title: Chikungunya virus and central nervous system infections in children, India.
abstract: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus best known for causing fever, rash, arthralgia, and occasional neurologic disease. By using real-time reverse transcription-PCR, we detected CHIKV in plasma samples of 8 (14%) of 58 children with suspected central nervous system infection in Bellary, India. CHIKV was also detected in the cerebrospinal fluid of 3 children.
authors.affiliation: University of Liverpool, Liverpool, UK. pennylewthwaite@doctors.org.uk
authors.forename: Penny
authors.initials: P
authors.lastname: Lewthwaite
authors.forename: Ravi
authors.initials: R
authors.lastname: Vasanthapuram
authors.forename: Jane C
authors.initials: JC
authors.lastname: Osborne
authors.forename: Ashia
authors.initials: A
authors.lastname: Begum
authors.forename: Jenna L M
authors.initials: JL
authors.lastname: Plank
authors.forename: M Veera
authors.initials: MV
authors.lastname: Shankar
authors.forename: Roger
authors.initials: R
authors.lastname: Hewson
authors.forename: Anita
authors.initials: A
authors.lastname: Desai
authors.forename: Nick J
authors.initials: NJ
authors.lastname: Beeching
authors.forename: Ravi
authors.initials: R
authors.lastname: Ravikumar
authors.forename: Tom
authors.initials: T
authors.lastname: Solomon
mesh_terms: D000293:Adolescent; D018354:Alphavirus Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000821:virology; D020805:Central Nervous System Viral Diseases / Q000097:blood / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000821:virology; D002555:Cerebrospinal Fluid / Q000821:virology; D002646:Chikungunya virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA