[Hairy cell leukemia in young patients].
OBJECTIVE
To characterize clinical symptoms, course, immediate and long-term treatment results in young patients with hair cell leukemia (HCL).


METHODS
The data on 41 HCL patients were analysed. The diagnosis was made by standard diagnostic protocol for HCL detection.


RESULTS
The analysis of the age of 160 HCL patients studied demonstrated high (26%) incidence of HCL at young age. Young patients with HCL had special clinical manifestations and specific long-term outcomes of treatment with standard schemes.


CONCLUSIONS
Differences in occurrence of recurrences after standard therapy make it necessary to consider young HCL patients as a separate group who need adjuvant treatment to prolong remission.
Al'-Radi
L S
LS
Samoĭlova
R S
RS
Tikhonova
L Iu
LIu
Diagileva
O A
OA
Naumova
I N
IN
Kaplanskaia
I B
IB
Varlamova
E Iu
EIu
D000328:Adult; D000367:Age Factors; D015703:Antigens, CD / Q000276:immunology; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D017338:Cladribine / Q000008:administration & dosage / Q000627:therapeutic use; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007370:Interferon Type I / Q000008:administration & dosage / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology / Q000628:therapy*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D011994:Recombinant Proteins; D012737:Sex Factors; D013156:Splenectomy
D015703:Antigens, CD; D000970:Antineoplastic Agents; D007370:Interferon Type I; D011994:Recombinant Proteins; D017338:Cladribine