title: Unrelated stem cell transplant for infantile idiopathic myelofibrosis.
abstract: Idiopathic myelofibrosis (IMF) is a rare disease in children that can present during infancy and have a protracted course. The only known curative approach for this disease in adult patients is allogeneic stem cell transplant. We present two cases of IMF during infancy that did not resolve with supportive care measures. Both patients underwent unrelated stem cell transplant with complete resolution of their hematologic manifestations and resolution of the bone marrow fibrosis.
authors.affiliation: Pediatric Hematology/Oncology, Vanderbilt University, Nashville, Tennessee 37232-6310, USA. jennifer.domm@vanderbilt.edu
authors.forename: Jennifer
authors.initials: J
authors.lastname: Domm
authors.forename: Cassie
authors.initials: C
authors.lastname: Calder
authors.forename: Becky
authors.initials: B
authors.lastname: Manes
authors.forename: Christine
authors.initials: C
authors.lastname: Crossno
authors.forename: Hernan
authors.initials: H
authors.lastname: Correa
authors.forename: Haydar
authors.initials: H
authors.lastname: Frangoul
mesh_terms: D006801:Humans; D007223:Infant; D008297:Male; D055728:Primary Myelofibrosis / Q000473:pathology / Q000628:therapy*; D033581:Stem Cell Transplantation