title: [Serial episodes of gastric and cecal perforation in a patient with Behcet's disease involving the whole gastrointestinal tract: a case report].
abstract: Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions. Involvement of the central nervous system, vessels, and intestines in BD often leads to a poor prognosis. Digestive manifestations in BD have been reported in up to 1-60% of cases, although the rate varies in different countries. The most frequent extra-oral sites of gastrointestinal involvement are the ileocecal region and the colon. Gastric or esophageal involvement is reported to be very rare. Moreover, there have been no reports on the simultaneous involvement of the esophagus, stomach, ileum, and colon. Here, we present a 55-year-old Korean man with intestinal BD and multiple ileal and colonic ulcerations complicated by perforation, gastric ulcer with bleeding followed by perforation, and esophageal ulcers with bleeding.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Dong Yeob
authors.initials: DY
authors.lastname: Shin
authors.forename: Jae Hee
authors.initials: JH
authors.lastname: Cheon
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Park
authors.forename: Hoguen
authors.initials: H
authors.lastname: Kim
authors.forename: Tae Il
authors.initials: TI
authors.lastname: Kim
authors.forename: Yong Chan
authors.initials: YC
authors.lastname: Lee
authors.forename: Nam Kyu
authors.initials: NK
authors.lastname: Kim
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Kim
mesh_terms: D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D002429:Cecal Diseases / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D016145:Endoscopy, Digestive System; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis*; D006471:Gastrointestinal Hemorrhage; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000473:pathology; D013276:Stomach Ulcer / Q000150:complications / Q000473:pathology