title: Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
authors.affiliation: Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.
authors.forename: Alice E
authors.initials: AE
authors.lastname: Chen
authors.forename: Dieter
authors.initials: D
authors.lastname: Egli
authors.forename: Kathy
authors.initials: K
authors.lastname: Niakan
authors.forename: Jie
authors.initials: J
authors.lastname: Deng
authors.forename: Hidenori
authors.initials: H
authors.lastname: Akutsu
authors.forename: Mariko
authors.initials: M
authors.lastname: Yamaki
authors.forename: Chad
authors.initials: C
authors.lastname: Cowan
authors.forename: Claire
authors.initials: C
authors.lastname: Fitz-Gerald
authors.forename: Kun
authors.initials: K
authors.lastname: Zhang
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Melton
authors.forename: Kevin
authors.initials: K
authors.lastname: Eggan
mesh_terms: D000818:Animals; D053624:Blastocyst Inner Cell Mass / Q000166:cytology / Q000502:physiology*; D000071616:CDX2 Transcription Factor; D018929:Cell Culture Techniques; D002460:Cell Line; D002478:Cells, Cultured; D016000:Cluster Analysis; D053595:Embryonic Stem Cells / Q000502:physiology*; D020869:Gene Expression Profiling; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D050814:Octamer Transcription Factor-3 / Q000235:genetics / Q000378:metabolism
chemical_list: D000071616:CDX2 Transcription Factor; C491270:CDX2 protein, human; D018398:Homeodomain Proteins; D050814:Octamer Transcription Factor-3; C494173:POU5F1 protein, human