambridge Centre for Brain Repair, University of Cambridge, Cambridge, CB2 2PY, UK. jjf30@cam.ac.uk
authors.forename: James J
authors.initials: JJ
authors.lastname: FitzGerald
authors.forename: Stephanie P
authors.initials: SP
authors.lastname: Lacour
authors.forename: James W
authors.initials: JW
authors.lastname: Fawcett
mesh_terms: D000465:Algorithms; D000818:Animals; D016477:Artifacts; D004567:Electrodes, Implanted; D004576:Electromyography / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008839:Microelectrodes; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted