title: Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H centers.
abstract: An sp(2)/sp(3) get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl C(sp(2))-H and a C(sp(3))-H center (see scheme; DMF = N,N-dimethylformamide).
authors.affiliation: Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland.
authors.forename: Yi-Xia
authors.initials: YX
authors.lastname: Jia
authors.forename: E Peter
authors.initials: EP
authors.lastname: Kündig
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D005609:Free Radicals / Q000138:chemical synthesis / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D000078183:Oxindoles
chemical_list: D005609:Free Radicals; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D002244:Carbon; D003300:Copper; D006859:Hydrogen