[The density of prostate specific antigen of the transition zone as an early predictor of prostate cancer].
The investigation included 98 patients with the level of prostate specific antigen (PSA) of blood serum from 0 to 10 ng/ml and with the diagnosis confirmed by the systemic 12-points prostate biopsy. The data obtained clearly show that the PSA density of the transition zone is a potentially true predictor for the early prostate cancer diagnosis in patients with low and middle PSA level (from 0 to 10 ng/ml). When the threshold level of the PSE density in the transition zone is 0.35 ng/ml/cc, its sensitivity and specificity are higher than these indices for the PSA density.
Topuzov
M E
ME
Prialukhin
A E
AE
Zhivov
A V
AV
Plekhanov
A Iu
AIu
D014408:Biomarkers, Tumor / Q000097:blood*; D001706:Biopsy; D018450:Disease Progression; D006801:Humans; D008297:Male; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen