title: Development of flexible microelectrode arrays for recording cortical surface field potentials.
abstract: The fabrication, characterization and application of an 8-channel flexible microelectrode array for recording cortical surface field potentials is described. Polyimide-based microelectrode arrays were fabricated by using photolithography and physical vapour deposition (PVD) methods. Polyimide was chosen as the substrate and insulation material due to its suitable mechanical properties and biocompatibility. Electrodes and transmission lines were formed by sputter-coating of platinum thin films. Microelectrode arrays were characterized and tested successfully in vitro by impedance spectroscopy and in vivo by somatosensory evoked potential (SEP) recordings in rats. These tests indicated good performance and the potential of microelectrode arrays.
authors.affiliation: Department of Physics, University of Kuopio, Finland. sami.myllymaa@uku.fi
authors.forename: Sami
authors.initials: S
authors.lastname: Myllymaa
authors.forename: Katja
authors.initials: K
authors.lastname: Myllymaa
authors.forename: Hannu
authors.initials: H
authors.lastname: Korhonen
authors.forename: Irina
authors.initials: I
authors.lastname: Gureviciene
authors.forename: Kaj
authors.initials: K
authors.lastname: Djupsund
authors.forename: Heikki
authors.initials: H
authors.lastname: Tanila
authors.forename: Reijo
authors.initials: R
authors.lastname: Lappalainen
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000465:Algorithms; D000818:Animals; D002540:Cerebral Cortex / Q000473:pathology; D017097:Electric Impedance; D004566:Electrodes; D004594:Electrophysiology / Q000295:instrumentation* / Q000379:methods*; D005073:Evoked Potentials, Somatosensory; D008422:Materials Testing; D008839:Microelectrodes; D010984:Platinum / Q000737:chemistry; D051381:Rats; D013057:Spectrum Analysis / Q000379:methods; D013314:Stress, Mechanical; D014025:Titanium / Q000737:chemistry
chemical_list: D010984:Platinum; D014025:Titanium