title: First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group.
abstract: BACKGROUND
  Little is known about first-episode drug-induced psychosis (F19.5).
  
  
  OBJECTIVE
  To examine the incidence, course, diagnostic stability, and outcomes of first-episode drug-induced psychosis (F19.5), and compare with first-episode schizophrenia (F20-21).
  
  
  METHODS
  An observational database was set up on all patients aged 16 and over with a first episode psychosis living in a county in Northern England between October 1998 and October 2005. Data were collected at presentation and annual follow-up. Information on patients with an ICD-10 diagnosis of either drug-induced psychosis (F19.5) or schizophrenia (F20) was compared.
  
  
  RESULTS
  There was no significant difference between the two groups in levels of hospitalisation and violence. Patients with a drug-induced psychosis were more likely to lose contact with services, and a third developed a schizophrenia-spectrum disorder.
  
  
  CONCLUSIONS
  Increased attention should be paid to maintaining engagement with this high-risk group who have a high rate of transition to schizophrenia.
authors.affiliation: Northumberland, Tyne and Wear NHS Trust, Northumberland, UK.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Crebbin
authors.forename: Emma
authors.initials: E
authors.lastname: Mitford
authors.forename: Roger
authors.initials: R
authors.lastname: Paxton
authors.forename: Douglas
authors.initials: D
authors.lastname: Turkington
mesh_terms: D000328:Adult; D002391:Catchment Area, Health / Q000706:statistics & numerical data; D015897:Comorbidity; D004739:England / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006296:Health Services / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D038801:International Classification of Diseases; D008137:Longitudinal Studies; D008297:Male; D002189:Marijuana Abuse / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011569:Psychiatric Status Rating Scales; D011605:Psychoses, Substance-Induced / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D011618:Psychotic Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D014754:Violence / Q000523:psychology / Q000706:statistics & numerical data