title: Optimizing trial design: sequential, adaptive, and enrichment strategies.
authors.affiliation: Cytel Statistical Software and Services, 675 Massachusetts Ave, Cambridge, MA 02139, USA. mehta@cytel.com
authors.forename: Cyrus
authors.initials: C
authors.lastname: Mehta
authors.forename: Ping
authors.initials: P
authors.lastname: Gao
authors.forename: Deepak L
authors.initials: DL
authors.lastname: Bhatt
authors.forename: Robert A
authors.initials: RA
authors.lastname: Harrington
authors.forename: Simona
authors.initials: S
authors.lastname: Skerjanec
authors.forename: James H
authors.initials: JH
authors.lastname: Ware
mesh_terms: D054058:Acute Coronary Syndrome / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D002986:Clinical Trials as Topic / Q000379:methods* / Q000592:standards*; D006801:Humans; D015233:Models, Statistical