title: [Acute fatty liver of pregnancy. "Incidence, pathogenesis, diagnosis, treatment and prognosis"].
abstract: Acute fatty liver of pregnancy (AFLP) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. It generally appears between weeks 30 and 38. Usually the APLF symptoms start one to two weeks before hospitalization with nausea, emesis, general uneasiness, jaundice, epigastric pain and other symptoms. A careful history and physical examination, in conjunction with compatible laboratory and imaging results, are often sufficient to make the diagnosis, and liver biopsy is rarely indicated. The maternal outcome has improved enormously during the last decade. Early diagnosis, pregnancy termination and handling in special care or treating complications has lead to good maternofetal results.
authors.affiliation: Service de Réanimation médicale CHU Habib Bourguiba Route el Ain Km 1 3029.
authors.forename: Mabrouk
authors.initials: M
authors.lastname: Bahloul
authors.forename: Hichem
authors.initials: H
authors.lastname: Ksibi
authors.forename: Nadia
authors.initials: N
authors.lastname: Khlaf Bouaziz
authors.forename: Hassan
authors.initials: H
authors.lastname: Dammak
authors.forename: Chokri
authors.initials: C
authors.lastname: Ben Hamida
authors.forename: Hatem
authors.initials: H
authors.lastname: Kallel
authors.forename: Hédi
authors.initials: H
authors.lastname: Chelly
authors.forename: Mounir
authors.initials: M
authors.lastname: Bouaziz
mesh_terms: D000208:Acute Disease; D042241:Early Diagnosis; D005234:Fatty Liver / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy; D011263:Pregnancy Trimester, Third; D011379:Prognosis; D012307:Risk Factors