Two new solanapyrone analogues from the endophytic fungus Nigrospora sp. YB-141 of Azadirachta indica.
Two new solanapyrone analogues, solanapyrones N and O (1 and 2, resp.), and three known compounds, solanapyrone C (3), nigrosporalactone (4), and phomalactone (5), were isolated from the fermentation culture of Nigrospora sp. YB-141, an endophytic fungus isolated from Azadirachta indica A. Juss. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. The antifungal activities of 1-5 towards seven phytopathogenic fungi were tested. Most of the compounds exhibited no or only weak antifungal activities.
Wu
Shao-Hua
SH
Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, Yunnan, P. R. China. shwu123@126.com
Chen
You-Wei
YW
Shao
Shi-Cheng
SC
Wang
Li-Dong
LD
Yu
Ying
Y
Li
Zhi-Ying
ZY
Yang
Li-Yuan
LY
Li
Shao-Lan
SL
Huang
Rong
R
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D031601:Azadirachta / Q000382:microbiology*; D009682:Magnetic Resonance Spectroscopy; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification
D000935:Antifungal Agents; D009281:Naphthalenes; D011753:Pyrones; C539329:solanapyrone N; C539330:solanapyrone O