title: [Lymphocytic-thrombocytic adhesion and production of blood serum cytokines in rheumatic heart disease].
abstract: OBJECTIVE
  To study changes of cytokine production and lymphocytic-thrombocytic adhesion (LTA) in patients with rheumatic heart disease.
  
  
  METHODS
  Concentrations of interleukine-1beta, interleukine-4, tumor necrosis factor alpha in the blood serum and lymphocytic-thrombocytic adhesion by Yu. A. Vitkovsky's method were measured in 84 patients with rheumatic fever and 26 healthy ones.
  
  
  RESULTS
  A correlation was found between increased production of inflammatory cytokines, lymphocytic-thrombocytic adhesion and activation of rheumatic process.
  
  
  CONCLUSIONS
  A monodirection of changes of inflammatory cytokine production, lymphocytic-thrombocytic adhesion and rheumatic fever activation allows using them as nonspecific diagnostic methods in assessment of inflammation activity.
authors.forename: V V
authors.initials: VV
authors.lastname: Gorbunov
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Tsarenok
authors.forename: I V
authors.initials: IV
authors.lastname: Rosin
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000166:cytology* / Q000276:immunology; D016022:Case-Control Studies; D002448:Cell Adhesion / Q000276:immunology; D016207:Cytokines / Q000097:blood*; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000166:cytology* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000097:blood* / Q000276:immunology; D055815:Young Adult
chemical_list: D016207:Cytokines