A four-color colloidal multiplexing nanoparticle system.
Any labeling with multicolor markers can be affected by the autofluorescence of biological tissue due to the UV or blue light excitation sources, or the results are affected by fluorescence resonance energy transfer. In this work, we present novel IR-to-vis upconverting nanoparticles of different rare earth metal dopants. With a single excitation source of 980 nm, four different colors of nanocrystals can be spectrally separated under multiplexing conditions. The particles were phase transferred into polar solvents by means of silica encapsulation and were characterized by transmission electron microscopy, X-ray diffraction, and photoluminescence spectroscopy.
Ehlert
Oliver
O
Freiburg Materials Research Center, University of Freiburg, Germany.
Thomann
Ralf
R
Darbandi
Masih
M
Nann
Thomas
T
D003102:Colloids; D003116:Color; D028581:Lanthanoid Series Elements / Q000737:chemistry; D049449:Luminescence; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D003102:Colloids; D028581:Lanthanoid Series Elements