Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).
The topical use of platelet concentrates is recent and its efficiency remains controversial. Several techniques for platelet concentrates are available; however, their applications have been confusing because each method leads to a different product with different biology and potential uses. Here, we present classification of the different platelet concentrates into four categories, depending on their leucocyte and fibrin content: pure platelet-rich plasma (P-PRP), such as cell separator PRP, Vivostat PRF or Anitua's PRGF; leucocyte- and platelet-rich plasma (L-PRP), such as Curasan, Regen, Plateltex, SmartPReP, PCCS, Magellan or GPS PRP; pure plaletet-rich fibrin (P-PRF), such as Fibrinet; and leucocyte- and platelet-rich fibrin (L-PRF), such as Choukroun's PRF. This classification should help to elucidate successes and failures that have occurred so far, as well as providing an objective approach for the further development of these techniques.
Dohan Ehrenfest
David M
DM
Department of Biomaterials, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg, Sweden. LoB5@mac.com
Rasmusson
Lars
L
Albrektsson
Tomas
T
D001781:Blood Component Removal / Q000379:methods*; D001792:Blood Platelets / Q000166:cytology* / Q000378:metabolism*; D005337:Fibrin / Q000032:analysis*; D007962:Leukocytes / Q000166:cytology*; D010976:Platelet Count / Q000379:methods*; D053657:Platelet-Rich Plasma / Q000166:cytology* / Q000378:metabolism*; D010983:Plateletpheresis / Q000379:methods*
D005337:Fibrin