Conjugated estrogens (Premarin) vaginal cream.
An old conjugated estrogens vaginal cream (Premarin Vaginal Cream--Wyeth) has been newly approved by the FDA specifically for treatment of moderate to severe dyspareunia due to vulvar and vaginal atrophy associated with menopause. Synthetic conjugated estrogens A vaginal cream (Barr) has also been approved for this indication, but has not yet been marketed.
D001284:Atrophy; D004347:Drug Interactions; D004414:Dyspareunia / Q000188:drug therapy* / Q000209:etiology; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D014621:Vagina / Q000473:pathology; D014622:Vaginal Creams, Foams, and Jellies; D014844:Vulva / Q000473:pathology
D004967:Estrogens; D004966:Estrogens, Conjugated (USP); D014622:Vaginal Creams, Foams, and Jellies