title: Approach to the patient with sepsis.
abstract: This article reviews the current understanding of sepsis, severe sepsis, and septic shock. The article details definitions and epidemiology pertinent to the sepsis syndrome. A brief discussion of mechanisms of disease is followed a description of organ-specific failures related to sepsis. A concise review of the latest treatment options for each organ dysfunction is provided.
authors.affiliation: Division of Allergy, Pulmonary & Critical Care, Vanderbilt University Medical Center, Nashville, TN 37232-2650, USA.
authors.forename: Jason B
authors.initials: JB
authors.lastname: Martin
authors.forename: Arthur P
authors.initials: AP
authors.lastname: Wheeler
mesh_terms: D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D006801:Humans; D012307:Risk Factors; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*