title: Outcome after multidisciplinary CO2 laser laparoscopic excision of deep infiltrating colorectal endometriosis.
abstract: The aim of this retrospective cohort study was to evaluate clinical outcome after multidisciplinary laparoscopic excision of deep endometriosis. Patients (n = 56) were asked to complete questionnaires regarding quality of life (QOL), pain, fertility and sexuality to compare their status before and after surgery, and their medical files were analysed. Statistical analysis was performed with life table analysis, paired Wilcoxon and McNemar tests. Gynaecological pain, QOL and sexual activity improved significantly (P < 0.001; P < 0.0001 to P = 0.008 and P < 0.0001 to P = 0.0003 respectively) during a median follow-up 29 months after surgery. Post operative complications occurred in 11% but were directly related to surgery in only 5%. The cumulative recurrence rate of endometriosis was 2 and 7% at 1 and 4 years after surgery respectively. Cumulative pregnancy rate was 31 and 70% at 1 and 4 years after surgery respectively. In conclusion, multidisciplinary CO(2) laser laparoscopic excision of deep endometriosis with colorectal extension improves pain, QOL and sexuality with high fertility and low complication and recurrence rates.
authors.affiliation: Leuven University Fertility Centre, Department of Obstetrics and Gynecology, University Hospital Leuven, Belgium.
authors.forename: Christel
authors.initials: C
authors.lastname: Meuleman
authors.forename: André
authors.initials: A
authors.lastname: D'Hoore
authors.forename: Ben
authors.initials: B
authors.lastname: Van Cleynenbreugel
authors.forename: Nele
authors.initials: N
authors.lastname: Beks
authors.forename: Thomas
authors.initials: T
authors.lastname: D'Hooghe
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003108:Colonic Diseases / Q000601:surgery*; D003107:Colorectal Surgery / Q000379:methods*; D004715:Endometriosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology; D033183:Interdisciplinary Communication; D010535:Laparoscopy / Q000379:methods*; D054020:Lasers, Gas / Q000627:therapeutic use*; D010146:Pain / Q000453:epidemiology / Q000209:etiology; D011183:Postoperative Complications / Q000453:epidemiology; D012002:Rectal Diseases / Q000601:surgery*; D012189:Retrospective Studies; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology / Q000209:etiology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult