Characteristic prefrontal blood volume patterns when imaging body type, high-calorie food, and mother-child attachment in childhood anorexia nervosa: A near infrared spectroscopy study.
The aim of this study was to investigate the prefrontal activation in childhood anorexia nervosa (AN) patients when imaging symptom-provocative factors such as body type, high-calorie food, and attachment between mother and child. The prefrontal activations during each task, in terms of blood volume changes, were measured by near infrared spectroscopy. Twelve females with childhood AN (mean age, 14.4 years old) and 13 age-matched healthy female controls (mean age, 14.3 years old) participated in this study. Both groups showed increased prefrontal blood volume when viewing images of each symptom-provocative factor. Unexpectedly, there was no significant difference in the prefrontal blood volume increases between the control group and the childhood AN group when viewing images of slender and obese body types and high-calorie food. On the other hand, images of mother-child attachment resulted in significantly greater increases in prefrontal blood volume in the childhood AN group than in the control group. These results indicated that prefrontal activation in AN might be associated with imaging attachment between mother and child, but not associated with imaging body type or high-calorie food.
Nagamitsu
Shinichiro
S
Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan. kaoru@med.kurume-u.ac.jp
Yamashita
Fumiko
F
Araki
Yuko
Y
Iizuka
Chiho
C
Ozono
Shuichi
S
Komatsu
Hiroko
H
Ohya
Takashi
T
Yamashita
Yushiro
Y
Kakuma
Tatsuyuki
T
Tsuda
Akira
A
Matsuishi
Toyojiro
T
D000293:Adolescent; D000856:Anorexia Nervosa / Q000503:physiopathology / Q000523:psychology; D001810:Blood Volume / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002648:Child; D005260:Female; D005502:Food; D006801:Humans; D009034:Mother-Child Relations; D009483:Neuropsychological Tests; D017397:Prefrontal Cortex / Q000033:anatomy & histology / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D013008:Somatotypes / Q000523:psychology*; D019265:Spectroscopy, Near-Infrared / Q000379:methods