title: Cauda equina compression by hydrogel dural sealant after a laminotomy and discectomy: case report.
abstract: METHODS
  The authors present a case of cauda equina compression after laminotomy and discectomy where incidental durotomy was managed with the application of hydrogel sealant. The patient reported return of radicular symptoms on the first postoperative day, and deterioration to early cauda equina syndrome after bending on the sixth day.
  
  
  OBJECTIVE
  To demonstrate that in addition to its recognized volume expansion properties, that the product has the ability to migrate and produce symptoms remote from where it was inserted.
  
  
  BACKGROUND
  The physical properties of DuraSeal (Confluent Surgical, Waltham, MA), a hydrogel dural sealant, make it an effective adjunct to dural closure. Its volume expansion has been associated with neural compression after posterior fossa decompression. We have found no reported migration of this product.
  
  
  METHODS
  Sequential postoperative imaging shows swelling and migration of the hydrogel into spinal canal with resultant compression. Exploration on postoperative day 10 revealed sealant causing cauda equina compression proximal to the site of the durotomy.
  
  
  CONCLUSIONS
  The authors recommend that in addition to caution regarding its potential mass effect, that cognizance be taken of the product's potential to migrate and result in symptoms at a distant site.
authors.affiliation: Department/Division of Orthopaedic Surgery, Princess Alice Orthopaedic unit, Christiaan Barnard Memorial Hospital, Cape Town, South Africa. mike_rosemulder@telkomsa.net
authors.forename: Mike
authors.initials: M
authors.lastname: Mulder
authors.forename: J
authors.initials: J
authors.lastname: Crosier
authors.forename: R
authors.initials: R
authors.lastname: Dunn
mesh_terms: D001843:Bone Cements / Q000009:adverse effects*; D002420:Cauda Equina / Q000187:drug effects* / Q000473:pathology / Q000601:surgery; D017586:Diskectomy; D005548:Foreign-Body Migration / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007796:Laminectomy; D017116:Low Back Pain / Q000473:pathology / Q000601:surgery; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011843:Radiculopathy / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D012117:Resins, Synthetic / Q000009:adverse effects*; D013117:Spinal Cord Compression / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D012117:Resins, Synthetic; C030189:Dura-Seal