title: High frequency chest compression effects on cardio-respiratory interaction.
abstract: In this study, we present a quantitative approach to the analysis of the HFCC effect on heart rate changes in the respiratory stage according to different pulsation conditions with HFCC pulsation and without HFCC pulsation. We have shown that the heart rate increases with higher pressure settings revealing different patterns depending on the respiration stages. For our interaction study of how the heart and lungs were affected by HFCC, phase synchronization was considered and compared under different conditions which determine the real biological phenomenon for nonlinear or linear oscillatory coupling. The subject for this study was young and healthy, so these preliminary results should be verified with more detailed studies from abundant subjects to increase HFCC efficacy for lung disease patients. Interestingly, the indication or tracking of heart rate changes, respiration rate changes, or synchronization epoch can be the standard index for how much the cardiac and respiratory system improve using HFCC during therapy time or after therapy time.
authors.affiliation: Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA. jongwona@gmail.com
authors.forename: Jongwon
authors.initials: J
authors.lastname: Lee
authors.forename: Yong Wan
authors.initials: YW
authors.lastname: Lee
authors.forename: Warren J
authors.initials: WJ
authors.lastname: Warwick
mesh_terms: D035641:Chest Wall Oscillation / Q000379:methods*; D003198:Computer Simulation; D003201:Computers; D004594:Electrophysiology / Q000379:methods; D006339:Heart Rate; D006801:Humans; D008168:Lung / Q000502:physiology*; D015233:Models, Statistical; D009991:Oscillometry; D010100:Oxygen / Q000378:metabolism; D011336:Probability; D012123:Pulmonary Ventilation / Q000502:physiology*; D012119:Respiration; D015656:Respiratory Mechanics / Q000502:physiology; D013997:Time Factors
chemical_list: D010100:Oxygen