title: Isolated sinonasal sarcoidosis with intracranial extension: case report.
abstract: The case is presented of a 20-year-old female who was incidentally diagnosed with isolated sarcoidosis in the form of a nasal mass involving the ethmoid sinuses with destruction of the cribriform plate and intracranial extension. The patient complained of cacosmia and nasal obstruction. Histopathologic examination of biopsies from the nasal mass led to a diagnosis of non-caseating granuloma, highly suggestive of sarcoidosis. No systemic manifestations were detected, and the patient was started on a regimen of systemic steroids. Over the 3 months following biopsy and commencement of systemic steroids, the patient showed improvement in symptoms, and computed tomography of the paranasal sinuses revealed complete resolution of the sinonasal mass. Follow-up for one year revealed no recurrence.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Ain Shams University, Cairo, Egypt. odessouky@gmail.com
authors.forename: O Y
authors.initials: OY
authors.lastname: Dessouky
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D015508:Nasal Obstruction / Q000209:etiology; D010254:Paranasal Sinus Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D010256:Paranasal Sinuses / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012507:Sarcoidosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011239:Prednisolone