title: [REM sleep behavior disorder (RBD) in dementia with lewy bodies (DLB)--a study using short sleep-disorder questionnaire for DLB (SDQ-DLB)].
abstract: OBJECTIVE
  To assess the validity of the short sleep-disorder questionnaire for dementia with Lewy bodies (SDQ-DLB). SDQ-DLB is a newly developed structured interview containing 10 items for assessing REM sleep behavior disorder (RBD) in DLB.
  
  
  METHODS
  The subjects were 23 patients with a clinical diagnosis of Alzheimer's disease (AD), 21 patients with possible DLB, and 7 patients with probable DLB.
  
  
  METHODS
  SDQ-DLB was administered to reliable informants representing each patient. The frequency of positive endorsement for each item was compared between the 3 patient groups.
  
  
  RESULTS
  The following 3 items of the questionnaire significantly differentiated between the patient groups: item 1 (Has the patient ever acted or talked in his/her nocturnal sleep while he/she seems to be half asleeps?), item 5 (Has the patient ever sat or got up on the bed (or the futon mattress) in his/her nocturnal sleep?) and item 6 (Has the patient ever gone out of the bed (or the futon mattress) to ambulate or to act violently in his/her nocturnal sleep while he/she seems to be half asleep?). The 7-point composite score of items 1 to 7 with 2 to 3 cut-off points showed 71% sensitivity in the patients with probable DLB, 51%sensitivity in the patients with possible DLB, and 91% specificity in the AD patients.
  
  
  CONCLUSIONS
  The composite score of the 7 items of SDQ-DLB could distinguish AD from DLB with sufficient sensitivity and specificity. SDQ-DLB may be useful to evaluate RBD in DLB.
authors.affiliation: Department of Speech Therapy, School of Health Sciences, Niigata University of Health and Welfare, Japan.
authors.forename: Kuniya
authors.initials: K
authors.lastname: Matsumura
authors.forename: Chie
authors.initials: C
authors.lastname: Ichino
authors.forename: Yuri
authors.initials: Y
authors.lastname: Kudou
authors.forename: Naoko
authors.initials: N
authors.lastname: Tachibana
authors.forename: Toru
authors.initials: T
authors.lastname: Imamura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications / Q000175:diagnosis*; D008297:Male; D020187:REM Sleep Behavior Disorder / Q000175:diagnosis* / Q000209:etiology; D011795:Surveys and Questionnaires