title: Effects of taurine administration on exercise.
abstract: Taurine concentration in rat skeletal muscles after endurance running, with and without taurine administration was studied. Taurine concentrations in skeletal muscles was significantly decreased in exercised groups without taurine administration. However, taurine administration reduced the decrease of taurine concentration in skeletal muscles in exercise. Oral administration of taurine has effect for maintaining taurine concentration in skeletal muscles in exercise. The duration of running time to exhaustion of rats, with and without taurine administration were studied. The duration of running time to exhaustion was significantly increased by taurine administration. Oral administration of taurine increases the ability of physical endurance. Rat urinary excretions of creatinine, creatine, 3-methylhistidine (3-MH) after treadmill running, with and without taurine administration were studied. Rat urinary excretions of creatinine, creatine, 3-MH after treadmill running was significantly decreased with taurine administration. Taurine administration was considered to reduce the exercise-induced muscle fatigue.
authors.affiliation: Department of Orthopaedic Surgery, Moriya Daiichi Hospital, Japan. yatabe@moriya.daiichi.or.jp
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Yatabe
authors.forename: Shumpei
authors.initials: S
authors.lastname: Miyakawa
authors.forename: Hajime
authors.initials: H
authors.lastname: Ohmori
authors.forename: Hajime
authors.initials: H
authors.lastname: Mishima
authors.forename: Takako
authors.initials: T
authors.lastname: Adachi
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003404:Creatinine / Q000652:urine; D006801:Humans; D008297:Male; D018763:Muscle Fatigue / Q000187:drug effects; D010805:Physical Conditioning, Animal; D051381:Rats; D017207:Rats, Sprague-Dawley; D013654:Taurine / Q000008:administration & dosage* / Q000494:pharmacology
chemical_list: D013654:Taurine; D003404:Creatinine