title: Acute acalculous cholecystitis with pericholecystitis in a patient with Epstein-Barr Virus infectious mononucleosis.
abstract: BACKGROUND
  Acute acalculous cholecystitis is a rare complication of Epstein-Barr virus mononucleosis and involves thickening of the gallbladder wall.
  
  
  METHODS
  We describe the case of a 22-year-old woman with acute acalculous cholecystitis and pericholecystitis associated with Epstein-Barr virus primary infection. Surgical intervention was not performed, even though gallbladder perforation was suspected. The patient was treated conservatively with careful monitoring, including repeated ultrasonographic examinations.
  
  
  CONCLUSIONS
  Epstein-Barr virus infections are usually self-limited, and surgical treatment of acute acalculous cholecystitis should only be considered when the ultrasonographic criteria persist on follow-up examinations or when they deteriorate. This is the first report of a severe course of acute acalculous cholecystitis with suspected gallbladder perforation associated with infectious mononucleosis.
authors.affiliation: Charles University in Prague, 1st Medical Faculty, 3rd Department of Infectious and Tropical Diseases, Prague, Czech Republic. chalupap@fnb.cz
authors.forename: Pavel
authors.initials: P
authors.lastname: Chalupa
authors.forename: Miroslav
authors.initials: M
authors.lastname: Kaspar
authors.forename: Michal
authors.initials: M
authors.lastname: Holub
mesh_terms: D042101:Acalculous Cholecystitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000821:virology*; D000328:Adult; D041881:Cholecystitis, Acute / Q000150:complications* / Q000000981:diagnostic imaging / Q000821:virology*; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000000981:diagnostic imaging / Q000821:virology; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000821:virology*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography