title: Extremely late drug-eluting stent thrombosis: 2037 days after deployment.
abstract: Thrombosis of drug eluting stents has been documented up to four years after stent implantation, often in the setting of cessation of antiplatelet therapy. We present a case of drug-eluting stent thrombosis, 2037 days after initial implantation, which we believe is the latest reported case. Late stent thrombosis remains a rare but catastrophic complication of coronary intervention. We hypothesize that the procoagulant milieu of surgery, coupled with cessation of one or both antiplatelet agents preoperatively, compounds the risk of perioperative stent thrombosis.
authors.affiliation: St Vincent's Hospital Melbourne, Fitzroy, VIC 3065, Australia. jamielayland@hotmail.com
authors.forename: Jamie
authors.initials: J
authors.lastname: Layland
authors.forename: Christine
authors.initials: C
authors.lastname: Jellis
authors.forename: Robert
authors.initials: R
authors.lastname: Whitbourn
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation; D000925:Anticoagulants / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000008:administration & dosage; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D054855:Drug-Eluting Stents; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D020123:Sirolimus / Q000008:administration & dosage; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D002317:Cardiovascular Agents; D010975:Platelet Aggregation Inhibitors; D020123:Sirolimus