title: Simultaneous pleomorphic adenoma of the parapharyngeal space and contralateral submandibular gland. Case report.
abstract: Herein the case is reported of a synchronous parapharyngeal space pleomorphic adenoma arising from the pharyngeal prolongation of the parotid gland and the contralateral submandibular gland, diagnosed in a young Caucasian female. Case reports and recent literature are presented. Upon physical examination, asymmetry of the lower part of the right side of the face with overlying intact skin, and a submucosal firm swelling, filling the ipsilateral side of the oropharyngeal wall, involving the right tonsillar bed which was medially displaced was immediately recognizable. The patient did not complain of dysphagia. Palpating the left submandibular region, a painless, mobile, rounded mass, 10 mm in diameter, apparently located in the submandibular gland, was detected. Magnetic resonance imaging showed that both lesions were well-defined and encapsulated. The surgical approach is discussed. Cytological diagnosis was that of a typical pleomorphic adenoma. To the best of our knowledge this is the second case report in the English literature of a concomitant pleomorphic adenoma located both in the parapharyngeal space and the submandibular gland.
authors.affiliation: Department of ORL, IRRCS "San Raffaele" Hospital, "Vita-Salute" University, Milan, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Pistorio
authors.forename: R
authors.initials: R
authors.lastname: Teggi
authors.forename: M
authors.initials: M
authors.lastname: Bussi
mesh_terms: D008949:Adenoma, Pleomorphic / Q000175:diagnosis; D000328:Adult; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D010307:Parotid Neoplasms / Q000175:diagnosis; D010614:Pharynx; D013365:Submandibular Gland Neoplasms / Q000175:diagnosis