title: The structural dynamics of macromolecular processes.
abstract: Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.
authors.affiliation: Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158-2330, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Russel
authors.forename: Keren
authors.initials: K
authors.lastname: Lasker
authors.forename: Jeremy
authors.initials: J
authors.lastname: Phillips
authors.forename: Dina
authors.initials: D
authors.lastname: Schneidman-Duhovny
authors.forename: Javier A
authors.initials: JA
authors.lastname: Velázquez-Muriel
authors.forename: Andrej
authors.initials: A
authors.lastname: Sali
mesh_terms: D002468:Cell Physiological Phenomena; D003198:Computer Simulation; D046911:Macromolecular Substances / Q000378:metabolism*; D008954:Models, Biological
chemical_list: D046911:Macromolecular Substances