title: Near-IR remote release from assemblies of liposomes and nanoparticles.
abstract: Set free by light: Near-IR (NIR) laser-initiated remote release of fluorescent dye from complexes of liposome-gold-nanoparticle aggregates is demonstrated (see fluorescence images). Complexes of the desired size are shown to be a viable approach to the construction of vesicle-based drug-delivery systems with light-triggered remote release characteristics. This opens up a new method to manipulate liposome-based drug-delivery systems in a biocompatible way by using the near-IR spectral range.
authors.affiliation: Department of Interfaces, Max Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14424 Golm/Potsdam, Germany. dmitry.volodkin@mpikg.mpg.de
authors.forename: Dmitry V
authors.initials: DV
authors.lastname: Volodkin
authors.forename: Andre G
authors.initials: AG
authors.lastname: Skirtach
authors.forename: Helmuth
authors.initials: H
authors.lastname: Möhwald
mesh_terms: D004337:Drug Carriers / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry / Q000528:radiation effects; D006046:Gold / Q000737:chemistry*; D007834:Lasers; D008081:Liposomes / Q000737:chemistry* / Q000528:radiation effects; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission
chemical_list: D004337:Drug Carriers; D005456:Fluorescent Dyes; D008081:Liposomes; D006046:Gold