title: [HPLC fingerprint analysis of cordyceps and mycelium of cultured cordy].
abstract: OBJECTIVE
  To establish HPLC fingerprints of cordyceps and mycelium of cultured cordy for quality control.
  
  
  METHODS
  The analysis was carried out on a Diamonsil C18 column eluted with phosphate buffer (pH 6.5) and methanol as mobile phase, the gradient elution program was used, and the detection wavelength was 260 nm; The similarity of fingerprints was evaluated, then, cluster analysis was studied.
  
  
  RESULTS
  The method of HPLC fingerprint analysis was validated and in keeping with the requirement. Ten common peaks were found in HPLC fingerprint. Cordyceps from different areas and mycelium of cultured cordy could be distinguished by the HPLC fingerprint.
  
  
  CONCLUSIONS
  All results above exhibit that this method is practicable, reproducible, and reliable as a method for the quality control of cordyceps and mycelium of cultured cordy at present.
authors.affiliation: PLA Institute of Chinese Materia Medica, 302 Hospital of PLA, Beijing 100039, China.
authors.forename: Yan-Shu
authors.initials: YS
authors.lastname: Wu
authors.forename: Dan-Lei
authors.initials: DL
authors.lastname: Zhou
authors.forename: Dan
authors.initials: D
authors.lastname: Yan
authors.forename: Yong-Shen
authors.initials: YS
authors.lastname: Ren
authors.forename: Yi-Lin
authors.initials: YL
authors.lastname: Fang
authors.forename: Xiao-He
authors.initials: XH
authors.lastname: Xiao
authors.forename: Xiao-Xi
authors.initials: XX
authors.lastname: Du
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D032661:Cordyceps / Q000737:chemistry*; D025282:Mycelium / Q000737:chemistry*; D015203:Reproducibility of Results