title: Assessment of left ventricular function parameters with a new three-dimensional shape model.
abstract: OBJECTIVE
  To evaluate a 3D model of the left ventricle (LV) which allows calculation of LV function parameters on the basis of both short axis (SA) and long axis (LA) cine acquisitions. Comparison with the conventional Simpson's rule method in a volunteer and patient collective.
  
  
  METHODS
  Cine imaging was performed with a prospectively triggered SSFP sequence: trueFISP: TR 3.6 msec, TE 1.8 msec, bFFE: TR 3.0 msec, TE 1.4 msec, flip angle 60 degrees , resolution 1.37 x 1.37 mm, slice thickness 8 mm, gap 2 mm in SA orientation from apex to basis and in radial LA orientation (spacing 15 degrees) in 11 volunteers and 27 patients with mitral valve insufficiency. Five different volume computations were compared: Simpson's rule based on all SA slices (M0), 3D shape model based on all SA slices (M1a), 3D shape model based on 3 SA slices (M1b), 3D shape model based on all SA and LA slices (M2a), and 3D shape model based on 3 SA slices and 1 LA slice (M2b).
  
  
  RESULTS
  M 0 and M 1a give similar results (r: 0.99, b: 0.98). M 2a produces larger volumes than M 0 (b: 0.85) due to the inclusion of the LA contours. M 1b effectively reproduces the volumes computed with M 0 (r: 0.99, b: 1.02). M 2b effectively reproduces the volumes computed with M 2a (r: 0.99, b: 0.94). M 2b and M 0 give similar results in the patient collective (r: 0.99, b: 0.97).
  
  
  CONCLUSIONS
  The proposed 3D shape model allows merging of information acquired in different orientations and thus the combination of SA and LA contours with better coverage of the left ventricle. It provides a suitable fit with a reduced number of segmented contours.
authors.affiliation: Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Hamburg Eppendorf. pmbansmann@gmx.de
authors.forename: P M
authors.initials: PM
authors.lastname: Bansmann
authors.forename: J
authors.initials: J
authors.lastname: Sénégas
authors.forename: K
authors.initials: K
authors.lastname: Muellerleile
authors.forename: G
authors.initials: G
authors.lastname: Lund
authors.forename: J
authors.initials: J
authors.lastname: Kemper
authors.forename: G
authors.initials: G
authors.lastname: Adam
authors.forename: A
authors.initials: A
authors.lastname: Stork
mesh_terms: D000328:Adult; D003198:Computer Simulation; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016277:Ventricular Function, Left / Q000502:physiology*