Autoimmune angioneurotic edema in a patient with Helicobacter pylori infection.
Association of acquired autoimmune angioneurotic edema with other diseases is increasing. However, the precise mechanism by which antibodies to C1-esterase inhibitor (C1-INH) are produced, is not elucidated. We describe a patient with IgA antibodies against C1-INH without other autoimmune markers. Our patient had gastritis and Helicobacter pylori infection, proven by biopsy. This case suggests that H. pylori infection can act as triggering factor for acquired autoimmune angioneurotic edema.
Mukeba
Didier
D
Department of Internal Medicine and Infectious Diseases, Centre Hospitalier Universitaire, Liege, Belgium.
Chandrikakumari
Kavitha
K
Giot
Jean-Baptiste
JB
Leonard
Philippe
P
Meuris
Christelle
C
Frippiat
Frederic
F
Moutschen
Michel
M
D000799:Angioedema / Q000209:etiology* / Q000276:immunology*; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D050718:Complement C1 Inhibitor Protein / Q000276:immunology; D005756:Gastritis / Q000150:complications / Q000382:microbiology; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D008875:Middle Aged
D050718:Complement C1 Inhibitor Protein; D007070:Immunoglobulin A