Serum aluminum level correlates with arterial stiffness in haemodialysis patients.
BACKGROUND
In addition to pulse wave velocity (PWV), serum aluminum level is predictive of mortality in haemodialysis (HD) patients. This cross-sectional study evaluated the correlations between serum aluminum and brachial-ankle PWV (baPWV).


METHODS
One hundred twenty-seven HD patients (average age 58.46 +/- 9.95 years) were enrolled. Medical data were obtained via chart reviews and hospital database. Associations between biomarker levels and baPWV were analysed by multiple linear regression.


RESULTS
Serum aluminum, high sensitivity C-reactive protein (hsCRP), age, pulse pressure (PP), mean arterial pressure (MAP) and diabetes mellitus (DM) are important correlates of baPWV.


CONCLUSIONS
Further, hsCRP, PP, age and DM are positively related to arterial stiffness in HD patients.
Weng
C-H
CH
Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan, China.
Huang
W-H
WH
Yu
C-C
CC
Chang
C-T
CT
Yang
C-W
CW
D000368:Aged; D000535:Aluminum / Q000097:blood*; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000502:physiology; D001916:Brachial Artery; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D006435:Renal Dialysis; D014655:Vascular Resistance / Q000502:physiology*
D002097:C-Reactive Protein; D000535:Aluminum