title: Urine heteroplasmy is the best predictor of clinical outcome in the m.3243A>G mtDNA mutation.
authors.affiliation: Mitochondrial Research Group, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. r.whittaker@ncl.ac.uk
authors.forename: R G
authors.initials: RG
authors.lastname: Whittaker
authors.forename: J K
authors.initials: JK
authors.lastname: Blackwood
authors.forename: C L
authors.initials: CL
authors.lastname: Alston
authors.forename: E L
authors.initials: EL
authors.lastname: Blakely
authors.forename: J L
authors.initials: JL
authors.lastname: Elson
authors.forename: R
authors.initials: R
authors.lastname: McFarland
authors.forename: P F
authors.initials: PF
authors.lastname: Chinnery
authors.forename: D M
authors.initials: DM
authors.lastname: Turnbull
authors.forename: R W
authors.initials: RW
authors.lastname: Taylor
mesh_terms: D000328:Adult; D000368:Aged; D004272:DNA, Mitochondrial / Q000235:genetics* / Q000652:urine*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D028361:Mitochondrial Diseases / Q000175:diagnosis* / Q000235:genetics* / Q000652:urine; D009154:Mutation; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011379:Prognosis; D012322:RNA Precursors / Q000235:genetics*; D012356:RNA, Transfer, Leu / Q000235:genetics*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D004272:DNA, Mitochondrial; D012322:RNA Precursors; D012356:RNA, Transfer, Leu; C091001:pre-tRNA(Leu)