One sensor fits all--a new approach in monitoring brain physiology.
Oxygen plays a pivotal role as a nutrient to the brain. Monitoring partial pressure of oxygen (ptO2) has been shown to correlate with outcome after brain injury if certain tissue-ptO2-goals can be achieved. Oxford Optronix has recently developed a new fiber-optic based sensor (MPBS) with a large tissue sampling volume and long-term stability up to 10 days. Direct comparison of the MPBS sensor with the Licox system was performed using an in-vitro and in-vivo model. No statistically significant differences between the MPBS and the Licox sensor in different settings were found. The response times to a sudden drop in ptO2 was faster for the MPBS than for the Licox probes (time of 80% signal change; 65 +/- 11 vs 110 +/- 14 s; p<0.05).
Doll
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Department of Pediatrics, HELIOS Klinikum Wuppertal, Witten/Herdecke University, Wuppertal, Germany, 42283.
Davies
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N
Douglas
S L E
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Kipfmueller
F
F
Maegele
M
M
Pauly
R
R
Woebker
G
G
Obeid
A N
AN
Truebel
H
H
D000818:Animals; D001921:Brain / Q000502:physiology*; D002245:Carbon Dioxide / Q000378:metabolism; D008991:Monitoring, Physiologic / Q000379:methods*; D013552:Swine
D002245:Carbon Dioxide