title: Two new solanapyrone analogues from the endophytic fungus Nigrospora sp. YB-141 of Azadirachta indica.
abstract: Two new solanapyrone analogues, solanapyrones N and O (1 and 2, resp.), and three known compounds, solanapyrone C (3), nigrosporalactone (4), and phomalactone (5), were isolated from the fermentation culture of Nigrospora sp. YB-141, an endophytic fungus isolated from Azadirachta indica A. Juss. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. The antifungal activities of 1-5 towards seven phytopathogenic fungi were tested. Most of the compounds exhibited no or only weak antifungal activities.
authors.affiliation: Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, Yunnan, P. R. China. shwu123@126.com
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Wu
authors.forename: You-Wei
authors.initials: YW
authors.lastname: Chen
authors.forename: Shi-Cheng
authors.initials: SC
authors.lastname: Shao
authors.forename: Li-Dong
authors.initials: LD
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Yu
authors.forename: Zhi-Ying
authors.initials: ZY
authors.lastname: Li
authors.forename: Li-Yuan
authors.initials: LY
authors.lastname: Yang
authors.forename: Shao-Lan
authors.initials: SL
authors.lastname: Li
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D031601:Azadirachta / Q000382:microbiology*; D009682:Magnetic Resonance Spectroscopy; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D011753:Pyrones; C539329:solanapyrone N; C539330:solanapyrone O