title: Using genetic tools to understand plant phosphoinositide signalling.
abstract: Phosphoinositides (PIs) are regulatory lipids that control various physiological processes in eukaryotic organisms. As in other eukaryotes, the plant PI system is a central regulator of metabolism. The analysis of mutant plants that lack certain PI species has revealed their physiological relevance; however, knowledge of the factors controlling the distribution of PIs and the effects on their target proteins is still limited. To understand PI functions better, genetic approaches should be combined with biochemical analyses and cell biology, as has been done in several recent publications. Here, I highlight plant-specific physiological processes that are controlled by PIs and suggest future avenues of research. A detailed understanding of the functions and effects of PIs might offer new opportunities for modulating plant growth and hardiness against environmental influences.
authors.affiliation: Department of Plant Biochemistry, Georg-August-University Göttingen, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany. iheilma@uni-goettingen.de
authors.forename: Ingo
authors.initials: I
authors.lastname: Heilmann
mesh_terms: D005821:Genetic Techniques; D010716:Phosphatidylinositols / Q000096:biosynthesis / Q000378:metabolism*; D063245:Plant Development; D010944:Plants / Q000201:enzymology / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D010716:Phosphatidylinositols