[New therapeutic strategy for mitochondrial diseases].
Mitochondrial diseases have a peculiar character of variability that expands from DNA, cell and tissue/organ levels to family/society level. These kinds of variability seem an obstacle to prevent us from developing new and effective therapies for this disease. Selective delivery system to mitochondria can make us get a promising new strategy to treat and prevent the disease. MITO-Porter may be a powerful system in which we can introduce a various kind of materials including DNA, RNA, enzyme and drugs to mitochondria in vivo.
Goto
Yu-ichi
Y
National Institute of Neuroscience, NCNP.
D016503:Drug Delivery Systems; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D008081:Liposomes; D028361:Mitochondrial Diseases / Q000628:therapy*
D008081:Liposomes