title: Genetic diversity of dog breeds: between-breed diversity, breed assignation and conservation approaches.
abstract: Genetic relationships between 61 dog breeds were investigated, using a sampling of 1514 animals and a panel of 21 microsatellite markers. Based on the results from distance-based and Bayesian methods, breed constituted the main genetic structure, while groups including genetically close breeds showed a very weak structure. Depending on the method used, between 85.7% and 98.3% of dogs could be assigned to their breed, with large variations according to the breed. However, breed heterozygosity influenced assignment results differently according to the method used. Within-breed and between-breed diversity variations when breeds were removed were highly negatively correlated (r = -0.963, P < 0.0001), because of the genetic structure of the breed set.
authors.affiliation: AgroParisTech, UMR1236 Génétique et Diversité Animales, Paris, France. gregoire.leroy@agroparistech.fr
authors.forename: G
authors.initials: G
authors.lastname: Leroy
authors.forename: E
authors.initials: E
authors.lastname: Verrier
authors.forename: J C
authors.initials: JC
authors.lastname: Meriaux
authors.forename: X
authors.initials: X
authors.lastname: Rognon
mesh_terms: D000818:Animals; D001499:Bayes Theorem; D001947:Breeding; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004285:Dogs / Q000235:genetics*; D014644:Genetic Variation; D005828:Genetics, Population; D018895:Microsatellite Repeats / Q000235:genetics
chemical_list: D004247:DNA