title: Recreational use of cocaine eliminates inhibition of return.
abstract: Chronic and recreational use of cocaine has been shown to impair inhibitory output control (response inhibition) but whether input control is also affected is an open question. For the first time, this study compared the ability to perform a cued target-discrimination task that measured inhibition of return (IOR), a reflexive inhibitory mechanism that delays attention from returning to a previously attended location, in adult recreational users and in a cocaine-free-matched sample controlled for age, race, gender distribution, and level of intelligence. Results show that the recreational use of cocaine eliminates IOR, suggesting that input control is strongly impaired.
authors.affiliation: Institute for Psychological Research, Department of Psychology, Leiden University, Leiden, the Netherland. colzato@fsw.leidenuniv.nl
authors.forename: Lorenza S
authors.initials: LS
authors.lastname: Colzato
authors.forename: Bernhard
authors.initials: B
authors.lastname: Hommel
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016022:Case-Control Studies; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000523:psychology*; D003463:Cues; D004192:Discrimination, Psychological / Q000187:drug effects*; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects*; D007266:Inhibition, Psychological; D008297:Male; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000187:drug effects; D055815:Young Adult
chemical_list: D013287:Illicit Drugs; D003042:Cocaine