title: Comparison of analytic and algebraic methods for motion-compensated cone-beam CT reconstruction of the thorax.
abstract: Respiratory motion is a major concern in cone-beam (CB) computed tomography (CT) of the thorax. It causes artifacts such as blur, streaks, and bands, in particular when using slow-rotating scanners mounted on the gantry of linear accelerators. In this paper, we compare two approaches for motion-compensated CBCT reconstruction of the thorax. The first one is analytic; it is heuristically adapted from the method of Feldkamp, Davis, and Kress (FDK). The second one is algebraic: the system of linear equations is generated using a new algorithm for the projection of deformable volumes and solved using the Simultaneous Algebraic Reconstruction Technique (SART). For both methods, we propose to estimate the motion on patient data using a previously acquired 4-D CT image. The methods were tested on two digital and one mechanical motion-controlled phantoms and on a patient dataset. Our results indicate that the two methods correct most motion artifacts. However, the analytic method does not fully correct streaks and bands even if the motion is perfectly estimated due to the underlying approximation. In contrast, the algebraic method allows us full correction of respiratory-induced artifacts.
authors.affiliation: Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.
authors.forename: Simon
authors.initials: S
authors.lastname: Rit
authors.forename: David
authors.initials: D
authors.lastname: Sarrut
authors.forename: Laurent
authors.initials: L
authors.lastname: Desbat
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D013902:Radiography, Thoracic / Q000379:methods*; D015656:Respiratory Mechanics / Q000502:physiology*