title: Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy.
abstract: Combined chemotherapy using carboplatin and paclitaxel has been established as a standard regimen for epithelial ovarian carcinoma. We present the case of a 36-year-old woman with ovarian mucinous cystadenocarcinoma who underwent exploratory laparotomy during pregnancy, revealing Stage 1c at gestational week 15. Afterwards, five courses of paclitaxel and carboplatin chemotherapy were administered biweekly from gestational week 24. Cesarean section was performed at gestational week 36. No recurrent or metastatic lesions were found and outcomes for both mother and neonate have been satisfactory for 40 months since diagnosis of ovarian carcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, Musashikosugi Hospital, Nippon Medical School, 1-396 Kosugitchou, Nakaharaku, Kawasaki, Kanagawa, 211-0063, Japan. d-dtk@nms.ac.jp
authors.forename: Daisuke
authors.initials: D
authors.lastname: Doi
authors.forename: Yumi
authors.initials: Y
authors.lastname: Boh
authors.forename: Hideki
authors.initials: H
authors.lastname: Konishi
authors.forename: Hirobumi
authors.initials: H
authors.lastname: Asakura
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Takeshita
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols; D016190:Carboplatin / Q000627:therapeutic use*; D018282:Cystadenocarcinoma, Mucinous / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D017239:Paclitaxel / Q000627:therapeutic use*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D016190:Carboplatin; D017239:Paclitaxel