title: Improved single-letter identification after whole-word training in pure alexia.
abstract: Pure alexia is characterised by a very time-consuming letter-by-letter reading strategy due to an impaired identification or integration of single letters. So far, therapy interventions have addressed impaired letter identification using specific single-letter training approaches. In the present study, we report patient KA with pure alexia and letter-by-letter reading. Contrary to common approaches, we investigated whether a whole-word reading approach can be successful despite severe impairments at the level of single-letter identification. As a first step, auditory-visual verification tasks were used to familiarise the patient with the training items, which in a second step were read with limited exposure duration. After a four week intervention, KA's word reading performance improved significantly for trained and control items in terms of speed and accuracy. Although not specifically addressed during our training programme, even single-letter identification and text reading performance increased significantly. However, the patient's reading was still based on a letter-by-letter strategy.
authors.affiliation: Department of Neurology, RWTH Aachen University Hospital, Aachen, Germany. iablinger@ukaachen.de
authors.forename: Irene
authors.initials: I
authors.lastname: Ablinger
authors.forename: Frank
authors.initials: F
authors.lastname: Domahs
mesh_terms: D020237:Alexia, Pure / Q000534:rehabilitation*; D006801:Humans; D007807:Language Tests; D007808:Language Therapy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D011930:Reaction Time; D011932:Reading; D021641:Recognition, Psychology; D014825:Vocabulary