New room temperature ionic liquids with interesting ecotoxicological and antimicrobial properties.
A new set of room temperature ionic liquids (RTIL), tetrabutylammonium (TBA) salts: formate, acetate, propionate, butyrate, benzoate, nitrobenzoate, cinnamate, salicylate, sulfanilate, linoleate, and oleate, were prepared by neutralization of tetrabutylammonium hydroxide (TBA OH) and the corresponding acid. The compounds showed interesting chemical and biological properties. They are soluble in water and organic solvents producing conducting solutions and are effective against certain Gram-negative as well as Gram-positive bacteria. Notably, they affected some proteins such as bovine serum albumin (BSA) and catalase (CAT) as inferred by following the fluorescence emission spectra.
Saadeh
Salman M
SM
Chemistry Department, The Islamic University, Gaza, Palestine. ssaadeh@iugaza.edu.ps
Yasseen
Zeyad
Z
Sharif
Fadel A
FA
Abu Shawish
Hazem M
HM
D000890:Anti-Infective Agents / Q000737:chemistry / Q000633:toxicity*; D002374:Catalase / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D052578:Ionic Liquids / Q000737:chemistry / Q000633:toxicity*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry / Q000633:toxicity*; D012710:Serum Albumin, Bovine / Q000187:drug effects; D013050:Spectrometry, Fluorescence; D013696:Temperature
D000890:Anti-Infective Agents; D052578:Ionic Liquids; D000644:Quaternary Ammonium Compounds; D012710:Serum Albumin, Bovine; C009405:tetrabutylammonium; D002374:Catalase