Rhodium(I)-catalyzed enantioselective C-C bond activation.
Relieving the strain: The rhodium(I)-catalyzed activation of C-C bonds in functionalized cyclobutanes opens a novel route to highly substituted carbo- and heterocycles. Particularly intriguing is the differentiation of enantiotopic C-C bonds, which leads to the formation of highly enantiomerically enriched lactones, cyclopentanones, and cyclohexenones (see scheme).
Winter
Christian
C
Organic Chemistry, Dortmund University of Technology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
Krause
Norbert
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