Endomyocardial fibrosis as a cause of Budd-Chiari syndrome and fatal pulmonary embolism.
A 24-year-old-man had right-sided heart failure of 3 months' duration. A Doppler echocardiogram revealed atrium and right ventricular enlargement, obliteration of the right ventricular apex, and a mass with an echolucent center measuring 20x21 mm in the right ventricular outlet. He died of pulmonary embolism. At autopsy, a huge organized thrombus obliterating the right ventricular apex passing through the tricuspid valve to the right atrium and then extending to the inferior vena cava up to the suprahepatic veins was seen. Histologically, an intense fibrotic thickening of the endomyocardium extending into the myocardium was observed. Cardiac thrombosis associated with endomyocardial fibrosis should be added to the list of causes of Budd-Chiari syndrome.
Bestetti
Reinaldo B
RB
Setor de Eletrocardiografia, Hospital de Base, Av. Faria Lima, 5544, 15090-000, São José do Rio Preto City, Brazil. rbestetti@netsite.com.br
Silva
Carolina M P D C
CM
Ardito
Sabrina Q
SQ
Theodoropoulos
Tatiana A D
TA
Cury
Patrícia M
PM
Corbucci
Hélio A R
HA
D006502:Budd-Chiari Syndrome / Q000209:etiology* / Q000473:pathology; D003328:Coronary Thrombosis / Q000209:etiology / Q000473:pathology; D004719:Endomyocardial Fibrosis / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000209:etiology* / Q000473:pathology; D055815:Young Adult