Anti-Lewis alloimmunization: report of seven cases.
OBJECTIVE
The purpose of this study was to investigate the perinatal results of seven pregnant women with anti-Lewis antibodies and evaluate the need to screen for these antigens during routine prenatal care.


METHODS
São Paulo Universtity Hospital, São Paulo, Brazil.


METHODS
200 Rh-negative pregnant women with a positive indirect Coombs test, managed during a 6-year period.


METHODS
The charts of all patients were reviewed to collect pertinent data and the variables were analyzed.


METHODS
Indirect Coombs test titer, intrauterine transfusion, mode of delivery, gestational age at birth, birthweight, neonatal transfusion, duration of neonatal hospitalization and perinatal mortality.


RESULTS
All newborn infants were classified as adequate for gestational age at birth and none needed intrauterine or neonatal transfusions. All infants, except one, were discharged in good health on the third day after birth.


CONCLUSIONS
Alloimmunized pregnancies (Levis antigens) have good perinatal results.
Nardozza
L M M
LM
Fetal Medicine Sector, Obstetrics Department, São Paulo Federal University-Paulista Medical School, São Paulo, Brazil. lunardozza@ud.com.br
Lobo
G R
GR
Moron
A F
AF
Camano
L
L
Araujo Júnior
E
E
Araujo
E
E
Guimarães Filho
H A
HA
D015331:Cohort Studies; D003298:Coombs Test; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000276:immunology*; D007983:Lewis Blood Group Antigens / Q000276:immunology*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies
D007518:Isoantibodies; D007983:Lewis Blood Group Antigens