[Clinical utility of epidural anesthesia during and after major spine surgery].
BACKGROUND
Spine surgery causes severe postoperative pain, but epidural anesthesia is not commonly used. The main reason is that it might cause some complications, such as motor block and infection. We compared the efficacy of epidural infusion with hypodermic infusion.


METHODS
Thirty-two patients scheduled for spine surgery were included in the study. Patients were randomly assigned to receive either continuous epidural infusion (ropivacaine 0.18% and fentanyl 45.5 microg x ml(-1) at 2 ml x hr(-1)) or continuous hypodermic infusion via a patient-controlled analgesia system (morphine 0.04 mg x kg(-1) x ml(-1) at 0.5 ml x hr(-1); bolus: 0.5 ml x hr(-1)). We investigated pain and nausea by using visual analogue scale after surgery.


RESULTS
Patient data did not differ between groups. Pain and nausea scores were significantly lower in the epidural infusion group than in the hypodermic infusion group. Epidural infusion did not cause any complications. The incidence of nausea in the hypodermic infusion group was 13 times as high as that in the epidural infusion group. Similarly, the incidence of nausea in female patients was 13 times as high as that in male patients.


CONCLUSIONS
Continuous epidural infusion provides superior analgesia even if high-dose local anesthetics are not used. Besides, it decreases the incidence of nausea because systemic administration of opioids can be avoided.
Ukita
Makoto
M
Department of Anesthesia, Keiyu Hospital, Yokohama 220-8521.
Sato
Masato
M
Sato
Kimiyasu
K
Fukuya
Toshihiko
T
Yoneyama
Mitsuhiko
M
Sakuma
Takahiro
T
Masuda
Junichi
J
D000368:Aged; D000577:Amides / Q000008:administration & dosage; D015360:Analgesia, Epidural; D016058:Analgesia, Patient-Controlled; D000779:Anesthetics, Local / Q000008:administration & dosage; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011446:Prospective Studies; D000077212:Ropivacaine; D013131:Spine / Q000601:surgery*
D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D005283:Fentanyl