Dyke-Davidoff-Masson syndrome in postcerebral malaria.
Dyke-Davidoff-Masson syndrome is a disorder involving hemiatrophy or hypoplasia of 1 cerebral hemisphere secondary to an insult in the developing brain. Often this will manifest with seizures, hemiparesis, mental retardation, and facial changes. Associated with this pathology are the radiologically evident changes, such as thickening of the calvarium, hyperpneumatization of the sinuses, and dilation of the ipsilateral lateral ventricle among others. The following is a case presentation of an 18-year-old female emigrating from Ghana who presented to the emergency department with complaints of seizures diagnosed as being caused by cerebral malaria at 13 years of age. We hypothesize that the cerebral malaria and related vascular occlusion are the causes of her acquired cerebral changes. Included are computed tomography images.
Karuppiah
Sabesan
S
Bronx Lebanon Family Medicine Residency Program, 100 Hospital Plaza Apt 608, Paterson, New Jersey 07503, USA. sabesan@yahoo.com
Rodgman
Christopher
C
Lombard
Jay
J
D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001284:Atrophy / Q000469:parasitology* / Q000473:pathology / Q000503:physiopathology; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000469:parasitology* / Q000473:pathology; D004827:Epilepsy / Q000469:parasitology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005626:Frontal Sinus / Q000000981:diagnostic imaging / Q000473:pathology; D005632:Fructose / Q000031:analogs & derivatives / Q000627:therapeutic use; D005869:Ghana; D006801:Humans; D015576:Hyperostosis / Q000000981:diagnostic imaging / Q000469:parasitology / Q000473:pathology; D020547:Lateral Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D016779:Malaria, Cerebral / Q000150:complications*; D012886:Skull / Q000000981:diagnostic imaging / Q000473:pathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D000077236:Topiramate; D016896:Treatment Outcome
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose