title: [Precursors of Pancreatic cancer: Intraepithelial Neoplasia (PanIN) and Intraductal Papillary Mucinous Neoplasms (IPMN)].
abstract: Pancreatic Intraepithelial Neoplasia (PanIN1-3) and Intraductal Papillary Mucinous Neoplasms (IPMN) putative precursors of and associated to pancreatic cancer represent a distinct, however pathologically heterogenous entity. Recently a new classification and nomenclature was established. We review the clinicopathologic and cytogenetic characteristics of PanIN and IPMN highlighting the nonaggressive biological behavior of intraepithelial and intraductal neoplasms which, in part explain their favorable prognosis.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar II. sz. Sebészeti Klinika, Budapest. lednic@kut.sote.hu
authors.forename: György
authors.initials: G
authors.lastname: Ledniczky
authors.forename: Gábor
authors.initials: G
authors.lastname: Bognár
authors.forename: Bíborka
authors.initials: B
authors.lastname: Bereczky
authors.forename: Loránd
authors.initials: L
authors.lastname: Barabás
authors.forename: Pál
authors.initials: P
authors.lastname: Ondrejka
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000737:chemistry / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis; D021441:Carcinoma, Pancreatic Ductal / Q000737:chemistry / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000473:pathology*; D020869:Gene Expression Profiling; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008207:Lymphatic Metastasis; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000473:pathology*; D011230:Precancerous Conditions / Q000737:chemistry / Q000473:pathology*; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor