title: Enantioselective synthesis of tetrafluorinated ribose and fructose.
abstract: A perfluoroalkylidene lithium mediated cyclisation approach for the enantioselective synthesis of a tetrafluorinated aldose (ribose) and of a tetrafluorinated ketose (fructose), both in the furanose and in the pyranose form, is described.
authors.affiliation: School of Chemistry, University of Southampton, Highfield, Southampton, UK. bruno.linclau@soton.ac.uk
authors.forename: Bruno
authors.initials: B
authors.lastname: Linclau
authors.forename: A James
authors.initials: AJ
authors.lastname: Boydell
authors.forename: Roxana S
authors.initials: RS
authors.lastname: Timofte
authors.forename: Kylie J
authors.initials: KJ
authors.lastname: Brown
authors.forename: Victoria
authors.initials: V
authors.lastname: Vinader
authors.forename: Alexander C
authors.initials: AC
authors.lastname: Weymouth-Wilson
mesh_terms: D003500:Cyclization; D005461:Fluorine; D005632:Fructose / Q000031:analogs & derivatives / Q000138:chemical synthesis; D012266:Ribose / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D005461:Fluorine; D005632:Fructose; D012266:Ribose