title: Inflammatory myofibroblastic tumor of the temporal bone: a histologically nonmalignant lesion with fatal outcome.
abstract: BACKGROUND
  Inflammatory myofibroblastic tumor (IMFT) of the temporal bone is an unusual but distinct clinicopathologic entity.
  
  
  METHODS
  We report the case of a 75-year-old patient with an IMFT located in the temporal bone. Symptoms included VI, X, XI, and XII cranial nerves palsies. Computed tomography and magnetic resonance images are described. The lesion was locally aggressive and outcome was fatal. IMFT was identified by analysis of postmortem specimen with histopathologic and immunohistochemical confirmation.
  
  
  CONCLUSIONS
  IMFT can be locally destructive lesions. Involvement of the skull base and cervical spine is indistinguishable from an aggressive infection or a malignant tumor and can be fatal as in our case report. The difficulties in establishing clinicopathologic diagnosis, radiological imaging characteristics, and treatment are discussed.
authors.affiliation: Department of Otorhinolaryngology, Basurto Hospital, Bilbao School of Medicine, University of the Basque Country, Bilbao, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Santaolalla-Montoya
authors.forename: Cosme
authors.initials: C
authors.lastname: Ereño
authors.forename: Aitor
authors.initials: A
authors.lastname: Zabala
authors.forename: Alejandro
authors.initials: A
authors.lastname: Carrasco
authors.forename: A
authors.initials: A
authors.lastname: Martínez-Ibargüen
authors.forename: Jose María
authors.initials: JM
authors.lastname: Sánchez-Fernández