Solvent-induced high fidelity switching between two discrete supramolecules.
Here we show the reversible high fidelity switching between two discrete self-assembled supramolecules made from a lipophilic 8-phenyl-2'-deoxyguanosine derivative induced by an indirect solvent effect. A hexadecameric supramolecule containing four stacked tetramers is formed in acetonitrile aided by higher potassium concentrations. When the amount of weakly solvated potassium decreases, due the lower activity of potassium iodide in chloroform, an octamer is formed after the dissociation of the two outer tetramers in the hexadecamer. The switching process results from an unprecedented subtle interplay between the activity of potassium iodide and the steric crowding within the self-assembled structure. Besides the possible applications in nanoconstruction, this phenomenon sheds light into the mechanism of formation of self-assembled supramolecules made from guanosine derivatives.
Betancourt
José E
JE
Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, Rio Piedras, Puerto Rico 00931.
Martín-Hidalgo
Mariana
M
Gubala
Vladimir
V
Rivera
José M
JM
D000097:Acetonitriles / Q000737:chemistry*; D002725:Chloroform / Q000737:chemistry*; D006151:Guanosine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D006860:Hydrogen Bonding; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry
D000097:Acetonitriles; D046911:Macromolecular Substances; D012997:Solvents; D006151:Guanosine; D002725:Chloroform