title: Port-site metastasis of extrahepatic bile duct carcinoma after laparoscopic cholecystectomy without evidence of a primary tumour.
abstract: A 75-year-old man suffering from symptomatic cholelithiasis underwent laparoscopic cholecystectomy using the four-port technique. No malignancy was observed in the resected gall-bladder and the patient exhibited a good postoperative course. Eleven months postoperatively he presented with two subcutaneous tumours: one at the port-site on the right anterior axillary line (at the position of the vacuum drain) and the other at the subumbilical port-site. The patient underwent an incisional biopsy, which revealed metastatic adenocarcinomas of the primary extrahepatic duct, with no evidence of a primary tumour or other distant metastasis. The patient underwent wide excision of the subcutaneous tumours. Six months later he again presented with subcutaneous tumours at the same positions. Magnetic resonance imaging of the abdomen revealed only the subcutaneous tumours. The patient again underwent wide excision of the subcutaneous tumours, followed by radiotherapy. At a 21-month follow-up the patient was symptom-free. Magnetic resonance imaging of the abdomen and magnetic resonance cholangiopancreatography results were normal, and there was no evidence of other metastasis. Four months later the patient died from metastatic disease of the abdomen.
authors.affiliation: Second Department of Surgery, Democritus University of Thrace, Alexandroupolis, Greece. tsihrin@otenet.gr
authors.forename: A
authors.initials: A
authors.lastname: Polychronidis
authors.forename: A K
authors.initials: AK
authors.lastname: Tsaroucha
authors.forename: S
authors.initials: S
authors.lastname: Perente
authors.forename: A
authors.initials: A
authors.lastname: Giatromanolaki
authors.forename: M
authors.initials: M
authors.lastname: Koukourakis
authors.forename: C
authors.initials: C
authors.lastname: Simopoulos
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D001650:Bile Duct Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D017734:Bile Ducts, Extrahepatic; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery; D017809:Fatal Outcome; D005704:Gallbladder / Q000293:injuries; D006801:Humans; D007431:Intraoperative Complications; D008279:Magnetic Resonance Imaging; D008297:Male; D009366:Neoplasm Seeding; D012421:Rupture