First total synthesis of (-)-caulerpenynol.
The first diastereoselective synthesis of the antimicrobial and cytotoxic agent (-)-caulerpenynol has been achieved in relatively few steps from the commercially available (S)-malic acid.
Commeiras
Laurent
L
Aix-Marseille Université, Institut des Sciences Moléculaires de Marseille iSm2, UMR 6263, équipe STeRéO, Campus Scientifique de Saint Jérôme, service 532, 13397, Marseille cedex 20, France. laurent.commeiras@univ-cezanne.fr
Thibonnet
Jérôme
J
Parrain
Jean-Luc
JL
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D002070:Butadienes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000480:Alkynes; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D002070:Butadienes; C538951:caulerpenynol