title: Using a patient image archive to diagnose retinopathy.
abstract: Diabetes has become an epidemic that is expected to impact 365 million people worldwide by 2025. Consequently, diabetic retinopathy is the leading cause of blindness in the industrialized world today. If detected early, treatments can preserve vision and significantly reduce debilitating blindness. Through this research we are developing and testing a method for automating the diagnosis of retinopathy in a screening environment using a patient archive and digital fundus imagery. We present an overview of our content-based image retrieval (CBIR) approach and provide performance results for a dataset of 98 images from a study in Canada when compared to an archive of 1,355 patients from a study in the Netherlands. An aggregate performance of 89% correct diagnosis is achieved, demonstrating the potential of automated, web-based diagnosis for a broad range of imagery collected under different conditions and with different cameras.
authors.affiliation: Image Science and Machine Vision Group at the Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6075, USA. tobinkwjr@ornl.gov
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Tobin
authors.forename: Michael D
authors.initials: MD
authors.lastname: Abramoff
authors.forename: Edward
authors.initials: E
authors.lastname: Chaum
authors.forename: Luca
authors.initials: L
authors.lastname: Giancardo
authors.forename: V
authors.initials: V
authors.lastname: Govindasamy
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Karnowski
authors.forename: Matthew T S
authors.initials: MT
authors.lastname: Tennant
authors.forename: Stephen
authors.initials: S
authors.lastname: Swainson
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003628:Database Management Systems; D003930:Diabetic Retinopathy / Q000473:pathology*; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008403:Mass Screening / Q000379:methods; D010363:Pattern Recognition, Automated / Q000379:methods*; D011873:Radiology Information Systems; D015203:Reproducibility of Results; D042262:Retinoscopy / Q000379:methods*; D012680:Sensitivity and Specificity