title: Discordance between Staphylococcus aureus nasal colonization and skin infections in children.
abstract: We examined nasal carriage of Staphylococcus aureus in otherwise healthy children presenting with skin and soft tissue infections. We found high rates of nasal colonization with S. aureus, but significant discordance between nasal and wound isolates. Recurrent skin and soft tissue infections were common but unrelated to baseline methicillin-resistant S. aureus nasal colonization status.
authors.affiliation: Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA. achen33@jhmi.edu
authors.forename: Aaron E
authors.initials: AE
authors.lastname: Chen
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Cantey
authors.forename: Karen C
authors.initials: KC
authors.lastname: Carroll
authors.forename: Tracy
authors.initials: T
authors.lastname: Ross
authors.forename: Sharon
authors.initials: S
authors.lastname: Speser
authors.forename: George K
authors.initials: GK
authors.lastname: Siberry
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D007223:Infant; D008712:Methicillin / Q000494:pharmacology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D009296:Nasal Cavity / Q000382:microbiology*; D018461:Soft Tissue Infections / Q000453:epidemiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013207:Staphylococcal Skin Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D014946:Wound Infection / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D008712:Methicillin