Massive aneurysmal dilatation of a depopulated ureteric hemodialysis xenograft.
Use of depopulated bovine ureteric xenografts for hemodialysis vascular access has recently been described. Cellular components have been removed, giving a connective tissue matrix which can be neocellularized, retaining native biomechanics. A 24-year-old male with end-stage renal disease from focal segmental glomerulosclerosis presented with particularly difficult vascular access. A depopulated bovine ureteric xenograft was implanted from the left subclavian artery to innominate vein. It became massively aneurysmal, requiring emergency embolization. Biopsy of the graft stained positive for alpha-gal. We believe this is the first reported case of massive aneurysmal dilatation of a depopulated bovine ureteric xenograft.
Smith
Matthew P Welberry
MP
Department of Renal Medicine, The Leeds Teaching Hoispitals NHS Trust, UK. mattws1@googlemail.com
Spark
James Ian
JI
Patel
Jai V
JV
Border
David J
DJ
Oswal
Dilip
D
Lewington
Andrew J P
AJ
D000328:Adult; D000783:Aneurysm / Q000209:etiology*; D000818:Animals; D001166:Arteriovenous Shunt, Surgical / Q000379:methods*; D001705:Bioprosthesis / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D016121:Brachiocephalic Veins / Q000601:surgery; D002417:Cattle; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D013348:Subclavian Artery / Q000601:surgery; D014183:Transplantation, Heterologous; D014513:Ureter / Q000637:transplantation*