title: Balancing out the ends during iPSC nuclear reprogramming.
abstract: In this issue of Cell Stem Cell, Marion et al. (2009) report that efficient production of iPSCs requires active telomerase, which allows the rejuvenation of telomeres to a state similar to that observed in embryonic stem cells, even in iPSCs generated from old donor cells.
authors.affiliation: Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96183, USA.
authors.forename: Phil
authors.initials: P
authors.lastname: Davy
authors.forename: Richard
authors.initials: R
authors.lastname: Allsopp
mesh_terms: D000818:Animals; D065150:Cellular Reprogramming / Q000502:physiology*; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008954:Models, Biological; D039904:Pluripotent Stem Cells / Q000502:physiology*; D019098:Telomerase / Q000378:metabolism*; D016615:Telomere / Q000378:metabolism*
chemical_list: D019098:Telomerase