title: Developmental outcome of children with enlargement of the cisterna magna identified in utero.
abstract: An enlarged cisterna magna can be identified during routine ultrasound screening in the second half of pregnancy. It is important to be able to give an accurate prognosis. We evaluated the developmental outcome of these children. A total of 29 fetuses with a large cisterna magna identified in utero were compared to 35 children with a normal fetal ultrasound. The children were evaluated by the Gesell Developmental Schedules and the Peabody Developmental Motor Scale. The study group showed a significantly worse performance in the Gesell test. However, the overall performance for both groups was within normal limits. Four children in the study group had a borderline developmental quotient. Both groups performed similarly in the Peabody test. Walking age was significantly delayed in the study group. Children with an enlarged cisterna magna may be at risk for mild developmental delay. In cases of nonisolated enlargement of the cisterna magna, the outcome may be guarded.
authors.affiliation: Department of Neuroscience, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Raheli
authors.initials: R
authors.lastname: Dror
authors.forename: Gustavo
authors.initials: G
authors.lastname: Malinger
authors.forename: Liat
authors.initials: L
authors.lastname: Ben-Sira
authors.forename: Dorit
authors.initials: D
authors.lastname: Lev
authors.forename: Chaim G
authors.initials: CG
authors.lastname: Pick
authors.forename: Tally
authors.initials: T
authors.lastname: Lerman-Sagie
mesh_terms: D016080:Arachnoid Cysts / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D002531:Cerebellum / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000503:physiopathology; D002675:Child, Preschool; D002946:Cisterna Magna / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003072:Cognition Disorders / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D015897:Comorbidity; D003388:Cranial Fossa, Posterior / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003616:Dandy-Walker Syndrome / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D002658:Developmental Disabilities / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D004185:Disability Evaluation; D005260:Female; D005333:Fetus; D006801:Humans; D007223:Infant; D008297:Male; D009421:Nervous System Malformations / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D011247:Pregnancy; D011379:Prognosis; D013346:Subarachnoid Space / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D016216:Ultrasonography, Prenatal / Q000379:methods