title: [A case of unresectable advanced gastric cancer with Trousseau syndrome].
abstract: Cancer-related coagulopathy is known as Trousseau syndrome with a poor prognosis. A 55-year-old woman was revealed to have gastric cancer (cT3 cN3, cStage IV) with deep vein thrombosis and pulmonary embolism. A curative operation was impossible so she was treated with systemic chemotherapy using S-1 combined with an anticoagulant agent (warfarin). Some studies indicated that the interaction between S-1 and warfarin might cause strong effects of their mutual interaction. Although the dose of warfarin had to be decreased, this patient was able to take both drugs safely without this severe adverse effect until a shift to palliative therapy.
authors.affiliation: Dept. of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine.
authors.forename: Shougo
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ishiguro
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Hanada
authors.forename: Takenori
authors.initials: T
authors.lastname: Takahata
authors.forename: Jugoh
authors.initials: J
authors.lastname: Itoh
authors.forename: Akira
authors.initials: A
authors.lastname: Taniguchi
authors.forename: Shinsaku
authors.initials: S
authors.lastname: Fukuda
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002272:Carcinoembryonic Antigen / Q000097:blood; D016099:Endoscopy, Gastrointestinal; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011655:Pulmonary Embolism / Q000097:blood / Q000150:complications*; D013274:Stomach Neoplasms / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D013577:Syndrome; D013923:Thromboembolism / Q000097:blood / Q000150:complications*; D014057:Tomography, X-Ray Computed
chemical_list: D002272:Carcinoembryonic Antigen