title: [Primary adrenal leiomyosarcoma].
abstract: Leiomyosarcoma of adrenal gland is an extremely rare tumor originating from the central adrenal vein or its tributaries. Patients with human immunodeficiency virus (HIV) and Epstein-Barr infection have a higher incidence of these tumors, but even in those, the overall incidence is very low. In this paper we report a case of a 48 year-old woman whose diagnosis was made by image exams that had suggested a mass in adrenal area. This patient was submitted to surgery for resection of the mass. The histopathologic and immunohistochemistry exams were compatible with primary leiomyosarcoma of adrenal gland. Fifty-three months after adrenalectomy the patient died with recurrent disease. Despite of the rarity of this tumor, leiomyosarcoma of adrenal gland has an aggressive behavior, such as the others soft tissue sarcomas. The adrenalectomy is the primary treatment, while chemotherapy or radiotherapy is not prescribed except in metastatic or bulky and inoperable disease.
authors.affiliation: Serviço de Cirurgia Abdominal, Hospital Erasto Gaertner, Liga Paranaense de Combate ao Câncer.
authors.forename: Flávio D Saavedra
authors.initials: FD
authors.lastname: Tomasich
authors.forename: Murilo de Almeida
authors.initials: Mde A
authors.lastname: Luz
authors.forename: Massakazu
authors.initials: M
authors.lastname: Kato
authors.forename: Giovanni Zenedin
authors.initials: GZ
authors.lastname: Targa
authors.forename: Luiz Antônio Negrão
authors.initials: LA
authors.lastname: Dias
authors.forename: Francielle Jorge
authors.initials: FJ
authors.lastname: Zucoloto
authors.forename: Daniel Cury
authors.initials: DC
authors.lastname: Ogata
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011859:Radiography