title: Use of high-throughput crystallography and in silico methods for structure-based drug design.
authors.affiliation: ActiveSight, San Diego, California 92121, USA.
authors.forename: Leslie W
authors.initials: LW
authors.lastname: Tari
authors.forename: Duncan E
authors.initials: DE
authors.lastname: McRee
authors.forename: Andy J
authors.initials: AJ
authors.lastname: Jennings
mesh_terms: D002401:Cathepsin B / Q000037:antagonists & inhibitors; D003461:Crystallography / Q000379:methods*; D015195:Drug Design; D008024:Ligands; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D011480:Protease Inhibitors / Q000737:chemistry; D012371:Robotics; D014961:X-Ray Diffraction
chemical_list: D008024:Ligands; D004364:Pharmaceutical Preparations; D011480:Protease Inhibitors; D002401:Cathepsin B