title: Hydrodynamic properties of cyclodextrin molecules in dilute solutions.
abstract: Three well-known representatives of the cyclodextrin family were completely characterized by molecular hydrodynamics methods in three different solvents. For the first time the possibility of an estimation of velocity sedimentation coefficients s between 0.15 and 0.5 S by the numerical solution of the Lamm equation is shown. Comparison of the experimental hydrodynamic characteristics of the cyclodextrins with theoretical calculations for toroidal molecules allows an estimation of the thickness of the solvent layers on the surface of cyclodextrin molecules.
authors.affiliation: Laboratory of Macromolecular Chemistry and Nanoscience, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands. g.m.pavlov@tue.nl
authors.forename: Georges M
authors.initials: GM
authors.lastname: Pavlov
authors.forename: Evguenia V
authors.initials: EV
authors.lastname: Korneeva
authors.forename: Natalia A
authors.initials: NA
authors.lastname: Smolina
authors.forename: Ulrich S
authors.initials: US
authors.lastname: Schubert
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004058:Diffusion; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D004126:Dimethylformamide / Q000737:chemistry; D008956:Models, Chemical; D008958:Models, Molecular; D012984:Software; D012996:Solutions; D012997:Solvents / Q000737:chemistry; D013997:Time Factors; D014867:Water / Q000737:chemistry; D047391:alpha-Cyclodextrins / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*; D047408:gamma-Cyclodextrins / Q000737:chemistry*
chemical_list: D012996:Solutions; D012997:Solvents; D047391:alpha-Cyclodextrins; D047392:beta-Cyclodextrins; D047408:gamma-Cyclodextrins; D014867:Water; D004126:Dimethylformamide; D004121:Dimethyl Sulfoxide