title: Mortality profiles in a country facing epidemiological transition: an analysis of registered data.
abstract: BACKGROUND
  Sub-national analyses of causes of death and time-trends help to define public health policy priorities. They are particularly important in countries undergoing epidemiological transition like Peru. There are no studies exploring Peruvian national and regional characteristics of such epidemiological transition. We aimed to describe Peru's national and regional mortality profiles between 1996 and 2000.
  
  
  METHODS
  Registered mortality data for the study period were corrected for under-registration following standardized methods. Main causes of death by age group and by geographical region were determined. Departmental mortality profiles were constructed to evaluate mortality transition, using 1996 data as baseline. Annual cumulative slopes for the period 1996-2000 were estimated for each department and region.
  
  
  RESULTS
  For the study period non-communicable diseases explained more than half of all causes of death, communicable diseases more than one third, and injuries 10.8% of all deaths. Lima accounted for 32% of total population and 20% of total deaths. The Andean region, with 38% of Peru's population, accounted for half of all country deaths. Departmental mortality predominance shifted from communicable diseases in 1996 towards non-communicable diseases and injuries in 2000. Maternal and perinatal conditions, and nutritional deficiencies and nutritional anaemia declined markedly in all departments and regions. Infectious diseases decreased in all regions except Lima. In all regions acute respiratory infections are a leading cause of death, but their proportion ranged from 9.3% in Lima and Callao to 15.3% in the Andean region. Tuberculosis and injuries ranked high in Lima and the Andean region.
  
  
  CONCLUSIONS
  Peruvian mortality shows a double burden of communicable and non-communicable, with increasing importance of non-communicable diseases and injuries. This challenges national and sub-national health system performance and policy making.
authors.affiliation: Department of Paediatrics, Universidad Nacional Mayor de San Marcos, Lima, Peru. lhuicho@gmail.com
authors.forename: Luis
authors.initials: L
authors.lastname: Huicho
authors.forename: Miguel
authors.initials: M
authors.lastname: Trelles
authors.forename: Fernando
authors.initials: F
authors.lastname: Gonzales
authors.forename: Walter
authors.initials: W
authors.lastname: Mendoza
authors.forename: Jaime
authors.initials: J
authors.lastname: Miranda
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death / Q000639:trends*; D046688:Child Mortality / Q000639:trends*; D002675:Child, Preschool; D002908:Chronic Disease; D003141:Communicable Diseases / Q000453:epidemiology / Q000401:mortality*; D003906:Developing Countries; D004066:Digestive System Diseases / Q000401:mortality; D005260:Female; D014943:Global Health; D006306:Health Surveys; D006801:Humans; D007223:Infant; D007226:Infant Mortality / Q000639:trends; D007231:Infant, Newborn; D008017:Life Expectancy / Q000639:trends*; D008297:Male; D015999:Multivariate Analysis; D009369:Neoplasms / Q000401:mortality; D009748:Nutrition Disorders / Q000401:mortality; D010568:Peru / Q000453:epidemiology; D011203:Poverty; D015995:Prevalence; D011336:Probability; D011634:Public Health; D012042:Registries; D018570:Risk Assessment; D014376:Tuberculosis / Q000401:mortality