Association study between B- and T-lymphocyte attenuator gene and type 1 diabetes mellitus or systemic lupus erythematosus in the Japanese population.
This study is to elucidate whether the B- and T-lymphocyte attenuator (BTLA) gene is a new susceptibility gene for the development of type 1 diabetes (T1D) and systemic lupus erythematosus (SLE). As a result, this study did not find any genetic contribution of the BTLA gene to the development of T1D and SLE in Japanese population.
Inuo
M
M
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan. mikam@pediatr.med.kyushu-u.ac.jp
Ihara
K
K
Matsuo
T
T
Kohno
H
H
Hara
T
T
D000483:Alleles; D001402:B-Lymphocytes / Q000378:metabolism; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011971:Receptors, Immunologic / Q000235:genetics*; D013601:T-Lymphocytes / Q000378:metabolism
C482586:BTLA protein, human; D011971:Receptors, Immunologic