Methyl 5-glucosyl-5,6-dihydro-apo-4,4'-lycopenoate, a novel antioxidative glyco-C(30)-carotenoic acid produced by a marine bacterium Planococcus maritimus [corrected].
Planococcus maritimus strain iso-3 was isolated from an intertidal sediment sample from the Clyde estuary in the UK. A novel red pigment glyco-carotenoic acid ester, methyl glucosyl-3,4-dehydro-apo-8'-lycopenoate has been isolated from this marine bacterium using chromatographic methods. The structure of methyl glucosyl-3,4-dehydro-apo-8'-lycopenoate was determined to be methyl 1-(beta-D-glucopyranosyloxy)-3,4-didehydro-1,2-dihydro-8'-apo-psi-caroten-8'-oate by the degradation experiment and the spectroscopic analyses. The methyl glucosyl-3,4-dehydro-apo-8'-lycopenoate showed potent antioxidative activity in the (1)O(2) suppression model.
Shindo
Kazutoshi
K
Department of Food and Nutrition, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo 112-8681, Japan. kshindo@fc.jwu.ac.jp
Endo
Megumi
M
Miyake
Yuriko
Y
Wakasugi
Kyoko
K
Morritt
David
D
Bramley
Peter M
PM
Fraser
Paul D
PD
Kasai
Hiroaki
H
Misawa
Norihiko
N
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D002338:Carotenoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019015:Geologic Sediments / Q000382:microbiology*; D006094:Gram-Positive Bacteria / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism*; D020128:Inhibitory Concentration 50; D010802:Phylogeny; D010860:Pigments, Biological / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017382:Reactive Oxygen Species / Q000037:antagonists & inhibitors; D013057:Spectrum Analysis; D006113:United Kingdom
D000975:Antioxidants; D010860:Pigments, Biological; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D017382:Reactive Oxygen Species; D002338:Carotenoids