Ascaridole and related peroxides from the genus Chenopodium.
OBJECTIVE
Detection of monoterpenoid ascaridole and other terpenoids in the genus Chenopodium from the East Mediterranean.


METHODS
Distribution of ascaridole in leaves of 13 species medicinal plant belonging to the genus Chenopodium was examined with the help of the GC MS method.


RESULTS
cis Ascaridole was found as a major peroxy monoterpenoid (up to 46.9 %) in the oil. Three minor isomers: cis isoascaridole (1.1 6.4 %), trans ascaridole (1 2 %), and trans isoascaridole (1 2 %) were also detected. The biological activities and biosynthesis of ascaridole are further discussed.


CONCLUSIONS
The results on Ascaridol and the major volatiles and semi volatiles of wild species belonging to the genus Chenopodium provide important information on biologically active monoterpenoid compounds and volatile metabolites biosynthesized in wild medicinal plants growing in the East Mediterranean.
Dembitsky
Valery
V
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Hebrew University, Jerusalem, Israel.
Shkrob
Ilya
I
Hanus
Lumir Ondrej
LO
D027462:Chenopodium / Q000737:chemistry*; D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes / Q000032:analysis*; D010545:Peroxides / Q000032:analysis*; D010946:Plants, Medicinal / Q000737:chemistry*; D013729:Terpenes / Q000032:analysis
D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes; D010545:Peroxides; D013729:Terpenes; C043372:ascaridole