Protein function annotation by homology-based inference.
With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.
Loewenstein
Yaniv
Y
Department of Biological Chemistry, The Hebrew University of Jerusalem, Sudarsky Center, Jerusalem 91904, Israel.
Raimondo
Domenico
D
Redfern
Oliver C
OC
Watson
James
J
Frishman
Dmitrij
D
Linial
Michal
M
Orengo
Christine
C
Thornton
Janet
J
Tramontano
Anna
A
D019295:Computational Biology / Q000379:methods*; D011506:Proteins / Q000145:classification / Q000502:physiology*; D017386:Sequence Homology, Amino Acid
D011506:Proteins