Fatal Ophiostoma piceae infection in a patient with acute lymphoblastic leukaemia.
We report to our knowledge the first case of human infection with Ophiostoma piceae. This Sporothrix schenckii-related fungus caused disseminated infection involving the lung and the brain in a patient with lymphoblastic lymphoma. The case emphasizes the significance of molecular techniques for identification of rare fungi in the clinical microbiology laboratory.
Bommer
Martin
M
Department of Internal Medicine III, University Hospital of Ulm, Germany.
Hütter
Marie-Luise
ML
Department of Internal Medicine III, University Hospital of Ulm, Germany.
Stilgenbauer
Stephan
S
Department of Internal Medicine III, University Hospital of Ulm, Germany.
de Hoog
G Sybren
GS
Centraalbureau voor Schimmelcultures (CBS), Utrecht, The Netherlands.
de Beer
Z Wilhelm
ZW
Department of Microbiology and Plant Pathology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, South Africa.
Wellinghausen
Nele
N
Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Germany.
D000328:Adult; D001483:Base Sequence; D001706:Biopsy; D001921:Brain / Q000382:microbiology / Q000601:surgery; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008969:Molecular Sequence Data; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D055156:Ophiostoma / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed