title: Laparoscopic radical cholecystectomy.
abstract: Controversy exists as to the role of minimally invasive techniques in the management of early gallbladder cancer. The majority of early gallbladder cancers are diagnosed upon final pathology after laparoscopic cholecystectomy. For stage pT1a tumors, no further surgery is warranted; however, for pT1b or greater lesions, patients usually undergo port-site excisions and completion of open radical cholecystectomy involving a partial hepatectomy of segments IV and V and a lymphadenectomy of the hepatoduodenal ligament. Presented in this paper is a totally laparoscopic radical cholecystectomy performed for suspected early gallbladder cancer. Despite the fact that a preoperative serum IgG4 level was within normal limits, final pathology was consistent with autoimmune cholecystitis. As a result, the laparoscopic radical cholecystectomy may be useful in select patients with a preoperative suspicion of early-stage gallbladder cancer by sparing them the necessity of a second-stage open procedure.
authors.affiliation: Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. Andrew.Gumbs@fccc.edu
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Gumbs
authors.forename: Luca
authors.initials: L
authors.lastname: Milone
authors.forename: Rula
authors.initials: R
authors.lastname: Geha
authors.forename: Johanna
authors.initials: J
authors.lastname: Delacroix
authors.forename: John A
authors.initials: JA
authors.lastname: Chabot
mesh_terms: D000368:Aged; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D002764:Cholecystitis / Q000097:blood / Q000473:pathology / Q000601:surgery*; D005706:Gallbladder Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male
chemical_list: D007074:Immunoglobulin G