The structural dynamics of macromolecular processes.
Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.
Russel
Daniel
D
Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158-2330, USA.
Lasker
Keren
K
Phillips
Jeremy
J
Schneidman-Duhovny
Dina
D
Velázquez-Muriel
Javier A
JA
Sali
Andrej
A
D002468:Cell Physiological Phenomena; D003198:Computer Simulation; D046911:Macromolecular Substances / Q000378:metabolism*; D008954:Models, Biological
D046911:Macromolecular Substances