title: Changes of airway obstruction parameters in healthy children caused by mother's smoking during pregnancy.
abstract: The present study was aimed at the assessment of the impact of mother smoking during pregnancy on changes of phase angle (phi) and T(me)/T(E) index in healthy children. A hundred and twenty seven children, divided according to age (<6 months and >6 months of age) and mother smoking anamnesis were investigated by noncalibrated respiratory inductive plethysmography in the supine position. We found statistically significant changes of phi (p<0.05) and T(me)/T(E) in healthy children of non-smoking mothers against a group of smoking mother's children of up to 6 months of age. These differences were not confirmed in children older than 6 months. Moreover, in the smoking mother group, we found statistically significant changes (P<0.05) of phi and T(me)/T(E) in children of up to 6 months of age in comparison with children older than 6 month. The results revealed a negative impact of mother smoking during pregnancy represented by changes in airway obstruction parameters, which appeared especially in the group of youngest children.
authors.affiliation: Pediatric Clinic, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia. slavonosal@yahoo.com.
authors.forename: S
authors.initials: S
authors.lastname: Nosal
authors.forename: P
authors.initials: P
authors.lastname: Durdik
authors.forename: M
authors.initials: M
authors.lastname: Sutovska
authors.forename: S
authors.initials: S
authors.lastname: Franova
authors.forename: V
authors.initials: V
authors.lastname: Nosal
authors.forename: J
authors.initials: J
authors.lastname: Koppl
authors.forename: J
authors.initials: J
authors.lastname: Hamzik
authors.forename: P
authors.initials: P
authors.lastname: Banovcin
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010991:Plethysmography; D011247:Pregnancy; D012129:Respiratory Function Tests; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology*; D055815:Young Adult