Enantioselective synthesis of tetrafluorinated ribose and fructose.
A perfluoroalkylidene lithium mediated cyclisation approach for the enantioselective synthesis of a tetrafluorinated aldose (ribose) and of a tetrafluorinated ketose (fructose), both in the furanose and in the pyranose form, is described.
Linclau
Bruno
B
School of Chemistry, University of Southampton, Highfield, Southampton, UK. bruno.linclau@soton.ac.uk
Boydell
A James
AJ
Timofte
Roxana S
RS
Brown
Kylie J
KJ
Vinader
Victoria
V
Weymouth-Wilson
Alexander C
AC
D003500:Cyclization; D005461:Fluorine; D005632:Fructose / Q000031:analogs & derivatives / Q000138:chemical synthesis; D012266:Ribose / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D013237:Stereoisomerism
D005461:Fluorine; D005632:Fructose; D012266:Ribose