title: [Prosthetic mechanic valve thrombosis in pregnant women: a report of two cases].
abstract: Patients with prosthetic mechanical heart valves should always be on prophylactic anticoagulation therapy for thromboembolic events. As pregnancy represents a high-risk period for thrombosis, those with mechanical heart valves should be accorded greater importance. We presented two pregnant patients with prosthetic mechanical mitral valves, who developed mechanical valve thrombosis while on fractionated and unfractionated heparin treatment, respectively. One patient received intensive anticoagulation treatment, and the other underwent redo valve replacement. Both patients were free of symptoms.
authors.affiliation: Erciyes Universitesi Tip Fakültesi, Kardiyoloji Anabilim Dali, Kayseri, Turkey. mtinanc@msn.com
authors.forename: Mehmet Tuğrul
authors.initials: MT
authors.lastname: Inanç
authors.forename: Orhan
authors.initials: O
authors.lastname: Doğdu
authors.forename: Mehmet Güngör
authors.initials: MG
authors.lastname: Kaya
authors.forename: Ali
authors.initials: A
authors.lastname: Doğan
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008943:Mitral Valve; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D012086:Reoperation; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D000925:Anticoagulants; D006493:Heparin