title: [Influence of long-term contact lens wear on the cornea according to the data confocal microscopy].
abstract: The paper presents the results of a comparative study of corneal morphological changes by lifetime confocal miscroscopy in the long-term use of various types of contact lenses (CLs). Twenty-two patients (44 eyes) were examined, of them 8 patients (16 eyes) had worn soft CLs (SCLs) for 10-25 years (mean 17 years). 8 (16 eyes) had used hard CLs (HCLs) made of polymethyl metacrylate for 17-30 years (mean 23 years), 6 (12 eyes) had worn HCLs for 15 to 30 years (mean 20 years), hard gas-permeable CLs (HGCLs) over the past 5-15 years. The findings suggest that long-term wear of corrective CLs may lead to significant structural impairments in different corneal layers. The most characteristic changes are different types of epitheliopathies and the emergence of the signs of stromal degeneration with formation of deposits. According to our evidence, the likelihood of the detected changes increases with the long use of SCLs and reduces with the wear of HCLs, HGCLs in particular, which allows the authors to recommend that SCLs be changed to HGCLs after long (more than 10-15-year) contact correction.
authors.forename: G B
authors.initials: GB
authors.lastname: Egorova
authors.forename: A A
authors.initials: AA
authors.lastname: Fedorov
authors.forename: N V
authors.initials: NV
authors.lastname: Bobrovskikh
mesh_terms: D003261:Contact Lenses / Q000009:adverse effects*; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects*; D003316:Corneal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D003319:Corneal Stroma / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D018613:Microscopy, Confocal; D019904:Polymethyl Methacrylate; D013997:Time Factors
chemical_list: D019904:Polymethyl Methacrylate