Aneuploidy of stem cells isolated from human adipose tissue.
The incidence of autosomes 6 and 8 aneuploidy in stem cell cultures derived from adipose tissue was evaluated at different stages of culturing. Monosomy was more incident than trisomy during the early passages. Distribution of cultures by the incidence of aneuploidy in different chromosomes was virtually the same. Clones with chromosome 6 monosomy were detected in two cultures during late passages.
Bochkov
N P
NP
Medical Genetic Research Center, Russian Academy of Medical Sciences, Russia.
Nikitina
V A
VA
Buyanovskaya
O A
OA
Voronina
E S
ES
Goldstein
D V
DV
Kuleshov
N P
NP
Rzhaninova
A A
AA
Chaushev
I N
IN
D000273:Adipose Tissue / Q000166:cytology*; D000782:Aneuploidy; D002478:Cells, Cultured; D002896:Chromosomes, Human, Pair 6; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D013234:Stem Cells / Q000648:ultrastructure*