Effects of plane of nutrition on oxidative stress in goats during the peripartum period.
This study aimed to monitor the effect of a high (HD; 140% of energy requirements) versus a low diet (LD; 80% energy requirements) on oxidative status in goats during the peripartum period. Blood samples were taken from all goats at -2, -1, 0 (partum), +2 and +4 weeks from delivery. Blood samples were assayed for their content of reactive oxygen metabolites (ROMs), thiol (SH) groups, total antioxidant capacity (OXY) and for glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities. The observation that ROMs levels significantly increased during the peripartum period was accompanied by a decrease of GSH-Px activity at weeks 2 and 4 postpartum, which suggested that the goats might have experienced some degree of oxidative stress and lipid peroxidation. Overall, changes to the nutritional level of the diet had very little or no effect on redox homeostasis. The lack of any correlation between the biomarkers measured indicated that each oxidative stress marker responded differently, indicating that redox homeostasis was impaired in these dairy goats during the peripartum period.
Celi
Pietro
P
Faculty of Veterinary Science, University of Sydney, PMB 3, 425 Werombi Rd., Camden, NSW 2570, Australia. pietroc@camden.usyd.edu.au
Di Trana
Adriana
A
Claps
Salvatore
S
D000824:Animal Nutritional Physiological Phenomena / Q000502:physiology*; D000818:Animals; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D006041:Goats / Q000097:blood / Q000502:physiology*; D015227:Lipid Peroxidation; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology; D036801:Parturition; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase