title: VANO: a volume-object image annotation system.
abstract: Volume-object annotation system (VANO) is a cross-platform image annotation system that enables one to conveniently visualize and annotate 3D volume objects including nuclei and cells. An application of VANO typically starts with an initial collection of objects produced by a segmentation computation. The objects can then be labeled, categorized, deleted, added, split, merged and redefined. VANO has been used to build high-resolution digital atlases of the nuclei of Caenorhabditis elegans at the L1 stage and the nuclei of Drosophila melanogaster's ventral nerve cord at the late embryonic stage.
  
  
  BACKGROUND
  Platform independent executables of VANO, a sample dataset, and a detailed description of both its design and usage are available at research.janelia.org/peng/proj/vano. VANO is open-source for co-development.
authors.affiliation: Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, VA, USA. pengh@janelia.hhmi.org
authors.forename: Hanchuan
authors.initials: H
authors.lastname: Peng
authors.forename: Fuhui
authors.initials: F
authors.lastname: Long
authors.forename: Eugene W
authors.initials: EW
authors.lastname: Myers
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000378:metabolism; D016208:Databases, Factual; D004330:Drosophila / Q000378:metabolism; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D012984:Software; D014584:User-Computer Interface