Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns.
Stem cell researchers commonly use human pluripotent stem cell lines derived by other investigators. Researchers may use lines derived elsewhere, provided that their derivation met consensus core standards. Some types of derivation raise heightened levels of ethical concern and require greater scrutiny. To maintain public trust, research institutions need to justify why they allow researchers to use lines whose derivation would not have been permitted locally.
Lo
Bernard
B
Program in Medical Ethics, University of California-San Francisco, San Francisco, CA 94143, USA. bernard.lo@ucsf.edu
Parham
Lindsay
L
Broom
Christopher
C
Cedars
Marcelle
M
Gates
Elena
E
Giudice
Linda
L
Halme
Dina Gould
DG
Hershon
William
W
Kriegstein
Arnold
A
Kwok
Pui-yan
PY
Oberman
Michelle
M
Roberts
Clifford
C
Wagner
Richard
R
D000818:Animals; D002460:Cell Line; D019924:Embryo Disposition; D033041:Embryo Research / Q000191:economics / Q000941:ethics / Q000331:legislation & jurisprudence; D006801:Humans; D007391:International Cooperation; D009865:Oocytes / Q000502:physiology; D039904:Pluripotent Stem Cells