Spatiotemporal mapping of the motility of the isolated chicken caecum.
We studied the caecal contractile activity of the chicken (Gallus gallus) using single caeca that had been cannulated at their proximal and distal ends, and in paired caeca, maintained in situ on excised segments of gut that were cannulated at the colonic and small intestinal ends. Longitudinal and circular contractile patterns were characterised using high-definition spatiotemporal mapping. Low amplitude longitudinal contraction waves of frequency 14.1 cycles/min occurred in the absence of major contractile events. These were termed fast phasic and appeared to be mediated by slow waves. The nature of major spontaneous contractions occurring in the single caecum varied with the level of caecal distension. Type A contractions occurred when the caecum was not distended, originated from variable sites and propagated in both directions. Type B or C contractile events occurred when the caecum was moderately or fully distended, originated from a predominantly distal site and propagated proximally. On diameter maps, each type B event comprised a succession of contractions which had similar propagation speeds, frequency and direction to fast phasic contractions. Type C events were comprised of a succession of higher amplitude contractions with no appreciable propagation. Perfusion of saline via the colon resulted in fluid entering both caeca and the onset of aborad contractions in their proximal canals. Saline was also seen to flow between caeca during contractile events however no saline was seen to enter the small intestine as has been postulated by other workers.
Janssen
Patrick W M
PW
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North, New Zealand. p.janssen@massey.ac.nz
Lentle
Roger G
RG
Hulls
Corrin
C
Ravindran
Velmurugu
V
Amerah
Ahmed M
AM
D000818:Animals; D002432:Cecum / Q000502:physiology*; D002645:Chickens; D005685:Galactans; D005769:Gastrointestinal Motility / Q000187:drug effects / Q000502:physiology*; D008012:Lidocaine / Q000494:pharmacology; D008351:Mannans; D009119:Muscle Contraction / Q000502:physiology; D010477:Perfusion; D053149:Plant Gums; D014783:Viscosity
D005685:Galactans; D008351:Mannans; D053149:Plant Gums; D008012:Lidocaine; C007894:guar gum