title: [A case of non small cell lung cancer associated with multiple cerebral infarctions due to nonbacterial thrombotic endocarditis].
abstract: A 67-year-old woman was admitted to our hospital for weakness in her right hand. MRI showed multiple cerebral infarctions and ultrasonic cardiography revealed vegetation on her aortic valve, so embolic stroke was diagnosed. Though she was afebrile and her vital signs were normal, chest CT revealed several enlarged mediastinal lymph nodes and a small nodule in the left lower lobe of the lung. Stage III adenocarcinoma of the lung was diagnosed, and the cause of her cerebral infarctions was found to be nonbacterial thrombotic endocarditis (NBTE). NBTE is known as the cause of embolic stroke among patients with advanced cancer, particularly adenocarcinoma. Prompt initiation of continuous heparin administration is required to interrupt the progress of cerebral thromboembolism in NBTE. In cases of coexisting cancer and embolic stroke, we should consider the possibility of NBTE.
authors.affiliation: Department of Respiratory Medicine, Seirei Mikatahara Hospital.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Oyama
authors.forename: Koshi
authors.initials: K
authors.lastname: Yokomura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsuda
authors.forename: Hideki
authors.initials: H
authors.lastname: Kusagaya
authors.forename: Hideki
authors.initials: H
authors.lastname: Yasui
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsui
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Nakano
authors.forename: Takafumi
authors.initials: T
authors.lastname: Suda
authors.forename: Kingo
authors.initials: K
authors.lastname: Chida
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D002544:Cerebral Infarction / Q000209:etiology*; D004696:Endocarditis / Q000150:complications*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D013927:Thrombosis / Q000150:complications*