Biochemical parameters in chronic fascioliasis.
Serum lipids, liver enzymes and total bile acids were measured in chronic Fasciola (cholestatic and non-cholestatic) patients. Variations in the biochemical parameters between infected and control groups were detected and typified by considerably higher serum triglycerides (TG, P < 0.001), alkaline phosphatase (ALP, P< 0.001) and total bile acids (TBA, P < 0.001) in the infected group. For cholestatic patients, TG, very low density lipoprotein (VLDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gammaglutamyl transferase (GGT) and ALP were statistically higher (P < 0.001 for each comparison) and total cholesterol (TC); low density lipoprotein (LDL) and high density lipoprotein (HDL), were statistically lower than non-cholestatic patients (P = 0.02, < 0.001, < 0.001 respectively). No statistically significant differences were found for the TC, HDL, VLDL, ALT, AST and GGT between non-cholestatic patients and healthy controls.
El-Shazly
Atef M
AM
Department of Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Azab
Manar S
MS
El-Beshbishi
Samar N
SN
Sakr
Tarek I
TI
El-Fayoumy
Khaled N
KN
El-Ghareeb
Aza S
AS
Hafez
Adel O
AO
El Sherbini
Eman T
ET
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001647:Bile Acids and Salts / Q000032:analysis*; D016022:Case-Control Studies; D002779:Cholestasis / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D005211:Fascioliasis / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000201:enzymology*; D012720:Severity of Illness Index; D014280:Triglycerides / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D001647:Bile Acids and Salts; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase