title: Multi-detector row CT angiography with direct intra-arterial contrast injection for the evaluation of neurovascular disease: technique, applications, and initial experience.
abstract: The purpose of this study was to evaluate the usefulness of 64-section multi-detector row CT angiography (CTA) with direct intra-arterial contrast injection (IA-CTA) for the evaluation of neurovascular disease. This technique was used in 11 patients at our institution. All studies were technically successful, and there were no complications. Small vascular malformations were mapped easily on high-resolution IA-CTA images, enabling microsurgical resection or stereotactic radiosurgery. In a similar fashion, additional morphologic features were revealed on IA-CTA images not seen on standard 2D and 3D digital subtraction angiography. Of 11 patients undergoing IA-CTA, 7 patients had further anatomic clarity of the small arteriovenous fistula/malformation and 4 patients had changes in the treatment plan on the basis of the IA-CTA findings.
authors.affiliation: Division of Interventional Neuroradiology, Russell H. Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. dgandhi2@jhmi.edu
authors.forename: D
authors.initials: D
authors.lastname: Gandhi
authors.forename: A
authors.initials: A
authors.lastname: Pandey
authors.forename: S A
authors.initials: SA
authors.lastname: Ansari
authors.forename: J J
authors.initials: JJ
authors.lastname: Gemmete
authors.forename: B G
authors.initials: BG
authors.lastname: Thompson
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherji
mesh_terms: D002533:Cerebral Angiography / Q000379:methods*; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D007472:Iohexol / Q000008:administration & dosage*; D008297:Male; D010865:Pilot Projects; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol