title: Adults with intellectual disabilities: prevalence, incidence and remission of aggressive behaviour and related factors.
abstract: BACKGROUND
  Aggressive behaviours can be disabling for adults with intellectual disabilities (ID), with negative consequences for the adult, their family and paid carers. It is surprising how little research has been conducted into the epidemiology of these needs, given the impact they can have. This study investigates point prevalence, 2-year incidence and 2-year remission rates for aggressive behaviour (physically aggressive, destructive and verbally aggressive), and it investigates which factors are independently associated with aggressive behaviour.
  
  
  METHODS
  All adults with ID - within a geographically defined area of Scotland, UK - were recruited to a longitudinal cohort. At baseline, assessments were undertaken of demography, lifestyle, supports, development, problem behaviours, disabilities and physical and mental health. These were repeated for a 2-year period.
  
  
  RESULTS
  At baseline, the participation rate was 1023 (65.5%). After 2 years, the cohort retention was 651 adults. The point prevalence of Diagnostic Criteria for Psychiatric Disorders for Use with Adults with Learning Disabilities/Mental Retardation (DC-LD) aggressive behaviour was 9.8% (95% confidence interval = 8.0-11.8%), 2-year incidence was 1.8%, and 2-year remission rate from all types of aggressive behaviour meeting DC-LD criteria was 27.7%. The factors independently associated with aggressive behaviours were lower ability, female gender, not living with a family carer, not having Down syndrome, having attention-deficit hyperactivity disorder and having urinary incontinence. Incidence of aggressive behaviour meeting DC-LD criteria in adult life is similar to that for each of psychotic, anxiety and organic disorders.
  
  
  CONCLUSIONS
  Aggressive behaviour is common among adults with ID, but contrary to previous suggestions, more than a quarter remit within the short to medium term. This is important knowledge for professionals as well as the person and her/his family and paid carers. There is much yet to learn about the mechanisms underpinning aetiology and maintenance of aggressive behaviour in this population, and exploratory epidemiological investigations such as this have a role to play in progressing research towards further hypothesis testing and trials to influence clinical practice, service development and policy.
authors.affiliation: Section of Psychological Medicine, Division of Community Based Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK. sacooper@clinmed.gla.ac.uk
authors.forename: S-A
authors.initials: SA
authors.lastname: Cooper
authors.forename: E
authors.initials: E
authors.lastname: Smiley
authors.forename: A
authors.initials: A
authors.lastname: Jackson
authors.forename: J
authors.initials: J
authors.lastname: Finlayson
authors.forename: L
authors.initials: L
authors.lastname: Allan
authors.forename: D
authors.initials: D
authors.lastname: Mantry
authors.forename: J
authors.initials: J
authors.lastname: Morrison
mesh_terms: D000203:Activities of Daily Living / Q000145:classification; D000293:Adolescent; D000328:Adult; D000374:Aggression / Q000523:psychology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000453:epidemiology / Q000523:psychology; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004314:Down Syndrome / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D015994:Incidence; D008607:Intellectual Disability / Q000453:epidemiology* / Q000523:psychology; D007360:Intelligence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012606:Scotland; D012737:Sex Factors; D012931:Social Environment; D014549:Urinary Incontinence / Q000523:psychology; D055815:Young Adult