title: Phytochemical and acute toxicity study on Tinospora tomentosa Miers.
abstract: The stems of Tinospora tomentosa Miers. are used in Indian system of medicine. The present study deals with the preliminary qualitative phytochemical investigation and acute toxicity study on various extracts of the plant. The acute toxicity was studied in mice and rats in terms of 24 h LD50 of the methanol and aqueous extracts. These extracts were found to be non-toxic orally in doses up to 3.5 g/kg in both mice and rats.
authors.affiliation: Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, Jadavpur University, Kolkata-700032, India. ddjupt@yahoo.co.in
authors.forename: Debabrata
authors.initials: D
authors.lastname: Devbhuti
authors.forename: Jayanta Kumar
authors.initials: JK
authors.lastname: Gupta
authors.forename: Pritesh
authors.initials: P
authors.lastname: Devbhuti
authors.forename: Anindya
authors.initials: A
authors.lastname: Bose
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D007928:Lethal Dose 50; D008297:Male; D008515:Medicine, Ayurvedic; D051379:Mice; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity*; D018547:Plant Stems; D051381:Rats; D031610:Tinospora / Q000737:chemistry*; D023382:Toxicity Tests, Acute
chemical_list: D010936:Plant Extracts