C-Graft in regeneration of periodontal tissue in intrabony periodontal defect in dog.
The aim of this study was to investigate the effect of C-Graft particles on formation of new cementum and bone in periodontal bone defects in dog. Healing and tissue change were histologically determined at 2, 4, 8, and 16 weeks. Little bone or cementum formation was observed in the control group. A statistically significant increase in bone and cementum formation was seen in the C-Graft group compared to the control group (75.4% vs. 44.9%, p < 50.01, 80.4% vs. 46.7%, p < 50.05, respectively). These findings suggest that C-Graft particles provide a scaffold for the regeneration of new bone and cementum.
Nakanishi
Shinsuke
S
Department of Periodontology, Tokyo Dental College, 1-2-2, Masago Mihama-ku, Chiba-shi, Chiba PREF261-8502, Japan. nakanishis@tdc.ac.jp
Ota
Mikio
M
Shibukawa
Yoshihiro
Y
Yamada
Satoru
S
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001861:Bone Regeneration; D003739:Dental Cementum / Q000473:pathology; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal; D006882:Hydroxyapatites / Q000737:chemistry / Q000627:therapeutic use*; D008297:Male; D008855:Microscopy, Electron, Scanning; D010519:Periodontium / Q000293:injuries* / Q000473:pathology; D016062:Porosity; D013997:Time Factors
D006882:Hydroxyapatites; C116586:fluorohydroxyapatite; D000469:Alkaline Phosphatase