Renal amyloidosis in juvenile rheumatoid arthritis.
We report a case of a rare disorder of renal amyloidosis occurring as a complication of juvenile rheumatoid arthritis in a 16-year-old adolescent male. He presented with generalized edema and hypertension. The laboratory work-up showed nephrotic-range proteinuria and hypoalbuminemia and normal renal function despite bilateral shrunken kidneys revealed by the abdominal ultrasound. His renal biopsy showed deposition of amyloid fibrils in the form of homogenous eosinophilic material within the glomeruli demonstrating the pathognomonic apple-green birefringence by polarized light microscopy.
Akhtar
Naureen
N
Department of Pediatric Nephrology, The Children's Hospital and Institute of Child Health, Lahore. naureenakhtar@hotmail.com
Kiran
Sadia
S
Hussain
Abid
A
Suleman
Bilquis A
BA
Jaleel
Shahila
S
D000293:Adolescent; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001171:Arthritis, Juvenile / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D011379:Prognosis