title: Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers.
abstract: Enhanced brain reward function could contribute to resilience to trauma. Reward circuitry in active duty, resilient special forces (SF) soldiers was evaluated using functional magnetic resonance imaging during a monetary incentive delay task. Findings in this group of resilient individuals revealed unique patterns of activation during expectation of reward in the subgenual prefrontal cortex and nucleus accumbens area, regions pivotal to reward processes.
authors.affiliation: Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD, 20892, USA. meena.vythi@nih.gov
authors.forename: Meena
authors.initials: M
authors.lastname: Vythilingam
authors.forename: Eric E
authors.initials: EE
authors.lastname: Nelson
authors.forename: Matthew
authors.initials: M
authors.lastname: Scaramozza
authors.forename: Tracy
authors.initials: T
authors.lastname: Waldeck
authors.forename: Gary
authors.initials: G
authors.lastname: Hazlett
authors.forename: Steven M
authors.initials: SM
authors.lastname: Southwick
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Pine
authors.forename: Wayne
authors.initials: W
authors.lastname: Drevets
authors.forename: Dennis S
authors.initials: DS
authors.lastname: Charney
authors.forename: Monique
authors.initials: M
authors.lastname: Ernst
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000502:physiology / Q000503:physiopathology; D015415:Biomarkers; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000706:statistics & numerical data; D008297:Male; D008889:Military Personnel / Q000523:psychology / Q000706:statistics & numerical data*; D009042:Motivation; D009714:Nucleus Accumbens / Q000502:physiology; D010100:Oxygen / Q000097:blood; D017397:Prefrontal Cortex / Q000502:physiology; D055500:Resilience, Psychological; D012201:Reward; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology
chemical_list: D015415:Biomarkers; D010100:Oxygen