title: Pharmacokinetic study of S-1.
authors.affiliation: Department of Internal Medicine, University of Essen Medical School, Essen, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Mende
authors.forename: J
authors.initials: J
authors.lastname: Krauss
authors.forename: D
authors.initials: D
authors.lastname: Thyssen
authors.forename: S
authors.initials: S
authors.lastname: Kredtke
authors.forename: M E
authors.initials: ME
authors.lastname: Scheulen
authors.forename: D
authors.initials: D
authors.lastname: Strumberg
authors.forename: A
authors.initials: A
authors.lastname: Hanauske
authors.forename: L
authors.initials: L
authors.lastname: Makris
authors.forename: P
authors.initials: P
authors.lastname: Scigalla
authors.forename: P D
authors.initials: PD
authors.lastname: Urrea
authors.forename: R A
authors.initials: RA
authors.lastname: Hilger
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000008:administration & dosage; D000284:Administration, Oral; D000897:Anti-Ulcer Agents / Q000008:administration & dosage; D000964:Antimetabolites, Antineoplastic / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D019540:Area Under Curve; D001682:Biological Availability; D002986:Clinical Trials as Topic; D042943:Dihydrouracil Dehydrogenase (NADP) / Q000097:blood; D004338:Drug Combinations; D005215:Fasting; D005472:Fluorouracil / Q000031:analogs & derivatives / Q000378:metabolism; D005502:Food; D005745:Gastric Acidity Determination; D006207:Half-Life; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010094:Oxonic Acid / Q000097:blood / Q000378:metabolism / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D000077402:Pantoprazole; D011725:Pyridines / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use; D005641:Tegafur / Q000097:blood / Q000378:metabolism / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D014227:Triazines / Q000378:metabolism; D014498:Uracil / Q000031:analogs & derivatives / Q000378:metabolism; D015091:beta-Alanine / Q000031:analogs & derivatives / Q000378:metabolism
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; D014227:Triazines; C007419:dihydrouracil; D015091:beta-Alanine; C079198:S 1 (combination); D005641:Tegafur; C032348:alpha-fluoro-beta-alanine; C489337:potassium oxonate; D014498:Uracil; D010094:Oxonic Acid; C019389:5-fluorodihydrouracil; D000077402:Pantoprazole; D042943:Dihydrouracil Dehydrogenase (NADP); C004632:cyanuric acid; D005472:Fluorouracil; C104201:gimeracil