title: [New therapeutic strategy for mitochondrial diseases].
abstract: Mitochondrial diseases have a peculiar character of variability that expands from DNA, cell and tissue/organ levels to family/society level. These kinds of variability seem an obstacle to prevent us from developing new and effective therapies for this disease. Selective delivery system to mitochondria can make us get a promising new strategy to treat and prevent the disease. MITO-Porter may be a powerful system in which we can introduce a various kind of materials including DNA, RNA, enzyme and drugs to mitochondria in vivo.
authors.affiliation: National Institute of Neuroscience, NCNP.
authors.forename: Yu-ichi
authors.initials: Y
authors.lastname: Goto
mesh_terms: D016503:Drug Delivery Systems; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D008081:Liposomes; D028361:Mitochondrial Diseases / Q000628:therapy*
chemical_list: D008081:Liposomes