[Fucoidan: advances in the study of its anti-inflammatory and anti-oxidative effects].
Fucoidan is a natural polysaccharide extracted from brown seaweeds, with a wide variety of biological features, especially the anti-inflammatory and anti-oxidative effects. Studies indicated that the anti-inflammatory effect of fucoidan related to its capacity to interact with the selectin or scavenger receptor on the cell membrane. Fucoidan can also inhibit the synthesis and release of reactive oxygen species (ROS), as well as promote its clearance, showing the anti-oxidative activity.
Cui
Yan-qiu
YQ
Key Laboratory of Neurodegenerative Disorders of the Ministry of Education, Department of Physiology, Capital Medical University, Beijing 100069, China.
Luo
Ding-zhen
DZ
Wang
Xiao-min
XM
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D011134:Polysaccharides / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D051116:Receptors, Scavenger / Q000378:metabolism; D012624:Seaweed / Q000737:chemistry*; D019087:Selectins / Q000378:metabolism
D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D011134:Polysaccharides; D017382:Reactive Oxygen Species; D051116:Receptors, Scavenger; D019087:Selectins; C007789:fucoidan