Occam's dull razor: MDM2 and P/CAF keep Chk2 in check the hard way.
Grossman
Steven R
SR
Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA. Steven.Grossman@umassmed.edu
D064447:Checkpoint Kinase 2; D004249:DNA Damage; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D051736:Proto-Oncogene Proteins c-mdm2 / Q000378:metabolism*; D025801:Ubiquitin / Q000378:metabolism; D050880:p300-CBP Transcription Factors / Q000378:metabolism*; D000099224:p300-CBP-Associated Factor
D064447:Checkpoint Kinase 2; D046988:Proteasome Endopeptidase Complex; D017346:Protein Serine-Threonine Kinases; D051736:Proto-Oncogene Proteins c-mdm2; D025801:Ubiquitin; D050880:p300-CBP Transcription Factors; D000099224:p300-CBP-Associated Factor