title: Infection with hepatitis C virus among HIV-infected pregnant women in Thailand.
abstract: OBJECTIVE
  The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women.
  
  
  METHODS
  Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV.
  
  
  RESULTS
  Among HIV-infected pregnant women, HCV seroprevelance was 3.8% and the active HCV infection rate was 3.0%. Among HIV-uninfected pregnant women, 0.3% were HCV-infected. Intravenous drug use by the woman was the factor most strongly associated with HCV seropositivity. Among 48 infants tested for HCV who were born to HIV/HCV coinfected women, two infants were HCV infected for an HCV transmission rate of 4.2% (95% 0.51-14.25%).
  
  
  CONCLUSIONS
  HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.
authors.affiliation: Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341-3717, USA. djj0@cdc.gov
authors.forename: Denise J
authors.initials: DJ
authors.lastname: Jamieson
authors.forename: Natapakwa
authors.initials: N
authors.lastname: Skunodom
authors.forename: Thanyanan
authors.initials: T
authors.lastname: Chaowanachan
authors.forename: Anuvat
authors.initials: A
authors.lastname: Roongpisuthipong
authors.forename: William A
authors.initials: WA
authors.lastname: Bower
authors.forename: Tawee
authors.initials: T
authors.lastname: Chotpitayasunondh
authors.forename: Wendy
authors.initials: W
authors.lastname: Bhanich Supapol
authors.forename: Wendi L
authors.initials: WL
authors.lastname: Kuhnert
authors.forename: Wimol
authors.initials: W
authors.lastname: Siriwasin
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Wiener
authors.forename: Sanay
authors.initials: S
authors.lastname: Chearskul
authors.forename: Michelle S
authors.initials: MS
authors.lastname: McConnell
authors.forename: Nathan
authors.initials: N
authors.lastname: Shaffer
mesh_terms: D000328:Adult; D015897:Comorbidity; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006526:Hepatitis C / Q000453:epidemiology* / Q000635:transmission; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D016036:Seroepidemiologic Studies; D013785:Thailand; D055815:Young Adult
chemical_list: D018937:Hepatitis C Antibodies