Comparison of the susceptibilities of clinical isolates of Candida albicans and Candida dubliniensis to essential oils.
Here, a microdilution technique based on the M27-A2 protocol (NCCLS, 2002) was employed to compare the susceptibilities of Candida albicans and Candida dubliniensis to essential oils extracted from plants used as spices. The chemical compositions of the essential oils were defined based on the analysis of retention indices obtained by gas chromatography-mass spectroscopy. Taken together, the results showed that the activity of the compounds against the two species was similar.
Pozzatti
Patrícia
P
Pharmaceutical Sciences Postgraduate Program, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Loreto
Erico Silva
ES
Lopes
Paulo Guilherme Markus
PG
Athayde
Margareth Linde
ML
Santurio
Janio Morais
JM
Alves
Sydney Hartz
SH
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D009822:Oils, Volatile; D010936:Plant Extracts