title: Imaging forearm blood flow with pulse-ox gated electrical impedance tomography.
abstract: Assessing peripheral vasculature health has the potential to impact clinical decision making in terms of treating patients with cardiovascular disease. The electrical conductivity of certain tissue regions within the forearm change as blood vessels undergo pulsatile dilation in synchrony with the beating of the heart. We use dynamic electrical impedance tomography (EIT) gated to the peak of a pulse oxymetry plethysmography waveform to image this temporally varying spatial conductivity. A phantom imaging experiment is presented showing that small conductivity changes of less than 1 mm are detectable using the developed dynamic EIT system. This system is used to image a volunteer's forearm during resting cardiovascular activity. Similar structures are observed in the plethysmography trace and the temporally varying conductivity. Spectral analysis shows that the maximum amplitude is occurring at frequencies of 1.19 Hz and 1.21 Hz for the plethysmography trace and conductivity trace, respectively. This preliminary data suggests that EIT may be sensitive enough to visualize cardiac-based pulsatility in the peripheral vessels of the forearm.
authors.affiliation: Thayer School of Engineering at Dartmouth College, Hanover, NH 03755, USA. ryan.halter@dartmouth.edu
authors.forename: R J
authors.initials: RJ
authors.lastname: Halter
authors.forename: A
authors.initials: A
authors.lastname: Hartov
authors.forename: K D
authors.initials: KD
authors.lastname: Paulsen
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005542:Forearm / Q000098:blood supply / Q000502:physiology*; D006801:Humans; D010092:Oximetry / Q000295:instrumentation*; D010992:Plethysmography, Impedance / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014054:Tomography / Q000295:instrumentation*