[Effects of surgical ovariectomy on dopamine receptors of the heart and brain].
In female rat experiment menopause was induced by surgical ovariectomy. It is shown that false ovariectomy decreases affinity and density of dopamine receptors in the heart and brain. Surgical ovariectomy contributes to an increase in the affinity of the heart dopamine receptors as well as affinity and density of the brain dopamine receptors. Changes in density and affinity of dopamine receptors in the heart and brain of rats after surgical ovariectomy evidence for involvement of dopaminergic system in pathogenesis of menopausal syndrome.
Kharchilava
O M
OM
Valeeva
L A
LA
D000818:Animals; D001921:Brain / Q000378:metabolism*; D005260:Female; D008593:Menopause / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010052:Ovariectomy; D051381:Rats; D011954:Receptors, Dopamine / Q000378:metabolism*; D013577:Syndrome
D011954:Receptors, Dopamine