title: Extended-spectrum beta-lactamase-producing Enterobacteriaceae in a Malian orphanage.
abstract: We show high rates of extended-spectrum beta-lactamase-producing Enterobacteriaceae carriage among the staff and children at an orphanage in Bamako, Mali. Enterobacteriaceae colonized in 100% and 63%, respectively, of the 38 children and 30 adults studied. Use of antimicrobial drugs appeared excessive and inappropriate; decontamination and hygiene protocols were also questioned.
authors.affiliation: Brest University Hospital, Brest, France. didier.tande@chu-brest.fr
authors.forename: Didier
authors.initials: D
authors.lastname: Tandé
authors.forename: Nelle
authors.initials: N
authors.lastname: Jallot
authors.forename: Flabou
authors.initials: F
authors.lastname: Bougoudogo
authors.forename: Tracey
authors.initials: T
authors.lastname: Montagnon
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Gouriou
authors.forename: Jacques
authors.initials: J
authors.lastname: Sizun
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017028:Caregivers / Q000706:statistics & numerical data; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology; D002648:Child; D054540:Child, Orphaned / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D008302:Mali / Q000453:epidemiology; D019372:Orphanages; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases