title: Synthesis, characterization, biological activities of dimethyltin(IV) complexes of Schiff bases with ONO-type donors.
abstract: Four different dimethyltin(IV) complexes of Schiff bases derived from 2-amino-3-hydroxypyridine and different substituted salicylaldehydes have been synthesized. The compounds, with the general formula [Me(2)Sn(2-OArCH=NC(5)H(3)NO)], where Ar=-C(6)H(3)(5-CH(3)) [Me(2)SnL(1)], -C(6)H(3)(5-NO(2)) [Me(2)SnL(2)], -C(6)H(2)(3,5-Cl(2)) [Me(2)SnL(3)], and -C(6)H(2)(3,5-I(2)) [Me(2)SnL(4)], were characterized by IR, NMR ((1)H and (13)C), mass spectroscopy and elemental analysis. Me(2)SnL(3) was also characterized by X-ray diffraction analysis and shows a fivefold C(2)NO(2) coordination with distorted square pyramidal geometry. H(3)C-Sn-CH(3) angles in the complexes were calculated using Lockhart's equations with the (1)J((117/119)Sn-(13)C) and (2)J((117/119)Sn-(1)H) values (from the (1)H-NMR and (13)C-NMR spectra). The in vitro antibacterial and antifungal activities of dimethyltin(IV) complexes were also investigated.
authors.affiliation: Department of Chemistry, Faculty of Science, Hacettepe University, 06800, Ankara, Turkey.
authors.forename: Nurşen Altuntaş
authors.initials: NA
authors.lastname: Oztaş
authors.forename: Gülgün
authors.initials: G
authors.lastname: Yenişehirli
authors.forename: Nilgün
authors.initials: N
authors.lastname: Ancin
authors.forename: Selma Gül
authors.initials: SG
authors.lastname: Oztaş
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Ozcan
authors.forename: Semra
authors.initials: S
authors.lastname: Ide
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009947:Organotin Compounds / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D011725:Pyridines / Q000737:chemistry; D012545:Schiff Bases / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D000447:Aldehydes; D009947:Organotin Compounds; D011725:Pyridines; D012545:Schiff Bases; C014047:hydroxypyridines; C013243:salicylaldehyde; C039760:dimethyltin