title: [A case of recurrence after curative total gastrectomy for gastric cancer successfully treated by combination chemotherapy with CPT-11 and CDDP].
abstract: A male in his sixties underwent total gastrectomy for gastric cancer in August, 2002. After surgery, he underwent 4 courses of adjuvant chemotherapy with S-1. About 2 years after the surgery, PET-CT detected liver metastasis and lymph node metastasis, so treatment with CPT-11+CDDP was started with the following regimen: 60 mg/m2 CPT-11 and 30 mg/m2 CDDP biweekly. Five months later, PET-CT revealed that the liver metastasis and lymph node metastasis had disappeared. After judgment of complete response(CR), we continued that treatment every four weeks for one year and every eight weeks for another one year. The patient was followed without any recurrence in January, 2007. For this case, PET-CT was effective for planning the treatment and assessing its response.
authors.affiliation: Dept. of Surgery, Yamagata Saisei Hospital.
authors.forename: Hiroto
authors.initials: H
authors.lastname: Fujimoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Urayama
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Kawaguchi
authors.forename: Keiji
authors.initials: K
authors.lastname: Ohta
authors.forename: Nobuo
authors.initials: N
authors.lastname: Seo
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D012008:Recurrence; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin