New C(19)- and C(18)-diterpenoid alkaloids from Delphinium anthriscifolium var. savatieri.
Three new C(19)-diterpenoid alkaloids, anthriscifoldines A-C (1-3), and two new C(18)-diterpenoid alkaloids, anthriscifolcines F and G (5, 6), were obtained from the whole herbs of Delphinium anthriscifolium var. savatieri during our further investigation on a larger scale of recollected plants. Their structures were elucidated based on the interpretation of NMR and high-resolution ESI-MS data, and chemical transformation. In addition, five known C(19)-diterpenoid alkaloids were also isolated and identified as nudicaulamine (4), delbruninol (7), blacknine (8), winkleriline (9), and deltaline (10).
Song
Lei
L
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, P.R. China.
Liu
Xiao-Yu
XY
Chen
Qiao-Hong
QH
Wang
Feng-Peng
FP
D000470:Alkaloids / Q000737:chemistry*; D002236:Carbohydrate Conformation; D031882:Delphinium / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D021241:Spectrometry, Mass, Electrospray Ionization
D000470:Alkaloids; D004224:Diterpenes; C539043:anthriscifoldine A; C539044:anthriscifoldine B; C539045:anthriscifoldine C