title: Pertussis outbreak in primary and secondary schools in Ludwigslust, Germany demonstrating the role of waning immunity.
abstract: A pertussis outbreak primarily affecting school-age children in Ludwigslust, Germany, was investigated in 2006 to estimate attack rates and relative risk of pertussis according to time since last vaccination, after a complete primary course. Results suggested waning immunity beginning approximately 5 years after the last dose of pertussis vaccination. Most cases could have been prevented by earlier booster vaccination.
authors.affiliation: Field Epidemiology Training Program, Robert Koch Institute, Berlin, Germany.
authors.forename: Muna Abu
authors.initials: MA
authors.lastname: Sin
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Zenke
authors.forename: Rita
authors.initials: R
authors.lastname: Rönckendorf
authors.forename: Martina
authors.initials: M
authors.lastname: Littmann
authors.forename: Pernille
authors.initials: P
authors.lastname: Jorgensen
authors.forename: Wiebke
authors.initials: W
authors.lastname: Hellenbrand
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D001886:Bordetella pertussis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004196:Disease Outbreaks; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007109:Immunity / Q000276:immunology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010567:Pertussis Vaccine / Q000276:immunology; D012307:Risk Factors; D012574:Schools; D014611:Vaccination / Q000706:statistics & numerical data; D014917:Whooping Cough / Q000453:epidemiology* / Q000276:immunology* / Q000382:microbiology / Q000635:transmission; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine