title: [A dynamic analysis on incidence and trend of HIV-1 epidemics among intravenous drug users, attendants at the STD clinics and pregnant women in Yunnan province, China].
abstract: OBJECTIVE
  BED-CEIA assay was used in HIV/AIDS surveillance sentinel sites to identify recent HIV-1 infection, to estimate HIV-1 incidence and to understand the epidemic trends in Yunnan province.
  
  
  METHODS
  Serum specimens were collected from IDUs in sentinel sites, attendants in STD clinics and pregnant women under a cross sectional study from 2000 to 2007. Specimens confirmed as HIV-1 positive were tested with BED-CEIA to find recent HIV-1 infection, then the annual HIV-1 incidence for each group was calculated and the trends of HIV-1 incidence observed.
  
  
  RESULTS
  144 780 serum specimens were collected and 4932 of them were confirmed as HIV-1 positive. 4678 positive specimens were tested with BED-CEIA and 723 ont of them were identified as recent infections. Specimens from the two years were combined for testing. The average HIV-1 prevalence among IDUs was 18.2% - 26.9% from 2000 to 2007 and the annual incidence were 14.65%, 6.21%, 4.06%, 2.23% respectively. The average HIV-1 prevalence among attendants in STD clinics was 1.6% - 3.2% and the annual incidence rates were 1.46%, 0.76%, 0.52%, 0.33% respectively. The average HIV-1 prevalence among pregnant women was 0.2% - 0.5% and the annual incidence rates were 0.16%, 0.11%, 0.10%, 0.09% respectively.
  
  
  CONCLUSIONS
  HIV-1 incidence rates among IDUs, STDs and pregnant women showed a steady decrease.
authors.affiliation: Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
authors.forename: Li
authors.initials: L
authors.lastname: Yang
authors.forename: Yan-ling
authors.initials: YL
authors.lastname: Ma
authors.forename: Hong-bing
authors.initials: HB
authors.lastname: Luo
authors.forename: Man-hong
authors.initials: MH
authors.lastname: Jia
authors.forename: Chao-jun
authors.initials: CJ
authors.lastname: Yang
authors.forename: Min-jie
authors.initials: MJ
authors.lastname: Wang
authors.forename: Hui-chao
authors.initials: HC
authors.lastname: Chen
authors.forename: Sheng
authors.initials: S
authors.lastname: Shen
authors.forename: Jing-yuan
authors.initials: JY
authors.lastname: Mei
authors.forename: Fei
authors.initials: F
authors.lastname: Tian
authors.forename: Yu-hua
authors.initials: YH
authors.lastname: Shi
authors.forename: Wen-yun
authors.initials: WY
authors.lastname: Yan
authors.forename: Lin
authors.initials: L
authors.lastname: Lu
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D015995:Prevalence; D018571:Sentinel Surveillance; D012749:Sexually Transmitted Diseases / Q000453:epidemiology*; D015819:Substance Abuse, Intravenous / Q000453:epidemiology*