A bullous lesion in a neutropenic adolescent.
Ecthyma gangrenosum (EG) is a cutaneous manifestation of bacteremia and has classically been associated with Pseudomonas aeruginosa sepsis. The major risk factor for EG is neutropenia, and it is important to recognize that infectious lesions in neutropenic patients may lack the classic inflammatory features of infection in normal hosts. Ecthyma gangrenosum can be the herald of severe sepsis in neutropenic children.
Doughty
Cara B
CB
Department of Pediatrics, Sections of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA.
Cruz
Andrea T
AT
Kaplan
Sheldon L
SL
D000293:Adolescent; D001768:Blister / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D019818:Clavulanic Acid / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009503:Neutropenia / Q000150:complications*; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D013848:Thigh; D013982:Ticarcillin / Q000627:therapeutic use
D005839:Gentamicins; D019818:Clavulanic Acid; D013982:Ticarcillin