title: [A medical and economic study about use of hemostatic glues in cardiac surgery].
abstract: BACKGROUND
  The impact of the use of biological and synthetic glues in cardiac surgery was assessed by an economic and medical study.
  
  
  METHODS
  The observational prospective study had duration of three months. All the patients undergoing cardiac surgery were included in the study. The end points were medical (blood transfusion) and economic (duration and cost of the stay in hospital). There were 2 groups: treated or not by glues.
  
  
  METHODS
  T Student tests.
  
  
  RESULTS
  Among 154 patients, the 2 principal indications were valvular replacement (48%) and coronary artery bypass grafting (37%). Fifty seven (37%) patients received a glue. The number of transfused globular units and the duration of the stay in the intensive care unit were significantly higher (p<0.05) by treated patients.
  
  
  CONCLUSIONS
  Not only the use of glues did not decrease the post-operative bleedings but it increased also the cost of the stay in hospital. Guidelines were validated by the hospital Commission on drugs.
authors.affiliation: Pharmacie du Groupe Hospitalier Sud, CHU Amiens, Salouel, France. sandra.ameslant@free.fr
authors.forename: Sandra
authors.initials: S
authors.lastname: Ameslant
authors.forename: Capuccine
authors.initials: C
authors.lastname: Delgove
authors.forename: Blaise
authors.initials: B
authors.lastname: Tramier
authors.forename: Halima
authors.initials: H
authors.lastname: Lescoat
authors.forename: Thierry
authors.initials: T
authors.lastname: Caus
authors.forename: Françoise
authors.initials: F
authors.lastname: Desablens
authors.forename: Abir
authors.initials: A
authors.lastname: Petit
mesh_terms: D000269:Adhesives / Q000191:economics* / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000191:economics* / Q000379:methods*; D005340:Fibrinogen / Q000191:economics / Q000627:therapeutic use; D005602:France; D005976:Glutaral / Q000191:economics / Q000627:therapeutic use; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008875:Middle Aged; D011446:Prospective Studies; D011506:Proteins / Q000191:economics / Q000627:therapeutic use; D013213:Starch / Q000191:economics / Q000627:therapeutic use
chemical_list: D000269:Adhesives; C527600:Arista; C472676:Bio-glue; D011506:Proteins; D005340:Fibrinogen; D013213:Starch; D005976:Glutaral