[Serial episodes of gastric and cecal perforation in a patient with Behcet's disease involving the whole gastrointestinal tract: a case report].
Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions. Involvement of the central nervous system, vessels, and intestines in BD often leads to a poor prognosis. Digestive manifestations in BD have been reported in up to 1-60% of cases, although the rate varies in different countries. The most frequent extra-oral sites of gastrointestinal involvement are the ileocecal region and the colon. Gastric or esophageal involvement is reported to be very rare. Moreover, there have been no reports on the simultaneous involvement of the esophagus, stomach, ileum, and colon. Here, we present a 55-year-old Korean man with intestinal BD and multiple ileal and colonic ulcerations complicated by perforation, gastric ulcer with bleeding followed by perforation, and esophageal ulcers with bleeding.
Shin
Dong Yeob
DY
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Cheon
Jae Hee
JH
Park
Jae Jun
JJ
Kim
Hoguen
H
Kim
Tae Il
TI
Lee
Yong Chan
YC
Kim
Nam Kyu
NK
Kim
Won Ho
WH
D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D002429:Cecal Diseases / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D016145:Endoscopy, Digestive System; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis*; D006471:Gastrointestinal Hemorrhage; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000473:pathology; D013276:Stomach Ulcer / Q000150:complications / Q000473:pathology