title: Delayed enhancement cardiovascular magnetic resonance as a novel technique to predict cardiac events in dilated cardiomyopathy patients.
abstract: OBJECTIVE
  Delayed enhancement cardiovascular magnetic resonance (DE-CMR) can detect cardiac scarring and has the potential to visualize the progression of myocardial remodeling. We determined whether DE-CMR can predict cardiac events in dilated cardiomyopathy patients.
  
  
  METHODS
  Transthoracic echocardiography, coronary arteriography, and DE-CMR studies were performed in 60 consecutive dilated cardiomyopathy (DCM) patients. Percent delayed enhancement (%DE) was determined as the ratio of the area showing delayed enhancement to the total myocardial area in three short-axis views. Patients were classified as advanced group (Group A) when %DE was 10% or higher, and as non-advanced group (Group NA) when %DE was less than 10%. The incidence of cardiac events and the clinical history were compared between Group A and Group NA.
  
  
  RESULTS
  There were 11 patients in Group A and 49 patients in Group NA. The incidence of cardiac events was significantly higher in Group A (36%; 4/11 patients) than in Group NA (2.0%; 1/49 patients) (log rank, p=0.0001).
  
  
  CONCLUSIONS
  DE-CMR is a useful tool to predict cardiac events in DCM patients.
authors.affiliation: Sakakibara Heart Institute, Tokyo, Japan.
authors.forename: Ippei
authors.initials: I
authors.lastname: Shimizu
authors.forename: Nobuo
authors.initials: N
authors.lastname: Iguchi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Jun
authors.initials: J
authors.lastname: Umemura
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tobaru
authors.forename: Ryuta
authors.initials: R
authors.lastname: Asano
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Misu
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Nagayama
authors.forename: Masaru
authors.initials: M
authors.lastname: Aikawa
authors.forename: Nobusada
authors.initials: N
authors.lastname: Funabashi
authors.forename: Issei
authors.initials: I
authors.lastname: Komuro
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Sumiyoshi
mesh_terms: D000208:Acute Disease; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000453:epidemiology; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D020257:Ventricular Remodeling