Characteristic profiles of instrumental activities of daily living in different subtypes of mild cognitive impairment.
OBJECTIVE
The purposes of this study were to describe restrictions in instrumental activities of daily living (IADL) in mild cognitive impairment (MCI) and to assess different patterns of IADL in each MCI subtype.


METHODS
A total of 566 participants, those not cognitively impaired (NCI; n = 311) and MCI patients (n = 255), 60-94 years old (71.25 +/- 6.00), were examined. Neuropsychological tests were administered to participants, and each MCI patient was classified into one of four subtypes. They completed the Barthel ADL and Seoul-IADL (S-IADL) for ADL measures.


RESULTS
There was a significant difference between NCI and MCI in terms of total S-IADL scores. ANOVA and a post hoc Dunnett analysis revealed that MCI patients performed significantly worse on four out of a total 15 items (i.e. telephone, transportation, finances and household appliances). ANCOVA showed a significant difference in S-IADL-MCI (4 of 15 items) between NCI and amnestic MCI-multiple domains after adjusting for age, gender, education and Geriatric Depression Scale (F = 4.257, d.f. = 1,556, p = 0.002).


CONCLUSIONS
These findings suggest that scorings of specific IADL items are different in MCI subjects, and these items can possibly help in the identification of MCI subtypes, especially amnestic MCI-multiple domains.
Kim
Kyung Ran
KR
Department of Psychiatry, Yonsei University College of Medicine, Seoul, South Korea.
Lee
Kang Soo
KS
Cheong
Hae-Kwan
HK
Eom
Jin-Sup
JS
Oh
Byoung Hoon
BH
Hong
Chang Hyung
CH
D000203:Activities of Daily Living / Q000523:psychology*; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D009483:Neuropsychological Tests; D012044:Regression Analysis; D012307:Risk Factors; D012959:Socioeconomic Factors