Bovine tuberculosis in cattle and badgers in localized culling areas.
Bovine tuberculosis (TB) is a zoonotic disease that can have serious consequences for cattle farming and, potentially, for public health. In Britain, failure to control bovine TB has been linked to persistent infection of European badger (Meles meles) populations. However, culling of badgers in the vicinity of recent TB outbreaks in cattle has failed to reduce the overall incidence of cattle TB. Using data from a large-scale study conducted in 1998-2005, we show that badgers collected on such localized culls had elevated prevalence of Mycobacterium bovis, the causative agent of bovine TB, suggesting that infections in cattle and badgers were indeed associated. Moreover, there was a high degree of similarity in the M. bovis strain types isolated from cattle and associated badgers. This similarity between strain types appeared to be unaffected by time lags between the detection of infection in cattle and culling of badgers, or by the presence of purchased cattle that might have acquired infection elsewhere. However, localized culling appeared to prompt an increase in the prevalence of M. bovis infection in badgers, probably by disrupting ranging and territorial behavior and hence increasing intraspecific transmission rates. This elevated prevalence among badgers could offset the benefits, for cattle, of reduced badger densities and may help to explain the failure of localized culling to reduce cattle TB incidence.
Woodroffe
Rosie
R
Department of Wildlife, Fish & Conservation Biology, University of California, One Shields Avenue, Davis, California 95616, USA. rosie.woodroffe@ioz.ac.uk
Donnelly
Christl A
CA
Cox
D R
DR
Gilks
Peter
P
Jenkins
Helen E
HE
Johnston
W Thomas
WT
Le Fevre
Andrea M
AM
Bourne
F John
FJ
Cheeseman
C L
CL
Clifton-Hadley
Richard S
RS
Gettinby
George
G
Hewinson
R Glyn
RG
McInerney
John P
JP
Mitchell
A P
AP
Morrison
W Ivan
WI
Watkins
Gavin H
GH
D000818:Animals; D002417:Cattle; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary*; D004197:Disease Reservoirs / Q000382:microbiology / Q000662:veterinary; D005260:Female; D015994:Incidence; D008297:Male; D045969:Mustelidae / Q000382:microbiology*; D009163:Mycobacterium bovis / Q000302:isolation & purification; D011155:Population Control / Q000379:methods*; D012307:Risk Factors; D014380:Tuberculosis, Bovine / Q000453:epidemiology* / Q000635:transmission*; D006113:United Kingdom