title: [Correlation analysis between plasma levels of 25-hydroxy vitamin D3 and osteocalcin in patients with aggressive periodontitis].
abstract: OBJECTIVE
  To explore the relationship between plasmatic 25-hydroxy vitamin D3 (25OHD3) level and plasmatic osteocalcin level in patients with aggressive periodontitis (AgP).
  
  
  METHODS
  Thirty four AgP patients and 29 healthy controls were included in this study. 25OHD3 and osteocalcin levels in plasma were measured using commercially available radioimmunoassay kits. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were measured using a standard hospital analytical technique.
  
  
  RESULTS
  Plasmatic 25OHD3 level was significantly higher in AgP patients than that in healthy controls (8.65 microg/L vs 3.10 microg/L; P<0.01). Osteocalcin level was also significantly higher in AgP patients than that in healthy subjects (1.0 microg/L vs 0.8 microg/L; P=0.028). AST level was significantly lower in AgP patients than that in healthy controls(20.0 U/L vs 23.0 U/L). No correlations between the plasmatic levels of 25OHD3 and osteocalcin were detected in AgP patients or in healthy controls (r=0.271, P=0.12; r=-0.356, P=0.58).
  
  
  CONCLUSIONS
  Plasmatic 25OHD3 and osteocalcin concentrations were not correlated but might be influenced by AgP.
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Kai-ning
authors.initials: KN
authors.lastname: Liu
authors.forename: Huan-xin
authors.initials: HX
authors.lastname: Meng
authors.forename: Xiao-lin
authors.initials: XL
authors.lastname: Tang
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhi-bin
authors.initials: ZB
authors.lastname: Chen
authors.forename: Dong
authors.initials: D
authors.lastname: Shi
authors.forename: Xiang-hui
authors.initials: XH
authors.lastname: Feng
authors.forename: Rui-fang
authors.initials: RF
authors.lastname: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D010520:Aggressive Periodontitis / Q000097:blood*; D002112:Calcifediol / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D015675:Osteocalcin / Q000097:blood*; D055815:Young Adult
chemical_list: D015675:Osteocalcin; D002112:Calcifediol