title: Survey of antibiogram tests in cholera patients in the 2005 epidemic in Hamadan, Islamic Republic of Iran.
abstract: An analytical cross-sectional study determined the serogroups and serotypes of Vibrio cholerae, and their antibiotic resistance rates, in the 2005 cholera epidemic in Hamadan. All 190 patients with positive stool cultures had V. cholerae serogroup O1, biotype El Tor and serotype Inaba positive. Of 60 cases selected randomly for antibiogram testing, sensitivity to norfloxacin, ciprofloxacin, kanamycin, amikacin, tetracycline and doxycycline was 97%, 92%, 88%, 85%, 77% and 67% respectively. Resistance to furazolidone, trimethoprim-sulfamethoxazole and erythromycin was 100%, 98% and 62% respectively. Comparison with the results of the 1998 epidemic suggests a worrying increase in the resistance of V. cholerae to erythromycin, doxycycline and ciprofloxacin.
authors.affiliation: Department of Infectious Diseases, Sina Hospital, Hamadan University of Medical Sciences, Hamadan, Islamic Republic of Iran. faribakeramaty@yahoo.com
authors.forename: F
authors.initials: F
authors.lastname: Keramat
authors.forename: S H
authors.initials: SH
authors.lastname: Hashemi
authors.forename: M
authors.initials: M
authors.lastname: Mamani
authors.forename: M
authors.initials: M
authors.lastname: Ranjbar
authors.forename: H
authors.initials: H
authors.lastname: Erfan
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology / Q000382:microbiology; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D007492:Iran / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012703:Serotyping; D017678:Sex Distribution; D014734:Vibrio cholerae / Q000145:classification*