title: Indications for upper gastrointestinal endoscopy. The accuracy of the American Society for Gastrointestinal Endoscopy guidelines in a Portuguese hospital.
abstract: BACKGROUND
  The appropriateness of the indications for upper gastro-intestinal endoscopy (EGD) is crucial in assessing quality in endoscopy units, improving cost-effectiveness and providing better patient care. Using the American Society for Gastrointestinal Endoscopy (ASGE) guidelines, the aim of this study was to evaluate the appropriate use of EGD and to measure the local accuracy of these guidelines.
  
  
  METHODS
  Over a two year period information was gathered on 2305 consecutive patients--1146 (50% males)--of whom had an EGD performed at our unit. Patients were referred for EGD by other physicians of the hospital staff or through the gastroenterology out-patient clinic. The appropriateness, sensitivity, specificity and predictive value of the ASGE guidelines were established using EGD diagnosis as gold standard. Atrophic gastritis and hiatus hernia were considered irrelevant diagnosis.
  
  
  RESULTS
  According to the ASGE guidelines the rate of inappropriateness was 20%. No lesions or irrelevant lesions were found in 30.6% EGD. Appropriately indicated endoscopies disclosed significantly more clinically relevant findings (71.3%) than endoscopies performed with indications that were not ASGE listed (61.7%) - p < 0.01, OR = 1.55, 95% CI (1.24-1.92) but no significant difference was found between appropriateness and inappropriateness in patients with a diagnosis of gastric cancer: p = 0.21, OR = 1.53, 95% CI (0.75-3.21). The sensitivity of the ASGE criteria was 82.1%, the specificity 25.2%, the positive predictive value 71% and the negative predictive value 38.1%. Gastric cancer was found in 10 (0.4%) of the patients not appropriately indicated.
  
  
  CONCLUSIONS
  In this Portuguese population sample, the accuracy of the ASGE guidelines is too low to be confidently acceptable. This suggests that, in Portugal, a country with a high prevalence of gastric cancer, wider criteria must be applied, if useful local guidelines for appropriate referrals are expected.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, S. Sebastião Hospital, Santa Maria da Feira.
authors.forename: Rute
authors.initials: R
authors.lastname: Cerqueira
authors.forename: Carolina
authors.initials: C
authors.lastname: Fernandes
authors.forename: Manuel
authors.initials: M
authors.lastname: Correia
authors.forename: M Conceição
authors.initials: MC
authors.lastname: Manso
mesh_terms: D000328:Adult; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D011174:Portugal; D017410:Practice Guidelines as Topic / Q000592:standards*; D015203:Reproducibility of Results