Fat rationing in dauer times.
The fundamental task of maintaining energy balance is complex when nutrient levels are plentiful, but it becomes even more challenging when nutrients are dynamic or scarce. A recent Nature report delineates a role of the AMP kinase pathway in rationing energy stores for the long-term survival of Caenorhabditis elegans dauers (Narbonne and Roy, 2009).
Cunningham
Katherine A
KA
Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA.
Ashrafi
Kaveh
K
D055372:AMP-Activated Protein Kinases / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D017173:Caenorhabditis elegans / Q000201:enzymology / Q000254:growth & development*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism*; D004734:Energy Metabolism; D005227:Fatty Acids / Q000378:metabolism*; D007814:Larva / Q000201:enzymology; D008049:Lipase / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*; D011972:Receptor, Insulin / Q000378:metabolism; D040521:Subcutaneous Tissue / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism
D029742:Caenorhabditis elegans Proteins; D005227:Fatty Acids; D014280:Triglycerides; C107483:DAF-2 protein, C elegans; D011972:Receptor, Insulin; D017346:Protein Serine-Threonine Kinases; C510541:AAK-2 protein, C elegans; D055372:AMP-Activated Protein Kinases; D008049:Lipase