title: Evolution of interventions for complex coronary lesions.
abstract: The exponential growth of percutaneous coronary intervention (PCI) has in large part been due to expansion of the indications to include the procedure in patients with extensive coronary disease, multiple risk factors, older age and comorbidities. Improvement in PCI equipment, development of new interventional techniques, and availability of myocardial and systemic support techniques have all contributed to this growth. With these advances, patients once considered high risk for PCI are no longer considered high risk. This article reviews the complex coronary lesions challenges, various interventional and pharmacologic strategies for optimal results and novel technology.
authors.affiliation: Department of Internal Medicine, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System Little Rock, AR, USA. RSachdeva@uams.edu
authors.forename: R
authors.initials: R
authors.lastname: Sachdeva
authors.forename: S
authors.initials: S
authors.lastname: Prayaga
authors.forename: D
authors.initials: D
authors.lastname: Bansal
authors.forename: S
authors.initials: S
authors.lastname: Bagwe
authors.forename: B
authors.initials: B
authors.lastname: Hughes
authors.forename: B
authors.initials: B
authors.lastname: Molavi
authors.forename: F
authors.initials: F
authors.lastname: Romeo
authors.forename: J L
authors.initials: JL
authors.lastname: Mehta
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D002986:Clinical Trials as Topic; D001026:Coronary Artery Bypass / Q000379:methods; D003324:Coronary Artery Disease / Q000473:pathology / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation; D015607:Stents; D016896:Treatment Outcome