title: Fabrication of enzymatic glucose biosensor based on palladium nanoparticles dispersed onto poly(3,4-ethylenedioxythiophene) nanofibers.
abstract: A new methodology involving the combination of a soft template (surfactant) and an ionic liquid (co-surfactant) is used to electrodeposit poly(3,4-ethylenedioxythiophene) (PEDOT) nanofibers. Electrochemical deposition of palladium nanoparticles and glucose oxidase (GOx) immobilization are done sequentially into nanofibrous PEDOT to fabricate the modified electrode (ME) (denoted as PEDOT-Pd/GOx-ME). The PEDOT-Pd/GOx-ME displays excellent performances for glucose at +0.4 V (vs. Ag/AgCl) with a high sensitivity (1.6 mA M(-)(1) cm(-2)) in a wider linear concentration range, 0.5 to 30 mM (correlation coefficient of 0.9985). Further, the electrode is insusceptible to the electroactive interfering species.
authors.affiliation: Department of Chemistry Graduate School, Kyungpook National University, Daegu 702-701, South Korea.
authors.forename: P
authors.initials: P
authors.lastname: Santhosh
authors.forename: K M
authors.initials: KM
authors.lastname: Manesh
authors.forename: S
authors.initials: S
authors.lastname: Uthayakumar
authors.forename: S
authors.initials: S
authors.lastname: Komathi
authors.forename: A I
authors.initials: AI
authors.lastname: Gopalan
authors.forename: K-P
authors.initials: KP
authors.lastname: Lee
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism*; D005947:Glucose / Q000032:analysis* / Q000378:metabolism; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism*; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010165:Palladium / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D004800:Enzymes, Immobilized; D011108:Polymers; C121383:poly(3,4-ethylene dioxythiophene); D014867:Water; D010165:Palladium; D005949:Glucose Oxidase; D005947:Glucose