title: A randomized trial of a lifestyle intervention in obese endometrial cancer survivors: quality of life outcomes and mediators of behavior change.
abstract: BACKGROUND
  To examine the effects of a 6 month lifestyle intervention on quality of life, depression, self-efficacy and eating behavior changes in overweight and obese endometrial cancer survivors.
  
  
  METHODS
  Early stage endometrial cancer survivors were randomized to intervention (n = 23) or usual care (n = 22) groups. Chi-square, Student's t-test and repeated measures analysis of variance were used in intent-to-treat analyses. Outcomes were also examined according to weight loss.
  
  
  RESULTS
  Morbidly obese patients had significantly lower self-efficacy, specifically when feeling physical discomfort. There was a significant improvement for self-efficacy related to social pressure (p = .03) and restraint (p = .02) in the LI group. There was a significant difference for emotional well-being quality of life (p = .02), self-efficacy related to negative emotions (p < .01), food availability (p = .03), and physical discomfort (p = .01) in women who lost weight as compared to women who gained weight. Improvement in restraint was also reported in women who lost weight (p < .01).
  
  
  CONCLUSIONS
  This pilot lifestyle intervention had no effect on quality of life or depression but did improve self-efficacy and some eating behaviors.
  
  
  BACKGROUND
  http://www.clinicaltrials.gov; NCT00420979.
authors.affiliation: University Hospitals Case Medical Center, Cleveland, OH, USA. vivian.vongruenigen@UHhospitals.org
authors.forename: Vivian E
authors.initials: VE
authors.lastname: von Gruenigen
authors.forename: Heidi E
authors.initials: HE
authors.lastname: Gibbons
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Kavanagh
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Janata
authors.forename: Edith
authors.initials: E
authors.lastname: Lerner
authors.forename: Kerry S
authors.initials: KS
authors.lastname: Courneya
mesh_terms: D003863:Depression / Q000150:complications; D016889:Endometrial Neoplasms / Q000150:complications* / Q000523:psychology; D005247:Feeding Behavior; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications / Q000523:psychology / Q000628:therapy*; D010865:Pilot Projects; D011788:Quality of Life / Q000523:psychology; D040242:Risk Reduction Behavior; D020377:Self Efficacy; D015430:Weight Gain; D015431:Weight Loss