An efficient copper-catalyzed oxidative Mannich reaction between tertiary amines and methyl ketones.
An efficient oxidative Mannich reaction between tertiary amines and unmodified methyl ketones has been developed, using copper salts as the catalyst and O(2) as the oxidant.
Shen
Youming
Y
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.
Li
Mo
M
Wang
Sizhuo
S
Zhan
Tianguang
T
Tan
Ze
Z
Guo
Can-Cheng
CC
D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008352:Mannich Bases / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000588:Amines; D008352:Mannich Bases; D003300:Copper