Coronary artery restenosis: a paradigm of current treatment approaches.
Percutaneous coronary artery revascularization has now evolved to a status where angioplasty and stenting have become routine practice for the treatment of significant obstructive atherosclerotic vascular disease. Angioplasty and stenting have become routine practice for the treatment of significant obstructive atherosclerotic vascular disease. Neointimal formation is the pathological basis for restenosis after coronary angioplasty and stenting. The authors discuss the current methods to treat and prevent coronary artery restenosis.
Kiernan
T J
TJ
Section of Vascular Medicine and Cardiology Intervention, Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. tjkiernan@partners.org
Kiernan
G D
GD
Yan
B D
BD
D015906:Angioplasty, Balloon, Coronary; D050197:Atherosclerosis / Q000628:therapy; D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000209:etiology / Q000628:therapy*; D023903:Coronary Restenosis / Q000209:etiology / Q000517:prevention & control*; D054855:Drug-Eluting Stents; D042783:Endothelial Cells / Q000637:transplantation; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome