Acute inflammatory encephalomyelitis following Campylobacter enteritis associated with high titre antiganglioside GM1 IgG antibodies.
Campylobacter enteritis is commonly associated with various forms of the Guillain-Barré syndrome but not central nervous system (CNS) inflammation. We present a case of Campylobacter enteritis associated with acute inflammatory encephalomyelitis and high titre antiganglioside GM1 IgG antibodies. The finding of antiganglioside antibodies in inflammatory demyelination of the CNS may identify avenues for research into pathogenesis. The relationship between antiganglioside antibodies and CNS inflammation is discussed.
Young
John W
JW
Department of Neurology, Christchurch Public Hospital, Christchurch, New Zealand. wljyoung@hotmail.com
Mason
Deborah F
DF
Taylor
Bruce V
BV
D000208:Acute Disease; D002169:Campylobacter Infections / Q000150:complications / Q000276:immunology* / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D004679:Encephalomyelitis / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D005260:Female; D005677:G(M1) Ganglioside / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008279:Magnetic Resonance Imaging / Q000379:methods; D013116:Spinal Cord / Q000473:pathology; D055815:Young Adult
D007074:Immunoglobulin G; D005677:G(M1) Ganglioside