[Prognostic value of structural and functional changes in the left ventricle with respect to coronary heart diseases].
This study was designed to investigate structural and functional changes in the left ventricle of subjects at high risk of cardiovascular disorders and to assess their prognostic value with respect to coronary heart diseases. A total of 124 subjects with risk factors of cardiovascular diseases and without them were examined by isometric stress Doppler echocardiography, 24 hour Holter monitoring, and veloergometry. Duration of the study was 3 years. It was shown that subjects of the high risk group experienced growth of left ventricular myocardial mass, thinning of the ventricular wall, dilatation and spherization of the intraventricular cavity, impaired contractility and relaxation of the left ventricle. The walk test revealed asynergic areas in the left ventricle, reduced ejection fraction, and impaired diastolic function; these changes are considered to be negative prognostic factors of coronary heart disease.
Shopin
A N
AN
Khovaeva
Ia B
IaB
D000293:Adolescent; D000328:Adult; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D018450:Disease Progression; D025401:Echocardiography, Stress / Q000379:methods; D015716:Electrocardiography, Ambulatory; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D011379:Prognosis; D016277:Ventricular Function, Left / Q000502:physiology*; D020257:Ventricular Remodeling / Q000502:physiology*; D055815:Young Adult