title: [Therapeutic efficacy of buparvaquone (buparvon) in cattle with theileriosis].
abstract: The aim of this study was to examine the efficacy of buparvaquone (Buparvon, ALKE, Istanbul) in the treatment of theileriosis in cattle. The causative agent T. annulata causes direct and indirect gross economical loss in Turkey. Theileriosis was microscopically diagnosed by determining the presence of piroplasms in erythrocytes in thin blood smears stained with Giemsa stain. Buparvaquone was administered intramuscularly to the cattle with theileriosis using a single dose of 2.5 mg/kg. Clinical and laboratory examinations in cattle with theileriosis were carried out before and on the first, third and seventh days after treatment. As a result, it was concluded that a single deep intramuscular dose of 2.5 mg/kg buparvaquone was effective in the treatment of cattle which are naturally infected with T. annulata. However, further studies are needed using control groups of the same breed and age including suitable numbers of naturally infected and experimentally infected cattle.
authors.affiliation: Adnan Menderes Universitesi Veteriner Fakültesi, Iç Hastaliklari Anabilim Dali, Aydin, Turkey. pasa.serdar@hotmail.com
authors.forename: Bariş
authors.initials: B
authors.lastname: Saruhan
authors.forename: Serdar
authors.initials: S
authors.lastname: Paşa
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D004912:Erythrocytes / Q000469:parasitology; D007273:Injections, Intramuscular / Q000662:veterinary; D009285:Naphthoquinones / Q000008:administration & dosage / Q000627:therapeutic use*; D013801:Theileriasis / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; D009285:Naphthoquinones; C046326:buparvaquone