Fluorescent amino acids: advances in protein-extrinsic fluorophores.
Fluorescent labeling is today of paramount importance to biological studies and numerous chemical dyes are used extensively to label biological specimens. This perspective highlights interesting aspects of fluorescent labeling by fluorescent peptides and small organic fluorophores that can be incorporated into proteins by genetic fusion to produce a fluorescent label. While many fluorescence applications rely on the use of intrinsic fluorophores, the development of new extrinsic fluorophores remains an essential element for the design of new fluorescent probes.
Katritzky
Alan Roy
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. katritzky@chem.ufl.edu
Narindoshvili
Tamari
T
D000596:Amino Acids; D005456:Fluorescent Dyes / Q000737:chemistry*; D015336:Molecular Probe Techniques; D011506:Proteins
D000596:Amino Acids; D005456:Fluorescent Dyes; D011506:Proteins