title: Oxiranyl anion methodology using microflow systems.
abstract: Deprotonation of epoxides followed by trapping with electrophiles was carried out using microflow systems with varying temperature and residence time. Time-dependence of the yields of products provides a deeper insight into chemical and configurational stabilities of oxiranyllithiums. With the thus-obtained information, reactions of oxiranyllithiums with various electrophiles were successfully carried out without decomposition and isomerization.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.
authors.forename: Aiichiro
authors.initials: A
authors.lastname: Nagaki
authors.forename: Eiji
authors.initials: E
authors.lastname: Takizawa
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Yoshida