title: Bone fracture: an unusual presentation of acute megakaryoblastic leukemia.
abstract: Some clinical manifestations of acute leukemia in children can mimic orthopedic conditions, and t is variable presentation often makes diagnosis difficult. Bone changes in leukemia are well documented, but there are only a few accounts of children with acute leukemia who present with bone fractures. This report describes a case of this rare combination in a very young boy who presented with fractures of both proximal humerus and left proximal femur and massive periosteal reactions of both humerus and femur and also cystic lesions of proximal femur and iliac bone accompanying aggressive acute megakaryoblastic leukemia.
authors.affiliation: Baskent University Faculty of Medicine, Department of Pediatric Hematology, Ankara, Turkey. alioglub@gmail.com
authors.forename: Bulent
authors.initials: B
authors.lastname: Alioglu
authors.forename: Ismail Cengiz
authors.initials: IC
authors.lastname: Tuncay
authors.forename: Emel
authors.initials: E
authors.lastname: Ozyurek
authors.forename: Zekai
authors.initials: Z
authors.lastname: Avci
authors.forename: Namik
authors.initials: N
authors.lastname: Ozbek
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005264:Femoral Fractures; D050723:Fractures, Bone / Q000209:etiology*; D006801:Humans; D006810:Humeral Fractures; D007947:Leukemia, Megakaryoblastic, Acute / Q000150:complications* / Q000473:pathology; D008297:Male; D010521:Periosteum