title: [Seminoma clinical stage I: still open questions? : NSR study--a nationwide study of patterns of care].
abstract: Regarding the spectrum of clinical features of testicular germ cell tumours, seminoma clinical stage I (CSI) represents the most frequent clinical situation. According to current guidelines, four strategies are feasible for managing this stage: surveillance, para-aortal radiotherapy with 20 Gy, two courses of carboplatin (400 mg/m2 or AUC7), or a single course of carboplatin AUC7. Internationally published trials have revealed relapse rates of 15-20% with surveillance and 1.5-5% with adjuvant strategies. Basically, all relapses are curable. The German National Seminoma Registry study (NSR study) aims to analyse the patterns of care at the national level regarding use of the four management strategies for seminoma CSI. In addition, factors associated with therapeutic decision making will be evaluated. The second aim of the study is to find out whether the excellent results regarding relapse rates and overall survival in seminoma CSI as reported internationally can be reproduced.All urologic surgeons caring for seminoma patients in Germany are strongly encouraged to enter their patients into this national study of patterns of care.
authors.affiliation: Klinik für Urologie, Albertinen-Krankenhaus, Suentelstrasse 11a, 22457, Hamburg, Deutschland. DieckmannKP@t-online.de
authors.forename: K-P
authors.initials: KP
authors.lastname: Dieckmann
mesh_terms: D005858:Germany / Q000453:epidemiology; D006801:Humans; D033181:Information Dissemination / Q000379:methods*; D008297:Male; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D012042:Registries; D018239:Seminoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*