title: Targeting exofacial protein thiols with Gd(III) complexes. An efficient procedure for MRI cell labelling.
abstract: Cells display on the outer surface of the plasma membrane a large number of protein thiols that can be reversibly labelled with suitably designed Gd(III)-based contrast agents for cell tracking by MRI.
authors.affiliation: Department of Environmental and Life Sciences, University of Eastern Piedmont "A. Avogadro", Via Bellni 25G, 15100 Alessandria, Italy. giuseppe.digilio@mfn.unipmn.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Digilio
authors.forename: Valeria
authors.initials: V
authors.lastname: Catanzaro
authors.forename: Franco
authors.initials: F
authors.lastname: Fedeli
authors.forename: Eliana
authors.initials: E
authors.lastname: Gianolio
authors.forename: Valeria
authors.initials: V
authors.lastname: Menchise
authors.forename: Roberta
authors.initials: R
authors.lastname: Napolitano
authors.forename: Concetta
authors.initials: C
authors.lastname: Gringeri
authors.forename: Silvio
authors.initials: S
authors.lastname: Aime
mesh_terms: D002462:Cell Membrane / Q000378:metabolism*; D022082:Cellular Structures / Q000737:chemistry; D003287:Contrast Media / Q000737:chemistry* / Q000378:metabolism; D005682:Gadolinium / Q000737:chemistry*; D006801:Humans; D020014:K562 Cells; D046911:Macromolecular Substances; D008279:Magnetic Resonance Imaging / Q000379:methods; D015394:Molecular Structure; D011506:Proteins; D013194:Staining and Labeling / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D046911:Macromolecular Substances; D011506:Proteins; D013438:Sulfhydryl Compounds; D005682:Gadolinium