title: A novel Brucella isolate in association with two cases of stillbirth in non-human primates - first report.
abstract: BACKGROUND
  Brucellosis is veterinary and human health problem.
  
  
  METHODS
  A 13-year-old wild caught multiparous and an 8-year-old colony-born nulliparous baboon had stillbirths in the second trimester of pregnancy. Culture isolates from both postpartum uteruses were characterized using traditional biochemical analysis, PCR, and multilocus sequencing.
  
  
  RESULTS
  The isolates morphologically resembled Brucella although their phenotypic characteristics were not consistent with any currently described species. The isolates represent a novel lineage within the genus with unique alleles, not previously seen in surveys of greater than 300 isolates representing the known diversity of the genus, present at 5/9 loci examined.
  
  
  CONCLUSIONS
  The described cases are to the best of our knowledge the first presentation of a naturally acquired Brucella infection in non-human primates associated with stillbirths from the same colony where Brucella seropositivity in the baboons was described 45 years ago. The organism appears to represent a previously undescribed Brucella species.
authors.affiliation: Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. schlabritzlu@uthscsa.edu
authors.forename: Natalia E
authors.initials: NE
authors.lastname: Schlabritz-Loutsevitch
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Whatmore
authors.forename: Christine R
authors.initials: CR
authors.lastname: Quance
authors.forename: Mark S
authors.initials: MS
authors.lastname: Koylass
authors.forename: L Bill
authors.initials: LB
authors.lastname: Cummins
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Dick
authors.forename: Cathy L
authors.initials: CL
authors.lastname: Snider
authors.forename: David
authors.initials: D
authors.lastname: Cappelli
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Ebersole
authors.forename: Peter W
authors.initials: PW
authors.lastname: Nathanielsz
authors.forename: Gene B
authors.initials: GB
authors.lastname: Hubbard
mesh_terms: D000818:Animals; D002002:Brucella / Q000235:genetics / Q000302:isolation & purification*; D002006:Brucellosis / Q000150:complications / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D005313:Fetal Death / Q000382:microbiology / Q000662:veterinary*; D005838:Genotype; D010215:Papio / Q000382:microbiology*; D011247:Pregnancy; D050497:Stillbirth / Q000662:veterinary*