title: Autoimmune angioneurotic edema in a patient with Helicobacter pylori infection.
abstract: Association of acquired autoimmune angioneurotic edema with other diseases is increasing. However, the precise mechanism by which antibodies to C1-esterase inhibitor (C1-INH) are produced, is not elucidated. We describe a patient with IgA antibodies against C1-INH without other autoimmune markers. Our patient had gastritis and Helicobacter pylori infection, proven by biopsy. This case suggests that H. pylori infection can act as triggering factor for acquired autoimmune angioneurotic edema.
authors.affiliation: Department of Internal Medicine and Infectious Diseases, Centre Hospitalier Universitaire, Liege, Belgium.
authors.forename: Didier
authors.initials: D
authors.lastname: Mukeba
authors.forename: Kavitha
authors.initials: K
authors.lastname: Chandrikakumari
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Giot
authors.forename: Philippe
authors.initials: P
authors.lastname: Leonard
authors.forename: Christelle
authors.initials: C
authors.lastname: Meuris
authors.forename: Frederic
authors.initials: F
authors.lastname: Frippiat
authors.forename: Michel
authors.initials: M
authors.lastname: Moutschen
mesh_terms: D000799:Angioedema / Q000209:etiology* / Q000276:immunology*; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D050718:Complement C1 Inhibitor Protein / Q000276:immunology; D005756:Gastritis / Q000150:complications / Q000382:microbiology; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D050718:Complement C1 Inhibitor Protein; D007070:Immunoglobulin A