Post-transcriptional gene regulation: RNA-protein interactions, RNA processing, mRNA stability and localization.
The goal of our workshop is to introduce some recent work in the area of post-transcriptional regulation to a wider computational community, discuss some of the unique computational problems faced in this area, and to present some preliminary solutions to these problems. In particular, we will focus on emerging computational and large-scale experimental strategies (e.g. microarray and deep sequencing) for investigating aspects of gene regulation at the post-transcriptional level, with an emphasis on the identification and characterization of the cis- and trans-acting RNA and protein components involved. We will also be exploring new developments in computational methods to detect and characterize cis-regulatory signals encoded in mRNAs.
Blencowe
Benjamin
B
Department of Molecular Genetics, University of Toronto, 1 King's College Rd., Toronto, ON, M5S 1A8, Canada.
Brenner
Steven
S
Hughes
Timothy
T
Morris
Quaid
Q
D001699:Biometry; D003627:Data Interpretation, Statistical; D030541:Databases, Genetic; D030562:Databases, Protein; D006801:Humans; D008957:Models, Genetic; D012323:RNA Processing, Post-Transcriptional; D020871:RNA Stability; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
D012333:RNA, Messenger; D016601:RNA-Binding Proteins