Outcomes of NIDEK optical path difference custom ablation treatments (OPDCAT) for myopia with or without astigmatism.
To report refractive and visual acuity outcomes using wavefront-guided optical path difference custom ablation treatments (OPDCAT; NIDEK Co Ltd) for myopia and myopic astigmatism.



One hundred eyes of 50 patients with preoperative manifest refraction spherical equivalent (MRSE) of 4.62+/-1.30 diopters (D) (range: -1.38 to -7.25 D) with mean astigmatism of -0.57+/-0.37 D (range: 0 to -1.75 D) underwent LASIK with OPDCAT. Eyes that had > or =5 microm of irregularity preoperatively underwent additional irregularity treatment (irregularity group) and were compared with eyes that did not undergo irregularity ablation (aspheric group). An independent-samples t test was used to analyze refractive outcomes at 3 months postoperatively. A P value <.05 was considered statistically significant.



The mean postoperative MRSE was 0.18+/-0.35 D (range: -0.63 to 1.00 D). Ninety-six (96%) eyes had uncorrected visual acuity of 20/20 or better and 87 (87%) eyes were within +/-0.50 D of the intended correction. No eyes lost two or more lines of best spectacle-corrected visual acuity (BSCVA), 1 (1%) eye lost one line of BSCVA, and 99 (99%) eyes maintained gained lines of BSCVA. The MRSE changed 0.02 D between 1 and 3 months postoperatively. A statistically significant increase was noted in higher order aberrations in the entire cohort (P<.05) with lower induced higher order aberration and coma aberrations in the irregularity group (P<.05).



LASIK using wavefront-guided OPDCAT ablation with or without irregularity is safe and efficacious for the treatment of myopia with astigmatism. The irregularity treatment induces fewer higher order aberrations than aspheric ablation.
Chen
Shihao
S
School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Wang
Yibo
Y
Wang
Qinmei
Q
D000465:Algorithms; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery*; D003319:Corneal Stroma / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology