title: True osseous metaplasia of the endometrium: the bone is not from a fetus.
abstract: OBJECTIVE
  To identify the origin of calcified tissue in endometrial ossification.
  
  
  METHODS
  DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes.
  
  
  METHODS
  University and general hospitals.
  
  
  METHODS
  A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium.
  
  
  METHODS
  Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis.
  
  
  METHODS
  DNA comparison between the patient and the osseous tissue extracted from the uterus.
  
  
  RESULTS
  All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin.
  
  
  CONCLUSIONS
  Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.
authors.affiliation: Obstetrics and Gynecology Department, Hospital General Hospitalet, Barcelona, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Cayuela
authors.forename: Tirso
authors.initials: T
authors.lastname: Perez-Medina
authors.forename: Joan
authors.initials: J
authors.lastname: Vilanova
authors.forename: Maria
authors.initials: M
authors.lastname: Alejo
authors.forename: Paz
authors.initials: P
authors.lastname: Cañadas
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects; D000328:Adult; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology*; D003937:Diagnosis, Differential; D004717:Endometrium / Q000473:pathology*; D005260:Female; D005333:Fetus / Q000378:metabolism / Q000473:pathology*; D005838:Genotype; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000209:etiology; D008679:Metaplasia / Q000175:diagnosis / Q000235:genetics; D009999:Ossification, Heterotopic / Q000175:diagnosis* / Q000235:genetics