Ghrelin levels in children with adenoid or chronic tonsil hypertrophies before and after surgery.
OBJECTIVE
We aimed to evaluate the ghrelin levels in the children with adenoid or tonsil hyperthrophies.


METHODS
The study included 27 children (17 boys and 10 girls). Mean age was 6.9+/-3.5 years, ranging from 3 to 16. Ghrelin levels in the patients and their weight and height measurements were evaluated before surgery and after 3 months later of the operation.


RESULTS
While 18 (67%) children were operated for adenoid hypertrophy, 9 (33%) children were operated for adenoid and tonsil hypertrophy. It was found that postoperative ghrelin levels were significantly decreased whereas weight and BMI scores were significantly increased (p<0.01). A weak correlation was observed between preoperative ghrelin and weight (r=-0.29). This negative correlation became more profound at the postoperative 3rd month examination (r=0.85) (p<0.01).


CONCLUSIONS
The present study showed that the surgical treatment provides positive contributions on the growing of children with adenoid and tonsil hypertrophies. The ghrelin levels were significantly decreased at the postoperative period in the children, and a negative relationship was observed between the ghrelin levels and the weight. These findings suggest that blood ghrelin levels may be useful as a parameter for following the development of the children.
Koc
Sema
S
Department of Otolaryngoloy, Meram Faculty of Medicine, Selcuk University, 42080, Meram, Konya, Turkey. drsemakoc@mynet.com
Ozturk
Kayhan
K
Buyukbas
Sadik
S
Kocabas
Volkan
V
Ozer
Bedri
B
Kara
Medine
M
D000233:Adenoidectomy; D000234:Adenoids / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D002648:Child; D002908:Chronic Disease; D005260:Female; D054439:Ghrelin / Q000172:deficiency*; D006801:Humans; D006984:Hypertrophy / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D007124:Immunoenzyme Techniques; D008297:Male; D014066:Palatine Tonsil / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D014068:Tonsillectomy
D054439:Ghrelin