Analysis of factors that induce cysteine bonding state.
Regarding the fact that the protein structure is principally encoded in its sequence, investigating the bonding state of cysteine has gained a great deal of attention due to its significance in the formation of protein structure. Due to lack of evident influence of free cysteines on the protein structure, it may be expected that only half-cystines convey encoded information. The results obtained from the analysis of amino acid distribution in proximity of both states of cysteines explicitly indicated that perquisite information for inducing cysteine bonding state is present even in the flanking amino acid sequences of free cysteines.
Hoseini
Somayyeh
S
Department of Biophysics, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran. [corrected]
Jahandideh
Mina
M
Hoseini
Afsaneh
A
Yazdi
Ali Salehzadeh
AS
Karami
Zahra
Z
Abdolmaleki
Parviz
P
Rezaei
Mohammad Ali
MA
Jahandideh
Samad
S
Asadabadi
Ebrahim Barzegari
EB
D000596:Amino Acids / Q000737:chemistry; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D003545:Cysteine / Q000737:chemistry*; D030562:Databases, Protein; D004220:Disulfides; D008968:Molecular Conformation; D015394:Molecular Structure; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry; D020539:Sequence Analysis, Protein; D012984:Software
D000596:Amino Acids; D004220:Disulfides; D011506:Proteins; D003545:Cysteine