[Updates on severe traumatic brain injury management].
Traumatic brain injury (TBI) is an important reason of morbidity-mortality all over the world, affecting young males more and generating Public Health problem. Unfortunately, the advances in the pathophysiology knowledge have not followed a similar development in therapeutic options, there currently not being any contrasted neuroprotectants. In this article, we have reviewed the epidemiology, pathophysiology and therapeutic measures used in the management of patient with severe TBI. The general measures as well as those aimed at controlling intracranial hypertension, the role of the surgery and some more innovative therapeutic options currently under evaluation in these patients are analyzed.
Alted López
Emilio
E
UCI Trauma, Servicio de Medicina Intensiva, Hospital Universitario 12 de Octubre, Madrid, España. ealted.hdoc@salud.madrid.org
Aznárez
Susana Bermejo
SB
Fernández
Mario Chico
MC
D055371:Acute Lung Injury / Q000209:etiology / Q000517:prevention & control; D000293:Adolescent; D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D001925:Brain Damage, Chronic / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D001930:Brain Injuries / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D000075202:Contraindications; D019468:Disease Management; D004322:Drainage; D005260:Female; D005334:Fever / Q000209:etiology / Q000628:therapy; D005392:First Aid; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007036:Hypothermia, Induced; D019586:Intracranial Hypertension / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D008297:Male; D009465:Neuromuscular Agents / Q000627:therapeutic use; D018696:Neuroprotective Agents / Q000627:therapeutic use; D019635:Neurosurgical Procedures; D012307:Risk Factors; D055815:Young Adult
D000700:Analgesics; D006993:Hypnotics and Sedatives; D009465:Neuromuscular Agents; D018696:Neuroprotective Agents