title: The improvement of middle ear ventilation by laser ablation of the epipharyngeal eustachian tube: a prospective study.
abstract: A long-lasting dysfunction of the eustachian tube seems to be the etiologic origin for development of chronic otitis media (COM) with mesotympanic perforation, otitis media with effusion (OME), and chronic atelectasis of the middle ear. Surgical interventions in the middle ear generally treat the sequelae of the tube dysfunction but not the dysfunction itself. This prospective clinical study investigated how far fiber-guided laser ablation of the posterior half of the epipharyngeal tubal ostium led to better middle ear ventilation in the otologic disease patterns mentioned below. There were 38 adult patients included in the analysis. The patients in one group had a perforated tympanic membrane [COM before primary tympanoplasty (n = 14) or revision tympanoplasty (n = 5)]; the patients in a second group had an intact eardrum [OME resistant to therapy (n = 3), with an atelectasis of the middle ear (n = 2) or problems of pressure equalization with fast changes in ambient pressure (diving, flying) (n = 14)]. Laser ablation of the posterior half of the epipharyngeal tubal ostium was performed, generally with local anesthesia, if tubal function testing was pathologic (Valsalva maneuver, passive tube opening, tympanogram). In patients with COM the procedure was performed 8 weeks before the middle ear surgery. All patients were checked 8 weeks postoperatively and in the course of the following year. The intervention seemed to have had a positive effect on tube function in 68.4% of patients operated on (P = 0.001). In 26 of the 38 patients that had undergone operation, an improvement the results of tubal function tests could be seen in the postoperative follow-up. In the COM group the Valsalva maneuver improved in 14 of 19 patients (73.6%) (P = 0.001), and the passive tube opening improved in nine of 18 patients (50%). In the group with an intact eardrum the Valsalva maneuver improved in 13 of 18 patients (72.2%) (P = 0.001). The resulting condition remained stable after 1 year. None of the patients showed any complications as a result of the therapy. Minimally invasive shaping of the distal eustachian tube under topical anesthesia can be recommended for patients with the above-mentioned diagnoses who have pathologic middle ear ventilation. Especially prior to tympanoplasties, and especially in otologic revision procedures, where middle ear ventilation is a prerequisite for successful otologic surgery, the function of the eustachian tube can be optimized in 70% of the patients, particularly if there are pathological findings (tubal tonsil, narrow orifice of the tubal ostium, adenoids). The placement of permanent ear tubes in adults with recurrent OME can also be avoided by the procedure described. The resultant conditions remained stable for the next year. Patients with tympanic ventilation problems due to rapid pressure changes (flying, diving) can also benefit from this procedure.
authors.affiliation: Ear, Nose & Throat Clinic and Polyclinics, Charité Campus Mitte, School of Medicine Berlin, Berlin, Germany. benedikt.sedlmaier@charite.de
authors.forename: B
authors.initials: B
authors.lastname: Sedlmaier
authors.forename: A
authors.initials: A
authors.lastname: Pomorzev
authors.forename: A
authors.initials: A
authors.lastname: Haisch
authors.forename: P
authors.initials: P
authors.lastname: Halleck
authors.forename: H
authors.initials: H
authors.lastname: Scherer
authors.forename: O
authors.initials: O
authors.lastname: Göktas
mesh_terms: D000328:Adult; D000368:Aged; D001274:Atmospheric Pressure; D005064:Eustachian Tube / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008876:Middle Ear Ventilation / Q000379:methods*; D010033:Otitis Media / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D011446:Prospective Studies; D018058:Tympanic Membrane Perforation / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D014636:Valsalva Maneuver; D055815:Young Adult