title: Diagnosis and treatment of osteoporosis.
abstract: Osteoporosis affects approximately 8 million women and 2 million men in the United States. The associated fractures are a common and preventable cause of morbidity and mortality in up to 50 percent of older women. The U.S. Preventive Services Task Force recommends using dual energy x-ray absorptiometry to screen all women 65 years and older and women 60 to 64 years of age who have increased fracture risk. Some organizations recommend considering screening in all men 70 years and older. For persons with osteoporosis diagnosed by dual energy x-ray absorptiometry or previous fragility fracture, effective first-line treatment consists of fall prevention, adequate intake of calcium (at least 1,200 mg per day) and vitamin D (at least 700 to 800 IU per day), and treatment with a bisphosphonate. Raloxifene, calcitonin, teriparatide, or hormone therapy maybe considered for certain subsets of patients.
authors.affiliation: Carilion Clinic Family Medicine Residency Program, Roanoke, Virginia 24017, USA. msweet@carilion.com
authors.forename: Mary Gayle
authors.initials: MG
authors.lastname: Sweet
authors.forename: Jon M
authors.initials: JM
authors.lastname: Sweet
authors.forename: Michael P
authors.initials: MP
authors.lastname: Jeremiah
authors.forename: Sim S
authors.initials: SS
authors.lastname: Galazka
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000368:Aged; D000375:Aging; D050071:Bone Density Conservation Agents / Q000008:administration & dosage; D002118:Calcium / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D015914:Estrogen Replacement Therapy / Q000379:methods; D005260:Female; D050723:Fractures, Bone / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000458:organization & administration; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000517:prevention & control; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis / Q000188:drug therapy; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D016896:Treatment Outcome; D014807:Vitamin D / Q000008:administration & dosage
chemical_list: D050071:Bone Density Conservation Agents; D014807:Vitamin D; D002118:Calcium