Reducing the rates of indeterminate results of the QuantiFERON-TB Gold In-Tube test during routine preemployment screening for latent tuberculosis infection among healthcare personnel.
We implemented the QuantiFERON-TB Gold (QFT-G) In-Tube test to identify latent tuberculosis infection among potential employees prior to employment. The rates of indeterminate QFT-G In-Tube test results were higher than expected and prompted an investigation that led to successful interventions (eg, manual vortexing before incubation and the use of a modified in-tube method). The tracking of indeterminate results is suggested as an important quality control measure.
Miranda
Cyndee
C
Department of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA. mirandc@ccf.org
Yen-Lieberman
Belinda
B
Terpeluk
Paul
P
Tomford
J Walton
JW
Gordon
Steven
S
D003955:Diagnostic Tests, Routine / Q000379:methods / Q000592:standards*; D006282:Health Personnel; D006801:Humans; D018570:Risk Assessment; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014374:Tuberculin Test / Q000379:methods / Q000592:standards*; D014376:Tuberculosis / Q000097:blood / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission