[Particularities of the association of systemic arterial hypertension in patients with sleep apnea syndrome].
OBJECTIVE
Analysis of the association between sleep apnea syndrome (SAS) and systemic hypertension (SHT) in consecutive patients with suspicion of SAS.


METHODS
We included 427 consecutive patients evaluated for SAS at Babes University Sleep Lab, Timisoara (March 2001-March 2007). Medical history, anthropometric measurements, cardiovascular evaluation, inclusion/exclusion criteria, Epworth scale, polysomnography, statistical analysis with STATA 9.2. were done.


RESULTS
Systemic hypertension (SHT) at 245 (58,05%) of patients, pre-SHT at 11,37%, stage I 11,37%, stage II 29,14%, stage III 6,16%, onset of disease 7,26 +/- 6,13 years. Differences between groups without and with SHT: apnea-hypopnea index (AHI) 27,71 +/- 27,94/h, CI 23,55-31,78 vs 38,6 +/- 26,16/h, CI 35,34-41,85, p < 0,001, body mass index (BMI) 31,43 +/- 6,26 kg/m2, CI 30,50-32,36 vs 34,21 +/- 6,11 kg/m2, CI 33,45- 34,97 p < 0,001, desaturation index 20,21 +/- 26,35/h, CI 16,28-24,13 vs 31,12 +/- 29,16 CI 27,49-34,75, p < 0,001, medium desaturation 92,93 +/- 5,03%, CI 92,18-93,68 vs. 90,6 +/- 8,42, CI 89,55-91,64, p < 0,001, medium age 47,66 +/- 12,57 years, CI 45,79-49,52 vs. 55,06 +/- 10,35 years, CI 53,77-56,35, p = 0,0047, abdominal circumference 117,77 +/- 15,44 cm, CI 115,48-120,06 vs. 121,68 +/- 14,66 cm, CI 119,85-123,51, p = 0,0082, neck circumference 42,98 +/- 4,84 cm, CI 42,26-43,70 vs. 44,24 +/- 4.59 cm, CI 43,67-44,81 p = 0,0068, Epworth score 9,09 +/- 4,81, CI 8,37-9,80 vs. 10,77 +/- 5,19, CI 10,12-11,42, p = 0,007.


CONCLUSIONS
SHT represents the most frequent disease association in SAS patients. Differences between groups without and with SHT were statistical significant in apnea--hypopnea index, body mass index, desaturation index, medium desaturation, age, abdominal circumference, neck circumference, Epworth score.
Mihăicuţă
Stefan
S
Clinica de Pneumologie, UMF V. Babeş Timişoara. mihaicuta@yahoo.com
Ursoniu
Sorin
S
Lighezan
Daniel
D
Muntean
Danina
D
Firă-Mlădinescu
Ovidiu
O
Horhat
Raul
R
Frenţ
Stefan
S
Gaiţă
Dan
D
Tudorache
Voicu
V
D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000886:Anthropometry; D015992:Body Mass Index; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000175:diagnosis*
D010100:Oxygen