Activity-guided isolation of antioxidant principles from Limoniastrum feei (Girard) Batt.
Bioguided fractionation of a leaves extract from Limoniastrum feei (Girard) Batt. (Plumbaginaceae) led to the isolation of seven polyphenolic constituents: gallic acid (1), myrciaphenone A (2), myricetin-3-O-beta-galactopyranoside (3-1), epigallocatechin gallate (3-2), myricetin 3-O-alpha-rhamnopyranoside (4), quercetin (5) and myricetin (6). Gallic acid was the most antioxidant compound in DPPH [(0.94 +/- 0.68) microg/mL] and FRAP [(0.83 +/- 0.15) microM Fe2+/mL] tests, whereas myricetin was a more specific superoxide radical scavenger since it was the most active product in the superoxide nitroblue tetrazolium hypoxanthine/xanthine oxidase test [(1.86 +/- 0.12) microg/mL].
Chaabi
Mehdi
M
LC1 UMR-CNRS 7175, Biotechnologies, Biomolécules et Innovations Thérapeutiques, Faculté de Pharmacie de Strasbourg, 78 route du Rhin, 67401 Illkirch, France.
Beghidja
Noureddine
N
Benayache
Samir
S
Lobstein
Annelise
A
D000462:Algeria; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D002392:Catechin / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology; D005707:Gallic Acid / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010636:Phenols / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D029606:Plumbaginaceae / Q000737:chemistry*; D059808:Polyphenols
D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols; D059808:Polyphenols; D005707:Gallic Acid; D002392:Catechin; C045651:epigallocatechin gallate