Degradable nanogels as a nanoreactor for growing silica colloids.
Degradable nanogels with cleavable disulfide bonds were designed and used as a catalytic template, providing an alkali microenvironment. Well-defined hybrid silica colloids could be obtained by hydrolyzing tetraethyl orthosilicate (TEOS) in the nanogels. The size of silica colloids was found to be dependent on the size of the nanogels. After the removal of nanogels through reduction with 1,4-dithiothreitol (DTT), mesoporous silica colloids with a rough surface were obtained. The mesoporous structure of the colloids after reduction was characterized by transmission electron microscopy (TEM), surface area analysis, and X-ray diffraction (XRD). This work also provides an effective route for the preparation of mesoporous silica nanostructures, which may find wide applications as catalyst templates and drug carriers.
Li
Yong-Yong
YY
Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
Yang
Jie
J
Wu
Wei-Bing
WB
Zhang
Xian-Zheng
XZ
Zhuo
Ren-Xi
RX
D003102:Colloids / Q000737:chemistry; D003538:Cystamine / Q000031:analogs & derivatives / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D000080385:Nanogels; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
D003102:Colloids; D000080385:Nanogels; C413692:polyethylene glycol polyethyleneimine nanogel; D011092:Polyethylene Glycols; C027747:N,N'-bisacrylylcystamine; D012822:Silicon Dioxide; D011094:Polyethyleneimine; D003538:Cystamine