title: [Studies on the anti-tumor activity principles of a marine-derived fungus BZYT-21].
abstract: OBJECTIVE
  To study the chemical constituents of a marine-derived fungus possessing anti-tumor activity.
  
  
  METHODS
  The compounds were isolated by various chromatographic methods and their structures were elucidated through spectroscopic analysis and chemical and physical properties.
  
  
  RESULTS
  Nine compounds were isolated and identified as: (S)-(-)-N-benzoylphenylalaninol, asperphnamate, cerevisterol, (22E, 24R)-6beta-methnoxyergosta-7,22-diene-3beta, 5alpha-diol, (22E, 24R)-5alpha, 6alpha-epoxy-ergosta-8, 22-diene-3beta, 7alpha-diol, (22E, 24R) -3beta, 5alpha, 9alpha-trihydroxyergosta-7, 22-diene-6-one, (22E, 24R) -3beta-hydroxy-ergosta-5, 8, 22-trien-7-one, ergosterol, ergosterol peroxide.
  
  
  CONCLUSIONS
  (22E, 24R)-3beta-hydroxy-ergosta-5, 8, 22-trien-7-one is isolated from microorganisms for the first time.
authors.affiliation: Department of Chemistry, Binzhou Medical Collage, Yantai 264003, China. gzh3308@163.com
authors.forename: Zong-Hua
authors.initials: ZH
authors.lastname: Gao
authors.forename: Li-Ying
authors.initials: LY
authors.lastname: Ma
authors.forename: Yun-Xiu
authors.initials: YX
authors.lastname: Shen
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000577:Amides / Q000737:chemistry / Q000302:isolation & purification*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification*; D004875:Ergosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D005658:Fungi / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008386:Marine Biology; D015394:Molecular Structure; D025282:Mycelium / Q000737:chemistry; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000470:Alkaloids; D000577:Amides; D000970:Antineoplastic Agents; D010840:Phytosterols; C006954:cerevisterol; C036071:ergosterol-5,8-peroxide; D004875:Ergosterol