[In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea].
OBJECTIVE
To study the preliminary antioxidant and antimicrobial activities of polysaccharide extracted from Lycoris aurea.


METHODS
The scavenging activities of the polysaccharide in vitro on superoxide radical (O2-*), hydroxyl radical (*OH), alkyl radical (R*) and hydrogen peroxide (H2O2) were investigated by modified chemical systems. Meanwhile, the antimicrobial activities were tested using paper-discagar diffusion method.


RESULTS
In general, the antioxidant activities of the polysaccharide were lower compared with Vc. However, the scavenging effects to *OH and H2O2 were parallel to Vc. Meanwhile, polysaccharide from Lycoris aurea had strong antimicrobial activities against Micrococcus luteus, Bacillus pumilus and Staphylococcus aureus.


CONCLUSIONS
The polysaccharide extracted from L. aurea can scavenge *OH and H2O2 effectively and inhibit Gram-positive bacterias.
Ru
Qiao-Mei
QM
School of Life Sciences, Xiamen University, Xiamen 361005, China. ruqiaomei@xmu.edu.cn
Pei
Zhen-Ming
ZM
Zheng
Hai-Lei
HL
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D005609:Free Radicals / Q000378:metabolism*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006861:Hydrogen Peroxide / Q000378:metabolism; D017665:Hydroxyl Radical / Q000378:metabolism; D031426:Lycoris / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013481:Superoxides / Q000378:metabolism
D000900:Anti-Bacterial Agents; D000975:Antioxidants; D005609:Free Radicals; D011134:Polysaccharides; D013481:Superoxides; D017665:Hydroxyl Radical; D006861:Hydrogen Peroxide