title: Frequency of endometriosis among infertile women and association of clinical signs and symptoms with the laparoscopic staging of endometriosis.
abstract: OBJECTIVE
  The study aimed to determine the frequency of endometriosis in women who underwent diagnostic laparoscopy for evaluation of infertility and the association of clinical, ultrasonographic and laparoscopic findings of endometriosis with the laparoscopic stages of the disease.
  
  
  METHODS
  It was a retrospective study of women presenting to gynaecologic clinics of the Aga Khan University Hospital from January 1999 to December 2005 with primary complaint of primary or secondary infertility and were diagnosed with endometriosis through laparoscopy. Relevant demographic and clinical information was entered and analyzed in SPSS version 14.0.
  
  
  RESULTS
  The frequency of endometriosis in women with primary compliant of infertility was found to be 16.8%. Statistically significant associations was found between staging of the disease and thin built (p=0.007) and restricted uterine mobility on pelvic examination (p=0.035). The patients' ultrasound and laparoscopic examination showed significant association with staging of the disease with the presence of cysts on ultrasound (p-value < 0.0001) and adhesions on laparoscopy (p value <0.00001).
  
  
  CONCLUSIONS
  The variability of the definition and inconsistency in diagnostic methods makes the prevalence of endometriosis difficult to determine and we might underestimate the true burden of the disease. Most of the signs and symptoms of endometriosis do not correlate with the severity (staging) of the disease. Hence, Laparoscopy remains the gold standard for diagnosis as well as staging of endometriosis.
authors.affiliation: Department of Biological and Biomedical Sciences, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Urooj Bakht
authors.initials: UB
authors.lastname: Khawaja
authors.forename: Ameer Ali
authors.initials: AA
authors.lastname: Khawaja
authors.forename: Saqib Ali
authors.initials: SA
authors.lastname: Gowani
authors.forename: Sana
authors.initials: S
authors.lastname: Shoukat
authors.forename: Sana
authors.initials: S
authors.lastname: Ejaz
authors.forename: Farzana Nawaz
authors.initials: FN
authors.lastname: Ali
authors.forename: Javaid
authors.initials: J
authors.lastname: Rizvi
authors.forename: Fauzia Haq
authors.initials: FH
authors.lastname: Nawaz
mesh_terms: D000293:Adolescent; D000328:Adult; D018450:Disease Progression; D004715:Endometriosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology*; D010535:Laparoscopy; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D014463:Ultrasonography; D055815:Young Adult