title: [A case of sarcoidosis with pleural involvement but with no mediastinal or hilar lymph node enlargement].
abstract: A 66-year-old woman was referred to our hospital because of right chest pain on inspiration. Chest X-ray film revealed diffuse opacities, predominantly in the lower lung field, and right pleural thickening. Serum ACE and lysozyme levels were elevated. Chest CT revealed diffuse ground-glass opacity, centrilobular granular nodules, bronchovascular bundle irregular thickening and right pleural irregular thickening over the right inferior lobe, but bilateral hilar lymph node enlargement was not present. Bronchoalveolar lavage (BAL) fluid demonstrated increased numbers of total cells and CD4 T-helper lymphocytes. The transbronchial lung biopsy specimen revealed non-caseating epithelioid cell granulomas. From these findings, we established a diagnosis of type III sarcoidosis with pleural involvement. The patient has been observed without treatment, and 10 months later the lung involvement and pleural thickening have disappeared.
authors.affiliation: Department of Respiratory Medicine, Hiratsuka Kyosai Hospital.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kegasawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Saito
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ryujin
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Reo
authors.initials: R
authors.lastname: Hamaguchi
authors.forename: Hideyasu
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Akiko
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Yamazaki
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Jin
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Yoshimura
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ohtani
authors.forename: Naohiko
authors.initials: N
authors.lastname: Inase
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yoshizawa
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D010994:Pleura / Q000473:pathology*; D011859:Radiography; D012507:Sarcoidosis / Q000000981:diagnostic imaging / Q000473:pathology*