title: Pharmacokinetic study of sodium trans[tetrachlorobis(1H-indazole)-ruthenate (III)]/-indazole hydrochloride (1:1.1) (FFC14A) in patients with solid tumors.
authors.affiliation: Universitatsklinikum Essen, Essen, Germany. magdalena.henke@uni.essen.de
authors.forename: M M
authors.initials: MM
authors.lastname: Henke
authors.forename: H
authors.initials: H
authors.lastname: Richly
authors.forename: A
authors.initials: A
authors.lastname: Drescher
authors.forename: M
authors.initials: M
authors.lastname: Grubert
authors.forename: D
authors.initials: D
authors.lastname: Alex
authors.forename: D
authors.initials: D
authors.lastname: Thyssen
authors.forename: U
authors.initials: U
authors.lastname: Jaehde
authors.forename: M E
authors.initials: ME
authors.lastname: Scheulen
authors.forename: R A
authors.initials: RA
authors.lastname: Hilger
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood / Q000737:chemistry; D017321:Clinical Trials, Phase I as Topic; D017322:Clinical Trials, Phase II as Topic; D018736:DNA Adducts / Q000097:blood / Q000737:chemistry; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D006801:Humans; D007191:Indazoles / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000627:therapeutic use; D007262:Infusions, Intravenous; D007962:Leukocytes / Q000737:chemistry; D008657:Metabolic Clearance Rate; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism*; D009942:Organometallic Compounds; D017975:Ruthenium Compounds / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000627:therapeutic use; D012709:Serum Albumin / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D014168:Transferrin / Q000032:analysis / Q000737:chemistry / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers; D018736:DNA Adducts; D007191:Indazoles; D009942:Organometallic Compounds; D017975:Ruthenium Compounds; D012709:Serum Albumin; D014168:Transferrin; C499292:indazolium trans-(tetrachlorobis(1H-indazole)ruthenate (III))