title: Expanding the application of a standardized questionnaire on recurrent wheezing in infancy.
abstract: OBJECTIVE
  To verify the possibility of extending the application of an instrument to investigate the prevalence and clinical characteristics of wheezing in infants.
  
  
  METHODS
  A cross-sectional study conducted as part of the International Study on Wheezing in Infants (EISL, Estudio Internacional de Sibilancias en Lactantes). A questionnaire was administered to parents of infants aged 12 to 15 months (group I) and 16 to 24 months (group II) infants.
  
  
  RESULTS
  One thousand, three hundred and sixty-four infants (45.4%) in group I and 250 (46.7%) in group II had had at least one episode (p = 0.58). The numbers of patients on inhaled beta(2)-agonists, inhaled or oral steroids and/or leukotriene modifiers were similar in both groups (p = 0.52, 0.12, 0.06, and 0.75). There were no differences between the groups in terms of night-time symptoms, shortness of breath, emergency room visits, asthma hospitalization or asthma diagnosed by a doctor (p = 0.09, 0.28, 0.54, and 0.45).
  
  
  CONCLUSIONS
  The application of the questionnaire can be extended to include infants up to 24 months of age.
authors.affiliation: h.chong@uol.com.brMedicina Interna, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Herberto José
authors.initials: HJ
authors.lastname: Chong Neto
authors.forename: Nelson Augusto
authors.initials: NA
authors.lastname: Rosário
mesh_terms: D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010290:Parents; D015995:Prevalence; D012008:Recurrence; D012135:Respiratory Sounds / Q000175:diagnosis* / Q000187:drug effects; D011795:Surveys and Questionnaires