title: [Isolated mandibular B-cell lymphoma revealed by inferior alveolar nerve anesthesia].
abstract: BACKGROUND
  Mandibular lymphomas are rare and most often revealed by painless swelling. The authors report the case of a mandibular lymphoma revealed by an isolated lesion of the inferior alveolar nerve evolving for eight months.
  
  
  METHODS
  A 41-year-old male patient was followed for left mandibular pain, with progressive hypoesthesia of the left inferior alveolar nerve. The radiological assessments remained normal during eight months. Then a vestibular tumor developed in front of tooth 34. The biopsy revealed a B-cell lymphoma. No other localization was found. The patient was in complete remission two years after polychemotherapy.
  
  
  CONCLUSIONS
  Our observation is unusual in its clinical presentation. Mandibular lymphomas most often present as a painless swelling, sometimes ulcerated in the mouth. They are very rarely diagnosed after an isolated hypoesthesia of V3. Lymphomas are the second most frequent head and neck lymphomas after epidermoid carcinomas, but the frequency seems to be increasing. In almost all the cases, they present as B-cell tumours of the DLBCL subtype in the WHO classification. Mandibular localizations account for only 0.6% of the cases. They are often misdiagnosed as a dental problem. The complete remission rate after chemotherapy ranges from 60 to 80% at one year. Nevertheless, the prognosis remains bad with a survival rate of only 50% at five years.
authors.affiliation: Service de chirurgie maxillofaciale et stomatologie, chirurgie plastique, esthétique et réparatrice, chirurgie de la main, CHU de Dijon, 3, rue du Faubourg-Raines, BP 1519, 21033 Dijon, France. olivier.trost@chu-dijon.fr
authors.forename: O
authors.initials: O
authors.lastname: Trost
authors.forename: C
authors.initials: C
authors.lastname: Charon-Barra
authors.forename: P
authors.initials: P
authors.lastname: Soichot
authors.forename: G
authors.initials: G
authors.lastname: Moreau
authors.forename: P
authors.initials: P
authors.lastname: Trouilloud
authors.forename: G
authors.initials: G
authors.lastname: Malka
mesh_terms: D000328:Adult; D003389:Cranial Nerve Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D004568:Electrodiagnosis; D005157:Facial Pain / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D006987:Hypesthesia / Q000175:diagnosis*; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis*; D008340:Mandibular Nerve / Q000503:physiopathology*