title: [Fucoidan: advances in the study of its anti-inflammatory and anti-oxidative effects].
abstract: Fucoidan is a natural polysaccharide extracted from brown seaweeds, with a wide variety of biological features, especially the anti-inflammatory and anti-oxidative effects. Studies indicated that the anti-inflammatory effect of fucoidan related to its capacity to interact with the selectin or scavenger receptor on the cell membrane. Fucoidan can also inhibit the synthesis and release of reactive oxygen species (ROS), as well as promote its clearance, showing the anti-oxidative activity.
authors.affiliation: Key Laboratory of Neurodegenerative Disorders of the Ministry of Education, Department of Physiology, Capital Medical University, Beijing 100069, China.
authors.forename: Yan-qiu
authors.initials: YQ
authors.lastname: Cui
authors.forename: Ding-zhen
authors.initials: DZ
authors.lastname: Luo
authors.forename: Xiao-min
authors.initials: XM
authors.lastname: Wang
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D011134:Polysaccharides / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D051116:Receptors, Scavenger / Q000378:metabolism; D012624:Seaweed / Q000737:chemistry*; D019087:Selectins / Q000378:metabolism
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D011134:Polysaccharides; D017382:Reactive Oxygen Species; D051116:Receptors, Scavenger; D019087:Selectins; C007789:fucoidan