[Atypical ductal hyperplasia and atypical epithelial proliferation of ductal type].
The definition of atypical ductal hyperplasia (ADH) encompasses qualitative and quantitative criteria. Qualitative criteria include cytological and architectural features similar to those of low grade ductal carcinoma in situ (DCIS), the quantitative criteria are characterized by metric features (2 mm or 2 ductules) or by the confines of lobules. In this article we discuss the morphology of ADH, the status of ADH in the low grade pathway of breast carcinoma development and its clinical significance. Furthermore, we comment some special forms of atypical epithelial proliferations of the ductal type.
Böcker
W
W
Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Domagk-Str. 17, 48159, Münster, Deutschland. werner.boecker@ukmuenster.de
Hungermann
D
D
Weigel
S
S
Roterberg
K
K
Decker
T
T
D001706:Biopsy; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology*; D002278:Carcinoma in Situ / Q000235:genetics / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000235:genetics / Q000473:pathology*; D002455:Cell Division; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007633:Keratins / Q000235:genetics; D019656:Loss of Heterozygosity
D007633:Keratins