[Granulomatous liver disease as the presenting feature of alveolar echinococcosis in an hepatitis C infected cardiac transplant patient].
Alveolar echinococcosis (AE) is a rare but potentially serious zoonosis for which an early diagnosis is of primary importance. We report the first observation of AE in a cardiac transplant patient infected by hepatitis C virus. He first presented with a single asymptomatic hepatic nodule. The liver biopsy showed an epithelioid granuloma with necrosis. We review the clinical features, diagnosis and outcome of this disease in immunocompromised hosts. In immunocompromised patients living in areas endemic for Echinococcus multilocularis, AE should be included in the differential diagnosis of tumor like lesions of the liver.
Gaultier
J-B
JB
Service de médecine interne et de pathologie vasculaire, centre hospitalier Lyon-Sud, hospices civils de Lyon, chemin du grand-Revoyet, 69495 Pierre-Bénite, France. cjbgaultier@yahoo.com
Hot
A
A
Mauservey
C
C
Dumortier
J
J
Coppéré
B
B
Ninet
J
J
D000328:Adult; D000818:Animals; D001706:Biopsy; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology; D048210:Echinococcus multilocularis; D006099:Granuloma / Q000150:complications / Q000276:immunology* / Q000473:pathology; D016027:Heart Transplantation; D006526:Hepatitis C / Q000150:complications* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000150:complications / Q000276:immunology* / Q000473:pathology; D008297:Male; D009336:Necrosis; D015047:Zoonoses