title: Endometrial carcinoma with choriocarcinomatous differentiation: a case report and review of the literature.
abstract: BACKGROUND
  Choriocarcinomas unrelated to pregnancy, teratomas, or germ cell tumors have been found in the stomach, lungs, colon, esophagus, bladder, breast, renal pelvis and other sites.
  
  
  METHODS
  We present a case of a 58-year-old woman with endometrial carcinoma with choriocarcinomatous differentiation. She received surgery and chemotherapy for endometrial adenocarcinoma. However, a metastatic tumor of choriocarcinomatous element appeared at the vaginal cuff 9 months after surgery. Additional chemotherapy for choriocarcinoma resulted in a decrease in the serum hCG and the tumor regressed. Fifty months following surgery, she is alive without disease.
  
  
  CONCLUSIONS
  Treatment and follow-up must be performed not only for the adenocarcinoma element but also for the choriocarcinoma element in patients presenting with endometrial carcinoma with choriocarcinomatous differentiation.
authors.affiliation: Department of Pathology, Osaka Medical College, Takatsuki, Osaka, Japan. yamatakashi@mub.biglobe.ne.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mori
authors.forename: Masanori
authors.initials: M
authors.lastname: Kanemura
authors.forename: Masahide
authors.initials: M
authors.lastname: Ohmichi
authors.forename: Yuro
authors.initials: Y
authors.lastname: Shibayama
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D002822:Choriocarcinoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged