[Advance of study on vitamin A deficiency and excess associatied with congenital heart disease].
It was demonstrated that Vitamin A may be crucial for heart morphogenesis during pregnancy. Both deficiency and excess of Vitamin A could induce certain congenital heart disease. In the gastrula stage, vitamin A could play a specific role in the process of heart development because of activating many gene regulations, in order to promote heart development. In this article, the advance of mechanism study on vitamin A associated with congenital heart disease were reviewed.
Xing
Xiuya
X
School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China. xiuya_2000@sina.com
Tao
Fangbiao
F
D000818:Animals; D005260:Female; D006330:Heart Defects, Congenital / Q000209:etiology*; D006801:Humans; D009747:Nutritional Physiological Phenomena; D011247:Pregnancy; D011248:Pregnancy Complications; D011297:Prenatal Exposure Delayed Effects; D014801:Vitamin A / Q000097:blood*; D014802:Vitamin A Deficiency / Q000150:complications*
D014801:Vitamin A