[Anti-Müllerian hormone--its role in management of involuntary infertility].
BACKGROUND
Although fertility in women decreases significantly after the age of 35 years, women in Norway - as in many other developed countries- postpone having children. It has long been recognised that there is a need for a better marker of ovarian function. This article provides an overview of physiological development of follicles in the ovaries and the special place Anti-Müllerian- hormone has in this process.


METHODS
Literature was retrieved from the databases PubMed, Athens and Embase by using the keywords Anti-Müllerian hormone, follicle, ovarian reserve, ovarian response and fertility. The reference lists of relevant articles were searched for additional information.


CONCLUSIONS
32 articles with relevant information were retrieved. The level of Anti-Müllerian hormone is relatively stable throughout the menstruation cycle. The hormone appears to be a reliable marker for ovarian reserve and ovarian response after controlled ovarian hyperstimulation during in vitro fertilisation. Determination of the hormone level will enable identification of women with high risk of deviating response upon ovarian hyperstimulation.
Kalra
Gurpreet Singh
GS
Department of Obstetrics and Gynaecology St. Michael's Hospital Southwell Street Bristol. gsk@doctors.org.uk
D054304:Anti-Mullerian Hormone / Q000096:biosynthesis / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000175:diagnosis / Q000628:therapy*; D007315:Insemination, Artificial / Q000009:adverse effects; D006080:Ovarian Follicle / Q000378:metabolism / Q000502:physiology; D016471:Ovarian Hyperstimulation Syndrome / Q000209:etiology; D010062:Ovulation Induction; D012307:Risk Factors
D015415:Biomarkers; D054304:Anti-Mullerian Hormone