Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia?
Scammell
Thomas E
TE
Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, El CLS-705, Boston, MA 02215, USA. tscammel@bidmc.harvard.edu
Mochizuki
Takatoshi
T
D001921:Brain / Q000503:physiopathology; D002385:Cataplexy / Q000134:cerebrospinal fluid; D006970:Disorders of Excessive Somnolence / Q000134:cerebrospinal fluid*; D006632:Histamine / Q000134:cerebrospinal fluid* / Q000172:deficiency*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000134:cerebrospinal fluid* / Q000172:deficiency*; D009290:Narcolepsy / Q000134:cerebrospinal fluid*; D009479:Neuropeptides / Q000134:cerebrospinal fluid* / Q000172:deficiency*; D000068797:Orexins; D015398:Signal Transduction / Q000502:physiology; D014851:Wakefulness / Q000502:physiology
D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D000068797:Orexins; D006632:Histamine