Mebendazole in parasitic infections other than those caused by soil-transmitted helminths.
Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence that this drug, taken at higher doses than used for STH and enterobiasis, could be sufficiently effective on some protozoa, nematodes and cestodes.
Cañete
R
R
Center for Hygiene, Epidemiology and Microbiology, Matanzas City, Cuba.
Escobedo
A A
AA
Almirall
P
P
González
M E
ME
Brito
K
K
Cimerman
S
S
D000293:Adolescent; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005873:Giardiasis / Q000188:drug therapy*; D006373:Helminthiasis / Q000188:drug therapy*; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D008463:Mebendazole / Q000191:economics / Q000627:therapeutic use*; D016896:Treatment Outcome; D014247:Trichomonas Vaginitis / Q000188:drug therapy*
D000977:Antiparasitic Agents; D008463:Mebendazole