title: Postpartum Churg-Strauss syndrome with severe cardiac involvement: description of a case and review of the literature.
abstract: Churg-Strauss syndrome (CSS) is a rare small- or intermediate-vessel necrotizing vasculitis typically characterized by asthma, lung infiltrates, necrotizing granulomas, and hypereosinophilia. In this report, we describe the case of a 35-year-old woman who, during her third trimester of pregnancy, developed dyspnea and, after delivery, severe cardiac failure which required heart transplantation. Diagnosis of CSS was made after performing a myocardial biopsy. We have also undertaken a review of the English-language literature regarding previously reported cases of pregnancies in women suffering from Churg-Strauss syndrome with particular attention to those patients with cardiovascular involvement.
authors.affiliation: Department of Pathology and Laboratory Medicine, Section of Pathology, University of Parma, Via Gramsci 14, 43100, Parma, Italy. domenico.corradi@unipr.it
authors.forename: Domenico
authors.initials: D
authors.lastname: Corradi
authors.forename: Roberta
authors.initials: R
authors.lastname: Maestri
authors.forename: Fabio
authors.initials: F
authors.lastname: Facchetti
mesh_terms: D000328:Adult; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006333:Heart Failure / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D016027:Heart Transplantation; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis*