title: Mastocytosis of the female breast.
abstract: A subset of patients with systemic mastocytosis may manifest with extracutaneous involvement. To the best of our knowledge, mastocytosis of the human breast has not been described. This study reports a case with mastocytosis involving the breasts of a 33-year-old woman associated with mammary hypertrophy (breast mastocytosis). The potential for infiltrating mast cells to mimic lobular carcinoma is emphasized and the relationship to breast hypertrophy in this case is discussed.
authors.affiliation: Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA.
authors.forename: Namrata
authors.initials: N
authors.lastname: Setia
authors.forename: Giovanna M
authors.initials: GM
authors.lastname: Crisi
authors.forename: Liron
authors.initials: L
authors.lastname: Pantanowitz
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D001941:Breast Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis; D018275:Carcinoma, Lobular / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016462:Mammaplasty / Q000379:methods; D008407:Mast Cells / Q000378:metabolism / Q000473:pathology; D034721:Mastocytosis, Systemic / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D055815:Young Adult
chemical_list: D015415:Biomarkers