title: [Obesity in CASE-J Study].
abstract: Obesity is closely associated with development of hypertension. Adipose tissue produces molecules of renin-angiotensin system, which contribute to metabolic as well as cardiovascular disorders that develop in obesity. CASE-J Study demonstrated the usefulness of angiotensin receptor blockade in preventing new onset diabetes in obese hypertensive patients.
authors.affiliation: Department of Medicine and Medical Science, Kyoto University Graduate School of Medicine.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Hirata
authors.forename: Kouji
authors.initials: K
authors.lastname: Oba
authors.forename: Kenji
authors.initials: K
authors.lastname: Ueshima
authors.forename: Kazuwa
authors.initials: K
authors.lastname: Nakao
mesh_terms: D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000517:prevention & control*; D009765:Obesity / Q000150:complications*
chemical_list: D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors