Has prolactin a role in the hypogonadal status of HIV-infected patients?
Most cases of hypogonadism in human immunodeficiency virus (HIV) infection are of hypophyseal- hypothalamic origin, and hyperprolactinemia, also commonly observed in HIV-infected patients, may cause hypogonadism. We studied 188 HIV-infected men who had simultaneous determinations of gonadal and hypophyseal hormones, and we found that prolactin levels were independently predictive of hypogonadism in multivariate analysis.
Collazos
Julio
J
Section of Infectious Diseases, Hospital de Gáldacano-Usánsolo, Vizcaya, Spain. med003033@saludalia.com
Esteban
Margarita
M
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D015331:Cohort Studies; D015658:HIV Infections / Q000097:blood / Q000150:complications*; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications*; D007006:Hypogonadism / Q000150:complications* / Q000453:epidemiology; D007118:Immunoassay; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011388:Prolactin / Q000378:metabolism*; D012189:Retrospective Studies; D013739:Testosterone / Q000097:blood; D019562:Viral Load
D013739:Testosterone; D011388:Prolactin