Adsorption properties of proteins on SBA-15 nanoparticles functionalized with aminosilanes.
Since the discovery of ordered mesoporous silica M41S in 1992, a variety of ordered mesoporous materials have been synthesized by using the template technique. In this work, aminosilane-modified SBA-15 nanoparticles were prepared by incorporating various aminosilanes on original SBA-15 via post synthesis method. These aminosilanes were 3-aminopropyltriethoxysilane, N-2(-aminoethyl)-3-aminopropyl trimethoxysilane and (3-trimethoxysilylpropyl)diethylenetriamine. The synthesized nanoparticles were characterized by XRD, SEM, TEM and FT-IR. Adsorption and release studies of bovine serum albumin (BSA), lysozyme and myoglobin on SBA-15 samples were investigated. It was found that the synthesized SBA-15 nanoparicles can be successfully applied in drug delivery system.
Lee
Jae-Wook
JW
Department of Chemical and Biochemical Engineering, Chosun University, Gwangju 501-759, Republic of Korea.
Tra
Pham Thi
PT
Kim
Sul-Il
SI
Roh
Sung-Hee
SH
D000327:Adsorption; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles; D011506:Proteins / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
D011506:Proteins; C509969:SBA-15; D012821:Silanes; D012822:Silicon Dioxide