[Replacement renal therapy in complex treatment of severe acute pancreatitis].
The purpose of this study was to retrospectively analyze the efficiency of replacement renal therapy (RRT) in multimodality treatment for severe acute pancreatitis (SAP) concurrent with a systemic inflammatory response and multiple organ failure/dysfunction. The authors analyzed the results of treating 55 patients (14 women and 41 men) aged 22 to 72 years (mean 43.5 +/- 16.4 years) treated at the intensive care units of Moscow City Clinical Hospital Fifty-Two in January 1, 2000, to December 31, 2006. All the patients had multiple organ dysfunctions with the involvement of 2 to 5 organs (median 4 (3; 4) and were on RRT. RRT may be successfully used in multimodality treatment for SAP provided that the dose of dialysis is at least 35 ml/kg/hour. The severe condition rated by the APACHE HII and SAPS II scales and the dialysis dose of less than 35 ml/kg/hour are independent risk factors of death in SAP patients.
Podkorytova
O L
OL
Tomilina
N A
NA
Bibkov
B T
BT
Vtorenko
V I
VI
Shirinskiĭ
V G
VG
Loktev
V V
VV
Fedorova
N D
ND
Chura
I S
IS
Rodnikov
S E
SE
D018806:APACHE; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D010195:Pancreatitis / Q000150:complications / Q000276:immunology / Q000401:mortality / Q000628:therapy*; D017582:Renal Replacement Therapy / Q000379:methods*; D012189:Retrospective Studies; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult