title: Magnetic resonance imaging in patients with meningitis induced hearing loss.
abstract: The aim of this multicentre study was to compare T1 with T2 weighted MRI scans of the labyrinth after meningitis and to investigate whether waiting with scanning improved the reliability of diagnosing an ongoing process such as cochlear osteogenesis. Forty-five patients were included who suffered from meningitis induced hearing loss (radiological imaging <1 year after meningitis). Twenty-one gadolinium enhanced T1 and 45 T2 weighted MRI scans were scored by two radiologists regarding the condition of the labyrinth. These radiological observations were compared with the condition of the cochlea as described during cochlear implantation. A higher percentage of agreement with surgery was found for T2 (both radiologists 73%) than for T1 weighted MRI scans (radiologist 1: 62%, radiologist 2: 67%), but this difference is not significant. There was no significant difference between early (0-3 months) and late (>3 months) scanning, showing that radiological imaging soon after meningitis allows early diagnosis without suffering from a lower agreement with surgical findings.
authors.affiliation: Department of Otorhinolaryngology, Radboud University Medical Centre, Nijmegen, The Netherlands. j.beijen@kno.umcn.nl
authors.forename: J
authors.initials: J
authors.lastname: Beijen
authors.forename: J
authors.initials: J
authors.lastname: Casselman
authors.forename: F
authors.initials: F
authors.lastname: Joosten
authors.forename: T
authors.initials: T
authors.lastname: Stover
authors.forename: A
authors.initials: A
authors.lastname: Aschendorff
authors.forename: A
authors.initials: A
authors.lastname: Zarowski
authors.forename: H
authors.initials: H
authors.lastname: Becker
authors.forename: E
authors.initials: E
authors.lastname: Mylanus
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000473:pathology; D019929:Cochlear Implantation / Q000379:methods; D003937:Diagnosis, Differential; D007758:Ear, Inner / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008581:Meningitis / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D015203:Reproducibility of Results; D055815:Young Adult