Prefrontal cortex dysfunction during cognitive tests evidenced by functional near-infrared spectroscopy.
Prefrontal cortex oxygenation changes in response to a verbal fluency task and a visual spatial working memory task were investigated by functional near-infrared spectroscopy (fNIRS) on nine patients with schizophrenia. Four patients were reactive to both tests; five reactive to only one of the two tests, suggesting the importance of reporting fNIRS results for each individual.
Quaresima
Valentina
V
DeparDepartment of Health Sciences, University of L'Aquila, Via Vetoio (Loc. Coppito), 67100 L'Aquila, Italy. vale@univaq.it
Giosuè
Patricia
P
Roncone
Rita
R
Casacchia
Massimo
M
Ferrari
Marco
M
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D009949:Orientation / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology; D017397:Prefrontal Cortex / Q000503:physiopathology*; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D019265:Spectroscopy, Near-Infrared; D014706:Verbal Learning / Q000502:physiology; D055815:Young Adult