Late vitamin K deficiency bleeding after intramuscular prophylaxis at birth: a case report.
We report the case of a 6-week-old female who presented an intracranial hemorrhage due to late vitamin K deficiency bleeding (VKDB). No other evident bleeding sites were present at the moment of diagnosis. Intramuscular vitamin K (1 mg) was administered at birth. She was exclusively breast-fed. No other risk factors for VKDB were detected. Low levels of vitamin K-dependent coagulation factors and their normalization after vitamin K administration confirmed the diagnosis of late VKDB. The present case suggests potential risks related to a single dose of intramuscular vitamin K at birth.
Ciantelli
M
M
Division of Neonatology, University of Pisa, Pisa, Italy. m.ciantelli@libero.it
Bartalena
L
L
Bernardini
M
M
Biver
P
P
Chesi
F
F
Boldrini
A
A
Sigali
E
E
D017668:Age of Onset; D000933:Antifibrinolytic Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D020300:Intracranial Hemorrhages / Q000209:etiology*; D016896:Treatment Outcome; D014812:Vitamin K / Q000008:administration & dosage*; D014813:Vitamin K Deficiency / Q000150:complications*
D000933:Antifibrinolytic Agents; D014812:Vitamin K