title: Stereoselective synthesis of novel highly substituted isochromanone and isoquinolinone-containing exocyclic tetrasubstituted alkenes.
abstract: An efficient synthetic route toward the synthesis of highly substituted arylethylidene-isoquinolinones/isochromanones is reported. The tandem carbopalladation/Suzuki-Miyaura coupling sequence stereoselectively provided various functionalized polycyclic compounds in moderate to excellent yields.
authors.affiliation: Institut Curie, Centre de Recherche, 26 rue d'Ulm, Paris F-75248 cedex 05, France.
authors.forename: Martin
authors.initials: M
authors.lastname: Arthuis
authors.forename: Renée
authors.initials: R
authors.lastname: Pontikis
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Florent
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D002867:Chromones; D007546:Isoquinolines