title: A prospective study on coping strategies and quality of life in patients after stroke, assessing prognostic relationships and estimates of cost-effectiveness.
abstract: OBJECTIVE
  To examine the prognostic value of coping strategies of patients after stroke at time of discharge on quality of life approximately one year later. In addition, we estimated the maximum cost of improving quality of life by enhancing coping strategies using strict assumptions.
  
  
  METHODS
  Eighty patients with a stroke completed several questionnaires, at discharge to home and 9-12 months later (follow-up). Questionnaires measured quality of life, coping strategies Tenacious Goal Pursuit and Flexible Goal Adjustment. First, a regression analysis was carried out predicting quality of life at follow-up from coping strategies at discharge. Secondly, a maximum in terms of acceptable cost was calculated for several possible effect sizes.
  
  
  RESULTS
  Both coping strategies at discharge were positively associated with quality of life at follow-up. With regards to cost-effectiveness, a medium effect size would result in an increase in quality of life of approximately 10%. The maximum acceptable cost of an intervention for a single patient is therefore set at euro2500, assuming a benefit of one year and a cost per quality adjusted life year of euro25,000.
  
  
  CONCLUSIONS
  Coping strategies at discharge are predictive of quality of life one year later. The costs of improving quality of life are thought to be within the limits that determine a cost-effective intervention.
authors.affiliation: Department of Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, The Netherlands. a.darlington@erasmusmc.nl
authors.forename: Anne-Sophie E
authors.initials: AS
authors.lastname: Darlington
authors.forename: Diederik W J
authors.initials: DW
authors.lastname: Dippel
authors.forename: Gerard M
authors.initials: GM
authors.lastname: Ribbers
authors.forename: Romke
authors.initials: R
authors.lastname: van Balen
authors.forename: Jan
authors.initials: J
authors.lastname: Passchier
authors.forename: Jan J V
authors.initials: JJ
authors.lastname: Busschbach
mesh_terms: D000223:Adaptation, Psychological; D000368:Aged; D003362:Cost-Benefit Analysis; D005260:Female; D005500:Follow-Up Studies; D017048:Health Care Costs; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D020521:Stroke / Q000191:economics / Q000523:psychology*; D000071939:Stroke Rehabilitation; D011795:Surveys and Questionnaires