title: Chemotherapy side-effect management using mobile phones.
abstract: Colorectal cancer is a major health problem in developed countries, accounting for a significant proportion of deaths in the population. Advances in chemotherapy treatment have led to therapy being delivered in the home-setting, which presents challenges in ensuring that treatment-related side-effects are detected and reported to clinical staff in an appropriate time-frame. A telemedicine system has been developed using a mobile-phone platform to allow patients to complete symptom diaries which trigger alerts paged to their nurse in the event of severe side-effects. Six patients used this system for two cycles of oral chemotherapy. Two cases of moderate symptoms deteriorating to more severe conditions were observed, and individual self-care and treatment advice were presented to these patients.
authors.affiliation: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, OX3 7DQ, UK.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Larsen
authors.forename: Joanna
authors.initials: J
authors.lastname: Rowntree
authors.forename: Annie M
authors.initials: AM
authors.lastname: Young
authors.forename: Sarah
authors.initials: S
authors.lastname: Pearson
authors.forename: Justine
authors.initials: J
authors.lastname: Smith
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Gibson
authors.forename: Andrew
authors.initials: A
authors.lastname: Weaver
authors.forename: Lionel
authors.initials: L
authors.lastname: Tarassenko
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000458:organization & administration*; D000368:Aged; D000069287:Capecitabine; D040421:Cell Phone; D003110:Colonic Neoplasms / Q000150:complications / Q000188:drug therapy*; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D004739:England; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D019114:Remote Consultation / Q000379:methods*
chemical_list: D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil