title: Polyvalent type IV sensitizations to multiple fragrances and a skin protection cream in a metal worker.
abstract: Fragrances are very common in everyday products. A metalworker with chronic hand eczema and previously diagnosed type IV sensitizations to epoxy resin, balsam of Peru, fragrance mix and fragrance mix II was diagnosed with additional type IV sensitizations to geraniol, hydroxycitronellal, lilial, tree moss, oak moss absolute, citral, citronellol, farnesol, Lyral, fragrance mix II and fragrance mix (with sorbitan sesquioleate). In addition, a type IV sensitization to the skin protection cream containing geraniol and citronellol used at the workplace was detected, and deemed occupationally relevant in this case. The patient could have had contact to fragrances through private use of cosmetics and detergents. On the other hand, the fragrance-containing skin protection cream supports occupational exposure. This case report demonstrates that fragrance contact allergy has to be searched for and clarified individually, which requires a thorough history and a detailed analysis of the work place.
authors.affiliation: Department of Clinical Social Medicine, Occupational and Environmental Dermatology, University Hospital Heidelberg, Germany.
authors.forename: Zita
authors.initials: Z
authors.lastname: Tanko
authors.forename: Arna
authors.initials: A
authors.lastname: Shab
authors.forename: Thomas Ludwig
authors.initials: TL
authors.lastname: Diepgen
authors.forename: Elke
authors.initials: E
authors.lastname: Weisshaar
mesh_terms: D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology*; D004643:Emollients / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D010476:Perfume / Q000009:adverse effects*
chemical_list: D004643:Emollients; D010476:Perfume