Oxidative stress and myeloperoxidase levels in saliva of patients with recurrent aphthous stomatitis.
OBJECTIVE
Recurrent aphthous stomatitis (RAS) is the most common oral ulcerative condition affecting 5-25% of the general population. The aim of this study was to evaluate the oxidative stress parameters in saliva of patients with RAS and to investigate the relationship among these parameters in either group.


METHODS
The study involved 50 patients with RAS of whom 24 were male and 26 were female, and 25 healthy controls of whom 13 were male and 12 were female.


RESULTS
There was no statistically significant difference in the salivary total antioxidant capacity, total oxidant status, oxidative stress index levels, and myeloperoxidase activity between patients with RAS and those in the control group.


CONCLUSIONS
The results show that reactive oxygen species may not play a role in the etiology of RAS.
Cağlayan
F
F
Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey. facagla@atauni.edu.tr
Miloglu
O
O
Altun
O
O
Erel
O
O
Yilmaz
A B
AB
D000328:Adult; D000975:Antioxidants / Q000032:analysis; D004396:Coloring Agents; D005260:Female; D006801:Humans; D017665:Hydroxyl Radical; D008297:Male; D016877:Oxidants / Q000032:analysis; D018384:Oxidative Stress / Q000502:physiology*; D009195:Peroxidase / Q000032:analysis*; D012008:Recurrence; D012463:Saliva / Q000737:chemistry* / Q000201:enzymology; D013053:Spectrophotometry; D013281:Stomatitis, Aphthous / Q000201:enzymology / Q000378:metabolism*; D055815:Young Adult
D000975:Antioxidants; D004396:Coloring Agents; D016877:Oxidants; D017665:Hydroxyl Radical; D009195:Peroxidase