title: [Assessment of the level of immunoglobulin E in patients with pyo-inflammatory diseases and its influence on the course of the infectious process].
abstract: The level of immunoglobulin E (IgE) in patients with different pyo-inflammatory diseases was assessed and it was found to elevate in patients with acute appendicitis in 49% of cases, in patients with chronic relapsing furunculosis (CRF) in 41%, with chronic osteomyelitis--in 66.6%. In 8 out of 16 examined patients with the elevated level of IgE there were antibodies to toxocars in titers 1:800, 1:400. No correlation with the IgE level was found in assessing the level of IL-4 and gamma-IFN in blood serum of patients with CRF. In patients with acute appendicitis, CRF and chronic osteomyelitis the elevated level of IgE can be considered as a marker of unfavorable course of pyo-inflammatory diseases. The elevated level of IgE does not influence the oxygen-dependent mechanisms of bactericidal action of neutrophils.
authors.forename: T A
authors.initials: TA
authors.lastname: Druzhinina
authors.forename: B A
authors.initials: BA
authors.lastname: Molotilov
authors.forename: A S
authors.initials: AS
authors.lastname: Ivachev
authors.forename: A V
authors.initials: AV
authors.lastname: Peskov
authors.forename: O A
authors.initials: OA
authors.lastname: Levashova
authors.forename: E V
authors.initials: EV
authors.lastname: Titova
mesh_terms: D000208:Acute Disease; D000888:Antibodies, Anti-Idiotypic / Q000097:blood; D001064:Appendicitis / Q000097:blood* / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D018450:Disease Progression; D005667:Furunculosis / Q000097:blood* / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D010019:Osteomyelitis / Q000097:blood* / Q000276:immunology; D012008:Recurrence
chemical_list: D000888:Antibodies, Anti-Idiotypic; D015415:Biomarkers; D007073:Immunoglobulin E