Two methods for attenuating Toxoplasma gondii tachyzoites RH strain by using ethanol extract of Curcuma longa.
The ethanol extract of Curcuma longa proved to be an attenuated agent against Toxoplasma gondii (RH strain) tachyzoites in the mice peritoneal fluid by two incubation methods. Groups of female mice were injected by attenuated tachyzoites as 200 tachyzoites / ml, which treated with the ethanol extract of Curcuma longa was previously treated. The result was observed after one week, as no tachyzoites were found in the peritoneal fluid of the experimental infected mice.
Al-Zanbagi
Najia A
NA
Department of Biology, Zoology Section, College of Science, King Abdulaziz University, P.O. Box 42626, Jeddah 21551, Saudi Arabia.
Zelai
Nuha T
NT
D000818:Animals; D030024:Curcuma / Q000737:chemistry*; D004195:Disease Models, Animal; D000431:Ethanol; D005260:Female; D008018:Life Cycle Stages / Q000187:drug effects*; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D014122:Toxoplasma / Q000187:drug effects* / Q000254:growth & development* / Q000472:pathogenicity; D014124:Toxoplasmosis, Animal / Q000517:prevention & control*; D014611:Vaccination; D014774:Virulence
D010936:Plant Extracts; D000431:Ethanol