Chronic kidney disease-mineral and bone disorder (CKD-MBD): a new term for a complex approach.
The global widespread of the chronic kidney disease (CKD) is a worldwide health problem. Its increasing incidence and prevalence and adverse outcomes (including decreased quality of life, increased morbidity and mortality) represents a huge challenge for all recent health are systems. Reflecting this situation, the new, global initiative (KDIGO) was established to enhance communication and clinical decision-making, promote the use of evidence based medicine and facilitate clinical research. The new definition, evaluation and classification of "renal osteodystrophy"; has been one of the first outcome of this initiative, suggesting the topic of chronic kidney disease--mineral and bone disorder (CKD-MBD) to be a hot problem of recent nephrology. The new terminology is consistent with a recent view on this topic and describes CKD-MBD as a complex syndrome, including abnormal mineral and PTH metabolism, altered bone structure as far as extra-skeletal calcifications.
Svára
Frantisek
F
Department of Medicine Strahov, General University Hospital, Prague, Czech Republic. fsvara@atlas.cz
D000047:Academies and Institutes / Q000458:organization & administration; D002114:Calcinosis / Q000209:etiology / Q000628:therapy; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D017281:Cost of Illness; D019317:Evidence-Based Medicine; D014943:Global Health; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000453:epidemiology; D009398:Nephrology / Q000379:methods* / Q000592:standards / Q000639:trends; D009937:Organizational Objectives; D017063:Outcome Assessment, Health Care; D017410:Practice Guidelines as Topic; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D009626:Terminology as Topic; D017749:Total Quality Management / Q000458:organization & administration