Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a verongid sponge.
Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.
Mukai
Hiroya
H
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Kubota
Takaaki
T
Aoyama
Kazuki
K
Mikami
Yuzuru
Y
Fromont
Jane
J
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D007093:Imidazoles / Q000302:isolation & purification* / Q000494:pharmacology; D011161:Porifera; D015363:Quinolones / Q000302:isolation & purification* / Q000494:pharmacology; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007093:Imidazoles; D015363:Quinolones; C475724:bromotyrosine; D014443:Tyrosine