title: Anaemia and mineral bone disorder in chronic kidney disease: a review of the current literature and implications for clinical nursing practice.
abstract: Secondary hyperparathyroidism (SHPT) is one of the factors reported to have a negative impact on anaemia of chronic kidney disease (ACKD) and its treatment. SHPT is one of the abnormalities resulting from altered bone mineral metabolism. Five possible mechanisms have been proposed as to how SHPT impacts on anaemia in this paper. Each of these mechanisms will be considered and the treatment options reviewed including the implications for erythropoietic stimulating agents (ESA) prescribing. Anaemia and SHPT are both strongly predictive of complications and death from cardiovascular events in patients with chronic kidney disease (CKD). Nursing care of this group of patients should, therefore, be holistic in order to ensure optimum management. Ways in which we can practice to enhance quality of life and outcomes in this patient population will be discussed.
authors.affiliation: Oxford Kidney Unit, Churchill Hospital, Old Road Headington, Oxford OX3 7LJ, UK. claire.limrick@orh.nhs.uk
authors.forename: Claire
authors.initials: C
authors.lastname: Limrick
authors.forename: Coral
authors.initials: C
authors.lastname: McNichols-Thomas
mesh_terms: D000740:Anemia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D002117:Calcitriol / Q000172:deficiency; D002985:Clinical Protocols; D055317:Evidence-Based Practice; D006397:Hematinics / Q000627:therapeutic use; D006694:Holistic Health; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D009398:Nephrology; D024802:Nurse's Role; D010348:Patient Care Team / Q000458:organization & administration; D010353:Patient Education as Topic; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D006435:Renal Dialysis; D012307:Risk Factors; D012720:Severity of Illness Index; D017211:Treatment Failure
chemical_list: D006397:Hematinics; D002117:Calcitriol