BEID: database for sequence-structure-function information on antigen-antibody interactions.
The B-cell Epitope Interaction Database (BEID; http://datam.i2r.a-star.edu.sg/BEID) is an open-access database describing sequence-structure-function information on immunoglobulin (Ig)-antigen interactions. The current version of the database contains 164 antigens, 126 Ig and 189 Ig-antigen complexes extracted from the Protein Data Bank (PDB). Each entry is manually verified, classified, and analyzed for intermolecular interactions between antigens and the corresponding bound Ig molecules. Ig-antigen interaction information that is stored in BEID includes solvent accessibility, hydrogen bonds, non-hydrogen bonds, gap volume, gap index, interface area and contact residues. The database can be searched with a user-friendly search tool and schematic diagrams for Ig-antigen interactions are available for download in PDF format. The ultimate purpose of BEID is to enhance the understanding of the rules of engagement between antigen and the corresponding bound Ig molecules. It is also a precious data source for developing computational predictors for B-cell epitopes.
Tong
Joo Chuan
JC
Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore. jctong@i2r.a-star.edu.sg
Song
Chun Meng
CM
Tan
Paul Thiam Joo
PT
Ren
Ee Chee
EC
Sinha
Animesh A
AA