title: [Historical evolution of some clinical and epidemiological knowledge of coccidioidomycosis in the Americas].
abstract: Coccidioidomycosis is a systemic endemic mycosis caused by two dimorphic fungi of the Coccidioides genus: Coccidioides immitis and Coccidioides posadasii. This fungal infection is only endemic in the American Continent. The majority of the epidemiological, pathogenic, clinical, mycological and therapeutical findings were obtained in the U.S.A. Coccidioidomycosis was discovered in Argentina, at the end of the XIXth century by Alejandro Posadas. In the last two decades, a new endemic zone was found in the northeast of Brazil. Several countries of the region such as Mexico, Guatemala, Honduras, Venezuela and Argentina have performed epidemiological studies which allowed a better knowledge of the endemic areas and of the clinical characteristics of this mycosis.
authors.affiliation: Centro de Micología, Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires,Ciudad Autónoma de Buenos Aires, Argentina. ricnegroni@hotmail.com
authors.forename: R
authors.initials: R
authors.lastname: Negroni
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000382:microbiology; D000569:Americas / Q000453:epidemiology; D003045:Coccidioides / Q000302:isolation & purification; D003047:Coccidioidomycosis / Q000453:epidemiology / Q000266:history*; D004196:Disease Outbreaks / Q000266:history; D019353:Endemic Diseases / Q000266:history*; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male