title: Catalytic Staudinger-Vilarrasa reaction for the direct ligation of carboxylic acids and azides.
abstract: 2,2'-Dipyridyl diselenide (PySeSePy) is the catalyst or activator of choice for the direct reaction of carboxylic acids with azides and trimethylphosphine at room temperature. The mechanism of the process, which is not an aza-Wittig reaction, has been elucidated.
authors.affiliation: Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, 08028 Barcelona, Catalonia, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Burés
authors.forename: Manuel
authors.initials: M
authors.lastname: Martín
authors.forename: Fèlix
authors.initials: F
authors.lastname: Urpí
authors.forename: Jaume
authors.initials: J
authors.lastname: Vilarrasa
mesh_terms: D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives* / Q000737:chemistry; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D001386:Azides / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; D001386:Azides; D002264:Carboxylic Acids; D016566:Organoselenium Compounds; D015082:2,2'-Dipyridyl; C012945:2,2'-dipyridyl diselenide