title: Bayesian QTL mapping for multiple families derived from crossing a set of inbred lines to a reference line.
abstract: In some crop species, germplasm collections consisting of a large number of accessions that include traditional landraces, modern cultivars and wild species have recently been established. Such collections are regarded as useful stocks of genes for breeding programs. However, to efficiently utilize these collections for plant breeding, understanding genetic variation in agronomic traits at the QTL level between the accessions is indispensable. One effective way to extract the actual QTL information included in these collections is to perform QTL analysis jointly for multiple families derived from crossing some accessions of the collection with a single reference line such as a standard commercial variety. We developed a Bayesian method for jointly analyzing QTL in such interconnected multiple families derived from a set of inbred lines crossed to the reference line, to detect QTL segregating between any of the inbred lines and the reference line. In this study, we considered multiple recombinant inbred lines, each of which was derived from crossing each of the inbred lines to the reference line. The method was evaluated through the use of simulated data sets for its efficiency in detecting QTL and identifying families segregating at each QTL.
authors.affiliation: Division of Animal Sciences, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan. hayatk@affrc.go.jp
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Iwata
mesh_terms: D001499:Bayes Theorem; D007178:Inbreeding; D008957:Models, Genetic; D015233:Models, Statistical; D010944:Plants / Q000235:genetics*; D040641:Quantitative Trait Loci