title: Terminal ileal atresia, total colonic aganglionosis, and thrombophilia.
abstract: Inherited thrombophilia, a predisposition for a hypercoagulable state, has been associated with cases of intestinal atresia. In this communication, we report a case of terminal ileal atresia and total colonic aganglionosis (Hirschsprung's disease), a rarely documented association, in a neonate who seemed to have a hypercoagulable state. The case stresses the need for recognition of this sequence of events in order to achieve optimal management.
authors.affiliation: Department of Pathology and Laboratory Medicine, Drexel University College of Medicine and St. Christopher's Hospital for Children, Philadelphia, PA, USA. J.deChadarevian@DrexelMed.edu
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: de Chadarévian
authors.forename: Shondell M
authors.initials: SM
authors.lastname: Bouie
authors.forename: Marie E
authors.initials: ME
authors.lastname: Peddinghaus
authors.forename: Lori R
authors.initials: LR
authors.lastname: Luck
authors.forename: Marshall Z
authors.initials: MZ
authors.lastname: Schwartz
authors.forename: Rajeev
authors.initials: R
authors.lastname: Prasad
authors.forename: Eric N
authors.initials: EN
authors.lastname: Faerber
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology*; D006627:Hirschsprung Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D007082:Ileum / Q000002:abnormalities*; D007223:Infant; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications* / Q000473:pathology; D008297:Male; D019851:Thrombophilia / Q000150:complications / Q000151:congenital* / Q000473:pathology