An unusual presentation of Ehlers-Danlos syndrome vascular type with deep vein thrombosis: a case for multidisciplinary management.
Ehlers-Danlos syndrome (EDS) vascular type typically presents with significant vascular complications such as rupture of blood vessels, gravid uterus, or intestinal perforation. We report on a 24-year-old female that presents with deep vein thrombosis found to be due to compression by a large posterior tibial artery pseudoaneurysm which ultimately leads to the patient's diagnosis. This case highlights the need for a multidisciplinary approach involving vascular surgery, internal medicine, genetics, and other health care providers for patients with vascular type EDS.
Lipinski
Michael J
MJ
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia 22908-0386, USA. slipinski@virginia.edu
Lipinski
Shawn E
SE
Kripalani
Sanjay
S
Friesen
Lindsay D
LD
Uthlaut
Brian S
BS
Braddock
Stephen R
SR
D017541:Aneurysm, False / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D000792:Angiography; D024061:Collagen Type III / Q000235:genetics; D004535:Ehlers-Danlos Syndrome / Q000145:classification / Q000150:complications* / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D020125:Mutation, Missense; D016909:Tibial Arteries; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000209:etiology*; D055815:Young Adult
C439971:COL3A1 protein, human; D024061:Collagen Type III