title: A nosocomial outbreak of norovirus infection masquerading as clostridium difficile infection.
abstract: Noroviruses (NoVs) are increasingly being recognized as important enteric pathogens. At a university-based hospital, we investigated a nosocomial outbreak of NoV infection that was originally attributed to Clostridium difficile. We describe here the unique challenges of the identification of NoVs as the true etiologic pathogen in an outbreak occurring in a health care setting, where C. difficile infection is endemic, as well as the important lessons learned.
authors.affiliation: Baylor College of Medicine, University of Texas-Houston School of Public Health, Houston, Texas, USA.
authors.forename: Hoonmo L
authors.initials: HL
authors.lastname: Koo
authors.forename: Nadim J
authors.initials: NJ
authors.lastname: Ajami
authors.forename: Zhi-Dong
authors.initials: ZD
authors.lastname: Jiang
authors.forename: Herbert L
authors.initials: HL
authors.lastname: Dupont
authors.forename: Robert L
authors.initials: RL
authors.lastname: Atmar
authors.forename: Debra
authors.initials: D
authors.lastname: Lewis
authors.forename: Patricia
authors.initials: P
authors.lastname: Byers
authors.forename: Paula
authors.initials: P
authors.lastname: Abraham
authors.forename: Ricardo A
authors.initials: RA
authors.lastname: Quijano
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Musher
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Young
mesh_terms: D017250:Caliciviridae Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000821:virology; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003428:Cross Infection / Q000453:epidemiology / Q000821:virology; D003937:Diagnosis, Differential; D004196:Disease Outbreaks; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology*; D006785:Hospitals, University; D006801:Humans; D029322:Norovirus / Q000302:isolation & purification*