Shape selectivity in embedded polar group stationary phases for liquid chromatography.
Seven columns with embedded polar functionality were evaluated for use in liquid chromatography with a focus on molecular shape recognition. Tests based on Standard Reference Material 869b Column Selectivity Test Mixture for Liquid Chromatography and the Tanaka test indicate that only two of the phases are slightly shape selective at 20 degrees C. The shape recognition characteristics of the phases appear to be directly related to the density of the embedded polar ligands and the temperature of the separation, consistent with trends observed with conventional hydrocarbon phases.
Rimmer
Catherine A
CA
Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8392, USA. catherine.rimmer@nist.gov
Sander
Lane C
LC