Baculovirus genes affecting host function.
Baculoviruses are insect-specific viruses. These large DNA viruses encode many genes in addition to those required to replicate and build new virions. These auxiliary genes provide selective advantages to the virus for invading and infecting host insects. Eight of these genes, which help the virus overcome insect defenses against invasion, are discussed. These include genes whose products help the virus traverse physical or physiological barriers and those that overcome host immune defenses.
Thiem
Suzanne M
SM
Department of Entomology, Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48825, USA. smthiem@msu.edu
D000818:Animals; D016367:Baculoviridae / Q000235:genetics* / Q000502:physiology*; D005814:Genes, Viral; D006790:Host-Parasite Interactions / Q000235:genetics*; D007113:Immunity, Innate; D007313:Insecta / Q000276:immunology / Q000821:virology*; D014714:Vertebrates / Q000276:immunology / Q000821:virology