title: The causal model of insight in schizophrenia based on the Positive and Negative Syndrome Scale factors and the structural equation modeling.
abstract: We used structural equation modeling to formulate a causal model of insight in schizophrenia patients that explains the inconsistent results of the studies on the relationship between insight and psychopathology. The Positive and Negative Syndrome Scale was used to assess 342 patients with acute stage schizophrenia and 5 factors were identified through factor analysis with which a causal model of insight was constructed. Our model, where positive, negative, and autistic preoccupation (cognitive) factors were the primary predictors of insight with the activation factor mediating between positive and autistic preoccupation factors and insight, was found to show a perfect fit by most goodness-of-fit indices and to be superior to other alternative models. Specifically, positive, negative, and autistic preoccupation factors each had some predictive power for insight and the activation factor played a partial mediating role for the positive factor and a moderating role for the autistic preoccupation factor.
authors.affiliation: Department of Natural Science, Seoul National University, Seoul, Korea.
authors.forename: Samuel S-H
authors.initials: SS
authors.lastname: Hwang
authors.forename: Jae Seung
authors.initials: JS
authors.lastname: Chang
authors.forename: Kyu Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Yong Min
authors.initials: YM
authors.lastname: Ahn
authors.forename: Yong Sik
authors.initials: YS
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis / Q000523:psychology*; D001321:Autistic Disorder / Q000175:diagnosis / Q000523:psychology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006801:Humans; D007600:Judgment; D008297:Male; D008960:Models, Psychological; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics / Q000706:statistics & numerical data; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology*; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012803:Sick Role; D055815:Young Adult