title: Chemical constituents of the stems of Ephedra sinica.
abstract: A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of Ephedra sinica, a famous traditional Chinese herbal medicine. The structures of 1 and 2 were determined by spectroscopic methods, including 1D- and 2D-NMR experiments as well as HR-EI-MS analysis.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine, Ministry of Education), Beijing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.forename: An-Jun
authors.initials: AJ
authors.lastname: Deng
authors.forename: Guan-Hua
authors.initials: GH
authors.lastname: Du
authors.forename: Jin-Lan
authors.initials: JL
authors.lastname: Zhang
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Li
authors.forename: Hai-Lin
authors.initials: HL
authors.lastname: Qin
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D029790:Ephedra sinica / Q000737:chemistry*; D004809:Ephedrine / Q000031:analogs & derivatives / Q000302:isolation & purification; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D054199:Pseudoephedrine / Q000302:isolation & purification
chemical_list: C539876:1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester; D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D009281:Naphthalenes; C041707:N-methylephedrine; D054199:Pseudoephedrine; D004809:Ephedrine