Chloroquine -induced hair depigmentation.
A case of hair depigmentation induced by chloroquine diphosphate subacute overdosage in an 11-year-old patient with dermatomyositis is presented. Normal coloured hair growth occurred after normalisation of chloroquine dosage. A discussion on possible pathomechanisms of this phenomenon is made based on experimental data and previously reported patients with the same condition.
Di Giacomo
T B
TB
Department of Dermatology, Hospital das Clínicas, University of Sao Paulo, Sao Paulo, Brazil. thabello@hotmail.com
Valente
N Y S
NY
Nico
M M S
MM
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002648:Child; D002738:Chloroquine / Q000009:adverse effects / Q000031:analogs & derivatives*; D003882:Dermatomyositis / Q000188:drug therapy; D062787:Drug Overdose; D006200:Hair Color; D006801:Humans; D017496:Hypopigmentation / Q000139:chemically induced*; D008297:Male
D000894:Anti-Inflammatory Agents, Non-Steroidal; C023676:chloroquine diphosphate; D002738:Chloroquine