title: Incompatibility between intravenous amiodarone and heparin in an infant.
abstract: Amiodarone is an effective antiarrhythmic agent and represents the drug of choice in the treatment of severe arrhythmias, especially in the setting of ventricular dysfunction. Amiodarone has the potential for interaction with many cardiac and non-cardiac drugs. Nonetheless few incompatibilities have been reported. We report the incompatibility between amiodarone and heparin administrated in the same vein in a case of a one month old baby with atrial flutter. This topic needs more attention, due to the frequent co-administration of these two drugs in tachyarrhythmias with high thromboembolic risk.
authors.affiliation: Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy. Electronic address: gabronz@hotmail.com.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Bronzetti
authors.affiliation: Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy.
authors.forename: Cinzia
authors.initials: C
authors.lastname: D'Angelo
authors.affiliation: Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Mariucci
authors.affiliation: Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy.
authors.forename: Fernando Maria
authors.initials: FM
authors.lastname: Picchio
authors.affiliation: Institute of Cardiology, University of Bologna, Azienda Ospedaliera S.Orsola-Malpighi, Bologna, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Boriani
mesh_terms: D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D001282:Atrial Flutter / Q000139:chemically induced* / Q000175:diagnosis*; D004347:Drug Interactions; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous
chemical_list: D006493:Heparin; D000638:Amiodarone