title: A LC-MS method allowing the analysis of HMX and RDX present at the picogram level in natural aqueous samples without a concentration step.
abstract: The introduction of chloroform into the nebulising gas of a LC/MS electrospray interface (ESI), in a perfectly controlled way, leads to the formation of intense adducts ([M+Cl](-)) when a mobile phase containing HMX (1,3,5,7-tetranitro-1,3,5,7-tetrazacyclooctane or octogen) and RDX (1,3,5-trintro-1,3,5-triazacyclohexane or hexogen) is eluted. This LC/MS method allows the direct analysis of aqueous samples containing HMX and RDX at the pictogram level without a concentration step. The method is used to determine HMX and RDX concentrations in ground water samples from a military site.
authors.affiliation: Commissariat à l'Energie Atomique, Centre DAM Ile-de-France, Bruyères-le-Châtel, 91297 Arpajon Cedex, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Vigneau
authors.forename: Xavier
authors.initials: X
authors.lastname: Machuron-Mandard
mesh_terms: D001392:Azocines / Q000032:analysis*; D002725:Chloroform / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D053834:Explosive Agents / Q000737:chemistry; D005618:Fresh Water / Q000032:analysis*; D014227:Triazines / Q000032:analysis*; D014873:Water Pollutants / Q000032:analysis
chemical_list: D001392:Azocines; D053834:Explosive Agents; D014227:Triazines; D014873:Water Pollutants; D002725:Chloroform; C007950:octogen; C009160:cyclonite