title: Atrial fibrillation and heart failure.
abstract: Atrial fibrillation (AF) is the most common arrhythmia in congestive heart failure (HF) and indicates a worse prognosis. AF increases HF symptoms and increases in prevalence with increasing New York Heart Association class. AF also interferes with the ideal management of HF. Across all HF etiologies, AF may be a marker of disease severity. Yet, controversies exist regarding whether strategies to restore and maintain sinus rhythm can improve outcomes in HF. It is also unclear what the optimal strategy is to suppress the ventricular response to AF in patients with HF. As HF incidence and prevalence continue to rise, the authors sought to reinvestigate current literature that relates AF to HF and examine the impact of therapy on HF and/or AF. The authors performed a literature review using a MEDLINE search from 1966 to the present and included existing literature based on their strength of evidence.
authors.affiliation: Division of Cardiology, Center for Heart Failure Therapy and Transplantation, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Larned
authors.forename: S
authors.initials: S
authors.lastname: Raja Laskar
mesh_terms: D001281:Atrial Fibrillation / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D015415:Biomarkers; D006333:Heart Failure / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D015994:Incidence; D011379:Prognosis; D012307:Risk Factors; D014481:United States / Q000453:epidemiology
chemical_list: D015415:Biomarkers