title: 900 MHz electromagnetic field exposure affects qualitative and quantitative features of hippocampal pyramidal cells in the adult female rat.
abstract: The effects of electromagnetic fields (EMFs) emitted by mobile phones on humans hold special interest due to their use in close proximity to the brain. The current study investigated the number of pyramidal cells in the cornu ammonis (CA) of the 16-week-old female rat hippocampus following postnatal exposure to a 900 megahertz (MHz) EMF. In this study were three groups of 6 rats: control (Cont), sham exposed (Sham), and EMF exposed (EMF). EMF group rats were exposed to 900 MHz EMF (1 h/day for 28 days) in an exposure tube. Sham group was placed in the exposure tube but not exposed to EMF (1 h/day for 28 days). Cont group was not placed into the exposure tube nor were they exposed to EMF during the study period. In EMF group rats, the specific energy absorption rate (SAR) varied between 0.016 (whole body) and 2 W/kg (locally in the head). All of the rats were sacrificed at the end of the experiment and the number of pyramidal cells in the CA was estimated using the optical fractionator technique. Histopathological evaluations were made on sections of the CA region of the hippocampus. Results showed that postnatal EMF exposure caused a significant decrease of the pyramidal cell number in the CA of the EMF group (P<0.05). Additionally, cell loss can be seen in the CA region of EMF group even at qualitative observation. These results may encourage researchers to evaluate the chronic effects of 900 MHz EMF on teenagers' brains.
authors.affiliation: Department of Anatomy, Rize University School of Medicine, Rize, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Bas
authors.forename: Ersan
authors.initials: E
authors.lastname: Odaci
authors.forename: Suleyman
authors.initials: S
authors.lastname: Kaplan
authors.forename: Niyazi
authors.initials: N
authors.lastname: Acer
authors.forename: Kagan
authors.initials: K
authors.lastname: Ucok
authors.forename: Serdar
authors.initials: S
authors.lastname: Colakoglu
mesh_terms: D000818:Animals; D002452:Cell Count / Q000379:methods; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005260:Female; D006624:Hippocampus / Q000473:pathology* / Q000528:radiation effects*; D017966:Pyramidal Cells / Q000473:pathology* / Q000528:radiation effects*; D051381:Rats; D017208:Rats, Wistar