First identification of metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Czech Republic.
Since 2005, invasive isolates of Pseudomonas aeruginosa have been collected in the Czech Republic as part of the European Antibiotic Resistance Surveillance System (EARSS). Forty-eight microbiology laboratories throughout the country including approximately 81% of the population provide consecutive isolates from blood and cerebrospinal fluid. Surprisingly, no metallo-beta-lactamase (MBL) was found in 1,259 invasive isolates tested over the past three years until the detection of two MBL-producing strains in mid-2008. Both strains were isolated from patients hospitalised in one regional hospital. The MBL was identified as IMP-7, which had been seen previously in Canada, Japan, Malaysia and Slovakia.
Hrabák
J
J
Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic.
Fridrichová
M
M
Stolbová
M
M
Bergerová
T
T
Zemlickova
H
H
Urbaskova
P
P
D000328:Adult; D000368:Aged; D018153:Czech Republic; D005260:Female; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000201:enzymology* / Q000302:isolation & purification*; D013045:Species Specificity; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases; C524617:beta-lactamase IMP-7 protein, Pseudomonas aeruginosa