title: Arterial pressure management and carotid endarterectomy.
abstract: Acute perioperative changes in arterial pressure occur frequently, particularly in patients with cardiovascular disease or those receiving vasoactive medications, or in relation to certain cardiovascular surgical procedures. Both hypo- and hypertension are common in patients undergoing carotid surgery because of unique patho-physiological and surgical factors. Poor arterial pressure control is associated with increased morbidity and mortality after carotid endarterectomy, but good control of arterial pressure is often difficult to achieve in practice. New guidelines have emphasized the benefits of performing carotid surgery urgently in patients with acute neurological symptoms. This strategy may make perioperative arterial pressure control more challenging. However, few specific data are available to guide individual drug therapy. The incidence, implications, and aetiology of haemodynamic instability associated with carotid surgery are reviewed, and some recommendations made for its management. Close monitoring and titration of therapy are probably the most important considerations rather than specific choice of agents.
authors.affiliation: Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford OX3 9DU, UK. mark.stoneham@nda.ox.ac.uk
authors.forename: M D
authors.initials: MD
authors.lastname: Stoneham
authors.forename: J P
authors.initials: JP
authors.lastname: Thompson
mesh_terms: D000758:Anesthesia / Q000379:methods; D017704:Baroreflex / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000150:complications; D019990:Perioperative Care / Q000379:methods*; D011311:Pressoreceptors / Q000502:physiology; D012307:Risk Factors