[An analysis of factor influencing the outcome of patients with locally advanced larynx cancer].
OBJECTIVE
Results of treatment of locally advanced larynx cancer T3-4No-4 are unsatisfied. The aim of study is analysis of risk factors.


METHODS
112 patiens with larynx cancer after radical surgical treatment had postoperative radiotherapy (conventional or accelarated).


RESULTS
The 3-year overall survival (OS) was 58%. Margin status and numer of risk factors had impast on OS. The 3-year locoregional control (LRC) was 80%. Number of risk factors, level of hemoglobin, overall tratment time and dose were significantly associated with LRC. Incidence of distant metastases was asssociated with G3 suamous cell carcinoma and index of nalignancy H. Glanz.
Kubrak
Jadwiga
J
Oddział Kliniczny Radioterapii, Pomorskiej Akademii Medycznej, Szczecin.
Jarema
Alina
A
Falco
Michał
M
Rogowska
Danuta
D
Rubik
Agnieszka
A
Torbé
Bogdan
B
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011044:Poland; D011184:Postoperative Period; D011379:Prognosis; D016016:Proportional Hazards Models; D011879:Radiotherapy Dosage; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult