title: Pregnancy in classic galactosemia despite undetectable anti-Müllerian hormone.
abstract: OBJECTIVE
  To report a pregnancy in a patient with classic galactosemia despite signs of no ovarian reserve to draw attention to the limited predictive value of ovarian reserve tests in these patients.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Secondary and tertiary care center.
  
  
  METHODS
  A patient with classic galactosemia with premature ovarian failure and two previous pregnancies.
  
  
  METHODS
  Exogenous FSH ovarian reserve test and anti-Müllerian hormone (AMH) measurement.
  
  
  METHODS
  17beta-Estradiol response, AMH level.
  
  
  RESULTS
  Pregnancy despite undetectable AMH (<0.1 microg/L) and no E(2) response (exogenous FSH ovarian reserve test).
  
  
  CONCLUSIONS
  Fluctuating premature ovarian failure makes fertility counseling of patients with classic galactosemia difficult. Commonly used ovarian function and reserve tests seem to have no significance.
authors.affiliation: Department of Pediatrics, Maastricht University Medical Center, Maastricht, The Netherlands.
authors.forename: Cynthia S
authors.initials: CS
authors.lastname: Gubbels
authors.forename: Simone M I
authors.initials: SM
authors.lastname: Kuppens
authors.forename: Jaap A
authors.initials: JA
authors.lastname: Bakker
authors.forename: Constantijn J A M
authors.initials: CJ
authors.lastname: Konings
authors.forename: K Will
authors.initials: KW
authors.lastname: Wodzig
authors.forename: Monique G M
authors.initials: MG
authors.lastname: de Sain-van der Velden
authors.forename: Paul P
authors.initials: PP
authors.lastname: Menheere
authors.forename: M Estela
authors.initials: ME
authors.lastname: Rubio-Gozalbo
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000032:analysis* / Q000097:blood; D003940:Diagnostic Techniques, Endocrine; D005260:Female; D005693:Galactosemias / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D020073:Gravidity; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000175:diagnosis*; D016649:Primary Ovarian Insufficiency / Q000097:blood / Q000175:diagnosis / Q000209:etiology
chemical_list: D054304:Anti-Mullerian Hormone