title: Biodiversity of the chemical constituents in the epiphytic lichenized ascomycete Ramalina lacera grown on difference substrates Crataegus sinaicus, Pinus halepensis, and Quercus calliprinos.
abstract: OBJECTIVE
  The identification and evaluation of lichen metabolite production by the epiphytic lichenized ascomycete Ramalina lacera collected from different substrates: Crataegus sinaicus, Pinus halepensis, and Quercus calliprinos.
  
  
  METHODS
  Chemical constituents were characterized by GC MS, HPLC, HR TLC, and other chemical methods.
  
  
  RESULTS
  The most abundant fatty acids were alpha-linolenic acid, oleic acid, and palmitic acid but a considerable variability of the ester composition from one to another was found. A comparison of neutral lipids, glycolipids, polar lipids and fatty acid composition of the tree growing lichen Ramalina lacera was done. Diacylglyceryl N,N,N trimethylhomoserine, diaclyglycerylhydroxymethyl N,N,N trimethyl beta alanine, phosphatidylcholine, and phosphatidylinositol were found as major components among polar lipids. Diffractaic, lecanoric, norstictic, protocetric, and usnic acids were isolated as major aromatic compounds in all samples of R. lacera.
  
  
  CONCLUSIONS
  We evaluated a diversity of fatty acids, lipids, and aromatic compounds produced by the samples of Ramalina lacera growing on different tree substrates, Crataegus sinaicus, Pinus halepensis and Quercus calliprinos.
authors.affiliation: Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Hebrew University, Jerusalem, Israel. lumir@cc.huji.ac.il
authors.forename: Lumir Ondrej
authors.initials: LO
authors.lastname: Hanus
authors.forename: Marina
authors.initials: M
authors.lastname: Temina
authors.forename: Valery
authors.initials: V
authors.lastname: Dembitsky
mesh_terms: D001203:Ascomycota / Q000737:chemistry* / Q000254:growth & development; D027825:Crataegus; D005227:Fatty Acids / Q000032:analysis; D008011:Lichens / Q000737:chemistry / Q000254:growth & development; D008055:Lipids / Q000032:analysis; D029963:Quercus; D013559:Symbiosis
chemical_list: D005227:Fatty Acids; D008055:Lipids