title: Innovations in clinical trials informatics.
abstract: This paper will investigate innovations in information management for use in clinical trials. The application typifies a complex, adaptive, distributed and information-rich environment for which continuous innovation is necessary. Organisational innovation is highlighted as well as the technical innovations in workflow processes and their representation as an integrated set of web services. Benefits realization uncovers further innovations in the business strand of the work undertaken. Following the description of the development of this information management system, the semantic web is postulated as a possible solution to tame the complexity related to information management issues found within clinical trials support systems.
authors.affiliation: Department of Information Science, Loughborough University, Loughborough, UK. R.Summers@lboro.ac.uk
authors.forename: Ron
authors.initials: R
authors.lastname: Summers
authors.forename: Hiten
authors.initials: H
authors.lastname: Vyas
authors.forename: Nilesh
authors.initials: N
authors.lastname: Dudhal
authors.forename: Neil F
authors.initials: NF
authors.lastname: Doherty
authors.forename: Crispin R
authors.initials: CR
authors.lastname: Coombs
authors.forename: Mark
authors.initials: M
authors.lastname: Hepworth
mesh_terms: D001185:Artificial Intelligence; D002986:Clinical Trials as Topic; D003195:Computer Communication Networks; D003201:Computers; D003628:Database Management Systems; D001330:Electronic Data Processing; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D007256:Information Systems; D008490:Medical Informatics; D008492:Medical Informatics Computing; D017146:Models, Organizational; D009936:Organizational Innovation; D018511:Systems Integration; D014584:User-Computer Interface