title: One sensor fits all--a new approach in monitoring brain physiology.
abstract: Oxygen plays a pivotal role as a nutrient to the brain. Monitoring partial pressure of oxygen (ptO2) has been shown to correlate with outcome after brain injury if certain tissue-ptO2-goals can be achieved. Oxford Optronix has recently developed a new fiber-optic based sensor (MPBS) with a large tissue sampling volume and long-term stability up to 10 days. Direct comparison of the MPBS sensor with the Licox system was performed using an in-vitro and in-vivo model. No statistically significant differences between the MPBS and the Licox sensor in different settings were found. The response times to a sudden drop in ptO2 was faster for the MPBS than for the Licox probes (time of 80% signal change; 65 +/- 11 vs 110 +/- 14 s; p<0.05).
authors.affiliation: Department of Pediatrics, HELIOS Klinikum Wuppertal, Witten/Herdecke University, Wuppertal, Germany, 42283.
authors.forename: H
authors.initials: H
authors.lastname: Doll
authors.forename: N
authors.initials: N
authors.lastname: Davies
authors.forename: S L E
authors.initials: SL
authors.lastname: Douglas
authors.forename: F
authors.initials: F
authors.lastname: Kipfmueller
authors.forename: M
authors.initials: M
authors.lastname: Maegele
authors.forename: R
authors.initials: R
authors.lastname: Pauly
authors.forename: G
authors.initials: G
authors.lastname: Woebker
authors.forename: A N
authors.initials: AN
authors.lastname: Obeid
authors.forename: H
authors.initials: H
authors.lastname: Truebel
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D002245:Carbon Dioxide / Q000378:metabolism; D008991:Monitoring, Physiologic / Q000379:methods*; D013552:Swine
chemical_list: D002245:Carbon Dioxide