title: Adsorption properties of proteins on SBA-15 nanoparticles functionalized with aminosilanes.
abstract: Since the discovery of ordered mesoporous silica M41S in 1992, a variety of ordered mesoporous materials have been synthesized by using the template technique. In this work, aminosilane-modified SBA-15 nanoparticles were prepared by incorporating various aminosilanes on original SBA-15 via post synthesis method. These aminosilanes were 3-aminopropyltriethoxysilane, N-2(-aminoethyl)-3-aminopropyl trimethoxysilane and (3-trimethoxysilylpropyl)diethylenetriamine. The synthesized nanoparticles were characterized by XRD, SEM, TEM and FT-IR. Adsorption and release studies of bovine serum albumin (BSA), lysozyme and myoglobin on SBA-15 samples were investigated. It was found that the synthesized SBA-15 nanoparicles can be successfully applied in drug delivery system.
authors.affiliation: Department of Chemical and Biochemical Engineering, Chosun University, Gwangju 501-759, Republic of Korea.
authors.forename: Jae-Wook
authors.initials: JW
authors.lastname: Lee
authors.forename: Pham Thi
authors.initials: PT
authors.lastname: Tra
authors.forename: Sul-Il
authors.initials: SI
authors.lastname: Kim
authors.forename: Sung-Hee
authors.initials: SH
authors.lastname: Roh
mesh_terms: D000327:Adsorption; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles; D011506:Proteins / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D011506:Proteins; C509969:SBA-15; D012821:Silanes; D012822:Silicon Dioxide