title: The origin of the Japanese race based on genetic markers of immunoglobulin G.
abstract: This review addresses the distribution of genetic markers of immunoglobulin G (Gm) among 130 Mongoloid populations in the world. These markers allowed the populations to be clearly divided into 2 groups, the northern and southern groups. The northern group is characterized by high frequencies of 2 marker genes, ag and ab3st, and an extremely low frequency of the marker gene afb1b3; and the southern group, in contrast, is indicated by a remarkably high frequency of afb1b3 and low frequencies of ag and ab3st. Based on the geographical distribution of the markers and gene flow of Gm ag and ab3st (northern Mongoloid marker genes) from northeast Asia to the Japanese archipelago, the Japanese population belongs basically to the northern Mongoloid group and is thus suggested to have originated in northeast Asia, most likely in the Baikal area of Siberia.
authors.affiliation: Department of Legal Medicine, Osaka Medical College, Takatsuki City, Osaka, Japan. leg000@art.osaka-med.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Matsumoto
mesh_terms: D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics; D019143:Evolution, Molecular; D005787:Gene Frequency / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D005843:Geography; D006801:Humans; D007074:Immunoglobulin G / Q000235:genetics*; D007564:Japan
chemical_list: D005819:Genetic Markers; D007074:Immunoglobulin G