title: Long-term survival of patients diagnosed with non-Hodgkin lymphoma after a previous malignancy.
abstract: An increased risk of non-Hodgkin lymphoma (NHL) has been observed in the survivors of several malignancies. Survival for patients with primary NHL has improved in the 1990 s and early 21st century, but population-based survival data for patients diagnosed with NHL after a prior malignancy are lacking. We estimated trends in age-specific 5- and 10-year relative survival of NHL patients with prior malignancy in the United States from 1990-1994 to 2000-2004 using the Surveillance, Epidemiology and End Results Program database. Period analysis of survival was employed to disclose recent developments with minimum delay. Five- and 10-year relative survival has strongly improved for NHL patients with prior malignancy between 1990-1994 and 2000-2004, from 38.0 to 54.1% and 24.4 to 41.0%, respectively. Despite a strong increase in relative survival over time, patients with prior malignancies continued to have a worse prognosis compared with those with no prior malignancy.
authors.affiliation: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
authors.forename: Dianne
authors.initials: D
authors.lastname: Pulte
authors.forename: Adam
authors.initials: A
authors.lastname: Gondos
authors.forename: Hermann
authors.initials: H
authors.lastname: Brenner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000453:epidemiology*; D015996:Survival Rate; D013997:Time Factors