[Statistical analysis of residues of heavy metals in Chinese crude drugs].
OBJECTIVE
To analyze the residues of heavy metals in Chinese crude drugs.


METHODS
The SPSS 13.0 software was used to analyze the data of Cu, Pb, As, Cd, Hg collected in literatures. And, Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations was used as the standard to evaluate the pollution condition of Cu, Pb, As, Cd, Hg in Chinese crude drugs.


RESULTS
Chinese crude drugs were contaminated by heavy metals in different levels. The content of Cu, Pb, As, Cd, Hg exceeded the limit of the standard and the percentage was 21.0%, 12.0%, 9.7%, 28.5%, 6.9%, respectively; the phenomena of two, three and four metals exceeding limited standard simultaneity in a drug were also found and the percentage was 4.6%, 1.5%, 0.7%, respectively; the content of heavy metals in Radix Platycodi, Radix Asari and Rhizoma Coptidis was higher among the thirty-six Chinese crude drugs; All of the content of five heavy metals in Barbary Fructus Lycii Rhizoma Anemones Raddeanae, Radix Panacis Quiquefolii and Fructus Aurantii were below the limit; The pollution levels of heavy metals in different locality were different; The content of Cu, Pb in cultivated Chinese crude drugs was higher than that in wild Chinese crude drugs, while the content of As in wild Chinese crude drugs was higher than that in cultivated Chinese crude drugs.


CONCLUSIONS
The pollution levels of heavy metals in Chinese crude drugs were detailed reported in this paper. And it provided ways for the further study of heavy metals in Chinese crude drugs.
Han
Xiao-Li
XL
Key Lab of Natural Drug and Immune Engineering, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475001, China.
Zhang
Xiao-Bo
XB
Guo
Lan-Ping
LP
Huang
Lu-Qi
LQ
Li
Ming-Jing
MJ
Liu
Xiu-Hua
XH
Sun
Yu-Zhang
YZ
Lv
Jin-Rong
JR
D002104:Cadmium / Q000032:analysis; D003300:Copper / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007854:Lead / Q000032:analysis; D008628:Mercury / Q000032:analysis; D019216:Metals, Heavy / Q000032:analysis*
D004365:Drugs, Chinese Herbal; D019216:Metals, Heavy; D002104:Cadmium; D007854:Lead; D003300:Copper; D008628:Mercury