Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction.
Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We investigated the effects of tissue-cultured mountain ginseng extract (TMGE) on male patients with erectile dysfunction (ED). A double-blind, placebo-controlled study was conducted with 143 patients experiencing ED. Over the course of 8 weeks, one group took 1 000 mg of TMGE twice a day, and the other group took 1,000 mg of placebo twice a day. The effects of the TMGE and the placebo were analyzed using the Korean version of the International Index of Erectile Function (IIEF) questionnaire. A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P<0.05), whereas no significant improvement was observed in the placebo group (P>0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P<0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients.
Kim
Tae-Hwan
TH
Department of Urology, School of Medicine, Kyung Hee University, Seoul 134-727, Korea.
Jeon
Seung Hyun
SH
Hahn
Eun-Joo
EJ
Paek
Kee-Yoeup
KY
Park
Jong Kwan
JK
Youn
Nae Young
NY
Lee
Hyung-Lae
HL
D000328:Adult; D000368:Aged; D019149:Bioreactors; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005894:Panax / Q000254:growth & development*; D010352:Patient Dropouts; D017060:Patient Satisfaction; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000627:therapeutic use*; D018517:Plant Roots / Q000166:cytology / Q000254:growth & development; D016896:Treatment Outcome
D010936:Plant Extracts