An efficient and chemoselective synthesis of benzo[e][1,4]thiazepin-2(1H,3H,5H)-ones via a microwave-assisted multi-component reaction in water.
A new and efficient strategy for the synthesis of benzo[e][1,4]thiazepin-2(1H,3H,5H)-ones via a microwave-assisted multi-component reaction in aqueous media is described.
Tu
Shu-Jiang
SJ
School of Chemistry and Chemical Engineering, Xuzhou Normal University, Key Laboratory of Biotechnology for medicinal Plant, Xuzhou, Jiangsu, 211116, PR China. laotu@xznu.edu.cn
Cao
Xu-Dong
XD
Hao
Wen-Juan
WJ
Zhang
Xiao-Hong
XH
Yan
Shu
S
Wu
Shan-Shan
SS
Han
Zheng-Guo
ZG
Shi
Feng
F
D000447:Aldehydes / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry; D055772:Green Chemistry Technology; D008872:Microwaves; D013379:Substrate Specificity; D013696:Temperature; D013841:Thiazepines / Q000138:chemical synthesis* / Q000737:chemistry; D053778:Thiazolidines / Q000737:chemistry; D013864:Thioglycolates / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D000447:Aldehydes; D000814:Aniline Compounds; D013841:Thiazepines; D053778:Thiazolidines; D013864:Thioglycolates; D014867:Water; C017487:2-mercaptoacetate; C023650:aniline