title: Biochemical parameters in chronic fascioliasis.
abstract: Serum lipids, liver enzymes and total bile acids were measured in chronic Fasciola (cholestatic and non-cholestatic) patients. Variations in the biochemical parameters between infected and control groups were detected and typified by considerably higher serum triglycerides (TG, P < 0.001), alkaline phosphatase (ALP, P< 0.001) and total bile acids (TBA, P < 0.001) in the infected group. For cholestatic patients, TG, very low density lipoprotein (VLDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gammaglutamyl transferase (GGT) and ALP were statistically higher (P < 0.001 for each comparison) and total cholesterol (TC); low density lipoprotein (LDL) and high density lipoprotein (HDL), were statistically lower than non-cholestatic patients (P = 0.02, < 0.001, < 0.001 respectively). No statistically significant differences were found for the TC, HDL, VLDL, ALT, AST and GGT between non-cholestatic patients and healthy controls.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
authors.forename: Atef M
authors.initials: AM
authors.lastname: El-Shazly
authors.forename: Manar S
authors.initials: MS
authors.lastname: Azab
authors.forename: Samar N
authors.initials: SN
authors.lastname: El-Beshbishi
authors.forename: Tarek I
authors.initials: TI
authors.lastname: Sakr
authors.forename: Khaled N
authors.initials: KN
authors.lastname: El-Fayoumy
authors.forename: Aza S
authors.initials: AS
authors.lastname: El-Ghareeb
authors.forename: Adel O
authors.initials: AO
authors.lastname: Hafez
authors.forename: Eman T
authors.initials: ET
authors.lastname: El Sherbini
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001647:Bile Acids and Salts / Q000032:analysis*; D016022:Case-Control Studies; D002779:Cholestasis / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D005211:Fascioliasis / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000201:enzymology*; D012720:Severity of Illness Index; D014280:Triglycerides / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D001647:Bile Acids and Salts; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase