title: Comparison of partial coherence interferometry and ultrasound for anterior segment biometry.
abstract: OBJECTIVE
  To assess the performance of a partial coherence interferometry (PCI)-based device for the determination of anterior segment biometry.
  
  
  METHODS
  Clinica Centrofama, Cartagena, Murcia, Spain.
  
  
  METHODS
  Central corneal thickness (CCT), anterior chamber depth (ACD), and lens thickness (LT) were measured with the ACMaster PCI anterior segment biometer and an Echoscan US-1800 ultrasound (US) biometer/pachymeter with and without cycloplegia. To determine the precision of the instruments, the same examiner took 30 consecutive CCT, ACD, and LT measurements in a single subject under the same conditions and with and without cycloplegia. The same measurements were performed in additional subjects.
  
  
  RESULTS
  Twenty-one eyes (16 subjects) were evaluated. Repeated measurements of the single subject yielded a standard deviation of 4.0 microm for CCT, 106.0 microm for ACD, and 323.0 microm for LT; there were many peaks, mainly in the last 10 readings. There was a high correlation between CCT measurements with both systems with and without cycloplegia (r(2)>0.93), with the US system giving higher values. Differences were significant (P< .001), but not consistent, throughout the range of corneal thicknesses and were greater for thicker corneas. Differences in ACD and LT measurements were similar. Agreement between systems in ACD and LT measurements was considerably lower than for CCT measurements.
  
  
  CONCLUSIONS
  The PCI biometer provided precise CCT measurements. The ACD and LT measurements had a higher variance. Differences in CCT measurements between the 2 systems were greater for thicker corneas, with higher values with the US system.
authors.affiliation: Vision Sciences Research Group, Instituto Universitario de Investigación en Envejecimiento, University of Murcia, Murcia, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Lara
authors.forename: Vicente
authors.initials: V
authors.lastname: Fernández-Sánchez
authors.forename: Norberto
authors.initials: N
authors.lastname: López-Gil
authors.forename: Alejandro
authors.initials: A
authors.lastname: Cerviño
authors.forename: Robert
authors.initials: R
authors.lastname: Montés-Micó
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000033:anatomy & histology*; D001699:Biometry / Q000295:instrumentation*; D001837:Body Weights and Measures; D003315:Cornea / Q000033:anatomy & histology*; D003941:Diagnostic Techniques, Ophthalmological; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D006801:Humans; D007368:Interferometry; D007908:Lens, Crystalline / Q000033:anatomy & histology*; D008027:Light; D008297:Male; D009184:Mydriatics / Q000008:administration & dosage; D011680:Pupil / Q000187:drug effects; D015203:Reproducibility of Results; D013016:Sound
chemical_list: D009184:Mydriatics