[Advances of BMSCs in tumor therapy].
OBJECTIVE
To review researches of BMSCs in tumor therapy.


METHODS
The recent relevant literature was extensively reviewed. The tropism of BMSCs to cancer, the effect of BMSCs on tumor growth and the application of BMSCs in tumor therapy were summarized.


RESULTS
BMSCs has the tropism to tumor and may inhibit or enhance growth of tumor. BMSCs as gene-delivery vehicle for gene therapy had obtained certain therapeutic efficacy. However, BMSCs can become tumorigenic.


CONCLUSIONS
BMSCs is a good gene-delivery vehicle for gene therapy. The relationship of BMSCs and tumor cells should be studied deeply for enhance the safety of BMSCs in gene therapy of tumor.
Luo
Jingcong
J
Division of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R. China.
Yang
Zhiming
Z
D001854:Bone Marrow Cells; D006801:Humans; D009369:Neoplasms / Q000628:therapy*