title: Prediction of type 2 diabetes using alternate anthropometric measures in a multi-ethnic cohort: the insulin resistance atherosclerosis study.
abstract: OBJECTIVE
  To compare different anthropometric measures in terms of their ability to predict type 2 diabetes and to determine whether predictive ability was modified by ethnicity.
  
  
  METHODS
  Anthropometry was measured at baseline for 1,073 non-Hispanic white (nHW), African American (AA), and Hispanic (HA) subjects, of whom 146 developed type 2 diabetes after 5.2 years. Logistic regression models were used with areas under the receiver operator characteristic curve (AROCs) comparing the prediction of models.
  
  
  RESULTS
  Waist-to-height ratio (AROC 0.678) was the most predictive measure, followed by BMI (AROC 0.674). Results were similar in nHW and HA subjects, although in AA subjects, central adiposity measures appeared to best predict type 2 diabetes.
  
  
  CONCLUSIONS
  Measures of central and overall adiposity predicted type 2 diabetes to a similar degree, except in AA subjects, for whom results suggested that central measures were more predictive.
authors.affiliation: Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Meredith F
authors.initials: MF
authors.lastname: MacKay
authors.forename: Steven M
authors.initials: SM
authors.lastname: Haffner
authors.forename: Lynne E
authors.initials: LE
authors.lastname: Wagenknecht
authors.forename: Ralph B
authors.initials: RB
authors.lastname: D'Agostino
authors.forename: Anthony J G
authors.initials: AJ
authors.lastname: Hanley
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology*; D000328:Adult; D000368:Aged; D000886:Anthropometry; D050197:Atherosclerosis / Q000453:epidemiology*; D044383:Black People / Q000706:statistics & numerical data; D015992:Body Mass Index; D049628:Body Size; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005006:Ethnicity / Q000706:statistics & numerical data*; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D011237:Predictive Value of Tests; D012885:Skinfold Thickness; D013997:Time Factors; D044465:White People / Q000706:statistics & numerical data; D001741:Black or African American