title: Subendomyocardial perfusion abnormality and necrosis detected by magnetic resonance imaging in a patient with isolated noncompaction of the ventricular myocardium associated with ventricular tachycardia.
abstract: A 74-year-old man presented with left ventricular failure and nonsustained ventricular tachycardia. Coronary angiography revealed normal coronary arteries; left ventriculography showed hypokinesis of the lateral wall segment. The ejection fraction was 54%. Cine-magnetic resonance imaging showed a double-layered appearance on four-chamber view and marked trabeculations as well as intratrabecular recesses in the inferolateral segments on short-axis view, findings consistent with isolated noncompaction of the ventricular myocardium (INVM). Contrast-enhanced imaging revealed hypoperfusion and delayed enhancement of the endomyocardium in the inferolateral segments. Subendomyocardial perfusion abnormality and necrosis may constitute the diagnostic criteria of INVM.
authors.affiliation: Department of Cardiology, Nihon University School of Medicine, 1-8-13 Kanda-Surugadai, Chiyoda-ku, Tokyo, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Sato
authors.forename: Naoya
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Shinro
authors.initials: S
authors.lastname: Matsuo
authors.forename: Shinobu
authors.initials: S
authors.lastname: Imai
authors.forename: Shunichi
authors.initials: S
authors.lastname: Yoda
authors.forename: Shigemasa
authors.initials: S
authors.lastname: Tani
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kasamaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kunimoto
authors.forename: Motoichiro
authors.initials: M
authors.lastname: Takahashi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saito
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D003326:Coronary Circulation; D004562:Electrocardiography; D006330:Heart Defects, Congenital / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006352:Heart Ventricles / Q000002:abnormalities / Q000503:physiopathology; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D055414:Myocardial Perfusion Imaging; D009206:Myocardium / Q000473:pathology*; D013318:Stroke Volume; D017180:Tachycardia, Ventricular / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone