Adenocarcinoma arising from the respiratory ciliated epithelium in a benign cystic teratoma of the ovary.
Benign cystic teratoma of the ovary (BCTO) is the most common benign ovarian tumor, accounting for 15-20% of all ovarian tumors. It is usually diagnosed in the third and fourth decades of life. Malignant transformation is rare, occurring in approximately 1-2% of reported cases, with squamous cell carcinoma being the most common form. Adenocarcinoma arising from mature cystic teratoma is extremely rare. We present the patient with a BCTO, where a malignant transformation of respiratory ciliated epithelium resulted in well differentiated adenocarcinoma. Although respiratory epithelium is often found in BCTOs, adenocarcinoma arising from this cell type is uncommon. To our knowledge, this is the fourth reported case of adenocarcinoma arising from the respiratory epithelium of a BCTO.
Song
Yong Jung
YJ
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, 111 Jungbalsan-ro, Ilsandong-gu, Gyeonggi-do, Goyang-si, 410-769, Republic of Korea. song@ncc.re.kr
Ryu
Sang Young
SY
Choi
Suck Chul
SC
Lee
Eui Don
ED
Lee
Kyung Hee
KH
Cho
Soo Youn
SY
D000230:Adenocarcinoma / Q000209:etiology / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology*; D010053:Ovary / Q000473:pathology*; D020545:Respiratory Mucosa / Q000473:pathology; D013724:Teratoma / Q000150:complications / Q000473:pathology*