Synthesis of thiol-linked neoglycopolymers and thermo-responsive glycomicelles as potential drug carrier.
Homopolymer and block copolymer bearing carbohydrate side chain functionality were obtained by grafting glucothiose onto alkene functional scaffolds via a thiol-ene click reaction and the resulting copolymer was used to form thermo-responsive micelles as a potential drug carrier.
Chen
Gaojian
G
Centre for Advanced Macromolecular Design (CAMD), School of Chemical Science and Engineering, The University of New South Wales, Sydney, NSW 2052, Australia.
Amajjahe
Sadik
S
Stenzel
Martina H
MH
D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry*; D008823:Micelles; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013696:Temperature
D004337:Drug Carriers; D008823:Micelles; D011108:Polymers; D013438:Sulfhydryl Compounds; D005947:Glucose