title: Highly efficient and regioselective platinum(II)-catalyzed tandem synthesis of multiply substituted indolines and tetrahydroquinolines.
abstract: A special advantage: The platinum(II)-catalyzed tandem cyclization of aminoalkynes with 1,3-diketones offers a new and highly efficient method for the synthesis of indolines and tetrahydroquinolines (see scheme; M.S. = molecular sieves). This transformation affords good to excellent product yields with high regio- and chemoselectivity under mild reaction conditions.
authors.affiliation: Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
authors.forename: Xin-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007211:Indoles; D011804:Quinolines; D010984:Platinum; C057812:indoline