title: Successful use of terbutaline in persistent priapism in a 12-year-old boy with chronic myeloid leukemia.
abstract: A 12-year-old boy had been suffering from intermittent episodes of penile erection for 2 weeks. For the last 2 days, however, the patient had been having sustained priapism and had to be admitted in a private hospital for management. Investigations revealed high total leukocyte counts. He was referred to the authors' hospital where a diagnosis of chronic myeloid leukemia was made. He was started on intravenous hydration, hydroxyurea, and allopurinol. Imatinib was added 2 days later. The parents refused surgical intervention. Despite a reduction in the counts the priapism persisted and the pain was unresponsive to opioids. Administration of terbutaline was associated with a successful outcome resulting in relief from pain within 20 min. The priapism also resolved completely in 1 day.
authors.affiliation: Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India. ajayajaygupta2002@rediffmail.com
authors.forename: Ajay
authors.initials: A
authors.lastname: Gupta
authors.forename: Tulika
authors.initials: T
authors.lastname: Seth
authors.forename: Anuradha
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010146:Pain / Q000188:drug therapy; D011317:Priapism / Q000188:drug therapy* / Q000209:etiology; D013726:Terbutaline / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013726:Terbutaline