title: Fatal Ophiostoma piceae infection in a patient with acute lymphoblastic leukaemia.
abstract: We report to our knowledge the first case of human infection with Ophiostoma piceae. This Sporothrix schenckii-related fungus caused disseminated infection involving the lung and the brain in a patient with lymphoblastic lymphoma. The case emphasizes the significance of molecular techniques for identification of rare fungi in the clinical microbiology laboratory.
authors.affiliation: Department of Internal Medicine III, University Hospital of Ulm, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Bommer
authors.affiliation: Department of Internal Medicine III, University Hospital of Ulm, Germany.
authors.forename: Marie-Luise
authors.initials: ML
authors.lastname: Hütter
authors.affiliation: Department of Internal Medicine III, University Hospital of Ulm, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Stilgenbauer
authors.affiliation: Centraalbureau voor Schimmelcultures (CBS), Utrecht, The Netherlands.
authors.forename: G Sybren
authors.initials: GS
authors.lastname: de Hoog
authors.affiliation: Department of Microbiology and Plant Pathology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, South Africa.
authors.forename: Z Wilhelm
authors.initials: ZW
authors.lastname: de Beer
authors.affiliation: Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Germany.
authors.forename: Nele
authors.initials: N
authors.lastname: Wellinghausen
mesh_terms: D000328:Adult; D001483:Base Sequence; D001706:Biopsy; D001921:Brain / Q000382:microbiology / Q000601:surgery; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008969:Molecular Sequence Data; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D055156:Ophiostoma / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed