title: [Genital herpes].
abstract: Genital herpes (GH) is the second leading cause of sexual transmitted disease in women and the third in men. About 40% of female genital herpes is caused by herpes simplex virus type 1 (HSV-1) and the remaining by type-2 (HSV-2). Fifty four percent of primary female GH was caused by type-1, whereas 86% of recurrent cases by type-2. For rapid diagnosis of GH, LAMP(loop-mediated isothermal amplification), HSV DNA nuclear amplification method developed in Japan, was applied and favorable results were obtained. We compared three gG based type specific antibody kits (Platteria, HerpeSelect and Captia). Among these, Platteria was shown to be most sensitive and specific.
authors.affiliation: Department of Obstetrics and Gynecology, Teikyo University Faculty of Medicine, Mizonokuchi Hospital.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kawana
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000031:analogs & derivatives; D000328:Adult; D000367:Age Factors; D000998:Antiviral Agents / Q000008:administration & dosage; D005260:Female; D006558:Herpes Genitalis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology; D018259:Herpesvirus 1, Human; D018258:Herpesvirus 2, Human; D006801:Humans; D008297:Male; D008875:Middle Aged; D021141:Nucleic Acid Amplification Techniques; D016133:Polymerase Chain Reaction; D055502:Secondary Prevention; D000077483:Valacyclovir; D014633:Valine / Q000008:administration & dosage / Q000031:analogs & derivatives; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir