title: Bioptics with LASIK flap first for the treatment of high ametropia.
abstract: To report the safety and predictability of an alternate sequence of the bioptics procedure.
  
  
  
  In this prospective study of 50 eyes, phakic intraocular lenses (IOLs) and pseudophakic IOLs were implanted, followed by LASIK. The corneal flap was created, followed by lens implantation 3 days later. Laser ablation was performed to the stromal bed 3 months later. Fifty eyes with varying degrees of refractive error (range of manifest refraction spherical equivalent [MRSE], -19.50 to +8.50 diopters [D]) were treated. Follow-up ranged from 3 months to 4 years postoperatively.
  
  
  
  No intra- or postoperative complications occurred. Postoperatively, MRSE ranged from -0.75 to +0.50 D. Mean residual refractive astigmatism ranged from +0.25 to +1.50 D postoperatively. Postoperative uncorrected visual acuity was 20/20 or better in 82% (41/50) of eyes and 20/40 or better in 98% (49/50) of eyes. No eyes experienced a loss of best spectacle-corrected visual acuity postoperatively.
  
  
  
  This modification of the sequence of procedures for bioptics provided safe and predictable outcomes.
authors.affiliation: Tbilisi State Medical University, Tbilisi, Georgia. modernoptics@hotmail.com
authors.forename: Merab L
authors.initials: ML
authors.lastname: Dvali
authors.forename: Nana A
authors.initials: NA
authors.lastname: Tsinsadze
authors.forename: Bella V
authors.initials: BV
authors.lastname: Sirbiladze
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D006956:Hyperopia / Q000503:physiopathology / Q000601:surgery*; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D019654:Lens Implantation, Intraocular; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011446:Prospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult