title: [Influence of thermolabile lethal toxin of Yersinia pseudotuberculosis on development of sea urchin embryos and biosynthesis of DNA and RNA in embryonic cells].
abstract: Influence of thermolabile lethal toxin of Y. pseudotuberculosis on the development of embryos of sea urchin (Strongylocentrotus intermedius) and on biosynthesis of nucleic acids in embryonic cells was studied. Thermolabile lethal toxin affected metabolic processes of cells by inhibiting DNA and RNA synthesis. It had damaging action on developing embryos of sea urchin causing morphological changes and, as a consequence, death of embryos.
authors.forename: N F
authors.initials: NF
authors.lastname: Timchenko
authors.forename: N A
authors.initials: NA
authors.lastname: Terent'eva
authors.forename: V K
authors.initials: VK
authors.lastname: Pokrovskiĭ
authors.forename: L L
authors.initials: LL
authors.lastname: Terent'ev
authors.forename: E P
authors.initials: EP
authors.lastname: Nedashkovskaia
authors.forename: V A
authors.initials: VA
authors.lastname: Rasskazov
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000302:isolation & purification / Q000633:toxicity*; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects*; D004625:Embryo, Nonmammalian / Q000187:drug effects* / Q000378:metabolism; D006358:Hot Temperature; D012313:RNA / Q000096:biosynthesis / Q000187:drug effects*; D047269:Strongylocentrotus / Q000187:drug effects* / Q000196:embryology; D015011:Yersinia pseudotuberculosis
chemical_list: D001427:Bacterial Toxins; D012313:RNA; D004247:DNA