[A case of recurrence after curative total gastrectomy for gastric cancer successfully treated by combination chemotherapy with CPT-11 and CDDP].
A male in his sixties underwent total gastrectomy for gastric cancer in August, 2002. After surgery, he underwent 4 courses of adjuvant chemotherapy with S-1. About 2 years after the surgery, PET-CT detected liver metastasis and lymph node metastasis, so treatment with CPT-11+CDDP was started with the following regimen: 60 mg/m2 CPT-11 and 30 mg/m2 CDDP biweekly. Five months later, PET-CT revealed that the liver metastasis and lymph node metastasis had disappeared. After judgment of complete response(CR), we continued that treatment every four weeks for one year and every eight weeks for another one year. The patient was followed without any recurrence in January, 2007. For this case, PET-CT was effective for planning the treatment and assessing its response.
Fujimoto
Hiroto
H
Dept. of Surgery, Yamagata Saisei Hospital.
Urayama
Masahiro
M
Kawaguchi
Kiyoshi
K
Ohta
Keiji
K
Seo
Nobuo
N
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D012008:Recurrence; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin