title: Modelling the resource implications and budget impact of managing cow milk allergy in Australia.
abstract: OBJECTIVE
  To estimate the resource implications and budget impact of current clinical practice for managing cow milk allergy (CMA) in Australia, from the perspective of the publicly funded healthcare system.
  
  
  METHODS
  A decision model was constructed using published clinical outcomes and clinician-derived resource utilisation estimates. The model was used to estimate the expected 6-monthly levels of healthcare resource use and corresponding costs attributable to managing 6150 new CMA sufferers following referral to a specialist.
  
  
  RESULTS
  The expected 6-monthly costs of managing 6150 newly-diagnosed infants with CMA following referral to a specialist was an estimated (Australian dollars, AU$) AU$6.5 million at 2006/07 prices. Clinical nutrition preparations were found to be the primary cost driver accounting for 62% of the total 6-monthly cost and clinician visits were the secondary cost driver accounting for up to a further 28% of the total 6-monthly cost. Sensitivity analysis showed there would be fewer visits to hospital-based paediatric gastroenterologists and paediatric immunologists/allergists if all newly-diagnosed patients were prescribed an amino acid formula (AAF) following referral to a specialist, instead of being managed according to current practice.
  
  
  CONCLUSIONS
  CMA imposes a substantial burden on the publicly funded healthcare system in Australia. However, using an AAF as the initial treatment for CMA can potentially release limited hospital resources for alternative use within the paediatric healthcare system.
authors.affiliation: Catalyst Health Economics Consultants, Northwood, Middlesex, UK. julian.guest@catalyst-health.co.uk
authors.forename: J F
authors.initials: JF
authors.lastname: Guest
authors.forename: E
authors.initials: E
authors.lastname: Nagy
mesh_terms: D001315:Australia / Q000453:epidemiology; D002017:Budgets; D003663:Decision Trees; D015276:Health Care Rationing; D006801:Humans; D007223:Infant; D016269:Milk Hypersensitivity / Q000191:economics / Q000453:epidemiology / Q000628:therapy*; D010818:Practice Patterns, Physicians'; D012680:Sensitivity and Specificity