Predictors of successful early extubation following congenital cardiac surgery in neonates and infants.
BACKGROUND
There is a paucity of literature discussing the predictive likelihood of successfully extubating neonates and infants in the operating room immediately following congenital cardiac surgery. Given the unknown consequences of anaesthetics on neurodevelopmental outcomes, minimising the exposure of this population to such agents may have long-term benefits.


METHODS
Retrospective chart review of 391 patients less than 1 year of age.


RESULTS
The probability of successfully extubating these patients was based on quantifiable, objective criteria. The relevant variables include age, weight, bypass time, lactate level and specific congenital anomaly.


CONCLUSIONS
The practice of immediate extubation of infants and neonates is achievable, safe and predicted based on specific patient variables. This practice will minimise the anaesthetic exposure of these especially young patients who may be at risk for long-term consequences related to anaesthetic exposure.
Winch
Peter D
PD
Nationwide Children's Hospital, Department of Anesthesiology, Columbus, OH 43205, USA. Peter.Winch@Nationwidechildrens.org
Nicholson
Lisa
L
Isaacs
Janet
J
Spanos
Steven
S
Olshove
Vincent
V
Naguib
Aymen
A
D000367:Age Factors; D000758:Anesthesia; D001835:Body Weight; D006348:Cardiac Surgical Procedures; D006331:Heart Diseases / Q000151:congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D007902:Length of Stay; D016015:Logistic Models; D011182:Postoperative Care; D012189:Retrospective Studies; D016896:Treatment Outcome