title: Cardiac tamponade: a rare complication of idiopathic hypereosinophilic syndrome.
abstract: Idiopathic hypereosinophilic syndrome (IHES) is a rare systemic disease with multiple clinical presentations including cardiac, pulmonary and dermatologic manifestations. Little is known about the pathophysiology and potential triggers of this condition. Approximately 40-70% of these cases have cardiac involvement, which is the major cause of morbidity and mortality. Cardiac tamponade is a rare but serious complication of IHES. Herein, we report a patient with IHES who presented with cardiac tamponade. To the authors' knowledge, this is the second case of cardiac tamponade in adults with IHES reported in the medical literature.
authors.affiliation: Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, USA. Antonio.fernandez@yale.edu
authors.forename: Antonio B
authors.initials: AB
authors.lastname: Fernandez
authors.forename: Shafeeq
authors.initials: S
authors.lastname: Ahmed
authors.forename: Brett
authors.initials: B
authors.lastname: Duncan
authors.forename: Stephen
authors.initials: S
authors.lastname: Firshein
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Kluger
mesh_terms: D000368:Aged; D001706:Biopsy; D002305:Cardiac Tamponade / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004452:Echocardiography; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D010490:Pericardial Effusion / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D010493:Pericarditis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D010496:Pericardium / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D011241:Prednisone; D006918:Hydroxyurea