title: [Diabetic foot infections. Prevalence and antibiotic sensitivity of the causative microorganisms].
abstract: BACKGROUND
  Foot infections are a common reason for hospitalization and a cause of complications in patients with diabetes. The aim of this study was to determine the prevalence of microorganisms found on culture in complicated diabetic foot infections in hospitalized patients, and the sensitivity of the causative microorganisms to antimicrobial agents.
  
  
  METHODS
  Between December 2001 and December 2005 in our department, 84 samples in 62 diabetic patients with moderate/severe infection were collected for microbiological study.
  
  
  RESULTS
  At least one microorganism was isolated in 88% of samples. The most frequently isolated germ group was gram-positive bacteria (55% of the samples), with Staphylococcus aureus (33%) in the first position, followed by Pseudomonas aeruginosa (12%), Enterococcus spp. (9%), and Escherichia coli (8%). Culture for anaerobic microorganisms was only performed in half the samples; 25% were positive, and Peptostreptococcus spp. predominated. Among the multiresistant microorganisms, methicillin-resistant staphylococci aureus (MRSA) were the most common, accounting for 38% of the isolated strains of S. aureus, ie, 12% of all samples. As to the gram-negative microorganisms, nearly 30% of E. coli strains were resistant to amoxicillin/clavulanic acid and ciprofloxacin.
  
  
  CONCLUSIONS
  Most of the cultures in our study were monomicrobial, with S. aureus being the most prevalent microorganism, followed by enterobacteria and P. aeruginosa. The main resistant microorganism in diabetic foot infections requiring hospitalization was methicillin-resistant golden staphylococcus, which was found in 12% of the series.
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital General Universitario José María Morales Meseguer, Murcia, España.
authors.forename: Diego de Alcalá
authors.initials: Dde A
authors.lastname: Martínez-Gómez
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Ramírez-Almagro
authors.forename: Alvaro
authors.initials: A
authors.lastname: Campillo-Soto
authors.forename: Germán
authors.initials: G
authors.lastname: Morales-Cuenca
authors.forename: Jorge
authors.initials: J
authors.lastname: Pagán-Ortiz
authors.forename: José Luis
authors.initials: JL
authors.lastname: Aguayo-Albasini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000563:Amebicides / Q000494:pharmacology / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001431:Bacteriological Techniques; D017719:Diabetic Foot / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000469:parasitology; D004351:Drug Resistance; D024901:Drug Resistance, Multiple, Bacterial; D004747:Entamoeba / Q000187:drug effects / Q000302:isolation & purification; D004749:Entamoebiasis / Q000188:drug therapy / Q000209:etiology / Q000469:parasitology; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D013030:Spain / Q000453:epidemiology; D013045:Species Specificity; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology
chemical_list: D000563:Amebicides; D000900:Anti-Bacterial Agents