title: Evaluation of diffuse liver steatosis by ultrasound, computed tomography, and magnetic resonance imaging: which modality is best?
abstract: OBJECTIVE
  To compare ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) determination of diffuse liver steatosis.
  
  
  METHODS
  Quantification of liver steatosis on ultrasound, CT, and MRI was correlated with histopathology in 67 patients.
  
  
  RESULTS
  Opposed-phase MRI demonstrated the highest correlation with steatosis (0.68 and 0.69, P<.01; intraclass correlation coefficient, 0.93). Spearman's correlation (and intraclass correlation) coefficients were lowest for ultrasound [0.54, 0.33 (0.40)] and enhanced CT [0.33, 0.39 (0.97)].
  
  
  CONCLUSIONS
  Opposed-phase MRI demonstrated best overall performance for determining steatosis.
authors.affiliation: Department of Radiology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA. aliya.qayyum@radiology.ucsf.edu
authors.forename: Aliya
authors.initials: A
authors.lastname: Qayyum
authors.forename: Daryl M
authors.initials: DM
authors.lastname: Chen
authors.forename: Richard S
authors.initials: RS
authors.lastname: Breiman
authors.forename: Antonio C
authors.initials: AC
authors.lastname: Westphalen
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Yeh
authors.forename: Kirk D
authors.initials: KD
authors.lastname: Jones
authors.forename: Ying
authors.initials: Y
authors.lastname: Lu
authors.forename: Fergus V
authors.initials: FV
authors.lastname: Coakley
authors.forename: Peter W
authors.initials: PW
authors.lastname: Callen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005234:Fatty Liver / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D055815:Young Adult