title: Molecular mechanisms of traumatic brain injury: the missing link in management.
abstract: Head injury is common, sometimes requires intensive care unit admission, and is associated with significant mortality and morbidity. A gap still remains in the understanding of the molecular mechanism of this condition. This review is aimed at providing a general overview of the molecular mechanisms involved in traumatic brain injury to a busy clinician. It will encompass the pathophysiology in traumatic brain injury including apoptosis, the role of molecules and genes, and a brief mention of possible pharmacological therapies.
authors.affiliation: Department of Anaesthesia and Intensive Care, Cambridge University Hospitals NHS Trust Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK. rowan.burnstein@addenbrookes.nhs.uk.
authors.forename: Tonny
authors.initials: T
authors.lastname: Veenith
authors.forename: Serena Sh
authors.initials: SSh
authors.lastname: Goon
authors.forename: Rowan M
authors.initials: RM
authors.lastname: Burnstein