[Parkinsonism during lithium use].
Two patients with bipolar disorder had been treated for years with lithium without any complications but began to develop symptoms of rigidity and an altered gait, namely symptoms compatible with a diagnosis of Parkinsonism with an action tremor. In both patients lithium levels were within the therapeutic range. Medication-induced Parkinsonism occurs frequently in patients using antipsychotic medication, but is a rare complication in patients receiving long term treatment with lithium. The lithium dosage was reduced gradually and within a few months all neurological symptoms subsided completely.
Walrave
T R W M
TR
t.walrave@zgt.nl
Bulens
C
C
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy; D004409:Dyskinesia, Drug-Induced / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D018020:Lithium Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000453:epidemiology; D015995:Prevalence
D014150:Antipsychotic Agents; D018020:Lithium Compounds