title: [Evaluation of peripherally inserted central catheters in high risk newborns].
abstract: OBJECTIVE
  To evaluate the feasibility and safety of the peripherally inserted central catheters (PICC) as a venous access for newborns who need a long-term venous transfusion.
  
  
  METHODS
  Sixty-five newborns receiving PICC and 80 newborns receiving peripheral intravenous catheters (PIV) from April 2006 to February 2008 were included in this study. A retrospective cohort study was used to compare the indwelling time of catheters, catheter-related mechanical complications, the incidence of sepsis, and the mortality between the two groups.
  
  
  RESULTS
  The indwelling time of catheters in the PICC and the PIV groups was 18.75+/-7.62 days (range:7-62 days) and 1.49+/-0.57 days (range: 30 minutes to 4 days) respectively. The indwelling time of catheters in the PICC group was significantly longer than that in the PIV group (<0.01). The incidence of catheter-related mechanical complications in the PICC group was significantly lower than that in the PIV group (27.7% vs 63.8%; <0.01). There were no significant differences in the incidence of sepsis and the mortality between the two groups.
  
  
  CONCLUSIONS
  The application of PICC can cause a decrease in the number of venous puncture. PICC is a safe and effective venous access in newborns.
authors.affiliation: Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Xia
authors.forename: Ying
authors.initials: Y
authors.lastname: Xiong
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Hu
authors.forename: De-Zhi
authors.initials: DZ
authors.lastname: Mu
mesh_terms: D002405:Catheterization, Central Venous / Q000009:adverse effects; D002406:Catheterization, Peripheral / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D018805:Sepsis / Q000209:etiology; D013997:Time Factors