title: [Chlamydia infection in patients with and without cervical intra-epithelial lesions].
abstract: OBJECTIVE
  To determine the frequency of Chlamydia trachomatis infection in patients with and without intraepithelial cervical lesions attended at specialized ambulatory in Recife (2007) and its association with biologic and demographic variables, habits, reproductive, clinical and gynecologic characteristics.
  
  
  METHODS
  A cross-sectional study was conducted including 70 women (35 with cytological cervical lesions and 35 with normal smears). Colposcopy and biopsy when necessary were performed and Chlamydia infection was determined by direct immunofluorescence. Analysis variables were age, race, precedence, schooling, marital status, menarche, age at first sexual intercourse, parity, number of sexual partners, vaginal discharge, previous Pap smear, STD episodes, cervical cauterization, contraceptive methods, familial antecedents of cervical cancer, alcohol intake, use of illicit and immunosuppressive drugs, Papanicolaou result and cervical Chlamydia l infection. To determine the strength of association prevalence ratio (PR) and its 95% confidence interval were calculated. Multivariate analysis was performed for controlling potentially confounding variables.
  
  
  RESULTS
  the frequency of Chlamydia l infection was significantly greater in patients with intraepithelial cervical lesions (80.0% vs. 14.3%; PR=5.60; 95% CI=2.44-12.82). When the factors associated with Chlamydia l infection were analyzed, the only variable that remained significantly associated after multivariate analysis was previous episode of STD (OR=63.47; 95% CI=13.93-289.09).
  
  
  CONCLUSIONS
  Chlamydia trachomatis infection is associated with intraepithelial cervical lesions and history of STD should be considered for treatment and follow-up of these patients.
authors.affiliation: Instituto Materno-Infantil Prof. Fernando Figueira, Recife, PE
authors.forename: Micheline de Lucena
authors.initials: Mde L
authors.lastname: Oliveira
authors.forename: Melania Maria Ramos de
authors.initials: MM
authors.lastname: Amorim
authors.forename: Alex Sandro Rolland de
authors.initials: AS
authors.lastname: Souza
authors.forename: Lúcia Cristina Bezerra de
authors.initials: LC
authors.lastname: Albuquerque
authors.forename: Aurélio Antônio Ribeiro da
authors.initials: AA
authors.lastname: Costa
mesh_terms: D000328:Adult; D001706:Biopsy; D001938:Brazil / Q000453:epidemiology; D002584:Cervix Uteri / Q000473:pathology*; D002690:Chlamydia Infections / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D003127:Colposcopy; D003430:Cross-Sectional Studies; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D016015:Logistic Models; D012725:Sexual Behavior; D012747:Sexual Partners; D012959:Socioeconomic Factors; D002583:Uterine Cervical Neoplasms / Q000382:microbiology* / Q000473:pathology*; D002578:Uterine Cervical Dysplasia / Q000473:pathology