title: Beneficial effects of individualized physical activity on prescription on body composition and cardiometabolic risk factors: results from a randomized controlled trial.
abstract: BACKGROUND
  Insufficient physical activity (PA), overweight and abdominal obesity are increasing global public health problems.
  
  
  METHODS
  Randomized controlled 6-month intervention study.
  
  
  METHODS
  One hundred and one 68-year-old individuals (57% female) with low PA, overweight (BMI 25-40 kg/m) and abdominal obesity (waist circumference >88 cm in women and >102 cm in men), were randomized to PA on prescription (PAP) or a minimal intervention. PA measured by several methods, anthropometric parameters, body composition and cardiometabolic risk factors were measured at baseline and after intervention.
  
  
  RESULTS
  Favourable changes in anthropometrics, body composition, S-glucose, glycosolated haemoglobin (HbA1c), blood lipids and apolipoproteins were seen in the PAP group. In the control group, however, some positive changes were also noted. Bodyweight, neck circumference, fat mass, S-cholesterol and HbA1c decreased significantly more in the PAP group.
  
  
  CONCLUSIONS
  Individualized PAP improves body composition and cardiometabolic risk factors in sedentary older overweight individuals. PAP might be useful in clinical practice to counteract the epidemic of sedentary lifestyle and concomitant cardiometabolic disorders.
authors.affiliation: Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden. lena.kallings@ki.se
authors.forename: Lena V
authors.initials: LV
authors.lastname: Kallings
authors.forename: Justo
authors.initials: J
authors.lastname: Sierra Johnson
authors.forename: Rachel M
authors.initials: RM
authors.lastname: Fisher
authors.forename: Ulf de
authors.initials: Ud
authors.lastname: Faire
authors.forename: Agneta
authors.initials: A
authors.lastname: Ståhle
authors.forename: Erik
authors.initials: E
authors.lastname: Hemmingsson
authors.forename: Mai-Lis
authors.initials: ML
authors.lastname: Hellénius
mesh_terms: D000368:Aged; D001053:Apolipoproteins / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D009043:Motor Activity; D009333:Neck / Q000033:anatomy & histology; D050177:Overweight / Q000097:blood / Q000503:physiopathology*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
chemical_list: D001053:Apolipoproteins; D001786:Blood Glucose; D002784:Cholesterol; D006442:Glycated Hemoglobin; D014280:Triglycerides; C517652:hemoglobin A1c protein, human