title: What have we learnt from early rheumatoid arthritis cohorts?
abstract: Longitudinal and observational studies have provided valuable information on the course, clinical outcomes, and prognostic markers in rheumatoid arthritis (RA). They reflect a complete spectrum of disease in 'true-to-life' settings, and can identify aspects of RA such as long-term outcomes and predictive markers which are not easily obtained from clinical trials. Profiles of drug therapies gained over time from these studies complement those of short-term randomized studies. Comparisons of results from early-RA cohorts show both similarities and considerable differences.
authors.affiliation: City Hospital, Herts, UK. adam.young@whht.nhs.uk
authors.forename: Adam
authors.initials: A
authors.lastname: Young
mesh_terms: D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000628:therapy*; D015331:Cohort Studies; D042241:Early Diagnosis; D006801:Humans; D008137:Longitudinal Studies; D011379:Prognosis