Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation.
OBJECTIVE
Sexual functioning is an important component of women's lives. The extent to which the menopausal transition is associated with decreased sexual functioning remains inconclusive. This study seeks to determine if advancing through the menopausal transition is associated with changes in sexual functioning.


METHODS
This was a prospective, longitudinal cohort study of women aged 42 to 52 years at baseline recruited at seven US sites (N = 3,302) in the Study of Women's Health Across the Nation (SWAN). Cohort-eligible women had an intact uterus, had at least one ovary, were not currently using exogenous hormones, were either premenopausal or early perimenopausal, and self-identified as one of the study's designated racial/ethnic groups. Data from the baseline interview and six annual follow-up visits are reported. Outcomes are self-reported ratings of importance of sex; frequency of sexual desire, arousal, masturbation, sexual intercourse, and pain during intercourse; and degree of emotional satisfaction and physical pleasure.


RESULTS
With adjustment for baseline age, chronological aging, and relevant social, health, and psychological parameters, the odds of reporting vaginal or pelvic pain increased and desire decreased by late perimenopause. Masturbation increased at early perimenopause but declined during postmenopause. The menopausal transition was unrelated to other outcomes. Health, psychological functioning, and importance of sex were related to all sexual function outcomes. Age, race/ethnicity, marital status, change in relationship, and vaginal dryness were also associated with sexual functioning.


CONCLUSIONS
Pain during sexual intercourse increases and sexual desire decreases over the menopausal transition. Masturbation increases during the early transition, but then declines in postmenopause. With adjustment for other factors, the menopausal transition was not independently associated with reports of the importance of sex, sexual arousal, frequency of sexual intercourse, emotional satisfaction with partner, or physical pleasure.
Avis
Nancy E
NE
Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1063, USA. navis@wfubmc.edu
Brockwell
Sarah
S
Randolph
John F
JF
Shen
Shunhua
S
Cain
Virginia S
VS
Ory
Marcia
M
Greendale
Gail A
GA
D000328:Adult; D000375:Aging / Q000502:physiology*; D004414:Dyspareunia; D005260:Female; D006306:Health Surveys; D006801:Humans; D008137:Longitudinal Studies; D008418:Masturbation; D008593:Menopause / Q000502:physiology*; D008875:Middle Aged; D016017:Odds Ratio; D011446:Prospective Studies; D019529:Sexuality / Q000502:physiology*