title: [Early fetal megacystis at first trimester: a six-year retrospective study].
abstract: OBJECTIVE
  A fetal megacystis is defined by a longitudinal bladder diameter more than 7 mm. The purpose of this study is to describe the prenatal ultrasound findings of this early fetal pathology and to assess pronostic and aetiologycal criteria.
  
  
  METHODS
  Between January 2003 and December 2008, 12 cases of early fetal megacystis were identified in our referral fetal medicine unit (Saint-Etienne hospital, France).
  
  
  RESULTS
  There were two cases of spontaneous resolution and one case wasn't a fetal megacystis. Termination of pregnancy for medical indications was realised for another cases because of associated malformations and bad evolution (six cases) and three chromosomal abnormalities (two cases of trisomy 18 and one of trisomy 21).
  
  
  CONCLUSIONS
  Sonographic follow-up and fetal karyotyping are important to evaluate prognosis. However, our data suggest that fetal megacystis is a severe condition when diagnosed in early pregnancy.
authors.affiliation: Service de gynécologie-obstétrique, CHU de Saint-Etienne, hôpital Nord, avenue Albert-Raimond, 42055 Saint-Etienne cedex 02, France.
authors.forename: K
authors.initials: K
authors.lastname: Boissier
authors.forename: M-N
authors.initials: MN
authors.lastname: Varlet
authors.forename: C
authors.initials: C
authors.lastname: Chauleur
authors.forename: S
authors.initials: S
authors.lastname: Cochin
authors.forename: A
authors.initials: A
authors.lastname: Clemenson
authors.forename: F
authors.initials: F
authors.lastname: Varlet
authors.forename: E
authors.initials: E
authors.lastname: Bellicard
authors.forename: C
authors.initials: C
authors.lastname: Chantegret
authors.forename: H
authors.initials: H
authors.lastname: Patural
authors.forename: P
authors.initials: P
authors.lastname: Seffert
authors.forename: G
authors.initials: G
authors.lastname: Chêne
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D005865:Gestational Age; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D014314:Trisomy; D016216:Ultrasonography, Prenatal / Q000379:methods*; D001743:Urinary Bladder / Q000002:abnormalities* / Q000000981:diagnostic imaging*