A non-invasive assessment for endothelial function of small animals.
At present, many studies indicate that atherosclerosis has high correlation with risk factors of cardiovascular diseases. Furthermore, atherosclerosis usually accompanies with endothelial dysfunction. However, endothelial dysfunction dose not necessarily have situation of atherosclerosis. It means that endothelial dysfunction can be the early change of atherosclerosis. If we can use non-invasive methods to monitor the function of vascular endothelia, it will be very helpful for early assessment of atherosclerosis. It can also detect atherosclerosis earlier then decrease the mortality and mobility of atherosclerosis related diseases, such as coronary artery disease, stroke and chronic renal disease, with appropriate management.
Wu
Hsien-Tsai
HT
Department of Electrical Engineering, National Dong Hwa University, Hualien, Taiwan. dsphans@mail.ndhu.edu.tw
Yang
Chun-Cheng
CC
Liu
An-Bang
AB
Wang
Chien-Hsing
CH
D000465:Algorithms; D000818:Animals; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D004730:Endothelium, Vascular / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods*; D010108:Oxyhemoglobins / Q000032:analysis*; D051381:Rats; D011921:Rats, Inbred WKY; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014664:Vasodilation / Q000502:physiology*
D010108:Oxyhemoglobins