(79)Br NMR spectroscopy as a practical tool for kinetic analysis.
(79)Br NMR spectroscopy has been used to monitor a series of reactions in which the bromide ion is produced, including the Menschutkin reaction of pyridine with a range of substituted benzyl bromides and a Heck coupling process. In cases where the process could also be monitored using (1)H NMR spectroscopy, the kinetic analyses using heteronuclear magnetic resonance spectroscopy were shown to be completely consistent. Both the utility of the process in following reactions which may be difficult to analyse using other techniques and the practical limitations associated with solvent choice are discussed.
Chan
Si Jia
SJ
School of Chemistry, University of New South Wales, Sydney NSW 2052, Australia.
Howe
Andrew G
AG
Hook
James M
JM
Harper
Jason B
JB
D001593:Benzyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D001966:Bromine / Q000737:chemistry*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011725:Pyridines / Q000737:chemistry; D013997:Time Factors
D001593:Benzyl Compounds; D011725:Pyridines; C023666:pyridine; D001966:Bromine; C038682:benzyl bromide