title: Can cetuximab affect paraneoplastic myopathy?
abstract: Cetuximab given concurrently with chemotherapy has shown survival benefit for patients with metastatic colon cancer. We report a case of a patient with metastatic colon cancer who developed paraneoplastic necrotizing myopathy that possibly responded to cetuximab despite lack of improvement of the underlying cancer.
authors.affiliation: Second Oncology Department, Metropolitan Hospital, Athens, Greece.
authors.forename: Eleni
authors.initials: E
authors.lastname: Galani
authors.forename: Anastasios
authors.initials: A
authors.lastname: Bonakis
authors.forename: Christos
authors.initials: C
authors.lastname: Christodoulou
authors.forename: George
authors.initials: G
authors.lastname: Klouvas
authors.forename: Angeliki
authors.initials: A
authors.lastname: Drougou
authors.forename: Drougou
authors.initials: D
authors.lastname: Angeliki
authors.forename: Dimostenis
authors.initials: D
authors.lastname: Skarlos
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy / Q000556:secondary; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy; D000068818:Cetuximab; D003110:Colonic Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D000077146:Irinotecan; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy; D008113:Liver Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009135:Muscular Diseases / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D010257:Paraneoplastic Syndromes / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D014376:Tuberculosis / Q000150:complications / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D000077146:Irinotecan; D000068818:Cetuximab; D008775:Methylprednisolone; D002166:Camptothecin