title: Extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma of cecum presenting as bright red bleed per rectum--a case report with review of literature.
abstract: BACKGROUND
  Primary colorectal lymphomas are particularly rare and contribute to 0.2% of all colorectal malignancies. Gastroentrointestinal (GI) tract is most commonly a secondary involvement site for non-Hodgkin's lymphoma (NHL). Primary NHL of GI tract are very rare, constituting about 1-4% of all GI tract malignancies. In GI tract, two-thirds of all cases occur in stomach followed by small intestine (9%). Clinical presentation depends upon the site of involvement. Pain, loss of appetite, and weight loss are the most common symptoms, while bleeding occurs more with gastric involvement.
  
  
  METHODS
  We present a case of a female presenting as bright red bleed per rectum who was found to have a cecal mass, subsequently diagnosed as extranodal marginal zone B-cell mucosa-associated lymphoid tissue lymphoma with extensive plasma cell differentiation.
  
  
  CONCLUSIONS
  The diagnosis may be challenging, but a solitary extranodal plasmacytoma and multiple myeloma must be excluded in all such cases.
authors.affiliation: Department of Internal Medicine, Mercy Catholic Medical Center/Drexel University School of Medicine, Mercy Fitzgerald Hospital, 1500 Lansdowne Avenue, Medical Science Building, Darby, PA 19023, USA. rohtesh@yahoo.com
authors.forename: Rohtesh S
authors.initials: RS
authors.lastname: Mehta
authors.forename: Niyati
authors.initials: N
authors.lastname: Modi
authors.forename: Nancy
authors.initials: N
authors.lastname: Sapanara
authors.forename: Prashanth
authors.initials: P
authors.lastname: Ramachandra
authors.forename: Michael
authors.initials: M
authors.lastname: Mikhail
mesh_terms: D002430:Cecal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D011379:Prognosis