[Epithelioid angiomyolipoma of the kidney].
A 37-year-old female was referred to our department for a renal mass which was incidentally found during a medical check-up. She had no history of tuberous sclerosis. Computed tomography and magnetic resonance imaging showed a 1.5-cm enhancing mass at the lower pole of the left kidney. An open partial nephrectomy was performed for a pre-operative diagnosis of renal cell carcinoma. Pathological examination revealed sheets of large polygonal epithelioid cells that showed positive immunostaining for HMB-45, which confirmed the diagnosis of an epithelioid angiomyolipoma. The patient remained free of recurrent or metastatic disease at 3 months of follow-up. Epithelioid angiomyolipoma is a recently identified variant of angiomyolipoma, which is sometimes associated with aggressive clinical behavior including local recurrence and metastasis. We present this case and review the literature concerning this unusual disorder.
Kaneko
Tomoyuki
T
Department of Urology, Toshiba Hospital.
Kashibuchi
Keishi
K
Asakage
Yasuyuki
Y
Homma
Yukio
Y
D000328:Adult; D018207:Angiomyolipoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000032:analysis; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins