Seevolution: visualizing chromosome evolution.
CONCLUSIONS
Genome evolution underpins all of biology, yet its principles can be difficult to communicate to the non-specialist. To facilitate broader understanding of genome evolution, we have designed an interactive 3D environment that enables visualization of diverse genome evolution processes. The system can intuitively and interactively animate mutation histories involving genome rearrangement, point mutation, recombination, insertion and deletion. Multiple organisms related by a phylogeny can be visualized simultaneously. As methods to infer evolutionary histories of genomes become increasingly complex, visualization of the evolutionary process will not only be useful for communication, but will also serve as an exploratory tool for discovering new patterns of genome evolution.


BACKGROUND
The software is licensed under the GNU GPL and available for download from http://seevolution.org.
Esteban-Marcos
Andrés
A
Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia.
Darling
Aaron E
AE
Ragan
Mark A
MA
D002875:Chromosomes / Q000235:genetics*; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D019143:Evolution, Molecular; D016678:Genome; D012984:Software; D014584:User-Computer Interface