Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins.
The pyrrolo[2,3-c]carbazole , the common core of the marine alkaloids known as the dictyodendrins, has been synthesised. The sequence is based on a Suzuki cross-coupling reaction between the pyrrole fragment and the indole fragment , followed by tandem photochemical 6pi-electrocyclization/aromatisation.
Ayats
Carles
C
Institute for Research in Biomedicine, Barcelona Scientific Park-University of Barcelona, Baldiri Reixach 10-12, E-08028 Barcelona, Spain.
Soley
Roger
R
Albericio
Fernando
F
Alvarez
Mercedes
M
D000470:Alkaloids; D002227:Carbazoles / Q000138:chemical synthesis*; D007211:Indoles / Q000737:chemistry; D008386:Marine Biology; D010777:Photochemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
D000470:Alkaloids; D002227:Carbazoles; D007211:Indoles; D011758:Pyrroles; C505029:dictyodendrin B; C523041:dictyodendrin C; C523042:dictyodendrin E