title: Rotational vs. standard coronary angiography: an image content analysis.
abstract: OBJECTIVE
  To evaluate the clinical utility of images acquired from rotational coronary angiographic (RA) acquisitions compared to standard "fixed" coronary angiography (SA).
  
  
  BACKGROUND
  RA is a novel angiographic modality that has been enabled by new gantry systems that allow calibrated automatic angiographic rotations and has been shown to reduce radiation and contrast exposure compared to SA. RA provides a dynamic multiple-angle perspective of the coronaries during a single contrast injection.
  
  
  METHODS
  The screening adequacy, lesion assessment, and a quantitative coronary analysis (QCA) of both SA and RA were compared by independent blinded review in 100 patients with coronary artery disease (CAD).
  
  
  RESULTS
  SA and RA recognize a similar total number of lesions (P = 0.61). The qualitative assessment of lesion characteristics and severity between modalities was comparable and lead to similar clinical decisions. Visualization of several vessel segments (diagonal, distal RCA, postero-lateral branches and posterior-descending) was superior with RA when compared to SA (P < 0.05). A QCA comparison (MLD, MLA, LL, % DS) revealed no difference between SA and RA. The volume of contrast (23.5 +/- 3.1 mL vs. 39.4 +/- 4.1; P = 0.0001), total radiation exposure (27.1 +/- 4 vs. 32.1 +/- 3.8 Gycm(2); P = 0.002) and image acquisition time (54.3 +/- 36.8 vs. 77.67 +/- 49.64 sec; P = 0.003) all favored RA.
  
  
  CONCLUSIONS
  Coronary lesion assessment, coronary screening adequacy, and QCA evaluations are comparable in SA and RA acquisition modalities in the diagnosis of CAD however RA decreases contrast volume, image acquisition time, and radiation exposure.
authors.affiliation: Division of Cardiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.
authors.forename: Joel A
authors.initials: JA
authors.lastname: Garcia
authors.forename: Pierfrancesco
authors.initials: P
authors.lastname: Agostoni
authors.forename: Nathan E
authors.initials: NE
authors.lastname: Green
authors.forename: James T
authors.initials: JT
authors.lastname: Maddux
authors.forename: S-Y James
authors.initials: SY
authors.lastname: Chen
authors.forename: John C
authors.initials: JC
authors.lastname: Messenger
authors.forename: Ivan P
authors.initials: IP
authors.lastname: Casserly
authors.forename: Adam
authors.initials: A
authors.lastname: Hansgen
authors.forename: Onno
authors.initials: O
authors.lastname: Wink
authors.forename: Babak
authors.initials: B
authors.lastname: Movassaghi
authors.forename: Bertron M
authors.initials: BM
authors.lastname: Groves
authors.forename: Paul
authors.initials: P
authors.lastname: Van Den Heuvel
authors.forename: Stefan
authors.initials: S
authors.lastname: Verheye
authors.forename: Glenn
authors.initials: G
authors.lastname: Van Langenhove
authors.forename: Paul
authors.initials: P
authors.lastname: Vermeersch
authors.forename: Frank
authors.initials: F
authors.lastname: Van den Branden
authors.forename: Yerem
authors.initials: Y
authors.lastname: Yeghiazarians
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Michaels
authors.forename: John D
authors.initials: JD
authors.lastname: Carroll
mesh_terms: D000368:Aged; D002932:Cineangiography; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D005060:Europe; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D012399:Rotation; D013997:Time Factors; D014481:United States
chemical_list: D003287:Contrast Media