title: Rubiacordone A: a new anthraquinone glycoside from the roots of Rubia cordifolia.
abstract: A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-alpha-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.
authors.affiliation: College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, PR China. drxiang@hotmail.com
authors.forename: Xiang
authors.initials: X
authors.lastname: Li
authors.forename: Zhi
authors.initials: Z
authors.lastname: Liu
authors.forename: Yun
authors.initials: Y
authors.lastname: Chen
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Wang
authors.forename: Yi-Nan
authors.initials: YN
authors.lastname: Zheng
authors.forename: Guang-Zhi
authors.initials: GZ
authors.lastname: Sun
authors.forename: Chang-Chun
authors.initials: CC
authors.lastname: Ruan
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D008516:Medicine, Chinese Traditional; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D045470:Rubia / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000880:Anthraquinones; D000890:Anti-Infective Agents; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010936:Plant Extracts