A molecularly imprinted polymer-coated nanocomposite of magnetic nanoparticles for estrone recognition.
In this study, we synthesized Fe(3)O(4) magnetic nanoparticles coated estrone-imprinted polymer with controlled size using a semi-covalent imprinting strategy. In this protocol, the estrone-silica monomer complex (EstSi) was synthesized by the reaction 3-(triethoxysilyl)propyl isocyanate with estrone, where the template was linked to the silica coating on the iron oxide core via a thermally reversible bond. The removal of the template by a simple thermal reaction produced specific estrone recognition sites on the surface of silica shell.The resulting estrone-imprinted polymer coating Fe(3)O(4) magnetic hybrid nanoparticles exhibit a much higher specific recognition and saturation magnetization. The hybrid nanoparticles have been used for biochemical separation of estrone.
Wang
Xin
X
Department of Chemistry, Nankai University, Tianjin 300071, PR China.
Wang
Lianyan
L
He
Xiwen
X
Zhang
Yukui
Y
Chen
Langxing
L
D020099:Coated Materials, Biocompatible; D004970:Estrone / Q000032:analysis / Q000302:isolation & purification*; D005290:Ferric Compounds; D008280:Magnetics; D008722:Methods; D054802:Molecular Imprinting; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide
D020099:Coated Materials, Biocompatible; D005290:Ferric Compounds; C000499:ferric oxide; D004970:Estrone; D012822:Silicon Dioxide