Magnetoliposomes: versatile innovative nanocolloids for use in biotechnology and biomedicine.
The high biocompatibility and versatile nature of liposomes have made these particles keystone components in many hot-topic biomedical research areas. Liposomes can be combined with a large variety of nanomaterials, such as superparamagnetic iron oxide nanocores. Because the unique features of both the magnetizable colloid and the versatile lipid bilayer can be joined, the resulting so-called magnetoliposomes can be exploited in a great array of biotechnological and biomedical applications. In this article, we highlight the use of magnetoliposomes in immobilizing enzymes, both water-soluble and hydrophobic ones, as well as their potential in several biomedical applications, including MRI, hyperthermia cancer treatment and drug delivery. The goal of this article is not to list all known uses of magnetoliposomes but rather to present some conspicuous applications in comparison to other currently used nanoparticles.
Soenen
Stefaan J H
SJ
Interdisciplinary Research Centre, Laboratory of BioNanoColloids, KU Leuven-Campus Kortrijk, E Sabbelaan 53, B-8500 Kortrijk, Belgium.
Hodenius
Michael
M
De Cuyper
Marcel
M
D001709:Biotechnology / Q000379:methods*; D016503:Drug Delivery Systems; D008081:Liposomes / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*
D008081:Liposomes