title: Inhalation and ingestion intakes with associated dose estimates for level II and level III personnel using Capstone study data.
abstract: Depleted uranium (DU) intake rates and subsequent dose rates were estimated for personnel entering armored combat vehicles perforated with DU penetrators (level II and level III personnel) using data generated during the Capstone DU Aerosol Study. Inhalation intake rates and associated dose rates were estimated from cascade impactors worn by sample recovery personnel and from cascade impactors that served as area monitors. Ingestion intake rates and associated dose rates were estimated from cotton gloves worn by sample recovery personnel and from wipe-tests samples from the interior of vehicles perforated with large-caliber DU munitions. The mean DU inhalation intake rate for level II personnel ranged from 0.447 mg h(-1) based on breathing zone monitor data (in and around a perforated vehicle) to 14.5 mg h(-1) based on area monitor data (in a perforated vehicle). The mean DU ingestion intake rate for level II ranged from 4.8 mg h(-1) to 38.9 mg h(-1) based on the wipe-tests data including surface-to-glove transfer factors derived from the Capstone data. Based on glove contamination data, the mean DU ingestion intake rates for level II and level III personnel were 10.6 mg h(-1) and 1.78 mg h(-1), respectively. Effective dose rates and peak kidney uranium concentration rates were calculated based on the intake rates. The peak kidney uranium concentration rate cannot be multiplied by the total exposure duration when multiple intakes occur because uranium will clear from the kidney between the exposures.
authors.affiliation: U.S. Army Center for Health Promotion and Preventive Medicine, 5158 Blackhawk Road, Aberdeen Proving Ground, MD 21010-5403, USA. fran.szrom@us.army.mil
authors.forename: Frances
authors.initials: F
authors.lastname: Szrom
authors.forename: Gerald A
authors.initials: GA
authors.lastname: Falo
authors.forename: Gordon M
authors.initials: GM
authors.lastname: Lodde
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Parkhurst
authors.forename: Eric G
authors.initials: EG
authors.lastname: Daxon
mesh_terms: D000280:Administration, Inhalation; D000284:Administration, Oral; D000336:Aerosols / Q000032:analysis / Q000493:pharmacokinetics*; D000398:Air Pollution, Radioactive / Q000706:statistics & numerical data*; D000465:Algorithms; D001610:Beta Particles; D001822:Body Burden; D003198:Computer Simulation; D005389:Firearms / Q000706:statistics & numerical data*; D047830:Gulf War; D006801:Humans; D015994:Incidence; D008889:Military Personnel; D016273:Occupational Exposure / Q000706:statistics & numerical data*; D009928:Organ Specificity; D011834:Radiation Monitoring / Q000379:methods; D011850:Radioactive Waste / Q000706:statistics & numerical data; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D014018:Tissue Distribution; D014481:United States / Q000453:epidemiology; D014501:Uranium / Q000032:analysis / Q000493:pharmacokinetics*
chemical_list: D000336:Aerosols; D011850:Radioactive Waste; D014501:Uranium