title: A rare case of intussusception leading to the diagnosis of acquired immune deficiency syndrome: a case report.
abstract: BACKGROUND
  Although a common cause of intestinal obstruction in children, intussusception is a rare event in the adult population living in temperate regions. It has long been known that various acquired immune deficiency syndrome related conditions of the bowel such as lymphoma, lymphoid hyperplasia, cytomegalovirus colitis and Kaposi's sarcoma can lead to intussusception. The diagnosis is particularly difficult in this population of patients due to the non-specific nature of the symptoms as well as the depressed immune response obscuring inflammation or ischemia. Though the reported acquired immune deficiency syndrome associated cases of intussusception refer to patients with known human immunodeficiency virus infection, in our case we present an intestinal intussusception as the first manifestation of human immunodeficiency virus infection.
  
  
  METHODS
  A 58-year-old white heterosexual Greek man with a clean medical record and no history of abdominal operation presented to the emergency department with symptoms and signs of bowel obstruction. Plain abdominal radiographs were highly suspicious for intussusception which was eventually confirmed on a computed tomography scan. Due to the patients clean medical record as well as the radiologic diagnosis of intussusception, we promptly undertook further serologic tests for human immunodeficiency virus and eventually established the diagnosis of acquired immune deficiency syndrome. The patient was operated 3 days later and this confirmed the diagnosis of small-bowel invagination due to a 4 cm polypoid growing intraluminal tumor, the pathologic examination of which revealed a diffuse high-grade B cell lymphoblastic lymphoma.
  
  
  CONCLUSIONS
  Human immunodeficiency virus infection may have a silent course and gastrointestinal manifestations of the disease leading to intussusception might be the first clinical sign. Patients with intestinal intussusception, and the presence of risk factors for human immunodeficiency virus infection should be eligible for serologic tests for human immunodeficiency virus infection.
authors.affiliation: Department of Surgery, School of Medicine, University of Patras, Rion University Hospital, 26500, Patras, Greece. ikehag@yahoo.gr.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kehagias
authors.forename: Stavros N
authors.initials: SN
authors.lastname: Karamanakos
authors.forename: Spyros
authors.initials: S
authors.lastname: Panagiotopoulos
authors.forename: Sofia
authors.initials: S
authors.lastname: Giali
authors.forename: Charalambos A
authors.initials: CA
authors.lastname: Gogos
authors.forename: Fotis
authors.initials: F
authors.lastname: Kalfarentzos