Evaluation of rapid urine test for the detection of Helicobacter pylori infection in the Vietnamese population.
OBJECTIVE
This study attempted to assess the value of the RAPIRUN test for the diagnosis of Helicobacter pylori infection in the Vietnamese population.


METHODS
We recruited 148 Vietnamese patients undergoing upper gastrointestinal endoscopy during which five gastric biopsies were taken; blood and urine samples were collected from each patient. Helicobacter pylori infection status was determined by a combination of three different methods, including culture, immunohistochemistry, and serum ELISA. RAPIRUN tests were performed using urine samples.


RESULTS
The sensitivity, specificity, and accuracy of the RAPIRUN test in these Vietnamese patients were 79.5, 90.7, and 84.5%, respectively.


CONCLUSIONS
The RAPIRUN test is useful for the diagnosis of H. pylori infection in the Vietnamese population, showing high specificity, acceptable sensitivity, non-invasiveness, convenience, and rapidity.
Nguyen
Lam Tung
LT
Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu-city, Oita 879-5593, Japan. ngltung@med.oita-u.ac.jp
Uchida
Tomohisa
T
Tsukamoto
Yoshiyuki
Y
Trinh
Tuan Dung
TD
Ta
Long
L
Ho
Dang Quy Dung
DQ
Matsuhisa
Takeshi
T
Uchida
Masahiro
M
Takayama
Akiko
A
Hijiya
Naoki
N
Okimoto
Tadayoshi
T
Kodama
Masaaki
M
Murakami
Kazunari
K
Fujioka
Toshio
T
Moriyama
Masatsugu
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000652:urine*; D015169:Colony Count, Microbial; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000652:urine; D016480:Helicobacter pylori / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D014744:Vietnam; D055815:Young Adult
D000907:Antibodies, Bacterial; D011933:Reagent Kits, Diagnostic