Iridium-catalyzed reactions of trifluoromethylated compounds with alkenes: a C(sp3)-H bond activation alpha to the trifluoromethyl group.
Catalytic convenience: The use of iridium or ruthenium catalysts for C(sp(3))-H bond activation has led to the addition reaction of trifluoromethylated compounds to alkenes (see scheme). This atom-economical reaction occurs under neutral reaction conditions and without the formation of undesired defluorinated by-products, even at high temperature.
Guo
Yong
Y
Department of Chemistry, Okayama University of Science, 1-1, Ridai-cho, Okayama 700-0005, Japan.
Zhao
Xiaoming
X
Zhao
Xiaming
X
Zhang
Dazhi
D
Murahashi
Shun-ichi
S
D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry
D000475:Alkenes; D006845:Hydrocarbons, Fluorinated; D007495:Iridium; D002244:Carbon; D012428:Ruthenium; D006859:Hydrogen