title: [Site of local surgery in adenocarcinoma of the rectum T2N0M0].
abstract: BACKGROUND
  The local exeresis adenocarcinoma of the rectum T(2)N(0)M(0) (ADC-T2), using transanal endoscopic microsurgery (TEM), has the benefit of achieving lower morbidity with a better quality of life. However, local occurrence of the local exeresis is greater than 20%, which is unacceptable these days.
  
  
  METHODS
  Prospective, observational follow up study. The tumours committee agreed that those ADC-T2 patients could have the following treatments: total mesorectal excision (TME), simple TEM, TEM with postoperative chemo- and radiotherapy (Ct-Rt), preoperative Ct-Rt with subsequent TEM and radical surgical rescue (TME) within at least 4 weeks.
  
  
  RESULTS
  Of the 146 patients operated on using TEM, 75 had adenocarcinomas, 59 adenomas, 6 scarring wounds, 5 carcinoids and 1 GIST. Of the adenocarcinomas 22 were ADC-T2. Follow up: median of 16 months (range, 3-32 months). The overall local recurrence was 18% (4/22). According to the treatment strategy the local occurrence was: TEM as the only procedure, 20% (2/10). Radical surgical rescue was performed on 3 patients after TEM, with no local or systemic recurrences. TEM with Qt-Rt after surgery was performed on 6 patients, with a local recurrence of 33% (2/6). Ct-Rt and subsequent TEM in 3 patients, with no local or systemic recurrences.
  
  
  CONCLUSIONS
  Treatment of ADC-T2 using simple TEM is not effective. The combination of Ct-Rt after TEM, does not improve the results of TME. It is possible to rescue those patients without changing the overall survival. Preoperative Ct-Rt and TEM appears to be the approach that obtains a clinical and histological response, although a response is needed by clinical trials.
authors.affiliation: Servicio de Cirugía General y del Aparato Digestivo, Corporación Sanitaria Parc Taulí, Sabadell, Barcelona, España. jserraa@tauli.cat
authors.forename: Xavier
authors.initials: X
authors.lastname: Serra Aracil
authors.forename: Jordi
authors.initials: J
authors.lastname: Bombardó Juncá
authors.forename: Laura
authors.initials: L
authors.lastname: Mora López
authors.forename: Manuel
authors.initials: M
authors.lastname: Alcantara Moral
authors.forename: Isidro
authors.initials: I
authors.lastname: Ayguavives Garnica
authors.forename: Ana
authors.initials: A
authors.lastname: Darnell Marti
authors.forename: Alex
authors.initials: A
authors.lastname: Casalots Casado
authors.forename: Carles
authors.initials: C
authors.lastname: Pericay Pijaume
authors.forename: Rafael
authors.initials: R
authors.lastname: Campo Fernández de Los Ríos
authors.forename: Salvador
authors.initials: S
authors.lastname: Navarro Soto
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D013505:Digestive System Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000601:surgery*