title: [Clinical research of intraoperative floppy iris syndrome during operation].
abstract: Intraoperative floppy iris syndrome (IFIS) has been recently identified as a new small pupil syndrome during phacoemulsification. This syndrome is characterized by three intraoperative features: a flaccid iris stroma that undulates and bellows in response to intraocular fluid currents; a propensity for the floppy iris stroma to prolapse toward the tip of phacoemulsification and side-port incisions despite proper wound construction; and progressive intraoperative pupil constriction despite standard preventive preoperative pharmacologic measures designed to prevent this. It is now mostly considered that IFIS is associated with the use of tamsolusin, a highly selective alpha-1A receptor antagonist for the treatment of benign prostatic hypertrophy. It is recommended that a careful history of the use of alpha-1 blocking agents be taken before cataract surgery to anticipate the occurrence of IFIS. A combination of strategies could decrease the complications of IFIS. These procedures include preoperative use of atropine, intracameral injection of dilute phenylephrine or epinephrine, the use of super-cohesive ophthalmic viscosurgical devices, lower phacoemulsification vacuum and aspiration settings and various iris hooks or pupil dilators.
authors.affiliation: Department of Ophthalmology, Anhui Province Hospital, Affiliated of Anhui Medical University, Hefei 230001, China. symsb@163.com
authors.forename: Bing
authors.initials: B
authors.lastname: Sun
authors.forename: Si-qin
authors.initials: SQ
authors.lastname: Sun
authors.forename: Yue-chun
authors.initials: YC
authors.lastname: Wen
authors.forename: Rong-feng
authors.initials: RF
authors.lastname: Liao
mesh_terms: D058668:Adrenergic alpha-1 Receptor Antagonists; D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects; D006801:Humans; D007431:Intraoperative Complications; D007499:Iris Diseases / Q000209:etiology*; D015877:Miosis / Q000209:etiology; D018918:Phacoemulsification / Q000009:adverse effects*
chemical_list: D058668:Adrenergic alpha-1 Receptor Antagonists; D000317:Adrenergic alpha-Antagonists