title: Characteristic profiles of instrumental activities of daily living in different subtypes of mild cognitive impairment.
abstract: OBJECTIVE
  The purposes of this study were to describe restrictions in instrumental activities of daily living (IADL) in mild cognitive impairment (MCI) and to assess different patterns of IADL in each MCI subtype.
  
  
  METHODS
  A total of 566 participants, those not cognitively impaired (NCI; n = 311) and MCI patients (n = 255), 60-94 years old (71.25 +/- 6.00), were examined. Neuropsychological tests were administered to participants, and each MCI patient was classified into one of four subtypes. They completed the Barthel ADL and Seoul-IADL (S-IADL) for ADL measures.
  
  
  RESULTS
  There was a significant difference between NCI and MCI in terms of total S-IADL scores. ANOVA and a post hoc Dunnett analysis revealed that MCI patients performed significantly worse on four out of a total 15 items (i.e. telephone, transportation, finances and household appliances). ANCOVA showed a significant difference in S-IADL-MCI (4 of 15 items) between NCI and amnestic MCI-multiple domains after adjusting for age, gender, education and Geriatric Depression Scale (F = 4.257, d.f. = 1,556, p = 0.002).
  
  
  CONCLUSIONS
  These findings suggest that scorings of specific IADL items are different in MCI subjects, and these items can possibly help in the identification of MCI subtypes, especially amnestic MCI-multiple domains.
authors.affiliation: Department of Psychiatry, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Kyung Ran
authors.initials: KR
authors.lastname: Kim
authors.forename: Kang Soo
authors.initials: KS
authors.lastname: Lee
authors.forename: Hae-Kwan
authors.initials: HK
authors.lastname: Cheong
authors.forename: Jin-Sup
authors.initials: JS
authors.lastname: Eom
authors.forename: Byoung Hoon
authors.initials: BH
authors.lastname: Oh
authors.forename: Chang Hyung
authors.initials: CH
authors.lastname: Hong
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D009483:Neuropsychological Tests; D012044:Regression Analysis; D012307:Risk Factors; D012959:Socioeconomic Factors