[Correlation analysis between plasma levels of 25-hydroxy vitamin D3 and osteocalcin in patients with aggressive periodontitis].
OBJECTIVE
To explore the relationship between plasmatic 25-hydroxy vitamin D3 (25OHD3) level and plasmatic osteocalcin level in patients with aggressive periodontitis (AgP).


METHODS
Thirty four AgP patients and 29 healthy controls were included in this study. 25OHD3 and osteocalcin levels in plasma were measured using commercially available radioimmunoassay kits. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were measured using a standard hospital analytical technique.


RESULTS
Plasmatic 25OHD3 level was significantly higher in AgP patients than that in healthy controls (8.65 microg/L vs 3.10 microg/L; P<0.01). Osteocalcin level was also significantly higher in AgP patients than that in healthy subjects (1.0 microg/L vs 0.8 microg/L; P=0.028). AST level was significantly lower in AgP patients than that in healthy controls(20.0 U/L vs 23.0 U/L). No correlations between the plasmatic levels of 25OHD3 and osteocalcin were detected in AgP patients or in healthy controls (r=0.271, P=0.12; r=-0.356, P=0.58).


CONCLUSIONS
Plasmatic 25OHD3 and osteocalcin concentrations were not correlated but might be influenced by AgP.
Liu
Kai-ning
KN
Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Meng
Huan-xin
HX
Tang
Xiao-lin
XL
Xu
Li
L
Zhang
Li
L
Chen
Zhi-bin
ZB
Shi
Dong
D
Feng
Xiang-hui
XH
Lu
Rui-fang
RF
D000293:Adolescent; D000328:Adult; D010520:Aggressive Periodontitis / Q000097:blood*; D002112:Calcifediol / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D015675:Osteocalcin / Q000097:blood*; D055815:Young Adult
D015675:Osteocalcin; D002112:Calcifediol