[Non-specific stress-reaction as indicator of radiosensitivity].
The data presented demonstrate possible personal radiosensitivity prognosis according to the immobilization stress response (animal model). It was demonstrated on the Wistar rats that in radiosensitive animals initial oxidative metabolism parameters were higher than in radioresistant ones, and prooxidant-antioxidant balance alteration after non-radiation stress were more evident and kept for a longer period. Those animals had had limphopenia and neutrophilosis. The differences in the response types between radiosensitive and radioresistant animals were due to the blood system reserve abilities, as well as the state of natural mature cells depot, and antioxidant defence enzymes.
Hanzha
O B
OB
Rodionova
N K
NK
Dolyns'kyĭ
H A
HA
Kostiukova
L V
LV
Druzhyna
M O
MO
D000818:Animals; D001854:Bone Marrow Cells / Q000378:metabolism / Q000528:radiation effects; D002374:Catalase / Q000097:blood; D007962:Leukocytes / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D018384:Oxidative Stress / Q000528:radiation effects; D011836:Radiation Tolerance; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood / Q000209:etiology* / Q000378:metabolism; D013997:Time Factors; D014965:X-Rays
D002374:Catalase