Human papillomavirus-associated squamous cell carcinoma of the nail bed in African-American patients.
BACKGROUND
Human papillomavirus (HPV) has been implicated in the development of digital squamous cell carcinoma (SCC). Case reports in the literature mostly identify HPV type 16 present in tumors, but HPV types 2, 31, 34, 35, and 73 have also been isolated.


METHODS
Two cases of digital SCC associated with HPV 16 in young African-American men are presented.


CONCLUSIONS
Digital SCC associated with HPV may be difficult to evaluate and treat, particularly in African-Americans and patients with human immunodeficiency virus (HIV). We discuss the need for careful evaluation, treatment, and follow-up of these individuals.
Turowski
Cheryl Bansal
CB
Department of Dermatology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19107, USA.
Ross
Amy S
AS
Cusack
Carrie Ann
CA
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000328:Adult; D001741:Black or African American; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery / Q000821:virology*; D052162:Human papillomavirus 16; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000473:pathology / Q000601:surgery / Q000821:virology*; D030361:Papillomavirus Infections / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery / Q000821:virology*