title: Dose dependence of DNA repair in rainbow trout (Oncorhynchus mykiss) larvae exposed to UV-B radiation.
abstract: We examined survival and DNA damage in rainbow trout larvae (Oncorhynchus mykiss) resulting from a range of sublethal to lethal ultraviolet-B exposures in the presence and absence of photoreactivating radiation. We found that after low, sublethal UV-B exposures trout larvae are quite proficient at photoenzymatic repair but that this capacity decreases exponentially with the total incident UV-B dose. The relationship between the dose dependence of PER and trout development and vulnerability in fisheries and in the natural environment are discussed.
authors.affiliation: Department of Carcinogenesis, The University of Texas MD Andersen Cancer Center, 1808 Park Road 1C, Smithville, TX 78957, USA. dmitchel@mdanderson.org
authors.forename: David L
authors.initials: DL
authors.lastname: Mitchell
authors.forename: Tristan
authors.initials: T
authors.lastname: Adams-Deutsch
authors.forename: Mark H
authors.initials: MH
authors.lastname: Olson
mesh_terms: D000818:Animals; D004249:DNA Damage; D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D007814:Larva / Q000528:radiation effects*; D017686:Oncorhynchus mykiss / Q000254:growth & development*; D014466:Ultraviolet Rays