Quantitative phase imaging of nanoscale cell structure and dynamics.
Quantitative phase imaging (QPI) of live cells has received significant scientific interest over the past decade or so, mainly because it offers structure and dynamics information at the nanometer scale in a completely noninvasive manner. We present recent developments of QPI technology both for full-field and point measurements. Their applications are classified into static and dynamic according to their temporal selectivity. Several promising prospects are discussed in the summary section.
Popescu
Gabriel
G
Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
D002462:Cell Membrane / Q000378:metabolism; D002465:Cell Movement; D049109:Cell Proliferation; D048429:Cell Size; D002477:Cells / Q000166:cytology* / Q000648:ultrastructure*; D004912:Erythrocytes / Q000166:cytology; D005583:Fourier Analysis; D006367:HeLa Cells; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D012031:Refractometry