Autosomal dominant polycystic kidney disease: emerging concepts of pathogenesis and new treatments.
Some of the mystery of autosomal dominant polycystic kidney disease (ADPKD) is starting to clear. Basic research is shedding light on its pathogenesis, and new treatments are in clinical trials. This paper reviews some of these advances and what they mean to patients.
Braun
William E
WE
Department of Nephrology and Hypertension, Transplantation Center, Glickman Urological and Kidney Institute, Q7, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
D000328:Adult; D005260:Female; D006801:Humans; D016891:Polycystic Kidney, Autosomal Dominant / Q000209:etiology / Q000628:therapy*