Fanconi anemia complicated by neutropenic enterocolitis.
BACKGROUND
Neutropenic enterocolitis (NEC) also known as typhlitis is an acute, life-threatening inflammation of the small and large bowel often seen in patients with leukaemia undergoing cytotoxic chemotherapy: occasionally this syndrome could present in other immunocompromised patients.


OBJECTIVE
To report an unusual case of Fanconi anemia complicated by neutropenic enterocolitis.


METHODS
We report a case of a 13-year-old boy affected by Fanconi anemia with severe neutropenia and who presented neutropenic enterocolitis. Abdominal ultrasonography showed thickening of cecum and ascending colon of 1.18cm. The outcome was favourable with medical management.


CONCLUSIONS
Neutropenic enterocolitis in Fanconi anemia is a rare and a severe illness: however, the outcome is improved with early management.
Tinsa
Faten
F
Department of Pediatrics B, Children's Hospital of Tunis, Tunis, Tunisia.
Necib
Nesrine
N
Guesmi
Manef
M
Bousnina
Olfa
O
Douira
Wiem
W
Bousetta
Khadija
K
Bousnina
Souad
S
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001803:Blood Transfusion; D002442:Ceftazidime / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D044504:Enterocolitis, Neutropenic / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005199:Fanconi Anemia / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005839:Gentamicins; D008795:Metronidazole; D002442:Ceftazidime