title: Gait characteristics and functional assessment of children with type I osteogenesis imperfecta.
abstract: The purpose of this study was to improve the evaluation process of children with type I Osteogenesis Imperfecta (OI) by providing a quantitative comparison of gait and selected functional assessments to age-matched controls. A 14-camera Vicon Motion Analysis System was used for gait analysis along with selected functional assessments (Pediatric Outcomes Data Collection Instrument [PODCI], Functional Assessment Questionnaire [FAQ], Faces Pain Scale-Revised [FPS-R]) conducted on 10 subjects with type I OI and 22 age-matched healthy controls. The results of the OI group demonstrated abnormal gait parameters including increased double support, delayed foot off, reduced ankle range of motion and plantarflexion during third rocker, along with greater ankle power absorption during terminal stance and reduced ankle power generation during push off. The functional assessment scores of the OI group were similar to the control group for basic mobility and function, but were lower than their peers in the sports and physical function category. The evaluation of individuals with OI by means of gait analysis and selected functional assessments, along with an accurate biomechanical model of the lower extremities, is proposed to better understand and predict OI disability and improve quality of life.
authors.affiliation: Shriners Hospitals for Children, Chicago, Illinois, USA. agraf@shrinenet.org
authors.forename: Adam
authors.initials: A
authors.lastname: Graf
authors.forename: Sahar
authors.initials: S
authors.lastname: Hassani
authors.forename: Joseph
authors.initials: J
authors.lastname: Krzak
authors.forename: Angela
authors.initials: A
authors.lastname: Caudill
authors.forename: Ann
authors.initials: A
authors.lastname: Flanagan
authors.forename: Ruta
authors.initials: R
authors.lastname: Bajorunaite
authors.forename: Gerald
authors.initials: G
authors.lastname: Harris
authors.forename: Peter
authors.initials: P
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000843:Ankle Joint / Q000502:physiology; D001696:Biomechanical Phenomena; D002648:Child; D004185:Disability Evaluation; D005260:Female; D005684:Gait / Q000502:physiology*; D006621:Hip Joint / Q000502:physiology; D006801:Humans; D007719:Knee Joint / Q000502:physiology; D008297:Male; D051346:Mobility Limitation; D010013:Osteogenesis Imperfecta / Q000503:physiopathology*; D010808:Physical Examination; D011788:Quality of Life; D016059:Range of Motion, Articular / Q000502:physiology; D011795:Surveys and Questionnaires