title: The influenza virus enigma.
abstract: Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.
authors.affiliation: Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105-2678, USA.
authors.forename: Rachelle
authors.initials: R
authors.lastname: Salomon
authors.forename: Robert G
authors.initials: RG
authors.lastname: Webster
mesh_terms: D000818:Animals; D001717:Birds; D004197:Disease Reservoirs; D024882:Drug Resistance, Viral; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects / Q000502:physiology; D053122:Influenza A Virus, H3N2 Subtype / Q000502:physiology; D053124:Influenza A Virus, H5N1 Subtype / Q000502:physiology; D009980:Influenza A virus / Q000472:pathogenicity / Q000502:physiology*; D007252:Influenza Vaccines / Q000276:immunology; D005585:Influenza in Birds / Q000821:virology; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control / Q000635:transmission / Q000821:virology*; D009976:Orthomyxoviridae Infections / Q000821:virology; D011159:Population Surveillance
chemical_list: D007252:Influenza Vaccines