Prolonged survival of a patient with AIDS and central nervous system aspergillosis.
In HIV-infected patients, central nervous system (CNS) aspergillosis is rare. Historically, the outcome of such infections has been almost invariably fatal. We report a case involving an AIDS patient with an Aspergillus fumigatus brain abscess who survived for longer than 10 months after surgical drainage and therapy with voriconazole.
Hidron
Alicia I
AI
Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Gongora
Maria C
MC
Anderson
Albert M L
AM
Diazgranados
Carlos A
CA
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D001921:Brain / Q000473:pathology; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D011743:Pyrimidines / Q000627:therapeutic use; D011859:Radiography; D013534:Survival; D013997:Time Factors; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole