title: The dilated aorta in patients with congenital cardiac defects.
abstract: Many patients with congenital cardiac disease are at risk for progressive aortic dilation. The mechanisms underlying aortic dilation in this patient cohort are described, and the similarities to the pathophysiologic alterations seen in Marfan syndrome are highlighted. Indications for treatment are discussed.
authors.affiliation: Adult Congenital Cardiology Program, Department of Pediatrics and Medicine, Division of Cardiology, Primary Children's Medical Center, The University of Utah, Salt Lake City, UT 84108, USA. Angela.Yetman@imail.org
authors.forename: Anji T
authors.initials: AT
authors.lastname: Yetman
authors.forename: Thomas
authors.initials: T
authors.lastname: Graham
mesh_terms: D001018:Aortic Diseases / Q000209:etiology* / Q000503:physiopathology*; D004108:Dilatation, Pathologic; D006330:Heart Defects, Congenital / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D008382:Marfan Syndrome / Q000503:physiopathology*; D016212:Transforming Growth Factor beta
chemical_list: D016212:Transforming Growth Factor beta