The state of cerebral hemodynamics in conditions of prolonged adaptation to hypercapnic hypoxia.
Intermittent hypercapnic hypoxia was accompanied by increases in cerebral vascular resistance, decreases in the reactivity of cerebral vessels to hypercapnia, and increases in the collateral reserve and rate of autoregulation of brain blood flow. These changes were an important component of the mechanism increasing the tolerance of the brain to ischemia in response to training with hypercapnic hypoxia.
Kulikov
V P
VP
Federal Agency for Health and Social Development, Altai State Medical University, 40 Lenin Prospekt, Barnaul, 656038, Altai Region, Russia. kulikov@agmu.ru
Bespalov
A G
AG
Yakushev
N N
NN
D000222:Adaptation, Physiological; D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D006935:Hypercapnia / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology*; D020768:Middle Cerebral Artery / Q000502:physiology; D013997:Time Factors