[Influence of EDTA injection in the blood of the rat on the process of self-warming after deep hypothermia].
With the help of thermometry and general calorimetry, changes in the heat exchange were determined in rats upon their getting out of artificial deep hypothermia (the temperature in the rectum was 19-20 degrees C) at the temperature in the calorimeter chamber of 20 degrees C. In initial study of self-warming (the temperature in the rectum was 21-22 degrees C), the rats were injected with 1 ml 0.5% ethylenediaminetetraacetic acid disodium salt (EDTA) with purpose of speeding up the recovery to normal state. The experiments showed that EDTA increased the total heat production and kept in on high level during 3 hous. During that time, the rectal temperature of the rats was 37.6 +/- 0.6 degrees C in the end of the experiments, but in the control that value was only 35.1 +/- 0.5 degrees C.
Rumiantsev
G V
GV
Arokina
N K
NK
D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology*; D004492:Edetic Acid / Q000494:pharmacology*; D007035:Hypothermia / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012768:Shivering / Q000187:drug effects*
D000925:Anticoagulants; D004492:Edetic Acid