title: IAPV, a bee-affecting virus associated with Colony Collapse Disorder can be silenced by dsRNA ingestion.
abstract: Colony Collapse Disorder (CCD) has been associated with Israeli acute paralysis virus (IAPV). CCD poses a serious threat to apiculture and agriculture as a whole, due to the consequent inability to provide the necessary amount of bees for pollination of critical crops. Here we report on RNAi-silencing of IAPV infection by feeding bees with double-stranded RNA, as an efficient and feasible way of controlling this viral disease. The association of CCD with IAPV is discussed, as well as the potential of controlling CCD.
authors.affiliation: Robert H. Smith Institute for Plant Sciences and Genetics in Agriculture, Virus Laboratory, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Maori
authors.forename: N
authors.initials: N
authors.lastname: Paldi
authors.forename: S
authors.initials: S
authors.lastname: Shafir
authors.forename: H
authors.initials: H
authors.lastname: Kalev
authors.forename: E
authors.initials: E
authors.lastname: Tsur
authors.forename: E
authors.initials: E
authors.lastname: Glick
authors.forename: I
authors.initials: I
authors.lastname: Sela
mesh_terms: D000818:Animals; D001516:Bees / Q000821:virology*; D020868:Gene Silencing; D010849:Picornaviridae / Q000187:drug effects* / Q000235:genetics / Q000502:physiology*; D012330:RNA, Double-Stranded / Q000494:pharmacology*; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D012330:RNA, Double-Stranded