title: Comparison of the remineralizing effect of a sodium fluoride mouthrinse versus a sodium monofluorophosphate and calcium mouthrinse: an in vitro study.
abstract: OBJECTIVE
  The aim of this in vitro study was to compare the remineralizing effect of three rinses: (A) 0.17% sodium monofluorophosphate and 0.05% calcium glycerophosphate (220 ppm fluoride), (B) 0.05% sodium fluoride (220 ppm fluoride) and (C) control mouthrinse (without fluoride or calcium).
  
  
  METHODS
  Demineralized areas were created in 90 pieces of bovine enamel by submerging them in an acid solution (pH 4.4) for 48 hours. Part of the surface was painted with nail varnish to preserve the demineralized area, and the specimens were assigned at random to three groups. The specimens were stored in artificial saliva at pH 7 and 37 degrees C for 30 days. Twice daily they were immersed for 60 seconds in the respective mouthrinse. Following the experimental period, the specimens were bisected and examined by scanning electron microscopy.
  
  
  RESULTS
  The mean percentage of remineralization produced by the mouthrinses was as follows: (A) 54.08 (95% CI 46.37-61.78), (B) 38.43 (95% CI 30.89-45.98) and (C) 30.18 (95% CI 25.56-34.80). The differences between the three groups were statistically significant.
  
  
  CONCLUSIONS
  The results show that the fluoride and calcium mouthrinse has a significantly greater remineralizing capacity than the fluoride mouthrinse with the same fluoride ion concentration under the in vitro conditions of this study.
authors.affiliation: Department of Stomatology, University of Valencia, Valencia, Spain.
authors.forename: Miriam
authors.initials: M
authors.lastname: Puig-Silla
authors.forename: José-María
authors.initials: JM
authors.lastname: Montiel-Company
authors.forename: José-Manuel
authors.initials: JM
authors.lastname: Almerich-Silla
mesh_terms: D000818:Animals; D002327:Cariostatic Agents / Q000494:pharmacology*; D002417:Cattle; D003743:Dental Enamel / Q000187:drug effects*; D005459:Fluorides / Q000494:pharmacology*; D005994:Glycerophosphates / Q000494:pharmacology*; D009067:Mouthwashes / Q000494:pharmacology*; D010710:Phosphates / Q000494:pharmacology*; D012969:Sodium Fluoride / Q000494:pharmacology*; D014089:Tooth Remineralization
chemical_list: D002327:Cariostatic Agents; D005994:Glycerophosphates; D009067:Mouthwashes; D010710:Phosphates; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides