title: Thrombocytopenia after total knee arthroplasty.
abstract: Heparin-induced thrombocytopenia is a serious complication during antithromboembolic prophylaxis caused by anti-heparin/platelet factor 4 (PF4) complex antibodies. It typically arises 3 to 15 days after the beginning of therapy and may result in an increased risk of arterial and venous thromboembolism. This article presents a case of thrombocytopenia associated with vein thrombosis in a man who underwent a total knee arthroplasty (TKA).
authors.affiliation: Unità Operativa Ortopedia e Traumatologia II, Azienda Ospedaliera Policlinico Bari, 11 Giulio Cesare Square, 70124 Bari, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Pesce
authors.forename: Vittorio
authors.initials: V
authors.lastname: Patella
authors.forename: Antonio
authors.initials: A
authors.lastname: Scaraggi
authors.forename: Massimo
authors.initials: M
authors.lastname: Petrera
authors.forename: Giulio
authors.initials: G
authors.lastname: Sammarco
authors.forename: Antonio
authors.initials: A
authors.lastname: Spinarelli
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000517:prevention & control*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants; D006493:Heparin