title: Gender differences in the Colorado Stroke Registry.
abstract: OBJECTIVE
  Gender differences in stroke are matters of increasing interest. The American Stroke Association's patient management tool, Get with the Guidelines-Stroke (GGS) is widely used to increase adherence to quality indicators in stroke care, but it also provides an opportunity to analyze gender differences in the acute stroke setting.
  
  
  METHODS
  We used a state-wide database, based on GGS, to explore gender differences in stroke in Colorado. We analyze demographics, risk factors, lifestyles, treatments, and responses to treatment.
  
  
  RESULTS
  Of 126 data elements examined, statistically significant gender differences were noted for 47 (37%). As compared to men, women in Colorado were older and more significantly impacted by acute stroke. Risk factor profiles differed between the 2 genders, with men having a higher incidence of coronary artery disease, dyslipidemia, diabetes, carotid stenosis and tobacco smoking, while women had a higher incidence of atrial fibrillation and hypertension. Lipids were less aggressively treated and antithrombotics were less commonly used in women. Overall, acute stroke treatment of women appeared "less aggressive" than for men.
  
  
  CONCLUSIONS
  GGS may be used not only for quality improvement initiatives in individual hospitals. It can also give an overview of clinical aspects of stroke at a state level, and may shed light on gender differences.
authors.affiliation: Colorado Stroke Alliance and Colorado Neurological Institute, Engelwood, Colorado, USA. dbsmd@qwest.net
authors.forename: Don B
authors.initials: DB
authors.lastname: Smith
authors.forename: Paul
authors.initials: P
authors.lastname: Murphy
authors.forename: Patricia
authors.initials: P
authors.lastname: Santos
authors.forename: Merrilee
authors.initials: M
authors.lastname: Phillips
authors.forename: Marsha
authors.initials: M
authors.lastname: Wilde
mesh_terms: D000208:Acute Disease; D000368:Aged; D001281:Atrial Fibrillation / Q000453:epidemiology; D016893:Carotid Stenosis / Q000453:epidemiology; D003120:Colorado / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D050171:Dyslipidemias / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D007348:Insurance, Health / Q000706:statistics & numerical data; D008019:Life Style; D008297:Male; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D012727:Sex Characteristics; D017678:Sex Distribution; D012907:Smoking / Q000453:epidemiology; D020521:Stroke / Q000453:epidemiology* / Q000628:therapy*; D016896:Treatment Outcome