Vacations to waterside locations result in nevus development in Colorado children.
Nevi are a main risk factor for malignant melanoma, and most nevi develop in childhood. This study examined the relationship between vacations and nevi in 681 White children born in 1998 who were lifetime residents of Colorado. Vacation histories were assessed through telephone interviews of parents, whereas nevus and phenotypic characteristics were assessed through skin exams at age 7. Multiple linear and logistic regression were used to assess the influence of vacations on counts of nevi <2 mm in size and the presence of any nevi > or = 2 mm after controlling for other variables. Each waterside vacation > or = 1 year before the exam at age 7 was found to be associated with a 5% increase in nevi <2 mm. Waterside vacations <1 year before the skin exam were not related to nevus count (<2 mm); regardless of timeframe, waterside vacations were not related to the presence of nevi > or = 2 mm. UV dose received on waterside vacations, number of days spent on waterside vacations, and nonwaterside vacations were not significantly related to nevi <2 or > or = 2 mm. These results suggest that there is a lag of at least 1 year in the development of new nevi after vacation sun exposure. It appears that a threshold dose of UV exposure is received quickly on each waterside vacation. Parents of young children should exercise caution in selection of vacation locations to reduce melanoma risk.
Pettijohn
Kelly J
KJ
Department of Community and Behavioral Health, Colorado School of Public Health, Aurora, CO 80045, USA.
Asdigian
Nancy L
NL
Aalborg
Jenny
J
Morelli
Joseph G
JG
Mokrohisky
Stefan T
ST
Dellavalle
Robert P
RP
Crane
Lori A
LA
D000704:Analysis of Variance; D002648:Child; D003120:Colorado / Q000453:epidemiology; D005260:Female; D005618:Fresh Water; D006801:Humans; D007407:Interviews as Topic; D007899:Leisure Activities; D008297:Male; D009508:Nevus, Pigmented / Q000453:epidemiology / Q000209:etiology*; D010641:Phenotype; D010808:Physical Examination; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology*; D013471:Sunburn / Q000150:complications / Q000453:epidemiology; D014466:Ultraviolet Rays / Q000009:adverse effects*; D044465:White People