Oral carcinoma epidemiology in Paraná State, Southern Brazil.
Oral carcinoma is the sixth most frequent type of cancer in the world and the seventh most common in Brazil (the country with the highest incidence in Latin America). Mean five-year survival remains one of the lowest among the main cancers, thus justifying studies that contribute to the development of preventive strategies. The aim of this study was to compare the epidemiological, clinical, and histological characteristics of 91 patients with oral carcinoma. Mean age was 58.62 +/- 10.46 years, and male-to-female ratio was 6.6:1.0 (79 men and 12 women). European descendants predominated with 79 patients (86.8%). Eighty-five individuals (93.4%) smoked and 70 (76.9%) consumed alcohol regularly. Anatomical distribution of tumors was: 27 (29.7%) tongue; 18 (19.8%) floor of mouth; 11 (12.1%) oropharynx; and 11 (12.1%) oral mucosa. Fifty-seven patients (62.6%) presented lymph node involvement and three (3.3%) had distant metastases. Surgery and radiotherapy were used in 43.2% of patients. With the exception of the male/female ratio (which was higher), our data are consistent with previous studies on oral carcinoma patients.
Losi-Guembarovski
Roberta
R
Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil. rolosi@uol.com.br
Menezes
Rodrigo Paes de
RP
Poliseli
Fernando
F
Chaves
Vivian Nappi
VN
Kuasne
Hellen
H
Leichsenring
Andrei
A
Maciel
Marcos Euzébio
ME
Guembarovski
Alda Losi
AL
Oliveira
Benedito W
BW
Ramos
Gyl
G
Mizuno
Lauro Toyshi
LT
Cavalli
Iglenir João
IJ
Ribeiro
Enilze Maria de Souza Fonseca
EM
Cólus
Ilce Mara de Syllos
IM
D001938:Brazil / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects