title: A computer simulation of clinical Electrophysiological Study.
abstract: We present a computer simulation of Electrophysiological Study (EPS) using a heart model. In this simulation, standard pacing protocols as used in the clinical EPS, including the atrial extrastimulation, ventricular extrastimulation, incremental atrial pacing, and incremental ventricular pacing, were developed in the heart model. The corresponding excitation and propagation process of the heart, and the intracardiac electrograms that would be measured with catheter electrodes were computed. We successfully reproduced the EPS tests with the heart model. Typical results included the determination of the refractory period, induction and termination of supraventricular tachycardias, and the localization of accessory pathway by using the heart model of the Wolff-Parkinson-White (WPW) syndrome of type A. We believe this study shows one of the latest progresses in application of whole-heart modeling and computer simulation of electrocardiology.
authors.affiliation: Biomedical Information Technology Laboratory, University of Aizu, Aizu-Wakamatsu, Fukushima 965-8580, Japan. zhuxin@u-aizu.ac.jp
authors.forename: Xin
authors.initials: X
authors.lastname: Zhu
authors.forename: Daming
authors.initials: D
authors.lastname: Wei
mesh_terms: D000200:Action Potentials; D018780:Body Surface Potential Mapping / Q000379:methods*; D002304:Cardiac Pacing, Artificial / Q000379:methods; D003198:Computer Simulation; D022062:Electrophysiologic Techniques, Cardiac / Q000379:methods*; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular; D014927:Wolff-Parkinson-White Syndrome / Q000175:diagnosis* / Q000503:physiopathology*