Determination of normal human intrathyroidal iodine in Caracas population.
This study focuses on the determination of iodine content in healthy thyroid samples on male population from Caracas, Venezuela. Contribution to establish a baseline of iodine content in thyroid glands and hence to compare the iodine thyroid concentration of the Venezuelan population with other countries is also our objective. Male post-mortem individual samples were analyzed using a spectrophotometric flow injection method, based on the Sandell-Kolthoff reaction. The median intrathyroidal iodine concentration was 1443+/-677 microg/g (wet weight), ranging from 419 to 3430 microg/g, which corresponds to a median of total iodine content of 15+/-8 mg (ranging from 4 to 37). These results were higher than those values reported in the literature. No correlation of iodine content with age or weight of the healthy gland was found.
Zabala
José
J
Analytical Chemistry Center, School of Chemistry, Faculty of Science, Central University of Venezuela, P.O. Box 40764, Caracas 1053, Venezuela.
Carrión
Nereida
N
Murillo
Miguel
M
Quintana
Mercedes
M
Chirinos
José
J
Seijas
Nelly
N
Duarte
Leopoldo
L
Brätter
Peter
P
D000293:Adolescent; D000328:Adult; D006801:Humans; D007455:Iodine / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D044382:Population Groups; D013053:Spectrophotometry; D013961:Thyroid Gland / Q000737:chemistry*; D014687:Venezuela
D007455:Iodine