title: Genetic and non-genetic determinants of outcomes in cystic fibrosis.
abstract: The treatment of cystic fibrosis has improved significantly over the past three decades. Median survival has improved by decades and is now estimated to be 37 years. Many factors contribute to improvements in disease severity and outcome. This paper reviews the current evidence of three groups of important factors: genetic, environmental and healthcare related.
authors.affiliation: Emory Cystic Fibrosis Center, Emory University, Atlanta, Georgia, USA. Lindy.Wolfenden@emoryhealthcare.org
authors.forename: Linda L
authors.initials: LL
authors.lastname: Wolfenden
authors.forename: Michael S
authors.initials: MS
authors.lastname: Schechter
mesh_terms: D003550:Cystic Fibrosis / Q000235:genetics* / Q000628:therapy*; D004781:Environmental Exposure; D006801:Humans; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D014028:Tobacco Smoke Pollution