title: Use of ecstasy and other psychoactive substances among school-attending adolescents in Taiwan: national surveys 2004-2006.
abstract: BACKGROUND
  With the backdrop of a global ecstasy epidemic, this study sought to examine the trend, correlates, and onset sequence of ecstasy use among adolescents in Taiwan, where a well-established gateway drug such as marijuana is much less popular.
  
  
  METHODS
  A multistage probability survey of school-attending adolescents in grades 7, 9, 10, and 12, aged 11-19 years, was conducted in 2004, 2005, and 2006. A self-administered anonymous questionnaire elicited response rates ranging from 94.3% to 96.6%. The sample sizes were 18232 respondents in 2004, 17986 in 2005, and 17864 in 2006.
  
  
  RESULTS
  In terms of lifetime prevalence and incidence, ecstasy and ketamine by and large appeared as the first and second commonly used illegal drugs, respectively, among middle (grades 7 and 9) and high school students (grades 10 and 12) during the 3-year survey period; however, this order was reversed in the middle school-aged students starting in 2006. Having sexual experience, tobacco use, and betel nut use were factors consistently associated with the onset of ecstasy use across years. The majority of ecstasy users had been involved in polydrug use, such as the use of ketamine (41.4%-53.5%), marijuana (12.7%-18.7%), and methamphetamine (4.2%-9.5%).
  
  
  CONCLUSIONS
  From 2004 to 2006, a decline was noted in the prevalence and incidence rate of ecstasy, a leading illegal drug used by school-attending adolescents in Taiwan since the early 2000s. The emerging ketamine use trend may warrant more attention in the future.
authors.affiliation: Institute of Epidemiology, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei 100, Taiwan, Republic of China. wjchen@ntu.edu.tw
authors.forename: Wei J
authors.initials: WJ
authors.lastname: Chen
authors.forename: Tsung-Chieh
authors.initials: TC
authors.lastname: Fu
authors.forename: Te-Tien
authors.initials: TT
authors.lastname: Ting
authors.forename: Wei-Lun
authors.initials: WL
authors.lastname: Huang
authors.forename: Guang-Mang
authors.initials: GM
authors.lastname: Tang
authors.forename: Chuhsing Kate
authors.initials: CK
authors.lastname: Hsiao
authors.forename: Chuan-Yu
authors.initials: CY
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D005260:Female; D006213:Hallucinogens / Q000009:adverse effects*; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects*; D016015:Logistic Models; D008297:Male; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects*; D016017:Odds Ratio; D015995:Prevalence; D011619:Psychotropic Drugs / Q000009:adverse effects; D018570:Risk Assessment; D012309:Risk-Taking; D017678:Sex Distribution; D013334:Students / Q000706:statistics & numerical data; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000209:etiology; D013624:Taiwan / Q000453:epidemiology
chemical_list: D006213:Hallucinogens; D013287:Illicit Drugs; D011619:Psychotropic Drugs; D018817:N-Methyl-3,4-methylenedioxyamphetamine