Prophylaxis of travel-related thrombosis in women.
Travel-related thrombosis occurs in 1/6,000 individuals who fly long-haul flights. The risk is increased significantly in passengers with thrombophilia and during hormonal therapy. Pregnancy is a hypercoagulable state with 5-10-fold increase in VTE risk. Mechanisms for hypercoagulation on air are related to cabin atmospheric conditions, with immobility and flight duration playing a major role. Prophylactic measures include frequent exercise in all passengers, elastic stockings and LMWH in travelers at high risk.
Brenner
Benjamin
B
Thrombosis & Haemostasis Unit, Rambam - Faculty of Medicine, Technion, Haifa, Israel. b_brenner@rambam.health.gov.il
D000401:Aircraft; D003681:Dehydration / Q000150:complications / Q000517:prevention & control; D004326:Drinking; D015444:Exercise; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D000860:Hypoxia / Q000150:complications; D007103:Immobilization / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology / Q000517:prevention & control; D018570:Risk Assessment; D053828:Stockings, Compression; D013927:Thrombosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D014195:Travel
D006495:Heparin, Low-Molecular-Weight