Palladium-catalyzed intramolecular hydroamination of allenes coupled to aerobic alcohol oxidation.
Taking the air! A Pd(II)-catalyzed intramolecular hydroamination of allenes coupled to alcohol oxidation has been developed. This reaction is performed by using a nitrogen-based ligand under aerobic conditions, under which the molecular oxygen is used as the terminal oxidant for the reoxidation of Pd(0) species to complete the catalytic cycle.
Qiu
Shuifa
S
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academic of Science, 354 Fengling Road, Shanghai, 200032, China.
Wei
Yunyang
Y
Liu
Guosheng
G
D000438:Alcohols / Q000737:chemistry*; D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D005680:gamma-Aminobutyric Acid
D000438:Alcohols; D000466:Alkadienes; C025947:propadiene; D005680:gamma-Aminobutyric Acid; D010165:Palladium; D009584:Nitrogen; D010100:Oxygen