title: Full recovery of Takotsubo cardiomyopathy (apical ballooning) in two days.
abstract: Takotsubo cardiomyopathy (TTC) is a new clinical entity characterised by acute but rapidly reversible left ventricular systolic dysfunction. This case report demonstrates the unique finding of a complete normalization of left ventricular function in a patient with TTC in only 36 h documented by cardiac magnetic resonance imaging. To our best knowledge, this is the most rapid complete recovery of left ventricular apical ballooning reported, yet. Medical management of our patient included optimized antihypertensive therapy with intravenous administration of the α-1-adrenergic blocker urapidil and the ß-blocker bisoprolol in highest recommended doses. Although optimal management of TTC has not been established, α- and β-blockade may be beneficial for rapid recovery of TTC and may be protective against the recurrence of stress-related left ventricular dysfunction due to acute and sudden catecholamine excess.
authors.forename: Ingo
authors.initials: I
authors.lastname: Eitel
authors.forename: Christian
authors.initials: C
authors.lastname: Lücke
authors.forename: Florian
authors.initials: F
authors.lastname: Behrendt
authors.forename: Mahdi
authors.initials: M
authors.lastname: Sareban
authors.forename: Matthias
authors.initials: M
authors.lastname: Gutberlet
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schuler
authors.forename: Holger
authors.initials: H
authors.lastname: Thiele
mesh_terms: D018674:Adrenergic Antagonists / Q000627:therapeutic use*; D000368:Aged; D057791:Cardiac Imaging Techniques; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D012074:Remission Induction; D054549:Takotsubo Cardiomyopathy / Q000188:drug therapy* / Q000473:pathology*; D013997:Time Factors; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000473:pathology
chemical_list: D018674:Adrenergic Antagonists