SUPRAPhos ligands for the regioselective rhodium catalyzed hydroformylation of styrene forming the linear aldehyde.
We report SUPRAphos-based rhodium catalysts that are unusually regioselective in the hydroformylation of styrene at low temperatures (40 degrees C) producing mainly the linear aldehyde (72%). This ligand-specific phenomenon is observed for two rhodium catalysts with heterobidentate phosphine-phosphoramidite ligands. We propose that the high selectivity for the linear product is caused by enhanced beta-hydride elimination, due to specific substrate-ligand interactions, most likely pi-pi interactions.
Goudriaan
P Elsbeth
PE
Homogeneous and Supramolecular Chemistry, Van't Hoff Institute for Molecular Sciences, Nieuwe Achtergracht 166, 1018 WV, Amsterdam, The Netherlands.
Kuil
Mark
M
Jiang
Xiao-Bin
XB
van Leeuwen
Piet W N M
PW
Reek
Joost N H
JN