title: [Particularities of the association of systemic arterial hypertension in patients with sleep apnea syndrome].
abstract: OBJECTIVE
  Analysis of the association between sleep apnea syndrome (SAS) and systemic hypertension (SHT) in consecutive patients with suspicion of SAS.
  
  
  METHODS
  We included 427 consecutive patients evaluated for SAS at Babes University Sleep Lab, Timisoara (March 2001-March 2007). Medical history, anthropometric measurements, cardiovascular evaluation, inclusion/exclusion criteria, Epworth scale, polysomnography, statistical analysis with STATA 9.2. were done.
  
  
  RESULTS
  Systemic hypertension (SHT) at 245 (58,05%) of patients, pre-SHT at 11,37%, stage I 11,37%, stage II 29,14%, stage III 6,16%, onset of disease 7,26 +/- 6,13 years. Differences between groups without and with SHT: apnea-hypopnea index (AHI) 27,71 +/- 27,94/h, CI 23,55-31,78 vs 38,6 +/- 26,16/h, CI 35,34-41,85, p < 0,001, body mass index (BMI) 31,43 +/- 6,26 kg/m2, CI 30,50-32,36 vs 34,21 +/- 6,11 kg/m2, CI 33,45- 34,97 p < 0,001, desaturation index 20,21 +/- 26,35/h, CI 16,28-24,13 vs 31,12 +/- 29,16 CI 27,49-34,75, p < 0,001, medium desaturation 92,93 +/- 5,03%, CI 92,18-93,68 vs. 90,6 +/- 8,42, CI 89,55-91,64, p < 0,001, medium age 47,66 +/- 12,57 years, CI 45,79-49,52 vs. 55,06 +/- 10,35 years, CI 53,77-56,35, p = 0,0047, abdominal circumference 117,77 +/- 15,44 cm, CI 115,48-120,06 vs. 121,68 +/- 14,66 cm, CI 119,85-123,51, p = 0,0082, neck circumference 42,98 +/- 4,84 cm, CI 42,26-43,70 vs. 44,24 +/- 4.59 cm, CI 43,67-44,81 p = 0,0068, Epworth score 9,09 +/- 4,81, CI 8,37-9,80 vs. 10,77 +/- 5,19, CI 10,12-11,42, p = 0,007.
  
  
  CONCLUSIONS
  SHT represents the most frequent disease association in SAS patients. Differences between groups without and with SHT were statistical significant in apnea--hypopnea index, body mass index, desaturation index, medium desaturation, age, abdominal circumference, neck circumference, Epworth score.
authors.affiliation: Clinica de Pneumologie, UMF V. Babeş Timişoara. mihaicuta@yahoo.com
authors.forename: Stefan
authors.initials: S
authors.lastname: Mihăicuţă
authors.forename: Sorin
authors.initials: S
authors.lastname: Ursoniu
authors.forename: Daniel
authors.initials: D
authors.lastname: Lighezan
authors.forename: Danina
authors.initials: D
authors.lastname: Muntean
authors.forename: Ovidiu
authors.initials: O
authors.lastname: Firă-Mlădinescu
authors.forename: Raul
authors.initials: R
authors.lastname: Horhat
authors.forename: Stefan
authors.initials: S
authors.lastname: Frenţ
authors.forename: Dan
authors.initials: D
authors.lastname: Gaiţă
authors.forename: Voicu
authors.initials: V
authors.lastname: Tudorache
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000886:Anthropometry; D015992:Body Mass Index; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000175:diagnosis*
chemical_list: D010100:Oxygen