Nodular liver lesions involving multiple myeloma: a case report and literature review.
We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal. PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein, beta(2)-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided.
Wu
Xiao-Ning
XN
Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Xuanwu District, Beijing, China.
Zhao
Xin-Yan
XY
Jia
Ji-Dong
JD
D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology*; D014463:Ultrasonography
D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains