Novel acylated lipo-oligosaccharides from the tubers of Ipomoea batatas.
Nine new lipo-oligosaccharides, batatosides H-P, were isolated from the tubers of Ipomoea batatas (Convolvulaceae). Spectral and chemical methods allowed to characterize them as tetra- or penta-saccharides that form a macrolactone with the aglycone, (11S)-hydroxyhexadecanoic acid (jalapinolic acid), the absolute configuration of which was established by Mosher's method. Batatosides L and O showed a weak inhibitory effect on the growth of Hep-2 cells, while the others proved to be inactive.
Yin
Yong-Qin
YQ
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, People's Republic of China.
Wang
Jun-Song
JS
Luo
Jian-Guang
JG
Kong
Ling-Yi
LY
D002240:Carbohydrate Sequence; D002460:Cell Line; D006801:Humans; D027723:Ipomoea batatas / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009844:Oligosaccharides / Q000737:chemistry*; D035281:Plant Tubers / Q000737:chemistry*
D008070:Lipopolysaccharides; D009844:Oligosaccharides