title: Glossitis with linear lesions: an early sign of vitamin B12 deficiency.
abstract: The classic oral manifestations of vitamin B(12) deficiency are considered nonspecific. We describe 4 patients with oral linear lesions associated with vitamin B(12) deficiency. Patients were free of neurologic symptoms and anemia at diagnosis. We believe that glossitis with linear lesions is an early clinical sign of vitamin B(12) deficiency. We recommend the determination of vitamin B(12) in such patients, even in the absence of anemia.
authors.affiliation: Department of Dermatology, Hospital de Sant Joan de Déu de Sant Boi de Llobregat, Barcelona, Spain. 26449jge@comb.es
authors.forename: Jordi
authors.initials: J
authors.lastname: Graells
authors.forename: Rosa Maria
authors.initials: RM
authors.lastname: Ojeda
authors.forename: Cristina
authors.initials: C
authors.lastname: Muniesa
authors.forename: Jesus
authors.initials: J
authors.lastname: Gonzalez
authors.forename: Jose
authors.initials: J
authors.lastname: Saavedra
mesh_terms: D000328:Adult; D000368:Aged; D042241:Early Diagnosis; D005260:Female; D005928:Glossitis / Q000209:etiology* / Q000473:pathology*; D050031:Hashimoto Disease / Q000150:complications; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications; D013280:Stomatitis / Q000209:etiology / Q000473:pathology; D014059:Tongue / Q000473:pathology; D014806:Vitamin B 12 Deficiency / Q000150:complications*