Electron ionization mass spectrometric study of substituted alloxazine-5-oxides and iso-alloxazine-5-oxide.
The fragmentation pathways in electron ionization (EI) mass spectra of a series of new N(5)-oxides of alloxazines and iso-alloxazine are presented, and compared with those of substituted alloxazines and iso-alloxazine. The EI mass spectra of these compounds showed characteristic fragmentation pathways A, B and C, started by the ejection of atomic oxygen, a HNCO molecule and an OH(*) radical, respectively. On the basis of B/E and B(2)/E spectra, the mechanism of elimination of the OH(*) radical is discussed. The influence of the methyl substituent in the benzene ring of alloxazine on the mass fragmentation pathways is described.
Prukała
Dorota
D
Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland. dprukala@amu.edu.pl
Sikorski
Marek
M
D000970:Antineoplastic Agents / Q000737:chemistry*; D004583:Electrons; D005415:Flavins / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D000970:Antineoplastic Agents; D005415:Flavins; D010087:Oxides; C008173:isoalloxazine