[Advance in the research and discovery of novel drugs based on chemogenomics].
Chemogenomics/chemical genomics has been widely used in novel drug research and discovery. Firstly, the concept of chemogenomics was introduced briefly. Secondly, we reviewed the progress of novel drug research and discovery based on forward chemogenomics, reverse chemogenomics and predictive chemogenomics. Finally, we showed progress of the research that chemogenomics has been used to novel drug research and discovery in pharmaceuticals companies.
He
Bao-Kun
BK
Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China.
Ma
Zeng-Chun
ZC
Wang
Yu-Guang
YG
Gao
Yue
Y
D000818:Animals; D016503:Drug Delivery Systems; D055808:Drug Discovery / Q000379:methods*; D004345:Drug Industry / Q000639:trends; D023281:Genomics / Q000379:methods*; D006801:Humans; D010597:Pharmacogenetics / Q000379:methods*