Microwave-assisted Cu-catalyzed protodecarboxylation of aromatic carboxylic acids.
An effective protocol has been developed that allows the smooth protodecarboxylation of diversely functionalized aromatic carboxylic acids within 5-15 min. In the presence of at most 5 mol % of an inexpensive catalyst generated in situ from copper(I) oxide and 1,10-phenanthroline, even nonactivated benzoates were converted in high yields and with great preparative ease.
Goossen
Lukas J
LJ
Fachbereich Chemie, Technische Universitat Kaiserslautern, Erwin-Schroedinger-Strasse, D-67663 Kaiserslautern, Germany. goossen@chemie.uni-kl.de
Manjolinho
Filipe
F
Khan
Bilal A
BA
Rodríguez
Nuria
N
D001565:Benzoates / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D003300:Copper; D003653:Decarboxylation; D008872:Microwaves; D010618:Phenanthrolines / Q000737:chemistry; D055668:Photochemical Processes
D001565:Benzoates; D002264:Carboxylic Acids; D010618:Phenanthrolines; D003300:Copper; C025205:1,10-phenanthroline