title: Prevalence of nocturnal oxygen desaturation and self-reported sleep-disordered breathing in glaucoma.
abstract: OBJECTIVE
  To evaluate the prevalence of nocturnal oxygen desaturation and sleep-disordered breathing symptoms within a glaucoma population.
  
  
  METHODS
  One hundred and twelve subjects (glaucoma=52, control=60) aged between 45 and 80 years were recruited for the study. Clinical assessment included overnight ambulatory pulse oximetry monitoring and administration of a self-reported sleep-disordered breathing questionnaire.
  
  
  RESULTS
  There were no differences in age, sex, body mass index, or prevalence of systemic hypertension between the groups. The mean oxygen desaturation index of the glaucoma group (8.6) did not differ significantly from that of the control group (9.6) (P=0.715). The prevalence of moderate to severe respiratory dysfunction (oxygen desaturation index >20) in the glaucoma group (17%) was similar to that in the control group (12%) (P=0.463). The severity of sleep-disordered breathing symptoms was similar between the groups (P=0.157).
  
  
  CONCLUSIONS
  No statistically significant association was found between glaucoma and either nocturnal oxygen desaturation or sleep-disordered breathing. Although this study cannot exclude the possibility of either impaired optic nerve head autoregulation or hypoxic damage occurring secondary to sleep apnea syndrome, the findings do not support the routine use of pulse oximetry in the workup of individuals with glaucoma.
authors.affiliation: Department of Ophthalmology, Royal North Shore Hospital, Australia. tim.roberts@vgaustralia.com
authors.forename: Timothy V
authors.initials: TV
authors.lastname: Roberts
authors.forename: Chris
authors.initials: C
authors.lastname: Hodge
authors.forename: Stuart L
authors.initials: SL
authors.lastname: Graham
authors.forename: George
authors.initials: G
authors.lastname: Burlutsky
authors.forename: Paul
authors.initials: P
authors.lastname: Mitchell
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000453:epidemiology / Q000378:metabolism*; D006801:Humans; D000860:Hypoxia / Q000453:epidemiology / Q000378:metabolism*; D008297:Male; D010092:Oximetry; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000453:epidemiology / Q000378:metabolism*; D011795:Surveys and Questionnaires
chemical_list: D010100:Oxygen