Response of refractory Kawasaki disease to intravenous methylprednisolone.
Refractory Kawasaki disease is difficult to treat and may require retreatment with intravenous immunoglobulins (IVIG), methylprednisolone or other immunological agents. Two cases of refractory Kawasaki disease are described who developed coronary aneurysms despite two courses of IVIG and subsequently responded to intravenous methylprednisolone.
Shah
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Department of Pediatrics, B. J. Wadia Hospital for Children, 240 D Walkeshwar Road, Malabar Hill, Mumbai, India. irashah@pediatriconcall.com
Prabhu
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D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000188:drug therapy / Q000209:etiology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000188:drug therapy*; D017211:Treatment Failure
D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone