title: Simplification of the research diagnosis of HIV-associated sensory neuropathy.
abstract: Peripheral neuropathy (PN) is the most common neurological complication of HIV infection,affecting over one third of patients. The research diagnosis of PN is complicated by the need for expensive, time-consuming, and noxious diagnostic tests. We investigated whether nerve conduction studies (NSC) and quantitative sensory tests (QST) provide added value for the diagnosis of PN for research purposes or whether the easily obtainable clinical measures (sensory and motor symptoms, sensitivity to pain and vibration, tendon reflexes, motor function) are sufficient.
authors.affiliation: Harvard School of Public Health, Boston, Massachusetts 02115, USA. evans@sdac.harvard.edu
authors.forename: Scott R
authors.initials: SR
authors.lastname: Evans
authors.forename: David B
authors.initials: DB
authors.lastname: Clifford
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Kitch
authors.forename: Karl
authors.initials: K
authors.lastname: Goodkin
authors.forename: Giovanni
authors.initials: G
authors.lastname: Schifitto
authors.forename: Justin C
authors.initials: JC
authors.lastname: McArthur
authors.forename: David M
authors.initials: DM
authors.lastname: Simpson
mesh_terms: D004594:Electrophysiology / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D009460:Neurologic Examination / Q000379:methods*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis*; D012678:Sensation Disorders / Q000175:diagnosis*; D012680:Sensitivity and Specificity