Antimicrobial use and bacterial resistance in neonatal patients.
The neonatal population is at extremely high risk for developing infections. Because of the premature infant's prolonged length of stay, these patients may receive several courses of antibiotics while hospitalized. Although the number of antibiotics used in this population is limited, the dosing regimens must be carefully prescribed and adjusted to account for changing pharmacokinetic parameters. In addition, the development of antimicrobial resistance should always be a concern. The neonatal nurse can help ensure antimicrobial regimens are given appropriately and monitor these regimens for efficacy and toxicity.
Domonoske
Christine
C
Department of Pharmacy Services, Children's Memorial Hermann Hospital, Memorial Hermann Texas Medical Center, 6411 Fannin Street, Houston, TX 77030, USA. Christine.Domonoske@memorialhermann.org
Severson
Karen
K
D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D004334:Drug Administration Schedule; D016903:Drug Monitoring / Q000379:methods / Q000451:nursing; D024881:Drug Resistance, Bacterial / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy / Q000382:microbiology; D015931:Intensive Care, Neonatal / Q000379:methods*; D008826:Microbial Sensitivity Tests; D017283:Neonatal Nursing / Q000379:methods*; D024802:Nurse's Role; D009730:Nursing Assessment / Q000379:methods; D018579:Patient Selection; D012307:Risk Factors
D000900:Anti-Bacterial Agents