title: Predominance and circulation of enteric viruses in the region of Greater Cairo, Egypt.
abstract: The circulation of enteric viruses among the population of Cairo, Egypt, between March 2006 and February 2007 was studied. At least one virus was detected in 50% of fecal samples, 57.4% of which were positive for rotavirus, 26% for norovirus, 10.4% for adenovirus, and 1.7% for astrovirus. Over 10% of infections were mixed infections. Rotavirus typing showed that G1P[8] and G2P[4] were predominant but that the unusual G12P[4] and G12P[6] reassortants were also present. Among the noroviruses, half belonged to the predominant GGII.4 cluster. The phylogenetic analysis of the capsid gene suggested that GGII.4 strains from Cairo were similar to those circulating elsewhere. It also showed the emergence of new GGII.4 variants that were not associated with any previously known GGII.4 isolate. Further studies are required to assess the disease burden of enteric viruses in Egypt and the impact of atypical strains.
authors.affiliation: Laboratory of Virology, National Reference Center for Enteric Viruses, Public Hospital of Dijon, Dijon, France.
authors.forename: Aziza H
authors.initials: AH
authors.lastname: Kamel
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Ali
authors.forename: Hala G
authors.initials: HG
authors.lastname: El-Nady
authors.forename: Alexis
authors.initials: A
authors.lastname: de Rougemont
authors.forename: Pierre
authors.initials: P
authors.lastname: Pothier
authors.forename: Gaël
authors.initials: G
authors.lastname: Belliot
mesh_terms: D000256:Adenoviridae / Q000235:genetics / Q000302:isolation & purification; D000293:Adolescent; D036022:Capsid Proteins / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D015897:Comorbidity; D004534:Egypt / Q000453:epidemiology; D004751:Enteritis / Q000453:epidemiology* / Q000821:virology*; D005243:Feces / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D001257:Mamastrovirus / Q000235:genetics / Q000302:isolation & purification; D008969:Molecular Sequence Data; D029322:Norovirus / Q000235:genetics / Q000302:isolation & purification; D010802:Phylogeny; D012401:Rotavirus / Q000235:genetics / Q000302:isolation & purification; D017422:Sequence Analysis, DNA; D014505:Urban Population; D014777:Virus Diseases / Q000453:epidemiology* / Q000821:virology*; D014780:Viruses / Q000145:classification* / Q000302:isolation & purification*
chemical_list: D036022:Capsid Proteins