title: [Diffuse interstitial lung disease related to peribronchiolar metaplasia].
abstract: Peribronchiolar metaplasia is a histologic lesion characterized by fibrosis and bronchiolar epithelial proliferation, affecting peribronchiolar alveolar septa and terminal bronchioles. It has been considered a nonspecific tissue reaction secondary to the action of external factors, such as tobacco smoke and microbes, and is a common histologic finding in several diffuse interstitial lung diseases. Several such cases with clinical, radiologic, and lung function manifestations characteristic of idiopathic interstitial pneumonia have been described recently, all having peribronchiolar metaplasia as the only histologic abnormality. We report 2 cases of interstitial lung disease in which peribronchiolar metaplasia was the only finding of pathology.
authors.affiliation: Servicio de Neumología, Hospital Clínic, Universitat de Barcelona, Barcelona, España. estebanmallorca@gmail.com
authors.forename: Esteban
authors.initials: E
authors.lastname: Cano-Jiménez
authors.forename: María
authors.initials: M
authors.lastname: Molina-Molina
authors.forename: José
authors.initials: J
authors.lastname: Ramírez
authors.forename: Marcelo
authors.initials: M
authors.lastname: Sánchez
authors.forename: Joan Lluis
authors.initials: JL
authors.lastname: Aliaga
authors.forename: Antoni
authors.initials: A
authors.lastname: Xaubet
mesh_terms: D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000209:etiology*; D008297:Male; D008679:Metaplasia / Q000150:complications; D008875:Middle Aged