First-in-man and first-of-class-in-man clinical trials in oncology.
Mross
K
K
Albert Ludwigs University, Freiburg, Germany. mross@tumorbio.uni-freiburg.de
D054316:Biomarkers, Pharmacological; D017321:Clinical Trials, Phase I as Topic; D017322:Clinical Trials, Phase II as Topic; D054697:Cytostatic Agents / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D003603:Cytotoxins / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004333:Drug Administration Routes; D006801:Humans; D020714:Maximum Tolerated Dose; D008495:Medical Oncology / Q000379:methods* / Q000592:standards; D018579:Patient Selection
D054316:Biomarkers, Pharmacological; D054697:Cytostatic Agents; D003603:Cytotoxins