title: Ketamine/xylazine anesthesia alters [11C]MNPA binding to dopamine D2 receptors and response to methamphetamine challenge in monkey brain.
authors.affiliation: Central Research Laboratory, Hamamatsu Photonics K. K., 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ohba
authors.forename: Norihiro
authors.initials: N
authors.lastname: Harada
authors.forename: Shingo
authors.initials: S
authors.lastname: Nishiyama
authors.forename: Takeharu
authors.initials: T
authors.lastname: Kakiuchi
authors.forename: Hideo
authors.initials: H
authors.lastname: Tsukada
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000778:Anesthetics, Dissociative / Q000494:pharmacology; D000818:Animals; D001058:Apomorphine / Q000031:analogs & derivatives* / Q000378:metabolism; D001667:Binding, Competitive / Q000187:drug effects* / Q000502:physiology; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D001923:Brain Chemistry / Q000187:drug effects / Q000502:physiology; D002250:Carbon Radioisotopes; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism; D018765:Dopamine Uptake Inhibitors / Q000494:pharmacology; D004347:Drug Interactions / Q000502:physiology; D007649:Ketamine / Q000494:pharmacology*; D008253:Macaca mulatta; D008297:Male; D008694:Methamphetamine / Q000494:pharmacology*; D017448:Receptors, Dopamine D2 / Q000187:drug effects* / Q000378:metabolism; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology; D014991:Xylazine / Q000494:pharmacology*
chemical_list: D000316:Adrenergic alpha-Agonists; D000778:Anesthetics, Dissociative; D002250:Carbon Radioisotopes; D018765:Dopamine Uptake Inhibitors; D017448:Receptors, Dopamine D2; C064292:2-methoxy-N-n-propylnorapomorphine; D014991:Xylazine; D008694:Methamphetamine; D007649:Ketamine; D001058:Apomorphine