title: A case of natural killer cell lymphoma presenting with bilateral pleural effusions and hemophagocytic lymphohistocytosis.
abstract: Natural killer (NK) cell lymphoma of lung is very rare. We report a case of NK cell lymphoma presented in a 17-year-old male with bilateral pleural effusions and hemophagocytic lymphohistocytosis. Morphologic and immunohistochemical tests revealed an association of NK cell lymphoma with Epstein-Barr virus. A literature review helped identify other cases of patients with NK cell lymphoma, their treatment and outcomes.
authors.affiliation: Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Chun-Fu
authors.initials: CF
authors.lastname: Tai
authors.forename: Luan Yin
authors.initials: LY
authors.lastname: Chang
authors.forename: Dong-Tsamn
authors.initials: DT
authors.lastname: Lin
authors.forename: Kai-Hsin
authors.initials: KH
authors.lastname: Lin
authors.forename: Shiann-Tarng
authors.initials: ST
authors.lastname: Jou
authors.forename: Yung-Li
authors.initials: YL
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D004279:DNA, Viral / Q000235:genetics; D017809:Fatal Outcome; D004854:Herpesvirus 4, Human / Q000235:genetics; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D008223:Lymphoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D008297:Male; D016066:Pleural Effusion, Malignant / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D004279:DNA, Viral