title: Fanconi anemia complicated by neutropenic enterocolitis.
abstract: BACKGROUND
  Neutropenic enterocolitis (NEC) also known as typhlitis is an acute, life-threatening inflammation of the small and large bowel often seen in patients with leukaemia undergoing cytotoxic chemotherapy: occasionally this syndrome could present in other immunocompromised patients.
  
  
  OBJECTIVE
  To report an unusual case of Fanconi anemia complicated by neutropenic enterocolitis.
  
  
  METHODS
  We report a case of a 13-year-old boy affected by Fanconi anemia with severe neutropenia and who presented neutropenic enterocolitis. Abdominal ultrasonography showed thickening of cecum and ascending colon of 1.18cm. The outcome was favourable with medical management.
  
  
  CONCLUSIONS
  Neutropenic enterocolitis in Fanconi anemia is a rare and a severe illness: however, the outcome is improved with early management.
authors.affiliation: Department of Pediatrics B, Children's Hospital of Tunis, Tunis, Tunisia.
authors.forename: Faten
authors.initials: F
authors.lastname: Tinsa
authors.forename: Nesrine
authors.initials: N
authors.lastname: Necib
authors.forename: Manef
authors.initials: M
authors.lastname: Guesmi
authors.forename: Olfa
authors.initials: O
authors.lastname: Bousnina
authors.forename: Wiem
authors.initials: W
authors.lastname: Douira
authors.forename: Khadija
authors.initials: K
authors.lastname: Bousetta
authors.forename: Souad
authors.initials: S
authors.lastname: Bousnina
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001803:Blood Transfusion; D002442:Ceftazidime / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D044504:Enterocolitis, Neutropenic / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005199:Fanconi Anemia / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005839:Gentamicins; D008795:Metronidazole; D002442:Ceftazidime