title: Acute stress cardiomyopathy following treatment of status asthmaticus.
abstract: Broken heart syndrome, otherwise known as takotsubo syndrome, is stress-induced cardiomyopathy. Clinical presentation mimics acute ST segment elevation myocardial infarction, but with characteristic left ventricular apical ballooning. The mechanism is linked to overstimulation of the sympathetic system from high circulating catecholamine levels. We report a 46-year-old Caucasian female whose treatment of status asthmaticus with ketamine and epinephrine precipitated this syndrome. She required hemodynamic support with an intra-aortic balloon pump and dobutamine infusion. Myocardial function improved dramatically with supportive treatment. Iatrogenically induced takotsubo syndrome with vasoactive agents should be suspected in acute left ventricular dysfunction without coronary artery disease.
authors.affiliation: Department of Medicine, Unity Health System, Rochester, NY 14626, USA. chinedu_f@yahoo.com
authors.forename: Ikenna
authors.initials: I
authors.lastname: Osuorji
authors.forename: Christina
authors.initials: C
authors.lastname: Williams
authors.forename: Joanne
authors.initials: J
authors.lastname: Hessney
authors.forename: Tejan
authors.initials: T
authors.lastname: Patel
authors.forename: David
authors.initials: D
authors.lastname: Hsi
mesh_terms: D000142:Acidosis, Respiratory; D000792:Angiography; D004562:Electrocardiography; D004837:Epinephrine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007649:Ketamine / Q000009:adverse effects*; D008875:Middle Aged; D013224:Status Asthmaticus / Q000150:complications*; D013315:Stress, Psychological / Q000150:complications; D054549:Takotsubo Cardiomyopathy / Q000139:chemically induced* / Q000175:diagnosis*; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D014662:Vasoconstrictor Agents; D007649:Ketamine; D004837:Epinephrine