title: Ghrelin levels in children with adenoid or chronic tonsil hypertrophies before and after surgery.
abstract: OBJECTIVE
  We aimed to evaluate the ghrelin levels in the children with adenoid or tonsil hyperthrophies.
  
  
  METHODS
  The study included 27 children (17 boys and 10 girls). Mean age was 6.9+/-3.5 years, ranging from 3 to 16. Ghrelin levels in the patients and their weight and height measurements were evaluated before surgery and after 3 months later of the operation.
  
  
  RESULTS
  While 18 (67%) children were operated for adenoid hypertrophy, 9 (33%) children were operated for adenoid and tonsil hypertrophy. It was found that postoperative ghrelin levels were significantly decreased whereas weight and BMI scores were significantly increased (p<0.01). A weak correlation was observed between preoperative ghrelin and weight (r=-0.29). This negative correlation became more profound at the postoperative 3rd month examination (r=0.85) (p<0.01).
  
  
  CONCLUSIONS
  The present study showed that the surgical treatment provides positive contributions on the growing of children with adenoid and tonsil hypertrophies. The ghrelin levels were significantly decreased at the postoperative period in the children, and a negative relationship was observed between the ghrelin levels and the weight. These findings suggest that blood ghrelin levels may be useful as a parameter for following the development of the children.
authors.affiliation: Department of Otolaryngoloy, Meram Faculty of Medicine, Selcuk University, 42080, Meram, Konya, Turkey. drsemakoc@mynet.com
authors.forename: Sema
authors.initials: S
authors.lastname: Koc
authors.forename: Kayhan
authors.initials: K
authors.lastname: Ozturk
authors.forename: Sadik
authors.initials: S
authors.lastname: Buyukbas
authors.forename: Volkan
authors.initials: V
authors.lastname: Kocabas
authors.forename: Bedri
authors.initials: B
authors.lastname: Ozer
authors.forename: Medine
authors.initials: M
authors.lastname: Kara
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D002648:Child; D002908:Chronic Disease; D005260:Female; D054439:Ghrelin / Q000172:deficiency*; D006801:Humans; D006984:Hypertrophy / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D007124:Immunoenzyme Techniques; D008297:Male; D014066:Palatine Tonsil / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D014068:Tonsillectomy
chemical_list: D054439:Ghrelin