title: Accuracy of 64-slice CT coronary angiography: our initial experience.
abstract: OBJECTIVE
  The objective of our study was to evaluate the diagnostic accuracy of 64-slice computed tomography coronary angiography to detect haemodynamically significant stenosis (>50% luminal narrowing) in comparison to invasive coronary angiography and further analyze the result accounting for heart rate, coronary calcification and location of lesion in the coronary tree.
  
  
  RESULTS
  Forty patients (39 male, 1 female; mean age 50.9 years) underwent both CT coronary angiography and invasive coronary angiography with in a gap of one day. All vessels were included in the study and no patient was excluded due to high heart rate. On per-segment based analysis with invasive coronary angiography as the gold standard, CT coronary angiography correctly identified 62 out of 78 significant stenoses with an overall sensitivity of 79.5% (62 of 78), specificity of 98.5% (532 of 540), positive predictive value of 88.6% (62 of 70) and negative predictive value of 97.1% (532 of 548).
  
  
  CONCLUSIONS
  Our result suggests that 64-slice CT coronary angiography has high diagnostic accuracy to detect haemodynamically significant stenosis.
authors.affiliation: Diwan Chand Imaging Research Center, New Delhi, India. drashutoshprakash@gmail.com
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Prakash
authors.forename: Kulbir
authors.initials: K
authors.lastname: Ahlawat
authors.forename: U A
authors.initials: UA
authors.lastname: Kaul
authors.forename: Sanjay
authors.initials: S
authors.lastname: Tyagi
authors.forename: Bharat
authors.initials: B
authors.lastname: Aggarwal
authors.forename: Sriram
authors.initials: S
authors.lastname: Rajan
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Kathuria
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000503:physiopathology; D023921:Coronary Stenosis / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013997:Time Factors