Clinical, radiological and histological evaluation of biphasic calcium phosphate bioceramic wedges filling medial high tibial valgisation osteotomies.
We report clinical, radiological and histological findings following high tibial valgisation osteotomy (HTVO) using micro-macroporous biphasic calcium phosphate wedges fixed with a plate and locking screws. From 1999 to 2002, 43 knees were operated on and studied prospectively. All underwent clinical and radiological follow-up at days 1, 90, and 365 to evaluate consolidation and bone substitute interfaces. Additionally, biopsies were taken for histology at least 1 year after implantation from 10 patients who requested plate removal. Radiologically, consolidation was observed in 98% of cases. At 1 year, correction was unchanged in 95% of cases. Histological analysis revealed considerable MBCP resorption and bone ingrowth, both into the pores and replacing the bioceramic material. Polarised light microscopy confirmed normal bony architecture with trabecular and/or dense lamellar bone growth at the expense of the wedge implants. X-ray and micro-CT scan revealed a well organised and mineralised structure in the newly-formed bone. This study shows that using MBCP wedges in combination with orientable locking screws and a plate is a simple, safe and fast surgical technique for HTVO. The is the first study to examine the results by histological analysis, which confirmed good outcomes.
Rouvillain
J L
JL
Orthopaedic Department, University La Meynard Hospital, 97261 Fort de France, Martinique. jlrouvillain@sasi.fr
Lavallé
F
F
Pascal-Mousselard
H
H
Catonné
Y
Y
Daculsi
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D001860:Bone Plates; D001863:Bone Screws; D018786:Bone Substitutes; D002130:Calcium Phosphates / Q000032:analysis; D002516:Ceramics; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D010027:Osteotomy / Q000295:instrumentation* / Q000379:methods; D011446:Prospective Studies; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery* / Q000648:ultrastructure
D018786:Bone Substitutes; D002130:Calcium Phosphates