[Classification of gastro-entero-pancreatic neuroendocrine tumors].
Tumors of the disseminated/diffuse neuroendocrine system (NET) are characterized by a common phenotype. However, the biology varies according to histomorphology, endocrine symptoms and organ of origin. The WHO classification takes these differences into account and uses a common framework, where the parameters size and extent of invasion vary according to the organ of origin. In order to achieve a further standardization of reporting the European Neuroendocrine Tumor Society (ENETS) recently proposed a tumor-node-metastasis (TNM) staging and grading system for gastro-entero-pancreatic NET.
Perren
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A
Institut für Pathologie und pathologische Anatomie, Klinikum rechts der Isar, Technische Universität München, München, Deutschland. aurel.perren@lrz.tum.de
Schmitt
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A
Komminoth
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P
Pavel
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M
D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003952:Diagnostic Imaging; D004067:Digestive System Neoplasms / Q000145:classification* / Q000175:diagnosis / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D018358:Neuroendocrine Tumors / Q000145:classification* / Q000175:diagnosis / Q000473:pathology; D011379:Prognosis; D009626:Terminology as Topic