The failure of HIV vaccines: a new autovaccine may overcome some problems.
The hypothesis of an autovaccine for HIV is borne out by: (1) the present lack of a valid vaccine; (2) by a remarkable improvement of the HAART, which however does not prevent HIV mutagenicity and a consequent valid immunological response and (3) the persistence of a hidden infection ready to thrive again. The preparation of the autovaccine is described as well as the administration schedule but only a clinical study will define its validity.
Bocci
Velio
V
Department of Physiology, University of Siena, via Aldo Moro 2, Siena, Italy. bocci@unisi.it
Travagli
Valter
V
Zanardi
Iacopo
I
D016915:AIDS Vaccines / Q000096:biosynthesis* / Q000627:therapeutic use*; D054991:Autovaccines / Q000096:biosynthesis* / Q000627:therapeutic use*; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans
D016915:AIDS Vaccines; D054991:Autovaccines