Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene.
A catalytic amount of 1,2-bis(diphenylphosphino)benzene (DPPBz) achieves selective cleavage of sp(3)-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to polyfluorinated aromatic compounds.
Hatakeyama
Takuji
T
International Research Center for Elements Science (IRCELS), Institute for Chemical Research, Uji, Kyoto 611-0011, Japan.
Kondo
Yoshiyuki
Y
Fujiwara
Yu-Ichi
Y
Takaya
Hikaru
H
Ito
Shingo
S
Nakamura
Eiichi
E
Nakamura
Masaharu
M
D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry*; D013053:Spectrophotometry
C519449:1,2-bis(diphenylphosphino)benzene; D001555:Benzene Derivatives; D063065:Organophosphonates; D007501:Iron