Lack of effect of subject posture on intravenous midazolam clearance: implications for hepatic cytochrome P450 3A phenotyping.
Ma
Joseph D
JD
Nafziger
Anne N
AN
Mylott
William
W
Haughey
David B
DB
Rocci
Mario L
ML
Bertino
Joseph S
JS
D051544:Cytochrome P-450 CYP3A / Q000187:drug effects*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008099:Liver / Q000098:blood supply* / Q000187:drug effects; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008874:Midazolam / Q000097:blood / Q000493:pharmacokinetics*; D011187:Posture / Q000502:physiology; D012039:Regional Blood Flow / Q000187:drug effects*
D051544:Cytochrome P-450 CYP3A; D008874:Midazolam