Effects of intramuscular acepromazine and diazepam on tear production in rabbits.
Sixteen New Zealand white rabbits were divided randomly into two groups of eight. Schirmer II tear tests were performed on all 16 and then eight received an intramuscular dose of 1 mg/kg acepromazine and the other eight received an intramuscular dose of 1 mg/kg diazepam. The Schirmer tests were repeated after 15 and 25 minutes. There was a significant reduction in tear production by the rabbits treated with acepromazine, but no significant change in tear production by the rabbits treated with diazepam.
Ghaffari
M Selk
MS
Department of Clinical Studies, Islamic Azad University, Karaj, Iran. selkghaffari@gmail.com
Moghaddassi
A P
AP
Bokaie
S
S
D000075:Acepromazine / Q000494:pharmacology*; D000818:Animals; D003975:Diazepam / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D007273:Injections, Intramuscular / Q000662:veterinary; D009125:Muscle Relaxants, Central / Q000494:pharmacology*; D011817:Rabbits / Q000502:physiology*; D011897:Random Allocation; D013666:Tears / Q000187:drug effects* / Q000378:metabolism
D018492:Dopamine Antagonists; D009125:Muscle Relaxants, Central; D000075:Acepromazine; D003975:Diazepam