title: Highly functional group tolerance in copper-catalyzed N-arylation of nitrogen-containing heterocycles under mild conditions.
abstract: A copper-catalyzed process has been developed for the N-arylation reaction under very mild conditions in the absence of additional ligand. This protocol could not only tolerate an array of thermally sensitive functional groups, but also achieve high chemoselectivity.
authors.affiliation: Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, People's Republic of China.
authors.forename: Liangbo
authors.initials: L
authors.lastname: Zhu
authors.forename: Gaocan
authors.initials: G
authors.lastname: Li
authors.forename: Liang
authors.initials: L
authors.lastname: Luo
authors.forename: Peng
authors.initials: P
authors.lastname: Guo
authors.forename: Jingbo
authors.initials: J
authors.lastname: Lan
authors.forename: Jingsong
authors.initials: J
authors.lastname: You
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D006571:Heterocyclic Compounds; D006846:Hydrocarbons, Halogenated; D003300:Copper; D009584:Nitrogen