title: Doppler analysis of uterine perfusion and ovarian stromal blood flow in polycystic ovary syndrome.
abstract: OBJECTIVE
  To investigate blood flow velocity in the ovarian stromal artery and uterine artery in women with polycystic ovary syndrome (PCOS) and to correlate these velocities with clinical and biochemical parameters.
  
  
  METHODS
  A prospective study was carried out in 55 patients with PCOS and 42 age-matched women who did not have PCOS. Clinical, biochemical, and hormonal characteristics, and utero-ovarian Doppler ultrasound blood flow parameters were determined, and correlations between the parameters were evaluated.
  
  
  RESULTS
  Ovarian stromal blood flow was higher (P<0.01) and uterine perfusion was lower (P<0.01) in women with PCOS compared with women who did not have PCOS. Ovarian stromal artery pulsatility index (PI) was inversely correlated with levels of dehydroepiandrosterone sulfate (DHEAS) and insulin-like growth factor-1, and with the luteinizing hormone/follicle-stimulating hormone ratio. There was a positive correlation between uterine artery PI and DHEAS level.
  
  
  CONCLUSIONS
  Doppler analysis of the uterine and intraovarian arteries may provide additional information about the etiopathogenesis of PCOS and partly explain the clinical implications of the condition.
authors.affiliation: Department of Obstetrics and Gynecology, Yuzuncu Yil University, Van, Turkey. ertanadali@yahoo.com
authors.forename: Ertan
authors.initials: E
authors.lastname: Adali
authors.forename: Ali
authors.initials: A
authors.lastname: Kolusari
authors.forename: Fulya
authors.initials: F
authors.lastname: Adali
authors.forename: Recep
authors.initials: R
authors.lastname: Yildizhan
authors.forename: Mertihan
authors.initials: M
authors.lastname: Kurdoglu
authors.forename: Hanim Guler
authors.initials: HG
authors.lastname: Sahin
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011446:Prospective Studies; D012039:Regional Blood Flow; D013002:Somatomedins / Q000378:metabolism; D018615:Ultrasonography, Doppler, Color; D018617:Ultrasonography, Doppler, Pulsed; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging; D055815:Young Adult
chemical_list: D013002:Somatomedins; D019314:Dehydroepiandrosterone Sulfate; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone