title: Essential thrombocythemia: a case of acute ST-segment elevation myocardial infarction in a young female.
abstract: Essential thrombocythemia (ET) is a clonal disorder of the myeloid stem cell that causes abnormal proliferation of the megakaryocytes. The main feature of the disease is arterial and venous thrombosis caused by platelet dysfunction. Coronary artery involvement leading to acute coronary syndromes is a rare complication of the ET. We report a coronary angioplasty and stenting in a 30-year-old female patient with acute ST-segment elevation myocardial infarction (MI) as the first clinical sign of essential thrombocythemia. Facilitated percutaneous coronary intervention with GPIIb/IIIa and/or thrombolytic therapy may be considered as the first treatment modality for this patient group.
authors.affiliation: Department of Cardiology, Kocaeli University, 41380 Kocaeli, Turkey. ihubildir@gmail.com
authors.forename: Ulas
authors.initials: U
authors.lastname: Bildirici
authors.forename: Umut
authors.initials: U
authors.lastname: Celikyurt
authors.forename: Ertan
authors.initials: E
authors.lastname: Ural
mesh_terms: D000328:Adult; D000367:Age Factors; D000986:Antisickling Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D000077144:Clopidogrel; D017023:Coronary Angiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000175:diagnosis; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D000077466:Tirofiban; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014443:Tyrosine / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000986:Antisickling Agents; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D014443:Tyrosine; D006493:Heparin; D000077144:Clopidogrel; D010959:Tissue Plasminogen Activator; D000077466:Tirofiban; D013988:Ticlopidine; D001241:Aspirin; D006918:Hydroxyurea