title: A breast fibroadenoma mimicking an extranodal deposit of Hodgkin's lymphoma in 67Ga imaging.
abstract: We present the case of a young woman with classical nodular sclerosing Hodgkin's lymphoma (clinical stage IIB). During staging work-up, intense gallium-67 ((67)Ga) accumulation in a left breast lump raised the suspicion of an extranodal deposit, but biopsy favoured a benign histology. A post-treatment (67)Ga scan showed complete remission of the disease with normal tracer uptake in the left breast. However, a few months after treatment, a faint left mammary concentration of (67)Ga was observed. The breast mass was excised and histopathology was consistent with fibroadenoma. This unusual presentation is a new addition to the literature on false-positive (67)Ga findings and chemotherapy-associated tracer changes.
authors.affiliation: Department of Nuclear Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece. emoral@hol.gr
authors.forename: E
authors.initials: E
authors.lastname: Moralidis
authors.forename: E
authors.initials: E
authors.lastname: Mandala
authors.forename: I
authors.initials: I
authors.lastname: Venizelos
authors.forename: G
authors.initials: G
authors.lastname: Arsos
authors.forename: E
authors.initials: E
authors.lastname: Zafiriadu
authors.forename: M
authors.initials: M
authors.lastname: Goutzioulis
authors.forename: C
authors.initials: C
authors.lastname: Karakatsanis
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D003287:Contrast Media; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005710:Gallium Radioisotopes; D006689:Hodgkin Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D008207:Lymphatic Metastasis; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003287:Contrast Media; D005710:Gallium Radioisotopes