title: Intermolecular double Prins-type cyclization: a facile and efficient synthesis of 1,6-dioxecanes.
abstract: Double or nothing: The title reaction converts a range of aromatic aldehydes and allenylmethyl/allyl silanes into 1,6-dioxecane derivatives in good to excellent yields (see scheme; Ar = aryl, Tf = triflate, THF = tetrahydrofuran, TMS = trimethylsilyl). In addition, the bisdiene product has been transformed into the corresponding tricyclic compound through a Diels-Alder reaction.
authors.affiliation: Center for Chemoinformatics Research, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul 130-650, South Korea.
authors.forename: Punna Reddy
authors.initials: PR
authors.lastname: Ullapu
authors.forename: Sun-Joon
authors.initials: SJ
authors.lastname: Min
authors.forename: Satish N
authors.initials: SN
authors.lastname: Chavre
authors.forename: Hyunah
authors.initials: H
authors.lastname: Choo
authors.forename: Jae Kyun
authors.initials: JK
authors.lastname: Lee
authors.forename: Ae Nim
authors.initials: AN
authors.lastname: Pae
authors.forename: Youseung
authors.initials: Y
authors.lastname: Kim
authors.forename: Moon Ho
authors.initials: MH
authors.lastname: Chang
authors.forename: Yong Seo
authors.initials: YS
authors.lastname: Cho
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry
chemical_list: D000447:Aldehydes; D006571:Heterocyclic Compounds; D012821:Silanes