title: A hierarchical model for evolution of 23S ribosomal RNA.
abstract: The emergence of the ribosome constituted a pivotal step in the evolution of life. This event happened nearly four billion years ago, and any traces of early stages of ribosome evolution are generally thought to have completely eroded away. Surprisingly, a detailed analysis of the structure of the modern ribosome reveals a concerted and modular scheme of its early evolution.
authors.affiliation: Département de Biochimie, Université de Montréal, Montréal, H3C 3J7 (Québec), Canada.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Bokov
authors.forename: Sergey V
authors.initials: SV
authors.lastname: Steinberg
mesh_terms: D004926:Escherichia coli / Q000235:genetics*; D019143:Evolution, Molecular; D008954:Models, Biological; D009690:Nucleic Acid Conformation; D000069497:Origin of Life; D012338:RNA, Ribosomal, 23S / Q000737:chemistry* / Q000235:genetics
chemical_list: D012338:RNA, Ribosomal, 23S