title: [Early symptoms of frontotemporal lobar degeneration].
abstract: Frontotemporal lobar degeneration (FTLD) is the third most common cause of cortical dementia, following Alzheimer disease and dementia with Lewy body. Clinical criteria of FTLD were reviewed, and the initial symptoms, early neuropsychological and behavioral characteristics were also reviewed. In our own 205 ALS patients, 20 patients were dementia with ALS. In those cases, early and progressive loss of social awareness and insight and paragraphia were frequently observed. In ALS patients, especially patients with bulbar symptoms, we must carefully examine the mental functions and study the brains with MRI and SPECT/PET for detection of frontotemporal dysfunction.
authors.affiliation: Department of Neurology, Gunma University Graduate School of Medicine.
authors.forename: Koichi
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000544:Alzheimer Disease; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D003704:Dementia / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D003937:Diagnosis, Differential; D006801:Humans; D012015:Reference Standards