title: Intracranial facial nerve grafting after removal of vestibular schwannoma.
abstract: OBJECTIVE
  The objectives of this study were to evaluate outcomes from facial nerve (FN) cable grafting in patients who experienced FN transection during vestibular schwannoma removal and to compare the FN outcomes of patients who underwent FN grafting by using fibrin glue with those of patients who underwent FN grafting by using microsuture.
  
  
  METHODS
  We retrospectively evaluated a series of 33 patients in whom FN grafting was achieved either by using microsuture (8 cases) or fibrin glue (25 cases). Immediate repair of the FN was performed in all cases at the time of initial resection. The patients FN function was assessed preoperatively, in the immediate postoperative period, and at 3, 6, 9, and 12 months or more postoperatively using the House-Brackmann grading system. All patients had at least 1-year follow-up.
  
  
  RESULTS
  At 12 months, a House-Brackmann grade III was achieved in 75% of those who underwent cable nerve graft interposition by using microsuture and in 76% of those who underwent cable nerve graft interposition by using fibrin glue. Analysis of final FN function outcomes demonstrated no statistically significant difference in FN outcomes between the 2 groups (P = .891, Mann-Whitney U test; P = .1, Fisher exact test).
  
  
  CONCLUSIONS
  The functional results after FN cable grafting by using fibrin glue exclusively were equivalent to those obtained with microsuture. However, the technique of FN repair by means of fibrin glue is technically simple, less time-consuming, and imparts less trauma on the nerve than does the traditional suture method.
authors.affiliation: Department of Otolaryngology, University of Parma, Parma, Italy. andrea.bacciu@unipr.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Bacciu
authors.forename: Maurizio
authors.initials: M
authors.lastname: Falcioni
authors.forename: Enrico
authors.initials: E
authors.lastname: Pasanisi
authors.forename: Filippo
authors.initials: F
authors.lastname: Di Lella
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Lauda
authors.forename: Sean
authors.initials: S
authors.lastname: Flanagan
authors.forename: Mario
authors.initials: M
authors.lastname: Sanna
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D020220:Facial Nerve Injuries / Q000209:etiology / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013536:Suture Techniques; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives