title: Triacylglycerol metabolism in adipose tissue.
abstract: Triacylglycerol (TAG) in adipose tissue serves as the major energy storage form in higher eukaryotes. Obesity, resulting from excess white adipose tissue, has increased dramatically in recent years resulting in a serious public health problem. Understanding of adipocyte-specific TAG synthesis and hydrolysis is critical to the development of strategies to treat and prevent obesity and its closely associated diseases, for example, Type 2 diabetes, hypertension and atherosclerosis. In this review, we present an overview of the major enzymes in TAG synthesis and lipolysis, including the recent discovery of a novel adipocyte TAG hydrolase.
authors.affiliation: University of California, Department of Nutritional Sciences & Toxicology, Berkeley, CA 94720, USA, Tel.: +1 510 642 3978; ; mahmadia@berkeley.edu.
authors.forename: Maryam
authors.initials: M
authors.lastname: Ahmadian
authors.forename: Robin E
authors.initials: RE
authors.lastname: Duncan
authors.forename: Kathy
authors.initials: K
authors.lastname: Jaworski
authors.forename: Eszter
authors.initials: E
authors.lastname: Sarkadi-Nagy
authors.forename: Hei Sook
authors.initials: HS
authors.lastname: Sul