title: An unusual presentation of Ehlers-Danlos syndrome vascular type with deep vein thrombosis: a case for multidisciplinary management.
abstract: Ehlers-Danlos syndrome (EDS) vascular type typically presents with significant vascular complications such as rupture of blood vessels, gravid uterus, or intestinal perforation. We report on a 24-year-old female that presents with deep vein thrombosis found to be due to compression by a large posterior tibial artery pseudoaneurysm which ultimately leads to the patient's diagnosis. This case highlights the need for a multidisciplinary approach involving vascular surgery, internal medicine, genetics, and other health care providers for patients with vascular type EDS.
authors.affiliation: Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia 22908-0386, USA. slipinski@virginia.edu
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Lipinski
authors.forename: Shawn E
authors.initials: SE
authors.lastname: Lipinski
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kripalani
authors.forename: Lindsay D
authors.initials: LD
authors.lastname: Friesen
authors.forename: Brian S
authors.initials: BS
authors.lastname: Uthlaut
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Braddock
mesh_terms: D017541:Aneurysm, False / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D000792:Angiography; D024061:Collagen Type III / Q000235:genetics; D004535:Ehlers-Danlos Syndrome / Q000145:classification / Q000150:complications* / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D020125:Mutation, Missense; D016909:Tibial Arteries; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000209:etiology*; D055815:Young Adult
chemical_list: C439971:COL3A1 protein, human; D024061:Collagen Type III