title: First identification of metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Czech Republic.
abstract: Since 2005, invasive isolates of Pseudomonas aeruginosa have been collected in the Czech Republic as part of the European Antibiotic Resistance Surveillance System (EARSS). Forty-eight microbiology laboratories throughout the country including approximately 81% of the population provide consecutive isolates from blood and cerebrospinal fluid. Surprisingly, no metallo-beta-lactamase (MBL) was found in 1,259 invasive isolates tested over the past three years until the detection of two MBL-producing strains in mid-2008. Both strains were isolated from patients hospitalised in one regional hospital. The MBL was identified as IMP-7, which had been seen previously in Canada, Japan, Malaysia and Slovakia.
authors.affiliation: Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Hrabák
authors.forename: M
authors.initials: M
authors.lastname: Fridrichová
authors.forename: M
authors.initials: M
authors.lastname: Stolbová
authors.forename: T
authors.initials: T
authors.lastname: Bergerová
authors.forename: H
authors.initials: H
authors.lastname: Zemlickova
authors.forename: P
authors.initials: P
authors.lastname: Urbaskova
mesh_terms: D000328:Adult; D000368:Aged; D018153:Czech Republic; D005260:Female; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000201:enzymology* / Q000302:isolation & purification*; D013045:Species Specificity; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases; C524617:beta-lactamase IMP-7 protein, Pseudomonas aeruginosa