title: Update on anesthetic management for pneumonectomy.
abstract: OBJECTIVE
  Pneumonectomy has the highest perioperative risk among common pulmonary resections. The purpose of this review is to update clinicians on the importance of anesthetic management for these patients.
  
  
  RESULTS
  Two complications associated with increased perioperative mortality are relevant to anesthetic management: postoperative arrhythmias and acute lung injury. The geriatric population is particularly at risk for arrhythmias. Adequate preoperative cardiac assessment and drug prophylaxis may decrease this risk. Patients with decreased respiratory function are at increased risk for acute lung injury. The use of large tidal-volume ventilation during anesthesia may increase this risk. There is a trend to better outcomes in centers with larger surgical volumes.
  
  
  CONCLUSIONS
  Patients should have a preoperative assessment of their respiratory function in three areas: lung mechanical function, pulmonary parenchymal function and cardiopulmonary reserve. Interventions that have been shown to decrease the incidence of respiratory complications include cessation of smoking, physiotherapy and thoracic epidural analgesia. Extrapleural pneumonectomy and sleeve pneumonectomy are surgical variations that place specific increased demands on the anesthesiologist. The rare but treatable complication of cardiac herniation must always be remembered as a potential cause of life-threatening hemodynamic instability in the early postoperative period.
authors.affiliation: Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada. peter.slinger@uhn.on.ca
authors.forename: Peter
authors.initials: P
authors.lastname: Slinger
mesh_terms: D000758:Anesthesia; D000818:Animals; D006321:Heart / Q000502:physiology; D006801:Humans; D008168:Lung / Q000502:physiology; D011013:Pneumonectomy / Q000009:adverse effects; D011652:Pulmonary Circulation; D015656:Respiratory Mechanics