[Pruritic urticarial papules and plaques of pregnancy].
OBJECTIVE
To define clinical presentation and therapy of pruritic urticarial apapules and plaques of pregnancy (PUPPP).


METHODS
20 women between 21 and 34 years of age were included in the present investigation. 16 were primipara and four--multipara. Fifteen of the patients had one fetus and five--bigemini.


RESULTS
In all cases both rash and pruritus had developed in the third trimester. In five cases there were historic data for pruritus in the end of the pregnancy in the patients' mother. In all cases there were striae of pregnancy, papules and plaques in the abdominal area, in 12 on the extremities and in five cases on face. All cases ended with deliveries of healthy newborns, without other complications of pregnancy, delivery or puerperium.


CONCLUSIONS
PUPPP is the most frequent pruritic dermatosis of pregnancy. Our data supports statement, that PUPPP are more frequent in third trimester, in primipara and bigemini. The papules and plaques are in the abdominal area and extremities and pruritus always present.
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000982:Antipruritics / Q000627:therapeutic use; D001623:Betamethasone / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D006919:Hydroxyzine / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000503:physiopathology*; D011263:Pregnancy Trimester, Third; D011537:Pruritus / Q000150:complications* / Q000188:drug therapy; D014581:Urticaria / Q000150:complications* / Q000188:drug therapy; D055815:Young Adult
D000893:Anti-Inflammatory Agents; D000982:Antipruritics; D006919:Hydroxyzine; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D006854:Hydrocortisone