Videonystagmography to assess eyelid dynamic disorders.
OBJECTIVE
Apply a videonystagmography (VNG) device to study indirectly blinking in patients with essential blepharospasm.


METHODS
A VNG device was used to study the pupillary occlusion. It was recorded and analyzed as indirect parameters of blinking in 23 essential blepharospasm on day 0, month 1, and month 3 following botulinum toxin injection using VNG.


RESULTS
Botulinum toxin significantly reduced pupillary occlusions (PO) frequency (9.6 PO/min on D0 and 4.7 PO/min on M1 (p = 0.004), and average PO time (0.95 sec on D0 and 0.58 sec on M1 (p = 0.03) for PO higher than 0.3 sec. On the other hand, it does not have any action on frequency (32.4 PO/min on D0 and 31.3 PO/min on M1 (p = 0.7) and average PO time (0.16 sec on D0 and 0.15 sec on M1 (p = 0.4) of PO lower than 0.3 sec.


CONCLUSIONS
Video acquisition computer-assisted makes it possible to measure blinking parameters indirectly in real time and to assess essential blepharospasm objectively. The protocol analysis of PO is attractive for indirect analysis of blinking.
Casse
Guillaume
G
Ophthalmology Department, CHU Dupuytren, Cedex, France. casse.guillaume@yahoo.fr
Adenis
Jean-Paul
JP
Sauvage
Jean-Pierre
JP
Robert
Pierre-Yves
PY
D000368:Aged; D000369:Aged, 80 and over; D001764:Blepharospasm / Q000188:drug therapy* / Q000503:physiopathology*; D001767:Blinking; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D011681:Pupil Disorders / Q000188:drug therapy / Q000503:physiopathology; D012044:Regression Analysis; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014741:Video Recording
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A