Biomedical nanotechnology using virus-based nanoparticles.
A great challenge in biomedicine is the ability to target therapeutics to specific locations in the body in order to increase therapeutic benefit and minimize adverse effects. Virus-based nanotechnology takes advantage of the natural circulatory and targeting properties of viruses, in order to design therapeutics and vaccines that specifically target tissues of interest in vivo. Cowpea mosaic virus (CPMV) and flock house virus (FHV) nanoparticle-based strategies hold great promise for the design of targeted therapeutics, as well as for structure-based vaccine approaches.
Destito
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Kirin Pharma USA, Inc., La Jolla, CA 92037, USA.
Schneemann
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Manchester
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D000818:Animals; D017798:Comovirus / Q000235:genetics / Q000648:ultrastructure; D006801:Humans; D008958:Models, Molecular; D050997:Nanomedicine / Q000639:trends; D053758:Nanoparticles; D036103:Nanotechnology / Q000639:trends; D030381:Nodaviridae / Q000235:genetics / Q000648:ultrastructure; D014780:Viruses / Q000235:genetics / Q000648:ultrastructure