title: Use of a multi-modality life support system.
abstract: The purpose of this study was to describe the design and utilization of a multi-modality life support system (MMLSS), which is used to provide extracorporeal support for cases such as left heart bypass (LHB), extracorporeal life support (ECLS), veno-venous bypass, and hypothermic resuscitation. The design of the MMLSS consisted of a mobile cart outfitted with a centrifugal pump, heater cooler, an in-line blood gas monitor, oxygen blender/flow meter, and assorted safety devices (pressure sensors and level and bubble detectors). A single disposable circuit was used for all procedures and designed to be easily modifiable to support a variety of clinical scenarios, with and without the use of an oxygenator. The system was designed for rapid deployment throughout the hospital. From January 1, 2006 to December 31, 2007, the MMLSS has been used in three LHB procedures (63 +/- 72 minutes), four adult ECLS cases (57.2 +/- 56.9 hours), four veno-venous bypasses (72 +/- 35 minutes), and one hypothermic resuscitation (182 minutes). The MMLSS was designed to be used in patients > 20 kg and could achieve flows in the range of 1-5.5 L. There were no complications associated with the device. The MMLSS is a versatile system that can be used throughout the hospital with a single disposable circuit, accommodating a diverse caseload in a safe and reproducible manner.
authors.affiliation: Geisinger Health System, Danville, Pennsylvania, USA. NPBrindisi@Geisinger.edu
authors.forename: Nicholas
authors.initials: N
authors.lastname: Brindisi
authors.forename: Alfred
authors.initials: A
authors.lastname: Stammers
authors.forename: Cody
authors.initials: C
authors.lastname: Trowbridge
authors.forename: Myra
authors.initials: M
authors.lastname: Klayman
authors.forename: James
authors.initials: J
authors.lastname: Pezzuto
authors.forename: Molly
authors.initials: M
authors.lastname: Marko
mesh_terms: D002315:Cardiopulmonary Bypass / Q000295:instrumentation* / Q000379:methods; D003131:Combined Modality Therapy / Q000295:instrumentation*; D004867:Equipment Design; D005112:Extracorporeal Circulation / Q000295:instrumentation / Q000379:methods; D018611:Heart Bypass, Left / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007036:Hypothermia, Induced