title: Ruthenium-catalyzed amino- and alkoxycarbonylations with carbamoyl chlorides and alkyl chloroformates via aromatic C-H bond cleavage.
abstract: Ruthenium-catalyzed regioselective direct amino- and alkoxycarbonylations of aromatic rings via C-H bond cleavage using chlorocarbonyl compounds are described. A broad generality of amide and ester groups was achieved taking advantage of the wide availability of carbonylating agents. Alkyl chloroformates, inapplicable to usual Friedel-Crafts methods, can also be used for direct catalytic alkoxycarbonylation.
authors.affiliation: Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Kochi
authors.forename: Seiya
authors.initials: S
authors.lastname: Urano
authors.forename: Hajime
authors.initials: H
authors.lastname: Seki
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Mizushima
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Sato
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Kakiuchi