title: Left ventricular functional analysis with 16- and 64-row multidetector computed tomography: comparison with gated single-photon emission computed tomography.
abstract: OBJECTIVE
  To compare the left ventricular (LV) ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volume (ESV) from electrocardiogram-gated computed tomography (CT) to gated single-photon emission computed tomography (SPECT).
  
  
  METHODS
  Fifty-seven patients underwent electrocardiogram-gated multidetector CT and SPECT examinations within a 3-month period, without interim cardiac events. The LV EF, EDV, and ESV were compared.
  
  
  RESULTS
  There was an excellent correlation between LV EF obtained from CT (60.25% +/- 12.93%) and SPECT (61.90% +/- 14.93%) (r = 0.81), with no significant difference (P = 0.17). Computed tomography-derived EDV and ESV correlated well with SPECT (r = 0.88 and 0.94, respectively). The EDV from SPECT (132.21 +/- 67.10 mL) was significantly lower than that from CT (147.53 +/- 55.03 mL; P = 0.0007); there was a trend for ESV from SPECT (58.39 +/- 61.20 mL) to be lower than that from CT (63.79 +/- 53.58 mL; P = 0.055). The EF, EDV, and ESV correlation of SPECT with the 64-row multidetector CT was better (r = 0.87, 0.89, and 0.96, respectively) than that with the 16-row CT (r = 0.36, 0.66, and 0.49, respectively).
  
  
  CONCLUSIONS
  There is a good correlation between LV EF, EDV, and ESV from gated SPECT and CT (particularly the 64-row CT). The LV volumes are lower on SPECT than on CT.
authors.affiliation: Division of Cardiothoracic Radiology, Department of Radiology, University of Michigan Hospitals, Ann Arbor, MI 48109-0030, USA. prachia@med.umich.edu
authors.forename: Prachi P
authors.initials: PP
authors.lastname: Agarwal
authors.forename: Smita
authors.initials: S
authors.lastname: Patel
authors.forename: James
authors.initials: J
authors.lastname: Corbett
authors.forename: Jung Im
authors.initials: JI
authors.lastname: Jung
authors.forename: Karen
authors.initials: K
authors.lastname: Barber
authors.forename: Matthew
authors.initials: M
authors.lastname: Schipper
authors.forename: Ella A
authors.initials: EA
authors.lastname: Kazerooni
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000209:etiology