title: [How to confirm acute fatty liver of pregnancy in case of emergency].
abstract: Acute fatty liver of pregnancy (AFLP) is a rare disease of which prognosis could be adverse if diagnosis is delayed. Certain diagnosis is sometimes made complex because of undercurrent symptoms with pre-eclampsia or hemolysis, elevated liver enzyme, low platelet (HELLP) syndrome. Several reports announce an increase of incidence and illustrate cases confirmed by non-invasive methods. They permit early diagnosis and improve morbidity and mortality. Reviewing seven of the most important series of AFLP, we demonstrate how to use ultrasonography or computed tomography scan to confirm AFLP. However, liver biopsy should be realised after delivery in case of uncertain diagnosis.
authors.affiliation: Service de gynécologie-obstétrique et médecine de le reproduction, hôpital Morvan, CHRU de Brest, Brest, France. lionelhomer@yahoo.fr
authors.forename: L
authors.initials: L
authors.lastname: Homer
authors.forename: T
authors.initials: T
authors.lastname: Hebert
authors.forename: J-B
authors.initials: JB
authors.lastname: Nousbaum
authors.forename: Y
authors.initials: Y
authors.lastname: Bacq
authors.forename: M
authors.initials: M
authors.lastname: Collet
mesh_terms: D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005234:Fatty Liver / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D017359:HELLP Syndrome; D006801:Humans; D008099:Liver / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography