TGF-beta uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells.
Thakur
Noopur
N
Sorrentino
Alessandro
A
Heldin
Carl-Henrik
CH
Landström
Maréne
M
D000818:Animals; D006801:Humans; D020930:MAP Kinase Kinase Kinases / Q000378:metabolism*; D008297:Male; D011471:Prostatic Neoplasms / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D048029:TNF Receptor-Associated Factor 6 / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000378:metabolism*; D000099151:MAP Kinase Kinase Kinase 7
D020930:MAP Kinase Kinase Kinases; D048029:TNF Receptor-Associated Factor 6; D016212:Transforming Growth Factor beta; D000099151:MAP Kinase Kinase Kinase 7