[Selective progesterone receptor modulators: future clinical applications].
Progesterone antagonists belong to the family of selective progesterone receptor modulators. SPRMs already have several applications in women's health. Their main value lies in their effect on endometrium. For example, they can be used to reduce tumor volume and uterine bleeding before uterine myoma surgery. They are also being evaluated for the treatment of endometriosis, and for estrogen-free contraception.
Bouchard
Philippe
P
Endocrinologie, Hôpital Saint Antoine, 184 rue du Faubourg Saint Antoine--75012 Paris.
Ouzounian
Sophie
S
Chabbert-Buffet
Nathalie
N
D001943:Breast Neoplasms / Q000188:drug therapy; D004715:Endometriosis / Q000188:drug therapy; D005260:Female; D006727:Hormone Antagonists / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy; D015394:Molecular Structure; D011980:Receptors, Progesterone / Q000187:drug effects*; D014594:Uterine Neoplasms / Q000188:drug therapy
D006727:Hormone Antagonists; D011980:Receptors, Progesterone