title: ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.
abstract: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.
authors.affiliation: INSERM, AVENIR Team, Integrative Cancer Immunology, U872, Paris, France.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Bindea
authors.forename: Bernhard
authors.initials: B
authors.lastname: Mlecnik
authors.forename: Hubert
authors.initials: H
authors.lastname: Hackl
authors.forename: Pornpimol
authors.initials: P
authors.lastname: Charoentong
authors.forename: Marie
authors.initials: M
authors.lastname: Tosolini
authors.forename: Amos
authors.initials: A
authors.lastname: Kirilovsky
authors.forename: Wolf-Herman
authors.initials: WH
authors.lastname: Fridman
authors.forename: Franck
authors.initials: F
authors.lastname: Pagès
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Trajanoski
authors.forename: Jérôme
authors.initials: J
authors.lastname: Galon
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D053263:Gene Regulatory Networks; D008954:Models, Biological; D005810:Multigene Family; D012984:Software