title: Medulloblastoma mimicking Lhermitte-Duclos disease on MRI and CT.
abstract: BACKGROUND
  Although previous reports purport that the unique magnetic resonance imaging (MRI) features of Lhermitte-Duclos disease (LDD) obviates the need for biopsy, medulloblastoma can have an indistinguishable imaging appearance.
  
  
  METHODS
  We present a patient who suffered from a medulloblastoma that demonstrated no enhancement and had imaging characteristics that were indistinguishable from LDD. This atypical imaging appearance, which could potentially be confused with LDD, may lead to misdiagnosis and inappropriate treatment in the absence of tissue sampling.
  
  
  CONCLUSIONS
  In those patients where imaging is highly suggestive of LDD but lack other manifestations of Cowden syndrome, biopsy is required and advanced imaging with magnetic resonance spectroscopy (MRS) should be strongly considered.
authors.affiliation: Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA. andougla@iupui.edu
authors.forename: Annette C
authors.initials: AC
authors.lastname: Douglas-Akinwande
authors.forename: Troy D
authors.initials: TD
authors.lastname: Payner
authors.forename: Eyas M
authors.initials: EM
authors.lastname: Hattab
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005729:Ganglioneuroma / Q000000981:diagnostic imaging / Q000473:pathology*; D006223:Hamartoma Syndrome, Multiple / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D015192:Infratentorial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome