Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers.
Enhanced brain reward function could contribute to resilience to trauma. Reward circuitry in active duty, resilient special forces (SF) soldiers was evaluated using functional magnetic resonance imaging during a monetary incentive delay task. Findings in this group of resilient individuals revealed unique patterns of activation during expectation of reward in the subgenual prefrontal cortex and nucleus accumbens area, regions pivotal to reward processes.
Vythilingam
Meena
M
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD, 20892, USA. meena.vythi@nih.gov
Nelson
Eric E
EE
Scaramozza
Matthew
M
Waldeck
Tracy
T
Hazlett
Gary
G
Southwick
Steven M
SM
Pine
Daniel S
DS
Drevets
Wayne
W
Charney
Dennis S
DS
Ernst
Monique
M
D000328:Adult; D001479:Basal Ganglia / Q000502:physiology / Q000503:physiopathology; D015415:Biomarkers; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000706:statistics & numerical data; D008297:Male; D008889:Military Personnel / Q000523:psychology / Q000706:statistics & numerical data*; D009042:Motivation; D009714:Nucleus Accumbens / Q000502:physiology; D010100:Oxygen / Q000097:blood; D017397:Prefrontal Cortex / Q000502:physiology; D055500:Resilience, Psychological; D012201:Reward; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology
D015415:Biomarkers; D010100:Oxygen