title: No supplemental muscle relaxants are required during propofol and remifentanil total intravenous anesthesia for laparoscopic pelvic surgery.
abstract: BACKGROUND
  No administration of supplemental muscle relaxants may be beneficial to the recovery of the ambulatory laparoscopic surgery. For this study, we compared the cardiorespiratory factors during propofol and remifentanil anesthesia for laparoscopic pelvic surgery (LPS) with or without supplemental muscle relaxants.
  
  
  METHODS
  In total, 56 healthy female patients scheduled to undergo laparoscopic pelvic surgeries were randomly assigned to two groups (A and B). Anesthesia was induced with lidocaine 30 mg, propofol target organ concentration 5.0 microg/mL, remifentanil 3.0 ng/mL, and rocuronium 0.6 mg/kg intravenously (i.v.). After tracheal intubation, anesthesia was maintained with 2.0-5.0 microg/mL of propofol and 1-4 ng/mL of remifentanil i.v. All the patients' lungs were mechanically ventilated in both groups and intermittent bolus doses of rocuronium (0.15 mg/kg i.v.) were administered in group A-however, not in group B. Heart rate (HR) and systolic arterial pressure (SAP), diastolic arterial pressure (DAP), end-tidal carbon-dioxide concentration (EtCO(2)), peak inspiratory pressure (PIP), expired minute ventilation (MV), intra-abdominal pressure (IAP), and temperature were measured during the pneumoperitoneum.
  
  
  RESULTS
  There were no group differences in HR, SAP, DAP, EtCO(2), PIP, IAP, MV, PaO(2), PaCO(2), and temperature between groups A and B.
  
  
  CONCLUSIONS
  No supplemental muscle relaxants are required during propofol and remifentanil total i.v. anesthesia for LPS.
authors.affiliation: Department of Anesthesiology, Kyung Hee University, East-West Neo Medical Center, Seoul, Korea.
authors.forename: Cheol-Min
authors.initials: CM
authors.lastname: Paek
authors.forename: Jae-Woo
authors.initials: JW
authors.lastname: Yi
authors.forename: Bong-Jae
authors.initials: BJ
authors.lastname: Lee
authors.forename: Jong-Man
authors.initials: JM
authors.lastname: Kang
mesh_terms: D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000008:administration & dosage; D010388:Pelvis; D010880:Piperidines / Q000008:administration & dosage*; D011028:Pneumoperitoneum, Artificial; D015742:Propofol / Q000008:administration & dosage*; D000077208:Remifentanil; D012121:Respiration, Artificial; D016896:Treatment Outcome
chemical_list: D018686:Anesthetics, Intravenous; D009125:Muscle Relaxants, Central; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol