Majocchi's granuloma in a liver transplant recipient caused by a Trichophyton spp., phenotypically consistent with Trichophyton rubrum var. raubitschekii.
The authors report a case of Majocchi's granuloma and onychomycosis in a liver transplant recipient caused by a Trichophyton spp., phenotypically consistent with Trichophyton rubrum var. raubitschekii. A 48-year-old female patient who had undergone liver transplantation nine months earlier, presented with red papules and nodular lesions on her back, buttock and thigh of two months duration. She also had onychomycosis of toe nails for a few years, which worsened post transplant. Two fungal isolates were derived from her infected toe nails and nodular tissue. Physical, pathological and mycological examination, including KOH preparation, fungal culture and DNA sequencing of the internal transcribed spacer(ITS) of rRNA were performed. The clinical diagnosis was Majocchi's granuloma and onychomycosis caused by the Trichophyton rubrum var. raubitschekii. This is the first case report of this organism from China.
Ma
Lei
L
Department of Dermatology/Research Center for Medical Mycology, Peking University First Hospital, Beijing, PR China.
Li
Ruoyu
R
Yu
Jin
J
Wang
Chen
C
Wan
Zhe
Z
Wang
Xiaohong
X
D002681:China; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D005260:Female; D006099:Granuloma / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000382:microbiology* / Q000473:pathology; D008107:Liver Diseases / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D008875:Middle Aged; D014009:Onychomycosis; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D014005:Tinea / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D014180:Transplantation; D014249:Trichophyton / Q000145:classification* / Q000166:cytology / Q000302:isolation & purification* / Q000378:metabolism
D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer