title: Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997.
abstract: Using archived tumours, those from 1984-1986 and 1996-1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival.
authors.affiliation: Department of Surgery, Crosshouse Hospital, Glasgow Royal Infirmary, Scotland, UK. sylvg82@hotmail.com
authors.forename: S B F
authors.initials: SB
authors.lastname: Brown
authors.forename: E A
authors.initials: EA
authors.lastname: Mallon
authors.forename: J
authors.initials: J
authors.lastname: Edwards
authors.forename: F M
authors.initials: FM
authors.lastname: Campbell
authors.forename: L M
authors.initials: LM
authors.lastname: McGlynn
authors.forename: B
authors.initials: B
authors.lastname: Elsberger
authors.forename: T G
authors.initials: TG
authors.lastname: Cooke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000209:etiology* / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000378:metabolism*; D012923:Social Class; D016019:Survival Analysis; D013997:Time Factors
chemical_list: D011960:Receptors, Estrogen