title: [Association of insulinase gene polymorphisms with type 2 diabetes mellitus in patients from the Moscow population].
abstract: Association of 13 single nucleotide polymorphisms (SNPs) of insulinase (IDE) gene with type 2 diabetes mellitus (T2D) in the Moscow population has been examined. Three polymorphic markers (rs7078413, rs7899603, and rs551266) associated with the risk of T2D development have been revealed. Allele and genotype frequency distribution for these three markers differed significantly only in the sample of females between T2D patients and control individuals, while only in case of rs7078413 SNP genotype frequencies varied significantly in the total population.
authors.forename: P A
authors.initials: PA
authors.lastname: Slominskiĭ
authors.forename: O V
authors.initials: OV
authors.lastname: Pivovarova
authors.forename: M I
authors.initials: MI
authors.lastname: Shadrina
authors.forename: A V
authors.initials: AV
authors.lastname: Artem'eva
authors.forename: F G
authors.initials: FG
authors.lastname: Pfaipffer
authors.forename: N N
authors.initials: NN
authors.lastname: Rudovich
authors.forename: S E
authors.initials: SE
authors.lastname: Agadzhanian
authors.forename: V S
authors.initials: VS
authors.lastname: Pronin
authors.forename: S A
authors.initials: SA
authors.lastname: Limborskaia
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007339:Insulysin / Q000235:genetics*; D008297:Male; D009031:Moscow; D020641:Polymorphism, Single Nucleotide
chemical_list: D007339:Insulysin