title: A case of bilateral presumed chikungunya neuroretinitis.
abstract: Chikungunya fever is a relatively rare from of vector-borne viral fever caused by chikungunya virus and spread by bites of the Aedes aegypti and Aedes albopictus mosquito. Epidemics of chikungunya fever have been reported in the past from different parts of the world. Although the virus had been passive for quite some time, recent reports of outbreaks of chikungunya fever in several parts of Southern India have confirmed the re-emergence of this virus. Symptoms of this infection include abrupt onset of fever, chills, and headache, rash, severe joint pain, conjunctival injection and photophobia. Ocular manifestations have been recently reported with this infection. We report a case of a 48-year-old female patient, who presented with defective vision two weeks after a serology proven chikungunya infection. There was bilateral neuroretinitis with peripapillary cotton wool spots. These findings should be kept in mind as an ocular manifestation of chikungunya virus infection.
authors.affiliation: Vitreoretinal Services, Giridhar Eye Institute, Cochin, India. girieye@vsnl.com
authors.forename: G
authors.initials: G
authors.lastname: Mahesh
authors.forename: A
authors.initials: A
authors.lastname: Giridhar
authors.forename: Archis
authors.initials: A
authors.lastname: Shedbele
authors.forename: Ram
authors.initials: R
authors.lastname: Kumar
authors.forename: S J
authors.initials: SJ
authors.lastname: Saikumar
mesh_terms: D018354:Alphavirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D000914:Antibodies, Viral / Q000097:blood; D002646:Chikungunya virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D005260:Female; D005451:Fluorescein Angiography; D007839:Functional Laterality; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008875:Middle Aged; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D016133:Polymerase Chain Reaction; D011239:Prednisolone / Q000627:therapeutic use; D012367:RNA, Viral / Q000032:analysis; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D014792:Visual Acuity
chemical_list: D000914:Antibodies, Viral; D005938:Glucocorticoids; D007075:Immunoglobulin M; D012367:RNA, Viral; D011239:Prednisolone