title: Cold infusion for salvage partial hilar nephrectomy in patient with bilateral wilms tumor.
abstract: We describe the use of an ice-cold solution of Ringer's lactate with additives to ameliorate ischemia-reperfusion injury and avoid renal failure in a child with bilateral Wilms tumor requiring nonanatomic, hilar resection that would leave the patient with marginal renal parenchyma postoperatively. The adequate renal function afforded by the procedure avoided the possible need for dialysis and allowed the resection area to be irradiated to prevent tumor recurrence before eventual renal transplantation.
authors.affiliation: Department of Surgery, Division of Pediatric Surgery, DeWitt Daughtry Family, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Hogan
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Low
authors.forename: Gaetano
authors.initials: G
authors.lastname: Ciancio
authors.forename: George W
authors.initials: GW
authors.lastname: Burke
authors.forename: Joanna A
authors.initials: JA
authors.lastname: Davis
authors.forename: Juan E
authors.initials: JE
authors.lastname: Sola
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D017679:Cryotherapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D007677:Kidney Function Tests; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000628:therapy*; D009392:Nephrectomy / Q000379:methods*; D051437:Renal Insufficiency / Q000517:prevention & control; D012086:Reoperation / Q000379:methods; D015427:Reperfusion Injury / Q000517:prevention & control; D018570:Risk Assessment; D016879:Salvage Therapy / Q000379:methods*; D019354:Sodium Lactate / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000000981:diagnostic imaging / Q000601:surgery
chemical_list: D019354:Sodium Lactate