Identification of cyclophilin as a novel allergen from Platanus orientalis pollens by mass spectrometry.
Oriental plane trees are an important source of airborne allergens in cities of southwest Asia. In spite of extensive studies on Platanus acerifolia allergy, there are no reports on the molecular characterization of pollen allergens from Platanus orientalis trees. In this study, a newly recognized member of cyclophilin family with a molecular weight of 18 kDa was identified as being partly responsible for IgE reactivity of P. orientalis pollen extract.
Pazouki
Nazanin
N
Biology Department, Science and Research Branch, Islamic Azad University (IAU), Tehran, Iran.
Sankian
Mojtaba
M
Leung
Priscilla T Y
PT
Nejadsattari
Taher
T
Khavari-Nejad
Ramezan-Ali
RA
Varasteh
Abdol-Reza
AR
D000485:Allergens / Q000737:chemistry*; D000595:Amino Acid Sequence; D021983:Cyclophilins / Q000737:chemistry*; D004591:Electrophoresis, Polyacrylamide Gel; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010944:Plants / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D000485:Allergens; D021983:Cyclophilins