title: Evaluation of w values for carbon beams in air, using a graphite calorimeter.
abstract: Despite recent progress in carbon therapy, accurate values for physical data such as the w value in air or stopping power ratios for ionization chamber dosimetry have not been obtained. The absorbed dose to graphite obtained with the graphite calorimeter was compared with that obtained using the ionization chambers following the IAEA protocol in order to evaluate the w values in air for mono-energetic carbon beams of 135, 290, 400 and 430 MeV/n. Two cylindrical chambers (PTW type 30001 and PTW type 30011, Farmer) and two plane-parallel chambers (PTW type 23343, Markus and PTW type 34001, Roos) calibrated by the absorbed dose to graphite and exposure to the (60)Co photon beam were used. The comparisons to our calorimeter measurements revealed that, using the ionization chambers, the absorbed dose to graphite comes out low by 2-6% in this experimental energy range and with these chamber types and calibration methods. In the therapeutic energy range, the w values in air for carbon beams indicated a slight energy dependence; we, however, assumed these values to be constant for practical use because of the large uncertainty and unknown perturbation factors of the ionization chambers. The w values in air of the carbon beams were evaluated to be 35.72 J C(-1) +/- 1.5% in the energy range used in this study. This value is 3.5% larger than that recommended by the IAEA TRS 398 for heavy-ion beams. Using this evaluated result, the absorbed dose to water in the carbon beams would be increased by the same amount.
authors.affiliation: Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1, Anagawa, Inage-ku, Chiba 263-8555, Japan. m_sakama@nirs.go.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Sakama
authors.forename: Tatsuaki
authors.initials: T
authors.lastname: Kanai
authors.forename: Akifumi
authors.initials: A
authors.lastname: Fukumura
authors.forename: Kyoko
authors.initials: K
authors.lastname: Abe
mesh_terms: D000388:Air; D002151:Calorimetry / Q000295:instrumentation / Q000379:methods; D002244:Carbon / Q000737:chemistry* / Q000627:therapeutic use; D006108:Graphite; D011839:Radiation, Ionizing; D011879:Radiotherapy Dosage; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water; D002244:Carbon; D006108:Graphite