Bisphosphonate osteonecrosis: a protocol for surgical management.
We present a protocol for the management of a subgroup of patients with bisphosphonate osteonecrosis who presented with painful, exposed, necrotic, alveolar bone. It is simple and can easily be adapted to suit anatomical variations of the oral cavity. Current guidelines based on consensus for the management of bisphosphonate-induced osteonecrosis fail to provide mucosal coverage, which is a primary requirement in managing the condition. We have evaluated the results of a group of 15 patients and analysed their postoperative progress for 24 months.
Markose
George
G
Department of Oral & Maxillofacial Surgery, Crosshouse Hospital, Kilmarnock, Ayrshire, UK. gmarkose@gmail.com
Mackenzie
Fiona R
FR
Currie
W J R
WJ
Hislop
W S
WS
D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008336:Mandibular Diseases / Q000139:chemically induced / Q000601:surgery; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D014081:Tooth Extraction; D016896:Treatment Outcome
D050071:Bone Density Conservation Agents; D004164:Diphosphonates