Seroprevalence of Toxoplasma gondii infection in Kwal, a rural distriction of Plateau-Nigeria.
Toxoplasma gondii infection has become a major public health concern in recent times due to the ravaging HIV/AIDS pandemic. The seroprevalence of T. gondii infection was determined in Kwal, a rural district of Plateau-Nigeria using IgG-ELISA. Epidemiological assessment was also conducted for the purpose of establishing the infection dynamics. Antibodies to T. gondii were detected in 30 (20.8%) of the 144 individuals studied. The prevalence of infection was slightly higher amongst the males (22.0%) than the females (20.0%), individuals of age group 21-30 years had the highest prevalence of 33.3% while the least (7.4%) occurred amongst the 41-50 years age group. No significant difference was noted (p < 0.05). The seroprevalence of Toxoplasma antibodies was significantly higher amongst individuals who handle/eat rodents (29.6%) and those who constantly had contact with soil (21.2%). These were the predominant risk factors of T. gondii infection in the area. Consequently, the infection occurred most amongst farmers (25.0%). This study contributes to the development of guidelines for the prevention and management of toxoplasmosis. Results were discussed in relation to the T. gondii epidemiological factors inherent within the population studied.
Uneke
C J
CJ
Department of Medical Microbiology/Parasitology, Faculty of Clinical Medicine, Ebonyi State University Teaching Hospital, Ebonyi, Nigeria.
Duhlinska
D D
DD
Ngwu
B A F
BA
Njoku
M O
MO
D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood* / Q000276:immunology; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D010265:Paraproteinemias; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G