The effect of plant sterols or stanols on lipid parameters in patients with type 2 diabetes: a meta-analysis.
We performed a meta-analysis of five randomized, placebo-controlled trials to characterize the impact of plant sterols/stanols on plasma lipids in patients with type 2 diabetes. Upon meta-analysis, plant sterols/stanols significantly reduced total and LDL cholesterol, with a trend towards improvement in HDL. No beneficial effect on triglycerides was apparent.
Baker
William L
WL
The Evidence-Based Practice Center, Hartford Hospital, Hartford, CT 06102-5037, United States.
Baker
Erica L
EL
Coleman
Craig I
CI
D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood* / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D008055:Lipids / Q000097:blood*; D010840:Phytosterols / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012855:Sitosterols / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D008055:Lipids; D010840:Phytosterols; D012855:Sitosterols; D014280:Triglycerides; D002784:Cholesterol