Dermatoscopic characteristics of acrochordon-like basal cell carcinomas in Gorlin-Goltz syndrome.
BACKGROUND
Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons.


OBJECTIVE
We sought to describe the dermatoscopic characteristics of small acrochordon-like or polypoid BCCs in a child with GGS, and to perform histopathologic correlation.


METHODS
Acrochordon-like growths from a child with GGS were studied. Clinical records and digital dermatoscopic images were collected, and excision and histopathologic examination of the most representative lesions were performed.


RESULTS
Some acrochordon-like lesions showed specific dermatoscopic criteria for BCC, including multiple blue-gray globules and arborizing telangiectasia. Other polypoid lesions, especially the smaller ones, exhibited characteristics that suggested BCC, such as isolated blue-gray globules, small blue-gray ovoid nests, and fine elongated telangiectases.


CONCLUSIONS
Conclusions are limited by the small sample size.


CONCLUSIONS
Dermatoscopy may be a useful diagnostic tool to analyze acrochordon-like lesions in children and to facilitate early diagnosis and treatment of BCCs in patients with GGS.
Feito-Rodríguez
Marta
M
Department of Dermatology, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046 Madrid, Spain. marta8marta@hotmail.com
Sendagorta-Cudós
Elena
E
Moratinos-Martínez
Marta
M
González-Beato
María José
MJ
de Lucas-Laguna
Raúl
R
Pizarro
Angel
A
D001478:Basal Cell Nevus Syndrome / Q000175:diagnosis / Q000473:pathology*; D002280:Basal Cell Carcinoma / Q000473:pathology*; D002648:Child; D046169:Dermoscopy; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology*