Calcified right ventricular thrombus and antiphospholipid syndrome.
Antiphospholipid syndrome has been associated with venous and arterial thrombotic events but intracardiac thrombosis is rare. We describe a case about a 30-year-old woman, admitted with a 6-month history of arthralgia, fatigue, and intermittent fever. Subsequent investigation revealed the presence of a large and calcified mass in the right ventricular outflow tract attached to the subvalvular tricuspid apparatus. Cardiac surgery was performed and histological examination demonstrated it to be composed entirely of calcified thrombus. Screening laboratory evaluation for hypercoagulable states confirmed the diagnosis of antiphospholipid syndrome.
de Agustín
Jose Alberto
JA
Cardiovascular Institute, San Carlos University Hospital, Madrid, Spain. albertutor@hotmail.com
Nuñez-Gil
Iván Javier
IJ
Ruiz-Mateos
Borja
B
Manzano
Maria del Carmen
Mdel C
Vivas
David
D
de Isla
Leopoldo Pérez
LP
Zamorano
Jose
J
Macaya
Carlos
C
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D002114:Calcinosis / Q000175:diagnosis* / Q000601:surgery; D017548:Echocardiography, Transesophageal; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008279:Magnetic Resonance Imaging; D011651:Pulmonary Artery; D013927:Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome