D-glucose-induced second harmonic generation response in human erythrocytes.
The first experimental results of the nonresonant second harmonic generation (SHG) studies of human erythrocytes membrane exposed to various glucose concentrations in phosphate buffered saline (PBS solution) are presented in this article. It is shown that the SHG signal from the membrane can be altered as a function of glucose concentration. The link between the variation of the SHG intensity and the membrane dielectric permittivity with glucose is established both theoretically and experimentally by comparison with time domain dielectric spectroscopy (TDDS) measurement data.
Lev
Dmitry
D
The Department of Applied Physics, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Puzenko
Alexander
A
Manevitch
Alexandra
A
Manevitch
Zacharia
Z
Livshits
Leonid
L
Feldman
Yuri
Y
Lewis
Aaron
A
D000465:Algorithms; D004594:Electrophysiology; D004910:Erythrocyte Membrane / Q000737:chemistry* / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects; D005947:Glucose / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans
D005947:Glucose