title: [The density of prostate specific antigen of the transition zone as an early predictor of prostate cancer].
abstract: The investigation included 98 patients with the level of prostate specific antigen (PSA) of blood serum from 0 to 10 ng/ml and with the diagnosis confirmed by the systemic 12-points prostate biopsy. The data obtained clearly show that the PSA density of the transition zone is a potentially true predictor for the early prostate cancer diagnosis in patients with low and middle PSA level (from 0 to 10 ng/ml). When the threshold level of the PSE density in the transition zone is 0.35 ng/ml/cc, its sensitivity and specificity are higher than these indices for the PSA density.
authors.forename: M E
authors.initials: ME
authors.lastname: Topuzov
authors.forename: A E
authors.initials: AE
authors.lastname: Prialukhin
authors.forename: A V
authors.initials: AV
authors.lastname: Zhivov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Plekhanov
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D001706:Biopsy; D018450:Disease Progression; D006801:Humans; D008297:Male; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen