Long-term clinical effects of magnetic resonance imaging in patients with coronary artery stent implantation.
OBJECTIVE
We sought to investigate the early and late effects of magnetic resonance imaging (MRI) on stent thrombosis and major adverse coronary events after coronary artery stent (CAS) implantation at a long-term follow-up period.


METHODS
Forty-three patients (28 men, mean age 63+/-10 years) who underwent CAS implantation before MRI examination were included. MRI was performed on a 1.5-T MR-system with a phased array multicoil. An average of 1.3 stents per patient were implanted (1-4 stents). More than one MRI was performed for two patients. Patients who underwent MRI within 8 weeks after the procedure were included in the early-term group (17 patients), and those who underwent MRI after 8 weeks were included in the late-term group (26 patients).


RESULTS
Mean follow-up period was 36+/-15 months. There was no acute or subacute stent thrombosis. Late stent thrombosis that resulted in acute myocardial infarction was observed in a patient from the early group after an operation for prostate hyperplasia 5 months after MRI, and the patient underwent percutaneous coronary artery angioplasty. De-nova lesion was observed in four patients in the early group and two patients in the late group (P=0.14). In-stent restenosis was recorded in two patients in the early group and three patients in the late group (P=0.98). Composite major adverse cardiac events (acute coronary syndrome, myocardial infarction, death, and cerebrovascular event) were observed in seven of the early-group patients (41%), and in six of the late-group patients (23%) (P=0.20).


CONCLUSIONS
MRI can be safely performed in patients with CAS implantation both in the early and late course, and is not associated with an increased risk of major adverse clinical cardiac events at long-term follow-up.
Kaya
Mehmet Gungor
MG
Department of Cardiology, Erciyes University, Kayseri, Turkey.
Okyay
Kaan
K
Yazici
Huseyin
H
Sen
Nihat
N
Tavil
Yusuf
Y
Turkoglu
Sedat
S
Timurkaynak
Timur
T
Ozdemir
Murat
M
Cemri
Mustafa
M
Yalcin
Ridvan
R
Cengel
Atiye
A
D054058:Acute Coronary Syndrome / Q000209:etiology; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects* / Q000295:instrumentation*; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000209:etiology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000473:pathology / Q000628:therapy*; D023903:Coronary Restenosis / Q000209:etiology; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008279:Magnetic Resonance Imaging / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D016016:Proportional Hazards Models; D018570:Risk Assessment; D015607:Stents; D013927:Thrombosis / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome