title: Endosulfan induces changes in spontaneous swimming activity and acetylcholinesterase activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes).
abstract: We assessed changes in spontaneous swimming activity and acetylcholinesterase (AchE) activity of Jenynsia multidentata exposed to Endosulfan (EDS). Females of J. multidentata were exposed to 0.072 and 1.4 microg L(-1) EDS. Average speed and movement percentage were recorded during 48 h. We also exposed females to EDS at five concentrations between 0.072 and 1.4 microg L(-1) during 24 h, and measured the AchE activity in brain and muscle. At 0.072 microg L(-1) EDS swimming motility decreased relative to the control group after 45 h, while at 1.4 microg L(-1) EDS swimming motility decreased after 24 h. AchE activity significantly decreased in muscle when J. multidentata were exposed to EDS above 0.072 microg L(-1), while no significant changes were observed in brain. Thus, changes in swimming activity and AchE activity in muscle are good biomarkers of exposure to EDS in J. multidentata.
authors.affiliation: Facultad de Ciencias Exactas, Físicas y Naturales, Cátedra Diversidad Animal II, Universidad Nacional de Córdoba, Av. Vélez Sársfield 299, 5000 Córdoba, Argentina.
authors.forename: M L
authors.initials: ML
authors.lastname: Ballesteros
authors.forename: P E
authors.initials: PE
authors.lastname: Durando
authors.forename: M L
authors.initials: ML
authors.lastname: Nores
authors.forename: M P
authors.initials: MP
authors.lastname: Díaz
authors.forename: M A
authors.initials: MA
authors.lastname: Bistoni
authors.forename: D A
authors.initials: DA
authors.lastname: Wunderlin
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology; D003532:Cyprinodontiformes / Q000502:physiology*; D004726:Endosulfan / Q000494:pharmacology*; D005260:Female; D007306:Insecticides / Q000494:pharmacology*; D007928:Lethal Dose 50; D009132:Muscles / Q000201:enzymology; D013550:Swimming / Q000502:physiology; D023382:Toxicity Tests, Acute; D014874:Water Pollutants, Chemical / Q000494:pharmacology*
chemical_list: D007306:Insecticides; D014874:Water Pollutants, Chemical; D000110:Acetylcholinesterase; D004726:Endosulfan