title: Periodontal status in subjects with hyperlipidemia.
abstract: BACKGROUND
  Hyperlipidemia is a major risk factor for cardiovascular disease. Recent reports showed a possible association between periodontal disease and an increased risk for cardiovascular disease. The aim of this study was to evaluate whether hyperlipidemia has any influence on periodontal status.
  
  
  METHODS
  Fifty-one subjects with hyperlipidemia and 47 normolipidemic subjects participated in this study. Biochemical parameters, including plasma triglyceride, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels, and periodontal parameters, including plaque index (PI), probing depth (PD), clinical attachment level (CAL), and percentage of sites with bleeding on probing (BOP [%]), were evaluated.
  
  
  RESULTS
  The mean values of PI, PD, CAL, and BOP (%) for the hyperlipidemic group were significantly higher than those for the control group. Plasma triglyceride, total cholesterol, and LDL-C levels were significantly and positively associated with PI, PD, BOP (%), and CAL. HDL-C was significantly, but negatively, associated with CAL. Plasma triglyceride level was significantly associated with PD and BOP (%) after further analyses.
  
  
  CONCLUSIONS
  The results of our study showed that patients with mild or moderate hyperlipidemia manifested higher values of periodontal parameters compared to normolipidemic individuals. Further studies are needed to determine the effect of hyperlipidemia on periodontal disease.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Süleyman Demirel University, Isparta, Turkey. ofentoglu@yahoo.com
authors.forename: Ozlem
authors.initials: O
authors.lastname: Fentoğlu
authors.forename: Gül
authors.initials: G
authors.lastname: Oz
authors.forename: Pelin
authors.initials: P
authors.lastname: Taşdelen
authors.forename: Ersin
authors.initials: E
authors.lastname: Uskun
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Aykaç
authors.forename: F Yeşim
authors.initials: FY
authors.lastname: Bozkurt
mesh_terms: D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000097:blood / Q000209:etiology*; D010512:Periodontal Index; D012044:Regression Analysis; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D002784:Cholesterol