title: Transition-metal-free intermolecular amination of sp3 C-H bonds with sulfonamides.
abstract: An efficient transition-metal-free intermolecular benzylic amidation with sulfonamides is described. Various valuable nitrogen-containing compounds, including amines, beta-chloro amine, amino alcohol, alpha-, beta-amino ester, and N-sulfonyl imine, are generated from the preferential N-functionalization of saturated benzylic C-H bonds. The potential of this reaction system also lies in the fact it can be developed into an environmentally friendly intermolecular amidation process.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China. rhfan@fudan.edu.cn
authors.forename: Renhua
authors.initials: R
authors.lastname: Fan
authors.forename: Weixun
authors.initials: W
authors.lastname: Li
authors.forename: Dongming
authors.initials: D
authors.lastname: Pu
authors.forename: Li
authors.initials: L
authors.lastname: Zhang