A kinase-START gene confers temperature-dependent resistance to wheat stripe rust.
Stripe rust is a devastating fungal disease that afflicts wheat in many regions of the world. New races of Puccinia striiformis, the pathogen responsible for this disease, have overcome most of the known race-specific resistance genes. We report the map-based cloning of the gene Yr36 (WKS1), which confers resistance to a broad spectrum of stripe rust races at relatively high temperatures (25 degrees to 35 degrees C). This gene includes a kinase and a putative START lipid-binding domain. Five independent mutations and transgenic complementation confirmed that both domains are necessary to confer resistance. Yr36 is present in wild wheat but is absent in modern pasta and bread wheat varieties, and therefore it can now be used to improve resistance to stripe rust in a broad set of varieties.
Fu
Daolin
D
Department of Plant Sciences, University of California, Davis, CA 95616, USA.
Uauy
Cristobal
C
Distelfeld
Assaf
A
Blechl
Ann
A
Epstein
Lynn
L
Chen
Xianming
X
Sela
Hanan
H
Fahima
Tzion
T
Dubcovsky
Jorge
J
D000595:Amino Acid Sequence; D001487:Basidiomycota / Q000472:pathogenicity*; D003001:Cloning, Molecular; D003433:Crosses, Genetic; D015536:Down-Regulation; D017343:Genes, Plant; D006358:Hot Temperature; D007113:Immunity, Innate; D008969:Molecular Sequence Data; D010770:Phosphotransferases / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D020161:Physical Chromosome Mapping; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D030821:Plants, Genetically Modified; D014908:Triticum / Q000235:genetics* / Q000382:microbiology*
D010940:Plant Proteins; D010770:Phosphotransferases