title: Fe(ClO4)3 x 6H2O: a mild and efficient catalyst for one-pot three component synthesis of beta-acetamido carbonyl compounds under solvent-free conditions.
abstract: A one-pot multi-component reaction for the synthesis of beta-acetamido carbonyl compounds is reported. The reaction uses a variety of aldehydes, acetophenone derivatives or methyl acetoacetate, acetonitrile, and acetyl chloride in the presence of ferric perchlorate, a mild, efficient and inexpensive catalyst effective under solvent free conditions.
authors.affiliation: Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran. mmh1331@yahoo.com
authors.forename: Majid M
authors.initials: MM
authors.lastname: Heravi
authors.forename: Farahnaz K
authors.initials: FK
authors.lastname: Behbahani
authors.forename: Mansoureh
authors.initials: M
authors.lastname: Daraie
authors.forename: Hossein A
authors.initials: HA
authors.lastname: Oskooie
mesh_terms: D000081:Acetamides / Q000737:chemistry; D000097:Acetonitriles / Q000737:chemistry; D000098:Acetophenones / Q000737:chemistry; D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D001547:Benzaldehydes / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D010472:Perchlorates / Q000737:chemistry*
chemical_list: D000081:Acetamides; D000097:Acetonitriles; D000098:Acetophenones; D000447:Aldehydes; D001547:Benzaldehydes; D004952:Esters; D005290:Ferric Compounds; D007659:Ketones; D010472:Perchlorates; C001473:iron perchlorate; C038699:acetophenone; C032175:benzaldehyde; C032159:acetonitrile