An unusual radiologic pattern of cryptogenic organizing pneumonia: diffuse pulmonary nodules in a leukemia patient.
The radiological appearance of diffuse discrete pulmonary nodules associated with cryptogenic organizing pneumonia (COP) has been rarely described. We describe a case of COP in 49-year-old woman with acute myeloid leukemia who developed diffuse pulmonary nodules during the second course of induction chemotherapy. The clinical status of the patient and imaging findings suggested the presence of a pulmonary metastasis or infectious disease. A video-assisted thoracoscopic lung biopsy resulted in the unexpected diagnosis of COP as an isolated entity. Steroid therapy led to dramatic improvement of the clinical symptoms and the pulmonary lesions.
Ko
Kai Hsiung
KH
Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taiwan.
Hsu
Hsian He
HH
Kao
Woei Yau
WY
Chang
Ching Feng
CF
Cheng
Ming Fang
MF
Huang
Guo Shu
GS
D018549:Cryptogenic Organizing Pneumonia / Q000150:complications / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000473:pathology; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008875:Middle Aged; D055613:Multiple Pulmonary Nodules / Q000150:complications / Q000000981:diagnostic imaging*; D011859:Radiography