title: 15 STR loci frequencies with mutation rates in the population from Rio Grande do Sul, Southern Brazil.
abstract: Allele frequencies for 15 short tandem repeats (STR) loci were obtained from a sample of 2038 individuals undergoing paternity testing. The population is from Rio Grande do Sul, Brazil. The loci are the most commonly used in forensic and paternity testing, being analysed by the AmpFlSTR Identifiler (Applied Biosystems) commercial kit. The most polymorphic locus was D2S1338. Mutation rates were ascertained from this population sample. All the loci analysed reached the Hardy-Weinberg equilibrium. The results of genetic distance are consistent with the European-derived origins of Rio Grande do Sul population.
authors.affiliation: Laboratório de Investigação de Paternidade, Centro de Desenvolvimento Científico e Tecnológico, Fundação Estadual de Produção e Pesquisa em Saúde, Av. Ipiranga, 5400, Bairro Jardim Botânico, CEP 90610-000 Porto Alegre, RS, Brazil.
authors.forename: Fernanda Goulart Lanes
authors.initials: FG
authors.lastname: Chula
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Rodenbusch
authors.forename: Simone
authors.initials: S
authors.lastname: Schumacher
authors.forename: Tarciana
authors.initials: T
authors.lastname: Grandi
authors.forename: Candice Tosi
authors.initials: CT
authors.lastname: Michelon
authors.forename: André Zoratto
authors.initials: AZ
authors.lastname: Gastaldo
authors.forename: Cíntia
authors.initials: C
authors.lastname: Costi
authors.forename: Bianca
authors.initials: B
authors.lastname: Carvalho
authors.forename: Cláudia Maria Dornelles
authors.initials: CM
authors.lastname: da Silva
mesh_terms: D000483:Alleles; D053523:Amelogenin / Q000235:genetics; D001938:Brazil; D016172:DNA Fingerprinting; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D005787:Gene Frequency; D005828:Genetics, Population; D005843:Geography; D006579:Heterozygote; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D009154:Mutation; D010334:Paternity; D011786:Quality Control
chemical_list: D053523:Amelogenin