Using differential gene expression to study Entamoeba histolytica pathogenesis.
The release of the Entamoeba histolytica genome has facilitated the development of techniques to survey rapidly and to relate gene expression with biology. The association and potential contribution of differential gene expression to the life cycle and the virulence of this protozoan parasite of humans are reviewed here.
Gilchrist
Carol A
CA
Division of Infectious Diseases and International Health, Departments of Medicine, Microbiology and Pathology, University of Virginia, PO Box 801340, Charlottesville, VA 22908-1340, USA.
Petri
William A
WA
D000818:Animals; D004195:Disease Models, Animal; D004748:Entamoeba histolytica / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D004749:Entamoebiasis / Q000469:parasitology; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism; D014774:Virulence
D015800:Protozoan Proteins