title: [Fertility prognosis associated to percutaneous testicular biopsy in infertile varicocele patients].
abstract: BACKGROUND
  Varicocele is cause of fertility disorders. The objective was to evaluate usefulness of testicular percutaneous biopsy in the fertility prognosis in patients, who undergone varicocelectomy.
  
  
  METHODS
  A cohort study of 50 patients having undergone varicocelectomy due to varicocele was carried out. Five groups were formed according to testicular damage evaluated by percuta-neous biopsy (stage I through V histological lesions). Pregnancy rate and sperm count results were evaluated per group. ANOVA and Fisher exact test were used.
  
  
  RESULTS
  Patients aged 30.5 +/- 5 years. Spermatic density and motility had improved one year after varicocelectomy. Pregnancies were achieved 13 +/- 9 months later. Fifteen patients impregnated their partners. Fourteen of them (93 %) had stage I, II or III histological damage and only one case had stage IV. Pregnancy probability was greater in the stage I, II or III testicular damage (OR = 9.3, 95 % CI = 11-79, p < 0.021).
  
  
  CONCLUSIONS
  The proposed histological classification of testicular damage allows evaluating fertility prognosis as well as the magnitude of testicular damage in patients with varicocele.
authors.affiliation: Departamento de Cirugía, Hospital General de Zona 1, Instituto Mexicano del Seguro Social, Colima, México. acja@hotmail.com
authors.forename: Alfredo César
authors.initials: AC
authors.lastname: Juárez-Albarrán
authors.forename: Carlos Enrique
authors.initials: CE
authors.lastname: Tene-Pérez
authors.forename: Irma
authors.initials: I
authors.lastname: Maldonado-Villaseñor
authors.forename: Rafael
authors.initials: R
authors.lastname: Casillas-Mesina
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology*; D008297:Male; D011379:Prognosis; D013737:Testis / Q000473:pathology*; D014646:Varicocele / Q000150:complications* / Q000473:pathology*