A breast fibroadenoma mimicking an extranodal deposit of Hodgkin's lymphoma in 67Ga imaging.
We present the case of a young woman with classical nodular sclerosing Hodgkin's lymphoma (clinical stage IIB). During staging work-up, intense gallium-67 ((67)Ga) accumulation in a left breast lump raised the suspicion of an extranodal deposit, but biopsy favoured a benign histology. A post-treatment (67)Ga scan showed complete remission of the disease with normal tracer uptake in the left breast. However, a few months after treatment, a faint left mammary concentration of (67)Ga was observed. The breast mass was excised and histopathology was consistent with fibroadenoma. This unusual presentation is a new addition to the literature on false-positive (67)Ga findings and chemotherapy-associated tracer changes.
Moralidis
E
E
Department of Nuclear Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece. emoral@hol.gr
Mandala
E
E
Venizelos
I
I
Arsos
G
G
Zafiriadu
E
E
Goutzioulis
M
M
Karakatsanis
C
C
D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D003287:Contrast Media; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005710:Gallium Radioisotopes; D006689:Hodgkin Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D008207:Lymphatic Metastasis; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
D003287:Contrast Media; D005710:Gallium Radioisotopes