Correlation of 2-hour and 4-hour urinary proteins with 24-hours proteinuria in hospitalized patients with preeclampsia.
OBJECTIVE
To determine whether 2-hour and 4-hour urinary proteins correlate with 24-hour proteinuria in patients with preeclampsia.


METHODS
Protein estimation was done from 2-hour, 4-hour, and 24-hour urine samples in 50 women with preeclampsia and the results were compared.


RESULTS
Statistical analysis demonstrated no significant difference in the mean protein excretion when comparing the 2-hour values with the 24-hour and further comparing 4-hour values with the 24-hour value. The values of 2-hour and 4-hour urine proteins in total volume (TV) correlated well with 24-hour value for mild & severe disease (p<0.001). Amount of the protein excretion in 2-hour and 4-hour samples predicted mild preeclampsia with positive predictive value of 100% and negative predictive value (NPV) of 80%. NPV of both the samples for severe preeclampsia was 100%.


CONCLUSIONS
2-hour and 4-hour proteinuria can be used for initial assessment of preeclampsia thereby avoiding the inconvenience and delay in treatment.
Soni
S
S
Department of Obstetrics, Post-Graduate Institute of Medical Education & Research, Chandigarh, India.
Aggarwal
N
N
Dhaliwal
L
L
Wangkheimayum
S
S
D000328:Adult; D001510:Bed Rest; D002940:Circadian Rhythm; D005260:Female; D006760:Hospitalization; D006801:Humans; D011225:Pre-Eclampsia / Q000652:urine*; D011247:Pregnancy; D011507:Proteinuria / Q000652:urine*; D013997:Time Factors; D055815:Young Adult