Congenital cytomegalovirus infection associated with severe lung involvement in a preterm neonate: a causal relationship?
We report a preterm neonate with congenital cytomegalovirus (CMV) infection associated with severe lung involvement progressing to early chronic lung disease (CLD) and death. The present case represents the earliest and the most severe lung involvement depending on recurrent maternal CMV infection reported in the literature. Neonatal mortality and progression to early CLD should be considered in the list of possible neonatal sequelae resulting from recurrent maternal CMV infection.
Koklu
Esad
E
Division of Neonatology, Department of Pediatrics, Gulhane Military Medical Academy, Ankara, Turkey. esadsena@yahoo.com.tr
Karadag
Ahmet
A
Tunc
Turan
T
Altun
Demet
D
Sarici
S Umit
SU
D000328:Adult; D002908:Chronic Disease; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000175:diagnosis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000821:virology*; D008171:Lung Diseases / Q000175:diagnosis / Q000821:virology*; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000821:virology*; D011263:Pregnancy Trimester, Third