[System analytical approach of lung function and hemodynamics].
The authors critically analyse the traditional views in physiology and complete them with new statements based on computer model simulations of lung function and of hemodynamics. Conclusions are derived for the clinical practice as follows: the four-dimensional function curves are similar in both systems; there is a "waterfall" zone in the pulmonary blood perfusion; the various time constants of pulmonary regions can modify the blood gas values; pulmonary capillary pressure is equal to pulmonary arterial diastole pressure; heart is not a pressure pump, but a flow source; ventricles are loaded by the input impedance of the arterial systems and not by the total vascular (ohmlike) resistance; optimum heart rate in rest depends on the length of the aorta; this law of heart rate, based on the principle of resonance is valid along the mammalian allometric line; tachycardia decreases the input impedance; using positive end expiratory pressure respirators the blood gas of pulmonary artery should be followed; coronary circulation should be assessed in beat per milliliter, the milliliter per minute may be false. These statements are compared to related references.
Naszlady
Attila
A
Budapest Sashegyi út 18. 1124. naszlady.attila@iif.hu
Kiss
Lajos
L
D001783:Blood Flow Velocity; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000503:physiopathology; D003326:Coronary Circulation; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D011175:Positive-Pressure Respiration; D012119:Respiration; D012143:Respiratory Physiological Phenomena; D012137:Respiratory System / Q000503:physiopathology; D013610:Tachycardia / Q000503:physiopathology; D014655:Vascular Resistance