title: Immunosuppressive therapy for canine immune-mediated hemolytic anemia.
abstract: The mortality for dogs with severe immune-mediated hemolytic anemia (IMHA) is unacceptably high, and better immunosuppressive regimens are needed to increase survival. Understanding the basic immunology of the disease and the mechanisms of action of the available immunosuppressive therapies will help clinicians choose an appropriate immunosuppressive protocol. Prospective, randomized clinical studies must be conducted to evaluate the efficacy and safety of different combined immunosuppressive modalities to treat canine IMHA and improve patients' outcomes.
authors.affiliation: NYC Veterinary Specialists, Forest Hills, New York, USA.
authors.forename: Suliman
authors.initials: S
authors.lastname: Al-Ghazlat
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000188:drug therapy / Q000276:immunology / Q000401:mortality / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000188:drug therapy* / Q000276:immunology / Q000401:mortality; D004285:Dogs; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic / Q000662:veterinary; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents