title: Atheroscerlotic heart disease in Bangladeshi immigrants: risk factors and angiographic findings.
abstract: BACKGROUND
  The prevalence of coronary artery disease (CAD) among Bangladeshis greatly exceeds that of Caucasians. Bangladeshis also suffer from premature onset, clinically aggressive and angiographically extensive disease. The role of conventional CAD risk factors (CCRFs) has been questioned. We therefore sought to determine if the CCRFs of Bangladeshis differed from non-Bangladeshis. We also sought to determine whether CAD was more extensive in Bangladeshis and if Bangladeshi ethnicity was independently predictive of extensive i.e., 3-vessel CAD at angiography.
  
  
  METHODS
  We reviewed the coronary angiograms and medical records of 75 Bangladeshis and 57 non-Bangladeshis presenting with myocardial infarction or angina pectoris.
  
  
  RESULTS
  Bangladeshis were younger (56.1 vs. 62.4 years, p=.001), had a lower body-mass index (25.2 vs. 27.2 kg/m(2), p=.017) and were less likely to be current or recent smokers (40% vs. 58%, p=.041) than non-Bangladeshis. There were no statistically significant differences in the proportion of subjects in the 2 groups with respect to diabetes mellitus, dyslipidemia, hypertension or family history of CAD. Bangladeshis had twice the rate of 3-vessel CAD of non-Bangladeshis (53% vs. 26%, p=.002). Bangladeshi ethnicity was independently associated with >3X the likelihood of having 3-vessel CAD at angiography (p=.011).
  
  
  CONCLUSIONS
  This study demonstrated that the CCRF burden of Bangladeshis with CAD is not excessive compared to that of non-Bangladeshis and is therefore unlikely to account for the excessive CAD risk found in this cohort. We also conclude that Bangladeshis have more angiographically extensive CAD than non-Bangladeshis and that Bangladeshi ethnicity is independently predictive of 3-vessel disease.
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Silbiger
authors.forename: Ramin
authors.initials: R
authors.lastname: Ashtiani
authors.forename: Mehran
authors.initials: M
authors.lastname: Attari
authors.forename: Tanya M
authors.initials: TM
authors.lastname: Spruill
authors.forename: Mazullah
authors.initials: M
authors.lastname: Kamran
authors.forename: Deborah
authors.initials: D
authors.lastname: Reynolds
authors.forename: Russell
authors.initials: R
authors.lastname: Stein
authors.forename: David
authors.initials: D
authors.lastname: Rubinstein
mesh_terms: D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data*; D001459:Bangladesh / Q000208:ethnology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D014481:United States / Q000453:epidemiology