title: Chronic inflammatory demyelinating polyradiculoneuropathy, in an 8-year-old girl, complicated by deafness and kidney fibrosis.
abstract: Based on case history and clinical and electrophysiological examinations, the authors report on a case of an 8-year-old girl who was diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy. The disease was complicated by deafness and kidney fibrosis. During treatment with methylprednisolone and intravenous immunoglobulin, followed by mycophenolate mofetil, prompt improvement of neurological findings occurred. The improvement of hearing was poor. Because the pathogenesis of chronic inflammatory demyelinating polyradiculoneuropathy has still not been clear, and on the grounds of several cases of chronic inflammatory demyelinating polyradiculoneuropathy conjoined with the kidney disease described in literature (glomerulopathy, interstitial nephritis), every patient with chronic inflammatory demyelinating polyradiculoneuropathy needs to undergo the urinalyses.
authors.affiliation: Department of Nephrology, Institute for Child and Youth Health Care of Vojvodina, Novi Sad, Serbia. vesnasto@eunet.yu
authors.forename: Vesna D
authors.initials: VD
authors.lastname: Stojanovic
authors.forename: Aleksandra R
authors.initials: AR
authors.lastname: Doronjski
authors.forename: Slobodan D
authors.initials: SD
authors.lastname: Spasojevic
authors.forename: Vesna S
authors.initials: VS
authors.lastname: Pavlovic
authors.forename: Marko M
authors.initials: MM
authors.lastname: Nikolic
authors.forename: Branka B
authors.initials: BB
authors.lastname: Kovacevic
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D003638:Deafness / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D005355:Fibrosis / Q000150:complications / Q000188:drug therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007674:Kidney Diseases / Q000150:complications* / Q000188:drug therapy*; D008775:Methylprednisolone / Q000627:therapeutic use; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D009431:Neural Conduction; D018696:Neuroprotective Agents / Q000627:therapeutic use; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D018696:Neuroprotective Agents; D009173:Mycophenolic Acid; D008775:Methylprednisolone