title: Validation of the Italian version of the Neuropathic Pain Symptom Inventory in peripheral nervous system diseases.
abstract: The aim of this study was to validate the Italian version of the Neuropathic Pain Symptom Inventory (NPSI) in patients with neuropathic pain due to peripheral nerve diseases, and also to evaluate the validity of a new NPSI score: a frequency weighted NPSI score (NPSI-FW). First, the original version of the NPSI was translated into Italian. Then the validity and reliability of the Italian NPSI (I-NPSI) were tested in 392 Italian patients consecutively referred to 16 Italian outpatient services for peripheral nerve diseases, by correlating the I-NPSI scores with other pain scales. The repeatability and responsiveness were assessed. A significant correlation between the I-NPSI scores and all the other pain measures was seen. Reproducibility and responsiveness were good. Our study shows the validity of the I-NPSI and demonstrates its reliability for assessing neuropathic pain in patients with peripheral nerve diseases. The I-NPSI scores represent reliable measurements to assess neuropathic symptoms and effectiveness of treatment on them.
authors.affiliation: Department of Neurosciences, Institute of Neurology, UCSC University, Largo F. Vito 1, 00168, Rome, Italy. lpadua@rm.unicatt.it
authors.forename: Luca
authors.initials: L
authors.lastname: Padua
authors.forename: Chiara
authors.initials: C
authors.lastname: Briani
authors.forename: Stefano
authors.initials: S
authors.lastname: Jann
authors.forename: Eduardo
authors.initials: E
authors.lastname: Nobile-Orazio
authors.forename: Costanza
authors.initials: C
authors.lastname: Pazzaglia
authors.forename: Alberto
authors.initials: A
authors.lastname: Morini
authors.forename: Mauro
authors.initials: M
authors.lastname: Mondelli
authors.forename: Palma
authors.initials: P
authors.lastname: Ciaramitaro
authors.forename: Guido
authors.initials: G
authors.lastname: Cavaletti
authors.forename: Dario
authors.initials: D
authors.lastname: Cocito
authors.forename: Raffaella
authors.initials: R
authors.lastname: Fazio
authors.forename: Lucio
authors.initials: L
authors.lastname: Santoro
authors.forename: Francesca
authors.initials: F
authors.lastname: Galeotti
authors.forename: Marinella
authors.initials: M
authors.lastname: Carpo
authors.forename: Rosaria
authors.initials: R
authors.lastname: Plasmati
authors.forename: Luana
authors.initials: L
authors.lastname: Benedetti
authors.forename: Angelo
authors.initials: A
authors.lastname: Schenone
authors.forename: Paolo
authors.initials: P
authors.lastname: Marchettini
authors.forename: Giorgio
authors.initials: G
authors.lastname: Cruccu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005602:France; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D010147:Pain Measurement / Q000379:methods*; D010525:Peripheral Nerves / Q000187:drug effects / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013997:Time Factors; D014175:Translating; D016896:Treatment Outcome; D055815:Young Adult