title: [Malignant thyroid neoplasms: a diagnostic challenge for ENT specialists].
abstract: BACKGROUND
  Thyroid carcinoma is frequently diagnosed incidentally during routine ENT examinations.
  
  
  METHODS
  Symptoms and clinical findings of 40 patients with thyroid malignancies presenting in our department were analysed retrospectively. The aim was to define characteristics indicative for the final diagnosis of thyroid malignancy.
  
  
  RESULTS
  In 48% the initial presentation was not because of thyroid-specific complaints, however during the course of the general ENT examination, unspecific thyroid pathology was detected and further evaluated using sonography, scintigraphy and fine needle biopsy (FNB). The results of scintigraphy were suspicious in 67% and FNB was positive in 30%, inconclusive in 30% and false negative in 40%. For suspected malignancies a rapid frozen section examination was carried out which was positive only in 60% and false negative or inconclusive in 20% each.
  
  
  CONCLUSIONS
  Thyroid lesions incidentally found during ENT examination should undergo ultrasound examination, FNB and scintigraphy with the clear understanding that there is no single diagnostic feature leading to the correct diagnosis and that only the synopsis of various findings and sometimes only final histology leads to the correct diagnosis.
authors.affiliation: Hals-, Nasen-, Ohrenklinik und Poliklinik, Johannes-Gutenberg-Universität, Mainz, Deutschland. fruth@hno.klinik.uni-mainz.de
authors.forename: K
authors.initials: K
authors.lastname: Fruth
authors.forename: W J
authors.initials: WJ
authors.lastname: Mann
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010036:Otolaryngology / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000175:diagnosis*