title: A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery.
abstract: Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.
authors.affiliation: Department of Cardiothoracic Surgery, Blackpool Victoria Hospital, Blackpool, United Kingdom. russellmillner@btinternet.com
authors.forename: Russell W J
authors.initials: RW
authors.lastname: Millner
authors.forename: Alan S
authors.initials: AS
authors.lastname: Lockhart
authors.forename: Helen
authors.initials: H
authors.lastname: Bird
authors.forename: Christos
authors.initials: C
authors.lastname: Alexiou
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control; D048271:Chitosan / Q000008:administration & dosage*; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods; D005500:Follow-Up Studies; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013908:Thoracotomy / Q000009:adverse effects* / Q000379:methods; D016896:Treatment Outcome; D014950:Wounds, Penetrating / Q000175:diagnosis / Q000628:therapy
chemical_list: D006490:Hemostatics; D048271:Chitosan