title: Spinal cord involvement in Balo's concentric sclerosis.
abstract: We present a patient with a history of myelitis, who had a steroid refractory attack of CNS inflammatory demyelinating disease that developed into cerebral concentric sclerosis of Balo after plasma exchange. The acute inflammatory disease involved the spinal cord, a phenomenon rarely demonstrated. This patient fulfilled the McDonald criteria for multiple sclerosis. Plasmapheresis did not have a beneficial effect, but the patient stabilised at high EDSS after treatment with mitoxantron.
authors.affiliation: Erasmus MC, University Medical Center, Department of Neurology, Rotterdam, The Netherlands.
authors.forename: Karim L
authors.initials: KL
authors.lastname: Kreft
authors.forename: S Jouke
authors.initials: SJ
authors.lastname: Mellema
authors.forename: Rogier Q
authors.initials: RQ
authors.lastname: Hintzen
mesh_terms: D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000175:diagnosis* / Q000628:therapy; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis; D009187:Myelitis / Q000150:complications / Q000628:therapy; D009483:Neuropsychological Tests; D010951:Plasma Exchange / Q000009:adverse effects*; D010956:Plasmapheresis; D013116:Spinal Cord / Q000473:pathology; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000628:therapy