title: Determination of normal human intrathyroidal iodine in Caracas population.
abstract: This study focuses on the determination of iodine content in healthy thyroid samples on male population from Caracas, Venezuela. Contribution to establish a baseline of iodine content in thyroid glands and hence to compare the iodine thyroid concentration of the Venezuelan population with other countries is also our objective. Male post-mortem individual samples were analyzed using a spectrophotometric flow injection method, based on the Sandell-Kolthoff reaction. The median intrathyroidal iodine concentration was 1443+/-677 microg/g (wet weight), ranging from 419 to 3430 microg/g, which corresponds to a median of total iodine content of 15+/-8 mg (ranging from 4 to 37). These results were higher than those values reported in the literature. No correlation of iodine content with age or weight of the healthy gland was found.
authors.affiliation: Analytical Chemistry Center, School of Chemistry, Faculty of Science, Central University of Venezuela, P.O. Box 40764, Caracas 1053, Venezuela.
authors.forename: José
authors.initials: J
authors.lastname: Zabala
authors.forename: Nereida
authors.initials: N
authors.lastname: Carrión
authors.forename: Miguel
authors.initials: M
authors.lastname: Murillo
authors.forename: Mercedes
authors.initials: M
authors.lastname: Quintana
authors.forename: José
authors.initials: J
authors.lastname: Chirinos
authors.forename: Nelly
authors.initials: N
authors.lastname: Seijas
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Duarte
authors.forename: Peter
authors.initials: P
authors.lastname: Brätter
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D007455:Iodine / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D044382:Population Groups; D013053:Spectrophotometry; D013961:Thyroid Gland / Q000737:chemistry*; D014687:Venezuela
chemical_list: D007455:Iodine