Synthesis of fused pyran-carbahexopyranoses as glycosidase inhibitors.
Synthesis of polyhydroxylated oxabicyclo[4,4,0]decanes, which constitute a new family of annulated carbasugars, has been accomplished in a stereoselective manner by employing readily available 1,2-anhydro-3,4,6-tri-O-benzyl-alpha-d-glycopyranoses.
Doddi
Venkata Ramana
VR
Department of Chemistry, Indian Institute of Technology Kanpur, 208 016, India.
Kancharla
Pavan K
PK
Reddy
Y Suman
YS
Kumar
Amit
A
Vankar
Yashwant D
YD
D054329:Carbasugars / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011714:Pyrans / Q000737:chemistry*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D054329:Carbasugars; D011714:Pyrans; D006026:Glycoside Hydrolases