title: Linkage disequilibrium and its expectation in human populations.
abstract: Abstract Linkage disequilibrium (LD), the association in populations between genes at linked loci, has achieved a high degree of prominence in recent years, primarily because of its use in identifying and cloning genes of medical importance. The field has recently been reviewed by Slatkin (2008). The present article is largely devoted to a review of the theory of LD in populations, including historical aspects.
authors.affiliation: School of Biological Sciences, University of Sydney, Australia. jsved@usyd.edu.au
authors.forename: John A
authors.initials: JA
authors.lastname: Sved
mesh_terms: D005828:Genetics, Population; D006801:Humans; D015810:Linkage Disequilibrium; D008957:Models, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics*