Nickel-catalyzed highly regio- and stereoselective cross-trimerization between triisopropylsilylacetylene and internal alkynes leading to 1,3-diene-5-ynes.
The first highly selective 1:2 cross-trimerization between triisopropylsilylacetylene and 2 equiv of internal alkynes, leading to 1,3-diene-5-yne compounds, was achieved using the Ni(cod)(2)/P(n)Pr(3) catalyst. Various symmetrical and asymmetrical internal alkynes could be used for the cross-trimerization reaction with high regio- and stereoselectivity.
Ogata
Kenichi
K
Department of Applied Chemistry, Institute of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan. orgchem@kc.chuo-u.ac.jp
Murayama
Hiroyuki
H
Sugasawa
Jun
J
Suzuki
Noriyuki
N
Fukuzawa
Shin-Ichi
S
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000480:Alkynes; D009942:Organometallic Compounds; D012821:Silanes; C551805:triisopropylsilylacetylene; D009532:Nickel