title: Incidental renal artery calcifications: a study of 350 consecutive abdominal computed tomography scans.
abstract: BACKGROUND
  Calcifications in arteries are thought to represent atherosclerosis.
  
  
  METHODS
  Consecutive abdominal tomographic scans performed during a 4-month period were evaluated and assessed for renal artery calcifications (RAC). Scans that showed calcifications were evaluated for renal artery narrowing and for various characteristics of the atherosclerotic plaque.
  
  
  RESULTS
  Of 350 consecutive examinees, 43% were men, 40% had hypertension and 38% had hypercholesterolaemia. The age was 61 +/- 13 years. Aortic calcifications were found in 54% and RAC in 102 (29%), of whom 53 had bilateral calcifications. Subjects with RAC were older, 72 +/- 6 versus 55 +/- 12 years. Adjusted odds ratios of RAC were 2.2 (95% CI 1.1-4.6) for male gender, 2.4 (1.2-4.8) for hypertension and 2.9 (1.4-5.8) for hypercholesterolaemia, whereas family history of hypertension was protective with 0.5 (0.3-0.9). All patients with calcified renal arteries had aortic calcifications, versus 35% of those without RAC. A significant correlation was found between the severity of calcifications and the degree of renal artery narrowing (r = 0.7), and also between the presence of bilateral calcifications and a high-grade narrowing.
  
  
  CONCLUSIONS
  RAC strongly relates to atherosclerosis. Calcifications and artery narrowing may have a role in the pathogenesis of hypertension. Bilateral calcifications suggest atherosclerotic renal artery stenosis.
authors.affiliation: Department of Medicine, Hadassah-Hebrew University Medical Center, Mount-Scopus, Jerusalem, Israel.
authors.forename: Lior
authors.initials: L
authors.lastname: Tolkin
authors.forename: Michael
authors.initials: M
authors.lastname: Bursztyn
authors.forename: Iddo Z
authors.initials: IZ
authors.lastname: Ben-Dov
authors.forename: Natalia
authors.initials: N
authors.lastname: Simanovsky
authors.forename: Nurith
authors.initials: N
authors.lastname: Hiller
mesh_terms: D000005:Abdomen; D000368:Aged; D002114:Calcinosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012077:Renal Artery; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000000981:diagnostic imaging*