title: [Mannose-binding lectin and mortality in patients with type 2 diabetes mellitus--secondary publication].
abstract: We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM
authors.affiliation: Immunendokrinologisk Forskningsenhed, Medicinsk Afdeling M, Arhus Sygehus. tkh@dadlnet.dk
authors.forename: Troels Krarup
authors.initials: TK
authors.lastname: Hansen
authors.forename: Mari-Anne
authors.initials: MA
authors.lastname: Gall
authors.forename: Lise
authors.initials: L
authors.lastname: Tarnow
authors.forename: Steffen
authors.initials: S
authors.lastname: Thiel
mesh_terms: D000419:Albuminuria / Q000209:etiology; D002097:C-Reactive Protein / Q000032:analysis; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D037601:Mannose-Binding Lectin / Q000097:blood*; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D037601:Mannose-Binding Lectin; D002097:C-Reactive Protein