title: Long-term outcomes of dual kidney transplantation-a single center experience.
abstract: The shortage of kidney donors has led to broadening of the acceptance criteria for deceased donor organs beyond the traditional use of young donors. We determined long-term post-transplant outcomes in recipients of dual expanded criteria donor kidneys (dECD, n = 44) and compared them to recipients of standard criteria donor kidneys (SCD, n = 194) and single expanded criteria donor kidneys (sECD, n = 62). We retrospectively reviewed these 300 deceased donor kidney transplants without primary non-function (PNF) or death in the first two wk, at our center from 1996 to 2003. The three groups were similar in baseline characteristics. Kidney allograft survival and patient survival (nine yr) were similar in the three respective donor groups, SCD, sECD and dECD (60% vs. 59% vs. 64% and 82% vs. 73% vs. 73%). Acute rejection in the first three months was 23.2%, 16.1%, and 22.7% in SCD, sECD and dECD, respectively (p = 0.49) and delayed graft function was 25.2%, 31.9% and 17.1% in the three groups, respectively (p = 0.28). When PNF and death within the first two wk was included, there was no significant difference in graft survival between the three groups. In our population, recipients of dECD transplants have acceptable patient and graft survival with kidneys that would have usually been discarded.
authors.affiliation: Division of Nephrology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA. moro@salifu.net
authors.forename: Moro O
authors.initials: MO
authors.lastname: Salifu
authors.forename: Allen J
authors.initials: AJ
authors.lastname: Norin
authors.forename: Christine
authors.initials: C
authors.lastname: O'Mahony
authors.forename: Nabil
authors.initials: N
authors.lastname: Sumrani
authors.forename: Anatoly
authors.initials: A
authors.lastname: Apel
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ikram
authors.forename: Anis
authors.initials: A
authors.lastname: Alam
authors.forename: Amir
authors.initials: A
authors.lastname: Hayat
authors.forename: Rahul M
authors.initials: RM
authors.lastname: Jindal
authors.forename: Eli A
authors.initials: EA
authors.lastname: Friedman
authors.forename: Dale A
authors.initials: DA
authors.lastname: Distant
mesh_terms: D000328:Adult; D001741:Black or African American; D000368:Aged; D002102:Cadaver; D046148:Donor Selection; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult