Light scattering spectroscopy of human skin in vivo.
We present an in vivo study of the reduced scattering coefficient of normal skin and of common melanocytic nevi in Caucasian subjects. The spectral shape of the reduced scattering coefficient is described well by a power-law dependence on the wavelength, in accordance with previous studies of light scattering by biological tissues. We investigate statistical variations in the scattering spectrum slope and also identify an inherent correlation between scattering intensity and scattering spectral slope, observed mainly in normal skin. In addition, we do not find any significant differences between the scattering properties of normal skin and common melanocytic nevi. Finally, we also provide a short review of previously published studies reporting on the light scattering properties of human skin both in vivo and in vitro.
Zonios
George
G
Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece. gzonios@alum.mit.edu
Dimou
Aikaterini
A
D000328:Adult; D004058:Diffusion; D006801:Humans; D008027:Light; D008544:Melanocytes / Q000473:pathology; D009506:Nevus / Q000503:physiopathology; D012542:Scattering, Radiation; D012879:Skin Physiological Phenomena / Q000528:radiation effects*; D013057:Spectrum Analysis