Spinal dural arteriovenous fistulas.
Spinal dural arteriovenous (AV) fistulas are the most commonly encountered vascular malformation of the spinal cord and a treatable cause for progressive para- or tetraplegia. They most commonly affect elderly men and are classically found in the thoracolumbar region. The AV shunt is located inside the dura mater close to the spinal nerve root where the arterial blood from a radiculomeningeal artery enters a radicular vein. The increase in spinal venous pressure leads to decreased drainage of normal spinal veins, venous congestion, and the clinical findings of progressive myelopathy. On MR imaging, the combination of cord edema, perimedullary dilated vessels, and cord enhancement is characteristic. Therapy has to be aimed at occluding the shunting zone, either by superselective embolization with a liquid embolic agent or by a neurosurgical approach. Following occlusion of the fistula, the progression of the disease can be stopped and improvement of symptoms is typically observed.
Krings
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Division of Neuroradiology, Department of Medical Imaging, University of Toronto, Toronto Western Hospital and Hospital for Sick Children, Toronto, Ontario, Canada. timo.krings@uhn.on.ca
Geibprasert
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D001164:Arteriovenous Fistula / Q000175:diagnosis* / Q000628:therapy*; D004388:Dura Mater / Q000098:blood supply; D004621:Embolization, Therapeutic; D006801:Humans; D013116:Spinal Cord / Q000098:blood supply; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000628:therapy*