title: In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots.
abstract: PEGylated quantum dots (QDs) capped with d-mannose, d-galactose, and d-galactosamine have been synthesized. The stable, high quantum yield fluorescence of QDs was exploited to study specific carbohydrate-protein interactions in vitro and in vivo.
authors.affiliation: Laboratory for Organic Chemistry, Swiss Federal Institute of Technology (ETH) Zurich, Wolfgang-Pauli-Str. 10, 8093 Zurich, Switzerland.
authors.forename: Raghavendra
authors.initials: R
authors.lastname: Kikkeri
authors.forename: Bernd
authors.initials: B
authors.lastname: Lepenies
authors.forename: Alexander
authors.initials: A
authors.lastname: Adibekian
authors.forename: Paola
authors.initials: P
authors.lastname: Laurino
authors.forename: Peter H
authors.initials: PH
authors.lastname: Seeberger
mesh_terms: D000818:Animals; D037263:Asialoglycoprotein Receptor / Q000378:metabolism; D045744:Cell Line, Tumor; D005434:Flow Cytometry; D005688:Galactosamine / Q000737:chemistry*; D005690:Galactose / Q000737:chemistry*; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008358:Mannose / Q000737:chemistry*; D051379:Mice; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D045663:Quantum Dots
chemical_list: D037263:Asialoglycoprotein Receptor; D011092:Polyethylene Glycols; D005688:Galactosamine; D008358:Mannose; D005690:Galactose