title: Organocatalytic asymmetric alkylation of aldehydes by S(N)1-type reaction of alcohols.
abstract: Work-alcoholic! The elusive enantioselective catalytic alpha-alkylation of aldehydes, a widely sought transformation, was brought to execution by the use of alcohols capable of forming stabilized carbocations (see scheme, TFA = trifluoroacetic acid).
authors.affiliation: Dipartimento di Chimica G. Ciamician, Alma Mater Studiorum Università di Bologna, Via Selmi 2, 40126, Italy. piergiorgio.cozzi@unibo.it
authors.forename: Pier Giorgio
authors.initials: PG
authors.lastname: Cozzi
authors.forename: Fides
authors.initials: F
authors.lastname: Benfatti
authors.forename: Luca
authors.initials: L
authors.lastname: Zoli