99mTc-red blood cells SPECT and planar scintigraphy in the diagnosis of hepatic hemangiomas.
The aim of the study is the assessment of the value of SPECT (single photon emission computerized tomography) using 99mTc-labeled red blood cells in the detection of liver hemangioma, in comparison to planar imaging. With planar red blood cell scintigraphy, sensitivity of the method was 76%, specificity 98%, positive predictive value 98% and negative predictive value 79%. With SPECT, sensitivity of the method was 95%, specificity 98%, positive predictive value 98% and negative predictive value 94%. The smallest lesion detected by planar red blood cell scintigraphy was 1.2 cm, and with SPECT red blood cell scintigraphy 0.8 cm. The use of 99mTc-labeled red blood cells SPECT improved the sensitivity much more in smaller lesions (0.8 to 2 cm), than in bigger ones (2-5 cm). SPECT with radiolabeled red blood cells significantlyy improves the results of scintigraphic findings, especially in the small lesions.
Artiko
M V
MV
Institute for Nuclear Medicine, Clinical Center of Serbia.
Sobić-Saranović
P D
PD
Perisić-Savić
S M
SM
Stojković
V M
VM
Radoman
B I
BI
Knezević
S J
SJ
Petrović
S N
SN
Obradović
B V
BV
Milović
V
V
D000328:Adult; D004912:Erythrocytes; D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013670:Sodium Pertechnetate Tc 99m; D015899:Tomography, Emission-Computed, Single-Photon; D055815:Young Adult
D013670:Sodium Pertechnetate Tc 99m