Extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma of cecum presenting as bright red bleed per rectum--a case report with review of literature.
BACKGROUND
Primary colorectal lymphomas are particularly rare and contribute to 0.2% of all colorectal malignancies. Gastroentrointestinal (GI) tract is most commonly a secondary involvement site for non-Hodgkin's lymphoma (NHL). Primary NHL of GI tract are very rare, constituting about 1-4% of all GI tract malignancies. In GI tract, two-thirds of all cases occur in stomach followed by small intestine (9%). Clinical presentation depends upon the site of involvement. Pain, loss of appetite, and weight loss are the most common symptoms, while bleeding occurs more with gastric involvement.


METHODS
We present a case of a female presenting as bright red bleed per rectum who was found to have a cecal mass, subsequently diagnosed as extranodal marginal zone B-cell mucosa-associated lymphoid tissue lymphoma with extensive plasma cell differentiation.


CONCLUSIONS
The diagnosis may be challenging, but a solitary extranodal plasmacytoma and multiple myeloma must be excluded in all such cases.
Mehta
Rohtesh S
RS
Department of Internal Medicine, Mercy Catholic Medical Center/Drexel University School of Medicine, Mercy Fitzgerald Hospital, 1500 Lansdowne Avenue, Medical Science Building, Darby, PA 19023, USA. rohtesh@yahoo.com
Modi
Niyati
N
Sapanara
Nancy
N
Ramachandra
Prashanth
P
Mikhail
Michael
M
D002430:Cecal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D011379:Prognosis