Surveillance cultures for detection of methicillin-resistant Staphylococcus aureus: diagnostic yield of anatomic sites and comparison of provider- and patient-collected samples.
We studied provider- and patient-collected samples from multiple anatomic sites to determine the yield for detection of methicillin-resistant Staphylococcus aureus (MRSA). Sampling of multiple sites was required to achieve a sensitivity of more than 90% for MRSA colonization. Groin and perineum samples yielded positive results significantly more often for community-onset MRSA than for hospital-onset MRSA. Agreement rates between provider- and patient-collected swab specimens were excellent.
Lautenbach
Ebbing
E
Division of Infectious Diseases of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6021, USA. ebbing@mail.med.upenn.edu
Nachamkin
Irving
I
Hu
Baofeng
B
Fishman
Neil O
NO
Tolomeo
Pam
P
Prasad
Priya
P
Bilker
Warren B
WB
Zaoutis
Theoklis E
TE
D000293:Adolescent; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001365:Axilla / Q000382:microbiology; D002648:Child; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D003430:Cross-Sectional Studies; D003470:Culture Media; D005260:Female; D006119:Groin / Q000382:microbiology; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D008875:Middle Aged; D009666:Nose / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D011159:Population Surveillance / Q000379:methods*; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology
D000900:Anti-Bacterial Agents; D003470:Culture Media