A last-minute rescue of trapped chromatin.
Chromosome segregation and cytokinesis must be tightly coordinated to ensure that chromosomes are accurately partitioned between dividing cells. In this issue, Steigemann et al. (2009) report that Aurora B kinase promotes proper chromosome segregation by delaying abscission when chromatin is trapped between dividing cells.
Chen
Chun-Ting
CT
University of Massachusetts Medical School, Program in Molecular Medicine, Worcester, MA 01655, USA.
Doxsey
Stephen
S
D000818:Animals; D064107:Aurora Kinase B; D064127:Aurora Kinases; D002843:Chromatin / Q000378:metabolism*; D020090:Chromosome Segregation; D006801:Humans; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*
D002843:Chromatin; C576921:AURKB protein, human; D064107:Aurora Kinase B; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases