title: Behaviour of nonresorbable bioactive glass-ceramic implanted into long bone defects: comparison with cancellous allografts.
abstract: BACKGROUND
  The goal of this retrospective study was to compare the long-term results after implantation of the nonresorbable glass-ceramic material and transplantation of the cancellous allografts into the defects of long bones.
  
  
  METHODS
  The bone cysts were excochleated and filled using granules of glass-ceramic material or cancellous allografts. Clinical, radiographic and scintigraphic examinations of 30 patients were carried out 2-14 years after their surgery.
  
  
  RESULTS
  Though signs of complete incorporation allowing full weight-bearing capacity were observed on plain radiographs, we detected pain in six out of nine patients after diaphyseal implantation of nonresorbable glass-ceramic. We found an increase in (99) (m)Tc-methylene diphosphonate uptake on the delayed images in the area of glass-ceramic implantation, mainly in its diaphyseal location. In patients after bone transplantation, the cancellous allografts were completely integrated and the scintigraphic findings were physiological.
  
  
  CONCLUSIONS
  The implantation of the nonresorbable glass-ceramic material into the diaphyseal defects of long bones is not suitable based on our study.
authors.affiliation: Department of Orthopaedic Surgery, Charles University, University Hospital, 500 05 Hradec Králové, Czech Republic. sponer.p@seznam.cz
authors.forename: Pavel
authors.initials: P
authors.lastname: Sponer
authors.forename: Karel
authors.initials: K
authors.lastname: Urban
authors.forename: Elen
authors.initials: E
authors.lastname: Urbanová
authors.forename: Karel
authors.initials: K
authors.lastname: Karpas
authors.forename: Pradeep George
authors.initials: PG
authors.lastname: Mathew
mesh_terms: D000293:Adolescent; D001672:Biocompatible Materials; D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000601:surgery*; D018786:Bone Substitutes; D002516:Ceramics; D002648:Child; D005260:Female; D005898:Glass; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes