title: Nodular melanoma presenting with rapid progression and widespread metastases: a case report.
abstract: BACKGROUND
  Melanoma is responsible for 1% to 2% of all cancer deaths around the world. Nodular melanoma often carries a poor prognosis because of no prodromal radial growth phase, early distant metastasis and significant tumor volume.
  
  
  METHODS
  We present a case of progressive melanoma. A 51-year-old man was admitted to our hospital with dyspnea and skin lesions. These were multiple, dark colored, firm, and nodular and varied in size. He was diagnosed with melanoma. Temozolomide was administered, but he died of respiratory failure within a week after diagnosis.
  
  
  CONCLUSIONS
  Nodular melanoma tends to spread rapidly and eventually metastasize to vital organs. It may be fatal within months of recognition.
authors.affiliation: Inonu University Faculty of Medicine, Department of Hematology, Turgut Ozal Medical Center, TR-44069 Malatya, Turkey. erkurtali@hotmail.com.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Erkurt
authors.forename: Ismet
authors.initials: I
authors.lastname: Aydogdu
authors.forename: Irfan
authors.initials: I
authors.lastname: Kuku
authors.forename: Emin
authors.initials: E
authors.lastname: Kaya
authors.forename: Yalcin
authors.initials: Y
authors.lastname: Basaran