title: Effects of intramuscular acepromazine and diazepam on tear production in rabbits.
abstract: Sixteen New Zealand white rabbits were divided randomly into two groups of eight. Schirmer II tear tests were performed on all 16 and then eight received an intramuscular dose of 1 mg/kg acepromazine and the other eight received an intramuscular dose of 1 mg/kg diazepam. The Schirmer tests were repeated after 15 and 25 minutes. There was a significant reduction in tear production by the rabbits treated with acepromazine, but no significant change in tear production by the rabbits treated with diazepam.
authors.affiliation: Department of Clinical Studies, Islamic Azad University, Karaj, Iran. selkghaffari@gmail.com
authors.forename: M Selk
authors.initials: MS
authors.lastname: Ghaffari
authors.forename: A P
authors.initials: AP
authors.lastname: Moghaddassi
authors.forename: S
authors.initials: S
authors.lastname: Bokaie
mesh_terms: D000075:Acepromazine / Q000494:pharmacology*; D000818:Animals; D003975:Diazepam / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D007273:Injections, Intramuscular / Q000662:veterinary; D009125:Muscle Relaxants, Central / Q000494:pharmacology*; D011817:Rabbits / Q000502:physiology*; D011897:Random Allocation; D013666:Tears / Q000187:drug effects* / Q000378:metabolism
chemical_list: D018492:Dopamine Antagonists; D009125:Muscle Relaxants, Central; D000075:Acepromazine; D003975:Diazepam