First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group.
BACKGROUND
Little is known about first-episode drug-induced psychosis (F19.5).


OBJECTIVE
To examine the incidence, course, diagnostic stability, and outcomes of first-episode drug-induced psychosis (F19.5), and compare with first-episode schizophrenia (F20-21).


METHODS
An observational database was set up on all patients aged 16 and over with a first episode psychosis living in a county in Northern England between October 1998 and October 2005. Data were collected at presentation and annual follow-up. Information on patients with an ICD-10 diagnosis of either drug-induced psychosis (F19.5) or schizophrenia (F20) was compared.


RESULTS
There was no significant difference between the two groups in levels of hospitalisation and violence. Patients with a drug-induced psychosis were more likely to lose contact with services, and a third developed a schizophrenia-spectrum disorder.


CONCLUSIONS
Increased attention should be paid to maintaining engagement with this high-risk group who have a high rate of transition to schizophrenia.
Crebbin
Kathleen
K
Northumberland, Tyne and Wear NHS Trust, Northumberland, UK.
Mitford
Emma
E
Paxton
Roger
R
Turkington
Douglas
D
D000328:Adult; D002391:Catchment Area, Health / Q000706:statistics & numerical data; D015897:Comorbidity; D004739:England / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006296:Health Services / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D038801:International Classification of Diseases; D008137:Longitudinal Studies; D008297:Male; D002189:Marijuana Abuse / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011569:Psychiatric Status Rating Scales; D011605:Psychoses, Substance-Induced / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D011618:Psychotic Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D014754:Violence / Q000523:psychology / Q000706:statistics & numerical data