Lymph node assessment and lymphadenectomy in bladder cancer.
Lymph node status is a key prognostic indicator in patients with bladder cancer, so lymphadenectomy is important for accurate staging. Moreover, lymphadenectomy is curative for some patients with nodal metastases. Although there is evidence that the quality of regional node dissection is associated with oncologic outcome, controversy exists because other factors may also explain this observation. Consequently, there is no consensus regarding the optimal extent of lymphadenectomy and number of nodes that should be assessed.
Sharir
Sharon
S
Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada. s.sharir@utoronto.ca
Fleshner
Neil E
NE
D015653:Cystectomy; D003657:Decision Making; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D009626:Terminology as Topic; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery