title: Time-course monitoring of serum amyloid A in a cat with pancreatitis.
abstract: Time-course changes in the concentration of serum amyloid A (SAA), a major acute phase protein, were measured in a cat with pancreatitis over an 831-day period and compared with changes in WBC count and feline trypsin-like immunoreactivity (fTLI). SAA concentration was increased at the onset of the disease and gradually decreased over 5 days of treatment with an improvement in the clinical condition. In contrast, fTLI concentration and WBC count were not increased at the onset of the disease but increased gradually during the 5 days of treatment. Long-term monitoring from days 68 to 831 revealed a good correlation between SAA concentration and the reoccurrence of clinical signs in the cat; however, WBC count did not increase even with the exacerbation of disease. These findings suggest that the SAA concentration may be a useful marker for evaluating response to treatment and disease exacerbation in feline pancreatitis.
authors.affiliation: Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tamamoto
authors.forename: Koichi
authors.initials: K
authors.lastname: Ohno
authors.forename: Aki
authors.initials: A
authors.lastname: Ohmi
authors.forename: Izumi
authors.initials: I
authors.lastname: Seki
authors.forename: Hajime
authors.initials: H
authors.lastname: Tsujimoto
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000097:blood* / Q000378:metabolism; D002415:Cats; D008297:Male; D010195:Pancreatitis / Q000097:blood* / Q000378:metabolism; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D013997:Time Factors
chemical_list: D000685:Serum Amyloid A Protein