title: Influence of femoral stem geometry, material and extent of porous coating on bone ingrowth and atrophy in cementless total hip arthroplasty: an iterative finite element model.
abstract: This work presents a computational model for the concurrent study of bone remodelling and ingrowth around cementless femoral stems in total hip arthroplasty. It is assumed that biological fixation depends upon the magnitude of relative displacement at the bone-stem interface as well as an ongoing updating of interface conditions during the remodelling process. The remodelling model determines the distribution of bone density by producing the stiffest structure for a given set of biological conditions at the point of equilibrium in bone turnover. Changes in bone density and patterns of ingrowth are compared for different stem geometries, materials and lengths of surface coating. Patterns of bone ingrowth on the tapered stem were independent of extent of porous coating, while ingrowth varied with the length of coating on the cylindrical stem. This model integrates knowledge of under what mechanical conditions bone ingrowth occurs on prosthetic stem surfaces with remodelling behaviour over time.
authors.affiliation: Instituto Superior Tecnico, Technical University of Lisbon, Lisbon, Portugal. jfolgado@dem.ist.utl.pt
authors.forename: J
authors.initials: J
authors.lastname: Folgado
authors.forename: P R
authors.initials: PR
authors.lastname: Fernandes
authors.forename: C R
authors.initials: CR
authors.lastname: Jacobs
authors.forename: V D
authors.initials: VD
authors.lastname: Pellegrini
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000379:methods; D001284:Atrophy; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D015519:Bone Density; D016723:Bone Remodeling; D020099:Coated Materials, Biocompatible; D005269:Femur / Q000473:pathology / Q000503:physiopathology; D020342:Finite Element Analysis; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D008422:Materials Testing; D008954:Models, Biological; D016348:Osseointegration; D011474:Prosthesis Design
chemical_list: D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible