Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates.
A simple, chemoselective transfer hydrogenation of aryl aldehydes with the aid of Amberlite((R)) resin formate (ARF), a stable H-donor, in the presence of catalytic ruthenium trichloride is described. Aromatic aldehydes and 1,2-diketones are reduced efficiently and selectively, while aryl ketones remain unchanged. Several other potentially reducible groups attached to the aromatic moiety are unaffected.
Basu
Basudeb
B
Department of Chemistry, University of North Bengal, Darjeeling 734 013, India. basu_nbu@hotmail.com
Mandal
Bablee
B
Das
Sajal
S
Das
Pralay
P
Nanda
Ashis K
AK