title: [Physiopathologic aspects of microcirculation in intensive care].
abstract: In critical care patients, microvascular alterations and perfusion heterogeneity play an important role in the persistence of cellular hypoxia despite a satisfactory functioning of the macrocirculation. Advance in the knowledge of microcirculatory pathophysiology, and its relation with the macrocirculation could be in the future a way to improve the outcome of critically ill patients. Moreover, the evolution of clinical practice towards microcirculation monitoring as a standard of care, with new therapeutic targets aimed to increase tissue perfusion, could be a revolution in critical care practice.
authors.affiliation: Service des soins intensifs, HUG, 1211 Genève 14.
authors.forename: N
authors.initials: N
authors.lastname: Siegenthaler
authors.forename: R
authors.initials: R
authors.lastname: Giraud
authors.forename: J-A
authors.initials: JA
authors.lastname: Romand
authors.forename: K
authors.initials: K
authors.lastname: Bendjelid
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D003422:Critical Care / Q000592:standards*; D006439:Hemodynamics; D006801:Humans; D008833:Microcirculation; D008991:Monitoring, Physiologic; D010101:Oxygen Consumption; D012772:Shock, Septic / Q000503:physiopathology*