Neurocognitive predictors of financial capacity across the dementia spectrum: Normal aging, mild cognitive impairment, and Alzheimer's disease.
Financial capacity is a complex instrumental activity of daily living critical to independent functioning of older adults and sensitive to impairment in patients with amnestic mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, little is known about the neurocognitive basis of financial impairment in dementia. We developed cognitive models of financial capacity in cognitively healthy older adults (n = 85) and patients with MCI (n = 113) and mild AD (n = 43). All participants were administered the Financial Capacity Instrument (FCI) and a neuropsychological test battery. Univariate correlation and multiple regression procedures were used to develop cognitive models of overall FCI performance across groups. The control model (R2 = .38) comprised (in order of entry) written arithmetic skills, delayed story recall, and simple visuomotor sequencing. The MCI model (R2 = .69) comprised written arithmetic skills, visuomotor sequencing and set alternation, and race. The AD model (R2 = .65) comprised written arithmetic skills, simple visuomotor sequencing, and immediate story recall. Written arithmetic skills (WRAT-3 Arithmetic) was the primary predictor across models, accounting for 27% (control model), 46% (AD model), and 55% (MCI model) of variance. Executive function and verbal memory were secondary model predictors. The results offer insight into the cognitive basis of financial capacity across the dementia spectrum of cognitive aging, MCI, and AD.
Sherod
Megan G
MG
Department of Neurology, University of Alabama at Birmingham, 35294-0017, USA.
Griffith
H Randall
HR
Copeland
Jacquelynn
J
Belue
Katherine
K
Krzywanski
Sara
S
Zamrini
Edward Y
EY
Harrell
Lindy E
LE
Clark
David G
DG
Brockington
John C
JC
Powers
Richard E
RE
Marson
Daniel C
DC
D000368:Aged; D000375:Aging; D000544:Alzheimer Disease / Q000503:physiopathology* / Q000523:psychology; D000704:Analysis of Variance; D001288:Attention; D003072:Cognition Disorders / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D005376:Financial Management; D015577:Geriatric Assessment; D006801:Humans; D007802:Language; D008297:Male; D008433:Mathematics; D008568:Memory; D008606:Mental Processes / Q000502:physiology*; D008875:Middle Aged; D008960:Models, Psychological; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D014796:Visual Perception / Q000502:physiology