Hearing loss in a woman on aspirin: the silent pharmacokinetic parameter.
A sudden hearing loss in a woman on aspirin has uncovered a frequently neglected toxicological parameter.
Koren
Gideon
G
From the Division of Clinical Pharmacology & Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada. gkoren@sickkids.ca
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000097:blood* / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects* / Q000097:blood* / Q000627:therapeutic use; D018450:Disease Progression; D005260:Female; D034381:Hearing Loss / Q000139:chemically induced*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D011507:Proteinuria / Q000378:metabolism; D012459:Salicylates / Q000097:blood; D014012:Tinnitus / Q000209:etiology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates; D001241:Aspirin