title: Effect of nonlinear three-dimensional optimized reconstruction algorithm filter on image quality and radiation dose: validation on phantoms.
abstract: A new technique called the nonlinear three-dimensional optimized reconstruction algorithm filter (3D ORA filter) is currently used to improve CT image quality and reduce radiation dose. This technical note describes the comparison of image noise, slice sensitivity profile (SSP), contrast-to-noise ratio, and modulation transfer function (MTF) on phantom images processed with and without the 3D ORA filter, and the effect of the 3D ORA filter on CT images at a reduced dose. For CT head scans the noise reduction was up to 54% with typical bone reconstruction algorithms (H70) and a 0.6 mm slice thickness; for liver CT scans the noise reduction was up to 30% with typical high-resolution reconstruction algorithms (B70) and a 0.6 mm slice thickness. MTF and SSP did not change significantly with the application of 3D ORA filtering (P > 0.05), whereas noise was reduced (P < 0.05). The low contrast detectability and MTF of images obtained at a reduced dose and filtered by the 3D ORA were equivalent to those of standard dose CT images; there was no significant difference in image noise of scans taken at a reduced dose, filtered using 3D ORA and standard dose CT (P > 0.05). The 3D ORA filter shows good potential for reducing image noise without affecting image quality attributes such as sharpness. By applying this approach, the same image quality can be achieved whilst gaining a marked dose reduction.
authors.affiliation: Department of Biomedical Engineering, Xuanwu Hospital of Capital University of Medical Sciences, No. 45 Changchun Street, Beijing, People's Republic of China 100053. baimei12@yahoo.com
authors.forename: Mei
authors.initials: M
authors.lastname: Bai
authors.forename: Jiuhong
authors.initials: J
authors.lastname: Chen
authors.forename: Rainer
authors.initials: R
authors.lastname: Raupach
authors.forename: Christoph
authors.initials: C
authors.lastname: Suess
authors.forename: Ying
authors.initials: Y
authors.lastname: Tao
authors.forename: Mingchen
authors.initials: M
authors.lastname: Peng
mesh_terms: D000465:Algorithms; D001822:Body Burden; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*