title: Pharmacological interactions of anti-microbial agents in odontology.
abstract: In this third article we describe the pharmacological interactions resulting from the use of anti-microbial agents. Although the antimicrobials prescribed in odontology are generally safe they can produce interactions with other medicaments which can give rise to serious adverse reactions which are well documented in clinical studies. Antibiotics with grave and dangerous life threatening consequences are erythromycin, clarithromycin and metronidazol and the anti-fungal agents are ketoconazol and itraconazol. Regarding the capacity of the anti-microbials to reduce the efficacy of oral anti-contraceptives the clinical studies to date are inconclusive, however, it would be prudent for the oral cavity specialist to point out the risk of a possible interaction. Therefore the specialist should be aware of possible interactions as a consequence of administering an antibiotic together with other medicaments the patient may be taking.
authors.affiliation: Department of Odontology, University of Granada, Campus de Cartuja, Granada, Spain. ggomez@ugr.es
authors.forename: Gerardo
authors.initials: G
authors.lastname: Gómez-Moreno
authors.forename: Javier
authors.initials: J
authors.lastname: Guardia
authors.forename: Antonio
authors.initials: A
authors.lastname: Cutando
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Calvo-Guirado
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D003813:Dentistry; D004347:Drug Interactions; D006801:Humans
chemical_list: D000890:Anti-Infective Agents