Identifying the perpetrator in medulloblastoma: Dorian Gray versus Benjamin Button.
Tumors contain a subpopulation of tumor-propagating cells (TPCs) that are critical for their growth. In this issue, Read, Wechsler-Reya, and colleagues show that in an animal model of medulloblastoma, TPCs express the surface marker CD15 and have properties distinct from neural stem cells.
Lowry
Natalia Abramova
NA
New York Neural Stem Cell Institute, Rensselaer, NY 12144, USA.
Temple
Sally
S
D000818:Animals; D000951:Antigens, Neoplasm / Q000378:metabolism; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D016256:Lewis X Antigen / Q000378:metabolism; D008527:Medulloblastoma / Q000473:pathology / Q000503:physiopathology; D051379:Mice; D014411:Neoplastic Stem Cells / Q000473:pathology / Q000502:physiology
D000951:Antigens, Neoplasm; D016256:Lewis X Antigen