title: Nodular liver lesions involving multiple myeloma: a case report and literature review.
abstract: We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal. PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein, beta(2)-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided.
authors.affiliation: Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Xuanwu District, Beijing, China.
authors.forename: Xiao-Ning
authors.initials: XN
authors.lastname: Wu
authors.forename: Xin-Yan
authors.initials: XY
authors.lastname: Zhao
authors.forename: Ji-Dong
authors.initials: JD
authors.lastname: Jia
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains