title: An S-locus receptor-like kinase plays a role as a negative regulator in plant defense responses.
abstract: Plant cells often use cell surface receptors to sense environmental changes and then transduce external signals via activated signaling pathways to trigger adaptive responses. In Arabidopsis, the receptor-like protein kinase (RLK) gene family contains more than 600 members, and some of these are induced by pathogen infection, suggesting a possible role in plant defense responses. We previously characterized an S-locus RLK (CBRLK1) at the biochemical level. In this study, we examined the physiological function of CBRLK1 in defense responses. CBRLK1 mutant and CBRLK1-overexpressing transgenic plants showed enhanced and reduced resistance against a virulent bacterial pathogen, respectively. The altered pathogen resistances of the mutant and overexpressing transgenic plants were associated with increased and reduced induction of the pathogenesis-related gene PR1, respectively. These results suggest that CBRLK1 plays a negative role in the disease resistance signaling pathway in Arabidopsis.
authors.affiliation: Division of Applied Life Science (BK21 Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 660-701, Republic of Korea.
authors.forename: Ho Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Mi Soon
authors.initials: MS
authors.lastname: Jung
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Lee
authors.forename: Kyung Eun
authors.initials: KE
authors.lastname: Kim
authors.forename: Hyejin
authors.initials: H
authors.lastname: Byun
authors.forename: Man Soo
authors.initials: MS
authors.lastname: Choi
authors.forename: Hyeong Cheol
authors.initials: HC
authors.lastname: Park
authors.forename: Moo Je
authors.initials: MJ
authors.lastname: Cho
authors.forename: Woo Sik
authors.initials: WS
authors.lastname: Chung
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000502:physiology*; D009154:Mutation; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology*; D010940:Plant Proteins / Q000235:genetics / Q000502:physiology*; D030821:Plants, Genetically Modified / Q000187:drug effects / Q000201:enzymology / Q000235:genetics / Q000382:microbiology; D011494:Protein Kinases / Q000235:genetics / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000502:physiology*; D020156:Salicylic Acid / Q000494:pharmacology; D014158:Transcription, Genetic
chemical_list: D029681:Arabidopsis Proteins; D010940:Plant Proteins; D011494:Protein Kinases; C538996:CBRLK1 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases; C079832:S-receptor kinase; D020156:Salicylic Acid