Severe triple vessel coronary artery disease and aneurysms in a young white man: disease progression of childhood Kawasaki disease.
Kawasaki disease usually affects younger age groups, but cardiac sequelae of 'missed' (incomplete) childhood Kawasaki disease may first present in adult life. We report a case of a 28-year-old white man presenting with ST elevation myocardial infarction and later found to have triple vessel coronary artery aneurysmal disease, probably secondary to childhood Kawasaki disease for which he underwent cardiac bypass surgery. The patient has remained well and asymptomatic at 1-year follow-up. This case is highlighted as the incidence of Kawasaki disease is relatively low among the white population, and yet there are increasing reports of adult patients presenting with coronary artery aneurysmal disease secondary to childhood Kawasaki disease. There has been a relative paucity of reports of surgical revascularization for adult survivors of childhood Kawasaki disease. This report also emphasizes the importance of early recognition and aggressive treatment of the often missed, incomplete, form of Kawasaki disease, which may reduce the risk of late development of coronary artery aneurysms. There should be a high index of suspicion of Kawasaki disease in young adults presenting with aneurysmal coronary artery disease with no significant coronary risk factors and in the absence of generalized atherosclerosis.
Sivalingam
Senthil K
SK
Department of Internal Medicine, Baystate Medical Center, Tufts University, Massachusetts, USA. senthikumar_mmc@yahoo.com
Parthasarathy
Hari K
HK
Choong
Cliff K
CK
Freeman
Leisa J
LJ
D000328:Adult; D003323:Coronary Aneurysm / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D018450:Disease Progression; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000473:pathology / Q000601:surgery; D009203:Myocardial Infarction / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D012720:Severity of Illness Index; D016896:Treatment Outcome