title: Dexamethasone inner ear perfusion for subclinical endolymphatic hydrops.
abstract: We suggest that the term subclinical cochlear hydrops be used to describe patients presenting with aural fullness, stuffiness, or ear pressure when all other diagnoses have been excluded. We reviewed the charts of 20 patients who had presented with a chief complaint of aural fullness, stuffiness, or pressure and who underwent perfusion of the inner ear for 1 month with dexamethasone 4 or 10 mg/ml. The symptoms improved in 13 (68.4%) of 19 patients after treatment. None of these patients reported a worsening of symptoms, and no patient had worse hearing after perfusion. Complications were infrequent, and patients tolerated the treatment well. Perfusion of the inner ear appears to be a safe procedure with little risk.
authors.affiliation: Silverstein Institute, 1901 Floyd Street, Sarasota, FL 34239, USA. hsilverste@aol.com
authors.forename: Herbert
authors.initials: H
authors.lastname: Silverstein
authors.forename: Mathew
authors.initials: M
authors.lastname: Farrugia
authors.forename: Mark
authors.initials: M
authors.lastname: Van Ess
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D003907:Dexamethasone / Q000627:therapeutic use*; D007758:Ear, Inner / Q000187:drug effects; D018159:Endolymphatic Hydrops / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D012189:Retrospective Studies; D013063:Speech Discrimination Tests; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D003907:Dexamethasone