title: [Hairy cell leukemia in young patients].
abstract: OBJECTIVE
  To characterize clinical symptoms, course, immediate and long-term treatment results in young patients with hair cell leukemia (HCL).
  
  
  METHODS
  The data on 41 HCL patients were analysed. The diagnosis was made by standard diagnostic protocol for HCL detection.
  
  
  RESULTS
  The analysis of the age of 160 HCL patients studied demonstrated high (26%) incidence of HCL at young age. Young patients with HCL had special clinical manifestations and specific long-term outcomes of treatment with standard schemes.
  
  
  CONCLUSIONS
  Differences in occurrence of recurrences after standard therapy make it necessary to consider young HCL patients as a separate group who need adjuvant treatment to prolong remission.
authors.forename: L S
authors.initials: LS
authors.lastname: Al'-Radi
authors.forename: R S
authors.initials: RS
authors.lastname: Samoĭlova
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Tikhonova
authors.forename: O A
authors.initials: OA
authors.lastname: Diagileva
authors.forename: I N
authors.initials: IN
authors.lastname: Naumova
authors.forename: I B
authors.initials: IB
authors.lastname: Kaplanskaia
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Varlamova
mesh_terms: D000328:Adult; D000367:Age Factors; D015703:Antigens, CD / Q000276:immunology; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D017338:Cladribine / Q000008:administration & dosage / Q000627:therapeutic use; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007370:Interferon Type I / Q000008:administration & dosage / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology / Q000628:therapy*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D011994:Recombinant Proteins; D012737:Sex Factors; D013156:Splenectomy
chemical_list: D015703:Antigens, CD; D000970:Antineoplastic Agents; D007370:Interferon Type I; D011994:Recombinant Proteins; D017338:Cladribine