title: Cocaine-associated lower limb ischemia.
abstract: Cocaine-associated thrombosis has been reported in the literature with reports of vascular injuries to cardiac, pulmonary, intestinal, placental, and musculoskeletal vessels; however, injury of the pedal vessels is rare. We report on a 31-year-old man who presented 2 months following a cocaine binge with limb-threatening ischemia without an otherwise identifiable embolic source. Angiography confirmed extensive occlusive disease of the tibioperoneal vessels. The patient improved following therapy with heparin and a prostacyclin analogue. Cocaine-induced thrombosis should be considered in patients presenting with acute arterial insufficiency in the lower limb without any other identifiable cause.
authors.affiliation: Department of Vascular Surgery, Beaumont Hospital, Dublin, Ireland.
authors.forename: Chris G
authors.initials: CG
authors.lastname: Collins
authors.forename: Deirdre
authors.initials: D
authors.lastname: Seoighe
authors.forename: Adrian
authors.initials: A
authors.lastname: Ireland
authors.forename: David
authors.initials: D
authors.lastname: Bouchier-Hayes
authors.forename: Frank
authors.initials: F
authors.lastname: McGrath
mesh_terms: D000328:Adult; D019970:Cocaine-Related Disorders / Q000150:complications*; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use; D007383:Intermittent Claudication / Q000000981:diagnostic imaging / Q000209:etiology; D007511:Ischemia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D011859:Radiography; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents; D016285:Iloprost