title: Sleep disorderd breathing and recurrence of cerebrovascular events, case-fatality, and functional outcome in patients with ischemic stroke or transient ischemic attack.
abstract: Ninety one patients with stroke or transient ischemic attack (TIA) were screened for sleep-disordered breathing (SDB). Case fatality, rate of recurrence of cerebrovascular events, and functional outcome were analyzed during a 2-year follow-up. The patients were stratified into groups: without (AH < or =5) and with SDB (AHI >5). SDB was present in 61 (67.7%) patients with stroke or TIA. The rate of recurrence of TIA or stroke in patients with SDB was significantly higher (12 patients, OR=1.52, P<0.05) as compared with patients without SDB (3 patients) within two years of observation. Case-fatality rates were not significantly different (4 patients with SDB and 2 patients without SDB). Our data show that SDB significantly increases the incidence of recurrent cerebrovascular events in patients with TIA or stroke in a two-year follow-up. SDB in patient with stroke or TIA did not influence functional outcome of stroke during the long-term observation.
authors.affiliation: First Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland. rafal.rola@wp.pl
authors.forename: R
authors.initials: R
authors.lastname: Rola
authors.forename: H
authors.initials: H
authors.lastname: Jarosz
authors.forename: A
authors.initials: A
authors.lastname: Wierzbicka
authors.forename: A
authors.initials: A
authors.lastname: Wichniak
authors.forename: P
authors.initials: P
authors.lastname: Richter
authors.forename: D
authors.initials: D
authors.lastname: Ryglewicz
authors.forename: W
authors.initials: W
authors.lastname: Jernajczyk
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000150:complications / Q000401:mortality / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000401:mortality* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000150:complications / Q000401:mortality / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011044:Poland / Q000453:epidemiology; D012008:Recurrence; D012891:Sleep Apnea Syndromes / Q000401:mortality* / Q000503:physiopathology*; D020521:Stroke / Q000209:etiology / Q000401:mortality / Q000503:physiopathology*; D016896:Treatment Outcome