[Blood pressure and type 2 diabetes mellitus: impact of the insulin therapy].
BACKGROUND
The incidence of arterial hypertension is by 2-3 times with diabetics than with non-diabetics. Etiopathogenesis of arterial hypertension in type 2 diabetes is multifactorial insulin-resistance, obesity, hyperlipoproteinemia, age, smoking and probably method of treatment (insulin therapy). The aim of this retrospective study is to evaluate, over 5 years period, the level of blood pressure and the frequency's progression of arterial hypertension in 35 type 2 diabetes patients treated with insulin


METHODS
comparison of 35 type 2 diabetes patients treated with insulin to 35 controls treated with oral hypoglycemic agents.


RESULTS
No significant differences were found over 5 years period in mean systolic blood pressure, mean diastolic blood pressure and frequency of arterial hypertension. However, frequency of arterial hypertension was correlated with mean dose of insulin.


CONCLUSIONS
Our study confirms the long-term results found in the literature reading effects of insulin therapy on blood pressure in diabetic patients.
Dakhli
Saber
S
1 - service de diététique thérapeutique et des maladies de la nutrition, Institut National de Nutrition, Tunis, Tunisie
Lamine
Souhaib
S
Lamine
Faiza
F
Trabelsi
Nabil
N
Aouididi
Faten
F
Zouaoui
Chadia
C
Mami
Faika Ben
FB
Achour
Ahmed
A
D000284:Administration, Oral; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007279:Injections, Subcutaneous; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008687:Metformin / Q000008:administration & dosage; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013453:Sulfonylurea Compounds / Q000008:administration & dosage; D013997:Time Factors; D016896:Treatment Outcome
D007004:Hypoglycemic Agents; D007328:Insulin; D013453:Sulfonylurea Compounds; D008687:Metformin