title: Survey of benzodiazepine and antidepressant use in outpatients with mood disorders in Japan.
abstract: Data on benzodiazepine use in mood disorders are still limited, especially among seniors. A cross-sectional review of psychotropic prescriptions in 948 outpatients with mood disorders (405 male; mean +/- SD age, 52 +/- 17 years; age range, 16- 91 years) was conducted in Japan. The use of benzodiazepine-derivative anxiolytics was approximately 60% in all decades, including older patients, without a group difference. The frequent use of benzodiazepines is a cause for concern because they are not preferred treatment, given their well-known adverse effects especially in the elderly.
authors.affiliation: Keio University, School of Medicine, Department of Neuropsychiatry, Tokyo, Japan. mcn41320@biglobe.ne.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Uchida
authors.forename: Takefumi
authors.initials: T
authors.lastname: Suzuki
authors.forename: David C
authors.initials: DC
authors.lastname: Mamo
authors.forename: Benoit H
authors.initials: BH
authors.lastname: Mulsant
authors.forename: Kenichi
authors.initials: K
authors.lastname: Tsunoda
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kikuchi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Nakajima
authors.forename: Kensuke
authors.initials: K
authors.lastname: Nomura
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tomita
authors.forename: Koichiro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Haruo
authors.initials: H
authors.lastname: Kashima
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004363:Drug Utilization; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D010045:Outpatients; D055815:Young Adult
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D001569:Benzodiazepines