Merkel cell polyomavirus DNA in respiratory specimens from children and adults.
Merkel cell polyomavirus (MCPyV) DNA was detected in 7 (1.3%) of 526 respiratory tract samples from patients in Australia with upper or lower respiratory tract symptoms. Partial T antigen and major capsid protein sequences of MCPyV identified in respiratory secretions showed high homology (99%-100%) to those found in Merkel cell carcinoma.
Bialasiewicz
Seweryn
S
Research Section, Queensland Paediatric Infectious Diseases Laboratory, Sir Albert Sakzewski Virus Research Centre, Brisbane, Queensland, Australia. seweryn@uq.edu.au
Lambert
Stephen B
SB
Whiley
David M
DM
Nissen
Michael D
MD
Sloots
Theo P
TP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000957:Antigens, Viral, Tumor / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D015266:Carcinoma, Merkel Cell / Q000821:virology; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000032:analysis / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011120:Polyomavirus / Q000235:genetics / Q000302:isolation & purification*; D027601:Polyomavirus Infections / Q000453:epidemiology / Q000821:virology; D011793:Queensland / Q000453:epidemiology; D012137:Respiratory System / Q000821:virology*; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology; D017422:Sequence Analysis, DNA; D055815:Young Adult
D000957:Antigens, Viral, Tumor; D036022:Capsid Proteins; D004279:DNA, Viral