title: New anthraquinone glycosides from the roots of Morinda citrifolia.
abstract: Six new anthraquinone glycosides: digiferruginol-1-methylether-11-O-beta-gentiobioside (1); digiferruginol-11-O-beta-primeveroside (2); damnacanthol-11-O-beta-primeveroside (3); 1-methoxy-2-primeverosyloxymethyl-anthraquinone-3-olate (4); 1-hydroxy-2-primeverosyloxymethyl-anthraquinone-3-olate (5); and 1-hydroxy-5,6-dimethoxy-2-methyl-7-primeverosyloxyanthraquinone (6) were isolated from Morinda citrifolia (Rubiaceae) roots together with four known anthraquinone glycosides. The structures of the new compounds were established using spectral methods. For five of the new compounds, the sugar is attached via the hydroxymethyl group of the anthraquinone C-2 carbon. This type of bond is rarely found for anthraquinone glycosides isolated from natural sources.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan. kamiya@pharm.kobegakuin.ac.jp
authors.forename: Kohei
authors.initials: K
authors.lastname: Kamiya
authors.forename: Wakako
authors.initials: W
authors.lastname: Hamabe
authors.forename: Shogo
authors.initials: S
authors.lastname: Tokuyama
authors.forename: Toshiko
authors.initials: T
authors.lastname: Satake
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D032066:Morinda / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000880:Anthraquinones; D006027:Glycosides; D010936:Plant Extracts