title: Antihypertensive effects and endothelial progenitor cell activation by intake of chicken collagen hydrolysate in pre- and mild-hypertension.
abstract: Chicken collagen hydrolysate was given to 15 mildly hypertensive subjects for 4 weeks. Blood pressure was significantly decreased by 11.8 mmHg (P<0.01). A reduction in plasma renin activity was observed in blood test after intake. A colony assay of endothelial progenitor cells in blood samples from non-smokers revealed an approximately 30% increase in the number of colonies.
authors.affiliation: R&D Center, Nippon Meat Packers, Inc., Tsukuba, Ibaraki, Japan. a.egusa@nipponham.co.jp
authors.forename: Ai
authors.initials: A
authors.lastname: Saiga-Egusa
authors.forename: Koji
authors.initials: K
authors.lastname: Iwai
authors.forename: Toru
authors.initials: T
authors.lastname: Hayakawa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Takahata
authors.forename: Fumiki
authors.initials: F
authors.lastname: Morimatsu
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D002645:Chickens; D003094:Collagen / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004727:Endothelium / Q000166:cytology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011492:Protein Hydrolysates / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D013234:Stem Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000959:Antihypertensive Agents; D011492:Protein Hydrolysates; D003094:Collagen