Contribution of leptin to the formation of neuroleptic obesity in patients with schizophrenia during antipsychotic therapy.
We studied the dynamics of serum leptin level and some anthropometric values in patients with schizophrenia treated with risperidone, olanzapine, and clozapine showed gender-dependent specific correlations between the studied parameters.
Gorobets
L N
LN
Department of Psychiatric Endocrinology, Moscow Institute of Psychiatry, Federal Agency for Health Care and Social Development, Russia. gorobetsln@mail.ru
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D003024:Clozapine / Q000009:adverse effects; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood / Q000209:etiology*; D000077152:Olanzapine; D018967:Risperidone / Q000009:adverse effects; D012563:Schizophrenia, Paranoid / Q000097:blood / Q000150:complications* / Q000188:drug therapy*; D012737:Sex Factors; D055815:Young Adult
D014150:Antipsychotic Agents; D020738:Leptin; D001569:Benzodiazepines; D003024:Clozapine; D018967:Risperidone; D000077152:Olanzapine