title: Aortic valve replacement in a diseased bicuspid valve eleven years after transplantation.
abstract: Cardiac allotransplantation is subject to a number of chronic complications that may limit graft survival. These include allograft coronary artery disease, renal dysfunction, hypertension, and malignancy, which are largely due to the immuno-modulatory and adverse effects of transplant medications. Reoperation for native allograft disease progression is a rarer phenomenon. We report a case of aortic valve replacement for bicuspid aortic valve stenosis that occurred in a patient more than ten years after cardiac transplantation.
authors.affiliation: Department of Surgery, The Johns Hopkins Hospital, Blalock 618, 600 North Wolfe Street, Baltimore, MD 21287-4618, USA. djoyce4@jhmi.edu
authors.forename: David L
authors.initials: DL
authors.lastname: Joyce
authors.forename: Stuart D
authors.initials: SD
authors.lastname: Russell
authors.forename: John V
authors.initials: JV
authors.lastname: Conte
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Cattaneo
mesh_terms: D001024:Aortic Valve Stenosis / Q000209:etiology / Q000601:surgery*; D002114:Calcinosis / Q000209:etiology / Q000601:surgery*; D016027:Heart Transplantation / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014184:Transplantation, Homologous; D016896:Treatment Outcome