title: Physical and psychosexual pubertal development: physiology and pathophysiology of puberty with lessons learned from those with disorders of sex development.
abstract: This review updates information concerning control of puberty, diagnosis and treatment of precocious puberty and behavioral changes, which appear to be related to environmental changes, rather than physical timing of changes. The relative role of hormone exposure during fetal life or later are still unclear.
authors.affiliation: Department of Pediatrics, Penn State College of Medicine, The Milton S. Hershey, Medical Center, Hershey, PA 17033-0850, USA. plee@psu.edu
authors.forename: Peter A
authors.initials: PA
authors.lastname: Lee
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Houk
mesh_terms: D001921:Brain / Q000187:drug effects / Q000502:physiology / Q000503:physiopathology; D012734:Disorders of Sex Development / Q000503:physiopathology* / Q000523:psychology*; D012739:Gonadal Steroid Hormones / Q000494:pharmacology; D006801:Humans; D008954:Models, Biological; D011606:Psychosexual Development / Q000502:physiology*; D011627:Puberty / Q000502:physiology* / Q000523:psychology*; D011629:Puberty, Precocious / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D012733:Sex Differentiation / Q000187:drug effects / Q000502:physiology; D012741:Sexual Maturation / Q000502:physiology*
chemical_list: D012739:Gonadal Steroid Hormones