Inhibition of acetylcholinesterase activity by dihydro-beta-agarofuran sesquiterpenes isolated from Chilean Celastraceae.
A series of agarofuran compounds isolated from Chilean Celastraceae were evaluated in vitro for their cholinesterase inhibitory activities by UV spectroscopy.
Alarcón
Julio
J
Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile. jualarcon@ubiobio.cl
Astudillo
Luís
L
Gutierrez
Margarita
M
D000110:Acetylcholinesterase / Q000378:metabolism*; D029753:Celastraceae / Q000737:chemistry*; D002677:Chile; D002800:Cholinesterase Inhibitors / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D007700:Kinetics; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D012639:Seeds / Q000737:chemistry; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D002800:Cholinesterase Inhibitors; D010936:Plant Extracts; D012717:Sesquiterpenes; D000110:Acetylcholinesterase