title: Sedation and analgesia for the mechanically ventilated patient.
abstract: Mechanically ventilated patients in the intensive care unit routinely require sedative and analgesic medications to manage pain and anxiety. These medications may have unpredictable effects with long-term use. Strategies that may help to improve patient outcomes include thoughtful selection of medications, use of objective sedation and pain scales, and implementation of protocolized sedation.
authors.affiliation: Department of Medicine, University of Chicago Medical Center, Chicago, IL 60637, USA.
authors.forename: David R
authors.initials: DR
authors.lastname: Brush
authors.forename: John P
authors.initials: JP
authors.lastname: Kress
mesh_terms: D000698:Analgesia / Q000379:methods*; D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D016292:Procedural Sedation / Q000379:methods*; D003422:Critical Care / Q000379:methods*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects / Q000627:therapeutic use*; D007362:Intensive Care Units; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D012121:Respiration, Artificial
chemical_list: D000700:Analgesics; D006993:Hypnotics and Sedatives