title: A new presentation and exploration of human cerebral vasculature correlated with surface and sectional neuroanatomy.
abstract: The increasing complexity of human body models enabled by advances in diagnostic imaging, computing, and growing knowledge calls for the development of a new generation of systems for intelligent exploration of these models. Here, we introduce a novel paradigm for the exploration of digital body models illustrating cerebral vasculature. It enables dynamic scene compositing, real-time interaction combined with animation, correlation of 3D models with sectional images, quantification as well as 3D manipulation-independent labeling and knowledge-related meta labeling (with name, diameter, description, variants, and references). This novel exploration is incorporated into a 3D atlas of cerebral vasculature with arteries and veins along with the surrounding surface and sectional neuroanatomy derived from 3.0 Tesla scans. This exploration paradigm is useful in medical education, training, research, and clinical applications. It enables development of new generation systems for rapid and intelligent exploration of complicated digital body models in real time with dynamic scene compositing from highly parcellated 3D models, continuous navigation, and manipulation-independent labeling with multiple features.
authors.affiliation: Biomedical Imaging Lab, Singapore Bioimaging Consortium, Agency for Science, Technology and Research, 30 Biopolis Street, #07-01 Matrix, Singapore. wieslaw@sbic.a-star.edu.sg
authors.forename: Wieslaw L
authors.initials: WL
authors.lastname: Nowinski
authors.forename: Arumugam
authors.initials: A
authors.lastname: Thirunavuukarasuu
authors.forename: Ihar
authors.initials: I
authors.lastname: Volkau
authors.forename: Yevgen
authors.initials: Y
authors.lastname: Marchenko
authors.forename: Bivi
authors.initials: B
authors.lastname: Aminah
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gelas
authors.forename: Su
authors.initials: S
authors.lastname: Huang
authors.forename: Looi Chow
authors.initials: LC
authors.lastname: Lee
authors.forename: Jimin
authors.initials: J
authors.lastname: Liu
authors.forename: Ting Ting
authors.initials: TT
authors.lastname: Ng
authors.forename: Natalia G
authors.initials: NG
authors.lastname: Nowinska
authors.forename: Guoyu Yu
authors.initials: GY
authors.lastname: Qian
authors.forename: Fiftarina
authors.initials: F
authors.lastname: Puspitasari
authors.forename: Val M
authors.initials: VM
authors.lastname: Runge
mesh_terms: D000715:Anatomy / Q000379:methods*; D001921:Brain / Q000098:blood supply*; D002536:Cerebral Arteries / Q000033:anatomy & histology; D002550:Cerebral Veins / Q000033:anatomy & histology; D003196:Computer Graphics; D003198:Computer Simulation; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D009445:Neuroanatomy / Q000379:methods*