title: Bloodstream infections in a German paediatric oncology unit: prolongation of inpatient treatment and additional costs.
abstract: In this matched cohort study, clinical data from 43 paediatric cancer patients with bloodstream infection (BSI) were compared with 43 thoroughly matched control patients without BSI. BSI led to a median additional length of inpatient treatment of 12 days (IQR 8.5-16 days; P<0.001), accounting for median additional expenses of euro4400 (IQR, euro3145-5920) per case [6.970 US Dollar (IQR 4.938-9.294)]. Thus, BSI substantially increased financial resources required for inpatient treatment. These data compiled from a paediatric cancer unit may be utilized to estimate the cost-benefit ratio of targeted preventive measures.
authors.affiliation: Department of Paediatric Hematology and Oncology, Children's Hospital, Medical Center, University of Bonn, Adenauerallee 119, 53113 Bonn, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Biwersi
authors.forename: Nico
authors.initials: N
authors.lastname: Hepping
authors.forename: Udo
authors.initials: U
authors.lastname: Bode
authors.forename: Gudrun
authors.initials: G
authors.lastname: Fleischhack
authors.forename: Anja
authors.initials: A
authors.lastname: von Renesse
authors.forename: Martin
authors.initials: M
authors.lastname: Exner
authors.forename: Steffen
authors.initials: S
authors.lastname: Engelhart
authors.forename: Beate
authors.initials: B
authors.lastname: Gieselmann
authors.forename: Arne
authors.initials: A
authors.lastname: Simon
mesh_terms: D000293:Adolescent; D016470:Bacteremia / Q000150:complications / Q000191:economics* / Q000382:microbiology; D002173:Cancer Care Facilities / Q000191:economics; D016022:Case-Control Studies; D055499:Catheter-Related Infections / Q000150:complications / Q000191:economics* / Q000382:microbiology; D002408:Catheters, Indwelling / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003365:Costs and Cost Analysis; D003428:Cross Infection / Q000150:complications / Q000191:economics* / Q000382:microbiology; D005260:Female; D005858:Germany; D006760:Hospitalization / Q000191:economics; D006776:Hospitals, Pediatric / Q000191:economics*; D006801:Humans; D007223:Infant; D007902:Length of Stay / Q000191:economics*; D008297:Male; D009369:Neoplasms / Q000150:complications*