title: [Preparation of Zhongjiefeng dispersible tablets].
abstract: OBJECTIVE
  To prepare Zhongjiefeng dispersible tablets.
  
  
  METHODS
  The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test.
  
  
  RESULTS
  The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins.
  
  
  CONCLUSIONS
  The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.
authors.affiliation: Institute of Materia Medica, Guangdong Pharmaceutical University/Guangdong Key Laboratory of Advanced Drug Delivery, Guangzhou 510006, China. zfwu527@163.com
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
mesh_terms: D002482:Cellulose / Q000008:administration & dosage / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000737:chemistry; D019684:Magnoliopsida / Q000737:chemistry*; D010592:Pharmaceutic Aids / Q000008:administration & dosage* / Q000737:chemistry / Q000145:classification; D010946:Plants, Medicinal / Q000737:chemistry; D011205:Povidone / Q000008:administration & dosage / Q000737:chemistry; D012995:Solubility; D013607:Tablets; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D010592:Pharmaceutic Aids; D013607:Tablets; D002482:Cellulose; D011205:Povidone