title: Solitary angiokeratoma of the tonsillar pillar of the oral cavity.
abstract: Solitary angiokeratoma has rarely been described in oral mucosa, mainly in the tongue, where the main concern is either aesthetical or due to bleeding problems. We present a case of solitary angiokeratoma of the tonsillar pillar in a 68-year-old man. Histologically, the morphology was typical of angiokeratoma. It showed an immunohistochemical pattern in consonance with a blood vessel origin, with expression of CD31, CD34, and von Willebrand factor. The lesion did not express D2-40. No other malformation or metabolic disorder was found in the patient. The lesion was surgically removed and due to the disproportionate post-surgery bleeding, the patient was studied by the Hematology Service, and she was diagnosed as an inhibitor of Factor VIII carrier.
authors.affiliation: Service of Anatomic Pathology, Hospital El Bierzo, Spain. gpyauflowerlion@terra.es
authors.forename: A
authors.initials: A
authors.lastname: Fernandez-Flores
authors.forename: J
authors.initials: J
authors.lastname: Sanroman
mesh_terms: D000368:Aged; D000794:Angiokeratoma / Q000473:pathology*; D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D014067:Tonsillar Neoplasms / Q000473:pathology*
chemical_list: D015703:Antigens, CD; D018952:Antigens, CD34; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D005169:Factor VIII