A clinical study of microcirculatory disturbance in Chinese patients with sudden deafness.
CONCLUSIONS
Cochlear microcirculation disturbance is closely associated with sudden deafness.


OBJECTIVE
To investigate the relationship between cochlear microcirculation and sudden deafness.


METHODS
Clinical laboratory parameters (clinical chemistry, hemorheology, hematology, and hemostasis determinations) were studied in 86 patients with sudden deafness and 30 healthy control subjects.


RESULTS
The levels of total cholesterol (TCH), triglyceride (TG), and lipoprotein A were significantly higher in patients with sudden deafness than in control subjects. Plasma viscosity, ratio viscosity of whole blood, reduced viscosity of whole blood, high and low shear relative viscosity of whole blood, index of red blood cells transmutation, and fibrinogen level in the plasma of patients with sudden sensorineural hearing loss (SSNHL) were also significantly elevated in comparison with those in control subjects. White-collar workers with psychological and behavioral abnormalities tend to suffer from sudden deafness.
Lu
Yuan-Yuan
YY
Department of Otolaryngology-Head and Neck Surgery, First Hospital ofAnHui Medical University, HeFei, China.
Jin
Zhe
Z
Tong
Bu-Sheng
BS
Yang
Jian-Ming
JM
Liu
Ye-Hai
YH
Duan
Maoli
M
D000328:Adult; D000368:Aged; D001809:Blood Viscosity; D002784:Cholesterol / Q000097:blood; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000097:blood*; D003639:Hearing Loss, Sudden / Q000097:blood*; D018056:Hemorheology; D006487:Hemostasis; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol