Trilostane, FAD286, and the role of aldosterone in the central regulation of blood pressure: focus on "Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats".
Funder
John W
JW
D015096:3-Hydroxysteroid Dehydrogenases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000450:Aldosterone / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D003345:Corticosterone / Q000378:metabolism; D019405:Cytochrome P-450 CYP11B2; D013196:Dihydrotestosterone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004791:Enzyme Inhibitors / Q000008:administration & dosage*; D006339:Heart Rate; D006973:Hypertension / Q000201:enzymology* / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D007031:Hypothalamus / Q000187:drug effects / Q000201:enzymology*; D000451:Mineralocorticoid Receptor Antagonists / Q000008:administration & dosage; D051381:Rats; D020303:Rats, Inbred Dahl; D018161:Receptors, Mineralocorticoid / Q000378:metabolism*; D012964:Sodium / Q000134:cerebrospinal fluid; D017673:Sodium Chloride, Dietary / Q000378:metabolism; D013250:Steroid Hydroxylases / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004791:Enzyme Inhibitors; D000451:Mineralocorticoid Receptor Antagonists; D018161:Receptors, Mineralocorticoid; D017673:Sodium Chloride, Dietary; D013196:Dihydrotestosterone; D000450:Aldosterone; D012964:Sodium; D015096:3-Hydroxysteroid Dehydrogenases; D013250:Steroid Hydroxylases; C120361:Cyp11b3 protein, rat; D019405:Cytochrome P-450 CYP11B2; C009954:trilostane; D003345:Corticosterone