High mortality among patients with AIDS who received a diagnosis of tuberculosis in the first 3 months of antiretroviral therapy.
We analyzed mortality among 201 patients with AIDS and tuberculosis in Haiti. Patients who received a diagnosis of tuberculosis during the first 3 months after the initiation of antiretroviral therapy were 3.25 times more likely to die than were other patients with AIDS and tuberculosis. Failure to recognize active tuberculosis at initiation of antiretroviral therapy leads to increased mortality.
Koenig
Serena P
SP
Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. skoenig@partners.org
Riviere
Cynthia
C
Leger
Paul
P
Joseph
Patrice
P
Severe
Patrice
P
Parker
Kea
K
Collins
Sean
S
Lee
Erin
E
Pape
Jean W
JW
Fitzgerald
Daniel W
DW
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006205:Haiti; D006801:Humans; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy* / Q000401:mortality*; D055815:Young Adult