Control of duplex formation and columnar self-assembly with heterogeneous amide/urea macrocycles.
The perfect blend: A new class of self-assembling cyclooligomers with mixed urea/amide backbone is described (see figure). A high level of hierarchical and directional control is achieved: depending on the level of backbone preorganization, columnar or tubular arrangements with either parallel or antiparallel growing modes can be selected.
Fischer
Lucile
L
CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunologie et Chimie Thérapeutiques, 15 rue René Descartes, 67000 Strasbourg, France.
Decossas
Marion
M
Briand
Jean-Paul
JP
Didierjean
Claude
C
Guichard
Gilles
G
D000577:Amides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D019281:Dimerization; D047028:Macrocyclic Compounds / Q000737:chemistry; D043942:Nanotubes / Q000737:chemistry; D014508:Urea / Q000737:chemistry*
D000577:Amides; D047028:Macrocyclic Compounds; D014508:Urea