title: Therapeutic Difficulty in a Case of Supratentorial Primitive Neuroectodermal Tumor Diagnosed during Pregnancy.
abstract: We report a supratentorial primitive neuroectodermal tumor (sPNET) in 17-year-old primipara in the second trimester her pregnancy. Magnetic resonance imaging revealed a left frontoparietal mass with solid and cystic component. Gross-total resection was achieved via a left frontoparietal craniotomy. It was decided to suspend the radiotherapy and chemotherapy until the 30 weeks of gestation. But, a sudden uncal herniation was developed due to the reccurrence of the tumor and bleeding into the tumor at the 25 weeks of gestation and the patient died after urgent decompressive surgery. sPNETs is an extremely rare brain tumor in pregnancy and only two cases were reported in the literature to date. There is no universally agreed treatment protocol for sPNETs during pregnancy and a multidisciplinary approach is required in treatment. In the present study, the clinical, histopathological features and therapeutical difficulties of sPNETs diagnosed during pregnancy was discussed with the literature review.
authors.affiliation: Department of Neurosurgery, Baskent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Feyzi Birol
authors.initials: FB
authors.lastname: Sarica
authors.forename: Kadir
authors.initials: K
authors.lastname: Tufan
authors.forename: Orhan
authors.initials: O
authors.lastname: Sen
authors.forename: Bulent
authors.initials: B
authors.lastname: Erdogan