Palladium-catalyzed decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide.
A highly effective decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide catalyzed by the combination of palladium chloride and CyJohnPhos in the presence of Ag2CO3 as an additive is described. The desired carbon-carbon bond formation proceeds efficiently with good functional-group tolerance.
Wang
Zhiyong
Z
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Ding
Qiuping
Q
He
Xiaodan
X
Wu
Jie
J