Sphingolipids and membrane environments for caveolin.
Caveolin-1, and probably also -2 and -3, can organize multimolecular membrane complexes involved in transmembrane traffic, cell adhesion and signal transduction. In this review, we discuss on the importance of caveolin membrane environment in regulating the architecture and function of such complexes, with a special emphasis on the role of sphingolipids.
Sonnino
Sandro
S
Center of Excellence on Neurodegenerative Diseases, Department of Medical Chemistry, Biochemistry and Biotechnology, University of Milan, 20090 Segrate, Milano, Italy.
Prinetti
Alessandro
A
D000818:Animals; D022461:Caveolins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D008954:Models, Biological; D013107:Sphingolipids / Q000378:metabolism
D022461:Caveolins; D008565:Membrane Proteins; D013107:Sphingolipids