Association between maternal seafood consumption before pregnancy and fetal growth: evidence for an association in overweight women. The EDEN mother-child cohort.
Studies in countries with high seafood consumption have shown a benefit on fetal growth and child development. The objective of our study was to determine the association between seafood consumption in French pregnant women and fetal growth. Pregnant women included in the EDEN mother-child cohort study completed two food frequency questionnaires on their usual diet in the year before and during the last 3 months of pregnancy (n = 1805). Fetal circumferences were measured by ultrasound and anthropometry at birth. Variables were compared across tertiles of the mother's seafood consumption using multiple linear regression to adjust for confounding variables. Analyses were stratified by maternal overweight status because of an interaction between maternal seafood consumption and her body mass index (P < 0.01). There was no association between seafood intake and fetal growth in the whole sample of women. For overweight women (n = 464), higher consumption of seafood before pregnancy was associated with higher fetal biparietal and abdominal circumferences and anthropometric measures. From the lowest to the highest tertiles, mean birthweight was 167 g higher (P = 0.002). No significant association was found with consumption at the end of pregnancy. In conclusion, high seafood consumption before pregnancy is positively associated with fetal growth in overweight women.
Drouillet
Peggy
P
INSERM Unit 780, 16 avenue Paul Vaillant Couturier, Villejuif cedex, France. peggy.drouillet@inserm.fr
Kaminski
Monique
M
De Lauzon-Guillain
Blandine
B
Forhan
Anne
A
Ducimetière
Pierre
P
Schweitzer
Michel
M
Magnin
Guillaume
G
Goua
Valérie
V
Thiébaugeorges
Olivier
O
Charles
Marie-Aline
MA
D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D002657:Child Development / Q000502:physiology; D004032:Diet; D015525:Fatty Acids, Omega-3 / Q000378:metabolism; D005260:Female; D047109:Fetal Development; D005396:Fish Products; D005602:France; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D039382:Maternal Nutritional Physiological Phenomena; D009035:Mothers; D050177:Overweight; D011247:Pregnancy; D017747:Seafood / Q000706:statistics & numerical data*; D012758:Shellfish; D011795:Surveys and Questionnaires; D055815:Young Adult
D015525:Fatty Acids, Omega-3