title: [Practice, problems and perspectives of opioid substitution treatment (OST) in Germany].
abstract: Opioid dependency is a complex and chronically relapsing disease with high risks of morbidity and mortality. Frequent relapses and in most of the cases a long process of maturing out characterize this disease. Opioid substitution programs with methadone, buprenorphine and other opioids are a suitable intervention and form the first choice in the treatment of this disease. In Germany, compared to its neighboring countries, this treatment was introduced relatively late. However, in the last five years, the number of patients in substitution treatment has increased significantly to more than 70,000 patients, which marks an increase of 50%, meaning that one third to one half of the estimated opiate users are being reached. Despite the widely acknowledged success with respect to the improvement of the quality of life, survival rates, and accessibility of the target groups for ongoing treatments of drug-related diseases (such as HIV/HCV infections), opioid substitution treatment is still discussed controversially. In this contribution, problems in the areas of service provision, juristic, social, health and research policies are discussed and possibilities of increasing the access and quality of this treatment are introduced.
authors.affiliation: Bundesministerium für Gesundheit, Berlin, BRD.
authors.forename: I I
authors.initials: II
authors.lastname: Michels
authors.forename: G
authors.initials: G
authors.lastname: Sander
authors.forename: H
authors.initials: H
authors.lastname: Stöver
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use*; D005858:Germany / Q000453:epidemiology; D015658:HIV Infections / Q000401:mortality* / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D009293:Opioid-Related Disorders / Q000209:etiology / Q000401:mortality* / Q000534:rehabilitation*; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid