title: [Gonadotoxic effects of polychlorinated biphenyls in experiments on male rats].
abstract: The influence of Sovol, a commercial mixture of polychlorinated biphenyls (PCBs) on the reproductive system was studied on male rats. The results of the experiments showed that PCBs significantly decreased the body and testis weight, the number of the sperm cells in ejaculate and testicular tissue, blood levels of testosterone and estradiole. Increasing of peroxidation was also observed. The results suggested that the revealed disorders may play an important role in pathogenesis of male infertility caused by persistent organic pollutants.
authors.forename: E F
authors.initials: EF
authors.lastname: Agletdinov
authors.forename: F Kh
authors.initials: FKh
authors.lastname: Kamilov
authors.forename: E K
authors.initials: EK
authors.lastname: Alekhin
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
authors.forename: K V
authors.initials: KV
authors.lastname: Bulygin
authors.forename: L O
authors.initials: LO
authors.lastname: Makasheva
mesh_terms: D000818:Animals; D004785:Environmental Pollutants / Q000633:toxicity*; D004958:Estradiol / Q000097:blood; D007248:Infertility, Male / Q000139:chemically induced*; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D011078:Polychlorinated Biphenyls / Q000633:toxicity*; D051381:Rats; D013094:Spermatozoa / Q000187:drug effects*; D013737:Testis / Q000187:drug effects*; D013739:Testosterone / Q000097:blood
chemical_list: D004785:Environmental Pollutants; C053040:Sovol; D013739:Testosterone; D004958:Estradiol; D011078:Polychlorinated Biphenyls