Neonatal hypoglycemia in term, nondiabetic pregnancies.
OBJECTIVE
To define the incidence of hypoglycemia and identify risk factors in neonates from term, singleton, nondiabetic pregnancies.


METHODS
We conducted a matched case-control study of term, singleton infants weighing more than 2500 g in nondiabetic pregnancies. Cases with hypoglycemia (glucose < 50 mg/dL) were identified by International Classification of Diseases, ninth revision, codes. Two controls per case were matched on race, maternal age, and birthweight. Conditional logistic regression analyses were performed.


RESULTS
There were 116 cases and 232 controls studied. The incidence density of neonatal hypoglycemia was 24.7 per 1000 infant-days at risk. Hypoglycemia was less commonly associated with later gestational age (odds ratio [OR], 0.66; 95% confidence interval [CI], 0.53-0.85 per week of gestation). Maternal fever during labor was more common with hypoglycemia (OR, 4.08; 95% CI, 1.39-11.79). Public insurance was more than twice as common with hypoglycemia compared with those privately insured (OR, 2.31; 95% CI, 1.17-4.58).


CONCLUSIONS
Neonatal hypoglycemia was associated with earlier gestational age, intrapartum fever, and public insurance.
DePuy
Amy M
AM
Department of Obstetrics and Gynecology, Lehigh Valley Hospital and Health Network, Allentown, PA 18105, USA. Amy_M.DePuy@lvh.com
Coassolo
Kara M
KM
Som
Dara A
DA
Smulian
John C
JC
D000328:Adult; D001786:Blood Glucose; D016022:Case-Control Studies; D016640:Diabetes, Gestational / Q000453:epidemiology; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology*; D015994:Incidence; D007231:Infant, Newborn; D016015:Logistic Models; D011247:Pregnancy; D015995:Prevalence; D012307:Risk Factors; D047929:Term Birth; D055815:Young Adult
D001786:Blood Glucose