title: Helical organization in foldable aromatic oligoamides by a continuous hydrogen-bonding network.
abstract: Introduction of a continuous internal hydrogen-bonding network suppressed the conformational flexibility of a series of oligoaromatic foldamers with a lengthened backbone. The helical ordering over up to six aromatic repeating units was established in solution by a 2D NOESY study and in the solid state by an X-ray diffraction method. Computational molecular modeling further corroborates the experimentally observed helical propagation in this class of foldable molecular strands.
authors.affiliation: Department of Chemistry and NUS MedChem Program of the Office of Life Sciences, National University of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Bo
authors.initials: B
authors.lastname: Qin
authors.forename: Yingying
authors.initials: Y
authors.lastname: Shu
authors.forename: Xiuying
authors.initials: X
authors.lastname: Chen
authors.forename: Yeow Kwan
authors.initials: YK
authors.lastname: Yip
authors.forename: Dawei
authors.initials: D
authors.lastname: Zhang
authors.forename: Haibin
authors.initials: H
authors.lastname: Su
authors.forename: Huaqiang
authors.initials: H
authors.lastname: Zeng
mesh_terms: D000577:Amides / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*
chemical_list: D000577:Amides; D011108:Polymers