Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE).
The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia.
Djurovic
Srdjan
S
Institute of Psychiatry, University of Oslo, Norway. srdjan.djurovic@medisin.uio.no
Le Hellard
Stephanie
S
Kähler
Anna K
AK
Jönsson
Erik G
EG
Agartz
Ingrid
I
Steen
Vidar M
VM
Hall
Håkan
H
Wang
August G
AG
Rasmussen
Henrik B
HB
Melle
Ingrid
I
Werge
Thomas
T
Andreassen
Ole A
OA
D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D005838:Genotype; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012537:Scandinavian and Nordic Countries; D012559:Schizophrenia / Q000235:genetics*
C496711:MCTP2 protein, human; D008565:Membrane Proteins