title: Nickel-catalyzed borylative coupling of alkynes, enones, and bis(pinacolato)diboron as a route to substituted alkenyl boronates.
abstract: Three-component coupling reactions of an alkyne, an enone, and a diboron reagent provide access to highly substituted alkenyl boronates in good to excellent yields (see scheme). The coupling is highly regio- and stereoselective, and the products are amenable to further functional-group transformations. R(1),R(2) = H, alkyl, aryl, CO(2)Me; R(3) = alkyl, Ph; R(4),R(5) = H, alkyl.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Mannathan
authors.forename: Masilamani
authors.initials: M
authors.lastname: Jeganmohan
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng