title: Erythema induratum of Bazin in a child: evidence for a cell-mediated hyper-response to Mycobacterium tuberculosis.
abstract: Tuberculids are chronic nodular skin eruptions believed to be a systemic reaction to Mycobacterium tuberculosis. We report on a 6-year-old boy with tender subcutaneous lesions on his legs. A tuberculin skin test resulted in 2.5 cm of induration and an interferon-gamma releasing assay was also markedly positive. A diagnosis of erythema induratum of Bazin was confirmed on skin biopsy. The patient was successfully treated with multi-drug antituberculosis therapy.
authors.affiliation: From the Department of Pediatrics, New York University School of Medicine, New York, NY, USA. lightj03@med.nyu.edu
authors.forename: Jennifer
authors.initials: J
authors.lastname: Lighter
authors.forename: Doris B
authors.initials: DB
authors.lastname: Tse
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Li
authors.forename: William
authors.initials: W
authors.lastname: Borkowsky
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D004891:Erythema Induratum / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology; D005076:Exanthema / Q000382:microbiology; D006801:Humans; D007371:Interferon-gamma / Q000097:blood; D007866:Leg; D008297:Male; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000302:isolation & purification; D016133:Polymerase Chain Reaction
chemical_list: D000995:Antitubercular Agents; D007371:Interferon-gamma