title: Apparent diffusion coefficient values of middle ear cholesteatoma differ from abscess and cholesteatoma admixed infection.
abstract: A retrospective study was conducted on a cohort of 15 patients who underwent surgery because cholesteatoma or abscess was suspected. All patients had MR imaging prior to surgery with diffusion-weighted images (DWI) from which the apparent diffusion coefficient (ADC) value was calculated. Using this technique, we were able to determine 3 distinct ADC value ranges corresponding to the 3 groups of lesions found at surgery (pure cholesteatoma, cholesteatoma with infection, and abscess or infection). This needs to be confirmed by further studies with a wider range of patients.
authors.affiliation: Department of Radiology, Hautepierre Strasbourg, Strasbourg, France. sebastienthiriat@voila.fr
authors.forename: S
authors.initials: S
authors.lastname: Thiriat
authors.forename: S
authors.initials: S
authors.lastname: Riehm
authors.forename: S
authors.initials: S
authors.lastname: Kremer
authors.forename: E
authors.initials: E
authors.lastname: Martin
authors.forename: F
authors.initials: F
authors.lastname: Veillon
mesh_terms: D000038:Abscess / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D018424:Cholesteatoma, Middle Ear / Q000175:diagnosis*; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult