title: 99mTc-red blood cells SPECT and planar scintigraphy in the diagnosis of hepatic hemangiomas.
abstract: The aim of the study is the assessment of the value of SPECT (single photon emission computerized tomography) using 99mTc-labeled red blood cells in the detection of liver hemangioma, in comparison to planar imaging. With planar red blood cell scintigraphy, sensitivity of the method was 76%, specificity 98%, positive predictive value 98% and negative predictive value 79%. With SPECT, sensitivity of the method was 95%, specificity 98%, positive predictive value 98% and negative predictive value 94%. The smallest lesion detected by planar red blood cell scintigraphy was 1.2 cm, and with SPECT red blood cell scintigraphy 0.8 cm. The use of 99mTc-labeled red blood cells SPECT improved the sensitivity much more in smaller lesions (0.8 to 2 cm), than in bigger ones (2-5 cm). SPECT with radiolabeled red blood cells significantlyy improves the results of scintigraphic findings, especially in the small lesions.
authors.affiliation: Institute for Nuclear Medicine, Clinical Center of Serbia.
authors.forename: M V
authors.initials: MV
authors.lastname: Artiko
authors.forename: P D
authors.initials: PD
authors.lastname: Sobić-Saranović
authors.forename: S M
authors.initials: SM
authors.lastname: Perisić-Savić
authors.forename: V M
authors.initials: VM
authors.lastname: Stojković
authors.forename: B I
authors.initials: BI
authors.lastname: Radoman
authors.forename: S J
authors.initials: SJ
authors.lastname: Knezević
authors.forename: S N
authors.initials: SN
authors.lastname: Petrović
authors.forename: B V
authors.initials: BV
authors.lastname: Obradović
authors.forename: V
authors.initials: V
authors.lastname: Milović
mesh_terms: D000328:Adult; D004912:Erythrocytes; D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013670:Sodium Pertechnetate Tc 99m; D015899:Tomography, Emission-Computed, Single-Photon; D055815:Young Adult
chemical_list: D013670:Sodium Pertechnetate Tc 99m