Bisbenzimidazole to benzobisimidazole: from binding B-form duplex DNA to recognizing different modes of telomere G-quadruplex.
A bisbenzimidazole was discovered to bind helix DNA, while related benzobisimidazole derivatives were found to bind and induce different G-quadruplex isomers.
Huang
Jing
J
College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, P. R. China.
Li
Guorui
G
Wu
Zhiguo
Z
Song
Zhibin
Z
Zhou
Yangyang
Y
Shuai
Liang
L
Weng
Xiaocheng
X
Zhou
Xiang
X
Yang
Guangfu
G
D001562:Benzimidazoles / Q000737:chemistry*; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D054856:G-Quadruplexes; D007093:Imidazoles / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D016615:Telomere / Q000737:chemistry*
D001562:Benzimidazoles; D007093:Imidazoles; D004247:DNA