title: Role of dietary intervention and nutritional follow-up in heart transplant recipients.
abstract: BACKGROUND
  Obesity, dyslipidemia, hypertension, and diabetes mellitus are common features after heart transplantation and they lead to coronary artery disease and graft loss.
  
  
  OBJECTIVE
  To determine the effects of a dietary intervention on nutritional status and metabolic outcome of two groups enrolled during or after the first year from the transplant.
  
  
  METHODS
  Forty two subjects (mean age 51.36+/-12.4 yr) were studied; 20 were enrolled during the first year by the transplant, 22 were enrolled after the first year from the transplant (7.9+/-3.86 and 56.86+/-38.6 months after surgery, respectively). According to diet compliance both groups were divided into two subgroups and they were prospectively followed for 4 years. Anthropometric measurements, biochemical nutritional markers, and dietary records were collected at baseline (T0) and after a 12-month follow-up period (T12) and a 48-month follow-up period (T48). Body composition was performed at T0 and T12.
  
  
  RESULTS
  Diet compliance was associated with a decrease in total cholesterol, triglycerides and glucose plasma level and with a weight loss mainly due to a decrease in fat mass.
  
  
  CONCLUSIONS
  Our study shows the efficacy of dietary intervention to obtain an early and late weight and metabolic control after heart transplant.
authors.affiliation: Department of Neuroscience, Physiology Nutrition Unit, University Federico II of Naples, Naples, Italy. bguida@unina.it
authors.forename: Bruna
authors.initials: B
authors.lastname: Guida
authors.forename: Nunzia Ruggiero
authors.initials: NR
authors.lastname: Perrino
authors.forename: Roberta
authors.initials: R
authors.lastname: Laccetti
authors.forename: Rossella
authors.initials: R
authors.lastname: Trio
authors.forename: Annamaria
authors.initials: A
authors.lastname: Nastasi
authors.forename: Domenica
authors.initials: D
authors.lastname: Pesola
authors.forename: Ciro
authors.initials: C
authors.lastname: Maiello
authors.forename: Claudio
authors.initials: C
authors.lastname: Marra
authors.forename: Luca Salvatore
authors.initials: LS
authors.lastname: De Santo
authors.forename: Maurizio
authors.initials: M
authors.lastname: Cotrufo
mesh_terms: D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D004032:Diet; D005260:Female; D005500:Follow-Up Studies; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000178:diet therapy*; D008875:Middle Aged; D015596:Nutrition Assessment; D010349:Patient Compliance; D011446:Prospective Studies; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss
chemical_list: D014280:Triglycerides; D002784:Cholesterol