Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy.
Combined chemotherapy using carboplatin and paclitaxel has been established as a standard regimen for epithelial ovarian carcinoma. We present the case of a 36-year-old woman with ovarian mucinous cystadenocarcinoma who underwent exploratory laparotomy during pregnancy, revealing Stage 1c at gestational week 15. Afterwards, five courses of paclitaxel and carboplatin chemotherapy were administered biweekly from gestational week 24. Cesarean section was performed at gestational week 36. No recurrent or metastatic lesions were found and outcomes for both mother and neonate have been satisfactory for 40 months since diagnosis of ovarian carcinoma.
Doi
Daisuke
D
Department of Obstetrics and Gynecology, Musashikosugi Hospital, Nippon Medical School, 1-396 Kosugitchou, Nakaharaku, Kawasaki, Kanagawa, 211-0063, Japan. d-dtk@nms.ac.jp
Boh
Yumi
Y
Konishi
Hideki
H
Asakura
Hirobumi
H
Takeshita
Toshiyuki
T
D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols; D016190:Carboplatin / Q000627:therapeutic use*; D018282:Cystadenocarcinoma, Mucinous / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D017239:Paclitaxel / Q000627:therapeutic use*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*
D000972:Antineoplastic Agents, Phytogenic; D016190:Carboplatin; D017239:Paclitaxel