title: Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis.
abstract: BACKGROUND
  The aim of the present study was to evaluate the accuracy of routine clinical examination (per vaginam, PV) combined with transvaginal sonography (TVS) for presurgical, non-invasive diagnosis of endometriosis.
  
  
  METHODS
  Two-hundred women with symptoms suggestive of endometriosis were prospectively assessed by PV and TVS prior to laparoscopy and radical resection of disease and histological confirmation.
  
  
  RESULTS
  Prevalence of endometriosis on the right/left (r/l) ovary, r/l uterosacral ligament (USL), pouch of Douglas (POD), vagina, bladder, rectovaginal space (RVS) and rectum was 12%, 13%, 12%, 22%, 15%, 11%, 2%, 4% and 24%. Sensitivities, specificities, positive and negative predictive values and positive and negative likelihood ratios for combined use of TVS and PV resulted in 96/100%, 100/99%, 100/93%, 93/100% and -;0.04/87.0;- for the r/l ovarian endometriosis; 67/84%, 97/86%, 73/62%, 96/95% and 19.56;0.35/5.97;0.19 for the r/l USL disease; 87%, 98%, 90%, 98% and 49.11;0.14 for involvement of the POD; 82%, 99%, 95%, 98% and 145.64;0.18 for vaginal endometriosis; 88%, 99%, 78%, 99% and 84.0;0.13 for endometriosis of the RVS; 75%, 98%, 50%, 99% and 49.0;0.25 for bladder involvement and 96%, 98%, 94%, 99% and 48.56;0.04 for rectal endometriosis.
  
  
  CONCLUSIONS
  The combination of PV and TVS accurately predicts the presence of endometriosis affecting the ovaries, vagina, rectum, USL, RVS and POD in patients with suspected endometriosis. We suggest the routine combination of PV and TVS as an essential part of the standard primary assessment of pelvic pain patients with suspected endometriosis.
authors.affiliation: Department of Obstetrics and Gynaecology, Centre for Endometriosis, Villach General Hospital, Nikolaigasse 43, 9500 Villach, Austria. gernot_hudelist@yahoo.de
authors.forename: G
authors.initials: G
authors.lastname: Hudelist
authors.forename: K H
authors.initials: KH
authors.lastname: Oberwinkler
authors.forename: C F
authors.initials: CF
authors.lastname: Singer
authors.forename: F
authors.initials: F
authors.lastname: Tuttlies
authors.forename: G
authors.initials: G
authors.lastname: Rauter
authors.forename: O
authors.initials: O
authors.lastname: Ritter
authors.forename: J
authors.initials: J
authors.lastname: Keckstein
mesh_terms: D000293:Adolescent; D000328:Adult; D004715:Endometriosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D017699:Pelvic Pain / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D015995:Prevalence; D014463:Ultrasonography / Q000379:methods*