title: Evaluation of rapid urine test for the detection of Helicobacter pylori infection in the Vietnamese population.
abstract: OBJECTIVE
  This study attempted to assess the value of the RAPIRUN test for the diagnosis of Helicobacter pylori infection in the Vietnamese population.
  
  
  METHODS
  We recruited 148 Vietnamese patients undergoing upper gastrointestinal endoscopy during which five gastric biopsies were taken; blood and urine samples were collected from each patient. Helicobacter pylori infection status was determined by a combination of three different methods, including culture, immunohistochemistry, and serum ELISA. RAPIRUN tests were performed using urine samples.
  
  
  RESULTS
  The sensitivity, specificity, and accuracy of the RAPIRUN test in these Vietnamese patients were 79.5, 90.7, and 84.5%, respectively.
  
  
  CONCLUSIONS
  The RAPIRUN test is useful for the diagnosis of H. pylori infection in the Vietnamese population, showing high specificity, acceptable sensitivity, non-invasiveness, convenience, and rapidity.
authors.affiliation: Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu-city, Oita 879-5593, Japan. ngltung@med.oita-u.ac.jp
authors.forename: Lam Tung
authors.initials: LT
authors.lastname: Nguyen
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Uchida
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Tsukamoto
authors.forename: Tuan Dung
authors.initials: TD
authors.lastname: Trinh
authors.forename: Long
authors.initials: L
authors.lastname: Ta
authors.forename: Dang Quy Dung
authors.initials: DQ
authors.lastname: Ho
authors.forename: Takeshi
authors.initials: T
authors.lastname: Matsuhisa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Uchida
authors.forename: Akiko
authors.initials: A
authors.lastname: Takayama
authors.forename: Naoki
authors.initials: N
authors.lastname: Hijiya
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Okimoto
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kodama
authors.forename: Kazunari
authors.initials: K
authors.lastname: Murakami
authors.forename: Toshio
authors.initials: T
authors.lastname: Fujioka
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Moriyama
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000652:urine*; D015169:Colony Count, Microbial; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000652:urine; D016480:Helicobacter pylori / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D014744:Vietnam; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D011933:Reagent Kits, Diagnostic