title: Non-traumatic rupture of spleen: can splenectomy be applied selectively?
abstract: BACKGROUND
  Non-traumatic rupture of the spleen is a rare condition. It can occur in a pathological spleen caused by any of a variety of diseases. For yet unknown reasons this condition may sometimes involve an apparently normal spleen as well.
  
  
  OBJECTIVE
  To examine the incidence, symptoms, causes, therapy and prognosis of "spontaneous" splenic rupture.
  
  
  METHODS
  We conducted a retrospective study of seven patients diagnosed with splenic rupture not related to any traumatic event, who had been treated in the surgical department of a community hospital within the last 19 years.
  
  
  RESULTS
  The male to female ratio was 5:2. In some patients, no background disease that could explain increased friability of splenic tissue could be identified. In some cases, where hemodynamic stability and absence of peritoneal signs afforded observation, splenectomy was delayed. In one case it was avoided altogether.
  
  
  CONCLUSIONS
  "Spontaneous" rupture of spleen should be suspected when abdominal symptomatology occurs against a background of an acute infectious disease, especially in young males, or a disease known to affect target organs of the reticular endothelial system. Preoperative use of imaging studies in hemodynamically stable patients can sometimes obviate surgery, or in cases of massive hemoperitoneum reduce intraoperative time.
authors.affiliation: Department of Surgery, Ziv Medical Center, Safed, Israel. amram.h@ziv.health.gov.il
authors.forename: Amram
authors.initials: A
authors.lastname: Hadary
authors.forename: Igor
authors.initials: I
authors.lastname: Dashkovsky
authors.forename: Arkady
authors.initials: A
authors.lastname: Rapaport
authors.forename: Juan C
authors.initials: JC
authors.lastname: Cozakov
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006465:Hemoperitoneum; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D013156:Splenectomy; D013161:Splenic Rupture / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology