title: Synthesis and antibacterial activity of DL-threo-1-(1-methylsulfonylpyrrole-3-yl)-2-difluoroacetamidopropane-1,3-diol.
abstract: The three-stage synthesis of a pyrrole analogue of chloramphenicol (5) was described. It is inactive.
authors.affiliation: Department of Organic Chemistry, Medical University, Mickiewicza 2A St., 15-230 Białystok, Poland. dkrajews@umwb.edu.pl
authors.forename: Dorota
authors.initials: D
authors.lastname: Krajewska
authors.forename: Krystyna
authors.initials: K
authors.lastname: Midura-Nowaczek
mesh_terms: D000081:Acetamides / Q000138:chemical synthesis / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002701:Chloramphenicol / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: C539167:1-(1-methylsulfonylpyrrol-3-yl)-2-difluoroacetamidopropane-1,3-diol; D000081:Acetamides; D000900:Anti-Bacterial Agents; D011758:Pyrroles; D002701:Chloramphenicol