title: Family members of critically ill cancer patients: assessing the symptoms of anxiety and depression.
abstract: OBJECTIVE
  To determine prevalence and factors associated with symptoms of anxiety and depression in family members of critically ill cancer patients.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  A 23-bed intensive care unit in a tertiary cancer centre.
  
  
  METHODS
  Three hundred consecutive families of cancer patients with length of stay >72 h in ICU.
  
  
  METHODS
  None.
  
  
  RESULTS
  The Hospital Anxiety and Depression Scale questionnaire and critical care family needs inventory were completed by family members. Prevalence of anxiety and depression in family members was 71 and 50.3%, respectively. Regarding the patients' disease, family depression was correlated with presence of metastasis, whereas hematological malignancies correlated with family' anxiety. Anxiety was independently associated with one patient-related factor (prolonged mechanical ventilation) and two family-related factors (catholic religion and gender). Factors associated with symptoms of depression included one patient-related factor (presence of metastasis) and one family-related factor (gender).
  
  
  CONCLUSIONS
  Present findings demonstrated a high prevalence of anxiety and depression in critically ill cancer patients' family members during an intensive care unit stay.
authors.affiliation: Unidade de Terapia Intensiva, Centro de Tratamento e Pesquisa Hospital A C Camargo, Rua Prof. Antônio Prudente, 211, São Paulo, SP CEP 01509-900, Brazil.
authors.forename: Renata Rego Lins
authors.initials: RR
authors.lastname: Fumis
authors.forename: Daniel
authors.initials: D
authors.lastname: Deheinzelin
mesh_terms: D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis* / Q000209:etiology*; D015331:Cohort Studies; D016638:Critical Illness; D003866:Depressive Disorder / Q000175:diagnosis* / Q000209:etiology*; D005190:Family / Q000523:psychology*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology*; D015995:Prevalence; D011446:Prospective Studies; D012121:Respiration, Artificial / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires