Disseminated Geosmithia argillacea infection in a German shepherd dog.
We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.
Grant
David C
DC
Department of Small Animal Clinical Sciences, Virginia Tech, Blacksburg. VA, USA. dgrant@vt.edu
Sutton
Deanna A
DA
Sandberg
Christina A
CA
Tyler
Ronald D
RD
Thompson
Elizabeth H
EH
Romanelli
Anna M
AM
Wickes
Brian L
BL
D000818:Animals; D004283:Dog Diseases / Q000382:microbiology / Q000473:pathology; D004285:Dogs; D005260:Female; D007668:Kidney / Q000473:pathology; D009181:Mycoses / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D013166:Spondylitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D032901:Talaromyces / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D013904:Thoracic Vertebrae / Q000382:microbiology / Q000473:pathology; D014556:Urine / Q000382:microbiology