title: Giant cell tumor of the sternum: a case report and review of the literature.
abstract: Giant cell tumor (GCT) is a relatively common and locally aggressive benign bone tumor. The sternum is a rare location. To date, only four cases have been reported with detailed information. Here, we present a case with sternal GCT and discuss the clinical manifestation and treatment, in addition to reviewing the literature. A 53-year-old female noted pain in the sternum after a trauma. Radiographic findings revealed an expanding osteolytic lesion in the body of the sternum. Extended curettage of the tumor was performed followed by polymethylmethacrylate (PMMA) filing. No recurrence was found over a 7-year follow-up period. In conclusion, even though sternal benign tumors are rare, GCT should be considered as one of the differential diagnoses in a patient presenting with a sternal lesion in the 5th or 6th decade of life. The initial treatment should be extended curettage followed by filling with PMMA.
authors.affiliation: Department of Orthopaedic Surgery, Hyogo College of Medicine, 1-1 Mukogawa Nishinomiya, Hyogo 663-8501, Japan. h-futani@hyo-med.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Futani
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Okumura
authors.forename: Yuko
authors.initials: Y
authors.lastname: Fukuda
authors.forename: Satoru
authors.initials: S
authors.lastname: Fukunaga
authors.forename: Seiki
authors.initials: S
authors.lastname: Hasegawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yoshiya
mesh_terms: D001843:Bone Cements; D001859:Bone Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D019904:Polymethyl Methacrylate; D019651:Plastic Surgery Procedures / Q000379:methods; D013249:Sternum / Q000473:pathology* / Q000601:surgery
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate