A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery.
Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.
Millner
Russell W J
RW
Department of Cardiothoracic Surgery, Blackpool Victoria Hospital, Blackpool, United Kingdom. russellmillner@btinternet.com
Lockhart
Alan S
AS
Bird
Helen
H
Alexiou
Christos
C
D016063:Blood Loss, Surgical / Q000517:prevention & control; D048271:Chitosan / Q000008:administration & dosage*; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods; D005500:Follow-Up Studies; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013908:Thoracotomy / Q000009:adverse effects* / Q000379:methods; D016896:Treatment Outcome; D014950:Wounds, Penetrating / Q000175:diagnosis / Q000628:therapy
D006490:Hemostatics; D048271:Chitosan