title: Oral carcinoma epidemiology in Paraná State, Southern Brazil.
abstract: Oral carcinoma is the sixth most frequent type of cancer in the world and the seventh most common in Brazil (the country with the highest incidence in Latin America). Mean five-year survival remains one of the lowest among the main cancers, thus justifying studies that contribute to the development of preventive strategies. The aim of this study was to compare the epidemiological, clinical, and histological characteristics of 91 patients with oral carcinoma. Mean age was 58.62 +/- 10.46 years, and male-to-female ratio was 6.6:1.0 (79 men and 12 women). European descendants predominated with 79 patients (86.8%). Eighty-five individuals (93.4%) smoked and 70 (76.9%) consumed alcohol regularly. Anatomical distribution of tumors was: 27 (29.7%) tongue; 18 (19.8%) floor of mouth; 11 (12.1%) oropharynx; and 11 (12.1%) oral mucosa. Fifty-seven patients (62.6%) presented lymph node involvement and three (3.3%) had distant metastases. Surgery and radiotherapy were used in 43.2% of patients. With the exception of the male/female ratio (which was higher), our data are consistent with previous studies on oral carcinoma patients.
authors.affiliation: Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil. rolosi@uol.com.br
authors.forename: Roberta
authors.initials: R
authors.lastname: Losi-Guembarovski
authors.forename: Rodrigo Paes de
authors.initials: RP
authors.lastname: Menezes
authors.forename: Fernando
authors.initials: F
authors.lastname: Poliseli
authors.forename: Vivian Nappi
authors.initials: VN
authors.lastname: Chaves
authors.forename: Hellen
authors.initials: H
authors.lastname: Kuasne
authors.forename: Andrei
authors.initials: A
authors.lastname: Leichsenring
authors.forename: Marcos Euzébio
authors.initials: ME
authors.lastname: Maciel
authors.forename: Alda Losi
authors.initials: AL
authors.lastname: Guembarovski
authors.forename: Benedito W
authors.initials: BW
authors.lastname: Oliveira
authors.forename: Gyl
authors.initials: G
authors.lastname: Ramos
authors.forename: Lauro Toyshi
authors.initials: LT
authors.lastname: Mizuno
authors.forename: Iglenir João
authors.initials: IJ
authors.lastname: Cavalli
authors.forename: Enilze Maria de Souza Fonseca
authors.initials: EM
authors.lastname: Ribeiro
authors.forename: Ilce Mara de Syllos
authors.initials: IM
authors.lastname: Cólus
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects