title: Acute cholestatic hepatitis revealing Mycoplasma pneumoniae infection without lung involvement in an adult patient.
abstract: Liver involvement is an unusual manifestation of Mycoplasma pneumoniae infection. Cases of cholestatic hepatitis without pulmonary involvement have been described in children with M. pneumoniae infection but only two cases of cytolytic hepatitis have been reported in adults. We report here the case of an 18-year-old woman who presented with febrile epigastric pain of short duration associated with an elevation of gamma-glutamyl transpeptidase and alkaline phosphatase levels and with a mononuclear syndrome. Serological tests for M. pneumoniae were positive for IgG and IgM. Clinical symptoms and blood test perturbations completely resolved after treatment with macrolide.
authors.affiliation: Hepatology Unit, Cochin Hospital, Paris, France.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Quioc
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Trabut
authors.forename: François
authors.initials: F
authors.lastname: Drouhin
authors.forename: Claire
authors.initials: C
authors.lastname: Malbrunot
authors.forename: Anaïs
authors.initials: A
authors.lastname: Vallet-Pichard
authors.forename: Stanislas
authors.initials: S
authors.lastname: Pol
authors.forename: Jacques
authors.initials: J
authors.lastname: Denis
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002780:Cholestasis, Intrahepatic / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006505:Hepatitis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis* / Q000188:drug therapy; D015575:Roxithromycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D015575:Roxithromycin