Doxycycline-induced pseudotumor cerebri.
Tetracyclines are a commonly prescribed medication for the treatment of acne vulgaris that are associated with pseudotumor cerebri (PTC). With doxycycline specifically, however, the incidence of PTC is very rare. A patient was using oral doxycycline and topical retinoids for acne, and within two months she developed PTC. This case illustrates that despite the rarity of doxycycline-induced PTC, patients and physicians should be aware of this possibility. Furthermore, in the setting of new-onset headaches or visual changes, early ophthalmologic examination for papilledema is recommended for early diagnosis.
Tabibian
James H
JH
Division of Dermatology, Geffen School of Medicine at UCLA, Los Angeles, CA, USA. jhtabib@ucla.edu
Gutierrez
Miguel A
MA
D000152:Acne Vulgaris / Q000188:drug therapy; D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004318:Doxycycline / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D014212:Tretinoin / Q000008:administration & dosage; D055815:Young Adult
D000900:Anti-Bacterial Agents; D007641:Keratolytic Agents; D014212:Tretinoin; D004318:Doxycycline