[Research progress on effect of coumarins compounds in anti-tumor].
Coumarins are a group of important natural compounds, and have been found to have multi-biological activities such as anti-HIV, anti-tumor, anti-hypertension, anti-arrhythmia, anti-osteoporosis, assuaging pain, preventing asthma and antisepsis. One of which is its anti-tumor effect and that is a research focus on. Therefore, we believe that it is necessaryto carry out further studies on the effect of coumarins compounds in anti-tumor. Investigation should emphasize on improving techniques for extraction and separation, searching the effective precursory compound, and synthesizing and screening out courmarin derivatives with high activity and low toxicity. Here the recent research progress in anti-tumor effect of coumarins compounds is reviewed.
Hao
Guang
G
College of Animal Sciences and Medicine, Inner Mongolia Agricultural, Hohhot 010018, China.
Wang
Zhen-Guo
ZG
Fu
Wen-Yan
WY
Yang
Ying
Y
D000889:Anti-Arrhythmia Agents / Q000494:pharmacology / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D003374:Coumarins / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
D000889:Anti-Arrhythmia Agents; D019380:Anti-HIV Agents; D000959:Antihypertensive Agents; D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins