title: Gold-catalyzed [4C+3C] intramolecular cycloaddition of allenedienes: synthetic potential and mechanistic implications.
abstract: Efficient at room temperature: The Au complex generated in situ from [(IPr)AuCl] and AgSbF(6) promotes the [4C+3C] intramolecular cycloaddition of allenes and dienes at room temperature, and in a particularly efficient and versatile manner. A DFT study on dimethylallenyl precursors agreed with the formation and cycloaddition of a metal-allyl cation intermediate, and points to the 1,2-hydride shift as the key rate-limiting step.
authors.affiliation: Departamento de Química Orgánica, Universidad de Santiago de Compostela, Facultad de Química, 15782, Santiago de Compostela, Spain.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Trillo
authors.forename: Fernando
authors.initials: F
authors.lastname: López
authors.forename: Sergi
authors.initials: S
authors.lastname: Montserrat
authors.forename: Gregori
authors.initials: G
authors.lastname: Ujaque
authors.forename: Luis
authors.initials: L
authors.lastname: Castedo
authors.forename: Agustí
authors.initials: A
authors.lastname: Lledós
authors.forename: Jose L
authors.initials: JL
authors.lastname: Mascareñas