Neutral desorption using a sealed enclosure to sample explosives on human skin for rapid detection by EESI-MS.
A novel air-tight neutral desorption enclosure has been fabricated to noninvasively sample low picograms of explosives 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetraazocine (HMX), triacetone triperoxide (TATP), and nitroglycerin (NG) from human skin using a neutral nitrogen gas beam. Without further sample pretreatment, the explosive mixtures collected from the skin surface were directly transported by a nitrogen carrier gas over a 4-m distance for sensitive detection and rapid identification by extractive electrospray ionization tandem mass spectrometry.
Chen
Huanwen
H
College of Chemistry, Biology, and Material Science, East China Institute of Technology, Fuzhou, PR China. chw8868@gmail.com
Hu
Bin
B
Hu
Yan
Y
Huan
Yanfu
Y
Zhou
Zhiquan
Z
Qiao
Xiaolin
X
D053834:Explosive Agents / Q000032:analysis*; D009584:Nitrogen / Q000737:chemistry; D012680:Sensitivity and Specificity; D012867:Skin / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D053719:Tandem Mass Spectrometry
D053834:Explosive Agents; D009584:Nitrogen