title: Infiltrating intramuscular spindle cell lipoma of the face.
abstract: Spindle cell lipoma is a benign lipomatous tumor, which usually arises on the back of the neck, shoulder or upper back of males in the third to seventh decade of life. We report herein an unusual infiltrating intramuscular spindle cell lipoma arising in the nose of a 53-year-old man. The patient presented with a 0.5-cm 'cyst' of the nose, just above the right alar crease, which was removed. Four years later, the lesion recurred and was re-excised. Histologically, a proliferation of mature adipocytes, ropey collagen fibers and spindle cells within a myxoid stroma was present in the subcutaneous tissue and infiltrated between skeletal muscle fibers. Nine cases of intramuscular spindle cell lipoma with histological examination have previously been reported and have involved the oral cavity and muscles of the extremities. To our knowledge, this is the first report of an infiltrating intramuscular spindle cell lipoma arising on the face.
authors.affiliation: Department of Pathology, Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA 02114, USA. rmandal@partners.org
authors.forename: Rajni V
authors.initials: RV
authors.lastname: Mandal
authors.forename: Lyn M
authors.initials: LM
authors.lastname: Duncan
authors.forename: William G
authors.initials: WG
authors.lastname: Austen
authors.forename: G Petur
authors.initials: GP
authors.lastname: Nielsen
mesh_terms: D003951:Diagnostic Errors; D006222:Hamartoma / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008067:Lipoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009669:Nose Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery