title: Image quality of 16-slice computed tomography coronary angiography in patients with complete left bundle branch block.
abstract: OBJECTIVE
  Noninvasive diagnosis of coronary artery disease in patients with left bundle branch block is challenging. Multislice computed tomography can be useful in this population; however, quality of images depends on the patterns of myocardial contractions. We investigated the influence of left bundle branch block on image quality of multislice computed tomography coronary angiography.
  
  
  METHODS
  Multislice computed tomography coronary angiography was performed in 30 patients with left bundle branch block and 30 patients without conduction disturbances. Image quality of each coronary segment was visually assessed and rated on a five-point scale (1=highest quality).
  
  
  RESULTS
  Average image quality score in the best cardiac cycle phase did not differ significantly between groups (1.71+/-0.59 in the left bundle branch block group vs. 1.60+/-0.57 in the control group, P=0.46). In the left bundle branch block group, a significantly lower image quality score was observed in end-systolic cardiac phase (2.67+/-0.6 vs. 2.22+/-0.65 in the control group, P=0.007), whereas no difference was demonstrated in mid-diastolic phase (1.73+/-0.6 vs. 1.69+/-0.66 in the control group, P=0.81). After image assessment in multiple cardiac phases, an increase in image quality score was higher in the left bundle branch block than in the control group (0.2+/-0.17 vs. 0.11+/-0.14, P=0.003). A negative correlation was observed between image quality score and both the heart rate and heart rate variability in both groups (P<0.001).
  
  
  CONCLUSIONS
  A nonsignificantly lower overall image quality of multislice computed tomography coronary angiography was demonstrated in the left bundle branch block group. In the presence of left bundle branch block, image quality in the end-systolic phase was significantly lower. Image assessment in multiple phases increased overall image quality and is therefore advisable in patients with left bundle branch block. Increased heart rate and heart rate variability worsened image quality in both groups.
authors.affiliation: Department of Radiology, Kaunas University of Medicine, Eiveniu 2, Kaunas, Lithuania. jankauskas.antanas@gmail.com
authors.forename: Antanas
authors.initials: A
authors.lastname: Jankauskas
authors.forename: Jurgita
authors.initials: J
authors.lastname: Zaveckiene
authors.forename: Gabija
authors.initials: G
authors.lastname: Pundziūte
authors.forename: Rimvydas
authors.initials: R
authors.lastname: Slapikas
authors.forename: Algidas
authors.initials: A
authors.lastname: Basevicius
authors.forename: Remigijus
authors.initials: R
authors.lastname: Zaliūnas
mesh_terms: D000368:Aged; D015992:Body Mass Index; D002037:Bundle-Branch Block / Q000150:complications / Q000000981:diagnostic imaging*; D016009:Chi-Square Distribution; D003287:Contrast Media; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000592:standards*
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide