title: Continuous glucose monitoring as a tool to identify hyperglycaemia in non-diabetic patients with acute coronary syndromes.
abstract: OBJECTIVE
  To explore the occurrence and the distribution of glucose excursions > 7.8 mmol/l by continuous glucose monitoring (CGM) in non-diabetic patients admitted with acute coronary syndrome (ACS).
  
  
  METHODS
  Twenty-one non-diabetic patients without baseline hyperglycaemia admitted for ACS wore a continuous glucose monitoring system (CGMS) for a median period of 45.6 h. Occurrence and 24-h distribution of time spent with blood glucose > 7.8 mmol/l (TS > 7.8) were retrospectively investigated.
  
  
  RESULTS
  CGMS data disclosed time spent > 7.8 in 17 patients, whereas only seven of them showed at least one capillary blood glucose test value above the threshold for the same time period. Glucose excursions were detectable earlier from CGMS data. Hyperglycaemia was detected most frequently in the morning, more than 2 h after breakfast.
  
  
  CONCLUSIONS
  CGM discloses early and frequent hyperglycaemia in non-diabetic patients with ACS. Intensive glucose monitoring during the morning time period is the most efficient in screening for hyperglycaemia and could be a valuable guide to initiating insulin therapy and to further investigate outcomes in ACS.
authors.affiliation: Endocrinology Department, CHU Montpellier, Université Montpellier, Montpellier, France. regis.radermecker@ulg.ac.be
authors.forename: R P
authors.initials: RP
authors.lastname: Radermecker
authors.forename: A
authors.initials: A
authors.lastname: Sultan
authors.forename: C
authors.initials: C
authors.lastname: Piot
authors.forename: A S
authors.initials: AS
authors.lastname: Remy
authors.forename: A
authors.initials: A
authors.lastname: Avignon
authors.forename: E
authors.initials: E
authors.lastname: Renard
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000379:methods; D010507:Periodicity; D019518:Postprandial Period
chemical_list: D001786:Blood Glucose