title: Down syndrome screening: determining the cutoff level of risk for invasive testing.
authors.forename: P C J I
authors.initials: PC
authors.lastname: Schielen
authors.forename: H I J
authors.initials: HI
authors.lastname: Wildschut
authors.forename: J G
authors.initials: JG
authors.lastname: Loeber
mesh_terms: D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000009:adverse effects / Q000379:methods; D009426:Netherlands; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000009:adverse effects / Q000379:methods*; D012372:ROC Curve; D018570:Risk Assessment