Primary central nervous system lymphoma after liver transplantation treated by radiosurgery combined with fractionated radiotherapy.
Post-transplant primary central nervous system lymphoma is a rare malignant tumor. A 65-year-old man underwent orthotopic liver transplantation for liver carcinoma. Nine months later, he presented with left-sided motor weakness and MRI of the brain showed a rim-enhancing mass in the right paracentral area. The diagnosis of Epstein-Barr virus-positive diffuse large B-cell lymphoma was confirmed through stereotactic biopsy. The authors report a case of post-transplant primary central nervous system lymphoma after liver transplantation that was treated successfully by gamma knife radiosurgery combined with fractionated whole brain radiotherapy.
Kim
Min-Su
MS
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea.
Lee
Jung-Il
JI
Kim
Won-Seok
WS
Ko
Yung-Hye
YH
D000368:Aged; D002277:Carcinoma / Q000601:surgery; D016543:Central Nervous System Neoplasms / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects; D008223:Lymphoma / Q000209:etiology / Q000628:therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D016634:Radiosurgery / Q000379:methods*; D011878:Radiotherapy / Q000379:methods*