title: [Study advances on carcinogens and their metabolites in urine of smokers].
abstract: There may contain a great many carcinogens in cigarette smoke. Various carcinogens and their metabolites were quantified in urine of smokers, including trans, trans-muconic acid, S-phenylmercapturic acid, 4-(methylnitrosamino)-1-(3-pyridyl )-1-butanol and its glucuronides and so on. Quantification of carcinogens and their metabolites in urine of smokers could provide information on carcinogen exposure, which may be helpful to the research for mechanisms of carcinogen and in the exploitation of new harmless cigarettes. The study advances on carcinogens and their metabolites in urine of smokers were reviewed.
authors.affiliation: Cancer Institute, Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 31009, China. milkwort@tom.com
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Lina
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000111:Acetylcysteine / Q000031:analogs & derivatives* / Q000652:urine; D002273:Carcinogens / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D009602:Nitrosamines / Q000652:urine*; D011725:Pyridines / Q000652:urine*; D012907:Smoking / Q000652:urine*; D013011:Sorbic Acid / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D002273:Carcinogens; D009602:Nitrosamines; D011725:Pyridines; C005939:muconic acid; C053003:S-phenyl-N-acetylcysteine; C099565:4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol; D000111:Acetylcysteine; D013011:Sorbic Acid