title: Endothelial decompensation following epithelial LASIK with loss of epithelial flap.
abstract: OBJECTIVE
  To report a case that showed endothelial decompensation after epithelial LASIK (epi-LASIK).
  
  
  METHODS
  A 23-year-old woman underwent epi-LASIK surgery to correct refractive error of -4.00 -3.00 x 165 degrees in the right eye and -2.50 -2.00 x 15 degrees in the left eye. Preoperatively, the specular count was 2896 cells/mm2 in the right eye and 3046 cells/mm2 in the left eye. Central corneal thickness (CCT) was 490 microm and 493 microm in the right and left eyes, respectively.
  
  
  RESULTS
  Examination on the first postoperative day revealed diffuse corneal edema with radiating Descemet's folds in the right eye with best spectacle-corrected visual acuity of 20/80. Central corneal thickness was 493 microm and 373 microm in the right and left eyes, respectively, 1 week after surgery. Corneal edema resolved over a period of 3 weeks with healing of the epithelial defect. Endothelial cell count 3 weeks after surgery was 1310 cells/mm2 in the right eye.
  
  
  CONCLUSIONS
  Epi-LASIK can cause significant endothelial cell loss with development of corneal edema.
authors.affiliation: Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Sameer
authors.initials: S
authors.lastname: Kaushal
authors.forename: Gaurav
authors.initials: G
authors.lastname: Prakash
authors.forename: Namrata
authors.initials: N
authors.lastname: Sharma
authors.forename: Jeewan S
authors.initials: JS
authors.lastname: Titiyal
mesh_terms: D000328:Adult; D002452:Cell Count; D015715:Corneal Edema / Q000209:etiology*; D004728:Endothelium, Corneal / Q000473:pathology*; D019573:Epithelium, Corneal / Q000473:pathology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000009:adverse effects*; D009216:Myopia / Q000601:surgery; D013524:Surgical Flaps / Q000473:pathology*; D014792:Visual Acuity