title: Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction.
abstract: Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We investigated the effects of tissue-cultured mountain ginseng extract (TMGE) on male patients with erectile dysfunction (ED). A double-blind, placebo-controlled study was conducted with 143 patients experiencing ED. Over the course of 8 weeks, one group took 1 000 mg of TMGE twice a day, and the other group took 1,000 mg of placebo twice a day. The effects of the TMGE and the placebo were analyzed using the Korean version of the International Index of Erectile Function (IIEF) questionnaire. A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P<0.05), whereas no significant improvement was observed in the placebo group (P>0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P<0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients.
authors.affiliation: Department of Urology, School of Medicine, Kyung Hee University, Seoul 134-727, Korea.
authors.forename: Tae-Hwan
authors.initials: TH
authors.lastname: Kim
authors.forename: Seung Hyun
authors.initials: SH
authors.lastname: Jeon
authors.forename: Eun-Joo
authors.initials: EJ
authors.lastname: Hahn
authors.forename: Kee-Yoeup
authors.initials: KY
authors.lastname: Paek
authors.forename: Jong Kwan
authors.initials: JK
authors.lastname: Park
authors.forename: Nae Young
authors.initials: NY
authors.lastname: Youn
authors.forename: Hyung-Lae
authors.initials: HL
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D019149:Bioreactors; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005894:Panax / Q000254:growth & development*; D010352:Patient Dropouts; D017060:Patient Satisfaction; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000627:therapeutic use*; D018517:Plant Roots / Q000166:cytology / Q000254:growth & development; D016896:Treatment Outcome
chemical_list: D010936:Plant Extracts