[Treatment of pain in chronic pancreatitis].
Abdominal pain is the most frequent symptom in patients with chronic pancreatitis. Between 70 and 90% of patients experience pain at some point in the course of their disease. In patients with alcoholic pancreatitis, pain is usually experienced at disease onset. Two distinct forms of idiopathic chronic pancreatitis can be distinguished: in early-onset (juvenile) idiopathic chronic pancreatitis, pain occurs initially, while in late-onset (senile) idiopathic chronic pancreatitis, pain is delayed or may even be absent. According to several authors, between 27 and 67% of patients require surgery due to lack of response to medical treatment. Pain may reoccur in more than 30% of patients who have undergone surgery and consequently, reintervention is not uncommon. Several treatment options are currently available: medical, endoscopic and surgical. The most appropriate treatment for each patient should be chosen on an individualized basis.
Guarner
Luisa
L
Servicio de Aparato Digestivo, Hospital Universitario Vall d'Hebron, Barcelona, España. lguarner@vhebron.net
Abu-Suboh
Monder
M
Dot
Joan
J
Olsina
Jorge
J
D017668:Age of Onset; D000700:Analgesics / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use; D017763:Autonomic Denervation; D002447:Celiac Plexus / Q000000981:diagnostic imaging / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002908:Chronic Disease; D003131:Combined Modality Therapy; D006801:Humans; D015282:Octreotide / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D010195:Pancreatitis / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology* / Q000532:radiotherapy / Q000601:surgery; D019512:Pancreatitis, Alcoholic / Q000503:physiopathology; D016032:Randomized Controlled Trials as Topic; D018084:Ultrasonography, Interventional
D000700:Analgesics; D000975:Antioxidants; D015282:Octreotide