Multifocal osteomyelitis caused by Candida dubliniensis.
Candida dubliniensis is an emerging fungal pathogen, especially in immunodeficient patients. We report what is to the best of our knowledge the first case of multifocal osteomyelitis following disseminated infection in a patient after haematopoietic stem cell transplantation. PFGE for typing of C. dubliniensis was developed and the necessity of long-term antifungal therapy is discussed.
Wellinghausen
Nele
N
Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Ulm, Germany.
Moericke
Angelika
A
Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Ulm, Germany.
Bundschuh
Silke
S
University Hospital for Children's and Adolescent Medicine, Ulm, Germany.
Friedrich
Wilhelm
W
University Hospital for Children's and Adolescent Medicine, Ulm, Germany.
Schulz
Ansgar S
AS
University Hospital for Children's and Adolescent Medicine, Ulm, Germany.
Gatz
Susanne A
SA
University Hospital for Children's and Adolescent Medicine, Ulm, Germany.
D000745:Anemia, Hemolytic, Congenital / Q000150:complications / Q000276:immunology / Q000628:therapy; D000908:Antibodies, Fungal / Q000097:blood; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D021821:Communicable Diseases, Emerging / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012150:Polymorphism, Restriction Fragment Length; D016499:Radioimmunotherapy / Q000009:adverse effects; D012867:Skin / Q000382:microbiology; D013977:Tibia / Q000382:microbiology; D016896:Treatment Outcome; D055815:Young Adult
D000908:Antibodies, Fungal; D000935:Antifungal Agents