title: Management of red cell alloimmunized pregnancies using conventional methods compared with that of middle cerebral artery peak systolic velocity.
abstract: The aim of this retrospective study was to find out the effect of change in the management of red cell alloimmunized pregnancies from conventional method of amniocentesis to the Doppler assessment of middle cerebral artery peak systolic velocity (MCA-PSV). There were 29 alloimmunized pregnancies affected by red cell antibodies. Ten cases were managed by amniocentesis and another 19 were managed by MCA-PSV measurements. The antenatal management and perinatal outcome of both groups are presented. This study suggests that the non-invasive monitoring should be the method of choice to monitor alloimmunized pregnancies.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital Lewisham, London, UK. ashis@sau3.freeserve.co.uk
authors.forename: Ashis
authors.initials: A
authors.lastname: Sau
authors.forename: Atef
authors.initials: A
authors.lastname: El-Matary
authors.forename: Lyn
authors.initials: L
authors.lastname: Newton
authors.forename: D C Jagat
authors.initials: DC
authors.lastname: Wickramarachchi
mesh_terms: D000649:Amniocentesis; D001663:Bilirubin / Q000097:blood; D001783:Blood Flow Velocity; D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology; D005865:Gestational Age; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D020768:Middle Cerebral Artery / Q000503:physiopathology*; D010789:Phototherapy; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012203:Rh Isoimmunization / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D016216:Ultrasonography, Prenatal / Q000379:methods*
chemical_list: D006454:Hemoglobins; D001663:Bilirubin