title: A simple model for exploring conformation of highly-charged electrosprayed single-stranded oligonucleotides.
abstract: The study of the maximum charge state versus the molecular weight of single-stranded polynucleotides analyzed by electrospray reveals that single strands adopt a compact conformation in positive ion mode, whereas linear structures are predominant in negative ion mode.
authors.affiliation: Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland.
authors.forename: David
authors.initials: D
authors.lastname: Touboul
authors.forename: Renato
authors.initials: R
authors.lastname: Zenobi
mesh_terms: D000465:Algorithms; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D009841:Oligonucleotides